locus-tag	class	description
BWK49_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BWK49_RS00010	COG0592	DNA-directed DNA polymerase activity
BWK49_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BWK49_RS00025	COG0187	DNA topoisomerase II activity
BWK49_RS00080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWK49_RS00110	COG0515	serine threonine protein kinase
BWK49_RS00135	COG1716	ATPase activity
BWK49_RS00160	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS00190	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS00265	COG0495	leucyl-tRNA aminoacylation
BWK49_RS00280	COG1126	abc transporter atp-binding protein
BWK49_RS00285	COG0765	amino acid transport
BWK49_RS00295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS00310	COG1309	transcriptional regulator
BWK49_RS00315	COG0596	Alpha beta hydrolase
BWK49_RS00315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BWK49_RS00360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWK49_RS00375	COG0360	Binds together with S18 to 16S ribosomal RNA
BWK49_RS00400	COG1309	transcriptional regulator
BWK49_RS00410	COG3328	transposase activity
BWK49_RS00425	COG1278	Cold shock
BWK49_RS00435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWK49_RS00465	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS00470	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BWK49_RS00470	COG0778	Nitroreductase
BWK49_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS00540	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS00545	COG0277	FAD linked oxidase domain protein
BWK49_RS00555	COG2267	carboxylic ester hydrolase activity
BWK49_RS00565	COG1247	-acetyltransferase
BWK49_RS00595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS00640	COG1309	transcriptional regulator
BWK49_RS00695	COG0659	secondary active sulfate transmembrane transporter activity
BWK49_RS00705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWK49_RS00715	COG2124	cytochrome p450
BWK49_RS00725	COG0714	Associated with various cellular activities
BWK49_RS00745	COG0477	Major facilitator Superfamily
BWK49_RS00765	COG0346	lactoylglutathione lyase activity
BWK49_RS00805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS00825	COG4552	Acetyltransferase involved in intracellular survival and related
BWK49_RS00830	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS00835	COG1309	transcriptional regulator
BWK49_RS00850	COG5651	PPE family
BWK49_RS00880	COG1404	Belongs to the peptidase S8 family
BWK49_RS00900	COG0702	epimerase
BWK49_RS00920	COG0070	glutamate synthase
BWK49_RS00920	COG0067	glutamate synthase
BWK49_RS00920	COG0069	glutamate synthase activity
BWK49_RS00945	COG1796	DNA polymerase
BWK49_RS00945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWK49_RS00955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWK49_RS00965	COG2072	flavoprotein involved in K transport
BWK49_RS01010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWK49_RS01025	COG1316	TRANSCRIPTIONal
BWK49_RS01115	COG0561	phosphatase activity
BWK49_RS01135	COG1216	Glycosyl transferase, family 2
BWK49_RS01150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BWK49_RS01160	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BWK49_RS01165	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BWK49_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS01175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BWK49_RS01175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWK49_RS01175	COG3321	synthase
BWK49_RS01180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWK49_RS01185	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS01225	COG0640	Transcriptional regulator
BWK49_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS01245	COG0277	FAD linked oxidase domain protein
BWK49_RS01260	COG1403	HNH endonuclease
BWK49_RS01295	COG1063	alcohol dehydrogenase
BWK49_RS01315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS01335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BWK49_RS01350	COG0582	viral genome integration into host DNA
BWK49_RS01435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWK49_RS01460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS01495	COG3485	protocatechuate 3,4-dioxygenase
BWK49_RS01505	COG1414	Transcriptional regulator
BWK49_RS01515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS01520	COG0596	Alpha beta hydrolase
BWK49_RS01540	COG1063	alcohol dehydrogenase
BWK49_RS01545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS01565	COG4638	Rieske (2fe-2S)
BWK49_RS01590	COG0235	Class ii aldolase
BWK49_RS01600	COG3415	Transposase
BWK49_RS01600	COG2801	Transposase and inactivated derivatives
BWK49_RS01605	COG3547	Transposase (IS116 IS110 IS902 family)
BWK49_RS01615	COG3971	2-oxopent-4-enoate hydratase activity
BWK49_RS01625	COG2267	carboxylic ester hydrolase activity
BWK49_RS01665	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS01670	COG2801	Transposase and inactivated derivatives
BWK49_RS01710	COG4638	Rieske (2fe-2S)
BWK49_RS01720	COG3547	Transposase (IS116 IS110 IS902 family)
BWK49_RS01740	COG4638	Rieske (2fe-2S)
BWK49_RS01780	COG3485	protocatechuate 3,4-dioxygenase
BWK49_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS01875	COG1063	alcohol dehydrogenase
BWK49_RS01915	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS01940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BWK49_RS01950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWK49_RS01980	COG4638	Rieske (2fe-2S)
BWK49_RS02030	COG2026	Addiction module toxin, RelE StbE family
BWK49_RS02100	COG0745	RESPONSE REGULATOR receiver
BWK49_RS02105	COG2205	protein histidine kinase activity
BWK49_RS02115	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BWK49_RS02160	COG5416	Lipopolysaccharide assembly protein A domain
BWK49_RS02175	COG1174	glycine betaine transport
BWK49_RS02190	COG0287	Prephenate dehydrogenase
BWK49_RS02200	COG0590	tRNA wobble adenosine to inosine editing
BWK49_RS02275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS02280	COG2301	Belongs to the HpcH HpaI aldolase family
BWK49_RS02285	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BWK49_RS02295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWK49_RS02305	COG1396	sequence-specific DNA binding
BWK49_RS02305	COG3800	Transcriptional regulator
BWK49_RS02310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWK49_RS02315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWK49_RS02335	COG3804	dihydrodipicolinate reductase
BWK49_RS02355	COG0596	Alpha beta hydrolase
BWK49_RS02360	COG2124	cytochrome p450
BWK49_RS02380	COG1793	dna ligase
BWK49_RS02395	COG3415	Transposase
BWK49_RS02395	COG2801	Transposase and inactivated derivatives
BWK49_RS02400	COG1335	isochorismatase
BWK49_RS02435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS02460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWK49_RS02470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS02485	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWK49_RS02490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BWK49_RS02510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWK49_RS02515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BWK49_RS02560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BWK49_RS02565	COG0121	glutamine amidotransferase
BWK49_RS02575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWK49_RS02590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BWK49_RS02595	COG1695	Transcriptional regulator
BWK49_RS02620	COG0714	Associated with various cellular activities
BWK49_RS02645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS02655	COG0693	protein deglycase activity
BWK49_RS02660	COG2890	protein-(glutamine-N5) methyltransferase activity
BWK49_RS02685	COG2172	sigma factor antagonist activity
BWK49_RS02690	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS02695	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS02710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWK49_RS02735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS02740	COG1408	metallophosphoesterase
BWK49_RS02775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWK49_RS02790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWK49_RS02825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWK49_RS02845	COG0601	transmembrane transport
BWK49_RS02850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWK49_RS02920	COG1111	helicase
BWK49_RS02920	COG1205	dead DEAH box helicase
BWK49_RS02945	COG0470	DNA polymerase III
BWK49_RS02990	COG2027	D-alanyl-D-alanine carboxypeptidase
BWK49_RS03000	COG0037	tRNA processing
BWK49_RS03015	COG0657	acetylesterase activity
BWK49_RS03025	COG1403	HNH endonuclease
BWK49_RS03030	COG1063	alcohol dehydrogenase
BWK49_RS03040	COG2267	carboxylic ester hydrolase activity
BWK49_RS03050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWK49_RS03055	COG0302	gtp cyclohydrolase
BWK49_RS03060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWK49_RS03065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWK49_RS03090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BWK49_RS03105	COG3415	Transposase
BWK49_RS03105	COG2801	Transposase and inactivated derivatives
BWK49_RS03175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BWK49_RS03210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWK49_RS03220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWK49_RS03225	COG1121	(ABC) transporter
BWK49_RS03235	COG1609	Transcriptional regulator
BWK49_RS03240	COG1309	transcriptional regulator
BWK49_RS03245	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03295	COG0436	Aminotransferase
BWK49_RS03300	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03305	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03310	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03315	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS03320	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03335	COG0183	Belongs to the thiolase family
BWK49_RS03370	COG1024	Enoyl-CoA hydratase
BWK49_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS03400	COG0183	Belongs to the thiolase family
BWK49_RS03405	COG2124	cytochrome p450
BWK49_RS03410	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03415	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03420	COG2030	dehydratase
BWK49_RS03440	COG2030	dehydratase
BWK49_RS03445	COG1053	succinate dehydrogenase
BWK49_RS03450	COG3971	2-oxopent-4-enoate hydratase activity
BWK49_RS03455	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BWK49_RS03460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWK49_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS03490	COG4638	Rieske (2fe-2S)
BWK49_RS03520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS03530	COG2124	cytochrome p450
BWK49_RS03545	COG3001	Fructosamine kinase
BWK49_RS03555	COG0028	Belongs to the TPP enzyme family
BWK49_RS03570	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS03575	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03580	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS03590	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS03595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS03600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS03625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWK49_RS03660	COG1024	Enoyl-CoA hydratase
BWK49_RS03675	COG1316	TRANSCRIPTIONal
BWK49_RS03755	COG0745	RESPONSE REGULATOR receiver
BWK49_RS03760	COG2205	protein histidine kinase activity
BWK49_RS03790	COG2124	cytochrome p450
BWK49_RS03795	COG4221	oxidoreductase activity
BWK49_RS03830	COG1716	ATPase activity
BWK49_RS03840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS03870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWK49_RS03890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BWK49_RS03900	COG0477	Major facilitator Superfamily
BWK49_RS03905	COG0477	Major facilitator Superfamily
BWK49_RS03920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BWK49_RS03930	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWK49_RS03935	COG0047	phosphoribosylformylglycinamidine synthase activity
BWK49_RS03945	COG0204	Acyl-transferase
BWK49_RS04005	COG1017	nitric oxide dioxygenase activity
BWK49_RS04005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWK49_RS04015	COG2837	iron assimilation
BWK49_RS04065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWK49_RS04120	COG0745	RESPONSE REGULATOR receiver
BWK49_RS04145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWK49_RS04190	COG0640	Transcriptional regulator
BWK49_RS04195	COG0590	tRNA wobble adenosine to inosine editing
BWK49_RS04230	COG3328	transposase activity
BWK49_RS04235	COG4974	Belongs to the 'phage' integrase family
BWK49_RS04250	COG1192	Involved in chromosome partitioning
BWK49_RS04265	COG0741	lytic transglycosylase activity
BWK49_RS04265	COG0791	NLP P60 protein
BWK49_RS04385	COG1674	ftsk spoiiie
BWK49_RS04430	COG1404	Belongs to the peptidase S8 family
BWK49_RS04490	COG0464	growth
BWK49_RS04505	COG0515	serine threonine protein kinase
BWK49_RS04595	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS04610	COG1309	transcriptional regulator
BWK49_RS04615	COG1309	transcriptional regulator
BWK49_RS04680	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS04740	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS04745	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS04750	COG1309	transcriptional regulator
BWK49_RS04755	COG1024	Enoyl-CoA hydratase
BWK49_RS04760	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS04775	COG1309	transcriptional regulator
BWK49_RS04790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS04805	COG3344	reverse transcriptase
BWK49_RS04810	COG3547	Transposase (IS116 IS110 IS902 family)
BWK49_RS04825	COG2072	flavoprotein involved in K transport
BWK49_RS04910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS04915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS04940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWK49_RS05035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BWK49_RS05045	COG2272	Belongs to the type-B carboxylesterase lipase family
BWK49_RS05095	COG2409	Drug exporters of the RND superfamily
BWK49_RS05095	COG1033	growth of symbiont in host cell
BWK49_RS05125	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS05135	COG3328	transposase activity
BWK49_RS05165	COG3344	reverse transcriptase
BWK49_RS05175	COG1309	transcriptional regulator
BWK49_RS05190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS05220	COG2072	flavoprotein involved in K transport
BWK49_RS05225	COG2072	flavoprotein involved in K transport
BWK49_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS05250	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05280	COG2030	dehydratase
BWK49_RS05290	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
BWK49_RS05340	COG1309	transcriptional regulator
BWK49_RS05350	COG0183	Belongs to the thiolase family
BWK49_RS05355	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS05360	COG1024	Enoyl-CoA hydratase
BWK49_RS05365	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05380	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS05405	COG3328	transposase activity
BWK49_RS05425	COG4974	Belongs to the 'phage' integrase family
BWK49_RS05465	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS05495	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05505	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWK49_RS05535	COG2963	transposase activity
BWK49_RS05540	COG2801	Transposase and inactivated derivatives
BWK49_RS05600	COG2826	transposase and inactivated derivatives, IS30 family
BWK49_RS05635	COG3328	transposase activity
BWK49_RS05680	COG3621	Patatin-like phospholipase
BWK49_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS05750	COG2124	cytochrome p450
BWK49_RS05755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWK49_RS05760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS05780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BWK49_RS05780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BWK49_RS05785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BWK49_RS05790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS05795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS05830	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05835	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS05850	COG3479	Phenolic acid decarboxylase
BWK49_RS05860	COG1703	isobutyryl-CoA mutase activity
BWK49_RS05865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BWK49_RS05875	COG4585	Histidine kinase
BWK49_RS05890	COG1053	succinate dehydrogenase
BWK49_RS05900	COG2267	carboxylic ester hydrolase activity
BWK49_RS05905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS05910	COG3384	dioxygenase
BWK49_RS05915	COG1053	succinate dehydrogenase
BWK49_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS05940	COG2132	Multicopper oxidase
BWK49_RS05955	COG2197	response regulator
BWK49_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS06015	COG1024	Enoyl-CoA hydratase
BWK49_RS06020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS06045	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS06060	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS06070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BWK49_RS06080	COG4638	Rieske (2fe-2S)
BWK49_RS06100	COG1024	Enoyl-CoA hydratase
BWK49_RS06105	COG0183	Belongs to the thiolase family
BWK49_RS06110	COG1309	transcriptional regulator
BWK49_RS06140	COG2124	cytochrome p450
BWK49_RS06185	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS06195	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BWK49_RS06225	COG2801	Transposase and inactivated derivatives
BWK49_RS06225	COG3415	Transposase
BWK49_RS06280	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BWK49_RS06280	COG0778	Nitroreductase
BWK49_RS06285	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS06290	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS06330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS06335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS06340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS06365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWK49_RS06435	COG1024	Enoyl-CoA hydratase
BWK49_RS06450	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS06475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS06495	COG0183	Belongs to the thiolase family
BWK49_RS06500	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWK49_RS06500	COG1024	Enoyl-CoA hydratase
BWK49_RS06505	COG2813	Specifically methylates the guanine in position
BWK49_RS06525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS06555	COG1061	Type III restriction enzyme res subunit
BWK49_RS06595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BWK49_RS06600	COG3304	Inner membrane component domain
BWK49_RS06605	COG1278	Cold shock
BWK49_RS06615	COG0435	Glutathione S-transferase
BWK49_RS06630	COG2814	Major facilitator Superfamily
BWK49_RS06670	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BWK49_RS06695	COG0259	pyridoxamine-phosphate oxidase activity
BWK49_RS06835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS06880	COG0581	inorganic phosphate transmembrane transporter activity
BWK49_RS06905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS06940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWK49_RS06970	COG4942	peptidase
BWK49_RS07010	COG0138	bifunctional purine biosynthesis protein purh
BWK49_RS07030	COG0656	L-ascorbic acid biosynthetic process
BWK49_RS07040	COG1024	Enoyl-CoA hydratase
BWK49_RS07055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWK49_RS07060	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS07090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWK49_RS07095	COG0521	Mo-molybdopterin cofactor biosynthetic process
BWK49_RS07095	COG0315	cyclic pyranopterin monophosphate synthase activity
BWK49_RS07100	COG1970	mechanosensitive ion channel activity
BWK49_RS07115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWK49_RS07120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWK49_RS07155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS07185	COG1024	Enoyl-CoA hydratase
BWK49_RS07210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWK49_RS07215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWK49_RS07215	COG0131	Imidazoleglycerol-phosphate dehydratase
BWK49_RS07220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWK49_RS07220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWK49_RS07255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWK49_RS07265	COG1252	NADH dehydrogenase
BWK49_RS07300	COG0438	transferase activity, transferring glycosyl groups
BWK49_RS07300	COG0297	glycogen (starch) synthase activity
BWK49_RS07340	COG0297	glycogen (starch) synthase activity
BWK49_RS07355	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BWK49_RS07405	COG0084	hydrolase, TatD family'
BWK49_RS07420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BWK49_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS07435	COG0193	aminoacyl-tRNA hydrolase activity
BWK49_RS07440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BWK49_RS07485	COG1309	transcriptional regulator
BWK49_RS07505	COG3956	TIGRFAM MazG family protein
BWK49_RS07550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BWK49_RS07555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BWK49_RS07575	COG2205	protein histidine kinase activity
BWK49_RS07580	COG0745	RESPONSE REGULATOR receiver
BWK49_RS07635	COG3391	amine dehydrogenase activity
BWK49_RS07640	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS07655	COG0121	glutamine amidotransferase
BWK49_RS07700	COG1024	Enoyl-CoA hydratase
BWK49_RS07710	COG0183	Belongs to the thiolase family
BWK49_RS07715	COG2755	lipolytic protein G-D-S-L family
BWK49_RS07720	COG0657	acetylesterase activity
BWK49_RS07760	COG1331	Highly conserved protein containing a thioredoxin domain
BWK49_RS07775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWK49_RS07785	COG0572	uridine kinase
BWK49_RS07805	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWK49_RS07855	COG2272	Belongs to the type-B carboxylesterase lipase family
BWK49_RS07870	COG1570	exodeoxyribonuclease VII activity
BWK49_RS07880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWK49_RS07890	COG0012	GTP binding
BWK49_RS07900	COG2161	toxin-antitoxin pair type II binding
BWK49_RS07905	COG2026	Addiction module toxin, RelE StbE family
BWK49_RS07950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS07975	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BWK49_RS08005	COG0574	Belongs to the PEP-utilizing enzyme family
BWK49_RS08005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWK49_RS08040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BWK49_RS08045	COG0702	epimerase
BWK49_RS08055	COG1309	transcriptional regulator
BWK49_RS08065	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS08070	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS08100	COG2124	cytochrome p450
BWK49_RS08105	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS08110	COG0183	Belongs to the thiolase family
BWK49_RS08115	COG1024	Enoyl-CoA hydratase
BWK49_RS08125	COG1755	Isoprenylcysteine carboxyl methyltransferase
BWK49_RS08135	COG0702	epimerase
BWK49_RS08145	COG0702	epimerase
BWK49_RS08150	COG1024	Enoyl-CoA hydratase
BWK49_RS08155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS08170	COG2409	Drug exporters of the RND superfamily
BWK49_RS08180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BWK49_RS08195	COG3467	pyridoxamine 5'-phosphate
BWK49_RS08255	COG1140	nitrate reductase beta subunit
BWK49_RS08270	COG1217	gtp-binding protein TYPA
BWK49_RS08285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWK49_RS08295	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BWK49_RS08310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWK49_RS08320	COG0531	amino acid
BWK49_RS08325	COG3321	synthase
BWK49_RS08325	COG0604	alcohol dehydrogenase
BWK49_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS08340	COG0529	Catalyzes the synthesis of activated sulfate
BWK49_RS08345	COG2046	Belongs to the sulfate adenylyltransferase family
BWK49_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS08385	COG1309	transcriptional regulator
BWK49_RS08420	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS08425	COG0477	Major facilitator Superfamily
BWK49_RS08455	COG1611	Belongs to the LOG family
BWK49_RS08460	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS08470	COG0463	Glycosyl transferase, family 2
BWK49_RS08480	COG0519	Catalyzes the synthesis of GMP from XMP
BWK49_RS08495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWK49_RS08505	COG3559	Exporter of polyketide antibiotics
BWK49_RS08510	COG1131	(ABC) transporter
BWK49_RS08515	COG1309	transcriptional regulator
BWK49_RS08530	COG5662	AntiSigma factor
BWK49_RS08535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWK49_RS08560	COG2239	Acts as a magnesium transporter
BWK49_RS08605	COG0598	Magnesium transport protein CorA
BWK49_RS08610	COG0039	L-malate dehydrogenase activity
BWK49_RS08635	COG0567	Dehydrogenase, E1 component
BWK49_RS08635	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWK49_RS08680	COG0277	FAD linked oxidase domain protein
BWK49_RS08695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS08845	COG3631	Ketosteroid isomerase-related protein
BWK49_RS08850	COG0494	nUDIX hydrolase
BWK49_RS08875	COG0018	arginyl-trna synthetase
BWK49_RS08880	COG0019	diaminopimelate decarboxylase activity
BWK49_RS08885	COG0460	homoserine dehydrogenase
BWK49_RS08895	COG0083	homoserine kinase activity
BWK49_RS08905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BWK49_RS08920	COG2890	protein-(glutamine-N5) methyltransferase activity
BWK49_RS08940	COG0356	it plays a direct role in the translocation of protons across the membrane
BWK49_RS08945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWK49_RS08955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWK49_RS08955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BWK49_RS08990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWK49_RS09010	COG5651	PPE family
BWK49_RS09015	COG3391	amine dehydrogenase activity
BWK49_RS09035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWK49_RS09055	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BWK49_RS09080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWK49_RS09090	COG0058	SHG alpha-glucan phosphorylase activity
BWK49_RS09100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BWK49_RS09125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BWK49_RS09130	COG1234	tRNA 3'-trailer cleavage
BWK49_RS09135	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWK49_RS09140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWK49_RS09165	COG3011	Protein conserved in bacteria
BWK49_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS09195	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09205	COG0183	Belongs to the thiolase family
BWK49_RS09210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS09220	COG1802	Transcriptional regulator
BWK49_RS09240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWK49_RS09245	COG1024	Enoyl-CoA hydratase
BWK49_RS09250	COG1024	Enoyl-CoA hydratase
BWK49_RS09255	COG1024	Enoyl-CoA hydratase
BWK49_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWK49_RS09290	COG1024	Enoyl-CoA hydratase
BWK49_RS09315	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09325	COG0183	Belongs to the thiolase family
BWK49_RS09395	COG4638	Rieske (2fe-2S)
BWK49_RS09405	COG2072	flavoprotein involved in K transport
BWK49_RS09425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWK49_RS09440	COG1309	transcriptional regulator
BWK49_RS09460	COG2124	cytochrome p450
BWK49_RS09465	COG0657	acetylesterase activity
BWK49_RS09470	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09475	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09500	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09505	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09510	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09515	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09545	COG2124	cytochrome p450
BWK49_RS09600	COG3757	hydrolase, family 25
BWK49_RS09615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWK49_RS09615	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BWK49_RS09615	COG3321	synthase
BWK49_RS09620	COG0736	holo-[acyl-carrier-protein] synthase activity
BWK49_RS09665	COG4552	Acetyltransferase involved in intracellular survival and related
BWK49_RS09670	COG2409	Drug exporters of the RND superfamily
BWK49_RS09675	COG0697	spore germination
BWK49_RS09680	COG1376	ErfK ybiS ycfS ynhG family protein
BWK49_RS09700	COG0433	COG0433 Predicted ATPase
BWK49_RS09705	COG0300	oxidoreductase activity
BWK49_RS09725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWK49_RS09735	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS09740	COG2030	dehydratase
BWK49_RS09760	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWK49_RS09780	COG0657	acetylesterase activity
BWK49_RS09795	COG2937	Belongs to the GPAT DAPAT family
BWK49_RS09805	COG4115	mRNA cleavage
BWK49_RS09815	COG0629	single-stranded DNA binding
BWK49_RS09825	COG2902	Dehydrogenase
BWK49_RS09845	COG0366	Alpha amylase catalytic
BWK49_RS09850	COG2346	COG2346, Truncated hemoglobins
BWK49_RS09875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BWK49_RS09880	COG0698	ribose 5-phosphate isomerase
BWK49_RS09895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS09915	COG0740	serine-type endopeptidase activity
BWK49_RS09920	COG0740	serine-type endopeptidase activity
BWK49_RS09925	COG2040	homocysteine
BWK49_RS09940	COG0674	pyruvate-flavodoxin oxidoreductase activity
BWK49_RS09940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BWK49_RS09945	COG1013	pyruvate-flavodoxin oxidoreductase activity
BWK49_RS09960	COG3268	Saccharopine dehydrogenase
BWK49_RS09965	COG0525	valine-tRNA ligase activity
BWK49_RS09970	COG0285	dihydrofolate synthase activity
BWK49_RS09980	COG0105	UTP biosynthetic process
BWK49_RS09985	COG1530	ribonuclease E activity
BWK49_RS10000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BWK49_RS10030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWK49_RS10030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BWK49_RS10035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWK49_RS10040	COG5002	protein histidine kinase activity
BWK49_RS10045	COG0668	transmembrane transport
BWK49_RS10050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWK49_RS10055	COG0542	response to heat
BWK49_RS10065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BWK49_RS10070	COG0799	negative regulation of ribosome biogenesis
BWK49_RS10080	COG2755	lipolytic protein G-D-S-L family
BWK49_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS10110	COG5651	PPE family
BWK49_RS10115	COG2409	Drug exporters of the RND superfamily
BWK49_RS10140	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS10145	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS10150	COG1555	photosystem II stabilization
BWK49_RS10150	COG1596	polysaccharide export
BWK49_RS10155	COG0658	competence protein
BWK49_RS10155	COG2333	competence protein COMEC
BWK49_RS10180	COG1305	Transglutaminase-like
BWK49_RS10190	COG1234	tRNA 3'-trailer cleavage
BWK49_RS10195	COG0517	IMP dehydrogenase activity
BWK49_RS10205	COG0481	GTPase activity
BWK49_RS10220	COG3387	PFAM Glycoside hydrolase 15-related
BWK49_RS10230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BWK49_RS10235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BWK49_RS10240	COG4208	sulfate ABC transporter
BWK49_RS10245	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BWK49_RS10255	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWK49_RS10280	COG1169	isochorismate synthase
BWK49_RS10290	COG2072	flavoprotein involved in K transport
BWK49_RS10385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BWK49_RS10425	COG3321	synthase
BWK49_RS10425	COG0604	alcohol dehydrogenase
BWK49_RS10440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWK49_RS10450	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BWK49_RS10450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWK49_RS10475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS10500	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BWK49_RS10550	COG3344	reverse transcriptase
BWK49_RS10565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWK49_RS10570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BWK49_RS10585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BWK49_RS10605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS10620	COG0657	acetylesterase activity
BWK49_RS10670	COG2132	Multicopper oxidase
BWK49_RS10695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS10705	COG0019	diaminopimelate decarboxylase activity
BWK49_RS10735	COG0640	Transcriptional regulator
BWK49_RS10740	COG1937	Protein conserved in bacteria
BWK49_RS10805	COG2124	cytochrome p450
BWK49_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS10855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS10865	COG1063	alcohol dehydrogenase
BWK49_RS10890	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS10905	COG1309	transcriptional regulator
BWK49_RS10920	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS10935	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS10955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS10985	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS11000	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS11005	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS11010	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWK49_RS11020	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS11045	COG1024	Enoyl-CoA hydratase
BWK49_RS11055	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS11060	COG1024	Enoyl-CoA hydratase
BWK49_RS11070	COG1024	Enoyl-CoA hydratase
BWK49_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS11080	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS11110	COG1024	Enoyl-CoA hydratase
BWK49_RS11125	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS11140	COG1024	Enoyl-CoA hydratase
BWK49_RS11195	COG4948	Mandelate Racemase Muconate Lactonizing
BWK49_RS11200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BWK49_RS11235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWK49_RS11240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWK49_RS11255	COG3328	transposase activity
BWK49_RS11260	COG3415	Transposase
BWK49_RS11260	COG2801	Transposase and inactivated derivatives
BWK49_RS11330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BWK49_RS11345	COG1309	transcriptional regulator
BWK49_RS11350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWK49_RS11355	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWK49_RS11360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWK49_RS11375	COG3321	synthase
BWK49_RS11375	COG0604	alcohol dehydrogenase
BWK49_RS11380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWK49_RS11390	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BWK49_RS11410	COG1595	DNA-templated transcription, initiation
BWK49_RS11425	COG1420	regulation of RNA biosynthetic process
BWK49_RS11430	COG0484	heat shock protein binding
BWK49_RS11465	COG1982	Orn Lys Arg decarboxylase major
BWK49_RS11475	COG1381	Involved in DNA repair and RecF pathway recombination
BWK49_RS11500	COG0423	glycine-tRNA ligase activity
BWK49_RS11545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS11550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS11560	COG1045	serine acetyltransferase
BWK49_RS11570	COG2855	membrane
BWK49_RS11575	COG4424	Sulfotransferase
BWK49_RS11585	COG0243	molybdopterin cofactor binding
BWK49_RS11600	COG0842	Transport permease protein
BWK49_RS11600	COG1131	(ABC) transporter
BWK49_RS11600	COG1716	ATPase activity
BWK49_RS11625	COG0531	amino acid
BWK49_RS11640	COG1175	transmembrane transport
BWK49_RS11735	COG1309	transcriptional regulator
BWK49_RS11740	COG2267	carboxylic ester hydrolase activity
BWK49_RS11775	COG4638	Rieske (2fe-2S)
BWK49_RS11780	COG0596	Alpha beta hydrolase
BWK49_RS11790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BWK49_RS11805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS11820	COG4638	Rieske (2fe-2S)
BWK49_RS11860	COG1141	Ferredoxin
BWK49_RS11865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS11870	COG1309	transcriptional regulator
BWK49_RS11875	COG2124	cytochrome p450
BWK49_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS11890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS11915	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS11935	COG3629	intracellular signal transduction
BWK49_RS11935	COG3903	Transcriptional regulator
BWK49_RS11940	COG2172	sigma factor antagonist activity
BWK49_RS11940	COG2208	phosphoserine phosphatase activity
BWK49_RS11940	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS11960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS11965	COG2226	methyltransferase
BWK49_RS12045	COG2132	Multicopper oxidase
BWK49_RS12065	COG0596	Alpha beta hydrolase
BWK49_RS12080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BWK49_RS12090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BWK49_RS12095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS12110	COG2124	cytochrome p450
BWK49_RS12115	COG2267	carboxylic ester hydrolase activity
BWK49_RS12130	COG0798	PFAM Bile acid sodium symporter
BWK49_RS12165	COG0438	transferase activity, transferring glycosyl groups
BWK49_RS12180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BWK49_RS12195	COG0657	acetylesterase activity
BWK49_RS12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWK49_RS12220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWK49_RS12240	COG1309	transcriptional regulator
BWK49_RS12295	COG1487	ribonuclease activity
BWK49_RS12325	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS12330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWK49_RS12345	COG2072	flavoprotein involved in K transport
BWK49_RS12440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS12460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWK49_RS12505	COG0596	Alpha beta hydrolase
BWK49_RS12510	COG0346	lactoylglutathione lyase activity
BWK49_RS12515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BWK49_RS12750	COG4974	Belongs to the 'phage' integrase family
BWK49_RS12775	COG0321	lipoyl(octanoyl) transferase activity
BWK49_RS12810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BWK49_RS12820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWK49_RS12825	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BWK49_RS12830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BWK49_RS12860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWK49_RS12870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BWK49_RS12905	COG1845	cytochrome c oxidase, subunit III
BWK49_RS12940	COG1022	Amp-dependent synthetase and ligase
BWK49_RS12955	COG0003	Pfam Anion-transporting ATPase
BWK49_RS12985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BWK49_RS13005	COG0142	geranyltranstransferase activity
BWK49_RS13050	COG0768	penicillin binding
BWK49_RS13090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BWK49_RS13105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWK49_RS13150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWK49_RS13160	COG0167	dihydroorotate dehydrogenase activity
BWK49_RS13195	COG1218	3'(2'),5'-bisphosphate nucleotidase
BWK49_RS13200	COG0215	cysteine-tRNA ligase activity
BWK49_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS13235	COG0604	alcohol dehydrogenase
BWK49_RS13235	COG3321	synthase
BWK49_RS13240	COG2124	cytochrome p450
BWK49_RS13255	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS13275	COG0646	methionine synthase
BWK49_RS13275	COG1410	methionine synthase
BWK49_RS13330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS13340	COG1309	transcriptional regulator
BWK49_RS13415	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BWK49_RS13485	COG0300	oxidoreductase activity
BWK49_RS13530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWK49_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS13575	COG0412	Dienelactone hydrolase
BWK49_RS13610	COG3321	synthase
BWK49_RS13610	COG0604	alcohol dehydrogenase
BWK49_RS13625	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS13655	COG0714	Associated with various cellular activities
BWK49_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS13715	COG2272	Belongs to the type-B carboxylesterase lipase family
BWK49_RS13725	COG3265	gluconokinase activity
BWK49_RS13745	COG1335	isochorismatase
BWK49_RS13760	COG1595	DNA-templated transcription, initiation
BWK49_RS13770	COG1175	transmembrane transport
BWK49_RS13775	COG0395	ABC-type sugar transport system, permease component
BWK49_RS13780	COG3842	ATPase activity
BWK49_RS13785	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWK49_RS13810	COG2837	iron assimilation
BWK49_RS13820	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BWK49_RS13850	COG0667	Aldo Keto reductase
BWK49_RS13860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWK49_RS13880	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS13935	COG0523	cobalamin synthesis protein
BWK49_RS13940	COG1946	Acyl-CoA thioesterase
BWK49_RS14000	COG3621	Patatin-like phospholipase
BWK49_RS14010	COG2226	methyltransferase
BWK49_RS14060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS14080	COG1595	DNA-templated transcription, initiation
BWK49_RS14115	COG2204	response regulator
BWK49_RS14145	COG1116	anion transmembrane transporter activity
BWK49_RS14160	COG0583	DNA-binding transcription factor activity
BWK49_RS14185	COG0545	Peptidyl-prolyl cis-trans isomerase
BWK49_RS14190	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
BWK49_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS14220	COG2301	Belongs to the HpcH HpaI aldolase family
BWK49_RS14230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWK49_RS14240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS14245	COG1643	Atp-dependent helicase
BWK49_RS14255	COG1024	Enoyl-CoA hydratase
BWK49_RS14275	COG1063	alcohol dehydrogenase
BWK49_RS14325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWK49_RS14325	COG0723	plastoquinol--plastocyanin reductase activity
BWK49_RS14335	COG1376	ErfK ybiS ycfS ynhG family protein
BWK49_RS14350	COG3757	hydrolase, family 25
BWK49_RS14355	COG0438	transferase activity, transferring glycosyl groups
BWK49_RS14360	COG2226	methyltransferase
BWK49_RS14385	COG1024	Enoyl-CoA hydratase
BWK49_RS14390	COG1309	transcriptional regulator
BWK49_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS14410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS14425	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS14430	COG3391	amine dehydrogenase activity
BWK49_RS14440	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS14445	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS14500	COG4977	sequence-specific DNA binding
BWK49_RS14510	COG1733	regulation of RNA biosynthetic process
BWK49_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS14535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS14570	COG0640	Transcriptional regulator
BWK49_RS14590	COG1233	COG1233 Phytoene dehydrogenase and related
BWK49_RS14600	COG1942	4-Oxalocrotonate Tautomerase
BWK49_RS14635	COG1950	PFAM Membrane protein of
BWK49_RS14640	COG1403	HNH endonuclease
BWK49_RS14650	COG2814	Major facilitator Superfamily
BWK49_RS14655	COG1058	Belongs to the CinA family
BWK49_RS14655	COG1546	Belongs to the CinA family
BWK49_RS14680	COG1063	alcohol dehydrogenase
BWK49_RS14690	COG2070	2-Nitropropane dioxygenase
BWK49_RS14735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BWK49_RS14780	COG0174	glutamine synthetase
BWK49_RS14790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWK49_RS14800	COG2193	ferroxidase activity
BWK49_RS14810	COG1024	Enoyl-CoA hydratase
BWK49_RS14835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWK49_RS14900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS14905	COG1968	undecaprenyl-diphosphatase activity
BWK49_RS14910	COG4221	oxidoreductase activity
BWK49_RS14970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS14980	COG1252	NADH dehydrogenase
BWK49_RS15005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWK49_RS15020	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS15025	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS15030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWK49_RS15035	COG1253	flavin adenine dinucleotide binding
BWK49_RS15040	COG1253	flavin adenine dinucleotide binding
BWK49_RS15135	COG3976	FMN-binding domain protein
BWK49_RS15135	COG1053	succinate dehydrogenase
BWK49_RS15165	COG1285	pathogenesis
BWK49_RS15175	COG5651	PPE family
BWK49_RS15225	COG1404	Belongs to the peptidase S8 family
BWK49_RS15255	COG5651	PPE family
BWK49_RS15275	COG5651	PPE family
BWK49_RS15280	COG0657	acetylesterase activity
BWK49_RS15285	COG5651	PPE family
BWK49_RS15325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BWK49_RS15350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS15375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BWK49_RS15380	COG0022	dehydrogenase e1 component
BWK49_RS15390	COG1024	Enoyl-CoA hydratase
BWK49_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS15400	COG4638	Rieske (2fe-2S)
BWK49_RS15405	COG1053	succinate dehydrogenase
BWK49_RS15440	COG2813	Specifically methylates the guanine in position
BWK49_RS15500	COG4221	oxidoreductase activity
BWK49_RS15540	COG4221	oxidoreductase activity
BWK49_RS15545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS15550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWK49_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS15580	COG2226	methyltransferase
BWK49_RS15595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS15650	COG2072	flavoprotein involved in K transport
BWK49_RS15670	COG2030	dehydratase
BWK49_RS15675	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS15680	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS15685	COG0842	Transport permease protein
BWK49_RS15685	COG1131	(ABC) transporter
BWK49_RS15685	COG1716	ATPase activity
BWK49_RS15690	COG0657	acetylesterase activity
BWK49_RS15700	COG0243	molybdopterin cofactor binding
BWK49_RS15720	COG2267	carboxylic ester hydrolase activity
BWK49_RS15745	COG2072	flavoprotein involved in K transport
BWK49_RS15760	COG0346	lactoylglutathione lyase activity
BWK49_RS15800	COG2072	flavoprotein involved in K transport
BWK49_RS15805	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS15810	COG1063	alcohol dehydrogenase
BWK49_RS15820	COG1024	Enoyl-CoA hydratase
BWK49_RS15825	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS15845	COG0657	acetylesterase activity
BWK49_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS15880	COG1053	succinate dehydrogenase
BWK49_RS15945	COG2271	Major facilitator Superfamily
BWK49_RS15950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWK49_RS15950	COG0189	ligase activity
BWK49_RS15980	COG1305	Transglutaminase-like
BWK49_RS15990	COG1278	Cold shock
BWK49_RS16000	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS16060	COG0789	Transcriptional regulator
BWK49_RS16135	COG2239	Acts as a magnesium transporter
BWK49_RS16155	COG2132	Multicopper oxidase
BWK49_RS16160	COG2226	methyltransferase
BWK49_RS16170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS16240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BWK49_RS16240	COG1672	PFAM Archaeal ATPase
BWK49_RS16260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BWK49_RS16270	COG0713	ATP synthesis coupled electron transport
BWK49_RS16275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BWK49_RS16290	COG4584	PFAM Integrase catalytic
BWK49_RS16305	COG5002	protein histidine kinase activity
BWK49_RS16315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS16365	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWK49_RS16365	COG0596	Alpha beta hydrolase
BWK49_RS16380	COG0745	RESPONSE REGULATOR receiver
BWK49_RS16385	COG2205	protein histidine kinase activity
BWK49_RS16395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWK49_RS16415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWK49_RS16430	COG0604	alcohol dehydrogenase
BWK49_RS16430	COG3321	synthase
BWK49_RS16460	COG1937	Protein conserved in bacteria
BWK49_RS16470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS16480	COG0019	diaminopimelate decarboxylase activity
BWK49_RS16520	COG4584	PFAM Integrase catalytic
BWK49_RS16525	COG2161	toxin-antitoxin pair type II binding
BWK49_RS16550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWK49_RS16600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BWK49_RS16610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BWK49_RS16615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BWK49_RS16635	COG0494	nUDIX hydrolase
BWK49_RS16660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BWK49_RS16675	COG0647	UMP catabolic process
BWK49_RS16690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWK49_RS16695	COG2094	Belongs to the DNA glycosylase MPG family
BWK49_RS16705	COG1131	(ABC) transporter
BWK49_RS16715	COG1309	transcriptional regulator
BWK49_RS16720	COG2835	tetraacyldisaccharide 4'-kinase activity
BWK49_RS16750	COG0300	oxidoreductase activity
BWK49_RS16755	COG4948	Mandelate Racemase Muconate Lactonizing
BWK49_RS16760	COG3707	response regulator
BWK49_RS16765	COG0488	(ABC) transporter
BWK49_RS16780	COG0604	alcohol dehydrogenase
BWK49_RS16785	COG1309	transcriptional regulator
BWK49_RS16820	COG1902	pentaerythritol trinitrate reductase activity
BWK49_RS16840	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS16900	COG1222	aaa ATPase
BWK49_RS16905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWK49_RS16920	COG3321	synthase
BWK49_RS16920	COG0604	alcohol dehydrogenase
BWK49_RS16920	COG3321	synthase
BWK49_RS16920	COG0604	alcohol dehydrogenase
BWK49_RS16925	COG3321	synthase
BWK49_RS16925	COG0604	alcohol dehydrogenase
BWK49_RS16930	COG3321	synthase
BWK49_RS16930	COG0604	alcohol dehydrogenase
BWK49_RS16940	COG0165	Argininosuccinate lyase
BWK49_RS16955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BWK49_RS16970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BWK49_RS16975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BWK49_RS16980	COG0072	phenylalanine-tRNA ligase activity
BWK49_RS16980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWK49_RS16985	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BWK49_RS17015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BWK49_RS17035	COG1309	transcriptional regulator
BWK49_RS17055	COG2124	cytochrome p450
BWK49_RS17120	COG1131	(ABC) transporter
BWK49_RS17120	COG0842	Transport permease protein
BWK49_RS17120	COG1716	ATPase activity
BWK49_RS17150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWK49_RS17160	COG0237	dephospho-CoA kinase activity
BWK49_RS17160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWK49_RS17170	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BWK49_RS17215	COG1271	oxidase subunit
BWK49_RS17220	COG1294	oxidase, subunit
BWK49_RS17225	COG4988	ABC transporter
BWK49_RS17230	COG1132	(ABC) transporter
BWK49_RS17245	COG1946	Acyl-CoA thioesterase
BWK49_RS17285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWK49_RS17295	COG0387	Pfam Sodium calcium exchanger
BWK49_RS17300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BWK49_RS17310	COG0483	inositol monophosphate 1-phosphatase activity
BWK49_RS17320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWK49_RS17325	COG0131	Imidazoleglycerol-phosphate dehydratase
BWK49_RS17335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BWK49_RS17345	COG0157	Belongs to the NadC ModD family
BWK49_RS17405	COG5002	protein histidine kinase activity
BWK49_RS17410	COG0668	transmembrane transport
BWK49_RS17430	COG0156	8-amino-7-oxononanoate synthase activity
BWK49_RS17445	COG0791	NLP P60 protein
BWK49_RS17445	COG3883	PFAM NLP P60 protein
BWK49_RS17485	COG0671	phosphoesterase, PA-phosphatase related
BWK49_RS17515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS17540	COG0300	oxidoreductase activity
BWK49_RS17550	COG2346	COG2346, Truncated hemoglobins
BWK49_RS17570	COG0252	asparaginase activity
BWK49_RS17580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BWK49_RS17590	COG2070	2-Nitropropane dioxygenase
BWK49_RS17665	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BWK49_RS17695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWK49_RS17720	COG4221	oxidoreductase activity
BWK49_RS17775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWK49_RS17820	COG2205	protein histidine kinase activity
BWK49_RS17825	COG0745	RESPONSE REGULATOR receiver
BWK49_RS17865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BWK49_RS17880	COG2304	oxidoreductase activity
BWK49_RS17890	COG0714	Associated with various cellular activities
BWK49_RS17900	COG3883	PFAM NLP P60 protein
BWK49_RS17900	COG0791	NLP P60 protein
BWK49_RS17910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BWK49_RS17915	COG1309	transcriptional regulator
BWK49_RS17925	COG0488	(ABC) transporter
BWK49_RS17935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWK49_RS17940	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS17970	COG0251	oxidation-reduction process
BWK49_RS17990	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS18085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWK49_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS18110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWK49_RS18120	COG3118	belongs to the thioredoxin family
BWK49_RS18120	COG0492	ferredoxin-NADP+ reductase activity
BWK49_RS18135	COG2151	metal-sulfur cluster biosynthetic enzyme
BWK49_RS18140	COG0822	iron-sulfur transferase activity
BWK49_RS18150	COG0396	ATPase activity
BWK49_RS18175	COG1131	(ABC) transporter
BWK49_RS18210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWK49_RS18235	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWK49_RS18240	COG0667	Aldo Keto reductase
BWK49_RS18245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWK49_RS18265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWK49_RS18285	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS18290	COG0657	acetylesterase activity
BWK49_RS18295	COG1403	HNH endonuclease
BWK49_RS18315	COG1660	Displays ATPase and GTPase activities
BWK49_RS18320	COG0322	excinuclease ABC activity
BWK49_RS18345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BWK49_RS18410	COG0657	acetylesterase activity
BWK49_RS18450	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BWK49_RS18475	COG0505	Belongs to the CarA family
BWK49_RS18495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BWK49_RS18505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWK49_RS18535	COG2188	Transcriptional regulator
BWK49_RS18575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BWK49_RS18605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWK49_RS18610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWK49_RS18615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWK49_RS18625	COG0432	Pfam Uncharacterised protein family UPF0047
BWK49_RS18690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BWK49_RS18710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWK49_RS18715	COG0235	Class ii aldolase
BWK49_RS18720	COG1396	sequence-specific DNA binding
BWK49_RS18755	COG1403	HNH endonuclease
BWK49_RS18760	COG0124	histidyl-tRNA synthetase
BWK49_RS18780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWK49_RS18785	COG0747	negative chemotaxis
BWK49_RS18790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWK49_RS18795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWK49_RS18815	COG1022	Amp-dependent synthetase and ligase
BWK49_RS18815	COG3320	Male sterility
BWK49_RS18865	COG3766	membrane
BWK49_RS18885	COG1946	Acyl-CoA thioesterase
BWK49_RS18940	COG0667	Aldo Keto reductase
BWK49_RS18945	COG4762	Protein conserved in bacteria
BWK49_RS18960	COG2070	2-Nitropropane dioxygenase
BWK49_RS19000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWK49_RS19010	COG3485	protocatechuate 3,4-dioxygenase
BWK49_RS19050	COG1414	Transcriptional regulator
BWK49_RS19060	COG1309	transcriptional regulator
BWK49_RS19065	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS19070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BWK49_RS19080	COG0753	catalase activity
BWK49_RS19085	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS19105	COG1024	Enoyl-CoA hydratase
BWK49_RS19145	COG1511	domain protein
BWK49_RS19165	COG4689	acetoacetate decarboxylase
BWK49_RS19200	COG1309	transcriptional regulator
BWK49_RS19220	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS19280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWK49_RS19290	COG3253	May function as heme-dependent peroxidase
BWK49_RS19330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BWK49_RS19355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWK49_RS19360	COG0531	amino acid
BWK49_RS19365	COG0569	domain protein
BWK49_RS19415	COG0483	inositol monophosphate 1-phosphatase activity
BWK49_RS19510	COG1388	LysM domain
BWK49_RS19525	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS19530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWK49_RS19540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BWK49_RS19555	COG1196	nuclear chromosome segregation
BWK49_RS19565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BWK49_RS19605	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
BWK49_RS19620	COG1842	Phage shock protein A
BWK49_RS19635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWK49_RS19665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWK49_RS19675	COG3214	Protein conserved in bacteria
BWK49_RS19700	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS19705	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS19745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BWK49_RS19750	COG1403	HNH endonuclease
BWK49_RS19800	COG0686	Belongs to the AlaDH PNT family
BWK49_RS19815	COG1185	polyribonucleotide nucleotidyltransferase activity
BWK49_RS19845	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS19850	COG0183	Belongs to the thiolase family
BWK49_RS19855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BWK49_RS19860	COG2977	Belongs to the P-Pant transferase superfamily
BWK49_RS19865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BWK49_RS19900	COG0534	Mate efflux family protein
BWK49_RS19905	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWK49_RS19915	COG0481	GTPase activity
BWK49_RS19955	COG1648	precorrin-2 dehydrogenase activity
BWK49_RS19955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWK49_RS19980	COG0579	oxidoreductase
BWK49_RS19995	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BWK49_RS20005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BWK49_RS20010	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
BWK49_RS20025	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS20035	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BWK49_RS20050	COG1492	cobalamin metabolic process
BWK49_RS20075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BWK49_RS20080	COG0750	zinc metalloprotease
BWK49_RS20085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BWK49_RS20105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BWK49_RS20110	COG0575	Belongs to the CDS family
BWK49_RS20130	COG0745	RESPONSE REGULATOR receiver
BWK49_RS20145	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS20165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BWK49_RS20190	COG0154	amidase activity
BWK49_RS20200	COG0052	Belongs to the universal ribosomal protein uS2 family
BWK49_RS20245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWK49_RS20270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BWK49_RS20290	COG0336	Belongs to the RNA methyltransferase TrmD family
BWK49_RS20295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BWK49_RS20305	COG0228	four-way junction DNA binding
BWK49_RS20315	COG1686	Belongs to the peptidase S11 family
BWK49_RS20360	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BWK49_RS20380	COG1196	nuclear chromosome segregation
BWK49_RS20395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWK49_RS20405	COG0571	ribonuclease III activity
BWK49_RS20420	COG0701	Predicted permease
BWK49_RS20425	COG0028	Belongs to the TPP enzyme family
BWK49_RS20440	COG3328	transposase activity
BWK49_RS20450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWK49_RS20560	COG2239	Acts as a magnesium transporter
BWK49_RS20575	COG3415	Transposase
BWK49_RS20575	COG2801	Transposase and inactivated derivatives
BWK49_RS20580	COG3344	reverse transcriptase
BWK49_RS20610	COG5651	PPE family
BWK49_RS20615	COG1914	H( )-stimulated, divalent metal cation uptake system
BWK49_RS20660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS20685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS20735	COG0742	ribosomal rna small subunit methyltransferase
BWK49_RS20750	COG0657	acetylesterase activity
BWK49_RS20770	COG1461	Dihydroxyacetone kinase
BWK49_RS20815	COG3321	synthase
BWK49_RS20815	COG0604	alcohol dehydrogenase
BWK49_RS20835	COG1181	Belongs to the D-alanine--D-alanine ligase family
BWK49_RS20840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BWK49_RS20845	COG1920	GTP binding
BWK49_RS20850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BWK49_RS20895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWK49_RS20900	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWK49_RS20905	COG2271	Major facilitator Superfamily
BWK49_RS20910	COG2271	Major facilitator Superfamily
BWK49_RS20915	COG0473	3-isopropylmalate dehydrogenase activity
BWK49_RS20930	COG0655	NAD(P)H dehydrogenase (quinone) activity
BWK49_RS20945	COG0028	Belongs to the TPP enzyme family
BWK49_RS20955	COG2259	Doxx family
BWK49_RS20970	COG1192	Involved in chromosome partitioning
BWK49_RS20975	COG0205	6-phosphofructokinase activity
BWK49_RS21030	COG0626	cystathionine gamma-synthase activity
BWK49_RS21080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BWK49_RS21130	COG0142	geranyltranstransferase activity
BWK49_RS21160	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BWK49_RS21200	COG1819	glycosyl
BWK49_RS21205	COG1304	FMN binding
BWK49_RS21210	COG2409	Drug exporters of the RND superfamily
BWK49_RS21220	COG0415	Belongs to the DNA photolyase family
BWK49_RS21230	COG0110	maltose O-acetyltransferase activity
BWK49_RS21235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWK49_RS21260	COG1024	Enoyl-CoA hydratase
BWK49_RS21270	COG1119	ATPase activity
BWK49_RS21280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWK49_RS21310	COG1309	transcriptional regulator
BWK49_RS21320	COG2072	flavoprotein involved in K transport
BWK49_RS21325	COG1309	transcriptional regulator
BWK49_RS21395	COG2186	Transcriptional regulator
BWK49_RS21410	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS21420	COG1793	dna ligase
BWK49_RS21425	COG0443	Heat shock 70 kDa protein
BWK49_RS21435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS21440	COG0183	Belongs to the thiolase family
BWK49_RS21445	COG1024	Enoyl-CoA hydratase
BWK49_RS21450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS21475	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS21490	COG2076	Multidrug Resistance protein
BWK49_RS21540	COG4638	Rieske (2fe-2S)
BWK49_RS21545	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS21570	COG4638	Rieske (2fe-2S)
BWK49_RS21595	COG3654	unkown
BWK49_RS21615	COG0477	Major facilitator Superfamily
BWK49_RS21625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWK49_RS21630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWK49_RS21650	COG2301	Belongs to the HpcH HpaI aldolase family
BWK49_RS21665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BWK49_RS21755	COG4638	Rieske (2fe-2S)
BWK49_RS21765	COG0842	Transport permease protein
BWK49_RS21765	COG1131	(ABC) transporter
BWK49_RS21765	COG1716	ATPase activity
BWK49_RS21775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWK49_RS21775	COG2755	lipolytic protein G-D-S-L family
BWK49_RS21820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BWK49_RS21825	COG2177	Part of the ABC transporter FtsEX involved in
BWK49_RS21830	COG2884	Cell division ATP-binding protein ftsE
BWK49_RS21840	COG0668	transmembrane transport
BWK49_RS21850	COG0493	'glutamate synthase
BWK49_RS21915	COG0483	inositol monophosphate 1-phosphatase activity
BWK49_RS21925	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS21930	COG0604	alcohol dehydrogenase
BWK49_RS21950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS21955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWK49_RS21965	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS21980	COG2353	YceI-like domain
BWK49_RS22000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWK49_RS22020	COG1034	ATP synthesis coupled electron transport
BWK49_RS22025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BWK49_RS22040	COG0713	ATP synthesis coupled electron transport
BWK49_RS22070	COG0714	Associated with various cellular activities
BWK49_RS22125	COG0297	glycogen (starch) synthase activity
BWK49_RS22140	COG2201	protein-glutamate methylesterase activity
BWK49_RS22190	COG0651	ATP synthesis coupled electron transport
BWK49_RS22195	COG1006	Multisubunit Na H antiporter MnhC subunit
BWK49_RS22210	COG1320	monovalent cation:proton antiporter activity
BWK49_RS22215	COG2212	antiporter activity
BWK49_RS22235	COG0028	Belongs to the TPP enzyme family
BWK49_RS22240	COG1573	uracil-dna glycosylase
BWK49_RS22300	COG0789	Transcriptional regulator
BWK49_RS22310	COG3707	response regulator
BWK49_RS22320	COG2197	response regulator
BWK49_RS22375	COG0697	spore germination
BWK49_RS22385	COG0477	Major facilitator Superfamily
BWK49_RS22390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BWK49_RS22415	COG0386	Belongs to the glutathione peroxidase family
BWK49_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS22455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BWK49_RS22465	COG0783	Belongs to the Dps family
BWK49_RS22495	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BWK49_RS22530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS22535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS22570	COG4221	oxidoreductase activity
BWK49_RS22600	COG3480	Lon protease (S16) C-terminal proteolytic domain
BWK49_RS22615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BWK49_RS22640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWK49_RS22660	COG0596	Alpha beta hydrolase
BWK49_RS22705	COG0513	Belongs to the DEAD box helicase family
BWK49_RS22720	COG0406	alpha-ribazole phosphatase activity
BWK49_RS22755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BWK49_RS22780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWK49_RS22785	COG1063	alcohol dehydrogenase
BWK49_RS22800	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS22820	COG1403	HNH endonuclease
BWK49_RS22825	COG2135	peptidase activity
BWK49_RS22830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BWK49_RS22835	COG1162	GTPase activity
BWK49_RS22840	COG1733	regulation of RNA biosynthetic process
BWK49_RS22845	COG0183	Belongs to the thiolase family
BWK49_RS22855	COG1309	transcriptional regulator
BWK49_RS22890	COG2020	methyltransferase activity
BWK49_RS22895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWK49_RS22905	COG0653	protein targeting
BWK49_RS22910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWK49_RS22920	COG5401	PFAM Sporulation and spore germination
BWK49_RS22925	COG5000	phosphorelay sensor kinase activity
BWK49_RS22925	COG5002	protein histidine kinase activity
BWK49_RS22940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BWK49_RS22960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWK49_RS22965	COG0531	amino acid
BWK49_RS22970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWK49_RS22975	COG1482	cell wall glycoprotein biosynthetic process
BWK49_RS22985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWK49_RS23030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BWK49_RS23045	COG1316	TRANSCRIPTIONal
BWK49_RS23070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS23075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS23115	COG0784	Response regulator, receiver
BWK49_RS23120	COG4251	negative regulation of phosphorylation
BWK49_RS23140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BWK49_RS23160	COG1053	succinate dehydrogenase
BWK49_RS23165	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS23180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWK49_RS23190	COG0424	maF-like protein
BWK49_RS23205	COG4770	biotin carboxylase activity
BWK49_RS23210	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS23240	COG1522	sequence-specific DNA binding
BWK49_RS23250	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS23255	COG1309	transcriptional regulator
BWK49_RS23260	COG1201	RNA secondary structure unwinding
BWK49_RS23300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BWK49_RS23315	COG0564	pseudouridine synthase activity
BWK49_RS23320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWK49_RS23340	COG1473	amidohydrolase
BWK49_RS23340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BWK49_RS23345	COG1473	amidohydrolase
BWK49_RS23365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWK49_RS23370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWK49_RS23375	COG3511	phospholipase C
BWK49_RS23385	COG2304	oxidoreductase activity
BWK49_RS23390	COG2304	oxidoreductase activity
BWK49_RS23425	COG2009	succinate dehydrogenase
BWK49_RS23435	COG1053	succinate dehydrogenase
BWK49_RS23440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWK49_RS23455	COG1595	DNA-templated transcription, initiation
BWK49_RS23460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWK49_RS23470	COG1686	Belongs to the peptidase S11 family
BWK49_RS23475	COG2814	Major facilitator Superfamily
BWK49_RS23490	COG1295	ribonuclease BN
BWK49_RS23515	COG2873	o-acetylhomoserine
BWK49_RS23535	COG1403	HNH endonuclease
BWK49_RS23560	COG1131	(ABC) transporter
BWK49_RS23560	COG0842	Transport permease protein
BWK49_RS23560	COG1716	ATPase activity
BWK49_RS23565	COG1131	(ABC) transporter
BWK49_RS23565	COG1716	ATPase activity
BWK49_RS23565	COG0842	Transport permease protein
BWK49_RS23570	COG1357	PFAM Pentapeptide repeats (8 copies)
BWK49_RS23585	COG2018	Roadblock/LC7 domain
BWK49_RS23590	COG5002	protein histidine kinase activity
BWK49_RS23600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWK49_RS23610	COG0587	DNA-directed DNA polymerase activity
BWK49_RS23615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWK49_RS23615	COG1877	trehalose-phosphatase activity
BWK49_RS23620	COG2030	dehydratase
BWK49_RS23625	COG0406	alpha-ribazole phosphatase activity
BWK49_RS23630	COG4221	oxidoreductase activity
BWK49_RS23635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS23655	COG0028	Belongs to the TPP enzyme family
BWK49_RS23660	COG0247	lactate metabolic process
BWK49_RS23660	COG0277	FAD linked oxidase domain protein
BWK49_RS23685	COG2124	cytochrome p450
BWK49_RS23700	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS23725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BWK49_RS23725	COG0519	Catalyzes the synthesis of GMP from XMP
BWK49_RS23810	COG2032	superoxide dismutase activity
BWK49_RS23830	COG0459	protein refolding
BWK49_RS23845	COG0456	acetyltransferase
BWK49_RS23850	COG0456	acetyltransferase
BWK49_RS23850	COG1214	PFAM Peptidase M22, glycoprotease
BWK49_RS23855	COG0802	atpase or kinase
BWK49_RS23870	COG0076	glutamate decarboxylase activity
BWK49_RS23890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BWK49_RS23915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS23945	COG4842	Belongs to the WXG100 family
BWK49_RS23950	COG4842	Belongs to the WXG100 family
BWK49_RS23960	COG1674	ftsk spoiiie
BWK49_RS23970	COG1404	Belongs to the peptidase S8 family
BWK49_RS24010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWK49_RS24015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWK49_RS24020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWK49_RS24025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWK49_RS24085	COG3794	PFAM blue (type 1) copper domain protein
BWK49_RS24110	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS24140	COG0563	adenylate kinase activity
BWK49_RS24150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS24160	COG1070	Carbohydrate kinase
BWK49_RS24180	COG1063	alcohol dehydrogenase
BWK49_RS24185	COG4221	oxidoreductase activity
BWK49_RS24205	COG0616	signal peptide processing
BWK49_RS24210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS24225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BWK49_RS24230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BWK49_RS24255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BWK49_RS24265	COG1403	HNH endonuclease
BWK49_RS24270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BWK49_RS24280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BWK49_RS24320	COG0088	Forms part of the polypeptide exit tunnel
BWK49_RS24345	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BWK49_RS24370	COG0535	radical SAM domain protein
BWK49_RS24395	COG0483	inositol monophosphate 1-phosphatase activity
BWK49_RS24405	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS24430	COG0049	tRNA binding
BWK49_RS24440	COG1309	transcriptional regulator
BWK49_RS24455	COG1024	Enoyl-CoA hydratase
BWK49_RS24470	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS24510	COG0222	ribosome binding
BWK49_RS24545	COG2318	DinB family
BWK49_RS24560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS24565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS24575	COG4941	Belongs to the sigma-70 factor family
BWK49_RS24595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWK49_RS24605	COG2030	dehydratase
BWK49_RS24610	COG2030	dehydratase
BWK49_RS24615	COG2030	dehydratase
BWK49_RS24640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWK49_RS24655	COG0243	molybdopterin cofactor binding
BWK49_RS24665	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWK49_RS24680	COG0778	Nitroreductase
BWK49_RS24685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS24690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BWK49_RS24695	COG1074	ATP-dependent DNA helicase activity
BWK49_RS24725	COG3537	Alpha-1,2-mannosidase
BWK49_RS24745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BWK49_RS24790	COG1914	H( )-stimulated, divalent metal cation uptake system
BWK49_RS24815	COG2072	flavoprotein involved in K transport
BWK49_RS24825	COG0659	secondary active sulfate transmembrane transporter activity
BWK49_RS24835	COG0501	Belongs to the peptidase M48B family
BWK49_RS24840	COG0142	geranyltranstransferase activity
BWK49_RS24855	COG2226	methyltransferase
BWK49_RS24875	COG3347	Dehydrogenase
BWK49_RS24875	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS24880	COG3618	amidohydrolase
BWK49_RS24925	COG1309	transcriptional regulator
BWK49_RS24950	COG1024	Enoyl-CoA hydratase
BWK49_RS24955	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS24975	COG2072	flavoprotein involved in K transport
BWK49_RS24980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWK49_RS25005	COG4948	Mandelate Racemase Muconate Lactonizing
BWK49_RS25010	COG1228	amidohydrolase
BWK49_RS25025	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS25035	COG0667	Aldo Keto reductase
BWK49_RS25050	COG4221	oxidoreductase activity
BWK49_RS25105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWK49_RS25110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BWK49_RS25135	COG2894	cell division
BWK49_RS25140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWK49_RS25150	COG0785	Cytochrome C biogenesis protein
BWK49_RS25160	COG0406	alpha-ribazole phosphatase activity
BWK49_RS25180	COG4948	Mandelate Racemase Muconate Lactonizing
BWK49_RS25185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWK49_RS25195	COG1113	amino acid transport
BWK49_RS25205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS25220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWK49_RS25220	COG2755	lipolytic protein G-D-S-L family
BWK49_RS25225	COG2755	lipolytic protein G-D-S-L family
BWK49_RS25235	COG1366	Belongs to the anti-sigma-factor antagonist family
BWK49_RS25300	COG2030	dehydratase
BWK49_RS25370	COG0588	phosphoglycerate mutase activity
BWK49_RS25380	COG0438	transferase activity, transferring glycosyl groups
BWK49_RS25425	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BWK49_RS25450	COG2733	membrane
BWK49_RS25465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWK49_RS25530	COG1505	serine-type exopeptidase activity
BWK49_RS25540	COG1024	Enoyl-CoA hydratase
BWK49_RS25550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWK49_RS25595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWK49_RS25615	COG4221	oxidoreductase activity
BWK49_RS25645	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS25655	COG0738	Major facilitator superfamily
BWK49_RS25670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWK49_RS25720	COG2032	superoxide dismutase activity
BWK49_RS25735	COG0242	peptide deformylase activity
BWK49_RS25765	COG3707	response regulator
BWK49_RS25830	COG1088	dTDP-glucose 4,6-dehydratase activity
BWK49_RS25835	COG2234	aminopeptidase activity
BWK49_RS25840	COG2234	aminopeptidase activity
BWK49_RS25880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWK49_RS25880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BWK49_RS25900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWK49_RS25915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWK49_RS25930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWK49_RS25950	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS25955	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS25980	COG1252	NADH dehydrogenase
BWK49_RS25990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWK49_RS26010	COG0406	alpha-ribazole phosphatase activity
BWK49_RS26020	COG1994	Peptidase M50
BWK49_RS26090	COG0542	response to heat
BWK49_RS26110	COG0789	Transcriptional regulator
BWK49_RS26115	COG0484	heat shock protein binding
BWK49_RS26120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BWK49_RS26155	COG2814	Major facilitator Superfamily
BWK49_RS26170	COG2181	nitrate reductase activity
BWK49_RS26170	COG0247	lactate metabolic process
BWK49_RS26200	COG2226	methyltransferase
BWK49_RS26205	COG0477	Major facilitator Superfamily
BWK49_RS26210	COG2175	clavaminate synthase activity
BWK49_RS26215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWK49_RS26255	COG1376	ErfK ybiS ycfS ynhG family protein
BWK49_RS26280	COG0246	Mannitol dehydrogenase
BWK49_RS26285	COG1070	Carbohydrate kinase
BWK49_RS26325	COG2130	NADP-dependent
BWK49_RS26390	COG0778	Nitroreductase
BWK49_RS26395	COG1368	sulfuric ester hydrolase activity
BWK49_RS26415	COG1404	Belongs to the peptidase S8 family
BWK49_RS26465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS26470	COG0254	rRNA binding
BWK49_RS26485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWK49_RS26490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BWK49_RS26495	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BWK49_RS26535	COG0346	lactoylglutathione lyase activity
BWK49_RS26550	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS26565	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS26575	COG2223	nitrite transmembrane transporter activity
BWK49_RS26605	COG1984	allophanate hydrolase subunit 2
BWK49_RS26640	COG2146	nitrite reductase [NAD(P)H] activity
BWK49_RS26640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWK49_RS26650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWK49_RS26665	COG1053	succinate dehydrogenase
BWK49_RS26690	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS26705	COG0183	Belongs to the thiolase family
BWK49_RS26715	COG2030	dehydratase
BWK49_RS26730	COG1472	Belongs to the glycosyl hydrolase 3 family
BWK49_RS26745	COG4981	capsule polysaccharide biosynthetic process
BWK49_RS26755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWK49_RS26800	COG1271	oxidase subunit
BWK49_RS26805	COG1294	oxidase, subunit
BWK49_RS26860	COG0028	Belongs to the TPP enzyme family
BWK49_RS26865	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS26870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWK49_RS26920	COG0297	glycogen (starch) synthase activity
BWK49_RS26925	COG0586	Pfam SNARE associated Golgi protein
BWK49_RS26945	COG1309	transcriptional regulator
BWK49_RS26955	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS26970	COG1024	Enoyl-CoA hydratase
BWK49_RS26980	COG0657	acetylesterase activity
BWK49_RS26990	COG2267	carboxylic ester hydrolase activity
BWK49_RS26995	COG0657	acetylesterase activity
BWK49_RS27000	COG1228	amidohydrolase
BWK49_RS27025	COG1024	Enoyl-CoA hydratase
BWK49_RS27035	COG2199	diguanylate cyclase activity
BWK49_RS27035	COG2203	Gaf domain
BWK49_RS27040	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BWK49_RS27065	COG2409	Drug exporters of the RND superfamily
BWK49_RS27105	COG3590	peptidase
BWK49_RS27110	COG0243	molybdopterin cofactor binding
BWK49_RS27120	COG1376	ErfK ybiS ycfS ynhG family protein
BWK49_RS27125	COG2814	Major facilitator Superfamily
BWK49_RS27130	COG1937	Protein conserved in bacteria
BWK49_RS27135	COG0129	dihydroxy-acid dehydratase activity
BWK49_RS27150	COG4122	O-methyltransferase activity
BWK49_RS27160	COG1472	Belongs to the glycosyl hydrolase 3 family
BWK49_RS27175	COG2267	carboxylic ester hydrolase activity
BWK49_RS27215	COG3619	membrane
BWK49_RS27230	COG1714	RDD family
BWK49_RS27245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWK49_RS27270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS27275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWK49_RS27285	COG1802	Transcriptional regulator
BWK49_RS27305	COG0657	acetylesterase activity
BWK49_RS27330	COG1063	alcohol dehydrogenase
BWK49_RS27335	COG2124	cytochrome p450
BWK49_RS27355	COG4221	oxidoreductase activity
BWK49_RS27365	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS27370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS27400	COG0277	FAD linked oxidase domain protein
BWK49_RS27420	COG1309	transcriptional regulator
BWK49_RS27450	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS27455	COG2365	Tyrosine phosphatase family
BWK49_RS27460	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS27465	COG1012	belongs to the aldehyde dehydrogenase family
BWK49_RS27490	COG1741	Belongs to the pirin family
BWK49_RS27495	COG0783	Belongs to the Dps family
BWK49_RS27515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWK49_RS27530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWK49_RS27545	COG3585	molybdate ion transport
BWK49_RS27550	COG0596	Alpha beta hydrolase
BWK49_RS27570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS27605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWK49_RS27615	COG3546	catalase activity
BWK49_RS27630	COG2267	carboxylic ester hydrolase activity
BWK49_RS27650	COG1937	Protein conserved in bacteria
BWK49_RS27675	COG0842	Transport permease protein
BWK49_RS27675	COG1129	ABC transporter
BWK49_RS27695	COG3281	Trehalose synthase
BWK49_RS27705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWK49_RS27725	COG0028	Belongs to the TPP enzyme family
BWK49_RS27730	COG0583	DNA-binding transcription factor activity
BWK49_RS27735	COG1376	ErfK ybiS ycfS ynhG family protein
BWK49_RS27765	COG2755	lipolytic protein G-D-S-L family
BWK49_RS27765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWK49_RS27775	COG0028	Belongs to the TPP enzyme family
BWK49_RS27780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS27785	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS27790	COG2072	flavoprotein involved in K transport
BWK49_RS27800	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS27805	COG3386	PFAM SMP-30 Gluconolaconase
BWK49_RS27815	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS27825	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS27885	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BWK49_RS27905	COG2226	methyltransferase
BWK49_RS27915	COG0300	oxidoreductase activity
BWK49_RS27955	COG1063	alcohol dehydrogenase
BWK49_RS27975	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS27995	COG2072	flavoprotein involved in K transport
BWK49_RS28020	COG0583	DNA-binding transcription factor activity
BWK49_RS28025	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS28040	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS28045	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS28060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BWK49_RS28080	COG1309	transcriptional regulator
BWK49_RS28090	COG1028	Short-chain dehydrogenase reductase Sdr
BWK49_RS28095	COG0318	PFAM AMP-dependent synthetase and ligase
BWK49_RS28120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BWK49_RS28145	COG1960	acyl-CoA dehydrogenase activity
BWK49_RS28150	COG1309	transcriptional regulator
BWK49_RS28175	COG3588	fructose-bisphosphate aldolase
BWK49_RS28210	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWK49_RS28215	COG4638	Rieske (2fe-2S)
BWK49_RS28225	COG2197	response regulator
BWK49_RS28230	COG4585	Histidine kinase
BWK49_RS28245	COG1674	ftsk spoiiie
BWK49_RS28295	COG0617	tRNA 3'-terminal CCA addition
BWK49_RS28325	COG1595	DNA-templated transcription, initiation
BWK49_RS28345	COG3409	Peptidoglycan-binding domain 1 protein
BWK49_RS28345	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWK49_RS28360	COG1192	Involved in chromosome partitioning
BWK49_RS28365	COG0357	Ribosomal RNA small subunit methyltransferase G
BWK49_RS28375	COG0706	membrane insertase activity
BWK49_RS28380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BWK49_RS28425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWK49_RS28440	COG0640	Transcriptional regulator
BWK49_RS28460	COG2801	Transposase and inactivated derivatives
BWK49_RS28585	COG2337	Toxic component of a toxin-antitoxin (TA) module
BWK49_RS28640	COG2161	toxin-antitoxin pair type II binding
BWK49_RS28645	COG2026	Addiction module toxin, RelE StbE family
BWK49_RS28660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWK49_RS28785	COG4974	Belongs to the 'phage' integrase family
BWK49_RS28935	COG3328	transposase activity
BWK49_RS28970	COG1674	ftsk spoiiie
BWK49_RS29010	COG1404	Belongs to the peptidase S8 family
BWK49_RS29230	COG2801	Transposase and inactivated derivatives
BWK49_RS29340	COG1090	epimerase
BWK49_RS29580	COG3510	cephalosporin hydroxylase
BWK49_RS29815	COG0305	Participates in initiation and elongation during chromosome replication
BWK49_RS29850	COG1388	LysM domain