locus-tag	class	description
G6N66_RS00070	COG1024	Enoyl-CoA hydratase
G6N66_RS00090	COG0657	acetylesterase activity
G6N66_RS00135	COG0297	glycogen (starch) synthase activity
G6N66_RS00180	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS00185	COG0028	Belongs to the TPP enzyme family
G6N66_RS00230	COG4981	capsule polysaccharide biosynthetic process
G6N66_RS00240	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N66_RS00255	COG2030	dehydratase
G6N66_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS00265	COG0183	Belongs to the thiolase family
G6N66_RS00270	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS00280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6N66_RS00285	COG0657	acetylesterase activity
G6N66_RS00300	COG1053	succinate dehydrogenase
G6N66_RS00330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N66_RS00330	COG2146	nitrite reductase [NAD(P)H] activity
G6N66_RS00350	COG0745	RESPONSE REGULATOR receiver
G6N66_RS00390	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS00405	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS00420	COG0346	lactoylglutathione lyase activity
G6N66_RS00445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS00500	COG1404	Belongs to the peptidase S8 family
G6N66_RS00530	COG0778	Nitroreductase
G6N66_RS00580	COG2130	NADP-dependent
G6N66_RS00645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6N66_RS00645	COG0235	Class ii aldolase
G6N66_RS00655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N66_RS00675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N66_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS00755	COG3177	Filamentation induced by cAMP protein fic
G6N66_RS00830	COG0717	Belongs to the dCTP deaminase family
G6N66_RS00850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N66_RS00890	COG0657	acetylesterase activity
G6N66_RS00900	COG0247	lactate metabolic process
G6N66_RS00900	COG2181	nitrate reductase activity
G6N66_RS00915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N66_RS00995	COG0789	Transcriptional regulator
G6N66_RS01030	COG0542	response to heat
G6N66_RS01090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G6N66_RS01120	COG2010	Cytochrome c
G6N66_RS01120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N66_RS01125	COG2080	2 iron, 2 sulfur cluster binding
G6N66_RS01135	COG0586	Pfam SNARE associated Golgi protein
G6N66_RS01140	COG0191	fructose-bisphosphate aldolase activity
G6N66_RS01160	COG1994	Peptidase M50
G6N66_RS01185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G6N66_RS01195	COG0657	acetylesterase activity
G6N66_RS01200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N66_RS01210	COG1252	NADH dehydrogenase
G6N66_RS01240	COG1716	ATPase activity
G6N66_RS01255	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS01280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS01285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS01290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS01295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS01310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G6N66_RS01320	COG2826	transposase and inactivated derivatives, IS30 family
G6N66_RS01330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N66_RS01345	COG0352	thiamine-phosphate diphosphorylase activity
G6N66_RS01385	COG2234	aminopeptidase activity
G6N66_RS01390	COG2234	aminopeptidase activity
G6N66_RS01405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS01425	COG1309	transcriptional regulator
G6N66_RS01445	COG3707	response regulator
G6N66_RS01485	COG0242	peptide deformylase activity
G6N66_RS01500	COG2032	superoxide dismutase activity
G6N66_RS01545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N66_RS01565	COG4221	oxidoreductase activity
G6N66_RS01605	COG0459	protein refolding
G6N66_RS01615	COG0300	oxidoreductase activity
G6N66_RS01635	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N66_RS01660	COG1595	DNA-templated transcription, initiation
G6N66_RS01675	COG1033	growth of symbiont in host cell
G6N66_RS01675	COG2409	Drug exporters of the RND superfamily
G6N66_RS01715	COG1024	Enoyl-CoA hydratase
G6N66_RS01720	COG1505	serine-type exopeptidase activity
G6N66_RS01780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS01800	COG2733	membrane
G6N66_RS01875	COG0588	phosphoglycerate mutase activity
G6N66_RS01915	COG0248	Ppx GppA phosphatase
G6N66_RS01955	COG0204	Acyl-transferase
G6N66_RS01965	COG2030	dehydratase
G6N66_RS01985	COG0181	hydroxymethylbilane synthase activity
G6N66_RS02020	COG2755	lipolytic protein G-D-S-L family
G6N66_RS02030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS02035	COG1113	amino acid transport
G6N66_RS02040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6N66_RS02045	COG4948	Mandelate Racemase Muconate Lactonizing
G6N66_RS02055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6N66_RS02060	COG0406	alpha-ribazole phosphatase activity
G6N66_RS02070	COG0785	Cytochrome C biogenesis protein
G6N66_RS02080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N66_RS02110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N66_RS02115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N66_RS02170	COG0306	phosphate transporter
G6N66_RS02180	COG4221	oxidoreductase activity
G6N66_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS02205	COG1228	amidohydrolase
G6N66_RS02210	COG4948	Mandelate Racemase Muconate Lactonizing
G6N66_RS02235	COG4221	oxidoreductase activity
G6N66_RS02295	COG0659	secondary active sulfate transmembrane transporter activity
G6N66_RS02355	COG0596	Alpha beta hydrolase
G6N66_RS02380	COG0142	geranyltranstransferase activity
G6N66_RS02395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6N66_RS02395	COG1672	PFAM Archaeal ATPase
G6N66_RS02400	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G6N66_RS02400	COG0493	'glutamate synthase
G6N66_RS02405	COG3268	Saccharopine dehydrogenase
G6N66_RS02410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS02415	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS02425	COG0243	molybdopterin cofactor binding
G6N66_RS02445	COG0513	Belongs to the DEAD box helicase family
G6N66_RS02460	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS02465	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS02490	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS02530	COG0671	phosphoesterase, PA-phosphatase related
G6N66_RS02545	COG3537	Alpha-1,2-mannosidase
G6N66_RS02575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N66_RS02580	COG1074	ATP-dependent DNA helicase activity
G6N66_RS02585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N66_RS02595	COG2226	methyltransferase
G6N66_RS02605	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N66_RS02615	COG0243	molybdopterin cofactor binding
G6N66_RS02630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS02655	COG2030	dehydratase
G6N66_RS02660	COG2030	dehydratase
G6N66_RS02690	COG0081	regulation of translation
G6N66_RS02705	COG4941	Belongs to the sigma-70 factor family
G6N66_RS02715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS02725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS02730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS02745	COG2318	DinB family
G6N66_RS02760	COG1940	carbohydrate kinase activity
G6N66_RS02800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N66_RS02820	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS02835	COG1024	Enoyl-CoA hydratase
G6N66_RS02855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6N66_RS02870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N66_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS02910	COG0535	radical SAM domain protein
G6N66_RS02945	COG0477	Major facilitator Superfamily
G6N66_RS02965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N66_RS02975	COG0089	rRNA binding
G6N66_RS03005	COG0255	Belongs to the universal ribosomal protein uL29 family
G6N66_RS03035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N66_RS03060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N66_RS03065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N66_RS03075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N66_RS03095	COG1051	belongs to the nudix hydrolase family
G6N66_RS03100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS03105	COG0616	signal peptide processing
G6N66_RS03125	COG0300	oxidoreductase activity
G6N66_RS03130	COG1063	alcohol dehydrogenase
G6N66_RS03140	COG2226	methyltransferase
G6N66_RS03165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N66_RS03190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS03200	COG0563	adenylate kinase activity
G6N66_RS03220	COG0028	Belongs to the TPP enzyme family
G6N66_RS03235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N66_RS03270	COG0723	plastoquinol--plastocyanin reductase activity
G6N66_RS03340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N66_RS03345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N66_RS03360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6N66_RS03370	COG0203	ribosomal protein L17
G6N66_RS03395	COG1404	Belongs to the peptidase S8 family
G6N66_RS03405	COG1674	ftsk spoiiie
G6N66_RS03415	COG4842	Belongs to the WXG100 family
G6N66_RS03420	COG4842	Belongs to the WXG100 family
G6N66_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS03490	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N66_RS03490	COG2308	Evidence 4 Homologs of previously reported genes of
G6N66_RS03495	COG0367	asparagine synthase
G6N66_RS03510	COG0076	glutamate decarboxylase activity
G6N66_RS03535	COG0456	acetyltransferase
G6N66_RS03555	COG0459	protein refolding
G6N66_RS03650	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS03655	COG3321	synthase
G6N66_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS03655	COG0604	alcohol dehydrogenase
G6N66_RS03685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N66_RS03695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N66_RS03700	COG0477	Major facilitator Superfamily
G6N66_RS03705	COG1733	regulation of RNA biosynthetic process
G6N66_RS03710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N66_RS03710	COG0519	Catalyzes the synthesis of GMP from XMP
G6N66_RS03760	COG2030	dehydratase
G6N66_RS03785	COG3391	amine dehydrogenase activity
G6N66_RS03800	COG0587	DNA-directed DNA polymerase activity
G6N66_RS03805	COG4221	oxidoreductase activity
G6N66_RS03820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N66_RS03830	COG2018	Roadblock/LC7 domain
G6N66_RS03845	COG0842	Transport permease protein
G6N66_RS03845	COG1131	(ABC) transporter
G6N66_RS03845	COG1716	ATPase activity
G6N66_RS03850	COG0842	Transport permease protein
G6N66_RS03850	COG1131	(ABC) transporter
G6N66_RS03850	COG1716	ATPase activity
G6N66_RS03875	COG0277	FAD linked oxidase domain protein
G6N66_RS03900	COG2873	o-acetylhomoserine
G6N66_RS03920	COG1295	ribonuclease BN
G6N66_RS03930	COG0657	acetylesterase activity
G6N66_RS03940	COG2814	Major facilitator Superfamily
G6N66_RS03950	COG1686	Belongs to the peptidase S11 family
G6N66_RS03965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N66_RS03970	COG1595	DNA-templated transcription, initiation
G6N66_RS03995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N66_RS04000	COG1053	succinate dehydrogenase
G6N66_RS04010	COG2009	succinate dehydrogenase
G6N66_RS04035	COG2124	cytochrome p450
G6N66_RS04040	COG2304	oxidoreductase activity
G6N66_RS04050	COG2304	oxidoreductase activity
G6N66_RS04060	COG3511	phospholipase C
G6N66_RS04070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N66_RS04085	COG1473	amidohydrolase
G6N66_RS04090	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N66_RS04090	COG1473	amidohydrolase
G6N66_RS04115	COG0564	pseudouridine synthase activity
G6N66_RS04135	COG5651	PPE family
G6N66_RS04150	COG1201	RNA secondary structure unwinding
G6N66_RS04155	COG1309	transcriptional regulator
G6N66_RS04190	COG4770	biotin carboxylase activity
G6N66_RS04205	COG0424	maF-like protein
G6N66_RS04215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N66_RS04220	COG1053	succinate dehydrogenase
G6N66_RS04225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G6N66_RS04225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G6N66_RS04240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6N66_RS04255	COG0477	Major facilitator Superfamily
G6N66_RS04265	COG4251	negative regulation of phosphorylation
G6N66_RS04270	COG0784	Response regulator, receiver
G6N66_RS04290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS04295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS04325	COG1316	TRANSCRIPTIONal
G6N66_RS04360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6N66_RS04380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N66_RS04390	COG1482	cell wall glycoprotein biosynthetic process
G6N66_RS04395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS04400	COG0531	amino acid
G6N66_RS04405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N66_RS04425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N66_RS04445	COG5401	PFAM Sporulation and spore germination
G6N66_RS04470	COG2226	methyltransferase
G6N66_RS04485	COG2070	2-Nitropropane dioxygenase
G6N66_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS04505	COG2124	cytochrome p450
G6N66_RS04520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6N66_RS04525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N66_RS04530	COG0653	protein targeting
G6N66_RS04535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G6N66_RS04545	COG1716	ATPase activity
G6N66_RS04545	COG1131	(ABC) transporter
G6N66_RS04545	COG0842	Transport permease protein
G6N66_RS04550	COG2020	methyltransferase activity
G6N66_RS04580	COG2326	polyphosphate kinase activity
G6N66_RS04600	COG2358	TRAP transporter, solute receptor (TAXI family
G6N66_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS04615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS04620	COG2267	carboxylic ester hydrolase activity
G6N66_RS04630	COG3246	L-lysine catabolic process to acetate
G6N66_RS04645	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS04665	COG0183	Belongs to the thiolase family
G6N66_RS04670	COG1733	regulation of RNA biosynthetic process
G6N66_RS04680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N66_RS04685	COG2135	peptidase activity
G6N66_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS04735	COG1063	alcohol dehydrogenase
G6N66_RS04750	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS04765	COG1595	DNA-templated transcription, initiation
G6N66_RS04775	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N66_RS04810	COG0406	alpha-ribazole phosphatase activity
G6N66_RS04825	COG0513	Belongs to the DEAD box helicase family
G6N66_RS04870	COG0596	Alpha beta hydrolase
G6N66_RS04920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N66_RS04935	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N66_RS04970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS04980	COG0783	Belongs to the Dps family
G6N66_RS04995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G6N66_RS05030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N66_RS05065	COG0384	phenazine biosynthesis protein PhzF
G6N66_RS05075	COG3707	response regulator
G6N66_RS05085	COG0789	Transcriptional regulator
G6N66_RS05125	COG1309	transcriptional regulator
G6N66_RS05170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS05175	COG1573	uracil-dna glycosylase
G6N66_RS05180	COG0277	FAD linked oxidase domain protein
G6N66_RS05180	COG0247	lactate metabolic process
G6N66_RS05190	COG0028	Belongs to the TPP enzyme family
G6N66_RS05195	COG4221	oxidoreductase activity
G6N66_RS05220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N66_RS05225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N66_RS05245	COG2201	protein-glutamate methylesterase activity
G6N66_RS05260	COG2201	protein-glutamate methylesterase activity
G6N66_RS05265	COG0297	glycogen (starch) synthase activity
G6N66_RS05305	COG2267	carboxylic ester hydrolase activity
G6N66_RS05360	COG0714	Associated with various cellular activities
G6N66_RS05390	COG0713	ATP synthesis coupled electron transport
G6N66_RS05410	COG1034	ATP synthesis coupled electron transport
G6N66_RS05430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N66_RS05470	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS05485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS05510	COG0667	Aldo Keto reductase
G6N66_RS05520	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS05530	COG0483	inositol monophosphate 1-phosphatase activity
G6N66_RS05600	COG0277	FAD linked oxidase domain protein
G6N66_RS05605	COG0493	'glutamate synthase
G6N66_RS05615	COG0668	transmembrane transport
G6N66_RS05625	COG2884	Cell division ATP-binding protein ftsE
G6N66_RS05630	COG2177	Part of the ABC transporter FtsEX involved in
G6N66_RS05700	COG0515	serine threonine protein kinase
G6N66_RS05700	COG2815	serine threonine protein kinase
G6N66_RS05705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N66_RS05730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS05760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS05780	COG1024	Enoyl-CoA hydratase
G6N66_RS05790	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS05795	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS05800	COG2267	carboxylic ester hydrolase activity
G6N66_RS05810	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS05825	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS05830	COG1032	radical SAM domain protein
G6N66_RS05870	COG4689	acetoacetate decarboxylase
G6N66_RS05900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N66_RS05915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS05990	COG4638	Rieske (2fe-2S)
G6N66_RS06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N66_RS06055	COG1309	transcriptional regulator
G6N66_RS06065	COG4221	oxidoreductase activity
G6N66_RS06080	COG2354	Protein conserved in bacteria
G6N66_RS06130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6N66_RS06165	COG2801	Transposase and inactivated derivatives
G6N66_RS06260	COG4221	oxidoreductase activity
G6N66_RS06265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N66_RS06270	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06275	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06280	COG1024	Enoyl-CoA hydratase
G6N66_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06290	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS06300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N66_RS06315	COG2226	methyltransferase
G6N66_RS06335	COG0783	Belongs to the Dps family
G6N66_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS06350	COG2124	cytochrome p450
G6N66_RS06365	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06385	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06390	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06415	COG0183	Belongs to the thiolase family
G6N66_RS06430	COG2124	cytochrome p450
G6N66_RS06495	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06535	COG3290	protein histidine kinase activity
G6N66_RS06540	COG4565	transcriptional regulatory protein
G6N66_RS06575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N66_RS06595	COG4221	oxidoreductase activity
G6N66_RS06620	COG4251	negative regulation of phosphorylation
G6N66_RS06630	COG2301	Belongs to the HpcH HpaI aldolase family
G6N66_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06650	COG0058	SHG alpha-glucan phosphorylase activity
G6N66_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS06710	COG1024	Enoyl-CoA hydratase
G6N66_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS06725	COG2326	polyphosphate kinase activity
G6N66_RS06735	COG0443	Heat shock 70 kDa protein
G6N66_RS06745	COG1966	Carbon starvation protein
G6N66_RS06750	COG1793	dna ligase
G6N66_RS06760	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS06775	COG2186	Transcriptional regulator
G6N66_RS06840	COG1309	transcriptional regulator
G6N66_RS06845	COG2072	flavoprotein involved in K transport
G6N66_RS06850	COG0300	oxidoreductase activity
G6N66_RS06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N66_RS06920	COG1119	ATPase activity
G6N66_RS06955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N66_RS06960	COG0110	maltose O-acetyltransferase activity
G6N66_RS06970	COG0415	Belongs to the DNA photolyase family
G6N66_RS06980	COG1304	FMN binding
G6N66_RS06985	COG1819	glycosyl
G6N66_RS07070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N66_RS07150	COG0205	6-phosphofructokinase activity
G6N66_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS07175	COG2409	Drug exporters of the RND superfamily
G6N66_RS07175	COG1033	growth of symbiont in host cell
G6N66_RS07225	COG0028	Belongs to the TPP enzyme family
G6N66_RS07245	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N66_RS07260	COG0473	3-isopropylmalate dehydrogenase activity
G6N66_RS07270	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N66_RS07275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N66_RS07305	COG0066	3-isopropylmalate dehydratase activity
G6N66_RS07320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N66_RS07355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N66_RS07395	COG2197	response regulator
G6N66_RS07400	COG4585	Histidine kinase
G6N66_RS07425	COG1461	Dihydroxyacetone kinase
G6N66_RS07430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6N66_RS07460	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N66_RS07465	COG0742	ribosomal rna small subunit methyltransferase
G6N66_RS07485	COG0701	Predicted permease
G6N66_RS07500	COG0571	ribonuclease III activity
G6N66_RS07545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N66_RS07590	COG1686	Belongs to the peptidase S11 family
G6N66_RS07610	COG0228	four-way junction DNA binding
G6N66_RS07620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N66_RS07635	COG0335	large ribosomal subunit rRNA binding
G6N66_RS07645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6N66_RS07705	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N66_RS07715	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N66_RS07725	COG0154	amidase activity
G6N66_RS07745	COG0745	RESPONSE REGULATOR receiver
G6N66_RS07760	COG0233	cytoplasmic translational termination
G6N66_RS07765	COG0575	Belongs to the CDS family
G6N66_RS07770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N66_RS07790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N66_RS07830	COG1492	cobalamin metabolic process
G6N66_RS07845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N66_RS07850	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS07870	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N66_RS07910	COG1648	precorrin-2 dehydrogenase activity
G6N66_RS07910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N66_RS07925	COG0657	acetylesterase activity
G6N66_RS07940	COG0779	Required for maturation of 30S ribosomal subunits
G6N66_RS07955	COG0481	GTPase activity
G6N66_RS07960	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6N66_RS07965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N66_RS07985	COG3842	ATPase activity
G6N66_RS07990	COG1024	Enoyl-CoA hydratase
G6N66_RS08030	COG0183	Belongs to the thiolase family
G6N66_RS08035	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS08055	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N66_RS08070	COG0686	Belongs to the AlaDH PNT family
G6N66_RS08185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N66_RS08230	COG1024	Enoyl-CoA hydratase
G6N66_RS08240	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS08245	COG0439	Biotin carboxylase
G6N66_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS08260	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS08265	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS08290	COG3214	Protein conserved in bacteria
G6N66_RS08310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G6N66_RS08325	COG2442	InterPro IPR007367
G6N66_RS08335	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G6N66_RS08350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N66_RS08360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS08385	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N66_RS08410	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N66_RS08430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N66_RS08430	COG1372	Participates in initiation and elongation during chromosome replication
G6N66_RS08440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N66_RS08450	COG1196	nuclear chromosome segregation
G6N66_RS08465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N66_RS08470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N66_RS08475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N66_RS08480	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS08490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N66_RS08495	COG1388	LysM domain
G6N66_RS08655	COG0569	domain protein
G6N66_RS08660	COG0531	amino acid
G6N66_RS08665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N66_RS08715	COG1024	Enoyl-CoA hydratase
G6N66_RS08720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6N66_RS08745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N66_RS08760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G6N66_RS08790	COG1115	amino acid carrier protein
G6N66_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS08990	COG4974	Belongs to the 'phage' integrase family
G6N66_RS08995	COG2963	transposase activity
G6N66_RS09140	COG1404	Belongs to the peptidase S8 family
G6N66_RS09180	COG1111	helicase
G6N66_RS09180	COG1205	dead DEAH box helicase
G6N66_RS09370	COG0464	growth
G6N66_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS09460	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS09465	COG2124	cytochrome p450
G6N66_RS09480	COG2124	cytochrome p450
G6N66_RS09495	COG2124	cytochrome p450
G6N66_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS09540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS09550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS09570	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G6N66_RS09595	COG0714	Associated with various cellular activities
G6N66_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS09695	COG1309	transcriptional regulator
G6N66_RS09705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS09710	COG1309	transcriptional regulator
G6N66_RS09755	COG0657	acetylesterase activity
G6N66_RS09785	COG0656	L-ascorbic acid biosynthetic process
G6N66_RS09800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N66_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS09845	COG0753	catalase activity
G6N66_RS09850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N66_RS09860	COG1309	transcriptional regulator
G6N66_RS09890	COG0235	Class ii aldolase
G6N66_RS09930	COG3485	protocatechuate 3,4-dioxygenase
G6N66_RS09935	COG3485	protocatechuate 3,4-dioxygenase
G6N66_RS09940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N66_RS10000	COG0667	Aldo Keto reductase
G6N66_RS10010	COG0657	acetylesterase activity
G6N66_RS10020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6N66_RS10040	COG0438	transferase activity, transferring glycosyl groups
G6N66_RS10060	COG1946	Acyl-CoA thioesterase
G6N66_RS10080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N66_RS10120	COG0632	four-way junction helicase activity
G6N66_RS10160	COG3320	Male sterility
G6N66_RS10160	COG1022	Amp-dependent synthetase and ligase
G6N66_RS10165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6N66_RS10175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N66_RS10180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N66_RS10185	COG0747	negative chemotaxis
G6N66_RS10190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6N66_RS10200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N66_RS10205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS10210	COG0124	histidyl-tRNA synthetase
G6N66_RS10235	COG1396	sequence-specific DNA binding
G6N66_RS10240	COG0235	Class ii aldolase
G6N66_RS10245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N66_RS10305	COG5473	translation initiation factor activity
G6N66_RS10305	COG5473	translation initiation factor activity
G6N66_RS10325	COG0432	Pfam Uncharacterised protein family UPF0047
G6N66_RS10330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N66_RS10380	COG0006	proline dipeptidase activity
G6N66_RS10420	COG2188	Transcriptional regulator
G6N66_RS10430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6N66_RS10435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N66_RS10450	COG2226	methyltransferase
G6N66_RS10455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6N66_RS10460	COG0540	Belongs to the ATCase OTCase family
G6N66_RS10475	COG0505	Belongs to the CarA family
G6N66_RS10485	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N66_RS10510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N66_RS10605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N66_RS10625	COG0322	excinuclease ABC activity
G6N66_RS10655	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS10700	COG0126	phosphoglycerate kinase activity
G6N66_RS10760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N66_RS10795	COG1131	(ABC) transporter
G6N66_RS10810	COG0719	Fe-S assembly protein
G6N66_RS10810	COG1372	Participates in initiation and elongation during chromosome replication
G6N66_RS10820	COG0396	ATPase activity
G6N66_RS10825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N66_RS10830	COG0822	iron-sulfur transferase activity
G6N66_RS10835	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N66_RS10850	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS10855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N66_RS10865	COG0488	(ABC) transporter
G6N66_RS10870	COG1309	transcriptional regulator
G6N66_RS10875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N66_RS10885	COG3883	PFAM NLP P60 protein
G6N66_RS10885	COG0791	NLP P60 protein
G6N66_RS10895	COG0714	Associated with various cellular activities
G6N66_RS10905	COG2304	oxidoreductase activity
G6N66_RS10920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N66_RS11040	COG3321	synthase
G6N66_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS11040	COG0604	alcohol dehydrogenase
G6N66_RS11050	COG2226	methyltransferase
G6N66_RS11055	COG2070	2-Nitropropane dioxygenase
G6N66_RS11070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N66_RS11090	COG0252	asparaginase activity
G6N66_RS11110	COG2346	COG2346, Truncated hemoglobins
G6N66_RS11120	COG0300	oxidoreductase activity
G6N66_RS11205	COG3883	PFAM NLP P60 protein
G6N66_RS11205	COG0791	NLP P60 protein
G6N66_RS11265	COG0673	inositol 2-dehydrogenase activity
G6N66_RS11275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N66_RS11305	COG1819	glycosyl
G6N66_RS11325	COG2755	lipolytic protein G-D-S-L family
G6N66_RS11325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N66_RS11330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N66_RS11335	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G6N66_RS11380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N66_RS11380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N66_RS11385	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N66_RS11385	COG2755	lipolytic protein G-D-S-L family
G6N66_RS11400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N66_RS11400	COG2755	lipolytic protein G-D-S-L family
G6N66_RS11410	COG1819	glycosyl
G6N66_RS11425	COG0604	alcohol dehydrogenase
G6N66_RS11425	COG3321	synthase
G6N66_RS11435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N66_RS11440	COG2226	methyltransferase
G6N66_RS11450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N66_RS11495	COG0656	L-ascorbic acid biosynthetic process
G6N66_RS11570	COG1309	transcriptional regulator
G6N66_RS11595	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N66_RS11610	COG0483	inositol monophosphate 1-phosphatase activity
G6N66_RS11615	COG0107	imidazoleglycerol-phosphate synthase activity
G6N66_RS11635	COG0387	Pfam Sodium calcium exchanger
G6N66_RS11645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N66_RS11685	COG1946	Acyl-CoA thioesterase
G6N66_RS11695	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
G6N66_RS11700	COG4988	ABC transporter
G6N66_RS11705	COG1294	oxidase, subunit
G6N66_RS11710	COG1271	oxidase subunit
G6N66_RS11745	COG2357	RelA SpoT domain protein
G6N66_RS11805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N66_RS11805	COG0237	dephospho-CoA kinase activity
G6N66_RS11815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N66_RS11820	COG3285	dna ligase
G6N66_RS11820	COG1793	dna ligase
G6N66_RS11845	COG1131	(ABC) transporter
G6N66_RS11845	COG1716	ATPase activity
G6N66_RS11845	COG0842	Transport permease protein
G6N66_RS11870	COG1285	pathogenesis
G6N66_RS11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS11935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N66_RS11950	COG3391	amine dehydrogenase activity
G6N66_RS11965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N66_RS11970	COG0072	phenylalanine-tRNA ligase activity
G6N66_RS11970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N66_RS11985	COG3391	amine dehydrogenase activity
G6N66_RS11990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G6N66_RS11995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N66_RS12035	COG3321	synthase
G6N66_RS12035	COG0604	alcohol dehydrogenase
G6N66_RS12040	COG3321	synthase
G6N66_RS12040	COG0604	alcohol dehydrogenase
G6N66_RS12045	COG3321	synthase
G6N66_RS12045	COG3321	synthase
G6N66_RS12045	COG0604	alcohol dehydrogenase
G6N66_RS12045	COG0604	alcohol dehydrogenase
G6N66_RS12060	COG0488	(ABC) transporter
G6N66_RS12075	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N66_RS12090	COG1131	(ABC) transporter
G6N66_RS12125	COG0647	UMP catabolic process
G6N66_RS12195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N66_RS12205	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G6N66_RS12210	COG1160	GTP binding
G6N66_RS12230	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N66_RS12245	COG3246	L-lysine catabolic process to acetate
G6N66_RS12315	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6N66_RS12315	COG1672	PFAM Archaeal ATPase
G6N66_RS12325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N66_RS12355	COG1063	alcohol dehydrogenase
G6N66_RS12375	COG3391	amine dehydrogenase activity
G6N66_RS12390	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS12450	COG1132	(ABC) transporter
G6N66_RS12455	COG2409	Drug exporters of the RND superfamily
G6N66_RS12460	COG2271	Major facilitator Superfamily
G6N66_RS12490	COG0515	serine threonine protein kinase
G6N66_RS12540	COG2197	response regulator
G6N66_RS12545	COG2197	response regulator
G6N66_RS12580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N66_RS12620	COG2226	methyltransferase
G6N66_RS12625	COG0789	Transcriptional regulator
G6N66_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12635	COG0243	molybdopterin cofactor binding
G6N66_RS12640	COG0657	acetylesterase activity
G6N66_RS12650	COG1131	(ABC) transporter
G6N66_RS12650	COG0842	Transport permease protein
G6N66_RS12650	COG1716	ATPase activity
G6N66_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12675	COG1309	transcriptional regulator
G6N66_RS12700	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12715	COG2030	dehydratase
G6N66_RS12720	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS12740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS12750	COG2814	Major facilitator Superfamily
G6N66_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS12795	COG4221	oxidoreductase activity
G6N66_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS12875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS12885	COG2226	methyltransferase
G6N66_RS12895	COG0577	efflux transmembrane transporter activity
G6N66_RS12895	COG1136	(ABC) transporter
G6N66_RS12900	COG0577	efflux transmembrane transporter activity
G6N66_RS12900	COG1136	(ABC) transporter
G6N66_RS12920	COG0393	Putative heavy-metal-binding
G6N66_RS12960	COG2197	response regulator
G6N66_RS12965	COG2813	Specifically methylates the guanine in position
G6N66_RS12970	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS12995	COG1024	Enoyl-CoA hydratase
G6N66_RS13005	COG0022	dehydrogenase e1 component
G6N66_RS13010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N66_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS13020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS13040	COG0649	NAD binding
G6N66_RS13075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N66_RS13110	COG5651	PPE family
G6N66_RS13130	COG5651	PPE family
G6N66_RS13150	COG4842	Belongs to the WXG100 family
G6N66_RS13170	COG1404	Belongs to the peptidase S8 family
G6N66_RS13210	COG5651	PPE family
G6N66_RS13220	COG1285	pathogenesis
G6N66_RS13340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS13355	COG1253	flavin adenine dinucleotide binding
G6N66_RS13360	COG1253	flavin adenine dinucleotide binding
G6N66_RS13370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N66_RS13390	COG1252	NADH dehydrogenase
G6N66_RS13395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS13410	COG0657	acetylesterase activity
G6N66_RS13460	COG4221	oxidoreductase activity
G6N66_RS13465	COG2072	flavoprotein involved in K transport
G6N66_RS13495	COG1968	undecaprenyl-diphosphatase activity
G6N66_RS13500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS13505	COG0183	Belongs to the thiolase family
G6N66_RS13565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N66_RS13590	COG1024	Enoyl-CoA hydratase
G6N66_RS13600	COG2193	ferroxidase activity
G6N66_RS13615	COG0174	glutamine synthetase
G6N66_RS13640	COG0154	amidase activity
G6N66_RS13650	COG0640	Transcriptional regulator
G6N66_RS13755	COG2070	2-Nitropropane dioxygenase
G6N66_RS13770	COG1063	alcohol dehydrogenase
G6N66_RS13780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS13785	COG1490	D-aminoacyl-tRNA deacylase activity
G6N66_RS13815	COG2814	Major facilitator Superfamily
G6N66_RS13825	COG1950	PFAM Membrane protein of
G6N66_RS13830	COG1024	Enoyl-CoA hydratase
G6N66_RS13880	COG2070	2-Nitropropane dioxygenase
G6N66_RS13885	COG1942	4-Oxalocrotonate Tautomerase
G6N66_RS13890	COG0583	DNA-binding transcription factor activity
G6N66_RS13915	COG1233	COG1233 Phytoene dehydrogenase and related
G6N66_RS13940	COG0640	Transcriptional regulator
G6N66_RS13990	COG2031	fatty acid transporter
G6N66_RS13995	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS14035	COG4977	sequence-specific DNA binding
G6N66_RS14045	COG2826	transposase and inactivated derivatives, IS30 family
G6N66_RS14050	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS14055	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS14060	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS14065	COG1024	Enoyl-CoA hydratase
G6N66_RS14075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N66_RS14075	COG0543	2 iron, 2 sulfur cluster binding
G6N66_RS14080	COG0596	Alpha beta hydrolase
G6N66_RS14085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N66_RS14085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N66_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS14095	COG1309	transcriptional regulator
G6N66_RS14110	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS14115	COG2197	response regulator
G6N66_RS14120	COG2124	cytochrome p450
G6N66_RS14140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS14165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS14205	COG0596	Alpha beta hydrolase
G6N66_RS14235	COG1454	alcohol dehydrogenase
G6N66_RS14250	COG1113	amino acid transport
G6N66_RS14270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS14285	COG2226	methyltransferase
G6N66_RS14290	COG0438	transferase activity, transferring glycosyl groups
G6N66_RS14305	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS14310	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS14325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS14330	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS14345	COG1309	transcriptional regulator
G6N66_RS14390	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS14400	COG0723	plastoquinol--plastocyanin reductase activity
G6N66_RS14405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS14420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N66_RS14455	COG0657	acetylesterase activity
G6N66_RS14455	COG0657	acetylesterase activity
G6N66_RS14465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N66_RS14475	COG3706	GGDEF domain
G6N66_RS14480	COG1643	Atp-dependent helicase
G6N66_RS14505	COG3321	synthase
G6N66_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS14505	COG0604	alcohol dehydrogenase
G6N66_RS14510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6N66_RS14510	COG2070	2-Nitropropane dioxygenase
G6N66_RS14515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6N66_RS14525	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N66_RS14585	COG3757	hydrolase, family 25
G6N66_RS14655	COG1595	DNA-templated transcription, initiation
G6N66_RS14660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N66_RS14660	COG2169	Transcriptional regulator
G6N66_RS14675	COG1131	(ABC) transporter
G6N66_RS14725	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS14740	COG0589	response to stress
G6N66_RS14740	COG0475	glutathione-regulated potassium exporter activity
G6N66_RS14745	COG0604	alcohol dehydrogenase
G6N66_RS14750	COG1024	Enoyl-CoA hydratase
G6N66_RS14785	COG2837	iron assimilation
G6N66_RS14805	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N66_RS14810	COG3842	ATPase activity
G6N66_RS14815	COG0395	ABC-type sugar transport system, permease component
G6N66_RS14820	COG1175	transmembrane transport
G6N66_RS14830	COG1595	DNA-templated transcription, initiation
G6N66_RS14845	COG1335	isochorismatase
G6N66_RS14855	COG3265	gluconokinase activity
G6N66_RS14865	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N66_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS14895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N66_RS14900	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS14970	COG0714	Associated with various cellular activities
G6N66_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS15025	COG4221	oxidoreductase activity
G6N66_RS15025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N66_RS15025	COG0604	alcohol dehydrogenase
G6N66_RS15025	COG3321	synthase
G6N66_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS15125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS15175	COG0300	oxidoreductase activity
G6N66_RS15190	COG0745	RESPONSE REGULATOR receiver
G6N66_RS15195	COG2205	protein histidine kinase activity
G6N66_RS15250	COG2378	regulation of single-species biofilm formation
G6N66_RS15270	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N66_RS15295	COG1222	aaa ATPase
G6N66_RS15325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N66_RS15345	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS15350	COG1410	methionine synthase
G6N66_RS15350	COG0646	methionine synthase
G6N66_RS15405	COG0167	dihydroorotate dehydrogenase activity
G6N66_RS15420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N66_RS15485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6N66_RS15500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N66_RS15525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6N66_RS15530	COG0768	penicillin binding
G6N66_RS15590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS15595	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N66_RS15625	COG0003	Pfam Anion-transporting ATPase
G6N66_RS15640	COG1022	Amp-dependent synthetase and ligase
G6N66_RS15675	COG1845	cytochrome c oxidase, subunit III
G6N66_RS15680	COG2010	Cytochrome c
G6N66_RS15730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N66_RS15775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6N66_RS15785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N66_RS15830	COG0321	lipoyl(octanoyl) transferase activity
G6N66_RS15860	COG3546	catalase activity
G6N66_RS15895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6N66_RS15905	COG4584	PFAM Integrase catalytic
G6N66_RS15915	COG4585	Histidine kinase
G6N66_RS15920	COG2197	response regulator
G6N66_RS15925	COG2201	protein-glutamate methylesterase activity
G6N66_RS15960	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS15975	COG4585	Histidine kinase
G6N66_RS15990	COG2124	cytochrome p450
G6N66_RS16045	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS16055	COG0596	Alpha beta hydrolase
G6N66_RS16120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N66_RS16125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N66_RS16200	COG4221	oxidoreductase activity
G6N66_RS16235	COG1231	oxidoreductase activity
G6N66_RS16260	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N66_RS16275	COG1309	transcriptional regulator
G6N66_RS16310	COG2124	cytochrome p450
G6N66_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS16385	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS16410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS16490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G6N66_RS16530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G6N66_RS16530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G6N66_RS16565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N66_RS16620	COG0653	protein targeting
G6N66_RS16625	COG3012	SEC-C Motif Domain Protein
G6N66_RS16675	COG3707	response regulator
G6N66_RS16700	COG0438	transferase activity, transferring glycosyl groups
G6N66_RS16725	COG2267	carboxylic ester hydrolase activity
G6N66_RS16755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G6N66_RS16760	COG0596	Alpha beta hydrolase
G6N66_RS16810	COG0697	spore germination
G6N66_RS16840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N66_RS16860	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS16875	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N66_RS16895	COG2226	methyltransferase
G6N66_RS16905	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N66_RS16935	COG2226	methyltransferase
G6N66_RS16970	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS16975	COG0477	Major facilitator Superfamily
G6N66_RS16980	COG0477	Major facilitator Superfamily
G6N66_RS16985	COG2814	Major facilitator Superfamily
G6N66_RS17000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS17010	COG0386	Belongs to the glutathione peroxidase family
G6N66_RS17020	COG3012	SEC-C Motif Domain Protein
G6N66_RS17040	COG3511	phospholipase C
G6N66_RS17065	COG1024	Enoyl-CoA hydratase
G6N66_RS17135	COG1175	transmembrane transport
G6N66_RS17155	COG0531	amino acid
G6N66_RS17160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N66_RS17165	COG1834	amidinotransferase
G6N66_RS17170	COG1522	sequence-specific DNA binding
G6N66_RS17195	COG1716	ATPase activity
G6N66_RS17195	COG1131	(ABC) transporter
G6N66_RS17195	COG0842	Transport permease protein
G6N66_RS17215	COG0243	molybdopterin cofactor binding
G6N66_RS17220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N66_RS17225	COG1309	transcriptional regulator
G6N66_RS17240	COG1116	anion transmembrane transporter activity
G6N66_RS17245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6N66_RS17250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N66_RS17275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS17300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS17305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS17315	COG4424	Sulfotransferase
G6N66_RS17320	COG2855	membrane
G6N66_RS17330	COG1045	serine acetyltransferase
G6N66_RS17355	COG0657	acetylesterase activity
G6N66_RS17360	COG3391	amine dehydrogenase activity
G6N66_RS17390	COG0358	DNA primase activity
G6N66_RS17395	COG2032	superoxide dismutase activity
G6N66_RS17400	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6N66_RS17415	COG4842	Belongs to the WXG100 family
G6N66_RS17445	COG0423	glycine-tRNA ligase activity
G6N66_RS17470	COG1381	Involved in DNA repair and RecF pathway recombination
G6N66_RS17495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6N66_RS17505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6N66_RS17525	COG1420	regulation of RNA biosynthetic process
G6N66_RS17560	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N66_RS17560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N66_RS17570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N66_RS17575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N66_RS17585	COG3321	synthase
G6N66_RS17600	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N66_RS17635	COG1169	isochorismate synthase
G6N66_RS17680	COG4208	sulfate ABC transporter
G6N66_RS17685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6N66_RS17690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N66_RS17700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS17705	COG3387	PFAM Glycoside hydrolase 15-related
G6N66_RS17730	COG1234	tRNA 3'-trailer cleavage
G6N66_RS17735	COG0657	acetylesterase activity
G6N66_RS17745	COG1305	Transglutaminase-like
G6N66_RS17780	COG1555	photosystem II stabilization
G6N66_RS17780	COG1596	polysaccharide export
G6N66_RS17785	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS17810	COG5651	PPE family
G6N66_RS17815	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS17845	COG2755	lipolytic protein G-D-S-L family
G6N66_RS17855	COG0799	negative regulation of ribosome biogenesis
G6N66_RS17860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N66_RS17875	COG0542	response to heat
G6N66_RS17880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N66_RS17885	COG0668	transmembrane transport
G6N66_RS17890	COG5002	protein histidine kinase activity
G6N66_RS17895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N66_RS17910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N66_RS17910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6N66_RS17935	COG1846	Transcriptional regulator
G6N66_RS17950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N66_RS17970	COG4584	PFAM Integrase catalytic
G6N66_RS17985	COG1530	ribonuclease E activity
G6N66_RS17990	COG0105	UTP biosynthetic process
G6N66_RS18000	COG0285	dihydrofolate synthase activity
G6N66_RS18020	COG3268	Saccharopine dehydrogenase
G6N66_RS18025	COG1388	LysM domain
G6N66_RS18035	COG0746	molybdenum cofactor guanylyltransferase activity
G6N66_RS18040	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N66_RS18045	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N66_RS18045	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N66_RS18050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N66_RS18055	COG2040	homocysteine
G6N66_RS18060	COG0740	serine-type endopeptidase activity
G6N66_RS18065	COG0740	serine-type endopeptidase activity
G6N66_RS18100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N66_RS18130	COG2346	COG2346, Truncated hemoglobins
G6N66_RS18135	COG0366	Alpha amylase catalytic
G6N66_RS18155	COG2902	Dehydrogenase
G6N66_RS18180	COG3830	Belongs to the UPF0237 family
G6N66_RS18180	COG0560	Phosphoserine phosphatase
G6N66_RS18200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G6N66_RS18215	COG3391	amine dehydrogenase activity
G6N66_RS18300	COG3177	Filamentation induced by cAMP protein fic
G6N66_RS18310	COG0277	FAD linked oxidase domain protein
G6N66_RS18340	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N66_RS18360	COG2030	dehydratase
G6N66_RS18365	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N66_RS18405	COG0300	oxidoreductase activity
G6N66_RS18410	COG0433	COG0433 Predicted ATPase
G6N66_RS18415	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G6N66_RS18430	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS18435	COG4552	Acetyltransferase involved in intracellular survival and related
G6N66_RS18480	COG2197	response regulator
G6N66_RS18495	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N66_RS18505	COG3757	hydrolase, family 25
G6N66_RS18510	COG4638	Rieske (2fe-2S)
G6N66_RS18545	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS18555	COG2124	cytochrome p450
G6N66_RS18585	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18590	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18595	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18600	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18635	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18640	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18675	COG2124	cytochrome p450
G6N66_RS18715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N66_RS18725	COG1309	transcriptional regulator
G6N66_RS18735	COG0714	Associated with various cellular activities
G6N66_RS18745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N66_RS18765	COG2072	flavoprotein involved in K transport
G6N66_RS18770	COG4638	Rieske (2fe-2S)
G6N66_RS18800	COG0183	Belongs to the thiolase family
G6N66_RS18810	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N66_RS18880	COG1024	Enoyl-CoA hydratase
G6N66_RS18885	COG1024	Enoyl-CoA hydratase
G6N66_RS18890	COG1024	Enoyl-CoA hydratase
G6N66_RS18910	COG1802	Transcriptional regulator
G6N66_RS18915	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS18925	COG0183	Belongs to the thiolase family
G6N66_RS18935	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS18985	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N66_RS18995	COG1234	tRNA 3'-trailer cleavage
G6N66_RS19000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6N66_RS19025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N66_RS19045	COG0058	SHG alpha-glucan phosphorylase activity
G6N66_RS19055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N66_RS19080	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N66_RS19095	COG2814	Major facilitator Superfamily
G6N66_RS19100	COG0583	DNA-binding transcription factor activity
G6N66_RS19140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N66_RS19175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N66_RS19175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N66_RS19185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N66_RS19190	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N66_RS19210	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N66_RS19225	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS19245	COG0460	homoserine dehydrogenase
G6N66_RS19250	COG0019	diaminopimelate decarboxylase activity
G6N66_RS19255	COG0018	arginyl-trna synthetase
G6N66_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS19305	COG1309	transcriptional regulator
G6N66_RS19325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS19420	COG1403	HNH endonuclease
G6N66_RS19495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS19515	COG0277	FAD linked oxidase domain protein
G6N66_RS19565	COG3391	amine dehydrogenase activity
G6N66_RS19575	COG3391	amine dehydrogenase activity
G6N66_RS19630	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N66_RS19630	COG0567	Dehydrogenase, E1 component
G6N66_RS19660	COG0039	L-malate dehydrogenase activity
G6N66_RS19665	COG0598	Magnesium transport protein CorA
G6N66_RS19705	COG2239	Acts as a magnesium transporter
G6N66_RS19725	COG2026	Addiction module toxin, RelE StbE family
G6N66_RS19730	COG2161	toxin-antitoxin pair type II binding
G6N66_RS19750	COG0463	Glycosyl transferase, family 2
G6N66_RS19840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N66_RS19845	COG5662	AntiSigma factor
G6N66_RS19870	COG1309	transcriptional regulator
G6N66_RS19875	COG1131	(ABC) transporter
G6N66_RS19880	COG3559	Exporter of polyketide antibiotics
G6N66_RS19890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N66_RS19895	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G6N66_RS19930	COG1216	Glycosyl transferase, family 2
G6N66_RS19935	COG1686	Belongs to the peptidase S11 family
G6N66_RS19980	COG0519	Catalyzes the synthesis of GMP from XMP
G6N66_RS19990	COG0463	Glycosyl transferase, family 2
G6N66_RS20000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N66_RS20005	COG1611	Belongs to the LOG family
G6N66_RS20020	COG3744	PilT protein domain protein
G6N66_RS20025	COG4118	positive regulation of growth
G6N66_RS20030	COG1487	ribonuclease activity
G6N66_RS20070	COG0477	Major facilitator Superfamily
G6N66_RS20075	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS20095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS20100	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS20105	COG2124	cytochrome p450
G6N66_RS20110	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS20125	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS20150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS20155	COG1024	Enoyl-CoA hydratase
G6N66_RS20165	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS20175	COG0506	proline dehydrogenase activity
G6N66_RS20180	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS20185	COG2508	Transcriptional regulator
G6N66_RS20185	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G6N66_RS20220	COG0531	amino acid
G6N66_RS20230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N66_RS20260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N66_RS20290	COG1140	nitrate reductase beta subunit
G6N66_RS20305	COG2070	2-Nitropropane dioxygenase
G6N66_RS20335	COG2267	carboxylic ester hydrolase activity
G6N66_RS20345	COG2072	flavoprotein involved in K transport
G6N66_RS20350	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N66_RS20360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS20405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS20460	COG3467	pyridoxamine 5'-phosphate
G6N66_RS20500	COG2409	Drug exporters of the RND superfamily
G6N66_RS20510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS20515	COG1024	Enoyl-CoA hydratase
G6N66_RS20520	COG0702	epimerase
G6N66_RS20530	COG0702	epimerase
G6N66_RS20555	COG1024	Enoyl-CoA hydratase
G6N66_RS20570	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS20575	COG2124	cytochrome p450
G6N66_RS20595	COG0714	Associated with various cellular activities
G6N66_RS20610	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS20615	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS20620	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS20630	COG1309	transcriptional regulator
G6N66_RS20640	COG0702	epimerase
G6N66_RS20670	COG1231	oxidoreductase activity
G6N66_RS20690	COG5651	PPE family
G6N66_RS20710	COG0574	Belongs to the PEP-utilizing enzyme family
G6N66_RS20710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N66_RS20725	COG0596	Alpha beta hydrolase
G6N66_RS20770	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N66_RS20790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N66_RS20840	COG2161	toxin-antitoxin pair type II binding
G6N66_RS20845	COG0012	GTP binding
G6N66_RS20855	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6N66_RS20860	COG1403	HNH endonuclease
G6N66_RS20925	COG3391	amine dehydrogenase activity
G6N66_RS20935	COG1570	exodeoxyribonuclease VII activity
G6N66_RS20950	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N66_RS20990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N66_RS21000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N66_RS21005	COG0572	uridine kinase
G6N66_RS21020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6N66_RS21030	COG1331	Highly conserved protein containing a thioredoxin domain
G6N66_RS21060	COG1714	RDD family
G6N66_RS21070	COG0657	acetylesterase activity
G6N66_RS21075	COG2755	lipolytic protein G-D-S-L family
G6N66_RS21080	COG0183	Belongs to the thiolase family
G6N66_RS21090	COG1024	Enoyl-CoA hydratase
G6N66_RS21155	COG0657	acetylesterase activity
G6N66_RS21215	COG5651	PPE family
G6N66_RS21225	COG4842	Belongs to the WXG100 family
G6N66_RS21240	COG0745	RESPONSE REGULATOR receiver
G6N66_RS21245	COG2205	protein histidine kinase activity
G6N66_RS21260	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N66_RS21265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6N66_RS21310	COG3956	TIGRFAM MazG family protein
G6N66_RS21375	COG0193	aminoacyl-tRNA hydrolase activity
G6N66_RS21390	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS21410	COG0084	hydrolase, TatD family'
G6N66_RS21455	COG1595	DNA-templated transcription, initiation
G6N66_RS21460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N66_RS21505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N66_RS21505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N66_RS21510	COG1309	transcriptional regulator
G6N66_RS21585	COG3668	Plasmid stabilization system
G6N66_RS21590	COG3609	addiction module antidote protein, CC2985 family
G6N66_RS21595	COG3550	peptidyl-serine autophosphorylation
G6N66_RS21630	COG4584	PFAM Integrase catalytic
G6N66_RS21670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N66_RS21675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N66_RS21690	COG1970	mechanosensitive ion channel activity
G6N66_RS21695	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N66_RS21695	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N66_RS21700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N66_RS21735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N66_RS21750	COG1024	Enoyl-CoA hydratase
G6N66_RS21815	COG0739	heme binding
G6N66_RS21855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N66_RS21900	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N66_RS21910	COG0277	FAD linked oxidase domain protein
G6N66_RS21940	COG4974	Belongs to the 'phage' integrase family
G6N66_RS21960	COG0246	Mannitol dehydrogenase
G6N66_RS21975	COG0581	inorganic phosphate transmembrane transporter activity
G6N66_RS22025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS22130	COG0688	phosphatidylethanolamine metabolic process
G6N66_RS22135	COG1309	transcriptional regulator
G6N66_RS22140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS22150	COG0438	transferase activity, transferring glycosyl groups
G6N66_RS22195	COG3903	Transcriptional regulator
G6N66_RS22195	COG3629	intracellular signal transduction
G6N66_RS22205	COG0259	pyridoxamine-phosphate oxidase activity
G6N66_RS22230	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N66_RS22250	COG1846	Transcriptional regulator
G6N66_RS22265	COG2814	Major facilitator Superfamily
G6N66_RS22280	COG0435	Glutathione S-transferase
G6N66_RS22290	COG1278	Cold shock
G6N66_RS22315	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N66_RS22335	COG1061	Type III restriction enzyme res subunit
G6N66_RS22340	COG0183	Belongs to the thiolase family
G6N66_RS22385	COG1024	Enoyl-CoA hydratase
G6N66_RS22385	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N66_RS22390	COG0183	Belongs to the thiolase family
G6N66_RS22415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS22425	COG3961	Belongs to the TPP enzyme family
G6N66_RS22440	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS22455	COG1024	Enoyl-CoA hydratase
G6N66_RS22500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS22525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS22530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS22540	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS22550	COG2124	cytochrome p450
G6N66_RS22570	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22575	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N66_RS22595	COG0778	Nitroreductase
G6N66_RS22595	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G6N66_RS22605	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS22615	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS22620	COG4638	Rieske (2fe-2S)
G6N66_RS22665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS22745	COG0714	Associated with various cellular activities
G6N66_RS22750	COG4584	PFAM Integrase catalytic
G6N66_RS22785	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS22790	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS22795	COG0657	acetylesterase activity
G6N66_RS22835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N66_RS22845	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22880	COG2124	cytochrome p450
G6N66_RS22910	COG1309	transcriptional regulator
G6N66_RS22915	COG0183	Belongs to the thiolase family
G6N66_RS22920	COG1024	Enoyl-CoA hydratase
G6N66_RS22940	COG4638	Rieske (2fe-2S)
G6N66_RS22950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N66_RS22960	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22965	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22975	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS22990	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS23000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS23005	COG1024	Enoyl-CoA hydratase
G6N66_RS23010	COG0006	proline dipeptidase activity
G6N66_RS23050	COG2132	Multicopper oxidase
G6N66_RS23065	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS23080	COG3384	dioxygenase
G6N66_RS23085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS23100	COG1053	succinate dehydrogenase
G6N66_RS23115	COG0596	Alpha beta hydrolase
G6N66_RS23145	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS23150	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS23160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N66_RS23170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS23175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS23180	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N66_RS23185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N66_RS23185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N66_RS23280	COG1609	Transcriptional regulator
G6N66_RS23300	COG4974	Belongs to the 'phage' integrase family
G6N66_RS23320	COG0583	DNA-binding transcription factor activity
G6N66_RS23350	COG0640	Transcriptional regulator
G6N66_RS23380	COG0704	Plays a role in the regulation of phosphate uptake
G6N66_RS23385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N66_RS23410	COG0745	RESPONSE REGULATOR receiver
G6N66_RS23440	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N66_RS23480	COG0243	molybdopterin cofactor binding
G6N66_RS23520	COG1362	aminopeptidase activity
G6N66_RS23525	COG2837	iron assimilation
G6N66_RS23535	COG2258	MOSC domain
G6N66_RS23565	COG3548	integral membrane protein
G6N66_RS23585	COG2188	Transcriptional regulator
G6N66_RS23600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N66_RS23615	COG0477	Major facilitator Superfamily
G6N66_RS23625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6N66_RS23650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N66_RS23710	COG4221	oxidoreductase activity
G6N66_RS23715	COG2124	cytochrome p450
G6N66_RS23755	COG5002	protein histidine kinase activity
G6N66_RS23755	COG5000	phosphorelay sensor kinase activity
G6N66_RS23760	COG0745	RESPONSE REGULATOR receiver
G6N66_RS23785	COG1136	(ABC) transporter
G6N66_RS23805	COG0406	alpha-ribazole phosphatase activity
G6N66_RS23840	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS23865	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS23870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N66_RS23910	COG1316	TRANSCRIPTIONal
G6N66_RS23920	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS23925	COG1024	Enoyl-CoA hydratase
G6N66_RS23960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS23985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS23990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS23995	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS24005	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24010	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24015	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS24025	COG0028	Belongs to the TPP enzyme family
G6N66_RS24045	COG1024	Enoyl-CoA hydratase
G6N66_RS24055	COG2124	cytochrome p450
G6N66_RS24065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS24105	COG4638	Rieske (2fe-2S)
G6N66_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS24145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N66_RS24150	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N66_RS24155	COG3971	2-oxopent-4-enoate hydratase activity
G6N66_RS24165	COG2030	dehydratase
G6N66_RS24180	COG2030	dehydratase
G6N66_RS24185	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24190	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24195	COG2124	cytochrome p450
G6N66_RS24200	COG0183	Belongs to the thiolase family
G6N66_RS24215	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS24220	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS24225	COG1024	Enoyl-CoA hydratase
G6N66_RS24245	COG0183	Belongs to the thiolase family
G6N66_RS24260	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS24265	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24270	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS24275	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24280	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24285	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24365	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS24370	COG1309	transcriptional regulator
G6N66_RS24375	COG1609	Transcriptional regulator
G6N66_RS24385	COG1121	(ABC) transporter
G6N66_RS24390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6N66_RS24445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N66_RS24490	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G6N66_RS24490	COG3261	NADH dehydrogenase
G6N66_RS24495	COG0651	ATP synthesis coupled electron transport
G6N66_RS24505	COG0650	Formate hydrogenlyase subunit 4
G6N66_RS24515	COG3260	NADH ubiquinone oxidoreductase 20
G6N66_RS24590	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6N66_RS24595	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N66_RS24620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G6N66_RS24630	COG0302	gtp cyclohydrolase
G6N66_RS24635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N66_RS24645	COG2267	carboxylic ester hydrolase activity
G6N66_RS24655	COG1063	alcohol dehydrogenase
G6N66_RS24675	COG0037	tRNA processing
G6N66_RS24685	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N66_RS24730	COG0470	DNA polymerase III
G6N66_RS24755	COG1205	dead DEAH box helicase
G6N66_RS24755	COG1111	helicase
G6N66_RS24815	COG4172	Belongs to the ABC transporter superfamily
G6N66_RS24820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N66_RS24825	COG0601	transmembrane transport
G6N66_RS24875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N66_RS24895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N66_RS24900	COG0251	oxidation-reduction process
G6N66_RS24925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N66_RS24930	COG1408	metallophosphoesterase
G6N66_RS24935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N66_RS24970	COG1309	transcriptional regulator
G6N66_RS24985	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N66_RS24990	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N66_RS24995	COG2172	sigma factor antagonist activity
G6N66_RS25020	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N66_RS25025	COG0693	protein deglycase activity
G6N66_RS25030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS25055	COG0714	Associated with various cellular activities
G6N66_RS25075	COG5651	PPE family
G6N66_RS25080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N66_RS25080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G6N66_RS25085	COG1136	(ABC) transporter
G6N66_RS25100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N66_RS25105	COG0028	Belongs to the TPP enzyme family
G6N66_RS25125	COG1695	Transcriptional regulator
G6N66_RS25130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N66_RS25145	COG3391	amine dehydrogenase activity
G6N66_RS25150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N66_RS25160	COG0121	glutamine amidotransferase
G6N66_RS25165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N66_RS25225	COG0346	lactoylglutathione lyase activity
G6N66_RS25250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N66_RS25275	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N66_RS25290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N66_RS25295	COG1309	transcriptional regulator
G6N66_RS25305	COG1063	alcohol dehydrogenase
G6N66_RS25315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N66_RS25390	COG3237	CsbD-like
G6N66_RS25405	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS25430	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS25445	COG4638	Rieske (2fe-2S)
G6N66_RS25465	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS25480	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS25515	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N66_RS25555	COG1793	dna ligase
G6N66_RS25570	COG2124	cytochrome p450
G6N66_RS25595	COG3804	dihydrodipicolinate reductase
G6N66_RS25620	COG2301	Belongs to the HpcH HpaI aldolase family
G6N66_RS25625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N66_RS25675	COG0393	Putative heavy-metal-binding
G6N66_RS25720	COG0758	DNA mediated transformation
G6N66_RS25730	COG0590	tRNA wobble adenosine to inosine editing
G6N66_RS25740	COG0287	Prephenate dehydrogenase
G6N66_RS25755	COG1174	glycine betaine transport
G6N66_RS25760	COG0517	IMP dehydrogenase activity
G6N66_RS25760	COG1125	glycine betaine transport
G6N66_RS25770	COG5416	Lipopolysaccharide assembly protein A domain
G6N66_RS25795	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS25820	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N66_RS25830	COG2205	protein histidine kinase activity
G6N66_RS25835	COG0745	RESPONSE REGULATOR receiver
G6N66_RS25850	COG0739	heme binding
G6N66_RS25875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6N66_RS25885	COG3654	unkown
G6N66_RS25925	COG1404	Belongs to the peptidase S8 family
G6N66_RS25980	COG0070	glutamate synthase
G6N66_RS25980	COG0067	glutamate synthase
G6N66_RS25980	COG0069	glutamate synthase activity
G6N66_RS26000	COG1796	DNA polymerase
G6N66_RS26000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N66_RS26010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6N66_RS26015	COG1309	transcriptional regulator
G6N66_RS26075	COG1316	TRANSCRIPTIONal
G6N66_RS26110	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6N66_RS26130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N66_RS26145	COG1233	COG1233 Phytoene dehydrogenase and related
G6N66_RS26160	COG3321	synthase
G6N66_RS26160	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS26160	COG0604	alcohol dehydrogenase
G6N66_RS26175	COG5651	PPE family
G6N66_RS26215	COG0561	phosphatase activity
G6N66_RS26225	COG0754	glutathionylspermidine amidase activity
G6N66_RS26230	COG3766	membrane
G6N66_RS26255	COG1216	Glycosyl transferase, family 2
G6N66_RS26270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N66_RS26290	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS26300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N66_RS26315	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS26375	COG0277	FAD linked oxidase domain protein
G6N66_RS26420	COG0604	alcohol dehydrogenase
G6N66_RS26480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS26515	COG0741	lytic transglycosylase activity
G6N66_RS26515	COG0791	NLP P60 protein
G6N66_RS26530	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS26550	COG1716	ATPase activity
G6N66_RS26575	COG0515	serine threonine protein kinase
G6N66_RS26580	COG2815	serine threonine protein kinase
G6N66_RS26580	COG0515	serine threonine protein kinase
G6N66_RS26605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6N66_RS26615	COG5651	PPE family
G6N66_RS26615	COG0657	acetylesterase activity
G6N66_RS26635	COG1372	Participates in initiation and elongation during chromosome replication
G6N66_RS26635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N66_RS26640	COG0187	DNA topoisomerase II activity
G6N66_RS26645	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N66_RS26650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N66_RS26655	COG0592	DNA-directed DNA polymerase activity
G6N66_RS26660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N66_RS26670	COG0594	ribonuclease P activity
G6N66_RS26675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N66_RS26680	COG0706	membrane insertase activity
G6N66_RS26690	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N66_RS26695	COG1192	Involved in chromosome partitioning
G6N66_RS26710	COG3409	Peptidoglycan-binding domain 1 protein
G6N66_RS26710	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N66_RS26805	COG1674	ftsk spoiiie
G6N66_RS26860	COG0765	amino acid transport
G6N66_RS26870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS26875	COG0596	Alpha beta hydrolase
G6N66_RS26895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N66_RS26910	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N66_RS26935	COG0305	Participates in initiation and elongation during chromosome replication
G6N66_RS26945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS26970	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS26980	COG2814	Major facilitator Superfamily
G6N66_RS27000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6N66_RS27060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS27080	COG1070	Carbohydrate kinase
G6N66_RS27085	COG1609	Transcriptional regulator
G6N66_RS27095	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27110	COG1116	anion transmembrane transporter activity
G6N66_RS27115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N66_RS27120	COG1116	anion transmembrane transporter activity
G6N66_RS27130	COG1116	anion transmembrane transporter activity
G6N66_RS27140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6N66_RS27145	COG3588	fructose-bisphosphate aldolase
G6N66_RS27150	COG3383	formate dehydrogenase (NAD+) activity
G6N66_RS27150	COG0243	molybdopterin cofactor binding
G6N66_RS27160	COG0437	4 iron, 4 sulfur cluster binding
G6N66_RS27170	COG0709	Synthesizes selenophosphate from selenide and ATP
G6N66_RS27190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS27195	COG2205	protein histidine kinase activity
G6N66_RS27205	COG1872	DUF167
G6N66_RS27215	COG1309	transcriptional regulator
G6N66_RS27220	COG0300	oxidoreductase activity
G6N66_RS27225	COG4552	Acetyltransferase involved in intracellular survival and related
G6N66_RS27230	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS27240	COG1733	regulation of RNA biosynthetic process
G6N66_RS27245	COG0604	alcohol dehydrogenase
G6N66_RS27260	COG0667	Aldo Keto reductase
G6N66_RS27275	COG4638	Rieske (2fe-2S)
G6N66_RS27315	COG0753	catalase activity
G6N66_RS27380	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS27405	COG1309	transcriptional regulator
G6N66_RS27410	COG1309	transcriptional regulator
G6N66_RS27415	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS27455	COG1309	transcriptional regulator
G6N66_RS27480	COG0222	ribosome binding
G6N66_RS27485	COG3327	negative regulation of DNA-templated transcription, initiation
G6N66_RS27495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS27510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N66_RS27515	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27560	COG2072	flavoprotein involved in K transport
G6N66_RS27565	COG2072	flavoprotein involved in K transport
G6N66_RS27570	COG0789	Transcriptional regulator
G6N66_RS27595	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27615	COG1063	alcohol dehydrogenase
G6N66_RS27645	COG2072	flavoprotein involved in K transport
G6N66_RS27655	COG0346	lactoylglutathione lyase activity
G6N66_RS27680	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27685	COG1053	succinate dehydrogenase
G6N66_RS27715	COG4221	oxidoreductase activity
G6N66_RS27720	COG2226	methyltransferase
G6N66_RS27725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N66_RS27730	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6N66_RS27765	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N66_RS27785	COG3800	Transcriptional regulator
G6N66_RS27785	COG1396	sequence-specific DNA binding
G6N66_RS27795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N66_RS27805	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N66_RS27850	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS27860	COG0604	alcohol dehydrogenase
G6N66_RS27870	COG0028	Belongs to the TPP enzyme family
G6N66_RS27880	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27885	COG2072	flavoprotein involved in K transport
G6N66_RS27895	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27910	COG0318	PFAM AMP-dependent synthetase and ligase
G6N66_RS27915	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27940	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS27945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N66_RS27945	COG2755	lipolytic protein G-D-S-L family
G6N66_RS27965	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS27965	COG3321	synthase
G6N66_RS27965	COG0604	alcohol dehydrogenase
G6N66_RS27975	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS27985	COG0028	Belongs to the TPP enzyme family
G6N66_RS28010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N66_RS28040	COG0842	Transport permease protein
G6N66_RS28040	COG1129	ABC transporter
G6N66_RS28085	COG1309	transcriptional regulator
G6N66_RS28105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS28150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N66_RS28185	COG0783	Belongs to the Dps family
G6N66_RS28190	COG1309	transcriptional regulator
G6N66_RS28195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS28205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N66_RS28210	COG1012	belongs to the aldehyde dehydrogenase family
G6N66_RS28215	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS28220	COG0604	alcohol dehydrogenase
G6N66_RS28220	COG1028	Short-chain dehydrogenase reductase Sdr
G6N66_RS28220	COG3321	synthase
G6N66_RS28245	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS28275	COG1309	transcriptional regulator
G6N66_RS28280	COG5651	PPE family
G6N66_RS28280	COG0657	acetylesterase activity
G6N66_RS28295	COG0277	FAD linked oxidase domain protein
G6N66_RS28330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N66_RS28335	COG1960	acyl-CoA dehydrogenase activity
G6N66_RS28350	COG5001	Diguanylate cyclase
G6N66_RS28420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS28425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N66_RS28450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N66_RS28480	COG3619	membrane
G6N66_RS28530	COG0583	DNA-binding transcription factor activity
G6N66_RS28550	COG2267	carboxylic ester hydrolase activity
G6N66_RS28570	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N66_RS28585	COG4122	O-methyltransferase activity
G6N66_RS28595	COG0129	dihydroxy-acid dehydratase activity
G6N66_RS28600	COG1937	Protein conserved in bacteria
G6N66_RS28605	COG2814	Major facilitator Superfamily
G6N66_RS28610	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS28615	COG1376	ErfK ybiS ycfS ynhG family protein
G6N66_RS28625	COG0243	molybdopterin cofactor binding
G6N66_RS28635	COG3590	peptidase
G6N66_RS28685	COG2409	Drug exporters of the RND superfamily
G6N66_RS28710	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G6N66_RS28725	COG1024	Enoyl-CoA hydratase