locus-tag	class	description
JN215_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN215_RS00010	COG0592	DNA-directed DNA polymerase activity
JN215_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JN215_RS00025	COG0187	DNA topoisomerase II activity
JN215_RS00030	COG1372	Participates in initiation and elongation during chromosome replication
JN215_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JN215_RS00065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JN215_RS00095	COG0515	serine threonine protein kinase
JN215_RS00120	COG1716	ATPase activity
JN215_RS00150	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS00180	COG1960	acyl-CoA dehydrogenase activity
JN215_RS00260	COG0495	leucyl-tRNA aminoacylation
JN215_RS00275	COG1126	abc transporter atp-binding protein
JN215_RS00280	COG0765	amino acid transport
JN215_RS00290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS00305	COG1309	transcriptional regulator
JN215_RS00310	COG0596	Alpha beta hydrolase
JN215_RS00310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN215_RS00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN215_RS00370	COG0360	Binds together with S18 to 16S ribosomal RNA
JN215_RS00460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN215_RS00510	COG1309	transcriptional regulator
JN215_RS00520	COG0494	nUDIX hydrolase
JN215_RS00535	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JN215_RS00540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN215_RS00545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS00550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JN215_RS00630	COG1309	transcriptional regulator
JN215_RS00645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS00650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS00720	COG1024	Enoyl-CoA hydratase
JN215_RS00725	COG1024	Enoyl-CoA hydratase
JN215_RS00730	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS00750	COG0183	Belongs to the thiolase family
JN215_RS00760	COG0183	Belongs to the thiolase family
JN215_RS00775	COG1233	COG1233 Phytoene dehydrogenase and related
JN215_RS00795	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS00810	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS00825	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
JN215_RS00840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS00845	COG1846	Transcriptional regulator
JN215_RS00870	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JN215_RS00870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS00900	COG4221	oxidoreductase activity
JN215_RS00930	COG2124	cytochrome p450
JN215_RS00935	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS00940	COG1233	COG1233 Phytoene dehydrogenase and related
JN215_RS00945	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS00980	COG1902	pentaerythritol trinitrate reductase activity
JN215_RS00980	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN215_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS00995	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS01020	COG2124	cytochrome p450
JN215_RS01025	COG1960	acyl-CoA dehydrogenase activity
JN215_RS01055	COG2910	NAD(P)H-binding
JN215_RS01060	COG2124	cytochrome p450
JN215_RS01065	COG1902	pentaerythritol trinitrate reductase activity
JN215_RS01065	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN215_RS01075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN215_RS01075	COG0574	Belongs to the PEP-utilizing enzyme family
JN215_RS01145	COG0574	Belongs to the PEP-utilizing enzyme family
JN215_RS01145	COG3848	Pyruvate phosphate dikinase
JN215_RS01150	COG0183	Belongs to the thiolase family
JN215_RS01155	COG1960	acyl-CoA dehydrogenase activity
JN215_RS01170	COG2826	transposase and inactivated derivatives, IS30 family
JN215_RS01200	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS01205	COG0277	FAD linked oxidase domain protein
JN215_RS01215	COG2267	carboxylic ester hydrolase activity
JN215_RS01220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS01230	COG1247	-acetyltransferase
JN215_RS01255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS01300	COG1309	transcriptional regulator
JN215_RS01360	COG0659	secondary active sulfate transmembrane transporter activity
JN215_RS01370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN215_RS01380	COG2124	cytochrome p450
JN215_RS01390	COG0714	Associated with various cellular activities
JN215_RS01410	COG0477	Major facilitator Superfamily
JN215_RS01430	COG0346	lactoylglutathione lyase activity
JN215_RS01470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS01490	COG4552	Acetyltransferase involved in intracellular survival and related
JN215_RS01495	COG1960	acyl-CoA dehydrogenase activity
JN215_RS01500	COG1309	transcriptional regulator
JN215_RS01515	COG5651	PPE family
JN215_RS01565	COG0702	epimerase
JN215_RS01580	COG0069	glutamate synthase activity
JN215_RS01580	COG0067	glutamate synthase
JN215_RS01580	COG0070	glutamate synthase
JN215_RS01600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JN215_RS01600	COG1796	DNA polymerase
JN215_RS01610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN215_RS01620	COG2072	flavoprotein involved in K transport
JN215_RS01660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN215_RS01680	COG1316	TRANSCRIPTIONal
JN215_RS01770	COG0561	phosphatase activity
JN215_RS01790	COG1216	Glycosyl transferase, family 2
JN215_RS01805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JN215_RS01815	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN215_RS01820	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JN215_RS01825	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS01830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN215_RS01830	COG3321	synthase
JN215_RS01830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN215_RS01835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN215_RS01850	COG1960	acyl-CoA dehydrogenase activity
JN215_RS01890	COG0640	Transcriptional regulator
JN215_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS01910	COG0277	FAD linked oxidase domain protein
JN215_RS01925	COG1403	HNH endonuclease
JN215_RS01960	COG0604	alcohol dehydrogenase
JN215_RS01980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN215_RS02000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN215_RS02045	COG0745	RESPONSE REGULATOR receiver
JN215_RS02050	COG2205	protein histidine kinase activity
JN215_RS02060	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JN215_RS02105	COG5416	Lipopolysaccharide assembly protein A domain
JN215_RS02120	COG1174	glycine betaine transport
JN215_RS02135	COG0287	Prephenate dehydrogenase
JN215_RS02145	COG0590	tRNA wobble adenosine to inosine editing
JN215_RS02170	COG1511	domain protein
JN215_RS02215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS02220	COG2301	Belongs to the HpcH HpaI aldolase family
JN215_RS02225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN215_RS02235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN215_RS02245	COG1396	sequence-specific DNA binding
JN215_RS02245	COG3800	Transcriptional regulator
JN215_RS02250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN215_RS02255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN215_RS02275	COG3804	dihydrodipicolinate reductase
JN215_RS02295	COG0596	Alpha beta hydrolase
JN215_RS02300	COG2124	cytochrome p450
JN215_RS02320	COG1793	dna ligase
JN215_RS02335	COG1335	isochorismatase
JN215_RS02375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN215_RS02400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN215_RS02410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS02425	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN215_RS02430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JN215_RS02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JN215_RS02455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JN215_RS02500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN215_RS02505	COG0121	glutamine amidotransferase
JN215_RS02515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN215_RS02530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN215_RS02535	COG1695	Transcriptional regulator
JN215_RS02560	COG0714	Associated with various cellular activities
JN215_RS02585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS02595	COG0693	protein deglycase activity
JN215_RS02600	COG2890	protein-(glutamine-N5) methyltransferase activity
JN215_RS02625	COG2172	sigma factor antagonist activity
JN215_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS02650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN215_RS02675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN215_RS02680	COG1408	metallophosphoesterase
JN215_RS02715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN215_RS02730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JN215_RS02740	COG0494	nUDIX hydrolase
JN215_RS02765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN215_RS02785	COG0601	transmembrane transport
JN215_RS02790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN215_RS02850	COG1111	helicase
JN215_RS02850	COG1205	dead DEAH box helicase
JN215_RS02875	COG0470	DNA polymerase III
JN215_RS02925	COG2027	D-alanyl-D-alanine carboxypeptidase
JN215_RS02935	COG0037	tRNA processing
JN215_RS02960	COG0657	acetylesterase activity
JN215_RS02970	COG1403	HNH endonuclease
JN215_RS02975	COG1063	alcohol dehydrogenase
JN215_RS02985	COG2267	carboxylic ester hydrolase activity
JN215_RS03000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN215_RS03005	COG0302	gtp cyclohydrolase
JN215_RS03010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JN215_RS03015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JN215_RS03040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN215_RS03120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JN215_RS03155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JN215_RS03165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN215_RS03170	COG1121	(ABC) transporter
JN215_RS03180	COG1609	Transcriptional regulator
JN215_RS03185	COG1309	transcriptional regulator
JN215_RS03190	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03240	COG0436	Aminotransferase
JN215_RS03245	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03250	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03255	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03260	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS03265	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03280	COG0183	Belongs to the thiolase family
JN215_RS03310	COG1024	Enoyl-CoA hydratase
JN215_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS03340	COG0183	Belongs to the thiolase family
JN215_RS03345	COG2124	cytochrome p450
JN215_RS03350	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03355	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03360	COG2030	dehydratase
JN215_RS03380	COG2030	dehydratase
JN215_RS03385	COG1053	succinate dehydrogenase
JN215_RS03390	COG3971	2-oxopent-4-enoate hydratase activity
JN215_RS03395	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JN215_RS03400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN215_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS03430	COG4638	Rieske (2fe-2S)
JN215_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS03470	COG2124	cytochrome p450
JN215_RS03490	COG3001	Fructosamine kinase
JN215_RS03500	COG0028	Belongs to the TPP enzyme family
JN215_RS03515	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS03520	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03525	COG1960	acyl-CoA dehydrogenase activity
JN215_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS03540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS03545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS03570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN215_RS03605	COG1024	Enoyl-CoA hydratase
JN215_RS03620	COG1316	TRANSCRIPTIONal
JN215_RS03690	COG0745	RESPONSE REGULATOR receiver
JN215_RS03695	COG2205	protein histidine kinase activity
JN215_RS03725	COG2124	cytochrome p450
JN215_RS03730	COG0300	oxidoreductase activity
JN215_RS03745	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS03765	COG0667	Aldo Keto reductase
JN215_RS03800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN215_RS03820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JN215_RS03830	COG0477	Major facilitator Superfamily
JN215_RS03835	COG0477	Major facilitator Superfamily
JN215_RS03850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN215_RS03860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN215_RS03865	COG0047	phosphoribosylformylglycinamidine synthase activity
JN215_RS03875	COG0204	Acyl-transferase
JN215_RS03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN215_RS03895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN215_RS03935	COG1017	nitric oxide dioxygenase activity
JN215_RS03935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN215_RS03945	COG2837	iron assimilation
JN215_RS03995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JN215_RS04045	COG0745	RESPONSE REGULATOR receiver
JN215_RS04070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN215_RS04110	COG0640	Transcriptional regulator
JN215_RS04115	COG0590	tRNA wobble adenosine to inosine editing
JN215_RS04165	COG4974	Belongs to the 'phage' integrase family
JN215_RS04180	COG1609	Transcriptional regulator
JN215_RS04190	COG1309	transcriptional regulator
JN215_RS04195	COG0596	Alpha beta hydrolase
JN215_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS04240	COG2124	cytochrome p450
JN215_RS04245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN215_RS04250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS04270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN215_RS04270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN215_RS04275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JN215_RS04280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS04285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS04320	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04325	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04335	COG2267	carboxylic ester hydrolase activity
JN215_RS04340	COG3479	Phenolic acid decarboxylase
JN215_RS04345	COG0183	Belongs to the thiolase family
JN215_RS04350	COG1703	isobutyryl-CoA mutase activity
JN215_RS04355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN215_RS04365	COG4585	Histidine kinase
JN215_RS04375	COG0504	CTP synthase activity
JN215_RS04380	COG1053	succinate dehydrogenase
JN215_RS04390	COG2267	carboxylic ester hydrolase activity
JN215_RS04395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS04400	COG3384	dioxygenase
JN215_RS04405	COG1053	succinate dehydrogenase
JN215_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS04430	COG2132	Multicopper oxidase
JN215_RS04445	COG2197	response regulator
JN215_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS04505	COG1024	Enoyl-CoA hydratase
JN215_RS04510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS04535	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04550	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JN215_RS04570	COG4638	Rieske (2fe-2S)
JN215_RS04590	COG1024	Enoyl-CoA hydratase
JN215_RS04595	COG0183	Belongs to the thiolase family
JN215_RS04600	COG1309	transcriptional regulator
JN215_RS04630	COG2124	cytochrome p450
JN215_RS04635	COG2084	Dehydrogenase
JN215_RS04675	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JN215_RS04725	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JN215_RS04725	COG0778	Nitroreductase
JN215_RS04730	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04735	COG1960	acyl-CoA dehydrogenase activity
JN215_RS04775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS04780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS04785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS04810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN215_RS04880	COG1024	Enoyl-CoA hydratase
JN215_RS04895	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS04920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS04940	COG0183	Belongs to the thiolase family
JN215_RS04945	COG1024	Enoyl-CoA hydratase
JN215_RS04945	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN215_RS04950	COG2813	Specifically methylates the guanine in position
JN215_RS04970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS05000	COG1061	Type III restriction enzyme res subunit
JN215_RS05040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN215_RS05045	COG3304	Inner membrane component domain
JN215_RS05050	COG1278	Cold shock
JN215_RS05060	COG0435	Glutathione S-transferase
JN215_RS05075	COG2814	Major facilitator Superfamily
JN215_RS05115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JN215_RS05140	COG0259	pyridoxamine-phosphate oxidase activity
JN215_RS05265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS05305	COG0581	inorganic phosphate transmembrane transporter activity
JN215_RS05330	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS05365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN215_RS05395	COG4942	peptidase
JN215_RS05435	COG0138	bifunctional purine biosynthesis protein purh
JN215_RS05455	COG0656	L-ascorbic acid biosynthetic process
JN215_RS05465	COG1024	Enoyl-CoA hydratase
JN215_RS05480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN215_RS05485	COG1960	acyl-CoA dehydrogenase activity
JN215_RS05510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN215_RS05515	COG0521	Mo-molybdopterin cofactor biosynthetic process
JN215_RS05515	COG0315	cyclic pyranopterin monophosphate synthase activity
JN215_RS05520	COG1970	mechanosensitive ion channel activity
JN215_RS05535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN215_RS05540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JN215_RS05575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS05615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN215_RS05620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JN215_RS05625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN215_RS05625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN215_RS05660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN215_RS05670	COG1252	NADH dehydrogenase
JN215_RS05745	COG0297	glycogen (starch) synthase activity
JN215_RS05760	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JN215_RS05810	COG0084	hydrolase, TatD family'
JN215_RS05825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JN215_RS05830	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS05835	COG0193	aminoacyl-tRNA hydrolase activity
JN215_RS05840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JN215_RS05885	COG1309	transcriptional regulator
JN215_RS05900	COG3956	TIGRFAM MazG family protein
JN215_RS05945	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JN215_RS05950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JN215_RS05970	COG2205	protein histidine kinase activity
JN215_RS05975	COG0745	RESPONSE REGULATOR receiver
JN215_RS06025	COG3391	amine dehydrogenase activity
JN215_RS06030	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS06040	COG0121	glutamine amidotransferase
JN215_RS06085	COG1024	Enoyl-CoA hydratase
JN215_RS06095	COG0183	Belongs to the thiolase family
JN215_RS06100	COG2755	lipolytic protein G-D-S-L family
JN215_RS06105	COG0657	acetylesterase activity
JN215_RS06145	COG1331	Highly conserved protein containing a thioredoxin domain
JN215_RS06160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JN215_RS06170	COG0572	uridine kinase
JN215_RS06185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JN215_RS06235	COG2272	Belongs to the type-B carboxylesterase lipase family
JN215_RS06250	COG1570	exodeoxyribonuclease VII activity
JN215_RS06260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JN215_RS06270	COG0012	GTP binding
JN215_RS06340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JN215_RS06370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN215_RS06370	COG0574	Belongs to the PEP-utilizing enzyme family
JN215_RS06400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JN215_RS06405	COG0702	epimerase
JN215_RS06415	COG1309	transcriptional regulator
JN215_RS06425	COG1960	acyl-CoA dehydrogenase activity
JN215_RS06430	COG1960	acyl-CoA dehydrogenase activity
JN215_RS06435	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS06445	COG0714	Associated with various cellular activities
JN215_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS06465	COG2124	cytochrome p450
JN215_RS06470	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS06495	COG0183	Belongs to the thiolase family
JN215_RS06500	COG1024	Enoyl-CoA hydratase
JN215_RS06510	COG1755	Isoprenylcysteine carboxyl methyltransferase
JN215_RS06520	COG0702	epimerase
JN215_RS06530	COG0702	epimerase
JN215_RS06535	COG1024	Enoyl-CoA hydratase
JN215_RS06540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS06550	COG2409	Drug exporters of the RND superfamily
JN215_RS06560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JN215_RS06575	COG3467	pyridoxamine 5'-phosphate
JN215_RS06635	COG1140	nitrate reductase beta subunit
JN215_RS06650	COG1217	gtp-binding protein TYPA
JN215_RS06665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN215_RS06675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JN215_RS06690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN215_RS06700	COG0531	amino acid
JN215_RS06705	COG3321	synthase
JN215_RS06705	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS06705	COG0604	alcohol dehydrogenase
JN215_RS06720	COG0529	Catalyzes the synthesis of activated sulfate
JN215_RS06725	COG2046	Belongs to the sulfate adenylyltransferase family
JN215_RS06740	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS06755	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS06765	COG1309	transcriptional regulator
JN215_RS06790	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS06800	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS06805	COG0477	Major facilitator Superfamily
JN215_RS06835	COG1611	Belongs to the LOG family
JN215_RS06840	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS06850	COG0463	Glycosyl transferase, family 2
JN215_RS06860	COG0519	Catalyzes the synthesis of GMP from XMP
JN215_RS06875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JN215_RS06885	COG3559	Exporter of polyketide antibiotics
JN215_RS06890	COG1131	(ABC) transporter
JN215_RS06895	COG1309	transcriptional regulator
JN215_RS06910	COG5662	AntiSigma factor
JN215_RS06915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN215_RS06920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN215_RS06940	COG2239	Acts as a magnesium transporter
JN215_RS06980	COG0598	Magnesium transport protein CorA
JN215_RS06985	COG0039	L-malate dehydrogenase activity
JN215_RS07055	COG0277	FAD linked oxidase domain protein
JN215_RS07070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS07220	COG3631	Ketosteroid isomerase-related protein
JN215_RS07225	COG0494	nUDIX hydrolase
JN215_RS07250	COG0018	arginyl-trna synthetase
JN215_RS07255	COG0019	diaminopimelate decarboxylase activity
JN215_RS07260	COG0460	homoserine dehydrogenase
JN215_RS07270	COG0083	homoserine kinase activity
JN215_RS07290	COG2890	protein-(glutamine-N5) methyltransferase activity
JN215_RS07310	COG0356	it plays a direct role in the translocation of protons across the membrane
JN215_RS07315	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN215_RS07325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JN215_RS07325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN215_RS07360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JN215_RS07380	COG5651	PPE family
JN215_RS07405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JN215_RS07425	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JN215_RS07450	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN215_RS07460	COG0058	SHG alpha-glucan phosphorylase activity
JN215_RS07470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JN215_RS07500	COG1234	tRNA 3'-trailer cleavage
JN215_RS07505	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JN215_RS07510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JN215_RS07535	COG3011	Protein conserved in bacteria
JN215_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS07570	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07580	COG0183	Belongs to the thiolase family
JN215_RS07585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS07590	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07595	COG1802	Transcriptional regulator
JN215_RS07600	COG4977	sequence-specific DNA binding
JN215_RS07630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN215_RS07640	COG1024	Enoyl-CoA hydratase
JN215_RS07645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN215_RS07665	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS07670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN215_RS07680	COG1024	Enoyl-CoA hydratase
JN215_RS07705	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07715	COG0183	Belongs to the thiolase family
JN215_RS07765	COG4638	Rieske (2fe-2S)
JN215_RS07775	COG2072	flavoprotein involved in K transport
JN215_RS07795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN215_RS07810	COG1309	transcriptional regulator
JN215_RS07830	COG2124	cytochrome p450
JN215_RS07835	COG0657	acetylesterase activity
JN215_RS07840	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07845	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07870	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07875	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07880	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07885	COG1960	acyl-CoA dehydrogenase activity
JN215_RS07915	COG2124	cytochrome p450
JN215_RS07975	COG3757	hydrolase, family 25
JN215_RS07980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN215_RS07980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JN215_RS07980	COG3321	synthase
JN215_RS07985	COG0736	holo-[acyl-carrier-protein] synthase activity
JN215_RS08030	COG2409	Drug exporters of the RND superfamily
JN215_RS08035	COG0697	spore germination
JN215_RS08040	COG1376	ErfK ybiS ycfS ynhG family protein
JN215_RS08060	COG0433	COG0433 Predicted ATPase
JN215_RS08065	COG0300	oxidoreductase activity
JN215_RS08085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN215_RS08095	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08100	COG2030	dehydratase
JN215_RS08120	COG0508	dehydrogenase complex catalyzes the overall conversion of
JN215_RS08145	COG0657	acetylesterase activity
JN215_RS08160	COG2937	Belongs to the GPAT DAPAT family
JN215_RS08175	COG0629	single-stranded DNA binding
JN215_RS08185	COG2902	Dehydrogenase
JN215_RS08205	COG0366	Alpha amylase catalytic
JN215_RS08210	COG2346	COG2346, Truncated hemoglobins
JN215_RS08235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JN215_RS08240	COG0698	ribose 5-phosphate isomerase
JN215_RS08255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN215_RS08275	COG0740	serine-type endopeptidase activity
JN215_RS08280	COG0740	serine-type endopeptidase activity
JN215_RS08285	COG2040	homocysteine
JN215_RS08300	COG0674	pyruvate-flavodoxin oxidoreductase activity
JN215_RS08300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JN215_RS08305	COG1013	pyruvate-flavodoxin oxidoreductase activity
JN215_RS08315	COG1388	LysM domain
JN215_RS08320	COG3268	Saccharopine dehydrogenase
JN215_RS08325	COG0525	valine-tRNA ligase activity
JN215_RS08330	COG0285	dihydrofolate synthase activity
JN215_RS08340	COG0105	UTP biosynthetic process
JN215_RS08345	COG1530	ribonuclease E activity
JN215_RS08360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JN215_RS08390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JN215_RS08390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN215_RS08395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN215_RS08400	COG5002	protein histidine kinase activity
JN215_RS08405	COG0668	transmembrane transport
JN215_RS08410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN215_RS08415	COG0542	response to heat
JN215_RS08425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JN215_RS08430	COG0799	negative regulation of ribosome biogenesis
JN215_RS08440	COG2755	lipolytic protein G-D-S-L family
JN215_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS08470	COG5651	PPE family
JN215_RS08475	COG2409	Drug exporters of the RND superfamily
JN215_RS08495	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08500	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08505	COG1555	photosystem II stabilization
JN215_RS08505	COG1596	polysaccharide export
JN215_RS08535	COG1305	Transglutaminase-like
JN215_RS08540	COG1733	regulation of RNA biosynthetic process
JN215_RS08555	COG1234	tRNA 3'-trailer cleavage
JN215_RS08560	COG0517	IMP dehydrogenase activity
JN215_RS08570	COG0481	GTPase activity
JN215_RS08585	COG3387	PFAM Glycoside hydrolase 15-related
JN215_RS08595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JN215_RS08600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JN215_RS08605	COG4208	sulfate ABC transporter
JN215_RS08610	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN215_RS08620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN215_RS08640	COG1169	isochorismate synthase
JN215_RS08650	COG2072	flavoprotein involved in K transport
JN215_RS08705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN215_RS08720	COG2124	cytochrome p450
JN215_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS08765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN215_RS08780	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS08800	COG1063	alcohol dehydrogenase
JN215_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS08855	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08870	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS08915	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08925	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08930	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08935	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN215_RS08970	COG1024	Enoyl-CoA hydratase
JN215_RS08980	COG1960	acyl-CoA dehydrogenase activity
JN215_RS08985	COG1024	Enoyl-CoA hydratase
JN215_RS08995	COG1024	Enoyl-CoA hydratase
JN215_RS09000	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS09005	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS09035	COG1024	Enoyl-CoA hydratase
JN215_RS09050	COG1960	acyl-CoA dehydrogenase activity
JN215_RS09065	COG1024	Enoyl-CoA hydratase
JN215_RS09080	COG2124	cytochrome p450
JN215_RS09135	COG4948	Mandelate Racemase Muconate Lactonizing
JN215_RS09145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN215_RS09180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN215_RS09185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN215_RS09260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JN215_RS09275	COG1309	transcriptional regulator
JN215_RS09295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JN215_RS09300	COG1021	2,3-dihydroxybenzoate-AMP ligase
JN215_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN215_RS09320	COG3321	synthase
JN215_RS09320	COG0604	alcohol dehydrogenase
JN215_RS09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN215_RS09335	COG3486	L-lysine 6-monooxygenase (NADPH) activity
JN215_RS09355	COG1595	DNA-templated transcription, initiation
JN215_RS09370	COG1420	regulation of RNA biosynthetic process
JN215_RS09375	COG0484	heat shock protein binding
JN215_RS09410	COG1982	Orn Lys Arg decarboxylase major
JN215_RS09420	COG1381	Involved in DNA repair and RecF pathway recombination
JN215_RS09445	COG0423	glycine-tRNA ligase activity
JN215_RS09490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS09495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS09505	COG1045	serine acetyltransferase
JN215_RS09515	COG2855	membrane
JN215_RS09525	COG4424	Sulfotransferase
JN215_RS09535	COG0243	molybdopterin cofactor binding
JN215_RS09550	COG1716	ATPase activity
JN215_RS09550	COG0842	Transport permease protein
JN215_RS09550	COG1131	(ABC) transporter
JN215_RS09575	COG0531	amino acid
JN215_RS09590	COG1175	transmembrane transport
JN215_RS09665	COG2267	carboxylic ester hydrolase activity
JN215_RS09695	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS09720	COG2172	sigma factor antagonist activity
JN215_RS09720	COG2208	phosphoserine phosphatase activity
JN215_RS09720	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS09740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS09745	COG2226	methyltransferase
JN215_RS09825	COG2132	Multicopper oxidase
JN215_RS09850	COG0596	Alpha beta hydrolase
JN215_RS09865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN215_RS09880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS09900	COG2124	cytochrome p450
JN215_RS09905	COG2267	carboxylic ester hydrolase activity
JN215_RS09920	COG0798	PFAM Bile acid sodium symporter
JN215_RS09935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS09945	COG2124	cytochrome p450
JN215_RS09955	COG0438	transferase activity, transferring glycosyl groups
JN215_RS09970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN215_RS09985	COG0657	acetylesterase activity
JN215_RS09990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN215_RS10005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN215_RS10025	COG1309	transcriptional regulator
JN215_RS10090	COG1487	ribonuclease activity
JN215_RS10120	COG1960	acyl-CoA dehydrogenase activity
JN215_RS10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN215_RS10140	COG2072	flavoprotein involved in K transport
JN215_RS10245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS10265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN215_RS10400	COG0596	Alpha beta hydrolase
JN215_RS10495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN215_RS10510	COG2226	methyltransferase
JN215_RS10520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN215_RS10540	COG2223	nitrite transmembrane transporter activity
JN215_RS10545	COG2323	membrane
JN215_RS10570	COG3391	amine dehydrogenase activity
JN215_RS10670	COG0321	lipoyl(octanoyl) transferase activity
JN215_RS10705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN215_RS10715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN215_RS10720	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JN215_RS10725	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN215_RS10755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN215_RS10765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN215_RS10800	COG1845	cytochrome c oxidase, subunit III
JN215_RS10830	COG1022	Amp-dependent synthetase and ligase
JN215_RS10845	COG0003	Pfam Anion-transporting ATPase
JN215_RS10875	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JN215_RS10895	COG0142	geranyltranstransferase activity
JN215_RS10935	COG0768	penicillin binding
JN215_RS10960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JN215_RS10975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN215_RS10990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN215_RS11035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN215_RS11045	COG0167	dihydroorotate dehydrogenase activity
JN215_RS11080	COG1218	3'(2'),5'-bisphosphate nucleotidase
JN215_RS11085	COG0215	cysteine-tRNA ligase activity
JN215_RS11115	COG3321	synthase
JN215_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS11115	COG0604	alcohol dehydrogenase
JN215_RS11120	COG2124	cytochrome p450
JN215_RS11135	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS11200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS11210	COG1309	transcriptional regulator
JN215_RS11285	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JN215_RS11305	COG2378	regulation of single-species biofilm formation
JN215_RS11355	COG0300	oxidoreductase activity
JN215_RS11400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN215_RS11435	COG0412	Dienelactone hydrolase
JN215_RS11470	COG0604	alcohol dehydrogenase
JN215_RS11470	COG3321	synthase
JN215_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS11510	COG0714	Associated with various cellular activities
JN215_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS11570	COG2272	Belongs to the type-B carboxylesterase lipase family
JN215_RS11580	COG3265	gluconokinase activity
JN215_RS11590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS11615	COG1335	isochorismatase
JN215_RS11630	COG1595	DNA-templated transcription, initiation
JN215_RS11640	COG1175	transmembrane transport
JN215_RS11645	COG0395	ABC-type sugar transport system, permease component
JN215_RS11650	COG3842	ATPase activity
JN215_RS11655	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN215_RS11680	COG2837	iron assimilation
JN215_RS11690	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JN215_RS11720	COG0667	Aldo Keto reductase
JN215_RS11730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN215_RS11750	COG1960	acyl-CoA dehydrogenase activity
JN215_RS11800	COG0523	cobalamin synthesis protein
JN215_RS11805	COG1946	Acyl-CoA thioesterase
JN215_RS11840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS11860	COG1595	DNA-templated transcription, initiation
JN215_RS11935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN215_RS11950	COG0583	DNA-binding transcription factor activity
JN215_RS11980	COG0545	Peptidyl-prolyl cis-trans isomerase
JN215_RS11985	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN215_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS12010	COG2301	Belongs to the HpcH HpaI aldolase family
JN215_RS12020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN215_RS12035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS12040	COG1643	Atp-dependent helicase
JN215_RS12050	COG1024	Enoyl-CoA hydratase
JN215_RS12070	COG1063	alcohol dehydrogenase
JN215_RS12120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN215_RS12120	COG0723	plastoquinol--plastocyanin reductase activity
JN215_RS12130	COG1376	ErfK ybiS ycfS ynhG family protein
JN215_RS12145	COG3757	hydrolase, family 25
JN215_RS12150	COG0438	transferase activity, transferring glycosyl groups
JN215_RS12155	COG2226	methyltransferase
JN215_RS12185	COG3391	amine dehydrogenase activity
JN215_RS12200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS12245	COG4977	sequence-specific DNA binding
JN215_RS12255	COG1733	regulation of RNA biosynthetic process
JN215_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS12280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN215_RS12285	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS12315	COG0640	Transcriptional regulator
JN215_RS12335	COG1233	COG1233 Phytoene dehydrogenase and related
JN215_RS12345	COG1942	4-Oxalocrotonate Tautomerase
JN215_RS12375	COG1950	PFAM Membrane protein of
JN215_RS12380	COG1403	HNH endonuclease
JN215_RS12390	COG2814	Major facilitator Superfamily
JN215_RS12395	COG1058	Belongs to the CinA family
JN215_RS12395	COG1546	Belongs to the CinA family
JN215_RS12420	COG1063	alcohol dehydrogenase
JN215_RS12430	COG2070	2-Nitropropane dioxygenase
JN215_RS12470	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN215_RS12515	COG0174	glutamine synthetase
JN215_RS12525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN215_RS12535	COG2193	ferroxidase activity
JN215_RS12545	COG1024	Enoyl-CoA hydratase
JN215_RS12570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN215_RS12630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS12635	COG1968	undecaprenyl-diphosphatase activity
JN215_RS12640	COG4221	oxidoreductase activity
JN215_RS12700	COG1252	NADH dehydrogenase
JN215_RS12720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JN215_RS12735	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS12740	COG1960	acyl-CoA dehydrogenase activity
JN215_RS12745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN215_RS12750	COG1253	flavin adenine dinucleotide binding
JN215_RS12755	COG1253	flavin adenine dinucleotide binding
JN215_RS12850	COG1053	succinate dehydrogenase
JN215_RS12850	COG3976	FMN-binding domain protein
JN215_RS12890	COG5651	PPE family
JN215_RS12935	COG1404	Belongs to the peptidase S8 family
JN215_RS12965	COG5651	PPE family
JN215_RS12975	COG5651	PPE family
JN215_RS12980	COG0657	acetylesterase activity
JN215_RS12985	COG5651	PPE family
JN215_RS13025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN215_RS13050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS13070	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS13075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN215_RS13080	COG0022	dehydrogenase e1 component
JN215_RS13090	COG1024	Enoyl-CoA hydratase
JN215_RS13095	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS13100	COG4638	Rieske (2fe-2S)
JN215_RS13105	COG1053	succinate dehydrogenase
JN215_RS13140	COG2813	Specifically methylates the guanine in position
JN215_RS13205	COG4221	oxidoreductase activity
JN215_RS13235	COG4221	oxidoreductase activity
JN215_RS13240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS13245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JN215_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS13295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS13315	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS13345	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS13350	COG2072	flavoprotein involved in K transport
JN215_RS13370	COG2030	dehydratase
JN215_RS13375	COG1960	acyl-CoA dehydrogenase activity
JN215_RS13380	COG1960	acyl-CoA dehydrogenase activity
JN215_RS13390	COG0842	Transport permease protein
JN215_RS13390	COG1131	(ABC) transporter
JN215_RS13390	COG1716	ATPase activity
JN215_RS13395	COG0657	acetylesterase activity
JN215_RS13405	COG0243	molybdopterin cofactor binding
JN215_RS13425	COG2267	carboxylic ester hydrolase activity
JN215_RS13450	COG2072	flavoprotein involved in K transport
JN215_RS13465	COG0346	lactoylglutathione lyase activity
JN215_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS13505	COG2072	flavoprotein involved in K transport
JN215_RS13510	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS13515	COG1960	acyl-CoA dehydrogenase activity
JN215_RS13535	COG0657	acetylesterase activity
JN215_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS13565	COG1053	succinate dehydrogenase
JN215_RS13630	COG2271	Major facilitator Superfamily
JN215_RS13635	COG0189	ligase activity
JN215_RS13635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN215_RS13665	COG1305	Transglutaminase-like
JN215_RS13675	COG1278	Cold shock
JN215_RS13710	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS13720	COG1960	acyl-CoA dehydrogenase activity
JN215_RS13735	COG0574	Belongs to the PEP-utilizing enzyme family
JN215_RS13735	COG3848	Pyruvate phosphate dikinase
JN215_RS13750	COG1960	acyl-CoA dehydrogenase activity
JN215_RS13775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS13810	COG3384	dioxygenase
JN215_RS13865	COG1024	Enoyl-CoA hydratase
JN215_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS13980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS13990	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS14000	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14005	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14015	COG3971	2-oxopent-4-enoate hydratase activity
JN215_RS14055	COG1024	Enoyl-CoA hydratase
JN215_RS14060	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS14075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14110	COG2826	transposase and inactivated derivatives, IS30 family
JN215_RS14130	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14155	COG1309	transcriptional regulator
JN215_RS14165	COG0006	proline dipeptidase activity
JN215_RS14215	COG1309	transcriptional regulator
JN215_RS14295	COG1024	Enoyl-CoA hydratase
JN215_RS14300	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14320	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14325	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14330	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14430	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS14440	COG1845	cytochrome c oxidase, subunit III
JN215_RS14465	COG0183	Belongs to the thiolase family
JN215_RS14480	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14485	COG0427	acetyl-CoA hydrolase
JN215_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14510	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS14515	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14525	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14550	COG1024	Enoyl-CoA hydratase
JN215_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14570	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14575	COG1960	acyl-CoA dehydrogenase activity
JN215_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS14630	COG2186	Transcriptional regulator
JN215_RS14635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS14655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN215_RS14680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS14685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS14690	COG1309	transcriptional regulator
JN215_RS14725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN215_RS14770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN215_RS14780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JN215_RS14805	COG0494	nUDIX hydrolase
JN215_RS14830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JN215_RS14845	COG0647	UMP catabolic process
JN215_RS14860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JN215_RS14865	COG2094	Belongs to the DNA glycosylase MPG family
JN215_RS14875	COG1131	(ABC) transporter
JN215_RS14890	COG1309	transcriptional regulator
JN215_RS14895	COG2835	tetraacyldisaccharide 4'-kinase activity
JN215_RS14925	COG0300	oxidoreductase activity
JN215_RS14930	COG4948	Mandelate Racemase Muconate Lactonizing
JN215_RS14935	COG3707	response regulator
JN215_RS14940	COG0488	(ABC) transporter
JN215_RS14955	COG3321	synthase
JN215_RS14955	COG0604	alcohol dehydrogenase
JN215_RS14955	COG0604	alcohol dehydrogenase
JN215_RS14955	COG3321	synthase
JN215_RS14960	COG3321	synthase
JN215_RS14960	COG0604	alcohol dehydrogenase
JN215_RS14965	COG0604	alcohol dehydrogenase
JN215_RS14965	COG3321	synthase
JN215_RS14975	COG0165	Argininosuccinate lyase
JN215_RS14990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JN215_RS15005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JN215_RS15010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JN215_RS15015	COG0072	phenylalanine-tRNA ligase activity
JN215_RS15015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN215_RS15020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JN215_RS15050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JN215_RS15075	COG1309	transcriptional regulator
JN215_RS15085	COG2890	protein-(glutamine-N5) methyltransferase activity
JN215_RS15120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN215_RS15150	COG1131	(ABC) transporter
JN215_RS15150	COG0842	Transport permease protein
JN215_RS15150	COG1716	ATPase activity
JN215_RS15165	COG2201	protein-glutamate methylesterase activity
JN215_RS15180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN215_RS15190	COG0237	dephospho-CoA kinase activity
JN215_RS15190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JN215_RS15305	COG1271	oxidase subunit
JN215_RS15310	COG1294	oxidase, subunit
JN215_RS15315	COG4988	ABC transporter
JN215_RS15320	COG1132	(ABC) transporter
JN215_RS15335	COG1946	Acyl-CoA thioesterase
JN215_RS15375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN215_RS15385	COG0387	Pfam Sodium calcium exchanger
JN215_RS15390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JN215_RS15400	COG0483	inositol monophosphate 1-phosphatase activity
JN215_RS15410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN215_RS15415	COG0131	Imidazoleglycerol-phosphate dehydratase
JN215_RS15425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN215_RS15435	COG0157	Belongs to the NadC ModD family
JN215_RS15495	COG5002	protein histidine kinase activity
JN215_RS15500	COG0668	transmembrane transport
JN215_RS15525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN215_RS15535	COG3883	PFAM NLP P60 protein
JN215_RS15535	COG0791	NLP P60 protein
JN215_RS15575	COG0671	phosphoesterase, PA-phosphatase related
JN215_RS15630	COG0300	oxidoreductase activity
JN215_RS15640	COG2346	COG2346, Truncated hemoglobins
JN215_RS15660	COG0252	asparaginase activity
JN215_RS15670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JN215_RS15680	COG2070	2-Nitropropane dioxygenase
JN215_RS15745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN215_RS15745	COG2755	lipolytic protein G-D-S-L family
JN215_RS15775	COG2226	methyltransferase
JN215_RS15790	COG4221	oxidoreductase activity
JN215_RS15840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN215_RS15890	COG2205	protein histidine kinase activity
JN215_RS15895	COG0745	RESPONSE REGULATOR receiver
JN215_RS15930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JN215_RS15935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JN215_RS15950	COG2304	oxidoreductase activity
JN215_RS15960	COG0714	Associated with various cellular activities
JN215_RS15970	COG0791	NLP P60 protein
JN215_RS15970	COG3883	PFAM NLP P60 protein
JN215_RS15980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JN215_RS15985	COG1309	transcriptional regulator
JN215_RS15995	COG0488	(ABC) transporter
JN215_RS16005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN215_RS16010	COG1960	acyl-CoA dehydrogenase activity
JN215_RS16035	COG0251	oxidation-reduction process
JN215_RS16050	COG0183	Belongs to the thiolase family
JN215_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS16130	COG0657	acetylesterase activity
JN215_RS16185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN215_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS16225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN215_RS16250	COG2151	metal-sulfur cluster biosynthetic enzyme
JN215_RS16255	COG0822	iron-sulfur transferase activity
JN215_RS16265	COG0396	ATPase activity
JN215_RS16325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JN215_RS16350	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN215_RS16355	COG0667	Aldo Keto reductase
JN215_RS16360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JN215_RS16420	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS16425	COG0657	acetylesterase activity
JN215_RS16450	COG1660	Displays ATPase and GTPase activities
JN215_RS16455	COG0322	excinuclease ABC activity
JN215_RS16480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN215_RS16560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN215_RS16620	COG0657	acetylesterase activity
JN215_RS16650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JN215_RS16675	COG0505	Belongs to the CarA family
JN215_RS16695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JN215_RS16705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JN215_RS16735	COG2188	Transcriptional regulator
JN215_RS16765	COG0006	proline dipeptidase activity
JN215_RS16780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JN215_RS16805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN215_RS16810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JN215_RS16815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JN215_RS16825	COG0432	Pfam Uncharacterised protein family UPF0047
JN215_RS16890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JN215_RS16910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN215_RS16915	COG0235	Class ii aldolase
JN215_RS16920	COG1396	sequence-specific DNA binding
JN215_RS16955	COG1403	HNH endonuclease
JN215_RS16990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN215_RS17005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN215_RS17040	COG1914	H( )-stimulated, divalent metal cation uptake system
JN215_RS17050	COG5651	PPE family
JN215_RS17080	COG3344	reverse transcriptase
JN215_RS17085	COG3415	Transposase
JN215_RS17085	COG2801	Transposase and inactivated derivatives
JN215_RS17100	COG2239	Acts as a magnesium transporter
JN215_RS17200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JN215_RS17210	COG0124	histidyl-tRNA synthetase
JN215_RS17215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN215_RS17230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN215_RS17235	COG0747	negative chemotaxis
JN215_RS17240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JN215_RS17260	COG1022	Amp-dependent synthetase and ligase
JN215_RS17260	COG3320	Male sterility
JN215_RS17310	COG3766	membrane
JN215_RS17330	COG1946	Acyl-CoA thioesterase
JN215_RS17355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JN215_RS17385	COG0667	Aldo Keto reductase
JN215_RS17390	COG4762	Protein conserved in bacteria
JN215_RS17405	COG2070	2-Nitropropane dioxygenase
JN215_RS17445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JN215_RS17455	COG3485	protocatechuate 3,4-dioxygenase
JN215_RS17495	COG1414	Transcriptional regulator
JN215_RS17505	COG1309	transcriptional regulator
JN215_RS17510	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS17515	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN215_RS17525	COG0753	catalase activity
JN215_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS17550	COG1024	Enoyl-CoA hydratase
JN215_RS17700	COG1511	domain protein
JN215_RS17725	COG4689	acetoacetate decarboxylase
JN215_RS17760	COG1309	transcriptional regulator
JN215_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS17840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN215_RS17845	COG2264	protein methyltransferase activity
JN215_RS17850	COG3253	May function as heme-dependent peroxidase
JN215_RS17890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JN215_RS17895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN215_RS17900	COG0531	amino acid
JN215_RS17905	COG0569	domain protein
JN215_RS17955	COG0483	inositol monophosphate 1-phosphatase activity
JN215_RS18050	COG1388	LysM domain
JN215_RS18065	COG1960	acyl-CoA dehydrogenase activity
JN215_RS18070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JN215_RS18080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JN215_RS18095	COG1196	nuclear chromosome segregation
JN215_RS18105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN215_RS18145	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JN215_RS18160	COG1842	Phage shock protein A
JN215_RS18175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JN215_RS18180	COG1674	ftsk spoiiie
JN215_RS18205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN215_RS18215	COG3214	Protein conserved in bacteria
JN215_RS18240	COG1960	acyl-CoA dehydrogenase activity
JN215_RS18245	COG1960	acyl-CoA dehydrogenase activity
JN215_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS18260	COG4770	biotin carboxylase activity
JN215_RS18265	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS18285	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN215_RS18335	COG0686	Belongs to the AlaDH PNT family
JN215_RS18350	COG1185	polyribonucleotide nucleotidyltransferase activity
JN215_RS18380	COG1960	acyl-CoA dehydrogenase activity
JN215_RS18385	COG0183	Belongs to the thiolase family
JN215_RS18390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JN215_RS18395	COG2977	Belongs to the P-Pant transferase superfamily
JN215_RS18400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN215_RS18435	COG0534	Mate efflux family protein
JN215_RS18440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JN215_RS18490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN215_RS18490	COG1648	precorrin-2 dehydrogenase activity
JN215_RS18515	COG0579	oxidoreductase
JN215_RS18530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JN215_RS18545	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JN215_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS18570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN215_RS18585	COG1492	cobalamin metabolic process
JN215_RS18610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JN215_RS18615	COG0750	zinc metalloprotease
JN215_RS18620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JN215_RS18640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JN215_RS18645	COG0575	Belongs to the CDS family
JN215_RS18665	COG0745	RESPONSE REGULATOR receiver
JN215_RS18685	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS18705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN215_RS18730	COG0154	amidase activity
JN215_RS18740	COG0052	Belongs to the universal ribosomal protein uS2 family
JN215_RS18780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JN215_RS18790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN215_RS18805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JN215_RS18825	COG0336	Belongs to the RNA methyltransferase TrmD family
JN215_RS18830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JN215_RS18840	COG0228	four-way junction DNA binding
JN215_RS18850	COG1686	Belongs to the peptidase S11 family
JN215_RS18895	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JN215_RS18915	COG1196	nuclear chromosome segregation
JN215_RS18930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JN215_RS18940	COG0571	ribonuclease III activity
JN215_RS18955	COG0701	Predicted permease
JN215_RS18960	COG0028	Belongs to the TPP enzyme family
JN215_RS18970	COG0742	ribosomal rna small subunit methyltransferase
JN215_RS18985	COG0657	acetylesterase activity
JN215_RS19005	COG1461	Dihydroxyacetone kinase
JN215_RS19070	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN215_RS19075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN215_RS19080	COG1920	GTP binding
JN215_RS19085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JN215_RS19130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN215_RS19135	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN215_RS19140	COG2271	Major facilitator Superfamily
JN215_RS19145	COG2271	Major facilitator Superfamily
JN215_RS19150	COG0473	3-isopropylmalate dehydrogenase activity
JN215_RS19165	COG0655	NAD(P)H dehydrogenase (quinone) activity
JN215_RS19180	COG0028	Belongs to the TPP enzyme family
JN215_RS19190	COG2259	Doxx family
JN215_RS19210	COG1192	Involved in chromosome partitioning
JN215_RS19215	COG0205	6-phosphofructokinase activity
JN215_RS19260	COG0626	cystathionine gamma-synthase activity
JN215_RS19310	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN215_RS19360	COG0142	geranyltranstransferase activity
JN215_RS19390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JN215_RS19430	COG1819	glycosyl
JN215_RS19435	COG1304	FMN binding
JN215_RS19440	COG2409	Drug exporters of the RND superfamily
JN215_RS19450	COG0415	Belongs to the DNA photolyase family
JN215_RS19460	COG0110	maltose O-acetyltransferase activity
JN215_RS19465	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN215_RS19490	COG1024	Enoyl-CoA hydratase
JN215_RS19500	COG1119	ATPase activity
JN215_RS19510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN215_RS19540	COG1309	transcriptional regulator
JN215_RS19550	COG2072	flavoprotein involved in K transport
JN215_RS19555	COG1309	transcriptional regulator
JN215_RS19630	COG2186	Transcriptional regulator
JN215_RS19645	COG1960	acyl-CoA dehydrogenase activity
JN215_RS19655	COG1793	dna ligase
JN215_RS19660	COG0443	Heat shock 70 kDa protein
JN215_RS19670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS19675	COG0183	Belongs to the thiolase family
JN215_RS19680	COG1024	Enoyl-CoA hydratase
JN215_RS19685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS19725	COG2076	Multidrug Resistance protein
JN215_RS19775	COG4638	Rieske (2fe-2S)
JN215_RS19780	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS19805	COG4638	Rieske (2fe-2S)
JN215_RS19820	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS19835	COG3654	unkown
JN215_RS19855	COG0477	Major facilitator Superfamily
JN215_RS19865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN215_RS19870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN215_RS19890	COG2301	Belongs to the HpcH HpaI aldolase family
JN215_RS19905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JN215_RS19940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN215_RS20000	COG4638	Rieske (2fe-2S)
JN215_RS20010	COG1131	(ABC) transporter
JN215_RS20010	COG0842	Transport permease protein
JN215_RS20010	COG1716	ATPase activity
JN215_RS20020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN215_RS20020	COG2755	lipolytic protein G-D-S-L family
JN215_RS20060	COG0243	molybdopterin cofactor binding
JN215_RS20065	COG1309	transcriptional regulator
JN215_RS20085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JN215_RS20090	COG2177	Part of the ABC transporter FtsEX involved in
JN215_RS20095	COG2884	Cell division ATP-binding protein ftsE
JN215_RS20105	COG0668	transmembrane transport
JN215_RS20115	COG0493	'glutamate synthase
JN215_RS20155	COG0483	inositol monophosphate 1-phosphatase activity
JN215_RS20165	COG1960	acyl-CoA dehydrogenase activity
JN215_RS20170	COG0667	Aldo Keto reductase
JN215_RS20175	COG0604	alcohol dehydrogenase
JN215_RS20195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS20200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN215_RS20210	COG1960	acyl-CoA dehydrogenase activity
JN215_RS20225	COG2353	YceI-like domain
JN215_RS20245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN215_RS20265	COG1034	ATP synthesis coupled electron transport
JN215_RS20270	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN215_RS20285	COG0713	ATP synthesis coupled electron transport
JN215_RS20315	COG0714	Associated with various cellular activities
JN215_RS20370	COG0297	glycogen (starch) synthase activity
JN215_RS20425	COG3237	CsbD-like
JN215_RS20435	COG0651	ATP synthesis coupled electron transport
JN215_RS20440	COG1006	Multisubunit Na H antiporter MnhC subunit
JN215_RS20455	COG1320	monovalent cation:proton antiporter activity
JN215_RS20460	COG2212	antiporter activity
JN215_RS20480	COG0028	Belongs to the TPP enzyme family
JN215_RS20485	COG1573	uracil-dna glycosylase
JN215_RS20540	COG0789	Transcriptional regulator
JN215_RS20550	COG3707	response regulator
JN215_RS20560	COG2197	response regulator
JN215_RS20635	COG0386	Belongs to the glutathione peroxidase family
JN215_RS20660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JN215_RS20670	COG0783	Belongs to the Dps family
JN215_RS20680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS20730	COG3480	Lon protease (S16) C-terminal proteolytic domain
JN215_RS20745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN215_RS20770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN215_RS20790	COG0596	Alpha beta hydrolase
JN215_RS20835	COG0513	Belongs to the DEAD box helicase family
JN215_RS20855	COG0406	alpha-ribazole phosphatase activity
JN215_RS20890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JN215_RS20910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JN215_RS20915	COG1063	alcohol dehydrogenase
JN215_RS20930	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS20960	COG2135	peptidase activity
JN215_RS20965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JN215_RS20970	COG1162	GTPase activity
JN215_RS20975	COG1733	regulation of RNA biosynthetic process
JN215_RS20980	COG0183	Belongs to the thiolase family
JN215_RS20995	COG1309	transcriptional regulator
JN215_RS21030	COG2020	methyltransferase activity
JN215_RS21035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JN215_RS21045	COG0653	protein targeting
JN215_RS21050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JN215_RS21065	COG0583	DNA-binding transcription factor activity
JN215_RS21080	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN215_RS21080	COG1024	Enoyl-CoA hydratase
JN215_RS21085	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS21090	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS21100	COG1252	NADH dehydrogenase
JN215_RS21105	COG1595	DNA-templated transcription, initiation
JN215_RS21120	COG2826	transposase and inactivated derivatives, IS30 family
JN215_RS21135	COG0277	FAD linked oxidase domain protein
JN215_RS21145	COG5401	PFAM Sporulation and spore germination
JN215_RS21150	COG5000	phosphorelay sensor kinase activity
JN215_RS21150	COG5002	protein histidine kinase activity
JN215_RS21165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN215_RS21185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN215_RS21190	COG0531	amino acid
JN215_RS21195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS21200	COG1482	cell wall glycoprotein biosynthetic process
JN215_RS21210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN215_RS21250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN215_RS21265	COG1316	TRANSCRIPTIONal
JN215_RS21290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS21295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS21335	COG0784	Response regulator, receiver
JN215_RS21340	COG4251	negative regulation of phosphorylation
JN215_RS21355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JN215_RS21360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JN215_RS21380	COG1053	succinate dehydrogenase
JN215_RS21385	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS21400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN215_RS21410	COG0424	maF-like protein
JN215_RS21425	COG4770	biotin carboxylase activity
JN215_RS21430	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS21460	COG1522	sequence-specific DNA binding
JN215_RS21470	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS21475	COG1309	transcriptional regulator
JN215_RS21480	COG1201	RNA secondary structure unwinding
JN215_RS21520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN215_RS21530	COG0564	pseudouridine synthase activity
JN215_RS21535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JN215_RS21550	COG0657	acetylesterase activity
JN215_RS21555	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN215_RS21555	COG1473	amidohydrolase
JN215_RS21560	COG1473	amidohydrolase
JN215_RS21575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN215_RS21580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JN215_RS21585	COG3511	phospholipase C
JN215_RS21595	COG2304	oxidoreductase activity
JN215_RS21600	COG2304	oxidoreductase activity
JN215_RS21635	COG2009	succinate dehydrogenase
JN215_RS21645	COG1053	succinate dehydrogenase
JN215_RS21650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JN215_RS21665	COG1595	DNA-templated transcription, initiation
JN215_RS21670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JN215_RS21680	COG1686	Belongs to the peptidase S11 family
JN215_RS21685	COG2814	Major facilitator Superfamily
JN215_RS21700	COG1295	ribonuclease BN
JN215_RS21725	COG2873	o-acetylhomoserine
JN215_RS21745	COG1403	HNH endonuclease
JN215_RS21775	COG0842	Transport permease protein
JN215_RS21775	COG1131	(ABC) transporter
JN215_RS21775	COG1716	ATPase activity
JN215_RS21780	COG1357	PFAM Pentapeptide repeats (8 copies)
JN215_RS21795	COG2018	Roadblock/LC7 domain
JN215_RS21810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JN215_RS21825	COG0587	DNA-directed DNA polymerase activity
JN215_RS21830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN215_RS21830	COG1877	trehalose-phosphatase activity
JN215_RS21835	COG2030	dehydratase
JN215_RS21840	COG0406	alpha-ribazole phosphatase activity
JN215_RS21845	COG4221	oxidoreductase activity
JN215_RS21850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS21890	COG0519	Catalyzes the synthesis of GMP from XMP
JN215_RS21890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JN215_RS21895	COG2826	transposase and inactivated derivatives, IS30 family
JN215_RS21985	COG2032	superoxide dismutase activity
JN215_RS22005	COG1309	transcriptional regulator
JN215_RS22015	COG0459	protein refolding
JN215_RS22030	COG0456	acetyltransferase
JN215_RS22035	COG0456	acetyltransferase
JN215_RS22035	COG1214	PFAM Peptidase M22, glycoprotease
JN215_RS22040	COG0802	atpase or kinase
JN215_RS22055	COG0076	glutamate decarboxylase activity
JN215_RS22075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN215_RS22095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS22125	COG4842	Belongs to the WXG100 family
JN215_RS22130	COG4842	Belongs to the WXG100 family
JN215_RS22140	COG1674	ftsk spoiiie
JN215_RS22150	COG1404	Belongs to the peptidase S8 family
JN215_RS22190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JN215_RS22195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JN215_RS22200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JN215_RS22205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JN215_RS22215	COG2205	protein histidine kinase activity
JN215_RS22265	COG3794	PFAM blue (type 1) copper domain protein
JN215_RS22290	COG1960	acyl-CoA dehydrogenase activity
JN215_RS22320	COG0028	Belongs to the TPP enzyme family
JN215_RS22325	COG0577	efflux transmembrane transporter activity
JN215_RS22325	COG1136	(ABC) transporter
JN215_RS22330	COG0577	efflux transmembrane transporter activity
JN215_RS22335	COG2226	methyltransferase
JN215_RS22345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN215_RS22365	COG0563	adenylate kinase activity
JN215_RS22375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS22405	COG1063	alcohol dehydrogenase
JN215_RS22410	COG4221	oxidoreductase activity
JN215_RS22430	COG0616	signal peptide processing
JN215_RS22435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS22450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JN215_RS22455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JN215_RS22480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JN215_RS22490	COG1403	HNH endonuclease
JN215_RS22495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JN215_RS22505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JN215_RS22595	COG0535	radical SAM domain protein
JN215_RS22620	COG0483	inositol monophosphate 1-phosphatase activity
JN215_RS22630	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS22655	COG0049	tRNA binding
JN215_RS22665	COG1309	transcriptional regulator
JN215_RS22695	COG1960	acyl-CoA dehydrogenase activity
JN215_RS22735	COG0222	ribosome binding
JN215_RS22770	COG2318	DinB family
JN215_RS22785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS22790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS22800	COG4941	Belongs to the sigma-70 factor family
JN215_RS22820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JN215_RS22830	COG2030	dehydratase
JN215_RS22835	COG2030	dehydratase
JN215_RS22840	COG2030	dehydratase
JN215_RS22865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN215_RS22880	COG0243	molybdopterin cofactor binding
JN215_RS22890	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN215_RS22905	COG0778	Nitroreductase
JN215_RS22910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS22915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JN215_RS22920	COG1074	ATP-dependent DNA helicase activity
JN215_RS22950	COG3537	Alpha-1,2-mannosidase
JN215_RS22970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JN215_RS23005	COG2124	cytochrome p450
JN215_RS23015	COG1914	H( )-stimulated, divalent metal cation uptake system
JN215_RS23020	COG0243	molybdopterin cofactor binding
JN215_RS23040	COG2072	flavoprotein involved in K transport
JN215_RS23050	COG0659	secondary active sulfate transmembrane transporter activity
JN215_RS23060	COG0501	Belongs to the peptidase M48B family
JN215_RS23065	COG0142	geranyltranstransferase activity
JN215_RS23080	COG2226	methyltransferase
JN215_RS23085	COG0300	oxidoreductase activity
JN215_RS23110	COG4948	Mandelate Racemase Muconate Lactonizing
JN215_RS23115	COG1228	amidohydrolase
JN215_RS23120	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS23130	COG0667	Aldo Keto reductase
JN215_RS23145	COG4221	oxidoreductase activity
JN215_RS23200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN215_RS23205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JN215_RS23230	COG2894	cell division
JN215_RS23235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JN215_RS23245	COG0785	Cytochrome C biogenesis protein
JN215_RS23255	COG0406	alpha-ribazole phosphatase activity
JN215_RS23275	COG4948	Mandelate Racemase Muconate Lactonizing
JN215_RS23280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JN215_RS23290	COG1113	amino acid transport
JN215_RS23310	COG2755	lipolytic protein G-D-S-L family
JN215_RS23310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN215_RS23315	COG2755	lipolytic protein G-D-S-L family
JN215_RS23325	COG1366	Belongs to the anti-sigma-factor antagonist family
JN215_RS23395	COG2030	dehydratase
JN215_RS23465	COG0588	phosphoglycerate mutase activity
JN215_RS23475	COG0438	transferase activity, transferring glycosyl groups
JN215_RS23515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JN215_RS23540	COG2733	membrane
JN215_RS23555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN215_RS23615	COG1505	serine-type exopeptidase activity
JN215_RS23625	COG1024	Enoyl-CoA hydratase
JN215_RS23635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN215_RS23680	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN215_RS23700	COG4221	oxidoreductase activity
JN215_RS23730	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS23740	COG0738	Major facilitator superfamily
JN215_RS23755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN215_RS23805	COG2032	superoxide dismutase activity
JN215_RS23820	COG0242	peptide deformylase activity
JN215_RS23850	COG3707	response regulator
JN215_RS23920	COG1088	dTDP-glucose 4,6-dehydratase activity
JN215_RS23925	COG2234	aminopeptidase activity
JN215_RS23930	COG2234	aminopeptidase activity
JN215_RS23970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN215_RS23970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JN215_RS23990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN215_RS24005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JN215_RS24020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN215_RS24040	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS24045	COG1960	acyl-CoA dehydrogenase activity
JN215_RS24065	COG1252	NADH dehydrogenase
JN215_RS24075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN215_RS24095	COG0406	alpha-ribazole phosphatase activity
JN215_RS24105	COG1994	Peptidase M50
JN215_RS24175	COG0542	response to heat
JN215_RS24195	COG0789	Transcriptional regulator
JN215_RS24200	COG0484	heat shock protein binding
JN215_RS24205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JN215_RS24240	COG2814	Major facilitator Superfamily
JN215_RS24255	COG2181	nitrate reductase activity
JN215_RS24255	COG0247	lactate metabolic process
JN215_RS24285	COG2226	methyltransferase
JN215_RS24290	COG0477	Major facilitator Superfamily
JN215_RS24295	COG2175	clavaminate synthase activity
JN215_RS24300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JN215_RS24345	COG1376	ErfK ybiS ycfS ynhG family protein
JN215_RS24365	COG0246	Mannitol dehydrogenase
JN215_RS24370	COG1070	Carbohydrate kinase
JN215_RS24410	COG2130	NADP-dependent
JN215_RS24470	COG0778	Nitroreductase
JN215_RS24475	COG1368	sulfuric ester hydrolase activity
JN215_RS24495	COG1404	Belongs to the peptidase S8 family
JN215_RS24545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS24550	COG0254	rRNA binding
JN215_RS24565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JN215_RS24570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JN215_RS24575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JN215_RS24615	COG0346	lactoylglutathione lyase activity
JN215_RS24630	COG1960	acyl-CoA dehydrogenase activity
JN215_RS24640	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS24650	COG2223	nitrite transmembrane transporter activity
JN215_RS24665	COG1984	allophanate hydrolase subunit 2
JN215_RS24695	COG2146	nitrite reductase [NAD(P)H] activity
JN215_RS24695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN215_RS24720	COG1053	succinate dehydrogenase
JN215_RS24745	COG1960	acyl-CoA dehydrogenase activity
JN215_RS24750	COG0183	Belongs to the thiolase family
JN215_RS24755	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS24760	COG2030	dehydratase
JN215_RS24775	COG1472	Belongs to the glycosyl hydrolase 3 family
JN215_RS24790	COG4981	capsule polysaccharide biosynthetic process
JN215_RS24800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN215_RS24860	COG0028	Belongs to the TPP enzyme family
JN215_RS24865	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS24870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JN215_RS24925	COG0586	Pfam SNARE associated Golgi protein
JN215_RS24945	COG1309	transcriptional regulator
JN215_RS24955	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS24960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JN215_RS24965	COG1024	Enoyl-CoA hydratase
JN215_RS24975	COG0657	acetylesterase activity
JN215_RS24985	COG2267	carboxylic ester hydrolase activity
JN215_RS24995	COG1228	amidohydrolase
JN215_RS25020	COG1024	Enoyl-CoA hydratase
JN215_RS25030	COG2203	Gaf domain
JN215_RS25030	COG2199	diguanylate cyclase activity
JN215_RS25035	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JN215_RS25050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JN215_RS25100	COG3590	peptidase
JN215_RS25105	COG0243	molybdopterin cofactor binding
JN215_RS25115	COG1376	ErfK ybiS ycfS ynhG family protein
JN215_RS25120	COG2814	Major facilitator Superfamily
JN215_RS25125	COG1937	Protein conserved in bacteria
JN215_RS25130	COG0129	dihydroxy-acid dehydratase activity
JN215_RS25145	COG4122	O-methyltransferase activity
JN215_RS25155	COG1472	Belongs to the glycosyl hydrolase 3 family
JN215_RS25170	COG2267	carboxylic ester hydrolase activity
JN215_RS25210	COG3619	membrane
JN215_RS25225	COG1714	RDD family
JN215_RS25240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN215_RS25265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS25270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN215_RS25280	COG1802	Transcriptional regulator
JN215_RS25310	COG0657	acetylesterase activity
JN215_RS25335	COG1063	alcohol dehydrogenase
JN215_RS25340	COG2124	cytochrome p450
JN215_RS25370	COG1960	acyl-CoA dehydrogenase activity
JN215_RS25375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS25405	COG0277	FAD linked oxidase domain protein
JN215_RS25425	COG1309	transcriptional regulator
JN215_RS25455	COG1960	acyl-CoA dehydrogenase activity
JN215_RS25460	COG2365	Tyrosine phosphatase family
JN215_RS25465	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS25470	COG1012	belongs to the aldehyde dehydrogenase family
JN215_RS25495	COG1741	Belongs to the pirin family
JN215_RS25500	COG0783	Belongs to the Dps family
JN215_RS25520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JN215_RS25535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN215_RS25550	COG3585	molybdate ion transport
JN215_RS25555	COG0596	Alpha beta hydrolase
JN215_RS25575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS25610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN215_RS25620	COG3546	catalase activity
JN215_RS25655	COG1129	ABC transporter
JN215_RS25655	COG0842	Transport permease protein
JN215_RS25675	COG3281	Trehalose synthase
JN215_RS25685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN215_RS25705	COG0028	Belongs to the TPP enzyme family
JN215_RS25710	COG0583	DNA-binding transcription factor activity
JN215_RS25715	COG1376	ErfK ybiS ycfS ynhG family protein
JN215_RS25750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN215_RS25750	COG2755	lipolytic protein G-D-S-L family
JN215_RS25760	COG0028	Belongs to the TPP enzyme family
JN215_RS25765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS25770	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS25775	COG2072	flavoprotein involved in K transport
JN215_RS25785	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS25790	COG3386	PFAM SMP-30 Gluconolaconase
JN215_RS25800	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS25810	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS25855	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS25870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JN215_RS25890	COG2226	methyltransferase
JN215_RS25900	COG0300	oxidoreductase activity
JN215_RS25945	COG1063	alcohol dehydrogenase
JN215_RS25965	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS25970	COG2072	flavoprotein involved in K transport
JN215_RS25995	COG0583	DNA-binding transcription factor activity
JN215_RS26015	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS26035	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN215_RS26055	COG1309	transcriptional regulator
JN215_RS26065	COG1028	Short-chain dehydrogenase reductase Sdr
JN215_RS26070	COG0318	PFAM AMP-dependent synthetase and ligase
JN215_RS26095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN215_RS26120	COG1960	acyl-CoA dehydrogenase activity
JN215_RS26125	COG1309	transcriptional regulator
JN215_RS26150	COG3588	fructose-bisphosphate aldolase
JN215_RS26185	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN215_RS26190	COG4638	Rieske (2fe-2S)
JN215_RS26200	COG2197	response regulator
JN215_RS26205	COG4585	Histidine kinase
JN215_RS26220	COG1674	ftsk spoiiie
JN215_RS26295	COG1595	DNA-templated transcription, initiation
JN215_RS26315	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN215_RS26315	COG3409	Peptidoglycan-binding domain 1 protein
JN215_RS26330	COG1192	Involved in chromosome partitioning
JN215_RS26335	COG0357	Ribosomal RNA small subunit methyltransferase G
JN215_RS26345	COG0706	membrane insertase activity
JN215_RS26350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane