locus-tag	class	description
CE197_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CE197_RS00010	COG0592	DNA-directed DNA polymerase activity
CE197_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CE197_RS00025	COG0187	DNA topoisomerase II activity
CE197_RS00050	COG3177	Filamentation induced by cAMP protein fic
CE197_RS00090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CE197_RS00120	COG0515	serine threonine protein kinase
CE197_RS00145	COG1716	ATPase activity
CE197_RS00170	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS00280	COG0495	leucyl-tRNA aminoacylation
CE197_RS00295	COG1126	abc transporter atp-binding protein
CE197_RS00300	COG0765	amino acid transport
CE197_RS00310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS00325	COG1309	transcriptional regulator
CE197_RS00330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CE197_RS00330	COG0596	Alpha beta hydrolase
CE197_RS00375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CE197_RS00390	COG0360	Binds together with S18 to 16S ribosomal RNA
CE197_RS00415	COG1309	transcriptional regulator
CE197_RS00430	COG1278	Cold shock
CE197_RS00440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE197_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS00475	COG0778	Nitroreductase
CE197_RS00475	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CE197_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS00550	COG0277	FAD linked oxidase domain protein
CE197_RS00565	COG2267	carboxylic ester hydrolase activity
CE197_RS00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS00610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS00655	COG1309	transcriptional regulator
CE197_RS00710	COG0659	secondary active sulfate transmembrane transporter activity
CE197_RS00720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CE197_RS00730	COG2124	cytochrome p450
CE197_RS00740	COG0714	Associated with various cellular activities
CE197_RS00760	COG0477	Major facilitator Superfamily
CE197_RS00780	COG0346	lactoylglutathione lyase activity
CE197_RS00795	COG0494	nUDIX hydrolase
CE197_RS00820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS00840	COG4552	Acetyltransferase involved in intracellular survival and related
CE197_RS00845	COG1960	acyl-CoA dehydrogenase activity
CE197_RS00850	COG1309	transcriptional regulator
CE197_RS00865	COG5651	PPE family
CE197_RS00920	COG0702	epimerase
CE197_RS00945	COG0070	glutamate synthase
CE197_RS00945	COG0067	glutamate synthase
CE197_RS00945	COG0069	glutamate synthase activity
CE197_RS00970	COG1796	DNA polymerase
CE197_RS00970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CE197_RS00980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CE197_RS00990	COG2072	flavoprotein involved in K transport
CE197_RS01035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CE197_RS01050	COG1316	TRANSCRIPTIONal
CE197_RS01140	COG0561	phosphatase activity
CE197_RS01160	COG1216	Glycosyl transferase, family 2
CE197_RS01175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CE197_RS01185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CE197_RS01190	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CE197_RS01195	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS01200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE197_RS01200	COG3321	synthase
CE197_RS01200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CE197_RS01205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE197_RS01210	COG1960	acyl-CoA dehydrogenase activity
CE197_RS01250	COG0640	Transcriptional regulator
CE197_RS01265	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS01270	COG0277	FAD linked oxidase domain protein
CE197_RS01285	COG1403	HNH endonuclease
CE197_RS01290	COG2801	Transposase and inactivated derivatives
CE197_RS01325	COG0604	alcohol dehydrogenase
CE197_RS01345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CE197_RS01365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CE197_RS01410	COG0745	RESPONSE REGULATOR receiver
CE197_RS01415	COG2205	protein histidine kinase activity
CE197_RS01425	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CE197_RS01470	COG5416	Lipopolysaccharide assembly protein A domain
CE197_RS01485	COG1174	glycine betaine transport
CE197_RS01500	COG0287	Prephenate dehydrogenase
CE197_RS01510	COG0590	tRNA wobble adenosine to inosine editing
CE197_RS01585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS01590	COG2301	Belongs to the HpcH HpaI aldolase family
CE197_RS01595	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CE197_RS01605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CE197_RS01615	COG3800	Transcriptional regulator
CE197_RS01615	COG1396	sequence-specific DNA binding
CE197_RS01620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE197_RS01625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CE197_RS01645	COG3804	dihydrodipicolinate reductase
CE197_RS01665	COG0596	Alpha beta hydrolase
CE197_RS01670	COG2124	cytochrome p450
CE197_RS01690	COG1793	dna ligase
CE197_RS01705	COG1335	isochorismatase
CE197_RS01740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CE197_RS01765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CE197_RS01775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS01790	COG0860	N-Acetylmuramoyl-L-alanine amidase
CE197_RS01795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CE197_RS01815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CE197_RS01820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CE197_RS01865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CE197_RS01870	COG0121	glutamine amidotransferase
CE197_RS01880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CE197_RS01895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CE197_RS01900	COG1695	Transcriptional regulator
CE197_RS01925	COG0714	Associated with various cellular activities
CE197_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS01960	COG0693	protein deglycase activity
CE197_RS01965	COG2890	protein-(glutamine-N5) methyltransferase activity
CE197_RS01990	COG2172	sigma factor antagonist activity
CE197_RS01995	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS02000	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS02015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE197_RS02040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS02045	COG1408	metallophosphoesterase
CE197_RS02080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE197_RS02095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CE197_RS02130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CE197_RS02150	COG0601	transmembrane transport
CE197_RS02155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CE197_RS02225	COG1205	dead DEAH box helicase
CE197_RS02225	COG1111	helicase
CE197_RS02250	COG0470	DNA polymerase III
CE197_RS02295	COG2027	D-alanyl-D-alanine carboxypeptidase
CE197_RS02305	COG0037	tRNA processing
CE197_RS02330	COG0657	acetylesterase activity
CE197_RS02345	COG3344	reverse transcriptase
CE197_RS02430	COG2072	flavoprotein involved in K transport
CE197_RS02435	COG1309	transcriptional regulator
CE197_RS02495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE197_RS02510	COG2801	Transposase and inactivated derivatives
CE197_RS02515	COG1063	alcohol dehydrogenase
CE197_RS02525	COG2267	carboxylic ester hydrolase activity
CE197_RS02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CE197_RS02545	COG0302	gtp cyclohydrolase
CE197_RS02550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CE197_RS02555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CE197_RS02580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CE197_RS02595	COG2801	Transposase and inactivated derivatives
CE197_RS02595	COG3415	Transposase
CE197_RS02665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CE197_RS02700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CE197_RS02710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CE197_RS02715	COG1121	(ABC) transporter
CE197_RS02725	COG1609	Transcriptional regulator
CE197_RS02730	COG1309	transcriptional regulator
CE197_RS02735	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02785	COG0436	Aminotransferase
CE197_RS02790	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02795	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02800	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02805	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS02810	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02825	COG0183	Belongs to the thiolase family
CE197_RS02860	COG1024	Enoyl-CoA hydratase
CE197_RS02865	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS02870	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS02890	COG0183	Belongs to the thiolase family
CE197_RS02895	COG2124	cytochrome p450
CE197_RS02900	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02905	COG1960	acyl-CoA dehydrogenase activity
CE197_RS02910	COG2030	dehydratase
CE197_RS02930	COG2030	dehydratase
CE197_RS02935	COG1053	succinate dehydrogenase
CE197_RS02940	COG3971	2-oxopent-4-enoate hydratase activity
CE197_RS02945	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CE197_RS02950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CE197_RS02965	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS02980	COG4638	Rieske (2fe-2S)
CE197_RS03010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS03020	COG2124	cytochrome p450
CE197_RS03040	COG3001	Fructosamine kinase
CE197_RS03050	COG0028	Belongs to the TPP enzyme family
CE197_RS03065	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS03070	COG1960	acyl-CoA dehydrogenase activity
CE197_RS03075	COG1960	acyl-CoA dehydrogenase activity
CE197_RS03085	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS03090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS03120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE197_RS03155	COG1024	Enoyl-CoA hydratase
CE197_RS03170	COG1316	TRANSCRIPTIONal
CE197_RS03250	COG0745	RESPONSE REGULATOR receiver
CE197_RS03255	COG2205	protein histidine kinase activity
CE197_RS03285	COG2124	cytochrome p450
CE197_RS03290	COG4221	oxidoreductase activity
CE197_RS03325	COG1716	ATPase activity
CE197_RS03355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CE197_RS03375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CE197_RS03385	COG0477	Major facilitator Superfamily
CE197_RS03390	COG0477	Major facilitator Superfamily
CE197_RS03405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CE197_RS03415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CE197_RS03420	COG0047	phosphoribosylformylglycinamidine synthase activity
CE197_RS03430	COG0204	Acyl-transferase
CE197_RS03485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CE197_RS03485	COG1017	nitric oxide dioxygenase activity
CE197_RS03495	COG2837	iron assimilation
CE197_RS03545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CE197_RS03600	COG0745	RESPONSE REGULATOR receiver
CE197_RS03625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CE197_RS03670	COG0640	Transcriptional regulator
CE197_RS03675	COG0590	tRNA wobble adenosine to inosine editing
CE197_RS03705	COG4974	Belongs to the 'phage' integrase family
CE197_RS03725	COG1609	Transcriptional regulator
CE197_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS03795	COG2124	cytochrome p450
CE197_RS03800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CE197_RS03805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS03825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CE197_RS03825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CE197_RS03830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CE197_RS03835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS03840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS03875	COG1960	acyl-CoA dehydrogenase activity
CE197_RS03880	COG1960	acyl-CoA dehydrogenase activity
CE197_RS03890	COG2267	carboxylic ester hydrolase activity
CE197_RS03895	COG3479	Phenolic acid decarboxylase
CE197_RS03905	COG1703	isobutyryl-CoA mutase activity
CE197_RS03910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CE197_RS03920	COG4585	Histidine kinase
CE197_RS03930	COG0504	CTP synthase activity
CE197_RS03935	COG1053	succinate dehydrogenase
CE197_RS03945	COG2267	carboxylic ester hydrolase activity
CE197_RS03950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS03955	COG3384	dioxygenase
CE197_RS03960	COG1053	succinate dehydrogenase
CE197_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS03985	COG2132	Multicopper oxidase
CE197_RS04000	COG2197	response regulator
CE197_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS04060	COG1024	Enoyl-CoA hydratase
CE197_RS04065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS04075	COG3415	Transposase
CE197_RS04075	COG2801	Transposase and inactivated derivatives
CE197_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS04095	COG1960	acyl-CoA dehydrogenase activity
CE197_RS04110	COG1960	acyl-CoA dehydrogenase activity
CE197_RS04120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CE197_RS04130	COG4638	Rieske (2fe-2S)
CE197_RS04150	COG1024	Enoyl-CoA hydratase
CE197_RS04155	COG0183	Belongs to the thiolase family
CE197_RS04160	COG1309	transcriptional regulator
CE197_RS04190	COG2124	cytochrome p450
CE197_RS04235	COG1960	acyl-CoA dehydrogenase activity
CE197_RS04245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CE197_RS04285	COG1960	acyl-CoA dehydrogenase activity
CE197_RS04290	COG1960	acyl-CoA dehydrogenase activity
CE197_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS04335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS04340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS04365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE197_RS04400	COG1309	transcriptional regulator
CE197_RS04445	COG1024	Enoyl-CoA hydratase
CE197_RS04460	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS04505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS04525	COG0183	Belongs to the thiolase family
CE197_RS04530	COG1024	Enoyl-CoA hydratase
CE197_RS04530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CE197_RS04535	COG2813	Specifically methylates the guanine in position
CE197_RS04555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS04585	COG1061	Type III restriction enzyme res subunit
CE197_RS04625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CE197_RS04630	COG3304	Inner membrane component domain
CE197_RS04635	COG1278	Cold shock
CE197_RS04645	COG0435	Glutathione S-transferase
CE197_RS04660	COG2814	Major facilitator Superfamily
CE197_RS04700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CE197_RS04725	COG0259	pyridoxamine-phosphate oxidase activity
CE197_RS04860	COG2267	carboxylic ester hydrolase activity
CE197_RS04875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS04920	COG0581	inorganic phosphate transmembrane transporter activity
CE197_RS04945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS04980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CE197_RS05010	COG4942	peptidase
CE197_RS05050	COG0138	bifunctional purine biosynthesis protein purh
CE197_RS05070	COG0656	L-ascorbic acid biosynthetic process
CE197_RS05080	COG1024	Enoyl-CoA hydratase
CE197_RS05095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE197_RS05100	COG1960	acyl-CoA dehydrogenase activity
CE197_RS05130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CE197_RS05135	COG0521	Mo-molybdopterin cofactor biosynthetic process
CE197_RS05135	COG0315	cyclic pyranopterin monophosphate synthase activity
CE197_RS05140	COG1970	mechanosensitive ion channel activity
CE197_RS05155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CE197_RS05160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CE197_RS05195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS05225	COG1024	Enoyl-CoA hydratase
CE197_RS05250	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CE197_RS05255	COG0131	Imidazoleglycerol-phosphate dehydratase
CE197_RS05255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CE197_RS05260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE197_RS05260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CE197_RS05295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CE197_RS05305	COG1252	NADH dehydrogenase
CE197_RS05340	COG0438	transferase activity, transferring glycosyl groups
CE197_RS05340	COG0297	glycogen (starch) synthase activity
CE197_RS05380	COG0297	glycogen (starch) synthase activity
CE197_RS05395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CE197_RS05445	COG0084	hydrolase, TatD family'
CE197_RS05460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CE197_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS05475	COG0193	aminoacyl-tRNA hydrolase activity
CE197_RS05480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CE197_RS05525	COG1309	transcriptional regulator
CE197_RS05545	COG3956	TIGRFAM MazG family protein
CE197_RS05590	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CE197_RS05595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CE197_RS05615	COG2205	protein histidine kinase activity
CE197_RS05620	COG0745	RESPONSE REGULATOR receiver
CE197_RS05675	COG3391	amine dehydrogenase activity
CE197_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS05695	COG0121	glutamine amidotransferase
CE197_RS05740	COG1024	Enoyl-CoA hydratase
CE197_RS05750	COG0183	Belongs to the thiolase family
CE197_RS05755	COG2755	lipolytic protein G-D-S-L family
CE197_RS05760	COG0657	acetylesterase activity
CE197_RS05800	COG1331	Highly conserved protein containing a thioredoxin domain
CE197_RS05815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CE197_RS05825	COG0572	uridine kinase
CE197_RS05845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CE197_RS05895	COG2272	Belongs to the type-B carboxylesterase lipase family
CE197_RS05910	COG1570	exodeoxyribonuclease VII activity
CE197_RS05920	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CE197_RS05930	COG0012	GTP binding
CE197_RS05940	COG2161	toxin-antitoxin pair type II binding
CE197_RS05945	COG2026	Addiction module toxin, RelE StbE family
CE197_RS05990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS06015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CE197_RS06045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CE197_RS06045	COG0574	Belongs to the PEP-utilizing enzyme family
CE197_RS06080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CE197_RS06085	COG0702	epimerase
CE197_RS06095	COG1309	transcriptional regulator
CE197_RS06105	COG1960	acyl-CoA dehydrogenase activity
CE197_RS06110	COG1960	acyl-CoA dehydrogenase activity
CE197_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS06130	COG0714	Associated with various cellular activities
CE197_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS06150	COG2124	cytochrome p450
CE197_RS06155	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS06160	COG0183	Belongs to the thiolase family
CE197_RS06165	COG1024	Enoyl-CoA hydratase
CE197_RS06175	COG1755	Isoprenylcysteine carboxyl methyltransferase
CE197_RS06185	COG0702	epimerase
CE197_RS06195	COG0702	epimerase
CE197_RS06200	COG1024	Enoyl-CoA hydratase
CE197_RS06205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS06220	COG2409	Drug exporters of the RND superfamily
CE197_RS06230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CE197_RS06245	COG3467	pyridoxamine 5'-phosphate
CE197_RS06305	COG1140	nitrate reductase beta subunit
CE197_RS06320	COG1217	gtp-binding protein TYPA
CE197_RS06335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CE197_RS06345	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CE197_RS06360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CE197_RS06370	COG0531	amino acid
CE197_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS06375	COG0604	alcohol dehydrogenase
CE197_RS06375	COG3321	synthase
CE197_RS06390	COG0529	Catalyzes the synthesis of activated sulfate
CE197_RS06395	COG2046	Belongs to the sulfate adenylyltransferase family
CE197_RS06410	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS06425	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS06430	COG0506	proline dehydrogenase activity
CE197_RS06435	COG1309	transcriptional regulator
CE197_RS06460	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS06470	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS06475	COG0477	Major facilitator Superfamily
CE197_RS06505	COG1611	Belongs to the LOG family
CE197_RS06510	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS06520	COG0463	Glycosyl transferase, family 2
CE197_RS06530	COG0519	Catalyzes the synthesis of GMP from XMP
CE197_RS06545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CE197_RS06555	COG3559	Exporter of polyketide antibiotics
CE197_RS06560	COG1131	(ABC) transporter
CE197_RS06565	COG1309	transcriptional regulator
CE197_RS06580	COG5662	AntiSigma factor
CE197_RS06585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CE197_RS06610	COG2239	Acts as a magnesium transporter
CE197_RS06655	COG0598	Magnesium transport protein CorA
CE197_RS06660	COG0039	L-malate dehydrogenase activity
CE197_RS06730	COG0277	FAD linked oxidase domain protein
CE197_RS06745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS06895	COG3631	Ketosteroid isomerase-related protein
CE197_RS06900	COG0494	nUDIX hydrolase
CE197_RS06925	COG0018	arginyl-trna synthetase
CE197_RS06930	COG0019	diaminopimelate decarboxylase activity
CE197_RS06935	COG0460	homoserine dehydrogenase
CE197_RS06945	COG0083	homoserine kinase activity
CE197_RS06955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CE197_RS06970	COG2890	protein-(glutamine-N5) methyltransferase activity
CE197_RS06990	COG0356	it plays a direct role in the translocation of protons across the membrane
CE197_RS06995	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CE197_RS07005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CE197_RS07005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CE197_RS07040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CE197_RS07060	COG5651	PPE family
CE197_RS07065	COG3391	amine dehydrogenase activity
CE197_RS07085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CE197_RS07105	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CE197_RS07130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CE197_RS07140	COG0058	SHG alpha-glucan phosphorylase activity
CE197_RS07150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CE197_RS07175	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CE197_RS07180	COG1234	tRNA 3'-trailer cleavage
CE197_RS07185	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CE197_RS07190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CE197_RS07215	COG3011	Protein conserved in bacteria
CE197_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS07245	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07255	COG0183	Belongs to the thiolase family
CE197_RS07260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS07265	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07270	COG1802	Transcriptional regulator
CE197_RS07290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CE197_RS07295	COG1024	Enoyl-CoA hydratase
CE197_RS07300	COG1024	Enoyl-CoA hydratase
CE197_RS07305	COG1024	Enoyl-CoA hydratase
CE197_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS07330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CE197_RS07340	COG1024	Enoyl-CoA hydratase
CE197_RS07365	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07375	COG0183	Belongs to the thiolase family
CE197_RS07440	COG2072	flavoprotein involved in K transport
CE197_RS07460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE197_RS07475	COG1309	transcriptional regulator
CE197_RS07495	COG2124	cytochrome p450
CE197_RS07500	COG0657	acetylesterase activity
CE197_RS07505	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07510	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07535	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07540	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07545	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07550	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07580	COG2124	cytochrome p450
CE197_RS07620	COG4638	Rieske (2fe-2S)
CE197_RS07635	COG3757	hydrolase, family 25
CE197_RS07650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE197_RS07650	COG3321	synthase
CE197_RS07650	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CE197_RS07655	COG0736	holo-[acyl-carrier-protein] synthase activity
CE197_RS07700	COG4552	Acetyltransferase involved in intracellular survival and related
CE197_RS07705	COG2409	Drug exporters of the RND superfamily
CE197_RS07710	COG0697	spore germination
CE197_RS07715	COG1376	ErfK ybiS ycfS ynhG family protein
CE197_RS07745	COG0300	oxidoreductase activity
CE197_RS07765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE197_RS07775	COG1960	acyl-CoA dehydrogenase activity
CE197_RS07780	COG2030	dehydratase
CE197_RS07800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CE197_RS07820	COG0657	acetylesterase activity
CE197_RS07835	COG2937	Belongs to the GPAT DAPAT family
CE197_RS07845	COG4115	mRNA cleavage
CE197_RS07855	COG0629	single-stranded DNA binding
CE197_RS07865	COG2902	Dehydrogenase
CE197_RS07885	COG0366	Alpha amylase catalytic
CE197_RS07890	COG2346	COG2346, Truncated hemoglobins
CE197_RS07915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CE197_RS07920	COG0698	ribose 5-phosphate isomerase
CE197_RS07935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CE197_RS07955	COG0740	serine-type endopeptidase activity
CE197_RS07960	COG0740	serine-type endopeptidase activity
CE197_RS07965	COG2040	homocysteine
CE197_RS07980	COG0674	pyruvate-flavodoxin oxidoreductase activity
CE197_RS07980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CE197_RS07985	COG1013	pyruvate-flavodoxin oxidoreductase activity
CE197_RS08000	COG1388	LysM domain
CE197_RS08005	COG3268	Saccharopine dehydrogenase
CE197_RS08010	COG0525	valine-tRNA ligase activity
CE197_RS08015	COG0285	dihydrofolate synthase activity
CE197_RS08025	COG0105	UTP biosynthetic process
CE197_RS08030	COG1530	ribonuclease E activity
CE197_RS08045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CE197_RS08075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CE197_RS08075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CE197_RS08080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE197_RS08085	COG5002	protein histidine kinase activity
CE197_RS08090	COG0668	transmembrane transport
CE197_RS08095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CE197_RS08100	COG0542	response to heat
CE197_RS08110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CE197_RS08115	COG0799	negative regulation of ribosome biogenesis
CE197_RS08125	COG2755	lipolytic protein G-D-S-L family
CE197_RS08150	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS08155	COG5651	PPE family
CE197_RS08160	COG2409	Drug exporters of the RND superfamily
CE197_RS08185	COG1960	acyl-CoA dehydrogenase activity
CE197_RS08190	COG1960	acyl-CoA dehydrogenase activity
CE197_RS08195	COG1596	polysaccharide export
CE197_RS08195	COG1555	photosystem II stabilization
CE197_RS08200	COG2333	competence protein COMEC
CE197_RS08200	COG0658	competence protein
CE197_RS08225	COG1305	Transglutaminase-like
CE197_RS08235	COG1234	tRNA 3'-trailer cleavage
CE197_RS08240	COG0517	IMP dehydrogenase activity
CE197_RS08250	COG0481	GTPase activity
CE197_RS08265	COG3387	PFAM Glycoside hydrolase 15-related
CE197_RS08275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CE197_RS08280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CE197_RS08285	COG4208	sulfate ABC transporter
CE197_RS08290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CE197_RS08300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CE197_RS08325	COG1169	isochorismate synthase
CE197_RS08335	COG2072	flavoprotein involved in K transport
CE197_RS08395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CE197_RS08445	COG3321	synthase
CE197_RS08445	COG0604	alcohol dehydrogenase
CE197_RS08460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE197_RS08470	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CE197_RS08470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE197_RS08480	COG3415	Transposase
CE197_RS08480	COG2801	Transposase and inactivated derivatives
CE197_RS08500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS08525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CE197_RS08570	COG3344	reverse transcriptase
CE197_RS08585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE197_RS08590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CE197_RS08605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CE197_RS08625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS08640	COG0657	acetylesterase activity
CE197_RS08695	COG2132	Multicopper oxidase
CE197_RS08720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS08730	COG0019	diaminopimelate decarboxylase activity
CE197_RS08760	COG0640	Transcriptional regulator
CE197_RS08765	COG1937	Protein conserved in bacteria
CE197_RS08835	COG2124	cytochrome p450
CE197_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS08885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS08895	COG1063	alcohol dehydrogenase
CE197_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS08935	COG1309	transcriptional regulator
CE197_RS08950	COG1960	acyl-CoA dehydrogenase activity
CE197_RS08965	COG1960	acyl-CoA dehydrogenase activity
CE197_RS08985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS09015	COG1960	acyl-CoA dehydrogenase activity
CE197_RS09030	COG1960	acyl-CoA dehydrogenase activity
CE197_RS09035	COG1960	acyl-CoA dehydrogenase activity
CE197_RS09040	COG1021	2,3-dihydroxybenzoate-AMP ligase
CE197_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS09075	COG1024	Enoyl-CoA hydratase
CE197_RS09085	COG1960	acyl-CoA dehydrogenase activity
CE197_RS09090	COG1024	Enoyl-CoA hydratase
CE197_RS09100	COG1024	Enoyl-CoA hydratase
CE197_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS09110	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS09140	COG1024	Enoyl-CoA hydratase
CE197_RS09155	COG1960	acyl-CoA dehydrogenase activity
CE197_RS09170	COG1024	Enoyl-CoA hydratase
CE197_RS09200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE197_RS09240	COG1937	Protein conserved in bacteria
CE197_RS09245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE197_RS09340	COG4948	Mandelate Racemase Muconate Lactonizing
CE197_RS09345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CE197_RS09380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CE197_RS09385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE197_RS09465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CE197_RS09480	COG1309	transcriptional regulator
CE197_RS09485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CE197_RS09490	COG1021	2,3-dihydroxybenzoate-AMP ligase
CE197_RS09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE197_RS09510	COG3321	synthase
CE197_RS09510	COG0604	alcohol dehydrogenase
CE197_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE197_RS09525	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CE197_RS09545	COG1595	DNA-templated transcription, initiation
CE197_RS09560	COG1420	regulation of RNA biosynthetic process
CE197_RS09565	COG0484	heat shock protein binding
CE197_RS09600	COG1982	Orn Lys Arg decarboxylase major
CE197_RS09610	COG1381	Involved in DNA repair and RecF pathway recombination
CE197_RS09635	COG0423	glycine-tRNA ligase activity
CE197_RS09680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS09685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS09695	COG1045	serine acetyltransferase
CE197_RS09705	COG2855	membrane
CE197_RS09710	COG4424	Sulfotransferase
CE197_RS09720	COG0243	molybdopterin cofactor binding
CE197_RS09735	COG1131	(ABC) transporter
CE197_RS09735	COG0842	Transport permease protein
CE197_RS09735	COG1716	ATPase activity
CE197_RS09765	COG0531	amino acid
CE197_RS09780	COG1175	transmembrane transport
CE197_RS09895	COG1309	transcriptional regulator
CE197_RS09900	COG2267	carboxylic ester hydrolase activity
CE197_RS09935	COG4638	Rieske (2fe-2S)
CE197_RS09940	COG0596	Alpha beta hydrolase
CE197_RS09950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CE197_RS09965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS09980	COG4638	Rieske (2fe-2S)
CE197_RS09990	COG0515	serine threonine protein kinase
CE197_RS09990	COG2815	serine threonine protein kinase
CE197_RS10015	COG1141	Ferredoxin
CE197_RS10020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS10025	COG1309	transcriptional regulator
CE197_RS10030	COG2124	cytochrome p450
CE197_RS10040	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS10045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS10095	COG2208	phosphoserine phosphatase activity
CE197_RS10095	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS10095	COG2172	sigma factor antagonist activity
CE197_RS10115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS10120	COG2226	methyltransferase
CE197_RS10200	COG2132	Multicopper oxidase
CE197_RS10220	COG0596	Alpha beta hydrolase
CE197_RS10235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CE197_RS10245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CE197_RS10250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS10265	COG2124	cytochrome p450
CE197_RS10270	COG2267	carboxylic ester hydrolase activity
CE197_RS10285	COG0798	PFAM Bile acid sodium symporter
CE197_RS10320	COG0438	transferase activity, transferring glycosyl groups
CE197_RS10335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CE197_RS10350	COG0657	acetylesterase activity
CE197_RS10360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CE197_RS10375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CE197_RS10395	COG1309	transcriptional regulator
CE197_RS10450	COG1487	ribonuclease activity
CE197_RS10490	COG1960	acyl-CoA dehydrogenase activity
CE197_RS10495	COG0860	N-Acetylmuramoyl-L-alanine amidase
CE197_RS10510	COG2072	flavoprotein involved in K transport
CE197_RS10625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CE197_RS10670	COG0596	Alpha beta hydrolase
CE197_RS10675	COG0346	lactoylglutathione lyase activity
CE197_RS10680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CE197_RS10835	COG0321	lipoyl(octanoyl) transferase activity
CE197_RS10870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CE197_RS10880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CE197_RS10885	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CE197_RS10890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CE197_RS10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CE197_RS10930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CE197_RS10965	COG1845	cytochrome c oxidase, subunit III
CE197_RS11000	COG1022	Amp-dependent synthetase and ligase
CE197_RS11015	COG0003	Pfam Anion-transporting ATPase
CE197_RS11045	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CE197_RS11065	COG0142	geranyltranstransferase activity
CE197_RS11105	COG0768	penicillin binding
CE197_RS11150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CE197_RS11170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CE197_RS11215	COG1484	DNA-dependent DNA replication
CE197_RS11220	COG4584	PFAM Integrase catalytic
CE197_RS11445	COG2072	flavoprotein involved in K transport
CE197_RS11495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS11500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS11525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE197_RS11605	COG2072	flavoprotein involved in K transport
CE197_RS11620	COG2072	flavoprotein involved in K transport
CE197_RS11635	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS11685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CE197_RS11695	COG0167	dihydroorotate dehydrogenase activity
CE197_RS11730	COG1218	3'(2'),5'-bisphosphate nucleotidase
CE197_RS11735	COG0215	cysteine-tRNA ligase activity
CE197_RS11770	COG0604	alcohol dehydrogenase
CE197_RS11770	COG3321	synthase
CE197_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS11775	COG2124	cytochrome p450
CE197_RS11790	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS11810	COG0646	methionine synthase
CE197_RS11810	COG1410	methionine synthase
CE197_RS11855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS11940	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CE197_RS12015	COG0300	oxidoreductase activity
CE197_RS12060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CE197_RS12095	COG0412	Dienelactone hydrolase
CE197_RS12130	COG0604	alcohol dehydrogenase
CE197_RS12130	COG3321	synthase
CE197_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS12170	COG0714	Associated with various cellular activities
CE197_RS12205	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS12230	COG2272	Belongs to the type-B carboxylesterase lipase family
CE197_RS12240	COG3265	gluconokinase activity
CE197_RS12260	COG1335	isochorismatase
CE197_RS12275	COG1595	DNA-templated transcription, initiation
CE197_RS12285	COG1175	transmembrane transport
CE197_RS12290	COG0395	ABC-type sugar transport system, permease component
CE197_RS12295	COG3842	ATPase activity
CE197_RS12300	COG1752	Esterase of the alpha-beta hydrolase superfamily
CE197_RS12325	COG2837	iron assimilation
CE197_RS12335	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CE197_RS12365	COG0667	Aldo Keto reductase
CE197_RS12375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CE197_RS12395	COG1960	acyl-CoA dehydrogenase activity
CE197_RS12485	COG1022	Amp-dependent synthetase and ligase
CE197_RS12660	COG0523	cobalamin synthesis protein
CE197_RS12665	COG1946	Acyl-CoA thioesterase
CE197_RS12715	COG3621	Patatin-like phospholipase
CE197_RS12735	COG2226	methyltransferase
CE197_RS12785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CE197_RS12790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CE197_RS12795	COG0713	ATP synthesis coupled electron transport
CE197_RS12805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CE197_RS12895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS12950	COG2132	Multicopper oxidase
CE197_RS12985	COG1937	Protein conserved in bacteria
CE197_RS12995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS13010	COG0019	diaminopimelate decarboxylase activity
CE197_RS13015	COG0534	Mate efflux family protein
CE197_RS13020	COG2226	methyltransferase
CE197_RS13035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CE197_RS13040	COG0798	PFAM Bile acid sodium symporter
CE197_RS13045	COG2226	methyltransferase
CE197_RS13050	COG0640	Transcriptional regulator
CE197_RS13080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS13095	COG5651	PPE family
CE197_RS13120	COG0789	Transcriptional regulator
CE197_RS13170	COG1309	transcriptional regulator
CE197_RS13220	COG2161	toxin-antitoxin pair type II binding
CE197_RS13255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS13275	COG1595	DNA-templated transcription, initiation
CE197_RS13310	COG2204	response regulator
CE197_RS13340	COG1116	anion transmembrane transporter activity
CE197_RS13355	COG0583	DNA-binding transcription factor activity
CE197_RS13385	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
CE197_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS13415	COG2301	Belongs to the HpcH HpaI aldolase family
CE197_RS13425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CE197_RS13435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS13440	COG1643	Atp-dependent helicase
CE197_RS13450	COG1024	Enoyl-CoA hydratase
CE197_RS13470	COG1063	alcohol dehydrogenase
CE197_RS13520	COG0723	plastoquinol--plastocyanin reductase activity
CE197_RS13520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE197_RS13530	COG1376	ErfK ybiS ycfS ynhG family protein
CE197_RS13545	COG3757	hydrolase, family 25
CE197_RS13550	COG0438	transferase activity, transferring glycosyl groups
CE197_RS13555	COG2226	methyltransferase
CE197_RS13575	COG1309	transcriptional regulator
CE197_RS13590	COG3391	amine dehydrogenase activity
CE197_RS13600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS13660	COG4977	sequence-specific DNA binding
CE197_RS13675	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS13685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CE197_RS13720	COG0640	Transcriptional regulator
CE197_RS13740	COG1233	COG1233 Phytoene dehydrogenase and related
CE197_RS13750	COG1942	4-Oxalocrotonate Tautomerase
CE197_RS13785	COG1950	PFAM Membrane protein of
CE197_RS13790	COG1403	HNH endonuclease
CE197_RS13800	COG2814	Major facilitator Superfamily
CE197_RS13805	COG1546	Belongs to the CinA family
CE197_RS13805	COG1058	Belongs to the CinA family
CE197_RS13835	COG1063	alcohol dehydrogenase
CE197_RS13845	COG2070	2-Nitropropane dioxygenase
CE197_RS13890	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CE197_RS13935	COG0174	glutamine synthetase
CE197_RS13945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CE197_RS13955	COG2193	ferroxidase activity
CE197_RS13965	COG1024	Enoyl-CoA hydratase
CE197_RS13990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CE197_RS14055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS14060	COG1968	undecaprenyl-diphosphatase activity
CE197_RS14065	COG4221	oxidoreductase activity
CE197_RS14130	COG1252	NADH dehydrogenase
CE197_RS14155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CE197_RS14170	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS14175	COG1960	acyl-CoA dehydrogenase activity
CE197_RS14180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE197_RS14185	COG1253	flavin adenine dinucleotide binding
CE197_RS14190	COG1253	flavin adenine dinucleotide binding
CE197_RS14285	COG1053	succinate dehydrogenase
CE197_RS14285	COG3976	FMN-binding domain protein
CE197_RS14325	COG5651	PPE family
CE197_RS14375	COG1404	Belongs to the peptidase S8 family
CE197_RS14405	COG5651	PPE family
CE197_RS14425	COG5651	PPE family
CE197_RS14430	COG0657	acetylesterase activity
CE197_RS14435	COG5651	PPE family
CE197_RS14475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CE197_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS14525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CE197_RS14530	COG0022	dehydrogenase e1 component
CE197_RS14540	COG1024	Enoyl-CoA hydratase
CE197_RS14545	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS14550	COG4638	Rieske (2fe-2S)
CE197_RS14555	COG1053	succinate dehydrogenase
CE197_RS14590	COG2813	Specifically methylates the guanine in position
CE197_RS14650	COG4221	oxidoreductase activity
CE197_RS14690	COG4221	oxidoreductase activity
CE197_RS14695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS14700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CE197_RS14705	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS14730	COG2226	methyltransferase
CE197_RS14745	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS14765	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS14795	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS14800	COG2072	flavoprotein involved in K transport
CE197_RS14820	COG2030	dehydratase
CE197_RS14825	COG1960	acyl-CoA dehydrogenase activity
CE197_RS14830	COG1960	acyl-CoA dehydrogenase activity
CE197_RS14835	COG0842	Transport permease protein
CE197_RS14835	COG1716	ATPase activity
CE197_RS14835	COG1131	(ABC) transporter
CE197_RS14840	COG0657	acetylesterase activity
CE197_RS14845	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS14850	COG0243	molybdopterin cofactor binding
CE197_RS14870	COG2267	carboxylic ester hydrolase activity
CE197_RS14895	COG2072	flavoprotein involved in K transport
CE197_RS14910	COG0346	lactoylglutathione lyase activity
CE197_RS14925	COG0657	acetylesterase activity
CE197_RS14950	COG2072	flavoprotein involved in K transport
CE197_RS14955	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS14960	COG1063	alcohol dehydrogenase
CE197_RS14970	COG1024	Enoyl-CoA hydratase
CE197_RS14975	COG1960	acyl-CoA dehydrogenase activity
CE197_RS14995	COG0657	acetylesterase activity
CE197_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS15030	COG1053	succinate dehydrogenase
CE197_RS15095	COG2271	Major facilitator Superfamily
CE197_RS15100	COG0189	ligase activity
CE197_RS15100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CE197_RS15130	COG1305	Transglutaminase-like
CE197_RS15140	COG1278	Cold shock
CE197_RS15150	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS15210	COG0789	Transcriptional regulator
CE197_RS15285	COG2239	Acts as a magnesium transporter
CE197_RS15305	COG2132	Multicopper oxidase
CE197_RS15310	COG2226	methyltransferase
CE197_RS15320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS15410	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CE197_RS15410	COG1672	PFAM Archaeal ATPase
CE197_RS15430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CE197_RS15440	COG0713	ATP synthesis coupled electron transport
CE197_RS15445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CE197_RS15475	COG5002	protein histidine kinase activity
CE197_RS15485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS15535	COG0508	dehydrogenase complex catalyzes the overall conversion of
CE197_RS15535	COG0596	Alpha beta hydrolase
CE197_RS15550	COG0745	RESPONSE REGULATOR receiver
CE197_RS15555	COG2205	protein histidine kinase activity
CE197_RS15565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CE197_RS15585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CE197_RS15600	COG0604	alcohol dehydrogenase
CE197_RS15600	COG3321	synthase
CE197_RS15630	COG1937	Protein conserved in bacteria
CE197_RS15640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS15650	COG0019	diaminopimelate decarboxylase activity
CE197_RS15680	COG4584	PFAM Integrase catalytic
CE197_RS15685	COG2161	toxin-antitoxin pair type II binding
CE197_RS15705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CE197_RS15755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CE197_RS15765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CE197_RS15770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CE197_RS15790	COG0494	nUDIX hydrolase
CE197_RS15815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CE197_RS15830	COG0647	UMP catabolic process
CE197_RS15845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CE197_RS15850	COG2094	Belongs to the DNA glycosylase MPG family
CE197_RS15860	COG1131	(ABC) transporter
CE197_RS15875	COG1309	transcriptional regulator
CE197_RS15880	COG2835	tetraacyldisaccharide 4'-kinase activity
CE197_RS15910	COG0300	oxidoreductase activity
CE197_RS15915	COG4948	Mandelate Racemase Muconate Lactonizing
CE197_RS15920	COG3707	response regulator
CE197_RS15925	COG0488	(ABC) transporter
CE197_RS15940	COG3321	synthase
CE197_RS15940	COG0604	alcohol dehydrogenase
CE197_RS15940	COG0604	alcohol dehydrogenase
CE197_RS15940	COG3321	synthase
CE197_RS15945	COG0604	alcohol dehydrogenase
CE197_RS15945	COG3321	synthase
CE197_RS15950	COG0604	alcohol dehydrogenase
CE197_RS15950	COG3321	synthase
CE197_RS15960	COG0165	Argininosuccinate lyase
CE197_RS15975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CE197_RS15990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CE197_RS15995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CE197_RS16000	COG0072	phenylalanine-tRNA ligase activity
CE197_RS16000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CE197_RS16005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CE197_RS16035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CE197_RS16060	COG1309	transcriptional regulator
CE197_RS16070	COG2890	protein-(glutamine-N5) methyltransferase activity
CE197_RS16145	COG0842	Transport permease protein
CE197_RS16145	COG1131	(ABC) transporter
CE197_RS16145	COG1716	ATPase activity
CE197_RS16175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CE197_RS16190	COG0237	dephospho-CoA kinase activity
CE197_RS16190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CE197_RS16200	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CE197_RS16245	COG1271	oxidase subunit
CE197_RS16250	COG1294	oxidase, subunit
CE197_RS16255	COG4988	ABC transporter
CE197_RS16260	COG1132	(ABC) transporter
CE197_RS16275	COG1946	Acyl-CoA thioesterase
CE197_RS16315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CE197_RS16325	COG0387	Pfam Sodium calcium exchanger
CE197_RS16330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CE197_RS16340	COG0483	inositol monophosphate 1-phosphatase activity
CE197_RS16350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CE197_RS16355	COG0131	Imidazoleglycerol-phosphate dehydratase
CE197_RS16365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CE197_RS16375	COG0157	Belongs to the NadC ModD family
CE197_RS16465	COG3883	PFAM NLP P60 protein
CE197_RS16465	COG0791	NLP P60 protein
CE197_RS16500	COG0671	phosphoesterase, PA-phosphatase related
CE197_RS16530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS16555	COG0300	oxidoreductase activity
CE197_RS16565	COG2346	COG2346, Truncated hemoglobins
CE197_RS16585	COG0252	asparaginase activity
CE197_RS16595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CE197_RS16605	COG2070	2-Nitropropane dioxygenase
CE197_RS16690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CE197_RS16695	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CE197_RS16720	COG4221	oxidoreductase activity
CE197_RS16770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CE197_RS16875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CE197_RS16890	COG2304	oxidoreductase activity
CE197_RS16900	COG0714	Associated with various cellular activities
CE197_RS16910	COG0791	NLP P60 protein
CE197_RS16910	COG3883	PFAM NLP P60 protein
CE197_RS16920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CE197_RS16925	COG1309	transcriptional regulator
CE197_RS16935	COG0488	(ABC) transporter
CE197_RS16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CE197_RS16950	COG1960	acyl-CoA dehydrogenase activity
CE197_RS16980	COG0251	oxidation-reduction process
CE197_RS17005	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS17100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CE197_RS17115	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS17125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CE197_RS17150	COG2151	metal-sulfur cluster biosynthetic enzyme
CE197_RS17155	COG0822	iron-sulfur transferase activity
CE197_RS17165	COG0396	ATPase activity
CE197_RS17190	COG1131	(ABC) transporter
CE197_RS17225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CE197_RS17250	COG0123	including yeast histone deacetylase and acetoin utilization protein
CE197_RS17255	COG0667	Aldo Keto reductase
CE197_RS17260	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CE197_RS17300	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS17305	COG0657	acetylesterase activity
CE197_RS17310	COG1403	HNH endonuclease
CE197_RS17330	COG1660	Displays ATPase and GTPase activities
CE197_RS17335	COG0322	excinuclease ABC activity
CE197_RS17365	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CE197_RS17430	COG0657	acetylesterase activity
CE197_RS17460	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CE197_RS17485	COG0505	Belongs to the CarA family
CE197_RS17505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CE197_RS17515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CE197_RS17545	COG2188	Transcriptional regulator
CE197_RS17585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CE197_RS17615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CE197_RS17620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CE197_RS17625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CE197_RS17635	COG0432	Pfam Uncharacterised protein family UPF0047
CE197_RS17700	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CE197_RS17720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CE197_RS17725	COG0235	Class ii aldolase
CE197_RS17730	COG1396	sequence-specific DNA binding
CE197_RS17765	COG1403	HNH endonuclease
CE197_RS17805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS17820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CE197_RS17860	COG1914	H( )-stimulated, divalent metal cation uptake system
CE197_RS17865	COG5651	PPE family
CE197_RS17895	COG3344	reverse transcriptase
CE197_RS17900	COG3415	Transposase
CE197_RS17900	COG2801	Transposase and inactivated derivatives
CE197_RS17920	COG2239	Acts as a magnesium transporter
CE197_RS18025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CE197_RS18035	COG0124	histidyl-tRNA synthetase
CE197_RS18055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CE197_RS18060	COG0747	negative chemotaxis
CE197_RS18065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CE197_RS18090	COG3320	Male sterility
CE197_RS18090	COG1022	Amp-dependent synthetase and ligase
CE197_RS18140	COG3766	membrane
CE197_RS18160	COG1946	Acyl-CoA thioesterase
CE197_RS18215	COG0667	Aldo Keto reductase
CE197_RS18220	COG4762	Protein conserved in bacteria
CE197_RS18235	COG2070	2-Nitropropane dioxygenase
CE197_RS18275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CE197_RS18285	COG3485	protocatechuate 3,4-dioxygenase
CE197_RS18325	COG1414	Transcriptional regulator
CE197_RS18335	COG1309	transcriptional regulator
CE197_RS18340	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS18345	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CE197_RS18355	COG0753	catalase activity
CE197_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS18380	COG1024	Enoyl-CoA hydratase
CE197_RS18585	COG1511	domain protein
CE197_RS18610	COG4689	acetoacetate decarboxylase
CE197_RS18645	COG1309	transcriptional regulator
CE197_RS18665	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS18725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CE197_RS18730	COG2264	protein methyltransferase activity
CE197_RS18735	COG3253	May function as heme-dependent peroxidase
CE197_RS18775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CE197_RS18800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CE197_RS18805	COG0531	amino acid
CE197_RS18810	COG0569	domain protein
CE197_RS18860	COG0483	inositol monophosphate 1-phosphatase activity
CE197_RS18955	COG1388	LysM domain
CE197_RS18970	COG1960	acyl-CoA dehydrogenase activity
CE197_RS18975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CE197_RS18985	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CE197_RS19000	COG1196	nuclear chromosome segregation
CE197_RS19010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CE197_RS19050	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
CE197_RS19065	COG1842	Phage shock protein A
CE197_RS19080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CE197_RS19110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CE197_RS19120	COG3214	Protein conserved in bacteria
CE197_RS19145	COG1960	acyl-CoA dehydrogenase activity
CE197_RS19150	COG1960	acyl-CoA dehydrogenase activity
CE197_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS19190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CE197_RS19195	COG1403	HNH endonuclease
CE197_RS19250	COG0686	Belongs to the AlaDH PNT family
CE197_RS19265	COG1185	polyribonucleotide nucleotidyltransferase activity
CE197_RS19295	COG1960	acyl-CoA dehydrogenase activity
CE197_RS19300	COG0183	Belongs to the thiolase family
CE197_RS19305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CE197_RS19310	COG2977	Belongs to the P-Pant transferase superfamily
CE197_RS19315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CE197_RS19350	COG0534	Mate efflux family protein
CE197_RS19355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CE197_RS19365	COG0481	GTPase activity
CE197_RS19410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CE197_RS19410	COG1648	precorrin-2 dehydrogenase activity
CE197_RS19435	COG0579	oxidoreductase
CE197_RS19455	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CE197_RS19460	COG0375	protein maturation
CE197_RS19510	COG0298	carbon dioxide binding
CE197_RS19525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CE197_RS19530	COG0309	Hydrogenase expression formation protein (HypE)
CE197_RS19550	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CE197_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS19575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CE197_RS19590	COG1492	cobalamin metabolic process
CE197_RS19615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CE197_RS19620	COG0750	zinc metalloprotease
CE197_RS19625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CE197_RS19645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CE197_RS19650	COG0575	Belongs to the CDS family
CE197_RS19670	COG0745	RESPONSE REGULATOR receiver
CE197_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS19705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CE197_RS19730	COG0154	amidase activity
CE197_RS19740	COG0052	Belongs to the universal ribosomal protein uS2 family
CE197_RS19785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CE197_RS19795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CE197_RS19810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CE197_RS19830	COG0336	Belongs to the RNA methyltransferase TrmD family
CE197_RS19835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CE197_RS19845	COG0228	four-way junction DNA binding
CE197_RS19855	COG1686	Belongs to the peptidase S11 family
CE197_RS19900	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CE197_RS19920	COG1196	nuclear chromosome segregation
CE197_RS19935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CE197_RS19945	COG0571	ribonuclease III activity
CE197_RS19960	COG0701	Predicted permease
CE197_RS19985	COG0742	ribosomal rna small subunit methyltransferase
CE197_RS20000	COG0657	acetylesterase activity
CE197_RS20020	COG1461	Dihydroxyacetone kinase
CE197_RS20065	COG3321	synthase
CE197_RS20065	COG0604	alcohol dehydrogenase
CE197_RS20085	COG1181	Belongs to the D-alanine--D-alanine ligase family
CE197_RS20090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CE197_RS20095	COG1920	GTP binding
CE197_RS20100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CE197_RS20145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CE197_RS20150	COG0179	Fumarylacetoacetate (FAA) hydrolase
CE197_RS20155	COG2271	Major facilitator Superfamily
CE197_RS20160	COG2271	Major facilitator Superfamily
CE197_RS20165	COG0473	3-isopropylmalate dehydrogenase activity
CE197_RS20180	COG0655	NAD(P)H dehydrogenase (quinone) activity
CE197_RS20195	COG0028	Belongs to the TPP enzyme family
CE197_RS20205	COG2259	Doxx family
CE197_RS20220	COG1192	Involved in chromosome partitioning
CE197_RS20225	COG0205	6-phosphofructokinase activity
CE197_RS20280	COG0626	cystathionine gamma-synthase activity
CE197_RS20330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CE197_RS20380	COG0142	geranyltranstransferase activity
CE197_RS20410	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CE197_RS20450	COG1819	glycosyl
CE197_RS20455	COG1304	FMN binding
CE197_RS20460	COG2409	Drug exporters of the RND superfamily
CE197_RS20470	COG0415	Belongs to the DNA photolyase family
CE197_RS20480	COG0110	maltose O-acetyltransferase activity
CE197_RS20485	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CE197_RS20510	COG1024	Enoyl-CoA hydratase
CE197_RS20520	COG1119	ATPase activity
CE197_RS20530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CE197_RS20560	COG1309	transcriptional regulator
CE197_RS20570	COG2072	flavoprotein involved in K transport
CE197_RS20575	COG1309	transcriptional regulator
CE197_RS20645	COG2186	Transcriptional regulator
CE197_RS20660	COG1960	acyl-CoA dehydrogenase activity
CE197_RS20670	COG1793	dna ligase
CE197_RS20675	COG0443	Heat shock 70 kDa protein
CE197_RS20685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS20690	COG0183	Belongs to the thiolase family
CE197_RS20695	COG1024	Enoyl-CoA hydratase
CE197_RS20700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS20725	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS20740	COG2076	Multidrug Resistance protein
CE197_RS20790	COG4638	Rieske (2fe-2S)
CE197_RS20795	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS20820	COG4638	Rieske (2fe-2S)
CE197_RS20845	COG3654	unkown
CE197_RS20865	COG0477	Major facilitator Superfamily
CE197_RS20875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CE197_RS20880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CE197_RS20900	COG2301	Belongs to the HpcH HpaI aldolase family
CE197_RS20915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CE197_RS21005	COG4638	Rieske (2fe-2S)
CE197_RS21020	COG0842	Transport permease protein
CE197_RS21020	COG1131	(ABC) transporter
CE197_RS21020	COG1716	ATPase activity
CE197_RS21030	COG2755	lipolytic protein G-D-S-L family
CE197_RS21030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CE197_RS21075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CE197_RS21080	COG2177	Part of the ABC transporter FtsEX involved in
CE197_RS21085	COG2884	Cell division ATP-binding protein ftsE
CE197_RS21095	COG0668	transmembrane transport
CE197_RS21105	COG0493	'glutamate synthase
CE197_RS21170	COG0483	inositol monophosphate 1-phosphatase activity
CE197_RS21180	COG1960	acyl-CoA dehydrogenase activity
CE197_RS21185	COG0604	alcohol dehydrogenase
CE197_RS21205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS21210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CE197_RS21220	COG1960	acyl-CoA dehydrogenase activity
CE197_RS21235	COG2353	YceI-like domain
CE197_RS21275	COG1034	ATP synthesis coupled electron transport
CE197_RS21280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CE197_RS21295	COG0713	ATP synthesis coupled electron transport
CE197_RS21325	COG0714	Associated with various cellular activities
CE197_RS21380	COG0297	glycogen (starch) synthase activity
CE197_RS21395	COG2201	protein-glutamate methylesterase activity
CE197_RS21440	COG3237	CsbD-like
CE197_RS21450	COG0651	ATP synthesis coupled electron transport
CE197_RS21455	COG1006	Multisubunit Na H antiporter MnhC subunit
CE197_RS21470	COG1320	monovalent cation:proton antiporter activity
CE197_RS21475	COG2212	antiporter activity
CE197_RS21495	COG0028	Belongs to the TPP enzyme family
CE197_RS21500	COG1573	uracil-dna glycosylase
CE197_RS21560	COG0789	Transcriptional regulator
CE197_RS21570	COG3707	response regulator
CE197_RS21635	COG0697	spore germination
CE197_RS21645	COG0477	Major facilitator Superfamily
CE197_RS21650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CE197_RS21675	COG0386	Belongs to the glutathione peroxidase family
CE197_RS21705	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS21715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CE197_RS21725	COG0783	Belongs to the Dps family
CE197_RS21765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CE197_RS21800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS21805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS21840	COG4221	oxidoreductase activity
CE197_RS21870	COG3480	Lon protease (S16) C-terminal proteolytic domain
CE197_RS21885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CE197_RS21910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CE197_RS21930	COG0596	Alpha beta hydrolase
CE197_RS21975	COG0513	Belongs to the DEAD box helicase family
CE197_RS21990	COG0406	alpha-ribazole phosphatase activity
CE197_RS22025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CE197_RS22050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CE197_RS22055	COG1063	alcohol dehydrogenase
CE197_RS22070	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS22080	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS22090	COG1403	HNH endonuclease
CE197_RS22095	COG2135	peptidase activity
CE197_RS22100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CE197_RS22105	COG1162	GTPase activity
CE197_RS22110	COG1733	regulation of RNA biosynthetic process
CE197_RS22115	COG0183	Belongs to the thiolase family
CE197_RS22125	COG1309	transcriptional regulator
CE197_RS22160	COG2020	methyltransferase activity
CE197_RS22165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CE197_RS22175	COG0653	protein targeting
CE197_RS22180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CE197_RS22190	COG5401	PFAM Sporulation and spore germination
CE197_RS22195	COG5002	protein histidine kinase activity
CE197_RS22195	COG5000	phosphorelay sensor kinase activity
CE197_RS22210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CE197_RS22230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CE197_RS22235	COG0531	amino acid
CE197_RS22240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS22245	COG1482	cell wall glycoprotein biosynthetic process
CE197_RS22255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CE197_RS22300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CE197_RS22315	COG1316	TRANSCRIPTIONal
CE197_RS22340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS22345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS22385	COG0784	Response regulator, receiver
CE197_RS22390	COG4251	negative regulation of phosphorylation
CE197_RS22410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CE197_RS22430	COG1053	succinate dehydrogenase
CE197_RS22435	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS22450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CE197_RS22460	COG0424	maF-like protein
CE197_RS22475	COG4770	biotin carboxylase activity
CE197_RS22480	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS22510	COG1522	sequence-specific DNA binding
CE197_RS22520	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS22525	COG1309	transcriptional regulator
CE197_RS22530	COG1201	RNA secondary structure unwinding
CE197_RS22570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CE197_RS22580	COG0564	pseudouridine synthase activity
CE197_RS22585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CE197_RS22600	COG0657	acetylesterase activity
CE197_RS22605	COG1473	amidohydrolase
CE197_RS22605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CE197_RS22610	COG1473	amidohydrolase
CE197_RS22625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CE197_RS22630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CE197_RS22635	COG3511	phospholipase C
CE197_RS22645	COG2304	oxidoreductase activity
CE197_RS22650	COG2304	oxidoreductase activity
CE197_RS22685	COG2009	succinate dehydrogenase
CE197_RS22695	COG1053	succinate dehydrogenase
CE197_RS22700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CE197_RS22715	COG1595	DNA-templated transcription, initiation
CE197_RS22725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CE197_RS22735	COG1686	Belongs to the peptidase S11 family
CE197_RS22740	COG2814	Major facilitator Superfamily
CE197_RS22755	COG1295	ribonuclease BN
CE197_RS22780	COG2873	o-acetylhomoserine
CE197_RS22830	COG1716	ATPase activity
CE197_RS22830	COG0842	Transport permease protein
CE197_RS22830	COG1131	(ABC) transporter
CE197_RS22835	COG1716	ATPase activity
CE197_RS22835	COG1131	(ABC) transporter
CE197_RS22835	COG0842	Transport permease protein
CE197_RS22840	COG1357	PFAM Pentapeptide repeats (8 copies)
CE197_RS22855	COG2018	Roadblock/LC7 domain
CE197_RS22860	COG5002	protein histidine kinase activity
CE197_RS22870	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CE197_RS22880	COG0587	DNA-directed DNA polymerase activity
CE197_RS22885	COG1877	trehalose-phosphatase activity
CE197_RS22885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CE197_RS22890	COG2030	dehydratase
CE197_RS22895	COG0406	alpha-ribazole phosphatase activity
CE197_RS22900	COG4221	oxidoreductase activity
CE197_RS22905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS22925	COG0028	Belongs to the TPP enzyme family
CE197_RS22930	COG0247	lactate metabolic process
CE197_RS22930	COG0277	FAD linked oxidase domain protein
CE197_RS22955	COG2124	cytochrome p450
CE197_RS22970	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS22995	COG0519	Catalyzes the synthesis of GMP from XMP
CE197_RS22995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CE197_RS23080	COG2032	superoxide dismutase activity
CE197_RS23100	COG0459	protein refolding
CE197_RS23115	COG0456	acetyltransferase
CE197_RS23120	COG0456	acetyltransferase
CE197_RS23120	COG1214	PFAM Peptidase M22, glycoprotease
CE197_RS23125	COG0802	atpase or kinase
CE197_RS23140	COG0076	glutamate decarboxylase activity
CE197_RS23160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CE197_RS23185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS23215	COG4842	Belongs to the WXG100 family
CE197_RS23220	COG4842	Belongs to the WXG100 family
CE197_RS23230	COG1674	ftsk spoiiie
CE197_RS23240	COG1404	Belongs to the peptidase S8 family
CE197_RS23280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CE197_RS23285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CE197_RS23290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CE197_RS23295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CE197_RS23305	COG2205	protein histidine kinase activity
CE197_RS23360	COG3794	PFAM blue (type 1) copper domain protein
CE197_RS23385	COG1960	acyl-CoA dehydrogenase activity
CE197_RS23400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CE197_RS23415	COG0028	Belongs to the TPP enzyme family
CE197_RS23420	COG0577	efflux transmembrane transporter activity
CE197_RS23420	COG1136	(ABC) transporter
CE197_RS23425	COG0577	efflux transmembrane transporter activity
CE197_RS23430	COG2226	methyltransferase
CE197_RS23440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CE197_RS23460	COG0563	adenylate kinase activity
CE197_RS23470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS23480	COG1070	Carbohydrate kinase
CE197_RS23500	COG1063	alcohol dehydrogenase
CE197_RS23505	COG4221	oxidoreductase activity
CE197_RS23525	COG0616	signal peptide processing
CE197_RS23530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS23545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CE197_RS23550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CE197_RS23575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CE197_RS23585	COG1403	HNH endonuclease
CE197_RS23595	COG1573	uracil-dna glycosylase
CE197_RS23610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CE197_RS23620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CE197_RS23660	COG0088	Forms part of the polypeptide exit tunnel
CE197_RS23685	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CE197_RS23710	COG0535	radical SAM domain protein
CE197_RS23735	COG0483	inositol monophosphate 1-phosphatase activity
CE197_RS23745	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS23770	COG0049	tRNA binding
CE197_RS23780	COG1309	transcriptional regulator
CE197_RS23795	COG1024	Enoyl-CoA hydratase
CE197_RS23810	COG1960	acyl-CoA dehydrogenase activity
CE197_RS23850	COG0222	ribosome binding
CE197_RS23885	COG2318	DinB family
CE197_RS23900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS23905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS23915	COG4941	Belongs to the sigma-70 factor family
CE197_RS23920	COG0081	regulation of translation
CE197_RS23935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CE197_RS23945	COG2030	dehydratase
CE197_RS23950	COG2030	dehydratase
CE197_RS23955	COG2030	dehydratase
CE197_RS23980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE197_RS23995	COG0243	molybdopterin cofactor binding
CE197_RS24005	COG1752	Esterase of the alpha-beta hydrolase superfamily
CE197_RS24020	COG0778	Nitroreductase
CE197_RS24025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS24030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CE197_RS24035	COG1074	ATP-dependent DNA helicase activity
CE197_RS24065	COG3537	Alpha-1,2-mannosidase
CE197_RS24085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CE197_RS24130	COG1914	H( )-stimulated, divalent metal cation uptake system
CE197_RS24155	COG2072	flavoprotein involved in K transport
CE197_RS24165	COG0659	secondary active sulfate transmembrane transporter activity
CE197_RS24175	COG0501	Belongs to the peptidase M48B family
CE197_RS24180	COG0142	geranyltranstransferase activity
CE197_RS24195	COG2226	methyltransferase
CE197_RS24200	COG4221	oxidoreductase activity
CE197_RS24225	COG4948	Mandelate Racemase Muconate Lactonizing
CE197_RS24230	COG1228	amidohydrolase
CE197_RS24255	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS24265	COG0667	Aldo Keto reductase
CE197_RS24280	COG4221	oxidoreductase activity
CE197_RS24335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CE197_RS24340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CE197_RS24365	COG2894	cell division
CE197_RS24370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CE197_RS24380	COG0785	Cytochrome C biogenesis protein
CE197_RS24390	COG0406	alpha-ribazole phosphatase activity
CE197_RS24410	COG4948	Mandelate Racemase Muconate Lactonizing
CE197_RS24415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CE197_RS24425	COG1113	amino acid transport
CE197_RS24435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS24450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CE197_RS24450	COG2755	lipolytic protein G-D-S-L family
CE197_RS24455	COG2755	lipolytic protein G-D-S-L family
CE197_RS24465	COG1366	Belongs to the anti-sigma-factor antagonist family
CE197_RS24530	COG2030	dehydratase
CE197_RS24600	COG0588	phosphoglycerate mutase activity
CE197_RS24610	COG0438	transferase activity, transferring glycosyl groups
CE197_RS24655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CE197_RS24680	COG2733	membrane
CE197_RS24695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CE197_RS24760	COG1505	serine-type exopeptidase activity
CE197_RS24770	COG1024	Enoyl-CoA hydratase
CE197_RS24780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CE197_RS24825	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CE197_RS24845	COG4221	oxidoreductase activity
CE197_RS24875	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS24885	COG0738	Major facilitator superfamily
CE197_RS24900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CE197_RS24950	COG2032	superoxide dismutase activity
CE197_RS24965	COG0242	peptide deformylase activity
CE197_RS24995	COG3707	response regulator
CE197_RS25065	COG1088	dTDP-glucose 4,6-dehydratase activity
CE197_RS25070	COG2234	aminopeptidase activity
CE197_RS25075	COG2234	aminopeptidase activity
CE197_RS25115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CE197_RS25115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CE197_RS25135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CE197_RS25150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CE197_RS25165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CE197_RS25185	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS25190	COG1960	acyl-CoA dehydrogenase activity
CE197_RS25210	COG1252	NADH dehydrogenase
CE197_RS25220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CE197_RS25240	COG0406	alpha-ribazole phosphatase activity
CE197_RS25250	COG1994	Peptidase M50
CE197_RS25320	COG0542	response to heat
CE197_RS25340	COG0789	Transcriptional regulator
CE197_RS25345	COG0484	heat shock protein binding
CE197_RS25350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CE197_RS25385	COG2814	Major facilitator Superfamily
CE197_RS25405	COG2181	nitrate reductase activity
CE197_RS25405	COG0247	lactate metabolic process
CE197_RS25435	COG2226	methyltransferase
CE197_RS25440	COG0477	Major facilitator Superfamily
CE197_RS25445	COG2175	clavaminate synthase activity
CE197_RS25450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CE197_RS25495	COG1376	ErfK ybiS ycfS ynhG family protein
CE197_RS25520	COG0246	Mannitol dehydrogenase
CE197_RS25525	COG1070	Carbohydrate kinase
CE197_RS25565	COG2130	NADP-dependent
CE197_RS25630	COG0778	Nitroreductase
CE197_RS25635	COG1368	sulfuric ester hydrolase activity
CE197_RS25655	COG1404	Belongs to the peptidase S8 family
CE197_RS25705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS25710	COG0254	rRNA binding
CE197_RS25725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CE197_RS25730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CE197_RS25735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CE197_RS25780	COG0346	lactoylglutathione lyase activity
CE197_RS25795	COG1960	acyl-CoA dehydrogenase activity
CE197_RS25810	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS25820	COG2223	nitrite transmembrane transporter activity
CE197_RS25850	COG1984	allophanate hydrolase subunit 2
CE197_RS25885	COG2146	nitrite reductase [NAD(P)H] activity
CE197_RS25885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CE197_RS25895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CE197_RS25910	COG1053	succinate dehydrogenase
CE197_RS25935	COG1960	acyl-CoA dehydrogenase activity
CE197_RS25950	COG0183	Belongs to the thiolase family
CE197_RS25955	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS25960	COG2030	dehydratase
CE197_RS25975	COG1472	Belongs to the glycosyl hydrolase 3 family
CE197_RS25990	COG4981	capsule polysaccharide biosynthetic process
CE197_RS26000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CE197_RS26060	COG0028	Belongs to the TPP enzyme family
CE197_RS26065	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS26070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CE197_RS26130	COG0586	Pfam SNARE associated Golgi protein
CE197_RS26150	COG1309	transcriptional regulator
CE197_RS26160	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS26175	COG1024	Enoyl-CoA hydratase
CE197_RS26185	COG0657	acetylesterase activity
CE197_RS26195	COG2267	carboxylic ester hydrolase activity
CE197_RS26205	COG1228	amidohydrolase
CE197_RS26230	COG1024	Enoyl-CoA hydratase
CE197_RS26240	COG2199	diguanylate cyclase activity
CE197_RS26240	COG2203	Gaf domain
CE197_RS26245	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CE197_RS26260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CE197_RS26270	COG2409	Drug exporters of the RND superfamily
CE197_RS26310	COG3590	peptidase
CE197_RS26315	COG0243	molybdopterin cofactor binding
CE197_RS26330	COG2814	Major facilitator Superfamily
CE197_RS26335	COG1937	Protein conserved in bacteria
CE197_RS26340	COG0129	dihydroxy-acid dehydratase activity
CE197_RS26355	COG4122	O-methyltransferase activity
CE197_RS26365	COG1472	Belongs to the glycosyl hydrolase 3 family
CE197_RS26380	COG2267	carboxylic ester hydrolase activity
CE197_RS26420	COG3619	membrane
CE197_RS26435	COG1714	RDD family
CE197_RS26450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CE197_RS26475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS26480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CE197_RS26490	COG1802	Transcriptional regulator
CE197_RS26510	COG0657	acetylesterase activity
CE197_RS26535	COG1063	alcohol dehydrogenase
CE197_RS26540	COG2124	cytochrome p450
CE197_RS26570	COG1960	acyl-CoA dehydrogenase activity
CE197_RS26575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS26605	COG0277	FAD linked oxidase domain protein
CE197_RS26625	COG1309	transcriptional regulator
CE197_RS26655	COG1960	acyl-CoA dehydrogenase activity
CE197_RS26660	COG2365	Tyrosine phosphatase family
CE197_RS26665	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS26670	COG1012	belongs to the aldehyde dehydrogenase family
CE197_RS26695	COG1741	Belongs to the pirin family
CE197_RS26700	COG0783	Belongs to the Dps family
CE197_RS26720	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CE197_RS26735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CE197_RS26750	COG3585	molybdate ion transport
CE197_RS26755	COG0596	Alpha beta hydrolase
CE197_RS26775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS26810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CE197_RS26850	COG1937	Protein conserved in bacteria
CE197_RS26875	COG1129	ABC transporter
CE197_RS26875	COG0842	Transport permease protein
CE197_RS26895	COG3281	Trehalose synthase
CE197_RS26905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CE197_RS26925	COG0028	Belongs to the TPP enzyme family
CE197_RS26930	COG0583	DNA-binding transcription factor activity
CE197_RS26935	COG1376	ErfK ybiS ycfS ynhG family protein
CE197_RS26965	COG2755	lipolytic protein G-D-S-L family
CE197_RS26965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CE197_RS26975	COG0028	Belongs to the TPP enzyme family
CE197_RS26980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS26990	COG2072	flavoprotein involved in K transport
CE197_RS27000	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS27005	COG3386	PFAM SMP-30 Gluconolaconase
CE197_RS27015	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS27025	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS27085	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CE197_RS27105	COG2226	methyltransferase
CE197_RS27115	COG0300	oxidoreductase activity
CE197_RS27155	COG1063	alcohol dehydrogenase
CE197_RS27175	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS27180	COG2072	flavoprotein involved in K transport
CE197_RS27205	COG0583	DNA-binding transcription factor activity
CE197_RS27225	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS27230	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS27245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CE197_RS27265	COG1309	transcriptional regulator
CE197_RS27275	COG1028	Short-chain dehydrogenase reductase Sdr
CE197_RS27280	COG0318	PFAM AMP-dependent synthetase and ligase
CE197_RS27305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CE197_RS27330	COG1960	acyl-CoA dehydrogenase activity
CE197_RS27335	COG1309	transcriptional regulator
CE197_RS27360	COG3588	fructose-bisphosphate aldolase
CE197_RS27395	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CE197_RS27400	COG4638	Rieske (2fe-2S)
CE197_RS27410	COG2197	response regulator
CE197_RS27415	COG4585	Histidine kinase
CE197_RS27430	COG1674	ftsk spoiiie
CE197_RS27515	COG1595	DNA-templated transcription, initiation
CE197_RS27535	COG0860	N-Acetylmuramoyl-L-alanine amidase
CE197_RS27535	COG3409	Peptidoglycan-binding domain 1 protein
CE197_RS27550	COG1192	Involved in chromosome partitioning
CE197_RS27555	COG0357	Ribosomal RNA small subunit methyltransferase G
CE197_RS27565	COG0706	membrane insertase activity
CE197_RS27570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CE197_RS27685	COG2337	Toxic component of a toxin-antitoxin (TA) module
CE197_RS27695	COG2072	flavoprotein involved in K transport
CE197_RS27730	COG0542	response to heat
CE197_RS27770	COG1376	ErfK ybiS ycfS ynhG family protein
CE197_RS27780	COG1611	Belongs to the LOG family
CE197_RS27900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group