locus-tag	class	description
MM1218R_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MM1218R_RS00010	COG0592	DNA-directed DNA polymerase activity
MM1218R_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MM1218R_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MM1218R_RS00025	COG0187	DNA topoisomerase II activity
MM1218R_RS00050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MM1218R_RS00055	COG0789	Transcriptional regulator
MM1218R_RS00095	COG0515	serine threonine protein kinase
MM1218R_RS00120	COG1716	ATPase activity
MM1218R_RS00130	COG3415	Transposase
MM1218R_RS00130	COG2801	Transposase and inactivated derivatives
MM1218R_RS00160	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS00165	COG3022	response to hydroperoxide
MM1218R_RS00175	COG1174	glycine betaine transport
MM1218R_RS00180	COG1125	glycine betaine transport
MM1218R_RS00180	COG0517	IMP dehydrogenase activity
MM1218R_RS00185	COG1174	glycine betaine transport
MM1218R_RS00190	COG1278	Cold shock
MM1218R_RS00275	COG1678	Uncharacterized ACR, COG1678
MM1218R_RS00295	COG0495	leucyl-tRNA aminoacylation
MM1218R_RS00300	COG0300	oxidoreductase activity
MM1218R_RS00315	COG0765	amino acid transport
MM1218R_RS00325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS00330	COG0596	Alpha beta hydrolase
MM1218R_RS00330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MM1218R_RS00335	COG1260	myo-inositol-1-phosphate synthase
MM1218R_RS00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM1218R_RS00380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MM1218R_RS00385	COG0359	binds to the 23S rRNA
MM1218R_RS00430	COG0477	Major facilitator Superfamily
MM1218R_RS00450	COG3321	synthase
MM1218R_RS00450	COG0604	alcohol dehydrogenase
MM1218R_RS00460	COG3161	chorismate lyase activity
MM1218R_RS00490	COG2030	dehydratase
MM1218R_RS00510	COG0277	FAD linked oxidase domain protein
MM1218R_RS00550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM1218R_RS00560	COG2124	cytochrome p450
MM1218R_RS00570	COG0604	alcohol dehydrogenase
MM1218R_RS00595	COG0543	2 iron, 2 sulfur cluster binding
MM1218R_RS00595	COG0633	Ferredoxin
MM1218R_RS00610	COG3350	monooxygenase activity
MM1218R_RS00615	COG2197	response regulator
MM1218R_RS00620	COG4585	Histidine kinase
MM1218R_RS00630	COG0494	nUDIX hydrolase
MM1218R_RS00635	COG0477	Major facilitator Superfamily
MM1218R_RS00650	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS00665	COG0183	Belongs to the thiolase family
MM1218R_RS00680	COG1846	Transcriptional regulator
MM1218R_RS00700	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS00705	COG1309	transcriptional regulator
MM1218R_RS00725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS00825	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS00830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS00870	COG0657	acetylesterase activity
MM1218R_RS00920	COG4842	Belongs to the WXG100 family
MM1218R_RS00985	COG0509	glycine decarboxylation via glycine cleavage system
MM1218R_RS00990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MM1218R_RS00995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM1218R_RS00995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM1218R_RS01005	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MM1218R_RS01060	COG1309	transcriptional regulator
MM1218R_RS01085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MM1218R_RS01140	COG2072	flavoprotein involved in K transport
MM1218R_RS01145	COG2072	flavoprotein involved in K transport
MM1218R_RS01170	COG1024	Enoyl-CoA hydratase
MM1218R_RS01210	COG4221	oxidoreductase activity
MM1218R_RS01215	COG1033	growth of symbiont in host cell
MM1218R_RS01215	COG2409	Drug exporters of the RND superfamily
MM1218R_RS01220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS01320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MM1218R_RS01325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM1218R_RS01330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MM1218R_RS01345	COG0254	rRNA binding
MM1218R_RS01355	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS01395	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS01405	COG3386	PFAM SMP-30 Gluconolaconase
MM1218R_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS01425	COG2072	flavoprotein involved in K transport
MM1218R_RS01430	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS01435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS01440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MM1218R_RS01440	COG2755	lipolytic protein G-D-S-L family
MM1218R_RS01460	COG1376	ErfK ybiS ycfS ynhG family protein
MM1218R_RS01465	COG0583	DNA-binding transcription factor activity
MM1218R_RS01470	COG0028	Belongs to the TPP enzyme family
MM1218R_RS01505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM1218R_RS01515	COG3281	Trehalose synthase
MM1218R_RS01550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM1218R_RS01550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MM1218R_RS01555	COG1309	transcriptional regulator
MM1218R_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS01620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM1218R_RS01630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM1218R_RS01650	COG0038	chloride channel
MM1218R_RS01655	COG1741	Belongs to the pirin family
MM1218R_RS01660	COG1309	transcriptional regulator
MM1218R_RS01665	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS01670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS01675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS01690	COG0604	alcohol dehydrogenase
MM1218R_RS01690	COG3321	synthase
MM1218R_RS01705	COG5651	PPE family
MM1218R_RS01715	COG2365	Tyrosine phosphatase family
MM1218R_RS01755	COG1309	transcriptional regulator
MM1218R_RS01760	COG0657	acetylesterase activity
MM1218R_RS01760	COG5651	PPE family
MM1218R_RS01765	COG0657	acetylesterase activity
MM1218R_RS01765	COG5651	PPE family
MM1218R_RS01770	COG0657	acetylesterase activity
MM1218R_RS01770	COG5651	PPE family
MM1218R_RS01790	COG0277	FAD linked oxidase domain protein
MM1218R_RS01830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS01870	COG0657	acetylesterase activity
MM1218R_RS01890	COG1802	Transcriptional regulator
MM1218R_RS01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS01930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MM1218R_RS01945	COG1714	RDD family
MM1218R_RS01985	COG2267	carboxylic ester hydrolase activity
MM1218R_RS02000	COG1472	Belongs to the glycosyl hydrolase 3 family
MM1218R_RS02010	COG0657	acetylesterase activity
MM1218R_RS02020	COG0129	dihydroxy-acid dehydratase activity
MM1218R_RS02025	COG1937	Protein conserved in bacteria
MM1218R_RS02030	COG2814	Major facilitator Superfamily
MM1218R_RS02035	COG1376	ErfK ybiS ycfS ynhG family protein
MM1218R_RS02045	COG0243	molybdopterin cofactor binding
MM1218R_RS02050	COG3590	peptidase
MM1218R_RS02090	COG2409	Drug exporters of the RND superfamily
MM1218R_RS02100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MM1218R_RS02115	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MM1218R_RS02125	COG1024	Enoyl-CoA hydratase
MM1218R_RS02170	COG0657	acetylesterase activity
MM1218R_RS02180	COG1024	Enoyl-CoA hydratase
MM1218R_RS02185	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS02205	COG3415	Transposase
MM1218R_RS02205	COG2801	Transposase and inactivated derivatives
MM1218R_RS02220	COG1024	Enoyl-CoA hydratase
MM1218R_RS02230	COG0500	methyltransferase
MM1218R_RS02235	COG0297	glycogen (starch) synthase activity
MM1218R_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS02310	COG0657	acetylesterase activity
MM1218R_RS02330	COG4981	capsule polysaccharide biosynthetic process
MM1218R_RS02345	COG1472	Belongs to the glycosyl hydrolase 3 family
MM1218R_RS02360	COG2030	dehydratase
MM1218R_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS02370	COG0183	Belongs to the thiolase family
MM1218R_RS02375	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS02380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MM1218R_RS02400	COG1053	succinate dehydrogenase
MM1218R_RS02415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MM1218R_RS02425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM1218R_RS02425	COG2146	nitrite reductase [NAD(P)H] activity
MM1218R_RS02450	COG2223	nitrite transmembrane transporter activity
MM1218R_RS02460	COG1984	allophanate hydrolase subunit 2
MM1218R_RS02475	COG2223	nitrite transmembrane transporter activity
MM1218R_RS02485	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS02495	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM1218R_RS02515	COG0346	lactoylglutathione lyase activity
MM1218R_RS02540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS02590	COG1404	Belongs to the peptidase S8 family
MM1218R_RS02605	COG4106	trans-aconitate 2-methyltransferase activity
MM1218R_RS02615	COG0778	Nitroreductase
MM1218R_RS02670	COG2130	NADP-dependent
MM1218R_RS02690	COG1070	Carbohydrate kinase
MM1218R_RS02695	COG0246	Mannitol dehydrogenase
MM1218R_RS02720	COG2072	flavoprotein involved in K transport
MM1218R_RS02725	COG2814	Major facilitator Superfamily
MM1218R_RS02740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM1218R_RS02755	COG1082	Xylose isomerase domain protein TIM barrel
MM1218R_RS02775	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS02805	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MM1218R_RS02815	COG0717	Belongs to the dCTP deaminase family
MM1218R_RS02830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM1218R_RS02855	COG3391	amine dehydrogenase activity
MM1218R_RS02860	COG0657	acetylesterase activity
MM1218R_RS02870	COG0247	lactate metabolic process
MM1218R_RS02870	COG2181	nitrate reductase activity
MM1218R_RS02960	COG0443	Heat shock 70 kDa protein
MM1218R_RS02970	COG0484	heat shock protein binding
MM1218R_RS02975	COG0789	Transcriptional regulator
MM1218R_RS02980	COG5651	PPE family
MM1218R_RS03025	COG1024	Enoyl-CoA hydratase
MM1218R_RS03055	COG3360	Dodecin
MM1218R_RS03115	COG4303	Ethanolamine ammonia lyase large subunit
MM1218R_RS03120	COG0531	amino acid
MM1218R_RS03145	COG2239	Acts as a magnesium transporter
MM1218R_RS03175	COG1994	Peptidase M50
MM1218R_RS03185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MM1218R_RS03225	COG1252	NADH dehydrogenase
MM1218R_RS03230	COG0477	Major facilitator Superfamily
MM1218R_RS03245	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MM1218R_RS03250	COG2226	methyltransferase
MM1218R_RS03270	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS03285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS03290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS03295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS03315	COG3321	synthase
MM1218R_RS03315	COG0604	alcohol dehydrogenase
MM1218R_RS03320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM1218R_RS03335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MM1218R_RS03350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM1218R_RS03365	COG0352	thiamine-phosphate diphosphorylase activity
MM1218R_RS03370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MM1218R_RS03380	COG2022	thiamine diphosphate biosynthetic process
MM1218R_RS03405	COG2234	aminopeptidase activity
MM1218R_RS03410	COG2234	aminopeptidase activity
MM1218R_RS03440	COG1309	transcriptional regulator
MM1218R_RS03450	COG0351	phosphomethylpyrimidine kinase
MM1218R_RS03455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MM1218R_RS03500	COG0242	peptide deformylase activity
MM1218R_RS03520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MM1218R_RS03525	COG2186	Transcriptional regulator
MM1218R_RS03540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM1218R_RS03550	COG0688	phosphatidylethanolamine metabolic process
MM1218R_RS03565	COG4221	oxidoreductase activity
MM1218R_RS03575	COG0459	protein refolding
MM1218R_RS03585	COG5651	PPE family
MM1218R_RS03590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MM1218R_RS03605	COG5343	regulation of RNA biosynthetic process
MM1218R_RS03610	COG1595	DNA-templated transcription, initiation
MM1218R_RS03620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS03635	COG1033	growth of symbiont in host cell
MM1218R_RS03635	COG2409	Drug exporters of the RND superfamily
MM1218R_RS03670	COG1024	Enoyl-CoA hydratase
MM1218R_RS03675	COG1505	serine-type exopeptidase activity
MM1218R_RS03750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS03765	COG2733	membrane
MM1218R_RS03790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MM1218R_RS03815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MM1218R_RS03835	COG0438	transferase activity, transferring glycosyl groups
MM1218R_RS03845	COG0588	phosphoglycerate mutase activity
MM1218R_RS03925	COG0204	Acyl-transferase
MM1218R_RS03945	COG2080	2 iron, 2 sulfur cluster binding
MM1218R_RS03950	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MM1218R_RS03955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MM1218R_RS03960	COG0657	acetylesterase activity
MM1218R_RS03985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MM1218R_RS03990	COG0181	hydroxymethylbilane synthase activity
MM1218R_RS04025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS04035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MM1218R_RS04035	COG2124	cytochrome p450
MM1218R_RS04050	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS04060	COG2755	lipolytic protein G-D-S-L family
MM1218R_RS04065	COG2755	lipolytic protein G-D-S-L family
MM1218R_RS04065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MM1218R_RS04075	COG0589	response to stress
MM1218R_RS04090	COG1113	amino acid transport
MM1218R_RS04100	COG4948	Mandelate Racemase Muconate Lactonizing
MM1218R_RS04115	COG1403	HNH endonuclease
MM1218R_RS04120	COG0531	amino acid
MM1218R_RS04125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MM1218R_RS04130	COG0406	alpha-ribazole phosphatase activity
MM1218R_RS04140	COG0785	Cytochrome C biogenesis protein
MM1218R_RS04150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MM1218R_RS04170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM1218R_RS04180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MM1218R_RS04185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM1218R_RS04245	COG4221	oxidoreductase activity
MM1218R_RS04260	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS04265	COG1228	amidohydrolase
MM1218R_RS04270	COG4948	Mandelate Racemase Muconate Lactonizing
MM1218R_RS04280	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MM1218R_RS04310	COG2226	methyltransferase
MM1218R_RS04330	COG0142	geranyltranstransferase activity
MM1218R_RS04335	COG0501	Belongs to the peptidase M48B family
MM1218R_RS04340	COG0659	secondary active sulfate transmembrane transporter activity
MM1218R_RS04345	COG0659	secondary active sulfate transmembrane transporter activity
MM1218R_RS04355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM1218R_RS04375	COG1666	GTP binding
MM1218R_RS04390	COG0577	efflux transmembrane transporter activity
MM1218R_RS04390	COG1136	(ABC) transporter
MM1218R_RS04435	COG5651	PPE family
MM1218R_RS04435	COG5263	repeat protein
MM1218R_RS04445	COG2345	Transcriptional regulator
MM1218R_RS04460	COG0154	amidase activity
MM1218R_RS04490	COG0657	acetylesterase activity
MM1218R_RS04510	COG2267	carboxylic ester hydrolase activity
MM1218R_RS04530	COG3537	Alpha-1,2-mannosidase
MM1218R_RS04545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS04550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MM1218R_RS04555	COG1074	ATP-dependent DNA helicase activity
MM1218R_RS04560	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MM1218R_RS04575	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM1218R_RS04590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM1218R_RS04610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MM1218R_RS04615	COG2030	dehydratase
MM1218R_RS04620	COG2030	dehydratase
MM1218R_RS04625	COG2030	dehydratase
MM1218R_RS04635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MM1218R_RS04645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MM1218R_RS04650	COG0081	regulation of translation
MM1218R_RS04655	COG4941	Belongs to the sigma-70 factor family
MM1218R_RS04665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS04670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS04675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS04680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS04720	COG3415	Transposase
MM1218R_RS04720	COG2801	Transposase and inactivated derivatives
MM1218R_RS04735	COG0222	ribosome binding
MM1218R_RS04755	COG0085	RNA polymerase activity
MM1218R_RS04760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MM1218R_RS04780	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MM1218R_RS04790	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS04820	COG1510	regulation of RNA biosynthetic process
MM1218R_RS04835	COG1309	transcriptional regulator
MM1218R_RS04845	COG0049	tRNA binding
MM1218R_RS04850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MM1218R_RS04855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MM1218R_RS04890	COG0535	radical SAM domain protein
MM1218R_RS04920	COG1309	transcriptional regulator
MM1218R_RS04930	COG5651	PPE family
MM1218R_RS04930	COG5263	repeat protein
MM1218R_RS04950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MM1218R_RS04955	COG0088	Forms part of the polypeptide exit tunnel
MM1218R_RS04960	COG0089	rRNA binding
MM1218R_RS04965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MM1218R_RS04970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MM1218R_RS04975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MM1218R_RS04980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MM1218R_RS04985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MM1218R_RS04990	COG0255	Belongs to the universal ribosomal protein uL29 family
MM1218R_RS04995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MM1218R_RS05020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MM1218R_RS05030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MM1218R_RS05035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MM1218R_RS05045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM1218R_RS05050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MM1218R_RS05055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MM1218R_RS05060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MM1218R_RS05065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MM1218R_RS05070	COG1841	ribosomal large subunit assembly
MM1218R_RS05075	COG0200	Binds to the 23S rRNA
MM1218R_RS05080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS05085	COG0616	signal peptide processing
MM1218R_RS05090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS05095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS05100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS05105	COG0300	oxidoreductase activity
MM1218R_RS05110	COG1063	alcohol dehydrogenase
MM1218R_RS05115	COG2226	methyltransferase
MM1218R_RS05130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM1218R_RS05135	COG1070	Carbohydrate kinase
MM1218R_RS05145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS05150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS05160	COG0563	adenylate kinase activity
MM1218R_RS05195	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS05205	COG0477	Major facilitator Superfamily
MM1218R_RS05230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MM1218R_RS05235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MM1218R_RS05240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MM1218R_RS05245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MM1218R_RS05250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MM1218R_RS05255	COG0202	RNA polymerase activity
MM1218R_RS05260	COG0203	ribosomal protein L17
MM1218R_RS05270	COG1113	amino acid transport
MM1218R_RS05275	COG5651	PPE family
MM1218R_RS05315	COG1404	Belongs to the peptidase S8 family
MM1218R_RS05335	COG4842	Belongs to the WXG100 family
MM1218R_RS05340	COG4842	Belongs to the WXG100 family
MM1218R_RS05345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MM1218R_RS05350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MM1218R_RS05355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM1218R_RS05370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS05405	COG0076	glutamate decarboxylase activity
MM1218R_RS05410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MM1218R_RS05430	COG0456	acetyltransferase
MM1218R_RS05435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MM1218R_RS05440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MM1218R_RS05445	COG0459	protein refolding
MM1218R_RS05450	COG2508	Transcriptional regulator
MM1218R_RS05470	COG1228	amidohydrolase
MM1218R_RS05510	COG5651	PPE family
MM1218R_RS05550	COG0477	Major facilitator Superfamily
MM1218R_RS05555	COG1733	regulation of RNA biosynthetic process
MM1218R_RS05560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MM1218R_RS05560	COG0519	Catalyzes the synthesis of GMP from XMP
MM1218R_RS05590	COG0406	alpha-ribazole phosphatase activity
MM1218R_RS05595	COG2030	dehydratase
MM1218R_RS05600	COG0561	phosphatase activity
MM1218R_RS05600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM1218R_RS05605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS05625	COG3391	amine dehydrogenase activity
MM1218R_RS05630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MM1218R_RS05645	COG2018	Roadblock/LC7 domain
MM1218R_RS05660	COG1357	PFAM Pentapeptide repeats (8 copies)
MM1218R_RS05665	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS05670	COG0156	8-amino-7-oxononanoate synthase activity
MM1218R_RS05680	COG1716	ATPase activity
MM1218R_RS05680	COG1131	(ABC) transporter
MM1218R_RS05680	COG0842	Transport permease protein
MM1218R_RS05685	COG0842	Transport permease protein
MM1218R_RS05685	COG1716	ATPase activity
MM1218R_RS05685	COG1131	(ABC) transporter
MM1218R_RS05700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MM1218R_RS05715	COG0277	FAD linked oxidase domain protein
MM1218R_RS05740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MM1218R_RS05745	COG2873	o-acetylhomoserine
MM1218R_RS05765	COG1295	ribonuclease BN
MM1218R_RS05770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MM1218R_RS05775	COG2814	Major facilitator Superfamily
MM1218R_RS05780	COG1686	Belongs to the peptidase S11 family
MM1218R_RS05800	COG1595	DNA-templated transcription, initiation
MM1218R_RS05805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM1218R_RS05820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MM1218R_RS05825	COG1053	succinate dehydrogenase
MM1218R_RS05835	COG2009	succinate dehydrogenase
MM1218R_RS05850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MM1218R_RS05870	COG4266	Belongs to the allantoicase family
MM1218R_RS05880	COG1953	Uracil, thiamine, allantoin
MM1218R_RS05885	COG1403	HNH endonuclease
MM1218R_RS05900	COG3511	phospholipase C
MM1218R_RS05905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MM1218R_RS05910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM1218R_RS05925	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MM1218R_RS05925	COG1473	amidohydrolase
MM1218R_RS05955	COG0069	glutamate synthase activity
MM1218R_RS05965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MM1218R_RS05975	COG0598	Magnesium transport protein CorA
MM1218R_RS05980	COG0564	pseudouridine synthase activity
MM1218R_RS05985	COG3408	Glycogen debranching enzyme
MM1218R_RS05985	COG3119	arylsulfatase activity
MM1218R_RS05995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MM1218R_RS06000	COG5651	PPE family
MM1218R_RS06015	COG1201	RNA secondary structure unwinding
MM1218R_RS06020	COG1309	transcriptional regulator
MM1218R_RS06025	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS06035	COG1522	sequence-specific DNA binding
MM1218R_RS06075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS06080	COG4770	biotin carboxylase activity
MM1218R_RS06095	COG0424	maF-like protein
MM1218R_RS06105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM1218R_RS06110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MM1218R_RS06110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MM1218R_RS06150	COG0659	secondary active sulfate transmembrane transporter activity
MM1218R_RS06155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS06165	COG2936	dipeptidyl-peptidase activity
MM1218R_RS06190	COG1316	TRANSCRIPTIONal
MM1218R_RS06225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MM1218R_RS06250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM1218R_RS06260	COG1482	cell wall glycoprotein biosynthetic process
MM1218R_RS06265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM1218R_RS06270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM1218R_RS06275	COG0531	amino acid
MM1218R_RS06280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MM1218R_RS06300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MM1218R_RS06330	COG5401	PFAM Sporulation and spore germination
MM1218R_RS06340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MM1218R_RS06345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MM1218R_RS06350	COG0653	protein targeting
MM1218R_RS06360	COG2020	methyltransferase activity
MM1218R_RS06370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MM1218R_RS06370	COG4651	solute:proton antiporter activity
MM1218R_RS06385	COG2326	polyphosphate kinase activity
MM1218R_RS06410	COG0183	Belongs to the thiolase family
MM1218R_RS06420	COG1162	GTPase activity
MM1218R_RS06425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MM1218R_RS06430	COG2135	peptidase activity
MM1218R_RS06485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MM1218R_RS06490	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS06510	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MM1218R_RS06545	COG0406	alpha-ribazole phosphatase activity
MM1218R_RS06560	COG0513	Belongs to the DEAD box helicase family
MM1218R_RS06605	COG0596	Alpha beta hydrolase
MM1218R_RS06665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MM1218R_RS06690	COG1615	UPF0182 protein
MM1218R_RS06710	COG3119	arylsulfatase activity
MM1218R_RS06725	COG1396	sequence-specific DNA binding
MM1218R_RS06725	COG3800	Transcriptional regulator
MM1218R_RS06735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MM1218R_RS06780	COG2267	carboxylic ester hydrolase activity
MM1218R_RS06795	COG0657	acetylesterase activity
MM1218R_RS06830	COG0714	Associated with various cellular activities
MM1218R_RS06870	COG0713	ATP synthesis coupled electron transport
MM1218R_RS06880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MM1218R_RS06885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MM1218R_RS06890	COG1034	ATP synthesis coupled electron transport
MM1218R_RS06905	COG0649	NAD binding
MM1218R_RS06910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MM1218R_RS06915	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MM1218R_RS06940	COG2353	YceI-like domain
MM1218R_RS06970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM1218R_RS06975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS06995	COG3321	synthase
MM1218R_RS06995	COG0604	alcohol dehydrogenase
MM1218R_RS07000	COG0604	alcohol dehydrogenase
MM1218R_RS07015	COG2267	carboxylic ester hydrolase activity
MM1218R_RS07030	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MM1218R_RS07035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM1218R_RS07045	COG0028	Belongs to the TPP enzyme family
MM1218R_RS07110	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS07120	COG0483	inositol monophosphate 1-phosphatase activity
MM1218R_RS07185	COG0277	FAD linked oxidase domain protein
MM1218R_RS07190	COG0493	'glutamate synthase
MM1218R_RS07195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MM1218R_RS07200	COG0668	transmembrane transport
MM1218R_RS07210	COG2884	Cell division ATP-binding protein ftsE
MM1218R_RS07215	COG2177	Part of the ABC transporter FtsEX involved in
MM1218R_RS07220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MM1218R_RS07235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM1218R_RS07255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MM1218R_RS07440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM1218R_RS07725	COG0657	acetylesterase activity
MM1218R_RS07730	COG2066	Belongs to the glutaminase family
MM1218R_RS07740	COG5651	PPE family
MM1218R_RS07770	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS07780	COG2130	NADP-dependent
MM1218R_RS07790	COG3956	TIGRFAM MazG family protein
MM1218R_RS07795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MM1218R_RS07800	COG1611	Belongs to the LOG family
MM1218R_RS07810	COG2124	cytochrome p450
MM1218R_RS07815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS07820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM1218R_RS07825	COG2354	Protein conserved in bacteria
MM1218R_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS07835	COG1309	transcriptional regulator
MM1218R_RS07855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MM1218R_RS07900	COG2508	Transcriptional regulator
MM1218R_RS07905	COG2301	Belongs to the HpcH HpaI aldolase family
MM1218R_RS07960	COG0657	acetylesterase activity
MM1218R_RS07970	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS07995	COG0657	acetylesterase activity
MM1218R_RS08005	COG2508	Transcriptional regulator
MM1218R_RS08020	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS08025	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS08030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MM1218R_RS08050	COG2076	Multidrug Resistance protein
MM1218R_RS08075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MM1218R_RS08080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM1218R_RS08090	COG1966	Carbon starvation protein
MM1218R_RS08095	COG2132	Multicopper oxidase
MM1218R_RS08120	COG1793	dna ligase
MM1218R_RS08130	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS08135	COG1733	regulation of RNA biosynthetic process
MM1218R_RS08155	COG2186	Transcriptional regulator
MM1218R_RS08195	COG5263	repeat protein
MM1218R_RS08195	COG5651	PPE family
MM1218R_RS08215	COG1309	transcriptional regulator
MM1218R_RS08260	COG0560	Phosphoserine phosphatase
MM1218R_RS08260	COG3830	Belongs to the UPF0237 family
MM1218R_RS08270	COG3260	NADH ubiquinone oxidoreductase 20
MM1218R_RS08280	COG0650	Formate hydrogenlyase subunit 4
MM1218R_RS08290	COG0651	ATP synthesis coupled electron transport
MM1218R_RS08295	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MM1218R_RS08295	COG3261	NADH dehydrogenase
MM1218R_RS08300	COG1119	ATPase activity
MM1218R_RS08335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MM1218R_RS08340	COG0110	maltose O-acetyltransferase activity
MM1218R_RS08355	COG0415	Belongs to the DNA photolyase family
MM1218R_RS08365	COG2409	Drug exporters of the RND superfamily
MM1218R_RS08400	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS08425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MM1218R_RS08450	COG0482	sulfurtransferase activity
MM1218R_RS08470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MM1218R_RS08495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MM1218R_RS08500	COG0154	amidase activity
MM1218R_RS08505	COG0205	6-phosphofructokinase activity
MM1218R_RS08525	COG2259	Doxx family
MM1218R_RS08545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MM1218R_RS08550	COG0655	NAD(P)H dehydrogenase (quinone) activity
MM1218R_RS08565	COG0473	3-isopropylmalate dehydrogenase activity
MM1218R_RS08570	COG2271	Major facilitator Superfamily
MM1218R_RS08575	COG0179	Fumarylacetoacetate (FAA) hydrolase
MM1218R_RS08580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MM1218R_RS08615	COG0156	8-amino-7-oxononanoate synthase activity
MM1218R_RS08625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MM1218R_RS08630	COG0066	3-isopropylmalate dehydratase activity
MM1218R_RS08645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MM1218R_RS08650	COG1920	GTP binding
MM1218R_RS08665	COG1181	Belongs to the D-alanine--D-alanine ligase family
MM1218R_RS08685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MM1218R_RS08720	COG0656	L-ascorbic acid biosynthetic process
MM1218R_RS08730	COG0657	acetylesterase activity
MM1218R_RS08745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MM1218R_RS08750	COG0742	ribosomal rna small subunit methyltransferase
MM1218R_RS08755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MM1218R_RS08770	COG0701	Predicted permease
MM1218R_RS08790	COG3268	Saccharopine dehydrogenase
MM1218R_RS08800	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS08805	COG3161	chorismate lyase activity
MM1218R_RS08810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM1218R_RS08810	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS08815	COG3321	synthase
MM1218R_RS08815	COG0604	alcohol dehydrogenase
MM1218R_RS08835	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS08845	COG2226	methyltransferase
MM1218R_RS08860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS08890	COG0604	alcohol dehydrogenase
MM1218R_RS08890	COG3321	synthase
MM1218R_RS08905	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS08910	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MM1218R_RS08920	COG3599	regulation of cell shape
MM1218R_RS08935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MM1218R_RS08950	COG1305	Transglutaminase-like
MM1218R_RS08990	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MM1218R_RS09030	COG1686	Belongs to the peptidase S11 family
MM1218R_RS09040	COG0228	four-way junction DNA binding
MM1218R_RS09050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MM1218R_RS09055	COG0336	Belongs to the RNA methyltransferase TrmD family
MM1218R_RS09065	COG0335	large ribosomal subunit rRNA binding
MM1218R_RS09075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MM1218R_RS09105	COG0792	nuclease activity
MM1218R_RS09145	COG0052	Belongs to the universal ribosomal protein uS2 family
MM1218R_RS09150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MM1218R_RS09155	COG0154	amidase activity
MM1218R_RS09175	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS09185	COG0233	cytoplasmic translational termination
MM1218R_RS09195	COG0657	acetylesterase activity
MM1218R_RS09200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MM1218R_RS09230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MM1218R_RS09270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MM1218R_RS09330	COG0409	Hydrogenase expression formation protein
MM1218R_RS09340	COG0309	Hydrogenase expression formation protein (HypE)
MM1218R_RS09345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MM1218R_RS09355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MM1218R_RS09405	COG0375	protein maturation
MM1218R_RS09410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MM1218R_RS09450	COG0579	oxidoreductase
MM1218R_RS09480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MM1218R_RS09480	COG1648	precorrin-2 dehydrogenase activity
MM1218R_RS09490	COG0442	prolyl-tRNA aminoacylation
MM1218R_RS09505	COG0779	Required for maturation of 30S ribosomal subunits
MM1218R_RS09520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MM1218R_RS09520	COG0481	GTPase activity
MM1218R_RS09525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MM1218R_RS09530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM1218R_RS09545	COG0395	ABC-type sugar transport system, permease component
MM1218R_RS09555	COG3842	ATPase activity
MM1218R_RS09565	COG1024	Enoyl-CoA hydratase
MM1218R_RS09570	COG5651	PPE family
MM1218R_RS09590	COG1554	hydrolase, family 65, central catalytic
MM1218R_RS09625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MM1218R_RS09630	COG2977	Belongs to the P-Pant transferase superfamily
MM1218R_RS09635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MM1218R_RS09640	COG0183	Belongs to the thiolase family
MM1218R_RS09645	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS09660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MM1218R_RS09675	COG1185	polyribonucleotide nucleotidyltransferase activity
MM1218R_RS09690	COG0686	Belongs to the AlaDH PNT family
MM1218R_RS09695	COG1522	sequence-specific DNA binding
MM1218R_RS09735	COG1403	HNH endonuclease
MM1218R_RS09740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MM1218R_RS09780	COG4770	biotin carboxylase activity
MM1218R_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS09795	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS09800	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS09810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MM1218R_RS09820	COG3214	Protein conserved in bacteria
MM1218R_RS09825	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MM1218R_RS09835	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MM1218R_RS09850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS09870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MM1218R_RS09885	COG1842	Phage shock protein A
MM1218R_RS09895	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MM1218R_RS09915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MM1218R_RS09920	COG2137	regulation of response to DNA damage stimulus
MM1218R_RS09925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM1218R_RS09935	COG1196	nuclear chromosome segregation
MM1218R_RS09960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MM1218R_RS09965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MM1218R_RS09970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MM1218R_RS09975	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS09990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MM1218R_RS09995	COG1388	LysM domain
MM1218R_RS10000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MM1218R_RS10005	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MM1218R_RS10115	COG0756	dUTP diphosphatase activity
MM1218R_RS10145	COG0569	domain protein
MM1218R_RS10150	COG0531	amino acid
MM1218R_RS10155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM1218R_RS10180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM1218R_RS10195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MM1218R_RS10225	COG1024	Enoyl-CoA hydratase
MM1218R_RS10230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MM1218R_RS10250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MM1218R_RS10295	COG2267	carboxylic ester hydrolase activity
MM1218R_RS10330	COG0657	acetylesterase activity
MM1218R_RS10340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM1218R_RS10345	COG0798	PFAM Bile acid sodium symporter
MM1218R_RS10370	COG0753	catalase activity
MM1218R_RS10375	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS10430	COG1022	Amp-dependent synthetase and ligase
MM1218R_RS10475	COG2223	nitrite transmembrane transporter activity
MM1218R_RS10500	COG2070	2-Nitropropane dioxygenase
MM1218R_RS10510	COG0667	Aldo Keto reductase
MM1218R_RS10520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MM1218R_RS10530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MM1218R_RS10550	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MM1218R_RS10555	COG1946	Acyl-CoA thioesterase
MM1218R_RS10560	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MM1218R_RS10565	COG0217	transcriptional regulatory protein
MM1218R_RS10570	COG2508	Transcriptional regulator
MM1218R_RS10615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MM1218R_RS10620	COG0632	four-way junction helicase activity
MM1218R_RS10625	COG2255	four-way junction helicase activity
MM1218R_RS10650	COG0657	acetylesterase activity
MM1218R_RS10655	COG1022	Amp-dependent synthetase and ligase
MM1218R_RS10655	COG3320	Male sterility
MM1218R_RS10675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MM1218R_RS10680	COG0747	negative chemotaxis
MM1218R_RS10685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM1218R_RS10690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MM1218R_RS10705	COG0124	histidyl-tRNA synthetase
MM1218R_RS10735	COG1396	sequence-specific DNA binding
MM1218R_RS10740	COG0235	Class ii aldolase
MM1218R_RS10745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MM1218R_RS10820	COG0432	Pfam Uncharacterised protein family UPF0047
MM1218R_RS10825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MM1218R_RS10830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MM1218R_RS10835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MM1218R_RS10840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MM1218R_RS10850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MM1218R_RS10855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MM1218R_RS10875	COG0006	proline dipeptidase activity
MM1218R_RS10880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MM1218R_RS10940	COG2226	methyltransferase
MM1218R_RS10950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MM1218R_RS10955	COG0540	Belongs to the ATCase OTCase family
MM1218R_RS10970	COG0505	Belongs to the CarA family
MM1218R_RS10980	COG0284	orotidine-5'-phosphate decarboxylase activity
MM1218R_RS11005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MM1218R_RS11015	COG2072	flavoprotein involved in K transport
MM1218R_RS11025	COG0657	acetylesterase activity
MM1218R_RS11055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MM1218R_RS11090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM1218R_RS11090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM1218R_RS11095	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MM1218R_RS11115	COG0322	excinuclease ABC activity
MM1218R_RS11120	COG1660	Displays ATPase and GTPase activities
MM1218R_RS11130	COG1481	regulation of sporulation
MM1218R_RS11140	COG0657	acetylesterase activity
MM1218R_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS11155	COG3391	amine dehydrogenase activity
MM1218R_RS11155	COG5651	PPE family
MM1218R_RS11180	COG0126	phosphoglycerate kinase activity
MM1218R_RS11185	COG0149	triose-phosphate isomerase activity
MM1218R_RS11190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MM1218R_RS11195	COG0531	amino acid
MM1218R_RS11215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MM1218R_RS11220	COG0657	acetylesterase activity
MM1218R_RS11245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MM1218R_RS11255	COG0109	protoheme IX farnesyltransferase activity
MM1218R_RS11260	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
MM1218R_RS11295	COG1131	(ABC) transporter
MM1218R_RS11320	COG0396	ATPase activity
MM1218R_RS11330	COG0822	iron-sulfur transferase activity
MM1218R_RS11335	COG2151	metal-sulfur cluster biosynthetic enzyme
MM1218R_RS11345	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS11365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM1218R_RS11375	COG0488	(ABC) transporter
MM1218R_RS11385	COG1309	transcriptional regulator
MM1218R_RS11390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MM1218R_RS11400	COG3883	PFAM NLP P60 protein
MM1218R_RS11400	COG0791	NLP P60 protein
MM1218R_RS11410	COG0714	Associated with various cellular activities
MM1218R_RS11420	COG2304	oxidoreductase activity
MM1218R_RS11435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MM1218R_RS11465	COG1309	transcriptional regulator
MM1218R_RS11475	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS11480	COG2205	protein histidine kinase activity
MM1218R_RS11510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS11515	COG3360	Dodecin
MM1218R_RS11535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MM1218R_RS11565	COG1309	transcriptional regulator
MM1218R_RS11570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS11585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MM1218R_RS11595	COG4106	trans-aconitate 2-methyltransferase activity
MM1218R_RS11625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MM1218R_RS11630	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS11645	COG0463	Glycosyl transferase, family 2
MM1218R_RS11650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MM1218R_RS11665	COG2246	polysaccharide biosynthetic process
MM1218R_RS11675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MM1218R_RS11680	COG3321	synthase
MM1218R_RS11680	COG0604	alcohol dehydrogenase
MM1218R_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS11700	COG0604	alcohol dehydrogenase
MM1218R_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS11700	COG3321	synthase
MM1218R_RS11710	COG2070	2-Nitropropane dioxygenase
MM1218R_RS11725	COG2226	methyltransferase
MM1218R_RS11740	COG1819	glycosyl
MM1218R_RS11780	COG0252	asparaginase activity
MM1218R_RS11795	COG2226	methyltransferase
MM1218R_RS11815	COG0300	oxidoreductase activity
MM1218R_RS11885	COG3883	PFAM NLP P60 protein
MM1218R_RS11885	COG0791	NLP P60 protein
MM1218R_RS11900	COG0156	8-amino-7-oxononanoate synthase activity
MM1218R_RS11905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MM1218R_RS11915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MM1218R_RS11965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MM1218R_RS11970	COG0131	Imidazoleglycerol-phosphate dehydratase
MM1218R_RS11975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MM1218R_RS11980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MM1218R_RS11985	COG0483	inositol monophosphate 1-phosphatase activity
MM1218R_RS11990	COG0107	imidazoleglycerol-phosphate synthase activity
MM1218R_RS11995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MM1218R_RS12015	COG0189	ligase activity
MM1218R_RS12015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MM1218R_RS12020	COG0531	amino acid
MM1218R_RS12035	COG0387	Pfam Sodium calcium exchanger
MM1218R_RS12055	COG0134	indole-3-glycerol-phosphate synthase activity
MM1218R_RS12065	COG0159	tryptophan synthase activity
MM1218R_RS12095	COG1946	Acyl-CoA thioesterase
MM1218R_RS12100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MM1218R_RS12100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MM1218R_RS12105	COG1132	(ABC) transporter
MM1218R_RS12110	COG4988	ABC transporter
MM1218R_RS12115	COG1294	oxidase, subunit
MM1218R_RS12120	COG1271	oxidase subunit
MM1218R_RS12180	COG0556	nucleotide-excision repair
MM1218R_RS12205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM1218R_RS12220	COG1842	Phage shock protein A
MM1218R_RS12230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MM1218R_RS12230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MM1218R_RS12240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MM1218R_RS12245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MM1218R_RS12250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM1218R_RS12275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MM1218R_RS12280	COG0072	phenylalanine-tRNA ligase activity
MM1218R_RS12280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM1218R_RS12285	COG0657	acetylesterase activity
MM1218R_RS12290	COG3391	amine dehydrogenase activity
MM1218R_RS12295	COG0657	acetylesterase activity
MM1218R_RS12330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MM1218R_RS12340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MM1218R_RS12345	COG1438	arginine binding
MM1218R_RS12350	COG0137	argininosuccinate synthase activity
MM1218R_RS12355	COG0165	Argininosuccinate lyase
MM1218R_RS12365	COG0604	alcohol dehydrogenase
MM1218R_RS12365	COG3321	synthase
MM1218R_RS12370	COG0604	alcohol dehydrogenase
MM1218R_RS12370	COG3321	synthase
MM1218R_RS12375	COG3321	synthase
MM1218R_RS12375	COG3321	synthase
MM1218R_RS12375	COG0604	alcohol dehydrogenase
MM1218R_RS12375	COG0604	alcohol dehydrogenase
MM1218R_RS12390	COG0488	(ABC) transporter
MM1218R_RS12440	COG2835	tetraacyldisaccharide 4'-kinase activity
MM1218R_RS12480	COG2094	Belongs to the DNA glycosylase MPG family
MM1218R_RS12505	COG3391	amine dehydrogenase activity
MM1218R_RS12530	COG0647	UMP catabolic process
MM1218R_RS12565	COG0504	CTP synthase activity
MM1218R_RS12570	COG0494	nUDIX hydrolase
MM1218R_RS12590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MM1218R_RS12620	COG0477	Major facilitator Superfamily
MM1218R_RS12625	COG5651	PPE family
MM1218R_RS12645	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS12665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MM1218R_RS12670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MM1218R_RS12685	COG1160	GTP binding
MM1218R_RS12695	COG4974	Belongs to the 'phage' integrase family
MM1218R_RS12720	COG2818	Glycosylase
MM1218R_RS12725	COG0183	Belongs to the thiolase family
MM1218R_RS12730	COG0656	L-ascorbic acid biosynthetic process
MM1218R_RS12740	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS12745	COG0656	L-ascorbic acid biosynthetic process
MM1218R_RS12790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS12795	COG2188	Transcriptional regulator
MM1218R_RS12800	COG0142	geranyltranstransferase activity
MM1218R_RS12810	COG2801	Transposase and inactivated derivatives
MM1218R_RS12810	COG3415	Transposase
MM1218R_RS12825	COG0438	transferase activity, transferring glycosyl groups
MM1218R_RS12850	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS12860	COG1278	Cold shock
MM1218R_RS12875	COG0058	SHG alpha-glucan phosphorylase activity
MM1218R_RS12890	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS12905	COG2271	Major facilitator Superfamily
MM1218R_RS12925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MM1218R_RS12930	COG0531	amino acid
MM1218R_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS13005	COG1914	H( )-stimulated, divalent metal cation uptake system
MM1218R_RS13020	COG0657	acetylesterase activity
MM1218R_RS13045	COG2508	Transcriptional regulator
MM1218R_RS13065	COG0243	molybdopterin cofactor binding
MM1218R_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS13100	COG1716	ATPase activity
MM1218R_RS13100	COG0842	Transport permease protein
MM1218R_RS13100	COG1131	(ABC) transporter
MM1218R_RS13120	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS13125	COG0235	Class ii aldolase
MM1218R_RS13135	COG3415	Transposase
MM1218R_RS13135	COG2801	Transposase and inactivated derivatives
MM1218R_RS13155	COG0300	oxidoreductase activity
MM1218R_RS13165	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS13180	COG3415	Transposase
MM1218R_RS13180	COG2801	Transposase and inactivated derivatives
MM1218R_RS13265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM1218R_RS13270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MM1218R_RS13275	COG1937	Protein conserved in bacteria
MM1218R_RS13325	COG0657	acetylesterase activity
MM1218R_RS13340	COG0657	acetylesterase activity
MM1218R_RS13345	COG1335	isochorismatase
MM1218R_RS13380	COG3266	domain, Protein
MM1218R_RS13385	COG1674	ftsk spoiiie
MM1218R_RS13400	COG5651	PPE family
MM1218R_RS13410	COG5651	PPE family
MM1218R_RS13445	COG1404	Belongs to the peptidase S8 family
MM1218R_RS13455	COG0464	growth
MM1218R_RS13455	COG0457	Tetratricopeptide repeat
MM1218R_RS13495	COG1285	pathogenesis
MM1218R_RS13545	COG0653	protein targeting
MM1218R_RS13620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MM1218R_RS13635	COG1253	flavin adenine dinucleotide binding
MM1218R_RS13645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MM1218R_RS13665	COG0831	urea catabolic process
MM1218R_RS13670	COG0832	Belongs to the urease beta subunit family
MM1218R_RS13675	COG0804	urea catabolic process
MM1218R_RS13680	COG0830	nickel cation binding
MM1218R_RS13685	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MM1218R_RS13695	COG1252	NADH dehydrogenase
MM1218R_RS13700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS13745	COG2261	transglycosylase associated protein
MM1218R_RS13765	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MM1218R_RS13770	COG4221	oxidoreductase activity
MM1218R_RS13780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS13790	COG0183	Belongs to the thiolase family
MM1218R_RS13830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM1218R_RS13855	COG1024	Enoyl-CoA hydratase
MM1218R_RS13890	COG0154	amidase activity
MM1218R_RS13895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS13920	COG2801	Transposase and inactivated derivatives
MM1218R_RS13920	COG3415	Transposase
MM1218R_RS13945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS13955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MM1218R_RS14000	COG2070	2-Nitropropane dioxygenase
MM1218R_RS14030	COG1063	alcohol dehydrogenase
MM1218R_RS14035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS14040	COG1490	D-aminoacyl-tRNA deacylase activity
MM1218R_RS14065	COG1546	Belongs to the CinA family
MM1218R_RS14065	COG1058	Belongs to the CinA family
MM1218R_RS14080	COG1950	PFAM Membrane protein of
MM1218R_RS14085	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS14120	COG1309	transcriptional regulator
MM1218R_RS14165	COG0640	Transcriptional regulator
MM1218R_RS14190	COG5651	PPE family
MM1218R_RS14190	COG5263	repeat protein
MM1218R_RS14215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS14220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS14250	COG2319	Wd-40 repeat
MM1218R_RS14250	COG3903	Transcriptional regulator
MM1218R_RS14315	COG0450	alkyl hydroperoxide reductase
MM1218R_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS14365	COG4977	sequence-specific DNA binding
MM1218R_RS14370	COG2031	fatty acid transporter
MM1218R_RS14395	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS14400	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS14405	COG1024	Enoyl-CoA hydratase
MM1218R_RS14420	COG0543	2 iron, 2 sulfur cluster binding
MM1218R_RS14420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MM1218R_RS14425	COG0596	Alpha beta hydrolase
MM1218R_RS14435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM1218R_RS14435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MM1218R_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS14455	COG2076	Multidrug Resistance protein
MM1218R_RS14460	COG1309	transcriptional regulator
MM1218R_RS14470	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS14475	COG2197	response regulator
MM1218R_RS14495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS14500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS14525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MM1218R_RS14580	COG5651	PPE family
MM1218R_RS14610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MM1218R_RS14625	COG2130	NADP-dependent
MM1218R_RS14630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS14640	COG0501	Belongs to the peptidase M48B family
MM1218R_RS14660	COG1872	DUF167
MM1218R_RS14680	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MM1218R_RS14700	COG3757	hydrolase, family 25
MM1218R_RS14715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS14740	COG2226	methyltransferase
MM1218R_RS14745	COG0438	transferase activity, transferring glycosyl groups
MM1218R_RS14770	COG2124	cytochrome p450
MM1218R_RS14785	COG3391	amine dehydrogenase activity
MM1218R_RS14800	COG1022	Amp-dependent synthetase and ligase
MM1218R_RS14800	COG3320	Male sterility
MM1218R_RS14810	COG0778	Nitroreductase
MM1218R_RS14855	COG1643	Atp-dependent helicase
MM1218R_RS14860	COG3391	amine dehydrogenase activity
MM1218R_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS14875	COG0604	alcohol dehydrogenase
MM1218R_RS14875	COG3321	synthase
MM1218R_RS14885	COG1192	Involved in chromosome partitioning
MM1218R_RS14910	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM1218R_RS14960	COG1742	UPF0060 membrane protein
MM1218R_RS14970	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MM1218R_RS14975	COG0477	Major facilitator Superfamily
MM1218R_RS15000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS15015	COG1024	Enoyl-CoA hydratase
MM1218R_RS15090	COG0456	acetyltransferase
MM1218R_RS15100	COG0789	Transcriptional regulator
MM1218R_RS15110	COG0302	gtp cyclohydrolase
MM1218R_RS15180	COG5651	PPE family
MM1218R_RS15190	COG0657	acetylesterase activity
MM1218R_RS15195	COG1752	Esterase of the alpha-beta hydrolase superfamily
MM1218R_RS15200	COG3842	ATPase activity
MM1218R_RS15205	COG0395	ABC-type sugar transport system, permease component
MM1218R_RS15210	COG1175	transmembrane transport
MM1218R_RS15225	COG1335	isochorismatase
MM1218R_RS15235	COG3265	gluconokinase activity
MM1218R_RS15245	COG2272	Belongs to the type-B carboxylesterase lipase family
MM1218R_RS15265	COG3781	membrane
MM1218R_RS15275	COG0604	alcohol dehydrogenase
MM1218R_RS15275	COG3321	synthase
MM1218R_RS15300	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MM1218R_RS15350	COG0300	oxidoreductase activity
MM1218R_RS15400	COG2367	Beta-lactamase
MM1218R_RS15425	COG0300	oxidoreductase activity
MM1218R_RS15540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM1218R_RS15555	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MM1218R_RS15560	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MM1218R_RS15565	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MM1218R_RS15595	COG1222	aaa ATPase
MM1218R_RS15630	COG0604	alcohol dehydrogenase
MM1218R_RS15630	COG3321	synthase
MM1218R_RS15640	COG0477	Major facilitator Superfamily
MM1218R_RS15660	COG0140	phosphoribosyl-ATP diphosphatase activity
MM1218R_RS15670	COG5651	PPE family
MM1218R_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS15700	COG0215	cysteine-tRNA ligase activity
MM1218R_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS15730	COG1968	undecaprenyl-diphosphatase activity
MM1218R_RS15750	COG0167	dihydroorotate dehydrogenase activity
MM1218R_RS15755	COG1403	HNH endonuclease
MM1218R_RS15765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM1218R_RS15835	COG1074	ATP-dependent DNA helicase activity
MM1218R_RS15880	COG2226	methyltransferase
MM1218R_RS15910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS15910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS15915	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MM1218R_RS15960	COG1799	cell septum assembly
MM1218R_RS15975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MM1218R_RS15985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MM1218R_RS15990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM1218R_RS16005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM1218R_RS16010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MM1218R_RS16025	COG0768	penicillin binding
MM1218R_RS16035	COG0275	rRNA processing
MM1218R_RS16040	COG2001	Belongs to the MraZ family
MM1218R_RS16050	COG0456	acetyltransferase
MM1218R_RS16065	COG0142	geranyltranstransferase activity
MM1218R_RS16085	COG0142	geranyltranstransferase activity
MM1218R_RS16090	COG3425	synthase
MM1218R_RS16110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MM1218R_RS16115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MM1218R_RS16120	COG0142	geranyltranstransferase activity
MM1218R_RS16135	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MM1218R_RS16165	COG0003	Pfam Anion-transporting ATPase
MM1218R_RS16180	COG1022	Amp-dependent synthetase and ligase
MM1218R_RS16210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MM1218R_RS16215	COG1845	cytochrome c oxidase, subunit III
MM1218R_RS16220	COG2010	Cytochrome c
MM1218R_RS16260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM1218R_RS16290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MM1218R_RS16295	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MM1218R_RS16310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MM1218R_RS16320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MM1218R_RS16385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS16580	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS16620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MM1218R_RS16620	COG0473	3-isopropylmalate dehydrogenase activity
MM1218R_RS16645	COG0321	lipoyl(octanoyl) transferase activity
MM1218R_RS16650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MM1218R_RS16685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MM1218R_RS16715	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MM1218R_RS16770	COG3323	Protein of unknown function (DUF1653)
MM1218R_RS16770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MM1218R_RS16795	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MM1218R_RS16810	COG0596	Alpha beta hydrolase
MM1218R_RS16835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM1218R_RS16850	COG0022	dehydrogenase e1 component
MM1218R_RS16880	COG1063	alcohol dehydrogenase
MM1218R_RS16930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM1218R_RS17010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MM1218R_RS17015	COG4221	oxidoreductase activity
MM1218R_RS17050	COG1231	oxidoreductase activity
MM1218R_RS17090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MM1218R_RS17100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MM1218R_RS17115	COG0720	synthase
MM1218R_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS17250	COG1309	transcriptional regulator
MM1218R_RS17260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS17340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM1218R_RS17340	COG0493	'glutamate synthase
MM1218R_RS17345	COG1013	pyruvate-flavodoxin oxidoreductase activity
MM1218R_RS17345	COG0674	pyruvate-flavodoxin oxidoreductase activity
MM1218R_RS17345	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MM1218R_RS17345	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MM1218R_RS17355	COG0574	Belongs to the PEP-utilizing enzyme family
MM1218R_RS17355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MM1218R_RS17360	COG0205	6-phosphofructokinase activity
MM1218R_RS17385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MM1218R_RS17405	COG0493	'glutamate synthase
MM1218R_RS17410	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MM1218R_RS17425	COG0657	acetylesterase activity
MM1218R_RS17445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MM1218R_RS17450	COG0657	acetylesterase activity
MM1218R_RS17500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS17610	COG1218	3'(2'),5'-bisphosphate nucleotidase
MM1218R_RS17625	COG0277	FAD linked oxidase domain protein
MM1218R_RS17685	COG0596	Alpha beta hydrolase
MM1218R_RS17690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MM1218R_RS17765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MM1218R_RS17770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM1218R_RS17775	COG0022	dehydrogenase e1 component
MM1218R_RS17785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM1218R_RS17895	COG1024	Enoyl-CoA hydratase
MM1218R_RS17900	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS17925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MM1218R_RS17950	COG0326	Molecular chaperone. Has ATPase activity
MM1218R_RS17965	COG2814	Major facilitator Superfamily
MM1218R_RS17970	COG2226	methyltransferase
MM1218R_RS17990	COG1063	alcohol dehydrogenase
MM1218R_RS18015	COG2226	methyltransferase
MM1218R_RS18020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS18030	COG0384	phenazine biosynthesis protein PhzF
MM1218R_RS18080	COG5651	PPE family
MM1218R_RS18115	COG1376	ErfK ybiS ycfS ynhG family protein
MM1218R_RS18145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MM1218R_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS18260	COG4842	Belongs to the WXG100 family
MM1218R_RS18425	COG1175	transmembrane transport
MM1218R_RS18445	COG0531	amino acid
MM1218R_RS18450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MM1218R_RS18455	COG1834	amidinotransferase
MM1218R_RS18460	COG1522	sequence-specific DNA binding
MM1218R_RS18480	COG1716	ATPase activity
MM1218R_RS18480	COG0842	Transport permease protein
MM1218R_RS18480	COG1131	(ABC) transporter
MM1218R_RS18515	COG0475	glutathione-regulated potassium exporter activity
MM1218R_RS18520	COG2226	methyltransferase
MM1218R_RS18525	COG2223	nitrite transmembrane transporter activity
MM1218R_RS18535	COG0243	molybdopterin cofactor binding
MM1218R_RS18580	COG1045	serine acetyltransferase
MM1218R_RS18610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MM1218R_RS18715	COG1381	Involved in DNA repair and RecF pathway recombination
MM1218R_RS18740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MM1218R_RS18770	COG0484	heat shock protein binding
MM1218R_RS18775	COG1420	regulation of RNA biosynthetic process
MM1218R_RS18790	COG1595	DNA-templated transcription, initiation
MM1218R_RS18800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS18800	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MM1218R_RS18810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS18825	COG3321	synthase
MM1218R_RS18825	COG0604	alcohol dehydrogenase
MM1218R_RS18845	COG1021	2,3-dihydroxybenzoate-AMP ligase
MM1218R_RS18850	COG0657	acetylesterase activity
MM1218R_RS18865	COG2072	flavoprotein involved in K transport
MM1218R_RS18930	COG1297	OPT oligopeptide transporter protein
MM1218R_RS18940	COG4208	sulfate ABC transporter
MM1218R_RS18945	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MM1218R_RS18950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MM1218R_RS18960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM1218R_RS18965	COG3387	PFAM Glycoside hydrolase 15-related
MM1218R_RS18990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM1218R_RS18990	COG0617	tRNA 3'-terminal CCA addition
MM1218R_RS18990	COG0517	IMP dehydrogenase activity
MM1218R_RS18995	COG1234	tRNA 3'-trailer cleavage
MM1218R_RS19010	COG1305	Transglutaminase-like
MM1218R_RS19025	COG0268	Binds directly to 16S ribosomal RNA
MM1218R_RS19040	COG1596	polysaccharide export
MM1218R_RS19040	COG1555	photosystem II stabilization
MM1218R_RS19045	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19050	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19090	COG2755	lipolytic protein G-D-S-L family
MM1218R_RS19100	COG0799	negative regulation of ribosome biogenesis
MM1218R_RS19105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MM1218R_RS19120	COG0542	response to heat
MM1218R_RS19125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MM1218R_RS19130	COG0668	transmembrane transport
MM1218R_RS19135	COG0840	transmembrane signaling receptor activity
MM1218R_RS19140	COG0668	transmembrane transport
MM1218R_RS19145	COG5002	protein histidine kinase activity
MM1218R_RS19185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MM1218R_RS19190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MM1218R_RS19195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MM1218R_RS19200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MM1218R_RS19205	COG1530	ribonuclease E activity
MM1218R_RS19210	COG0105	UTP biosynthetic process
MM1218R_RS19220	COG0285	dihydrofolate synthase activity
MM1218R_RS19240	COG3268	Saccharopine dehydrogenase
MM1218R_RS19245	COG1388	LysM domain
MM1218R_RS19245	COG1388	LysM domain
MM1218R_RS19260	COG3321	synthase
MM1218R_RS19260	COG0604	alcohol dehydrogenase
MM1218R_RS19265	COG3321	synthase
MM1218R_RS19265	COG0604	alcohol dehydrogenase
MM1218R_RS19285	COG3321	synthase
MM1218R_RS19285	COG0604	alcohol dehydrogenase
MM1218R_RS19290	COG3321	synthase
MM1218R_RS19290	COG0604	alcohol dehydrogenase
MM1218R_RS19305	COG0604	alcohol dehydrogenase
MM1218R_RS19305	COG3321	synthase
MM1218R_RS19305	COG0604	alcohol dehydrogenase
MM1218R_RS19305	COG3321	synthase
MM1218R_RS19310	COG0746	molybdenum cofactor guanylyltransferase activity
MM1218R_RS19315	COG1013	pyruvate-flavodoxin oxidoreductase activity
MM1218R_RS19320	COG0674	pyruvate-flavodoxin oxidoreductase activity
MM1218R_RS19320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MM1218R_RS19330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MM1218R_RS19340	COG0740	serine-type endopeptidase activity
MM1218R_RS19350	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM1218R_RS19365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS19385	COG1301	dicarboxylic acid transport
MM1218R_RS19390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM1218R_RS19425	COG0366	Alpha amylase catalytic
MM1218R_RS19460	COG2902	Dehydrogenase
MM1218R_RS19475	COG0629	single-stranded DNA binding
MM1218R_RS19490	COG2937	Belongs to the GPAT DAPAT family
MM1218R_RS19505	COG0657	acetylesterase activity
MM1218R_RS19520	COG1492	cobalamin metabolic process
MM1218R_RS19540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS19545	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM1218R_RS19565	COG2030	dehydratase
MM1218R_RS19570	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM1218R_RS19595	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS19620	COG0300	oxidoreductase activity
MM1218R_RS19625	COG0433	COG0433 Predicted ATPase
MM1218R_RS19630	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MM1218R_RS19645	COG1309	transcriptional regulator
MM1218R_RS19655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS19700	COG1376	ErfK ybiS ycfS ynhG family protein
MM1218R_RS19760	COG0736	holo-[acyl-carrier-protein] synthase activity
MM1218R_RS19775	COG3757	hydrolase, family 25
MM1218R_RS19780	COG4638	Rieske (2fe-2S)
MM1218R_RS19855	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19860	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19865	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19870	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19915	COG2172	sigma factor antagonist activity
MM1218R_RS19915	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS19915	COG2208	phosphoserine phosphatase activity
MM1218R_RS19920	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19925	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS19945	COG2124	cytochrome p450
MM1218R_RS19965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM1218R_RS19980	COG4221	oxidoreductase activity
MM1218R_RS20010	COG2124	cytochrome p450
MM1218R_RS20025	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS20045	COG1024	Enoyl-CoA hydratase
MM1218R_RS20080	COG1024	Enoyl-CoA hydratase
MM1218R_RS20085	COG1024	Enoyl-CoA hydratase
MM1218R_RS20090	COG1024	Enoyl-CoA hydratase
MM1218R_RS20115	COG1802	Transcriptional regulator
MM1218R_RS20120	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS20125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS20130	COG0183	Belongs to the thiolase family
MM1218R_RS20140	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS20160	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM1218R_RS20185	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MM1218R_RS20205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MM1218R_RS20210	COG1522	sequence-specific DNA binding
MM1218R_RS20225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS20230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS20255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MM1218R_RS20270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MM1218R_RS20315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MM1218R_RS20320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MM1218R_RS20330	COG0058	SHG alpha-glucan phosphorylase activity
MM1218R_RS20340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MM1218R_RS20355	COG0346	lactoylglutathione lyase activity
MM1218R_RS20365	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MM1218R_RS20435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM1218R_RS20450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MM1218R_RS20455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MM1218R_RS20460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MM1218R_RS20465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MM1218R_RS20470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM1218R_RS20470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MM1218R_RS20475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MM1218R_RS20480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM1218R_RS20485	COG0356	it plays a direct role in the translocation of protons across the membrane
MM1218R_RS20505	COG2890	protein-(glutamine-N5) methyltransferase activity
MM1218R_RS20510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MM1218R_RS20515	COG0254	rRNA binding
MM1218R_RS20530	COG0083	homoserine kinase activity
MM1218R_RS20540	COG0460	homoserine dehydrogenase
MM1218R_RS20550	COG0018	arginyl-trna synthetase
MM1218R_RS20585	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS20585	COG1454	alcohol dehydrogenase
MM1218R_RS20600	COG0596	Alpha beta hydrolase
MM1218R_RS20615	COG3391	amine dehydrogenase activity
MM1218R_RS20620	COG0583	DNA-binding transcription factor activity
MM1218R_RS20630	COG3548	integral membrane protein
MM1218R_RS20670	COG3391	amine dehydrogenase activity
MM1218R_RS20830	COG0583	DNA-binding transcription factor activity
MM1218R_RS20835	COG2301	Belongs to the HpcH HpaI aldolase family
MM1218R_RS20845	COG0427	acetyl-CoA hydrolase
MM1218R_RS20895	COG0842	Transport permease protein
MM1218R_RS20895	COG1131	(ABC) transporter
MM1218R_RS20895	COG1716	ATPase activity
MM1218R_RS20945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS20965	COG0277	FAD linked oxidase domain protein
MM1218R_RS20985	COG0657	acetylesterase activity
MM1218R_RS21025	COG0508	dehydrogenase complex catalyzes the overall conversion of
MM1218R_RS21025	COG0567	Dehydrogenase, E1 component
MM1218R_RS21045	COG0039	L-malate dehydrogenase activity
MM1218R_RS21050	COG0598	Magnesium transport protein CorA
MM1218R_RS21060	COG1113	amino acid transport
MM1218R_RS21100	COG2239	Acts as a magnesium transporter
MM1218R_RS21120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MM1218R_RS21125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM1218R_RS21130	COG5662	AntiSigma factor
MM1218R_RS21140	COG4122	O-methyltransferase activity
MM1218R_RS21150	COG1309	transcriptional regulator
MM1218R_RS21155	COG1131	(ABC) transporter
MM1218R_RS21160	COG3559	Exporter of polyketide antibiotics
MM1218R_RS21175	COG0657	acetylesterase activity
MM1218R_RS21180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MM1218R_RS21195	COG0519	Catalyzes the synthesis of GMP from XMP
MM1218R_RS21205	COG0463	Glycosyl transferase, family 2
MM1218R_RS21215	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS21220	COG1611	Belongs to the LOG family
MM1218R_RS21245	COG0477	Major facilitator Superfamily
MM1218R_RS21255	COG5651	PPE family
MM1218R_RS21260	COG0657	acetylesterase activity
MM1218R_RS21270	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS21275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MM1218R_RS21275	COG0596	Alpha beta hydrolase
MM1218R_RS21275	COG2226	methyltransferase
MM1218R_RS21285	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS21315	COG0506	proline dehydrogenase activity
MM1218R_RS21320	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS21325	COG3835	regulator
MM1218R_RS21330	COG4424	Sulfotransferase
MM1218R_RS21350	COG0529	Catalyzes the synthesis of activated sulfate
MM1218R_RS21365	COG0475	glutathione-regulated potassium exporter activity
MM1218R_RS21370	COG2046	Belongs to the sulfate adenylyltransferase family
MM1218R_RS21380	COG2223	nitrite transmembrane transporter activity
MM1218R_RS21405	COG0657	acetylesterase activity
MM1218R_RS21415	COG1061	Type III restriction enzyme res subunit
MM1218R_RS21425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MM1218R_RS21430	COG1695	Transcriptional regulator
MM1218R_RS21435	COG1902	pentaerythritol trinitrate reductase activity
MM1218R_RS21435	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM1218R_RS21445	COG3979	chitinase
MM1218R_RS21465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MM1218R_RS21490	COG1217	gtp-binding protein TYPA
MM1218R_RS21535	COG3467	pyridoxamine 5'-phosphate
MM1218R_RS21545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS21570	COG2409	Drug exporters of the RND superfamily
MM1218R_RS21590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS21595	COG1024	Enoyl-CoA hydratase
MM1218R_RS21600	COG0702	epimerase
MM1218R_RS21610	COG0702	epimerase
MM1218R_RS21620	COG1755	Isoprenylcysteine carboxyl methyltransferase
MM1218R_RS21635	COG1024	Enoyl-CoA hydratase
MM1218R_RS21640	COG0183	Belongs to the thiolase family
MM1218R_RS21665	COG1012	belongs to the aldehyde dehydrogenase family
MM1218R_RS21670	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS21685	COG1309	transcriptional regulator
MM1218R_RS21690	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS21715	COG0574	Belongs to the PEP-utilizing enzyme family
MM1218R_RS21715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MM1218R_RS21730	COG0596	Alpha beta hydrolase
MM1218R_RS21735	COG1309	transcriptional regulator
MM1218R_RS21750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MM1218R_RS21825	COG0012	GTP binding
MM1218R_RS21835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MM1218R_RS21845	COG1570	exodeoxyribonuclease VII activity
MM1218R_RS21850	COG1722	exodeoxyribonuclease VII activity
MM1218R_RS21885	COG2272	Belongs to the type-B carboxylesterase lipase family
MM1218R_RS21930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MM1218R_RS21940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MM1218R_RS21945	COG0572	uridine kinase
MM1218R_RS21980	COG1331	Highly conserved protein containing a thioredoxin domain
MM1218R_RS22020	COG0657	acetylesterase activity
MM1218R_RS22025	COG2755	lipolytic protein G-D-S-L family
MM1218R_RS22030	COG0183	Belongs to the thiolase family
MM1218R_RS22040	COG1024	Enoyl-CoA hydratase
MM1218R_RS22055	COG3391	amine dehydrogenase activity
MM1218R_RS22100	COG0657	acetylesterase activity
MM1218R_RS22120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MM1218R_RS22130	COG3119	arylsulfatase activity
MM1218R_RS22140	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS22145	COG3391	amine dehydrogenase activity
MM1218R_RS22170	COG1309	transcriptional regulator
MM1218R_RS22195	COG1414	Transcriptional regulator
MM1218R_RS22290	COG2801	Transposase and inactivated derivatives
MM1218R_RS22330	COG0657	acetylesterase activity
MM1218R_RS22350	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS22355	COG2205	protein histidine kinase activity
MM1218R_RS22385	COG4948	Mandelate Racemase Muconate Lactonizing
MM1218R_RS22395	COG3956	TIGRFAM MazG family protein
MM1218R_RS22415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MM1218R_RS22425	COG1393	Belongs to the ArsC family
MM1218R_RS22445	COG0193	aminoacyl-tRNA hydrolase activity
MM1218R_RS22460	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS22470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MM1218R_RS22490	COG0084	hydrolase, TatD family'
MM1218R_RS22500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MM1218R_RS22510	COG1045	serine acetyltransferase
MM1218R_RS22550	COG2235	arginine
MM1218R_RS22570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MM1218R_RS22570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MM1218R_RS22575	COG2226	methyltransferase
MM1218R_RS22615	COG0438	transferase activity, transferring glycosyl groups
MM1218R_RS22660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MM1218R_RS22705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MM1218R_RS22710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MM1218R_RS22725	COG1970	mechanosensitive ion channel activity
MM1218R_RS22730	COG0521	Mo-molybdopterin cofactor biosynthetic process
MM1218R_RS22730	COG0315	cyclic pyranopterin monophosphate synthase activity
MM1218R_RS22735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM1218R_RS22740	COG2205	protein histidine kinase activity
MM1218R_RS22745	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS22760	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS22765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM1218R_RS22780	COG1024	Enoyl-CoA hydratase
MM1218R_RS22805	COG0138	bifunctional purine biosynthesis protein purh
MM1218R_RS22845	COG0045	succinate-CoA ligase (ADP-forming) activity
MM1218R_RS22850	COG0739	heme binding
MM1218R_RS22880	COG0166	Belongs to the GPI family
MM1218R_RS22890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MM1218R_RS22945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS22985	COG0581	inorganic phosphate transmembrane transporter activity
MM1218R_RS23030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS23050	COG0657	acetylesterase activity
MM1218R_RS23110	COG0657	acetylesterase activity
MM1218R_RS23195	COG0477	Major facilitator Superfamily
MM1218R_RS23200	COG0156	8-amino-7-oxononanoate synthase activity
MM1218R_RS23275	COG0259	pyridoxamine-phosphate oxidase activity
MM1218R_RS23305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MM1218R_RS23320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM1218R_RS23345	COG2814	Major facilitator Superfamily
MM1218R_RS23360	COG0435	Glutathione S-transferase
MM1218R_RS23370	COG1278	Cold shock
MM1218R_RS23375	COG3304	Inner membrane component domain
MM1218R_RS23380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MM1218R_RS23400	COG0521	Mo-molybdopterin cofactor biosynthetic process
MM1218R_RS23420	COG1061	Type III restriction enzyme res subunit
MM1218R_RS23450	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM1218R_RS23450	COG1024	Enoyl-CoA hydratase
MM1218R_RS23455	COG0183	Belongs to the thiolase family
MM1218R_RS23475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS23485	COG3961	Belongs to the TPP enzyme family
MM1218R_RS23510	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS23525	COG1024	Enoyl-CoA hydratase
MM1218R_RS23600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MM1218R_RS23625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS23630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS23640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS23650	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS23665	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS23685	COG0778	Nitroreductase
MM1218R_RS23685	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MM1218R_RS23725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MM1218R_RS23745	COG2124	cytochrome p450
MM1218R_RS23755	COG0657	acetylesterase activity
MM1218R_RS23775	COG1309	transcriptional regulator
MM1218R_RS23780	COG0183	Belongs to the thiolase family
MM1218R_RS23800	COG4638	Rieske (2fe-2S)
MM1218R_RS23810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM1218R_RS23820	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS23830	COG0659	secondary active sulfate transmembrane transporter activity
MM1218R_RS23835	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS23860	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS23865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS23875	COG0006	proline dipeptidase activity
MM1218R_RS23925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM1218R_RS23935	COG2132	Multicopper oxidase
MM1218R_RS23950	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS23960	COG1053	succinate dehydrogenase
MM1218R_RS23965	COG3384	dioxygenase
MM1218R_RS23970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM1218R_RS23985	COG1053	succinate dehydrogenase
MM1218R_RS23990	COG4585	Histidine kinase
MM1218R_RS24005	COG4585	Histidine kinase
MM1218R_RS24010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MM1218R_RS24035	COG0596	Alpha beta hydrolase
MM1218R_RS24045	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS24050	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS24065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MM1218R_RS24070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS24075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MM1218R_RS24080	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MM1218R_RS24080	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MM1218R_RS24120	COG0142	geranyltranstransferase activity
MM1218R_RS24155	COG1304	FMN binding
MM1218R_RS24190	COG4689	acetoacetate decarboxylase
MM1218R_RS24205	COG0657	acetylesterase activity
MM1218R_RS24210	COG1278	Cold shock
MM1218R_RS24225	COG1410	methionine synthase
MM1218R_RS24225	COG0646	methionine synthase
MM1218R_RS24295	COG1609	Transcriptional regulator
MM1218R_RS24320	COG4974	Belongs to the 'phage' integrase family
MM1218R_RS24350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS24355	COG0590	tRNA wobble adenosine to inosine editing
MM1218R_RS24360	COG0640	Transcriptional regulator
MM1218R_RS24400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM1218R_RS24420	COG0454	-acetyltransferase
MM1218R_RS24420	COG0456	acetyltransferase
MM1218R_RS24425	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS24455	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MM1218R_RS24470	COG1937	Protein conserved in bacteria
MM1218R_RS24500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MM1218R_RS24555	COG1362	aminopeptidase activity
MM1218R_RS24560	COG2837	iron assimilation
MM1218R_RS24590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MM1218R_RS24610	COG0583	DNA-binding transcription factor activity
MM1218R_RS24625	COG0477	Major facilitator Superfamily
MM1218R_RS24645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MM1218R_RS24680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MM1218R_RS24760	COG2124	cytochrome p450
MM1218R_RS24805	COG2205	protein histidine kinase activity
MM1218R_RS24810	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS24825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MM1218R_RS24830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MM1218R_RS24830	COG2080	2 iron, 2 sulfur cluster binding
MM1218R_RS24850	COG2233	PERMEase
MM1218R_RS24855	COG3119	arylsulfatase activity
MM1218R_RS24865	COG1024	Enoyl-CoA hydratase
MM1218R_RS24870	COG0406	alpha-ribazole phosphatase activity
MM1218R_RS24885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MM1218R_RS24940	COG1316	TRANSCRIPTIONal
MM1218R_RS24960	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS24965	COG0156	8-amino-7-oxononanoate synthase activity
MM1218R_RS24970	COG1024	Enoyl-CoA hydratase
MM1218R_RS24975	COG0390	transport system, permease component
MM1218R_RS24980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM1218R_RS24990	COG1695	Transcriptional regulator
MM1218R_RS25000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MM1218R_RS25025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MM1218R_RS25050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS25055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MM1218R_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS25070	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25075	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25080	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS25085	COG0657	acetylesterase activity
MM1218R_RS25095	COG0028	Belongs to the TPP enzyme family
MM1218R_RS25115	COG3001	Fructosamine kinase
MM1218R_RS25120	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS25125	COG1024	Enoyl-CoA hydratase
MM1218R_RS25130	COG2124	cytochrome p450
MM1218R_RS25140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MM1218R_RS25190	COG4638	Rieske (2fe-2S)
MM1218R_RS25205	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS25215	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MM1218R_RS25215	COG2308	Evidence 4 Homologs of previously reported genes of
MM1218R_RS25220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM1218R_RS25225	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MM1218R_RS25230	COG3971	2-oxopent-4-enoate hydratase activity
MM1218R_RS25235	COG1053	succinate dehydrogenase
MM1218R_RS25240	COG2030	dehydratase
MM1218R_RS25260	COG2030	dehydratase
MM1218R_RS25265	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25270	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25280	COG0183	Belongs to the thiolase family
MM1218R_RS25295	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS25300	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS25310	COG1024	Enoyl-CoA hydratase
MM1218R_RS25330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MM1218R_RS25340	COG0183	Belongs to the thiolase family
MM1218R_RS25360	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25365	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS25370	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25375	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25380	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25385	COG0436	Aminotransferase
MM1218R_RS25395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MM1218R_RS25455	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS25460	COG1309	transcriptional regulator
MM1218R_RS25465	COG1609	Transcriptional regulator
MM1218R_RS25475	COG1116	anion transmembrane transporter activity
MM1218R_RS25480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM1218R_RS25495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MM1218R_RS25505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MM1218R_RS25510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM1218R_RS25515	COG0215	cysteine-tRNA ligase activity
MM1218R_RS25520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MM1218R_RS25525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MM1218R_RS25565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM1218R_RS25570	COG3002	Belongs to the UPF0753 family
MM1218R_RS25620	COG0477	Major facilitator Superfamily
MM1218R_RS25665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MM1218R_RS25670	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MM1218R_RS25675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MM1218R_RS25705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MM1218R_RS25710	COG0302	gtp cyclohydrolase
MM1218R_RS25715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM1218R_RS25720	COG2267	carboxylic ester hydrolase activity
MM1218R_RS25730	COG1063	alcohol dehydrogenase
MM1218R_RS25740	COG0657	acetylesterase activity
MM1218R_RS25785	COG2027	D-alanyl-D-alanine carboxypeptidase
MM1218R_RS25790	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MM1218R_RS25835	COG0470	DNA polymerase III
MM1218R_RS25860	COG1205	dead DEAH box helicase
MM1218R_RS25860	COG1111	helicase
MM1218R_RS25925	COG4172	Belongs to the ABC transporter superfamily
MM1218R_RS25930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM1218R_RS25935	COG0601	transmembrane transport
MM1218R_RS25995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM1218R_RS26000	COG0251	oxidation-reduction process
MM1218R_RS26030	COG1408	metallophosphoesterase
MM1218R_RS26035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MM1218R_RS26065	COG3707	response regulator
MM1218R_RS26080	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS26085	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS26090	COG2172	sigma factor antagonist activity
MM1218R_RS26100	COG2208	phosphoserine phosphatase activity
MM1218R_RS26100	COG2172	sigma factor antagonist activity
MM1218R_RS26100	COG1366	Belongs to the anti-sigma-factor antagonist family
MM1218R_RS26110	COG0693	protein deglycase activity
MM1218R_RS26115	COG0709	Synthesizes selenophosphate from selenide and ATP
MM1218R_RS26130	COG3276	selenocysteine insertion sequence binding
MM1218R_RS26145	COG0243	molybdopterin cofactor binding
MM1218R_RS26145	COG3383	formate dehydrogenase (NAD+) activity
MM1218R_RS26150	COG0243	molybdopterin cofactor binding
MM1218R_RS26150	COG3383	formate dehydrogenase (NAD+) activity
MM1218R_RS26155	COG0437	4 iron, 4 sulfur cluster binding
MM1218R_RS26185	COG0714	Associated with various cellular activities
MM1218R_RS26210	COG3391	amine dehydrogenase activity
MM1218R_RS26215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MM1218R_RS26230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM1218R_RS26240	COG0121	glutamine amidotransferase
MM1218R_RS26245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MM1218R_RS26290	COG1132	(ABC) transporter
MM1218R_RS26300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MM1218R_RS26320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MM1218R_RS26330	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MM1218R_RS26340	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM1218R_RS26355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MM1218R_RS26370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM1218R_RS26485	COG1793	dna ligase
MM1218R_RS26495	COG2124	cytochrome p450
MM1218R_RS26530	COG1022	Amp-dependent synthetase and ligase
MM1218R_RS26545	COG2072	flavoprotein involved in K transport
MM1218R_RS26555	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS26560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM1218R_RS26590	COG1028	Short-chain dehydrogenase reductase Sdr
MM1218R_RS26610	COG0393	Putative heavy-metal-binding
MM1218R_RS26640	COG0287	Prephenate dehydrogenase
MM1218R_RS26655	COG1174	glycine betaine transport
MM1218R_RS26670	COG5416	Lipopolysaccharide assembly protein A domain
MM1218R_RS26710	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS26720	COG0604	alcohol dehydrogenase
MM1218R_RS26725	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MM1218R_RS26735	COG2205	protein histidine kinase activity
MM1218R_RS26740	COG0745	RESPONSE REGULATOR receiver
MM1218R_RS26755	COG3391	amine dehydrogenase activity
MM1218R_RS26765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM1218R_RS26790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MM1218R_RS26810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MM1218R_RS26815	COG5651	PPE family
MM1218R_RS26875	COG0346	lactoylglutathione lyase activity
MM1218R_RS26880	COG0640	Transcriptional regulator
MM1218R_RS26895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MM1218R_RS26910	COG2268	Band 7 protein
MM1218R_RS26970	COG1960	acyl-CoA dehydrogenase activity
MM1218R_RS26975	COG0657	acetylesterase activity
MM1218R_RS26980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MM1218R_RS26985	COG3321	synthase
MM1218R_RS26985	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MM1218R_RS26985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MM1218R_RS26990	COG0318	PFAM AMP-dependent synthetase and ligase
MM1218R_RS27000	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MM1218R_RS27015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MM1218R_RS27030	COG1216	Glycosyl transferase, family 2
MM1218R_RS27050	COG0561	phosphatase activity
MM1218R_RS27100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MM1218R_RS27115	COG0588	phosphoglycerate mutase activity
MM1218R_RS27120	COG0077	Prephenate dehydratase
MM1218R_RS27130	COG1316	TRANSCRIPTIONal
MM1218R_RS27160	COG2119	membrane
MM1218R_RS27200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM1218R_RS27205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MM1218R_RS27205	COG1796	DNA polymerase
MM1218R_RS27240	COG0069	glutamate synthase activity
MM1218R_RS27240	COG0067	glutamate synthase
MM1218R_RS27240	COG0070	glutamate synthase
MM1218R_RS27485	COG1404	Belongs to the peptidase S8 family
MM1218R_RS27580	COG1595	DNA-templated transcription, initiation
MM1218R_RS27600	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM1218R_RS27600	COG3409	Peptidoglycan-binding domain 1 protein
MM1218R_RS27615	COG1192	Involved in chromosome partitioning
MM1218R_RS27620	COG0357	Ribosomal RNA small subunit methyltransferase G
MM1218R_RS27630	COG0706	membrane insertase activity
MM1218R_RS27635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MM1218R_RS27640	COG0594	ribonuclease P activity
MM1218R_RS27645	COG0230	Belongs to the bacterial ribosomal protein bL34 family