locus-tag	class	description
MSG_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MSG_RS00010	COG0592	DNA-directed DNA polymerase activity
MSG_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MSG_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MSG_RS00025	COG0187	DNA topoisomerase II activity
MSG_RS00100	COG0515	serine threonine protein kinase
MSG_RS00100	COG2815	serine threonine protein kinase
MSG_RS00130	COG1716	ATPase activity
MSG_RS00145	COG0384	phenazine biosynthesis protein PhzF
MSG_RS00175	COG1960	acyl-CoA dehydrogenase activity
MSG_RS00275	COG0495	leucyl-tRNA aminoacylation
MSG_RS00280	COG0300	oxidoreductase activity
MSG_RS00295	COG0765	amino acid transport
MSG_RS00305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00310	COG1309	transcriptional regulator
MSG_RS00315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MSG_RS00315	COG0596	Alpha beta hydrolase
MSG_RS00335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MSG_RS00375	COG0360	Binds together with S18 to 16S ribosomal RNA
MSG_RS00465	COG3706	GGDEF domain
MSG_RS00490	COG0300	oxidoreductase activity
MSG_RS00530	COG2814	Major facilitator Superfamily
MSG_RS00535	COG0583	DNA-binding transcription factor activity
MSG_RS00550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS00585	COG0477	Major facilitator Superfamily
MSG_RS00590	COG1051	belongs to the nudix hydrolase family
MSG_RS00600	COG0753	catalase activity
MSG_RS00605	COG2175	clavaminate synthase activity
MSG_RS00620	COG1116	anion transmembrane transporter activity
MSG_RS00625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MSG_RS00630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MSG_RS00645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MSG_RS00665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS00690	COG1960	acyl-CoA dehydrogenase activity
MSG_RS00695	COG1309	transcriptional regulator
MSG_RS00700	COG3588	fructose-bisphosphate aldolase
MSG_RS00705	COG0243	molybdopterin cofactor binding
MSG_RS00705	COG3383	formate dehydrogenase (NAD+) activity
MSG_RS00710	COG3383	formate dehydrogenase (NAD+) activity
MSG_RS00710	COG0243	molybdopterin cofactor binding
MSG_RS00715	COG0437	4 iron, 4 sulfur cluster binding
MSG_RS00725	COG0709	Synthesizes selenophosphate from selenide and ATP
MSG_RS00745	COG2205	protein histidine kinase activity
MSG_RS00750	COG0659	secondary active sulfate transmembrane transporter activity
MSG_RS00755	COG2226	methyltransferase
MSG_RS00770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MSG_RS00785	COG0657	acetylesterase activity
MSG_RS00790	COG1309	transcriptional regulator
MSG_RS00795	COG1960	acyl-CoA dehydrogenase activity
MSG_RS00830	COG1609	Transcriptional regulator
MSG_RS00865	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS00880	COG1309	transcriptional regulator
MSG_RS00930	COG2072	flavoprotein involved in K transport
MSG_RS00935	COG2072	flavoprotein involved in K transport
MSG_RS00950	COG0659	secondary active sulfate transmembrane transporter activity
MSG_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS00975	COG0583	DNA-binding transcription factor activity
MSG_RS01005	COG0300	oxidoreductase activity
MSG_RS01015	COG4221	oxidoreductase activity
MSG_RS01045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MSG_RS01050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MSG_RS01055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MSG_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS01110	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS01120	COG3386	PFAM SMP-30 Gluconolaconase
MSG_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS01135	COG2072	flavoprotein involved in K transport
MSG_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS01160	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MSG_RS01160	COG2755	lipolytic protein G-D-S-L family
MSG_RS01180	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS01180	COG0604	alcohol dehydrogenase
MSG_RS01180	COG3321	synthase
MSG_RS01195	COG1376	ErfK ybiS ycfS ynhG family protein
MSG_RS01210	COG0028	Belongs to the TPP enzyme family
MSG_RS01235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MSG_RS01255	COG3415	Transposase
MSG_RS01255	COG2801	Transposase and inactivated derivatives
MSG_RS01295	COG1960	acyl-CoA dehydrogenase activity
MSG_RS01300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS01310	COG1309	transcriptional regulator
MSG_RS01380	COG3321	synthase
MSG_RS01380	COG0604	alcohol dehydrogenase
MSG_RS01385	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS01420	COG2084	Dehydrogenase
MSG_RS01430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MSG_RS01455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MSG_RS01485	COG0783	Belongs to the Dps family
MSG_RS01490	COG0038	chloride channel
MSG_RS01495	COG1741	Belongs to the pirin family
MSG_RS01520	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS01530	COG2365	Tyrosine phosphatase family
MSG_RS01565	COG1309	transcriptional regulator
MSG_RS01580	COG0277	FAD linked oxidase domain protein
MSG_RS01615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS01685	COG0657	acetylesterase activity
MSG_RS01705	COG1802	Transcriptional regulator
MSG_RS01715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS01720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS01745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MSG_RS01775	COG3619	membrane
MSG_RS01825	COG2267	carboxylic ester hydrolase activity
MSG_RS01840	COG1472	Belongs to the glycosyl hydrolase 3 family
MSG_RS01850	COG4122	O-methyltransferase activity
MSG_RS01855	COG0129	dihydroxy-acid dehydratase activity
MSG_RS01860	COG1937	Protein conserved in bacteria
MSG_RS01865	COG2814	Major facilitator Superfamily
MSG_RS01870	COG1376	ErfK ybiS ycfS ynhG family protein
MSG_RS01880	COG0243	molybdopterin cofactor binding
MSG_RS01885	COG3590	peptidase
MSG_RS01925	COG2409	Drug exporters of the RND superfamily
MSG_RS01950	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MSG_RS01965	COG1024	Enoyl-CoA hydratase
MSG_RS02000	COG2146	nitrite reductase [NAD(P)H] activity
MSG_RS02005	COG0657	acetylesterase activity
MSG_RS02015	COG1024	Enoyl-CoA hydratase
MSG_RS02025	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS02035	COG1309	transcriptional regulator
MSG_RS02050	COG0297	glycogen (starch) synthase activity
MSG_RS02095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MSG_RS02100	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS02105	COG0028	Belongs to the TPP enzyme family
MSG_RS02135	COG4981	capsule polysaccharide biosynthetic process
MSG_RS02150	COG1472	Belongs to the glycosyl hydrolase 3 family
MSG_RS02165	COG2030	dehydratase
MSG_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS02175	COG0183	Belongs to the thiolase family
MSG_RS02180	COG1960	acyl-CoA dehydrogenase activity
MSG_RS02200	COG1053	succinate dehydrogenase
MSG_RS02250	COG0745	RESPONSE REGULATOR receiver
MSG_RS02270	COG1984	allophanate hydrolase subunit 2
MSG_RS02275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MSG_RS02290	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS02305	COG1960	acyl-CoA dehydrogenase activity
MSG_RS02310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MSG_RS02325	COG0346	lactoylglutathione lyase activity
MSG_RS02405	COG1404	Belongs to the peptidase S8 family
MSG_RS02425	COG1368	sulfuric ester hydrolase activity
MSG_RS02435	COG0778	Nitroreductase
MSG_RS02455	COG0671	phosphoesterase, PA-phosphatase related
MSG_RS02495	COG2130	NADP-dependent
MSG_RS02565	COG1376	ErfK ybiS ycfS ynhG family protein
MSG_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS02630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MSG_RS02660	COG2181	nitrate reductase activity
MSG_RS02660	COG0247	lactate metabolic process
MSG_RS02715	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS02720	COG0583	DNA-binding transcription factor activity
MSG_RS02740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MSG_RS02745	COG0484	heat shock protein binding
MSG_RS02750	COG0789	Transcriptional regulator
MSG_RS02780	COG0542	response to heat
MSG_RS02785	COG1024	Enoyl-CoA hydratase
MSG_RS02815	COG4303	Ethanolamine ammonia lyase large subunit
MSG_RS02825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MSG_RS02830	COG0586	Pfam SNARE associated Golgi protein
MSG_RS02835	COG0191	fructose-bisphosphate aldolase activity
MSG_RS02855	COG1994	Peptidase M50
MSG_RS02875	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MSG_RS02880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MSG_RS02890	COG1252	NADH dehydrogenase
MSG_RS02910	COG0596	Alpha beta hydrolase
MSG_RS02920	COG1960	acyl-CoA dehydrogenase activity
MSG_RS02940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS02950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS02955	COG1742	UPF0060 membrane protein
MSG_RS02960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS02965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS03000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MSG_RS03055	COG2234	aminopeptidase activity
MSG_RS03060	COG2234	aminopeptidase activity
MSG_RS03125	COG0242	peptide deformylase activity
MSG_RS03140	COG2032	superoxide dismutase activity
MSG_RS03170	COG0477	Major facilitator Superfamily
MSG_RS03175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MSG_RS03210	COG4221	oxidoreductase activity
MSG_RS03220	COG0459	protein refolding
MSG_RS03240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MSG_RS03240	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MSG_RS03265	COG1595	DNA-templated transcription, initiation
MSG_RS03305	COG1024	Enoyl-CoA hydratase
MSG_RS03315	COG1505	serine-type exopeptidase activity
MSG_RS03375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS03390	COG2733	membrane
MSG_RS03435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MSG_RS03500	COG0248	Ppx GppA phosphatase
MSG_RS03540	COG0204	Acyl-transferase
MSG_RS03550	COG2030	dehydratase
MSG_RS03590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MSG_RS03620	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS03625	COG2755	lipolytic protein G-D-S-L family
MSG_RS03625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MSG_RS03630	COG2755	lipolytic protein G-D-S-L family
MSG_RS03640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MSG_RS03640	COG2755	lipolytic protein G-D-S-L family
MSG_RS03650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS03665	COG1113	amino acid transport
MSG_RS03675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MSG_RS03680	COG0406	alpha-ribazole phosphatase activity
MSG_RS03690	COG0785	Cytochrome C biogenesis protein
MSG_RS03700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MSG_RS03710	COG3415	Transposase
MSG_RS03710	COG2801	Transposase and inactivated derivatives
MSG_RS03725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MSG_RS03735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MSG_RS03740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MSG_RS03790	COG0306	phosphate transporter
MSG_RS03800	COG4221	oxidoreductase activity
MSG_RS03815	COG0667	Aldo Keto reductase
MSG_RS03825	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS03830	COG1228	amidohydrolase
MSG_RS03835	COG4948	Mandelate Racemase Muconate Lactonizing
MSG_RS03845	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MSG_RS03860	COG4221	oxidoreductase activity
MSG_RS03885	COG0142	geranyltranstransferase activity
MSG_RS03890	COG0501	Belongs to the peptidase M48B family
MSG_RS03900	COG0659	secondary active sulfate transmembrane transporter activity
MSG_RS03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MSG_RS03955	COG4638	Rieske (2fe-2S)
MSG_RS04005	COG3537	Alpha-1,2-mannosidase
MSG_RS04030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MSG_RS04040	COG1752	Esterase of the alpha-beta hydrolase superfamily
MSG_RS04045	COG1024	Enoyl-CoA hydratase
MSG_RS04055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS04085	COG2030	dehydratase
MSG_RS04090	COG2030	dehydratase
MSG_RS04100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MSG_RS04120	COG4941	Belongs to the sigma-70 factor family
MSG_RS04130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS04135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS04140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS04145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS04180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MSG_RS04185	COG0222	ribosome binding
MSG_RS04235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MSG_RS04240	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MSG_RS04245	COG1960	acyl-CoA dehydrogenase activity
MSG_RS04260	COG1024	Enoyl-CoA hydratase
MSG_RS04275	COG1309	transcriptional regulator
MSG_RS04280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MSG_RS04285	COG0049	tRNA binding
MSG_RS04290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MSG_RS04320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MSG_RS04340	COG0535	radical SAM domain protein
MSG_RS04480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MSG_RS04485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MSG_RS04500	COG0255	Belongs to the universal ribosomal protein uL29 family
MSG_RS04505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MSG_RS04530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MSG_RS04545	COG0277	FAD linked oxidase domain protein
MSG_RS04560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MSG_RS04585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MSG_RS04590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MSG_RS04610	COG0616	signal peptide processing
MSG_RS04645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MSG_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS04665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MSG_RS04680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS04685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS04690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS04820	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MSG_RS04825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MSG_RS04830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MSG_RS04835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MSG_RS04845	COG0202	RNA polymerase activity
MSG_RS04875	COG1404	Belongs to the peptidase S8 family
MSG_RS04885	COG1674	ftsk spoiiie
MSG_RS04895	COG4842	Belongs to the WXG100 family
MSG_RS04900	COG4842	Belongs to the WXG100 family
MSG_RS04910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MSG_RS04915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MSG_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS04945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MSG_RS04960	COG2308	Evidence 4 Homologs of previously reported genes of
MSG_RS04960	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MSG_RS04970	COG2267	carboxylic ester hydrolase activity
MSG_RS04980	COG0076	glutamate decarboxylase activity
MSG_RS04985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MSG_RS04995	COG0802	atpase or kinase
MSG_RS05005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MSG_RS05010	COG0477	Major facilitator Superfamily
MSG_RS05020	COG0456	acetyltransferase
MSG_RS05035	COG0459	protein refolding
MSG_RS05060	COG2860	membrane
MSG_RS05075	COG2032	superoxide dismutase activity
MSG_RS05155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MSG_RS05160	COG0477	Major facilitator Superfamily
MSG_RS05165	COG1733	regulation of RNA biosynthetic process
MSG_RS05170	COG0519	Catalyzes the synthesis of GMP from XMP
MSG_RS05170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MSG_RS05200	COG4221	oxidoreductase activity
MSG_RS05205	COG0406	alpha-ribazole phosphatase activity
MSG_RS05210	COG2030	dehydratase
MSG_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MSG_RS05225	COG0587	DNA-directed DNA polymerase activity
MSG_RS05245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MSG_RS05255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MSG_RS05265	COG5002	protein histidine kinase activity
MSG_RS05270	COG2018	Roadblock/LC7 domain
MSG_RS05285	COG1357	PFAM Pentapeptide repeats (8 copies)
MSG_RS05290	COG1716	ATPase activity
MSG_RS05290	COG1131	(ABC) transporter
MSG_RS05290	COG0842	Transport permease protein
MSG_RS05295	COG1131	(ABC) transporter
MSG_RS05295	COG1716	ATPase activity
MSG_RS05295	COG0842	Transport permease protein
MSG_RS05320	COG0277	FAD linked oxidase domain protein
MSG_RS05340	COG0531	amino acid
MSG_RS05345	COG0531	amino acid
MSG_RS05355	COG2226	methyltransferase
MSG_RS05370	COG2873	o-acetylhomoserine
MSG_RS05395	COG1295	ribonuclease BN
MSG_RS05405	COG2814	Major facilitator Superfamily
MSG_RS05425	COG1686	Belongs to the peptidase S11 family
MSG_RS05440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MSG_RS05445	COG1595	DNA-templated transcription, initiation
MSG_RS05465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MSG_RS05470	COG1053	succinate dehydrogenase
MSG_RS05480	COG2009	succinate dehydrogenase
MSG_RS05530	COG2304	oxidoreductase activity
MSG_RS05535	COG2304	oxidoreductase activity
MSG_RS05545	COG3511	phospholipase C
MSG_RS05550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MSG_RS05555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MSG_RS05570	COG1473	amidohydrolase
MSG_RS05575	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MSG_RS05575	COG1473	amidohydrolase
MSG_RS05595	COG0564	pseudouridine synthase activity
MSG_RS05610	COG0069	glutamate synthase activity
MSG_RS05625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MSG_RS05645	COG1201	RNA secondary structure unwinding
MSG_RS05650	COG1309	transcriptional regulator
MSG_RS05675	COG4770	biotin carboxylase activity
MSG_RS05690	COG0424	maF-like protein
MSG_RS05700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MSG_RS05705	COG1053	succinate dehydrogenase
MSG_RS05710	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MSG_RS05710	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MSG_RS05725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MSG_RS05745	COG4251	negative regulation of phosphorylation
MSG_RS05750	COG0784	Response regulator, receiver
MSG_RS05755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS05760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS05765	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS05795	COG1316	TRANSCRIPTIONal
MSG_RS05810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MSG_RS05830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MSG_RS05860	COG1482	cell wall glycoprotein biosynthetic process
MSG_RS05865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS05870	COG0531	amino acid
MSG_RS05875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MSG_RS05895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MSG_RS05910	COG5002	protein histidine kinase activity
MSG_RS05910	COG5000	phosphorelay sensor kinase activity
MSG_RS05915	COG5401	PFAM Sporulation and spore germination
MSG_RS05925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MSG_RS05930	COG0653	protein targeting
MSG_RS05935	COG1113	amino acid transport
MSG_RS05945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MSG_RS05945	COG4651	solute:proton antiporter activity
MSG_RS05960	COG2326	polyphosphate kinase activity
MSG_RS05990	COG2217	Heavy metal translocating P-type atpase
MSG_RS05995	COG0640	Transcriptional regulator
MSG_RS06050	COG0183	Belongs to the thiolase family
MSG_RS06055	COG1733	regulation of RNA biosynthetic process
MSG_RS06060	COG1162	GTPase activity
MSG_RS06065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MSG_RS06070	COG2135	peptidase activity
MSG_RS06085	COG3104	oligopeptide transport
MSG_RS06095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MSG_RS06110	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS06175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MSG_RS06210	COG0406	alpha-ribazole phosphatase activity
MSG_RS06225	COG0513	Belongs to the DEAD box helicase family
MSG_RS06270	COG0596	Alpha beta hydrolase
MSG_RS06315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MSG_RS06335	COG3480	Lon protease (S16) C-terminal proteolytic domain
MSG_RS06410	COG2508	Transcriptional regulator
MSG_RS06425	COG0386	Belongs to the glutathione peroxidase family
MSG_RS06450	COG3707	response regulator
MSG_RS06460	COG0789	Transcriptional regulator
MSG_RS06585	COG2201	protein-glutamate methylesterase activity
MSG_RS06640	COG0477	Major facilitator Superfamily
MSG_RS06665	COG0300	oxidoreductase activity
MSG_RS06685	COG0714	Associated with various cellular activities
MSG_RS06715	COG0713	ATP synthesis coupled electron transport
MSG_RS06730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MSG_RS06735	COG1034	ATP synthesis coupled electron transport
MSG_RS06755	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MSG_RS06760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MSG_RS06770	COG0477	Major facilitator Superfamily
MSG_RS06780	COG2353	YceI-like domain
MSG_RS06795	COG1960	acyl-CoA dehydrogenase activity
MSG_RS06805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MSG_RS06810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS06830	COG0604	alcohol dehydrogenase
MSG_RS06835	COG1960	acyl-CoA dehydrogenase activity
MSG_RS06845	COG0483	inositol monophosphate 1-phosphatase activity
MSG_RS06860	COG0493	'glutamate synthase
MSG_RS06870	COG0668	transmembrane transport
MSG_RS06880	COG2884	Cell division ATP-binding protein ftsE
MSG_RS06885	COG2177	Part of the ABC transporter FtsEX involved in
MSG_RS06890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MSG_RS06940	COG4585	Histidine kinase
MSG_RS06960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS06965	COG1032	radical SAM domain protein
MSG_RS06985	COG4638	Rieske (2fe-2S)
MSG_RS06990	COG1024	Enoyl-CoA hydratase
MSG_RS07020	COG0784	Response regulator, receiver
MSG_RS07050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MSG_RS07075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MSG_RS07085	COG2814	Major facilitator Superfamily
MSG_RS07095	COG0488	(ABC) transporter
MSG_RS07105	COG2409	Drug exporters of the RND superfamily
MSG_RS07110	COG0142	geranyltranstransferase activity
MSG_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS07175	COG0346	lactoylglutathione lyase activity
MSG_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS07195	COG0058	SHG alpha-glucan phosphorylase activity
MSG_RS07205	COG2076	Multidrug Resistance protein
MSG_RS07235	COG0443	Heat shock 70 kDa protein
MSG_RS07245	COG1966	Carbon starvation protein
MSG_RS07250	COG1793	dna ligase
MSG_RS07260	COG1960	acyl-CoA dehydrogenase activity
MSG_RS07275	COG2186	Transcriptional regulator
MSG_RS07330	COG1309	transcriptional regulator
MSG_RS07355	COG0789	Transcriptional regulator
MSG_RS07360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MSG_RS07365	COG1309	transcriptional regulator
MSG_RS07370	COG2072	flavoprotein involved in K transport
MSG_RS07380	COG0300	oxidoreductase activity
MSG_RS07415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MSG_RS07465	COG1119	ATPase activity
MSG_RS07510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MSG_RS07515	COG0110	maltose O-acetyltransferase activity
MSG_RS07525	COG0415	Belongs to the DNA photolyase family
MSG_RS07535	COG2409	Drug exporters of the RND superfamily
MSG_RS07550	COG1304	FMN binding
MSG_RS07600	COG0142	geranyltranstransferase activity
MSG_RS07635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MSG_RS07675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MSG_RS07680	COG0626	cystathionine gamma-synthase activity
MSG_RS07730	COG0205	6-phosphofructokinase activity
MSG_RS07760	COG0028	Belongs to the TPP enzyme family
MSG_RS07775	COG0655	NAD(P)H dehydrogenase (quinone) activity
MSG_RS07790	COG0473	3-isopropylmalate dehydrogenase activity
MSG_RS07800	COG0179	Fumarylacetoacetate (FAA) hydrolase
MSG_RS07805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MSG_RS07830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MSG_RS07850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MSG_RS07855	COG1920	GTP binding
MSG_RS07860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MSG_RS07890	COG1461	Dihydroxyacetone kinase
MSG_RS07895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MSG_RS07930	COG1228	amidohydrolase
MSG_RS07945	COG0656	L-ascorbic acid biosynthetic process
MSG_RS07950	COG0657	acetylesterase activity
MSG_RS07965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MSG_RS07970	COG0742	ribosomal rna small subunit methyltransferase
MSG_RS07990	COG3321	synthase
MSG_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS07990	COG0604	alcohol dehydrogenase
MSG_RS08000	COG0701	Predicted permease
MSG_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS08050	COG0604	alcohol dehydrogenase
MSG_RS08050	COG3321	synthase
MSG_RS08065	COG3599	regulation of cell shape
MSG_RS08075	COG0571	ribonuclease III activity
MSG_RS08110	COG1196	nuclear chromosome segregation
MSG_RS08135	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MSG_RS08175	COG1686	Belongs to the peptidase S11 family
MSG_RS08205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MSG_RS08210	COG0336	Belongs to the RNA methyltransferase TrmD family
MSG_RS08220	COG0335	large ribosomal subunit rRNA binding
MSG_RS08230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MSG_RS08245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MSG_RS08310	COG0052	Belongs to the universal ribosomal protein uS2 family
MSG_RS08320	COG0154	amidase activity
MSG_RS08345	COG0745	RESPONSE REGULATOR receiver
MSG_RS08365	COG0575	Belongs to the CDS family
MSG_RS08370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MSG_RS08395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MSG_RS08400	COG0750	zinc metalloprotease
MSG_RS08405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MSG_RS08430	COG1492	cobalamin metabolic process
MSG_RS08440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MSG_RS08445	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
MSG_RS08450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MSG_RS08495	COG1648	precorrin-2 dehydrogenase activity
MSG_RS08495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MSG_RS08520	COG0779	Required for maturation of 30S ribosomal subunits
MSG_RS08535	COG0481	GTPase activity
MSG_RS08545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MSG_RS08585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MSG_RS08590	COG2977	Belongs to the P-Pant transferase superfamily
MSG_RS08595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MSG_RS08605	COG0183	Belongs to the thiolase family
MSG_RS08610	COG1960	acyl-CoA dehydrogenase activity
MSG_RS08630	COG1185	polyribonucleotide nucleotidyltransferase activity
MSG_RS08650	COG0686	Belongs to the AlaDH PNT family
MSG_RS08655	COG1522	sequence-specific DNA binding
MSG_RS08685	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MSG_RS08700	COG2801	Transposase and inactivated derivatives
MSG_RS08700	COG3415	Transposase
MSG_RS08725	COG4770	biotin carboxylase activity
MSG_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS08740	COG1960	acyl-CoA dehydrogenase activity
MSG_RS08745	COG1960	acyl-CoA dehydrogenase activity
MSG_RS08765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MSG_RS08780	COG3214	Protein conserved in bacteria
MSG_RS08800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MSG_RS08840	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MSG_RS08855	COG1842	Phage shock protein A
MSG_RS08865	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MSG_RS08895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MSG_RS08905	COG1196	nuclear chromosome segregation
MSG_RS08930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MSG_RS08935	COG1960	acyl-CoA dehydrogenase activity
MSG_RS08950	COG1388	LysM domain
MSG_RS08960	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MSG_RS09030	COG0251	oxidation-reduction process
MSG_RS09040	COG1940	carbohydrate kinase activity
MSG_RS09065	COG0756	dUTP diphosphatase activity
MSG_RS09095	COG0569	domain protein
MSG_RS09100	COG0531	amino acid
MSG_RS09105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MSG_RS09115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MSG_RS09155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MSG_RS09180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MSG_RS09235	COG1819	glycosyl
MSG_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS09485	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MSG_RS09490	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS09495	COG1309	transcriptional regulator
MSG_RS09510	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS09515	COG0701	Predicted permease
MSG_RS09555	COG2070	2-Nitropropane dioxygenase
MSG_RS09560	COG4762	Protein conserved in bacteria
MSG_RS09565	COG0667	Aldo Keto reductase
MSG_RS09575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MSG_RS09585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MSG_RS09595	COG0438	transferase activity, transferring glycosyl groups
MSG_RS09605	COG5651	PPE family
MSG_RS09605	COG3391	amine dehydrogenase activity
MSG_RS09620	COG1946	Acyl-CoA thioesterase
MSG_RS09640	COG3766	membrane
MSG_RS09660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MSG_RS09685	COG3320	Male sterility
MSG_RS09685	COG1022	Amp-dependent synthetase and ligase
MSG_RS09700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MSG_RS09705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MSG_RS09710	COG0747	negative chemotaxis
MSG_RS09715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MSG_RS09720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MSG_RS09735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MSG_RS09745	COG0124	histidyl-tRNA synthetase
MSG_RS09760	COG3973	AAA domain
MSG_RS09795	COG0657	acetylesterase activity
MSG_RS09845	COG1309	transcriptional regulator
MSG_RS09860	COG5473	translation initiation factor activity
MSG_RS09875	COG0432	Pfam Uncharacterised protein family UPF0047
MSG_RS09880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MSG_RS09885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MSG_RS09895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MSG_RS09920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MSG_RS09935	COG0006	proline dipeptidase activity
MSG_RS10010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MSG_RS10015	COG2218	PFAM glutamate synthase alpha subunit domain protein
MSG_RS10020	COG0069	glutamate synthase activity
MSG_RS10045	COG1024	Enoyl-CoA hydratase
MSG_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS10095	COG1176	ABC-type spermidine putrescine transport system, permease component I
MSG_RS10100	COG1177	transmembrane transport
MSG_RS10105	COG3842	ATPase activity
MSG_RS10110	COG1231	oxidoreductase activity
MSG_RS10115	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS10120	COG2186	Transcriptional regulator
MSG_RS10135	COG1335	isochorismatase
MSG_RS10145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MSG_RS10155	COG2188	Transcriptional regulator
MSG_RS10180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MSG_RS10185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MSG_RS10215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MSG_RS10235	COG0505	Belongs to the CarA family
MSG_RS10245	COG0284	orotidine-5'-phosphate decarboxylase activity
MSG_RS10255	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MSG_RS10270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MSG_RS10285	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MSG_RS10300	COG0657	acetylesterase activity
MSG_RS10370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MSG_RS10385	COG0322	excinuclease ABC activity
MSG_RS10390	COG1660	Displays ATPase and GTPase activities
MSG_RS10395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MSG_RS10425	COG0657	acetylesterase activity
MSG_RS10430	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS10455	COG0126	phosphoglycerate kinase activity
MSG_RS10470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MSG_RS10510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MSG_RS10545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MSG_RS10555	COG1131	(ABC) transporter
MSG_RS10580	COG0396	ATPase activity
MSG_RS10590	COG0822	iron-sulfur transferase activity
MSG_RS10595	COG2151	metal-sulfur cluster biosynthetic enzyme
MSG_RS10605	COG1960	acyl-CoA dehydrogenase activity
MSG_RS10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MSG_RS10620	COG0488	(ABC) transporter
MSG_RS10630	COG1309	transcriptional regulator
MSG_RS10635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MSG_RS10655	COG0714	Associated with various cellular activities
MSG_RS10665	COG2304	oxidoreductase activity
MSG_RS10680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MSG_RS10685	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MSG_RS10740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS10835	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MSG_RS10910	COG3321	synthase
MSG_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS10910	COG0604	alcohol dehydrogenase
MSG_RS10915	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS10925	COG2070	2-Nitropropane dioxygenase
MSG_RS10935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MSG_RS10940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MSG_RS10950	COG0252	asparaginase activity
MSG_RS10975	COG2346	COG2346, Truncated hemoglobins
MSG_RS11025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MSG_RS11030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS11055	COG0791	NLP P60 protein
MSG_RS11055	COG3883	PFAM NLP P60 protein
MSG_RS11065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MSG_RS11070	COG0156	8-amino-7-oxononanoate synthase activity
MSG_RS11075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MSG_RS11125	COG0494	nUDIX hydrolase
MSG_RS11165	COG0131	Imidazoleglycerol-phosphate dehydratase
MSG_RS11170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MSG_RS11175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MSG_RS11180	COG0483	inositol monophosphate 1-phosphatase activity
MSG_RS11185	COG0107	imidazoleglycerol-phosphate synthase activity
MSG_RS11190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MSG_RS11205	COG0387	Pfam Sodium calcium exchanger
MSG_RS11215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MSG_RS11260	COG1946	Acyl-CoA thioesterase
MSG_RS11270	COG1132	(ABC) transporter
MSG_RS11275	COG4988	ABC transporter
MSG_RS11280	COG1294	oxidase, subunit
MSG_RS11285	COG1271	oxidase subunit
MSG_RS11365	COG1716	ATPase activity
MSG_RS11365	COG0842	Transport permease protein
MSG_RS11365	COG1131	(ABC) transporter
MSG_RS11405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS11410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MSG_RS11430	COG1305	Transglutaminase-like
MSG_RS11450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MSG_RS11460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MSG_RS11465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MSG_RS11485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MSG_RS11490	COG0072	phenylalanine-tRNA ligase activity
MSG_RS11490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MSG_RS11500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MSG_RS11530	COG0165	Argininosuccinate lyase
MSG_RS11540	COG3321	synthase
MSG_RS11540	COG0604	alcohol dehydrogenase
MSG_RS11545	COG0604	alcohol dehydrogenase
MSG_RS11545	COG3321	synthase
MSG_RS11550	COG3321	synthase
MSG_RS11550	COG0604	alcohol dehydrogenase
MSG_RS11550	COG3321	synthase
MSG_RS11550	COG0604	alcohol dehydrogenase
MSG_RS11565	COG0488	(ABC) transporter
MSG_RS11615	COG1404	Belongs to the peptidase S8 family
MSG_RS11640	COG2835	tetraacyldisaccharide 4'-kinase activity
MSG_RS11655	COG1131	(ABC) transporter
MSG_RS11685	COG0647	UMP catabolic process
MSG_RS11725	COG0494	nUDIX hydrolase
MSG_RS11740	COG2828	Protein conserved in bacteria
MSG_RS11750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MSG_RS11755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MSG_RS11765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MSG_RS11770	COG1160	GTP binding
MSG_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS11830	COG0375	protein maturation
MSG_RS11840	COG0298	carbon dioxide binding
MSG_RS11845	COG0409	Hydrogenase expression formation protein
MSG_RS11855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MSG_RS11865	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MSG_RS11900	COG0066	3-isopropylmalate dehydratase activity
MSG_RS11905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MSG_RS11950	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS11955	COG2172	sigma factor antagonist activity
MSG_RS11955	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS11955	COG2208	phosphoserine phosphatase activity
MSG_RS11980	COG5001	Diguanylate cyclase
MSG_RS11980	COG5002	protein histidine kinase activity
MSG_RS11980	COG3447	MASE1 domain protein
MSG_RS12010	COG2271	Major facilitator Superfamily
MSG_RS12015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MSG_RS12020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MSG_RS12025	COG4208	sulfate ABC transporter
MSG_RS12170	COG1053	succinate dehydrogenase
MSG_RS12200	COG0346	lactoylglutathione lyase activity
MSG_RS12210	COG2267	carboxylic ester hydrolase activity
MSG_RS12235	COG0243	molybdopterin cofactor binding
MSG_RS12245	COG1755	Isoprenylcysteine carboxyl methyltransferase
MSG_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS12265	COG1716	ATPase activity
MSG_RS12265	COG0842	Transport permease protein
MSG_RS12265	COG1131	(ABC) transporter
MSG_RS12295	COG1960	acyl-CoA dehydrogenase activity
MSG_RS12300	COG1960	acyl-CoA dehydrogenase activity
MSG_RS12310	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MSG_RS12325	COG0657	acetylesterase activity
MSG_RS12330	COG2072	flavoprotein involved in K transport
MSG_RS12335	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS12350	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS12355	COG0235	Class ii aldolase
MSG_RS12475	COG0393	Putative heavy-metal-binding
MSG_RS12505	COG2813	Specifically methylates the guanine in position
MSG_RS12510	COG0513	Belongs to the DEAD box helicase family
MSG_RS12530	COG1053	succinate dehydrogenase
MSG_RS12535	COG4638	Rieske (2fe-2S)
MSG_RS12545	COG1024	Enoyl-CoA hydratase
MSG_RS12555	COG0022	dehydrogenase e1 component
MSG_RS12560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MSG_RS12565	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS12570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS12655	COG5651	PPE family
MSG_RS12665	COG5651	PPE family
MSG_RS12695	COG1404	Belongs to the peptidase S8 family
MSG_RS12745	COG1285	pathogenesis
MSG_RS12780	COG1053	succinate dehydrogenase
MSG_RS12870	COG2146	nitrite reductase [NAD(P)H] activity
MSG_RS12910	COG1253	flavin adenine dinucleotide binding
MSG_RS12915	COG1253	flavin adenine dinucleotide binding
MSG_RS12925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MSG_RS12945	COG0831	urea catabolic process
MSG_RS12950	COG0832	Belongs to the urease beta subunit family
MSG_RS12955	COG0804	urea catabolic process
MSG_RS12960	COG0830	nickel cation binding
MSG_RS12980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS13040	COG4221	oxidoreductase activity
MSG_RS13045	COG1968	undecaprenyl-diphosphatase activity
MSG_RS13050	COG0183	Belongs to the thiolase family
MSG_RS13115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MSG_RS13140	COG1024	Enoyl-CoA hydratase
MSG_RS13165	COG0174	glutamine synthetase
MSG_RS13190	COG0300	oxidoreductase activity
MSG_RS13200	COG1652	LysM domain
MSG_RS13250	COG2070	2-Nitropropane dioxygenase
MSG_RS13270	COG1063	alcohol dehydrogenase
MSG_RS13285	COG1490	D-aminoacyl-tRNA deacylase activity
MSG_RS13295	COG1058	Belongs to the CinA family
MSG_RS13295	COG1546	Belongs to the CinA family
MSG_RS13300	COG0477	Major facilitator Superfamily
MSG_RS13310	COG1950	PFAM Membrane protein of
MSG_RS13315	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS13350	COG2070	2-Nitropropane dioxygenase
MSG_RS13355	COG1942	4-Oxalocrotonate Tautomerase
MSG_RS13360	COG0583	DNA-binding transcription factor activity
MSG_RS13415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS13425	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS13490	COG0596	Alpha beta hydrolase
MSG_RS13505	COG1454	alcohol dehydrogenase
MSG_RS13510	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS13530	COG2130	NADP-dependent
MSG_RS13535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS13540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS13590	COG2226	methyltransferase
MSG_RS13600	COG3757	hydrolase, family 25
MSG_RS13650	COG0697	spore germination
MSG_RS13655	COG1819	glycosyl
MSG_RS13670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MSG_RS13680	COG0656	L-ascorbic acid biosynthetic process
MSG_RS13685	COG2301	Belongs to the HpcH HpaI aldolase family
MSG_RS13775	COG2267	carboxylic ester hydrolase activity
MSG_RS13780	COG1280	lysine exporter protein (LysE YggA)
MSG_RS13975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MSG_RS13995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MSG_RS13995	COG0392	lysyltransferase activity
MSG_RS14000	COG0375	protein maturation
MSG_RS14045	COG0298	carbon dioxide binding
MSG_RS14175	COG0531	amino acid
MSG_RS14180	COG0475	glutathione-regulated potassium exporter activity
MSG_RS14180	COG0569	domain protein
MSG_RS14200	COG0604	alcohol dehydrogenase
MSG_RS14215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MSG_RS14225	COG0667	Aldo Keto reductase
MSG_RS14250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS14275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MSG_RS14290	COG0477	Major facilitator Superfamily
MSG_RS14320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS14345	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MSG_RS14355	COG2837	iron assimilation
MSG_RS14360	COG2822	iron ion transport
MSG_RS14375	COG1752	Esterase of the alpha-beta hydrolase superfamily
MSG_RS14415	COG1953	Uracil, thiamine, allantoin
MSG_RS14425	COG4266	Belongs to the allantoicase family
MSG_RS14435	COG3842	ATPase activity
MSG_RS14440	COG0395	ABC-type sugar transport system, permease component
MSG_RS14445	COG1175	transmembrane transport
MSG_RS14480	COG1335	isochorismatase
MSG_RS14490	COG3265	gluconokinase activity
MSG_RS14500	COG2272	Belongs to the type-B carboxylesterase lipase family
MSG_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS14535	COG3321	synthase
MSG_RS14535	COG0604	alcohol dehydrogenase
MSG_RS14560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MSG_RS14645	COG0300	oxidoreductase activity
MSG_RS14730	COG2378	regulation of single-species biofilm formation
MSG_RS14740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MSG_RS14785	COG1550	Protein conserved in bacteria
MSG_RS14800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MSG_RS14830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS14900	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS14905	COG0215	cysteine-tRNA ligase activity
MSG_RS14910	COG1218	3'(2'),5'-bisphosphate nucleotidase
MSG_RS14945	COG0167	dihydroorotate dehydrogenase activity
MSG_RS14950	COG1403	HNH endonuclease
MSG_RS14965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MSG_RS15015	COG0667	Aldo Keto reductase
MSG_RS15030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS15035	COG2140	Oxalate decarboxylase
MSG_RS15075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MSG_RS15085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MSG_RS15090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MSG_RS15105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MSG_RS15150	COG0768	penicillin binding
MSG_RS15160	COG0275	rRNA processing
MSG_RS15190	COG0142	geranyltranstransferase activity
MSG_RS15210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS15215	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MSG_RS15245	COG0003	Pfam Anion-transporting ATPase
MSG_RS15260	COG1022	Amp-dependent synthetase and ligase
MSG_RS15290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MSG_RS15295	COG1845	cytochrome c oxidase, subunit III
MSG_RS15300	COG2010	Cytochrome c
MSG_RS15345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MSG_RS15380	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MSG_RS15390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MSG_RS15400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MSG_RS15425	COG1090	epimerase
MSG_RS15435	COG0321	lipoyl(octanoyl) transferase activity
MSG_RS15520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MSG_RS15590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MSG_RS15600	COG0596	Alpha beta hydrolase
MSG_RS15665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MSG_RS15730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MSG_RS15735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MSG_RS15750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS15875	COG0860	N-Acetylmuramoyl-L-alanine amidase
MSG_RS15980	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MSG_RS15995	COG0438	transferase activity, transferring glycosyl groups
MSG_RS16030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS16070	COG0596	Alpha beta hydrolase
MSG_RS16085	COG1218	3'(2'),5'-bisphosphate nucleotidase
MSG_RS16115	COG2239	Acts as a magnesium transporter
MSG_RS16195	COG1022	Amp-dependent synthetase and ligase
MSG_RS16200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MSG_RS16235	COG2205	protein histidine kinase activity
MSG_RS16240	COG0745	RESPONSE REGULATOR receiver
MSG_RS16255	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS16290	COG3415	Transposase
MSG_RS16290	COG2801	Transposase and inactivated derivatives
MSG_RS16295	COG3012	SEC-C Motif Domain Protein
MSG_RS16315	COG4585	Histidine kinase
MSG_RS16335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MSG_RS16345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS16405	COG1175	transmembrane transport
MSG_RS16410	COG0395	ABC-type sugar transport system, permease component
MSG_RS16420	COG0531	amino acid
MSG_RS16425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MSG_RS16430	COG1834	amidinotransferase
MSG_RS16435	COG1522	sequence-specific DNA binding
MSG_RS16465	COG1716	ATPase activity
MSG_RS16465	COG1131	(ABC) transporter
MSG_RS16465	COG0842	Transport permease protein
MSG_RS16475	COG2223	nitrite transmembrane transporter activity
MSG_RS16485	COG0243	molybdopterin cofactor binding
MSG_RS16495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MSG_RS16495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS16500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MSG_RS16530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MSG_RS16555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS16560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS16565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MSG_RS16570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MSG_RS16585	COG1045	serine acetyltransferase
MSG_RS16595	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
MSG_RS16600	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MSG_RS16605	COG0235	Class ii aldolase
MSG_RS16605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MSG_RS16680	COG1381	Involved in DNA repair and RecF pathway recombination
MSG_RS16690	COG3546	catalase activity
MSG_RS16700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MSG_RS16725	COG0484	heat shock protein binding
MSG_RS16730	COG1420	regulation of RNA biosynthetic process
MSG_RS16775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MSG_RS16795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MSG_RS16800	COG1021	2,3-dihydroxybenzoate-AMP ligase
MSG_RS16820	COG2072	flavoprotein involved in K transport
MSG_RS16830	COG1169	isochorismate synthase
MSG_RS16875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MSG_RS16880	COG4208	sulfate ABC transporter
MSG_RS16885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MSG_RS16890	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MSG_RS16900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS16905	COG3387	PFAM Glycoside hydrolase 15-related
MSG_RS16925	COG0517	IMP dehydrogenase activity
MSG_RS16935	COG1305	Transglutaminase-like
MSG_RS16965	COG1596	polysaccharide export
MSG_RS16965	COG1555	photosystem II stabilization
MSG_RS16970	COG1960	acyl-CoA dehydrogenase activity
MSG_RS16975	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17005	COG2755	lipolytic protein G-D-S-L family
MSG_RS17015	COG0799	negative regulation of ribosome biogenesis
MSG_RS17030	COG0542	response to heat
MSG_RS17035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MSG_RS17040	COG0668	transmembrane transport
MSG_RS17050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MSG_RS17055	COG2188	Transcriptional regulator
MSG_RS17060	COG2079	MmgE PrpD family protein
MSG_RS17070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MSG_RS17075	COG0066	3-isopropylmalate dehydratase activity
MSG_RS17080	COG1881	PFAM PEBP family protein
MSG_RS17085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MSG_RS17085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MSG_RS17140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MSG_RS17155	COG1530	ribonuclease E activity
MSG_RS17170	COG0285	dihydrofolate synthase activity
MSG_RS17180	COG3268	Saccharopine dehydrogenase
MSG_RS17185	COG1388	LysM domain
MSG_RS17195	COG1013	pyruvate-flavodoxin oxidoreductase activity
MSG_RS17200	COG0674	pyruvate-flavodoxin oxidoreductase activity
MSG_RS17200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MSG_RS17210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MSG_RS17215	COG0740	serine-type endopeptidase activity
MSG_RS17220	COG0740	serine-type endopeptidase activity
MSG_RS17240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS17260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MSG_RS17290	COG2346	COG2346, Truncated hemoglobins
MSG_RS17295	COG0366	Alpha amylase catalytic
MSG_RS17315	COG2902	Dehydrogenase
MSG_RS17325	COG0629	single-stranded DNA binding
MSG_RS17355	COG0657	acetylesterase activity
MSG_RS17390	COG3119	arylsulfatase activity
MSG_RS17410	COG3415	Transposase
MSG_RS17410	COG2801	Transposase and inactivated derivatives
MSG_RS17455	COG2030	dehydratase
MSG_RS17460	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MSG_RS17490	COG0300	oxidoreductase activity
MSG_RS17495	COG0433	COG0433 Predicted ATPase
MSG_RS17520	COG1376	ErfK ybiS ycfS ynhG family protein
MSG_RS17540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MSG_RS17545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MSG_RS17550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MSG_RS17585	COG0628	permease
MSG_RS17630	COG0736	holo-[acyl-carrier-protein] synthase activity
MSG_RS17645	COG3757	hydrolase, family 25
MSG_RS17725	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17730	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17735	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MSG_RS17780	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17785	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17790	COG0657	acetylesterase activity
MSG_RS17810	COG2124	cytochrome p450
MSG_RS17850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MSG_RS17865	COG2072	flavoprotein involved in K transport
MSG_RS17880	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS17885	COG2124	cytochrome p450
MSG_RS17915	COG1937	Protein conserved in bacteria
MSG_RS17920	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17945	COG1024	Enoyl-CoA hydratase
MSG_RS17960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MSG_RS17965	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS17990	COG1960	acyl-CoA dehydrogenase activity
MSG_RS17995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS18000	COG0183	Belongs to the thiolase family
MSG_RS18010	COG1960	acyl-CoA dehydrogenase activity
MSG_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS18020	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MSG_RS18070	COG2123	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MSG_RS18075	COG1234	tRNA 3'-trailer cleavage
MSG_RS18080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MSG_RS18105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MSG_RS18115	COG0058	SHG alpha-glucan phosphorylase activity
MSG_RS18125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MSG_RS18140	COG0346	lactoylglutathione lyase activity
MSG_RS18150	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MSG_RS18195	COG2030	dehydratase
MSG_RS18205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MSG_RS18225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MSG_RS18260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MSG_RS18260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MSG_RS18270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MSG_RS18275	COG0356	it plays a direct role in the translocation of protons across the membrane
MSG_RS18290	COG0009	L-threonylcarbamoyladenylate synthase
MSG_RS18295	COG2890	protein-(glutamine-N5) methyltransferase activity
MSG_RS18300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MSG_RS18310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MSG_RS18320	COG0083	homoserine kinase activity
MSG_RS18330	COG0460	homoserine dehydrogenase
MSG_RS18335	COG0019	diaminopimelate decarboxylase activity
MSG_RS18340	COG0018	arginyl-trna synthetase
MSG_RS18375	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS18420	COG0494	nUDIX hydrolase
MSG_RS18455	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MSG_RS18455	COG3261	NADH dehydrogenase
MSG_RS18460	COG0651	ATP synthesis coupled electron transport
MSG_RS18470	COG0650	Formate hydrogenlyase subunit 4
MSG_RS18480	COG3260	NADH ubiquinone oxidoreductase 20
MSG_RS18595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS18620	COG0277	FAD linked oxidase domain protein
MSG_RS18625	COG0574	Belongs to the PEP-utilizing enzyme family
MSG_RS18625	COG3848	Pyruvate phosphate dikinase
MSG_RS18705	COG0508	dehydrogenase complex catalyzes the overall conversion of
MSG_RS18705	COG0567	Dehydrogenase, E1 component
MSG_RS18725	COG0039	L-malate dehydrogenase activity
MSG_RS18730	COG0598	Magnesium transport protein CorA
MSG_RS18770	COG2239	Acts as a magnesium transporter
MSG_RS18795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MSG_RS18800	COG5662	AntiSigma factor
MSG_RS18815	COG1309	transcriptional regulator
MSG_RS18820	COG1131	(ABC) transporter
MSG_RS18825	COG3559	Exporter of polyketide antibiotics
MSG_RS18855	COG0519	Catalyzes the synthesis of GMP from XMP
MSG_RS18865	COG0463	Glycosyl transferase, family 2
MSG_RS18870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MSG_RS18880	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS18885	COG1611	Belongs to the LOG family
MSG_RS18910	COG0477	Major facilitator Superfamily
MSG_RS18915	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS18925	COG2124	cytochrome p450
MSG_RS18940	COG2124	cytochrome p450
MSG_RS18945	COG1960	acyl-CoA dehydrogenase activity
MSG_RS18960	COG1960	acyl-CoA dehydrogenase activity
MSG_RS18975	COG1309	transcriptional regulator
MSG_RS18985	COG0506	proline dehydrogenase activity
MSG_RS18990	COG1012	belongs to the aldehyde dehydrogenase family
MSG_RS18995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MSG_RS18995	COG2508	Transcriptional regulator
MSG_RS19015	COG4424	Sulfotransferase
MSG_RS19035	COG2855	membrane
MSG_RS19045	COG5651	PPE family
MSG_RS19050	COG2409	Drug exporters of the RND superfamily
MSG_RS19060	COG3321	synthase
MSG_RS19060	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS19060	COG0604	alcohol dehydrogenase
MSG_RS19065	COG0657	acetylesterase activity
MSG_RS19070	COG0531	amino acid
MSG_RS19080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MSG_RS19090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MSG_RS19100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MSG_RS19115	COG1217	gtp-binding protein TYPA
MSG_RS19165	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MSG_RS19175	COG3467	pyridoxamine 5'-phosphate
MSG_RS19185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS19190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS19210	COG2409	Drug exporters of the RND superfamily
MSG_RS19220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS19225	COG1024	Enoyl-CoA hydratase
MSG_RS19230	COG0702	epimerase
MSG_RS19240	COG0702	epimerase
MSG_RS19250	COG1755	Isoprenylcysteine carboxyl methyltransferase
MSG_RS19260	COG1024	Enoyl-CoA hydratase
MSG_RS19265	COG0183	Belongs to the thiolase family
MSG_RS19275	COG1960	acyl-CoA dehydrogenase activity
MSG_RS19280	COG1960	acyl-CoA dehydrogenase activity
MSG_RS19285	COG1309	transcriptional regulator
MSG_RS19300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MSG_RS19320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MSG_RS19330	COG3800	Transcriptional regulator
MSG_RS19330	COG1396	sequence-specific DNA binding
MSG_RS19340	COG1403	HNH endonuclease
MSG_RS19350	COG0574	Belongs to the PEP-utilizing enzyme family
MSG_RS19350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MSG_RS19405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MSG_RS19430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MSG_RS19455	COG3415	Transposase
MSG_RS19455	COG2801	Transposase and inactivated derivatives
MSG_RS19495	COG0012	GTP binding
MSG_RS19505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MSG_RS19515	COG1570	exodeoxyribonuclease VII activity
MSG_RS19520	COG1722	exodeoxyribonuclease VII activity
MSG_RS19565	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MSG_RS19575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MSG_RS19580	COG0572	uridine kinase
MSG_RS19595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MSG_RS19610	COG1331	Highly conserved protein containing a thioredoxin domain
MSG_RS19650	COG0657	acetylesterase activity
MSG_RS19655	COG2755	lipolytic protein G-D-S-L family
MSG_RS19660	COG0183	Belongs to the thiolase family
MSG_RS19670	COG1024	Enoyl-CoA hydratase
MSG_RS19715	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS19720	COG3391	amine dehydrogenase activity
MSG_RS19760	COG5651	PPE family
MSG_RS19790	COG0745	RESPONSE REGULATOR receiver
MSG_RS19795	COG2205	protein histidine kinase activity
MSG_RS19810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MSG_RS19815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MSG_RS19855	COG3956	TIGRFAM MazG family protein
MSG_RS19890	COG1393	Belongs to the ArsC family
MSG_RS19910	COG0193	aminoacyl-tRNA hydrolase activity
MSG_RS19915	COG2207	Transcriptional regulator
MSG_RS19925	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS19945	COG0084	hydrolase, TatD family'
MSG_RS19980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MSG_RS20005	COG0438	transferase activity, transferring glycosyl groups
MSG_RS20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MSG_RS20045	COG0489	protein tyrosine kinase activity
MSG_RS20115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MSG_RS20115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MSG_RS20120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MSG_RS20125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MSG_RS20130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MSG_RS20145	COG0701	Predicted permease
MSG_RS20155	COG2200	EAL domain
MSG_RS20155	COG3287	FIST C domain
MSG_RS20155	COG2199	diguanylate cyclase activity
MSG_RS20195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MSG_RS20200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MSG_RS20215	COG1970	mechanosensitive ion channel activity
MSG_RS20220	COG0521	Mo-molybdopterin cofactor biosynthetic process
MSG_RS20220	COG0315	cyclic pyranopterin monophosphate synthase activity
MSG_RS20225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MSG_RS20235	COG2205	protein histidine kinase activity
MSG_RS20255	COG1960	acyl-CoA dehydrogenase activity
MSG_RS20260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MSG_RS20275	COG1024	Enoyl-CoA hydratase
MSG_RS20315	COG0138	bifunctional purine biosynthesis protein purh
MSG_RS20355	COG0739	heme binding
MSG_RS20400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MSG_RS20450	COG0246	Mannitol dehydrogenase
MSG_RS20455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MSG_RS20460	COG0246	Mannitol dehydrogenase
MSG_RS20475	COG0581	inorganic phosphate transmembrane transporter activity
MSG_RS20500	COG1914	H( )-stimulated, divalent metal cation uptake system
MSG_RS20510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS20645	COG0596	Alpha beta hydrolase
MSG_RS20695	COG3629	intracellular signal transduction
MSG_RS20695	COG3903	Transcriptional regulator
MSG_RS20700	COG0259	pyridoxamine-phosphate oxidase activity
MSG_RS20725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MSG_RS20775	COG0435	Glutathione S-transferase
MSG_RS20780	COG1278	Cold shock
MSG_RS20790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MSG_RS20830	COG1061	Type III restriction enzyme res subunit
MSG_RS20835	COG2186	Transcriptional regulator
MSG_RS20845	COG0154	amidase activity
MSG_RS20850	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MSG_RS20880	COG0183	Belongs to the thiolase family
MSG_RS20890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MSG_RS20910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS20930	COG2813	Specifically methylates the guanine in position
MSG_RS20950	COG1024	Enoyl-CoA hydratase
MSG_RS20950	COG1250	3-hydroxyacyl-CoA dehydrogenase
MSG_RS20955	COG0183	Belongs to the thiolase family
MSG_RS20975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS20985	COG3961	Belongs to the TPP enzyme family
MSG_RS21010	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS21025	COG1024	Enoyl-CoA hydratase
MSG_RS21035	COG1309	transcriptional regulator
MSG_RS21065	COG1309	transcriptional regulator
MSG_RS21100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MSG_RS21125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS21130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS21135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS21140	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS21150	COG2124	cytochrome p450
MSG_RS21155	COG1960	acyl-CoA dehydrogenase activity
MSG_RS21180	COG2205	protein histidine kinase activity
MSG_RS21220	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MSG_RS21245	COG2084	Dehydrogenase
MSG_RS21250	COG2124	cytochrome p450
MSG_RS21270	COG2124	cytochrome p450
MSG_RS21285	COG0183	Belongs to the thiolase family
MSG_RS21310	COG4638	Rieske (2fe-2S)
MSG_RS21320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MSG_RS21330	COG1960	acyl-CoA dehydrogenase activity
MSG_RS21355	COG1960	acyl-CoA dehydrogenase activity
MSG_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS21375	COG1846	Transcriptional regulator
MSG_RS21385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS21395	COG0006	proline dipeptidase activity
MSG_RS21430	COG2132	Multicopper oxidase
MSG_RS21455	COG1053	succinate dehydrogenase
MSG_RS21460	COG3384	dioxygenase
MSG_RS21465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS21470	COG2267	carboxylic ester hydrolase activity
MSG_RS21480	COG1053	succinate dehydrogenase
MSG_RS21485	COG4585	Histidine kinase
MSG_RS21495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MSG_RS21505	COG0596	Alpha beta hydrolase
MSG_RS21515	COG1024	Enoyl-CoA hydratase
MSG_RS21520	COG1960	acyl-CoA dehydrogenase activity
MSG_RS21525	COG1960	acyl-CoA dehydrogenase activity
MSG_RS21535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MSG_RS21545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MSG_RS21550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS21555	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MSG_RS21560	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MSG_RS21560	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MSG_RS21590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MSG_RS21635	COG0640	Transcriptional regulator
MSG_RS21675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MSG_RS21680	COG0581	inorganic phosphate transmembrane transporter activity
MSG_RS21690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MSG_RS21700	COG0745	RESPONSE REGULATOR receiver
MSG_RS21735	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MSG_RS21755	COG0354	folic acid binding
MSG_RS21765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MSG_RS21800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MSG_RS21825	COG1362	aminopeptidase activity
MSG_RS21830	COG2837	iron assimilation
MSG_RS21840	COG2258	MOSC domain
MSG_RS21845	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS21850	COG0596	Alpha beta hydrolase
MSG_RS21865	COG0604	alcohol dehydrogenase
MSG_RS21865	COG3321	synthase
MSG_RS21865	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS21910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MSG_RS21935	COG0477	Major facilitator Superfamily
MSG_RS21960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MSG_RS22020	COG4221	oxidoreductase activity
MSG_RS22025	COG2124	cytochrome p450
MSG_RS22060	COG2205	protein histidine kinase activity
MSG_RS22065	COG0745	RESPONSE REGULATOR receiver
MSG_RS22110	COG1305	Transglutaminase-like
MSG_RS22125	COG0596	Alpha beta hydrolase
MSG_RS22155	COG1024	Enoyl-CoA hydratase
MSG_RS22205	COG1316	TRANSCRIPTIONal
MSG_RS22220	COG1024	Enoyl-CoA hydratase
MSG_RS22225	COG3599	regulation of cell shape
MSG_RS22260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MSG_RS22285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MSG_RS22295	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS22305	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22310	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22315	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS22325	COG0028	Belongs to the TPP enzyme family
MSG_RS22365	COG1024	Enoyl-CoA hydratase
MSG_RS22375	COG2124	cytochrome p450
MSG_RS22385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS22415	COG4638	Rieske (2fe-2S)
MSG_RS22430	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS22445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MSG_RS22450	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MSG_RS22455	COG3971	2-oxopent-4-enoate hydratase activity
MSG_RS22460	COG1053	succinate dehydrogenase
MSG_RS22465	COG2030	dehydratase
MSG_RS22485	COG2030	dehydratase
MSG_RS22490	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22495	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22500	COG2124	cytochrome p450
MSG_RS22505	COG0183	Belongs to the thiolase family
MSG_RS22525	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS22530	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS22535	COG1024	Enoyl-CoA hydratase
MSG_RS22560	COG0183	Belongs to the thiolase family
MSG_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS22575	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22580	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS22585	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22590	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22595	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22600	COG0436	Aminotransferase
MSG_RS22605	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS22655	COG1960	acyl-CoA dehydrogenase activity
MSG_RS22660	COG1309	transcriptional regulator
MSG_RS22665	COG1609	Transcriptional regulator
MSG_RS22675	COG1116	anion transmembrane transporter activity
MSG_RS22705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MSG_RS22720	COG0215	cysteine-tRNA ligase activity
MSG_RS22730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MSG_RS22735	COG1329	Transcriptional regulator
MSG_RS22770	COG2267	carboxylic ester hydrolase activity
MSG_RS22825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MSG_RS22855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MSG_RS22860	COG0302	gtp cyclohydrolase
MSG_RS22875	COG2267	carboxylic ester hydrolase activity
MSG_RS22920	COG2027	D-alanyl-D-alanine carboxypeptidase
MSG_RS22975	COG0470	DNA polymerase III
MSG_RS23000	COG1111	helicase
MSG_RS23000	COG1205	dead DEAH box helicase
MSG_RS23060	COG4172	Belongs to the ABC transporter superfamily
MSG_RS23065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MSG_RS23070	COG0601	transmembrane transport
MSG_RS23125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MSG_RS23140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MSG_RS23175	COG1408	metallophosphoesterase
MSG_RS23180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MSG_RS23225	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS23230	COG1366	Belongs to the anti-sigma-factor antagonist family
MSG_RS23235	COG2172	sigma factor antagonist activity
MSG_RS23260	COG2890	protein-(glutamine-N5) methyltransferase activity
MSG_RS23265	COG0693	protein deglycase activity
MSG_RS23270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MSG_RS23295	COG0714	Associated with various cellular activities
MSG_RS23320	COG1695	Transcriptional regulator
MSG_RS23325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MSG_RS23335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MSG_RS23345	COG0121	glutamine amidotransferase
MSG_RS23350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MSG_RS23365	COG1764	response to oxidative stress
MSG_RS23405	COG1403	HNH endonuclease
MSG_RS23420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MSG_RS23425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MSG_RS23445	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MSG_RS23450	COG0860	N-Acetylmuramoyl-L-alanine amidase
MSG_RS23465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS23480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MSG_RS23515	COG1113	amino acid transport
MSG_RS23605	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS23640	COG1793	dna ligase
MSG_RS23655	COG1051	belongs to the nudix hydrolase family
MSG_RS23680	COG3804	dihydrodipicolinate reductase
MSG_RS23700	COG0640	Transcriptional regulator
MSG_RS23705	COG0798	PFAM Bile acid sodium symporter
MSG_RS23710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MSG_RS23795	COG0590	tRNA wobble adenosine to inosine editing
MSG_RS23805	COG0287	Prephenate dehydrogenase
MSG_RS23825	COG0517	IMP dehydrogenase activity
MSG_RS23825	COG1125	glycine betaine transport
MSG_RS23835	COG5416	Lipopolysaccharide assembly protein A domain
MSG_RS23885	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MSG_RS23895	COG2205	protein histidine kinase activity
MSG_RS23900	COG0745	RESPONSE REGULATOR receiver
MSG_RS23925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MSG_RS23935	COG0656	L-ascorbic acid biosynthetic process
MSG_RS23940	COG1309	transcriptional regulator
MSG_RS24000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MSG_RS24020	COG0604	alcohol dehydrogenase
MSG_RS24055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MSG_RS24070	COG2268	Band 7 protein
MSG_RS24085	COG0277	FAD linked oxidase domain protein
MSG_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
MSG_RS24135	COG1716	ATPase activity
MSG_RS24145	COG1960	acyl-CoA dehydrogenase activity
MSG_RS24155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MSG_RS24160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MSG_RS24165	COG3321	synthase
MSG_RS24165	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MSG_RS24165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MSG_RS24170	COG0318	PFAM AMP-dependent synthetase and ligase
MSG_RS24175	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MSG_RS24180	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MSG_RS24190	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MSG_RS24205	COG1216	Glycosyl transferase, family 2
MSG_RS24225	COG0561	phosphatase activity
MSG_RS24240	COG0204	Acyl-transferase
MSG_RS24275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MSG_RS24310	COG1316	TRANSCRIPTIONal
MSG_RS24340	COG2119	membrane
MSG_RS24395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MSG_RS24395	COG1796	DNA polymerase
MSG_RS24425	COG0069	glutamate synthase activity
MSG_RS24425	COG0067	glutamate synthase
MSG_RS24425	COG0070	glutamate synthase
MSG_RS24440	COG0702	epimerase
MSG_RS24505	COG4842	Belongs to the WXG100 family
MSG_RS24510	COG4842	Belongs to the WXG100 family
MSG_RS24580	COG1404	Belongs to the peptidase S8 family
MSG_RS24585	COG0464	growth
MSG_RS24595	COG1404	Belongs to the peptidase S8 family
MSG_RS24605	COG2894	cell division
MSG_RS24630	COG0617	tRNA 3'-terminal CCA addition
MSG_RS24650	COG1595	DNA-templated transcription, initiation
MSG_RS24670	COG0860	N-Acetylmuramoyl-L-alanine amidase
MSG_RS24670	COG3409	Peptidoglycan-binding domain 1 protein
MSG_RS24685	COG1192	Involved in chromosome partitioning
MSG_RS24690	COG0357	Ribosomal RNA small subunit methyltransferase G
MSG_RS24700	COG0706	membrane insertase activity