locus-tag	class	description
G6N27_RS00015	COG3599	regulation of cell shape
G6N27_RS00040	COG1254	Belongs to the acylphosphatase family
G6N27_RS00070	COG2267	carboxylic ester hydrolase activity
G6N27_RS00110	COG1686	Belongs to the peptidase S11 family
G6N27_RS00130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N27_RS00150	COG0681	Belongs to the peptidase S26 family
G6N27_RS00155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6N27_RS00170	COG0531	amino acid
G6N27_RS00175	COG0531	amino acid
G6N27_RS00235	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N27_RS00245	COG0154	amidase activity
G6N27_RS00280	COG0528	UMP kinase activity
G6N27_RS00295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N27_RS00305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N27_RS00315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G6N27_RS00345	COG1492	cobalamin metabolic process
G6N27_RS00360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N27_RS00365	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS00380	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N27_RS00410	COG0309	Hydrogenase expression formation protein (HypE)
G6N27_RS00415	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G6N27_RS00425	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G6N27_RS00430	COG0298	carbon dioxide binding
G6N27_RS00475	COG0375	protein maturation
G6N27_RS00510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N27_RS00510	COG1648	precorrin-2 dehydrogenase activity
G6N27_RS00520	COG0442	prolyl-tRNA aminoacylation
G6N27_RS00535	COG0779	Required for maturation of 30S ribosomal subunits
G6N27_RS00540	COG0195	Participates in both transcription termination and antitermination
G6N27_RS00555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6N27_RS00560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N27_RS00575	COG1024	Enoyl-CoA hydratase
G6N27_RS00625	COG0183	Belongs to the thiolase family
G6N27_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS00645	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS00655	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS00675	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N27_RS00695	COG0686	Belongs to the AlaDH PNT family
G6N27_RS00765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N27_RS00780	COG3119	arylsulfatase activity
G6N27_RS00790	COG4770	biotin carboxylase activity
G6N27_RS00810	COG0657	acetylesterase activity
G6N27_RS00820	COG1595	DNA-templated transcription, initiation
G6N27_RS00830	COG2201	protein-glutamate methylesterase activity
G6N27_RS00835	COG2197	response regulator
G6N27_RS00840	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS00845	COG3961	Belongs to the TPP enzyme family
G6N27_RS00860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS00870	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N27_RS00875	COG0300	oxidoreductase activity
G6N27_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS00885	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS00890	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS00895	COG0667	Aldo Keto reductase
G6N27_RS00930	COG3214	Protein conserved in bacteria
G6N27_RS00955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS01010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N27_RS01020	COG1058	Belongs to the CinA family
G6N27_RS01020	COG1546	Belongs to the CinA family
G6N27_RS01045	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N27_RS01070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N27_RS01080	COG1196	nuclear chromosome segregation
G6N27_RS01120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N27_RS01140	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS01155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N27_RS01160	COG1388	LysM domain
G6N27_RS01165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6N27_RS01255	COG0483	inositol monophosphate 1-phosphatase activity
G6N27_RS01275	COG0756	dUTP diphosphatase activity
G6N27_RS01305	COG0569	domain protein
G6N27_RS01310	COG0531	amino acid
G6N27_RS01315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N27_RS01320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G6N27_RS01365	COG1024	Enoyl-CoA hydratase
G6N27_RS01395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N27_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS01550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N27_RS01565	COG2070	2-Nitropropane dioxygenase
G6N27_RS01575	COG0667	Aldo Keto reductase
G6N27_RS01585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6N27_RS01605	COG0438	transferase activity, transferring glycosyl groups
G6N27_RS01620	COG1946	Acyl-CoA thioesterase
G6N27_RS01640	COG0110	maltose O-acetyltransferase activity
G6N27_RS01660	COG3766	membrane
G6N27_RS01695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6N27_RS01720	COG1396	sequence-specific DNA binding
G6N27_RS01730	COG0632	four-way junction helicase activity
G6N27_RS01735	COG2255	four-way junction helicase activity
G6N27_RS01750	COG1022	Amp-dependent synthetase and ligase
G6N27_RS01750	COG3320	Male sterility
G6N27_RS01780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N27_RS01785	COG0747	negative chemotaxis
G6N27_RS01790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6N27_RS01795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N27_RS01800	COG1088	dTDP-glucose 4,6-dehydratase activity
G6N27_RS01820	COG0124	histidyl-tRNA synthetase
G6N27_RS01825	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS01835	COG3391	amine dehydrogenase activity
G6N27_RS01870	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N27_RS01875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N27_RS01900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6N27_RS01910	COG1652	LysM domain
G6N27_RS01950	COG5473	translation initiation factor activity
G6N27_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS02005	COG2301	Belongs to the HpcH HpaI aldolase family
G6N27_RS02035	COG0432	Pfam Uncharacterised protein family UPF0047
G6N27_RS02040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N27_RS02050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6N27_RS02055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N27_RS02090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N27_RS02105	COG0006	proline dipeptidase activity
G6N27_RS02140	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N27_RS02160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G6N27_RS02165	COG0540	Belongs to the ATCase OTCase family
G6N27_RS02180	COG0505	Belongs to the CarA family
G6N27_RS02190	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N27_RS02200	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G6N27_RS02215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N27_RS02225	COG2072	flavoprotein involved in K transport
G6N27_RS02310	COG2020	methyltransferase activity
G6N27_RS02320	COG1714	RDD family
G6N27_RS02370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N27_RS02370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N27_RS02375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6N27_RS02385	COG1403	HNH endonuclease
G6N27_RS02390	COG0322	excinuclease ABC activity
G6N27_RS02405	COG1481	regulation of sporulation
G6N27_RS02415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6N27_RS02435	COG0657	acetylesterase activity
G6N27_RS02475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N27_RS02510	COG5651	PPE family
G6N27_RS02550	COG1131	(ABC) transporter
G6N27_RS02580	COG0396	ATPase activity
G6N27_RS02585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N27_RS02590	COG0822	iron-sulfur transferase activity
G6N27_RS02595	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N27_RS02605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N27_RS02625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N27_RS02635	COG0488	(ABC) transporter
G6N27_RS02645	COG1309	transcriptional regulator
G6N27_RS02650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N27_RS02660	COG0791	NLP P60 protein
G6N27_RS02660	COG3883	PFAM NLP P60 protein
G6N27_RS02675	COG0714	Associated with various cellular activities
G6N27_RS02685	COG2304	oxidoreductase activity
G6N27_RS02695	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6N27_RS02725	COG0477	Major facilitator Superfamily
G6N27_RS02780	COG2070	2-Nitropropane dioxygenase
G6N27_RS02810	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N27_RS02825	COG0252	asparaginase activity
G6N27_RS02830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6N27_RS02855	COG2346	COG2346, Truncated hemoglobins
G6N27_RS02865	COG0300	oxidoreductase activity
G6N27_RS02885	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS02955	COG0156	8-amino-7-oxononanoate synthase activity
G6N27_RS02980	COG0028	Belongs to the TPP enzyme family
G6N27_RS03045	COG1309	transcriptional regulator
G6N27_RS03050	COG1063	alcohol dehydrogenase
G6N27_RS03075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6N27_RS03080	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N27_RS03085	COG0483	inositol monophosphate 1-phosphatase activity
G6N27_RS03090	COG0107	imidazoleglycerol-phosphate synthase activity
G6N27_RS03095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N27_RS03115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N27_RS03155	COG1946	Acyl-CoA thioesterase
G6N27_RS03165	COG4988	ABC transporter
G6N27_RS03170	COG4988	ABC transporter
G6N27_RS03175	COG1294	oxidase, subunit
G6N27_RS03180	COG1271	oxidase subunit
G6N27_RS03235	COG0237	dephospho-CoA kinase activity
G6N27_RS03235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N27_RS03240	COG1733	regulation of RNA biosynthetic process
G6N27_RS03250	COG2197	response regulator
G6N27_RS03270	COG0842	Transport permease protein
G6N27_RS03270	COG1716	ATPase activity
G6N27_RS03270	COG1131	(ABC) transporter
G6N27_RS03315	COG0443	Heat shock 70 kDa protein
G6N27_RS03325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N27_RS03370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N27_RS03405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N27_RS03410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N27_RS03410	COG0072	phenylalanine-tRNA ligase activity
G6N27_RS03420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N27_RS03425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6N27_RS03435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N27_RS03445	COG0137	argininosuccinate synthase activity
G6N27_RS03450	COG0165	Argininosuccinate lyase
G6N27_RS03460	COG0488	(ABC) transporter
G6N27_RS03470	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N27_RS03485	COG1131	(ABC) transporter
G6N27_RS03495	COG2188	Transcriptional regulator
G6N27_RS03500	COG2094	Belongs to the DNA glycosylase MPG family
G6N27_RS03530	COG0647	UMP catabolic process
G6N27_RS03545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6N27_RS03565	COG0504	CTP synthase activity
G6N27_RS03590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6N27_RS03595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N27_RS03610	COG1160	GTP binding
G6N27_RS03625	COG2130	NADP-dependent
G6N27_RS03760	COG2197	response regulator
G6N27_RS03795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N27_RS03800	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS03830	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS03835	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS03840	COG1024	Enoyl-CoA hydratase
G6N27_RS03850	COG2197	response regulator
G6N27_RS03865	COG1024	Enoyl-CoA hydratase
G6N27_RS03875	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS03880	COG3971	2-oxopent-4-enoate hydratase activity
G6N27_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS03920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS03925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS03950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS04005	COG1024	Enoyl-CoA hydratase
G6N27_RS04015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N27_RS04020	COG0427	acetyl-CoA hydrolase
G6N27_RS04025	COG0183	Belongs to the thiolase family
G6N27_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS04040	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS04055	COG1845	cytochrome c oxidase, subunit III
G6N27_RS04080	COG0475	glutathione-regulated potassium exporter activity
G6N27_RS04135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS04145	COG2358	TRAP transporter, solute receptor (TAXI family
G6N27_RS04150	COG0656	L-ascorbic acid biosynthetic process
G6N27_RS04160	COG1033	growth of symbiont in host cell
G6N27_RS04160	COG2409	Drug exporters of the RND superfamily
G6N27_RS04175	COG2271	Major facilitator Superfamily
G6N27_RS04190	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS04290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS04330	COG5651	PPE family
G6N27_RS04375	COG1404	Belongs to the peptidase S8 family
G6N27_RS04535	COG1253	flavin adenine dinucleotide binding
G6N27_RS04550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N27_RS04590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS04625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS04630	COG0183	Belongs to the thiolase family
G6N27_RS04680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N27_RS04690	COG1309	transcriptional regulator
G6N27_RS04720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N27_RS04730	COG0583	DNA-binding transcription factor activity
G6N27_RS04745	COG1024	Enoyl-CoA hydratase
G6N27_RS04770	COG0174	glutamine synthetase
G6N27_RS04830	COG0412	Dienelactone hydrolase
G6N27_RS04835	COG1946	Acyl-CoA thioesterase
G6N27_RS04855	COG1716	ATPase activity
G6N27_RS04875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS04880	COG2353	YceI-like domain
G6N27_RS04905	COG2070	2-Nitropropane dioxygenase
G6N27_RS04920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS04925	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS04930	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS04935	COG2030	dehydratase
G6N27_RS04955	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS04975	COG1546	Belongs to the CinA family
G6N27_RS04975	COG1058	Belongs to the CinA family
G6N27_RS04980	COG2814	Major facilitator Superfamily
G6N27_RS04995	COG1716	ATPase activity
G6N27_RS05000	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS05035	COG1942	4-Oxalocrotonate Tautomerase
G6N27_RS05045	COG2755	lipolytic protein G-D-S-L family
G6N27_RS05065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS05145	COG0596	Alpha beta hydrolase
G6N27_RS05155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS05160	COG3757	hydrolase, family 25
G6N27_RS05175	COG2208	phosphoserine phosphatase activity
G6N27_RS05175	COG2770	Histidine kinase
G6N27_RS05180	COG0596	Alpha beta hydrolase
G6N27_RS05200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6N27_RS05205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS05230	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N27_RS05280	COG1846	Transcriptional regulator
G6N27_RS05310	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N27_RS05320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS05340	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G6N27_RS05380	COG3842	ATPase activity
G6N27_RS05385	COG0395	ABC-type sugar transport system, permease component
G6N27_RS05390	COG1175	transmembrane transport
G6N27_RS05395	COG2182	Extracellular solute-binding protein
G6N27_RS05405	COG1335	isochorismatase
G6N27_RS05410	COG0438	transferase activity, transferring glycosyl groups
G6N27_RS05415	COG2226	methyltransferase
G6N27_RS05450	COG3265	gluconokinase activity
G6N27_RS05460	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N27_RS05470	COG0604	alcohol dehydrogenase
G6N27_RS05470	COG3321	synthase
G6N27_RS05515	COG0300	oxidoreductase activity
G6N27_RS05525	COG0300	oxidoreductase activity
G6N27_RS05535	COG0469	pyruvate kinase activity
G6N27_RS05570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N27_RS05595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N27_RS05605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N27_RS05610	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N27_RS05660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N27_RS05670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6N27_RS05680	COG0477	Major facilitator Superfamily
G6N27_RS05685	COG1410	methionine synthase
G6N27_RS05685	COG0646	methionine synthase
G6N27_RS05695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N27_RS05710	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N27_RS05735	COG1968	undecaprenyl-diphosphatase activity
G6N27_RS05755	COG0167	dihydroorotate dehydrogenase activity
G6N27_RS05765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N27_RS05810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6N27_RS05825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N27_RS05870	COG0768	penicillin binding
G6N27_RS05930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N27_RS05960	COG0003	Pfam Anion-transporting ATPase
G6N27_RS06055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N27_RS06085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6N27_RS06100	COG1305	Transglutaminase-like
G6N27_RS06110	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS06130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6N27_RS06135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6N27_RS06145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N27_RS06170	COG0321	lipoyl(octanoyl) transferase activity
G6N27_RS06175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6N27_RS06200	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS06205	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS06215	COG1231	oxidoreductase activity
G6N27_RS06230	COG0596	Alpha beta hydrolase
G6N27_RS06235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS06295	COG0697	spore germination
G6N27_RS06335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G6N27_RS06420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N27_RS06425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6N27_RS06440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS06515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N27_RS06520	COG3038	cytochrome b561
G6N27_RS06525	COG0753	catalase activity
G6N27_RS06545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N27_RS06565	COG0438	transferase activity, transferring glycosyl groups
G6N27_RS06590	COG1305	Transglutaminase-like
G6N27_RS06655	COG1024	Enoyl-CoA hydratase
G6N27_RS06670	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N27_RS06675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N27_RS06675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N27_RS06680	COG1073	alpha beta
G6N27_RS06725	COG1063	alcohol dehydrogenase
G6N27_RS06765	COG1595	DNA-templated transcription, initiation
G6N27_RS06800	COG0395	ABC-type sugar transport system, permease component
G6N27_RS06825	COG1131	(ABC) transporter
G6N27_RS06825	COG1716	ATPase activity
G6N27_RS06825	COG0842	Transport permease protein
G6N27_RS06830	COG1192	Involved in chromosome partitioning
G6N27_RS06885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS06910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS06915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS06920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N27_RS06925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N27_RS06940	COG1045	serine acetyltransferase
G6N27_RS06945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N27_RS06950	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G6N27_RS06955	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G6N27_RS06960	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6N27_RS06960	COG0235	Class ii aldolase
G6N27_RS07000	COG0423	glycine-tRNA ligase activity
G6N27_RS07060	COG0484	heat shock protein binding
G6N27_RS07065	COG1420	regulation of RNA biosynthetic process
G6N27_RS07095	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G6N27_RS07105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS07125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS07135	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N27_RS07180	COG1169	isochorismate synthase
G6N27_RS07225	COG4208	sulfate ABC transporter
G6N27_RS07235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N27_RS07245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS07285	COG0617	tRNA 3'-terminal CCA addition
G6N27_RS07285	COG0517	IMP dehydrogenase activity
G6N27_RS07285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N27_RS07295	COG1305	Transglutaminase-like
G6N27_RS07325	COG1596	polysaccharide export
G6N27_RS07325	COG1555	photosystem II stabilization
G6N27_RS07330	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS07335	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS07355	COG5651	PPE family
G6N27_RS07360	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS07390	COG3321	synthase
G6N27_RS07390	COG0604	alcohol dehydrogenase
G6N27_RS07405	COG2755	lipolytic protein G-D-S-L family
G6N27_RS07415	COG0799	negative regulation of ribosome biogenesis
G6N27_RS07420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N27_RS07430	COG0542	response to heat
G6N27_RS07445	COG0668	transmembrane transport
G6N27_RS07450	COG5002	protein histidine kinase activity
G6N27_RS07455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N27_RS07480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N27_RS07535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6N27_RS07540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N27_RS07555	COG1530	ribonuclease E activity
G6N27_RS07560	COG0105	UTP biosynthetic process
G6N27_RS07570	COG0285	dihydrofolate synthase activity
G6N27_RS07575	COG0525	valine-tRNA ligase activity
G6N27_RS07585	COG3268	Saccharopine dehydrogenase
G6N27_RS07590	COG0823	Involved in the tonB-independent uptake of proteins
G6N27_RS07590	COG1506	peptidase
G6N27_RS07590	COG4946	Tricorn protease homolog
G6N27_RS07595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6N27_RS07595	COG2124	cytochrome p450
G6N27_RS07600	COG2030	dehydratase
G6N27_RS07605	COG1388	LysM domain
G6N27_RS07610	COG0746	molybdenum cofactor guanylyltransferase activity
G6N27_RS07615	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N27_RS07620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N27_RS07620	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N27_RS07630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N27_RS07635	COG2040	homocysteine
G6N27_RS07640	COG0740	serine-type endopeptidase activity
G6N27_RS07685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N27_RS07715	COG0366	Alpha amylase catalytic
G6N27_RS07735	COG2902	Dehydrogenase
G6N27_RS07755	COG5651	PPE family
G6N27_RS07755	COG0657	acetylesterase activity
G6N27_RS07790	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N27_RS07815	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS07825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N27_RS07845	COG0300	oxidoreductase activity
G6N27_RS07850	COG0433	COG0433 Predicted ATPase
G6N27_RS07870	COG1376	ErfK ybiS ycfS ynhG family protein
G6N27_RS07940	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N27_RS07995	COG4638	Rieske (2fe-2S)
G6N27_RS08000	COG2124	cytochrome p450
G6N27_RS08015	COG1802	Transcriptional regulator
G6N27_RS08030	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08035	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08040	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08045	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08055	COG0657	acetylesterase activity
G6N27_RS08065	COG2814	Major facilitator Superfamily
G6N27_RS08085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N27_RS08100	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS08105	COG1024	Enoyl-CoA hydratase
G6N27_RS08115	COG0022	dehydrogenase e1 component
G6N27_RS08120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N27_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS08140	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08145	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08195	COG1403	HNH endonuclease
G6N27_RS08220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N27_RS08240	COG2072	flavoprotein involved in K transport
G6N27_RS08265	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS08275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N27_RS08280	COG0640	Transcriptional regulator
G6N27_RS08290	COG0798	PFAM Bile acid sodium symporter
G6N27_RS08295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N27_RS08315	COG0183	Belongs to the thiolase family
G6N27_RS08325	COG2124	cytochrome p450
G6N27_RS08330	COG0183	Belongs to the thiolase family
G6N27_RS08335	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08360	COG1024	Enoyl-CoA hydratase
G6N27_RS08370	COG1024	Enoyl-CoA hydratase
G6N27_RS08385	COG1024	Enoyl-CoA hydratase
G6N27_RS08390	COG1024	Enoyl-CoA hydratase
G6N27_RS08400	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS08420	COG1802	Transcriptional regulator
G6N27_RS08430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS08435	COG0183	Belongs to the thiolase family
G6N27_RS08445	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS08460	COG2072	flavoprotein involved in K transport
G6N27_RS08480	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08485	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS08490	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS08495	COG1309	transcriptional regulator
G6N27_RS08545	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N27_RS08550	COG1234	tRNA 3'-trailer cleavage
G6N27_RS08565	COG3191	aminopeptidase activity
G6N27_RS08580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N27_RS08590	COG0058	SHG alpha-glucan phosphorylase activity
G6N27_RS08600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N27_RS08615	COG0346	lactoylglutathione lyase activity
G6N27_RS08625	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N27_RS08635	COG1309	transcriptional regulator
G6N27_RS08680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N27_RS08700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6N27_RS08715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N27_RS08715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N27_RS08730	COG0356	it plays a direct role in the translocation of protons across the membrane
G6N27_RS08750	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N27_RS08755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N27_RS08765	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS08785	COG0460	homoserine dehydrogenase
G6N27_RS08790	COG0019	diaminopimelate decarboxylase activity
G6N27_RS08795	COG0018	arginyl-trna synthetase
G6N27_RS08840	COG2140	Oxalate decarboxylase
G6N27_RS08845	COG2140	Oxalate decarboxylase
G6N27_RS08870	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N27_RS08985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS08995	COG0277	FAD linked oxidase domain protein
G6N27_RS09025	COG0300	oxidoreductase activity
G6N27_RS09085	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N27_RS09085	COG0567	Dehydrogenase, E1 component
G6N27_RS09130	COG2124	cytochrome p450
G6N27_RS09140	COG4221	oxidoreductase activity
G6N27_RS09145	COG5651	PPE family
G6N27_RS09145	COG0657	acetylesterase activity
G6N27_RS09150	COG0300	oxidoreductase activity
G6N27_RS09185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS09220	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS09225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N27_RS09260	COG0281	malic enzyme
G6N27_RS09265	COG1403	HNH endonuclease
G6N27_RS09270	COG0039	L-malate dehydrogenase activity
G6N27_RS09275	COG0598	Magnesium transport protein CorA
G6N27_RS09325	COG2239	Acts as a magnesium transporter
G6N27_RS09350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N27_RS09355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N27_RS09370	COG4122	O-methyltransferase activity
G6N27_RS09375	COG1309	transcriptional regulator
G6N27_RS09380	COG1131	(ABC) transporter
G6N27_RS09385	COG3559	Exporter of polyketide antibiotics
G6N27_RS09395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6N27_RS09400	COG0297	glycogen (starch) synthase activity
G6N27_RS09410	COG0519	Catalyzes the synthesis of GMP from XMP
G6N27_RS09420	COG0463	Glycosyl transferase, family 2
G6N27_RS09425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N27_RS09430	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS09435	COG1611	Belongs to the LOG family
G6N27_RS09460	COG0477	Major facilitator Superfamily
G6N27_RS09465	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS09580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS09595	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS09610	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS09655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N27_RS09710	COG1022	Amp-dependent synthetase and ligase
G6N27_RS09735	COG0506	proline dehydrogenase activity
G6N27_RS09740	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS09750	COG4424	Sulfotransferase
G6N27_RS09780	COG0531	amino acid
G6N27_RS09785	COG0531	amino acid
G6N27_RS09790	COG0531	amino acid
G6N27_RS09805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N27_RS09815	COG1902	pentaerythritol trinitrate reductase activity
G6N27_RS09815	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N27_RS09820	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G6N27_RS09830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N27_RS09905	COG3467	pyridoxamine 5'-phosphate
G6N27_RS09925	COG2226	methyltransferase
G6N27_RS09935	COG2409	Drug exporters of the RND superfamily
G6N27_RS09945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS09950	COG1024	Enoyl-CoA hydratase
G6N27_RS09960	COG0702	epimerase
G6N27_RS09970	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6N27_RS09980	COG1024	Enoyl-CoA hydratase
G6N27_RS09985	COG0183	Belongs to the thiolase family
G6N27_RS10030	COG3804	dihydrodipicolinate reductase
G6N27_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS10045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N27_RS10055	COG1396	sequence-specific DNA binding
G6N27_RS10055	COG3800	Transcriptional regulator
G6N27_RS10065	COG0574	Belongs to the PEP-utilizing enzyme family
G6N27_RS10065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N27_RS10080	COG1403	HNH endonuclease
G6N27_RS10090	COG0596	Alpha beta hydrolase
G6N27_RS10115	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N27_RS10160	COG2072	flavoprotein involved in K transport
G6N27_RS10210	COG0012	GTP binding
G6N27_RS10230	COG1570	exodeoxyribonuclease VII activity
G6N27_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS10290	COG2271	Major facilitator Superfamily
G6N27_RS10295	COG0726	polysaccharide deacetylase
G6N27_RS10300	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N27_RS10345	COG3631	Ketosteroid isomerase-related protein
G6N27_RS10350	COG1331	Highly conserved protein containing a thioredoxin domain
G6N27_RS10385	COG1714	RDD family
G6N27_RS10395	COG0657	acetylesterase activity
G6N27_RS10400	COG2755	lipolytic protein G-D-S-L family
G6N27_RS10405	COG0183	Belongs to the thiolase family
G6N27_RS10420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N27_RS10480	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS10540	COG0745	RESPONSE REGULATOR receiver
G6N27_RS10545	COG2205	protein histidine kinase activity
G6N27_RS10560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N27_RS10565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6N27_RS10580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N27_RS10620	COG3956	TIGRFAM MazG family protein
G6N27_RS10685	COG0463	Glycosyl transferase, family 2
G6N27_RS10690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N27_RS10705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N27_RS10760	COG0463	Glycosyl transferase, family 2
G6N27_RS10835	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G6N27_RS10850	COG1309	transcriptional regulator
G6N27_RS10885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G6N27_RS10890	COG0193	aminoacyl-tRNA hydrolase activity
G6N27_RS10900	COG2207	Transcriptional regulator
G6N27_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS10930	COG0084	hydrolase, TatD family'
G6N27_RS10955	COG1252	NADH dehydrogenase
G6N27_RS10965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6N27_RS10985	COG3629	intracellular signal transduction
G6N27_RS10985	COG3903	Transcriptional regulator
G6N27_RS11030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N27_RS11030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N27_RS11035	COG2226	methyltransferase
G6N27_RS11050	COG2124	cytochrome p450
G6N27_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS11065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS11070	COG4221	oxidoreductase activity
G6N27_RS11100	COG4221	oxidoreductase activity
G6N27_RS11185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N27_RS11190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N27_RS11220	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N27_RS11220	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N27_RS11225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N27_RS11230	COG2205	protein histidine kinase activity
G6N27_RS11250	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS11255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N27_RS11270	COG1024	Enoyl-CoA hydratase
G6N27_RS11290	COG0606	chelatase, subunit chli
G6N27_RS11300	COG0138	bifunctional purine biosynthesis protein purh
G6N27_RS11340	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N27_RS11365	COG0166	Belongs to the GPI family
G6N27_RS11385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N27_RS11390	COG1950	PFAM Membrane protein of
G6N27_RS11405	COG2201	protein-glutamate methylesterase activity
G6N27_RS11450	COG0328	RNA-DNA hybrid ribonuclease activity
G6N27_RS11460	COG0300	oxidoreductase activity
G6N27_RS11475	COG1414	Transcriptional regulator
G6N27_RS11505	COG0246	Mannitol dehydrogenase
G6N27_RS11560	COG1403	HNH endonuclease
G6N27_RS11610	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS11640	COG1733	regulation of RNA biosynthetic process
G6N27_RS11680	COG1309	transcriptional regulator
G6N27_RS11685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS11700	COG0745	RESPONSE REGULATOR receiver
G6N27_RS11710	COG0545	Peptidyl-prolyl cis-trans isomerase
G6N27_RS11730	COG0259	pyridoxamine-phosphate oxidase activity
G6N27_RS11800	COG2814	Major facilitator Superfamily
G6N27_RS11815	COG0435	Glutathione S-transferase
G6N27_RS11825	COG1278	Cold shock
G6N27_RS11855	COG0183	Belongs to the thiolase family
G6N27_RS11875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS11895	COG2813	Specifically methylates the guanine in position
G6N27_RS11900	COG1024	Enoyl-CoA hydratase
G6N27_RS11900	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N27_RS11905	COG0183	Belongs to the thiolase family
G6N27_RS11920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS11935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS11945	COG3961	Belongs to the TPP enzyme family
G6N27_RS11960	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS11985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N27_RS12030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS12055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS12060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS12065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS12070	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS12090	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12130	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N27_RS12160	COG2124	cytochrome p450
G6N27_RS12195	COG1309	transcriptional regulator
G6N27_RS12200	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12205	COG0183	Belongs to the thiolase family
G6N27_RS12210	COG1024	Enoyl-CoA hydratase
G6N27_RS12215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS12220	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS12240	COG4638	Rieske (2fe-2S)
G6N27_RS12250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N27_RS12260	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12265	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12270	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12280	COG1946	Acyl-CoA thioesterase
G6N27_RS12290	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS12310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS12365	COG0581	inorganic phosphate transmembrane transporter activity
G6N27_RS12405	COG3384	dioxygenase
G6N27_RS12410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS12415	COG2267	carboxylic ester hydrolase activity
G6N27_RS12425	COG1053	succinate dehydrogenase
G6N27_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS12445	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12450	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS12475	COG2226	methyltransferase
G6N27_RS12495	COG2031	fatty acid transporter
G6N27_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS12550	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS12570	COG0640	Transcriptional regulator
G6N27_RS12580	COG0590	tRNA wobble adenosine to inosine editing
G6N27_RS12615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N27_RS12640	COG0745	RESPONSE REGULATOR receiver
G6N27_RS12650	COG3118	belongs to the thioredoxin family
G6N27_RS12660	COG2897	thiosulfate sulfurtransferase activity
G6N27_RS12670	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N27_RS12700	COG1233	COG1233 Phytoene dehydrogenase and related
G6N27_RS12745	COG2837	iron assimilation
G6N27_RS12770	COG4221	oxidoreductase activity
G6N27_RS12770	COG3321	synthase
G6N27_RS12770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS12770	COG0604	alcohol dehydrogenase
G6N27_RS12785	COG1595	DNA-templated transcription, initiation
G6N27_RS12790	COG2169	Transcriptional regulator
G6N27_RS12790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N27_RS12820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N27_RS12845	COG0386	Belongs to the glutathione peroxidase family
G6N27_RS12850	COG0477	Major facilitator Superfamily
G6N27_RS12860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6N27_RS12875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N27_RS12900	COG0183	Belongs to the thiolase family
G6N27_RS12920	COG0667	Aldo Keto reductase
G6N27_RS12955	COG4221	oxidoreductase activity
G6N27_RS12960	COG2124	cytochrome p450
G6N27_RS12995	COG2205	protein histidine kinase activity
G6N27_RS13000	COG0745	RESPONSE REGULATOR receiver
G6N27_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS13080	COG0714	Associated with various cellular activities
G6N27_RS13120	COG1234	tRNA 3'-trailer cleavage
G6N27_RS13125	COG1316	TRANSCRIPTIONal
G6N27_RS13145	COG2072	flavoprotein involved in K transport
G6N27_RS13155	COG0346	lactoylglutathione lyase activity
G6N27_RS13190	COG2072	flavoprotein involved in K transport
G6N27_RS13220	COG1053	succinate dehydrogenase
G6N27_RS13245	COG1024	Enoyl-CoA hydratase
G6N27_RS13255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6N27_RS13280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS13290	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G6N27_RS13305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS13310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS13325	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13330	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13335	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS13345	COG0028	Belongs to the TPP enzyme family
G6N27_RS13350	COG3001	Fructosamine kinase
G6N27_RS13360	COG1024	Enoyl-CoA hydratase
G6N27_RS13400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N27_RS13405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N27_RS13410	COG2124	cytochrome p450
G6N27_RS13420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS13435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6N27_RS13455	COG2226	methyltransferase
G6N27_RS13470	COG4591	ABC-type transport system involved in lipoprotein release permease component
G6N27_RS13475	COG1136	(ABC) transporter
G6N27_RS13475	COG0577	efflux transmembrane transporter activity
G6N27_RS13490	COG4638	Rieske (2fe-2S)
G6N27_RS13525	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N27_RS13530	COG3971	2-oxopent-4-enoate hydratase activity
G6N27_RS13540	COG2030	dehydratase
G6N27_RS13560	COG2030	dehydratase
G6N27_RS13565	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13570	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13575	COG2124	cytochrome p450
G6N27_RS13580	COG0183	Belongs to the thiolase family
G6N27_RS13595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N27_RS13600	COG0406	alpha-ribazole phosphatase activity
G6N27_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS13620	COG1024	Enoyl-CoA hydratase
G6N27_RS13670	COG0183	Belongs to the thiolase family
G6N27_RS13685	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13690	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS13695	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13700	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13705	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13710	COG0436	Aminotransferase
G6N27_RS13725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS13735	COG0069	glutamate synthase activity
G6N27_RS13790	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS13795	COG1309	transcriptional regulator
G6N27_RS13800	COG1609	Transcriptional regulator
G6N27_RS13805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6N27_RS13820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N27_RS13825	COG0215	cysteine-tRNA ligase activity
G6N27_RS13835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N27_RS13840	COG1329	Transcriptional regulator
G6N27_RS13870	COG3260	NADH ubiquinone oxidoreductase 20
G6N27_RS13880	COG0650	Formate hydrogenlyase subunit 4
G6N27_RS13890	COG0651	ATP synthesis coupled electron transport
G6N27_RS13895	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G6N27_RS13895	COG3261	NADH dehydrogenase
G6N27_RS13910	COG2267	carboxylic ester hydrolase activity
G6N27_RS13945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6N27_RS13950	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N27_RS13985	COG0302	gtp cyclohydrolase
G6N27_RS13990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N27_RS13995	COG2267	carboxylic ester hydrolase activity
G6N27_RS14005	COG1063	alcohol dehydrogenase
G6N27_RS14010	COG0531	amino acid
G6N27_RS14015	COG2968	Membrane
G6N27_RS14035	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N27_RS14040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6N27_RS14075	COG2855	membrane
G6N27_RS14100	COG0470	DNA polymerase III
G6N27_RS14115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6N27_RS14115	COG1754	DNA topoisomerase type I activity
G6N27_RS14125	COG1278	Cold shock
G6N27_RS14130	COG1111	helicase
G6N27_RS14130	COG1205	dead DEAH box helicase
G6N27_RS14185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N27_RS14190	COG0601	transmembrane transport
G6N27_RS14200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N27_RS14250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N27_RS14280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N27_RS14285	COG1408	metallophosphoesterase
G6N27_RS14325	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N27_RS14330	COG0693	protein deglycase activity
G6N27_RS14335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS14360	COG0714	Associated with various cellular activities
G6N27_RS14365	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G6N27_RS14390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N27_RS14410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N27_RS14415	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G6N27_RS14425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N27_RS14455	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS14460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N27_RS14485	COG2197	response regulator
G6N27_RS14500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6N27_RS14535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6N27_RS14545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6N27_RS14555	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N27_RS14575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N27_RS14600	COG1309	transcriptional regulator
G6N27_RS14670	COG1793	dna ligase
G6N27_RS14680	COG2124	cytochrome p450
G6N27_RS14690	COG0596	Alpha beta hydrolase
G6N27_RS14730	COG0590	tRNA wobble adenosine to inosine editing
G6N27_RS14740	COG0287	Prephenate dehydrogenase
G6N27_RS14755	COG1174	glycine betaine transport
G6N27_RS14770	COG5416	Lipopolysaccharide assembly protein A domain
G6N27_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS14810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N27_RS14820	COG2205	protein histidine kinase activity
G6N27_RS14825	COG0745	RESPONSE REGULATOR receiver
G6N27_RS14835	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS14955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6N27_RS14955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6N27_RS14975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N27_RS14975	COG2755	lipolytic protein G-D-S-L family
G6N27_RS14980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N27_RS14980	COG2755	lipolytic protein G-D-S-L family
G6N27_RS15005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS15025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N27_RS15065	COG2873	o-acetylhomoserine
G6N27_RS15075	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N27_RS15080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N27_RS15145	COG1403	HNH endonuclease
G6N27_RS15150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N27_RS15165	COG0604	alcohol dehydrogenase
G6N27_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS15270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N27_RS15280	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS15290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N27_RS15300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N27_RS15305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6N27_RS15310	COG0671	phosphoesterase, PA-phosphatase related
G6N27_RS15315	COG1216	Glycosyl transferase, family 2
G6N27_RS15335	COG0561	phosphatase activity
G6N27_RS15350	COG0204	Acyl-transferase
G6N27_RS15425	COG1316	TRANSCRIPTIONal
G6N27_RS15500	COG2072	flavoprotein involved in K transport
G6N27_RS15510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6N27_RS15520	COG1672	PFAM Archaeal ATPase
G6N27_RS15520	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6N27_RS15530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N27_RS15530	COG1796	DNA polymerase
G6N27_RS15560	COG0069	glutamate synthase activity
G6N27_RS15560	COG0070	glutamate synthase
G6N27_RS15560	COG0067	glutamate synthase
G6N27_RS15585	COG0464	growth
G6N27_RS15595	COG1404	Belongs to the peptidase S8 family
G6N27_RS15605	COG2894	cell division
G6N27_RS15690	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS15700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS15705	COG3654	unkown
G6N27_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS15750	COG1716	ATPase activity
G6N27_RS15775	COG0515	serine threonine protein kinase
G6N27_RS15840	COG0187	DNA topoisomerase II activity
G6N27_RS15845	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N27_RS15850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N27_RS15855	COG0592	DNA-directed DNA polymerase activity
G6N27_RS15860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N27_RS15870	COG0594	ribonuclease P activity
G6N27_RS15875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N27_RS15880	COG0706	membrane insertase activity
G6N27_RS15890	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N27_RS15895	COG1192	Involved in chromosome partitioning
G6N27_RS15910	COG3409	Peptidoglycan-binding domain 1 protein
G6N27_RS15910	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N27_RS15930	COG3300	MHYT domain
G6N27_RS15930	COG5001	Diguanylate cyclase
G6N27_RS15990	COG1678	Uncharacterized ACR, COG1678
G6N27_RS16010	COG0495	leucyl-tRNA aminoacylation
G6N27_RS16015	COG0300	oxidoreductase activity
G6N27_RS16030	COG0765	amino acid transport
G6N27_RS16080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS16090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N27_RS16110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N27_RS16115	COG0359	binds to the 23S rRNA
G6N27_RS16160	COG4638	Rieske (2fe-2S)
G6N27_RS16175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N27_RS16180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N27_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS16190	COG4638	Rieske (2fe-2S)
G6N27_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS16280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS16315	COG0071	Belongs to the small heat shock protein (HSP20) family
G6N27_RS16340	COG2814	Major facilitator Superfamily
G6N27_RS16370	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N27_RS16370	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N27_RS16385	COG1376	ErfK ybiS ycfS ynhG family protein
G6N27_RS16395	COG0723	plastoquinol--plastocyanin reductase activity
G6N27_RS16400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N27_RS16405	COG3757	hydrolase, family 25
G6N27_RS16465	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N27_RS16530	COG1937	Protein conserved in bacteria
G6N27_RS16535	COG2732	(Barnase) inhibitor
G6N27_RS16545	COG0596	Alpha beta hydrolase
G6N27_RS16555	COG0640	Transcriptional regulator
G6N27_RS16565	COG0523	cobalamin synthesis protein
G6N27_RS16580	COG3321	synthase
G6N27_RS16580	COG0604	alcohol dehydrogenase
G6N27_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS16640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS16645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS16660	COG1309	transcriptional regulator
G6N27_RS16690	COG1309	transcriptional regulator
G6N27_RS16695	COG0477	Major facilitator Superfamily
G6N27_RS16730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6N27_RS16765	COG0477	Major facilitator Superfamily
G6N27_RS16820	COG2226	methyltransferase
G6N27_RS16835	COG1309	transcriptional regulator
G6N27_RS16870	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS16875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS16880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS16895	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6N27_RS16915	COG1022	Amp-dependent synthetase and ligase
G6N27_RS16950	COG0778	Nitroreductase
G6N27_RS16950	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G6N27_RS16955	COG2226	methyltransferase
G6N27_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS16975	COG2217	Heavy metal translocating P-type atpase
G6N27_RS16980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N27_RS16990	COG1024	Enoyl-CoA hydratase
G6N27_RS16995	COG1024	Enoyl-CoA hydratase
G6N27_RS17005	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS17015	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS17040	COG2072	flavoprotein involved in K transport
G6N27_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS17050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS17055	COG0028	Belongs to the TPP enzyme family
G6N27_RS17070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N27_RS17070	COG2755	lipolytic protein G-D-S-L family
G6N27_RS17085	COG1376	ErfK ybiS ycfS ynhG family protein
G6N27_RS17100	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS17105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N27_RS17115	COG3281	Trehalose synthase
G6N27_RS17220	COG1309	transcriptional regulator
G6N27_RS17235	COG0596	Alpha beta hydrolase
G6N27_RS17250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS17260	COG0477	Major facilitator Superfamily
G6N27_RS17265	COG1733	regulation of RNA biosynthetic process
G6N27_RS17270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N27_RS17290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS17315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS17340	COG0783	Belongs to the Dps family
G6N27_RS17350	COG1309	transcriptional regulator
G6N27_RS17365	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS17390	COG2365	Tyrosine phosphatase family
G6N27_RS17405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G6N27_RS17425	COG1309	transcriptional regulator
G6N27_RS17430	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS17435	COG0626	cystathionine gamma-synthase activity
G6N27_RS17445	COG0277	FAD linked oxidase domain protein
G6N27_RS17450	COG1309	transcriptional regulator
G6N27_RS17485	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS17495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS17540	COG1454	alcohol dehydrogenase
G6N27_RS17555	COG1802	Transcriptional regulator
G6N27_RS17565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS17570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS17595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS17610	COG1714	RDD family
G6N27_RS17640	COG2814	Major facilitator Superfamily
G6N27_RS17650	COG2267	carboxylic ester hydrolase activity
G6N27_RS17670	COG4122	O-methyltransferase activity
G6N27_RS17675	COG0129	dihydroxy-acid dehydratase activity
G6N27_RS17680	COG1937	Protein conserved in bacteria
G6N27_RS17685	COG2814	Major facilitator Superfamily
G6N27_RS17690	COG1376	ErfK ybiS ycfS ynhG family protein
G6N27_RS17695	COG3590	peptidase
G6N27_RS17715	COG1832	CoA-binding protein
G6N27_RS17725	COG2409	Drug exporters of the RND superfamily
G6N27_RS17745	COG2409	Drug exporters of the RND superfamily
G6N27_RS17770	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G6N27_RS17785	COG1024	Enoyl-CoA hydratase
G6N27_RS17825	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS17830	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS17850	COG3604	Transcriptional regulator
G6N27_RS17855	COG0330	HflC and HflK could
G6N27_RS17875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N27_RS17895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N27_RS17895	COG0574	Belongs to the PEP-utilizing enzyme family
G6N27_RS17905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N27_RS17905	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N27_RS17905	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N27_RS17905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N27_RS17910	COG0167	dihydroorotate dehydrogenase activity
G6N27_RS17915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N27_RS17920	COG3383	formate dehydrogenase (NAD+) activity
G6N27_RS17925	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
G6N27_RS17930	COG3259	Nickel-dependent hydrogenase
G6N27_RS17965	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS17975	COG1024	Enoyl-CoA hydratase
G6N27_RS18005	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS18015	COG0500	methyltransferase
G6N27_RS18020	COG0297	glycogen (starch) synthase activity
G6N27_RS18065	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS18070	COG0028	Belongs to the TPP enzyme family
G6N27_RS18090	COG4981	capsule polysaccharide biosynthetic process
G6N27_RS18100	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N27_RS18115	COG2030	dehydratase
G6N27_RS18125	COG0183	Belongs to the thiolase family
G6N27_RS18130	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS18150	COG1053	succinate dehydrogenase
G6N27_RS18190	COG1984	allophanate hydrolase subunit 2
G6N27_RS18210	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS18230	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS18250	COG0346	lactoylglutathione lyase activity
G6N27_RS18270	COG0464	growth
G6N27_RS18290	COG5651	PPE family
G6N27_RS18315	COG1404	Belongs to the peptidase S8 family
G6N27_RS18335	COG4424	Sulfotransferase
G6N27_RS18350	COG0778	Nitroreductase
G6N27_RS18375	COG0842	Transport permease protein
G6N27_RS18375	COG1131	(ABC) transporter
G6N27_RS18375	COG1716	ATPase activity
G6N27_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS18440	COG1376	ErfK ybiS ycfS ynhG family protein
G6N27_RS18455	COG2208	phosphoserine phosphatase activity
G6N27_RS18455	COG2770	Histidine kinase
G6N27_RS18620	COG0717	Belongs to the dCTP deaminase family
G6N27_RS18640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N27_RS18665	COG2181	nitrate reductase activity
G6N27_RS18665	COG0247	lactate metabolic process
G6N27_RS18685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS18705	COG3467	pyridoxamine 5'-phosphate
G6N27_RS18730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N27_RS18735	COG0484	heat shock protein binding
G6N27_RS18740	COG0789	Transcriptional regulator
G6N27_RS18775	COG0542	response to heat
G6N27_RS18840	COG0586	Pfam SNARE associated Golgi protein
G6N27_RS18865	COG1994	Peptidase M50
G6N27_RS18900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N27_RS18925	COG4221	oxidoreductase activity
G6N27_RS18940	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS18945	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS18985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS18995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS19000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS19005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS19010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N27_RS19015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS19070	COG2226	methyltransferase
G6N27_RS19135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N27_RS19170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N27_RS19215	COG2234	aminopeptidase activity
G6N27_RS19260	COG2072	flavoprotein involved in K transport
G6N27_RS19265	COG0789	Transcriptional regulator
G6N27_RS19280	COG0351	phosphomethylpyrimidine kinase
G6N27_RS19290	COG3707	response regulator
G6N27_RS19305	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N27_RS19335	COG0242	peptide deformylase activity
G6N27_RS19395	COG1309	transcriptional regulator
G6N27_RS19400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N27_RS19410	COG0688	phosphatidylethanolamine metabolic process
G6N27_RS19445	COG4221	oxidoreductase activity
G6N27_RS19455	COG0459	protein refolding
G6N27_RS19465	COG2072	flavoprotein involved in K transport
G6N27_RS19475	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N27_RS19475	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N27_RS19490	COG2409	Drug exporters of the RND superfamily
G6N27_RS19495	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS19525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS19545	COG1024	Enoyl-CoA hydratase
G6N27_RS19555	COG1505	serine-type exopeptidase activity
G6N27_RS19580	COG0640	Transcriptional regulator
G6N27_RS19640	COG2733	membrane
G6N27_RS19775	COG0248	Ppx GppA phosphatase
G6N27_RS19820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS19825	COG2030	dehydratase
G6N27_RS19880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N27_RS19880	COG1648	precorrin-2 dehydrogenase activity
G6N27_RS19940	COG1113	amino acid transport
G6N27_RS19965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6N27_RS19970	COG0406	alpha-ribazole phosphatase activity
G6N27_RS19980	COG0785	Cytochrome C biogenesis protein
G6N27_RS19990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N27_RS20015	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N27_RS20020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N27_RS20050	COG4221	oxidoreductase activity
G6N27_RS20070	COG0667	Aldo Keto reductase
G6N27_RS20085	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS20090	COG1228	amidohydrolase
G6N27_RS20095	COG4948	Mandelate Racemase Muconate Lactonizing
G6N27_RS20100	COG4977	sequence-specific DNA binding
G6N27_RS20140	COG4221	oxidoreductase activity
G6N27_RS20160	COG0501	Belongs to the peptidase M48B family
G6N27_RS20180	COG2072	flavoprotein involved in K transport
G6N27_RS20205	COG1473	amidohydrolase
G6N27_RS20215	COG4585	Histidine kinase
G6N27_RS20225	COG2197	response regulator
G6N27_RS20255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N27_RS20290	COG2066	Belongs to the glutaminase family
G6N27_RS20295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS20355	COG3537	Alpha-1,2-mannosidase
G6N27_RS20395	COG0270	DNA (cytosine-5-)-methyltransferase activity
G6N27_RS20420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N27_RS20430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6N27_RS20440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N27_RS20450	COG1074	ATP-dependent DNA helicase activity
G6N27_RS20455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N27_RS20525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N27_RS20530	COG2226	methyltransferase
G6N27_RS20535	COG2267	carboxylic ester hydrolase activity
G6N27_RS20540	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6N27_RS20575	COG0346	lactoylglutathione lyase activity
G6N27_RS20585	COG1032	radical SAM domain protein
G6N27_RS20620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS20645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N27_RS20675	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N27_RS20690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N27_RS20710	COG2030	dehydratase
G6N27_RS20715	COG2030	dehydratase
G6N27_RS20730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N27_RS20755	COG4941	Belongs to the sigma-70 factor family
G6N27_RS20765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS20770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS20775	COG2267	carboxylic ester hydrolase activity
G6N27_RS20790	COG2318	DinB family
G6N27_RS20835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N27_RS20840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G6N27_RS20850	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS20890	COG0049	tRNA binding
G6N27_RS20900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N27_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS20915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6N27_RS20920	COG1834	amidinotransferase
G6N27_RS20925	COG1522	sequence-specific DNA binding
G6N27_RS20965	COG0535	radical SAM domain protein
G6N27_RS21005	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N27_RS21025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N27_RS21040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N27_RS21045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N27_RS21070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6N27_RS21085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N27_RS21120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N27_RS21155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS21160	COG0616	signal peptide processing
G6N27_RS21165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS21180	COG1063	alcohol dehydrogenase
G6N27_RS21195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N27_RS21200	COG1070	Carbohydrate kinase
G6N27_RS21210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS21255	COG2072	flavoprotein involved in K transport
G6N27_RS21260	COG0028	Belongs to the TPP enzyme family
G6N27_RS21270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N27_RS21275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N27_RS21295	COG2197	response regulator
G6N27_RS21310	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS21355	COG3794	PFAM blue (type 1) copper domain protein
G6N27_RS21400	COG2409	Drug exporters of the RND superfamily
G6N27_RS21415	COG0156	8-amino-7-oxononanoate synthase activity
G6N27_RS21420	COG3852	Histidine kinase
G6N27_RS21430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N27_RS21435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N27_RS21445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N27_RS21450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6N27_RS21460	COG0203	ribosomal protein L17
G6N27_RS21490	COG1404	Belongs to the peptidase S8 family
G6N27_RS21500	COG1674	ftsk spoiiie
G6N27_RS21510	COG4842	Belongs to the WXG100 family
G6N27_RS21515	COG4842	Belongs to the WXG100 family
G6N27_RS21535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N27_RS21565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS21580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N27_RS21600	COG0076	glutamate decarboxylase activity
G6N27_RS21625	COG0456	acetyltransferase
G6N27_RS21635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N27_RS21700	COG0714	Associated with various cellular activities
G6N27_RS21715	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS21720	COG2124	cytochrome p450
G6N27_RS21730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N27_RS21735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS21770	COG0516	GMP reductase activity
G6N27_RS21795	COG0519	Catalyzes the synthesis of GMP from XMP
G6N27_RS21795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N27_RS21845	COG0406	alpha-ribazole phosphatase activity
G6N27_RS21850	COG2030	dehydratase
G6N27_RS21875	COG0587	DNA-directed DNA polymerase activity
G6N27_RS21890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N27_RS21895	COG5002	protein histidine kinase activity
G6N27_RS21900	COG2018	Roadblock/LC7 domain
G6N27_RS21915	COG1357	PFAM Pentapeptide repeats (8 copies)
G6N27_RS21920	COG1716	ATPase activity
G6N27_RS21920	COG1131	(ABC) transporter
G6N27_RS21920	COG0842	Transport permease protein
G6N27_RS21945	COG0277	FAD linked oxidase domain protein
G6N27_RS21950	COG1403	HNH endonuclease
G6N27_RS21965	COG2873	o-acetylhomoserine
G6N27_RS21985	COG1295	ribonuclease BN
G6N27_RS21995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6N27_RS22000	COG2814	Major facilitator Superfamily
G6N27_RS22005	COG1686	Belongs to the peptidase S11 family
G6N27_RS22015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N27_RS22025	COG1595	DNA-templated transcription, initiation
G6N27_RS22090	COG3511	phospholipase C
G6N27_RS22105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N27_RS22115	COG1473	amidohydrolase
G6N27_RS22120	COG1473	amidohydrolase
G6N27_RS22120	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N27_RS22155	COG0564	pseudouridine synthase activity
G6N27_RS22185	COG1201	RNA secondary structure unwinding
G6N27_RS22190	COG1309	transcriptional regulator
G6N27_RS22225	COG4770	biotin carboxylase activity
G6N27_RS22250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N27_RS22255	COG3706	GGDEF domain
G6N27_RS22280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N27_RS22290	COG2197	response regulator
G6N27_RS22305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N27_RS22340	COG0393	Putative heavy-metal-binding
G6N27_RS22360	COG1316	TRANSCRIPTIONal
G6N27_RS22375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N27_RS22390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6N27_RS22410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N27_RS22420	COG1482	cell wall glycoprotein biosynthetic process
G6N27_RS22425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS22430	COG0531	amino acid
G6N27_RS22435	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N27_RS22455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N27_RS22480	COG5002	protein histidine kinase activity
G6N27_RS22480	COG5000	phosphorelay sensor kinase activity
G6N27_RS22485	COG5401	PFAM Sporulation and spore germination
G6N27_RS22495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N27_RS22500	COG0653	protein targeting
G6N27_RS22515	COG2326	polyphosphate kinase activity
G6N27_RS22540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS22550	COG1162	GTPase activity
G6N27_RS22555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N27_RS22560	COG2135	peptidase activity
G6N27_RS22565	COG2814	Major facilitator Superfamily
G6N27_RS22600	COG3835	regulator
G6N27_RS22615	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS22630	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS22640	COG1024	Enoyl-CoA hydratase
G6N27_RS22660	COG5662	AntiSigma factor
G6N27_RS22670	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N27_RS22685	COG1597	lipid kinase activity
G6N27_RS22705	COG0406	alpha-ribazole phosphatase activity
G6N27_RS22720	COG0513	Belongs to the DEAD box helicase family
G6N27_RS22760	COG3695	enzyme binding
G6N27_RS22765	COG0596	Alpha beta hydrolase
G6N27_RS22775	COG0210	DNA helicase
G6N27_RS22785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6N27_RS22815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N27_RS22845	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N27_RS22920	COG1017	nitric oxide dioxygenase activity
G6N27_RS22920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N27_RS22935	COG1278	Cold shock
G6N27_RS22950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N27_RS22975	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS23060	COG4638	Rieske (2fe-2S)
G6N27_RS23070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS23075	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS23185	COG0714	Associated with various cellular activities
G6N27_RS23205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS23210	COG1024	Enoyl-CoA hydratase
G6N27_RS23230	COG0713	ATP synthesis coupled electron transport
G6N27_RS23245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6N27_RS23250	COG1034	ATP synthesis coupled electron transport
G6N27_RS23270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N27_RS23305	COG0753	catalase activity
G6N27_RS23315	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS23325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N27_RS23330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N27_RS23365	COG0402	S-adenosylhomocysteine deaminase activity
G6N27_RS23400	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N27_RS23405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N27_RS23425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N27_RS23435	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS23445	COG0483	inositol monophosphate 1-phosphatase activity
G6N27_RS23450	COG0281	malic enzyme
G6N27_RS23465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N27_RS23470	COG0668	transmembrane transport
G6N27_RS23480	COG2884	Cell division ATP-binding protein ftsE
G6N27_RS23485	COG2177	Part of the ABC transporter FtsEX involved in
G6N27_RS23525	COG1396	sequence-specific DNA binding
G6N27_RS23540	COG2267	carboxylic ester hydrolase activity
G6N27_RS23560	COG0596	Alpha beta hydrolase
G6N27_RS23570	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS23585	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS23595	COG1024	Enoyl-CoA hydratase
G6N27_RS23595	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N27_RS23605	COG0300	oxidoreductase activity
G6N27_RS23640	COG0406	alpha-ribazole phosphatase activity
G6N27_RS23660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N27_RS23715	COG2267	carboxylic ester hydrolase activity
G6N27_RS23765	COG4251	negative regulation of phosphorylation
G6N27_RS23770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N27_RS23780	COG2197	response regulator
G6N27_RS23795	COG0577	efflux transmembrane transporter activity
G6N27_RS23795	COG1136	(ABC) transporter
G6N27_RS23830	COG0745	RESPONSE REGULATOR receiver
G6N27_RS23835	COG2205	protein histidine kinase activity
G6N27_RS23850	COG0148	phosphopyruvate hydratase activity
G6N27_RS23860	COG1024	Enoyl-CoA hydratase
G6N27_RS23925	COG0367	asparagine synthase
G6N27_RS23930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6N27_RS23930	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N27_RS23935	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS23975	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G6N27_RS23995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N27_RS24005	COG3485	protocatechuate 3,4-dioxygenase
G6N27_RS24030	COG1309	transcriptional regulator
G6N27_RS24035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N27_RS24040	COG2207	Transcriptional regulator
G6N27_RS24045	COG3588	fructose-bisphosphate aldolase
G6N27_RS24060	COG4638	Rieske (2fe-2S)
G6N27_RS24065	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N27_RS24075	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS24090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6N27_RS24095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N27_RS24110	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS24135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G6N27_RS24150	COG2814	Major facilitator Superfamily
G6N27_RS24155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N27_RS24190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N27_RS24195	COG3158	transport of potassium into the cell
G6N27_RS24210	COG0477	Major facilitator Superfamily
G6N27_RS24215	COG3457	Alanine racemase
G6N27_RS24225	COG1024	Enoyl-CoA hydratase
G6N27_RS24230	COG1012	belongs to the aldehyde dehydrogenase family
G6N27_RS24240	COG0058	SHG alpha-glucan phosphorylase activity
G6N27_RS24260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N27_RS24265	COG1966	Carbon starvation protein
G6N27_RS24270	COG1793	dna ligase
G6N27_RS24280	COG1960	acyl-CoA dehydrogenase activity
G6N27_RS24295	COG2186	Transcriptional regulator
G6N27_RS24315	COG1028	Short-chain dehydrogenase reductase Sdr
G6N27_RS24350	COG1309	transcriptional regulator
G6N27_RS24360	COG0300	oxidoreductase activity
G6N27_RS24375	COG2226	methyltransferase
G6N27_RS24375	COG2867	negative regulation of translational initiation
G6N27_RS24415	COG1119	ATPase activity
G6N27_RS24430	COG0406	alpha-ribazole phosphatase activity
G6N27_RS24460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N27_RS24465	COG0110	maltose O-acetyltransferase activity
G6N27_RS24470	COG0415	Belongs to the DNA photolyase family
G6N27_RS24475	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G6N27_RS24485	COG1304	FMN binding
G6N27_RS24490	COG1819	glycosyl
G6N27_RS24510	COG0702	epimerase
G6N27_RS24525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G6N27_RS24525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N27_RS24530	COG2226	methyltransferase
G6N27_RS24590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N27_RS24620	COG3046	protein related to deoxyribodipyrimidine photolyase
G6N27_RS24640	COG0318	PFAM AMP-dependent synthetase and ligase
G6N27_RS24650	COG2072	flavoprotein involved in K transport
G6N27_RS24670	COG0482	sulfurtransferase activity
G6N27_RS24685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N27_RS24710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N27_RS24730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6N27_RS24735	COG2267	carboxylic ester hydrolase activity
G6N27_RS24755	COG0028	Belongs to the TPP enzyme family
G6N27_RS24780	COG0473	3-isopropylmalate dehydrogenase activity
G6N27_RS24790	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N27_RS24835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N27_RS24840	COG1920	GTP binding
G6N27_RS24850	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N27_RS24865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N27_RS24880	COG1461	Dihydroxyacetone kinase
G6N27_RS24895	COG0656	L-ascorbic acid biosynthetic process
G6N27_RS24900	COG0656	L-ascorbic acid biosynthetic process
G6N27_RS24920	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N27_RS24925	COG0742	ribosomal rna small subunit methyltransferase
G6N27_RS24935	COG3415	Transposase
G6N27_RS24935	COG2801	Transposase and inactivated derivatives
G6N27_RS24950	COG0701	Predicted permease
G6N27_RS24955	COG3599	regulation of cell shape
G6N27_RS24980	COG1254	Belongs to the acylphosphatase family
G6N27_RS25010	COG2267	carboxylic ester hydrolase activity