locus-tag	class	description
JN183_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN183_RS00010	COG0592	DNA-directed DNA polymerase activity
JN183_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JN183_RS00025	COG0187	DNA topoisomerase II activity
JN183_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JN183_RS00030	COG1372	Participates in initiation and elongation during chromosome replication
JN183_RS00065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JN183_RS00095	COG0515	serine threonine protein kinase
JN183_RS00120	COG1716	ATPase activity
JN183_RS00150	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS00180	COG1960	acyl-CoA dehydrogenase activity
JN183_RS00260	COG0495	leucyl-tRNA aminoacylation
JN183_RS00275	COG1126	abc transporter atp-binding protein
JN183_RS00280	COG0765	amino acid transport
JN183_RS00290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS00305	COG1309	transcriptional regulator
JN183_RS00310	COG0596	Alpha beta hydrolase
JN183_RS00310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN183_RS00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN183_RS00370	COG0360	Binds together with S18 to 16S ribosomal RNA
JN183_RS00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN183_RS00450	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS00470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS00490	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JN183_RS00510	COG2124	cytochrome p450
JN183_RS00525	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN183_RS00525	COG1902	pentaerythritol trinitrate reductase activity
JN183_RS00530	COG1902	pentaerythritol trinitrate reductase activity
JN183_RS00530	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN183_RS00545	COG1960	acyl-CoA dehydrogenase activity
JN183_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS00630	COG1141	Ferredoxin
JN183_RS00645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS00675	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS00685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN183_RS00685	COG1042	CoA-binding domain protein
JN183_RS00685	COG0045	succinate-CoA ligase (ADP-forming) activity
JN183_RS00695	COG1053	succinate dehydrogenase
JN183_RS00710	COG0596	Alpha beta hydrolase
JN183_RS00725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN183_RS00730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS00740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS00745	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS00820	COG1309	transcriptional regulator
JN183_RS00825	COG1309	transcriptional regulator
JN183_RS00840	COG1278	Cold shock
JN183_RS00850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN183_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS00910	COG0277	FAD linked oxidase domain protein
JN183_RS00920	COG2267	carboxylic ester hydrolase activity
JN183_RS00925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS00935	COG1247	-acetyltransferase
JN183_RS00960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS01005	COG1309	transcriptional regulator
JN183_RS01065	COG0659	secondary active sulfate transmembrane transporter activity
JN183_RS01075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN183_RS01085	COG2124	cytochrome p450
JN183_RS01095	COG0714	Associated with various cellular activities
JN183_RS01115	COG0477	Major facilitator Superfamily
JN183_RS01135	COG0346	lactoylglutathione lyase activity
JN183_RS01175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS01195	COG4552	Acetyltransferase involved in intracellular survival and related
JN183_RS01200	COG1960	acyl-CoA dehydrogenase activity
JN183_RS01205	COG1309	transcriptional regulator
JN183_RS01220	COG5651	PPE family
JN183_RS01250	COG1404	Belongs to the peptidase S8 family
JN183_RS01270	COG0702	epimerase
JN183_RS01285	COG0067	glutamate synthase
JN183_RS01285	COG0070	glutamate synthase
JN183_RS01285	COG0069	glutamate synthase activity
JN183_RS01305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JN183_RS01305	COG1796	DNA polymerase
JN183_RS01320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN183_RS01330	COG2072	flavoprotein involved in K transport
JN183_RS01370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN183_RS01390	COG1316	TRANSCRIPTIONal
JN183_RS01480	COG0561	phosphatase activity
JN183_RS01500	COG1216	Glycosyl transferase, family 2
JN183_RS01515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JN183_RS01525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN183_RS01530	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JN183_RS01535	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS01540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN183_RS01540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN183_RS01540	COG3321	synthase
JN183_RS01545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN183_RS01560	COG1960	acyl-CoA dehydrogenase activity
JN183_RS01600	COG0640	Transcriptional regulator
JN183_RS01615	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS01620	COG0277	FAD linked oxidase domain protein
JN183_RS01635	COG1403	HNH endonuclease
JN183_RS01670	COG0604	alcohol dehydrogenase
JN183_RS01690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN183_RS01710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN183_RS01755	COG0745	RESPONSE REGULATOR receiver
JN183_RS01760	COG2205	protein histidine kinase activity
JN183_RS01770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JN183_RS01815	COG5416	Lipopolysaccharide assembly protein A domain
JN183_RS01830	COG1174	glycine betaine transport
JN183_RS01845	COG0287	Prephenate dehydrogenase
JN183_RS01855	COG0590	tRNA wobble adenosine to inosine editing
JN183_RS01880	COG1511	domain protein
JN183_RS01925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS01930	COG2301	Belongs to the HpcH HpaI aldolase family
JN183_RS01940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN183_RS01950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN183_RS01960	COG3800	Transcriptional regulator
JN183_RS01960	COG1396	sequence-specific DNA binding
JN183_RS01965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN183_RS01970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN183_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS01990	COG3804	dihydrodipicolinate reductase
JN183_RS02010	COG0596	Alpha beta hydrolase
JN183_RS02015	COG2124	cytochrome p450
JN183_RS02035	COG1793	dna ligase
JN183_RS02050	COG1335	isochorismatase
JN183_RS02090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN183_RS02115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN183_RS02125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS02140	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN183_RS02145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JN183_RS02165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JN183_RS02170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JN183_RS02215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN183_RS02220	COG0121	glutamine amidotransferase
JN183_RS02230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN183_RS02245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN183_RS02250	COG1695	Transcriptional regulator
JN183_RS02275	COG0714	Associated with various cellular activities
JN183_RS02300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS02310	COG0693	protein deglycase activity
JN183_RS02315	COG2890	protein-(glutamine-N5) methyltransferase activity
JN183_RS02340	COG2172	sigma factor antagonist activity
JN183_RS02345	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS02350	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS02365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN183_RS02405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN183_RS02410	COG1408	metallophosphoesterase
JN183_RS02445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN183_RS02460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JN183_RS02470	COG0494	nUDIX hydrolase
JN183_RS02495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN183_RS02515	COG0601	transmembrane transport
JN183_RS02520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN183_RS02550	COG0438	transferase activity, transferring glycosyl groups
JN183_RS02570	COG0789	Transcriptional regulator
JN183_RS02600	COG0582	viral genome integration into host DNA
JN183_RS02650	COG1111	helicase
JN183_RS02650	COG1205	dead DEAH box helicase
JN183_RS02675	COG0470	DNA polymerase III
JN183_RS02720	COG2027	D-alanyl-D-alanine carboxypeptidase
JN183_RS02730	COG0037	tRNA processing
JN183_RS02755	COG0657	acetylesterase activity
JN183_RS02770	COG1063	alcohol dehydrogenase
JN183_RS02780	COG2267	carboxylic ester hydrolase activity
JN183_RS02795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN183_RS02800	COG0302	gtp cyclohydrolase
JN183_RS02805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JN183_RS02810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JN183_RS02835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN183_RS02915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JN183_RS02950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JN183_RS02960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN183_RS02965	COG1121	(ABC) transporter
JN183_RS02975	COG1609	Transcriptional regulator
JN183_RS02980	COG1309	transcriptional regulator
JN183_RS02985	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03035	COG0436	Aminotransferase
JN183_RS03040	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03045	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03050	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS03060	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03075	COG0183	Belongs to the thiolase family
JN183_RS03105	COG1024	Enoyl-CoA hydratase
JN183_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS03135	COG0183	Belongs to the thiolase family
JN183_RS03140	COG2124	cytochrome p450
JN183_RS03145	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03150	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03155	COG2030	dehydratase
JN183_RS03175	COG2030	dehydratase
JN183_RS03180	COG1053	succinate dehydrogenase
JN183_RS03185	COG3971	2-oxopent-4-enoate hydratase activity
JN183_RS03190	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JN183_RS03195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN183_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS03225	COG4638	Rieske (2fe-2S)
JN183_RS03255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS03265	COG2124	cytochrome p450
JN183_RS03285	COG3001	Fructosamine kinase
JN183_RS03295	COG0028	Belongs to the TPP enzyme family
JN183_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS03315	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03320	COG1960	acyl-CoA dehydrogenase activity
JN183_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS03335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS03340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS03400	COG1024	Enoyl-CoA hydratase
JN183_RS03415	COG1316	TRANSCRIPTIONal
JN183_RS03485	COG0745	RESPONSE REGULATOR receiver
JN183_RS03490	COG2205	protein histidine kinase activity
JN183_RS03520	COG2124	cytochrome p450
JN183_RS03525	COG4221	oxidoreductase activity
JN183_RS03560	COG0667	Aldo Keto reductase
JN183_RS03595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN183_RS03615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JN183_RS03625	COG0477	Major facilitator Superfamily
JN183_RS03630	COG0477	Major facilitator Superfamily
JN183_RS03645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN183_RS03655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN183_RS03660	COG0047	phosphoribosylformylglycinamidine synthase activity
JN183_RS03670	COG0204	Acyl-transferase
JN183_RS03675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN183_RS03690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN183_RS03730	COG1017	nitric oxide dioxygenase activity
JN183_RS03730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN183_RS03740	COG2837	iron assimilation
JN183_RS03790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JN183_RS03905	COG0745	RESPONSE REGULATOR receiver
JN183_RS03930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN183_RS03970	COG0640	Transcriptional regulator
JN183_RS03975	COG0590	tRNA wobble adenosine to inosine editing
JN183_RS04005	COG4974	Belongs to the 'phage' integrase family
JN183_RS04025	COG1609	Transcriptional regulator
JN183_RS04035	COG1309	transcriptional regulator
JN183_RS04065	COG1033	growth of symbiont in host cell
JN183_RS04065	COG2409	Drug exporters of the RND superfamily
JN183_RS04100	COG1960	acyl-CoA dehydrogenase activity
JN183_RS04165	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS04170	COG1960	acyl-CoA dehydrogenase activity
JN183_RS04175	COG1309	transcriptional regulator
JN183_RS04180	COG1024	Enoyl-CoA hydratase
JN183_RS04185	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS04215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS04230	COG3344	reverse transcriptase
JN183_RS04235	COG3547	Transposase (IS116 IS110 IS902 family)
JN183_RS04250	COG2072	flavoprotein involved in K transport
JN183_RS04365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS04370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS04395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN183_RS04535	COG2272	Belongs to the type-B carboxylesterase lipase family
JN183_RS04650	COG3344	reverse transcriptase
JN183_RS04660	COG3328	transposase activity
JN183_RS04665	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN183_RS04710	COG3344	reverse transcriptase
JN183_RS04715	COG1309	transcriptional regulator
JN183_RS04730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS04760	COG2072	flavoprotein involved in K transport
JN183_RS04765	COG2072	flavoprotein involved in K transport
JN183_RS04785	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS04790	COG1960	acyl-CoA dehydrogenase activity
JN183_RS04795	COG4584	PFAM Integrase catalytic
JN183_RS04800	COG1484	DNA-dependent DNA replication
JN183_RS04830	COG1090	epimerase
JN183_RS04840	COG2030	dehydratase
JN183_RS04850	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JN183_RS04905	COG1309	transcriptional regulator
JN183_RS04920	COG0183	Belongs to the thiolase family
JN183_RS04925	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS04930	COG1024	Enoyl-CoA hydratase
JN183_RS04935	COG1960	acyl-CoA dehydrogenase activity
JN183_RS04950	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS04980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN183_RS04985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN183_RS04990	COG3328	transposase activity
JN183_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS05035	COG2124	cytochrome p450
JN183_RS05040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN183_RS05045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS05065	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN183_RS05065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN183_RS05070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN183_RS05075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS05080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS05115	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05120	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05130	COG2267	carboxylic ester hydrolase activity
JN183_RS05135	COG3479	Phenolic acid decarboxylase
JN183_RS05140	COG0183	Belongs to the thiolase family
JN183_RS05145	COG1703	isobutyryl-CoA mutase activity
JN183_RS05150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN183_RS05160	COG4585	Histidine kinase
JN183_RS05170	COG0504	CTP synthase activity
JN183_RS05175	COG1053	succinate dehydrogenase
JN183_RS05185	COG2267	carboxylic ester hydrolase activity
JN183_RS05190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS05195	COG3384	dioxygenase
JN183_RS05200	COG1053	succinate dehydrogenase
JN183_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS05225	COG2132	Multicopper oxidase
JN183_RS05240	COG2197	response regulator
JN183_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS05300	COG1024	Enoyl-CoA hydratase
JN183_RS05305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS05330	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05345	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN183_RS05365	COG4638	Rieske (2fe-2S)
JN183_RS05385	COG1024	Enoyl-CoA hydratase
JN183_RS05390	COG0183	Belongs to the thiolase family
JN183_RS05395	COG1309	transcriptional regulator
JN183_RS05425	COG2124	cytochrome p450
JN183_RS05430	COG2084	Dehydrogenase
JN183_RS05470	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JN183_RS05520	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JN183_RS05520	COG0778	Nitroreductase
JN183_RS05525	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05530	COG1960	acyl-CoA dehydrogenase activity
JN183_RS05570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS05575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS05580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS05605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN183_RS05675	COG1024	Enoyl-CoA hydratase
JN183_RS05690	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS05715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS05735	COG0183	Belongs to the thiolase family
JN183_RS05740	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN183_RS05740	COG1024	Enoyl-CoA hydratase
JN183_RS05745	COG2813	Specifically methylates the guanine in position
JN183_RS05765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS05795	COG1061	Type III restriction enzyme res subunit
JN183_RS05835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN183_RS05840	COG3304	Inner membrane component domain
JN183_RS05845	COG1278	Cold shock
JN183_RS05855	COG0435	Glutathione S-transferase
JN183_RS05870	COG2814	Major facilitator Superfamily
JN183_RS05910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JN183_RS05935	COG0259	pyridoxamine-phosphate oxidase activity
JN183_RS06065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS06105	COG0581	inorganic phosphate transmembrane transporter activity
JN183_RS06130	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS06165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN183_RS06195	COG4942	peptidase
JN183_RS06235	COG0138	bifunctional purine biosynthesis protein purh
JN183_RS06255	COG0656	L-ascorbic acid biosynthetic process
JN183_RS06265	COG1024	Enoyl-CoA hydratase
JN183_RS06280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN183_RS06285	COG1960	acyl-CoA dehydrogenase activity
JN183_RS06315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN183_RS06320	COG0315	cyclic pyranopterin monophosphate synthase activity
JN183_RS06320	COG0521	Mo-molybdopterin cofactor biosynthetic process
JN183_RS06325	COG1970	mechanosensitive ion channel activity
JN183_RS06340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN183_RS06345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JN183_RS06380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS06420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN183_RS06425	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JN183_RS06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN183_RS06430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN183_RS06475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN183_RS06485	COG1252	NADH dehydrogenase
JN183_RS06560	COG0297	glycogen (starch) synthase activity
JN183_RS06575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JN183_RS06625	COG0084	hydrolase, TatD family'
JN183_RS06640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JN183_RS06645	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS06650	COG0193	aminoacyl-tRNA hydrolase activity
JN183_RS06655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JN183_RS06700	COG1309	transcriptional regulator
JN183_RS06715	COG3956	TIGRFAM MazG family protein
JN183_RS06760	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JN183_RS06765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JN183_RS06780	COG2205	protein histidine kinase activity
JN183_RS06785	COG0745	RESPONSE REGULATOR receiver
JN183_RS06870	COG3391	amine dehydrogenase activity
JN183_RS06875	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS06885	COG0121	glutamine amidotransferase
JN183_RS06930	COG1024	Enoyl-CoA hydratase
JN183_RS06940	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS06945	COG0183	Belongs to the thiolase family
JN183_RS06950	COG2755	lipolytic protein G-D-S-L family
JN183_RS06955	COG0657	acetylesterase activity
JN183_RS06995	COG1331	Highly conserved protein containing a thioredoxin domain
JN183_RS07010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JN183_RS07020	COG0572	uridine kinase
JN183_RS07035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JN183_RS07085	COG2272	Belongs to the type-B carboxylesterase lipase family
JN183_RS07100	COG1570	exodeoxyribonuclease VII activity
JN183_RS07110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JN183_RS07120	COG0012	GTP binding
JN183_RS07190	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JN183_RS07220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN183_RS07220	COG0574	Belongs to the PEP-utilizing enzyme family
JN183_RS07255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN183_RS07260	COG0702	epimerase
JN183_RS07270	COG1309	transcriptional regulator
JN183_RS07280	COG1960	acyl-CoA dehydrogenase activity
JN183_RS07285	COG1960	acyl-CoA dehydrogenase activity
JN183_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS07300	COG0714	Associated with various cellular activities
JN183_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS07320	COG2124	cytochrome p450
JN183_RS07325	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS07430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JN183_RS07435	COG1484	DNA-dependent DNA replication
JN183_RS07445	COG0657	acetylesterase activity
JN183_RS07710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JN183_RS07790	COG0740	serine-type endopeptidase activity
JN183_RS07830	COG1024	Enoyl-CoA hydratase
JN183_RS07840	COG1755	Isoprenylcysteine carboxyl methyltransferase
JN183_RS07850	COG0702	epimerase
JN183_RS07860	COG0702	epimerase
JN183_RS07865	COG1024	Enoyl-CoA hydratase
JN183_RS07870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS07880	COG2409	Drug exporters of the RND superfamily
JN183_RS07890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JN183_RS07905	COG3467	pyridoxamine 5'-phosphate
JN183_RS07965	COG1140	nitrate reductase beta subunit
JN183_RS07980	COG1217	gtp-binding protein TYPA
JN183_RS07995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN183_RS08005	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JN183_RS08020	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN183_RS08030	COG0531	amino acid
JN183_RS08035	COG3321	synthase
JN183_RS08035	COG0604	alcohol dehydrogenase
JN183_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08050	COG0529	Catalyzes the synthesis of activated sulfate
JN183_RS08055	COG2046	Belongs to the sulfate adenylyltransferase family
JN183_RS08070	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08085	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS08095	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS08100	COG1309	transcriptional regulator
JN183_RS08125	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS08135	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08140	COG0477	Major facilitator Superfamily
JN183_RS08175	COG1611	Belongs to the LOG family
JN183_RS08180	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08190	COG0463	Glycosyl transferase, family 2
JN183_RS08200	COG0519	Catalyzes the synthesis of GMP from XMP
JN183_RS08215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JN183_RS08225	COG3559	Exporter of polyketide antibiotics
JN183_RS08230	COG1131	(ABC) transporter
JN183_RS08240	COG1309	transcriptional regulator
JN183_RS08255	COG5662	AntiSigma factor
JN183_RS08260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN183_RS08265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN183_RS08290	COG2239	Acts as a magnesium transporter
JN183_RS08330	COG0598	Magnesium transport protein CorA
JN183_RS08335	COG0039	L-malate dehydrogenase activity
JN183_RS08360	COG0567	Dehydrogenase, E1 component
JN183_RS08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN183_RS08445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN183_RS08470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN183_RS08485	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08490	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08495	COG1024	Enoyl-CoA hydratase
JN183_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08505	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08530	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08535	COG2124	cytochrome p450
JN183_RS08550	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08570	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08580	COG0657	acetylesterase activity
JN183_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08600	COG0183	Belongs to the thiolase family
JN183_RS08615	COG2124	cytochrome p450
JN183_RS08635	COG1484	DNA-dependent DNA replication
JN183_RS08640	COG4584	PFAM Integrase catalytic
JN183_RS08660	COG1309	transcriptional regulator
JN183_RS08665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS08670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS08695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN183_RS08730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS08735	COG2186	Transcriptional regulator
JN183_RS08740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08790	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08795	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08800	COG4221	oxidoreductase activity
JN183_RS08810	COG0183	Belongs to the thiolase family
JN183_RS08815	COG1024	Enoyl-CoA hydratase
JN183_RS08830	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08840	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS08870	COG0427	acetyl-CoA hydrolase
JN183_RS08875	COG1960	acyl-CoA dehydrogenase activity
JN183_RS08890	COG0183	Belongs to the thiolase family
JN183_RS08895	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS08995	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09000	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09005	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09015	COG1024	Enoyl-CoA hydratase
JN183_RS09030	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09035	COG1024	Enoyl-CoA hydratase
JN183_RS09040	COG2267	carboxylic ester hydrolase activity
JN183_RS09055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS09075	COG1024	Enoyl-CoA hydratase
JN183_RS09115	COG3971	2-oxopent-4-enoate hydratase activity
JN183_RS09125	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09130	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09135	COG0183	Belongs to the thiolase family
JN183_RS09140	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS09155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS09210	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS09230	COG1024	Enoyl-CoA hydratase
JN183_RS09240	COG0673	inositol 2-dehydrogenase activity
JN183_RS09280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS09285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS09290	COG3384	dioxygenase
JN183_RS09320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS09330	COG0778	Nitroreductase
JN183_RS09335	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09365	COG1960	acyl-CoA dehydrogenase activity
JN183_RS09375	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS09390	COG4584	PFAM Integrase catalytic
JN183_RS09395	COG1484	DNA-dependent DNA replication
JN183_RS09445	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JN183_RS09455	COG1522	sequence-specific DNA binding
JN183_RS09460	COG4638	Rieske (2fe-2S)
JN183_RS09505	COG1846	Transcriptional regulator
JN183_RS09520	COG3971	2-oxopent-4-enoate hydratase activity
JN183_RS09530	COG1942	4-Oxalocrotonate Tautomerase
JN183_RS09550	COG1309	transcriptional regulator
JN183_RS09585	COG4638	Rieske (2fe-2S)
JN183_RS09590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JN183_RS09600	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN183_RS09605	COG1309	transcriptional regulator
JN183_RS09620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS09645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN183_RS09665	COG0277	FAD linked oxidase domain protein
JN183_RS09680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS09830	COG3631	Ketosteroid isomerase-related protein
JN183_RS09835	COG0494	nUDIX hydrolase
JN183_RS09860	COG0018	arginyl-trna synthetase
JN183_RS09865	COG0019	diaminopimelate decarboxylase activity
JN183_RS09870	COG0460	homoserine dehydrogenase
JN183_RS09880	COG0083	homoserine kinase activity
JN183_RS09900	COG2890	protein-(glutamine-N5) methyltransferase activity
JN183_RS09920	COG0356	it plays a direct role in the translocation of protons across the membrane
JN183_RS09925	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN183_RS09935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN183_RS09935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JN183_RS09970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JN183_RS09990	COG5651	PPE family
JN183_RS10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JN183_RS10035	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JN183_RS10060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN183_RS10070	COG0058	SHG alpha-glucan phosphorylase activity
JN183_RS10080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JN183_RS10110	COG1234	tRNA 3'-trailer cleavage
JN183_RS10115	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JN183_RS10120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JN183_RS10145	COG3011	Protein conserved in bacteria
JN183_RS10175	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS10180	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10190	COG0183	Belongs to the thiolase family
JN183_RS10195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS10200	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10205	COG1802	Transcriptional regulator
JN183_RS10210	COG4977	sequence-specific DNA binding
JN183_RS10240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN183_RS10245	COG1024	Enoyl-CoA hydratase
JN183_RS10250	COG1024	Enoyl-CoA hydratase
JN183_RS10255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN183_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS10280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN183_RS10290	COG1024	Enoyl-CoA hydratase
JN183_RS10315	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10325	COG0183	Belongs to the thiolase family
JN183_RS10375	COG4638	Rieske (2fe-2S)
JN183_RS10385	COG2072	flavoprotein involved in K transport
JN183_RS10405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN183_RS10420	COG1309	transcriptional regulator
JN183_RS10440	COG2124	cytochrome p450
JN183_RS10445	COG0657	acetylesterase activity
JN183_RS10450	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10455	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10480	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10485	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10490	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10495	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10525	COG2124	cytochrome p450
JN183_RS10585	COG3757	hydrolase, family 25
JN183_RS10590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN183_RS10590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN183_RS10590	COG3321	synthase
JN183_RS10595	COG0736	holo-[acyl-carrier-protein] synthase activity
JN183_RS10645	COG4552	Acetyltransferase involved in intracellular survival and related
JN183_RS10650	COG2409	Drug exporters of the RND superfamily
JN183_RS10655	COG0697	spore germination
JN183_RS10660	COG1376	ErfK ybiS ycfS ynhG family protein
JN183_RS10680	COG0433	COG0433 Predicted ATPase
JN183_RS10685	COG0300	oxidoreductase activity
JN183_RS10705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN183_RS10715	COG1960	acyl-CoA dehydrogenase activity
JN183_RS10720	COG2030	dehydratase
JN183_RS10740	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN183_RS10760	COG0657	acetylesterase activity
JN183_RS10775	COG2937	Belongs to the GPAT DAPAT family
JN183_RS10790	COG0629	single-stranded DNA binding
JN183_RS10800	COG2902	Dehydrogenase
JN183_RS10820	COG0366	Alpha amylase catalytic
JN183_RS10825	COG2346	COG2346, Truncated hemoglobins
JN183_RS10850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JN183_RS10855	COG0698	ribose 5-phosphate isomerase
JN183_RS10870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN183_RS10890	COG0740	serine-type endopeptidase activity
JN183_RS10895	COG0740	serine-type endopeptidase activity
JN183_RS10900	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS10905	COG2040	homocysteine
JN183_RS10920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JN183_RS10920	COG0674	pyruvate-flavodoxin oxidoreductase activity
JN183_RS10925	COG1013	pyruvate-flavodoxin oxidoreductase activity
JN183_RS10935	COG1388	LysM domain
JN183_RS10940	COG3268	Saccharopine dehydrogenase
JN183_RS10945	COG0525	valine-tRNA ligase activity
JN183_RS10950	COG0285	dihydrofolate synthase activity
JN183_RS10960	COG0105	UTP biosynthetic process
JN183_RS10965	COG1530	ribonuclease E activity
JN183_RS10980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JN183_RS11010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN183_RS11010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JN183_RS11015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN183_RS11020	COG5002	protein histidine kinase activity
JN183_RS11025	COG0668	transmembrane transport
JN183_RS11030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN183_RS11035	COG0542	response to heat
JN183_RS11045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JN183_RS11050	COG0799	negative regulation of ribosome biogenesis
JN183_RS11060	COG2755	lipolytic protein G-D-S-L family
JN183_RS11085	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS11090	COG5651	PPE family
JN183_RS11095	COG2409	Drug exporters of the RND superfamily
JN183_RS11115	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11120	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11125	COG1555	photosystem II stabilization
JN183_RS11125	COG1596	polysaccharide export
JN183_RS11130	COG0658	competence protein
JN183_RS11130	COG2333	competence protein COMEC
JN183_RS11155	COG1305	Transglutaminase-like
JN183_RS11160	COG1733	regulation of RNA biosynthetic process
JN183_RS11175	COG1234	tRNA 3'-trailer cleavage
JN183_RS11180	COG0517	IMP dehydrogenase activity
JN183_RS11190	COG0481	GTPase activity
JN183_RS11205	COG3387	PFAM Glycoside hydrolase 15-related
JN183_RS11215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JN183_RS11220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JN183_RS11225	COG4208	sulfate ABC transporter
JN183_RS11230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN183_RS11240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN183_RS11260	COG1169	isochorismate synthase
JN183_RS11270	COG2072	flavoprotein involved in K transport
JN183_RS11290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS11295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS11315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS11325	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN183_RS11365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN183_RS11380	COG2124	cytochrome p450
JN183_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS11425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN183_RS11440	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS11475	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11490	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11500	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS11505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS11535	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11545	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11550	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11555	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN183_RS11590	COG1024	Enoyl-CoA hydratase
JN183_RS11600	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11605	COG1024	Enoyl-CoA hydratase
JN183_RS11615	COG1024	Enoyl-CoA hydratase
JN183_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS11625	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS11655	COG1024	Enoyl-CoA hydratase
JN183_RS11670	COG1960	acyl-CoA dehydrogenase activity
JN183_RS11685	COG1024	Enoyl-CoA hydratase
JN183_RS11755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN183_RS11830	COG0281	malic enzyme
JN183_RS11835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JN183_RS11850	COG1309	transcriptional regulator
JN183_RS11870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JN183_RS11875	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN183_RS11880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN183_RS11895	COG3321	synthase
JN183_RS11895	COG0604	alcohol dehydrogenase
JN183_RS11900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN183_RS11910	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JN183_RS11930	COG1595	DNA-templated transcription, initiation
JN183_RS11945	COG1420	regulation of RNA biosynthetic process
JN183_RS11950	COG0484	heat shock protein binding
JN183_RS11985	COG1982	Orn Lys Arg decarboxylase major
JN183_RS11995	COG1381	Involved in DNA repair and RecF pathway recombination
JN183_RS12020	COG0423	glycine-tRNA ligase activity
JN183_RS12065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS12080	COG1045	serine acetyltransferase
JN183_RS12095	COG2855	membrane
JN183_RS12105	COG4424	Sulfotransferase
JN183_RS12115	COG0243	molybdopterin cofactor binding
JN183_RS12130	COG1131	(ABC) transporter
JN183_RS12130	COG0842	Transport permease protein
JN183_RS12130	COG1716	ATPase activity
JN183_RS12150	COG0531	amino acid
JN183_RS12165	COG1175	transmembrane transport
JN183_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS12270	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS12290	COG0604	alcohol dehydrogenase
JN183_RS12295	COG1024	Enoyl-CoA hydratase
JN183_RS12305	COG1309	transcriptional regulator
JN183_RS12340	COG1674	ftsk spoiiie
JN183_RS12355	COG4974	Belongs to the 'phage' integrase family
JN183_RS12505	COG1484	DNA-dependent DNA replication
JN183_RS12515	COG2267	carboxylic ester hydrolase activity
JN183_RS12545	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS12570	COG2208	phosphoserine phosphatase activity
JN183_RS12570	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS12570	COG2172	sigma factor antagonist activity
JN183_RS12590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS12595	COG2226	methyltransferase
JN183_RS12675	COG2132	Multicopper oxidase
JN183_RS12700	COG0596	Alpha beta hydrolase
JN183_RS12715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN183_RS12730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS12770	COG0798	PFAM Bile acid sodium symporter
JN183_RS12795	COG2124	cytochrome p450
JN183_RS12805	COG0438	transferase activity, transferring glycosyl groups
JN183_RS12820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN183_RS12835	COG0657	acetylesterase activity
JN183_RS12840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN183_RS12855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN183_RS12875	COG1309	transcriptional regulator
JN183_RS12930	COG1487	ribonuclease activity
JN183_RS12965	COG1960	acyl-CoA dehydrogenase activity
JN183_RS12970	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN183_RS12985	COG2072	flavoprotein involved in K transport
JN183_RS13110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN183_RS13155	COG0596	Alpha beta hydrolase
JN183_RS13160	COG0346	lactoylglutathione lyase activity
JN183_RS13165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JN183_RS13325	COG0321	lipoyl(octanoyl) transferase activity
JN183_RS13360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN183_RS13370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN183_RS13375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JN183_RS13380	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN183_RS13410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN183_RS13415	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS13425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN183_RS13460	COG1845	cytochrome c oxidase, subunit III
JN183_RS13490	COG1022	Amp-dependent synthetase and ligase
JN183_RS13505	COG0003	Pfam Anion-transporting ATPase
JN183_RS13535	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JN183_RS13555	COG0142	geranyltranstransferase activity
JN183_RS13595	COG0768	penicillin binding
JN183_RS13620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JN183_RS13635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN183_RS13650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN183_RS13695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN183_RS13705	COG0167	dihydroorotate dehydrogenase activity
JN183_RS13740	COG1218	3'(2'),5'-bisphosphate nucleotidase
JN183_RS13745	COG0215	cysteine-tRNA ligase activity
JN183_RS13780	COG0604	alcohol dehydrogenase
JN183_RS13780	COG3321	synthase
JN183_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS13785	COG2124	cytochrome p450
JN183_RS13805	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS13865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS13875	COG1309	transcriptional regulator
JN183_RS13945	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JN183_RS13965	COG2378	regulation of single-species biofilm formation
JN183_RS14020	COG0300	oxidoreductase activity
JN183_RS14065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN183_RS14100	COG0412	Dienelactone hydrolase
JN183_RS14135	COG0604	alcohol dehydrogenase
JN183_RS14135	COG3321	synthase
JN183_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS14175	COG0714	Associated with various cellular activities
JN183_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS14235	COG2272	Belongs to the type-B carboxylesterase lipase family
JN183_RS14245	COG3265	gluconokinase activity
JN183_RS14255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS14280	COG1335	isochorismatase
JN183_RS14295	COG1595	DNA-templated transcription, initiation
JN183_RS14305	COG1175	transmembrane transport
JN183_RS14310	COG0395	ABC-type sugar transport system, permease component
JN183_RS14315	COG3842	ATPase activity
JN183_RS14320	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN183_RS14345	COG2837	iron assimilation
JN183_RS14355	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JN183_RS14385	COG0667	Aldo Keto reductase
JN183_RS14400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN183_RS14420	COG1960	acyl-CoA dehydrogenase activity
JN183_RS14475	COG0523	cobalamin synthesis protein
JN183_RS14480	COG1946	Acyl-CoA thioesterase
JN183_RS14490	COG2161	toxin-antitoxin pair type II binding
JN183_RS14495	COG2026	Addiction module toxin, RelE StbE family
JN183_RS14510	COG2207	Transcriptional regulator
JN183_RS14515	COG0183	Belongs to the thiolase family
JN183_RS14540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN183_RS14550	COG3118	belongs to the thioredoxin family
JN183_RS14550	COG0492	ferredoxin-NADP+ reductase activity
JN183_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS14610	COG1309	transcriptional regulator
JN183_RS14635	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS14640	COG4221	oxidoreductase activity
JN183_RS14650	COG2124	cytochrome p450
JN183_RS14655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN183_RS14675	COG0477	Major facilitator Superfamily
JN183_RS14680	COG1595	DNA-templated transcription, initiation
JN183_RS14690	COG0667	Aldo Keto reductase
JN183_RS14765	COG3971	2-oxopent-4-enoate hydratase activity
JN183_RS14800	COG0545	Peptidyl-prolyl cis-trans isomerase
JN183_RS14805	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN183_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS14840	COG2301	Belongs to the HpcH HpaI aldolase family
JN183_RS14850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN183_RS14865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS14870	COG1643	Atp-dependent helicase
JN183_RS14880	COG1024	Enoyl-CoA hydratase
JN183_RS14900	COG1063	alcohol dehydrogenase
JN183_RS14950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN183_RS14950	COG0723	plastoquinol--plastocyanin reductase activity
JN183_RS14960	COG1376	ErfK ybiS ycfS ynhG family protein
JN183_RS14975	COG3757	hydrolase, family 25
JN183_RS14980	COG0438	transferase activity, transferring glycosyl groups
JN183_RS14985	COG2226	methyltransferase
JN183_RS15015	COG3391	amine dehydrogenase activity
JN183_RS15030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS15035	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS15075	COG4977	sequence-specific DNA binding
JN183_RS15085	COG1733	regulation of RNA biosynthetic process
JN183_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS15110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN183_RS15145	COG0640	Transcriptional regulator
JN183_RS15165	COG1233	COG1233 Phytoene dehydrogenase and related
JN183_RS15175	COG1942	4-Oxalocrotonate Tautomerase
JN183_RS15205	COG1950	PFAM Membrane protein of
JN183_RS15210	COG1403	HNH endonuclease
JN183_RS15220	COG2814	Major facilitator Superfamily
JN183_RS15225	COG1546	Belongs to the CinA family
JN183_RS15225	COG1058	Belongs to the CinA family
JN183_RS15250	COG1063	alcohol dehydrogenase
JN183_RS15260	COG2070	2-Nitropropane dioxygenase
JN183_RS15300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN183_RS15345	COG0174	glutamine synthetase
JN183_RS15355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN183_RS15365	COG2193	ferroxidase activity
JN183_RS15375	COG1024	Enoyl-CoA hydratase
JN183_RS15400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN183_RS15460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS15465	COG1968	undecaprenyl-diphosphatase activity
JN183_RS15470	COG4221	oxidoreductase activity
JN183_RS15530	COG1252	NADH dehydrogenase
JN183_RS15550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JN183_RS15565	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS15570	COG1960	acyl-CoA dehydrogenase activity
JN183_RS15575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN183_RS15580	COG1253	flavin adenine dinucleotide binding
JN183_RS15585	COG1253	flavin adenine dinucleotide binding
JN183_RS15680	COG3976	FMN-binding domain protein
JN183_RS15680	COG1053	succinate dehydrogenase
JN183_RS15720	COG5651	PPE family
JN183_RS15795	COG5651	PPE family
JN183_RS15805	COG5651	PPE family
JN183_RS15815	COG5651	PPE family
JN183_RS15855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN183_RS15880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS15890	COG4584	PFAM Integrase catalytic
JN183_RS15895	COG1484	DNA-dependent DNA replication
JN183_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS15920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN183_RS15925	COG0022	dehydrogenase e1 component
JN183_RS15935	COG1024	Enoyl-CoA hydratase
JN183_RS15940	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS15945	COG4638	Rieske (2fe-2S)
JN183_RS15950	COG1053	succinate dehydrogenase
JN183_RS15985	COG2813	Specifically methylates the guanine in position
JN183_RS16050	COG4221	oxidoreductase activity
JN183_RS16080	COG4221	oxidoreductase activity
JN183_RS16085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS16090	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN183_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS16140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS16160	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS16190	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS16195	COG2072	flavoprotein involved in K transport
JN183_RS16215	COG2030	dehydratase
JN183_RS16220	COG1960	acyl-CoA dehydrogenase activity
JN183_RS16225	COG1960	acyl-CoA dehydrogenase activity
JN183_RS16235	COG0842	Transport permease protein
JN183_RS16235	COG1716	ATPase activity
JN183_RS16235	COG1131	(ABC) transporter
JN183_RS16240	COG0657	acetylesterase activity
JN183_RS16250	COG0243	molybdopterin cofactor binding
JN183_RS16270	COG2267	carboxylic ester hydrolase activity
JN183_RS16295	COG2072	flavoprotein involved in K transport
JN183_RS16310	COG0346	lactoylglutathione lyase activity
JN183_RS16325	COG0657	acetylesterase activity
JN183_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS16350	COG2072	flavoprotein involved in K transport
JN183_RS16355	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS16360	COG1960	acyl-CoA dehydrogenase activity
JN183_RS16380	COG0657	acetylesterase activity
JN183_RS16390	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS16410	COG1053	succinate dehydrogenase
JN183_RS16420	COG1403	HNH endonuclease
JN183_RS16470	COG2271	Major facilitator Superfamily
JN183_RS16475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN183_RS16475	COG0189	ligase activity
JN183_RS16505	COG1305	Transglutaminase-like
JN183_RS16515	COG1278	Cold shock
JN183_RS16580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN183_RS16590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JN183_RS16615	COG0494	nUDIX hydrolase
JN183_RS16640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JN183_RS16655	COG0647	UMP catabolic process
JN183_RS16670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JN183_RS16675	COG2094	Belongs to the DNA glycosylase MPG family
JN183_RS16685	COG1131	(ABC) transporter
JN183_RS16700	COG1309	transcriptional regulator
JN183_RS16705	COG2835	tetraacyldisaccharide 4'-kinase activity
JN183_RS16735	COG0300	oxidoreductase activity
JN183_RS16740	COG4948	Mandelate Racemase Muconate Lactonizing
JN183_RS16745	COG3707	response regulator
JN183_RS16750	COG0488	(ABC) transporter
JN183_RS16765	COG0604	alcohol dehydrogenase
JN183_RS16765	COG3321	synthase
JN183_RS16765	COG0604	alcohol dehydrogenase
JN183_RS16765	COG3321	synthase
JN183_RS16770	COG3321	synthase
JN183_RS16770	COG0604	alcohol dehydrogenase
JN183_RS16775	COG3321	synthase
JN183_RS16775	COG0604	alcohol dehydrogenase
JN183_RS16785	COG0165	Argininosuccinate lyase
JN183_RS16800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JN183_RS16815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JN183_RS16820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JN183_RS16825	COG0072	phenylalanine-tRNA ligase activity
JN183_RS16825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN183_RS16830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JN183_RS16860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JN183_RS16885	COG1309	transcriptional regulator
JN183_RS16895	COG2890	protein-(glutamine-N5) methyltransferase activity
JN183_RS16965	COG1131	(ABC) transporter
JN183_RS16965	COG1716	ATPase activity
JN183_RS16965	COG0842	Transport permease protein
JN183_RS16995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN183_RS17005	COG0237	dephospho-CoA kinase activity
JN183_RS17005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JN183_RS17015	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JN183_RS17065	COG1271	oxidase subunit
JN183_RS17070	COG1294	oxidase, subunit
JN183_RS17075	COG4988	ABC transporter
JN183_RS17080	COG1132	(ABC) transporter
JN183_RS17095	COG1946	Acyl-CoA thioesterase
JN183_RS17135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN183_RS17145	COG0387	Pfam Sodium calcium exchanger
JN183_RS17150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JN183_RS17160	COG0483	inositol monophosphate 1-phosphatase activity
JN183_RS17170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN183_RS17175	COG0131	Imidazoleglycerol-phosphate dehydratase
JN183_RS17185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN183_RS17195	COG0157	Belongs to the NadC ModD family
JN183_RS17255	COG5002	protein histidine kinase activity
JN183_RS17260	COG0668	transmembrane transport
JN183_RS17285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN183_RS17295	COG0791	NLP P60 protein
JN183_RS17295	COG3883	PFAM NLP P60 protein
JN183_RS17335	COG0671	phosphoesterase, PA-phosphatase related
JN183_RS17365	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS17390	COG0300	oxidoreductase activity
JN183_RS17400	COG2346	COG2346, Truncated hemoglobins
JN183_RS17420	COG0252	asparaginase activity
JN183_RS17430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JN183_RS17440	COG2070	2-Nitropropane dioxygenase
JN183_RS17505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN183_RS17510	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JN183_RS17535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN183_RS17550	COG3386	PFAM SMP-30 Gluconolaconase
JN183_RS17565	COG4221	oxidoreductase activity
JN183_RS17615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN183_RS17670	COG0745	RESPONSE REGULATOR receiver
JN183_RS17705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JN183_RS17710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN183_RS17725	COG2304	oxidoreductase activity
JN183_RS17735	COG0714	Associated with various cellular activities
JN183_RS17745	COG3883	PFAM NLP P60 protein
JN183_RS17745	COG0791	NLP P60 protein
JN183_RS17755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN183_RS17760	COG1309	transcriptional regulator
JN183_RS17770	COG0488	(ABC) transporter
JN183_RS17780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN183_RS17785	COG1960	acyl-CoA dehydrogenase activity
JN183_RS17815	COG2151	metal-sulfur cluster biosynthetic enzyme
JN183_RS17820	COG0822	iron-sulfur transferase activity
JN183_RS17830	COG0396	ATPase activity
JN183_RS17855	COG1131	(ABC) transporter
JN183_RS17890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JN183_RS17915	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN183_RS17920	COG0667	Aldo Keto reductase
JN183_RS17925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JN183_RS17965	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS17970	COG0657	acetylesterase activity
JN183_RS17975	COG1403	HNH endonuclease
JN183_RS17995	COG1660	Displays ATPase and GTPase activities
JN183_RS18000	COG0322	excinuclease ABC activity
JN183_RS18025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN183_RS18090	COG0657	acetylesterase activity
JN183_RS18120	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JN183_RS18145	COG0505	Belongs to the CarA family
JN183_RS18165	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JN183_RS18175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN183_RS18205	COG2188	Transcriptional regulator
JN183_RS18250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JN183_RS18275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN183_RS18280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JN183_RS18285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JN183_RS18295	COG0432	Pfam Uncharacterised protein family UPF0047
JN183_RS18360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JN183_RS18380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN183_RS18385	COG0235	Class ii aldolase
JN183_RS18390	COG1396	sequence-specific DNA binding
JN183_RS18425	COG1403	HNH endonuclease
JN183_RS18430	COG0124	histidyl-tRNA synthetase
JN183_RS18435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN183_RS18450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN183_RS18455	COG0747	negative chemotaxis
JN183_RS18460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JN183_RS18480	COG1022	Amp-dependent synthetase and ligase
JN183_RS18480	COG3320	Male sterility
JN183_RS18530	COG3766	membrane
JN183_RS18550	COG1946	Acyl-CoA thioesterase
JN183_RS18575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN183_RS18600	COG0667	Aldo Keto reductase
JN183_RS18605	COG4762	Protein conserved in bacteria
JN183_RS18620	COG2070	2-Nitropropane dioxygenase
JN183_RS18660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN183_RS18670	COG3485	protocatechuate 3,4-dioxygenase
JN183_RS18710	COG1414	Transcriptional regulator
JN183_RS18720	COG1309	transcriptional regulator
JN183_RS18725	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS18730	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN183_RS18740	COG0753	catalase activity
JN183_RS18745	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS18765	COG1024	Enoyl-CoA hydratase
JN183_RS18815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN183_RS18900	COG1511	domain protein
JN183_RS18925	COG4689	acetoacetate decarboxylase
JN183_RS18960	COG1309	transcriptional regulator
JN183_RS18980	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS19040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN183_RS19050	COG3253	May function as heme-dependent peroxidase
JN183_RS19090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JN183_RS19095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN183_RS19100	COG0531	amino acid
JN183_RS19105	COG0569	domain protein
JN183_RS19155	COG0483	inositol monophosphate 1-phosphatase activity
JN183_RS19250	COG1388	LysM domain
JN183_RS19265	COG1960	acyl-CoA dehydrogenase activity
JN183_RS19270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JN183_RS19280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JN183_RS19295	COG1196	nuclear chromosome segregation
JN183_RS19305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN183_RS19345	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN183_RS19360	COG1842	Phage shock protein A
JN183_RS19375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JN183_RS19405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN183_RS19415	COG3214	Protein conserved in bacteria
JN183_RS19440	COG1960	acyl-CoA dehydrogenase activity
JN183_RS19445	COG1960	acyl-CoA dehydrogenase activity
JN183_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS19460	COG4770	biotin carboxylase activity
JN183_RS19465	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS19485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN183_RS19535	COG0686	Belongs to the AlaDH PNT family
JN183_RS19550	COG1185	polyribonucleotide nucleotidyltransferase activity
JN183_RS19580	COG1960	acyl-CoA dehydrogenase activity
JN183_RS19585	COG0183	Belongs to the thiolase family
JN183_RS19590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JN183_RS19595	COG2977	Belongs to the P-Pant transferase superfamily
JN183_RS19600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN183_RS19625	COG1024	Enoyl-CoA hydratase
JN183_RS19635	COG0534	Mate efflux family protein
JN183_RS19640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JN183_RS19690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN183_RS19690	COG1648	precorrin-2 dehydrogenase activity
JN183_RS19715	COG0579	oxidoreductase
JN183_RS19730	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JN183_RS19745	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JN183_RS19760	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS19770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN183_RS19785	COG1492	cobalamin metabolic process
JN183_RS19810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JN183_RS19815	COG0750	zinc metalloprotease
JN183_RS19820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JN183_RS19840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JN183_RS19845	COG0575	Belongs to the CDS family
JN183_RS19865	COG0745	RESPONSE REGULATOR receiver
JN183_RS19885	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS19905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN183_RS19930	COG0154	amidase activity
JN183_RS19940	COG0052	Belongs to the universal ribosomal protein uS2 family
JN183_RS19980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JN183_RS19990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN183_RS20005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JN183_RS20025	COG0336	Belongs to the RNA methyltransferase TrmD family
JN183_RS20040	COG0228	four-way junction DNA binding
JN183_RS20050	COG1686	Belongs to the peptidase S11 family
JN183_RS20100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JN183_RS20120	COG1196	nuclear chromosome segregation
JN183_RS20135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN183_RS20145	COG0571	ribonuclease III activity
JN183_RS20160	COG0701	Predicted permease
JN183_RS20165	COG0028	Belongs to the TPP enzyme family
JN183_RS20175	COG0742	ribosomal rna small subunit methyltransferase
JN183_RS20190	COG0657	acetylesterase activity
JN183_RS20210	COG1461	Dihydroxyacetone kinase
JN183_RS20255	COG0604	alcohol dehydrogenase
JN183_RS20255	COG3321	synthase
JN183_RS20275	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN183_RS20280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN183_RS20285	COG1920	GTP binding
JN183_RS20290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JN183_RS20335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN183_RS20340	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN183_RS20345	COG2271	Major facilitator Superfamily
JN183_RS20350	COG2271	Major facilitator Superfamily
JN183_RS20355	COG0473	3-isopropylmalate dehydrogenase activity
JN183_RS20370	COG0655	NAD(P)H dehydrogenase (quinone) activity
JN183_RS20385	COG0028	Belongs to the TPP enzyme family
JN183_RS20395	COG2259	Doxx family
JN183_RS20415	COG1192	Involved in chromosome partitioning
JN183_RS20420	COG0205	6-phosphofructokinase activity
JN183_RS20465	COG0626	cystathionine gamma-synthase activity
JN183_RS20515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN183_RS20565	COG0142	geranyltranstransferase activity
JN183_RS20595	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JN183_RS20635	COG1819	glycosyl
JN183_RS20640	COG1304	FMN binding
JN183_RS20645	COG2409	Drug exporters of the RND superfamily
JN183_RS20655	COG0415	Belongs to the DNA photolyase family
JN183_RS20665	COG0110	maltose O-acetyltransferase activity
JN183_RS20670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN183_RS20695	COG1024	Enoyl-CoA hydratase
JN183_RS20705	COG1119	ATPase activity
JN183_RS20715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN183_RS20750	COG1309	transcriptional regulator
JN183_RS20760	COG2072	flavoprotein involved in K transport
JN183_RS20765	COG1309	transcriptional regulator
JN183_RS20835	COG2186	Transcriptional regulator
JN183_RS20850	COG1960	acyl-CoA dehydrogenase activity
JN183_RS20860	COG1793	dna ligase
JN183_RS20865	COG0443	Heat shock 70 kDa protein
JN183_RS20875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS20880	COG0183	Belongs to the thiolase family
JN183_RS20885	COG1024	Enoyl-CoA hydratase
JN183_RS20890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS20915	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS20930	COG2076	Multidrug Resistance protein
JN183_RS20980	COG4638	Rieske (2fe-2S)
JN183_RS20985	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS21010	COG4638	Rieske (2fe-2S)
JN183_RS21025	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS21040	COG3654	unkown
JN183_RS21060	COG0477	Major facilitator Superfamily
JN183_RS21070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN183_RS21075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN183_RS21095	COG2301	Belongs to the HpcH HpaI aldolase family
JN183_RS21110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JN183_RS21145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN183_RS21205	COG4638	Rieske (2fe-2S)
JN183_RS21225	COG2755	lipolytic protein G-D-S-L family
JN183_RS21225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN183_RS21275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JN183_RS21280	COG2177	Part of the ABC transporter FtsEX involved in
JN183_RS21285	COG2884	Cell division ATP-binding protein ftsE
JN183_RS21295	COG0668	transmembrane transport
JN183_RS21305	COG0493	'glutamate synthase
JN183_RS21345	COG0483	inositol monophosphate 1-phosphatase activity
JN183_RS21355	COG1960	acyl-CoA dehydrogenase activity
JN183_RS21360	COG0667	Aldo Keto reductase
JN183_RS21365	COG0604	alcohol dehydrogenase
JN183_RS21385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS21390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN183_RS21400	COG1960	acyl-CoA dehydrogenase activity
JN183_RS21415	COG2353	YceI-like domain
JN183_RS21435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN183_RS21455	COG1034	ATP synthesis coupled electron transport
JN183_RS21460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN183_RS21475	COG0713	ATP synthesis coupled electron transport
JN183_RS21505	COG0714	Associated with various cellular activities
JN183_RS21560	COG0297	glycogen (starch) synthase activity
JN183_RS21605	COG3237	CsbD-like
JN183_RS21615	COG2111	Na H antiporter
JN183_RS21615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JN183_RS21620	COG1006	Multisubunit Na H antiporter MnhC subunit
JN183_RS21635	COG1320	monovalent cation:proton antiporter activity
JN183_RS21640	COG2212	antiporter activity
JN183_RS21660	COG0028	Belongs to the TPP enzyme family
JN183_RS21665	COG1573	uracil-dna glycosylase
JN183_RS21720	COG0789	Transcriptional regulator
JN183_RS21730	COG3707	response regulator
JN183_RS21740	COG2197	response regulator
JN183_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS21785	COG1063	alcohol dehydrogenase
JN183_RS21845	COG0386	Belongs to the glutathione peroxidase family
JN183_RS21870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JN183_RS21880	COG0783	Belongs to the Dps family
JN183_RS21890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS21940	COG3480	Lon protease (S16) C-terminal proteolytic domain
JN183_RS21955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN183_RS21980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN183_RS22000	COG0596	Alpha beta hydrolase
JN183_RS22045	COG0513	Belongs to the DEAD box helicase family
JN183_RS22060	COG0406	alpha-ribazole phosphatase activity
JN183_RS22095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN183_RS22115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JN183_RS22120	COG1063	alcohol dehydrogenase
JN183_RS22135	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS22145	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS22165	COG2135	peptidase activity
JN183_RS22170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JN183_RS22175	COG1162	GTPase activity
JN183_RS22180	COG1733	regulation of RNA biosynthetic process
JN183_RS22185	COG0183	Belongs to the thiolase family
JN183_RS22200	COG1309	transcriptional regulator
JN183_RS22235	COG2020	methyltransferase activity
JN183_RS22240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JN183_RS22250	COG0653	protein targeting
JN183_RS22255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JN183_RS22265	COG5401	PFAM Sporulation and spore germination
JN183_RS22270	COG5002	protein histidine kinase activity
JN183_RS22270	COG5000	phosphorelay sensor kinase activity
JN183_RS22285	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN183_RS22305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN183_RS22310	COG0531	amino acid
JN183_RS22315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS22320	COG1482	cell wall glycoprotein biosynthetic process
JN183_RS22330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN183_RS22370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN183_RS22385	COG1316	TRANSCRIPTIONal
JN183_RS22410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS22415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS22455	COG0784	Response regulator, receiver
JN183_RS22460	COG4251	negative regulation of phosphorylation
JN183_RS22475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JN183_RS22480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JN183_RS22500	COG1053	succinate dehydrogenase
JN183_RS22505	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS22520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN183_RS22530	COG0424	maF-like protein
JN183_RS22545	COG4770	biotin carboxylase activity
JN183_RS22550	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS22580	COG1522	sequence-specific DNA binding
JN183_RS22590	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS22595	COG1309	transcriptional regulator
JN183_RS22600	COG1201	RNA secondary structure unwinding
JN183_RS22635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN183_RS22645	COG0564	pseudouridine synthase activity
JN183_RS22650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JN183_RS22665	COG0657	acetylesterase activity
JN183_RS22670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN183_RS22670	COG1473	amidohydrolase
JN183_RS22675	COG1473	amidohydrolase
JN183_RS22690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN183_RS22695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JN183_RS22700	COG3511	phospholipase C
JN183_RS22710	COG2304	oxidoreductase activity
JN183_RS22715	COG2304	oxidoreductase activity
JN183_RS22750	COG2009	succinate dehydrogenase
JN183_RS22760	COG1053	succinate dehydrogenase
JN183_RS22765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JN183_RS22780	COG1595	DNA-templated transcription, initiation
JN183_RS22785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN183_RS22795	COG1686	Belongs to the peptidase S11 family
JN183_RS22800	COG2814	Major facilitator Superfamily
JN183_RS22815	COG1295	ribonuclease BN
JN183_RS22840	COG2873	o-acetylhomoserine
JN183_RS22860	COG1403	HNH endonuclease
JN183_RS22885	COG1131	(ABC) transporter
JN183_RS22885	COG1716	ATPase activity
JN183_RS22885	COG0842	Transport permease protein
JN183_RS22895	COG1357	PFAM Pentapeptide repeats (8 copies)
JN183_RS22910	COG2018	Roadblock/LC7 domain
JN183_RS22915	COG5002	protein histidine kinase activity
JN183_RS22925	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JN183_RS22940	COG0587	DNA-directed DNA polymerase activity
JN183_RS22945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN183_RS22945	COG1877	trehalose-phosphatase activity
JN183_RS22950	COG2030	dehydratase
JN183_RS22955	COG0406	alpha-ribazole phosphatase activity
JN183_RS22960	COG4221	oxidoreductase activity
JN183_RS22965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS23005	COG0519	Catalyzes the synthesis of GMP from XMP
JN183_RS23005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JN183_RS23095	COG2032	superoxide dismutase activity
JN183_RS23120	COG0459	protein refolding
JN183_RS23135	COG0456	acetyltransferase
JN183_RS23140	COG0456	acetyltransferase
JN183_RS23140	COG1214	PFAM Peptidase M22, glycoprotease
JN183_RS23145	COG0802	atpase or kinase
JN183_RS23160	COG0076	glutamate decarboxylase activity
JN183_RS23180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN183_RS23200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS23230	COG4842	Belongs to the WXG100 family
JN183_RS23235	COG4842	Belongs to the WXG100 family
JN183_RS23245	COG1674	ftsk spoiiie
JN183_RS23255	COG1404	Belongs to the peptidase S8 family
JN183_RS23295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JN183_RS23300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JN183_RS23305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JN183_RS23310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JN183_RS23320	COG2205	protein histidine kinase activity
JN183_RS23370	COG3794	PFAM blue (type 1) copper domain protein
JN183_RS23395	COG1960	acyl-CoA dehydrogenase activity
JN183_RS23410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN183_RS23425	COG0028	Belongs to the TPP enzyme family
JN183_RS23430	COG0577	efflux transmembrane transporter activity
JN183_RS23430	COG1136	(ABC) transporter
JN183_RS23435	COG0577	efflux transmembrane transporter activity
JN183_RS23440	COG2226	methyltransferase
JN183_RS23450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN183_RS23470	COG0563	adenylate kinase activity
JN183_RS23480	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS23510	COG1063	alcohol dehydrogenase
JN183_RS23515	COG4221	oxidoreductase activity
JN183_RS23535	COG0616	signal peptide processing
JN183_RS23540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS23555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JN183_RS23560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JN183_RS23585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JN183_RS23600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN183_RS23610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JN183_RS23700	COG0535	radical SAM domain protein
JN183_RS23725	COG0483	inositol monophosphate 1-phosphatase activity
JN183_RS23735	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS23760	COG0049	tRNA binding
JN183_RS23770	COG1309	transcriptional regulator
JN183_RS23785	COG1024	Enoyl-CoA hydratase
JN183_RS23800	COG1960	acyl-CoA dehydrogenase activity
JN183_RS23840	COG0222	ribosome binding
JN183_RS23875	COG2318	DinB family
JN183_RS23890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS23895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS23905	COG4941	Belongs to the sigma-70 factor family
JN183_RS23925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JN183_RS23935	COG2030	dehydratase
JN183_RS23940	COG2030	dehydratase
JN183_RS23945	COG2030	dehydratase
JN183_RS23970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN183_RS23985	COG0243	molybdopterin cofactor binding
JN183_RS23995	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN183_RS24005	COG2226	methyltransferase
JN183_RS24010	COG0778	Nitroreductase
JN183_RS24015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS24020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JN183_RS24025	COG1074	ATP-dependent DNA helicase activity
JN183_RS24055	COG3537	Alpha-1,2-mannosidase
JN183_RS24075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JN183_RS24110	COG2124	cytochrome p450
JN183_RS24115	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS24125	COG1914	H( )-stimulated, divalent metal cation uptake system
JN183_RS24130	COG0243	molybdopterin cofactor binding
JN183_RS24150	COG2072	flavoprotein involved in K transport
JN183_RS24160	COG0659	secondary active sulfate transmembrane transporter activity
JN183_RS24170	COG0501	Belongs to the peptidase M48B family
JN183_RS24175	COG0142	geranyltranstransferase activity
JN183_RS24190	COG2226	methyltransferase
JN183_RS24195	COG0300	oxidoreductase activity
JN183_RS24220	COG4948	Mandelate Racemase Muconate Lactonizing
JN183_RS24225	COG1228	amidohydrolase
JN183_RS24250	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS24260	COG0667	Aldo Keto reductase
JN183_RS24275	COG4221	oxidoreductase activity
JN183_RS24285	COG0306	phosphate transporter
JN183_RS24330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN183_RS24335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JN183_RS24360	COG2894	cell division
JN183_RS24365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JN183_RS24375	COG0785	Cytochrome C biogenesis protein
JN183_RS24385	COG0406	alpha-ribazole phosphatase activity
JN183_RS24405	COG4948	Mandelate Racemase Muconate Lactonizing
JN183_RS24410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JN183_RS24420	COG1113	amino acid transport
JN183_RS24430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS24440	COG2755	lipolytic protein G-D-S-L family
JN183_RS24440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN183_RS24445	COG2755	lipolytic protein G-D-S-L family
JN183_RS24455	COG1366	Belongs to the anti-sigma-factor antagonist family
JN183_RS24525	COG2030	dehydratase
JN183_RS24595	COG0588	phosphoglycerate mutase activity
JN183_RS24605	COG0438	transferase activity, transferring glycosyl groups
JN183_RS24645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JN183_RS24670	COG2733	membrane
JN183_RS24685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN183_RS24745	COG1505	serine-type exopeptidase activity
JN183_RS24755	COG1024	Enoyl-CoA hydratase
JN183_RS24765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN183_RS24810	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN183_RS24830	COG4221	oxidoreductase activity
JN183_RS24860	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS24870	COG0738	Major facilitator superfamily
JN183_RS24885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN183_RS24935	COG2032	superoxide dismutase activity
JN183_RS24950	COG0242	peptide deformylase activity
JN183_RS24980	COG3707	response regulator
JN183_RS25050	COG1088	dTDP-glucose 4,6-dehydratase activity
JN183_RS25055	COG2234	aminopeptidase activity
JN183_RS25060	COG2234	aminopeptidase activity
JN183_RS25100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JN183_RS25100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN183_RS25120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN183_RS25140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JN183_RS25155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN183_RS25175	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS25180	COG1960	acyl-CoA dehydrogenase activity
JN183_RS25200	COG1252	NADH dehydrogenase
JN183_RS25210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN183_RS25230	COG0406	alpha-ribazole phosphatase activity
JN183_RS25240	COG1994	Peptidase M50
JN183_RS25280	COG2826	transposase and inactivated derivatives, IS30 family
JN183_RS25315	COG0542	response to heat
JN183_RS25335	COG0789	Transcriptional regulator
JN183_RS25340	COG0484	heat shock protein binding
JN183_RS25345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JN183_RS25380	COG2814	Major facilitator Superfamily
JN183_RS25395	COG0247	lactate metabolic process
JN183_RS25395	COG2181	nitrate reductase activity
JN183_RS25425	COG2226	methyltransferase
JN183_RS25430	COG0477	Major facilitator Superfamily
JN183_RS25435	COG2175	clavaminate synthase activity
JN183_RS25440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JN183_RS25475	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JN183_RS25535	COG4584	PFAM Integrase catalytic
JN183_RS25540	COG1484	DNA-dependent DNA replication
JN183_RS25605	COG1376	ErfK ybiS ycfS ynhG family protein
JN183_RS25625	COG0246	Mannitol dehydrogenase
JN183_RS25630	COG1070	Carbohydrate kinase
JN183_RS25670	COG2130	NADP-dependent
JN183_RS25730	COG0778	Nitroreductase
JN183_RS25735	COG1368	sulfuric ester hydrolase activity
JN183_RS25755	COG1404	Belongs to the peptidase S8 family
JN183_RS25805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS25810	COG0254	rRNA binding
JN183_RS25825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JN183_RS25830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JN183_RS25835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JN183_RS25875	COG0346	lactoylglutathione lyase activity
JN183_RS25890	COG1960	acyl-CoA dehydrogenase activity
JN183_RS25900	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS25910	COG2223	nitrite transmembrane transporter activity
JN183_RS25925	COG1984	allophanate hydrolase subunit 2
JN183_RS25955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN183_RS25955	COG2146	nitrite reductase [NAD(P)H] activity
JN183_RS25980	COG1053	succinate dehydrogenase
JN183_RS26005	COG1960	acyl-CoA dehydrogenase activity
JN183_RS26020	COG0183	Belongs to the thiolase family
JN183_RS26025	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS26030	COG2030	dehydratase
JN183_RS26045	COG1472	Belongs to the glycosyl hydrolase 3 family
JN183_RS26060	COG4981	capsule polysaccharide biosynthetic process
JN183_RS26070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN183_RS26130	COG0028	Belongs to the TPP enzyme family
JN183_RS26135	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS26140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JN183_RS26195	COG0586	Pfam SNARE associated Golgi protein
JN183_RS26215	COG1309	transcriptional regulator
JN183_RS26225	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS26240	COG1024	Enoyl-CoA hydratase
JN183_RS26250	COG0657	acetylesterase activity
JN183_RS26260	COG2267	carboxylic ester hydrolase activity
JN183_RS26270	COG1228	amidohydrolase
JN183_RS26295	COG1024	Enoyl-CoA hydratase
JN183_RS26305	COG2199	diguanylate cyclase activity
JN183_RS26305	COG2203	Gaf domain
JN183_RS26310	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JN183_RS26325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JN183_RS26335	COG2409	Drug exporters of the RND superfamily
JN183_RS26375	COG3590	peptidase
JN183_RS26380	COG0243	molybdopterin cofactor binding
JN183_RS26390	COG1376	ErfK ybiS ycfS ynhG family protein
JN183_RS26395	COG2814	Major facilitator Superfamily
JN183_RS26400	COG1937	Protein conserved in bacteria
JN183_RS26405	COG0129	dihydroxy-acid dehydratase activity
JN183_RS26420	COG4122	O-methyltransferase activity
JN183_RS26430	COG1472	Belongs to the glycosyl hydrolase 3 family
JN183_RS26445	COG2267	carboxylic ester hydrolase activity
JN183_RS26485	COG3619	membrane
JN183_RS26500	COG1714	RDD family
JN183_RS26515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN183_RS26540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS26545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN183_RS26555	COG1802	Transcriptional regulator
JN183_RS26580	COG0657	acetylesterase activity
JN183_RS26605	COG1063	alcohol dehydrogenase
JN183_RS26610	COG2124	cytochrome p450
JN183_RS26640	COG1960	acyl-CoA dehydrogenase activity
JN183_RS26645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS26675	COG0277	FAD linked oxidase domain protein
JN183_RS26695	COG1309	transcriptional regulator
JN183_RS26725	COG1960	acyl-CoA dehydrogenase activity
JN183_RS26730	COG2365	Tyrosine phosphatase family
JN183_RS26735	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS26740	COG1012	belongs to the aldehyde dehydrogenase family
JN183_RS26765	COG1741	Belongs to the pirin family
JN183_RS26770	COG0783	Belongs to the Dps family
JN183_RS26790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN183_RS26805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN183_RS26820	COG3585	molybdate ion transport
JN183_RS26825	COG0596	Alpha beta hydrolase
JN183_RS26845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS26880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN183_RS26890	COG3546	catalase activity
JN183_RS26925	COG1129	ABC transporter
JN183_RS26925	COG0842	Transport permease protein
JN183_RS26945	COG3281	Trehalose synthase
JN183_RS26955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN183_RS26975	COG0028	Belongs to the TPP enzyme family
JN183_RS26980	COG0583	DNA-binding transcription factor activity
JN183_RS26985	COG1376	ErfK ybiS ycfS ynhG family protein
JN183_RS27020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN183_RS27020	COG2755	lipolytic protein G-D-S-L family
JN183_RS27030	COG0028	Belongs to the TPP enzyme family
JN183_RS27035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS27040	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27045	COG2072	flavoprotein involved in K transport
JN183_RS27055	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27060	COG3386	PFAM SMP-30 Gluconolaconase
JN183_RS27070	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS27080	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS27125	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS27140	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JN183_RS27160	COG2226	methyltransferase
JN183_RS27170	COG0300	oxidoreductase activity
JN183_RS27215	COG1063	alcohol dehydrogenase
JN183_RS27235	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27240	COG2072	flavoprotein involved in K transport
JN183_RS27265	COG0583	DNA-binding transcription factor activity
JN183_RS27270	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27285	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27290	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN183_RS27325	COG1309	transcriptional regulator
JN183_RS27335	COG1028	Short-chain dehydrogenase reductase Sdr
JN183_RS27340	COG0318	PFAM AMP-dependent synthetase and ligase
JN183_RS27365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN183_RS27390	COG1960	acyl-CoA dehydrogenase activity
JN183_RS27395	COG1309	transcriptional regulator
JN183_RS27415	COG0148	phosphopyruvate hydratase activity
JN183_RS27425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN183_RS27430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN183_RS27430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN183_RS27430	COG0649	NAD binding
JN183_RS27435	COG0651	ATP synthesis coupled electron transport
JN183_RS27445	COG0650	Formate hydrogenlyase subunit 4
JN183_RS27465	COG1484	DNA-dependent DNA replication
JN183_RS27470	COG4584	PFAM Integrase catalytic
JN183_RS27475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JN183_RS27480	COG1193	negative regulation of DNA recombination
JN183_RS27555	COG2046	Belongs to the sulfate adenylyltransferase family
JN183_RS27560	COG1993	acr, cog1993
JN183_RS27580	COG0529	Catalyzes the synthesis of activated sulfate
JN183_RS27610	COG0589	response to stress
JN183_RS27665	COG3588	fructose-bisphosphate aldolase
JN183_RS27700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN183_RS27705	COG4638	Rieske (2fe-2S)
JN183_RS27715	COG2197	response regulator
JN183_RS27720	COG4585	Histidine kinase
JN183_RS27735	COG1674	ftsk spoiiie
JN183_RS27780	COG0617	tRNA 3'-terminal CCA addition
JN183_RS27815	COG1595	DNA-templated transcription, initiation
JN183_RS27835	COG3409	Peptidoglycan-binding domain 1 protein
JN183_RS27835	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN183_RS27850	COG1192	Involved in chromosome partitioning
JN183_RS27855	COG0357	Ribosomal RNA small subunit methyltransferase G
JN183_RS27865	COG0706	membrane insertase activity
JN183_RS27870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JN183_RS27975	COG0477	Major facilitator Superfamily
JN183_RS27980	COG2161	toxin-antitoxin pair type II binding