locus-tag	class	description
G6N24_RS00050	COG4638	Rieske (2fe-2S)
G6N24_RS00090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS00100	COG2124	cytochrome p450
G6N24_RS00105	COG1024	Enoyl-CoA hydratase
G6N24_RS00115	COG3001	Fructosamine kinase
G6N24_RS00125	COG0028	Belongs to the TPP enzyme family
G6N24_RS00130	COG0657	acetylesterase activity
G6N24_RS00135	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS00140	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS00145	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS00155	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS00160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS00165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS00190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N24_RS00225	COG1695	Transcriptional regulator
G6N24_RS00230	COG2259	Doxx family
G6N24_RS00235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N24_RS00240	COG0390	transport system, permease component
G6N24_RS00245	COG1024	Enoyl-CoA hydratase
G6N24_RS00255	COG2084	Dehydrogenase
G6N24_RS00265	COG1316	TRANSCRIPTIONal
G6N24_RS00280	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N24_RS00285	COG0477	Major facilitator Superfamily
G6N24_RS00295	COG0028	Belongs to the TPP enzyme family
G6N24_RS00300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N24_RS00305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N24_RS00320	COG0406	alpha-ribazole phosphatase activity
G6N24_RS00365	COG0745	RESPONSE REGULATOR receiver
G6N24_RS00370	COG5000	phosphorelay sensor kinase activity
G6N24_RS00370	COG5002	protein histidine kinase activity
G6N24_RS00400	COG4584	PFAM Integrase catalytic
G6N24_RS00405	COG1484	DNA-dependent DNA replication
G6N24_RS00445	COG4221	oxidoreductase activity
G6N24_RS00460	COG1012	belongs to the aldehyde dehydrogenase family
G6N24_RS00510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N24_RS00525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6N24_RS00545	COG0477	Major facilitator Superfamily
G6N24_RS00560	COG1234	tRNA 3'-trailer cleavage
G6N24_RS00565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N24_RS00585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS00590	COG2188	Transcriptional regulator
G6N24_RS00595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6N24_RS00600	COG0583	DNA-binding transcription factor activity
G6N24_RS00610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G6N24_RS00615	COG1454	alcohol dehydrogenase
G6N24_RS00635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6N24_RS00650	COG2837	iron assimilation
G6N24_RS00655	COG1362	aminopeptidase activity
G6N24_RS00705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N24_RS00730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G6N24_RS00755	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N24_RS00780	COG0745	RESPONSE REGULATOR receiver
G6N24_RS00800	COG0581	inorganic phosphate transmembrane transporter activity
G6N24_RS00805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N24_RS00840	COG0640	Transcriptional regulator
G6N24_RS00845	COG0590	tRNA wobble adenosine to inosine editing
G6N24_RS00905	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N24_RS00925	COG0640	Transcriptional regulator
G6N24_RS00930	COG0798	PFAM Bile acid sodium symporter
G6N24_RS00945	COG1309	transcriptional regulator
G6N24_RS00970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N24_RS00970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N24_RS00975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N24_RS00980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS00985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS00995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N24_RS01005	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS01010	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS01050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N24_RS01055	COG1082	Xylose isomerase domain protein TIM barrel
G6N24_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS01070	COG0277	FAD linked oxidase domain protein
G6N24_RS01075	COG2814	Major facilitator Superfamily
G6N24_RS01080	COG1063	alcohol dehydrogenase
G6N24_RS01090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6N24_RS01095	COG4585	Histidine kinase
G6N24_RS01100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N24_RS01105	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N24_RS01105	COG0022	dehydrogenase e1 component
G6N24_RS01150	COG4585	Histidine kinase
G6N24_RS01155	COG1053	succinate dehydrogenase
G6N24_RS01170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N24_RS01175	COG3384	dioxygenase
G6N24_RS01180	COG1053	succinate dehydrogenase
G6N24_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS01215	COG2132	Multicopper oxidase
G6N24_RS01225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N24_RS01235	COG0019	diaminopimelate decarboxylase activity
G6N24_RS01280	COG0006	proline dipeptidase activity
G6N24_RS01290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS01345	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS01360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N24_RS01370	COG4638	Rieske (2fe-2S)
G6N24_RS01390	COG0183	Belongs to the thiolase family
G6N24_RS01395	COG1309	transcriptional regulator
G6N24_RS01435	COG2124	cytochrome p450
G6N24_RS01465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N24_RS01510	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS01545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS01550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS01555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS01580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N24_RS01620	COG1309	transcriptional regulator
G6N24_RS01630	COG1024	Enoyl-CoA hydratase
G6N24_RS01680	COG0183	Belongs to the thiolase family
G6N24_RS01685	COG1024	Enoyl-CoA hydratase
G6N24_RS01685	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N24_RS01695	COG1309	transcriptional regulator
G6N24_RS01700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS01715	COG0183	Belongs to the thiolase family
G6N24_RS01720	COG1061	Type III restriction enzyme res subunit
G6N24_RS01740	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N24_RS01770	COG1278	Cold shock
G6N24_RS01780	COG5651	PPE family
G6N24_RS01800	COG2814	Major facilitator Superfamily
G6N24_RS01820	COG1846	Transcriptional regulator
G6N24_RS01835	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N24_RS01840	COG3609	addiction module antidote protein, CC2985 family
G6N24_RS01850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N24_RS01875	COG0259	pyridoxamine-phosphate oxidase activity
G6N24_RS01885	COG3328	transposase activity
G6N24_RS01935	COG0438	transferase activity, transferring glycosyl groups
G6N24_RS02015	COG3391	amine dehydrogenase activity
G6N24_RS02045	COG1487	ribonuclease activity
G6N24_RS02060	COG1487	ribonuclease activity
G6N24_RS02075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS02160	COG1316	TRANSCRIPTIONal
G6N24_RS02175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N24_RS02215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N24_RS02225	COG1482	cell wall glycoprotein biosynthetic process
G6N24_RS02230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N24_RS02235	COG0531	amino acid
G6N24_RS02240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N24_RS02280	COG5401	PFAM Sporulation and spore germination
G6N24_RS02295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N24_RS02300	COG0653	protein targeting
G6N24_RS02310	COG2020	methyltransferase activity
G6N24_RS02330	COG2326	polyphosphate kinase activity
G6N24_RS02350	COG1162	GTPase activity
G6N24_RS02355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N24_RS02360	COG2135	peptidase activity
G6N24_RS02380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N24_RS02415	COG0406	alpha-ribazole phosphatase activity
G6N24_RS02430	COG0513	Belongs to the DEAD box helicase family
G6N24_RS02475	COG0596	Alpha beta hydrolase
G6N24_RS02555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N24_RS02575	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N24_RS02630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS02640	COG0163	prenyltransferase activity
G6N24_RS02645	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G6N24_RS02735	COG0596	Alpha beta hydrolase
G6N24_RS02775	COG0714	Associated with various cellular activities
G6N24_RS02810	COG0713	ATP synthesis coupled electron transport
G6N24_RS02885	COG1733	regulation of RNA biosynthetic process
G6N24_RS02890	COG0657	acetylesterase activity
G6N24_RS02900	COG5651	PPE family
G6N24_RS02915	COG2353	YceI-like domain
G6N24_RS02940	COG0604	alcohol dehydrogenase
G6N24_RS02990	COG2124	cytochrome p450
G6N24_RS03000	COG1414	Transcriptional regulator
G6N24_RS03000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G6N24_RS03100	COG0183	Belongs to the thiolase family
G6N24_RS03105	COG2755	lipolytic protein G-D-S-L family
G6N24_RS03110	COG0657	acetylesterase activity
G6N24_RS03150	COG1331	Highly conserved protein containing a thioredoxin domain
G6N24_RS03190	COG0572	uridine kinase
G6N24_RS03200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N24_RS03215	COG0583	DNA-binding transcription factor activity
G6N24_RS03220	COG5263	repeat protein
G6N24_RS03220	COG5651	PPE family
G6N24_RS03225	COG5651	PPE family
G6N24_RS03230	COG0657	acetylesterase activity
G6N24_RS03285	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N24_RS03345	COG5651	PPE family
G6N24_RS03355	COG1722	exodeoxyribonuclease VII activity
G6N24_RS03360	COG1570	exodeoxyribonuclease VII activity
G6N24_RS03390	COG0012	GTP binding
G6N24_RS03450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N24_RS03475	COG0583	DNA-binding transcription factor activity
G6N24_RS03520	COG0574	Belongs to the PEP-utilizing enzyme family
G6N24_RS03520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N24_RS03530	COG1403	HNH endonuclease
G6N24_RS03535	COG3391	amine dehydrogenase activity
G6N24_RS03540	COG1231	oxidoreductase activity
G6N24_RS03545	COG1396	sequence-specific DNA binding
G6N24_RS03545	COG3800	Transcriptional regulator
G6N24_RS03550	COG2079	MmgE PrpD family protein
G6N24_RS03555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G6N24_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS03605	COG1012	belongs to the aldehyde dehydrogenase family
G6N24_RS03610	COG2124	cytochrome p450
G6N24_RS03625	COG3391	amine dehydrogenase activity
G6N24_RS03630	COG3795	YCII-related domain
G6N24_RS03635	COG4941	Belongs to the sigma-70 factor family
G6N24_RS03655	COG0183	Belongs to the thiolase family
G6N24_RS03660	COG1024	Enoyl-CoA hydratase
G6N24_RS03680	COG0657	acetylesterase activity
G6N24_RS03685	COG0702	epimerase
G6N24_RS03695	COG1024	Enoyl-CoA hydratase
G6N24_RS03700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS03710	COG2409	Drug exporters of the RND superfamily
G6N24_RS03745	COG3467	pyridoxamine 5'-phosphate
G6N24_RS03795	COG1140	nitrate reductase beta subunit
G6N24_RS03855	COG1902	pentaerythritol trinitrate reductase activity
G6N24_RS03855	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N24_RS03860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N24_RS03890	COG1140	nitrate reductase beta subunit
G6N24_RS03905	COG2223	nitrite transmembrane transporter activity
G6N24_RS03960	COG0789	Transcriptional regulator
G6N24_RS03990	COG4424	Sulfotransferase
G6N24_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
G6N24_RS04020	COG0506	proline dehydrogenase activity
G6N24_RS04030	COG1309	transcriptional regulator
G6N24_RS04035	COG2124	cytochrome p450
G6N24_RS04050	COG2267	carboxylic ester hydrolase activity
G6N24_RS04055	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS04065	COG0657	acetylesterase activity
G6N24_RS04070	COG5651	PPE family
G6N24_RS04080	COG0477	Major facilitator Superfamily
G6N24_RS04105	COG1611	Belongs to the LOG family
G6N24_RS04120	COG0463	Glycosyl transferase, family 2
G6N24_RS04130	COG0519	Catalyzes the synthesis of GMP from XMP
G6N24_RS04155	COG3559	Exporter of polyketide antibiotics
G6N24_RS04160	COG1131	(ABC) transporter
G6N24_RS04165	COG1309	transcriptional regulator
G6N24_RS04190	COG5662	AntiSigma factor
G6N24_RS04195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N24_RS04200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N24_RS04220	COG2239	Acts as a magnesium transporter
G6N24_RS04260	COG0598	Magnesium transport protein CorA
G6N24_RS04305	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N24_RS04305	COG0567	Dehydrogenase, E1 component
G6N24_RS04360	COG0277	FAD linked oxidase domain protein
G6N24_RS04415	COG0842	Transport permease protein
G6N24_RS04415	COG1716	ATPase activity
G6N24_RS04415	COG1131	(ABC) transporter
G6N24_RS04480	COG1484	DNA-dependent DNA replication
G6N24_RS04490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G6N24_RS04650	COG0477	Major facilitator Superfamily
G6N24_RS04655	COG1733	regulation of RNA biosynthetic process
G6N24_RS04670	COG3391	amine dehydrogenase activity
G6N24_RS04675	COG3391	amine dehydrogenase activity
G6N24_RS04700	COG0018	arginyl-trna synthetase
G6N24_RS04705	COG0019	diaminopimelate decarboxylase activity
G6N24_RS04735	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS04750	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N24_RS04795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6N24_RS04860	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N24_RS04890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N24_RS04900	COG0058	SHG alpha-glucan phosphorylase activity
G6N24_RS04910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N24_RS04950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6N24_RS04960	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N24_RS04965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G6N24_RS04980	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N24_RS04995	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS05015	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05020	COG1802	Transcriptional regulator
G6N24_RS05035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N24_RS05040	COG1024	Enoyl-CoA hydratase
G6N24_RS05065	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N24_RS05110	COG2124	cytochrome p450
G6N24_RS05125	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05130	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05160	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05165	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05170	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05175	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS05230	COG3757	hydrolase, family 25
G6N24_RS05240	COG0736	holo-[acyl-carrier-protein] synthase activity
G6N24_RS05245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N24_RS05265	COG1376	ErfK ybiS ycfS ynhG family protein
G6N24_RS05280	COG0433	COG0433 Predicted ATPase
G6N24_RS05285	COG0300	oxidoreductase activity
G6N24_RS05300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS05320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N24_RS05330	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS05335	COG2030	dehydratase
G6N24_RS05355	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N24_RS05405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N24_RS05495	COG0438	transferase activity, transferring glycosyl groups
G6N24_RS05515	COG1946	Acyl-CoA thioesterase
G6N24_RS05580	COG3391	amine dehydrogenase activity
G6N24_RS05630	COG0632	four-way junction helicase activity
G6N24_RS05650	COG1022	Amp-dependent synthetase and ligase
G6N24_RS05650	COG3320	Male sterility
G6N24_RS05690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6N24_RS05710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N24_RS05725	COG0124	histidyl-tRNA synthetase
G6N24_RS05730	COG1403	HNH endonuclease
G6N24_RS05810	COG5473	translation initiation factor activity
G6N24_RS05835	COG0432	Pfam Uncharacterised protein family UPF0047
G6N24_RS05840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6N24_RS05855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N24_RS05995	COG1982	Orn Lys Arg decarboxylase major
G6N24_RS06025	COG1715	Restriction endonuclease
G6N24_RS06045	COG0657	acetylesterase activity
G6N24_RS06125	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N24_RS06135	COG0194	GDP metabolic process
G6N24_RS06150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N24_RS06160	COG2072	flavoprotein involved in K transport
G6N24_RS06290	COG0322	excinuclease ABC activity
G6N24_RS06300	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6N24_RS06325	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N24_RS06330	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS06340	COG5651	PPE family
G6N24_RS06340	COG3391	amine dehydrogenase activity
G6N24_RS06355	COG1376	ErfK ybiS ycfS ynhG family protein
G6N24_RS06375	COG0126	phosphoglycerate kinase activity
G6N24_RS06380	COG0149	triose-phosphate isomerase activity
G6N24_RS06395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G6N24_RS06435	COG0109	protoheme IX farnesyltransferase activity
G6N24_RS06485	COG1372	Participates in initiation and elongation during chromosome replication
G6N24_RS06485	COG0719	Fe-S assembly protein
G6N24_RS06495	COG0396	ATPase activity
G6N24_RS06505	COG0822	iron-sulfur transferase activity
G6N24_RS06510	COG2151	metal-sulfur cluster biosynthetic enzyme
G6N24_RS06515	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS06525	COG3391	amine dehydrogenase activity
G6N24_RS06540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N24_RS06550	COG0488	(ABC) transporter
G6N24_RS06560	COG1309	transcriptional regulator
G6N24_RS06565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N24_RS06575	COG0791	NLP P60 protein
G6N24_RS06575	COG3883	PFAM NLP P60 protein
G6N24_RS06585	COG0714	Associated with various cellular activities
G6N24_RS06595	COG2304	oxidoreductase activity
G6N24_RS06645	COG0745	RESPONSE REGULATOR receiver
G6N24_RS06690	COG3360	Dodecin
G6N24_RS06695	COG3391	amine dehydrogenase activity
G6N24_RS06695	COG5651	PPE family
G6N24_RS06820	COG4974	Belongs to the 'phage' integrase family
G6N24_RS06845	COG0604	alcohol dehydrogenase
G6N24_RS06845	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS06845	COG3321	synthase
G6N24_RS06855	COG0604	alcohol dehydrogenase
G6N24_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS06855	COG3321	synthase
G6N24_RS06880	COG2070	2-Nitropropane dioxygenase
G6N24_RS06885	COG1309	transcriptional regulator
G6N24_RS06915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6N24_RS06925	COG0252	asparaginase activity
G6N24_RS06960	COG0300	oxidoreductase activity
G6N24_RS07025	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G6N24_RS07075	COG3883	PFAM NLP P60 protein
G6N24_RS07075	COG0791	NLP P60 protein
G6N24_RS07145	COG0157	Belongs to the NadC ModD family
G6N24_RS07175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N24_RS07180	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N24_RS07190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N24_RS07195	COG0107	imidazoleglycerol-phosphate synthase activity
G6N24_RS07275	COG1946	Acyl-CoA thioesterase
G6N24_RS07285	COG1132	(ABC) transporter
G6N24_RS07290	COG4988	ABC transporter
G6N24_RS07295	COG1294	oxidase, subunit
G6N24_RS07300	COG1271	oxidase subunit
G6N24_RS07410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N24_RS07420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G6N24_RS07420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6N24_RS07435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N24_RS07440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N24_RS07495	COG3979	chitinase
G6N24_RS07515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N24_RS07535	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS07545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N24_RS07545	COG0072	phenylalanine-tRNA ligase activity
G6N24_RS07595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N24_RS07610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N24_RS07650	COG3321	synthase
G6N24_RS07650	COG0604	alcohol dehydrogenase
G6N24_RS07650	COG0604	alcohol dehydrogenase
G6N24_RS07650	COG3321	synthase
G6N24_RS07665	COG0488	(ABC) transporter
G6N24_RS07690	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N24_RS07705	COG1131	(ABC) transporter
G6N24_RS07740	COG0647	UMP catabolic process
G6N24_RS07805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N24_RS07810	COG4122	O-methyltransferase activity
G6N24_RS07820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6N24_RS07865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N24_RS07880	COG1160	GTP binding
G6N24_RS07890	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6N24_RS07900	COG3246	L-lysine catabolic process to acetate
G6N24_RS07940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS07965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N24_RS08010	COG1872	DUF167
G6N24_RS08020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N24_RS08060	COG0697	spore germination
G6N24_RS08080	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G6N24_RS08080	COG3261	NADH dehydrogenase
G6N24_RS08085	COG0651	ATP synthesis coupled electron transport
G6N24_RS08095	COG0650	Formate hydrogenlyase subunit 4
G6N24_RS08105	COG3260	NADH ubiquinone oxidoreductase 20
G6N24_RS08115	COG3263	regulation of cellular component size
G6N24_RS08125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6N24_RS08130	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G6N24_RS08135	COG2080	2 iron, 2 sulfur cluster binding
G6N24_RS08150	COG1716	ATPase activity
G6N24_RS08150	COG0842	Transport permease protein
G6N24_RS08150	COG1131	(ABC) transporter
G6N24_RS08195	COG1403	HNH endonuclease
G6N24_RS08200	COG2217	Heavy metal translocating P-type atpase
G6N24_RS08210	COG0300	oxidoreductase activity
G6N24_RS08255	COG0438	transferase activity, transferring glycosyl groups
G6N24_RS08290	COG2226	methyltransferase
G6N24_RS08300	COG0577	efflux transmembrane transporter activity
G6N24_RS08305	COG1136	(ABC) transporter
G6N24_RS08375	COG1937	Protein conserved in bacteria
G6N24_RS08495	COG5651	PPE family
G6N24_RS08525	COG1404	Belongs to the peptidase S8 family
G6N24_RS08580	COG1285	pathogenesis
G6N24_RS08610	COG3573	Dehydrogenase
G6N24_RS08680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N24_RS08680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6N24_RS08705	COG1253	flavin adenine dinucleotide binding
G6N24_RS08710	COG1253	flavin adenine dinucleotide binding
G6N24_RS08720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N24_RS08740	COG0831	urea catabolic process
G6N24_RS08745	COG0832	Belongs to the urease beta subunit family
G6N24_RS08755	COG0830	nickel cation binding
G6N24_RS08770	COG1252	NADH dehydrogenase
G6N24_RS08775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS08835	COG4221	oxidoreductase activity
G6N24_RS08845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS08850	COG0183	Belongs to the thiolase family
G6N24_RS08895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N24_RS08960	COG0174	glutamine synthetase
G6N24_RS08985	COG0300	oxidoreductase activity
G6N24_RS08995	COG1652	LysM domain
G6N24_RS09020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N24_RS09055	COG2070	2-Nitropropane dioxygenase
G6N24_RS09080	COG1490	D-aminoacyl-tRNA deacylase activity
G6N24_RS09100	COG0596	Alpha beta hydrolase
G6N24_RS09105	COG1546	Belongs to the CinA family
G6N24_RS09105	COG1058	Belongs to the CinA family
G6N24_RS09110	COG2814	Major facilitator Superfamily
G6N24_RS09120	COG1950	PFAM Membrane protein of
G6N24_RS09200	COG3336	cytochrome c oxidase
G6N24_RS09220	COG0450	alkyl hydroperoxide reductase
G6N24_RS09225	COG1104	cysteine desulfurase activity
G6N24_RS09235	COG1136	(ABC) transporter
G6N24_RS09245	COG5651	PPE family
G6N24_RS09245	COG5651	PPE family
G6N24_RS09245	COG5263	repeat protein
G6N24_RS09245	COG5651	PPE family
G6N24_RS09245	COG5263	repeat protein
G6N24_RS09245	COG5651	PPE family
G6N24_RS09245	COG5263	repeat protein
G6N24_RS09245	COG5263	repeat protein
G6N24_RS09270	COG2755	lipolytic protein G-D-S-L family
G6N24_RS09270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N24_RS09285	COG2031	fatty acid transporter
G6N24_RS09320	COG4977	sequence-specific DNA binding
G6N24_RS09330	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS09335	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS09340	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS09345	COG1024	Enoyl-CoA hydratase
G6N24_RS09355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6N24_RS09355	COG0543	2 iron, 2 sulfur cluster binding
G6N24_RS09360	COG0596	Alpha beta hydrolase
G6N24_RS09370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N24_RS09370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6N24_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS09390	COG1309	transcriptional regulator
G6N24_RS09405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS09430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N24_RS09475	COG0657	acetylesterase activity
G6N24_RS09480	COG0596	Alpha beta hydrolase
G6N24_RS09495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6N24_RS09515	COG4585	Histidine kinase
G6N24_RS09520	COG0596	Alpha beta hydrolase
G6N24_RS09525	COG1309	transcriptional regulator
G6N24_RS09530	COG2130	NADP-dependent
G6N24_RS09560	COG0657	acetylesterase activity
G6N24_RS09580	COG3757	hydrolase, family 25
G6N24_RS09625	COG1819	glycosyl
G6N24_RS09655	COG1487	ribonuclease activity
G6N24_RS09665	COG1487	ribonuclease activity
G6N24_RS09685	COG1487	ribonuclease activity
G6N24_RS09710	COG3744	PilT protein domain protein
G6N24_RS09760	COG1403	HNH endonuclease
G6N24_RS09795	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G6N24_RS09815	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N24_RS09820	COG3842	ATPase activity
G6N24_RS09825	COG0395	ABC-type sugar transport system, permease component
G6N24_RS09830	COG1175	transmembrane transport
G6N24_RS09845	COG1335	isochorismatase
G6N24_RS09855	COG3265	gluconokinase activity
G6N24_RS09880	COG3161	chorismate lyase activity
G6N24_RS09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS09950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N24_RS10000	COG2367	Beta-lactamase
G6N24_RS10025	COG0300	oxidoreductase activity
G6N24_RS10080	COG1511	domain protein
G6N24_RS10135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6N24_RS10165	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N24_RS10210	COG1222	aaa ATPase
G6N24_RS10260	COG5651	PPE family
G6N24_RS10330	COG1410	methionine synthase
G6N24_RS10330	COG0646	methionine synthase
G6N24_RS10345	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS10405	COG0167	dihydroorotate dehydrogenase activity
G6N24_RS10425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N24_RS10475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6N24_RS10490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N24_RS10515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6N24_RS10520	COG0789	Transcriptional regulator
G6N24_RS10530	COG0484	heat shock protein binding
G6N24_RS10540	COG3328	transposase activity
G6N24_RS10555	COG0768	penicillin binding
G6N24_RS10580	COG0454	-acetyltransferase
G6N24_RS10580	COG0456	acetyltransferase
G6N24_RS10615	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N24_RS10650	COG0003	Pfam Anion-transporting ATPase
G6N24_RS10665	COG1022	Amp-dependent synthetase and ligase
G6N24_RS10745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N24_RS10775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6N24_RS10800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6N24_RS10825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6N24_RS11025	COG0277	FAD linked oxidase domain protein
G6N24_RS11050	COG2226	methyltransferase
G6N24_RS11070	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G6N24_RS11075	COG4221	oxidoreductase activity
G6N24_RS11210	COG1309	transcriptional regulator
G6N24_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS11380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N24_RS11410	COG1403	HNH endonuclease
G6N24_RS11460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N24_RS11465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N24_RS11470	COG0022	dehydrogenase e1 component
G6N24_RS11475	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N24_RS11525	COG0569	domain protein
G6N24_RS11525	COG0475	glutathione-regulated potassium exporter activity
G6N24_RS11530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS11585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N24_RS11605	COG1175	transmembrane transport
G6N24_RS11610	COG0395	ABC-type sugar transport system, permease component
G6N24_RS11625	COG0531	amino acid
G6N24_RS11630	COG1834	amidinotransferase
G6N24_RS11680	COG2223	nitrite transmembrane transporter activity
G6N24_RS11705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N24_RS11710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N24_RS11725	COG1045	serine acetyltransferase
G6N24_RS11855	COG1381	Involved in DNA repair and RecF pathway recombination
G6N24_RS11865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6N24_RS11880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6N24_RS11905	COG1420	regulation of RNA biosynthetic process
G6N24_RS11920	COG1595	DNA-templated transcription, initiation
G6N24_RS11955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS11955	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N24_RS11965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS12000	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N24_RS12065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N24_RS12090	COG4208	sulfate ABC transporter
G6N24_RS12095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6N24_RS12100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N24_RS12115	COG3387	PFAM Glycoside hydrolase 15-related
G6N24_RS12135	COG0517	IMP dehydrogenase activity
G6N24_RS12140	COG1234	tRNA 3'-trailer cleavage
G6N24_RS12150	COG1305	Transglutaminase-like
G6N24_RS12160	COG2308	Evidence 4 Homologs of previously reported genes of
G6N24_RS12165	COG0268	Binds directly to 16S ribosomal RNA
G6N24_RS12180	COG1596	polysaccharide export
G6N24_RS12180	COG1555	photosystem II stabilization
G6N24_RS12190	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS12215	COG0657	acetylesterase activity
G6N24_RS12225	COG2755	lipolytic protein G-D-S-L family
G6N24_RS12235	COG0799	negative regulation of ribosome biogenesis
G6N24_RS12240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6N24_RS12245	COG2002	toxin-antitoxin pair type II binding
G6N24_RS12265	COG0542	response to heat
G6N24_RS12270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N24_RS12275	COG0668	transmembrane transport
G6N24_RS12285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N24_RS12315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6N24_RS12330	COG1530	ribonuclease E activity
G6N24_RS12335	COG0105	UTP biosynthetic process
G6N24_RS12345	COG0285	dihydrofolate synthase activity
G6N24_RS12360	COG3268	Saccharopine dehydrogenase
G6N24_RS12370	COG1388	LysM domain
G6N24_RS12375	COG0746	molybdenum cofactor guanylyltransferase activity
G6N24_RS12380	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N24_RS12385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N24_RS12385	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N24_RS12390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6N24_RS12395	COG2040	homocysteine
G6N24_RS12400	COG0740	serine-type endopeptidase activity
G6N24_RS12440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N24_RS12470	COG2346	COG2346, Truncated hemoglobins
G6N24_RS12475	COG0366	Alpha amylase catalytic
G6N24_RS12485	COG0824	Thioesterase
G6N24_RS12490	COG2902	Dehydrogenase
G6N24_RS12500	COG0629	single-stranded DNA binding
G6N24_RS12555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N24_RS12560	COG3485	protocatechuate 3,4-dioxygenase
G6N24_RS12565	COG3485	protocatechuate 3,4-dioxygenase
G6N24_RS12580	COG4638	Rieske (2fe-2S)
G6N24_RS12600	COG0235	Class ii aldolase
G6N24_RS12605	COG1414	Transcriptional regulator
G6N24_RS12735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N24_RS12795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N24_RS12800	COG0531	amino acid
G6N24_RS12805	COG0569	domain protein
G6N24_RS12835	COG0756	dUTP diphosphatase activity
G6N24_RS12955	COG1388	LysM domain
G6N24_RS12960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6N24_RS12980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N24_RS12985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6N24_RS13010	COG1196	nuclear chromosome segregation
G6N24_RS13030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6N24_RS13030	COG1372	Participates in initiation and elongation during chromosome replication
G6N24_RS13050	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N24_RS13080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N24_RS13125	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G6N24_RS13135	COG3214	Protein conserved in bacteria
G6N24_RS13155	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS13160	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS13165	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS13200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N24_RS13225	COG1522	sequence-specific DNA binding
G6N24_RS13230	COG0686	Belongs to the AlaDH PNT family
G6N24_RS13265	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS13270	COG0183	Belongs to the thiolase family
G6N24_RS13335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6N24_RS13355	COG4118	positive regulation of growth
G6N24_RS13370	COG0657	acetylesterase activity
G6N24_RS13395	COG3744	PilT protein domain protein
G6N24_RS13420	COG3391	amine dehydrogenase activity
G6N24_RS13425	COG3842	ATPase activity
G6N24_RS13430	COG1653	transport
G6N24_RS13435	COG0395	ABC-type sugar transport system, permease component
G6N24_RS13445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N24_RS13450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6N24_RS13505	COG1648	precorrin-2 dehydrogenase activity
G6N24_RS13505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N24_RS13515	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G6N24_RS13555	COG0735	belongs to the Fur family
G6N24_RS13560	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N24_RS13565	COG0375	protein maturation
G6N24_RS13590	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G6N24_RS13600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G6N24_RS13605	COG0309	Hydrogenase expression formation protein (HypE)
G6N24_RS13645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N24_RS13660	COG1492	cobalamin metabolic process
G6N24_RS13740	COG0233	cytoplasmic translational termination
G6N24_RS13750	COG0745	RESPONSE REGULATOR receiver
G6N24_RS13765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6N24_RS13770	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N24_RS13835	COG0335	large ribosomal subunit rRNA binding
G6N24_RS13855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N24_RS13865	COG0228	four-way junction DNA binding
G6N24_RS13875	COG1686	Belongs to the peptidase S11 family
G6N24_RS13925	COG1403	HNH endonuclease
G6N24_RS13940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N24_RS13985	COG3599	regulation of cell shape
G6N24_RS13990	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6N24_RS14000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS14000	COG3321	synthase
G6N24_RS14010	COG3321	synthase
G6N24_RS14010	COG0604	alcohol dehydrogenase
G6N24_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS14060	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS14100	COG3161	chorismate lyase activity
G6N24_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS14165	COG0742	ribosomal rna small subunit methyltransferase
G6N24_RS14170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N24_RS14210	COG1461	Dihydroxyacetone kinase
G6N24_RS14250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G6N24_RS14275	COG0066	3-isopropylmalate dehydratase activity
G6N24_RS14280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N24_RS14305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N24_RS14310	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N24_RS14315	COG2271	Major facilitator Superfamily
G6N24_RS14320	COG0473	3-isopropylmalate dehydrogenase activity
G6N24_RS14335	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6N24_RS14390	COG0205	6-phosphofructokinase activity
G6N24_RS14395	COG0154	amidase activity
G6N24_RS14420	COG0640	Transcriptional regulator
G6N24_RS14480	COG0482	sulfurtransferase activity
G6N24_RS14500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N24_RS14540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N24_RS14565	COG1937	Protein conserved in bacteria
G6N24_RS14575	COG0110	maltose O-acetyltransferase activity
G6N24_RS14580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N24_RS14610	COG1119	ATPase activity
G6N24_RS14615	COG0560	Phosphoserine phosphatase
G6N24_RS14615	COG3830	Belongs to the UPF0237 family
G6N24_RS14665	COG1309	transcriptional regulator
G6N24_RS14735	COG2186	Transcriptional regulator
G6N24_RS14750	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS14765	COG1966	Carbon starvation protein
G6N24_RS14875	COG2354	Protein conserved in bacteria
G6N24_RS14885	COG2130	NADP-dependent
G6N24_RS14900	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS14915	COG0657	acetylesterase activity
G6N24_RS14935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N24_RS14945	COG0657	acetylesterase activity
G6N24_RS15000	COG2177	Part of the ABC transporter FtsEX involved in
G6N24_RS15005	COG2884	Cell division ATP-binding protein ftsE
G6N24_RS15015	COG0668	transmembrane transport
G6N24_RS15020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6N24_RS15030	COG0277	FAD linked oxidase domain protein
G6N24_RS15085	COG0483	inositol monophosphate 1-phosphatase activity
G6N24_RS15100	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS15105	COG3979	chitinase
G6N24_RS15180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N24_RS15225	COG0657	acetylesterase activity
G6N24_RS15245	COG0745	RESPONSE REGULATOR receiver
G6N24_RS15250	COG2205	protein histidine kinase activity
G6N24_RS15265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N24_RS15270	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6N24_RS15315	COG3956	TIGRFAM MazG family protein
G6N24_RS15360	COG1393	Belongs to the ArsC family
G6N24_RS15380	COG0193	aminoacyl-tRNA hydrolase activity
G6N24_RS15390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS15395	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS15415	COG0084	hydrolase, TatD family'
G6N24_RS15475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N24_RS15475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N24_RS15520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N24_RS15525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N24_RS15540	COG1970	mechanosensitive ion channel activity
G6N24_RS15545	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N24_RS15545	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N24_RS15550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N24_RS15555	COG2205	protein histidine kinase activity
G6N24_RS15580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N24_RS15595	COG1024	Enoyl-CoA hydratase
G6N24_RS15690	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N24_RS15715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N24_RS15720	COG0166	Belongs to the GPI family
G6N24_RS15730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N24_RS15765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS15795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS15805	COG0659	secondary active sulfate transmembrane transporter activity
G6N24_RS15830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N24_RS15835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6N24_RS15850	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G6N24_RS15850	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G6N24_RS15855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N24_RS15875	COG1403	HNH endonuclease
G6N24_RS15890	COG4770	biotin carboxylase activity
G6N24_RS15925	COG1522	sequence-specific DNA binding
G6N24_RS15930	COG1012	belongs to the aldehyde dehydrogenase family
G6N24_RS15935	COG1309	transcriptional regulator
G6N24_RS15940	COG1201	RNA secondary structure unwinding
G6N24_RS15970	COG3119	arylsulfatase activity
G6N24_RS15970	COG3408	Glycogen debranching enzyme
G6N24_RS15975	COG0564	pseudouridine synthase activity
G6N24_RS16010	COG1473	amidohydrolase
G6N24_RS16010	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N24_RS16025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N24_RS16035	COG3511	phospholipase C
G6N24_RS16070	COG0657	acetylesterase activity
G6N24_RS16090	COG2009	succinate dehydrogenase
G6N24_RS16100	COG1053	succinate dehydrogenase
G6N24_RS16105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N24_RS16120	COG1595	DNA-templated transcription, initiation
G6N24_RS16125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N24_RS16130	COG1686	Belongs to the peptidase S11 family
G6N24_RS16155	COG2814	Major facilitator Superfamily
G6N24_RS16170	COG1295	ribonuclease BN
G6N24_RS16195	COG2873	o-acetylhomoserine
G6N24_RS16210	COG5651	PPE family
G6N24_RS16210	COG5651	PPE family
G6N24_RS16210	COG5651	PPE family
G6N24_RS16220	COG0277	FAD linked oxidase domain protein
G6N24_RS16240	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N24_RS16240	COG1902	pentaerythritol trinitrate reductase activity
G6N24_RS16245	COG1131	(ABC) transporter
G6N24_RS16245	COG1716	ATPase activity
G6N24_RS16245	COG0842	Transport permease protein
G6N24_RS16250	COG1716	ATPase activity
G6N24_RS16250	COG1131	(ABC) transporter
G6N24_RS16250	COG0842	Transport permease protein
G6N24_RS16270	COG2018	Roadblock/LC7 domain
G6N24_RS16280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N24_RS16300	COG0587	DNA-directed DNA polymerase activity
G6N24_RS16305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N24_RS16330	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N24_RS16335	COG2030	dehydratase
G6N24_RS16340	COG0406	alpha-ribazole phosphatase activity
G6N24_RS16350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS16390	COG1309	transcriptional regulator
G6N24_RS16485	COG0456	acetyltransferase
G6N24_RS16490	COG1214	PFAM Peptidase M22, glycoprotease
G6N24_RS16490	COG0456	acetyltransferase
G6N24_RS16510	COG0076	glutamate decarboxylase activity
G6N24_RS16525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N24_RS16570	COG4842	Belongs to the WXG100 family
G6N24_RS16585	COG4842	Belongs to the WXG100 family
G6N24_RS16595	COG1674	ftsk spoiiie
G6N24_RS16605	COG1404	Belongs to the peptidase S8 family
G6N24_RS16640	COG0202	RNA polymerase activity
G6N24_RS16650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N24_RS16655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6N24_RS16660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N24_RS16665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N24_RS16685	COG1403	HNH endonuclease
G6N24_RS16695	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS16710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N24_RS16725	COG0028	Belongs to the TPP enzyme family
G6N24_RS16755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS16780	COG1917	Cupin 2, conserved barrel domain protein
G6N24_RS16780	COG2207	Transcriptional regulator
G6N24_RS16785	COG2226	methyltransferase
G6N24_RS16795	COG0300	oxidoreductase activity
G6N24_RS16815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS16820	COG0616	signal peptide processing
G6N24_RS16825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS16910	COG4942	peptidase
G6N24_RS16920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N24_RS16945	COG1484	DNA-dependent DNA replication
G6N24_RS16960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N24_RS16970	COG0255	Belongs to the universal ribosomal protein uL29 family
G6N24_RS16985	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6N24_RS16990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N24_RS16995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6N24_RS17000	COG0089	rRNA binding
G6N24_RS17010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6N24_RS17030	COG1484	DNA-dependent DNA replication
G6N24_RS17050	COG1657	PFAM Prenyltransferase squalene oxidase
G6N24_RS17060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6N24_RS17105	COG0535	radical SAM domain protein
G6N24_RS17185	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS17205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N24_RS17230	COG0222	ribosome binding
G6N24_RS17240	COG1940	carbohydrate kinase activity
G6N24_RS17265	COG2267	carboxylic ester hydrolase activity
G6N24_RS17270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS17275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS17280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS17285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS17295	COG4941	Belongs to the sigma-70 factor family
G6N24_RS17300	COG0081	regulation of translation
G6N24_RS17315	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N24_RS17330	COG2030	dehydratase
G6N24_RS17335	COG2030	dehydratase
G6N24_RS17340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6N24_RS17360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N24_RS17375	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N24_RS17385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N24_RS17400	COG0346	lactoylglutathione lyase activity
G6N24_RS17460	COG3537	Alpha-1,2-mannosidase
G6N24_RS17480	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N24_RS17575	COG0501	Belongs to the peptidase M48B family
G6N24_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS17655	COG4221	oxidoreductase activity
G6N24_RS17665	COG0306	phosphate transporter
G6N24_RS17710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6N24_RS17715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N24_RS17745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N24_RS17755	COG0785	Cytochrome C biogenesis protein
G6N24_RS17765	COG0406	alpha-ribazole phosphatase activity
G6N24_RS17775	COG1403	HNH endonuclease
G6N24_RS17780	COG0535	radical SAM domain protein
G6N24_RS17785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G6N24_RS17790	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS17800	COG1113	amino acid transport
G6N24_RS17825	COG2755	lipolytic protein G-D-S-L family
G6N24_RS17860	COG1587	Uroporphyrinogen-III synthase
G6N24_RS17860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N24_RS17865	COG0181	hydroxymethylbilane synthase activity
G6N24_RS17880	COG0560	Phosphoserine phosphatase
G6N24_RS17890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS18010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G6N24_RS18055	COG2733	membrane
G6N24_RS18130	COG1505	serine-type exopeptidase activity
G6N24_RS18140	COG1024	Enoyl-CoA hydratase
G6N24_RS18210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS18220	COG1595	DNA-templated transcription, initiation
G6N24_RS18240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N24_RS18285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N24_RS18295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N24_RS18315	COG0242	peptide deformylase activity
G6N24_RS18390	COG2234	aminopeptidase activity
G6N24_RS18395	COG2234	aminopeptidase activity
G6N24_RS18450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N24_RS18480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N24_RS18490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS18495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS18500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS18515	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS18520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N24_RS18530	COG1403	HNH endonuclease
G6N24_RS18535	COG1252	NADH dehydrogenase
G6N24_RS18565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6N24_RS18575	COG1994	Peptidase M50
G6N24_RS18625	COG0746	molybdenum cofactor guanylyltransferase activity
G6N24_RS18660	COG3360	Dodecin
G6N24_RS18725	COG1403	HNH endonuclease
G6N24_RS18740	COG0789	Transcriptional regulator
G6N24_RS18840	COG0247	lactate metabolic process
G6N24_RS18840	COG2181	nitrate reductase activity
G6N24_RS18850	COG1403	HNH endonuclease
G6N24_RS18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N24_RS18915	COG0717	Belongs to the dCTP deaminase family
G6N24_RS18940	COG2442	InterPro IPR007367
G6N24_RS18975	COG1846	Transcriptional regulator
G6N24_RS18985	COG2130	NADP-dependent
G6N24_RS19035	COG0671	phosphoesterase, PA-phosphatase related
G6N24_RS19045	COG0778	Nitroreductase
G6N24_RS19070	COG1404	Belongs to the peptidase S8 family
G6N24_RS19125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS19130	COG5651	PPE family
G6N24_RS19160	COG0346	lactoylglutathione lyase activity
G6N24_RS19175	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS19245	COG1984	allophanate hydrolase subunit 2
G6N24_RS19280	COG2146	nitrite reductase [NAD(P)H] activity
G6N24_RS19280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N24_RS19300	COG1053	succinate dehydrogenase
G6N24_RS19320	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS19330	COG0183	Belongs to the thiolase family
G6N24_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS19340	COG2030	dehydratase
G6N24_RS19355	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N24_RS19365	COG4981	capsule polysaccharide biosynthetic process
G6N24_RS19445	COG0297	glycogen (starch) synthase activity
G6N24_RS19450	COG0500	methyltransferase
G6N24_RS19480	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS19550	COG1024	Enoyl-CoA hydratase
G6N24_RS19560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G6N24_RS19595	COG2161	toxin-antitoxin pair type II binding
G6N24_RS19605	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G6N24_RS19630	COG2409	Drug exporters of the RND superfamily
G6N24_RS19670	COG3590	peptidase
G6N24_RS19675	COG0243	molybdopterin cofactor binding
G6N24_RS19685	COG2197	response regulator
G6N24_RS19700	COG1376	ErfK ybiS ycfS ynhG family protein
G6N24_RS19705	COG1376	ErfK ybiS ycfS ynhG family protein
G6N24_RS19710	COG2814	Major facilitator Superfamily
G6N24_RS19715	COG1937	Protein conserved in bacteria
G6N24_RS19735	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N24_RS19750	COG2267	carboxylic ester hydrolase activity
G6N24_RS19800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N24_RS19825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS19830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS19890	COG0277	FAD linked oxidase domain protein
G6N24_RS19905	COG0657	acetylesterase activity
G6N24_RS19905	COG5651	PPE family
G6N24_RS19910	COG0657	acetylesterase activity
G6N24_RS19910	COG5651	PPE family
G6N24_RS19915	COG1309	transcriptional regulator
G6N24_RS19960	COG3321	synthase
G6N24_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS19960	COG0604	alcohol dehydrogenase
G6N24_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS19970	COG1012	belongs to the aldehyde dehydrogenase family
G6N24_RS19975	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N24_RS19980	COG1309	transcriptional regulator
G6N24_RS19985	COG0038	chloride channel
G6N24_RS20020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N24_RS20070	COG1309	transcriptional regulator
G6N24_RS20080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS20115	COG3281	Trehalose synthase
G6N24_RS20125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N24_RS20135	COG0657	acetylesterase activity
G6N24_RS20145	COG0657	acetylesterase activity
G6N24_RS20170	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS20175	COG0028	Belongs to the TPP enzyme family
G6N24_RS20180	COG0583	DNA-binding transcription factor activity
G6N24_RS20185	COG1376	ErfK ybiS ycfS ynhG family protein
G6N24_RS20210	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6N24_RS20210	COG0235	Class ii aldolase
G6N24_RS20215	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G6N24_RS20220	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G6N24_RS20250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N24_RS20250	COG2755	lipolytic protein G-D-S-L family
G6N24_RS20255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS20265	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS20270	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS20295	COG1403	HNH endonuclease
G6N24_RS20330	COG4842	Belongs to the WXG100 family
G6N24_RS20450	COG1309	transcriptional regulator
G6N24_RS20455	COG0657	acetylesterase activity
G6N24_RS20460	COG0583	DNA-binding transcription factor activity
G6N24_RS20475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N24_RS20480	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS20555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N24_RS20580	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS20615	COG0277	FAD linked oxidase domain protein
G6N24_RS20630	COG1733	regulation of RNA biosynthetic process
G6N24_RS20665	COG4584	PFAM Integrase catalytic
G6N24_RS20670	COG1484	DNA-dependent DNA replication
G6N24_RS20700	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N24_RS20715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N24_RS20740	COG0596	Alpha beta hydrolase
G6N24_RS20765	COG0495	leucyl-tRNA aminoacylation
G6N24_RS20855	COG1716	ATPase activity
G6N24_RS20880	COG0515	serine threonine protein kinase
G6N24_RS20935	COG1372	Participates in initiation and elongation during chromosome replication
G6N24_RS20935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N24_RS20945	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N24_RS20950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6N24_RS20955	COG0592	DNA-directed DNA polymerase activity
G6N24_RS20960	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N24_RS20970	COG0594	ribonuclease P activity
G6N24_RS20980	COG0706	membrane insertase activity
G6N24_RS20995	COG1192	Involved in chromosome partitioning
G6N24_RS21010	COG3409	Peptidoglycan-binding domain 1 protein
G6N24_RS21010	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N24_RS21155	COG1484	DNA-dependent DNA replication
G6N24_RS21265	COG1674	ftsk spoiiie
G6N24_RS21295	COG5651	PPE family
G6N24_RS21325	COG1404	Belongs to the peptidase S8 family
G6N24_RS21340	COG1404	Belongs to the peptidase S8 family
G6N24_RS21365	COG4932	domain protein
G6N24_RS21465	COG0067	glutamate synthase
G6N24_RS21465	COG0070	glutamate synthase
G6N24_RS21465	COG0069	glutamate synthase activity
G6N24_RS21480	COG1796	DNA polymerase
G6N24_RS21480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N24_RS21530	COG2119	membrane
G6N24_RS21560	COG1316	TRANSCRIPTIONal
G6N24_RS21595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6N24_RS21645	COG0561	phosphatase activity
G6N24_RS21655	COG0754	glutathionylspermidine amidase activity
G6N24_RS21660	COG3766	membrane
G6N24_RS21715	COG1216	Glycosyl transferase, family 2
G6N24_RS21730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N24_RS21755	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS21765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N24_RS21770	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS21800	COG1113	amino acid transport
G6N24_RS21820	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G6N24_RS21900	COG3321	synthase
G6N24_RS21900	COG0604	alcohol dehydrogenase
G6N24_RS21900	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS21975	COG0739	heme binding
G6N24_RS21990	COG0745	RESPONSE REGULATOR receiver
G6N24_RS21995	COG2205	protein histidine kinase activity
G6N24_RS22005	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G6N24_RS22035	COG0406	alpha-ribazole phosphatase activity
G6N24_RS22045	COG5416	Lipopolysaccharide assembly protein A domain
G6N24_RS22055	COG0517	IMP dehydrogenase activity
G6N24_RS22055	COG1125	glycine betaine transport
G6N24_RS22060	COG1174	glycine betaine transport
G6N24_RS22075	COG0287	Prephenate dehydrogenase
G6N24_RS22090	COG0590	tRNA wobble adenosine to inosine editing
G6N24_RS22105	COG4974	Belongs to the 'phage' integrase family
G6N24_RS22115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G6N24_RS22145	COG0393	Putative heavy-metal-binding
G6N24_RS22170	COG2813	Specifically methylates the guanine in position
G6N24_RS22175	COG2072	flavoprotein involved in K transport
G6N24_RS22195	COG1403	HNH endonuclease
G6N24_RS22280	COG1793	dna ligase
G6N24_RS22290	COG3549	Plasmid maintenance system killer
G6N24_RS22300	COG0477	Major facilitator Superfamily
G6N24_RS22305	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G6N24_RS22310	COG1063	alcohol dehydrogenase
G6N24_RS22415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N24_RS22425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N24_RS22440	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N24_RS22465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G6N24_RS22470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6N24_RS22515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N24_RS22530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N24_RS22560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N24_RS22565	COG1695	Transcriptional regulator
G6N24_RS22585	COG0714	Associated with various cellular activities
G6N24_RS22625	COG2172	sigma factor antagonist activity
G6N24_RS22630	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N24_RS22635	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N24_RS22660	COG0583	DNA-binding transcription factor activity
G6N24_RS22670	COG0657	acetylesterase activity
G6N24_RS22680	COG0583	DNA-binding transcription factor activity
G6N24_RS22685	COG2936	dipeptidyl-peptidase activity
G6N24_RS22715	COG0640	Transcriptional regulator
G6N24_RS22725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N24_RS22730	COG1408	metallophosphoesterase
G6N24_RS22765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N24_RS22845	COG0601	transmembrane transport
G6N24_RS22850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N24_RS22855	COG4172	Belongs to the ABC transporter superfamily
G6N24_RS22925	COG1111	helicase
G6N24_RS22925	COG1205	dead DEAH box helicase
G6N24_RS22950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G6N24_RS22985	COG0657	acetylesterase activity
G6N24_RS23020	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N24_RS23055	COG1063	alcohol dehydrogenase
G6N24_RS23065	COG2267	carboxylic ester hydrolase activity
G6N24_RS23070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N24_RS23075	COG0302	gtp cyclohydrolase
G6N24_RS23110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N24_RS23115	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G6N24_RS23175	COG3391	amine dehydrogenase activity
G6N24_RS23215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N24_RS23220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6N24_RS23225	COG0215	cysteine-tRNA ligase activity
G6N24_RS23230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N24_RS23255	COG1609	Transcriptional regulator
G6N24_RS23260	COG1309	transcriptional regulator
G6N24_RS23265	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N24_RS23365	COG0436	Aminotransferase
G6N24_RS23370	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23375	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23380	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23385	COG0318	PFAM AMP-dependent synthetase and ligase
G6N24_RS23390	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23405	COG3654	unkown
G6N24_RS23425	COG0183	Belongs to the thiolase family
G6N24_RS23450	COG1024	Enoyl-CoA hydratase
G6N24_RS23460	COG1028	Short-chain dehydrogenase reductase Sdr
G6N24_RS23475	COG0183	Belongs to the thiolase family
G6N24_RS23485	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23490	COG1960	acyl-CoA dehydrogenase activity
G6N24_RS23495	COG2030	dehydratase
G6N24_RS23525	COG1484	DNA-dependent DNA replication
G6N24_RS23535	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6N24_RS23545	COG2030	dehydratase
G6N24_RS23555	COG3971	2-oxopent-4-enoate hydratase activity
G6N24_RS23570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N24_RS23600	COG4638	Rieske (2fe-2S)
