locus-tag	class	description
JN214_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN214_RS00010	COG0592	DNA-directed DNA polymerase activity
JN214_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JN214_RS00025	COG0187	DNA topoisomerase II activity
JN214_RS00065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JN214_RS00095	COG0515	serine threonine protein kinase
JN214_RS00120	COG1716	ATPase activity
JN214_RS00180	COG1960	acyl-CoA dehydrogenase activity
JN214_RS00260	COG0495	leucyl-tRNA aminoacylation
JN214_RS00275	COG1126	abc transporter atp-binding protein
JN214_RS00280	COG0765	amino acid transport
JN214_RS00290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS00305	COG1309	transcriptional regulator
JN214_RS00310	COG0596	Alpha beta hydrolase
JN214_RS00310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN214_RS00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN214_RS00370	COG0360	Binds together with S18 to 16S ribosomal RNA
JN214_RS00430	COG4584	PFAM Integrase catalytic
JN214_RS00480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN214_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS00520	COG2301	Belongs to the HpcH HpaI aldolase family
JN214_RS00535	COG1309	transcriptional regulator
JN214_RS00545	COG0494	nUDIX hydrolase
JN214_RS00560	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN214_RS00565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN214_RS00570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS00575	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JN214_RS00655	COG1309	transcriptional regulator
JN214_RS00670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS00675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS00745	COG1024	Enoyl-CoA hydratase
JN214_RS00750	COG1024	Enoyl-CoA hydratase
JN214_RS00755	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS00775	COG0183	Belongs to the thiolase family
JN214_RS00785	COG0183	Belongs to the thiolase family
JN214_RS00800	COG1233	COG1233 Phytoene dehydrogenase and related
JN214_RS00820	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS00835	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS00850	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
JN214_RS00865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS00870	COG1846	Transcriptional regulator
JN214_RS00895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS00895	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JN214_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS00925	COG4221	oxidoreductase activity
JN214_RS00955	COG2124	cytochrome p450
JN214_RS00960	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS00970	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS01005	COG1902	pentaerythritol trinitrate reductase activity
JN214_RS01005	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN214_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS01020	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS01045	COG2124	cytochrome p450
JN214_RS01050	COG1960	acyl-CoA dehydrogenase activity
JN214_RS01080	COG2910	NAD(P)H-binding
JN214_RS01085	COG2124	cytochrome p450
JN214_RS01090	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN214_RS01090	COG1902	pentaerythritol trinitrate reductase activity
JN214_RS01100	COG0574	Belongs to the PEP-utilizing enzyme family
JN214_RS01100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN214_RS01175	COG0574	Belongs to the PEP-utilizing enzyme family
JN214_RS01175	COG3848	Pyruvate phosphate dikinase
JN214_RS01180	COG0183	Belongs to the thiolase family
JN214_RS01185	COG1960	acyl-CoA dehydrogenase activity
JN214_RS01195	COG1309	transcriptional regulator
JN214_RS01210	COG1278	Cold shock
JN214_RS01220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN214_RS01230	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS01275	COG0277	FAD linked oxidase domain protein
JN214_RS01285	COG2267	carboxylic ester hydrolase activity
JN214_RS01290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS01300	COG1247	-acetyltransferase
JN214_RS01325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS01370	COG1309	transcriptional regulator
JN214_RS01430	COG0659	secondary active sulfate transmembrane transporter activity
JN214_RS01440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN214_RS01450	COG2124	cytochrome p450
JN214_RS01460	COG0714	Associated with various cellular activities
JN214_RS01480	COG0477	Major facilitator Superfamily
JN214_RS01500	COG0346	lactoylglutathione lyase activity
JN214_RS01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS01560	COG4552	Acetyltransferase involved in intracellular survival and related
JN214_RS01565	COG1960	acyl-CoA dehydrogenase activity
JN214_RS01570	COG1309	transcriptional regulator
JN214_RS01585	COG5651	PPE family
JN214_RS01615	COG1404	Belongs to the peptidase S8 family
JN214_RS01635	COG0702	epimerase
JN214_RS01650	COG0067	glutamate synthase
JN214_RS01650	COG0069	glutamate synthase activity
JN214_RS01650	COG0070	glutamate synthase
JN214_RS01670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JN214_RS01670	COG1796	DNA polymerase
JN214_RS01680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN214_RS01690	COG2072	flavoprotein involved in K transport
JN214_RS01730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN214_RS01750	COG1316	TRANSCRIPTIONal
JN214_RS01840	COG0561	phosphatase activity
JN214_RS01860	COG1216	Glycosyl transferase, family 2
JN214_RS01875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JN214_RS01885	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN214_RS01890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JN214_RS01895	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS01900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN214_RS01900	COG3321	synthase
JN214_RS01900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN214_RS01905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN214_RS01920	COG1960	acyl-CoA dehydrogenase activity
JN214_RS01960	COG0640	Transcriptional regulator
JN214_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS01980	COG0277	FAD linked oxidase domain protein
JN214_RS01995	COG1403	HNH endonuclease
JN214_RS02030	COG0604	alcohol dehydrogenase
JN214_RS02050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN214_RS02070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN214_RS02115	COG0745	RESPONSE REGULATOR receiver
JN214_RS02120	COG2205	protein histidine kinase activity
JN214_RS02130	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JN214_RS02175	COG5416	Lipopolysaccharide assembly protein A domain
JN214_RS02190	COG1174	glycine betaine transport
JN214_RS02205	COG0287	Prephenate dehydrogenase
JN214_RS02215	COG0590	tRNA wobble adenosine to inosine editing
JN214_RS02240	COG1511	domain protein
JN214_RS02285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS02290	COG2301	Belongs to the HpcH HpaI aldolase family
JN214_RS02295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN214_RS02305	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN214_RS02315	COG1396	sequence-specific DNA binding
JN214_RS02315	COG3800	Transcriptional regulator
JN214_RS02320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN214_RS02325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN214_RS02345	COG3804	dihydrodipicolinate reductase
JN214_RS02365	COG0596	Alpha beta hydrolase
JN214_RS02370	COG2124	cytochrome p450
JN214_RS02390	COG1793	dna ligase
JN214_RS02445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN214_RS02470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN214_RS02480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS02495	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN214_RS02500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JN214_RS02520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JN214_RS02525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JN214_RS02570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN214_RS02575	COG0121	glutamine amidotransferase
JN214_RS02585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN214_RS02600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN214_RS02605	COG1695	Transcriptional regulator
JN214_RS02630	COG0714	Associated with various cellular activities
JN214_RS02655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS02665	COG0693	protein deglycase activity
JN214_RS02670	COG2890	protein-(glutamine-N5) methyltransferase activity
JN214_RS02695	COG2172	sigma factor antagonist activity
JN214_RS02700	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS02705	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS02720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN214_RS02745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN214_RS02750	COG1408	metallophosphoesterase
JN214_RS02785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN214_RS02800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JN214_RS02835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN214_RS02855	COG0601	transmembrane transport
JN214_RS02860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN214_RS02920	COG1111	helicase
JN214_RS02920	COG1205	dead DEAH box helicase
JN214_RS02945	COG0470	DNA polymerase III
JN214_RS03000	COG2027	D-alanyl-D-alanine carboxypeptidase
JN214_RS03010	COG0037	tRNA processing
JN214_RS03035	COG0657	acetylesterase activity
JN214_RS03045	COG1403	HNH endonuclease
JN214_RS03050	COG1063	alcohol dehydrogenase
JN214_RS03060	COG2267	carboxylic ester hydrolase activity
JN214_RS03075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN214_RS03080	COG0302	gtp cyclohydrolase
JN214_RS03085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JN214_RS03090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JN214_RS03115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN214_RS03195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JN214_RS03230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JN214_RS03240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN214_RS03245	COG1121	(ABC) transporter
JN214_RS03255	COG1609	Transcriptional regulator
JN214_RS03260	COG1309	transcriptional regulator
JN214_RS03265	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03315	COG0436	Aminotransferase
JN214_RS03320	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03325	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03330	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03335	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS03340	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03355	COG0183	Belongs to the thiolase family
JN214_RS03385	COG1024	Enoyl-CoA hydratase
JN214_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS03415	COG0183	Belongs to the thiolase family
JN214_RS03420	COG2124	cytochrome p450
JN214_RS03425	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03430	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03435	COG2030	dehydratase
JN214_RS03455	COG2030	dehydratase
JN214_RS03460	COG1053	succinate dehydrogenase
JN214_RS03465	COG3971	2-oxopent-4-enoate hydratase activity
JN214_RS03470	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JN214_RS03475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN214_RS03490	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS03505	COG4638	Rieske (2fe-2S)
JN214_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS03545	COG2124	cytochrome p450
JN214_RS03565	COG3001	Fructosamine kinase
JN214_RS03575	COG0028	Belongs to the TPP enzyme family
JN214_RS03585	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS03590	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03595	COG1960	acyl-CoA dehydrogenase activity
JN214_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS03610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS03615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS03640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN214_RS03675	COG1024	Enoyl-CoA hydratase
JN214_RS03690	COG1316	TRANSCRIPTIONal
JN214_RS03760	COG0745	RESPONSE REGULATOR receiver
JN214_RS03765	COG2205	protein histidine kinase activity
JN214_RS03795	COG2124	cytochrome p450
JN214_RS03800	COG0300	oxidoreductase activity
JN214_RS03835	COG0667	Aldo Keto reductase
JN214_RS03870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN214_RS03890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JN214_RS03900	COG0477	Major facilitator Superfamily
JN214_RS03905	COG0477	Major facilitator Superfamily
JN214_RS03920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN214_RS03930	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN214_RS03935	COG0047	phosphoribosylformylglycinamidine synthase activity
JN214_RS03945	COG0204	Acyl-transferase
JN214_RS03950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN214_RS03965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN214_RS04005	COG1017	nitric oxide dioxygenase activity
JN214_RS04005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN214_RS04015	COG2837	iron assimilation
JN214_RS04065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JN214_RS04115	COG0745	RESPONSE REGULATOR receiver
JN214_RS04140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN214_RS04180	COG0640	Transcriptional regulator
JN214_RS04185	COG0590	tRNA wobble adenosine to inosine editing
JN214_RS04215	COG4974	Belongs to the 'phage' integrase family
JN214_RS04235	COG1609	Transcriptional regulator
JN214_RS04245	COG1309	transcriptional regulator
JN214_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS04315	COG2124	cytochrome p450
JN214_RS04320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN214_RS04325	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS04345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN214_RS04345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN214_RS04350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN214_RS04355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS04360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS04395	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04400	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04410	COG2267	carboxylic ester hydrolase activity
JN214_RS04415	COG3479	Phenolic acid decarboxylase
JN214_RS04420	COG0183	Belongs to the thiolase family
JN214_RS04425	COG1703	isobutyryl-CoA mutase activity
JN214_RS04430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN214_RS04440	COG4585	Histidine kinase
JN214_RS04450	COG0504	CTP synthase activity
JN214_RS04455	COG1053	succinate dehydrogenase
JN214_RS04465	COG2267	carboxylic ester hydrolase activity
JN214_RS04470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS04475	COG3384	dioxygenase
JN214_RS04480	COG1053	succinate dehydrogenase
JN214_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS04505	COG2132	Multicopper oxidase
JN214_RS04520	COG2197	response regulator
JN214_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS04580	COG1024	Enoyl-CoA hydratase
JN214_RS04585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS04610	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04625	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN214_RS04645	COG4638	Rieske (2fe-2S)
JN214_RS04665	COG1024	Enoyl-CoA hydratase
JN214_RS04670	COG0183	Belongs to the thiolase family
JN214_RS04675	COG1309	transcriptional regulator
JN214_RS04705	COG2124	cytochrome p450
JN214_RS04710	COG2084	Dehydrogenase
JN214_RS04750	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JN214_RS04800	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JN214_RS04800	COG0778	Nitroreductase
JN214_RS04805	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04810	COG1960	acyl-CoA dehydrogenase activity
JN214_RS04850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS04855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS04860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS04885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN214_RS04970	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS04995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS05015	COG0183	Belongs to the thiolase family
JN214_RS05020	COG1024	Enoyl-CoA hydratase
JN214_RS05020	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN214_RS05025	COG2813	Specifically methylates the guanine in position
JN214_RS05045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS05075	COG1061	Type III restriction enzyme res subunit
JN214_RS05115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN214_RS05120	COG3304	Inner membrane component domain
JN214_RS05125	COG1278	Cold shock
JN214_RS05140	COG0435	Glutathione S-transferase
JN214_RS05155	COG2814	Major facilitator Superfamily
JN214_RS05195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JN214_RS05220	COG0259	pyridoxamine-phosphate oxidase activity
JN214_RS05350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS05390	COG0581	inorganic phosphate transmembrane transporter activity
JN214_RS05415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS05450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN214_RS05480	COG4942	peptidase
JN214_RS05520	COG0138	bifunctional purine biosynthesis protein purh
JN214_RS05540	COG0656	L-ascorbic acid biosynthetic process
JN214_RS05550	COG1024	Enoyl-CoA hydratase
JN214_RS05565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN214_RS05570	COG1960	acyl-CoA dehydrogenase activity
JN214_RS05595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN214_RS05600	COG0521	Mo-molybdopterin cofactor biosynthetic process
JN214_RS05600	COG0315	cyclic pyranopterin monophosphate synthase activity
JN214_RS05605	COG1970	mechanosensitive ion channel activity
JN214_RS05620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN214_RS05625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JN214_RS05660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS05700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN214_RS05705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JN214_RS05710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN214_RS05710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN214_RS05745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN214_RS05755	COG1252	NADH dehydrogenase
JN214_RS05790	COG0438	transferase activity, transferring glycosyl groups
JN214_RS05790	COG0297	glycogen (starch) synthase activity
JN214_RS05830	COG0297	glycogen (starch) synthase activity
JN214_RS05845	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JN214_RS05895	COG0084	hydrolase, TatD family'
JN214_RS05910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JN214_RS05915	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS05920	COG0193	aminoacyl-tRNA hydrolase activity
JN214_RS05925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JN214_RS05970	COG1309	transcriptional regulator
JN214_RS05985	COG3956	TIGRFAM MazG family protein
JN214_RS06030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JN214_RS06035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JN214_RS06050	COG2205	protein histidine kinase activity
JN214_RS06055	COG0745	RESPONSE REGULATOR receiver
JN214_RS06105	COG3391	amine dehydrogenase activity
JN214_RS06110	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS06120	COG0121	glutamine amidotransferase
JN214_RS06170	COG1024	Enoyl-CoA hydratase
JN214_RS06180	COG0183	Belongs to the thiolase family
JN214_RS06185	COG2755	lipolytic protein G-D-S-L family
JN214_RS06190	COG0657	acetylesterase activity
JN214_RS06230	COG1331	Highly conserved protein containing a thioredoxin domain
JN214_RS06245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JN214_RS06255	COG0572	uridine kinase
JN214_RS06270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JN214_RS06320	COG2272	Belongs to the type-B carboxylesterase lipase family
JN214_RS06335	COG1570	exodeoxyribonuclease VII activity
JN214_RS06345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JN214_RS06355	COG0012	GTP binding
JN214_RS06425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JN214_RS06455	COG0574	Belongs to the PEP-utilizing enzyme family
JN214_RS06455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN214_RS06485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN214_RS06490	COG0702	epimerase
JN214_RS06500	COG1309	transcriptional regulator
JN214_RS06510	COG1960	acyl-CoA dehydrogenase activity
JN214_RS06515	COG1960	acyl-CoA dehydrogenase activity
JN214_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS06530	COG0714	Associated with various cellular activities
JN214_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS06550	COG2124	cytochrome p450
JN214_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS06580	COG0183	Belongs to the thiolase family
JN214_RS06585	COG1024	Enoyl-CoA hydratase
JN214_RS06595	COG1755	Isoprenylcysteine carboxyl methyltransferase
JN214_RS06605	COG0702	epimerase
JN214_RS06615	COG0702	epimerase
JN214_RS06620	COG1024	Enoyl-CoA hydratase
JN214_RS06625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS06635	COG2409	Drug exporters of the RND superfamily
JN214_RS06645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JN214_RS06660	COG3467	pyridoxamine 5'-phosphate
JN214_RS06725	COG1140	nitrate reductase beta subunit
JN214_RS06740	COG1217	gtp-binding protein TYPA
JN214_RS06755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN214_RS06765	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JN214_RS06780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN214_RS06790	COG0531	amino acid
JN214_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS06795	COG3321	synthase
JN214_RS06795	COG0604	alcohol dehydrogenase
JN214_RS06810	COG0529	Catalyzes the synthesis of activated sulfate
JN214_RS06815	COG2046	Belongs to the sulfate adenylyltransferase family
JN214_RS06830	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS06855	COG1309	transcriptional regulator
JN214_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS06890	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS06895	COG0477	Major facilitator Superfamily
JN214_RS06925	COG1611	Belongs to the LOG family
JN214_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS06940	COG0463	Glycosyl transferase, family 2
JN214_RS06950	COG0519	Catalyzes the synthesis of GMP from XMP
JN214_RS06965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JN214_RS06975	COG3559	Exporter of polyketide antibiotics
JN214_RS06980	COG1131	(ABC) transporter
JN214_RS06985	COG1309	transcriptional regulator
JN214_RS07000	COG5662	AntiSigma factor
JN214_RS07005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN214_RS07010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN214_RS07035	COG2239	Acts as a magnesium transporter
JN214_RS07075	COG0598	Magnesium transport protein CorA
JN214_RS07080	COG0039	L-malate dehydrogenase activity
JN214_RS07170	COG2124	cytochrome p450
JN214_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07235	COG4584	PFAM Integrase catalytic
JN214_RS07245	COG0492	ferredoxin-NADP+ reductase activity
JN214_RS07250	COG0277	FAD linked oxidase domain protein
JN214_RS07265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS07415	COG3631	Ketosteroid isomerase-related protein
JN214_RS07420	COG0494	nUDIX hydrolase
JN214_RS07445	COG0018	arginyl-trna synthetase
JN214_RS07450	COG0019	diaminopimelate decarboxylase activity
JN214_RS07455	COG0460	homoserine dehydrogenase
JN214_RS07465	COG0083	homoserine kinase activity
JN214_RS07470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JN214_RS07485	COG2890	protein-(glutamine-N5) methyltransferase activity
JN214_RS07505	COG0356	it plays a direct role in the translocation of protons across the membrane
JN214_RS07510	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN214_RS07520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JN214_RS07520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN214_RS07555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JN214_RS07575	COG5651	PPE family
JN214_RS07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JN214_RS07620	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JN214_RS07645	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN214_RS07655	COG0058	SHG alpha-glucan phosphorylase activity
JN214_RS07665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JN214_RS07695	COG1234	tRNA 3'-trailer cleavage
JN214_RS07700	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JN214_RS07705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JN214_RS07730	COG3011	Protein conserved in bacteria
JN214_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07765	COG1960	acyl-CoA dehydrogenase activity
JN214_RS07775	COG0183	Belongs to the thiolase family
JN214_RS07780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS07785	COG1960	acyl-CoA dehydrogenase activity
JN214_RS07790	COG1802	Transcriptional regulator
JN214_RS07825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN214_RS07835	COG1024	Enoyl-CoA hydratase
JN214_RS07840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN214_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS07865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN214_RS07875	COG1024	Enoyl-CoA hydratase
JN214_RS07900	COG1960	acyl-CoA dehydrogenase activity
JN214_RS07910	COG0183	Belongs to the thiolase family
JN214_RS07960	COG4638	Rieske (2fe-2S)
JN214_RS07970	COG2072	flavoprotein involved in K transport
JN214_RS07990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN214_RS08005	COG1309	transcriptional regulator
JN214_RS08025	COG2124	cytochrome p450
JN214_RS08030	COG0657	acetylesterase activity
JN214_RS08035	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08040	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08065	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08070	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08075	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08080	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08110	COG2124	cytochrome p450
JN214_RS08170	COG3757	hydrolase, family 25
JN214_RS08175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN214_RS08175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN214_RS08175	COG3321	synthase
JN214_RS08180	COG0736	holo-[acyl-carrier-protein] synthase activity
JN214_RS08245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JN214_RS08395	COG2409	Drug exporters of the RND superfamily
JN214_RS08400	COG0697	spore germination
JN214_RS08405	COG1376	ErfK ybiS ycfS ynhG family protein
JN214_RS08425	COG0433	COG0433 Predicted ATPase
JN214_RS08430	COG0300	oxidoreductase activity
JN214_RS08450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN214_RS08460	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08465	COG2030	dehydratase
JN214_RS08485	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN214_RS08505	COG0657	acetylesterase activity
JN214_RS08520	COG2937	Belongs to the GPAT DAPAT family
JN214_RS08535	COG0629	single-stranded DNA binding
JN214_RS08545	COG2902	Dehydrogenase
JN214_RS08565	COG0366	Alpha amylase catalytic
JN214_RS08570	COG2346	COG2346, Truncated hemoglobins
JN214_RS08595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JN214_RS08600	COG0698	ribose 5-phosphate isomerase
JN214_RS08615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN214_RS08635	COG0740	serine-type endopeptidase activity
JN214_RS08640	COG0740	serine-type endopeptidase activity
JN214_RS08645	COG2040	homocysteine
JN214_RS08660	COG0674	pyruvate-flavodoxin oxidoreductase activity
JN214_RS08660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JN214_RS08665	COG1013	pyruvate-flavodoxin oxidoreductase activity
JN214_RS08675	COG1388	LysM domain
JN214_RS08680	COG3268	Saccharopine dehydrogenase
JN214_RS08685	COG0525	valine-tRNA ligase activity
JN214_RS08690	COG0285	dihydrofolate synthase activity
JN214_RS08700	COG0105	UTP biosynthetic process
JN214_RS08705	COG1530	ribonuclease E activity
JN214_RS08720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JN214_RS08750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JN214_RS08750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN214_RS08755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN214_RS08760	COG5002	protein histidine kinase activity
JN214_RS08765	COG0668	transmembrane transport
JN214_RS08770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN214_RS08775	COG0542	response to heat
JN214_RS08785	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JN214_RS08790	COG0799	negative regulation of ribosome biogenesis
JN214_RS08800	COG2755	lipolytic protein G-D-S-L family
JN214_RS08825	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS08830	COG5651	PPE family
JN214_RS08835	COG2409	Drug exporters of the RND superfamily
JN214_RS08855	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08860	COG1960	acyl-CoA dehydrogenase activity
JN214_RS08865	COG1596	polysaccharide export
JN214_RS08865	COG1555	photosystem II stabilization
JN214_RS08895	COG1305	Transglutaminase-like
JN214_RS08900	COG1733	regulation of RNA biosynthetic process
JN214_RS08915	COG1234	tRNA 3'-trailer cleavage
JN214_RS08920	COG0517	IMP dehydrogenase activity
JN214_RS08930	COG0481	GTPase activity
JN214_RS08945	COG3387	PFAM Glycoside hydrolase 15-related
JN214_RS08955	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JN214_RS08960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JN214_RS08965	COG4208	sulfate ABC transporter
JN214_RS08970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN214_RS08980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN214_RS09000	COG1169	isochorismate synthase
JN214_RS09010	COG2072	flavoprotein involved in K transport
JN214_RS09065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN214_RS09080	COG2124	cytochrome p450
JN214_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS09125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN214_RS09140	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS09160	COG1063	alcohol dehydrogenase
JN214_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS09215	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09230	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS09275	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09285	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09290	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09295	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN214_RS09330	COG1024	Enoyl-CoA hydratase
JN214_RS09340	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09345	COG1024	Enoyl-CoA hydratase
JN214_RS09355	COG1024	Enoyl-CoA hydratase
JN214_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS09365	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS09395	COG1024	Enoyl-CoA hydratase
JN214_RS09410	COG1960	acyl-CoA dehydrogenase activity
JN214_RS09425	COG1024	Enoyl-CoA hydratase
JN214_RS09495	COG4948	Mandelate Racemase Muconate Lactonizing
JN214_RS09505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN214_RS09540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN214_RS09545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN214_RS09615	COG0281	malic enzyme
JN214_RS09620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JN214_RS09635	COG1309	transcriptional regulator
JN214_RS09655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JN214_RS09660	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN214_RS09665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN214_RS09680	COG3321	synthase
JN214_RS09680	COG0604	alcohol dehydrogenase
JN214_RS09685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN214_RS09695	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JN214_RS09715	COG1595	DNA-templated transcription, initiation
JN214_RS09730	COG1420	regulation of RNA biosynthetic process
JN214_RS09735	COG0484	heat shock protein binding
JN214_RS09770	COG1982	Orn Lys Arg decarboxylase major
JN214_RS09780	COG1381	Involved in DNA repair and RecF pathway recombination
JN214_RS09805	COG0423	glycine-tRNA ligase activity
JN214_RS09850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS09855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS09865	COG1045	serine acetyltransferase
JN214_RS09875	COG2855	membrane
JN214_RS09885	COG4424	Sulfotransferase
JN214_RS09895	COG0243	molybdopterin cofactor binding
JN214_RS09910	COG1716	ATPase activity
JN214_RS09910	COG1131	(ABC) transporter
JN214_RS09910	COG0842	Transport permease protein
JN214_RS09935	COG0531	amino acid
JN214_RS09950	COG1175	transmembrane transport
JN214_RS09990	COG2267	carboxylic ester hydrolase activity
JN214_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS10040	COG3903	Transcriptional regulator
JN214_RS10040	COG3629	intracellular signal transduction
JN214_RS10045	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS10045	COG2172	sigma factor antagonist activity
JN214_RS10045	COG2208	phosphoserine phosphatase activity
JN214_RS10065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS10070	COG2226	methyltransferase
JN214_RS10150	COG2132	Multicopper oxidase
JN214_RS10175	COG0596	Alpha beta hydrolase
JN214_RS10190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN214_RS10205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS10245	COG0798	PFAM Bile acid sodium symporter
JN214_RS10280	COG0438	transferase activity, transferring glycosyl groups
JN214_RS10295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN214_RS10310	COG0657	acetylesterase activity
JN214_RS10315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN214_RS10330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN214_RS10350	COG1309	transcriptional regulator
JN214_RS10400	COG1487	ribonuclease activity
JN214_RS10410	COG4584	PFAM Integrase catalytic
JN214_RS10445	COG1960	acyl-CoA dehydrogenase activity
JN214_RS10450	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN214_RS10465	COG2072	flavoprotein involved in K transport
JN214_RS10570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS10590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN214_RS10655	COG0596	Alpha beta hydrolase
JN214_RS10665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JN214_RS10825	COG0321	lipoyl(octanoyl) transferase activity
JN214_RS10860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN214_RS10870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN214_RS10875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JN214_RS10880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN214_RS10910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN214_RS10920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN214_RS10955	COG1845	cytochrome c oxidase, subunit III
JN214_RS10985	COG1022	Amp-dependent synthetase and ligase
JN214_RS11000	COG0003	Pfam Anion-transporting ATPase
JN214_RS11030	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JN214_RS11050	COG0142	geranyltranstransferase activity
JN214_RS11090	COG0768	penicillin binding
JN214_RS11130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN214_RS11145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN214_RS11190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN214_RS11200	COG0167	dihydroorotate dehydrogenase activity
JN214_RS11235	COG1218	3'(2'),5'-bisphosphate nucleotidase
JN214_RS11240	COG0215	cysteine-tRNA ligase activity
JN214_RS11270	COG3321	synthase
JN214_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS11270	COG0604	alcohol dehydrogenase
JN214_RS11275	COG2124	cytochrome p450
JN214_RS11290	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS11355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS11435	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JN214_RS11455	COG2378	regulation of single-species biofilm formation
JN214_RS11495	COG0300	oxidoreductase activity
JN214_RS11540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN214_RS11575	COG0412	Dienelactone hydrolase
JN214_RS11610	COG3321	synthase
JN214_RS11610	COG0604	alcohol dehydrogenase
JN214_RS11625	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS11650	COG0714	Associated with various cellular activities
JN214_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS11710	COG2272	Belongs to the type-B carboxylesterase lipase family
JN214_RS11720	COG3265	gluconokinase activity
JN214_RS11730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS11755	COG1335	isochorismatase
JN214_RS11770	COG1595	DNA-templated transcription, initiation
JN214_RS11780	COG1175	transmembrane transport
JN214_RS11785	COG0395	ABC-type sugar transport system, permease component
JN214_RS11790	COG3842	ATPase activity
JN214_RS11795	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN214_RS11820	COG2837	iron assimilation
JN214_RS11830	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JN214_RS11860	COG0667	Aldo Keto reductase
JN214_RS11870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN214_RS11890	COG1960	acyl-CoA dehydrogenase activity
JN214_RS11940	COG0523	cobalamin synthesis protein
JN214_RS11945	COG1946	Acyl-CoA thioesterase
JN214_RS11950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN214_RS11965	COG1231	oxidoreductase activity
JN214_RS12000	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS12020	COG1595	DNA-templated transcription, initiation
JN214_RS12065	COG2204	response regulator
JN214_RS12095	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN214_RS12110	COG0583	DNA-binding transcription factor activity
JN214_RS12140	COG0545	Peptidyl-prolyl cis-trans isomerase
JN214_RS12145	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN214_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS12175	COG2301	Belongs to the HpcH HpaI aldolase family
JN214_RS12185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN214_RS12200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS12205	COG1643	Atp-dependent helicase
JN214_RS12215	COG1024	Enoyl-CoA hydratase
JN214_RS12235	COG1063	alcohol dehydrogenase
JN214_RS12285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN214_RS12285	COG0723	plastoquinol--plastocyanin reductase activity
JN214_RS12295	COG1376	ErfK ybiS ycfS ynhG family protein
JN214_RS12310	COG3757	hydrolase, family 25
JN214_RS12315	COG0438	transferase activity, transferring glycosyl groups
JN214_RS12320	COG2226	methyltransferase
JN214_RS12340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JN214_RS12355	COG1024	Enoyl-CoA hydratase
JN214_RS12360	COG1309	transcriptional regulator
JN214_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS12380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS12395	COG1960	acyl-CoA dehydrogenase activity
JN214_RS12400	COG3391	amine dehydrogenase activity
JN214_RS12415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS12420	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS12475	COG4977	sequence-specific DNA binding
JN214_RS12485	COG1733	regulation of RNA biosynthetic process
JN214_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS12510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN214_RS12545	COG0640	Transcriptional regulator
JN214_RS12565	COG1233	COG1233 Phytoene dehydrogenase and related
JN214_RS12575	COG1942	4-Oxalocrotonate Tautomerase
JN214_RS12605	COG1950	PFAM Membrane protein of
JN214_RS12630	COG2814	Major facilitator Superfamily
JN214_RS12635	COG1546	Belongs to the CinA family
JN214_RS12635	COG1058	Belongs to the CinA family
JN214_RS12660	COG1063	alcohol dehydrogenase
JN214_RS12670	COG2070	2-Nitropropane dioxygenase
JN214_RS12710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN214_RS12755	COG0174	glutamine synthetase
JN214_RS12765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN214_RS12775	COG2193	ferroxidase activity
JN214_RS12785	COG1024	Enoyl-CoA hydratase
JN214_RS12810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN214_RS12870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS12875	COG1968	undecaprenyl-diphosphatase activity
JN214_RS12880	COG4221	oxidoreductase activity
JN214_RS12935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS12945	COG1252	NADH dehydrogenase
JN214_RS12965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JN214_RS12980	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS12985	COG1960	acyl-CoA dehydrogenase activity
JN214_RS12990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN214_RS12995	COG1253	flavin adenine dinucleotide binding
JN214_RS13000	COG1253	flavin adenine dinucleotide binding
JN214_RS13095	COG3976	FMN-binding domain protein
JN214_RS13095	COG1053	succinate dehydrogenase
JN214_RS13125	COG1285	pathogenesis
JN214_RS13135	COG5651	PPE family
JN214_RS13180	COG1404	Belongs to the peptidase S8 family
JN214_RS13250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN214_RS13270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS13295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN214_RS13300	COG0022	dehydrogenase e1 component
JN214_RS13310	COG1024	Enoyl-CoA hydratase
JN214_RS13315	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS13325	COG1053	succinate dehydrogenase
JN214_RS13355	COG2813	Specifically methylates the guanine in position
JN214_RS13420	COG4221	oxidoreductase activity
JN214_RS13450	COG4221	oxidoreductase activity
JN214_RS13455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS13460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN214_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS13495	COG2226	methyltransferase
JN214_RS13510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS13530	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS13560	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS13565	COG2072	flavoprotein involved in K transport
JN214_RS13585	COG2030	dehydratase
JN214_RS13590	COG1960	acyl-CoA dehydrogenase activity
JN214_RS13595	COG1960	acyl-CoA dehydrogenase activity
JN214_RS13605	COG1131	(ABC) transporter
JN214_RS13605	COG0842	Transport permease protein
JN214_RS13605	COG1716	ATPase activity
JN214_RS13610	COG0657	acetylesterase activity
JN214_RS13620	COG0243	molybdopterin cofactor binding
JN214_RS13640	COG2267	carboxylic ester hydrolase activity
JN214_RS13665	COG2072	flavoprotein involved in K transport
JN214_RS13680	COG0346	lactoylglutathione lyase activity
JN214_RS13730	COG0657	acetylesterase activity
JN214_RS13745	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS13750	COG2072	flavoprotein involved in K transport
JN214_RS13755	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS13760	COG1960	acyl-CoA dehydrogenase activity
JN214_RS13780	COG0657	acetylesterase activity
JN214_RS13810	COG1053	succinate dehydrogenase
JN214_RS13875	COG2271	Major facilitator Superfamily
JN214_RS13880	COG0189	ligase activity
JN214_RS13880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN214_RS13910	COG1305	Transglutaminase-like
JN214_RS13920	COG1278	Cold shock
JN214_RS13990	COG0789	Transcriptional regulator
JN214_RS14065	COG2239	Acts as a magnesium transporter
JN214_RS14085	COG2132	Multicopper oxidase
JN214_RS14090	COG2226	methyltransferase
JN214_RS14100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN214_RS14170	COG1672	PFAM Archaeal ATPase
JN214_RS14170	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN214_RS14190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN214_RS14200	COG0713	ATP synthesis coupled electron transport
JN214_RS14205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JN214_RS14220	COG4584	PFAM Integrase catalytic
JN214_RS14230	COG5002	protein histidine kinase activity
JN214_RS14240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN214_RS14290	COG0596	Alpha beta hydrolase
JN214_RS14290	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN214_RS14300	COG0745	RESPONSE REGULATOR receiver
JN214_RS14305	COG2205	protein histidine kinase activity
JN214_RS14315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JN214_RS14335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN214_RS14350	COG0604	alcohol dehydrogenase
JN214_RS14350	COG3321	synthase
JN214_RS14380	COG1937	Protein conserved in bacteria
JN214_RS14390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN214_RS14400	COG0019	diaminopimelate decarboxylase activity
JN214_RS14425	COG4584	PFAM Integrase catalytic
JN214_RS14430	COG2161	toxin-antitoxin pair type II binding
JN214_RS14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN214_RS14485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN214_RS14495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JN214_RS14520	COG0494	nUDIX hydrolase
JN214_RS14545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JN214_RS14560	COG0647	UMP catabolic process
JN214_RS14575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JN214_RS14580	COG2094	Belongs to the DNA glycosylase MPG family
JN214_RS14590	COG1131	(ABC) transporter
JN214_RS14600	COG1309	transcriptional regulator
JN214_RS14605	COG2835	tetraacyldisaccharide 4'-kinase activity
JN214_RS14635	COG0300	oxidoreductase activity
JN214_RS14640	COG4948	Mandelate Racemase Muconate Lactonizing
JN214_RS14650	COG0488	(ABC) transporter
JN214_RS14665	COG3321	synthase
JN214_RS14665	COG3321	synthase
JN214_RS14665	COG0604	alcohol dehydrogenase
JN214_RS14665	COG0604	alcohol dehydrogenase
JN214_RS14670	COG0604	alcohol dehydrogenase
JN214_RS14670	COG3321	synthase
JN214_RS14675	COG0604	alcohol dehydrogenase
JN214_RS14675	COG3321	synthase
JN214_RS14685	COG0165	Argininosuccinate lyase
JN214_RS14700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JN214_RS14715	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JN214_RS14720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JN214_RS14725	COG0072	phenylalanine-tRNA ligase activity
JN214_RS14725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN214_RS14730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JN214_RS14785	COG1309	transcriptional regulator
JN214_RS14795	COG2890	protein-(glutamine-N5) methyltransferase activity
JN214_RS14865	COG1131	(ABC) transporter
JN214_RS14865	COG0842	Transport permease protein
JN214_RS14865	COG1716	ATPase activity
JN214_RS14875	COG5343	regulation of RNA biosynthetic process
JN214_RS14905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN214_RS14915	COG0237	dephospho-CoA kinase activity
JN214_RS14915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JN214_RS14925	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JN214_RS14975	COG1271	oxidase subunit
JN214_RS14980	COG1294	oxidase, subunit
JN214_RS14985	COG4988	ABC transporter
JN214_RS14990	COG1132	(ABC) transporter
JN214_RS15005	COG1946	Acyl-CoA thioesterase
JN214_RS15045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN214_RS15055	COG0387	Pfam Sodium calcium exchanger
JN214_RS15060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JN214_RS15070	COG0483	inositol monophosphate 1-phosphatase activity
JN214_RS15080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN214_RS15085	COG0131	Imidazoleglycerol-phosphate dehydratase
JN214_RS15095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN214_RS15105	COG0157	Belongs to the NadC ModD family
JN214_RS15165	COG5002	protein histidine kinase activity
JN214_RS15170	COG0668	transmembrane transport
JN214_RS15195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN214_RS15205	COG0791	NLP P60 protein
JN214_RS15205	COG3883	PFAM NLP P60 protein
JN214_RS15245	COG0671	phosphoesterase, PA-phosphatase related
JN214_RS15275	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS15300	COG0300	oxidoreductase activity
JN214_RS15310	COG2346	COG2346, Truncated hemoglobins
JN214_RS15330	COG0252	asparaginase activity
JN214_RS15340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JN214_RS15350	COG2070	2-Nitropropane dioxygenase
JN214_RS15415	COG2755	lipolytic protein G-D-S-L family
JN214_RS15415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN214_RS15430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN214_RS15435	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JN214_RS15460	COG4221	oxidoreductase activity
JN214_RS15510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN214_RS15555	COG2205	protein histidine kinase activity
JN214_RS15560	COG0745	RESPONSE REGULATOR receiver
JN214_RS15595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JN214_RS15600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN214_RS15615	COG2304	oxidoreductase activity
JN214_RS15625	COG0714	Associated with various cellular activities
JN214_RS15635	COG0791	NLP P60 protein
JN214_RS15635	COG3883	PFAM NLP P60 protein
JN214_RS15645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN214_RS15650	COG1309	transcriptional regulator
JN214_RS15660	COG0488	(ABC) transporter
JN214_RS15670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN214_RS15675	COG1960	acyl-CoA dehydrogenase activity
JN214_RS15700	COG0251	oxidation-reduction process
JN214_RS15715	COG0183	Belongs to the thiolase family
JN214_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS15795	COG0657	acetylesterase activity
JN214_RS15855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN214_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS15895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN214_RS15920	COG2151	metal-sulfur cluster biosynthetic enzyme
JN214_RS15925	COG0822	iron-sulfur transferase activity
JN214_RS15935	COG0396	ATPase activity
JN214_RS15960	COG1131	(ABC) transporter
JN214_RS15995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JN214_RS16020	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN214_RS16025	COG0667	Aldo Keto reductase
JN214_RS16030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JN214_RS16070	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS16075	COG0657	acetylesterase activity
JN214_RS16110	COG1660	Displays ATPase and GTPase activities
JN214_RS16115	COG0322	excinuclease ABC activity
JN214_RS16140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN214_RS16205	COG0657	acetylesterase activity
JN214_RS16235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JN214_RS16265	COG0505	Belongs to the CarA family
JN214_RS16285	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JN214_RS16295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN214_RS16325	COG2188	Transcriptional regulator
JN214_RS16370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JN214_RS16395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN214_RS16400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JN214_RS16405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JN214_RS16415	COG0432	Pfam Uncharacterised protein family UPF0047
JN214_RS16480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JN214_RS16500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN214_RS16505	COG0235	Class ii aldolase
JN214_RS16510	COG1396	sequence-specific DNA binding
JN214_RS16545	COG1403	HNH endonuclease
JN214_RS16550	COG0124	histidyl-tRNA synthetase
JN214_RS16555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN214_RS16570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN214_RS16575	COG0747	negative chemotaxis
JN214_RS16580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JN214_RS16585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JN214_RS16600	COG1022	Amp-dependent synthetase and ligase
JN214_RS16600	COG3320	Male sterility
JN214_RS16650	COG3766	membrane
JN214_RS16670	COG1946	Acyl-CoA thioesterase
JN214_RS16695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN214_RS16720	COG0667	Aldo Keto reductase
JN214_RS16725	COG4762	Protein conserved in bacteria
JN214_RS16740	COG2070	2-Nitropropane dioxygenase
JN214_RS16780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN214_RS16790	COG3485	protocatechuate 3,4-dioxygenase
JN214_RS16830	COG1414	Transcriptional regulator
JN214_RS16840	COG1309	transcriptional regulator
JN214_RS16845	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS16850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN214_RS16860	COG0753	catalase activity
JN214_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS16885	COG1024	Enoyl-CoA hydratase
JN214_RS16980	COG1511	domain protein
JN214_RS17005	COG4689	acetoacetate decarboxylase
JN214_RS17040	COG1309	transcriptional regulator
JN214_RS17060	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS17120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN214_RS17130	COG3253	May function as heme-dependent peroxidase
JN214_RS17170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JN214_RS17175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN214_RS17180	COG0531	amino acid
JN214_RS17185	COG0569	domain protein
JN214_RS17235	COG0483	inositol monophosphate 1-phosphatase activity
JN214_RS17330	COG1388	LysM domain
JN214_RS17345	COG1960	acyl-CoA dehydrogenase activity
JN214_RS17350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JN214_RS17360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JN214_RS17375	COG1196	nuclear chromosome segregation
JN214_RS17385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN214_RS17425	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN214_RS17440	COG1842	Phage shock protein A
JN214_RS17455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JN214_RS17460	COG1674	ftsk spoiiie
JN214_RS17485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN214_RS17495	COG3214	Protein conserved in bacteria
JN214_RS17520	COG1960	acyl-CoA dehydrogenase activity
JN214_RS17525	COG1960	acyl-CoA dehydrogenase activity
JN214_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS17540	COG4770	biotin carboxylase activity
JN214_RS17565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN214_RS17615	COG0686	Belongs to the AlaDH PNT family
JN214_RS17630	COG1185	polyribonucleotide nucleotidyltransferase activity
JN214_RS17660	COG1960	acyl-CoA dehydrogenase activity
JN214_RS17665	COG0183	Belongs to the thiolase family
JN214_RS17670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JN214_RS17675	COG2977	Belongs to the P-Pant transferase superfamily
JN214_RS17680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN214_RS17715	COG0534	Mate efflux family protein
JN214_RS17720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JN214_RS17730	COG0481	GTPase activity
JN214_RS17770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN214_RS17770	COG1648	precorrin-2 dehydrogenase activity
JN214_RS17795	COG0579	oxidoreductase
JN214_RS17810	COG0735	belongs to the Fur family
JN214_RS17815	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JN214_RS17820	COG0375	protein maturation
JN214_RS17870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JN214_RS17880	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN214_RS17885	COG0309	Hydrogenase expression formation protein (HypE)
JN214_RS17905	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JN214_RS17920	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS17930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN214_RS17945	COG1492	cobalamin metabolic process
JN214_RS17970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JN214_RS17975	COG0750	zinc metalloprotease
JN214_RS17980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JN214_RS18000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JN214_RS18005	COG0575	Belongs to the CDS family
JN214_RS18025	COG0745	RESPONSE REGULATOR receiver
JN214_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS18065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN214_RS18090	COG0154	amidase activity
JN214_RS18100	COG0052	Belongs to the universal ribosomal protein uS2 family
JN214_RS18140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JN214_RS18150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN214_RS18165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JN214_RS18185	COG0336	Belongs to the RNA methyltransferase TrmD family
JN214_RS18190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JN214_RS18200	COG0228	four-way junction DNA binding
JN214_RS18210	COG1686	Belongs to the peptidase S11 family
JN214_RS18255	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JN214_RS18275	COG1196	nuclear chromosome segregation
JN214_RS18290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN214_RS18300	COG0571	ribonuclease III activity
JN214_RS18315	COG0701	Predicted permease
JN214_RS18320	COG0028	Belongs to the TPP enzyme family
JN214_RS18330	COG0742	ribosomal rna small subunit methyltransferase
JN214_RS18345	COG0657	acetylesterase activity
JN214_RS18365	COG1461	Dihydroxyacetone kinase
JN214_RS18410	COG3321	synthase
JN214_RS18410	COG0604	alcohol dehydrogenase
JN214_RS18430	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN214_RS18435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN214_RS18440	COG1920	GTP binding
JN214_RS18445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JN214_RS18490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN214_RS18495	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN214_RS18500	COG2271	Major facilitator Superfamily
JN214_RS18505	COG2271	Major facilitator Superfamily
JN214_RS18510	COG0473	3-isopropylmalate dehydrogenase activity
JN214_RS18525	COG0655	NAD(P)H dehydrogenase (quinone) activity
JN214_RS18540	COG0028	Belongs to the TPP enzyme family
JN214_RS18550	COG2259	Doxx family
JN214_RS18575	COG1192	Involved in chromosome partitioning
JN214_RS18580	COG0205	6-phosphofructokinase activity
JN214_RS18625	COG0626	cystathionine gamma-synthase activity
JN214_RS18675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN214_RS18725	COG0142	geranyltranstransferase activity
JN214_RS18755	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JN214_RS18795	COG1819	glycosyl
JN214_RS18800	COG1304	FMN binding
JN214_RS18805	COG2409	Drug exporters of the RND superfamily
JN214_RS18815	COG0415	Belongs to the DNA photolyase family
JN214_RS18825	COG0110	maltose O-acetyltransferase activity
JN214_RS18830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN214_RS18855	COG1024	Enoyl-CoA hydratase
JN214_RS18865	COG1119	ATPase activity
JN214_RS18875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN214_RS18905	COG1309	transcriptional regulator
JN214_RS18915	COG2072	flavoprotein involved in K transport
JN214_RS18920	COG1309	transcriptional regulator
JN214_RS18995	COG2186	Transcriptional regulator
JN214_RS19010	COG1960	acyl-CoA dehydrogenase activity
JN214_RS19020	COG1793	dna ligase
JN214_RS19025	COG0443	Heat shock 70 kDa protein
JN214_RS19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS19040	COG0183	Belongs to the thiolase family
JN214_RS19045	COG1024	Enoyl-CoA hydratase
JN214_RS19050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS19090	COG2076	Multidrug Resistance protein
JN214_RS19140	COG4638	Rieske (2fe-2S)
JN214_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS19170	COG4638	Rieske (2fe-2S)
JN214_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS19200	COG3654	unkown
JN214_RS19220	COG0477	Major facilitator Superfamily
JN214_RS19230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN214_RS19235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN214_RS19255	COG2301	Belongs to the HpcH HpaI aldolase family
JN214_RS19270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JN214_RS19305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN214_RS19370	COG4638	Rieske (2fe-2S)
JN214_RS19380	COG1716	ATPase activity
JN214_RS19380	COG1131	(ABC) transporter
JN214_RS19380	COG0842	Transport permease protein
JN214_RS19390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN214_RS19390	COG2755	lipolytic protein G-D-S-L family
JN214_RS19450	COG0243	molybdopterin cofactor binding
JN214_RS19455	COG1309	transcriptional regulator
JN214_RS19475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JN214_RS19480	COG2177	Part of the ABC transporter FtsEX involved in
JN214_RS19485	COG2884	Cell division ATP-binding protein ftsE
JN214_RS19495	COG0668	transmembrane transport
JN214_RS19505	COG0493	'glutamate synthase
JN214_RS19545	COG0483	inositol monophosphate 1-phosphatase activity
JN214_RS19555	COG1960	acyl-CoA dehydrogenase activity
JN214_RS19560	COG0667	Aldo Keto reductase
JN214_RS19565	COG0604	alcohol dehydrogenase
JN214_RS19585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS19590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN214_RS19600	COG1960	acyl-CoA dehydrogenase activity
JN214_RS19615	COG2353	YceI-like domain
JN214_RS19635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN214_RS19655	COG1034	ATP synthesis coupled electron transport
JN214_RS19660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN214_RS19675	COG0713	ATP synthesis coupled electron transport
JN214_RS19705	COG0714	Associated with various cellular activities
JN214_RS19755	COG0297	glycogen (starch) synthase activity
JN214_RS19770	COG2201	protein-glutamate methylesterase activity
JN214_RS19810	COG3237	CsbD-like
JN214_RS19820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JN214_RS19820	COG2111	Na H antiporter
JN214_RS19825	COG1006	Multisubunit Na H antiporter MnhC subunit
JN214_RS19840	COG1320	monovalent cation:proton antiporter activity
JN214_RS19845	COG2212	antiporter activity
JN214_RS19865	COG0028	Belongs to the TPP enzyme family
JN214_RS19870	COG1573	uracil-dna glycosylase
JN214_RS19925	COG0789	Transcriptional regulator
JN214_RS19935	COG3707	response regulator
JN214_RS19945	COG2197	response regulator
JN214_RS20025	COG0386	Belongs to the glutathione peroxidase family
JN214_RS20050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JN214_RS20060	COG0783	Belongs to the Dps family
JN214_RS20070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS20120	COG3480	Lon protease (S16) C-terminal proteolytic domain
JN214_RS20135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN214_RS20160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN214_RS20180	COG0596	Alpha beta hydrolase
JN214_RS20230	COG0513	Belongs to the DEAD box helicase family
JN214_RS20245	COG0406	alpha-ribazole phosphatase activity
JN214_RS20280	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN214_RS20300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JN214_RS20305	COG1063	alcohol dehydrogenase
JN214_RS20320	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS20330	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS20345	COG1403	HNH endonuclease
JN214_RS20355	COG2135	peptidase activity
JN214_RS20360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JN214_RS20365	COG1162	GTPase activity
JN214_RS20370	COG1733	regulation of RNA biosynthetic process
JN214_RS20375	COG0183	Belongs to the thiolase family
JN214_RS20390	COG1309	transcriptional regulator
JN214_RS20425	COG2020	methyltransferase activity
JN214_RS20430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JN214_RS20440	COG0653	protein targeting
JN214_RS20445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JN214_RS20455	COG5401	PFAM Sporulation and spore germination
JN214_RS20460	COG5002	protein histidine kinase activity
JN214_RS20460	COG5000	phosphorelay sensor kinase activity
JN214_RS20475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN214_RS20495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN214_RS20500	COG0531	amino acid
JN214_RS20505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS20510	COG1482	cell wall glycoprotein biosynthetic process
JN214_RS20520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN214_RS20560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN214_RS20575	COG1316	TRANSCRIPTIONal
JN214_RS20600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS20605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS20645	COG0784	Response regulator, receiver
JN214_RS20650	COG4251	negative regulation of phosphorylation
JN214_RS20665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JN214_RS20670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JN214_RS20690	COG1053	succinate dehydrogenase
JN214_RS20695	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS20710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN214_RS20720	COG0424	maF-like protein
JN214_RS20735	COG4770	biotin carboxylase activity
JN214_RS20740	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS20770	COG1522	sequence-specific DNA binding
JN214_RS20780	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS20785	COG1309	transcriptional regulator
JN214_RS20790	COG1201	RNA secondary structure unwinding
JN214_RS20825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN214_RS20835	COG0564	pseudouridine synthase activity
JN214_RS20840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JN214_RS20855	COG0657	acetylesterase activity
JN214_RS20860	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN214_RS20860	COG1473	amidohydrolase
JN214_RS20865	COG1473	amidohydrolase
JN214_RS20880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN214_RS20885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JN214_RS20890	COG3511	phospholipase C
JN214_RS20900	COG2304	oxidoreductase activity
JN214_RS20905	COG2304	oxidoreductase activity
JN214_RS20940	COG2009	succinate dehydrogenase
JN214_RS20950	COG1053	succinate dehydrogenase
JN214_RS20955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JN214_RS20970	COG1595	DNA-templated transcription, initiation
JN214_RS20975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN214_RS20985	COG1686	Belongs to the peptidase S11 family
JN214_RS20990	COG2814	Major facilitator Superfamily
JN214_RS21005	COG1295	ribonuclease BN
JN214_RS21030	COG2873	o-acetylhomoserine
JN214_RS21080	COG1131	(ABC) transporter
JN214_RS21080	COG1716	ATPase activity
JN214_RS21080	COG0842	Transport permease protein
JN214_RS21085	COG1357	PFAM Pentapeptide repeats (8 copies)
JN214_RS21100	COG2018	Roadblock/LC7 domain
JN214_RS21115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JN214_RS21130	COG0587	DNA-directed DNA polymerase activity
JN214_RS21135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN214_RS21135	COG1877	trehalose-phosphatase activity
JN214_RS21140	COG2030	dehydratase
JN214_RS21145	COG0406	alpha-ribazole phosphatase activity
JN214_RS21150	COG4221	oxidoreductase activity
JN214_RS21155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS21190	COG0519	Catalyzes the synthesis of GMP from XMP
JN214_RS21190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JN214_RS21280	COG2032	superoxide dismutase activity
JN214_RS21300	COG1309	transcriptional regulator
JN214_RS21310	COG0459	protein refolding
JN214_RS21325	COG0456	acetyltransferase
JN214_RS21330	COG1214	PFAM Peptidase M22, glycoprotease
JN214_RS21330	COG0456	acetyltransferase
JN214_RS21335	COG0802	atpase or kinase
JN214_RS21350	COG0076	glutamate decarboxylase activity
JN214_RS21370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN214_RS21390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS21420	COG4842	Belongs to the WXG100 family
JN214_RS21425	COG4842	Belongs to the WXG100 family
JN214_RS21435	COG1674	ftsk spoiiie
JN214_RS21445	COG1404	Belongs to the peptidase S8 family
JN214_RS21485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JN214_RS21490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JN214_RS21495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JN214_RS21500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JN214_RS21560	COG3794	PFAM blue (type 1) copper domain protein
JN214_RS21565	COG0723	plastoquinol--plastocyanin reductase activity
JN214_RS21585	COG1960	acyl-CoA dehydrogenase activity
JN214_RS21600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN214_RS21615	COG0028	Belongs to the TPP enzyme family
JN214_RS21620	COG0577	efflux transmembrane transporter activity
JN214_RS21620	COG1136	(ABC) transporter
JN214_RS21625	COG0577	efflux transmembrane transporter activity
JN214_RS21630	COG2226	methyltransferase
JN214_RS21640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN214_RS21660	COG0563	adenylate kinase activity
JN214_RS21670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS21705	COG4221	oxidoreductase activity
JN214_RS21725	COG0616	signal peptide processing
JN214_RS21730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS21745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JN214_RS21750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JN214_RS21775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JN214_RS21785	COG1403	HNH endonuclease
JN214_RS21790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN214_RS21800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JN214_RS21890	COG0535	radical SAM domain protein
JN214_RS21915	COG0483	inositol monophosphate 1-phosphatase activity
JN214_RS21925	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS21950	COG0049	tRNA binding
JN214_RS21960	COG1309	transcriptional regulator
JN214_RS21990	COG1960	acyl-CoA dehydrogenase activity
JN214_RS22030	COG0222	ribosome binding
JN214_RS22065	COG2318	DinB family
JN214_RS22080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS22085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS22115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JN214_RS22125	COG2030	dehydratase
JN214_RS22130	COG2030	dehydratase
JN214_RS22135	COG2030	dehydratase
JN214_RS22160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN214_RS22175	COG0243	molybdopterin cofactor binding
JN214_RS22185	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN214_RS22195	COG2226	methyltransferase
JN214_RS22200	COG0778	Nitroreductase
JN214_RS22205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS22210	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JN214_RS22215	COG1074	ATP-dependent DNA helicase activity
JN214_RS22255	COG3537	Alpha-1,2-mannosidase
JN214_RS22275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JN214_RS22310	COG2124	cytochrome p450
JN214_RS22320	COG1914	H( )-stimulated, divalent metal cation uptake system
JN214_RS22325	COG0243	molybdopterin cofactor binding
JN214_RS22345	COG2072	flavoprotein involved in K transport
JN214_RS22355	COG0659	secondary active sulfate transmembrane transporter activity
JN214_RS22365	COG0501	Belongs to the peptidase M48B family
JN214_RS22370	COG0142	geranyltranstransferase activity
JN214_RS22385	COG2226	methyltransferase
JN214_RS22390	COG4221	oxidoreductase activity
JN214_RS22415	COG4948	Mandelate Racemase Muconate Lactonizing
JN214_RS22420	COG1228	amidohydrolase
JN214_RS22445	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS22455	COG0667	Aldo Keto reductase
JN214_RS22470	COG4221	oxidoreductase activity
JN214_RS22525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN214_RS22530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JN214_RS22555	COG2894	cell division
JN214_RS22560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JN214_RS22570	COG0785	Cytochrome C biogenesis protein
JN214_RS22580	COG0406	alpha-ribazole phosphatase activity
JN214_RS22600	COG4948	Mandelate Racemase Muconate Lactonizing
JN214_RS22605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JN214_RS22615	COG1113	amino acid transport
JN214_RS22625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS22635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN214_RS22635	COG2755	lipolytic protein G-D-S-L family
JN214_RS22640	COG2755	lipolytic protein G-D-S-L family
JN214_RS22650	COG1366	Belongs to the anti-sigma-factor antagonist family
JN214_RS22715	COG2030	dehydratase
JN214_RS22785	COG0588	phosphoglycerate mutase activity
JN214_RS22795	COG0438	transferase activity, transferring glycosyl groups
JN214_RS22835	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JN214_RS22860	COG2733	membrane
JN214_RS22875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN214_RS22935	COG1505	serine-type exopeptidase activity
JN214_RS22945	COG1024	Enoyl-CoA hydratase
JN214_RS22955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN214_RS23000	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN214_RS23020	COG4221	oxidoreductase activity
JN214_RS23050	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS23060	COG0738	Major facilitator superfamily
JN214_RS23075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN214_RS23125	COG2032	superoxide dismutase activity
JN214_RS23140	COG0242	peptide deformylase activity
JN214_RS23170	COG3707	response regulator
JN214_RS23240	COG1088	dTDP-glucose 4,6-dehydratase activity
JN214_RS23245	COG2234	aminopeptidase activity
JN214_RS23250	COG2234	aminopeptidase activity
JN214_RS23290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN214_RS23290	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JN214_RS23310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN214_RS23325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JN214_RS23340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN214_RS23360	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS23365	COG1960	acyl-CoA dehydrogenase activity
JN214_RS23385	COG1252	NADH dehydrogenase
JN214_RS23395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN214_RS23415	COG0406	alpha-ribazole phosphatase activity
JN214_RS23425	COG1994	Peptidase M50
JN214_RS23495	COG0542	response to heat
JN214_RS23515	COG0789	Transcriptional regulator
JN214_RS23520	COG0484	heat shock protein binding
JN214_RS23525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JN214_RS23560	COG2814	Major facilitator Superfamily
JN214_RS23575	COG2181	nitrate reductase activity
JN214_RS23575	COG0247	lactate metabolic process
JN214_RS23605	COG2226	methyltransferase
JN214_RS23610	COG0477	Major facilitator Superfamily
JN214_RS23615	COG2175	clavaminate synthase activity
JN214_RS23620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JN214_RS23665	COG1376	ErfK ybiS ycfS ynhG family protein
JN214_RS23685	COG0246	Mannitol dehydrogenase
JN214_RS23690	COG1070	Carbohydrate kinase
JN214_RS23730	COG2130	NADP-dependent
JN214_RS23790	COG0778	Nitroreductase
JN214_RS23795	COG1368	sulfuric ester hydrolase activity
JN214_RS23815	COG1404	Belongs to the peptidase S8 family
JN214_RS23865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS23870	COG0254	rRNA binding
JN214_RS23885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JN214_RS23890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JN214_RS23895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JN214_RS23935	COG0346	lactoylglutathione lyase activity
JN214_RS23950	COG1960	acyl-CoA dehydrogenase activity
JN214_RS23960	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS23970	COG2223	nitrite transmembrane transporter activity
JN214_RS23985	COG1984	allophanate hydrolase subunit 2
JN214_RS24015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN214_RS24015	COG2146	nitrite reductase [NAD(P)H] activity
JN214_RS24040	COG1053	succinate dehydrogenase
JN214_RS24065	COG1960	acyl-CoA dehydrogenase activity
JN214_RS24070	COG0183	Belongs to the thiolase family
JN214_RS24075	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS24080	COG2030	dehydratase
JN214_RS24100	COG1472	Belongs to the glycosyl hydrolase 3 family
JN214_RS24115	COG4981	capsule polysaccharide biosynthetic process
JN214_RS24125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN214_RS24185	COG0028	Belongs to the TPP enzyme family
JN214_RS24190	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS24195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JN214_RS24255	COG0586	Pfam SNARE associated Golgi protein
JN214_RS24275	COG1309	transcriptional regulator
JN214_RS24285	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS24300	COG1024	Enoyl-CoA hydratase
JN214_RS24310	COG0657	acetylesterase activity
JN214_RS24320	COG2267	carboxylic ester hydrolase activity
JN214_RS24330	COG1228	amidohydrolase
JN214_RS24355	COG1024	Enoyl-CoA hydratase
JN214_RS24365	COG2199	diguanylate cyclase activity
JN214_RS24365	COG2203	Gaf domain
JN214_RS24370	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JN214_RS24395	COG2409	Drug exporters of the RND superfamily
JN214_RS24435	COG3590	peptidase
JN214_RS24440	COG0243	molybdopterin cofactor binding
JN214_RS24450	COG1376	ErfK ybiS ycfS ynhG family protein
JN214_RS24455	COG2814	Major facilitator Superfamily
JN214_RS24460	COG1937	Protein conserved in bacteria
JN214_RS24465	COG0129	dihydroxy-acid dehydratase activity
JN214_RS24480	COG4122	O-methyltransferase activity
JN214_RS24490	COG1472	Belongs to the glycosyl hydrolase 3 family
JN214_RS24505	COG2267	carboxylic ester hydrolase activity
JN214_RS24545	COG3619	membrane
JN214_RS24560	COG1714	RDD family
JN214_RS24575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN214_RS24600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS24605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN214_RS24615	COG1802	Transcriptional regulator
JN214_RS24645	COG0657	acetylesterase activity
JN214_RS24670	COG1063	alcohol dehydrogenase
JN214_RS24675	COG2124	cytochrome p450
JN214_RS24705	COG1960	acyl-CoA dehydrogenase activity
JN214_RS24710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS24755	COG0277	FAD linked oxidase domain protein
JN214_RS24775	COG1309	transcriptional regulator
JN214_RS24805	COG1960	acyl-CoA dehydrogenase activity
JN214_RS24810	COG2365	Tyrosine phosphatase family
JN214_RS24815	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS24820	COG1012	belongs to the aldehyde dehydrogenase family
JN214_RS24845	COG1741	Belongs to the pirin family
JN214_RS24850	COG0783	Belongs to the Dps family
JN214_RS24870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN214_RS24885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN214_RS24900	COG3585	molybdate ion transport
JN214_RS24905	COG0596	Alpha beta hydrolase
JN214_RS24925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS24960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN214_RS24970	COG3546	catalase activity
JN214_RS25005	COG1129	ABC transporter
JN214_RS25005	COG0842	Transport permease protein
JN214_RS25025	COG3281	Trehalose synthase
JN214_RS25035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN214_RS25055	COG0028	Belongs to the TPP enzyme family
JN214_RS25060	COG0583	DNA-binding transcription factor activity
JN214_RS25065	COG1376	ErfK ybiS ycfS ynhG family protein
JN214_RS25100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN214_RS25100	COG2755	lipolytic protein G-D-S-L family
JN214_RS25110	COG0028	Belongs to the TPP enzyme family
JN214_RS25115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS25120	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25125	COG2072	flavoprotein involved in K transport
JN214_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25140	COG3386	PFAM SMP-30 Gluconolaconase
JN214_RS25150	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS25160	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS25205	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS25220	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JN214_RS25240	COG2226	methyltransferase
JN214_RS25250	COG0300	oxidoreductase activity
JN214_RS25295	COG1063	alcohol dehydrogenase
JN214_RS25320	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25325	COG2072	flavoprotein involved in K transport
JN214_RS25350	COG0583	DNA-binding transcription factor activity
JN214_RS25370	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25375	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25390	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN214_RS25410	COG1309	transcriptional regulator
JN214_RS25420	COG1028	Short-chain dehydrogenase reductase Sdr
JN214_RS25425	COG0318	PFAM AMP-dependent synthetase and ligase
JN214_RS25450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN214_RS25475	COG1960	acyl-CoA dehydrogenase activity
JN214_RS25480	COG1309	transcriptional regulator
JN214_RS25505	COG3588	fructose-bisphosphate aldolase
JN214_RS25540	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN214_RS25545	COG4638	Rieske (2fe-2S)
JN214_RS25555	COG2197	response regulator
JN214_RS25560	COG4585	Histidine kinase
JN214_RS25575	COG1674	ftsk spoiiie
JN214_RS25640	COG1595	DNA-templated transcription, initiation
JN214_RS25660	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN214_RS25660	COG3409	Peptidoglycan-binding domain 1 protein
JN214_RS25675	COG1192	Involved in chromosome partitioning
JN214_RS25680	COG0357	Ribosomal RNA small subunit methyltransferase G
JN214_RS25690	COG0706	membrane insertase activity
JN214_RS25695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane