locus-tag	class	description
G6N15_RS00080	COG0640	Transcriptional regulator
G6N15_RS00105	COG2259	Doxx family
G6N15_RS00110	COG1695	Transcriptional regulator
G6N15_RS00145	COG1175	transmembrane transport
G6N15_RS00150	COG0395	ABC-type sugar transport system, permease component
G6N15_RS00175	COG1716	ATPase activity
G6N15_RS00175	COG1131	(ABC) transporter
G6N15_RS00175	COG0842	Transport permease protein
G6N15_RS00220	COG2032	superoxide dismutase activity
G6N15_RS00265	COG1381	Involved in DNA repair and RecF pathway recombination
G6N15_RS00275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6N15_RS00310	COG0484	heat shock protein binding
G6N15_RS00315	COG1420	regulation of RNA biosynthetic process
G6N15_RS00325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N15_RS00330	COG1595	DNA-templated transcription, initiation
G6N15_RS00355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N15_RS00375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N15_RS00380	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6N15_RS00390	COG0657	acetylesterase activity
G6N15_RS00405	COG2072	flavoprotein involved in K transport
G6N15_RS00415	COG1169	isochorismate synthase
G6N15_RS00480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6N15_RS00485	COG4208	sulfate ABC transporter
G6N15_RS00495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6N15_RS00530	COG0516	GMP reductase activity
G6N15_RS00530	COG0517	IMP dehydrogenase activity
G6N15_RS00545	COG1305	Transglutaminase-like
G6N15_RS00555	COG2308	Evidence 4 Homologs of previously reported genes of
G6N15_RS00560	COG0268	Binds directly to 16S ribosomal RNA
G6N15_RS00575	COG1596	polysaccharide export
G6N15_RS00575	COG1555	photosystem II stabilization
G6N15_RS00590	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS00595	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS00635	COG0799	negative regulation of ribosome biogenesis
G6N15_RS00650	COG0542	response to heat
G6N15_RS00655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6N15_RS00670	COG1132	(ABC) transporter
G6N15_RS00675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6N15_RS00695	COG5002	protein histidine kinase activity
G6N15_RS00700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N15_RS00720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6N15_RS00720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6N15_RS00750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G6N15_RS00760	COG1530	ribonuclease E activity
G6N15_RS00775	COG0285	dihydrofolate synthase activity
G6N15_RS00795	COG3268	Saccharopine dehydrogenase
G6N15_RS00800	COG0823	Involved in the tonB-independent uptake of proteins
G6N15_RS00800	COG1506	peptidase
G6N15_RS00810	COG1388	LysM domain
G6N15_RS00820	COG1013	pyruvate-flavodoxin oxidoreductase activity
G6N15_RS00825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G6N15_RS00825	COG0674	pyruvate-flavodoxin oxidoreductase activity
G6N15_RS00835	COG2040	homocysteine
G6N15_RS00840	COG0740	serine-type endopeptidase activity
G6N15_RS00890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N15_RS00920	COG0366	Alpha amylase catalytic
G6N15_RS00940	COG3467	pyridoxamine 5'-phosphate
G6N15_RS00990	COG2902	Dehydrogenase
G6N15_RS01000	COG0629	single-stranded DNA binding
G6N15_RS01010	COG2937	Belongs to the GPAT DAPAT family
G6N15_RS01040	COG2032	superoxide dismutase activity
G6N15_RS01050	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N15_RS01070	COG2030	dehydratase
G6N15_RS01075	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N15_RS01105	COG0300	oxidoreductase activity
G6N15_RS01110	COG0433	COG0433 Predicted ATPase
G6N15_RS01115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G6N15_RS01130	COG1376	ErfK ybiS ycfS ynhG family protein
G6N15_RS01145	COG2267	carboxylic ester hydrolase activity
G6N15_RS01160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6N15_RS01175	COG3757	hydrolase, family 25
G6N15_RS01230	COG2124	cytochrome p450
G6N15_RS01270	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01275	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01280	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01285	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01310	COG1053	succinate dehydrogenase
G6N15_RS01320	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS01325	COG1024	Enoyl-CoA hydratase
G6N15_RS01335	COG0022	dehydrogenase e1 component
G6N15_RS01340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6N15_RS01355	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01360	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01370	COG2124	cytochrome p450
G6N15_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS01395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N15_RS01425	COG2124	cytochrome p450
G6N15_RS01435	COG0183	Belongs to the thiolase family
G6N15_RS01440	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01465	COG1024	Enoyl-CoA hydratase
G6N15_RS01470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N15_RS01475	COG0300	oxidoreductase activity
G6N15_RS01485	COG1024	Enoyl-CoA hydratase
G6N15_RS01500	COG1024	Enoyl-CoA hydratase
G6N15_RS01505	COG1024	Enoyl-CoA hydratase
G6N15_RS01510	COG1024	Enoyl-CoA hydratase
G6N15_RS01530	COG1802	Transcriptional regulator
G6N15_RS01535	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS01545	COG0183	Belongs to the thiolase family
G6N15_RS01555	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS01590	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6N15_RS01610	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6N15_RS01615	COG1234	tRNA 3'-trailer cleavage
G6N15_RS01620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6N15_RS01660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6N15_RS01705	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N15_RS01720	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N15_RS01740	COG1716	ATPase activity
G6N15_RS01740	COG0842	Transport permease protein
G6N15_RS01740	COG1131	(ABC) transporter
G6N15_RS01790	COG0058	SHG alpha-glucan phosphorylase activity
G6N15_RS01800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6N15_RS01815	COG0346	lactoylglutathione lyase activity
G6N15_RS01825	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G6N15_RS01860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6N15_RS01895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N15_RS01895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6N15_RS01905	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6N15_RS01930	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N15_RS01945	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS01965	COG0460	homoserine dehydrogenase
G6N15_RS01970	COG0019	diaminopimelate decarboxylase activity
G6N15_RS01975	COG0018	arginyl-trna synthetase
G6N15_RS01995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N15_RS02045	COG1218	3'(2'),5'-bisphosphate nucleotidase
G6N15_RS02090	COG1309	transcriptional regulator
G6N15_RS02115	COG0604	alcohol dehydrogenase
G6N15_RS02130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N15_RS02135	COG0066	3-isopropylmalate dehydratase activity
G6N15_RS02235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS02250	COG0277	FAD linked oxidase domain protein
G6N15_RS02305	COG1695	Transcriptional regulator
G6N15_RS02315	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6N15_RS02315	COG0567	Dehydrogenase, E1 component
G6N15_RS02340	COG0598	Magnesium transport protein CorA
G6N15_RS02385	COG2239	Acts as a magnesium transporter
G6N15_RS02410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS02415	COG5662	AntiSigma factor
G6N15_RS02430	COG1309	transcriptional regulator
G6N15_RS02435	COG1131	(ABC) transporter
G6N15_RS02440	COG3559	Exporter of polyketide antibiotics
G6N15_RS02455	COG0297	glycogen (starch) synthase activity
G6N15_RS02465	COG0519	Catalyzes the synthesis of GMP from XMP
G6N15_RS02475	COG0463	Glycosyl transferase, family 2
G6N15_RS02490	COG1611	Belongs to the LOG family
G6N15_RS02515	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS02525	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS02535	COG0506	proline dehydrogenase activity
G6N15_RS02540	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS02565	COG0531	amino acid
G6N15_RS02570	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS02580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N15_RS02605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N15_RS02635	COG1140	nitrate reductase beta subunit
G6N15_RS02695	COG3467	pyridoxamine 5'-phosphate
G6N15_RS02710	COG2188	Transcriptional regulator
G6N15_RS02735	COG2409	Drug exporters of the RND superfamily
G6N15_RS02750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6N15_RS02765	COG0604	alcohol dehydrogenase
G6N15_RS02765	COG3321	synthase
G6N15_RS02775	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS02780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS02795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS02800	COG1024	Enoyl-CoA hydratase
G6N15_RS02810	COG0702	epimerase
G6N15_RS02820	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6N15_RS02830	COG1024	Enoyl-CoA hydratase
G6N15_RS02835	COG0183	Belongs to the thiolase family
G6N15_RS02895	COG1733	regulation of RNA biosynthetic process
G6N15_RS02905	COG0574	Belongs to the PEP-utilizing enzyme family
G6N15_RS02905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N15_RS02945	COG1309	transcriptional regulator
G6N15_RS02960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6N15_RS02980	COG1487	ribonuclease activity
G6N15_RS03000	COG0012	GTP binding
G6N15_RS03025	COG1570	exodeoxyribonuclease VII activity
G6N15_RS03050	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS03085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G6N15_RS03100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6N15_RS03110	COG0572	uridine kinase
G6N15_RS03145	COG1331	Highly conserved protein containing a thioredoxin domain
G6N15_RS03190	COG0657	acetylesterase activity
G6N15_RS03195	COG2755	lipolytic protein G-D-S-L family
G6N15_RS03200	COG0183	Belongs to the thiolase family
G6N15_RS03210	COG1024	Enoyl-CoA hydratase
G6N15_RS03255	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS03305	COG0531	amino acid
G6N15_RS03310	COG0531	amino acid
G6N15_RS03340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6N15_RS03345	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6N15_RS03400	COG3956	TIGRFAM MazG family protein
G6N15_RS03415	COG1309	transcriptional regulator
G6N15_RS03435	COG1393	Belongs to the ArsC family
G6N15_RS03455	COG0193	aminoacyl-tRNA hydrolase activity
G6N15_RS03460	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS03480	COG0084	hydrolase, TatD family'
G6N15_RS03530	COG2132	Multicopper oxidase
G6N15_RS03545	COG1595	DNA-templated transcription, initiation
G6N15_RS03590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6N15_RS03590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6N15_RS03595	COG2226	methyltransferase
G6N15_RS03770	COG4974	Belongs to the 'phage' integrase family
G6N15_RS03795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6N15_RS03800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6N15_RS03815	COG1970	mechanosensitive ion channel activity
G6N15_RS03820	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N15_RS03820	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N15_RS03825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS03855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N15_RS03870	COG1024	Enoyl-CoA hydratase
G6N15_RS03890	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
G6N15_RS03895	COG0138	bifunctional purine biosynthesis protein purh
G6N15_RS03930	COG0045	succinate-CoA ligase (ADP-forming) activity
G6N15_RS03935	COG0739	heme binding
G6N15_RS03960	COG0166	Belongs to the GPI family
G6N15_RS03970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N15_RS03975	COG1950	PFAM Membrane protein of
G6N15_RS03985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6N15_RS04000	COG2201	protein-glutamate methylesterase activity
G6N15_RS04055	COG0246	Mannitol dehydrogenase
G6N15_RS04080	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N15_RS04085	COG1366	Belongs to the anti-sigma-factor antagonist family
G6N15_RS04090	COG2172	sigma factor antagonist activity
G6N15_RS04125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS04175	COG1403	HNH endonuclease
G6N15_RS04200	COG1309	transcriptional regulator
G6N15_RS04250	COG0259	pyridoxamine-phosphate oxidase activity
G6N15_RS04275	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G6N15_RS04315	COG2814	Major facilitator Superfamily
G6N15_RS04325	COG0435	Glutathione S-transferase
G6N15_RS04335	COG1278	Cold shock
G6N15_RS04345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6N15_RS04365	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6N15_RS04365	COG0315	cyclic pyranopterin monophosphate synthase activity
G6N15_RS04385	COG1061	Type III restriction enzyme res subunit
G6N15_RS04400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS04415	COG2813	Specifically methylates the guanine in position
G6N15_RS04425	COG0183	Belongs to the thiolase family
G6N15_RS04445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS04470	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS04480	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS04485	COG1024	Enoyl-CoA hydratase
G6N15_RS04530	COG1309	transcriptional regulator
G6N15_RS04600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N15_RS04625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS04630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS04635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS04645	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04670	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS04680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N15_RS04715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6N15_RS04745	COG2124	cytochrome p450
G6N15_RS04770	COG1141	Ferredoxin
G6N15_RS04795	COG0183	Belongs to the thiolase family
G6N15_RS04800	COG1024	Enoyl-CoA hydratase
G6N15_RS04805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04830	COG4638	Rieske (2fe-2S)
G6N15_RS04840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N15_RS04850	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS04855	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS04860	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS04990	COG3384	dioxygenase
G6N15_RS04995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS05000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6N15_RS05020	COG1845	cytochrome c oxidase, subunit III
G6N15_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS05050	COG1309	transcriptional regulator
G6N15_RS05060	COG0183	Belongs to the thiolase family
G6N15_RS05075	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS05080	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS05100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS05110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N15_RS05115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N15_RS05115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G6N15_RS05165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS05175	COG0640	Transcriptional regulator
G6N15_RS05210	COG1316	TRANSCRIPTIONal
G6N15_RS05220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N15_RS05225	COG0581	inorganic phosphate transmembrane transporter activity
G6N15_RS05245	COG0745	RESPONSE REGULATOR receiver
G6N15_RS05255	COG3118	belongs to the thioredoxin family
G6N15_RS05295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6N15_RS05345	COG2837	iron assimilation
G6N15_RS05375	COG0753	catalase activity
G6N15_RS05405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6N15_RS05415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6N15_RS05430	COG0386	Belongs to the glutathione peroxidase family
G6N15_RS05435	COG0477	Major facilitator Superfamily
G6N15_RS05480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N15_RS05500	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS05515	COG0028	Belongs to the TPP enzyme family
G6N15_RS05535	COG2124	cytochrome p450
G6N15_RS05600	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N15_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS05625	COG2205	protein histidine kinase activity
G6N15_RS05630	COG0745	RESPONSE REGULATOR receiver
G6N15_RS05695	COG1316	TRANSCRIPTIONal
G6N15_RS05710	COG2072	flavoprotein involved in K transport
G6N15_RS05720	COG0346	lactoylglutathione lyase activity
G6N15_RS05735	COG1053	succinate dehydrogenase
G6N15_RS05750	COG2084	Dehydrogenase
G6N15_RS05760	COG1024	Enoyl-CoA hydratase
G6N15_RS05770	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6N15_RS05800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS05830	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS05835	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS05895	COG4638	Rieske (2fe-2S)
G6N15_RS05910	COG0028	Belongs to the TPP enzyme family
G6N15_RS05925	COG1024	Enoyl-CoA hydratase
G6N15_RS05940	COG2124	cytochrome p450
G6N15_RS05950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS05965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6N15_RS05985	COG4638	Rieske (2fe-2S)
G6N15_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS06015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N15_RS06020	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6N15_RS06025	COG3971	2-oxopent-4-enoate hydratase activity
G6N15_RS06035	COG2030	dehydratase
G6N15_RS06055	COG2030	dehydratase
G6N15_RS06060	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06065	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06075	COG0183	Belongs to the thiolase family
G6N15_RS06095	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS06105	COG1024	Enoyl-CoA hydratase
G6N15_RS06125	COG0183	Belongs to the thiolase family
G6N15_RS06135	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS06140	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06145	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS06150	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06155	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06160	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06165	COG0436	Aminotransferase
G6N15_RS06215	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS06220	COG1309	transcriptional regulator
G6N15_RS06225	COG1609	Transcriptional regulator
G6N15_RS06235	COG1120	ATPase activity
G6N15_RS06240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6N15_RS06280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6N15_RS06285	COG1329	Transcriptional regulator
G6N15_RS06310	COG2409	Drug exporters of the RND superfamily
G6N15_RS06310	COG1033	growth of symbiont in host cell
G6N15_RS06340	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N15_RS06370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6N15_RS06400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6N15_RS06410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N15_RS06415	COG2267	carboxylic ester hydrolase activity
G6N15_RS06425	COG1063	alcohol dehydrogenase
G6N15_RS06440	COG1113	amino acid transport
G6N15_RS06470	COG2027	D-alanyl-D-alanine carboxypeptidase
G6N15_RS06500	COG1215	transferase activity, transferring glycosyl groups
G6N15_RS06535	COG0470	DNA polymerase III
G6N15_RS06565	COG1278	Cold shock
G6N15_RS06570	COG1111	helicase
G6N15_RS06570	COG1205	dead DEAH box helicase
G6N15_RS06710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6N15_RS06715	COG0601	transmembrane transport
G6N15_RS06725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N15_RS06760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G6N15_RS06775	COG3547	Transposase (IS116 IS110 IS902 family)
G6N15_RS06780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N15_RS06815	COG1408	metallophosphoesterase
G6N15_RS06820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6N15_RS06830	COG0028	Belongs to the TPP enzyme family
G6N15_RS06860	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N15_RS06865	COG0693	protein deglycase activity
G6N15_RS06880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS06905	COG0714	Associated with various cellular activities
G6N15_RS06940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6N15_RS06960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6N15_RS06975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N15_RS06995	COG1764	response to oxidative stress
G6N15_RS07045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6N15_RS07065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G6N15_RS07070	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N15_RS07085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS07095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6N15_RS07115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N15_RS07205	COG2124	cytochrome p450
G6N15_RS07220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N15_RS07230	COG1793	dna ligase
G6N15_RS07245	COG0798	PFAM Bile acid sodium symporter
G6N15_RS07250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6N15_RS07280	COG0596	Alpha beta hydrolase
G6N15_RS07320	COG0287	Prephenate dehydrogenase
G6N15_RS07335	COG1174	glycine betaine transport
G6N15_RS07350	COG5416	Lipopolysaccharide assembly protein A domain
G6N15_RS07360	COG0406	alpha-ribazole phosphatase activity
G6N15_RS07415	COG2205	protein histidine kinase activity
G6N15_RS07420	COG0745	RESPONSE REGULATOR receiver
G6N15_RS07550	COG3609	addiction module antidote protein, CC2985 family
G6N15_RS07555	COG2337	Toxic component of a toxin-antitoxin (TA) module
G6N15_RS07580	COG0277	FAD linked oxidase domain protein
G6N15_RS07645	COG2826	transposase and inactivated derivatives, IS30 family
G6N15_RS07660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N15_RS07690	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6N15_RS07705	COG1216	Glycosyl transferase, family 2
G6N15_RS07725	COG0561	phosphatase activity
G6N15_RS07755	COG2755	lipolytic protein G-D-S-L family
G6N15_RS07755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N15_RS07780	COG0667	Aldo Keto reductase
G6N15_RS07820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6N15_RS07845	COG2890	protein-(glutamine-N5) methyltransferase activity
G6N15_RS07915	COG2226	methyltransferase
G6N15_RS07960	COG3251	PFAM MbtH domain protein
G6N15_RS07980	COG3321	synthase
G6N15_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS07980	COG0604	alcohol dehydrogenase
G6N15_RS07985	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS08055	COG1316	TRANSCRIPTIONal
G6N15_RS08090	COG2119	membrane
G6N15_RS08125	COG2072	flavoprotein involved in K transport
G6N15_RS08135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6N15_RS08150	COG1796	DNA polymerase
G6N15_RS08150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G6N15_RS08160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS08175	COG0070	glutamate synthase
G6N15_RS08175	COG0069	glutamate synthase activity
G6N15_RS08175	COG0067	glutamate synthase
G6N15_RS08195	COG0464	growth
G6N15_RS08205	COG1404	Belongs to the peptidase S8 family
G6N15_RS08270	COG1674	ftsk spoiiie
G6N15_RS08330	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS08345	COG1716	ATPase activity
G6N15_RS08370	COG0515	serine threonine protein kinase
G6N15_RS08415	COG0758	DNA mediated transformation
G6N15_RS08420	COG1040	competence protein
G6N15_RS08450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6N15_RS08450	COG1372	Participates in initiation and elongation during chromosome replication
G6N15_RS08460	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G6N15_RS08470	COG0592	DNA-directed DNA polymerase activity
G6N15_RS08475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6N15_RS08490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6N15_RS08495	COG0706	membrane insertase activity
G6N15_RS08505	COG0357	Ribosomal RNA small subunit methyltransferase G
G6N15_RS08510	COG1192	Involved in chromosome partitioning
G6N15_RS08525	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N15_RS08525	COG3409	Peptidoglycan-binding domain 1 protein
G6N15_RS08605	COG4221	oxidoreductase activity
G6N15_RS08615	COG1126	abc transporter atp-binding protein
G6N15_RS08620	COG0765	amino acid transport
G6N15_RS08655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS08665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6N15_RS08675	COG0360	Binds together with S18 to 16S ribosomal RNA
G6N15_RS08685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6N15_RS08700	COG0481	GTPase activity
G6N15_RS08700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G6N15_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS08725	COG4689	acetoacetate decarboxylase
G6N15_RS08745	COG2030	dehydratase
G6N15_RS08760	COG4638	Rieske (2fe-2S)
G6N15_RS08765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N15_RS08780	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G6N15_RS08815	COG2226	methyltransferase
G6N15_RS08835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6N15_RS08840	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS08850	COG1024	Enoyl-CoA hydratase
G6N15_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS08870	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS08880	COG3386	PFAM SMP-30 Gluconolaconase
G6N15_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS08895	COG2072	flavoprotein involved in K transport
G6N15_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS08905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS08910	COG0028	Belongs to the TPP enzyme family
G6N15_RS08920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N15_RS08920	COG2755	lipolytic protein G-D-S-L family
G6N15_RS08935	COG1376	ErfK ybiS ycfS ynhG family protein
G6N15_RS08970	COG0330	HflC and HflK could
G6N15_RS08985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS09010	COG0842	Transport permease protein
G6N15_RS09010	COG1129	ABC transporter
G6N15_RS09120	COG0477	Major facilitator Superfamily
G6N15_RS09125	COG1733	regulation of RNA biosynthetic process
G6N15_RS09130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N15_RS09160	COG0783	Belongs to the Dps family
G6N15_RS09165	COG1741	Belongs to the pirin family
G6N15_RS09180	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS09185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS09190	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS09205	COG2365	Tyrosine phosphatase family
G6N15_RS09210	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS09235	COG1309	transcriptional regulator
G6N15_RS09240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS09255	COG0277	FAD linked oxidase domain protein
G6N15_RS09305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6N15_RS09320	COG1802	Transcriptional regulator
G6N15_RS09330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS09335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS09360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N15_RS09375	COG1714	RDD family
G6N15_RS09400	COG0626	cystathionine gamma-synthase activity
G6N15_RS09450	COG2267	carboxylic ester hydrolase activity
G6N15_RS09465	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N15_RS09470	COG4122	O-methyltransferase activity
G6N15_RS09495	COG1937	Protein conserved in bacteria
G6N15_RS09500	COG2814	Major facilitator Superfamily
G6N15_RS09505	COG1376	ErfK ybiS ycfS ynhG family protein
G6N15_RS09510	COG3590	peptidase
G6N15_RS09525	COG1832	CoA-binding protein
G6N15_RS09555	COG2409	Drug exporters of the RND superfamily
G6N15_RS09580	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G6N15_RS09595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G6N15_RS09605	COG1024	Enoyl-CoA hydratase
G6N15_RS09640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N15_RS09645	COG2124	cytochrome p450
G6N15_RS09675	COG0367	asparagine synthase
G6N15_RS09680	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N15_RS09680	COG2308	Evidence 4 Homologs of previously reported genes of
G6N15_RS09700	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS09710	COG1024	Enoyl-CoA hydratase
G6N15_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS09780	COG0438	transferase activity, transferring glycosyl groups
G6N15_RS09820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6N15_RS09845	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS09880	COG0783	Belongs to the Dps family
G6N15_RS09905	COG4981	capsule polysaccharide biosynthetic process
G6N15_RS09915	COG1472	Belongs to the glycosyl hydrolase 3 family
G6N15_RS09925	COG2030	dehydratase
G6N15_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS09935	COG0183	Belongs to the thiolase family
G6N15_RS09940	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS09955	COG1053	succinate dehydrogenase
G6N15_RS09970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N15_RS09970	COG2146	nitrite reductase [NAD(P)H] activity
G6N15_RS09975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N15_RS09975	COG2146	nitrite reductase [NAD(P)H] activity
G6N15_RS09990	COG2223	nitrite transmembrane transporter activity
G6N15_RS10005	COG1984	allophanate hydrolase subunit 2
G6N15_RS10010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6N15_RS10020	COG1309	transcriptional regulator
G6N15_RS10030	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS10035	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS10050	COG0346	lactoylglutathione lyase activity
G6N15_RS10065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS10075	COG1609	Transcriptional regulator
G6N15_RS10085	COG0464	growth
G6N15_RS10130	COG1404	Belongs to the peptidase S8 family
G6N15_RS10145	COG1309	transcriptional regulator
G6N15_RS10170	COG4424	Sulfotransferase
G6N15_RS10185	COG1368	sulfuric ester hydrolase activity
G6N15_RS10195	COG0778	Nitroreductase
G6N15_RS10245	COG1716	ATPase activity
G6N15_RS10245	COG0842	Transport permease protein
G6N15_RS10245	COG1131	(ABC) transporter
G6N15_RS10320	COG0784	Response regulator, receiver
G6N15_RS10325	COG4251	negative regulation of phosphorylation
G6N15_RS10330	COG0745	RESPONSE REGULATOR receiver
G6N15_RS10340	COG3550	peptidyl-serine autophosphorylation
G6N15_RS10360	COG3328	transposase activity
G6N15_RS10365	COG1376	ErfK ybiS ycfS ynhG family protein
G6N15_RS10395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N15_RS10430	COG0247	lactate metabolic process
G6N15_RS10430	COG2181	nitrate reductase activity
G6N15_RS10435	COG0443	Heat shock 70 kDa protein
G6N15_RS10455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS10525	COG0443	Heat shock 70 kDa protein
G6N15_RS10530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6N15_RS10535	COG0484	heat shock protein binding
G6N15_RS10540	COG0789	Transcriptional regulator
G6N15_RS10560	COG0640	Transcriptional regulator
G6N15_RS10575	COG0542	response to heat
G6N15_RS10600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6N15_RS10640	COG1994	Peptidase M50
G6N15_RS10680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G6N15_RS10695	COG1252	NADH dehydrogenase
G6N15_RS10705	COG4221	oxidoreductase activity
G6N15_RS10740	COG3546	catalase activity
G6N15_RS10750	COG1937	Protein conserved in bacteria
G6N15_RS10780	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS10785	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS10800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS10810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS10825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N15_RS10865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6N15_RS10890	COG2104	thiamine diphosphate biosynthetic process
G6N15_RS10925	COG2234	aminopeptidase activity
G6N15_RS10930	COG2234	aminopeptidase activity
G6N15_RS10935	COG1403	HNH endonuclease
G6N15_RS10965	COG2072	flavoprotein involved in K transport
G6N15_RS10970	COG0789	Transcriptional regulator
G6N15_RS10995	COG3707	response regulator
G6N15_RS11035	COG0242	peptide deformylase activity
G6N15_RS11050	COG2032	superoxide dismutase activity
G6N15_RS11070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N15_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS11105	COG1061	Type III restriction enzyme res subunit
G6N15_RS11135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N15_RS11135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N15_RS11150	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS11175	COG1505	serine-type exopeptidase activity
G6N15_RS11180	COG2226	methyltransferase
G6N15_RS11235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS11265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS11275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS11295	COG2733	membrane
G6N15_RS11320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G6N15_RS11380	COG5002	protein histidine kinase activity
G6N15_RS11390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS11395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6N15_RS11420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G6N15_RS11450	COG1082	Xylose isomerase domain protein TIM barrel
G6N15_RS11485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS11490	COG2030	dehydratase
G6N15_RS11495	COG0560	Phosphoserine phosphatase
G6N15_RS11510	COG0181	hydroxymethylbilane synthase activity
G6N15_RS11515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N15_RS11540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6N15_RS11540	COG2755	lipolytic protein G-D-S-L family
G6N15_RS11560	COG1113	amino acid transport
G6N15_RS11580	COG0406	alpha-ribazole phosphatase activity
G6N15_RS11590	COG0785	Cytochrome C biogenesis protein
G6N15_RS11600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6N15_RS11630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6N15_RS11690	COG4221	oxidoreductase activity
G6N15_RS11710	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS11720	COG4948	Mandelate Racemase Muconate Lactonizing
G6N15_RS11725	COG4977	sequence-specific DNA binding
G6N15_RS11780	COG0501	Belongs to the peptidase M48B family
G6N15_RS11785	COG0387	Pfam Sodium calcium exchanger
G6N15_RS11805	COG2072	flavoprotein involved in K transport
G6N15_RS11840	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6N15_RS11845	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6N15_RS11850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G6N15_RS11950	COG3012	SEC-C Motif Domain Protein
G6N15_RS11955	COG0653	protein targeting
G6N15_RS11970	COG3537	Alpha-1,2-mannosidase
G6N15_RS12030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N15_RS12035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6N15_RS12095	COG5522	Integral membrane protein (intg_mem_TP0381)
G6N15_RS12125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N15_RS12170	COG4221	oxidoreductase activity
G6N15_RS12185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6N15_RS12205	COG0778	Nitroreductase
G6N15_RS12220	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6N15_RS12230	COG0243	molybdopterin cofactor binding
G6N15_RS12245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6N15_RS12270	COG2030	dehydratase
G6N15_RS12275	COG2030	dehydratase
G6N15_RS12290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6N15_RS12305	COG0081	regulation of translation
G6N15_RS12310	COG4941	Belongs to the sigma-70 factor family
G6N15_RS12320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS12325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6N15_RS12340	COG2318	DinB family
G6N15_RS12400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6N15_RS12415	COG3328	transposase activity
G6N15_RS12440	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS12455	COG1024	Enoyl-CoA hydratase
G6N15_RS12475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6N15_RS12525	COG0535	radical SAM domain protein
G6N15_RS12605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6N15_RS12645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6N15_RS12675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6N15_RS12685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6N15_RS12690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6N15_RS12700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6N15_RS12715	COG0200	Binds to the 23S rRNA
G6N15_RS12725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS12730	COG0616	signal peptide processing
G6N15_RS12750	COG2826	transposase and inactivated derivatives, IS30 family
G6N15_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS12760	COG1063	alcohol dehydrogenase
G6N15_RS12770	COG1917	Cupin 2, conserved barrel domain protein
G6N15_RS12770	COG2207	Transcriptional regulator
G6N15_RS12780	COG0235	Class ii aldolase
G6N15_RS12785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N15_RS12800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS12805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS12845	COG2072	flavoprotein involved in K transport
G6N15_RS12850	COG0028	Belongs to the TPP enzyme family
G6N15_RS12865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6N15_RS12900	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS12920	COG3794	PFAM blue (type 1) copper domain protein
G6N15_RS12935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS12945	COG0577	efflux transmembrane transporter activity
G6N15_RS12945	COG1136	(ABC) transporter
G6N15_RS12950	COG1136	(ABC) transporter
G6N15_RS12950	COG0577	efflux transmembrane transporter activity
G6N15_RS12990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6N15_RS12995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6N15_RS13005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6N15_RS13045	COG1404	Belongs to the peptidase S8 family
G6N15_RS13055	COG1674	ftsk spoiiie
G6N15_RS13065	COG4842	Belongs to the WXG100 family
G6N15_RS13070	COG4842	Belongs to the WXG100 family
G6N15_RS13105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS13130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6N15_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS13155	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS13165	COG0076	glutamate decarboxylase activity
G6N15_RS13185	COG1214	PFAM Peptidase M22, glycoprotease
G6N15_RS13185	COG0456	acetyltransferase
G6N15_RS13190	COG0456	acetyltransferase
G6N15_RS13205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6N15_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS13270	COG0516	GMP reductase activity
G6N15_RS13300	COG0519	Catalyzes the synthesis of GMP from XMP
G6N15_RS13300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6N15_RS13325	COG4221	oxidoreductase activity
G6N15_RS13330	COG0406	alpha-ribazole phosphatase activity
G6N15_RS13335	COG2030	dehydratase
G6N15_RS13345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6N15_RS13350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6N15_RS13350	COG0561	phosphatase activity
G6N15_RS13365	COG0587	DNA-directed DNA polymerase activity
G6N15_RS13375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6N15_RS13380	COG5002	protein histidine kinase activity
G6N15_RS13385	COG2018	Roadblock/LC7 domain
G6N15_RS13400	COG0842	Transport permease protein
G6N15_RS13400	COG1716	ATPase activity
G6N15_RS13400	COG1131	(ABC) transporter
G6N15_RS13405	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6N15_RS13405	COG1902	pentaerythritol trinitrate reductase activity
G6N15_RS13410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6N15_RS13435	COG2409	Drug exporters of the RND superfamily
G6N15_RS13435	COG1033	growth of symbiont in host cell
G6N15_RS13450	COG0277	FAD linked oxidase domain protein
G6N15_RS13455	COG2826	transposase and inactivated derivatives, IS30 family
G6N15_RS13475	COG2873	o-acetylhomoserine
G6N15_RS13500	COG1295	ribonuclease BN
G6N15_RS13505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6N15_RS13510	COG2814	Major facilitator Superfamily
G6N15_RS13515	COG1686	Belongs to the peptidase S11 family
G6N15_RS13520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N15_RS13525	COG1595	DNA-templated transcription, initiation
G6N15_RS13555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6N15_RS13560	COG1053	succinate dehydrogenase
G6N15_RS13570	COG2009	succinate dehydrogenase
G6N15_RS13600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6N15_RS13605	COG0390	transport system, permease component
G6N15_RS13610	COG2304	oxidoreductase activity
G6N15_RS13615	COG2304	oxidoreductase activity
G6N15_RS13625	COG3511	phospholipase C
G6N15_RS13630	COG3511	phospholipase C
G6N15_RS13640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N15_RS13655	COG1473	amidohydrolase
G6N15_RS13655	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N15_RS13680	COG0564	pseudouridine synthase activity
G6N15_RS13685	COG2313	pseudouridylate synthase activity
G6N15_RS13710	COG1201	RNA secondary structure unwinding
G6N15_RS13720	COG1309	transcriptional regulator
G6N15_RS13725	COG1309	transcriptional regulator
G6N15_RS13740	COG2271	Major facilitator Superfamily
G6N15_RS13755	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS13765	COG1522	sequence-specific DNA binding
G6N15_RS13820	COG4770	biotin carboxylase activity
G6N15_RS13850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6N15_RS13855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G6N15_RS13855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G6N15_RS13875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6N15_RS13885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS13890	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS13930	COG1316	TRANSCRIPTIONal
G6N15_RS13955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6N15_RS13970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G6N15_RS13990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6N15_RS14010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS14015	COG0531	amino acid
G6N15_RS14020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6N15_RS14040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6N15_RS14060	COG5401	PFAM Sporulation and spore germination
G6N15_RS14090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6N15_RS14095	COG0653	protein targeting
G6N15_RS14120	COG2326	polyphosphate kinase activity
G6N15_RS14140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N15_RS14145	COG1162	GTPase activity
G6N15_RS14150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6N15_RS14155	COG2135	peptidase activity
G6N15_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS14170	COG5662	AntiSigma factor
G6N15_RS14180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6N15_RS14195	COG1597	lipid kinase activity
G6N15_RS14215	COG0406	alpha-ribazole phosphatase activity
G6N15_RS14280	COG0596	Alpha beta hydrolase
G6N15_RS14295	COG0789	Transcriptional regulator
G6N15_RS14350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6N15_RS14365	COG3480	Lon protease (S16) C-terminal proteolytic domain
G6N15_RS14395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G6N15_RS14395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G6N15_RS14410	COG0604	alcohol dehydrogenase
G6N15_RS14460	COG0714	Associated with various cellular activities
G6N15_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS14495	COG1309	transcriptional regulator
G6N15_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS14520	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS14525	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS14535	COG0714	Associated with various cellular activities
G6N15_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS14560	COG2124	cytochrome p450
G6N15_RS14565	COG1024	Enoyl-CoA hydratase
G6N15_RS14595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N15_RS14605	COG1034	ATP synthesis coupled electron transport
G6N15_RS14630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6N15_RS14660	COG0301	tRNA thio-modification
G6N15_RS14675	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS14685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6N15_RS14690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS14715	COG0604	alcohol dehydrogenase
G6N15_RS14720	COG0667	Aldo Keto reductase
G6N15_RS14735	COG0402	S-adenosylhomocysteine deaminase activity
G6N15_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS14805	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS14810	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS14820	COG0483	inositol monophosphate 1-phosphatase activity
G6N15_RS14845	COG0668	transmembrane transport
G6N15_RS14855	COG2884	Cell division ATP-binding protein ftsE
G6N15_RS14900	COG1024	Enoyl-CoA hydratase
G6N15_RS14910	COG0515	serine threonine protein kinase
G6N15_RS14910	COG2815	serine threonine protein kinase
G6N15_RS14920	COG2301	Belongs to the HpcH HpaI aldolase family
G6N15_RS14945	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6N15_RS15045	COG0688	phosphatidylethanolamine metabolic process
G6N15_RS15060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6N15_RS15070	COG1966	Carbon starvation protein
G6N15_RS15085	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS15115	COG0375	protein maturation
G6N15_RS15175	COG1309	transcriptional regulator
G6N15_RS15205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6N15_RS15215	COG1119	ATPase activity
G6N15_RS15245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6N15_RS15250	COG0110	maltose O-acetyltransferase activity
G6N15_RS15260	COG1304	FMN binding
G6N15_RS15300	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G6N15_RS15305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6N15_RS15360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G6N15_RS15405	COG0205	6-phosphofructokinase activity
G6N15_RS15420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6N15_RS15470	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G6N15_RS15480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G6N15_RS15485	COG0309	Hydrogenase expression formation protein (HypE)
G6N15_RS15490	COG0298	carbon dioxide binding
G6N15_RS15495	COG0409	Hydrogenase expression formation protein
G6N15_RS15515	COG2259	Doxx family
G6N15_RS15545	COG0473	3-isopropylmalate dehydrogenase activity
G6N15_RS15565	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6N15_RS15570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6N15_RS15595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N15_RS15615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6N15_RS15625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G6N15_RS15630	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6N15_RS15650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6N15_RS15660	COG1461	Dihydroxyacetone kinase
G6N15_RS15680	COG0656	L-ascorbic acid biosynthetic process
G6N15_RS15700	COG0742	ribosomal rna small subunit methyltransferase
G6N15_RS15710	COG0701	Predicted permease
G6N15_RS15725	COG0571	ribonuclease III activity
G6N15_RS15735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6N15_RS15765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G6N15_RS15775	COG0657	acetylesterase activity
G6N15_RS15785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6N15_RS15810	COG2172	sigma factor antagonist activity
G6N15_RS15820	COG1686	Belongs to the peptidase S11 family
G6N15_RS15830	COG3547	Transposase (IS116 IS110 IS902 family)
G6N15_RS15835	COG0228	four-way junction DNA binding
G6N15_RS15845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6N15_RS15875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6N15_RS15935	COG0052	Belongs to the universal ribosomal protein uS2 family
G6N15_RS15945	COG0154	amidase activity
G6N15_RS15955	COG0546	phosphoglycolate phosphatase activity
G6N15_RS15990	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS16010	COG3707	response regulator
G6N15_RS16020	COG0723	plastoquinol--plastocyanin reductase activity
G6N15_RS16030	COG0438	transferase activity, transferring glycosyl groups
G6N15_RS16040	COG1088	dTDP-glucose 4,6-dehydratase activity
G6N15_RS16045	COG2192	nodulation
G6N15_RS16055	COG0859	PFAM glycosyl transferase family 9
G6N15_RS16060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G6N15_RS16065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G6N15_RS16065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G6N15_RS16080	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6N15_RS16085	COG0528	UMP kinase activity
G6N15_RS16090	COG0233	cytoplasmic translational termination
G6N15_RS16095	COG0575	Belongs to the CDS family
G6N15_RS16100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6N15_RS16120	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6N15_RS16155	COG1492	cobalamin metabolic process
G6N15_RS16165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6N15_RS16180	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6N15_RS16190	COG0735	belongs to the Fur family
G6N15_RS16220	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G6N15_RS16230	COG1022	Amp-dependent synthetase and ligase
G6N15_RS16230	COG3320	Male sterility
G6N15_RS16235	COG1648	precorrin-2 dehydrogenase activity
G6N15_RS16235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6N15_RS16285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G6N15_RS16335	COG2409	Drug exporters of the RND superfamily
G6N15_RS16350	COG0657	acetylesterase activity
G6N15_RS16420	COG1846	Transcriptional regulator
G6N15_RS16435	COG1846	Transcriptional regulator
G6N15_RS16445	COG1024	Enoyl-CoA hydratase
G6N15_RS16450	COG4118	positive regulation of growth
G6N15_RS16455	COG3744	PilT protein domain protein
G6N15_RS16490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G6N15_RS16495	COG0183	Belongs to the thiolase family
G6N15_RS16520	COG1185	polyribonucleotide nucleotidyltransferase activity
G6N15_RS16535	COG0686	Belongs to the AlaDH PNT family
G6N15_RS16540	COG1522	sequence-specific DNA binding
G6N15_RS16575	COG1403	HNH endonuclease
G6N15_RS16580	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6N15_RS16595	COG4770	biotin carboxylase activity
G6N15_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS16615	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS16620	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS16625	COG0667	Aldo Keto reductase
G6N15_RS16640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6N15_RS16655	COG3214	Protein conserved in bacteria
G6N15_RS16680	COG0745	RESPONSE REGULATOR receiver
G6N15_RS16685	COG2205	protein histidine kinase activity
G6N15_RS16690	COG0493	'glutamate synthase
G6N15_RS16690	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G6N15_RS16715	COG0142	geranyltranstransferase activity
G6N15_RS16725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N15_RS16735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G6N15_RS16770	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS16790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G6N15_RS16820	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
G6N15_RS16845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6N15_RS16855	COG1196	nuclear chromosome segregation
G6N15_RS16860	COG0697	spore germination
G6N15_RS16870	COG0697	spore germination
G6N15_RS16880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6N15_RS16890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6N15_RS16900	COG1960	acyl-CoA dehydrogenase activity
G6N15_RS16910	COG5479	isomerase activity
G6N15_RS16910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6N15_RS16920	COG1388	LysM domain
G6N15_RS16930	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G6N15_RS17040	COG0483	inositol monophosphate 1-phosphatase activity
G6N15_RS17090	COG0569	domain protein
G6N15_RS17095	COG0531	amino acid
G6N15_RS17165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6N15_RS17170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6N15_RS17185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N15_RS17185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6N15_RS17205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6N15_RS17210	COG1595	DNA-templated transcription, initiation
G6N15_RS17345	COG4948	Mandelate Racemase Muconate Lactonizing
G6N15_RS17360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6N15_RS17380	COG1376	ErfK ybiS ycfS ynhG family protein
G6N15_RS17395	COG1573	uracil-dna glycosylase
G6N15_RS17400	COG0028	Belongs to the TPP enzyme family
G6N15_RS17405	COG0277	FAD linked oxidase domain protein
G6N15_RS17405	COG0247	lactate metabolic process
G6N15_RS17410	COG1403	HNH endonuclease
G6N15_RS17415	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS17420	COG0640	Transcriptional regulator
G6N15_RS17460	COG0235	Class ii aldolase
G6N15_RS17480	COG4638	Rieske (2fe-2S)
G6N15_RS17500	COG3485	protocatechuate 3,4-dioxygenase
G6N15_RS17510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6N15_RS17525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6N15_RS17535	COG0330	HflC and HflK could
G6N15_RS17620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS17665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6N15_RS17675	COG1937	Protein conserved in bacteria
G6N15_RS17690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6N15_RS17770	COG0574	Belongs to the PEP-utilizing enzyme family
G6N15_RS17770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6N15_RS17805	COG2070	2-Nitropropane dioxygenase
G6N15_RS17850	COG0667	Aldo Keto reductase
G6N15_RS17880	COG0438	transferase activity, transferring glycosyl groups
G6N15_RS17885	COG1051	belongs to the nudix hydrolase family
G6N15_RS17895	COG1946	Acyl-CoA thioesterase
G6N15_RS17915	COG0632	four-way junction helicase activity
G6N15_RS17930	COG3320	Male sterility
G6N15_RS17930	COG1022	Amp-dependent synthetase and ligase
G6N15_RS17945	COG0778	Nitroreductase
G6N15_RS17965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6N15_RS17970	COG0747	negative chemotaxis
G6N15_RS17980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6N15_RS18000	COG0124	histidyl-tRNA synthetase
G6N15_RS18015	COG0235	Class ii aldolase
G6N15_RS18020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6N15_RS18130	COG0432	Pfam Uncharacterised protein family UPF0047
G6N15_RS18145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6N15_RS18150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6N15_RS18190	COG0006	proline dipeptidase activity
G6N15_RS18210	COG1982	Orn Lys Arg decarboxylase major
G6N15_RS18245	COG0540	Belongs to the ATCase OTCase family
G6N15_RS18260	COG0505	Belongs to the CarA family
G6N15_RS18270	COG0284	orotidine-5'-phosphate decarboxylase activity
G6N15_RS18275	COG3585	molybdate ion transport
G6N15_RS18280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6N15_RS18290	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G6N15_RS18305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6N15_RS18350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6N15_RS18415	COG0322	excinuclease ABC activity
G6N15_RS18420	COG1660	Displays ATPase and GTPase activities
G6N15_RS18455	COG0126	phosphoglycerate kinase activity
G6N15_RS18460	COG0149	triose-phosphate isomerase activity
G6N15_RS18470	COG1309	transcriptional regulator
G6N15_RS18505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6N15_RS18520	COG5651	PPE family
G6N15_RS18550	COG1131	(ABC) transporter
G6N15_RS18575	COG0396	ATPase activity
G6N15_RS18585	COG0822	iron-sulfur transferase activity
G6N15_RS18605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G6N15_RS18640	COG0640	Transcriptional regulator
G6N15_RS18645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6N15_RS18655	COG0488	(ABC) transporter
G6N15_RS18665	COG1309	transcriptional regulator
G6N15_RS18670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6N15_RS18680	COG0791	NLP P60 protein
G6N15_RS18680	COG3883	PFAM NLP P60 protein
G6N15_RS18690	COG0714	Associated with various cellular activities
G6N15_RS18700	COG2304	oxidoreductase activity
G6N15_RS18750	COG0745	RESPONSE REGULATOR receiver
G6N15_RS18755	COG2205	protein histidine kinase activity
G6N15_RS18810	COG2070	2-Nitropropane dioxygenase
G6N15_RS18815	COG1309	transcriptional regulator
G6N15_RS18840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6N15_RS18850	COG2226	methyltransferase
G6N15_RS18860	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS18870	COG5651	PPE family
G6N15_RS18875	COG2409	Drug exporters of the RND superfamily
G6N15_RS18895	COG0252	asparaginase activity
G6N15_RS18925	COG0300	oxidoreductase activity
G6N15_RS18930	COG2161	toxin-antitoxin pair type II binding
G6N15_RS18935	COG4115	mRNA cleavage
G6N15_RS19005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6N15_RS19010	COG0156	8-amino-7-oxononanoate synthase activity
G6N15_RS19075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6N15_RS19105	COG0131	Imidazoleglycerol-phosphate dehydratase
G6N15_RS19115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6N15_RS19120	COG0483	inositol monophosphate 1-phosphatase activity
G6N15_RS19125	COG0107	imidazoleglycerol-phosphate synthase activity
G6N15_RS19130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6N15_RS19135	COG2223	nitrite transmembrane transporter activity
G6N15_RS19140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6N15_RS19145	COG0493	'glutamate synthase
G6N15_RS19165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6N15_RS19215	COG1946	Acyl-CoA thioesterase
G6N15_RS19230	COG1132	(ABC) transporter
G6N15_RS19235	COG4988	ABC transporter
G6N15_RS19240	COG1294	oxidase, subunit
G6N15_RS19245	COG1271	oxidase subunit
G6N15_RS19310	COG0237	dephospho-CoA kinase activity
G6N15_RS19310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6N15_RS19320	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6N15_RS19325	COG1793	dna ligase
G6N15_RS19325	COG3285	dna ligase
G6N15_RS19340	COG1716	ATPase activity
G6N15_RS19340	COG1131	(ABC) transporter
G6N15_RS19340	COG0842	Transport permease protein
G6N15_RS19375	COG0443	Heat shock 70 kDa protein
G6N15_RS19425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6N15_RS19450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6N15_RS19455	COG0072	phenylalanine-tRNA ligase activity
G6N15_RS19455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N15_RS19465	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6N15_RS19480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6N15_RS19500	COG0488	(ABC) transporter
G6N15_RS19510	COG2835	tetraacyldisaccharide 4'-kinase activity
G6N15_RS19525	COG1131	(ABC) transporter
G6N15_RS19530	COG2094	Belongs to the DNA glycosylase MPG family
G6N15_RS19560	COG0647	UMP catabolic process
G6N15_RS19615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6N15_RS19620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6N15_RS19635	COG1160	GTP binding
G6N15_RS19695	COG0531	amino acid
G6N15_RS19700	COG0438	transferase activity, transferring glycosyl groups
G6N15_RS19735	COG1982	Orn Lys Arg decarboxylase major
G6N15_RS19745	COG1309	transcriptional regulator
G6N15_RS19800	COG1819	glycosyl
G6N15_RS19820	COG2223	nitrite transmembrane transporter activity
G6N15_RS19855	COG5651	PPE family
G6N15_RS19880	COG5651	PPE family
G6N15_RS19920	COG1404	Belongs to the peptidase S8 family
G6N15_RS19980	COG2239	Acts as a magnesium transporter
G6N15_RS19985	COG1914	H( )-stimulated, divalent metal cation uptake system
G6N15_RS19995	COG0531	amino acid
G6N15_RS20020	COG2801	Transposase and inactivated derivatives
G6N15_RS20050	COG0657	acetylesterase activity
G6N15_RS20075	COG2223	nitrite transmembrane transporter activity
G6N15_RS20105	COG1141	Ferredoxin
G6N15_RS20230	COG1253	flavin adenine dinucleotide binding
G6N15_RS20235	COG1253	flavin adenine dinucleotide binding
G6N15_RS20245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6N15_RS20270	COG1252	NADH dehydrogenase
G6N15_RS20275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS20410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6N15_RS20420	COG0583	DNA-binding transcription factor activity
G6N15_RS20435	COG1024	Enoyl-CoA hydratase
G6N15_RS20485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6N15_RS20520	COG1716	ATPase activity
G6N15_RS20545	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS20555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS20590	COG0243	molybdopterin cofactor binding
G6N15_RS20595	COG2070	2-Nitropropane dioxygenase
G6N15_RS20610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS20670	COG2814	Major facilitator Superfamily
G6N15_RS20720	COG1716	ATPase activity
G6N15_RS20775	COG0318	PFAM AMP-dependent synthetase and ligase
G6N15_RS20785	COG2124	cytochrome p450
G6N15_RS20800	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G6N15_RS20815	COG2755	lipolytic protein G-D-S-L family
G6N15_RS20835	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS20850	COG2130	NADP-dependent
G6N15_RS20880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6N15_RS20885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6N15_RS20900	COG2326	polyphosphate kinase activity
G6N15_RS20950	COG1024	Enoyl-CoA hydratase
G6N15_RS21050	COG2813	Specifically methylates the guanine in position
G6N15_RS21105	COG2002	toxin-antitoxin pair type II binding
G6N15_RS21115	COG1309	transcriptional regulator
G6N15_RS21135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6N15_RS21165	COG3842	ATPase activity
G6N15_RS21170	COG0395	ABC-type sugar transport system, permease component
G6N15_RS21175	COG1175	transmembrane transport
G6N15_RS21185	COG1595	DNA-templated transcription, initiation
G6N15_RS21195	COG1335	isochorismatase
G6N15_RS21205	COG0438	transferase activity, transferring glycosyl groups
G6N15_RS21210	COG2226	methyltransferase
G6N15_RS21245	COG3265	gluconokinase activity
G6N15_RS21255	COG2272	Belongs to the type-B carboxylesterase lipase family
G6N15_RS21270	COG0604	alcohol dehydrogenase
G6N15_RS21270	COG3321	synthase
G6N15_RS21295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6N15_RS21330	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G6N15_RS21335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G6N15_RS21340	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G6N15_RS21340	COG0235	Class ii aldolase
G6N15_RS21370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS21390	COG0300	oxidoreductase activity
G6N15_RS21445	COG2378	regulation of single-species biofilm formation
G6N15_RS21480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G6N15_RS21550	COG0477	Major facilitator Superfamily
G6N15_RS21555	COG1410	methionine synthase
G6N15_RS21555	COG0646	methionine synthase
G6N15_RS21565	COG4221	oxidoreductase activity
G6N15_RS21600	COG1968	undecaprenyl-diphosphatase activity
G6N15_RS21620	COG0167	dihydroorotate dehydrogenase activity
G6N15_RS21640	COG4221	oxidoreductase activity
G6N15_RS21670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G6N15_RS21680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6N15_RS21695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6N15_RS21750	COG0768	penicillin binding
G6N15_RS21810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6N15_RS21840	COG0003	Pfam Anion-transporting ATPase
G6N15_RS21890	COG1845	cytochrome c oxidase, subunit III
G6N15_RS21950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6N15_RS22025	COG2409	Drug exporters of the RND superfamily
G6N15_RS22065	COG0321	lipoyl(octanoyl) transferase activity
G6N15_RS22070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6N15_RS22100	COG2259	Doxx family
G6N15_RS22110	COG1295	ribonuclease BN
G6N15_RS22115	COG2020	methyltransferase activity
G6N15_RS22120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G6N15_RS22130	COG1403	HNH endonuclease
G6N15_RS22135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6N15_RS22170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6N15_RS22215	COG1012	belongs to the aldehyde dehydrogenase family
G6N15_RS22225	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G6N15_RS22240	COG1487	ribonuclease activity
G6N15_RS22250	COG3654	unkown
G6N15_RS22310	COG0596	Alpha beta hydrolase
G6N15_RS22355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6N15_RS22375	COG3547	Transposase (IS116 IS110 IS902 family)
G6N15_RS22385	COG0583	DNA-binding transcription factor activity
G6N15_RS22395	COG2226	methyltransferase
G6N15_RS22405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6N15_RS22455	COG4221	oxidoreductase activity
G6N15_RS22525	COG2124	cytochrome p450
G6N15_RS22535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G6N15_RS22540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6N15_RS22545	COG1028	Short-chain dehydrogenase reductase Sdr
G6N15_RS22560	COG4221	oxidoreductase activity
G6N15_RS22630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
