MSG_RS01765 875d98c00ac1979b0a2dfbaf36f5ed00 184 Gene3D G3DSA:3.10.450.50 20 182 8.4E-4 T 29-03-2018 MSG_RS15065 5a157667c4aded3d44f1a01368a7aa2c 264 SUPERFAMILY SSF51419 14 257 3.4E-55 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS15065 5a157667c4aded3d44f1a01368a7aa2c 264 Pfam PF01168 Alanine racemase, N-terminal domain 22 259 1.1E-13 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS15065 5a157667c4aded3d44f1a01368a7aa2c 264 PIRSF PIRSF004848 11 264 3.5E-63 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MSG_RS15065 5a157667c4aded3d44f1a01368a7aa2c 264 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 103 117 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MSG_RS15065 5a157667c4aded3d44f1a01368a7aa2c 264 Gene3D G3DSA:3.20.20.10 7 263 1.2E-49 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS06820 b74080552ac4bf8fd082abc7e4939fde 367 Gene3D G3DSA:2.60.120.10 62 158 4.0E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS06820 b74080552ac4bf8fd082abc7e4939fde 367 Gene3D G3DSA:2.60.120.10 159 350 2.0E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS06820 b74080552ac4bf8fd082abc7e4939fde 367 SUPERFAMILY SSF51182 43 357 6.51E-70 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS06820 b74080552ac4bf8fd082abc7e4939fde 367 Pfam PF04209 homogentisate 1,2-dioxygenase 103 291 1.8E-9 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 SUPERFAMILY SSF55073 134 315 2.83E-22 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 SMART SM00240 29 85 4.1E-6 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 Gene3D G3DSA:3.30.70.1230 125 320 8.3E-20 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 Gene3D G3DSA:2.60.200.20 1 124 7.2E-20 T 29-03-2018 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 Pfam PF00498 FHA domain 32 102 1.4E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 134 310 2.0E-8 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS12055 00ef92c2bd2fc3daf5cdef29c406f87c 353 SUPERFAMILY SSF49879 11 110 8.61E-20 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 Pfam PF00574 Clp protease 27 203 7.2E-74 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 204 38.049 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 1.4E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 1.4E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 1.4E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 1.4E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 1.4E-41 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 29-03-2018 IPR033135 ClpP, histidine active site MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 Gene3D G3DSA:3.90.226.10 11 205 8.5E-38 T 29-03-2018 MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 29-03-2018 IPR018215 ClpP, Ser active site MSG_RS17215 9fa3b60c3bd718e144f178c505e93334 211 SUPERFAMILY SSF52096 21 205 1.76E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04690 6e776e35d4743d94d4a7b2a0bd3fa8a6 304 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 6.8E-66 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS04690 6e776e35d4743d94d4a7b2a0bd3fa8a6 304 Gene3D G3DSA:3.40.50.150 1 299 1.6E-57 T 29-03-2018 MSG_RS04690 6e776e35d4743d94d4a7b2a0bd3fa8a6 304 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 283 5.4E-84 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS04690 6e776e35d4743d94d4a7b2a0bd3fa8a6 304 SUPERFAMILY SSF53335 15 292 1.94E-79 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 Gene3D G3DSA:3.40.50.300 252 420 2.6E-25 T 29-03-2018 MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 Pfam PF00270 DEAD/DEAH box helicase 25 212 2.0E-24 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 Pfam PF08494 DEAD/H associated 664 853 1.6E-72 T 29-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SMART SM00382 37 389 5.9E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 Gene3D G3DSA:3.40.50.300 5 231 3.2E-36 T 29-03-2018 MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 Pfam PF00271 Helicase conserved C-terminal domain 334 402 1.7E-12 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SMART SM00490 289 402 1.7E-13 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SMART SM00487 20 244 3.5E-34 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SUPERFAMILY SSF52540 333 406 1.96E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SUPERFAMILY SSF52540 34 214 1.96E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05645 6c26ba8378e8e706bf6505f96d9b18d0 1522 SUPERFAMILY SSF52540 242 297 1.96E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06400 51a13749394d87ba39dc11dc9e95c4b2 127 SUPERFAMILY SSF54909 33 115 5.01E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS06400 51a13749394d87ba39dc11dc9e95c4b2 127 Pfam PF07045 Domain of unknown function (DUF1330) 39 116 6.3E-11 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 MSG_RS06400 51a13749394d87ba39dc11dc9e95c4b2 127 Gene3D G3DSA:3.30.70.100 1 127 2.2E-35 T 29-03-2018 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Gene3D G3DSA:1.20.140.10 223 391 3.5E-43 T 29-03-2018 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 2.9E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 121 4.1E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 SUPERFAMILY SSF56645 1 241 4.19E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 383 5.2E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Gene3D G3DSA:1.10.540.10 1 123 4.9E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 Gene3D G3DSA:2.40.110.10 124 222 1.7E-33 T 29-03-2018 MSG_RS12295 d6a9554dfac40e73f5a7d59e0556f811 392 SUPERFAMILY SSF47203 230 388 8.86E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Gene3D G3DSA:3.40.50.980 140 287 1.2E-42 T 29-03-2018 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Gene3D G3DSA:3.40.50.980 18 139 5.6E-19 T 29-03-2018 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 463 4.7E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 SUPERFAMILY SSF56801 20 471 8.77E-114 T 29-03-2018 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Gene3D G3DSA:2.30.38.10 288 373 6.1E-27 T 29-03-2018 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Gene3D G3DSA:3.30.300.30 375 472 5.0E-27 T 29-03-2018 MSG_RS18915 5fcd1f0b830f68dd1389ee5075a53440 473 Pfam PF00501 AMP-binding enzyme 45 374 8.7E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.4E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 233 8.1E-59 T 29-03-2018 MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 SUPERFAMILY SSF51735 2 234 6.04E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 171 1.2E-4 T 29-03-2018 MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 Gene3D G3DSA:3.40.50.720 1 236 4.1E-74 T 29-03-2018 MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 6.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 6.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21140 17b8201a4c35394ec6e6ed649bf71145 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 6.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 SUPERFAMILY SSF46894 285 372 2.55E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 SUPERFAMILY SSF69618 11 277 1.83E-53 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 Gene3D G3DSA:3.40.50.10090 43 171 1.1E-19 T 29-03-2018 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 Gene3D G3DSA:3.40.50.10090 172 273 7.9E-12 T 29-03-2018 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 268 1.3E-39 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 Pfam PF00486 Transcriptional regulatory protein, C terminal 306 372 8.6E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 Gene3D G3DSA:1.10.10.10 274 379 4.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02250 f54bd513611004e8a885f67d23b45556 381 SMART SM00862 301 372 1.9E-13 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Pfam PF00501 AMP-binding enzyme 26 395 2.2E-60 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 405 481 2.3E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Gene3D G3DSA:3.30.300.30 390 496 2.7E-18 T 29-03-2018 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Gene3D G3DSA:3.40.50.980 14 160 1.3E-22 T 29-03-2018 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Gene3D G3DSA:2.30.38.10 317 389 2.0E-18 T 29-03-2018 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 SUPERFAMILY SSF56801 24 493 2.88E-103 T 29-03-2018 MSG_RS22315 2bf7d2e0f085ff5106195a946911a115 503 Gene3D G3DSA:3.40.50.980 161 315 4.9E-33 T 29-03-2018 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 Gene3D G3DSA:1.10.1040.10 174 294 9.4E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 SUPERFAMILY SSF48179 164 292 1.02E-37 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 SUPERFAMILY SSF51735 6 163 1.97E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 291 7.0E-37 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 Gene3D G3DSA:3.40.50.720 1 173 2.0E-35 T 29-03-2018 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 162 8.7E-49 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 PIRSF PIRSF000103 1 294 1.2E-82 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 9 292 3.9E-111 T 29-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 MSG_RS04740 7e4bc72099b89dd69e434bfdc87eee51 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS12030 b6e3f71d5ad06997c5958a2b3939af15 228 Gene3D G3DSA:3.90.70.10 67 228 3.1E-16 T 29-03-2018 MSG_RS12030 b6e3f71d5ad06997c5958a2b3939af15 228 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 54 223 2.0E-33 T 29-03-2018 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 SUPERFAMILY SSF54999 5 100 3.53E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.326 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 3.4E-34 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 SMART SM01403 7 101 1.7E-54 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.2E-45 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04455 eb57eff24af29fb609c9c143b5107054 101 Gene3D G3DSA:3.30.70.600 4 101 1.9E-34 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MSG_RS19430 b64ff20d883146d2f6ad690aa991baab 123 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 117 4.9E-18 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS19430 b64ff20d883146d2f6ad690aa991baab 123 SUPERFAMILY SSF69118 3 120 9.55E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS19430 b64ff20d883146d2f6ad690aa991baab 123 Gene3D G3DSA:1.20.1290.10 10 123 5.6E-27 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 SUPERFAMILY SSF82866 161 359 5.75E-26 T 29-03-2018 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 SUPERFAMILY SSF82866 731 940 2.75E-27 T 29-03-2018 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 TIGRFAM TIGR00833 actII: transport protein 29 940 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 Pfam PF03176 MMPL family 621 948 2.0E-102 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 Pfam PF03176 MMPL family 63 393 3.7E-112 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 Gene3D G3DSA:1.20.1640.10 738 937 3.1E-25 T 29-03-2018 MSG_RS03290 067e1f9adba04c14c3f89c8cef06cfec 991 Gene3D G3DSA:1.20.1640.10 149 373 7.9E-28 T 29-03-2018 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:2.40.110.10 125 211 0.007 T 29-03-2018 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:1.10.540.10 354 483 6.9E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 SUPERFAMILY SSF56645 1 202 4.32E-22 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 595 735 2.7E-9 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 340 1.3E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:1.10.540.10 1 119 3.5E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 488 582 1.5E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 98 5.6E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 373 484 4.6E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:2.40.110.10 484 581 1.7E-32 T 29-03-2018 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 SUPERFAMILY SSF47203 595 738 9.99E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:1.20.140.10 225 342 1.4E-20 T 29-03-2018 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 SUPERFAMILY SSF47203 225 356 3.22E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 Gene3D G3DSA:1.20.140.10 582 741 9.1E-25 T 29-03-2018 MSG_RS00795 72f693f53b69b7ea5f6f4ac92561a6de 741 SUPERFAMILY SSF56645 365 605 4.06E-55 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SMART SM00478 326 483 4.3E-28 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Pfam PF02805 Metal binding domain of Ada 8 71 8.5E-28 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 322 465 1.1E-5 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SUPERFAMILY SSF48150 306 480 5.93E-39 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SUPERFAMILY SSF55945 201 297 5.96E-22 T 29-03-2018 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SMART SM01009 201 316 3.0E-44 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:1.10.340.30 315 433 3.5E-20 T 29-03-2018 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:1.10.10.60 82 137 0.0076 T 29-03-2018 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:3.30.310.20 201 314 1.1E-31 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:1.10.1670.10 435 487 1.7E-14 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Pfam PF06029 AlkA N-terminal domain 201 316 5.1E-27 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SMART SM00342 100 183 2.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:1.10.10.60 138 195 6.1E-8 T 29-03-2018 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Gene3D G3DSA:3.40.10.10 2 73 1.9E-23 T 29-03-2018 IPR035451 Ada-like domain MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SUPERFAMILY SSF57884 3 82 1.05E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 Pfam PF12833 Helix-turn-helix domain 106 185 2.9E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS18200 e2e550f940d27eb55a7a8cf88e3e5955 495 SUPERFAMILY SSF46689 137 185 1.48E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 Gene3D G3DSA:3.40.50.1820 1 290 4.0E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 2.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 2.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 2.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 Pfam PF12697 Alpha/beta hydrolase family 36 278 7.9E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12210 80033623bd18e08ad69e9110525a675c 290 SUPERFAMILY SSF53474 16 288 2.16E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 Gene3D G3DSA:1.10.540.10 1 113 7.1E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 SUPERFAMILY SSF47203 210 345 1.08E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 SUPERFAMILY SSF56645 1 191 5.64E-19 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 326 4.3E-20 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 99 1.0E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17725 f5e7845f453cfa20a2260aa391139520 356 Gene3D G3DSA:1.20.140.10 208 331 4.9E-28 T 29-03-2018 MSG_RS18850 1a52f519102e620de108a4c216a74c3f 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 1.2E-28 T 29-03-2018 IPR021465 Protein of unknown function DUF3117 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 Gene3D G3DSA:3.40.47.10 220 396 4.2E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 SUPERFAMILY SSF53901 7 230 3.46E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 SUPERFAMILY SSF53901 281 389 5.46E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 PIRSF PIRSF000429 1 400 3.0E-37 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 Pfam PF00108 Thiolase, N-terminal domain 25 224 8.6E-9 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS11310 aedcfda145da4e27040cc70d846f819d 400 Gene3D G3DSA:3.40.47.10 1 219 2.6E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF50249 651 720 6.12E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 266 342 2.2E-21 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF03725 3' exoribonuclease family, domain 2 150 232 4.9E-6 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF54211 6 147 2.08E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF00575 S1 RNA binding domain 651 720 2.8E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF46915 263 343 1.6E-18 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 13 722 2.9E-265 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 2 721 0.0 T 29-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Gene3D G3DSA:2.40.50.140 647 726 1.1E-17 T 29-03-2018 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SMART SM00322 582 647 1.4E-12 T 29-03-2018 IPR004087 K Homology domain GO:0003676 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF54211 317 518 6.07E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Gene3D G3DSA:3.30.230.70 14 276 2.5E-48 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 PIRSF PIRSF005499 3 748 6.8E-290 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SMART SM00316 652 723 2.9E-17 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF55666 473 576 1.3E-22 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF00013 KH domain 586 643 1.2E-10 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Gene3D G3DSA:3.30.1370.10 578 646 1.7E-14 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Gene3D G3DSA:3.30.230.70 335 577 1.0E-51 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF55666 148 258 2.14E-26 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 SUPERFAMILY SSF54791 586 671 1.35E-18 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Gene3D G3DSA:1.10.10.400 277 334 5.9E-24 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 5 726 27.034 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF01138 3' exoribonuclease family, domain 1 16 147 3.1E-17 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS08630 8231fa312667060e6dfaa57eaba01119 751 Pfam PF01138 3' exoribonuclease family, domain 1 347 479 9.8E-18 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 Pfam PF01381 Helix-turn-helix 50 103 8.0E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 SMART SM00530 49 104 1.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 Gene3D G3DSA:1.10.3100.10 40 141 5.5E-16 T 29-03-2018 IPR027910 YdiL-like domain MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 Pfam PF06114 IrrE N-terminal-like domain 228 350 1.5E-18 T 29-03-2018 IPR010359 IrrE N-terminal-like domain MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 SUPERFAMILY SSF47413 43 108 2.15E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 351 507 1.8E-65 T 29-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator MSG_RS19330 ea9a5424266f4a340eb922cb8773eab6 514 PIRSF PIRSF019251 38 512 1.2E-172 T 29-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 MSG_RS16575 fa37ae27355d75a55cccec6660c70d14 421 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 103 155 2.9E-14 T 29-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA MSG_RS16575 fa37ae27355d75a55cccec6660c70d14 421 Gene3D G3DSA:2.60.120.260 115 280 4.0E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 201 217 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00829 1363 1662 6.5E-167 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.30.70.250 700 747 6.2E-15 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF51735 1458 1603 3.54E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 569 863 5.0E-116 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 413 5.2E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1683 1863 2.7E-65 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF08659 KR domain 1683 1861 5.4E-62 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00826 929 1090 2.5E-80 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.40.47.10 31 300 1.2E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.10.129.10 930 1056 4.3E-6 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 288 3.3E-89 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF53901 37 410 2.34E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF50129 1361 1496 6.7E-24 T 29-03-2018 IPR011032 GroES-like MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 416 533 7.8E-14 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF13602 Zinc-binding dehydrogenase 1534 1662 8.0E-19 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF52151 758 856 3.92E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF52151 565 694 3.92E-69 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:1.10.1200.10 1960 2065 3.0E-19 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF14765 Polyketide synthase dehydratase 929 1199 3.0E-54 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF00698 Acyl transferase domain 567 882 1.4E-90 T 29-03-2018 IPR014043 Acyl transferase MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF51735 1213 1344 1.97E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.40.50.720 1676 1931 2.2E-52 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.40.47.10 303 464 1.9E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF55048 693 757 5.62E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM01294 1969 2036 2.1E-4 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF00550 Phosphopantetheine attachment site 1971 2036 5.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF47336 1962 2045 1.13E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SUPERFAMILY SSF51735 1679 1902 1.25E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00825 Beta-ketoacyl synthase 41 466 7.2E-217 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.40.366.10 748 869 4.4E-25 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1995 2010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.40.366.10 565 699 1.2E-43 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Gene3D G3DSA:3.90.180.10 1355 1665 3.3E-54 T 29-03-2018 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 SMART SM00823 Phosphopantetheine attachment site 1968 2040 2.3E-26 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11540 d88def4c486b927c9544f95a3e9a67f3 2126 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1380 1435 1.9E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 Gene3D G3DSA:1.10.1040.10 188 285 3.7E-32 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 1.1E-58 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 4.2E-33 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 SUPERFAMILY SSF48179 189 285 2.72E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 SUPERFAMILY SSF51735 4 186 8.4E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 PIRSF PIRSF000105 1 285 1.2E-79 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MSG_RS03370 c46099963fbb5e1193fa445c57e66f46 285 Gene3D G3DSA:3.40.50.720 1 187 3.1E-50 T 29-03-2018 MSG_RS06380 1e54553c2832853a901e1c81a15142ce 123 SUPERFAMILY SSF46785 7 117 2.35E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06380 1e54553c2832853a901e1c81a15142ce 123 Pfam PF12802 MarR family 14 70 6.4E-12 T 29-03-2018 MSG_RS06380 1e54553c2832853a901e1c81a15142ce 123 SMART SM00347 5 102 1.9E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS06380 1e54553c2832853a901e1c81a15142ce 123 Gene3D G3DSA:1.10.10.10 1 123 1.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 Pfam PF00067 Cytochrome P450 224 270 1.3E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 290 299 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 SUPERFAMILY SSF48264 25 326 1.83E-31 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 Gene3D G3DSA:1.10.630.10 140 322 3.8E-19 T 29-03-2018 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 PRINTS PR00359 B-class P450 signature 223 234 1.0E-7 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 PRINTS PR00359 B-class P450 signature 240 267 1.0E-7 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 PRINTS PR00359 B-class P450 signature 297 308 1.0E-7 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13710 8bcdabc5954d6368f23e6c224b97c6a3 362 PRINTS PR00359 B-class P450 signature 288 297 1.0E-7 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 SUPERFAMILY SSF52540 6 232 6.27E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Gene3D G3DSA:3.30.70.870 326 425 1.3E-23 T 29-03-2018 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Pfam PF00679 Elongation factor G C-terminus 421 505 1.2E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Gene3D G3DSA:3.30.70.240 426 504 8.2E-19 T 29-03-2018 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 SMART SM00838 420 508 0.0018 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Gene3D G3DSA:2.40.30.10 217 324 2.8E-24 T 29-03-2018 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.7E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.7E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.7E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 SUPERFAMILY SSF54980 423 537 4.8E-28 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Pfam PF03144 Elongation factor Tu domain 2 240 313 4.1E-11 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 SUPERFAMILY SSF50447 202 324 3.06E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 SUPERFAMILY SSF54980 326 412 5.47E-8 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 143 6.0E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 623 2.0E-271 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Gene3D G3DSA:2.40.50.250 507 597 1.2E-31 T 29-03-2018 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Gene3D G3DSA:3.40.50.300 2 216 2.5E-32 T 29-03-2018 MSG_RS19115 627e0bd65729c2a010ffcda3b5c49132 632 Pfam PF00009 Elongation factor Tu GTP binding domain 6 216 6.9E-50 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 SMART SM00304 170 222 5.4E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 SUPERFAMILY SSF47384 215 292 1.92E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 293 5.8E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 SMART SM00388 230 296 2.7E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Gene3D G3DSA:1.10.287.130 213 308 1.8E-9 T 29-03-2018 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 SUPERFAMILY SSF55874 303 443 4.19E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 SMART SM00387 338 446 7.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 444 2.7E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Gene3D G3DSA:3.30.565.10 309 446 2.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Gene3D G3DSA:1.20.5.1040 12 65 1.2E-4 T 29-03-2018 MSG_RS20660 d1fcc4ba5e6fdba7e5bab3d6924fe0ce 446 Pfam PF00672 HAMP domain 172 217 1.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 Gene3D G3DSA:3.40.50.300 285 486 6.6E-19 T 29-03-2018 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 390 404 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 352 367 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 404 423 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 458 475 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 475 494 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 437 449 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 312 326 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 545 557 9.7E-34 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 SMART SM00382 349 492 3.3E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 486 2.5E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 SUPERFAMILY SSF48452 34 58 4.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 SUPERFAMILY SSF48452 118 256 4.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 SUPERFAMILY SSF52540 314 572 2.72E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 Gene3D G3DSA:1.25.40.10 175 270 1.9E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 Gene3D G3DSA:1.25.40.10 4 174 1.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12705 35b9590acc63843ee5d9f47fc41cc1a1 610 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 42 592 1.3E-236 T 29-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA MSG_RS03115 6d7c3ba54733689324c35f98a77220c6 294 SUPERFAMILY SSF56219 24 288 9.42E-68 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS03115 6d7c3ba54733689324c35f98a77220c6 294 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 24 288 2.6E-78 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MSG_RS03115 6d7c3ba54733689324c35f98a77220c6 294 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 24 287 9.1E-57 T 29-03-2018 MSG_RS03115 6d7c3ba54733689324c35f98a77220c6 294 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 27 281 4.5E-18 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS03115 6d7c3ba54733689324c35f98a77220c6 294 Gene3D G3DSA:3.60.10.10 23 289 3.2E-43 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Gene3D G3DSA:3.30.300.30 364 470 1.2E-29 T 29-03-2018 MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Pfam PF00501 AMP-binding enzyme 8 370 1.9E-75 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 SUPERFAMILY SSF56801 7 465 3.79E-124 T 29-03-2018 MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Gene3D G3DSA:2.30.38.10 282 362 2.1E-21 T 29-03-2018 MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Gene3D G3DSA:3.40.50.980 133 281 8.0E-39 T 29-03-2018 MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 ProSitePatterns PS00455 Putative AMP-binding domain signature. 127 138 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Pfam PF13193 AMP-binding enzyme C-terminal domain 378 455 3.9E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS21530 e2ee649f88d9c91ee13828e4d247440d 471 Gene3D G3DSA:3.40.50.980 2 132 1.0E-27 T 29-03-2018 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 30 41 7.7E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 7.7E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 7.7E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 7.7E-27 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 Gene3D G3DSA:1.20.120.640 307 394 3.2E-12 T 29-03-2018 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 Pfam PF09190 DALR domain 342 394 2.9E-5 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 314 3.2E-127 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 SMART SM00840 342 403 1.6E-8 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 7 462 6.3E-132 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 SUPERFAMILY SSF47323 322 463 4.32E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 SUPERFAMILY SSF52374 7 314 6.7E-91 T 29-03-2018 MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 Gene3D G3DSA:3.40.50.620 1 306 3.5E-86 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS22720 7df6e6df8dfead169c463c5b5425aab0 469 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 7 464 34.77 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Pfam PF00970 Oxidoreductase FAD-binding domain 20 121 4.9E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 276 349 8.3E-14 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Gene3D G3DSA:3.40.50.80 113 240 2.6E-26 T 29-03-2018 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Gene3D G3DSA:2.40.30.10 11 112 6.8E-20 T 29-03-2018 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Gene3D G3DSA:3.10.20.30 241 360 2.2E-28 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 SUPERFAMILY SSF63380 14 121 1.7E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00410 Phenol hydroxylase reductase family signature 131 150 9.0E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 9.0E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 9.0E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00410 Phenol hydroxylase reductase family signature 116 125 9.0E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 155 164 4.1E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 4.1E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 131 150 4.1E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 72 79 4.1E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 SUPERFAMILY SSF52343 112 245 1.83E-32 T 29-03-2018 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 Pfam PF00175 Oxidoreductase NAD-binding domain 132 229 3.2E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 SUPERFAMILY SSF54292 238 356 7.47E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS22645 a8d9b0f350844893b7bbab2bc5070a31 360 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 307 315 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 Pfam PF00831 Ribosomal L29 protein 9 64 2.4E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 Gene3D G3DSA:1.10.287.310 6 68 1.1E-22 T 29-03-2018 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 16.536 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 2.5E-20 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 SUPERFAMILY SSF46561 8 67 4.32E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04500 2757a5156eac441c1278067b437c383e 81 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 SUPERFAMILY SSF75217 75 248 6.8E-43 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 Pfam PF04452 RNA methyltransferase 21 240 1.0E-60 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 PIRSF PIRSF015601 3 247 8.7E-45 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 22 243 5.4E-33 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 Gene3D G3DSA:2.40.240.20 1 71 1.5E-18 T 29-03-2018 MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 SUPERFAMILY SSF88697 5 70 1.14E-11 T 29-03-2018 IPR015947 PUA-like domain MSG_RS16720 319422f24c14efcdda9f0cafca7e5d17 268 Gene3D G3DSA:3.40.1280.10 73 255 7.4E-50 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 19 135 6.4E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 SUPERFAMILY SSF53137 23 138 7.85E-50 T 29-03-2018 MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 138 34.297 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 Pfam PF00411 Ribosomal protein S11 28 137 1.1E-48 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 PIRSF PIRSF002131 6 138 4.0E-55 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 ProSitePatterns PS00054 Ribosomal protein S11 signature. 106 128 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site MSG_RS04835 5e8b01e0272245587bca551380a52c61 138 Gene3D G3DSA:3.30.420.80 12 138 2.7E-46 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MSG_RS08255 ae3e90ee8bf36a92b602f36d1a2222b2 131 SUPERFAMILY SSF52980 22 115 5.09E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MSG_RS08255 ae3e90ee8bf36a92b602f36d1a2222b2 131 Hamap MF_00048 UPF0102 protein YraN [yraN]. 15 127 21.984 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MSG_RS08255 ae3e90ee8bf36a92b602f36d1a2222b2 131 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 16 114 4.3E-20 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MSG_RS08255 ae3e90ee8bf36a92b602f36d1a2222b2 131 Pfam PF02021 Uncharacterised protein family UPF0102 22 114 8.8E-26 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MSG_RS08255 ae3e90ee8bf36a92b602f36d1a2222b2 131 Gene3D G3DSA:3.40.1350.10 21 130 1.1E-30 T 29-03-2018 MSG_RS00415 3723d5399ec8941b884763e60f52a2ab 98 SUPERFAMILY SSF47413 29 96 2.17E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS00415 3723d5399ec8941b884763e60f52a2ab 98 Pfam PF01381 Helix-turn-helix 42 91 3.8E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS00415 3723d5399ec8941b884763e60f52a2ab 98 Gene3D G3DSA:1.10.260.40 55 97 1.7E-15 T 29-03-2018 MSG_RS00415 3723d5399ec8941b884763e60f52a2ab 98 Gene3D G3DSA:1.10.10.10 1 54 2.2E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00415 3723d5399ec8941b884763e60f52a2ab 98 SMART SM00530 39 94 3.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 Pfam PF00551 Formyl transferase 14 191 8.8E-43 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 Gene3D G3DSA:3.40.50.170 1 208 1.3E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 197 1.4E-64 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 SUPERFAMILY SSF53328 14 207 1.26E-53 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 143 166 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS20320 f931c52f9b747852286f42cd9c78a929 209 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 14 197 26.433 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MSG_RS03550 1865a3675ae2b9341583c0665fb85a97 171 SUPERFAMILY SSF54637 11 151 5.39E-35 T 29-03-2018 IPR029069 HotDog domain MSG_RS03550 1865a3675ae2b9341583c0665fb85a97 171 Hamap MF_00799 UPF0336 protein . 1 152 33.808 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS03550 1865a3675ae2b9341583c0665fb85a97 171 Gene3D G3DSA:3.10.129.10 16 167 5.5E-31 T 29-03-2018 MSG_RS03550 1865a3675ae2b9341583c0665fb85a97 171 PIRSF PIRSF018072 3 154 5.5E-57 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS03550 1865a3675ae2b9341583c0665fb85a97 171 Pfam PF13452 N-terminal half of MaoC dehydratase 10 141 1.5E-31 T 29-03-2018 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 276 285 2.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 251 270 2.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 174 184 2.0E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 SUPERFAMILY SSF46458 11 138 2.47E-21 T 29-03-2018 IPR009050 Globin-like MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Gene3D G3DSA:2.40.30.10 137 239 3.8E-18 T 29-03-2018 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 SUPERFAMILY SSF52343 244 385 2.88E-24 T 29-03-2018 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00410 Phenol hydroxylase reductase family signature 251 270 9.3E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00410 Phenol hydroxylase reductase family signature 276 285 9.3E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 PRINTS PR00410 Phenol hydroxylase reductase family signature 174 186 9.3E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Pfam PF00175 Oxidoreductase NAD-binding domain 252 368 4.6E-7 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Pfam PF00042 Globin 22 103 7.7E-6 T 29-03-2018 IPR000971 Globin GO:0020037 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 SUPERFAMILY SSF63380 146 241 9.68E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Gene3D G3DSA:3.40.50.80 240 386 3.8E-17 T 29-03-2018 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Pfam PF00970 Oxidoreductase FAD-binding domain 150 241 1.3E-16 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MSG_RS02775 105b8115e88d94ba7f075c10c69ee806 389 Gene3D G3DSA:1.10.490.10 1 136 4.5E-26 T 29-03-2018 MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 Gene3D G3DSA:1.10.10.60 27 208 8.0E-11 T 29-03-2018 MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 SMART SM00342 170 252 6.1E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 Pfam PF12833 Helix-turn-helix domain 176 252 4.9E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 SUPERFAMILY SSF51182 12 210 9.78E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 SUPERFAMILY SSF46689 210 253 8.96E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS13085 dc828119c9a3bf991b680fd2e1cc79c5 257 Gene3D G3DSA:1.10.10.60 209 255 5.3E-5 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 SUPERFAMILY SSF52777 93 338 1.16E-51 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Gene3D G3DSA:1.10.287.1150 365 450 6.9E-23 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Gene3D G3DSA:3.40.50.970 878 1094 6.4E-50 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Pfam PF00676 Dehydrogenase E1 component 492 819 2.9E-55 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1086 1232 4.1E-41 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 SUPERFAMILY SSF52518 869 1087 4.12E-43 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 SUPERFAMILY SSF52518 405 818 4.78E-82 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Gene3D G3DSA:3.30.559.10 88 341 1.7E-48 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 108 338 3.7E-53 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 SMART SM00861 882 1081 1.5E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Gene3D G3DSA:3.40.50.970 451 817 1.2E-90 T 29-03-2018 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 361 1231 2.2E-298 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 5 37 9.1E-11 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 Pfam PF02779 Transketolase, pyrimidine binding domain 881 1081 3.8E-52 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS18705 141cab745b8f76cc9df16f26f94f0747 1233 PIRSF PIRSF000157 1 1233 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 532 3.7E-33 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 326 1.0E-18 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 SUPERFAMILY SSF52518 11 179 5.4E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Gene3D G3DSA:3.40.50.970 5 192 2.5E-41 T 29-03-2018 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 177 2.0E-43 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 SUPERFAMILY SSF52518 361 541 5.68E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Gene3D G3DSA:3.40.50.970 336 547 4.0E-41 T 29-03-2018 MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 Gene3D G3DSA:3.40.50.1220 193 335 2.3E-21 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS12790 940c1c331d008f0be13c7b614e560442 547 SUPERFAMILY SSF52467 164 346 3.05E-27 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 225 313 2.2E-10 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Gene3D G3DSA:1.10.540.10 89 218 9.5E-24 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 437 456 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 337 465 3.5E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 SUPERFAMILY SSF47203 338 466 1.29E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 SUPERFAMILY SSF56645 102 325 4.32E-44 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Gene3D G3DSA:2.40.110.10 224 324 1.5E-17 T 29-03-2018 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 108 217 2.3E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06840 1cc10a734e679642a2721935b4700633 469 Gene3D G3DSA:1.20.140.10 325 468 8.6E-33 T 29-03-2018 MSG_RS21050 1d6e4ab46129870d035961429e84f665 195 Gene3D G3DSA:1.20.120.80 12 195 4.1E-41 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS21050 1d6e4ab46129870d035961429e84f665 195 Pfam PF03896 Translocon-associated protein (TRAP), alpha subunit 112 185 7.3E-6 T 29-03-2018 IPR005595 Translocon-associated protein (TRAP), alpha subunit GO:0005789 Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS21050 1d6e4ab46129870d035961429e84f665 195 SUPERFAMILY SSF81452 17 194 7.85E-40 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS21050 1d6e4ab46129870d035961429e84f665 195 Pfam PF00510 Cytochrome c oxidase subunit III 20 193 1.4E-14 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS24235 c9883a4b9452a87d3895b6688dcd24ed 250 Pfam PF01553 Acyltransferase 23 149 3.8E-32 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS24235 c9883a4b9452a87d3895b6688dcd24ed 250 SUPERFAMILY SSF69593 14 188 6.8E-32 T 29-03-2018 MSG_RS24235 c9883a4b9452a87d3895b6688dcd24ed 250 SMART SM00563 38 152 1.9E-35 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS24235 c9883a4b9452a87d3895b6688dcd24ed 250 Gene3D G3DSA:3.40.1130.10 5 210 2.6E-44 T 29-03-2018 MSG_RS08145 5b6754ad96d562aaceb3b50cb2e0d07f 268 Pfam PF12697 Alpha/beta hydrolase family 18 242 1.7E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS08145 5b6754ad96d562aaceb3b50cb2e0d07f 268 SUPERFAMILY SSF53474 190 257 9.28E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08145 5b6754ad96d562aaceb3b50cb2e0d07f 268 SUPERFAMILY SSF53474 12 118 9.28E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08145 5b6754ad96d562aaceb3b50cb2e0d07f 268 Gene3D G3DSA:3.40.50.1820 14 261 5.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 86 983 16.664 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 91 315 6.3E-33 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 589 827 2.3E-66 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:1.20.120.330 327 487 1.6E-43 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:1.20.120.330 837 994 2.1E-43 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 SUPERFAMILY SSF81593 842 993 3.69E-36 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:1.10.4050.10 563 673 4.0E-16 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:1.10.4050.10 62 169 1.1E-14 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Pfam PF08335 GlnD PII-uridylyltransferase 850 992 2.5E-20 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Pfam PF08335 GlnD PII-uridylyltransferase 336 483 6.5E-35 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 SUPERFAMILY SSF81301 561 835 3.92E-64 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 SUPERFAMILY SSF81301 73 323 9.48E-54 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:3.30.460.10 176 323 4.0E-47 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 Gene3D G3DSA:3.30.460.10 674 835 1.5E-50 T 29-03-2018 MSG_RS15495 289067a5c8fe5601e202307e7b935c04 994 SUPERFAMILY SSF81593 329 483 3.92E-34 T 29-03-2018 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 Gene3D G3DSA:3.40.50.1820 1 260 1.5E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00412 Epoxide hydrolase signature 40 55 2.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00412 Epoxide hydrolase signature 234 256 2.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00412 Epoxide hydrolase signature 97 110 2.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00412 Epoxide hydrolase signature 83 96 2.4E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 2.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 2.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 2.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 2.0E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 Pfam PF12697 Alpha/beta hydrolase family 15 251 5.1E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS03840 0cc7dad1447fea1d276b9074f83e9be9 260 SUPERFAMILY SSF53474 3 258 1.8E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02710 dd2fd5efee9e9b9a885297bb56e2ea4c 316 Gene3D G3DSA:3.20.20.140 16 315 9.2E-58 T 29-03-2018 MSG_RS02710 dd2fd5efee9e9b9a885297bb56e2ea4c 316 Pfam PF04909 Amidohydrolase 33 315 3.7E-45 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS02710 dd2fd5efee9e9b9a885297bb56e2ea4c 316 SUPERFAMILY SSF51556 13 316 1.04E-75 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 PIRSF PIRSF005739 17 360 1.2E-52 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 Gene3D G3DSA:1.10.10.10 27 118 2.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 Pfam PF16864 Dimerisation domain 36 111 3.2E-10 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 Pfam PF00891 O-methyltransferase 129 344 8.3E-50 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 Gene3D G3DSA:3.40.50.150 119 361 1.8E-46 T 29-03-2018 MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 SUPERFAMILY SSF46785 31 114 5.66E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07120 ce0c0b3812dc7af27aef60da9c9995cb 361 SUPERFAMILY SSF53335 117 358 1.21E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03740 b1d810f39b4479067a31f55846435975 339 SUPERFAMILY SSF51735 1 118 1.53E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03740 b1d810f39b4479067a31f55846435975 339 SUPERFAMILY SSF51735 155 333 1.53E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03740 b1d810f39b4479067a31f55846435975 339 Gene3D G3DSA:3.90.25.10 214 335 8.9E-26 T 29-03-2018 MSG_RS03740 b1d810f39b4479067a31f55846435975 339 Gene3D G3DSA:3.40.50.720 1 213 5.3E-25 T 29-03-2018 MSG_RS03740 b1d810f39b4479067a31f55846435975 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 259 1.7E-36 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS08560 399965e9ef2c823d12638ba5f41055ad 249 SUPERFAMILY SSF52096 1 235 9.56E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS08560 399965e9ef2c823d12638ba5f41055ad 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 226 2.4E-51 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS08560 399965e9ef2c823d12638ba5f41055ad 249 Gene3D G3DSA:3.90.226.10 1 230 3.7E-65 T 29-03-2018 MSG_RS15380 59c8c9e0dcf5d4bc758778bc3cc67bb3 250 Pfam PF02654 Cobalamin-5-phosphate synthase 8 241 1.0E-45 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15380 59c8c9e0dcf5d4bc758778bc3cc67bb3 250 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 250 42.882 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF47336 934 1002 4.46E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SMART SM00823 Phosphopantetheine attachment site 938 1006 3.8E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 ProSitePatterns PS00012 Phosphopantetheine attachment site. 962 977 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SMART SM00825 Beta-ketoacyl synthase 19 452 1.7E-178 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 403 514 1.8E-17 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.40.366.10 549 690 1.0E-42 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF00668 Condensation domain 1031 1454 3.0E-32 T 29-03-2018 IPR001242 Condensation domain MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:1.10.1200.10 935 1010 3.5E-19 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.40.47.10 286 450 1.3E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF00550 Phosphopantetheine attachment site 940 1002 9.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 845 4.6E-95 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF53901 427 448 1.48E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF53901 15 134 1.48E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF53901 169 393 1.48E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF52777 1210 1455 1.56E-29 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF52151 549 684 2.88E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF52151 744 835 2.88E-65 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF52777 1029 1194 4.34E-18 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 17 273 1.3E-68 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.30.559.10 1014 1206 8.7E-14 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 186 202 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.40.47.10 10 285 1.4E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SMART SM01294 939 1002 0.005 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 SUPERFAMILY SSF55048 682 741 5.62E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.40.366.10 735 843 1.8E-23 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF00698 Acyl transferase domain 551 828 2.8E-53 T 29-03-2018 IPR014043 Acyl transferase MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Gene3D G3DSA:3.30.70.250 691 734 8.3E-17 T 29-03-2018 MSG_RS08040 36919cb243d2bbe8267e9550cb04cb80 1478 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 281 400 1.7E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Pfam PF05000 RNA polymerase Rpb1, domain 4 772 828 7.5E-8 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1268 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 560 1.6E-35 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 SMART SM00663 310 589 5.8E-173 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 SUPERFAMILY SSF64484 5 1269 0.0 T 29-03-2018 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Gene3D G3DSA:2.40.40.20 421 563 5.8E-40 T 29-03-2018 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Gene3D G3DSA:2.40.50.100 987 1116 2.6E-33 T 29-03-2018 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 736 3.9E-27 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1278 17.378 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 8.7E-82 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04210 74435b00a8ff11644e3b950c2d6d2f6e 1316 Pfam PF04998 RNA polymerase Rpb1, domain 5 843 1216 5.9E-64 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS11960 c682a030f991f8b2d0361387175ff84b 108 Pfam PF13466 STAS domain 19 75 2.2E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS11960 c682a030f991f8b2d0361387175ff84b 108 SUPERFAMILY SSF52091 10 98 8.83E-14 T 29-03-2018 IPR002645 STAS domain MSG_RS11960 c682a030f991f8b2d0361387175ff84b 108 Gene3D G3DSA:3.30.750.24 5 85 3.2E-9 T 29-03-2018 IPR002645 STAS domain MSG_RS09165 0a599d3a185001212bc28a7c48bfa345 231 Pfam PF06778 Chlorite dismutase 32 221 9.5E-74 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase MSG_RS09165 0a599d3a185001212bc28a7c48bfa345 231 Gene3D G3DSA:3.30.70.1030 7 126 4.3E-38 T 29-03-2018 MSG_RS09165 0a599d3a185001212bc28a7c48bfa345 231 Gene3D G3DSA:3.30.70.1100 128 228 3.3E-32 T 29-03-2018 MSG_RS09165 0a599d3a185001212bc28a7c48bfa345 231 SUPERFAMILY SSF54909 4 230 2.6E-76 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 SUPERFAMILY SSF56801 5 513 3.92E-146 T 29-03-2018 MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Gene3D G3DSA:3.40.50.980 3 181 7.6E-40 T 29-03-2018 MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Pfam PF00501 AMP-binding enzyme 16 419 2.3E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Gene3D G3DSA:2.30.38.10 335 413 4.1E-22 T 29-03-2018 MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 504 3.3E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Gene3D G3DSA:3.40.50.980 182 334 2.1E-44 T 29-03-2018 MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS22580 3e77bc9b6ed9654ff5aa92e9e3cd3561 514 Gene3D G3DSA:3.30.300.30 415 514 1.5E-26 T 29-03-2018 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 194 217 1.2E-25 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 119 138 1.2E-25 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 91 117 1.2E-25 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 PRINTS PR00447 Natural resistance-associated macrophage protein signature 350 369 1.2E-25 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 Pfam PF01566 Natural resistance-associated macrophage protein 32 380 1.3E-111 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 13 374 2.1E-88 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS20500 58072e7054237e631631da394c2bffd0 409 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 3 406 34.177 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 ProSitePatterns PS00321 recA signature. 215 223 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 SUPERFAMILY SSF54752 270 328 8.24E-20 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 Gene3D G3DSA:3.30.250.10 271 328 9.6E-25 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 SUPERFAMILY SSF52540 6 269 1.07E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 Hamap MF_00268 Protein RecA [recA]. 7 331 52.746 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 5.9E-174 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 Pfam PF00154 recA bacterial DNA recombination protein 9 270 3.5E-143 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 Gene3D G3DSA:3.40.50.300 28 270 3.8E-49 T 29-03-2018 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 245 274 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 299 316 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 95 124 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 212 240 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 167 196 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 PRINTS PR00142 RecA protein signature 129 158 1.8E-83 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MSG_RS08885 29bbbab66e767222eb688c2e7becdc43 350 SMART SM00382 59 230 3.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 PIRSF PIRSF001455 8 345 1.3E-96 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 Pfam PF01761 3-dehydroquinate synthase 69 325 3.3E-93 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 Gene3D G3DSA:1.20.1090.10 175 358 4.1E-57 T 29-03-2018 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 Gene3D G3DSA:3.40.50.1970 7 174 6.5E-42 T 29-03-2018 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 SUPERFAMILY SSF56796 14 356 2.36E-102 T 29-03-2018 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 18 340 6.6E-104 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MSG_RS09920 2afa83a22df6680b83532f3ea95a5b4a 361 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 358 37.371 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MSG_RS21545 3e9c61eacf440a0a3d1f0274ba3ca502 345 Gene3D G3DSA:3.40.50.10540 4 345 2.6E-91 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21545 3e9c61eacf440a0a3d1f0274ba3ca502 345 SUPERFAMILY SSF89796 6 341 3.14E-93 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21545 3e9c61eacf440a0a3d1f0274ba3ca502 345 Pfam PF02515 CoA-transferase family III 9 315 2.7E-81 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS20060 74fe758fc77bb2925b5de7c15d2dae79 506 SUPERFAMILY SSF51445 67 265 1.14E-8 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS20060 74fe758fc77bb2925b5de7c15d2dae79 506 Gene3D G3DSA:3.20.20.80 65 363 3.6E-10 T 29-03-2018 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 29 266 5.4E-84 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 PIRSF PIRSF000477 2 268 8.6E-102 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 Pfam PF01048 Phosphorylase superfamily 29 266 2.8E-41 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 Gene3D G3DSA:3.40.50.1580 1 268 4.7E-62 T 29-03-2018 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 SUPERFAMILY SSF53167 12 267 5.98E-78 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 29 266 6.2E-107 T 29-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MSG_RS05560 5eae9f581a24e88b5daced18e208c171 268 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 83 124 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 57 70 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 336 428 1.4E-27 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 TIGRFAM TIGR02079 THD1: threonine dehydratase 21 429 4.1E-191 T 29-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 SUPERFAMILY SSF53686 20 373 3.93E-91 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 Gene3D G3DSA:3.40.1020.10 240 429 7.1E-31 T 29-03-2018 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 Gene3D G3DSA:3.40.50.1100 177 239 4.1E-9 T 29-03-2018 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 Gene3D G3DSA:3.40.50.1100 26 176 6.9E-35 T 29-03-2018 MSG_RS11015 c8b748be880bc31d3490311622e87ab1 430 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 323 6.1E-75 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 SUPERFAMILY SSF51230 1 96 7.72E-28 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 SUPERFAMILY SSF47005 270 314 1.26E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 352 580 3.4E-71 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 SUPERFAMILY SSF52777 339 580 3.78E-74 T 29-03-2018 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 588 1.1E-287 T 29-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Gene3D G3DSA:3.30.559.10 329 582 2.3E-75 T 29-03-2018 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 160 189 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Gene3D G3DSA:4.10.320.10 272 323 7.5E-21 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 SUPERFAMILY SSF51230 135 228 2.62E-26 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Pfam PF02817 e3 binding domain 277 311 5.6E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Pfam PF00364 Biotin-requiring enzyme 138 209 2.0E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Pfam PF00364 Biotin-requiring enzyme 5 75 3.2E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Gene3D G3DSA:3.90.1170.30 2 45 1.0E-18 T 29-03-2018 MSG_RS15420 87172fb755a142a5fd78ba806ebc2b49 588 Gene3D G3DSA:3.90.1170.30 46 180 2.3E-34 T 29-03-2018 MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 Pfam PF01106 NifU-like domain 93 162 4.1E-19 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 97 156 9.0E-8 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 SUPERFAMILY SSF50022 193 285 1.79E-9 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 Gene3D G3DSA:3.30.300.130 87 169 5.0E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 Gene3D G3DSA:2.102.10.10 194 298 1.3E-10 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS14015 38e61958fa99795e41fe725604e2f4ee 299 SUPERFAMILY SSF117916 84 164 7.41E-18 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Gene3D G3DSA:3.40.50.740 62 144 2.5E-9 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Gene3D G3DSA:3.40.50.740 362 421 2.1E-12 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 SUPERFAMILY SSF50692 607 739 4.29E-23 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Pfam PF01568 Molydopterin dinucleotide binding domain 621 733 7.5E-15 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Gene3D G3DSA:2.40.40.20 565 748 2.3E-19 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 56 5.3E-12 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Pfam PF00384 Molybdopterin oxidoreductase 60 429 2.1E-30 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 SUPERFAMILY SSF53706 4 477 9.29E-113 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Gene3D G3DSA:2.20.25.90 2 61 1.4E-12 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 Gene3D G3DSA:3.40.228.10 145 361 1.6E-40 T 29-03-2018 MSG_RS01880 e6948c0366e32bb2c479d69ed605d9b5 749 SMART SM00926 3 57 7.5E-14 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 Gene3D G3DSA:3.40.50.720 6 259 1.8E-61 T 29-03-2018 MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 202 4.2E-5 T 29-03-2018 MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 SUPERFAMILY SSF51735 5 259 4.51E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 3.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 3.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS22525 5e5a2b51aa7b19252661a8d46546df61 301 Pfam PF00106 short chain dehydrogenase 7 211 1.1E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13140 a59841e6c2d90be507817b3e48e6e3fe 252 SUPERFAMILY SSF52096 3 251 5.49E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS13140 a59841e6c2d90be507817b3e48e6e3fe 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 6.3E-44 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS13140 a59841e6c2d90be507817b3e48e6e3fe 252 Gene3D G3DSA:3.90.226.10 1 207 2.3E-56 T 29-03-2018 MSG_RS13140 a59841e6c2d90be507817b3e48e6e3fe 252 Gene3D G3DSA:1.10.12.10 208 249 1.3E-4 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Gene3D G3DSA:1.10.357.10 70 191 1.0E-10 T 29-03-2018 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 SUPERFAMILY SSF48498 105 195 4.79E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Gene3D G3DSA:1.10.10.60 49 69 1.8E-9 T 29-03-2018 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Gene3D G3DSA:1.10.10.60 3 48 1.2E-10 T 29-03-2018 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Gene3D G3DSA:3.10.129.10 192 336 2.3E-22 T 29-03-2018 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 SUPERFAMILY SSF54637 224 328 5.2E-23 T 29-03-2018 IPR029069 HotDog domain MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 SUPERFAMILY SSF46689 12 83 1.95E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 223 326 1.4E-16 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MSG_RS17765 52a2e5471b9fab7bb8de583338988cd5 341 Pfam PF03061 Thioesterase superfamily 245 319 1.9E-10 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS05330 3e7ad8905fcdb54ff3a093118af75d13 463 SUPERFAMILY SSF140459 2 174 2.04E-63 T 29-03-2018 MSG_RS05330 3e7ad8905fcdb54ff3a093118af75d13 463 Gene3D G3DSA:1.10.287.1060 22 105 3.6E-8 T 29-03-2018 MSG_RS05330 3e7ad8905fcdb54ff3a093118af75d13 463 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 395 3.2E-8 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS05330 3e7ad8905fcdb54ff3a093118af75d13 463 Pfam PF00823 PPE family 6 161 3.5E-62 T 29-03-2018 IPR000030 PPE family MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF51735 1533 1699 3.28E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF51735 1189 1400 2.1E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF14765 Polyketide synthase dehydratase 896 1179 1.3E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.50.720 1759 1985 1.0E-37 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF55048 658 724 2.49E-6 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1444 1510 1.8E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF08659 KR domain 1763 1945 1.4E-53 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.90.180.10 1663 1742 0.27 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00829 1427 1739 5.0E-159 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.50.720 1554 1662 3.2E-26 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.47.10 271 429 3.8E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.10.129.10 898 1016 1.1E-7 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF50129 1422 1557 3.62E-35 T 29-03-2018 IPR011032 GroES-like MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.366.10 531 670 3.6E-39 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00826 896 1057 2.4E-34 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 471 1.2E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF53901 7 376 5.01E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.47.10 2 268 2.1E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:1.10.1200.10 2019 2109 7.0E-12 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 538 833 1.6E-90 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.30.70.250 671 713 3.5E-8 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00823 Phosphopantetheine attachment site 2036 2101 3.6E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF51735 1759 2001 9.74E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00825 Beta-ketoacyl synthase 9 431 2.1E-186 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 377 2.1E-37 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF00698 Acyl transferase domain 536 852 2.1E-94 T 29-03-2018 IPR014043 Acyl transferase MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 256 8.2E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.90.180.10 1414 1553 1.0E-37 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1763 1946 2.0E-37 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF00107 Zinc-binding dehydrogenase 1568 1658 3.9E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Gene3D G3DSA:3.40.366.10 714 834 3.6E-23 T 29-03-2018 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF47336 2029 2107 1.83E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF52151 536 660 1.2E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 SUPERFAMILY SSF52151 725 821 1.2E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS19060 0d83772af3f6909af1bd3020fc15ad8e 2111 Pfam PF00550 Phosphopantetheine attachment site 2035 2097 1.0E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 105 4.7E-37 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 Pfam PF00467 KOW motif 5 35 1.4E-10 T 29-03-2018 IPR005824 KOW MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 Gene3D G3DSA:2.30.30.30 1 93 6.4E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 SUPERFAMILY SSF50104 1 102 8.28E-30 T 29-03-2018 IPR008991 Translation protein SH3-like domain MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 99 20.076 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 SMART SM00739 2 29 3.9E-6 T 29-03-2018 IPR005824 KOW MSG_RS04560 4213b965dd3c5a26a080980fed857f6c 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 105 7.0E-24 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04780 51e3867fdbbd5fcbd939c6bf247f7bfc 368 Pfam PF01757 Acyltransferase family 13 325 8.3E-18 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS02810 a0e02d91428a84f4a95181d011353c7a 259 PIRSF PIRSF018982 1 242 1.8E-81 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MSG_RS02810 a0e02d91428a84f4a95181d011353c7a 259 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 3 233 3.6E-82 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MSG_RS08325 ae479357203f9092f5f2a9f83cac8f0b 139 SMART SM00347 26 126 2.8E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS08325 ae479357203f9092f5f2a9f83cac8f0b 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MSG_RS08325 ae479357203f9092f5f2a9f83cac8f0b 139 Pfam PF01047 MarR family 33 90 1.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS08325 ae479357203f9092f5f2a9f83cac8f0b 139 SUPERFAMILY SSF46785 6 136 1.83E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08325 ae479357203f9092f5f2a9f83cac8f0b 139 Gene3D G3DSA:1.10.10.10 2 139 3.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09040 b5806bed6a11550d88b693d685e379dd 269 Gene3D G3DSA:3.30.420.40 141 266 5.3E-26 T 29-03-2018 MSG_RS09040 b5806bed6a11550d88b693d685e379dd 269 Gene3D G3DSA:3.30.420.40 4 140 5.0E-22 T 29-03-2018 MSG_RS09040 b5806bed6a11550d88b693d685e379dd 269 Pfam PF00480 ROK family 26 180 4.9E-15 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MSG_RS09040 b5806bed6a11550d88b693d685e379dd 269 SUPERFAMILY SSF53067 25 262 9.13E-32 T 29-03-2018 MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 Gene3D G3DSA:3.40.50.720 2 256 5.2E-36 T 29-03-2018 MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 SUPERFAMILY SSF51735 3 255 1.53E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 145 251 7.3E-17 T 29-03-2018 MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14115 ff4646b01c0c8f31cc9a84c80fce4c13 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01805 27d951ef48f98ad22dfccb368e619659 316 Pfam PF00892 EamA-like transporter family 6 131 2.8E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MSG_RS01805 27d951ef48f98ad22dfccb368e619659 316 Pfam PF00892 EamA-like transporter family 148 279 4.2E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MSG_RS01805 27d951ef48f98ad22dfccb368e619659 316 SUPERFAMILY SSF103481 189 282 2.88E-6 T 29-03-2018 MSG_RS01805 27d951ef48f98ad22dfccb368e619659 316 SUPERFAMILY SSF103481 36 136 1.44E-12 T 29-03-2018 MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 Gene3D G3DSA:3.90.1310.10 240 317 0.0022 T 29-03-2018 MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 35 142 1.1E-22 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 Pfam PF00905 Penicillin binding protein transpeptidase domain 332 590 2.4E-37 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 Gene3D G3DSA:3.10.450.100 33 137 1.1E-10 T 29-03-2018 MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 SUPERFAMILY SSF56601 312 605 2.63E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08415 10f0c0e934940459ee34b90956d047a8 612 Gene3D G3DSA:3.40.710.10 318 606 1.4E-53 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF50129 1354 1483 3.8E-23 T 29-03-2018 IPR011032 GroES-like MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.90.180.10 1336 1642 2.5E-53 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF51735 1670 1875 7.52E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00825 Beta-ketoacyl synthase 36 459 1.3E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.40.366.10 736 858 1.8E-30 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.40.366.10 557 694 1.4E-47 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:1.10.1200.10 1951 2061 4.6E-21 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 523 5.6E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF53901 33 405 2.28E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 281 2.1E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF51735 1449 1594 3.54E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF08990 Erythronolide synthase docking 2 27 3.9E-8 T 29-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 561 852 8.9E-113 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1371 1426 1.9E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF47336 1950 2035 9.42E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF51735 1130 1330 1.18E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 406 2.8E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.10.129.10 918 1045 8.7E-7 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF00550 Phosphopantetheine attachment site 1961 2025 1.9E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM01294 1959 2025 3.0E-5 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00823 Phosphopantetheine attachment site 1958 2029 9.0E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.30.70.250 695 735 8.6E-17 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF00698 Acyl transferase domain 559 871 3.3E-64 T 29-03-2018 IPR014043 Acyl transferase MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF08659 KR domain 1674 1852 5.4E-62 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00826 918 1079 8.2E-74 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.40.50.720 1643 1941 2.7E-51 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF13602 Zinc-binding dehydrogenase 1525 1653 8.0E-19 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF55048 684 745 4.97E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00829 1354 1653 9.9E-166 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Pfam PF14765 Polyketide synthase dehydratase 918 1187 5.4E-55 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.40.47.10 26 293 5.4E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1674 1854 2.7E-65 T 29-03-2018 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1984 1999 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 Gene3D G3DSA:3.40.47.10 296 457 4.3E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF52151 746 846 1.05E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11545 b37c492f10936f2ba322ecf316175c10 2120 SUPERFAMILY SSF52151 557 685 1.05E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.1E-65 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 SUPERFAMILY SSF55194 3 184 2.09E-67 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.336 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 Gene3D G3DSA:1.10.132.20 2 73 4.9E-8 T 29-03-2018 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 Gene3D G3DSA:1.10.132.20 74 184 1.9E-36 T 29-03-2018 MSG_RS08360 33fc7ce72d84841f2653d1c2338d4066 185 Pfam PF01765 Ribosome recycling factor 21 183 1.6E-60 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 ProSitePatterns PS00433 Phosphofructokinase signature. 267 285 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 Gene3D G3DSA:3.40.50.450 238 333 1.4E-10 T 29-03-2018 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PIRSF PIRSF000532 1 341 1.6E-112 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 Pfam PF00365 Phosphofructokinase 2 298 1.8E-102 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 343 43.733 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 263 285 7.9E-76 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 2.0E-139 T 29-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 SUPERFAMILY SSF53784 1 333 6.02E-119 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MSG_RS07730 5585c9d4f64f5f7cfea9450dcf04dff6 343 Gene3D G3DSA:3.40.50.450 1 233 1.2E-77 T 29-03-2018 MSG_RS15995 339862bd91ad0fd78a6c5d8c7a1739f7 369 Pfam PF13439 Glycosyltransferase Family 4 15 179 4.5E-10 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS15995 339862bd91ad0fd78a6c5d8c7a1739f7 369 Pfam PF00534 Glycosyl transferases group 1 199 343 7.5E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS15995 339862bd91ad0fd78a6c5d8c7a1739f7 369 Gene3D G3DSA:3.40.50.2000 190 352 4.8E-34 T 29-03-2018 MSG_RS15995 339862bd91ad0fd78a6c5d8c7a1739f7 369 SUPERFAMILY SSF53756 1 363 4.54E-61 T 29-03-2018 MSG_RS15995 339862bd91ad0fd78a6c5d8c7a1739f7 369 Gene3D G3DSA:3.40.50.2000 1 189 8.8E-8 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Gene3D G3DSA:2.40.30.10 215 307 1.8E-19 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 PRINTS PR00315 GTP-binding elongation factor signature 138 147 6.7E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.7E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 PRINTS PR00315 GTP-binding elongation factor signature 6 19 6.7E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.7E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.7E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 414 3.2E-173 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 SUPERFAMILY SSF50447 220 308 1.16E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 439 610 1.0E-62 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 1 443 48.101 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Pfam PF01583 Adenylylsulphate kinase 442 593 4.7E-67 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 SUPERFAMILY SSF50465 311 415 1.01E-30 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 441 614 36.411 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 SUPERFAMILY SSF52540 4 204 1.45E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Gene3D G3DSA:2.40.30.10 309 416 1.3E-26 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Gene3D G3DSA:3.40.50.300 2 212 8.0E-38 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Pfam PF00009 Elongation factor Tu GTP binding domain 5 188 1.4E-39 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 Gene3D G3DSA:3.40.50.300 438 613 1.4E-39 T 29-03-2018 MSG_RS18445 b2fb336572ba1d6bd8938e6c250501dd 614 SUPERFAMILY SSF52540 441 611 1.12E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 56 75 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 45 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 56 1.1E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 ProSitePatterns PS00519 AsnC-type HTH domain signature. 47 73 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 Pfam PF13404 AsnC-type helix-turn-helix domain 29 69 4.3E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 Gene3D G3DSA:3.30.70.920 81 171 2.2E-20 T 29-03-2018 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 SMART SM00344 29 133 1.1E-34 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 Gene3D G3DSA:1.10.10.10 26 80 2.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 Pfam PF01037 Lrp/AsnC ligand binding domain 94 163 1.7E-16 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 SUPERFAMILY SSF46785 28 87 1.71E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04230 a4d32a4a0fbb44056605ca5ab17d0c23 174 SUPERFAMILY SSF54909 91 169 1.13E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS14570 35a422549af3a8f859f6e2f3d457697f 232 Pfam PF01738 Dienelactone hydrolase family 13 228 1.5E-57 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MSG_RS14570 35a422549af3a8f859f6e2f3d457697f 232 Gene3D G3DSA:3.40.50.1820 1 232 2.0E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14570 35a422549af3a8f859f6e2f3d457697f 232 SUPERFAMILY SSF53474 2 229 1.99E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 Gene3D G3DSA:3.30.70.20 45 100 4.0E-9 T 29-03-2018 MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 SUPERFAMILY SSF54862 4 82 5.82E-20 T 29-03-2018 MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 Pfam PF00037 4Fe-4S binding domain 35 56 1.8E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 Gene3D G3DSA:3.30.70.20 2 44 8.8E-11 T 29-03-2018 MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS19080 2c624c7f69d75f565c7108da6f622e1b 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.0E-18 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 SUPERFAMILY SSF46894 732 794 5.44E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 770 782 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 754 770 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 740 754 2.5E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 Pfam PF00196 Bacterial regulatory proteins, luxR family 739 793 4.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 Gene3D G3DSA:1.10.10.60 156 214 1.1E-4 T 29-03-2018 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 Gene3D G3DSA:3.40.50.300 3 118 2.3E-5 T 29-03-2018 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 ProSitePatterns PS00622 LuxR-type HTH domain signature. 754 781 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 Gene3D G3DSA:1.10.10.10 618 797 3.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02665 0563c8238e3bde7e29b3e5a02c7fa637 802 SMART SM00421 737 794 7.9E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Gene3D G3DSA:1.10.3710.10 362 457 5.1E-27 T 29-03-2018 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Pfam PF12002 MgsA AAA+ ATPase C terminal 281 446 4.9E-67 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 SUPERFAMILY SSF48019 266 449 9.64E-72 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 SMART SM00382 64 181 1.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 SUPERFAMILY SSF52540 29 234 5.1E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Gene3D G3DSA:1.20.272.10 265 359 5.5E-40 T 29-03-2018 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 69 164 1.6E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Gene3D G3DSA:1.10.8.60 170 256 1.4E-18 T 29-03-2018 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Gene3D G3DSA:3.40.50.300 21 169 6.5E-22 T 29-03-2018 MSG_RS09865 9688c5a83617f69f4f4a14b32b64f04e 457 Pfam PF16193 AAA C-terminal domain 203 280 6.1E-27 T 29-03-2018 IPR032423 AAA C-terminal domain MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 201 4.2E-56 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 Gene3D G3DSA:3.40.50.620 1 203 3.7E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 202 29.198 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 SUPERFAMILY SSF52374 6 201 9.7E-49 T 29-03-2018 MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 71 7.7E-13 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MSG_RS17020 4a3905d448e417f3500ca66785da651d 210 Pfam PF01467 Cytidylyltransferase-like 10 176 3.6E-31 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MSG_RS07225 8e15c71b2563a267fb2413fd7ba7cb4b 210 SUPERFAMILY SSF56959 26 209 1.37E-57 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 MSG_RS07225 8e15c71b2563a267fb2413fd7ba7cb4b 210 Gene3D G3DSA:2.60.40.1650 31 206 5.8E-36 T 29-03-2018 MSG_RS07225 8e15c71b2563a267fb2413fd7ba7cb4b 210 Pfam PF09203 MspA 37 208 2.2E-45 T 29-03-2018 IPR015286 Porin family, mycobacterial-type MSG_RS01555 d151632fd76b397e878ac92f659fcacf 474 SUPERFAMILY SSF52467 299 472 1.53E-71 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS01555 d151632fd76b397e878ac92f659fcacf 474 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 469 5.5E-175 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MSG_RS01555 d151632fd76b397e878ac92f659fcacf 474 PIRSF PIRSF000204 1 473 2.8E-201 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 MSG_RS01555 d151632fd76b397e878ac92f659fcacf 474 Gene3D G3DSA:3.40.50.1220 298 472 4.3E-82 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SMART SM00387 450 561 6.8E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:1.10.287.130 340 400 8.2E-20 T 29-03-2018 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SMART SM00448 624 737 8.5E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF55874 393 559 1.96E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 539 1.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 558 1.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 514 1.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 500 1.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.450.40 879 969 0.0045 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.565.10 409 563 1.6E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF47384 322 405 2.35E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF13581 Histidine kinase-like ATPase domain 1260 1376 3.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 1066 1251 1.3E-45 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SMART SM00388 337 404 3.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SMART SM00331 1038 1252 8.3E-32 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.40.50.2300 618 744 1.4E-33 T 29-03-2018 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.450.20 745 878 8.8E-19 T 29-03-2018 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.450.20 49 158 6.4E-7 T 29-03-2018 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 338 404 9.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF55785 745 868 2.27E-14 T 29-03-2018 IPR000014 PAS domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 750 871 1.9E-12 T 29-03-2018 IPR000014 PAS domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF55781 194 328 6.98E-10 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.450.40 159 339 1.1E-15 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF55874 1288 1375 8.25E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF00072 Response regulator receiver domain 626 737 9.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.450.40 970 1019 0.015 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF13426 PAS domain 763 869 8.4E-6 T 29-03-2018 IPR000014 PAS domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.60.40.10 1020 1252 5.0E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 SUPERFAMILY SSF52172 618 754 4.7E-38 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Gene3D G3DSA:3.30.565.10 1253 1380 8.6E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00475 d350c86ffb82c4845a2dc6542851bcdc 1380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 560 1.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 Gene3D G3DSA:1.10.287.130 229 300 1.9E-13 T 29-03-2018 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 300 1.6E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SUPERFAMILY SSF158472 191 234 4.45E-5 T 29-03-2018 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 1.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.4E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SMART SM00387 345 455 5.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SMART SM00388 239 304 1.5E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 Gene3D G3DSA:3.30.565.10 318 462 1.7E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SUPERFAMILY SSF55874 323 455 5.37E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 453 5.0E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SUPERFAMILY SSF47384 222 301 2.16E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS21180 a81e7910c379d70c1fe50585df2aead7 463 SMART SM00304 185 238 7.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 509 6.1E-28 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 SUPERFAMILY SSF52518 2 178 2.26E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 Gene3D G3DSA:3.40.50.970 313 516 7.7E-35 T 29-03-2018 MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 165 2.3E-35 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 SUPERFAMILY SSF52518 335 513 9.83E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS22325 5c429fa4916241bb02369b93398bf16b 516 Gene3D G3DSA:3.40.50.970 1 179 7.6E-38 T 29-03-2018 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 Gene3D G3DSA:1.20.1560.10 45 407 7.0E-25 T 29-03-2018 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 SMART SM00382 450 631 5.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 Pfam PF06472 ABC transporter transmembrane region 2 43 356 1.9E-83 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 ProSitePatterns PS00211 ABC transporters family signature. 549 563 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 SUPERFAMILY SSF90123 65 403 3.53E-7 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 SUPERFAMILY SSF52540 412 625 5.61E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 Gene3D G3DSA:3.40.50.300 408 628 2.8E-32 T 29-03-2018 MSG_RS23670 0158eeca1d59e0b4b6bbc47734984dac 637 Pfam PF00005 ABC transporter 443 577 3.9E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS00205 4567b520825031369ae3b435594900bd 105 Gene3D G3DSA:1.10.287.1060 2 100 8.2E-10 T 29-03-2018 MSG_RS00205 4567b520825031369ae3b435594900bd 105 ProDom PD069881 MB0028 RV0027/MT0030 1 105 3.0E-42 T 29-03-2018 MSG_RS00205 4567b520825031369ae3b435594900bd 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 4.4E-26 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SUPERFAMILY SSF88723 16 190 9.81E-55 T 29-03-2018 IPR029060 PIN domain-like MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SMART SM00475 19 281 3.3E-143 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 TIGRFAM TIGR00593 pola: DNA polymerase I 23 911 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SMART SM00474 322 498 7.4E-22 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:3.40.50.1010 21 203 2.5E-69 T 29-03-2018 IPR029060 PIN domain-like MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SUPERFAMILY SSF53098 327 498 8.8E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:3.30.70.370 738 913 5.3E-47 T 29-03-2018 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:3.30.70.370 636 737 2.1E-16 T 29-03-2018 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 684 707 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 775 786 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 738 763 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 797 808 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 714 727 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 634 656 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 829 845 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 PRINTS PR00868 DNA-polymerase family A (pol I) signature 859 872 7.8E-67 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 23 190 5.2E-55 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:1.10.150.20 204 282 1.3E-24 T 29-03-2018 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 192 285 4.4E-26 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SMART SM00482 665 876 3.6E-117 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SMART SM00279 193 228 6.3E-14 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SUPERFAMILY SSF47807 191 304 6.58E-30 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:3.30.420.10 325 522 2.3E-20 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Gene3D G3DSA:1.20.1060.10 523 635 9.1E-24 T 29-03-2018 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 SUPERFAMILY SSF56672 505 911 4.89E-141 T 29-03-2018 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 Pfam PF00476 DNA polymerase family A 531 910 5.4E-144 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS11320 2ae2309ffcd230849a4b04c7d4b23b0c 913 ProSitePatterns PS00447 DNA polymerase family A signature. 738 757 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 SUPERFAMILY SSF52540 20 222 3.6E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 444 630 2.6E-64 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Gene3D G3DSA:2.40.30.10 227 316 1.3E-13 T 29-03-2018 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 SUPERFAMILY SSF50447 231 314 4.29E-13 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 70 85 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 SUPERFAMILY SSF52540 458 632 2.55E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 SUPERFAMILY SSF50465 325 427 2.97E-27 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Pfam PF01583 Adenylylsulphate kinase 462 617 2.8E-63 T 29-03-2018 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Gene3D G3DSA:3.40.50.300 457 634 2.9E-43 T 29-03-2018 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Gene3D G3DSA:2.40.30.10 322 428 2.8E-23 T 29-03-2018 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Gene3D G3DSA:3.40.50.300 17 224 3.9E-38 T 29-03-2018 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 PRINTS PR00315 GTP-binding elongation factor signature 23 36 5.3E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 PRINTS PR00315 GTP-binding elongation factor signature 113 124 5.3E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 PRINTS PR00315 GTP-binding elongation factor signature 77 85 5.3E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 PRINTS PR00315 GTP-binding elongation factor signature 150 159 5.3E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 PRINTS PR00315 GTP-binding elongation factor signature 97 107 5.3E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 22 426 1.2E-143 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 460 634 36.043 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MSG_RS19025 61783f7cf962e3caa41265a02d56cb6c 638 Pfam PF00009 Elongation factor Tu GTP binding domain 21 215 1.0E-37 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 SUPERFAMILY SSF47203 198 333 2.26E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 Gene3D G3DSA:1.10.540.10 20 97 4.1E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 SUPERFAMILY SSF56645 1 190 1.83E-25 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 325 2.0E-14 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 Gene3D G3DSA:1.20.140.10 192 336 6.7E-21 T 29-03-2018 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 99 4.7E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22495 dd3bb2e986dff89f94861873922a8f28 337 Gene3D G3DSA:2.40.110.10 98 191 4.0E-5 T 29-03-2018 MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 Pfam PF12867 DinB superfamily 11 141 1.2E-22 T 29-03-2018 IPR024775 DinB-like domain MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 SUPERFAMILY SSF109854 3 137 7.02E-16 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 Pfam PF03781 Sulfatase-modifying factor enzyme 1 170 426 9.4E-60 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 429 47.775 T 29-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 SUPERFAMILY SSF56436 171 429 6.36E-69 T 29-03-2018 IPR016187 C-type lectin fold MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 Gene3D G3DSA:1.20.120.450 1 150 7.6E-18 T 29-03-2018 MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 Gene3D G3DSA:3.90.1580.10 161 436 1.1E-63 T 29-03-2018 MSG_RS23350 29b864020a82e1057305b79ef2d94255 436 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 7 426 9.9E-124 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 SUPERFAMILY SSF55347 153 315 4.03E-45 T 29-03-2018 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 5 341 37.915 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 136 1.5E-21 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 SUPERFAMILY SSF51735 5 177 2.06E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 SMART SM00859 6 143 3.1E-40 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 Gene3D G3DSA:3.40.50.720 1 159 1.4E-43 T 29-03-2018 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 Gene3D G3DSA:3.30.360.10 160 315 5.7E-53 T 29-03-2018 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 5 347 2.0E-113 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 148 164 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11495 4b50e05aeb311d3c469801f137b99119 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 171 318 2.4E-23 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 128 273 7.7E-64 T 29-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 Gene3D G3DSA:3.40.50.720 2 142 1.2E-13 T 29-03-2018 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 117 1.2E-8 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 SMART SM00859 7 120 1.1E-5 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 6 298 1.3E-136 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 SUPERFAMILY SSF51735 7 152 3.94E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 Gene3D G3DSA:3.30.360.10 143 273 1.4E-68 T 29-03-2018 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 307 143.102 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 PIRSF PIRSF015689 2 303 1.4E-136 T 29-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 MSG_RS22450 044c1a7e975b3041f7b1ba1b2f9ebfe9 307 SUPERFAMILY SSF55347 128 273 2.55E-59 T 29-03-2018 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Gene3D G3DSA:3.30.310.50 374 444 4.9E-23 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 364 1.5E-27 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Gene3D G3DSA:3.40.120.10 263 373 1.5E-26 T 29-03-2018 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 4.5E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 4.5E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 4.5E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 2.9E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.4E-186 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 43.755 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Gene3D G3DSA:3.40.120.10 155 262 1.5E-27 T 29-03-2018 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 SUPERFAMILY SSF55957 358 443 6.28E-24 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 SUPERFAMILY SSF53738 3 180 1.92E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 2.0E-41 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 SUPERFAMILY SSF53738 257 365 8.63E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 253 4.7E-19 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 SUPERFAMILY SSF53738 158 255 2.9E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS04920 e66ca8156d6b4c343ad5108b165d9651 445 Gene3D G3DSA:3.40.120.10 2 140 1.1E-43 T 29-03-2018 MSG_RS10045 43790b90b5317b9c184518393bfc3ac0 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS10045 43790b90b5317b9c184518393bfc3ac0 251 SUPERFAMILY SSF52096 12 240 3.89E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS10045 43790b90b5317b9c184518393bfc3ac0 251 Gene3D G3DSA:3.90.226.10 2 245 6.0E-62 T 29-03-2018 MSG_RS10045 43790b90b5317b9c184518393bfc3ac0 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 235 2.0E-46 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS08475 68cb406dcb66fba0bcfbd6306aae2f56 156 SUPERFAMILY SSF55729 13 148 9.92E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS08475 68cb406dcb66fba0bcfbd6306aae2f56 156 Pfam PF13673 Acetyltransferase (GNAT) domain 48 146 2.2E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS08475 68cb406dcb66fba0bcfbd6306aae2f56 156 Gene3D G3DSA:3.40.630.30 1 153 1.3E-24 T 29-03-2018 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 SUPERFAMILY SSF51569 64 372 2.75E-94 T 29-03-2018 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 SMART SM00917 474 605 2.3E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 Gene3D G3DSA:3.20.20.150 480 577 0.013 T 29-03-2018 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 Pfam PF08502 LeuA allosteric (dimerisation) domain 474 604 1.6E-31 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 45 606 1.1E-300 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 SUPERFAMILY SSF89000 440 489 3.45E-15 T 29-03-2018 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 82 98 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 Pfam PF00682 HMGL-like 75 355 1.4E-77 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 Gene3D G3DSA:3.20.20.70 52 428 7.7E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 SUPERFAMILY SSF110921 496 604 1.02E-36 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 285 298 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS23410 8810f521f7018927afd7638299a270bd 606 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 46 606 54.934 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 SUPERFAMILY SSF55021 8 79 9.16E-22 T 29-03-2018 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 Gene3D G3DSA:3.30.70.260 1 92 1.8E-25 T 29-03-2018 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 Gene3D G3DSA:3.30.70.1150 93 165 5.3E-30 T 29-03-2018 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 7 162 1.1E-61 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 Pfam PF13710 ACT domain 16 78 2.0E-17 T 29-03-2018 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 SUPERFAMILY SSF55021 84 165 1.83E-26 T 29-03-2018 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 Pfam PF10369 Small subunit of acetolactate synthase 89 162 4.1E-28 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MSG_RS07765 b01f1a3860a3576ff400a23cb3cf0a85 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 80 9.0E-36 T 29-03-2018 MSG_RS23590 b2563a9573627c4e03eba432de02f512 128 Gene3D G3DSA:2.30.110.10 6 115 1.5E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS23590 b2563a9573627c4e03eba432de02f512 128 SUPERFAMILY SSF50475 11 115 9.73E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS23590 b2563a9573627c4e03eba432de02f512 128 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 62 5.1E-8 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS23590 b2563a9573627c4e03eba432de02f512 128 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 126 9.6E-42 T 29-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 Pfam PF00501 AMP-binding enzyme 26 489 2.4E-67 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 SUPERFAMILY SSF56801 19 613 6.15E-88 T 29-03-2018 MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 Gene3D G3DSA:3.30.300.30 485 610 1.1E-11 T 29-03-2018 MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 Gene3D G3DSA:3.40.50.980 18 185 2.5E-25 T 29-03-2018 MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 Gene3D G3DSA:3.40.50.980 186 357 4.8E-29 T 29-03-2018 MSG_RS24170 1f1cf898631bd98e71e0c9a640a330a5 630 Gene3D G3DSA:2.30.38.10 392 483 4.8E-17 T 29-03-2018 MSG_RS19920 58ae24b68342e3ac273330a7b32b0349 420 Gene3D G3DSA:3.20.20.140 1 377 3.0E-64 T 29-03-2018 MSG_RS19920 58ae24b68342e3ac273330a7b32b0349 420 Pfam PF04909 Amidohydrolase 77 372 1.9E-20 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS19920 58ae24b68342e3ac273330a7b32b0349 420 SUPERFAMILY SSF51556 9 36 9.64E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS19920 58ae24b68342e3ac273330a7b32b0349 420 SUPERFAMILY SSF51556 67 383 9.64E-68 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 SUPERFAMILY SSF46689 10 76 5.34E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 Gene3D G3DSA:1.10.10.60 11 49 6.3E-18 T 29-03-2018 MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 4.6E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01595 b84f5aa3360ead96b1d34a94a139dd2d 179 Gene3D G3DSA:1.10.10.60 50 171 1.8E-10 T 29-03-2018 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Pfam PF00501 AMP-binding enzyme 13 434 4.1E-67 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 SUPERFAMILY SSF56801 5 537 7.06E-112 T 29-03-2018 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 525 6.1E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Gene3D G3DSA:3.30.300.30 438 549 9.3E-25 T 29-03-2018 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Gene3D G3DSA:2.30.38.10 351 434 2.4E-7 T 29-03-2018 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Gene3D G3DSA:3.40.50.980 5 175 4.1E-41 T 29-03-2018 MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS22360 a20854866d427f87b8a41c76dded2c3b 550 Gene3D G3DSA:3.40.50.980 176 350 3.1E-26 T 29-03-2018 MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 SUPERFAMILY SSF51735 3 207 4.24E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 7.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 7.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 7.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.2E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 3.2E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.2E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.2E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.2E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 Pfam PF00106 short chain dehydrogenase 9 186 2.3E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11805 858759dd4de9141a1cfef50f207be6c4 245 Gene3D G3DSA:3.40.50.720 1 237 8.3E-46 T 29-03-2018 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 87 110 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 79 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 ProSitePatterns PS01081 TetR-type HTH domain signature. 78 109 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 Gene3D G3DSA:1.10.10.60 100 210 1.2E-8 T 29-03-2018 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 Gene3D G3DSA:1.10.10.60 45 99 4.0E-19 T 29-03-2018 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 66 112 7.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12500 40763750d02954d6a6d92ed0ca68c3cc 233 SUPERFAMILY SSF46689 53 118 4.94E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 76.97 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 8.9E-46 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 3.6E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 3.6E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 3.6E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.6E-27 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 1.9E-114 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 Gene3D G3DSA:3.40.50.1370 1 140 2.4E-49 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 SUPERFAMILY SSF53671 2 305 1.7E-99 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 Gene3D G3DSA:3.40.50.1370 141 305 2.2E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 4.0E-53 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 3.0E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 3.0E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 3.0E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 3.0E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11515 09bf29e6b4d6ee428b4ca396b229b1c5 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 3.0E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 Gene3D G3DSA:3.30.499.10 1 160 1.0E-32 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 Gene3D G3DSA:3.30.499.10 328 468 5.9E-50 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 SUPERFAMILY SSF53732 4 468 1.14E-139 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 Pfam PF00330 Aconitase family (aconitate hydratase) 10 460 3.4E-129 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 Gene3D G3DSA:3.40.1060.10 161 294 9.4E-36 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 215 228 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 139 154 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 292 306 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 402 415 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 201 214 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 346 357 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 114 122 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 PRINTS PR00415 Aconitase family signature 125 138 1.1E-34 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10145 a864309249fe2302702581e0f7e3e78f 468 ProSitePatterns PS00450 Aconitase family signature 1. 342 358 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 Pfam PF13410 Glutathione S-transferase, C-terminal domain 185 255 1.2E-12 T 29-03-2018 MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 SUPERFAMILY SSF52833 21 93 3.02E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 PIRSF PIRSF015753 2 304 1.4E-109 T 29-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 Gene3D G3DSA:3.40.30.10 14 168 1.9E-22 T 29-03-2018 MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 Pfam PF13409 Glutathione S-transferase, N-terminal domain 44 136 2.7E-9 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 SUPERFAMILY SSF47616 157 321 1.95E-34 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MSG_RS20775 d5adb71fab6b34dcb05274d5c3fe659f 332 Gene3D G3DSA:1.20.1050.10 169 309 2.7E-44 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 646 936 4.2E-97 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00826 1001 1162 1.1E-29 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1853 2032 4.8E-41 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF51735 1622 1779 2.35E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 372 489 3.1E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF08659 KR domain 1853 2030 5.5E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF00698 Acyl transferase domain 644 953 1.1E-93 T 29-03-2018 IPR014043 Acyl transferase MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1534 1600 4.5E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.30.70.250 782 820 9.0E-13 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 492 598 1.1E-20 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.47.10 379 540 4.5E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF14765 Polyketide synthase dehydratase 1001 1275 3.6E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF47336 2113 2196 5.23E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF52151 831 932 3.92E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF52151 643 768 3.92E-60 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF50129 1513 1648 3.62E-34 T 29-03-2018 IPR011032 GroES-like MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.90.180.10 1493 1642 5.7E-37 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:1.10.1200.10 17 104 5.3E-12 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF53901 517 538 2.74E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF53901 114 485 2.74E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF00550 Phosphopantetheine attachment site 30 96 7.3E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF00550 Phosphopantetheine attachment site 2119 2185 1.5E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00823 Phosphopantetheine attachment site 2121 2189 4.6E-10 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00823 Phosphopantetheine attachment site 29 100 1.4E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.47.10 110 376 1.4E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 277 293 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00829 1517 1829 3.0E-155 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF55048 766 830 7.19E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.366.10 639 781 5.4E-40 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF00107 Zinc-binding dehydrogenase 1658 1748 3.4E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.10.129.10 1015 1125 3.1E-9 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SMART SM00825 Beta-ketoacyl synthase 117 542 2.0E-213 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF51735 1852 2079 5.3E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF51735 1289 1491 7.88E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 SUPERFAMILY SSF47336 24 129 4.06E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.366.10 821 939 6.8E-22 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.50.720 1842 2081 2.2E-38 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 115 364 2.1E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:1.10.1200.10 2108 2198 2.1E-14 T 29-03-2018 MSG_RS08010 4c8dac8a05ac7425585e05fb74f97977 2200 Gene3D G3DSA:3.40.50.720 1643 1815 4.5E-32 T 29-03-2018 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 Pfam PF00672 HAMP domain 278 325 1.4E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 SUPERFAMILY SSF158472 279 326 1.15E-5 T 29-03-2018 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 SMART SM00304 277 329 2.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 358 490 9.0E-18 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 Gene3D G3DSA:3.30.70.1230 338 531 7.5E-35 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 SUPERFAMILY SSF55073 352 531 4.08E-41 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS09835 44491037a5e09bd0223a4fddce3343d6 534 SMART SM00044 325 515 7.7E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Pfam PF05697 Bacterial trigger factor protein (TF) 2 144 1.7E-39 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 TIGRFAM TIGR00115 tig: trigger factor 12 413 5.0E-118 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Gene3D G3DSA:1.10.3120.10 224 396 7.5E-41 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Gene3D G3DSA:1.10.4030.10 119 159 0.25 T 29-03-2018 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 217 4.9E-5 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Gene3D G3DSA:3.30.70.1050 1 118 3.2E-33 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 418 1.4E-38 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Hamap MF_00303 Trigger factor [tig]. 1 424 19.13 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 Gene3D G3DSA:3.10.50.40 160 223 1.2E-6 T 29-03-2018 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 SUPERFAMILY SSF102735 2 131 1.57E-33 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 SUPERFAMILY SSF54534 133 244 7.65E-21 T 29-03-2018 MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 SUPERFAMILY SSF109998 246 436 1.08E-38 T 29-03-2018 IPR027304 Trigger factor/SurA domain MSG_RS17225 c7e6d6c20531f59464d3992077892cbb 470 PIRSF PIRSF003095 1 445 1.7E-121 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MSG_RS01615 72e5611c4c280143dfff7c9b666ce27f 306 Pfam PF00296 Luciferase-like monooxygenase 1 211 1.6E-46 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS01615 72e5611c4c280143dfff7c9b666ce27f 306 Gene3D G3DSA:3.20.20.30 1 306 2.2E-65 T 29-03-2018 MSG_RS01615 72e5611c4c280143dfff7c9b666ce27f 306 SUPERFAMILY SSF51679 1 303 6.93E-62 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS01615 72e5611c4c280143dfff7c9b666ce27f 306 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 26 282 5.5E-80 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 Pfam PF01642 Methylmalonyl-CoA mutase 51 580 5.3E-226 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 SUPERFAMILY SSF52242 586 750 1.18E-57 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 397 422 - T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 Pfam PF02310 B12 binding domain 622 736 1.3E-14 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 619 748 2.6E-62 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 50 587 4.0E-280 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 SUPERFAMILY SSF51703 43 582 8.37E-210 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 Gene3D G3DSA:3.40.50.280 603 750 6.6E-37 T 29-03-2018 MSG_RS10730 b3cc0e2fdec199346623ceb032ec2d8e 754 Gene3D G3DSA:3.20.20.240 50 582 8.9E-233 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS01375 05c3931ef1cd1c2e5c3042d4989c507e 107 Pfam PF00550 Phosphopantetheine attachment site 41 100 2.0E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS01375 05c3931ef1cd1c2e5c3042d4989c507e 107 ProSitePatterns PS00012 Phosphopantetheine attachment site. 60 75 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS01375 05c3931ef1cd1c2e5c3042d4989c507e 107 SUPERFAMILY SSF47336 29 105 7.98E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS01375 05c3931ef1cd1c2e5c3042d4989c507e 107 Gene3D G3DSA:1.10.1200.10 25 107 8.9E-11 T 29-03-2018 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 Pfam PF07670 Nucleoside recognition 295 388 5.9E-13 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 Pfam PF07670 Nucleoside recognition 464 607 6.6E-24 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 Gene3D G3DSA:3.40.50.300 15 186 7.6E-25 T 29-03-2018 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 Pfam PF07664 Ferrous iron transport protein B C terminus 407 458 5.0E-16 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 20 40 7.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 41 59 7.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 SUPERFAMILY SSF52540 18 181 5.52E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08090 6830c77c4875af9f160287af2f67a632 637 Pfam PF02421 Ferrous iron transport protein B 19 176 3.6E-47 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 SUPERFAMILY SSF50249 2 126 5.83E-50 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 SMART SM01383 42 119 5.5E-42 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Gene3D G3DSA:2.30.30.30 120 196 7.4E-29 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Gene3D G3DSA:4.10.950.10 198 273 1.6E-30 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Gene3D G3DSA:2.40.50.140 1 115 2.3E-45 T 29-03-2018 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 2.0E-129 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 SUPERFAMILY SSF50104 127 271 1.08E-55 T 29-03-2018 IPR008991 Translation protein SH3-like domain MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 4.2E-55 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 1.5E-33 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 PIRSF PIRSF002158 4 275 1.5E-94 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 SMART SM01382 125 253 6.0E-89 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS04475 de862b9d4ecafc89239280107cb1846a 280 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.185 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MSG_RS11380 1f796744f3b267f8bc665fb895573070 480 Pfam PF07690 Major Facilitator Superfamily 28 423 3.3E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS11380 1f796744f3b267f8bc665fb895573070 480 Gene3D G3DSA:1.20.1250.20 269 479 4.5E-15 T 29-03-2018 MSG_RS11380 1f796744f3b267f8bc665fb895573070 480 Gene3D G3DSA:1.20.1250.20 14 207 3.1E-18 T 29-03-2018 MSG_RS11380 1f796744f3b267f8bc665fb895573070 480 SUPERFAMILY SSF103473 257 470 6.02E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS11380 1f796744f3b267f8bc665fb895573070 480 SUPERFAMILY SSF103473 23 204 6.02E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 334 346 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 Pfam PF00571 CBS domain 132 180 2.2E-10 T 29-03-2018 IPR000644 CBS domain MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 Pfam PF00571 CBS domain 188 241 3.4E-8 T 29-03-2018 IPR000644 CBS domain MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 47 504 3.4E-180 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SMART SM01240 46 522 3.0E-302 T 29-03-2018 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 47 522 1.7E-151 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SUPERFAMILY SSF51412 41 129 1.7E-111 T 29-03-2018 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SUPERFAMILY SSF51412 255 526 1.7E-111 T 29-03-2018 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SUPERFAMILY SSF54631 132 242 5.43E-31 T 29-03-2018 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 47 535 83.711 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 PIRSF PIRSF000130 38 536 3.8E-199 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 Gene3D G3DSA:3.20.20.70 37 517 2.0E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SMART SM00116 135 183 3.8E-9 T 29-03-2018 IPR000644 CBS domain MSG_RS05115 1114fd5aa5c9d1f7c50c1cc42a4dd33b 536 SMART SM00116 196 244 3.9E-7 T 29-03-2018 IPR000644 CBS domain MSG_RS04665 838be606769c192dabaa509b8629cf67 329 Gene3D G3DSA:3.40.50.720 124 294 2.4E-51 T 29-03-2018 MSG_RS04665 838be606769c192dabaa509b8629cf67 329 SUPERFAMILY SSF51735 109 292 8.35E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04665 838be606769c192dabaa509b8629cf67 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 291 1.9E-52 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MSG_RS04665 838be606769c192dabaa509b8629cf67 329 Gene3D G3DSA:3.40.50.720 4 123 5.0E-22 T 29-03-2018 MSG_RS04665 838be606769c192dabaa509b8629cf67 329 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MSG_RS04665 838be606769c192dabaa509b8629cf67 329 SUPERFAMILY SSF52283 4 139 1.06E-16 T 29-03-2018 MSG_RS04665 838be606769c192dabaa509b8629cf67 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 46 323 2.5E-12 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MSG_RS00545 3b6287366a2f13815758897ec131f559 351 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 220 322 4.2E-8 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MSG_RS00545 3b6287366a2f13815758897ec131f559 351 Pfam PF02558 Ketopantoate reductase PanE/ApbA 10 166 4.8E-19 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MSG_RS00545 3b6287366a2f13815758897ec131f559 351 SUPERFAMILY SSF51735 10 154 3.74E-7 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00545 3b6287366a2f13815758897ec131f559 351 SUPERFAMILY SSF48179 202 321 1.7E-6 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS00545 3b6287366a2f13815758897ec131f559 351 Gene3D G3DSA:3.40.50.720 3 200 1.4E-16 T 29-03-2018 MSG_RS00545 3b6287366a2f13815758897ec131f559 351 Gene3D G3DSA:1.10.1040.10 201 324 4.9E-13 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 944 24.893 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Gene3D G3DSA:3.90.1150.10 343 445 8.7E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Gene3D G3DSA:3.90.1150.10 760 892 3.0E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 10 938 0.0 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 SUPERFAMILY SSF53383 469 874 2.42E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 SUPERFAMILY SSF53383 917 940 2.42E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Gene3D G3DSA:3.40.640.10 97 342 9.6E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 SUPERFAMILY SSF53383 10 442 1.73E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Gene3D G3DSA:3.40.640.10 521 759 3.8E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Pfam PF02347 Glycine cleavage system P-protein 9 442 6.7E-181 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS12845 472d278228146605fd5cf1a961b6698c 945 Pfam PF02347 Glycine cleavage system P-protein 469 724 4.4E-9 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS02635 cff2f4b257a0dcbec8009d33affe97f8 251 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 225 1.0E-26 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS02635 cff2f4b257a0dcbec8009d33affe97f8 251 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 130 1.6E-20 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MSG_RS02635 cff2f4b257a0dcbec8009d33affe97f8 251 Pfam PF07398 MDMPI C-terminal domain 142 243 4.9E-18 T 29-03-2018 IPR010872 MDMPI C-terminal MSG_RS02635 cff2f4b257a0dcbec8009d33affe97f8 251 Gene3D G3DSA:1.20.120.450 1 136 7.1E-17 T 29-03-2018 MSG_RS02635 cff2f4b257a0dcbec8009d33affe97f8 251 SUPERFAMILY SSF109854 4 135 8.24E-7 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS04550 a3533c2ceb26d581ccbf9332eaf67c76 153 Gene3D G3DSA:2.30.110.10 18 153 2.3E-13 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS04550 a3533c2ceb26d581ccbf9332eaf67c76 153 SUPERFAMILY SSF50475 26 148 3.23E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS04550 a3533c2ceb26d581ccbf9332eaf67c76 153 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 30 146 3.1E-24 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 20 80 13.358 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 SUPERFAMILY SSF116842 14 73 1.44E-16 T 29-03-2018 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 Pfam PF02609 Exonuclease VII small subunit 21 71 4.1E-17 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 21 61 5.0E-15 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 21 75 4.3E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 PIRSF PIRSF006488 9 81 3.4E-25 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19520 7f1a2233ffad41798969e7e1afa766c9 82 Gene3D G3DSA:1.10.287.1040 18 80 3.5E-19 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 407 2.2E-113 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 SUPERFAMILY SSF102645 177 412 2.35E-62 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 382 9.9E-66 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 SUPERFAMILY SSF52507 2 171 5.36E-55 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 Pfam PF02441 Flavoprotein 4 169 8.5E-39 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 Gene3D G3DSA:3.40.50.1950 1 180 2.0E-49 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MSG_RS10265 c1d03acd679cce78a2f7547d3b2e06d4 416 Gene3D G3DSA:3.40.50.10300 181 416 7.5E-64 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 SUPERFAMILY SSF52540 155 306 7.26E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 SUPERFAMILY SSF52540 32 119 7.26E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 Gene3D G3DSA:2.20.28.20 1 30 7.3E-4 T 29-03-2018 MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 Pfam PF13191 AAA ATPase domain 41 222 4.3E-24 T 29-03-2018 MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 SMART SM00382 63 247 0.0089 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 Gene3D G3DSA:1.25.40.10 390 862 5.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS03975 a0ed0708c2ee746b26377eed8bb804e9 863 Gene3D G3DSA:3.40.50.300 31 227 3.3E-9 T 29-03-2018 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 Gene3D G3DSA:3.40.50.2300 21 153 1.4E-37 T 29-03-2018 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 Pfam PF00486 Transcriptional regulatory protein, C terminal 181 252 7.0E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 SUPERFAMILY SSF46894 156 253 4.25E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 SMART SM00862 178 252 3.5E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 Pfam PF00072 Response regulator receiver domain 33 142 4.2E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 Gene3D G3DSA:1.10.10.10 154 256 1.1E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 SUPERFAMILY SSF52172 27 156 5.55E-41 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS19790 b63ebfb6542cc5aefdb2b1ed745d3b36 256 SMART SM00448 31 142 7.4E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 470 488 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 613 628 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 524 543 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 631 653 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 554 574 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 520 1.9E-54 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 Gene3D G3DSA:3.40.50.1820 419 707 1.0E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 SUPERFAMILY SSF50993 8 435 3.66E-83 T 29-03-2018 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 Pfam PF00326 Prolyl oligopeptidase family 486 700 2.3E-57 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 Gene3D G3DSA:2.130.10.120 79 418 5.3E-54 T 29-03-2018 MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 SUPERFAMILY SSF53474 438 684 5.36E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09425 b1981665aa7c66ec698d542642d05900 709 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 11 428 5.6E-108 T 29-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 Pfam PF00557 Metallopeptidase family M24 22 257 1.2E-39 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 Hamap MF_01974 Methionine aminopeptidase [map]. 13 266 35.823 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 SUPERFAMILY SSF55920 16 264 4.58E-73 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 220 2.4E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 91 2.4E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.4E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 101 117 2.4E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 265 1.2E-76 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS04705 9765b4fac496a2bf09610e31dbdb07df 266 Gene3D G3DSA:3.90.230.10 10 266 5.3E-66 T 29-03-2018 MSG_RS10195 94866c0f0ac5f71c51629cc9c6e75ecc 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 107 2.7E-16 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MSG_RS10195 94866c0f0ac5f71c51629cc9c6e75ecc 116 Gene3D G3DSA:3.30.750.24 2 115 1.5E-16 T 29-03-2018 IPR002645 STAS domain MSG_RS10195 94866c0f0ac5f71c51629cc9c6e75ecc 116 Pfam PF01740 STAS domain 13 110 9.2E-11 T 29-03-2018 IPR002645 STAS domain MSG_RS10195 94866c0f0ac5f71c51629cc9c6e75ecc 116 SUPERFAMILY SSF52091 13 112 1.81E-18 T 29-03-2018 IPR002645 STAS domain MSG_RS04075 973b820aa10fb34c75fb9f947ed89656 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04075 973b820aa10fb34c75fb9f947ed89656 55 SUPERFAMILY SSF57829 5 55 7.94E-20 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MSG_RS04075 973b820aa10fb34c75fb9f947ed89656 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 6 55 2.4E-21 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04075 973b820aa10fb34c75fb9f947ed89656 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 19.619 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04075 973b820aa10fb34c75fb9f947ed89656 55 Pfam PF00471 Ribosomal protein L33 10 55 2.3E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 SUPERFAMILY SSF52833 3 160 9.12E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 7.5E-15 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 7.5E-15 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 7.5E-15 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 Pfam PF00255 Glutathione peroxidase 6 109 4.7E-36 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 PIRSF PIRSF000303 1 162 1.8E-59 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MSG_RS06425 7e99ca9ef55156e5a9e9f585fab2b1c1 162 Gene3D G3DSA:3.40.30.10 2 162 1.3E-45 T 29-03-2018 MSG_RS20100 8d496f941b5ca0e96dc0e1b76c960668 215 Gene3D G3DSA:2.60.120.590 40 212 6.0E-32 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MSG_RS20100 8d496f941b5ca0e96dc0e1b76c960668 215 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 105 210 9.7E-14 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MSG_RS20100 8d496f941b5ca0e96dc0e1b76c960668 215 SUPERFAMILY SSF51197 44 210 7.55E-42 T 29-03-2018 MSG_RS15785 90143b4ee9d3208ad80abc26e5411f80 235 Gene3D G3DSA:3.30.565.40 56 147 3.1E-5 T 29-03-2018 MSG_RS15785 90143b4ee9d3208ad80abc26e5411f80 235 Pfam PF11738 Protein of unknown function (DUF3298) 151 223 6.6E-7 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.50.720 1498 1610 8.8E-15 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 1468 1645 1.91E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF52151 552 681 1.26E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF52151 745 840 1.26E-68 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3540 3561 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF55048 2709 2770 6.15E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00825 Beta-ketoacyl synthase 2060 2484 1.6E-207 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00825 Beta-ketoacyl synthase 36 455 3.8E-206 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF50129 3408 3549 8.96E-26 T 29-03-2018 IPR011032 GroES-like MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 1136 1343 3.94E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 193 209 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF47336 1963 2073 1.2E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.90.180.10 1364 1497 1.1E-31 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 3729 3968 1.51E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00826 2946 3106 1.6E-77 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00826 920 1084 7.7E-75 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2313 2432 5.7E-44 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 288 403 1.9E-42 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.50.720 3728 3986 3.5E-48 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.366.10 2761 2883 1.6E-26 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1388 1443 1.8E-4 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00823 Phosphopantetheine attachment site 1967 2039 2.7E-29 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00823 Phosphopantetheine attachment site 4019 4091 1.6E-28 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 406 519 6.0E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2435 2549 1.8E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM01294 4020 4087 4.7E-6 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM01294 1968 2035 2.3E-6 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF53901 2054 2422 5.89E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.47.10 295 453 8.3E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.47.10 2320 2482 4.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.366.10 2582 2720 3.0E-44 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.366.10 552 692 1.6E-45 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF47336 4012 4103 6.81E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:1.10.1200.10 4004 4100 4.4E-19 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF14765 Polyketide synthase dehydratase 2946 3223 2.8E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF14765 Polyketide synthase dehydratase 920 1197 2.1E-50 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00698 Acyl transferase domain 2584 2898 6.0E-57 T 29-03-2018 IPR014043 Acyl transferase MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00698 Acyl transferase domain 554 874 4.0E-91 T 29-03-2018 IPR014043 Acyl transferase MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF13602 Zinc-binding dehydrogenase 1543 1673 1.4E-18 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF13602 Zinc-binding dehydrogenase 3587 3717 6.1E-20 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1683 1861 8.3E-58 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3731 3911 6.4E-61 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2058 2305 1.2E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 280 4.2E-87 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.30.70.250 693 738 3.8E-17 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.30.70.250 2721 2760 4.3E-18 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:1.10.1200.10 1960 2054 4.5E-20 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00829 1369 1674 3.8E-159 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00829 3412 3718 9.1E-170 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.90.180.10 3405 3721 7.0E-59 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 3233 3386 1.03E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2218 2234 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 3512 3688 2.04E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.90.180.10 1611 1666 0.093 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF52151 2763 2866 3.4E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF52151 2583 2704 3.4E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1994 2009 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.47.10 26 292 6.4E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.47.10 2055 2317 7.2E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.50.720 1667 1929 8.3E-47 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Gene3D G3DSA:3.40.366.10 739 850 1.4E-22 T 29-03-2018 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF08659 KR domain 3731 3909 5.8E-60 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF08659 KR domain 1683 1859 4.5E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00550 Phosphopantetheine attachment site 4021 4086 2.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 Pfam PF00550 Phosphopantetheine attachment site 1969 2035 2.5E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2586 2881 5.2E-111 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 556 855 7.3E-121 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF50129 1366 1505 4.25E-23 T 29-03-2018 IPR011032 GroES-like MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4046 4061 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF51735 1680 1939 1.44E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF53901 31 395 3.89E-100 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1496 1517 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MSG_RS14535 53a4e088fbcd8fe6939023a8d96e861b 4172 SUPERFAMILY SSF55048 679 744 8.76E-12 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 204 7.8E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS20270 ae2651816b4179e33da772df87846806 388 PIRSF PIRSF016578 237 379 4.5E-6 T 29-03-2018 MSG_RS20270 ae2651816b4179e33da772df87846806 388 PIRSF PIRSF016578 8 197 3.1E-6 T 29-03-2018 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Gene3D G3DSA:1.20.140.10 221 388 6.2E-38 T 29-03-2018 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Gene3D G3DSA:2.40.110.10 123 220 2.3E-27 T 29-03-2018 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 379 1.8E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS20270 ae2651816b4179e33da772df87846806 388 SUPERFAMILY SSF56645 5 244 7.85E-62 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 3.9E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS20270 ae2651816b4179e33da772df87846806 388 Gene3D G3DSA:1.10.540.10 1 121 2.4E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS20270 ae2651816b4179e33da772df87846806 388 SUPERFAMILY SSF47203 230 386 5.64E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16535 a1053dc3a5f26f479b5b4c828c4abdf7 447 Pfam PF02470 MlaD protein 38 111 4.5E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS16535 a1053dc3a5f26f479b5b4c828c4abdf7 447 SUPERFAMILY SSF58104 160 330 4.58E-5 T 29-03-2018 MSG_RS16535 a1053dc3a5f26f479b5b4c828c4abdf7 447 Gene3D G3DSA:1.20.120.20 128 317 2.4E-6 T 29-03-2018 MSG_RS16535 a1053dc3a5f26f479b5b4c828c4abdf7 447 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 301 3.2E-72 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS12825 603b3de4738b44e9ccff39a51831cc11 151 SUPERFAMILY SSF49879 39 138 8.03E-32 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS12825 603b3de4738b44e9ccff39a51831cc11 151 Gene3D G3DSA:2.60.200.20 19 140 4.6E-30 T 29-03-2018 MSG_RS12825 603b3de4738b44e9ccff39a51831cc11 151 Pfam PF00498 FHA domain 69 131 1.2E-19 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12825 603b3de4738b44e9ccff39a51831cc11 151 SMART SM00240 67 117 1.2E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12545 6e1b89998cf76972cfbd9a5e0de1140c 290 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 236 3.6E-31 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS12545 6e1b89998cf76972cfbd9a5e0de1140c 290 Gene3D G3DSA:3.90.226.10 1 289 3.5E-50 T 29-03-2018 MSG_RS12545 6e1b89998cf76972cfbd9a5e0de1140c 290 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS12545 6e1b89998cf76972cfbd9a5e0de1140c 290 SUPERFAMILY SSF52096 7 266 1.62E-54 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 Gene3D G3DSA:3.40.50.720 1 271 7.7E-46 T 29-03-2018 MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 SUPERFAMILY SSF51735 2 252 2.26E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 Pfam PF00106 short chain dehydrogenase 2 193 2.5E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.1E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.1E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13190 66daab75e179939d72990b4b16c436a7 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS03425 062197377b02e9cd538e137facb14410 284 Gene3D G3DSA:3.60.110.10 1 279 4.3E-65 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS03425 062197377b02e9cd538e137facb14410 284 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 146 166 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site MSG_RS03425 062197377b02e9cd538e137facb14410 284 SUPERFAMILY SSF56317 1 269 3.27E-64 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS03425 062197377b02e9cd538e137facb14410 284 Pfam PF00795 Carbon-nitrogen hydrolase 2 262 2.0E-37 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF52151 284 367 4.71E-20 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF52151 34 189 4.71E-20 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.10.129.10 1202 1337 4.2E-21 T 29-03-2018 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.40.47.10 2835 3004 2.4E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2827 2952 3.5E-27 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Pfam PF08354 Domain of unknown function (DUF1729) 846 898 5.0E-21 T 29-03-2018 IPR013565 Domain of unknown function DUF1729 GO:0004318|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2586 2817 8.1E-36 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 435 453 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 730 748 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 840 864 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1434 1453 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 540 558 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1225 1247 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1247 1268 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 409 429 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 560 579 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1332 1351 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1353 1376 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 PRINTS PR01483 Fatty acid synthase signature 1470 1491 8.7E-112 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF51412 397 667 5.86E-18 T 29-03-2018 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.40.366.10 1338 1724 5.5E-52 T 29-03-2018 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.40.47.10 2447 2831 7.7E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF53901 2788 3002 9.6E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF52151 1571 1592 1.24E-29 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF52151 1632 1712 1.24E-29 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF52151 1339 1483 1.24E-29 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF54637 1225 1334 2.29E-21 T 29-03-2018 IPR029069 HotDog domain MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.20.20.70 391 915 1.5E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.10.129.10 1057 1201 2.8E-5 T 29-03-2018 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Pfam PF01575 MaoC like domain 1207 1322 2.4E-28 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2722 2738 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF53901 2596 2826 1.15E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Pfam PF00698 Acyl transferase domain 1341 1544 3.0E-38 T 29-03-2018 IPR014043 Acyl transferase MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 37 373 1.1E-4 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 SUPERFAMILY SSF51735 2127 2368 9.34E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.40.366.10 34 374 7.9E-31 T 29-03-2018 MSG_RS17635 4eb720133ec544dc42a9ab2b97d50932 3083 Gene3D G3DSA:3.40.50.720 2113 2369 7.4E-11 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 Gene3D G3DSA:3.40.1110.10 349 457 6.6E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 337 351 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 550 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 466 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 488 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 6.8E-18 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 110 597 8.3E-59 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 339 345 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 SUPERFAMILY SSF81653 142 237 1.31E-23 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 SUPERFAMILY SSF81665 238 331 3.01E-7 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 SUPERFAMILY SSF81665 88 140 3.01E-7 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 SUPERFAMILY SSF56784 335 355 5.02E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05990 c1e203911746b08a4051667653cd9998 648 SUPERFAMILY SSF56784 395 631 5.02E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05990 c1e203911746b08a4051667653cd9998 648 Gene3D G3DSA:3.40.50.1000 458 598 3.2E-27 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05990 c1e203911746b08a4051667653cd9998 648 Gene3D G3DSA:2.70.150.10 27 238 4.2E-27 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 86 635 2.6E-141 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00941 Cadmium-transporting ATPase signature 222 236 3.5E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00941 Cadmium-transporting ATPase signature 121 141 3.5E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00941 Cadmium-transporting ATPase signature 67 79 3.5E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 PRINTS PR00941 Cadmium-transporting ATPase signature 203 219 3.5E-8 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 Pfam PF00122 E1-E2 ATPase 139 316 5.9E-44 T 29-03-2018 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 86 634 1.4E-164 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05990 c1e203911746b08a4051667653cd9998 648 Pfam PF00702 haloacid dehalogenase-like hydrolase 335 544 1.9E-36 T 29-03-2018 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Gene3D G3DSA:1.20.140.10 221 400 1.4E-18 T 29-03-2018 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 388 1.5E-8 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 206 4.2E-18 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 123 2.4E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Gene3D G3DSA:2.40.110.10 122 220 2.1E-26 T 29-03-2018 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 SUPERFAMILY SSF56645 32 245 1.07E-52 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 SUPERFAMILY SSF47203 270 392 2.09E-8 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17780 639cee1d7775d2362bfc87e11b61c03c 411 Gene3D G3DSA:1.10.540.10 1 121 5.9E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 367 63.423 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 28 365 2.6E-95 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 PIRSF PIRSF006004 12 367 8.5E-113 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 Pfam PF04055 Radical SAM superfamily 124 293 2.9E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 Gene3D G3DSA:3.20.20.70 25 366 8.8E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 SMART SM00729 119 340 0.0069 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS08370 9ed3fecde87f99b4bcff6d9e0cf0de66 367 SUPERFAMILY SSF102114 114 337 1.22E-16 T 29-03-2018 MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 1 294 5.6E-75 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 SUPERFAMILY SSF53613 1 286 3.12E-60 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 Pfam PF00294 pfkB family carbohydrate kinase 3 286 3.2E-49 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 PIRSF PIRSF000535 1 300 8.8E-98 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 Gene3D G3DSA:2.20.150.10 3 37 5.0E-8 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain MSG_RS13905 affcd74199331d77b53c6c666dbce662 308 Gene3D G3DSA:3.40.1190.20 38 299 9.4E-39 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 Gene3D G3DSA:3.40.50.720 50 265 1.8E-50 T 29-03-2018 MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 Gene3D G3DSA:3.90.180.10 6 49 2.8E-4 T 29-03-2018 MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 1.9E-54 T 29-03-2018 MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 8.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 8.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 8.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 SUPERFAMILY SSF51735 8 253 1.17E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01125 52e1aefaf884e814d5e8fce14eb85d8a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 5.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15920 d8cbd684b406b59b50260aa2e510c6e3 415 Gene3D G3DSA:3.40.1800.10 285 354 2.2E-6 T 29-03-2018 MSG_RS15920 d8cbd684b406b59b50260aa2e510c6e3 415 SMART SM00507 294 345 5.0E-8 T 29-03-2018 IPR003615 HNH nuclease MSG_RS15920 d8cbd684b406b59b50260aa2e510c6e3 415 Pfam PF01844 HNH endonuclease 311 342 5.7E-5 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MSG_RS15920 d8cbd684b406b59b50260aa2e510c6e3 415 Pfam PF02720 Domain of unknown function (DUF222) 21 303 4.6E-54 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 Gene3D G3DSA:1.10.10.10 4 79 4.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 SUPERFAMILY SSF48008 90 222 5.23E-13 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 SMART SM00345 25 83 7.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 2.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 SMART SM00895 93 215 2.4E-4 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 Gene3D G3DSA:1.20.120.530 80 228 1.1E-15 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 Pfam PF07729 FCD domain 93 204 2.5E-22 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS01705 ce0e7f3b975d2682dd0f17ae8e690b81 231 SUPERFAMILY SSF46785 17 87 7.14E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16385 c9684ef47c6c43daf17aef642ca10055 145 Gene3D G3DSA:1.20.1290.10 52 144 3.2E-12 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16385 c9684ef47c6c43daf17aef642ca10055 145 SUPERFAMILY SSF69118 52 142 4.96E-15 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16385 c9684ef47c6c43daf17aef642ca10055 145 Pfam PF02627 Carboxymuconolactone decarboxylase family 61 140 1.4E-6 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 Pfam PF01180 Dihydroorotate dehydrogenase 50 339 1.2E-100 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 Gene3D G3DSA:3.20.20.70 1 364 4.0E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 SUPERFAMILY SSF51395 2 356 6.41E-96 T 29-03-2018 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 356 4.8E-140 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 293 313 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MSG_RS14945 b6a285d8380c84d0612b52fb7245de56 365 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 337 46.752 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 5 305 2.0E-124 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 PIRSF PIRSF021524 2 311 1.8E-94 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 Pfam PF00583 Acetyltransferase (GNAT) family 39 109 1.9E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 Pfam PF00583 Acetyltransferase (GNAT) family 181 296 1.5E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 Gene3D G3DSA:3.40.630.30 150 310 1.3E-19 T 29-03-2018 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 SUPERFAMILY SSF55729 10 303 2.69E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 Gene3D G3DSA:3.40.630.30 9 143 2.0E-14 T 29-03-2018 MSG_RS21695 8cc8ec1d066ce88726d2f4bef7f0a977 312 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 307 34.816 T 29-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 Gene3D G3DSA:3.40.50.1820 2 280 4.1E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 1.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 1.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 1.4E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 SUPERFAMILY SSF53474 6 279 4.69E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01825 11a1df5b66193d9492a6a8de660ba118 280 Pfam PF12146 Serine aminopeptidase, S33 29 264 7.2E-76 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Pfam PF00384 Molybdopterin oxidoreductase 441 485 6.3E-5 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Pfam PF00384 Molybdopterin oxidoreductase 11 283 9.2E-18 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 SUPERFAMILY SSF53706 176 685 3.53E-198 T 29-03-2018 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 SUPERFAMILY SSF53706 3 146 3.53E-198 T 29-03-2018 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Gene3D G3DSA:2.40.40.20 675 857 3.7E-31 T 29-03-2018 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Gene3D G3DSA:3.40.50.740 310 488 1.9E-19 T 29-03-2018 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Gene3D G3DSA:3.40.228.10 1 309 6.6E-74 T 29-03-2018 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Pfam PF01568 Molydopterin dinucleotide binding domain 730 848 8.9E-12 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 SUPERFAMILY SSF50692 664 694 3.39E-36 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 SUPERFAMILY SSF50692 725 856 3.39E-36 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS00710 43ef456cee1f8645de9fcf4d3cb5cc45 894 Gene3D G3DSA:3.40.228.10 578 674 2.7E-12 T 29-03-2018 MSG_RS06250 0822715aab5c78369282e491304a47b5 344 Pfam PF11350 Protein of unknown function (DUF3152) 130 342 2.1E-102 T 29-03-2018 IPR022603 Domain of unknown function DUF3152 MSG_RS06250 0822715aab5c78369282e491304a47b5 344 SMART SM00235 148 328 5.1E-6 T 29-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 MSG_RS06250 0822715aab5c78369282e491304a47b5 344 SUPERFAMILY SSF55486 126 312 3.39E-17 T 29-03-2018 MSG_RS06250 0822715aab5c78369282e491304a47b5 344 Gene3D G3DSA:3.40.390.10 153 329 3.9E-7 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MSG_RS23560 95176a4b22787c0d009c293fd2acc10e 352 SUPERFAMILY SSF51735 4 148 1.58E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23560 95176a4b22787c0d009c293fd2acc10e 352 Gene3D G3DSA:3.40.50.720 3 128 2.5E-19 T 29-03-2018 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 184 456 4.3E-87 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 Gene3D G3DSA:3.30.360.10 184 465 5.8E-103 T 29-03-2018 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 SUPERFAMILY SSF55347 176 454 4.58E-87 T 29-03-2018 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 Gene3D G3DSA:3.40.50.720 7 183 7.0E-53 T 29-03-2018 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 10 458 3.5E-157 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 189 5.5E-42 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 213 230 5.5E-42 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 231 247 5.5E-42 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 308 334 5.5E-42 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 137 150 5.5E-42 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 458 75.08 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 171 177 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 SUPERFAMILY SSF51735 9 182 2.36E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19410 266b095109500352fe2908af112f5d0d 469 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 179 6.0E-43 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS19410 266b095109500352fe2908af112f5d0d 469 PIRSF PIRSF000110 2 460 6.3E-146 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 ProSitePatterns PS00455 Putative AMP-binding domain signature. 584 595 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:1.10.1200.10 925 1014 1.3E-5 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:3.40.50.980 591 750 6.5E-31 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:3.30.559.10 28 198 3.4E-4 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 SUPERFAMILY SSF51735 1043 1237 1.67E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:3.30.300.30 826 924 6.8E-8 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 SUPERFAMILY SSF56801 474 924 1.7E-57 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:3.40.50.980 466 590 7.8E-9 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Gene3D G3DSA:3.40.50.720 1045 1279 7.1E-7 T 29-03-2018 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Pfam PF00501 AMP-binding enzyme 482 834 3.9E-31 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 Pfam PF07993 Male sterility protein 1123 1252 7.6E-7 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MSG_RS15665 d0eab9f598cbade661f7f760490672c2 1389 SUPERFAMILY SSF52777 211 421 3.34E-7 T 29-03-2018 MSG_RS02280 8c344c4c31041cb85558521977eb799a 333 Gene3D G3DSA:3.40.50.1980 30 166 1.7E-29 T 29-03-2018 MSG_RS02280 8c344c4c31041cb85558521977eb799a 333 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 39 8.5E-5 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MSG_RS02280 8c344c4c31041cb85558521977eb799a 333 SUPERFAMILY SSF53807 44 327 2.63E-38 T 29-03-2018 MSG_RS02280 8c344c4c31041cb85558521977eb799a 333 Gene3D G3DSA:3.40.50.1980 167 331 1.2E-16 T 29-03-2018 MSG_RS02280 8c344c4c31041cb85558521977eb799a 333 Pfam PF01497 Periplasmic binding protein 71 305 2.7E-39 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 8 186 1.4E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 SUPERFAMILY SSF56784 2 221 2.21E-44 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 Gene3D G3DSA:1.10.150.240 22 86 7.3E-17 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 Gene3D G3DSA:3.40.50.1000 87 227 9.0E-25 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 94 189 6.8E-10 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 197 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS21870 9f18c1cf4fde83de753153c86330f308 229 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 201 4.6E-52 T 29-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 Pfam PF03602 Conserved hypothetical protein 95 2 180 6.0E-48 T 29-03-2018 MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 SUPERFAMILY SSF53335 3 178 3.04E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 PIRSF PIRSF004553 1 184 4.5E-62 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 182 1.7E-51 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 Gene3D G3DSA:3.40.50.150 1 183 1.1E-31 T 29-03-2018 MSG_RS07970 d9060edfbf5a6a2238ba388ae178d5c9 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MSG_RS18385 5d61660a4298dd12be528e43ba4652a9 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 233 3.9E-26 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS18385 5d61660a4298dd12be528e43ba4652a9 331 SUPERFAMILY SSF51735 3 326 1.2E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18385 5d61660a4298dd12be528e43ba4652a9 331 Gene3D G3DSA:3.40.50.720 2 331 2.5E-45 T 29-03-2018 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Pfam PF13581 Histidine kinase-like ATPase domain 616 729 6.1E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 SUPERFAMILY SSF81606 409 603 2.88E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 SMART SM00086 178 220 0.0051 T 29-03-2018 IPR001610 PAC motif MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 SUPERFAMILY SSF55874 635 730 1.37E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 10 83 5.1E-17 T 29-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Gene3D G3DSA:3.30.565.10 608 741 4.2E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Gene3D G3DSA:3.60.40.10 372 607 5.6E-28 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Gene3D G3DSA:3.30.450.40 225 371 5.9E-8 T 29-03-2018 IPR029016 GAF domain-like MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 SMART SM00331 391 606 2.2E-27 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 220 9.5E-15 T 29-03-2018 IPR000014 PAS domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 421 606 1.3E-41 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Pfam PF13426 PAS domain 120 219 3.1E-8 T 29-03-2018 IPR000014 PAS domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Gene3D G3DSA:3.30.450.20 92 224 1.8E-19 T 29-03-2018 MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 SUPERFAMILY SSF55785 96 218 1.43E-16 T 29-03-2018 IPR000014 PAS domain MSG_RS23245 b59444e9f069ab93dea14fc8edc078b9 741 Gene3D G3DSA:1.10.1240.30 5 83 9.8E-19 T 29-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 MSG_RS06385 e9272e34ca032c45c1c918a17bb80bcf 360 Gene3D G3DSA:3.40.50.2300 8 130 6.3E-14 T 29-03-2018 MSG_RS06385 e9272e34ca032c45c1c918a17bb80bcf 360 SUPERFAMILY SSF53822 12 346 1.18E-58 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MSG_RS06385 e9272e34ca032c45c1c918a17bb80bcf 360 Pfam PF13458 Periplasmic binding protein 12 343 1.8E-57 T 29-03-2018 IPR028081 Leucine-binding protein domain MSG_RS06385 e9272e34ca032c45c1c918a17bb80bcf 360 Gene3D G3DSA:3.40.50.2300 131 312 1.3E-19 T 29-03-2018 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 SUPERFAMILY SSF54534 82 160 2.49E-11 T 29-03-2018 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 2.2E-45 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 160 8.8E-15 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 PIRSF PIRSF006092 1 163 3.5E-32 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 1.1E-24 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 Gene3D G3DSA:1.10.287.180 6 76 4.9E-25 T 29-03-2018 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 Gene3D G3DSA:3.10.50.30 77 164 3.5E-14 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 SUPERFAMILY SSF46557 7 78 7.72E-23 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MSG_RS19630 3f86a8c50726f2b8305d57016f35d1b2 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 160 28.421 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Gene3D G3DSA:3.40.50.980 225 377 7.8E-35 T 29-03-2018 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 220 231 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Gene3D G3DSA:3.30.300.30 457 558 1.1E-30 T 29-03-2018 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Gene3D G3DSA:3.40.50.980 62 224 2.0E-33 T 29-03-2018 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 SUPERFAMILY SSF56801 66 557 4.19E-127 T 29-03-2018 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 547 3.0E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Pfam PF00501 AMP-binding enzyme 66 463 5.1E-80 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02290 5a9b7cff055ff1e6dd22f7f5394bdef4 559 Gene3D G3DSA:2.30.38.10 378 456 5.1E-14 T 29-03-2018 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PRINTS PR00069 Aldo-keto reductase signature 23 47 3.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PRINTS PR00069 Aldo-keto reductase signature 145 174 3.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PRINTS PR00069 Aldo-keto reductase signature 111 128 3.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PRINTS PR00069 Aldo-keto reductase signature 182 206 3.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PRINTS PR00069 Aldo-keto reductase signature 79 97 3.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 SUPERFAMILY SSF51430 1 255 1.96E-79 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 Pfam PF00248 Aldo/keto reductase family 10 247 5.4E-40 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 Gene3D G3DSA:3.20.20.100 1 262 2.9E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PIRSF PIRSF000097 1 107 4.2E-30 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 PIRSF PIRSF000097 98 260 9.5E-39 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07940 916464be8e244af3ff0a3db00dd70068 262 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 111 128 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS10165 05c282a2deb642e6cacf9534517801e4 462 Pfam PF09084 NMT1/THI5 like 123 272 2.1E-8 T 29-03-2018 IPR015168 SsuA/THI5-like MSG_RS10165 05c282a2deb642e6cacf9534517801e4 462 Gene3D G3DSA:3.40.190.10 157 338 2.3E-22 T 29-03-2018 MSG_RS10165 05c282a2deb642e6cacf9534517801e4 462 SUPERFAMILY SSF53850 69 320 3.7E-28 T 29-03-2018 MSG_RS10165 05c282a2deb642e6cacf9534517801e4 462 Gene3D G3DSA:3.40.190.10 32 156 8.3E-7 T 29-03-2018 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 364 373 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 215 237 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 314 341 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 154 170 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 297 308 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 108 119 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 171 186 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 373 384 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 PRINTS PR00359 B-class P450 signature 342 357 1.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 Pfam PF00067 Cytochrome P450 219 388 3.7E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 Gene3D G3DSA:1.10.630.10 6 424 1.1E-74 T 29-03-2018 MSG_RS16020 905466a5c041a6aaeee67fb893d66adc 424 SUPERFAMILY SSF48264 36 421 1.23E-89 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS04385 8b1ff98c6cd677b47d5ec32b3e2aa8af 78 Pfam PF03621 MbtH-like protein 4 54 1.0E-26 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS04385 8b1ff98c6cd677b47d5ec32b3e2aa8af 78 SUPERFAMILY SSF160582 3 70 1.12E-29 T 29-03-2018 MSG_RS04385 8b1ff98c6cd677b47d5ec32b3e2aa8af 78 SMART SM00923 4 54 1.1E-30 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS04385 8b1ff98c6cd677b47d5ec32b3e2aa8af 78 Gene3D G3DSA:3.90.820.10 3 69 5.4E-33 T 29-03-2018 MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 Gene3D G3DSA:3.40.50.720 1 125 2.4E-33 T 29-03-2018 MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 2.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 154 2.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 Gene3D G3DSA:3.40.50.720 126 201 5.8E-16 T 29-03-2018 MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 SUPERFAMILY SSF51735 1 199 1.43E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 122 150 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 109 125 2.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 173 2.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 154 2.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 2.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 171 0.0028 T 29-03-2018 MSG_RS17715 7553b824a7c1234a82935da6b1802fba 235 Pfam PF00106 short chain dehydrogenase 1 175 7.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 SUPERFAMILY SSF56601 322 675 1.71E-94 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 SUPERFAMILY SSF56519 140 321 1.02E-30 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 Pfam PF00905 Penicillin binding protein transpeptidase domain 348 663 2.6E-87 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 Pfam PF03717 Penicillin-binding Protein dimerisation domain 141 303 3.1E-9 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 Gene3D G3DSA:3.40.710.10 319 673 1.4E-87 T 29-03-2018 MSG_RS15150 ec9a1f13a84a3075d8e52d0e5ffc9fba 688 Gene3D G3DSA:3.90.1310.10 109 318 1.2E-33 T 29-03-2018 MSG_RS01515 25d3252343ba2f1780c14602699e6d4c 516 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 280 1.9E-29 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS01515 25d3252343ba2f1780c14602699e6d4c 516 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 382 465 5.3E-13 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS01515 25d3252343ba2f1780c14602699e6d4c 516 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 101 280 7.4E-23 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS13135 4a6afb13c6b1ed683ea04a34cf3dcfee 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 8 145 9.0E-31 T 29-03-2018 IPR019920 F420-binding domain, putative MSG_RS13135 4a6afb13c6b1ed683ea04a34cf3dcfee 147 Gene3D G3DSA:2.30.110.10 2 146 4.6E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13135 4a6afb13c6b1ed683ea04a34cf3dcfee 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 88 2.5E-9 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS13135 4a6afb13c6b1ed683ea04a34cf3dcfee 147 SUPERFAMILY SSF50475 13 146 1.73E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Pfam PF02910 Fumarate reductase flavoprotein C-term 447 542 1.8E-11 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Gene3D G3DSA:3.50.50.60 5 426 1.7E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SUPERFAMILY SSF51905 362 434 3.45E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SUPERFAMILY SSF51905 7 266 3.45E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SMART SM00567 E-Z type HEAT repeats 638 667 94.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SMART SM00567 E-Z type HEAT repeats 788 818 170.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SMART SM00567 E-Z type HEAT repeats 851 881 19.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SMART SM00567 E-Z type HEAT repeats 820 849 0.45 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SUPERFAMILY SSF48371 623 687 8.64E-30 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SUPERFAMILY SSF48371 720 874 8.64E-30 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Gene3D G3DSA:1.20.58.100 427 529 2.3E-17 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Gene3D G3DSA:1.25.40.70 773 821 6.2E-7 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 SUPERFAMILY SSF46977 432 563 4.32E-33 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 6.2E-12 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 6.2E-12 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Gene3D G3DSA:1.25.10.10 822 895 6.8E-9 T 29-03-2018 IPR011989 Armadillo-like helical MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Pfam PF13646 HEAT repeats 753 830 2.3E-9 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Pfam PF00890 FAD binding domain 14 385 7.6E-39 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 383 3.4E-8 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 3.4E-8 T 29-03-2018 MSG_RS10180 8234673e0590f653e7f0e4343dfa3e36 897 Gene3D G3DSA:1.25.10.10 592 772 3.5E-20 T 29-03-2018 IPR011989 Armadillo-like helical MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Hamap MF_00900 GTPase HflX [hflX]. 76 453 47.661 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Pfam PF16360 GTP-binding GTPase Middle Region 163 249 1.0E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Pfam PF13167 GTP-binding GTPase N-terminal 74 161 2.8E-33 T 29-03-2018 IPR025121 GTPase HflX, N-terminal MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Gene3D G3DSA:3.40.50.300 223 304 3.0E-15 T 29-03-2018 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 57 422 9.4E-130 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Gene3D G3DSA:1.20.120.430 320 440 6.7E-12 T 29-03-2018 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 328 346 1.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 257 277 1.9E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 Pfam PF01926 50S ribosome-binding GTPase 257 383 1.6E-19 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 PIRSF PIRSF006809 48 482 2.9E-164 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MSG_RS08930 86c8adad4be19c8344050b3ac8a39208 482 SUPERFAMILY SSF52540 256 454 6.0E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 PIRSF PIRSF016578 3 380 2.8E-14 T 29-03-2018 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Gene3D G3DSA:1.10.540.10 1 117 8.5E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 3.3E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 SUPERFAMILY SSF56645 2 242 4.32E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 SUPERFAMILY SSF47203 227 380 7.09E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 6.1E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Gene3D G3DSA:1.20.140.10 218 389 2.9E-52 T 29-03-2018 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Gene3D G3DSA:2.40.110.10 119 217 2.4E-35 T 29-03-2018 MSG_RS04745 4151eb72888ad71932218b11d09fb3d2 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 4.7E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01875 1ccb9f0662fdc43030c48a1791c99351 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 5.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01875 1ccb9f0662fdc43030c48a1791c99351 197 SUPERFAMILY SSF46689 4 67 1.28E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01875 1ccb9f0662fdc43030c48a1791c99351 197 Gene3D G3DSA:1.10.357.10 54 186 3.6E-19 T 29-03-2018 MSG_RS01875 1ccb9f0662fdc43030c48a1791c99351 197 Gene3D G3DSA:1.10.10.60 2 53 1.3E-7 T 29-03-2018 MSG_RS01875 1ccb9f0662fdc43030c48a1791c99351 197 SUPERFAMILY SSF48498 74 182 1.56E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 SUPERFAMILY SSF46689 10 73 1.84E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 64 2.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 Gene3D G3DSA:1.10.357.10 68 197 1.4E-19 T 29-03-2018 MSG_RS00820 47afa0c04db7b95f2ef7adb62c70b32f 203 Gene3D G3DSA:1.10.10.60 2 67 1.4E-17 T 29-03-2018 MSG_RS19165 137f94e28021003c084bbd1bb92a9d9e 177 SUPERFAMILY SSF54427 7 171 1.09E-36 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS19165 137f94e28021003c084bbd1bb92a9d9e 177 Pfam PF13577 SnoaL-like domain 12 133 1.2E-24 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS19165 137f94e28021003c084bbd1bb92a9d9e 177 Gene3D G3DSA:3.10.450.50 4 149 3.4E-33 T 29-03-2018 MSG_RS09025 9798a6acdfb0578a5dcd35c7d576ed49 121 SUPERFAMILY SSF56399 2 109 1.21E-27 T 29-03-2018 MSG_RS09025 9798a6acdfb0578a5dcd35c7d576ed49 121 Pfam PF06108 Protein of unknown function (DUF952) 7 98 2.1E-25 T 29-03-2018 IPR009297 Protein of unknown function DUF952 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 SUPERFAMILY SSF46689 261 310 2.87E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 313 358 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 SUPERFAMILY SSF46689 312 360 5.38E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 SMART SM00342 276 362 2.5E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 Gene3D G3DSA:1.10.10.60 259 311 6.6E-11 T 29-03-2018 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 Pfam PF12833 Helix-turn-helix domain 282 361 1.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS06595 d74afd1473b9cff147424ded8eac355c 364 Gene3D G3DSA:1.10.10.60 312 362 1.6E-9 T 29-03-2018 MSG_RS13815 be12b3db5d06052202927fb6dff291f9 309 Pfam PF07859 alpha/beta hydrolase fold 82 279 1.0E-56 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS13815 be12b3db5d06052202927fb6dff291f9 309 Gene3D G3DSA:3.40.50.1820 13 305 4.3E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13815 be12b3db5d06052202927fb6dff291f9 309 SUPERFAMILY SSF53474 49 298 1.11E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 52 63 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:1.10.730.10 537 754 6.3E-66 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 TIGRFAM TIGR00422 valS: valine--tRNA ligase 12 863 2.1E-301 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 SUPERFAMILY SSF46589 820 884 1.36E-13 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 SUPERFAMILY SSF50677 200 344 1.14E-52 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 PRINTS PR00986 Valyl-tRNA synthetase signature 240 257 9.1E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 PRINTS PR00986 Valyl-tRNA synthetase signature 45 56 9.1E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 PRINTS PR00986 Valyl-tRNA synthetase signature 356 369 9.1E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 9.1E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 9.1E-37 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:1.10.287.380 813 882 1.4E-19 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Pfam PF08264 Anticodon-binding domain of tRNA 620 759 1.4E-37 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:3.90.740.10 245 439 2.0E-57 T 29-03-2018 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:3.90.740.10 204 244 5.4E-9 T 29-03-2018 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 24 435 6.6E-149 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 445 577 1.1E-45 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Hamap MF_02004 Valine--tRNA ligase [valS]. 11 885 14.873 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:3.40.50.620 440 536 6.8E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 SUPERFAMILY SSF47323 591 833 1.66E-48 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Gene3D G3DSA:3.40.50.620 25 203 3.8E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 SUPERFAMILY SSF52374 10 201 1.73E-131 T 29-03-2018 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 SUPERFAMILY SSF52374 351 589 1.73E-131 T 29-03-2018 MSG_RS17175 a3ee6d2cc35890b128b11a46208a89ac 885 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 820 884 2.1E-16 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 Gene3D G3DSA:3.40.50.720 1 183 3.0E-35 T 29-03-2018 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 164 1.4E-47 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 324 5.0E-48 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 62 89 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 12 29 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 137 157 1.0E-44 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 SUPERFAMILY SSF48179 183 335 7.65E-47 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 8 326 35.475 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 SUPERFAMILY SSF51735 8 184 2.51E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 Gene3D G3DSA:1.10.1040.10 184 331 1.8E-48 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS03905 6c6cc0cc9e6215b85046bff167e209ec 341 PIRSF PIRSF000114 2 336 1.5E-103 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.8E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 PRINTS PR00315 GTP-binding elongation factor signature 133 142 5.8E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 PRINTS PR00315 GTP-binding elongation factor signature 96 107 5.8E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 PRINTS PR00315 GTP-binding elongation factor signature 80 90 5.8E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 PRINTS PR00315 GTP-binding elongation factor signature 60 68 5.8E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 SUPERFAMILY SSF50447 206 303 9.15E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 7.2E-216 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Gene3D G3DSA:3.40.50.300 2 76 2.4E-11 T 29-03-2018 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 1.6E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 158 3.1E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Gene3D G3DSA:2.40.30.10 302 395 1.3E-30 T 29-03-2018 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 301 394 4.1E-31 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 SUPERFAMILY SSF52540 4 215 2.13E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Gene3D G3DSA:3.40.50.300 77 192 8.6E-32 T 29-03-2018 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Gene3D G3DSA:2.40.30.10 193 300 1.3E-31 T 29-03-2018 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 58.999 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 3.3E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 SUPERFAMILY SSF50465 304 396 1.76E-34 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MSG_RS04295 87d1261e56982b37b5c70ccec67f9b0c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 Gene3D G3DSA:3.40.640.10 69 321 9.4E-74 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 Gene3D G3DSA:3.90.1150.10 322 451 3.2E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 Pfam PF00202 Aminotransferase class-III 23 440 9.3E-95 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 Gene3D G3DSA:3.90.1150.10 1 68 0.02 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 PIRSF PIRSF000521 27 447 5.8E-21 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS04235 ba6dd0488637a61c65c9f28a60d09b9a 451 SUPERFAMILY SSF53383 18 446 2.92E-122 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS08140 2265e58f3f324694461117a2199e093a 579 Gene3D G3DSA:3.40.50.300 260 439 6.1E-9 T 29-03-2018 MSG_RS08140 2265e58f3f324694461117a2199e093a 579 Pfam PF00271 Helicase conserved C-terminal domain 322 375 5.7E-5 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS08140 2265e58f3f324694461117a2199e093a 579 Gene3D G3DSA:3.40.50.300 12 180 3.6E-24 T 29-03-2018 MSG_RS08140 2265e58f3f324694461117a2199e093a 579 SMART SM00487 17 195 1.7E-15 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS08140 2265e58f3f324694461117a2199e093a 579 SUPERFAMILY SSF52540 244 385 1.07E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08140 2265e58f3f324694461117a2199e093a 579 SUPERFAMILY SSF52540 38 175 1.07E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08140 2265e58f3f324694461117a2199e093a 579 Pfam PF04851 Type III restriction enzyme, res subunit 21 173 4.4E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 94 394 1.4E-69 T 29-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 SUPERFAMILY SSF88688 392 490 1.31E-19 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 SUPERFAMILY SSF74650 942 1116 2.73E-6 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Gene3D G3DSA:3.20.110.10 64 321 1.5E-58 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 SMART SM00872 399 470 2.1E-17 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 498 709 2.6E-12 T 29-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1192 1267 6.3E-17 T 29-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Gene3D G3DSA:2.60.40.1180 491 594 4.2E-17 T 29-03-2018 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Gene3D G3DSA:1.20.1270.50 391 490 1.1E-18 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Gene3D G3DSA:2.60.40.10 1181 1289 3.3E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 SUPERFAMILY SSF88713 88 392 2.97E-57 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 SUPERFAMILY SSF74650 485 720 2.98E-34 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MSG_RS04165 de9edc09bc8cfc5bc2563b431ee7f148 1399 Pfam PF09261 Alpha mannosidase middle domain 400 468 5.3E-11 T 29-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MSG_RS11210 ced816cc186900c7b5dd7f01452a3afc 154 Pfam PF00578 AhpC/TSA family 4 127 1.0E-32 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS11210 ced816cc186900c7b5dd7f01452a3afc 154 Gene3D G3DSA:3.40.30.10 1 150 8.4E-37 T 29-03-2018 MSG_RS11210 ced816cc186900c7b5dd7f01452a3afc 154 PIRSF PIRSF000239 1 154 1.6E-20 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS11210 ced816cc186900c7b5dd7f01452a3afc 154 SUPERFAMILY SSF52833 3 150 4.95E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 6.7E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 Gene3D G3DSA:3.40.50.2300 1 125 3.4E-34 T 29-03-2018 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 SUPERFAMILY SSF46894 125 226 2.47E-32 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 SMART SM00862 149 225 4.2E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 SMART SM00448 2 112 7.8E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 Pfam PF00072 Response regulator receiver domain 4 113 1.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 SUPERFAMILY SSF52172 2 119 1.99E-39 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS03475 95e59061348d9b21016b3d77aabef507 227 Gene3D G3DSA:1.10.10.10 126 227 5.3E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 Pfam PF02254 TrkA-N domain 3 118 2.9E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 Pfam PF02080 TrkA-C domain 149 216 4.9E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 Gene3D G3DSA:3.30.70.1450 146 221 1.8E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 Gene3D G3DSA:3.40.50.720 1 145 8.8E-25 T 29-03-2018 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 SUPERFAMILY SSF116726 133 215 3.79E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 SUPERFAMILY SSF51735 1 145 1.61E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 7.1E-10 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 7.1E-10 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 7.1E-10 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 PRINTS PR00335 TrkA potassium uptake protein signature 48 58 7.1E-10 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09090 3706cebeb38eb0035e5654ca633aa99f 224 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 7.1E-10 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 61 278 8.7E-35 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 85 92 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 SUPERFAMILY SSF51306 75 127 1.67E-47 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 SUPERFAMILY SSF51306 158 285 1.67E-47 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 Pfam PF10502 Signal peptidase, peptidase S26 154 249 1.4E-5 T 29-03-2018 IPR019533 Peptidase S26 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 219 238 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 92 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 163 175 1.3E-21 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 Gene3D G3DSA:2.10.109.10 72 292 1.5E-44 T 29-03-2018 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 ProSitePatterns PS00761 Signal peptidases I signature 3. 224 237 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MSG_RS08225 4bbb635f46780aeaa4f2cb5a93c9cd0b 294 Pfam PF00717 Peptidase S24-like 83 127 1.6E-7 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SMART SM00465 17 99 1.1E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 623 2.3E-154 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Pfam PF02151 UvrB/uvrC motif 210 242 4.8E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SUPERFAMILY SSF82771 18 101 4.32E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Gene3D G3DSA:3.40.1440.10 5 102 8.8E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SUPERFAMILY SSF47781 524 643 6.67E-25 T 29-03-2018 IPR010994 RuvA domain 2-like MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 408 576 4.8E-50 T 29-03-2018 IPR001162 UvrC family homology region MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Pfam PF01541 GIY-YIG catalytic domain 18 92 1.8E-11 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SMART SM00278 622 641 1.4 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SMART SM00278 590 609 200.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 641 30.955 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 SUPERFAMILY SSF46600 195 247 6.67E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Gene3D G3DSA:4.10.860.10 186 248 8.4E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Gene3D G3DSA:1.10.150.20 580 643 4.4E-15 T 29-03-2018 MSG_RS10385 b53b336cc6bcc3a2b6ff31bcf4a70096 651 Pfam PF14520 Helix-hairpin-helix domain 591 643 1.3E-9 T 29-03-2018 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 SUPERFAMILY SSF55469 115 167 2.0E-11 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 SUPERFAMILY SSF55469 224 322 2.0E-11 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 Pfam PF00881 Nitroreductase family 203 300 8.2E-6 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 Gene3D G3DSA:3.40.109.10 2 102 3.4E-13 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 SUPERFAMILY SSF55469 5 84 3.8E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14165 d1617b585af2d057a521c5d7a1e3ac28 326 Gene3D G3DSA:3.40.109.10 103 323 2.3E-30 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Gene3D G3DSA:1.10.10.10 249 327 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Gene3D G3DSA:1.10.10.10 3 79 1.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SMART SM00895 349 477 5.8E-10 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SMART SM00895 103 227 9.0E-17 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Gene3D G3DSA:1.20.120.530 90 244 4.7E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SUPERFAMILY SSF48008 348 482 4.18E-14 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Pfam PF07729 FCD domain 349 476 8.4E-14 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Pfam PF07729 FCD domain 103 226 9.7E-18 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SMART SM00345 263 324 0.027 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SMART SM00345 17 78 1.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SUPERFAMILY SSF46785 256 333 8.16E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Gene3D G3DSA:1.20.120.530 332 483 8.4E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 70 3.7E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 259 319 3.9E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SUPERFAMILY SSF48008 102 234 3.92E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS07275 48797e53b07f7ce4908be4354cb11174 483 SUPERFAMILY SSF46785 10 82 8.17E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 Pfam PF01467 Cytidylyltransferase-like 6 131 3.4E-21 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 120 1.0E-4 T 29-03-2018 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.577 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.3E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.3E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.3E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 2.3E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.3E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 SUPERFAMILY SSF52374 4 155 5.36E-45 T 29-03-2018 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 6.8E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 Gene3D G3DSA:3.40.50.620 1 157 1.3E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07975 9e89166209d6131b3e6b9ea4c5eea877 158 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 155 8.2E-60 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 Gene3D G3DSA:3.50.50.60 372 436 3.7E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 Gene3D G3DSA:1.10.405.10 109 194 9.9E-12 T 29-03-2018 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 SUPERFAMILY SSF51905 397 433 2.68E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 SUPERFAMILY SSF51905 1 303 2.68E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 PRINTS PR00757 Flavin-containing amine oxidase signature 415 432 1.8E-9 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 PRINTS PR00757 Flavin-containing amine oxidase signature 366 385 1.8E-9 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 PRINTS PR00757 Flavin-containing amine oxidase signature 4 23 1.8E-9 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 Gene3D G3DSA:3.50.50.60 1 83 2.3E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 Pfam PF01593 Flavin containing amine oxidoreductase 12 433 3.1E-48 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 SUPERFAMILY SSF54373 287 382 1.11E-14 T 29-03-2018 MSG_RS10110 3c737f8431aa43a310a8ee9edf47af36 437 Gene3D G3DSA:3.90.660.10 221 371 1.5E-15 T 29-03-2018 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 SUPERFAMILY SSF52833 11 140 6.9E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 Gene3D G3DSA:1.50.10.10 222 362 3.6E-24 T 29-03-2018 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 Pfam PF03190 Protein of unknown function, DUF255 13 167 8.5E-67 T 29-03-2018 IPR004879 Domain of unknown function DUF255 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 Gene3D G3DSA:3.40.30.10 10 173 8.1E-27 T 29-03-2018 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 PIRSF PIRSF006402 4 670 4.4E-188 T 29-03-2018 IPR024705 Spermatogenesis-associated protein 20 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 SUPERFAMILY SSF48208 197 532 1.19E-65 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS19610 119eb89b12fb9d41d06dd9b2521500b4 672 Gene3D G3DSA:1.50.10.10 363 648 3.5E-28 T 29-03-2018 MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 SUPERFAMILY SSF46785 745 810 1.02E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 Gene3D G3DSA:1.10.10.10 746 800 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 Pfam PF09397 Ftsk gamma domain 749 806 1.3E-23 T 29-03-2018 IPR018541 FtsK gamma domain MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 SMART SM00843 744 809 5.2E-32 T 29-03-2018 IPR018541 FtsK gamma domain MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 Pfam PF01580 FtsK/SpoIIIE family 443 643 1.7E-64 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 Gene3D G3DSA:3.40.50.300 380 683 6.8E-46 T 29-03-2018 MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 116 234 2.6E-6 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region MSG_RS08835 7e3a7b029c58846ce19705c29a30e5a6 835 SUPERFAMILY SSF52540 417 713 4.46E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Gene3D G3DSA:3.30.565.10 397 536 7.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Pfam PF13581 Histidine kinase-like ATPase domain 407 516 6.9E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 SUPERFAMILY SSF55785 18 129 1.07E-5 T 29-03-2018 IPR000014 PAS domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Gene3D G3DSA:3.30.750.24 554 639 2.5E-9 T 29-03-2018 IPR002645 STAS domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 SUPERFAMILY SSF81606 190 393 1.1E-5 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 SUPERFAMILY SSF55874 429 524 2.56E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 200 394 4.5E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Pfam PF13466 STAS domain 558 627 2.6E-10 T 29-03-2018 IPR002645 STAS domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 SMART SM00331 171 394 5.2E-44 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 SUPERFAMILY SSF52091 557 630 7.06E-9 T 29-03-2018 IPR002645 STAS domain MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Gene3D G3DSA:3.30.450.20 15 145 9.1E-16 T 29-03-2018 MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Gene3D G3DSA:3.60.40.10 166 395 4.1E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS17775 0492a5ee28b8d4844dcbb608a319f963 652 Pfam PF08448 PAS fold 22 132 2.1E-9 T 29-03-2018 IPR013656 PAS fold-4 MSG_RS07885 7963c34a58bda279ba5988ecb0257269 64 Gene3D G3DSA:2.30.170.40 2 64 7.7E-21 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS07885 7963c34a58bda279ba5988ecb0257269 64 SUPERFAMILY SSF143800 1 63 1.79E-21 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS07885 7963c34a58bda279ba5988ecb0257269 64 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 5.3E-23 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS07885 7963c34a58bda279ba5988ecb0257269 64 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 64 17.627 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS07885 7963c34a58bda279ba5988ecb0257269 64 Pfam PF00830 Ribosomal L28 family 4 60 2.3E-22 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08335 06dd89ec330c4223af52876aacc0672c 185 Pfam PF09167 Domain of unknown function (DUF1942) 31 154 8.6E-48 T 29-03-2018 IPR015250 MPT63-like GO:0005615 MSG_RS08335 06dd89ec330c4223af52876aacc0672c 185 Gene3D G3DSA:2.60.40.1240 28 156 4.7E-25 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain MSG_RS08335 06dd89ec330c4223af52876aacc0672c 185 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 31 156 9.0E-58 T 29-03-2018 IPR015250 MPT63-like GO:0005615 MSG_RS08335 06dd89ec330c4223af52876aacc0672c 185 SUPERFAMILY SSF81982 29 155 1.83E-48 T 29-03-2018 IPR015250 MPT63-like GO:0005615 MSG_RS03325 4e3f723dbcb6e9b8ef72632e2af2ae6c 182 Pfam PF05610 Protein of unknown function (DUF779) 33 133 1.5E-44 T 29-03-2018 IPR008497 Protein of unknown function DUF779 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 SUPERFAMILY SSF82866 135 333 1.31E-26 T 29-03-2018 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 Pfam PF03176 MMPL family 39 366 8.3E-99 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 Pfam PF03176 MMPL family 616 922 7.7E-82 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 TIGRFAM TIGR00833 actII: transport protein 5 913 1.2E-268 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 Gene3D G3DSA:1.20.1640.10 698 910 7.2E-25 T 29-03-2018 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 Gene3D G3DSA:1.20.1640.10 128 335 2.6E-27 T 29-03-2018 MSG_RS07150 3c3183626c52316d65d266c0311649df 924 SUPERFAMILY SSF82866 685 913 2.35E-30 T 29-03-2018 MSG_RS11655 03d33522c55dfb92682073e66c868e0b 253 Gene3D G3DSA:3.40.50.300 14 250 2.3E-61 T 29-03-2018 MSG_RS11655 03d33522c55dfb92682073e66c868e0b 253 SUPERFAMILY SSF52540 16 233 4.51E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11655 03d33522c55dfb92682073e66c868e0b 253 SMART SM00382 42 226 1.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11655 03d33522c55dfb92682073e66c868e0b 253 Pfam PF00005 ABC transporter 33 170 2.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11655 03d33522c55dfb92682073e66c868e0b 253 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 SUPERFAMILY SSF47203 238 391 3.22E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 SUPERFAMILY SSF56645 3 251 1.83E-67 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Gene3D G3DSA:2.40.110.10 126 225 2.5E-35 T 29-03-2018 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 1.3E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 389 1.9E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Gene3D G3DSA:1.20.140.10 226 394 1.5E-31 T 29-03-2018 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 126 2.0E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21355 8610e3ef56eb640f1207708037a30bec 394 Gene3D G3DSA:1.10.540.10 2 125 7.4E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 SUPERFAMILY SSF56801 28 533 6.8E-150 T 29-03-2018 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Gene3D G3DSA:2.30.38.10 353 432 1.7E-30 T 29-03-2018 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Gene3D G3DSA:3.40.50.980 26 196 1.6E-43 T 29-03-2018 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Pfam PF00501 AMP-binding enzyme 35 439 2.2E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Gene3D G3DSA:3.40.50.980 197 352 4.9E-38 T 29-03-2018 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Gene3D G3DSA:3.30.300.30 434 541 7.7E-26 T 29-03-2018 MSG_RS01710 767eef28fc9cc3e8f3554bae28c6ba4b 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 522 4.2E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 276 443 4.7E-18 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 SUPERFAMILY SSF47928 277 348 3.66E-5 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Gene3D G3DSA:1.10.520.20 277 394 5.6E-13 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Gene3D G3DSA:1.10.520.20 187 276 0.0031 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 PRINTS PR00125 ATP synthase delta subunit signature 404 419 4.6E-8 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 PRINTS PR00125 ATP synthase delta subunit signature 419 437 4.6E-8 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 PRINTS PR00125 ATP synthase delta subunit signature 271 290 4.6E-8 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 135 10.928 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Hamap MF_01416 ATP synthase subunit delta [atpD]. 267 446 14.247 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Pfam PF00430 ATP synthase B/B' CF(0) 3 132 5.2E-19 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 7 154 1.6E-21 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Pfam PF00213 ATP synthase delta (OSCP) subunit 277 443 1.4E-29 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 Gene3D G3DSA:1.20.5.620 59 119 5.5E-10 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS18260 a42def212c44bb31504ab2c4c4bfd66e 446 SUPERFAMILY SSF81573 60 118 1.14E-8 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 Gene3D G3DSA:1.20.58.220 1 108 1.9E-19 T 29-03-2018 MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 6.9E-52 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 Pfam PF01895 PhoU domain 17 103 4.1E-14 T 29-03-2018 IPR026022 PhoU domain MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 Pfam PF01895 PhoU domain 124 204 2.9E-7 T 29-03-2018 IPR026022 PhoU domain MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 SUPERFAMILY SSF109755 2 215 4.5E-50 T 29-03-2018 MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 PIRSF PIRSF003107 1 217 9.3E-47 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MSG_RS05620 1a21d9420c51a95e8c13812ed934bfbe 221 Gene3D G3DSA:1.20.58.220 111 219 2.5E-13 T 29-03-2018 MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 Gene3D G3DSA:3.90.650.10 178 347 2.4E-39 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 SUPERFAMILY SSF55326 23 176 1.79E-29 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 PIRSF PIRSF005644 20 359 6.2E-113 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 Gene3D G3DSA:3.30.1330.10 33 176 2.3E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 SUPERFAMILY SSF56042 180 354 1.94E-42 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 69 172 1.4E-14 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 184 331 6.0E-27 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS11850 9977f663e143d8ac9e5872f4decb4782 359 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 24 359 1.6E-119 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 Pfam PF01545 Cation efflux family 26 212 1.1E-37 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 Gene3D G3DSA:1.20.1510.10 17 212 3.9E-45 T 29-03-2018 MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 SUPERFAMILY SSF161111 20 214 1.57E-45 T 29-03-2018 MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 SUPERFAMILY SSF160240 218 287 3.53E-6 T 29-03-2018 MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 Gene3D G3DSA:3.30.70.1350 215 292 3.2E-10 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MSG_RS02850 9eb14beed1110fc3f38ca07f75b76a7f 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 20 288 3.3E-67 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MSG_RS18520 119c60e49f890c4cdd9b2482b46be97e 383 Pfam PF00149 Calcineurin-like phosphoesterase 1 183 3.5E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MSG_RS18520 119c60e49f890c4cdd9b2482b46be97e 383 PIRSF PIRSF033093 1 383 1.4E-170 T 29-03-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type MSG_RS18520 119c60e49f890c4cdd9b2482b46be97e 383 SUPERFAMILY SSF56300 1 313 2.48E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS18520 119c60e49f890c4cdd9b2482b46be97e 383 Gene3D G3DSA:3.60.21.10 73 256 1.2E-19 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS18520 119c60e49f890c4cdd9b2482b46be97e 383 Gene3D G3DSA:3.60.21.10 1 72 6.8E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS18125 520732641e057c9d053921bed0885752 734 PIRSF PIRSF000463 19 734 1.9E-279 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MSG_RS18125 520732641e057c9d053921bed0885752 734 SMART SM00642 262 621 2.0E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS18125 520732641e057c9d053921bed0885752 734 Gene3D G3DSA:2.60.40.1180 643 734 3.1E-35 T 29-03-2018 MSG_RS18125 520732641e057c9d053921bed0885752 734 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 133 219 2.2E-20 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 MSG_RS18125 520732641e057c9d053921bed0885752 734 Gene3D G3DSA:2.60.40.10 17 115 3.0E-13 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS18125 520732641e057c9d053921bed0885752 734 Gene3D G3DSA:3.20.20.80 248 642 8.0E-78 T 29-03-2018 MSG_RS18125 520732641e057c9d053921bed0885752 734 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 109 734 43.286 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MSG_RS18125 520732641e057c9d053921bed0885752 734 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 636 733 6.8E-22 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MSG_RS18125 520732641e057c9d053921bed0885752 734 SUPERFAMILY SSF81296 150 217 3.29E-10 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS18125 520732641e057c9d053921bed0885752 734 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 117 731 2.8E-268 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 MSG_RS18125 520732641e057c9d053921bed0885752 734 Gene3D G3DSA:2.60.40.10 120 235 1.9E-29 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS18125 520732641e057c9d053921bed0885752 734 SUPERFAMILY SSF51011 631 734 4.17E-34 T 29-03-2018 MSG_RS18125 520732641e057c9d053921bed0885752 734 SUPERFAMILY SSF81296 27 122 1.46E-20 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS18125 520732641e057c9d053921bed0885752 734 SUPERFAMILY SSF51445 193 624 3.57E-111 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS18125 520732641e057c9d053921bed0885752 734 Pfam PF00128 Alpha amylase, catalytic domain 283 351 1.7E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Pfam PF03764 Elongation factor G, domain IV 483 605 1.2E-45 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SUPERFAMILY SSF52540 9 285 4.37E-110 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 3.2E-36 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 698 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SMART SM00889 484 605 4.2E-68 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Pfam PF00679 Elongation factor G C-terminus 607 693 3.9E-30 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Gene3D G3DSA:3.40.50.300 8 277 1.2E-58 T 29-03-2018 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SUPERFAMILY SSF54980 610 696 3.74E-30 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Gene3D G3DSA:3.30.70.870 400 496 2.9E-37 T 29-03-2018 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Gene3D G3DSA:3.30.230.10 497 620 9.4E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Pfam PF14492 Elongation Factor G, domain II 408 482 8.1E-34 T 29-03-2018 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SMART SM00838 607 694 1.8E-58 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SUPERFAMILY SSF54980 406 484 9.71E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Gene3D G3DSA:3.30.70.240 621 698 3.8E-32 T 29-03-2018 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Gene3D G3DSA:2.40.30.10 278 399 1.7E-29 T 29-03-2018 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SUPERFAMILY SSF50447 268 408 1.21E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Hamap MF_00054_B Elongation factor G [fusA]. 9 698 109.526 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Pfam PF00009 Elongation factor Tu GTP binding domain 12 285 1.4E-69 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.9E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.9E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.9E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.9E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 PRINTS PR00315 GTP-binding elongation factor signature 61 69 1.9E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 Pfam PF03144 Elongation factor Tu domain 2 328 394 2.4E-13 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MSG_RS04290 b4336923a5f7de921331b68324d3b54e 701 SUPERFAMILY SSF54211 483 606 1.49E-38 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SUPERFAMILY SSF52540 294 516 3.73E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Gene3D G3DSA:3.40.50.300 293 565 2.6E-63 T 29-03-2018 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SMART SM00382 318 554 4.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 23 90 2.2E-8 T 29-03-2018 IPR032030 YscD, cytoplasmic domain MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Gene3D G3DSA:2.60.200.20 5 104 3.9E-12 T 29-03-2018 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Pfam PF00498 FHA domain 208 270 1.0E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SUPERFAMILY SSF49879 117 172 4.02E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SUPERFAMILY SSF49879 203 277 4.02E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Pfam PF01061 ABC-2 type transporter 569 783 1.1E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Gene3D G3DSA:2.60.200.20 120 286 1.5E-18 T 29-03-2018 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SMART SM00240 25 75 0.14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SMART SM00240 206 256 6.9E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 SUPERFAMILY SSF49879 20 104 1.86E-13 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS05290 1145c0e2ace9bb738c8a273a391515c7 835 Pfam PF00005 ABC transporter 309 456 1.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS19665 1a4f3397d908b7dd29365ec4d706eef0 282 Pfam PF12811 Bax inhibitor 1 like 31 281 8.3E-86 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 MSG_RS19665 1a4f3397d908b7dd29365ec4d706eef0 282 PIRSF PIRSF009160 1 282 1.3E-93 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 SMART SM00278 233 252 0.029 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 SMART SM00278 263 282 48.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 Gene3D G3DSA:1.10.150.310 243 285 2.6E-14 T 29-03-2018 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 Pfam PF10531 SLBB domain 127 180 1.7E-7 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 SUPERFAMILY SSF47781 217 282 6.34E-26 T 29-03-2018 IPR010994 RuvA domain 2-like MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 Gene3D G3DSA:3.10.560.10 115 225 1.8E-8 T 29-03-2018 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 222 283 2.3E-15 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 Gene3D G3DSA:1.10.150.20 226 242 3.5E-5 T 29-03-2018 MSG_RS16965 2a936ebf42090cff16f518b2c9dc20e5 285 Pfam PF12836 Helix-hairpin-helix motif 223 284 3.3E-21 T 29-03-2018 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 1.4E-14 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 123 1.9E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Gene3D G3DSA:1.10.540.10 2 121 2.4E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Gene3D G3DSA:1.20.140.10 223 391 3.0E-30 T 29-03-2018 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 5.5E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 SUPERFAMILY SSF47203 235 390 4.19E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 Gene3D G3DSA:2.40.110.10 122 222 2.8E-34 T 29-03-2018 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS21155 cd8bb07e3215979a49df40dd0236f9d7 391 SUPERFAMILY SSF56645 3 248 9.03E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 SUPERFAMILY SSF52540 351 536 2.66E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 Gene3D G3DSA:1.20.1560.10 2 318 3.9E-20 T 29-03-2018 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 Gene3D G3DSA:3.40.50.300 343 538 5.6E-41 T 29-03-2018 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 SMART SM00382 359 561 5.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 SUPERFAMILY SSF90123 12 323 1.7E-26 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 Pfam PF00005 ABC transporter 352 498 2.8E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11270 47bfc63c9cc9bb52c3beac78ded9873e 566 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 10 534 1.9E-170 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 Gene3D G3DSA:3.30.70.1230 309 502 2.6E-39 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 SMART SM00304 248 300 1.6E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 330 497 1.2E-20 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 SUPERFAMILY SSF55073 325 503 1.05E-45 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 SUPERFAMILY SSF158472 248 297 8.24E-6 T 29-03-2018 MSG_RS19555 53abdd3f5b19808c382987cdfdcdeaef 507 SMART SM00044 296 485 7.8E-15 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 Gene3D G3DSA:3.30.465.10 139 277 3.8E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 Pfam PF08031 Berberine and berberine like 454 487 4.0E-5 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 SUPERFAMILY SSF56176 52 254 3.93E-45 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 Pfam PF01565 FAD binding domain 88 223 8.4E-30 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 Gene3D G3DSA:3.30.43.10 61 138 8.1E-19 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS05320 abc754a42977322a9a10c6553552e6be 494 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 88 121 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MSG_RS20305 18de9395fdeef1cc8a6f3ebb210ff763 664 SUPERFAMILY SSF53300 473 647 1.93E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS20305 18de9395fdeef1cc8a6f3ebb210ff763 664 Gene3D G3DSA:3.40.50.410 466 636 1.3E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS20305 18de9395fdeef1cc8a6f3ebb210ff763 664 SMART SM00327 472 658 6.4E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 252 4.0E-50 T 29-03-2018 MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 199 0.0022 T 29-03-2018 MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 Gene3D G3DSA:3.40.50.720 2 253 5.4E-61 T 29-03-2018 MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 SUPERFAMILY SSF51735 12 252 1.21E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23865 7318be9b4ab6c0b3b9409d2f517dad21 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.6E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 SMART SM00322 59 124 1.3E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 Gene3D G3DSA:3.30.300.20 17 106 6.8E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 SUPERFAMILY SSF54821 106 206 4.05E-36 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.2E-36 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 SUPERFAMILY SSF54814 2 105 2.62E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.004 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 Gene3D G3DSA:3.30.1140.32 107 208 1.8E-35 T 29-03-2018 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 3.0E-94 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MSG_RS04490 7cfaaaa63f98ed3e94f78a47f1fa4c45 280 Pfam PF07650 KH domain 38 109 1.2E-18 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS15890 646242b0ae6a17a8fa82ce035db5ff29 189 Gene3D G3DSA:1.10.357.10 2 187 3.2E-20 T 29-03-2018 MSG_RS15890 646242b0ae6a17a8fa82ce035db5ff29 189 SUPERFAMILY SSF46689 10 71 1.23E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15890 646242b0ae6a17a8fa82ce035db5ff29 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 56 4.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24430 5a1bf5b09e31e7fbe6e8bfcd9a63ece6 321 SUPERFAMILY SSF52540 63 273 1.94E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24430 5a1bf5b09e31e7fbe6e8bfcd9a63ece6 321 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 68 273 8.2E-8 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS24430 5a1bf5b09e31e7fbe6e8bfcd9a63ece6 321 Gene3D G3DSA:3.40.50.300 57 281 1.6E-24 T 29-03-2018 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 Gene3D G3DSA:3.40.50.1390 2 169 5.5E-16 T 29-03-2018 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 Pfam PF00239 Resolvase, N terminal domain 6 153 1.4E-6 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 SMART SM00857 5 158 4.4E-6 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 Gene3D G3DSA:1.20.5.170 418 505 7.9E-4 T 29-03-2018 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 Pfam PF07508 Recombinase 195 317 2.7E-21 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 MSG_RS14975 670e642caf73ef90e8a47da6f8723451 548 SUPERFAMILY SSF53041 4 154 4.58E-8 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Gene3D G3DSA:3.20.20.300 30 317 1.5E-86 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 SUPERFAMILY SSF52279 393 527 1.57E-49 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 SUPERFAMILY SSF52279 555 577 1.57E-49 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 SUPERFAMILY SSF52279 325 352 1.57E-49 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Gene3D G3DSA:3.40.50.1700 318 574 2.3E-74 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Gene3D G3DSA:2.60.40.10 575 685 7.1E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 43 292 1.7E-47 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 325 574 7.0E-56 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 SUPERFAMILY SSF51445 1 324 2.42E-80 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 PRINTS PR00133 Glycosyl hydrolase family 3 signature 72 91 1.3E-27 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 PRINTS PR00133 Glycosyl hydrolase family 3 signature 118 134 1.3E-27 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 PRINTS PR00133 Glycosyl hydrolase family 3 signature 149 165 1.3E-27 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 PRINTS PR00133 Glycosyl hydrolase family 3 signature 43 59 1.3E-27 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 PRINTS PR00133 Glycosyl hydrolase family 3 signature 219 237 1.3E-27 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 Pfam PF14310 Fibronectin type III-like domain 607 670 3.8E-10 T 29-03-2018 IPR026891 Fibronectin type III-like domain MSG_RS01840 e152d5da6d89f94a6ce9d11c19814ef0 689 SMART SM01217 606 671 2.5E-14 T 29-03-2018 IPR026891 Fibronectin type III-like domain MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Gene3D G3DSA:3.60.20.10 2 249 2.1E-63 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Gene3D G3DSA:3.40.50.10490 250 467 2.1E-64 T 29-03-2018 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Pfam PF01380 SIS domain 298 423 4.5E-35 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Pfam PF01380 SIS domain 471 601 2.2E-20 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Gene3D G3DSA:3.40.50.10490 468 620 3.9E-45 T 29-03-2018 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Pfam PF13522 Glutamine amidotransferase domain 68 200 3.0E-20 T 29-03-2018 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 SUPERFAMILY SSF53697 255 622 6.4E-104 T 29-03-2018 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 622 40.625 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 SUPERFAMILY SSF56235 2 239 3.52E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS04945 a548e8c1c36541c3ee00183592c90e02 622 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 622 8.5E-245 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 Gene3D G3DSA:3.40.50.720 6 118 1.1E-29 T 29-03-2018 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 6.5E-45 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 317 6.5E-24 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 Gene3D G3DSA:3.40.50.720 119 289 8.8E-48 T 29-03-2018 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 SUPERFAMILY SSF52283 9 141 1.38E-31 T 29-03-2018 MSG_RS00645 717ea198318c32cc24697f68a8ee3608 322 SUPERFAMILY SSF51735 105 287 2.29E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20825 242d57ec20b281a4dbaa0f8d2c07c734 753 Pfam PF13625 Helicase conserved C-terminal domain 479 596 5.2E-37 T 29-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MSG_RS20825 242d57ec20b281a4dbaa0f8d2c07c734 753 Gene3D G3DSA:1.10.10.10 236 352 0.014 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Gene3D G3DSA:3.40.50.2300 64 185 9.6E-28 T 29-03-2018 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Gene3D G3DSA:3.40.50.2300 186 335 3.2E-34 T 29-03-2018 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 52 8.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 SUPERFAMILY SSF47413 8 66 5.14E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 SUPERFAMILY SSF53822 70 333 2.16E-39 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Gene3D G3DSA:1.10.260.40 24 63 9.5E-15 T 29-03-2018 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Pfam PF13377 Periplasmic binding protein-like domain 181 354 1.3E-19 T 29-03-2018 MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 Gene3D G3DSA:1.10.10.10 5 23 0.053 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22665 acc4cac7fe0e4de0cd0563ea3f041215 359 SMART SM00354 8 79 1.8E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 SUPERFAMILY SSF51556 200 311 7.23E-24 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 SUPERFAMILY SSF51556 339 516 7.23E-24 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 SUPERFAMILY SSF51556 64 123 7.23E-24 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 Gene3D G3DSA:3.20.20.140 193 513 3.7E-37 T 29-03-2018 MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 SUPERFAMILY SSF51338 515 557 5.3E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 SUPERFAMILY SSF51338 6 65 5.3E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 Pfam PF07969 Amidohydrolase family 53 556 2.1E-92 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS14875 1391e78aba5b8c14b003d9e568172143 559 Gene3D G3DSA:2.30.40.10 2 125 1.4E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 SUPERFAMILY SSF52518 35 219 9.26E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 228 363 1.6E-49 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Gene3D G3DSA:3.40.50.1220 235 386 9.6E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Gene3D G3DSA:3.40.50.970 387 599 2.9E-51 T 29-03-2018 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 SUPERFAMILY SSF52467 220 393 5.89E-62 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Gene3D G3DSA:3.40.50.970 33 234 1.6E-57 T 29-03-2018 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 426 579 1.4E-50 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 38 601 8.4E-233 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 SUPERFAMILY SSF52518 403 605 9.11E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 39 204 1.5E-54 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS07760 a054ebbf3e1c6903cf0bf4db4bd40eb3 618 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 463 482 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MSG_RS24160 b6a1ffcffac7ecac1049a3ad977b1e63 524 Gene3D G3DSA:3.90.226.10 4 260 2.5E-60 T 29-03-2018 MSG_RS24160 b6a1ffcffac7ecac1049a3ad977b1e63 524 SUPERFAMILY SSF52096 15 254 2.98E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS24160 b6a1ffcffac7ecac1049a3ad977b1e63 524 SUPERFAMILY SSF52096 230 518 4.42E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS24160 b6a1ffcffac7ecac1049a3ad977b1e63 524 Pfam PF01039 Carboxyl transferase domain 41 522 2.5E-132 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS24160 b6a1ffcffac7ecac1049a3ad977b1e63 524 Gene3D G3DSA:3.90.226.10 261 514 3.8E-67 T 29-03-2018 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 154 44.134 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 SUPERFAMILY SSF53155 3 79 3.73E-19 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 74 153 3.4E-36 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 SUPERFAMILY SSF46767 73 154 1.2E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 Gene3D G3DSA:1.10.10.10 69 156 7.8E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 70 4.8E-12 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 Gene3D G3DSA:3.30.160.70 1 68 1.7E-21 T 29-03-2018 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 75 154 8.0E-35 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS18205 48c82f1b5fea21dc7cd3ac7588655465 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 124 130 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS00685 e4254d61afb8eed4db22638eb999d71a 374 Pfam PF00296 Luciferase-like monooxygenase 13 115 7.4E-24 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00685 e4254d61afb8eed4db22638eb999d71a 374 Pfam PF00296 Luciferase-like monooxygenase 192 342 3.9E-9 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00685 e4254d61afb8eed4db22638eb999d71a 374 Gene3D G3DSA:3.20.20.30 9 373 3.3E-93 T 29-03-2018 MSG_RS00685 e4254d61afb8eed4db22638eb999d71a 374 SUPERFAMILY SSF51679 157 370 2.14E-64 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00685 e4254d61afb8eed4db22638eb999d71a 374 SUPERFAMILY SSF51679 5 115 2.14E-64 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS07855 9ee69df89fc0a64c7fb61b7d2e2dd002 220 Pfam PF01983 Guanylyl transferase CofC like 18 157 2.2E-11 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 MSG_RS07855 9ee69df89fc0a64c7fb61b7d2e2dd002 220 Gene3D G3DSA:3.90.550.10 13 186 7.4E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS07855 9ee69df89fc0a64c7fb61b7d2e2dd002 220 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 16 220 21.654 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 MSG_RS07855 9ee69df89fc0a64c7fb61b7d2e2dd002 220 SUPERFAMILY SSF53448 26 214 6.82E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS07855 9ee69df89fc0a64c7fb61b7d2e2dd002 220 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 18 213 7.7E-58 T 29-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 MSG_RS20895 a2fec882b1f2df04a9cb49f6da58c456 245 Gene3D G3DSA:3.40.50.300 10 236 5.5E-53 T 29-03-2018 MSG_RS20895 a2fec882b1f2df04a9cb49f6da58c456 245 Pfam PF00005 ABC transporter 28 159 1.6E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS20895 a2fec882b1f2df04a9cb49f6da58c456 245 SMART SM00382 37 209 4.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS20895 a2fec882b1f2df04a9cb49f6da58c456 245 SUPERFAMILY SSF52540 15 216 5.32E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20895 a2fec882b1f2df04a9cb49f6da58c456 245 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS09530 493734f78df58b470f54b1406594654e 235 SUPERFAMILY SSF48498 98 213 1.15E-31 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS09530 493734f78df58b470f54b1406594654e 235 Gene3D G3DSA:1.10.357.10 76 217 3.9E-14 T 29-03-2018 MSG_RS09530 493734f78df58b470f54b1406594654e 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 1.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09530 493734f78df58b470f54b1406594654e 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09530 493734f78df58b470f54b1406594654e 235 Gene3D G3DSA:1.10.10.60 2 75 2.1E-17 T 29-03-2018 MSG_RS09530 493734f78df58b470f54b1406594654e 235 SUPERFAMILY SSF46689 25 89 5.99E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS09530 493734f78df58b470f54b1406594654e 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 1.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 211 352 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 158 168 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:3.30.420.10 148 358 6.2E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF00665 Integrase core domain 154 309 6.1E-41 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS19455 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 211 352 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 158 168 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:3.30.420.10 148 358 6.2E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF00665 Integrase core domain 154 309 6.1E-41 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS03710 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 211 352 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF53098 158 168 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 Gene3D G3DSA:3.30.420.10 148 358 6.2E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF00665 Integrase core domain 154 309 6.1E-41 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS01255 e777e3afe9b5e6e74acc900132e85917 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF52151 689 791 4.19E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF52151 496 624 4.19E-71 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF53901 375 396 6.98E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF53901 4 344 6.98E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Pfam PF00550 Phosphopantetheine attachment site 878 944 6.5E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SMART SM00825 Beta-ketoacyl synthase 6 400 7.6E-154 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SMART SM00823 Phosphopantetheine attachment site 876 948 5.5E-27 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF55048 623 688 2.22E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 221 1.8E-56 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 ProSitePatterns PS00012 Phosphopantetheine attachment site. 903 918 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SUPERFAMILY SSF47336 869 954 6.02E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 500 795 3.1E-107 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 353 463 3.9E-19 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 233 348 2.3E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:3.40.47.10 240 398 6.5E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:3.40.366.10 679 800 7.7E-28 T 29-03-2018 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:3.40.47.10 8 237 5.4E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:3.30.70.250 635 678 5.7E-16 T 29-03-2018 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:1.10.1200.10 850 956 5.5E-18 T 29-03-2018 MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Pfam PF00698 Acyl transferase domain 498 812 2.6E-62 T 29-03-2018 IPR014043 Acyl transferase MSG_RS11550 ff4f61fcf366c1892d82a898d2fc02fc 1025 Gene3D G3DSA:3.40.366.10 493 634 3.8E-51 T 29-03-2018 MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 SUPERFAMILY SSF53901 73 368 2.24E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 Gene3D G3DSA:3.40.47.10 225 368 8.0E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 PIRSF PIRSF000451 6 368 8.1E-110 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 233 367 7.1E-20 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 Gene3D G3DSA:3.40.47.10 13 216 2.6E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12240 d2322a8a2c0977cb7e482a469669710f 368 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 84 212 1.2E-17 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 Gene3D G3DSA:3.50.50.60 144 308 8.1E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 Gene3D G3DSA:3.50.50.60 309 654 5.2E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 175 1.9E-7 T 29-03-2018 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 324 342 1.9E-7 T 29-03-2018 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 476 498 1.9E-7 T 29-03-2018 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 SUPERFAMILY SSF51905 155 402 3.18E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 SUPERFAMILY SSF51905 410 630 4.66E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 157 361 6.8E-17 T 29-03-2018 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 177 1.8E-6 T 29-03-2018 MSG_RS22130 04104f748a928d67943f046f49dd7e27 662 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 349 1.8E-6 T 29-03-2018 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 SUPERFAMILY SSF82866 164 360 1.31E-25 T 29-03-2018 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 SUPERFAMILY SSF82866 737 940 8.76E-30 T 29-03-2018 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 Gene3D G3DSA:1.20.1640.10 739 937 9.1E-24 T 29-03-2018 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 Pfam PF03176 MMPL family 64 393 9.3E-108 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 Pfam PF03176 MMPL family 618 949 1.0E-103 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 TIGRFAM TIGR00833 actII: transport protein 30 940 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS13830 1e86addae2716b264c72a05b28129c5f 966 Gene3D G3DSA:1.20.1640.10 151 375 2.0E-25 T 29-03-2018 MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 Pfam PF00355 Rieske [2Fe-2S] domain 465 506 1.8E-7 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 Gene3D G3DSA:3.60.15.10 1 240 3.3E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 Pfam PF13483 Beta-lactamase superfamily domain 2 80 4.1E-6 T 29-03-2018 MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 Gene3D G3DSA:2.102.10.10 463 513 2.9E-9 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 SUPERFAMILY SSF50022 465 512 1.96E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 SUPERFAMILY SSF56281 108 237 3.32E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS24250 afd9de074ab3b98529db8002b5130e8d 516 SUPERFAMILY SSF56281 2 75 3.32E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 3.5E-24 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 3.5E-24 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.5E-24 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 3.5E-24 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 SUPERFAMILY SSF56655 15 258 7.07E-59 T 29-03-2018 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 Gene3D G3DSA:3.40.190.80 141 265 1.3E-25 T 29-03-2018 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 Pfam PF00459 Inositol monophosphatase family 6 255 7.8E-49 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS11180 020f28c5b567f449e0e1fc1451edc3d3 266 Gene3D G3DSA:3.30.540.10 1 139 1.3E-27 T 29-03-2018 MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 2.2E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 Pfam PF02470 MlaD protein 42 111 1.6E-11 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 289 5.1E-77 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01735 833c0b30bc618fdaa9453658597ee8ee 529 Gene3D G3DSA:1.10.287.950 143 300 9.4E-5 T 29-03-2018 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 142 30.525 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 SMART SM00649 11 142 1.2E-84 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 SUPERFAMILY SSF54747 4 74 8.76E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 2.4E-29 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 70 4.0E-13 T 29-03-2018 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 Gene3D G3DSA:3.30.1550.10 5 73 2.2E-35 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 4.2E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 1.5E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 SUPERFAMILY SSF46906 69 142 3.27E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS04110 4ca7e668c6893aef4b4500e357c10487 142 Gene3D G3DSA:1.10.10.250 74 142 6.5E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Pfam PF07885 Ion channel 243 321 2.9E-12 T 29-03-2018 IPR013099 Potassium channel domain MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 SUPERFAMILY SSF51735 337 494 2.36E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Pfam PF02080 TrkA-C domain 503 558 9.0E-7 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 SUPERFAMILY SSF51735 6 128 1.62E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 SUPERFAMILY SSF81324 213 358 3.92E-20 T 29-03-2018 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Pfam PF02254 TrkA-N domain 41 95 3.2E-7 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Pfam PF02254 TrkA-N domain 341 440 7.3E-18 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Gene3D G3DSA:1.10.287.70 211 322 7.9E-12 T 29-03-2018 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Gene3D G3DSA:3.40.50.720 330 468 8.7E-22 T 29-03-2018 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Gene3D G3DSA:3.40.50.720 39 101 2.4E-10 T 29-03-2018 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 SUPERFAMILY SSF116726 499 561 1.57E-6 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS18425 ba17498add01e09b23c7c4a6e6c121d6 581 Gene3D G3DSA:3.30.70.1450 499 571 1.0E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 Gene3D G3DSA:3.30.420.40 8 138 5.7E-21 T 29-03-2018 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 PIRSF PIRSF000538 10 135 4.5E-14 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 PIRSF PIRSF000538 148 454 4.9E-41 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 235 408 5.8E-26 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 SUPERFAMILY SSF53067 12 220 5.96E-24 T 29-03-2018 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 109 4.0E-11 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 Gene3D G3DSA:3.30.420.40 139 220 0.064 T 29-03-2018 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 SUPERFAMILY SSF53067 225 449 3.46E-44 T 29-03-2018 MSG_RS04670 51870f4c896fbc46c51aad7b2404e29d 459 Gene3D G3DSA:3.30.420.40 221 453 2.6E-43 T 29-03-2018 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Pfam PF08029 HisG, C-terminal domain 211 280 3.5E-24 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 4.0E-50 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Gene3D G3DSA:3.30.70.120 213 277 8.7E-25 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 SUPERFAMILY SSF54913 213 284 8.12E-21 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Gene3D G3DSA:3.40.190.10 1 111 9.6E-36 T 29-03-2018 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Gene3D G3DSA:3.40.190.10 112 210 1.0E-19 T 29-03-2018 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Pfam PF01634 ATP phosphoribosyltransferase 49 206 2.3E-39 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 SUPERFAMILY SSF53850 1 209 3.76E-60 T 29-03-2018 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 285 32.221 T 29-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 194 284 1.5E-27 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MSG_RS14810 55d28d3f3341c2aa519fb442bad77941 285 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 SMART SM00829 22 331 3.1E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 Pfam PF00107 Zinc-binding dehydrogenase 160 279 1.2E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 Pfam PF16884 N-terminal domain of oxidoreductase 7 108 5.2E-29 T 29-03-2018 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 Gene3D G3DSA:3.90.180.10 2 149 3.9E-29 T 29-03-2018 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 Gene3D G3DSA:3.40.50.720 150 275 2.0E-27 T 29-03-2018 MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 SUPERFAMILY SSF51735 126 285 4.49E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02495 ba9ceec84b14c602722fc2c3d4483219 342 SUPERFAMILY SSF50129 6 143 1.23E-26 T 29-03-2018 IPR011032 GroES-like MSG_RS07205 a61c8642cdb6b789e71c17b278c3c0dc 107 SUPERFAMILY SSF103481 6 105 5.1E-15 T 29-03-2018 MSG_RS07205 a61c8642cdb6b789e71c17b278c3c0dc 107 Pfam PF00893 Small Multidrug Resistance protein 2 94 1.1E-25 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MSG_RS06365 5d9a046a2027e7567a9e7bda0a864409 155 SUPERFAMILY SSF160904 3 147 5.89E-27 T 29-03-2018 MSG_RS06365 5d9a046a2027e7567a9e7bda0a864409 155 Gene3D G3DSA:1.10.3300.10 1 150 2.0E-26 T 29-03-2018 IPR023286 ABATE domain MSG_RS06365 5d9a046a2027e7567a9e7bda0a864409 155 Pfam PF11706 CGNR zinc finger 104 148 5.1E-17 T 29-03-2018 IPR021005 Zinc finger, CGNR MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 94 108 5.8E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 62 5.8E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 25 33 5.8E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 2 282 2.5E-104 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 Gene3D G3DSA:3.40.50.1820 2 291 1.3E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 PIRSF PIRSF005539 1 289 1.1E-103 T 29-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 Pfam PF00561 alpha/beta hydrolase fold 24 270 9.6E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21505 285b6d92701a2be083cd12dc540e7651 294 SUPERFAMILY SSF53474 5 281 6.73E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24060 fdc7fba692bbb9b382f3f53c6af1a725 238 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 39 234 5.0E-60 T 29-03-2018 MSG_RS24060 fdc7fba692bbb9b382f3f53c6af1a725 238 Gene3D G3DSA:3.90.70.10 59 238 2.7E-14 T 29-03-2018 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SMART SM00271 3 60 6.5E-32 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Pfam PF00684 DnaJ central domain 146 210 4.9E-12 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SUPERFAMILY SSF57938 133 213 1.26E-17 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SUPERFAMILY SSF49493 113 137 8.37E-16 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SUPERFAMILY SSF49493 189 263 8.37E-16 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SUPERFAMILY SSF46565 3 104 3.27E-33 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Gene3D G3DSA:2.60.260.20 208 257 2.1E-9 T 29-03-2018 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Gene3D G3DSA:2.10.230.10 143 207 1.5E-15 T 29-03-2018 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Pfam PF01556 DnaJ C terminal domain 122 337 2.0E-35 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 380 36.444 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 SUPERFAMILY SSF49493 262 348 2.75E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Gene3D G3DSA:2.60.260.20 258 369 1.0E-26 T 29-03-2018 MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Pfam PF00226 DnaJ domain 4 65 1.3E-25 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 PRINTS PR00625 DnaJ domain signature 24 39 4.5E-23 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 PRINTS PR00625 DnaJ domain signature 6 24 4.5E-23 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 PRINTS PR00625 DnaJ domain signature 60 79 4.5E-23 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 PRINTS PR00625 DnaJ domain signature 40 60 4.5E-23 T 29-03-2018 IPR001623 DnaJ domain MSG_RS16725 4b89f72951da4006abf11b4abd63ebe5 384 Gene3D G3DSA:1.10.287.110 1 108 1.6E-31 T 29-03-2018 IPR001623 DnaJ domain MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 73 83 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 SMART SM00870 3 305 6.2E-90 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 Gene3D G3DSA:3.40.50.40 196 306 1.2E-24 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 2.0E-15 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 PRINTS PR00139 Asparaginase/glutaminase family signature 243 261 2.0E-15 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 PRINTS PR00139 Asparaginase/glutaminase family signature 72 90 2.0E-15 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 Pfam PF00710 Asparaginase, N-terminal 4 164 4.4E-41 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 Gene3D G3DSA:3.40.50.1170 1 173 1.9E-40 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 PIRSF PIRSF500176 1 309 1.2E-81 T 29-03-2018 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 PIRSF PIRSF001220 1 308 6.0E-78 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 SUPERFAMILY SSF53774 1 307 1.96E-74 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MSG_RS10950 5974dd5c5d882a898c27071a8e69a809 309 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MSG_RS01035 5aea3f5809b16bb82bc678a86871adb2 363 Pfam PF00501 AMP-binding enzyme 196 313 1.4E-6 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS01035 5aea3f5809b16bb82bc678a86871adb2 363 SUPERFAMILY SSF56801 52 313 1.7E-18 T 29-03-2018 MSG_RS01035 5aea3f5809b16bb82bc678a86871adb2 363 Gene3D G3DSA:3.40.50.980 93 277 8.3E-13 T 29-03-2018 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 Pfam PF11838 ERAP1-like C-terminal domain 535 854 2.6E-57 T 29-03-2018 IPR024571 ERAP1-like C-terminal domain MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 Gene3D G3DSA:2.60.40.1730 6 202 4.1E-36 T 29-03-2018 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 SUPERFAMILY SSF55486 212 458 8.5E-77 T 29-03-2018 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 Pfam PF01433 Peptidase family M1 domain 216 449 1.4E-60 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 277 7.3E-25 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 7.3E-25 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 7.3E-25 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 7.3E-25 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 7.3E-25 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 SUPERFAMILY SSF63737 6 201 2.09E-42 T 29-03-2018 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 Gene3D G3DSA:1.10.390.10 287 453 1.3E-49 T 29-03-2018 MSG_RS17265 0a16b3a1f367fdf9efa466df0b17aa67 866 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 860 7.5E-302 T 29-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 MSG_RS09590 6b58ff75a41d23d0a0bd69b9e896862b 316 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 13 302 1.5E-89 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MSG_RS05495 d80d717fad1766c74ab283bebdab642f 362 Pfam PF00962 Adenosine/AMP deaminase 13 351 2.6E-103 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MSG_RS05495 d80d717fad1766c74ab283bebdab642f 362 Gene3D G3DSA:3.20.20.140 6 353 2.5E-80 T 29-03-2018 MSG_RS05495 d80d717fad1766c74ab283bebdab642f 362 SUPERFAMILY SSF51556 10 345 5.84E-72 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS05495 d80d717fad1766c74ab283bebdab642f 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 7.4E-74 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MSG_RS05495 d80d717fad1766c74ab283bebdab642f 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 55.723 T 29-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 213 361 3.9E-13 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 50 363 2.9E-40 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 177 194 - T 29-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 44 201 2.0E-43 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 SUPERFAMILY SSF54197 44 202 6.34E-50 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 SUPERFAMILY SSF54197 205 363 5.27E-33 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 Gene3D G3DSA:3.30.428.10 70 191 1.1E-38 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 PIRSF PIRSF000808 39 364 3.8E-112 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MSG_RS03990 63f7c7cd2e182a8cf7b8e0335692de41 364 Gene3D G3DSA:3.30.428.10 192 364 3.9E-26 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 SUPERFAMILY SSF51905 1 338 7.94E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 Gene3D G3DSA:3.50.50.60 4 147 2.4E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.3E-12 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 3.3E-12 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 3.3E-12 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.3E-12 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 Gene3D G3DSA:3.40.50.720 154 454 1.4E-28 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 329 2.6E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.3E-7 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 2.3E-7 T 29-03-2018 MSG_RS02890 2458993a0feb4a5388133f1a74a68f76 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 2.3E-7 T 29-03-2018 MSG_RS03540 490e7852a79dd3ce9a4453222c00e01c 363 PIRSF PIRSF016753 52 363 4.9E-120 T 29-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted MSG_RS03540 490e7852a79dd3ce9a4453222c00e01c 363 Gene3D G3DSA:3.40.1130.10 105 359 3.5E-29 T 29-03-2018 MSG_RS03540 490e7852a79dd3ce9a4453222c00e01c 363 SMART SM00563 149 268 3.3E-22 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS03540 490e7852a79dd3ce9a4453222c00e01c 363 Pfam PF01553 Acyltransferase 134 265 1.1E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS03540 490e7852a79dd3ce9a4453222c00e01c 363 SUPERFAMILY SSF69593 106 356 2.22E-44 T 29-03-2018 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 SUPERFAMILY SSF52440 1 110 1.44E-40 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 106 5.0E-39 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 SUPERFAMILY SSF51230 585 653 1.2E-20 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Pfam PF00364 Biotin-requiring enzyme 589 652 7.3E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Gene3D G3DSA:3.40.50.20 1 120 6.7E-47 T 29-03-2018 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Gene3D G3DSA:3.30.1490.20 121 197 6.0E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Gene3D G3DSA:3.30.470.20 198 451 1.8E-92 T 29-03-2018 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 SUPERFAMILY SSF51246 322 445 3.03E-31 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 113 315 1.9E-59 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Gene3D G3DSA:2.40.50.100 578 655 3.4E-18 T 29-03-2018 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 610 627 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 SMART SM00878 327 443 4.2E-43 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 SUPERFAMILY SSF56059 80 319 6.36E-56 T 29-03-2018 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 Pfam PF02785 Biotin carboxylase C-terminal domain 327 443 1.2E-28 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS20265 edb787c786d1d39da770d2a98c93ae1a 662 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 279 286 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS00435 58503b02638d951e151a16069e934152 222 SUPERFAMILY SSF51679 20 204 5.23E-22 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00435 58503b02638d951e151a16069e934152 222 Pfam PF00296 Luciferase-like monooxygenase 24 189 3.6E-17 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00435 58503b02638d951e151a16069e934152 222 Gene3D G3DSA:3.20.20.30 1 220 1.9E-23 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 210 747 2.9E-107 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 ProSitePatterns PS01229 Hypothetical cof family signature 2. 644 666 - T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Gene3D G3DSA:3.30.70.100 3 87 1.0E-18 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Pfam PF00403 Heavy-metal-associated domain 16 74 8.0E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Gene3D G3DSA:3.40.1110.10 465 571 6.0E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 451 457 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00943 Copper-transporting ATPase signature 432 447 2.1E-5 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00943 Copper-transporting ATPase signature 145 164 2.1E-5 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00943 Copper-transporting ATPase signature 372 386 2.1E-5 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00943 Copper-transporting ATPase signature 678 692 2.1E-5 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00943 Copper-transporting ATPase signature 621 638 2.1E-5 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Gene3D G3DSA:3.40.50.1000 572 708 2.6E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF56784 447 467 1.05E-56 T 29-03-2018 IPR023214 HAD-like domain MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF56784 506 744 1.05E-56 T 29-03-2018 IPR023214 HAD-like domain MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF81653 259 349 5.23E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Gene3D G3DSA:1.20.1110.10 201 464 4.4E-46 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Pfam PF00702 haloacid dehalogenase-like hydrolase 445 658 1.9E-41 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 747 1.9E-149 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 Pfam PF00122 E1-E2 ATPase 261 428 3.5E-49 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF81665 350 443 1.44E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF81665 206 242 1.44E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF81665 693 723 1.44E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 ProSitePatterns PS01047 Heavy-metal-associated domain. 18 46 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 SUPERFAMILY SSF55008 10 77 1.24E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 217 724 4.9E-83 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 569 580 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 449 463 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 601 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 679 7.4E-24 T 29-03-2018 MSG_RS00900 68b584521f267aa5e54c749207141c97 759 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 160 746 5.0E-170 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 Gene3D G3DSA:3.40.50.720 1 254 2.7E-51 T 29-03-2018 MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.3E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 Pfam PF00106 short chain dehydrogenase 6 202 1.9E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 SUPERFAMILY SSF51735 5 251 1.7E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07255 63195aad3bab8fca1eafc9fa101fc6e2 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:3.40.50.300 427 612 3.3E-38 T 29-03-2018 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 SUPERFAMILY SSF50447 610 693 8.52E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 SUPERFAMILY SSF52540 429 599 2.76E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:2.40.30.10 838 936 1.6E-25 T 29-03-2018 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 935 16.67 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 ProSitePatterns PS01176 Initiation factor 2 signature. 889 911 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:3.30.56.50 352 392 0.0014 T 29-03-2018 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:3.30.56.50 6 47 3.9E-12 T 29-03-2018 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:3.40.50.10050 740 816 2.2E-24 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Pfam PF00009 Elongation factor Tu GTP binding domain 437 597 2.2E-31 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 SUPERFAMILY SSF52156 717 844 8.5E-36 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 SUPERFAMILY SSF50447 838 935 8.73E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 344 936 5.0E-223 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 52 1.0E-14 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 352 397 1.3E-6 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 PRINTS PR00315 GTP-binding elongation factor signature 504 515 7.2E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 PRINTS PR00315 GTP-binding elongation factor signature 436 449 7.2E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 PRINTS PR00315 GTP-binding elongation factor signature 488 498 7.2E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 PRINTS PR00315 GTP-binding elongation factor signature 540 549 7.2E-10 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 434 593 8.4E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Pfam PF11987 Translation-initiation factor 2 725 827 5.1E-33 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MSG_RS08535 587a9304ea68a105d707a1e4135b89aa 936 Gene3D G3DSA:2.40.30.10 613 739 6.2E-35 T 29-03-2018 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 331 3.9E-126 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 Gene3D G3DSA:3.20.20.70 7 253 1.7E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 PIRSF PIRSF006621 1 341 3.3E-119 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 Pfam PF01207 Dihydrouridine synthase (Dus) 13 322 9.4E-111 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 Gene3D G3DSA:1.10.1200.80 264 331 1.7E-18 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MSG_RS21660 a1bfaa5a9474a4484d1e469dad047488 377 SUPERFAMILY SSF51395 11 328 9.34E-77 T 29-03-2018 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 4 17 5.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 48 5.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 50 4.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 SUPERFAMILY SSF46689 2 57 2.84E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 Gene3D G3DSA:1.10.10.60 1 61 1.0E-16 T 29-03-2018 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 SUPERFAMILY SSF48498 69 203 5.89E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 Gene3D G3DSA:1.10.357.10 67 205 5.9E-24 T 29-03-2018 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 69 202 5.6E-14 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 PRINTS PR00400 Tetracycline repressor protein signature 126 145 1.5E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 PRINTS PR00400 Tetracycline repressor protein signature 16 39 1.5E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MSG_RS00915 301ce23d7cff500309b8533b3d9ac70f 206 PRINTS PR00400 Tetracycline repressor protein signature 185 199 1.5E-6 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Gene3D G3DSA:3.50.40.10 208 405 3.5E-63 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Pfam PF03483 B3/4 domain 224 395 1.6E-56 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 827 38.373 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SMART SM00873 222 395 2.2E-71 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 833 2.9E-161 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Gene3D G3DSA:3.30.56.10 1 197 1.9E-39 T 29-03-2018 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Pfam PF01588 Putative tRNA binding domain 50 147 2.0E-17 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Pfam PF03484 tRNA synthetase B5 domain 422 487 1.0E-14 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Pfam PF03147 Ferredoxin-fold anticodon binding domain 740 833 4.5E-24 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SMART SM00896 740 833 1.6E-41 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF50249 48 197 3.14E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF56037 210 404 2.62E-59 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SMART SM00874 419 487 4.1E-19 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Gene3D G3DSA:3.30.70.380 737 833 4.2E-25 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF55681 483 599 6.46E-35 T 29-03-2018 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF55681 629 729 6.46E-35 T 29-03-2018 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF54991 738 833 7.59E-26 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Gene3D G3DSA:3.30.930.10 503 729 4.4E-32 T 29-03-2018 MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 SUPERFAMILY SSF46955 422 491 1.37E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS11490 ff8e6e6797329f2a1b5af53aa625f312 834 Gene3D G3DSA:3.30.56.10 418 491 1.6E-17 T 29-03-2018 MSG_RS23580 bfbc801474bfd503527768d9611c27e5 236 SMART SM01110 39 236 1.3E-94 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS23580 bfbc801474bfd503527768d9611c27e5 236 Gene3D G3DSA:3.40.50.1820 40 236 3.7E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS23580 bfbc801474bfd503527768d9611c27e5 236 SUPERFAMILY SSF53474 40 235 9.53E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS23580 bfbc801474bfd503527768d9611c27e5 236 Pfam PF01083 Cutinase 41 236 7.8E-45 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Gene3D G3DSA:1.10.3060.10 570 731 2.7E-24 T 29-03-2018 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Pfam PF07516 SecA Wing and Scaffold domain 635 718 7.1E-14 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Pfam PF01043 SecA preprotein cross-linking domain 247 347 2.2E-21 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Gene3D G3DSA:3.40.50.300 76 242 2.3E-10 T 29-03-2018 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SUPERFAMILY SSF81886 584 738 3.53E-31 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 ProSitePatterns PS01312 SecA family signature. 489 504 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 13 774 0.0 T 29-03-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Gene3D G3DSA:3.40.50.300 406 505 8.5E-20 T 29-03-2018 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Gene3D G3DSA:3.40.50.300 507 569 2.2E-13 T 29-03-2018 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Pfam PF07517 SecA DEAD-like domain 18 389 4.4E-82 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Hamap MF_01382 Protein translocase subunit SecA [secA]. 15 732 15.295 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 108 122 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 124 134 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 402 415 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 70 94 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 328 350 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 177 197 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 PRINTS PR00906 SecA protein signature 365 382 7.5E-41 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SMART SM00957 16 391 9.8E-143 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SUPERFAMILY SSF52540 357 404 3.29E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SUPERFAMILY SSF52540 18 235 3.29E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SUPERFAMILY SSF81767 244 355 4.32E-30 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SMART SM00958 234 347 9.3E-26 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 Gene3D G3DSA:3.90.1440.10 243 357 4.9E-28 T 29-03-2018 MSG_RS12795 888f4eb10f44a2881d9811f4396d43ae 774 SUPERFAMILY SSF52540 406 566 1.33E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.2E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 Gene3D G3DSA:3.40.50.720 10 253 3.8E-51 T 29-03-2018 MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 Pfam PF00106 short chain dehydrogenase 11 193 4.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 PIRSF PIRSF000126 5 267 5.1E-61 T 29-03-2018 MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 SUPERFAMILY SSF51735 8 259 8.22E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01015 02d12d95ef001a228b09bb32f0ee3328 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS19020 f575fdd11ac22d18b821f18e7f255d2c 304 PIRSF PIRSF002936 3 304 8.0E-130 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS19020 f575fdd11ac22d18b821f18e7f255d2c 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 12 304 3.1E-129 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS19020 f575fdd11ac22d18b821f18e7f255d2c 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 33 257 1.2E-42 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MSG_RS19020 f575fdd11ac22d18b821f18e7f255d2c 304 Gene3D G3DSA:3.40.50.620 5 271 1.3E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS19020 f575fdd11ac22d18b821f18e7f255d2c 304 SUPERFAMILY SSF52402 9 212 2.15E-60 T 29-03-2018 MSG_RS13505 9d443d8a6c704c3ed1f70ecc704f95c5 435 Gene3D G3DSA:3.40.50.1970 22 200 2.7E-42 T 29-03-2018 MSG_RS13505 9d443d8a6c704c3ed1f70ecc704f95c5 435 Gene3D G3DSA:1.20.1090.10 201 435 1.1E-53 T 29-03-2018 MSG_RS13505 9d443d8a6c704c3ed1f70ecc704f95c5 435 Pfam PF00465 Iron-containing alcohol dehydrogenase 22 421 5.5E-100 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MSG_RS13505 9d443d8a6c704c3ed1f70ecc704f95c5 435 SUPERFAMILY SSF56796 22 431 1.24E-93 T 29-03-2018 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 SUPERFAMILY SSF54980 410 505 1.68E-22 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 SMART SM00838 409 493 0.002 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 186 2.0E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Gene3D G3DSA:3.30.70.240 404 560 3.2E-26 T 29-03-2018 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Hamap MF_00071 Elongation factor 4 [lepA]. 1 609 283.039 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 SUPERFAMILY SSF54980 303 382 6.12E-19 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 SUPERFAMILY SSF52540 10 214 9.27E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Pfam PF00009 Elongation factor Tu GTP binding domain 16 193 3.3E-50 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Gene3D G3DSA:2.40.30.10 200 299 2.3E-19 T 29-03-2018 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 SUPERFAMILY SSF50447 177 295 2.52E-23 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Gene3D G3DSA:3.30.70.870 300 379 3.4E-27 T 29-03-2018 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.5E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.5E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.5E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.5E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 PRINTS PR00315 GTP-binding elongation factor signature 19 32 3.5E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Pfam PF00679 Elongation factor G C-terminus 410 496 9.0E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Pfam PF06421 GTP-binding protein LepA C-terminus 500 604 3.7E-48 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 Gene3D G3DSA:3.40.50.300 9 197 6.9E-35 T 29-03-2018 MSG_RS16915 62d2aa8efe24fe6ce89a379670dbabc2 615 TIGRFAM TIGR01393 lepA: elongation factor 4 16 607 1.1E-296 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SMART SM00823 Phosphopantetheine attachment site 1260 1315 4.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SMART SM00823 Phosphopantetheine attachment site 37 108 7.6E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF52151 926 1022 7.59E-45 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF52151 733 857 7.59E-45 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.190.10 1332 1449 0.047 T 29-03-2018 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 507 565 5.4E-11 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SMART SM00825 Beta-ketoacyl synthase 132 557 2.8E-186 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:1.10.1200.10 1248 1331 2.9E-15 T 29-03-2018 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:1.10.1200.10 21 110 1.9E-12 T 29-03-2018 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF47336 30 143 5.23E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF55048 865 921 8.24E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF47336 1257 1335 7.98E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 387 504 1.7E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF00550 Phosphopantetheine attachment site 38 104 2.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF00550 Phosphopantetheine attachment site 1266 1308 1.5E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.366.10 732 1053 4.0E-53 T 29-03-2018 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF00975 Thioesterase domain 1530 1631 1.4E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.190.10 607 690 0.012 T 29-03-2018 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.47.10 394 555 7.5E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF53901 532 553 1.22E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF53901 131 497 1.22E-91 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF00698 Acyl transferase domain 733 1054 8.4E-56 T 29-03-2018 IPR014043 Acyl transferase MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 735 1039 6.9E-77 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.50.1820 1514 1780 1.4E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 SUPERFAMILY SSF53474 1523 1779 2.16E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Gene3D G3DSA:3.40.47.10 126 391 7.7E-81 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS24165 03d8ffe849f4e0f8baa425f201acfaa1 1795 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 131 379 3.7E-82 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 SUPERFAMILY SSF50677 329 515 1.31E-43 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 305 506 1.9E-55 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 232 972 1.7E-212 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Gene3D G3DSA:3.40.50.620 504 769 1.1E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Gene3D G3DSA:3.40.50.620 27 318 1.5E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 SUPERFAMILY SSF52374 35 184 2.25E-102 T 29-03-2018 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 SUPERFAMILY SSF52374 518 789 2.25E-102 T 29-03-2018 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 SUPERFAMILY SSF52374 232 310 2.25E-102 T 29-03-2018 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 SUPERFAMILY SSF47323 784 972 1.68E-31 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 29 972 21.373 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Gene3D G3DSA:3.90.740.10 319 503 1.2E-46 T 29-03-2018 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Pfam PF08264 Anticodon-binding domain of tRNA 819 934 1.2E-12 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Pfam PF09334 tRNA synthetases class I (M) 76 182 6.1E-13 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 237 253 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 299 318 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 602 620 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 654 676 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 687 697 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 164 181 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 PRINTS PR00985 Leucyl-tRNA synthetase signature 270 283 1.5E-53 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 80 90 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS00275 fb722579d956ec936be91724f0dfa89f 972 Gene3D G3DSA:1.10.730.10 770 909 9.6E-24 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS16960 925f3af322be09cd6a0d170f9adedbe2 512 Pfam PF03772 Competence protein 223 486 1.3E-48 T 29-03-2018 IPR004477 ComEC/Rec2-related protein MSG_RS16960 925f3af322be09cd6a0d170f9adedbe2 512 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 245 411 4.8E-13 T 29-03-2018 IPR004477 ComEC/Rec2-related protein MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 Gene3D G3DSA:2.102.10.10 44 160 1.5E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 Pfam PF00355 Rieske [2Fe-2S] domain 47 140 1.3E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 SUPERFAMILY SSF55961 171 418 1.49E-37 T 29-03-2018 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 154 180 8.9E-10 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 8.9E-10 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 190 416 2.3E-37 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 SUPERFAMILY SSF50022 12 169 4.98E-41 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21310 c8b877f1ef1bd7ccb3ec0dfdbb9b2850 426 Gene3D G3DSA:3.90.380.10 161 424 5.4E-60 T 29-03-2018 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 SUPERFAMILY SSF56425 342 499 1.2E-33 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 SUPERFAMILY SSF51905 217 333 4.33E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 SUPERFAMILY SSF51905 2 124 4.33E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 SUPERFAMILY SSF51905 498 556 4.33E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 Gene3D G3DSA:3.50.50.60 4 413 1.5E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 Gene3D G3DSA:3.50.50.60 414 556 1.5E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12530 e0d73fe75db25c1f4fc9ee88f6ccc9eb 565 Pfam PF00890 FAD binding domain 10 540 1.4E-74 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS00990 402aee9409db23b28d4d5d24c178713e 200 SUPERFAMILY SSF54637 7 196 2.16E-41 T 29-03-2018 IPR029069 HotDog domain MSG_RS00990 402aee9409db23b28d4d5d24c178713e 200 Gene3D G3DSA:3.10.129.10 38 200 7.0E-24 T 29-03-2018 MSG_RS00990 402aee9409db23b28d4d5d24c178713e 200 Pfam PF03061 Thioesterase superfamily 117 188 1.2E-8 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 Pfam PF07972 NrdI Flavodoxin like 7 128 5.1E-45 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 Hamap MF_00128 Protein NrdI [nrdI]. 5 138 35.091 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 PIRSF PIRSF005087 3 142 1.3E-53 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 SUPERFAMILY SSF52218 4 138 1.68E-22 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 Gene3D G3DSA:3.40.50.360 6 137 1.1E-24 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS07345 2d275e927d6ea7f412acfd322fa23213 149 TIGRFAM TIGR00333 nrdI: nrdI protein 7 136 2.8E-47 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MSG_RS10885 53802ec3325427f348bb9d8b7cf3a724 76 Pfam PF03621 MbtH-like protein 4 54 1.3E-27 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS10885 53802ec3325427f348bb9d8b7cf3a724 76 Gene3D G3DSA:3.90.820.10 3 69 1.6E-32 T 29-03-2018 MSG_RS10885 53802ec3325427f348bb9d8b7cf3a724 76 SMART SM00923 4 54 3.4E-31 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS10885 53802ec3325427f348bb9d8b7cf3a724 76 SUPERFAMILY SSF160582 3 69 5.36E-29 T 29-03-2018 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 Pfam PF08281 Sigma-70, region 4 115 164 1.1E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 170 3.0E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 SUPERFAMILY SSF88659 103 171 8.22E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 SUPERFAMILY SSF88946 2 74 6.67E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 Gene3D G3DSA:1.10.10.10 64 173 4.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 Gene3D G3DSA:1.10.1740.10 1 63 1.4E-15 T 29-03-2018 MSG_RS14335 f1f061fdef213d21ae776b0ca6323f32 176 Pfam PF04542 Sigma-70 region 2 3 60 5.8E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 Gene3D G3DSA:1.10.10.10 13 82 1.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 Gene3D G3DSA:1.20.120.530 93 232 2.4E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 SMART SM00895 100 221 1.1E-20 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 SMART SM00345 21 80 4.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 SUPERFAMILY SSF48008 100 225 4.71E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 SUPERFAMILY SSF46785 16 84 2.59E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 7.9E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 7.9E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS20835 88d9825aa716a059c624b5d34ea22eab 235 Pfam PF07729 FCD domain 100 220 1.6E-21 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS22365 e0a02d860cd96d811abefa18d96d64ef 270 Gene3D G3DSA:3.90.226.10 11 227 3.0E-62 T 29-03-2018 MSG_RS22365 e0a02d860cd96d811abefa18d96d64ef 270 Gene3D G3DSA:1.10.12.10 228 270 4.4E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS22365 e0a02d860cd96d811abefa18d96d64ef 270 SUPERFAMILY SSF52096 14 269 3.13E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS22365 e0a02d860cd96d811abefa18d96d64ef 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 269 2.8E-56 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS21920 68ac38aff65592606792e5d878773c29 212 Gene3D G3DSA:3.60.15.10 2 196 2.1E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS21920 68ac38aff65592606792e5d878773c29 212 SMART SM00849 7 177 3.7E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS21920 68ac38aff65592606792e5d878773c29 212 Pfam PF13483 Beta-lactamase superfamily domain 2 177 7.6E-20 T 29-03-2018 MSG_RS21920 68ac38aff65592606792e5d878773c29 212 SUPERFAMILY SSF56281 1 189 3.54E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20210 42091a8f214752ad65e7c91ea974a3c0 226 Gene3D G3DSA:3.90.1210.10 52 117 2.0E-12 T 29-03-2018 MSG_RS20210 42091a8f214752ad65e7c91ea974a3c0 226 Pfam PF08666 SAF domain 55 111 1.5E-7 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MSG_RS20210 42091a8f214752ad65e7c91ea974a3c0 226 SMART SM00858 54 116 2.9E-7 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 Gene3D G3DSA:1.10.630.10 2 394 5.8E-75 T 29-03-2018 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 Pfam PF00067 Cytochrome P450 189 367 3.9E-23 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00385 P450 superfamily signature 345 356 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00385 P450 superfamily signature 269 280 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00385 P450 superfamily signature 336 345 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00385 P450 superfamily signature 234 251 2.6E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 SUPERFAMILY SSF48264 12 393 3.14E-97 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 286 313 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 149 164 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 345 356 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 188 210 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 269 280 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 86 97 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 336 345 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18940 422d1c3c5d4962695747795fd3dbf22a 395 PRINTS PR00359 B-class P450 signature 132 148 1.4E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12860 e6f967253db04e7bcc695078672fd037 502 SUPERFAMILY SSF47240 6 492 2.37E-140 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS12860 e6f967253db04e7bcc695078672fd037 502 Gene3D G3DSA:1.10.620.20 1 491 3.0E-128 T 29-03-2018 MSG_RS12860 e6f967253db04e7bcc695078672fd037 502 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 18 248 1.4E-71 T 29-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 MSG_RS12860 e6f967253db04e7bcc695078672fd037 502 Pfam PF04945 YHS domain 420 451 7.5E-8 T 29-03-2018 IPR007029 YHS domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2065 2080 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF00698 Acyl transferase domain 556 871 3.2E-97 T 29-03-2018 IPR014043 Acyl transferase MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF51735 1773 2009 5.41E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.50.720 1566 1683 2.0E-26 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.47.10 24 291 8.0E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.30.70.250 690 739 4.4E-10 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1456 1522 6.8E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF52151 556 680 2.88E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF52151 745 847 2.88E-62 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.50.720 1765 1990 1.9E-38 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.47.10 294 452 2.0E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00829 1439 1751 1.8E-156 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF50129 1434 1570 2.89E-32 T 29-03-2018 IPR011032 GroES-like MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF08659 KR domain 1775 1952 2.2E-58 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00823 Phosphopantetheine attachment site 2039 2110 1.5E-14 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.90.180.10 1684 1755 0.016 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:1.10.1200.10 2028 2116 2.7E-16 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF00550 Phosphopantetheine attachment site 2040 2106 8.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF47336 2031 2114 1.7E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.90.180.10 1415 1565 1.0E-34 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 520 3.2E-13 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 31 279 2.0E-86 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF00107 Zinc-binding dehydrogenase 1580 1670 5.9E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.366.10 556 689 7.1E-36 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF51735 1208 1413 1.93E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 287 400 8.5E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00825 Beta-ketoacyl synthase 32 454 9.2E-181 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF51735 1545 1710 1.85E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 558 853 4.6E-89 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00826 918 1078 6.3E-35 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.40.366.10 740 858 1.2E-21 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 192 208 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Pfam PF14765 Polyketide synthase dehydratase 918 1194 1.9E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 Gene3D G3DSA:3.10.129.10 924 1042 7.3E-8 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1775 1954 2.3E-46 T 29-03-2018 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF55048 679 744 3.79E-8 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS10910 230137b57f9b293af2ef584adaad2101 2116 SUPERFAMILY SSF53901 28 399 3.52E-93 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS14155 e3653069872de10805234e992aab2e12 376 Gene3D G3DSA:3.30.70.20 350 374 0.0065 T 29-03-2018 MSG_RS14155 e3653069872de10805234e992aab2e12 376 Gene3D G3DSA:3.30.70.20 275 349 3.2E-8 T 29-03-2018 MSG_RS14155 e3653069872de10805234e992aab2e12 376 Gene3D G3DSA:3.30.70.20 211 274 0.0073 T 29-03-2018 MSG_RS14155 e3653069872de10805234e992aab2e12 376 SUPERFAMILY SSF46548 258 371 1.03E-16 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS14155 e3653069872de10805234e992aab2e12 376 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 346 357 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS14155 e3653069872de10805234e992aab2e12 376 Pfam PF17179 4Fe-4S dicluster domain 265 360 4.3E-34 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS14155 e3653069872de10805234e992aab2e12 376 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 266 277 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 Gene3D G3DSA:3.40.50.300 16 204 1.9E-54 T 29-03-2018 MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 Pfam PF00625 Guanylate kinase 22 200 3.3E-39 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 SUPERFAMILY SSF52540 20 201 4.47E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 SMART SM00072 20 204 1.1E-71 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 Hamap MF_00328 Guanylate kinase [gmk]. 19 204 34.664 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 ProSitePatterns PS00856 Guanylate kinase-like signature. 55 72 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MSG_RS10255 0e463342a537913214fc83f0b40c3ef8 208 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 21 200 1.5E-63 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MSG_RS12865 4f32cdcabdd1f1b811324cccc56b20c4 81 Gene3D G3DSA:3.10.20.270 1 81 1.3E-25 T 29-03-2018 IPR009355 Toluene-4-monooxygenase system B MSG_RS12865 4f32cdcabdd1f1b811324cccc56b20c4 81 Pfam PF06234 Toluene-4-monooxygenase system protein B (TmoB) 3 80 2.0E-22 T 29-03-2018 IPR009355 Toluene-4-monooxygenase system B MSG_RS12865 4f32cdcabdd1f1b811324cccc56b20c4 81 SUPERFAMILY SSF110814 3 80 7.06E-18 T 29-03-2018 IPR009355 Toluene-4-monooxygenase system B MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 373 1.9E-187 T 29-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 302 3.7E-31 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 Gene3D G3DSA:3.20.20.70 13 374 3.2E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 SMART SM01240 19 374 3.3E-13 T 29-03-2018 MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 SUPERFAMILY SSF51412 116 371 4.97E-58 T 29-03-2018 MSG_RS05120 298637acbcfb5fef3ec6ddb39529de47 375 SUPERFAMILY SSF51412 6 75 4.97E-58 T 29-03-2018 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 SUPERFAMILY SSF53271 15 221 7.14E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 SUPERFAMILY SSF159501 245 660 4.36E-130 T 29-03-2018 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Pfam PF00156 Phosphoribosyl transferase domain 21 201 4.3E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 PIRSF PIRSF036794 222 666 2.5E-139 T 29-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Gene3D G3DSA:3.40.1660.10 427 659 1.7E-52 T 29-03-2018 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Gene3D G3DSA:3.40.50.2020 118 230 7.7E-19 T 29-03-2018 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Gene3D G3DSA:3.30.1870.10 293 375 3.0E-27 T 29-03-2018 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Pfam PF05139 Erythromycin esterase 291 654 2.1E-116 T 29-03-2018 IPR007815 Erythromycin esterase GO:0046677 MSG_RS13910 72cdcf4e1a6082728dfa507f02ee4f8c 679 Gene3D G3DSA:3.30.1310.20 67 117 3.6E-24 T 29-03-2018 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 SUPERFAMILY SSF69742 2 158 2.88E-42 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 PIRSF PIRSF000445 1 437 6.3E-137 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Gene3D G3DSA:3.40.50.720 161 323 8.3E-27 T 29-03-2018 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 156 3.2E-43 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 313 8.9E-30 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MSG_RS03590 9be99698fce4963b437d48da5100424b 466 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 427 9.1E-148 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Gene3D G3DSA:1.10.1200.70 340 427 7.0E-22 T 29-03-2018 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 SUPERFAMILY SSF69075 329 427 1.57E-15 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 330 426 1.5E-20 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS03590 9be99698fce4963b437d48da5100424b 466 SUPERFAMILY SSF51735 163 313 2.96E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03590 9be99698fce4963b437d48da5100424b 466 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 424 26.313 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Gene3D G3DSA:1.10.3260.10 63 219 1.1E-21 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Gene3D G3DSA:1.10.3260.10 2 62 0.31 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 211 219 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 497 3.2E-11 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Gene3D G3DSA:3.30.470.30 220 325 7.7E-25 T 29-03-2018 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 SUPERFAMILY SSF117018 5 199 9.94E-29 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Gene3D G3DSA:2.40.50.140 385 512 2.6E-33 T 29-03-2018 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Pfam PF04675 DNA ligase N terminus 63 139 3.6E-8 T 29-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Gene3D G3DSA:3.30.1490.70 326 384 1.9E-15 T 29-03-2018 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 SUPERFAMILY SSF50249 387 512 9.94E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 71 512 3.7E-77 T 29-03-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Pfam PF01068 ATP dependent DNA ligase domain 188 385 3.6E-44 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 SUPERFAMILY SSF56091 170 269 2.18E-41 T 29-03-2018 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 SUPERFAMILY SSF56091 298 386 2.18E-41 T 29-03-2018 MSG_RS07250 5c0af268f10f0de0d73d9c1802448753 512 Hamap MF_00407 DNA ligase [lig]. 1 512 26.245 T 29-03-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 Gene3D G3DSA:3.40.605.10 1 270 2.3E-79 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 Pfam PF00171 Aldehyde dehydrogenase family 19 479 4.2E-152 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 Gene3D G3DSA:3.40.309.10 271 465 9.6E-67 T 29-03-2018 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 SUPERFAMILY SSF53720 12 481 1.57E-149 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS17660 07e727787b606592f28f64dcc5e23b24 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 SUPERFAMILY SSF47384 211 284 1.65E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 SMART SM00387 330 438 5.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 Gene3D G3DSA:3.30.565.10 292 435 2.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 434 1.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 7.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 380 7.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 Gene3D G3DSA:1.10.287.130 205 291 6.4E-10 T 29-03-2018 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 SMART SM00388 222 288 8.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 285 7.1E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS00745 b7c6f8bb0c1cb042c37c7f61bb35f578 442 SUPERFAMILY SSF55874 295 434 8.77E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20755 82a7eb31adf4dc41c1775bf4b5cb2c8d 151 SUPERFAMILY SSF55961 7 150 4.64E-23 T 29-03-2018 MSG_RS20755 82a7eb31adf4dc41c1775bf4b5cb2c8d 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 149 2.3E-17 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS20755 82a7eb31adf4dc41c1775bf4b5cb2c8d 151 Gene3D G3DSA:3.30.530.20 3 151 1.2E-28 T 29-03-2018 IPR023393 START-like domain MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 17 33 4.6E-17 T 29-03-2018 MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 102 114 4.6E-17 T 29-03-2018 MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 40 54 4.6E-17 T 29-03-2018 MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 141 165 4.6E-17 T 29-03-2018 MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 SUPERFAMILY SSF53335 19 214 4.38E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 Gene3D G3DSA:3.40.50.150 19 230 1.1E-20 T 29-03-2018 MSG_RS05820 a844fa5ba097377f75fbd222adbf7d24 531 Gene3D G3DSA:3.90.220.10 260 472 4.5E-5 T 29-03-2018 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 SUPERFAMILY SSF46689 3 82 3.23E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 Gene3D G3DSA:1.10.357.10 48 194 4.2E-15 T 29-03-2018 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 Gene3D G3DSA:1.10.10.60 1 47 5.3E-16 T 29-03-2018 MSG_RS14240 74fc0cd2faa677c916de4a61c93c563e 223 SUPERFAMILY SSF48498 79 190 1.01E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19840 53a670f71d8e18fe39bbab37b6f76b89 222 Pfam PF04977 Septum formation initiator 83 158 6.4E-19 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 SMART SM00342 195 278 2.7E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 7.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 7.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 Pfam PF12833 Helix-turn-helix domain 202 280 6.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 232 274 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 SUPERFAMILY SSF46689 232 281 2.04E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 Gene3D G3DSA:2.60.120.10 9 100 7.1E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 Gene3D G3DSA:1.10.10.60 101 232 1.1E-6 T 29-03-2018 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 SUPERFAMILY SSF51182 47 159 4.0E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 Gene3D G3DSA:1.10.10.60 233 282 5.0E-14 T 29-03-2018 MSG_RS19915 f75e6244cc5205160af2d153e06721e3 291 Pfam PF02311 AraC-like ligand binding domain 42 113 2.2E-5 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MSG_RS15860 243a277ada1e99d159eefc77b1d928c8 103 Pfam PF02656 Domain of unknown function (DUF202) 1 63 1.1E-14 T 29-03-2018 IPR003807 Domain of unknown function DUF202 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Gene3D G3DSA:1.20.140.10 225 397 9.1E-52 T 29-03-2018 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 SUPERFAMILY SSF47203 235 386 1.29E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 SUPERFAMILY SSF56645 9 247 2.36E-69 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 PIRSF PIRSF016578 143 392 1.3E-10 T 29-03-2018 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 PIRSF PIRSF016578 2 88 5.3E-4 T 29-03-2018 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 1.3E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 1.0E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Gene3D G3DSA:2.40.110.10 126 224 1.4E-35 T 29-03-2018 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Gene3D G3DSA:1.10.540.10 7 125 5.2E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS18010 bb076113d504f4e692cbaf1517059f15 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 223 1.3E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 SUPERFAMILY SSF48498 98 204 2.4E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 4.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 Gene3D G3DSA:1.10.10.60 20 82 1.2E-16 T 29-03-2018 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 7.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 7.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 SUPERFAMILY SSF46689 22 92 2.57E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS16325 d4e0c62d90d36c0a155053b7fd025bef 208 Gene3D G3DSA:1.10.357.10 83 207 6.7E-14 T 29-03-2018 MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 SUPERFAMILY SSF46689 4 75 1.03E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 SUPERFAMILY SSF48498 73 185 2.96E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS09845 0b17f402277a75506896c6a2e6163f47 189 Gene3D G3DSA:1.10.357.10 2 188 1.7E-27 T 29-03-2018 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 Gene3D G3DSA:1.20.20.10 5 77 5.7E-14 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 PRINTS PR00124 ATP synthase C subunit signature 50 75 3.1E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 PRINTS PR00124 ATP synthase C subunit signature 12 31 3.1E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 PRINTS PR00124 ATP synthase C subunit signature 33 48 3.1E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 SUPERFAMILY SSF81333 5 78 7.72E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 Pfam PF00137 ATP synthase subunit C 11 70 2.6E-8 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 14.201 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18270 8ddc13aee3db4d1c1965de3b64866f78 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 77 3.6E-14 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 SUPERFAMILY SSF51735 2 159 1.88E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 155 2.6E-30 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 Gene3D G3DSA:1.10.1040.10 167 259 1.5E-13 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 SUPERFAMILY SSF48179 159 257 3.51E-13 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 PIRSF PIRSF000103 1 259 3.4E-50 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 247 1.7E-10 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MSG_RS21245 c48de32ef48da19c24bb2823eb8caaba 267 Gene3D G3DSA:3.40.50.720 1 166 3.3E-30 T 29-03-2018 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Pfam PF04539 Sigma-70 region 3 133 192 1.4E-10 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Gene3D G3DSA:1.10.10.10 195 273 2.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 SUPERFAMILY SSF88659 203 272 1.87E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 PRINTS PR00046 Major sigma-70 factor signature 77 90 1.9E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 PRINTS PR00046 Major sigma-70 factor signature 242 257 1.9E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 PRINTS PR00046 Major sigma-70 factor signature 225 237 1.9E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 PRINTS PR00046 Major sigma-70 factor signature 257 268 1.9E-8 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 47 272 1.6E-89 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 SUPERFAMILY SSF88946 21 122 9.81E-26 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 272 1.8E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Gene3D G3DSA:1.10.10.10 123 175 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 SUPERFAMILY SSF88659 126 193 1.31E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Gene3D G3DSA:1.10.1740.10 37 120 2.9E-17 T 29-03-2018 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Pfam PF04545 Sigma-70, region 4 223 270 1.5E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS12460 f9f90c92c8849aa743c496b6f938031d 273 Pfam PF04542 Sigma-70 region 2 54 122 2.8E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06940 836a3b4174caa2a56d3d013b6d58069d 404 SUPERFAMILY SSF55874 279 383 5.37E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06940 836a3b4174caa2a56d3d013b6d58069d 404 Pfam PF07730 Histidine kinase 203 266 2.8E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MSG_RS06940 836a3b4174caa2a56d3d013b6d58069d 404 Gene3D G3DSA:3.30.565.10 196 387 1.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06940 836a3b4174caa2a56d3d013b6d58069d 404 SMART SM00387 300 394 1.7E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20045 6230e79b89beaa23c60aa83b9478163e 487 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 296 471 8.1E-6 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS20045 6230e79b89beaa23c60aa83b9478163e 487 Pfam PF02706 Chain length determinant protein 1 89 1.7E-7 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MSG_RS20045 6230e79b89beaa23c60aa83b9478163e 487 Gene3D G3DSA:3.30.1890.10 32 144 9.7E-6 T 29-03-2018 MSG_RS20045 6230e79b89beaa23c60aa83b9478163e 487 Gene3D G3DSA:3.40.50.300 275 485 1.7E-27 T 29-03-2018 MSG_RS20045 6230e79b89beaa23c60aa83b9478163e 487 SUPERFAMILY SSF52540 293 475 6.28E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 259 395 3.6E-12 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SMART SM01043 98 241 2.7E-45 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 81 9.3E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:1.10.10.10 2 100 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF55073 255 428 2.98E-43 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:1.25.40.10 1105 1320 1.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.40.50.300 451 643 4.0E-9 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Pfam PF03704 Bacterial transcriptional activator domain 98 240 4.1E-35 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:1.25.40.10 101 256 5.4E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF54427 1329 1437 1.51E-6 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF52540 458 706 1.33E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SMART SM00044 203 407 1.6E-4 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.10.450.50 1321 1438 1.5E-11 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.10.450.50 1844 1990 1.9E-12 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Pfam PF13191 AAA ATPase domain 458 629 2.5E-27 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:1.25.40.10 810 1104 7.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF54427 1866 1989 8.28E-7 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF48452 1130 1263 6.48E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.10.450.50 1445 1592 6.9E-5 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.10.450.50 1593 1742 4.9E-8 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.10.450.50 1991 2128 5.5E-7 T 29-03-2018 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF48452 96 259 1.64E-34 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SUPERFAMILY SSF46894 9 92 6.52E-12 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 SMART SM00862 21 93 4.3E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS16215 8cc65f9a7e5af1eba6802d1a16942b30 2130 Gene3D G3DSA:3.30.70.1230 257 433 2.7E-34 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 173 3.2E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 240 248 3.2E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 PRINTS PR00410 Phenol hydroxylase reductase family signature 76 88 3.2E-10 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 SUPERFAMILY SSF63380 45 145 1.21E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 Pfam PF00970 Oxidoreductase FAD-binding domain 75 143 1.2E-8 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 Pfam PF00175 Oxidoreductase NAD-binding domain 155 254 2.7E-7 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 SUPERFAMILY SSF54292 259 363 4.33E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 Gene3D G3DSA:3.10.20.30 266 362 6.4E-12 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 Gene3D G3DSA:2.40.30.10 48 138 9.2E-18 T 29-03-2018 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 Gene3D G3DSA:3.40.50.80 140 265 7.5E-20 T 29-03-2018 MSG_RS01315 6e1ad98af3c6d0e786bb731859bc1699 363 SUPERFAMILY SSF52343 141 270 2.23E-24 T 29-03-2018 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF02151 UvrB/uvrC motif 425 459 2.8E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SUPERFAMILY SSF52540 171 470 2.01E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SMART SM00382 545 723 8.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SMART SM00382 208 353 8.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SUPERFAMILY SSF52540 494 807 2.81E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:1.10.1780.10 1 78 4.2E-27 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SUPERFAMILY SSF81923 3 144 1.37E-31 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 SMART SM01086 722 813 8.1E-36 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:3.40.50.300 500 721 3.2E-51 T 29-03-2018 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:3.40.50.300 202 350 1.8E-17 T 29-03-2018 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 2.0E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 2.0E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 2.0E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 2.0E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 716 8.3E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 8.0E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.2E-15 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 802 2.0E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 325 5.9E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:1.10.8.60 722 825 1.4E-23 T 29-03-2018 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 303 315 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:1.10.8.60 352 495 3.6E-43 T 29-03-2018 MSG_RS22800 a8bf846fa08a8b159126de36a7990499 843 Gene3D G3DSA:1.10.1780.10 79 201 6.1E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 Pfam PF00027 Cyclic nucleotide-binding domain 45 124 4.0E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 SUPERFAMILY SSF55729 161 299 2.84E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 SUPERFAMILY SSF51206 18 144 1.02E-19 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 Gene3D G3DSA:3.40.630.30 151 337 5.4E-18 T 29-03-2018 MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 SMART SM00100 25 145 2.1E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS20115 db58bac0da7ebc153593c73638485f51 338 Gene3D G3DSA:2.60.120.10 15 150 1.5E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS05270 e18c2527d72da1a02f212fa1f14e0237 134 Pfam PF03259 Roadblock/LC7 domain 8 98 2.0E-25 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain MSG_RS05270 e18c2527d72da1a02f212fa1f14e0237 134 SUPERFAMILY SSF103196 6 128 1.83E-32 T 29-03-2018 MSG_RS05270 e18c2527d72da1a02f212fa1f14e0237 134 SMART SM00960 9 99 6.8E-32 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain MSG_RS05270 e18c2527d72da1a02f212fa1f14e0237 134 Gene3D G3DSA:3.30.450.30 6 129 3.5E-38 T 29-03-2018 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 SUPERFAMILY SSF56645 8 252 4.06E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 6.1E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 SUPERFAMILY SSF47203 243 394 1.61E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Gene3D G3DSA:2.40.110.10 127 233 1.3E-29 T 29-03-2018 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 PIRSF PIRSF016578 9 197 7.0E-8 T 29-03-2018 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 PIRSF PIRSF016578 238 375 3.2E-9 T 29-03-2018 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Gene3D G3DSA:1.10.540.10 5 126 1.5E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 229 5.5E-23 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 392 2.8E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17990 98e4ff095d74cdc0071653eb0399a559 397 Gene3D G3DSA:1.20.140.10 234 397 1.5E-50 T 29-03-2018 MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 SMART SM00387 28 185 4.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 638 30.323 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 123 145 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 196 214 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 173 190 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 6 26 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 27 49 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 76 93 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PRINTS PR00775 90kDa heat shock protein signature 94 111 3.7E-55 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 Pfam PF00183 Hsp90 protein 233 639 4.9E-139 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 SUPERFAMILY SSF54211 243 496 1.74E-95 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 Gene3D G3DSA:3.30.565.10 2 232 7.3E-51 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 157 8.9E-12 T 29-03-2018 MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 SUPERFAMILY SSF55874 5 220 1.57E-59 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 PIRSF PIRSF002583 2 640 7.6E-223 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MSG_RS16145 6fac4565b665b5912ca4b53995d4454c 641 SUPERFAMILY SSF110942 521 637 1.7E-34 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:1.10.1200.10 5 97 3.6E-11 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF47336 9 115 2.09E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1197 1375 2.9E-17 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF00550 Phosphopantetheine attachment site 14 79 4.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF00550 Phosphopantetheine attachment site 1474 1540 1.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF47336 1466 1546 1.14E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF51735 1199 1423 2.37E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF52151 630 755 5.75E-54 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF52151 818 909 5.75E-54 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.40.47.10 364 525 1.6E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM01294 1476 1540 1.9E-4 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.30.70.250 754 808 4.8E-15 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.40.366.10 629 753 5.4E-33 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.40.50.720 1191 1447 7.3E-38 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF55048 753 815 1.96E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.40.47.10 98 361 1.8E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:1.10.1200.10 1454 1551 2.5E-16 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 477 584 4.2E-20 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 357 474 2.9E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF00698 Acyl transferase domain 631 944 6.9E-107 T 29-03-2018 IPR014043 Acyl transferase MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF53901 502 523 1.11E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF53901 98 470 1.11E-102 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SUPERFAMILY SSF51735 996 1185 6.89E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1499 1514 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM00823 Phosphopantetheine attachment site 1472 1544 4.5E-18 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM00823 Phosphopantetheine attachment site 12 83 5.2E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF08659 KR domain 1198 1373 5.3E-45 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM00825 Beta-ketoacyl synthase 102 527 2.5E-218 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 100 349 4.9E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 Gene3D G3DSA:3.40.366.10 809 931 7.2E-19 T 29-03-2018 MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 262 278 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS08055 c4b1c5b8507518db241c944ccd08f546 1585 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 633 927 7.9E-87 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 ProSitePatterns PS00436 Peroxidases active site signature. 105 116 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 SUPERFAMILY SSF48113 441 745 8.1E-116 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Gene3D G3DSA:1.10.520.10 71 228 1.1E-34 T 29-03-2018 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 SUPERFAMILY SSF48113 38 440 1.62E-141 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Gene3D G3DSA:1.10.420.10 242 408 7.6E-32 T 29-03-2018 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Gene3D G3DSA:1.10.420.10 613 721 3.0E-37 T 29-03-2018 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 39 745 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Pfam PF00141 Peroxidase 96 404 5.4E-44 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Pfam PF00141 Peroxidase 414 720 9.2E-40 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 269 279 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00458 Haem peroxidase superfamily signature 183 195 1.5E-18 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00458 Haem peroxidase superfamily signature 105 119 1.5E-18 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00458 Haem peroxidase superfamily signature 328 343 1.5E-18 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00458 Haem peroxidase superfamily signature 165 182 1.5E-18 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00458 Haem peroxidase superfamily signature 269 284 1.5E-18 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Hamap MF_01961 Catalase-peroxidase [katG]. 20 746 40.572 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 Gene3D G3DSA:1.10.520.10 451 612 1.1E-41 T 29-03-2018 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 82 107 9.3E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 67 80 9.3E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 277 300 9.3E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 490 516 9.3E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS13610 c74187b7875d2acdc496327445a0e2a3 746 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 41 63 9.3E-52 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MSG_RS12355 c392aeec806287b42a66c996b1e878b3 257 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 31 207 2.1E-33 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS12355 c392aeec806287b42a66c996b1e878b3 257 SMART SM01007 30 208 2.8E-34 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS12355 c392aeec806287b42a66c996b1e878b3 257 SUPERFAMILY SSF53639 30 228 1.96E-40 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS12355 c392aeec806287b42a66c996b1e878b3 257 Gene3D G3DSA:3.40.225.10 25 252 1.7E-40 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 582 8.2E-202 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Pfam PF01336 OB-fold nucleic acid binding domain 19 100 6.5E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Pfam PF02938 GAD domain 310 390 6.7E-12 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 SUPERFAMILY SSF55261 287 409 4.58E-33 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 584 31.801 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 219 1.8E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.8E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.8E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 189 201 1.8E-25 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Gene3D G3DSA:2.40.50.140 2 107 7.7E-25 T 29-03-2018 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 SUPERFAMILY SSF50249 3 104 5.52E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 557 1.6E-97 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 Gene3D G3DSA:3.30.930.10 130 586 9.0E-99 T 29-03-2018 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 SUPERFAMILY SSF55681 112 290 3.38E-97 T 29-03-2018 MSG_RS09800 c2c32aadc7f70c2d192d266bb9503be0 591 SUPERFAMILY SSF55681 414 584 3.38E-97 T 29-03-2018 MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 SUPERFAMILY SSF52540 14 244 3.9E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 PIRSF PIRSF039085 9 249 5.6E-95 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 Gene3D G3DSA:3.40.50.300 8 248 1.3E-71 T 29-03-2018 MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 Pfam PF00005 ABC transporter 28 174 2.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS00290 d45ec0da3efdc6ef838472126db7dd51 249 SMART SM00382 37 222 3.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 Pfam PF03652 Holliday junction resolvase 23 156 1.0E-41 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 22 158 23.005 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 SUPERFAMILY SSF53098 22 157 9.86E-35 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 Gene3D G3DSA:3.30.420.140 20 167 1.3E-43 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 SMART SM00732 22 123 1.1E-26 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MSG_RS09885 1c525729af1b31639dcfa6f6de218d04 176 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 25 155 1.2E-27 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 11 340 4.9E-194 T 29-03-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 Gene3D G3DSA:3.40.50.20 194 338 4.9E-7 T 29-03-2018 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 SUPERFAMILY SSF50129 7 181 6.29E-48 T 29-03-2018 IPR011032 GroES-like MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 Gene3D G3DSA:3.90.180.10 3 193 6.5E-56 T 29-03-2018 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 SMART SM00829 18 339 0.003 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 144 3.0E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS13025 03fb03e6d0e735eb9d9b1ecc5403f542 341 SUPERFAMILY SSF51735 152 309 1.21E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23365 432e59fe59956c31449c77201cee92ed 143 Pfam PF02566 OsmC-like protein 41 139 5.2E-18 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS23365 432e59fe59956c31449c77201cee92ed 143 Gene3D G3DSA:3.30.300.20 47 143 9.4E-24 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS23365 432e59fe59956c31449c77201cee92ed 143 Gene3D G3DSA:2.20.25.10 2 46 1.8E-19 T 29-03-2018 MSG_RS23365 432e59fe59956c31449c77201cee92ed 143 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 6 141 2.8E-52 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MSG_RS23365 432e59fe59956c31449c77201cee92ed 143 SUPERFAMILY SSF82784 4 142 3.8E-40 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF51230 1055 1130 4.97E-16 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:2.40.50.100 1061 1131 2.3E-15 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF52440 1 112 2.01E-40 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 327 1.2E-66 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 1.6E-39 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.10.600.10 461 527 3.6E-10 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF02436 Conserved carboxylase domain 824 1013 1.8E-54 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.20.20.70 528 843 1.7E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.30.470.20 208 451 1.5E-100 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF02785 Biotin carboxylase C-terminal domain 343 450 4.5E-36 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SMART SM00878 343 449 5.0E-55 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF56059 84 362 1.77E-64 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.10.600.10 971 1048 1.0E-20 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF51569 521 832 1.17E-76 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 PIRSF PIRSF001594 1 1131 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF89000 829 997 5.1E-39 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF00364 Biotin-requiring enzyme 1072 1130 6.7E-13 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 SUPERFAMILY SSF51246 337 454 8.37E-39 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1087 1104 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Pfam PF00682 HMGL-like 528 798 5.1E-27 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1130 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.40.50.20 1 121 5.0E-46 T 29-03-2018 MSG_RS07965 a64640b6a2a4fcde4ed1babd43dede12 1131 Gene3D G3DSA:3.30.1490.20 122 205 7.7E-16 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 SUPERFAMILY SSF51445 145 483 1.04E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 SUPERFAMILY SSF51445 512 586 1.04E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 SUPERFAMILY SSF51011 602 712 1.58E-26 T 29-03-2018 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 SUPERFAMILY SSF81296 17 159 3.64E-47 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Gene3D G3DSA:2.60.40.1180 591 715 7.2E-35 T 29-03-2018 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 22 108 1.9E-19 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 18 711 0.0 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Pfam PF00128 Alpha amylase, catalytic domain 313 542 5.6E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Pfam PF00128 Alpha amylase, catalytic domain 200 305 3.5E-10 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Gene3D G3DSA:3.20.20.80 149 590 8.6E-113 T 29-03-2018 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 SMART SM00642 170 578 3.0E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS06485 98b7f06a0fc89244365ceab6469c25d0 718 Gene3D G3DSA:2.60.40.10 18 148 8.6E-53 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 Gene3D G3DSA:2.40.37.10 228 390 3.4E-60 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 44 54 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 Pfam PF01168 Alanine racemase, N-terminal domain 21 243 4.4E-67 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 Gene3D G3DSA:3.20.20.10 15 227 3.9E-44 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 75 93 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 288 303 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 216 243 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 309 326 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 39 55 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 366 379 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 271 286 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 136 148 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 PRINTS PR00992 Alanine racemase signature 173 184 1.1E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 TIGRFAM TIGR00492 alr: alanine racemase 19 383 5.9E-92 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 SMART SM01005 255 384 3.0E-60 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 SUPERFAMILY SSF50621 249 385 2.65E-44 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 Pfam PF00842 Alanine racemase, C-terminal domain 255 382 1.5E-39 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 SUPERFAMILY SSF51419 21 256 2.62E-60 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS04985 2a4b7a9af4f390b96567d34b5e294aa6 390 Hamap MF_01201 Alanine racemase. 14 384 31.998 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Gene3D G3DSA:3.30.300.20 379 457 1.1E-29 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Gene3D G3DSA:1.20.120.430 97 271 1.7E-37 T 29-03-2018 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Gene3D G3DSA:1.20.120.430 10 96 2.1E-16 T 29-03-2018 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Gene3D G3DSA:1.20.120.430 272 378 3.7E-12 T 29-03-2018 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Pfam PF01926 50S ribosome-binding GTPase 204 322 3.9E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Pfam PF01926 50S ribosome-binding GTPase 32 146 7.8E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 SMART SM00382 28 166 0.73 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 SMART SM00382 201 419 1.6 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 203 368 4.5E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 179 3.1E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 30 456 2.5E-154 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 SUPERFAMILY SSF52540 31 191 1.56E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 PIRSF PIRSF006485 28 464 1.5E-161 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Hamap MF_00195 GTPase Der [der]. 29 459 34.571 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 378 456 5.4E-26 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 205 225 6.3E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 269 6.3E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS11770 b252af5f7278b1242bcc78751cbd58a3 466 SUPERFAMILY SSF52540 164 460 2.5E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 Gene3D G3DSA:3.40.50.300 323 535 2.6E-52 T 29-03-2018 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 2 525 8.8E-151 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 SUPERFAMILY SSF52540 321 527 1.46E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 Pfam PF00005 ABC transporter 341 483 3.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 Pfam PF00664 ABC transporter transmembrane region 8 262 7.4E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 SUPERFAMILY SSF90123 2 307 1.01E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 SMART SM00382 346 530 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 Gene3D G3DSA:1.20.1560.10 1 311 8.0E-30 T 29-03-2018 MSG_RS11275 4541dcc795f665fd9c342cc2c769f35a 537 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS22220 883dac1f8453de3e92d501596a5e1792 313 Pfam PF00378 Enoyl-CoA hydratase/isomerase 107 263 1.9E-25 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS22220 883dac1f8453de3e92d501596a5e1792 313 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 89 4.9E-11 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS22220 883dac1f8453de3e92d501596a5e1792 313 SUPERFAMILY SSF52096 22 293 4.18E-56 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS22220 883dac1f8453de3e92d501596a5e1792 313 Gene3D G3DSA:3.90.226.10 1 279 8.4E-54 T 29-03-2018 MSG_RS10580 0ba607822dc4237fecf931406113cce9 257 Gene3D G3DSA:3.40.50.300 1 257 4.8E-42 T 29-03-2018 MSG_RS10580 0ba607822dc4237fecf931406113cce9 257 SUPERFAMILY SSF52540 3 236 2.48E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10580 0ba607822dc4237fecf931406113cce9 257 Pfam PF00005 ABC transporter 25 176 4.5E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10580 0ba607822dc4237fecf931406113cce9 257 SMART SM00382 34 235 2.5E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10580 0ba607822dc4237fecf931406113cce9 257 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 248 2.0E-103 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 Gene3D G3DSA:1.20.1640.10 123 342 8.2E-26 T 29-03-2018 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 Gene3D G3DSA:1.20.1640.10 716 916 1.1E-23 T 29-03-2018 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 SUPERFAMILY SSF82866 716 919 6.02E-24 T 29-03-2018 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 Pfam PF03176 MMPL family 592 927 1.4E-98 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 Pfam PF03176 MMPL family 44 372 4.3E-109 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 TIGRFAM TIGR00833 actII: transport protein 11 919 8.8E-292 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS05415 b05c5ae83efbd3b5da3a852d17ab04ec 957 SUPERFAMILY SSF82866 141 339 1.44E-23 T 29-03-2018 MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 238 633 6.5E-166 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 Pfam PF00266 Aminotransferase class-V 256 625 2.0E-144 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 Gene3D G3DSA:3.40.640.10 265 513 4.0E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 Gene3D G3DSA:3.90.1150.10 514 632 3.6E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 448 467 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MSG_RS16565 3f0450aeff52b67b01877b93fe891f4e 640 SUPERFAMILY SSF53383 234 634 1.22E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 Gene3D G3DSA:1.10.10.60 19 73 1.7E-17 T 29-03-2018 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 Gene3D G3DSA:1.10.357.10 74 200 8.0E-23 T 29-03-2018 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 SUPERFAMILY SSF46689 21 78 2.86E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 190 1.6E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 SUPERFAMILY SSF48498 86 195 1.41E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 4.6E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07685 b593cd68c61d6e873d42c1f30ec7a1e8 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS18085 440707ad5828c3fdcbd8d1ebf51b0b37 223 SUPERFAMILY SSF144091 26 206 1.7E-28 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MSG_RS18085 440707ad5828c3fdcbd8d1ebf51b0b37 223 Pfam PF01694 Rhomboid family 57 203 7.4E-25 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MSG_RS18085 440707ad5828c3fdcbd8d1ebf51b0b37 223 Gene3D G3DSA:1.20.1540.10 15 203 1.8E-19 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00385 P450 superfamily signature 385 394 1.8E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00385 P450 superfamily signature 394 405 1.8E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00385 P450 superfamily signature 309 320 1.8E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00385 P450 superfamily signature 256 273 1.8E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 394 412 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 353 371 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 28 51 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 247 273 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 304 320 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 337 351 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 PRINTS PR00465 E-class P450 group IV signature 378 394 3.3E-34 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 387 396 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 Pfam PF00067 Cytochrome P450 17 443 2.7E-68 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 SUPERFAMILY SSF48264 16 448 3.14E-97 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22025 f244524649aebe1dba44bce06936d01f 450 Gene3D G3DSA:1.10.630.10 6 450 9.0E-102 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 Gene3D G3DSA:3.40.50.880 147 372 7.6E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 SMART SM01097 1 133 2.7E-76 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 368 1.2E-128 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 SUPERFAMILY SSF52317 153 369 3.06E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 371 43.599 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 Pfam PF00117 Glutamine amidotransferase class-I 185 365 6.1E-37 T 29-03-2018 IPR017926 Glutamine amidotransferase MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00097 Anthranilate synthase component II signature 223 232 5.9E-6 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00097 Anthranilate synthase component II signature 342 355 5.9E-6 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00097 Anthranilate synthase component II signature 251 262 5.9E-6 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 342 355 2.3E-11 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 262 2.3E-11 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 223 232 2.3E-11 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 293 304 3.6E-32 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 268 285 3.6E-32 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 220 234 3.6E-32 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 181 195 3.6E-32 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 267 3.6E-32 T 29-03-2018 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 SUPERFAMILY SSF52021 2 137 7.19E-50 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 Gene3D G3DSA:3.50.30.20 1 146 6.6E-57 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10235 2b83bfad7a113732ea01cc17b05f483f 376 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 131 1.4E-47 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS19000 35a6ad94f0442337d9ff44fbcc4e086f 286 SUPERFAMILY SSF53335 24 196 2.22E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19000 35a6ad94f0442337d9ff44fbcc4e086f 286 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 25 161 5.0E-14 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS19000 35a6ad94f0442337d9ff44fbcc4e086f 286 Pfam PF05050 Methyltransferase FkbM domain 27 193 1.2E-15 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS19000 35a6ad94f0442337d9ff44fbcc4e086f 286 Gene3D G3DSA:3.40.50.150 5 204 2.0E-16 T 29-03-2018 MSG_RS14900 53ce518202519041681012ea00f94c2a 293 Gene3D G3DSA:3.40.50.720 1 272 1.4E-59 T 29-03-2018 MSG_RS14900 53ce518202519041681012ea00f94c2a 293 SUPERFAMILY SSF51735 1 257 9.14E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14900 53ce518202519041681012ea00f94c2a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 Pfam PF00106 short chain dehydrogenase 7 196 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14900 53ce518202519041681012ea00f94c2a 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 2.1E-4 T 29-03-2018 MSG_RS08000 a7c6cb5a6c77c35113cd1243ff4494dd 405 Pfam PF03773 Predicted permease 24 334 2.9E-79 T 29-03-2018 IPR005524 Predicted permease DUF318 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Gene3D G3DSA:1.10.601.10 1 335 6.9E-80 T 29-03-2018 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 90 499 34.02 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 SUPERFAMILY SSF88659 339 412 1.96E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 459 485 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 SUPERFAMILY SSF88659 398 498 2.03E-26 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 290 303 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 262 487 1.5E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Pfam PF04542 Sigma-70 region 2 266 335 1.9E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Pfam PF04539 Sigma-70 region 3 345 420 1.7E-28 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 SUPERFAMILY SSF88946 194 336 7.4E-54 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Pfam PF00140 Sigma-70 factor, region 1.2 197 230 4.4E-16 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 262 498 6.2E-114 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Pfam PF04545 Sigma-70, region 4 434 487 2.6E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Gene3D G3DSA:1.10.10.10 336 386 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 PRINTS PR00046 Major sigma-70 factor signature 290 303 3.6E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 PRINTS PR00046 Major sigma-70 factor signature 438 450 3.6E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 PRINTS PR00046 Major sigma-70 factor signature 474 485 3.6E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 PRINTS PR00046 Major sigma-70 factor signature 459 474 3.6E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 PRINTS PR00046 Major sigma-70 factor signature 314 322 3.6E-29 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09035 cb51b8986a0ea81ad2f84583cb176ffe 499 Gene3D G3DSA:1.10.10.10 428 499 4.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 SUPERFAMILY SSF56645 5 206 1.31E-20 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 SUPERFAMILY SSF47203 214 357 6.28E-37 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 107 1.1E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 357 1.1E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 Gene3D G3DSA:1.20.140.10 198 360 5.0E-35 T 29-03-2018 MSG_RS08745 20b5f7a295f7825774e50ccdc6b2ed06 365 Gene3D G3DSA:1.10.540.10 2 120 5.6E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21990 a98bea3c3351999de7f5a2ba0a309be0 145 Gene3D G3DSA:1.20.1290.10 5 144 2.4E-17 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS21990 a98bea3c3351999de7f5a2ba0a309be0 145 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 101 2.3E-6 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS21990 a98bea3c3351999de7f5a2ba0a309be0 145 SUPERFAMILY SSF69118 3 112 2.68E-17 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 655 2.3E-234 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SUPERFAMILY SSF52540 992 1174 2.79E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 Gene3D G3DSA:3.40.50.300 734 954 1.2E-16 T 29-03-2018 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 Gene3D G3DSA:3.40.50.300 337 626 1.9E-20 T 29-03-2018 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 Gene3D G3DSA:3.40.50.300 985 1189 2.0E-6 T 29-03-2018 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SUPERFAMILY SSF52540 717 967 4.03E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 Pfam PF01580 FtsK/SpoIIIE family 741 976 3.1E-62 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 Pfam PF01580 FtsK/SpoIIIE family 400 535 3.4E-24 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SUPERFAMILY SSF52540 401 657 1.58E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 698 1240 4.8E-224 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SMART SM00382 767 941 0.98 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SMART SM00382 434 651 5.4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS04885 0e8599df13cdebcd5a7c063ee4834de6 1245 SMART SM00382 1036 1195 1.1 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 307 323 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 159 172 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 362 374 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 189 210 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 285 298 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PRINTS PR00471 Acetate kinase family signature 6 17 2.0E-44 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 TIGRFAM TIGR00016 ackA: acetate kinase 2 379 4.4E-123 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 SUPERFAMILY SSF53067 144 382 1.15E-79 T 29-03-2018 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 Hamap MF_00020 Acetate kinase [ackA]. 1 383 156.588 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 Pfam PF00871 Acetokinase family 6 375 2.1E-128 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 Gene3D G3DSA:3.30.420.40 182 383 7.3E-75 T 29-03-2018 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 SUPERFAMILY SSF53067 5 181 3.11E-57 T 29-03-2018 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 PIRSF PIRSF000722 2 383 1.7E-127 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 Gene3D G3DSA:3.30.420.40 5 181 3.7E-64 T 29-03-2018 MSG_RS02975 a4e0b1c92d5e436001eb8a0c8a0f58eb 383 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 189 206 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 SUPERFAMILY SSF46548 379 432 6.54E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 SUPERFAMILY SSF46548 280 316 6.54E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 Gene3D G3DSA:1.10.1060.10 262 440 9.4E-31 T 29-03-2018 MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 403 414 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 Gene3D G3DSA:1.20.950.20 4 246 6.9E-36 T 29-03-2018 MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 Pfam PF02754 Cysteine-rich domain 488 579 7.6E-17 T 29-03-2018 IPR004017 Cysteine-rich domain MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 Pfam PF02754 Cysteine-rich domain 618 704 3.0E-17 T 29-03-2018 IPR004017 Cysteine-rich domain MSG_RS02660 3983f8291af001602f2751f7a926f81d 957 Pfam PF13183 4Fe-4S dicluster domain 292 417 3.2E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 Pfam PF06426 Serine acetyltransferase, N-terminal 2 35 1.9E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 PIRSF PIRSF000441 1 215 2.5E-80 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 2.2E-73 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 Gene3D G3DSA:1.10.3130.10 1 58 2.4E-22 T 29-03-2018 MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 6.0E-10 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 SUPERFAMILY SSF51161 4 170 6.65E-54 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS16585 39e8c8a98c6a668b849f0ed9a119c851 228 Gene3D G3DSA:2.160.10.10 59 214 7.8E-37 T 29-03-2018 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Pfam PF00152 tRNA synthetases class II (D, K and N) 824 1167 3.1E-67 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 687 1170 1.1E-136 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 SUPERFAMILY SSF55681 823 1168 6.13E-97 T 29-03-2018 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Gene3D G3DSA:3.30.930.10 817 1168 6.4E-84 T 29-03-2018 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Pfam PF01336 OB-fold nucleic acid binding domain 729 807 1.0E-12 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Gene3D G3DSA:3.40.630.30 417 565 8.3E-6 T 29-03-2018 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 PRINTS PR00982 Lysyl-tRNA synthetase signature 905 918 2.4E-31 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 PRINTS PR00982 Lysyl-tRNA synthetase signature 860 870 2.4E-31 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 PRINTS PR00982 Lysyl-tRNA synthetase signature 876 892 2.4E-31 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 PRINTS PR00982 Lysyl-tRNA synthetase signature 923 940 2.4E-31 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 PRINTS PR00982 Lysyl-tRNA synthetase signature 1054 1070 2.4E-31 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Gene3D G3DSA:2.40.50.140 685 816 1.9E-25 T 29-03-2018 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 691 1171 34.37 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 SUPERFAMILY SSF50249 684 815 3.43E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 312 610 7.2E-101 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal MSG_RS11445 279aed76b2bc7863679e019612ef0489 1171 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 79 293 5.1E-79 T 29-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 MSG_RS15310 df47dc839bc6ef872e57f0f0c0596678 555 SUPERFAMILY SSF81342 20 299 9.73E-58 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MSG_RS15310 df47dc839bc6ef872e57f0f0c0596678 555 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 120 294 1.5E-59 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MSG_RS15310 df47dc839bc6ef872e57f0f0c0596678 555 Gene3D G3DSA:1.20.810.10 19 441 7.5E-98 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 Gene3D G3DSA:1.10.1040.10 165 289 4.2E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 SUPERFAMILY SSF51735 1 160 1.81E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 1 286 2.2E-54 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 SUPERFAMILY SSF48179 165 285 2.82E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 Pfam PF02558 Ketopantoate reductase PanE/ApbA 1 138 3.7E-26 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 165 285 2.6E-20 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MSG_RS09790 77994003dead9d07ca173e17c4acdd01 291 Gene3D G3DSA:3.40.50.720 1 164 3.1E-24 T 29-03-2018 MSG_RS05805 77d171374702c12773ae35d8ac0675cf 296 SUPERFAMILY SSF53448 7 263 2.55E-44 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS05805 77d171374702c12773ae35d8ac0675cf 296 Gene3D G3DSA:3.90.550.10 5 293 7.8E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS05805 77d171374702c12773ae35d8ac0675cf 296 Pfam PF00535 Glycosyl transferase family 2 7 192 5.8E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS14400 b8a4e8c56e60ed7e0a1e9e09e8d715a1 392 Gene3D G3DSA:1.10.287.1060 22 105 9.8E-5 T 29-03-2018 MSG_RS14400 b8a4e8c56e60ed7e0a1e9e09e8d715a1 392 Pfam PF00823 PPE family 6 160 6.9E-50 T 29-03-2018 IPR000030 PPE family MSG_RS14400 b8a4e8c56e60ed7e0a1e9e09e8d715a1 392 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 266 346 2.5E-13 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS14400 b8a4e8c56e60ed7e0a1e9e09e8d715a1 392 SUPERFAMILY SSF140459 2 170 1.67E-50 T 29-03-2018 MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.2E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 SUPERFAMILY SSF51735 20 249 1.75E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.5E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 247 1.7E-56 T 29-03-2018 MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 Gene3D G3DSA:3.40.50.720 14 55 2.4E-8 T 29-03-2018 MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 Gene3D G3DSA:3.40.50.720 56 251 9.7E-64 T 29-03-2018 MSG_RS10675 1a124793f5fb9aa086157caf5762505a 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 193 7.3E-7 T 29-03-2018 MSG_RS04765 53bc67794a08453a2f92b42a72cd8d56 231 SUPERFAMILY SSF50022 89 223 6.42E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04765 53bc67794a08453a2f92b42a72cd8d56 231 Pfam PF00355 Rieske [2Fe-2S] domain 123 198 3.3E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04765 53bc67794a08453a2f92b42a72cd8d56 231 Gene3D G3DSA:2.102.10.10 120 231 2.8E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 SUPERFAMILY SSF50998 26 105 4.32E-5 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 Gene3D G3DSA:2.120.10.30 119 267 1.6E-21 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 Gene3D G3DSA:2.120.10.30 19 118 3.5E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 Gene3D G3DSA:2.120.10.30 268 409 5.4E-14 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 SUPERFAMILY SSF101898 271 537 1.33E-27 T 29-03-2018 MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 40 259 2.8E-12 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 SUPERFAMILY SSF63829 83 303 3.86E-35 T 29-03-2018 MSG_RS01120 219c7483506a934dbcb75066204e5e88 542 Gene3D G3DSA:2.120.10.30 410 537 2.0E-11 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 Gene3D G3DSA:1.10.10.10 2 76 2.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 SMART SM00346 16 103 3.7E-25 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 Pfam PF09339 IclR helix-turn-helix domain 19 67 1.5E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 SUPERFAMILY SSF55781 80 242 2.75E-28 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 Pfam PF01614 Bacterial transcriptional regulator 131 243 4.0E-22 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 Gene3D G3DSA:3.30.450.40 79 243 7.9E-30 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12585 d92cf3d614a449ee3e0121c4706858c9 248 SUPERFAMILY SSF46785 16 85 4.64E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 SUPERFAMILY SSF57716 228 272 5.99E-11 T 29-03-2018 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 2.1E-7 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 SUPERFAMILY SSF46946 139 219 1.57E-20 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 Gene3D G3DSA:3.20.190.10 1 140 1.3E-18 T 29-03-2018 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 85 5.0E-10 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 SMART SM01232 139 229 5.4E-25 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 SUPERFAMILY SSF81624 2 144 4.19E-20 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 139 220 5.6E-17 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 Gene3D G3DSA:1.10.8.50 141 282 2.1E-34 T 29-03-2018 MSG_RS20400 2ba6a4e72f292e2b6bbfd9d0810a2631 287 SMART SM00898 2 125 7.1E-19 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 Gene3D G3DSA:1.10.1040.20 178 290 2.0E-28 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 Pfam PF10728 Domain of unknown function (DUF2520) 145 286 5.3E-37 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 Pfam PF10727 Rossmann-like domain 8 128 5.7E-59 T 29-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 SUPERFAMILY SSF48179 179 292 2.28E-17 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 SUPERFAMILY SSF51735 13 176 1.05E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22830 71982d1b1b6f42227f5be2d6af79f2af 303 Gene3D G3DSA:3.40.50.720 10 177 1.7E-19 T 29-03-2018 MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 3 220 41.777 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 97 104 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 222 1.9E-80 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 219 3.2E-71 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 Gene3D G3DSA:3.90.550.10 3 222 2.7E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS22730 e00a4d1efb0a2889c683792cc3c24341 222 SUPERFAMILY SSF53448 4 220 5.63E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS19955 64961710735c7ea7231501738ff66e93 121 SMART SM00091 7 74 8.5E-4 T 29-03-2018 IPR000014 PAS domain MSG_RS19955 64961710735c7ea7231501738ff66e93 121 Pfam PF00989 PAS fold 12 111 4.4E-10 T 29-03-2018 IPR013767 PAS fold GO:0006355 MSG_RS19955 64961710735c7ea7231501738ff66e93 121 Gene3D G3DSA:3.30.450.20 5 120 8.2E-15 T 29-03-2018 MSG_RS19955 64961710735c7ea7231501738ff66e93 121 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 120 3.9E-12 T 29-03-2018 IPR000014 PAS domain MSG_RS19955 64961710735c7ea7231501738ff66e93 121 SUPERFAMILY SSF55785 12 114 1.55E-14 T 29-03-2018 IPR000014 PAS domain MSG_RS08410 b833da1ae0b1360de8b83e9156b80ebb 284 SUPERFAMILY SSF55729 144 278 1.63E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS08410 b833da1ae0b1360de8b83e9156b80ebb 284 Pfam PF08445 FR47-like protein 214 275 9.5E-9 T 29-03-2018 IPR013653 FR47-like GO:0016747 MSG_RS08410 b833da1ae0b1360de8b83e9156b80ebb 284 Pfam PF13312 Domain of unknown function (DUF4081) 54 156 3.3E-41 T 29-03-2018 IPR025289 Domain of unknown function DUF4081 MSG_RS08410 b833da1ae0b1360de8b83e9156b80ebb 284 PIRSF PIRSF021603 1 283 3.1E-135 T 29-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like MSG_RS08410 b833da1ae0b1360de8b83e9156b80ebb 284 Gene3D G3DSA:3.40.630.30 141 281 1.7E-16 T 29-03-2018 MSG_RS13285 27f3a8f3cfd0f507df31c42d80273f2d 143 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 143 30.743 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MSG_RS13285 27f3a8f3cfd0f507df31c42d80273f2d 143 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 142 2.5E-42 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MSG_RS13285 27f3a8f3cfd0f507df31c42d80273f2d 143 SUPERFAMILY SSF69500 1 142 7.06E-46 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MSG_RS13285 27f3a8f3cfd0f507df31c42d80273f2d 143 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 142 1.5E-49 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MSG_RS13285 27f3a8f3cfd0f507df31c42d80273f2d 143 Gene3D G3DSA:3.50.80.10 1 143 2.4E-49 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SUPERFAMILY SSF52540 4 224 2.41E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SUPERFAMILY SSF52540 346 393 2.41E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SUPERFAMILY SSF81767 223 346 1.96E-43 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SUPERFAMILY SSF52540 395 611 1.56E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 97 111 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 317 339 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 391 404 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 113 123 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 166 186 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 59 83 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 PRINTS PR00906 SecA protein signature 354 371 1.2E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SUPERFAMILY SSF81886 614 831 1.27E-73 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 ProSitePatterns PS01312 SecA family signature. 478 493 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Gene3D G3DSA:3.40.50.300 284 394 1.0E-9 T 29-03-2018 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Gene3D G3DSA:3.40.50.300 5 267 2.2E-52 T 29-03-2018 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 833 19.844 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Gene3D G3DSA:3.40.50.300 395 626 2.0E-51 T 29-03-2018 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Pfam PF07516 SecA Wing and Scaffold domain 610 830 1.6E-66 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Gene3D G3DSA:1.10.3060.10 627 708 5.0E-29 T 29-03-2018 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SMART SM00957 2 380 7.1E-279 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 SMART SM00958 224 336 1.6E-61 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Pfam PF01043 SecA preprotein cross-linking domain 229 336 9.4E-36 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 24 817 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Pfam PF07517 SecA DEAD-like domain 6 379 7.1E-129 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MSG_RS05930 56e9f2332ed3c74471d314a63f4f1bd7 936 Gene3D G3DSA:3.10.450.50 712 935 1.5E-34 T 29-03-2018 MSG_RS21945 e058dac32860e19753c70851a247672e 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 9 286 1.4E-68 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MSG_RS21945 e058dac32860e19753c70851a247672e 297 Gene3D G3DSA:3.30.470.20 103 238 1.6E-51 T 29-03-2018 MSG_RS21945 e058dac32860e19753c70851a247672e 297 Gene3D G3DSA:3.30.200.20 5 102 3.7E-33 T 29-03-2018 MSG_RS21945 e058dac32860e19753c70851a247672e 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 8 286 23.967 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS21945 e058dac32860e19753c70851a247672e 297 SUPERFAMILY SSF56104 6 289 1.11E-94 T 29-03-2018 MSG_RS21945 e058dac32860e19753c70851a247672e 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 95 109 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS21945 e058dac32860e19753c70851a247672e 297 ProSitePatterns PS01058 SAICAR synthetase signature 2. 194 202 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS21945 e058dac32860e19753c70851a247672e 297 Pfam PF01259 SAICAR synthetase 11 258 1.9E-94 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS00570 ffeb42e7b251f4b0af2d26373c12c3e3 283 SUPERFAMILY SSF51679 3 277 1.01E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00570 ffeb42e7b251f4b0af2d26373c12c3e3 283 TIGRFAM TIGR03854 F420_MSMEG_3544: probable F420-dependent oxidoreductase, MSMEG_3544 family 4 283 8.9E-139 T 29-03-2018 IPR022402 F420-dependent oxidoreductase-predicted, MSMEG3544 MSG_RS00570 ffeb42e7b251f4b0af2d26373c12c3e3 283 Gene3D G3DSA:3.20.20.30 4 281 8.0E-45 T 29-03-2018 MSG_RS00570 ffeb42e7b251f4b0af2d26373c12c3e3 283 Pfam PF00296 Luciferase-like monooxygenase 3 215 3.7E-29 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS06045 1ed47cf6a5aa02676a62feb5deb4bc5b 121 Pfam PF02583 Metal-sensitive transcriptional repressor 9 87 7.9E-25 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 377 389 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 SUPERFAMILY SSF56112 255 543 7.55E-67 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:1.10.510.10 327 587 1.4E-41 T 29-03-2018 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:1.10.510.10 81 156 1.8E-17 T 29-03-2018 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 SUPERFAMILY SSF56112 8 230 4.72E-46 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Pfam PF01436 NHL repeat 597 623 2.4E-5 T 29-03-2018 IPR001258 NHL repeat GO:0005515 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Pfam PF01436 NHL repeat 775 800 8.9E-6 T 29-03-2018 IPR001258 NHL repeat GO:0005515 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Pfam PF01436 NHL repeat 816 841 2.5E-6 T 29-03-2018 IPR001258 NHL repeat GO:0005515 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:2.120.10.30 591 707 6.9E-13 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:2.120.10.30 708 842 2.3E-16 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Pfam PF00069 Protein kinase domain 259 461 1.4E-44 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Pfam PF00069 Protein kinase domain 13 155 3.6E-23 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 264 287 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 SUPERFAMILY SSF63829 587 842 2.09E-28 T 29-03-2018 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 SMART SM00220 258 519 3.0E-48 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 SMART SM00220 12 238 9.5E-28 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:1.10.510.10 157 226 1.9E-6 T 29-03-2018 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:3.30.200.20 227 326 2.4E-17 T 29-03-2018 MSG_RS05460 ea3a713d099bcfee5c6f3e45b20bd8b0 845 Gene3D G3DSA:3.30.200.20 5 80 5.5E-18 T 29-03-2018 MSG_RS05770 486031a12372acb382c4066c32026d77 258 Gene3D G3DSA:3.40.50.720 1 256 3.7E-52 T 29-03-2018 MSG_RS05770 486031a12372acb382c4066c32026d77 258 Pfam PF00106 short chain dehydrogenase 5 189 1.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 9.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 9.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.4E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05770 486031a12372acb382c4066c32026d77 258 PIRSF PIRSF000126 1 258 6.8E-64 T 29-03-2018 MSG_RS05770 486031a12372acb382c4066c32026d77 258 SUPERFAMILY SSF51735 3 249 5.0E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 Gene3D G3DSA:3.40.47.10 212 353 9.5E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 219 351 5.6E-16 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 PIRSF PIRSF000451 1 353 8.6E-112 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 10 199 2.6E-19 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 Gene3D G3DSA:3.40.47.10 1 207 2.8E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11535 a85ee40f4cb32ce571dba1a1748d5514 353 SUPERFAMILY SSF53901 3 352 5.07E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22335 dcb084ea1111bfea0cd3c32347da3e1d 255 PIRSF PIRSF006221 1 255 9.6E-50 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MSG_RS22335 dcb084ea1111bfea0cd3c32347da3e1d 255 SUPERFAMILY SSF56112 4 242 9.77E-32 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS22335 dcb084ea1111bfea0cd3c32347da3e1d 255 Gene3D G3DSA:1.10.510.10 121 217 4.0E-20 T 29-03-2018 MSG_RS22335 dcb084ea1111bfea0cd3c32347da3e1d 255 Pfam PF03881 Fructosamine kinase 4 250 3.8E-35 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MSG_RS22335 dcb084ea1111bfea0cd3c32347da3e1d 255 Gene3D G3DSA:3.30.200.20 2 46 2.4E-8 T 29-03-2018 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 33.698 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Gene3D G3DSA:3.10.290.10 97 139 5.1E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 6.1E-81 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Pfam PF01479 S4 domain 92 137 3.1E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 SMART SM01390 3 90 4.7E-42 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 SUPERFAMILY SSF55174 3 201 1.57E-60 T 29-03-2018 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 SMART SM00363 91 153 6.7E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Gene3D G3DSA:1.10.1050.10 1 96 6.5E-39 T 29-03-2018 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Gene3D G3DSA:1.10.1050.10 140 201 3.9E-12 T 29-03-2018 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 2.5E-27 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MSG_RS04840 bb4c51b0aeea2ecf51982e705b1b1768 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 19 323 3.5E-85 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 Gene3D G3DSA:3.30.1330.10 13 157 2.5E-28 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 43 152 3.6E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 166 254 2.2E-6 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 PIRSF PIRSF005303 13 323 5.4E-97 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 SUPERFAMILY SSF55326 15 152 1.92E-30 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 Gene3D G3DSA:3.90.650.10 161 323 7.9E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 18 320 28.847 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MSG_RS07875 3ab408fde1cdd3726e3f426f13fa6e54 325 SUPERFAMILY SSF56042 159 311 3.14E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Gene3D G3DSA:1.10.3090.10 345 597 2.5E-37 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 SUPERFAMILY SSF109604 408 515 5.96E-14 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Gene3D G3DSA:3.30.70.260 736 821 5.0E-8 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Gene3D G3DSA:3.30.70.260 615 704 2.5E-8 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 SUPERFAMILY SSF81301 58 166 7.63E-14 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 PIRSF PIRSF006288 8 606 4.0E-155 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 PIRSF PIRSF006288 597 815 1.3E-25 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Pfam PF08335 GlnD PII-uridylyltransferase 178 296 5.0E-7 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 37 597 2.2E-189 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Gene3D G3DSA:3.30.460.10 40 163 8.7E-8 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 819 62.92 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Pfam PF01966 HD domain 442 559 7.8E-10 T 29-03-2018 IPR006674 HD domain MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 SMART SM00471 437 570 1.1E-7 T 29-03-2018 IPR003607 HD/PDEase domain MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 SUPERFAMILY SSF81593 196 297 4.79E-5 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 SUPERFAMILY SSF55021 740 810 3.71E-7 T 29-03-2018 MSG_RS08135 edbd613e5d4489b96a65a66133a885b2 822 Gene3D G3DSA:1.20.120.330 164 305 3.2E-5 T 29-03-2018 MSG_RS04155 b0f2ee85f292e436937b1718779f3182 440 SUPERFAMILY SSF56112 182 307 6.34E-30 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS04155 b0f2ee85f292e436937b1718779f3182 440 SUPERFAMILY SSF56112 86 148 6.34E-30 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS04155 b0f2ee85f292e436937b1718779f3182 440 Pfam PF03109 ABC1 family 102 222 8.8E-35 T 29-03-2018 IPR004147 UbiB domain MSG_RS04155 b0f2ee85f292e436937b1718779f3182 440 Gene3D G3DSA:3.30.200.20 92 236 2.7E-23 T 29-03-2018 MSG_RS04155 b0f2ee85f292e436937b1718779f3182 440 Gene3D G3DSA:1.10.510.10 246 385 6.1E-6 T 29-03-2018 MSG_RS03555 4eaec8c79e45833a383a0d084bf2d996 306 Gene3D G3DSA:3.40.50.1000 54 281 2.3E-20 T 29-03-2018 IPR023214 HAD-like domain MSG_RS03555 4eaec8c79e45833a383a0d084bf2d996 306 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 56 246 6.5E-15 T 29-03-2018 MSG_RS03555 4eaec8c79e45833a383a0d084bf2d996 306 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 56 257 9.2E-57 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MSG_RS03555 4eaec8c79e45833a383a0d084bf2d996 306 Pfam PF12710 haloacid dehalogenase-like hydrolase 57 243 7.0E-26 T 29-03-2018 MSG_RS03555 4eaec8c79e45833a383a0d084bf2d996 306 SUPERFAMILY SSF56784 56 276 1.19E-28 T 29-03-2018 IPR023214 HAD-like domain MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 Gene3D G3DSA:1.10.357.10 81 208 3.6E-10 T 29-03-2018 MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 74 4.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 SUPERFAMILY SSF48498 98 207 1.48E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 Gene3D G3DSA:1.10.10.60 12 51 7.1E-10 T 29-03-2018 MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 Gene3D G3DSA:1.10.260.40 52 80 2.7E-8 T 29-03-2018 MSG_RS03385 55bebe9c34d7cdf1d82f6e23f3023350 233 SUPERFAMILY SSF46689 16 83 6.48E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 90 200 2.0E-16 T 29-03-2018 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 3.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 SUPERFAMILY SSF46689 8 93 1.12E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 Gene3D G3DSA:1.10.10.60 6 68 4.1E-19 T 29-03-2018 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 Gene3D G3DSA:1.10.357.10 69 205 3.0E-16 T 29-03-2018 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 SUPERFAMILY SSF48498 87 195 1.19E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10085 ca830d9bc9b7d74bb211874a2d4b744a 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12855 3b5a3241c96aca83680e8d93e94350db 163 SUPERFAMILY SSF53056 4 160 3.79E-38 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS12855 3b5a3241c96aca83680e8d93e94350db 163 Pfam PF00484 Carbonic anhydrase 31 119 2.2E-12 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS12855 3b5a3241c96aca83680e8d93e94350db 163 SMART SM00947 23 162 6.6E-30 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS12855 3b5a3241c96aca83680e8d93e94350db 163 Gene3D G3DSA:3.40.1050.10 1 163 1.0E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 Gene3D G3DSA:3.40.50.970 328 551 1.5E-21 T 29-03-2018 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 Gene3D G3DSA:3.40.50.970 1 197 2.2E-52 T 29-03-2018 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 185 4.6E-28 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 SUPERFAMILY SSF52518 353 535 4.05E-15 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 552 30.554 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 418 4.1E-102 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 SUPERFAMILY SSF52518 4 194 3.2E-30 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS03845 92567ce8c7960bfa6a1db0a6ff21fa61 552 PIRSF PIRSF004983 1 552 4.3E-149 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 121 1.3E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Gene3D G3DSA:1.10.540.10 1 123 2.3E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Gene3D G3DSA:1.20.140.10 223 385 4.1E-27 T 29-03-2018 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 SUPERFAMILY SSF56645 2 244 1.83E-60 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 SUPERFAMILY SSF47203 234 382 1.93E-14 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 221 2.5E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Gene3D G3DSA:2.40.110.10 124 222 1.9E-26 T 29-03-2018 MSG_RS17735 0ccfe4dd4af7c003344df71d37f7cc32 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 380 1.1E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 282 5.7E-72 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Pfam PF01926 50S ribosome-binding GTPase 9 111 4.4E-19 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 100 9.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 9 29 9.1E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 SUPERFAMILY SSF52540 9 213 1.33E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Pfam PF07650 KH domain 209 288 1.1E-19 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 SUPERFAMILY SSF54814 183 299 3.27E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Hamap MF_00367 GTPase Era [era]. 4 299 35.063 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Gene3D G3DSA:3.40.50.300 55 176 5.0E-16 T 29-03-2018 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 169 6.5E-18 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Gene3D G3DSA:3.30.300.20 186 299 9.5E-43 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS16700 7e9ba7b3a62225a7aded459ff433b954 299 Gene3D G3DSA:3.40.50.300 4 54 8.6E-16 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF00550 Phosphopantetheine attachment site 1150 1218 4.7E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF00550 Phosphopantetheine attachment site 1386 1454 2.7E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF00550 Phosphopantetheine attachment site 1268 1336 4.7E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:1.10.1200.10 1263 1350 1.5E-12 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:1.10.1200.10 1145 1232 1.5E-12 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:1.10.1200.10 1381 1465 1.7E-13 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF53901 4 125 1.09E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF53901 181 407 1.09E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF47336 1263 1344 1.44E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SMART SM00826 1979 2131 0.0076 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF14765 Polyketide synthase dehydratase 1993 2243 7.0E-28 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.47.10 1 296 8.3E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.366.10 760 896 1.5E-30 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.50.720 1478 1662 0.014 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SMART SM00825 Beta-ketoacyl synthase 8 465 2.7E-101 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.50.720 1690 1967 1.5E-37 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF00698 Acyl transferase domain 577 869 3.0E-37 T 29-03-2018 IPR014043 Acyl transferase MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1698 1925 1.4E-30 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF47336 1145 1226 1.44E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 285 2.7E-61 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF51735 1781 1960 8.0E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF51735 1698 1739 8.0E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.366.10 570 722 5.5E-31 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 577 883 1.7E-45 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF08659 KR domain 1700 1923 6.6E-32 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 508 2.3E-8 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF52151 776 878 3.4E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF52151 574 710 3.4E-57 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.10.129.10 1978 2103 3.7E-4 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF55048 711 774 4.97E-13 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.30.70.250 723 759 2.5E-16 T 29-03-2018 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Gene3D G3DSA:3.40.47.10 300 463 2.2E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 SUPERFAMILY SSF47336 1381 1476 2.49E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS07990 035a4f4dee8869b7be135bef11f4fab1 2245 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 411 2.9E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 154 169 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 289 316 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 272 283 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 338 347 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 347 358 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 137 153 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 317 332 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 PRINTS PR00359 B-class P450 signature 191 213 2.9E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 Gene3D G3DSA:1.10.630.10 3 401 1.0E-71 T 29-03-2018 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 Pfam PF00067 Cytochrome P450 47 367 1.7E-28 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17810 200a31c6e9f66ef0ad264aabcbcc3a77 404 SUPERFAMILY SSF48264 15 402 1.96E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 489 4.7E-233 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 8 490 5.8E-206 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 5 491 49.5 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 Gene3D G3DSA:3.50.50.60 2 487 1.4E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 SUPERFAMILY SSF51905 164 322 8.42E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08470 c6a2626a2398397b201a7ee41868abd9 494 SUPERFAMILY SSF51905 7 131 8.42E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10460 98888eef0113e38396213af381910364 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 38.955 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10460 98888eef0113e38396213af381910364 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10460 98888eef0113e38396213af381910364 261 Gene3D G3DSA:3.20.20.70 1 257 3.3E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS10460 98888eef0113e38396213af381910364 261 SUPERFAMILY SSF51351 2 253 1.11E-87 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10460 98888eef0113e38396213af381910364 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 6.2E-56 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10460 98888eef0113e38396213af381910364 261 Pfam PF00121 Triosephosphate isomerase 6 251 7.8E-87 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 Gene3D G3DSA:1.20.1640.10 155 380 1.1E-29 T 29-03-2018 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 TIGRFAM TIGR00833 actII: transport protein 36 945 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 SUPERFAMILY SSF82866 169 366 1.44E-26 T 29-03-2018 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 Pfam PF03176 MMPL family 618 953 1.0E-97 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 Pfam PF03176 MMPL family 69 398 2.8E-112 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 SUPERFAMILY SSF82866 736 945 4.58E-28 T 29-03-2018 MSG_RS03275 1cd1f9dbe335ef888fa394833b11c7c6 973 Gene3D G3DSA:1.20.1640.10 727 942 7.5E-24 T 29-03-2018 MSG_RS00210 30089f50314c1bc1828ba84693a62d3e 100 Pfam PF10904 Protein of unknown function (DUF2694) 1 97 9.7E-53 T 29-03-2018 IPR024426 Protein of unknown function DUF2694 MSG_RS00210 30089f50314c1bc1828ba84693a62d3e 100 ProDom PD068262 MB0029 RV0028/MT0030.1 1 99 7.0E-48 T 29-03-2018 IPR024426 Protein of unknown function DUF2694 MSG_RS23310 9ce8173f452c0de442b311c42925e7c2 285 Pfam PF06271 RDD family 18 144 1.2E-14 T 29-03-2018 IPR010432 RDD MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 Gene3D G3DSA:3.10.290.10 2 62 8.6E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 SMART SM00363 7 67 1.2E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 SUPERFAMILY SSF55120 54 245 1.33E-44 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 Gene3D G3DSA:3.30.70.580 63 152 4.1E-20 T 29-03-2018 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 109 123 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 Gene3D G3DSA:3.30.70.1560 153 221 3.7E-19 T 29-03-2018 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 SUPERFAMILY SSF55174 3 60 7.85E-15 T 29-03-2018 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 234 2.2E-46 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 Pfam PF00849 RNA pseudouridylate synthase 69 204 9.4E-21 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS11760 6915c30b7bc14210867499fd00c5fa6f 247 Pfam PF01479 S4 domain 8 51 1.3E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 Gene3D G3DSA:4.10.520.10 1 97 2.8E-27 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 SUPERFAMILY SSF47729 2 93 8.54E-27 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 SMART SM00411 2 91 2.5E-37 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.2E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.2E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.2E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 Pfam PF00216 Bacterial DNA-binding protein 2 90 3.5E-26 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MSG_RS07840 ec5f2df35deef822d86e812e424a6dc9 215 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MSG_RS12830 c13a262b28351b107d1dd108e7864cba 251 Gene3D G3DSA:1.10.1660.10 4 133 4.1E-18 T 29-03-2018 MSG_RS12830 c13a262b28351b107d1dd108e7864cba 251 SUPERFAMILY SSF46955 27 92 5.04E-12 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS12830 c13a262b28351b107d1dd108e7864cba 251 SMART SM00422 12 86 1.1E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS12830 c13a262b28351b107d1dd108e7864cba 251 Pfam PF00376 MerR family regulatory protein 24 54 9.8E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS12830 c13a262b28351b107d1dd108e7864cba 251 Gene3D G3DSA:1.10.1660.10 134 240 0.25 T 29-03-2018 MSG_RS18570 63856cfffb454d5f53550cbca9a932b9 379 SUPERFAMILY SSF55073 212 374 1.32E-32 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS18570 63856cfffb454d5f53550cbca9a932b9 379 Pfam PF16701 Adenylate cyclase regulatory domain 11 193 1.0E-84 T 29-03-2018 IPR032026 Adenylate cyclase regulatory domain MSG_RS18570 63856cfffb454d5f53550cbca9a932b9 379 SMART SM00044 168 352 3.3E-5 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18570 63856cfffb454d5f53550cbca9a932b9 379 Gene3D G3DSA:3.30.70.1230 194 372 8.9E-28 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18570 63856cfffb454d5f53550cbca9a932b9 379 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 212 366 2.8E-11 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 76 88 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 Gene3D G3DSA:3.40.190.80 125 242 8.8E-24 T 29-03-2018 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 SUPERFAMILY SSF56655 2 239 1.3E-50 T 29-03-2018 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 Pfam PF00459 Inositol monophosphatase family 7 226 1.6E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 PRINTS PR00377 Inositol monophosphatase superfamily signature 54 70 1.5E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 1.5E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 PRINTS PR00377 Inositol monophosphatase superfamily signature 187 211 1.5E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 PRINTS PR00377 Inositol monophosphatase superfamily signature 155 176 1.5E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS16085 d068ddaab726459176a1ced708c91df7 242 Gene3D G3DSA:3.30.540.10 2 124 2.1E-24 T 29-03-2018 MSG_RS03720 feea376faff7066d93cdd37793e3e17f 124 Pfam PF14012 Protein of unknown function (DUF4229) 27 93 4.4E-19 T 29-03-2018 IPR025323 Protein of unknown function DUF4229 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Gene3D G3DSA:3.40.50.1380 1 197 4.0E-66 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 SMART SM00798 140 457 1.0E-181 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 SUPERFAMILY SSF53927 217 526 7.72E-112 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Pfam PF01808 AICARFT/IMPCHase bienzyme 140 456 1.2E-110 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 SMART SM00851 21 135 2.6E-47 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 PIRSF PIRSF000414 3 526 4.5E-188 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Gene3D G3DSA:3.40.140.20 369 516 2.4E-48 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Gene3D G3DSA:3.40.140.20 230 367 8.3E-47 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 9 526 41.591 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 526 1.0E-164 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 SUPERFAMILY SSF52335 9 197 1.3E-61 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS20315 5b2a0b58226ab03c585edc6c74674f1f 526 Pfam PF02142 MGS-like domain 21 134 8.9E-24 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS12320 094f84fe89ffd6ea1cd4eb759af51fcd 138 SUPERFAMILY SSF50249 4 128 1.7E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS12320 094f84fe89ffd6ea1cd4eb759af51fcd 138 Gene3D G3DSA:2.40.50.140 62 126 1.5E-19 T 29-03-2018 MSG_RS12320 094f84fe89ffd6ea1cd4eb759af51fcd 138 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 21 57 5.5E-6 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS12320 094f84fe89ffd6ea1cd4eb759af51fcd 138 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 122 4.8E-20 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 16 468 45.988 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 17 469 5.9E-164 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Gene3D G3DSA:3.60.20.10 3 170 2.0E-37 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Gene3D G3DSA:3.60.20.10 171 246 1.2E-22 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 SUPERFAMILY SSF56235 17 275 3.86E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Pfam PF00156 Phosphoribosyl transferase domain 283 393 1.3E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Pfam PF13522 Glutamine amidotransferase domain 75 217 8.3E-15 T 29-03-2018 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 PIRSF PIRSF000485 13 484 2.2E-158 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 Gene3D G3DSA:3.40.50.2020 247 454 1.6E-31 T 29-03-2018 MSG_RS21770 b75d47c8bee26da4c5c8f842646c31d4 514 SUPERFAMILY SSF53271 258 478 4.06E-65 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 Gene3D G3DSA:2.60.120.260 352 557 2.6E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 SUPERFAMILY SSF53474 23 330 4.83E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 SUPERFAMILY SSF49785 351 559 1.49E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 Gene3D G3DSA:3.40.50.1820 34 351 7.7E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 336 516 3.0E-18 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 51 559 5.8E-129 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 SMART SM00939 321 554 1.1E-33 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MSG_RS18835 cdcec43396771a3c21958c5b603a56b5 564 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 305 3.2E-40 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MSG_RS10760 3e710186a2f4c72c764db60b361298b4 422 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 92 3.8E-10 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS10760 3e710186a2f4c72c764db60b361298b4 422 SUPERFAMILY SSF53756 1 419 2.42E-94 T 29-03-2018 MSG_RS10760 3e710186a2f4c72c764db60b361298b4 422 Gene3D G3DSA:3.40.50.2000 258 400 5.4E-25 T 29-03-2018 MSG_RS10760 3e710186a2f4c72c764db60b361298b4 422 Gene3D G3DSA:3.40.50.2000 1 257 1.6E-38 T 29-03-2018 MSG_RS16170 2b95d979cac004bcd38611f4667e053c 228 SUPERFAMILY SSF53254 29 218 1.77E-32 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS16170 2b95d979cac004bcd38611f4667e053c 228 Gene3D G3DSA:3.40.50.1240 27 225 1.3E-34 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS16170 2b95d979cac004bcd38611f4667e053c 228 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 32 41 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MSG_RS16170 2b95d979cac004bcd38611f4667e053c 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 30 222 2.0E-30 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS16170 2b95d979cac004bcd38611f4667e053c 228 SMART SM00855 29 182 3.8E-15 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 Gene3D G3DSA:3.30.1130.10 1 119 3.7E-36 T 29-03-2018 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 3.2E-40 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 TIGRFAM TIGR00526 folB_dom: FolB domain 2 120 3.4E-36 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 SMART SM00905 5 117 7.5E-48 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 Pfam PF02152 Dihydroneopterin aldolase 5 116 7.4E-33 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MSG_RS22850 0e3570c438c6403b580eb65ddd714731 132 SUPERFAMILY SSF55620 3 119 2.06E-36 T 29-03-2018 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 Gene3D G3DSA:3.40.190.10 176 262 1.1E-13 T 29-03-2018 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 SUPERFAMILY SSF46785 10 92 1.04E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 Gene3D G3DSA:3.40.190.10 92 175 3.7E-10 T 29-03-2018 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 SUPERFAMILY SSF53850 95 289 9.46E-24 T 29-03-2018 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 Pfam PF03466 LysR substrate binding domain 95 285 5.4E-23 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 7.7E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS13360 6f75196f2b6393d5c76ce4e9ffce9952 291 Gene3D G3DSA:1.10.10.10 6 91 2.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08755 2feac2d5d770ed9cc5ac820308f6df67 249 Gene3D G3DSA:3.40.50.1820 5 244 2.9E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08755 2feac2d5d770ed9cc5ac820308f6df67 249 Pfam PF01738 Dienelactone hydrolase family 24 244 2.5E-55 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MSG_RS08755 2feac2d5d770ed9cc5ac820308f6df67 249 SUPERFAMILY SSF53474 6 243 5.36E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15795 87b26102568986e197ffafc8e4972e20 273 SUPERFAMILY SSF56601 10 267 5.8E-49 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS15795 87b26102568986e197ffafc8e4972e20 273 Gene3D G3DSA:3.40.710.10 2 271 2.1E-48 T 29-03-2018 MSG_RS15795 87b26102568986e197ffafc8e4972e20 273 Pfam PF00144 Beta-lactamase 31 255 4.1E-33 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 219 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 238 2.3E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 1.8E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 1.8E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 200 219 1.8E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 SUPERFAMILY SSF51735 134 276 6.39E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 SUPERFAMILY SSF51735 1 106 6.39E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 Gene3D G3DSA:3.40.50.720 183 283 3.0E-11 T 29-03-2018 MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 Pfam PF00106 short chain dehydrogenase 9 231 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06665 d36932a7950c078b631f63f71a15f9ae 291 Gene3D G3DSA:3.40.50.720 1 182 9.2E-37 T 29-03-2018 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Gene3D G3DSA:3.30.450.20 153 296 0.0015 T 29-03-2018 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SUPERFAMILY SSF158472 219 266 1.27E-5 T 29-03-2018 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Pfam PF05227 CHASE3 domain 50 174 1.6E-24 T 29-03-2018 IPR007891 CHASE3 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SUPERFAMILY SSF55874 349 514 1.83E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 513 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 457 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 494 2.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SMART SM00388 292 360 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 514 1.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Pfam PF00512 His Kinase A (phospho-acceptor) domain 293 357 2.5E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Gene3D G3DSA:1.10.287.130 297 356 2.2E-12 T 29-03-2018 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SMART SM00387 402 516 5.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SMART SM00304 217 270 1.8E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 Gene3D G3DSA:3.30.565.10 362 525 1.1E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05745 0b4cfcb7dac47b70484c1ef642f26c2b 531 SUPERFAMILY SSF47384 279 358 8.83E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 Pfam PF09084 NMT1/THI5 like 84 259 4.1E-16 T 29-03-2018 IPR015168 SsuA/THI5-like MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 SUPERFAMILY SSF53850 64 273 8.65E-41 T 29-03-2018 MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 47 324 8.5E-54 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 Gene3D G3DSA:3.40.190.10 141 329 3.7E-34 T 29-03-2018 MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 Gene3D G3DSA:3.40.190.10 42 140 3.3E-8 T 29-03-2018 MSG_RS20900 cd727dfc492c3310918adf93bd5a1275 334 SMART SM00062 45 256 1.1E-6 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 ProSitePatterns PS00885 EPSP synthase signature 2. 345 363 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 424 5.1E-111 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 22 429 1.4E-102 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 17 432 28.787 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 Gene3D G3DSA:3.65.10.10 29 235 5.9E-52 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 ProSitePatterns PS00104 EPSP synthase signature 1. 96 110 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 Gene3D G3DSA:3.65.10.10 236 431 1.8E-44 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 SUPERFAMILY SSF55205 16 429 4.91E-91 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MSG_RS06065 41acdbfbf1b88d18b599981be82df178 454 PIRSF PIRSF000505 7 434 1.3E-116 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 Gene3D G3DSA:1.10.10.60 1 62 4.7E-20 T 29-03-2018 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 SUPERFAMILY SSF46689 6 88 1.15E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 SUPERFAMILY SSF48498 86 177 2.11E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 Gene3D G3DSA:1.10.357.10 63 202 4.8E-21 T 29-03-2018 MSG_RS17475 0fdce5094641280ea53767a96ad70530 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 8.1E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 PRINTS PR00990 Ribokinase signature 6 27 2.1E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 PRINTS PR00990 Ribokinase signature 174 189 2.1E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 PRINTS PR00990 Ribokinase signature 33 52 2.1E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 PRINTS PR00990 Ribokinase signature 104 117 2.1E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 PRINTS PR00990 Ribokinase signature 199 210 2.1E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 Hamap MF_01987 Ribokinase [rbsK]. 2 287 22.163 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MSG_RS17050 473f67d0d454987079cfed257c53f942 292 Gene3D G3DSA:3.40.1190.20 1 292 6.7E-63 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS17050 473f67d0d454987079cfed257c53f942 292 SUPERFAMILY SSF53613 1 285 1.04E-60 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS17050 473f67d0d454987079cfed257c53f942 292 Pfam PF00294 pfkB family carbohydrate kinase 1 279 1.2E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 SUPERFAMILY SSF52374 11 323 1.42E-97 T 29-03-2018 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 SUPERFAMILY SSF48163 324 488 7.72E-36 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Gene3D G3DSA:3.40.50.620 11 135 1.8E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Gene3D G3DSA:1.10.10.350 392 491 7.1E-26 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 1.1E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 1.1E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 1.1E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 1.1E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 1.1E-22 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 327 3.0E-78 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 10 488 30.773 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 11 485 8.9E-130 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Gene3D G3DSA:1.10.1160.10 256 339 2.3E-27 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MSG_RS07805 291e7ffb1bd29db9c03e165a6bfd0fe3 492 Gene3D G3DSA:3.40.50.620 136 255 2.0E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 Gene3D G3DSA:3.10.290.10 1 64 8.0E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 Pfam PF01728 FtsJ-like methyltransferase 62 243 2.1E-22 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 SUPERFAMILY SSF55174 4 62 1.91E-9 T 29-03-2018 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 1.0E-60 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 SUPERFAMILY SSF53335 62 244 6.23E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 Pfam PF01479 S4 domain 6 46 2.6E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 Gene3D G3DSA:3.40.50.150 65 276 1.5E-53 T 29-03-2018 MSG_RS11695 3481837ab8c47e54c0c8d46fbb2af4a5 326 SMART SM00363 5 68 2.1E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 Hamap MF_01694 Biotin synthase [bioB]. 35 343 38.277 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 250 338 1.3E-11 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 SMART SM00876 250 342 3.4E-28 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 SUPERFAMILY SSF102114 34 334 2.62E-66 T 29-03-2018 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 PIRSF PIRSF001619 18 348 5.4E-107 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 Gene3D G3DSA:3.20.20.70 25 333 1.0E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 Pfam PF04055 Radical SAM superfamily 82 239 2.2E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 TIGRFAM TIGR00433 bioB: biotin synthase 47 340 9.6E-107 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MSG_RS11105 cc64ea5a6e60ce7d0640c69fea064b40 349 SMART SM00729 75 279 1.1E-35 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS17700 66ab71887202e7621980958639be71fc 63 Gene3D G3DSA:3.30.70.20 1 63 1.2E-7 T 29-03-2018 MSG_RS17700 66ab71887202e7621980958639be71fc 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 2.6E-11 T 29-03-2018 MSG_RS17700 66ab71887202e7621980958639be71fc 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 7.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS17700 66ab71887202e7621980958639be71fc 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 7.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS17700 66ab71887202e7621980958639be71fc 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 7.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS17700 66ab71887202e7621980958639be71fc 63 SUPERFAMILY SSF54862 2 61 1.71E-10 T 29-03-2018 MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 Gene3D G3DSA:3.40.50.720 5 305 6.7E-57 T 29-03-2018 MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 Pfam PF00106 short chain dehydrogenase 19 221 1.1E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 SUPERFAMILY SSF51735 16 279 1.73E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 218 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03165 72bb51c79942df78e1cbd51713537dc8 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 199 2.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 244 1.8E-38 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 190 206 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 56 64 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 250 31.67 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 Pfam PF01261 Xylose isomerase-like TIM barrel 13 214 4.6E-34 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 SMART SM00518 2 250 4.2E-86 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 Gene3D G3DSA:3.20.20.150 1 252 1.5E-45 T 29-03-2018 MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 SUPERFAMILY SSF51658 2 249 2.88E-61 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS04240 b5b38ee583093d6b5610fb498359c03c 252 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 158 165 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Pfam PF04542 Sigma-70 region 2 44 112 8.4E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Gene3D G3DSA:1.10.601.10 21 111 4.8E-17 T 29-03-2018 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Pfam PF04545 Sigma-70, region 4 212 261 1.4E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 SUPERFAMILY SSF88659 116 183 3.27E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 SUPERFAMILY SSF88659 181 263 2.43E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 PRINTS PR00046 Major sigma-70 factor signature 233 248 4.8E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 PRINTS PR00046 Major sigma-70 factor signature 67 80 4.8E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 PRINTS PR00046 Major sigma-70 factor signature 248 259 4.8E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 PRINTS PR00046 Major sigma-70 factor signature 216 228 4.8E-9 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 263 5.1E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Pfam PF04539 Sigma-70 region 3 126 185 1.2E-10 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Gene3D G3DSA:1.10.10.10 179 264 7.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 263 6.7E-92 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 Gene3D G3DSA:1.10.10.10 113 165 2.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05665 fda6384b476ff7d391480288bd39187e 264 SUPERFAMILY SSF88946 12 112 5.18E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 6.6E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 3.7E-54 T 29-03-2018 MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 SUPERFAMILY SSF51735 6 242 7.81E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 Gene3D G3DSA:3.40.50.720 1 48 8.0E-10 T 29-03-2018 MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 Gene3D G3DSA:3.40.50.720 49 246 6.2E-54 T 29-03-2018 MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11950 2fe76c18f7b2ca935172da00045ccbc3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 5.3E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18105 24467131a984091b68bf98431336b733 438 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 425 4.4E-133 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 MSG_RS18105 24467131a984091b68bf98431336b733 438 SUPERFAMILY SSF54675 6 134 4.36E-37 T 29-03-2018 MSG_RS18105 24467131a984091b68bf98431336b733 438 Gene3D G3DSA:3.20.140.10 1 371 8.9E-93 T 29-03-2018 MSG_RS18105 24467131a984091b68bf98431336b733 438 PIRSF PIRSF000484 2 430 1.9E-98 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MSG_RS18105 24467131a984091b68bf98431336b733 438 SUPERFAMILY SSF51690 136 433 2.21E-76 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MSG_RS22235 b3cbec394796fce26fdbbb9fe06b16b0 493 Pfam PF00982 Glycosyltransferase family 20 18 484 2.3E-160 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 MSG_RS22235 b3cbec394796fce26fdbbb9fe06b16b0 493 Gene3D G3DSA:3.40.50.2000 278 470 4.7E-43 T 29-03-2018 MSG_RS22235 b3cbec394796fce26fdbbb9fe06b16b0 493 Gene3D G3DSA:3.40.50.2000 15 277 1.4E-88 T 29-03-2018 MSG_RS22235 b3cbec394796fce26fdbbb9fe06b16b0 493 SUPERFAMILY SSF53756 17 487 4.83E-143 T 29-03-2018 MSG_RS01860 2e657db26dfe19bf28b964185ef80855 96 Pfam PF02583 Metal-sensitive transcriptional repressor 11 91 4.0E-31 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 Gene3D G3DSA:3.40.50.10090 324 366 7.8E-8 T 29-03-2018 MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 SUPERFAMILY SSF51735 325 562 1.43E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 Pfam PF00106 short chain dehydrogenase 328 515 7.9E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 327 344 9.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 449 465 9.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 475 494 9.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 401 412 9.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 496 513 9.8E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 Gene3D G3DSA:3.40.50.1820 1 303 4.3E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 455 463 5.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 401 412 5.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 475 494 5.0E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 Gene3D G3DSA:3.40.50.720 367 563 1.5E-49 T 29-03-2018 MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 SUPERFAMILY SSF53474 9 299 1.1E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 Pfam PF00561 alpha/beta hydrolase fold 31 287 2.5E-30 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS15415 6a2c372ce7a7d9e6872b0256f9526948 594 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 462 490 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS14830 f130830636b6086c18c53b2b3af7c254 287 Pfam PF02405 Permease MlaE 71 274 2.0E-53 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS12015 6860e80ebe6af39255c0cb249a16fc63 346 SUPERFAMILY SSF53850 44 341 3.09E-53 T 29-03-2018 MSG_RS12015 6860e80ebe6af39255c0cb249a16fc63 346 Gene3D G3DSA:3.40.190.10 146 343 1.6E-37 T 29-03-2018 MSG_RS12015 6860e80ebe6af39255c0cb249a16fc63 346 Gene3D G3DSA:3.40.190.10 12 145 2.3E-16 T 29-03-2018 MSG_RS12015 6860e80ebe6af39255c0cb249a16fc63 346 Pfam PF13531 Bacterial extracellular solute-binding protein 49 293 2.6E-31 T 29-03-2018 MSG_RS12015 6860e80ebe6af39255c0cb249a16fc63 346 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 61 331 3.9E-52 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MSG_RS07240 f6321a907c2be389ca2873d70cc92f2c 131 Pfam PF11964 SpoIIAA-like 14 121 7.5E-16 T 29-03-2018 IPR021866 SpoIIAA-like MSG_RS07240 f6321a907c2be389ca2873d70cc92f2c 131 Gene3D G3DSA:3.40.50.10600 1 123 3.2E-13 T 29-03-2018 MSG_RS07240 f6321a907c2be389ca2873d70cc92f2c 131 SUPERFAMILY SSF52091 2 121 1.57E-28 T 29-03-2018 IPR002645 STAS domain MSG_RS10855 328ccf4bb2029c1bde8f41de2bcf22d0 262 PIRSF PIRSF006648 1 259 2.1E-62 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS10855 328ccf4bb2029c1bde8f41de2bcf22d0 262 Pfam PF12698 ABC-2 family transporter protein 62 246 6.4E-13 T 29-03-2018 MSG_RS10855 328ccf4bb2029c1bde8f41de2bcf22d0 262 TIGRFAM TIGR01248 drrC: daunorubicin resistance protein C 75 226 6.1E-58 T 29-03-2018 IPR005943 Daunorubicin resistance protein C MSG_RS20195 7788b9aeba922faccd2fd30e27edd0e6 303 Pfam PF00483 Nucleotidyl transferase 13 277 6.0E-28 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MSG_RS20195 7788b9aeba922faccd2fd30e27edd0e6 303 SUPERFAMILY SSF53448 12 290 5.18E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS20195 7788b9aeba922faccd2fd30e27edd0e6 303 Gene3D G3DSA:3.90.550.10 7 287 2.5E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 SUPERFAMILY SSF55920 145 372 1.31E-71 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 146 1.3E-9 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 Pfam PF00557 Metallopeptidase family M24 154 356 5.5E-61 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 302 314 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 SUPERFAMILY SSF53092 5 144 9.94E-14 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 Gene3D G3DSA:3.90.230.10 132 365 1.2E-70 T 29-03-2018 MSG_RS14700 422f1d9e3289c2ca5a833e82df3414d3 375 Gene3D G3DSA:3.40.350.10 1 131 4.1E-15 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MSG_RS10170 4df07f2f8a78205bd2501e243eb02a36 292 SUPERFAMILY SSF161098 89 268 2.75E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS10170 4df07f2f8a78205bd2501e243eb02a36 292 Gene3D G3DSA:1.10.3720.10 26 285 2.1E-22 T 29-03-2018 MSG_RS10170 4df07f2f8a78205bd2501e243eb02a36 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 281 5.7E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS11220 110aa15838f37b041c7b532e22eb2485 226 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 16 211 5.0E-45 T 29-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp MSG_RS11220 110aa15838f37b041c7b532e22eb2485 226 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 9 211 5.4E-64 T 29-03-2018 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 Gene3D G3DSA:1.10.630.10 6 403 3.7E-63 T 29-03-2018 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00385 P450 superfamily signature 346 355 1.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00385 P450 superfamily signature 279 290 1.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00385 P450 superfamily signature 355 366 1.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00385 P450 superfamily signature 244 261 1.8E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 355 366 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 279 290 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 324 339 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 139 155 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 156 171 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 199 221 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 346 355 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 93 104 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 PRINTS PR00359 B-class P450 signature 296 323 7.1E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 SUPERFAMILY SSF48264 8 402 1.3E-79 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS00065 231bd8288f7ad2aa1674b367716a457e 404 Pfam PF00067 Cytochrome P450 228 379 2.5E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16885 4d726869929921956f84d73d04e4bb17 296 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 40 290 9.8E-80 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MSG_RS16885 4d726869929921956f84d73d04e4bb17 296 SUPERFAMILY SSF161098 42 282 1.44E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16885 4d726869929921956f84d73d04e4bb17 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 290 2.2E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16885 4d726869929921956f84d73d04e4bb17 296 Gene3D G3DSA:1.10.3720.10 38 294 5.3E-43 T 29-03-2018 MSG_RS16885 4d726869929921956f84d73d04e4bb17 296 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 39 286 4.2E-75 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 Gene3D G3DSA:3.90.930.12 84 179 2.0E-38 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.39 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 Gene3D G3DSA:3.90.930.12 2 83 5.6E-28 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 PIRSF PIRSF002162 1 178 3.2E-49 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 Pfam PF00347 Ribosomal protein L6 11 83 1.9E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 Pfam PF00347 Ribosomal protein L6 91 165 9.9E-22 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 7.5E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 7.5E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 7.5E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 SUPERFAMILY SSF56053 84 178 3.8E-35 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 SUPERFAMILY SSF56053 1 83 2.62E-25 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04580 26ad854ce75e919a8a305a19b03e7bc7 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 4.6E-73 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 Gene3D G3DSA:3.30.540.10 2 147 1.4E-42 T 29-03-2018 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 Pfam PF00459 Inositol monophosphatase family 11 255 1.9E-46 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 Gene3D G3DSA:3.40.190.80 148 259 7.6E-23 T 29-03-2018 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 SUPERFAMILY SSF56655 3 257 3.93E-74 T 29-03-2018 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 6 257 2.9E-86 T 29-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.8E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.8E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 2.8E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS06845 8b7125b72cc079c6bd95304bb3383f78 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.8E-18 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 1.4E-124 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 SMART SM00865 204 321 8.3E-54 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 Gene3D G3DSA:3.40.50.1440 5 211 3.5E-40 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 5.6E-39 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.8E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.8E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.8E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.8E-50 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 SUPERFAMILY SSF55307 201 314 4.58E-42 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 346 37.956 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 SMART SM00864 10 202 1.6E-106 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.3E-34 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 Gene3D G3DSA:3.30.1330.20 212 319 6.4E-44 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MSG_RS15075 8eaa0402aa5248dc8785195d9415b03b 387 SUPERFAMILY SSF52490 9 205 1.31E-66 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MSG_RS04255 ee82693636da8e5e56c12f327063cf0d 240 Gene3D G3DSA:1.10.10.10 1 74 0.0024 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04255 ee82693636da8e5e56c12f327063cf0d 240 Pfam PF07848 PaaX-like protein 6 66 1.8E-16 T 29-03-2018 IPR012906 PaaX-like, N-terminal MSG_RS04255 ee82693636da8e5e56c12f327063cf0d 240 Pfam PF08223 PaaX-like protein C-terminal domain 194 229 1.2E-6 T 29-03-2018 IPR013225 PaaX-like, C-terminal MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Pfam PF02779 Transketolase, pyrimidine binding domain 374 555 2.3E-43 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Gene3D G3DSA:3.40.50.920 568 693 6.9E-30 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 SUPERFAMILY SSF52518 8 344 2.24E-96 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 SUPERFAMILY SSF52922 562 695 2.49E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 TIGRFAM TIGR00232 tktlase_bact: transketolase 26 694 1.1E-232 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Gene3D G3DSA:3.40.50.970 13 371 9.3E-83 T 29-03-2018 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 SUPERFAMILY SSF52518 357 557 3.91E-61 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 SMART SM00861 375 557 4.4E-60 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Pfam PF02780 Transketolase, C-terminal domain 579 686 3.9E-13 T 29-03-2018 IPR033248 Transketolase, C-terminal domain MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 2.3E-141 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS10515 e5f2a87e51c5c359d8f15c6663e9b7f0 696 Gene3D G3DSA:3.40.50.970 372 564 3.5E-42 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF51735 1190 1399 1.08E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1412 1588 2.1E-36 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF00550 Phosphopantetheine attachment site 1681 1747 1.3E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.10.129.10 898 1027 2.7E-14 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.366.10 559 694 6.6E-35 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.50.720 1156 1384 0.006 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.47.10 300 457 1.2E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SMART SM00826 901 1063 2.5E-43 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.47.10 29 297 5.8E-89 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF51735 1410 1642 6.93E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF08659 KR domain 1412 1587 2.7E-54 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF53901 35 406 1.5E-96 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SMART SM00823 Phosphopantetheine attachment site 1680 1752 1.6E-19 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF55048 683 747 1.11E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF14765 Polyketide synthase dehydratase 901 1184 7.7E-64 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF00698 Acyl transferase domain 561 862 6.7E-95 T 29-03-2018 IPR014043 Acyl transferase MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 850 2.7E-93 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SMART SM00825 Beta-ketoacyl synthase 38 459 1.4E-207 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1707 1722 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 523 7.5E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.50.720 1404 1651 7.4E-40 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.40.366.10 741 857 8.4E-21 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 407 8.9E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 285 3.6E-96 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF52151 560 685 4.19E-58 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF52151 748 843 4.19E-58 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:1.10.1200.10 1673 1787 2.0E-15 T 29-03-2018 MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 SUPERFAMILY SSF47336 1676 1764 2.49E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08045 b8a63d659a6d7e274cab5cb69ecf6c81 1788 Gene3D G3DSA:3.30.70.250 695 740 1.8E-13 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 586 602 8.8E-50 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 663 682 8.8E-50 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 716 734 8.8E-50 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 693 712 8.8E-50 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 350 369 8.8E-50 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 666 674 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 SUPERFAMILY SSF88697 7 186 1.32E-17 T 29-03-2018 IPR015947 PUA-like domain MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 SMART SM00382 342 486 6.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Hamap MF_01973 Lon protease [lon]. 7 762 60.691 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 186 6.8E-13 T 29-03-2018 IPR003111 Lon, substrate-binding domain MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 SUPERFAMILY SSF54211 586 759 1.06E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 PIRSF PIRSF001174 1 765 1.8E-250 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 346 482 3.2E-20 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Gene3D G3DSA:3.40.50.300 298 485 6.3E-29 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Gene3D G3DSA:3.30.230.10 576 762 1.2E-60 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Gene3D G3DSA:1.10.8.60 486 575 7.1E-25 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 SUPERFAMILY SSF52540 292 566 3.13E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 TIGRFAM TIGR00763 lon: endopeptidase La 9 760 3.8E-243 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Gene3D G3DSA:1.10.4060.10 108 196 1.6E-6 T 29-03-2018 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 561 762 1.2E-84 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 SMART SM00464 6 189 5.3E-33 T 29-03-2018 IPR003111 Lon, substrate-binding domain MSG_RS13075 6056cf83cf6f30dd11015301836861c6 772 Gene3D G3DSA:2.30.130.40 1 107 1.7E-10 T 29-03-2018 MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 SUPERFAMILY SSF56349 8 291 5.3E-49 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 Pfam PF00589 Phage integrase family 109 283 2.4E-44 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 Gene3D G3DSA:1.10.443.10 109 292 7.0E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 54.13 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 Gene3D G3DSA:1.10.150.130 1 108 2.3E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MSG_RS08300 96e9829e0352a594a521d1f9b3f3069a 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 3.0E-17 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 SUPERFAMILY SSF53244 333 482 1.52E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 426 1.6E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Gene3D G3DSA:3.40.50.720 2 103 1.6E-13 T 29-03-2018 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Gene3D G3DSA:3.40.1190.10 112 334 6.8E-43 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 485 38.166 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Gene3D G3DSA:3.90.190.20 335 485 7.7E-38 T 29-03-2018 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Pfam PF01225 Mur ligase family, catalytic domain 13 115 5.3E-23 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 SUPERFAMILY SSF53623 101 332 7.85E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 Pfam PF08245 Mur ligase middle domain 120 314 6.4E-24 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 SUPERFAMILY SSF51984 11 102 8.76E-20 T 29-03-2018 MSG_RS15085 77b69096144863b251b50f76d1f6ad99 499 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 479 2.9E-150 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 115 1.6E-35 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 3.5E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 SUPERFAMILY SSF47203 228 378 5.64E-49 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Gene3D G3DSA:1.20.140.10 219 379 4.1E-53 T 29-03-2018 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 SUPERFAMILY SSF56645 2 243 7.2E-75 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Gene3D G3DSA:1.10.540.10 1 118 1.7E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 217 6.1E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17460 34d05bf057c4d4e5d179e199ab1f914f 381 Gene3D G3DSA:2.40.110.10 119 218 2.0E-30 T 29-03-2018 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1061 1077 6.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1047 1061 6.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1077 1089 6.4E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SUPERFAMILY SSF46894 1039 1104 1.09E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Gene3D G3DSA:1.25.40.10 550 1036 9.4E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Gene3D G3DSA:3.40.50.300 201 354 2.3E-14 T 29-03-2018 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SMART SM00421 1044 1101 4.6E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 28 158 3.1E-9 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Pfam PF00196 Bacterial regulatory proteins, luxR family 1046 1099 4.0E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SUPERFAMILY SSF55073 22 201 2.35E-38 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SUPERFAMILY SSF52540 207 470 4.53E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Gene3D G3DSA:1.10.10.10 1037 1105 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00364 Disease resistance protein signature 238 253 8.4E-7 T 29-03-2018 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00364 Disease resistance protein signature 402 416 8.4E-7 T 29-03-2018 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 PRINTS PR00364 Disease resistance protein signature 307 321 8.4E-7 T 29-03-2018 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 Gene3D G3DSA:3.30.70.1230 28 196 9.1E-28 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SUPERFAMILY SSF48452 909 963 8.26E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SUPERFAMILY SSF48452 764 868 8.26E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 SMART SM00044 2 169 0.0011 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS03635 4962de417b9a82672209a0517f39cc0f 1105 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1061 1088 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 128 144 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 344 355 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 82 93 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 145 160 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 314 329 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 188 210 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 269 280 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 335 344 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 PRINTS PR00359 B-class P450 signature 286 313 6.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 Pfam PF00067 Cytochrome P450 176 364 2.3E-28 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 SUPERFAMILY SSF48264 22 397 6.68E-88 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS22375 c730c63048b4860a7e53e7b3742fdca3 402 Gene3D G3DSA:1.10.630.10 12 396 1.7E-72 T 29-03-2018 MSG_RS23775 12829f425b79405c88634c93d95c4929 298 Gene3D G3DSA:3.40.50.720 1 167 8.3E-18 T 29-03-2018 MSG_RS23775 12829f425b79405c88634c93d95c4929 298 SUPERFAMILY SSF51735 1 286 2.42E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23775 12829f425b79405c88634c93d95c4929 298 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 1.8E-11 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS23775 12829f425b79405c88634c93d95c4929 298 Gene3D G3DSA:3.90.25.10 168 292 7.1E-11 T 29-03-2018 MSG_RS04145 00a8c3d407fad2ab87271a6b9150ca6e 286 Gene3D G3DSA:3.40.50.150 2 286 2.5E-49 T 29-03-2018 MSG_RS04145 00a8c3d407fad2ab87271a6b9150ca6e 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 282 1.9E-106 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04145 00a8c3d407fad2ab87271a6b9150ca6e 286 PIRSF PIRSF003085 5 286 5.7E-91 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS04145 00a8c3d407fad2ab87271a6b9150ca6e 286 SUPERFAMILY SSF53335 12 286 1.02E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 Pfam PF01649 Ribosomal protein S20 2 84 1.4E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 SUPERFAMILY SSF46992 3 86 1.22E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.3E-25 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 Gene3D G3DSA:1.20.58.110 1 86 9.4E-29 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.225 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16950 36953edc3c8a1945b10d65790e432238 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 1.0E-24 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS23520 31de94bed54e0ccb755a692ed9a2965a 365 Pfam PF14031 Putative serine dehydratase domain 251 347 5.0E-18 T 29-03-2018 IPR026956 D-serine dehydratase-like domain MSG_RS23520 31de94bed54e0ccb755a692ed9a2965a 365 SUPERFAMILY SSF51419 16 241 1.09E-39 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS23520 31de94bed54e0ccb755a692ed9a2965a 365 Gene3D G3DSA:3.20.20.10 3 245 6.9E-49 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS23520 31de94bed54e0ccb755a692ed9a2965a 365 Pfam PF01168 Alanine racemase, N-terminal domain 15 237 4.5E-34 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MSG_RS23520 31de94bed54e0ccb755a692ed9a2965a 365 SMART SM01119 251 348 9.0E-35 T 29-03-2018 IPR026956 D-serine dehydratase-like domain MSG_RS00445 1b6a232dbd5687175dc1a369f7e18b58 142 SUPERFAMILY SSF46689 48 98 5.38E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00445 1b6a232dbd5687175dc1a369f7e18b58 142 Pfam PF01527 Transposase 48 99 1.1E-9 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MSG_RS00445 1b6a232dbd5687175dc1a369f7e18b58 142 Gene3D G3DSA:1.10.10.60 60 100 8.3E-4 T 29-03-2018 MSG_RS00445 1b6a232dbd5687175dc1a369f7e18b58 142 Gene3D G3DSA:1.10.10.60 20 59 0.002 T 29-03-2018 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 Gene3D G3DSA:3.40.50.10490 5 260 6.0E-99 T 29-03-2018 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 SUPERFAMILY SSF52313 6 229 8.76E-95 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 158 175 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 175 186 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 PRINTS PR00395 Ribosomal protein S2 signature 196 210 4.4E-39 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.7E-111 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 233 42.437 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08310 3d1a6e3f559744e4b33987efc7ec94f5 281 Pfam PF00318 Ribosomal protein S2 9 224 2.8E-97 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS11815 3383bada8a4fe13173ed1a79f4882cf8 328 SUPERFAMILY SSF47240 2 299 5.35E-83 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS11815 3383bada8a4fe13173ed1a79f4882cf8 328 PIRSF PIRSF000346 1 318 1.6E-106 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS11815 3383bada8a4fe13173ed1a79f4882cf8 328 Pfam PF03405 Fatty acid desaturase 1 311 7.7E-88 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS11815 3383bada8a4fe13173ed1a79f4882cf8 328 Gene3D G3DSA:1.10.620.20 1 317 3.0E-93 T 29-03-2018 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 362 7.8E-178 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 ProSitePatterns PS00958 Transaldolase active site. 139 156 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 Gene3D G3DSA:3.20.20.70 3 364 5.4E-131 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 Hamap MF_00493 Transaldolase [tal]. 1 372 165.046 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 PIRSF PIRSF036915 1 372 4.4E-178 T 29-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 SUPERFAMILY SSF51569 10 362 1.01E-78 T 29-03-2018 MSG_RS10510 d529dfdda775cf40b2a606c5ff19d52a 372 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 362 3.3E-84 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 Pfam PF13416 Bacterial extracellular solute-binding protein 67 324 1.1E-27 T 29-03-2018 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 SUPERFAMILY SSF53850 46 369 3.16E-62 T 29-03-2018 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 188 207 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 52 68 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 170 184 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 68 89 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 144 160 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 110 123 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 271 290 1.0E-23 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 Gene3D G3DSA:3.40.190.10 169 310 7.0E-27 T 29-03-2018 MSG_RS10090 4e0fd617e315b5de8251e36f96343673 372 Gene3D G3DSA:3.40.190.10 46 168 5.2E-14 T 29-03-2018 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 Pfam PF01227 GTP cyclohydrolase I 22 199 9.4E-76 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 200 41.756 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 Gene3D G3DSA:3.30.1130.10 68 202 3.7E-57 T 29-03-2018 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 Gene3D G3DSA:1.10.286.10 19 67 4.9E-23 T 29-03-2018 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 SUPERFAMILY SSF55620 14 199 2.08E-76 T 29-03-2018 MSG_RS22860 eb61a1576db0abe4c3e096d69ea26bb5 202 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 22 199 2.0E-73 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 ProSitePatterns PS00523 Sulfatases signature 1. 81 93 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 Pfam PF00884 Sulfatase 37 450 5.5E-85 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 Gene3D G3DSA:3.40.720.10 34 477 6.6E-94 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 Gene3D G3DSA:3.30.1120.10 478 575 1.9E-14 T 29-03-2018 MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 Gene3D G3DSA:2.60.120.200 578 758 2.5E-8 T 29-03-2018 MSG_RS17390 b28650443755475ed67077f8e3cb0adb 775 SUPERFAMILY SSF53649 37 564 3.34E-125 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS12315 beff03fb22e006d315993603128cc3a4 400 PIRSF PIRSF000429 5 396 1.2E-14 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS12315 beff03fb22e006d315993603128cc3a4 400 Gene3D G3DSA:3.40.47.10 29 147 3.2E-4 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12315 beff03fb22e006d315993603128cc3a4 400 Gene3D G3DSA:3.40.47.10 157 393 4.2E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12315 beff03fb22e006d315993603128cc3a4 400 SUPERFAMILY SSF53901 248 389 7.49E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12315 beff03fb22e006d315993603128cc3a4 400 SUPERFAMILY SSF53901 10 243 1.02E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 29-03-2018 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 3.1E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.86 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 2.6E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 SMART SM00382 113 266 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 SMART SM00994 10 49 1.1E-23 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Gene3D G3DSA:1.10.8.60 317 408 9.6E-35 T 29-03-2018 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 SUPERFAMILY SSF52540 59 404 2.33E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 Gene3D G3DSA:3.40.50.300 53 315 2.1E-67 T 29-03-2018 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 7.7E-196 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MSG_RS17210 ed9647696cf51ddd231fc797b151c2c5 426 SMART SM01086 317 407 8.4E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 Gene3D G3DSA:3.30.70.1230 317 513 1.6E-36 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 SUPERFAMILY SSF158472 241 289 1.44E-6 T 29-03-2018 MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 Pfam PF00672 HAMP domain 241 288 5.9E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 SMART SM00044 288 485 6.9E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 SMART SM00304 240 292 3.0E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 SUPERFAMILY SSF55073 316 495 8.32E-43 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS22980 d4d47eae84df8f42fb6e686d4b1e360d 524 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 321 488 1.8E-19 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Gene3D G3DSA:3.30.420.40 585 736 2.9E-31 T 29-03-2018 MSG_RS11835 19362769025730593fb4b53dbe048301 766 PIRSF PIRSF006256 15 766 2.5E-262 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Pfam PF07503 HypF finger 123 155 1.5E-15 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Pfam PF07503 HypF finger 172 204 1.3E-16 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Gene3D G3DSA:3.30.70.100 9 111 9.6E-23 T 29-03-2018 MSG_RS11835 19362769025730593fb4b53dbe048301 766 ProSitePatterns PS00150 Acylphosphatase signature 1. 24 34 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS11835 19362769025730593fb4b53dbe048301 766 SUPERFAMILY SSF53067 493 529 5.18E-8 T 29-03-2018 MSG_RS11835 19362769025730593fb4b53dbe048301 766 SUPERFAMILY SSF53067 585 621 5.18E-8 T 29-03-2018 MSG_RS11835 19362769025730593fb4b53dbe048301 766 SUPERFAMILY SSF53067 660 758 5.18E-8 T 29-03-2018 MSG_RS11835 19362769025730593fb4b53dbe048301 766 SUPERFAMILY SSF55821 190 403 2.35E-40 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS11835 19362769025730593fb4b53dbe048301 766 Pfam PF01300 Telomere recombination 220 393 2.4E-42 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Pfam PF00708 Acylphosphatase 21 103 1.6E-16 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS11835 19362769025730593fb4b53dbe048301 766 Gene3D G3DSA:3.90.870.10 201 400 1.6E-47 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS11835 19362769025730593fb4b53dbe048301 766 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 23 758 1.0E-225 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MSG_RS11835 19362769025730593fb4b53dbe048301 766 SUPERFAMILY SSF54975 17 104 8.29E-19 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS12160 4b71e02ef1f2edb02eb56da9cde2bded 233 Pfam PF03551 Transcriptional regulator PadR-like family 29 102 1.7E-10 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal MSG_RS12160 4b71e02ef1f2edb02eb56da9cde2bded 233 Gene3D G3DSA:1.10.10.10 13 113 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12160 4b71e02ef1f2edb02eb56da9cde2bded 233 SUPERFAMILY SSF46785 24 196 3.64E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 273 299 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 344 368 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 376 386 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 386 409 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 303 321 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 42 61 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 152 170 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00463 E-class P450 group I signature 253 270 1.1E-26 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 379 388 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 Pfam PF00067 Cytochrome P450 24 412 1.4E-57 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 Gene3D G3DSA:1.10.630.10 25 439 5.4E-86 T 29-03-2018 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 SUPERFAMILY SSF48264 29 439 2.49E-81 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00385 P450 superfamily signature 264 281 5.4E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00385 P450 superfamily signature 304 315 5.4E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00385 P450 superfamily signature 377 386 5.4E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01450 434d0a45a586d8671f0a2e3dd0d7572e 439 PRINTS PR00385 P450 superfamily signature 386 397 5.4E-11 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Pfam PF03461 TRCF domain 1061 1135 2.2E-23 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Pfam PF02559 CarD-like/TRCF domain 523 625 1.9E-27 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Gene3D G3DSA:3.40.50.300 395 829 8.0E-32 T 29-03-2018 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SMART SM01058 522 626 6.2E-44 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF52540 399 504 5.71E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SMART SM00982 1060 1159 5.5E-38 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF143517 1051 1204 4.45E-31 T 29-03-2018 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF52540 575 833 1.52E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF52540 46 346 2.26E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Gene3D G3DSA:3.40.50.300 841 1006 7.0E-25 T 29-03-2018 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SMART SM00487 650 840 4.6E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 175 1133 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 57 1144 28.21 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Pfam PF00270 DEAD/DEAH box helicase 675 816 6.5E-15 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 Pfam PF00271 Helicase conserved C-terminal domain 859 959 1.5E-14 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SMART SM00490 876 960 3.5E-17 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF52540 832 1040 1.08E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19860 7f6424eed3fdf8942cb63402acb0ed11 1228 SUPERFAMILY SSF141259 515 596 5.36E-17 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS17565 6a7b5aa5938352aa50732572a9122b09 158 Pfam PF00578 AhpC/TSA family 10 136 1.2E-41 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS17565 6a7b5aa5938352aa50732572a9122b09 158 Gene3D G3DSA:3.40.30.10 1 156 3.1E-46 T 29-03-2018 MSG_RS17565 6a7b5aa5938352aa50732572a9122b09 158 SUPERFAMILY SSF52833 6 145 4.23E-49 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS17565 6a7b5aa5938352aa50732572a9122b09 158 PIRSF PIRSF000239 2 147 5.5E-20 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 SUPERFAMILY SSF82866 141 337 1.83E-23 T 29-03-2018 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 Gene3D G3DSA:1.20.1640.10 748 969 3.1E-20 T 29-03-2018 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 Gene3D G3DSA:1.20.1640.10 129 344 4.9E-26 T 29-03-2018 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 Gene3D G3DSA:1.20.120.570 447 563 0.17 T 29-03-2018 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 SUPERFAMILY SSF82866 761 972 3.53E-22 T 29-03-2018 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 Pfam PF03176 MMPL family 640 981 1.8E-87 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS19050 f1a910540f44887d5ba189d2df5f270a 991 Pfam PF03176 MMPL family 30 361 2.9E-89 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 SMART SM00382 31 214 7.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 308 4.4E-104 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 SUPERFAMILY SSF52540 5 228 3.55E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 Gene3D G3DSA:3.40.50.300 3 243 7.9E-63 T 29-03-2018 MSG_RS10865 e332cb3493014b45e539a0d3e0786f98 316 Pfam PF00005 ABC transporter 22 165 1.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS12655 87bc3deb0505e70bba08530265213225 403 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 318 399 2.1E-20 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12655 87bc3deb0505e70bba08530265213225 403 SUPERFAMILY SSF140459 4 175 3.4E-50 T 29-03-2018 MSG_RS12655 87bc3deb0505e70bba08530265213225 403 Pfam PF00823 PPE family 8 163 2.4E-51 T 29-03-2018 IPR000030 PPE family MSG_RS12655 87bc3deb0505e70bba08530265213225 403 Gene3D G3DSA:1.10.287.1060 23 106 2.7E-9 T 29-03-2018 MSG_RS12665 87bc3deb0505e70bba08530265213225 403 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 318 399 2.1E-20 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12665 87bc3deb0505e70bba08530265213225 403 SUPERFAMILY SSF140459 4 175 3.4E-50 T 29-03-2018 MSG_RS12665 87bc3deb0505e70bba08530265213225 403 Pfam PF00823 PPE family 8 163 2.4E-51 T 29-03-2018 IPR000030 PPE family MSG_RS12665 87bc3deb0505e70bba08530265213225 403 Gene3D G3DSA:1.10.287.1060 23 106 2.7E-9 T 29-03-2018 MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 Gene3D G3DSA:3.20.20.100 19 305 1.0E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 Pfam PF00248 Aldo/keto reductase family 29 293 1.1E-40 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 SUPERFAMILY SSF51430 21 296 1.44E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 PRINTS PR00069 Aldo-keto reductase signature 227 251 3.0E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 PRINTS PR00069 Aldo-keto reductase signature 57 81 3.0E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 PRINTS PR00069 Aldo-keto reductase signature 157 174 3.0E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS15015 0375130eb87df6b5d447e987006e5f55 305 PRINTS PR00069 Aldo-keto reductase signature 122 140 3.0E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 373 1.1E-25 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:3.90.1800.10 1056 1100 1.3E-10 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 SUPERFAMILY SSF64484 32 1139 0.0 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF10385 RNA polymerase beta subunit external 1 domain 510 576 9.8E-26 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF04565 RNA polymerase Rpb2, domain 3 432 500 5.2E-29 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 ProSitePatterns PS01166 RNA polymerases beta chain signature. 876 888 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:3.90.1100.10 317 565 2.3E-82 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:3.90.1100.10 38 275 1.1E-51 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:3.90.1100.10 566 633 3.4E-14 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF00562 RNA polymerase Rpb2, domain 6 637 1053 2.6E-158 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 249 850 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:2.40.270.10 951 1031 3.3E-18 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:2.40.270.10 834 950 4.4E-48 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:2.40.270.10 706 805 6.2E-10 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Gene3D G3DSA:2.40.50.100 634 705 5.4E-25 T 29-03-2018 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF04560 RNA polymerase Rpb2, domain 7 1055 1129 6.2E-26 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Pfam PF04563 RNA polymerase beta subunit 99 417 1.7E-21 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04205 a45b2012b35ed68215a4f8240e7b17f0 1169 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 33 1131 12.263 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 Pfam PF01658 Myo-inositol-1-phosphate synthase 200 308 2.3E-31 T 29-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 Gene3D G3DSA:3.30.360.10 211 301 1.2E-34 T 29-03-2018 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 PIRSF PIRSF015578 2 365 5.9E-97 T 29-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 Gene3D G3DSA:3.40.50.720 302 363 3.2E-15 T 29-03-2018 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 Gene3D G3DSA:3.40.50.720 3 210 2.4E-58 T 29-03-2018 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 SUPERFAMILY SSF51735 305 362 4.07E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 SUPERFAMILY SSF51735 12 194 4.07E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 SUPERFAMILY SSF55347 198 308 2.75E-34 T 29-03-2018 MSG_RS00320 a138efd049e137e419f4b6e95ce2854d 366 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 13 362 1.1E-218 T 29-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria MSG_RS20965 7949fc2f4d21d70ce6cfdc9fff1561fb 152 Gene3D G3DSA:3.30.530.20 3 143 2.4E-21 T 29-03-2018 IPR023393 START-like domain MSG_RS20965 7949fc2f4d21d70ce6cfdc9fff1561fb 152 SUPERFAMILY SSF55961 1 141 5.68E-27 T 29-03-2018 MSG_RS20965 7949fc2f4d21d70ce6cfdc9fff1561fb 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 141 7.9E-14 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Gene3D G3DSA:3.40.1030.10 82 331 8.1E-78 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 SUPERFAMILY SSF52418 87 325 6.8E-77 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 120 135 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 71 5.2E-19 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 SUPERFAMILY SSF54680 330 431 8.63E-25 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Gene3D G3DSA:1.20.970.10 3 72 2.8E-22 T 29-03-2018 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Pfam PF00591 Glycosyl transferase family, a/b domain 88 292 3.9E-35 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 415 6.7E-152 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 SUPERFAMILY SSF47648 7 74 4.97E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 SMART SM00941 343 417 1.1E-26 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 PIRSF PIRSF000478 5 432 7.3E-144 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Gene3D G3DSA:3.90.1170.30 332 423 1.1E-23 T 29-03-2018 MSG_RS05490 bea0064c84f1ee94aa298004dbdcc73e 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 415 2.2E-18 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS02320 b18e1403136af86c2f63b798904c0299 249 SUPERFAMILY SSF48498 128 245 6.53E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS02320 b18e1403136af86c2f63b798904c0299 249 Gene3D G3DSA:1.10.357.10 112 247 9.4E-10 T 29-03-2018 MSG_RS02320 b18e1403136af86c2f63b798904c0299 249 SUPERFAMILY SSF46689 54 127 2.29E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02320 b18e1403136af86c2f63b798904c0299 249 Gene3D G3DSA:1.10.10.60 44 111 1.6E-15 T 29-03-2018 MSG_RS02320 b18e1403136af86c2f63b798904c0299 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 66 108 4.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 SMART SM00382 225 401 8.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 SMART SM00962 226 425 1.0E-101 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 398 411 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 Gene3D G3DSA:3.40.50.300 222 425 7.6E-38 T 29-03-2018 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 153 424 1.4E-106 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 152 425 58.621 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 SUPERFAMILY SSF47364 124 203 1.01E-14 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 Pfam PF00448 SRP54-type protein, GTPase domain 226 425 1.6E-73 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 Gene3D G3DSA:1.20.120.140 125 215 1.5E-13 T 29-03-2018 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 Pfam PF02881 SRP54-type protein, helical bundle domain 142 205 1.7E-6 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 SMART SM00963 129 209 6.3E-14 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08120 3908eced2047f812eea2f6f7a6d392f5 425 SUPERFAMILY SSF52540 221 424 2.83E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 55 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 346 352 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 61 73 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 376 388 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 107 119 5.0E-34 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 409 532 6.0E-29 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 Pfam PF01266 FAD dependent oxidoreductase 33 356 8.0E-50 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 SUPERFAMILY SSF51905 295 356 1.26E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 SUPERFAMILY SSF51905 31 258 1.26E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 Gene3D G3DSA:3.30.9.10 218 353 1.8E-39 T 29-03-2018 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 Gene3D G3DSA:3.30.9.10 111 217 4.9E-19 T 29-03-2018 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 Gene3D G3DSA:3.50.50.60 14 94 2.9E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 37 54 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS05590 d578ad6e9d24e70e972cff55eccaa1f8 581 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 381 391 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Gene3D G3DSA:3.40.50.300 484 735 1.3E-28 T 29-03-2018 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Pfam PF17191 RecG wedge domain 12 135 3.0E-5 T 29-03-2018 IPR033454 RecG, wedge domain MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Gene3D G3DSA:3.40.50.300 273 483 2.1E-34 T 29-03-2018 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SUPERFAMILY SSF52540 204 481 2.75E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SMART SM00487 284 488 2.1E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 707 4.0E-228 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Pfam PF00270 DEAD/DEAH box helicase 289 464 4.4E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SUPERFAMILY SSF52540 418 638 7.55E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SMART SM00490 545 630 2.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SUPERFAMILY SSF50249 12 142 2.23E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 SUPERFAMILY SSF50249 169 200 2.23E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Gene3D G3DSA:2.40.50.140 50 144 8.3E-14 T 29-03-2018 MSG_RS07895 8d7fa9b10a44aef84eab699a00e0f7bc 739 Pfam PF00271 Helicase conserved C-terminal domain 511 629 2.4E-18 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS15815 f3004f75055aac40dbd8eb00bee67ed3 207 Pfam PF00753 Metallo-beta-lactamase superfamily 24 186 1.6E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS15815 f3004f75055aac40dbd8eb00bee67ed3 207 SMART SM00849 23 186 2.0E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS15815 f3004f75055aac40dbd8eb00bee67ed3 207 SUPERFAMILY SSF56281 10 199 4.59E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS15815 f3004f75055aac40dbd8eb00bee67ed3 207 Gene3D G3DSA:3.60.15.10 4 206 9.4E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13540 ef577ee13b1e531a3c51cfb92641b24e 285 Pfam PF00296 Luciferase-like monooxygenase 11 242 4.8E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS13540 ef577ee13b1e531a3c51cfb92641b24e 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 21 257 1.0E-52 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS13540 ef577ee13b1e531a3c51cfb92641b24e 285 Gene3D G3DSA:3.20.20.30 1 276 8.2E-71 T 29-03-2018 MSG_RS13540 ef577ee13b1e531a3c51cfb92641b24e 285 SUPERFAMILY SSF51679 10 259 1.44E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS13540 ef577ee13b1e531a3c51cfb92641b24e 285 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 7 224 1.0E-71 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 SUPERFAMILY SSF51735 11 241 8.18E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 Gene3D G3DSA:3.40.50.720 7 263 5.2E-50 T 29-03-2018 MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22020 43ce26b1ae67908bdab62994557a18f0 275 Pfam PF00106 short chain dehydrogenase 13 201 9.1E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 Gene3D G3DSA:3.40.630.10 52 485 2.7E-55 T 29-03-2018 MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 Pfam PF04389 Peptidase family M28 255 467 2.9E-45 T 29-03-2018 IPR007484 Peptidase M28 MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 SUPERFAMILY SSF53187 51 104 2.78E-56 T 29-03-2018 MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 SUPERFAMILY SSF53187 239 481 2.78E-56 T 29-03-2018 MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 SUPERFAMILY SSF52025 128 207 6.15E-12 T 29-03-2018 MSG_RS03055 e233870ddb72be940c3fe0ea2a47a33d 503 Pfam PF02225 PA domain 143 233 2.5E-14 T 29-03-2018 IPR003137 PA domain MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 Gene3D G3DSA:3.40.50.720 1 289 1.0E-63 T 29-03-2018 MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.8E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 Pfam PF00106 short chain dehydrogenase 16 206 3.7E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19900 2971b3c5beca6cd43ad6b2673a7d6ac8 289 SUPERFAMILY SSF51735 11 240 1.46E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11900 6eb7a3ff8ed463b0e19c096956426a72 225 Pfam PF00694 Aconitase C-terminal domain 7 125 3.1E-25 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11900 6eb7a3ff8ed463b0e19c096956426a72 225 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 6 191 2.7E-50 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MSG_RS11900 6eb7a3ff8ed463b0e19c096956426a72 225 Gene3D G3DSA:3.20.19.10 1 180 4.7E-34 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS11900 6eb7a3ff8ed463b0e19c096956426a72 225 SUPERFAMILY SSF52016 8 197 1.29E-42 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS00940 1dd3d123de82dc142afc3ea7312f15f8 466 Gene3D G3DSA:1.10.510.10 3 180 3.0E-4 T 29-03-2018 MSG_RS00940 1dd3d123de82dc142afc3ea7312f15f8 466 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 56 450 2.6E-119 T 29-03-2018 IPR018721 Protein of unknown function DUF2252 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 SMART SM01329 12 399 1.8E-130 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 12 395 4.7E-71 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 6 407 5.2E-204 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 274 293 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 SUPERFAMILY SSF53659 5 407 3.07E-150 T 29-03-2018 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 Gene3D G3DSA:3.40.718.10 4 408 3.7E-131 T 29-03-2018 MSG_RS05380 00caac8cab1a4f043f48d948cedf10b2 408 PIRSF PIRSF000108 1 408 2.8E-221 T 29-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 Gene3D G3DSA:1.10.1740.10 2 68 3.2E-15 T 29-03-2018 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 Pfam PF04542 Sigma-70 region 2 14 73 1.2E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 SUPERFAMILY SSF88659 99 160 5.23E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 SUPERFAMILY SSF88946 8 81 4.32E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 Pfam PF08281 Sigma-70, region 4 106 157 1.5E-7 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 160 8.2E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04120 bc3d5108da8c24fddb30aad6da43ad70 412 Gene3D G3DSA:1.10.10.10 69 161 8.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Pfam PF01061 ABC-2 type transporter 614 829 3.0E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Gene3D G3DSA:2.60.200.20 9 115 3.4E-18 T 29-03-2018 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Gene3D G3DSA:2.60.200.20 124 334 1.1E-19 T 29-03-2018 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Pfam PF00005 ABC transporter 353 499 3.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Pfam PF00498 FHA domain 26 89 5.8E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Pfam PF00498 FHA domain 250 312 7.4E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 Gene3D G3DSA:3.40.50.300 335 604 2.9E-63 T 29-03-2018 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SUPERFAMILY SSF49879 204 318 2.68E-24 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SMART SM00240 248 298 2.2E-11 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SMART SM00240 25 75 2.0E-11 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SUPERFAMILY SSF49879 16 118 8.03E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SMART SM00382 362 556 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 SUPERFAMILY SSF52540 332 551 7.67E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05295 2e878ce05ad753bf80199ba117340840 883 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 SUPERFAMILY SSF52540 2 207 2.43E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 SUPERFAMILY SSF52540 991 1182 2.43E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1189 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 SUPERFAMILY SSF75553 464 668 5.23E-31 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 SMART SM00968 510 623 2.4E-22 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Gene3D G3DSA:3.40.50.300 2 211 3.6E-40 T 29-03-2018 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Gene3D G3DSA:1.20.1170.10 768 1047 3.8E-4 T 29-03-2018 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Gene3D G3DSA:1.20.1170.10 434 767 3.6E-8 T 29-03-2018 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Gene3D G3DSA:3.40.50.300 1048 1197 1.0E-15 T 29-03-2018 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Gene3D G3DSA:1.20.5.50 323 433 1.6E-5 T 29-03-2018 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1191 22.386 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 PIRSF PIRSF005719 1 1196 6.2E-272 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1181 2.5E-72 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MSG_RS08110 a0fc00afe395d6d8c3fee6a75ce7e2b1 1202 Pfam PF06470 SMC proteins Flexible Hinge Domain 511 622 2.5E-21 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 Gene3D G3DSA:3.40.1060.10 160 292 5.5E-38 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 137 152 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 290 304 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 112 120 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 400 413 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 123 136 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 199 212 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 213 226 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 PRINTS PR00415 Aconitase family signature 344 355 1.7E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 Gene3D G3DSA:3.30.499.10 1 159 3.5E-32 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 SUPERFAMILY SSF53732 4 466 1.24E-138 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 Gene3D G3DSA:3.30.499.10 325 467 2.5E-47 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS11905 6f348c7bf148089c4aaabea1b400da62 467 Pfam PF00330 Aconitase family (aconitate hydratase) 10 458 2.9E-131 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 411 2.5E-214 T 29-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 411 52.97 T 29-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 Gene3D G3DSA:3.40.50.620 1 328 8.0E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 38 335 6.9E-81 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 Gene3D G3DSA:1.20.120.640 329 411 5.5E-16 T 29-03-2018 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 SUPERFAMILY SSF52374 25 334 1.82E-68 T 29-03-2018 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 243 264 7.3E-25 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 7.3E-25 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 7.3E-25 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS14905 883b9c34175bdb24d324f9bcca4b66ee 411 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 212 230 7.3E-25 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MSG_RS16860 2484202806be25417624097eb722f2b3 555 SUPERFAMILY SSF56014 408 554 7.07E-37 T 29-03-2018 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 162 313 3.1E-37 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 548 7.9E-11 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Gene3D G3DSA:3.90.480.10 278 407 7.6E-28 T 29-03-2018 MSG_RS16860 2484202806be25417624097eb722f2b3 555 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 461 477 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 PRINTS PR00397 Sirohaem Fe-binding site signature 461 479 3.2E-9 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 PRINTS PR00397 Sirohaem Fe-binding site signature 412 430 3.2E-9 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 SUPERFAMILY SSF55124 11 161 5.56E-37 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 SUPERFAMILY SSF55124 292 423 7.69E-20 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Gene3D G3DSA:3.30.413.10 163 277 6.9E-22 T 29-03-2018 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Gene3D G3DSA:3.30.413.10 408 555 2.7E-28 T 29-03-2018 MSG_RS16860 2484202806be25417624097eb722f2b3 555 SUPERFAMILY SSF56014 162 320 1.06E-44 T 29-03-2018 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 92 152 7.5E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS16860 2484202806be25417624097eb722f2b3 555 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 338 400 3.7E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Gene3D G3DSA:3.30.450.40 189 354 1.1E-20 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SUPERFAMILY SSF55781 33 205 1.31E-24 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Pfam PF01590 GAF domain 51 177 7.6E-8 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Gene3D G3DSA:3.30.450.40 355 493 3.4E-6 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Gene3D G3DSA:3.30.565.10 731 857 3.4E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Pfam PF13581 Histidine kinase-like ATPase domain 738 853 1.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SUPERFAMILY SSF55781 191 356 8.29E-19 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SUPERFAMILY SSF81606 532 727 1.33E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Pfam PF13185 GAF domain 213 347 1.8E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SUPERFAMILY SSF55874 761 852 1.7E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SMART SM00065 212 357 0.0026 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SMART SM00065 51 187 8.9E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Gene3D G3DSA:3.30.450.40 23 188 7.6E-26 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Gene3D G3DSA:3.60.40.10 494 730 8.2E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 SMART SM00331 518 730 3.1E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS11955 4ba7c5c28daea9c00b2cd90b4a73cfb8 857 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 545 730 1.2E-43 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS06000 303c5b651340040d4ecfe15578c286b4 210 Pfam PF01545 Cation efflux family 19 187 1.7E-10 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MSG_RS06000 303c5b651340040d4ecfe15578c286b4 210 Gene3D G3DSA:1.20.1510.10 6 195 7.4E-18 T 29-03-2018 MSG_RS06000 303c5b651340040d4ecfe15578c286b4 210 SUPERFAMILY SSF161111 9 192 1.26E-27 T 29-03-2018 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 151 2.6E-62 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 148 29.371 T 29-03-2018 IPR033747 Class I PurE MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 PIRSF PIRSF001338 1 155 6.4E-64 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 Gene3D G3DSA:3.40.50.7700 1 153 3.7E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 SMART SM01001 1 144 3.1E-85 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 Pfam PF00731 AIR carboxylase 1 141 2.2E-61 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MSG_RS05730 ebd7f3aeb6e074bc75899542fb87bf15 161 SUPERFAMILY SSF52255 1 154 1.83E-61 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 32 442 46.074 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 157 442 1.4E-108 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 Gene3D G3DSA:1.10.645.10 36 236 1.1E-48 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 40 442 2.0E-181 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 77 88 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 Gene3D G3DSA:1.10.645.10 237 438 9.2E-41 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06750 5d4a492c7f13fc6c42ffad7dc4b7e09c 442 SUPERFAMILY SSF56762 50 442 1.96E-118 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 Gene3D G3DSA:3.20.20.140 21 286 1.2E-77 T 29-03-2018 MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 23 280 2.8E-78 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 Pfam PF01026 TatD related DNase 24 279 3.8E-65 T 29-03-2018 IPR001130 TatD family GO:0016788 MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 SUPERFAMILY SSF51556 23 281 2.17E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 216 232 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MSG_RS19945 0175df2d46cc44a065ea50f934f7dcca 286 PIRSF PIRSF005902 15 284 3.3E-67 T 29-03-2018 IPR001130 TatD family GO:0016788 MSG_RS12570 d40a4cc0023c7c79fc63844f8efe2b26 406 Pfam PF02515 CoA-transferase family III 5 382 3.7E-83 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS12570 d40a4cc0023c7c79fc63844f8efe2b26 406 SUPERFAMILY SSF89796 3 404 2.75E-97 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS12570 d40a4cc0023c7c79fc63844f8efe2b26 406 Gene3D G3DSA:3.40.50.10540 1 406 1.4E-96 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 SUPERFAMILY SSF48008 92 219 2.88E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 Pfam PF07729 FCD domain 93 217 3.0E-21 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 7.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 7.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 Gene3D G3DSA:1.10.10.10 1 74 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 Gene3D G3DSA:1.20.120.530 86 222 3.7E-23 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 3.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 SUPERFAMILY SSF46785 3 76 2.73E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 SMART SM00345 13 72 4.0E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10120 62b204ccdc5d71e8cdbe83617c082084 223 SMART SM00895 93 220 1.1E-21 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS19490 4cd2b78fe0ff8620932c7f5998476ee3 164 Gene3D G3DSA:2.30.110.10 9 153 2.4E-28 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS19490 4cd2b78fe0ff8620932c7f5998476ee3 164 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 49 152 6.6E-23 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS19490 4cd2b78fe0ff8620932c7f5998476ee3 164 Pfam PF04075 F420H(2)-dependent quinone reductase 44 152 2.0E-26 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS24510 d656869856e96a633f2e25751027771b 96 Pfam PF06013 Proteins of 100 residues with WXG 8 89 3.6E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24510 d656869856e96a633f2e25751027771b 96 SUPERFAMILY SSF140453 6 95 2.88E-20 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24510 d656869856e96a633f2e25751027771b 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 90 1.5E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24510 d656869856e96a633f2e25751027771b 96 Gene3D G3DSA:1.10.287.1060 3 96 7.9E-16 T 29-03-2018 MSG_RS09110 d80229e2423d5a45d21fa0a3ab5e02a6 487 Gene3D G3DSA:3.30.70.1450 406 487 4.8E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09110 d80229e2423d5a45d21fa0a3ab5e02a6 487 SUPERFAMILY SSF116726 407 485 2.49E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09110 d80229e2423d5a45d21fa0a3ab5e02a6 487 Pfam PF00999 Sodium/hydrogen exchanger family 17 387 5.5E-52 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MSG_RS17415 9394b80fca04fea3942926ca647f43cd 237 Pfam PF11209 Protein of unknown function (DUF2993) 17 217 1.1E-18 T 29-03-2018 IPR021373 Protein of unknown function DUF2993 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Gene3D G3DSA:3.40.50.300 337 762 4.4E-5 T 29-03-2018 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Gene3D G3DSA:1.10.510.10 109 336 1.0E-41 T 29-03-2018 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Pfam PF13191 AAA ATPase domain 314 449 8.1E-11 T 29-03-2018 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 SUPERFAMILY SSF56112 23 266 9.31E-65 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 52 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Gene3D G3DSA:1.25.40.10 790 1075 2.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Gene3D G3DSA:3.30.200.20 21 108 3.9E-21 T 29-03-2018 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 SMART SM00220 23 267 1.0E-49 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 PIRSF PIRSF000574 283 1078 8.9E-283 T 29-03-2018 IPR016236 Serine/threonine-protein kinase PknK, predicted KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 PIRSF PIRSF000574 27 291 7.8E-119 T 29-03-2018 IPR016236 Serine/threonine-protein kinase PknK, predicted KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 Pfam PF00069 Protein kinase domain 26 255 3.5E-41 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12005 2858f11a6f4b15885cc560d24a9f3a25 1078 SUPERFAMILY SSF52540 315 458 1.1E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17835 55da37872f9dc6977821c5225907ecc3 413 Gene3D G3DSA:1.10.287.1060 21 101 1.4E-4 T 29-03-2018 MSG_RS17835 55da37872f9dc6977821c5225907ecc3 413 SUPERFAMILY SSF140459 2 173 1.12E-60 T 29-03-2018 MSG_RS17835 55da37872f9dc6977821c5225907ecc3 413 Pfam PF00823 PPE family 6 160 9.1E-60 T 29-03-2018 IPR000030 PPE family MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 Pfam PF00994 Probable molybdopterin binding domain 8 175 6.7E-37 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 280 425 3.2E-45 T 29-03-2018 IPR008136 CinA, C-terminal MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 SMART SM00852 8 181 5.9E-40 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 Gene3D G3DSA:3.40.980.10 4 182 1.0E-46 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 SUPERFAMILY SSF142433 273 425 1.29E-50 T 29-03-2018 IPR008136 CinA, C-terminal MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 431 138.164 T 29-03-2018 IPR008135 Competence-induced protein CinA MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 SUPERFAMILY SSF53218 6 217 2.49E-38 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 PIRSF PIRSF006728 4 430 4.5E-126 T 29-03-2018 IPR008135 Competence-induced protein CinA MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 6 426 2.7E-76 T 29-03-2018 IPR008135 Competence-induced protein CinA MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 Gene3D G3DSA:3.90.950.20 258 430 1.1E-55 T 29-03-2018 MSG_RS13295 ee64d02bf2c0517edd99c228b506a31d 431 Pfam PF02464 Competence-damaged protein 275 425 1.6E-52 T 29-03-2018 IPR008136 CinA, C-terminal MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Gene3D G3DSA:3.40.50.1000 1078 1201 1.4E-23 T 29-03-2018 IPR023214 HAD-like domain MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Gene3D G3DSA:2.70.150.10 584 819 2.6E-27 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Gene3D G3DSA:1.20.1110.10 1202 1413 9.8E-22 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Pfam PF00122 E1-E2 ATPase 720 897 9.3E-34 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF81653 718 816 3.66E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Gene3D G3DSA:3.40.50.1000 263 536 0.33 T 29-03-2018 IPR023214 HAD-like domain MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Gene3D G3DSA:3.40.1110.10 875 1077 8.0E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1148 1164 9.2E-11 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1208 1233 9.2E-11 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1176 1192 9.2E-11 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1027 1045 9.2E-11 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1176 1195 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1096 1106 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1074 1085 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 918 932 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1200 1212 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 758 772 4.3E-28 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF81665 820 912 2.35E-40 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF81665 1226 1408 2.35E-40 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF81665 643 710 2.35E-40 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1144 1263 1.3E-23 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 682 1120 4.3E-36 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Pfam PF00702 haloacid dehalogenase-like hydrolase 915 1189 5.8E-22 T 29-03-2018 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 Pfam PF00689 Cation transporting ATPase, C-terminus 1261 1407 1.2E-10 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF56784 1024 1279 6.31E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS17755 9381209627da1ea6d69d6e5396fe4709 1475 SUPERFAMILY SSF56784 916 936 6.31E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.4E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 1.4E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 64 79 1.4E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.4E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 Gene3D G3DSA:3.40.50.1820 15 286 1.9E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 SUPERFAMILY SSF53474 15 284 2.39E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21470 ff2ac8fe59989b79c6a2741ea49531eb 287 Pfam PF12697 Alpha/beta hydrolase family 41 277 2.4E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 184 423 1.0E-21 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 SUPERFAMILY SSF50022 15 163 2.75E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 Gene3D G3DSA:3.90.380.10 147 440 2.6E-55 T 29-03-2018 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 SUPERFAMILY SSF55961 163 425 3.53E-32 T 29-03-2018 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 1.5E-11 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 63 78 1.5E-11 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 33 58 1.5E-11 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.5E-11 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 91 113 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 Gene3D G3DSA:2.102.10.10 46 146 1.7E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12535 e8d5d9d1b31f09a82d14bb41d96e3a54 460 Pfam PF00355 Rieske [2Fe-2S] domain 49 122 1.4E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 227 1.9E-56 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 Gene3D G3DSA:3.40.50.150 2 227 9.5E-34 T 29-03-2018 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 SUPERFAMILY SSF53335 8 153 1.53E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 SUPERFAMILY SSF53335 181 227 1.53E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 1.6E-70 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 32.508 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS03865 5d0722f3a73950b5fc472062fea4fa8b 230 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MSG_RS18675 20d44099462dd1693bf82a85deefbfe5 379 Pfam PF01757 Acyltransferase family 23 372 1.5E-27 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS10665 38d9571223857318e14e97f202798772 335 Hamap MF_01340 UPF0353 protein . 9 335 55.822 T 29-03-2018 IPR022933 Uncharacterised protein family UPF0353 MSG_RS10665 38d9571223857318e14e97f202798772 335 Pfam PF07584 Aerotolerance regulator N-terminal 14 86 3.2E-6 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal MSG_RS10665 38d9571223857318e14e97f202798772 335 SMART SM00327 96 274 6.1E-28 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS10665 38d9571223857318e14e97f202798772 335 Gene3D G3DSA:3.40.50.410 91 308 1.9E-38 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS10665 38d9571223857318e14e97f202798772 335 Pfam PF13519 von Willebrand factor type A domain 99 212 3.6E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS10665 38d9571223857318e14e97f202798772 335 SUPERFAMILY SSF53300 94 297 9.32E-30 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS00785 f3fb6d116ca98546a1d449b0c8860b4b 346 Pfam PF07859 alpha/beta hydrolase fold 115 320 1.7E-60 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS00785 f3fb6d116ca98546a1d449b0c8860b4b 346 Gene3D G3DSA:3.40.50.1820 55 346 2.5E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00785 f3fb6d116ca98546a1d449b0c8860b4b 346 SUPERFAMILY SSF53474 91 336 3.68E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20480 25980d648c07d8c3614ca3f7f48ee7a7 332 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 31 325 1.3E-88 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MSG_RS20480 25980d648c07d8c3614ca3f7f48ee7a7 332 Gene3D G3DSA:1.10.3720.10 26 324 1.4E-34 T 29-03-2018 MSG_RS20480 25980d648c07d8c3614ca3f7f48ee7a7 332 SUPERFAMILY SSF161098 50 322 3.92E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS20480 25980d648c07d8c3614ca3f7f48ee7a7 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 323 1.5E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 Gene3D G3DSA:3.40.50.720 202 365 2.3E-36 T 29-03-2018 MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 Gene3D G3DSA:3.40.50.720 9 197 3.5E-40 T 29-03-2018 MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 SMART SM01002 151 313 1.0E-76 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 SUPERFAMILY SSF51735 143 318 1.41E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 SMART SM01003 12 142 1.9E-56 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 12 141 8.6E-40 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 SUPERFAMILY SSF52283 10 173 8.08E-47 T 29-03-2018 MSG_RS01545 b7f3169b8b3834ac5645f6b69c06b8d4 366 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 146 362 2.2E-65 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 Pfam PF16864 Dimerisation domain 52 121 1.0E-7 T 29-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 PIRSF PIRSF005739 27 372 8.2E-51 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 Gene3D G3DSA:1.10.10.10 40 130 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 SUPERFAMILY SSF53335 129 369 1.14E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 Pfam PF00891 O-methyltransferase 144 355 3.8E-48 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 Gene3D G3DSA:3.40.50.150 131 374 9.0E-44 T 29-03-2018 MSG_RS07100 849116206c5afe7a44205d33b9c7465c 374 SUPERFAMILY SSF46785 48 126 5.97E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10630 2fc6bbe6c4b21f86ed499f57f4950acd 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10630 2fc6bbe6c4b21f86ed499f57f4950acd 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10630 2fc6bbe6c4b21f86ed499f57f4950acd 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.5E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10630 2fc6bbe6c4b21f86ed499f57f4950acd 198 Gene3D G3DSA:1.10.357.10 3 188 8.8E-34 T 29-03-2018 MSG_RS10630 2fc6bbe6c4b21f86ed499f57f4950acd 198 SUPERFAMILY SSF46689 5 73 1.44E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 22 1049 13.842 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 562 5.6E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 420 435 5.6E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 246 269 5.6E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 589 598 5.6E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 61 72 5.6E-32 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 SUPERFAMILY SSF47323 685 909 1.85E-43 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 SUPERFAMILY SSF52374 28 218 3.92E-127 T 29-03-2018 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 SUPERFAMILY SSF52374 422 663 3.92E-127 T 29-03-2018 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 SUPERFAMILY SSF47323 972 1052 3.53E-5 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 30 864 3.4E-242 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Pfam PF08264 Anticodon-binding domain of tRNA 712 850 3.7E-21 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Gene3D G3DSA:3.40.50.620 49 217 2.9E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 79 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 38 664 1.4E-180 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Gene3D G3DSA:1.10.730.10 615 845 7.1E-48 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 SUPERFAMILY SSF50677 224 401 3.35E-48 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MSG_RS10935 51ade4f10d75cbe6b3fb8a106657a560 1053 Gene3D G3DSA:3.90.740.10 224 507 2.5E-88 T 29-03-2018 MSG_RS08795 b194b68dc49716b330111afed4c82217 253 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 7 241 28.334 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS08795 b194b68dc49716b330111afed4c82217 253 SUPERFAMILY SSF69796 35 238 8.24E-63 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS08795 b194b68dc49716b330111afed4c82217 253 Pfam PF02511 Thymidylate synthase complementing protein 36 227 3.3E-55 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS08795 b194b68dc49716b330111afed4c82217 253 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 233 3.2E-65 T 29-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 Gene3D G3DSA:1.20.1250.20 9 197 5.0E-27 T 29-03-2018 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 Pfam PF07690 Major Facilitator Superfamily 20 286 4.0E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 4.4E-5 T 29-03-2018 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 4.4E-5 T 29-03-2018 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 4.4E-5 T 29-03-2018 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 Gene3D G3DSA:1.20.1250.20 260 461 8.2E-16 T 29-03-2018 MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 SUPERFAMILY SSF103473 8 198 3.01E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS00585 73272219b1a6c4cc5c0211d8735aa731 462 SUPERFAMILY SSF103473 249 456 3.01E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS11145 e97ad82ee474901148db75b950db6996 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 4.0E-19 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS11145 e97ad82ee474901148db75b950db6996 341 Gene3D G3DSA:3.40.50.720 175 310 6.3E-12 T 29-03-2018 MSG_RS11145 e97ad82ee474901148db75b950db6996 341 SUPERFAMILY SSF51735 175 309 1.75E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11145 e97ad82ee474901148db75b950db6996 341 Gene3D G3DSA:3.90.180.10 1 174 1.1E-32 T 29-03-2018 MSG_RS11145 e97ad82ee474901148db75b950db6996 341 SUPERFAMILY SSF50129 1 174 6.13E-42 T 29-03-2018 IPR011032 GroES-like MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 471 19.758 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 226 451 5.4E-42 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 200 8.1E-26 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 292 302 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Gene3D G3DSA:3.40.1190.20 208 473 4.5E-44 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Pfam PF01256 Carbohydrate kinase 234 464 1.0E-69 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 SUPERFAMILY SSF53613 213 470 9.82E-60 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 SUPERFAMILY SSF64153 3 231 7.06E-46 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 PIRSF PIRSF017184 4 473 7.0E-91 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 200 19.254 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Pfam PF03853 YjeF-related protein N-terminus 25 182 2.1E-35 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 408 418 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MSG_RS04975 58d212cdee6c942ed0d929a9f4df6a75 473 Gene3D G3DSA:3.40.50.10260 2 206 2.9E-49 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MSG_RS19220 86a4d2a11730653647069c029d10977a 360 SUPERFAMILY SSF89796 3 347 1.03E-108 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS19220 86a4d2a11730653647069c029d10977a 360 Gene3D G3DSA:3.40.50.10540 1 358 1.1E-108 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS19220 86a4d2a11730653647069c029d10977a 360 Pfam PF02515 CoA-transferase family III 5 345 1.0E-79 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS05205 e7e9293aca3c9da66240354ae9dde1d1 234 PIRSF PIRSF000709 26 123 1.4E-5 T 29-03-2018 MSG_RS05205 e7e9293aca3c9da66240354ae9dde1d1 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 34 226 8.3E-28 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS05205 e7e9293aca3c9da66240354ae9dde1d1 234 SMART SM00855 33 187 3.8E-12 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS05205 e7e9293aca3c9da66240354ae9dde1d1 234 SUPERFAMILY SSF53254 33 227 2.36E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS05205 e7e9293aca3c9da66240354ae9dde1d1 234 Gene3D G3DSA:3.40.50.1240 31 233 1.8E-30 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS13800 db4c6f012172054b05ab3155d04fdc21 47 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 9 46 2.9E-9 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 SUPERFAMILY SSF56801 16 505 4.58E-94 T 29-03-2018 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Pfam PF00501 AMP-binding enzyme 24 408 2.8E-54 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Gene3D G3DSA:3.40.50.980 163 315 3.5E-31 T 29-03-2018 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Gene3D G3DSA:3.40.50.980 2 162 9.2E-21 T 29-03-2018 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 494 7.8E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Gene3D G3DSA:3.30.300.30 403 508 4.3E-16 T 29-03-2018 MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS00865 8e615c78d2f060594f55b488b80b5b22 545 Gene3D G3DSA:2.30.38.10 325 402 3.7E-14 T 29-03-2018 MSG_RS23140 5f41f67231d1ddb48ebc4e8a4d0daaa1 263 SMART SM00849 38 193 1.9E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23140 5f41f67231d1ddb48ebc4e8a4d0daaa1 263 Gene3D G3DSA:3.60.15.10 35 258 3.4E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23140 5f41f67231d1ddb48ebc4e8a4d0daaa1 263 SUPERFAMILY SSF56281 17 262 3.36E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23140 5f41f67231d1ddb48ebc4e8a4d0daaa1 263 Pfam PF00753 Metallo-beta-lactamase superfamily 36 193 1.2E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 SUPERFAMILY SSF52821 221 333 1.13E-11 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 SUPERFAMILY SSF52821 352 445 1.17E-21 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 SMART SM00849 17 182 1.5E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 Pfam PF00581 Rhodanese-like domain 360 444 2.4E-9 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 Gene3D G3DSA:3.60.15.10 2 242 2.2E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 Gene3D G3DSA:3.40.250.10 247 341 1.3E-4 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 Gene3D G3DSA:3.40.250.10 349 457 9.8E-21 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 SMART SM00450 357 451 3.6E-15 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16495 6dedf3664cefcbd94e38e3c21ce800ee 457 SUPERFAMILY SSF56281 15 246 1.15E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Gene3D G3DSA:3.40.50.980 172 327 4.7E-31 T 29-03-2018 MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Pfam PF00501 AMP-binding enzyme 13 422 1.5E-75 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Gene3D G3DSA:3.30.300.30 417 532 1.4E-18 T 29-03-2018 MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Gene3D G3DSA:3.40.50.980 5 171 3.8E-32 T 29-03-2018 MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Gene3D G3DSA:2.30.38.10 328 415 1.3E-19 T 29-03-2018 MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 511 7.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS15655 8a453d85e9f1451f1f72bdd20e8408e5 532 SUPERFAMILY SSF56801 7 522 8.9E-110 T 29-03-2018 MSG_RS19055 0da9d1d42eed0f7ba7668f9c4a50ec6a 472 SUPERFAMILY SSF52777 238 466 3.67E-22 T 29-03-2018 MSG_RS19055 0da9d1d42eed0f7ba7668f9c4a50ec6a 472 Gene3D G3DSA:3.30.559.10 22 234 3.0E-9 T 29-03-2018 MSG_RS19055 0da9d1d42eed0f7ba7668f9c4a50ec6a 472 Pfam PF00668 Condensation domain 71 378 1.2E-16 T 29-03-2018 IPR001242 Condensation domain MSG_RS19055 0da9d1d42eed0f7ba7668f9c4a50ec6a 472 SUPERFAMILY SSF52777 41 212 1.07E-16 T 29-03-2018 MSG_RS13375 6837147b81781ee3b77355c8a23569e0 62 Gene3D G3DSA:1.10.10.10 23 62 3.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13375 6837147b81781ee3b77355c8a23569e0 62 SUPERFAMILY SSF46785 1 55 9.21E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13375 6837147b81781ee3b77355c8a23569e0 62 Gene3D G3DSA:1.10.10.10 1 22 0.15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11080 ed0561fff833da61a8ef32ca1c926823 168 Pfam PF13563 2'-5' RNA ligase superfamily 29 142 2.0E-9 T 29-03-2018 MSG_RS11080 ed0561fff833da61a8ef32ca1c926823 168 SUPERFAMILY SSF55144 1 129 1.73E-10 T 29-03-2018 IPR009097 Cyclic phosphodiesterase MSG_RS11080 ed0561fff833da61a8ef32ca1c926823 168 Gene3D G3DSA:3.90.1140.10 2 161 3.4E-15 T 29-03-2018 MSG_RS13595 6a450f0cd44c3410d9b8dd95acd94d70 418 Gene3D G3DSA:3.40.50.2000 1 223 3.6E-13 T 29-03-2018 MSG_RS13595 6a450f0cd44c3410d9b8dd95acd94d70 418 Gene3D G3DSA:3.40.50.2000 224 389 1.4E-39 T 29-03-2018 MSG_RS13595 6a450f0cd44c3410d9b8dd95acd94d70 418 Pfam PF00534 Glycosyl transferases group 1 225 384 3.2E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS13595 6a450f0cd44c3410d9b8dd95acd94d70 418 Pfam PF13439 Glycosyltransferase Family 4 15 216 1.5E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS13595 6a450f0cd44c3410d9b8dd95acd94d70 418 SUPERFAMILY SSF53756 2 407 1.41E-80 T 29-03-2018 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 167 322 1.2E-68 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 334 4.3E-132 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 183 199 7.0E-38 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 239 256 7.0E-38 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 120 133 7.0E-38 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 156 174 7.0E-38 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 279 294 7.0E-38 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 SUPERFAMILY SSF51735 2 161 3.59E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 Gene3D G3DSA:3.40.50.720 1 171 6.4E-71 T 29-03-2018 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 113 6.9E-32 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 160 167 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 Gene3D G3DSA:3.30.360.10 172 324 2.1E-67 T 29-03-2018 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 PIRSF PIRSF000149 1 342 4.9E-128 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 SUPERFAMILY SSF55347 161 322 1.65E-71 T 29-03-2018 MSG_RS10450 0b1fd144d726115f8a91725db8dea69e 343 SMART SM00846 3 162 3.5E-83 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 SUPERFAMILY SSF52540 543 707 4.06E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 SUPERFAMILY SSF52540 225 503 4.06E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 SUPERFAMILY SSF52540 760 806 4.06E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 SUPERFAMILY SSF52540 16 192 4.06E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 SUPERFAMILY SSF52980 937 1055 1.77E-6 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Gene3D G3DSA:3.40.50.300 341 812 7.6E-47 T 29-03-2018 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Gene3D G3DSA:3.90.320.10 891 1077 6.8E-15 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Pfam PF12705 PD-(D/E)XK nuclease superfamily 906 1075 1.5E-11 T 29-03-2018 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Pfam PF13361 UvrD-like helicase C-terminal domain 355 506 7.9E-10 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Pfam PF13361 UvrD-like helicase C-terminal domain 668 782 2.3E-18 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 337 4.4E-41 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MSG_RS06280 d09f080f2f9d63a20ee13acc947865b8 1105 Gene3D G3DSA:3.40.50.300 19 340 3.4E-46 T 29-03-2018 MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 SUPERFAMILY SSF63411 264 446 3.0E-43 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 Pfam PF00675 Insulinase (Peptidase family M16) 42 188 2.9E-34 T 29-03-2018 IPR011765 Peptidase M16, N-terminal MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 63 86 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 Gene3D G3DSA:3.30.830.10 13 248 1.5E-61 T 29-03-2018 MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 Pfam PF05193 Peptidase M16 inactive domain 196 371 3.8E-40 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 SUPERFAMILY SSF63411 31 235 7.88E-57 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MSG_RS08635 99fb4aef80b59afed0b765044d11ad83 455 Gene3D G3DSA:3.30.830.10 250 449 7.6E-42 T 29-03-2018 MSG_RS10830 8bf5ec7a83df3659996154a98327077f 407 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 1.1E-60 T 29-03-2018 IPR013691 C-methyltransferase MSG_RS10830 8bf5ec7a83df3659996154a98327077f 407 Pfam PF13489 Methyltransferase domain 98 238 1.7E-8 T 29-03-2018 MSG_RS10830 8bf5ec7a83df3659996154a98327077f 407 Gene3D G3DSA:3.40.50.150 55 255 5.5E-24 T 29-03-2018 MSG_RS10830 8bf5ec7a83df3659996154a98327077f 407 SUPERFAMILY SSF53335 57 253 5.63E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10830 8bf5ec7a83df3659996154a98327077f 407 Pfam PF08421 Putative zinc binding domain 3 64 1.9E-20 T 29-03-2018 IPR013630 Methyltransferase putative zinc binding domain MSG_RS06260 6635b9a3a22ce98c7baf1161a4e60232 284 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 4 280 2.1E-132 T 29-03-2018 IPR013402 Conserved hypothetical protein CHP02569 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 SUPERFAMILY SSF55347 129 244 2.48E-24 T 29-03-2018 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 SUPERFAMILY SSF51735 11 156 1.19E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 Gene3D G3DSA:3.30.360.10 144 244 6.7E-34 T 29-03-2018 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 17 120 4.8E-10 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 10 273 29.127 T 29-03-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 Pfam PF01958 Domain of unknown function DUF108 175 261 4.5E-28 T 29-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 PIRSF PIRSF005227 8 275 4.4E-70 T 29-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 MSG_RS20850 52b5046448bb0f7b84cc522b191629ea 275 Gene3D G3DSA:3.40.50.720 6 143 1.1E-14 T 29-03-2018 MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 SUPERFAMILY SSF51430 8 305 2.1E-98 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 Pfam PF00248 Aldo/keto reductase family 13 305 1.5E-76 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 Gene3D G3DSA:3.20.20.100 1 319 6.3E-97 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.2E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 PRINTS PR00069 Aldo-keto reductase signature 106 124 1.2E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS14225 5f0e6c5560d3caa3680fefb17666ad8b 323 PRINTS PR00069 Aldo-keto reductase signature 239 263 1.2E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 SMART SM00893 24 219 2.0E-50 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 Gene3D G3DSA:3.40.50.620 2 266 2.7E-64 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 Pfam PF01012 Electron transfer flavoprotein domain 25 214 3.8E-41 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 163 183 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 PIRSF PIRSF000090 2 266 1.7E-81 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MSG_RS07630 327dcf6fb563a3ac8258e2a1de47af00 266 SUPERFAMILY SSF52402 3 260 1.88E-66 T 29-03-2018 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 SUPERFAMILY SSF75620 11 354 5.76E-121 T 29-03-2018 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 SMART SM00937 66 179 5.1E-46 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 Gene3D G3DSA:3.30.160.20 211 292 2.3E-31 T 29-03-2018 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 356 1.4E-150 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 Pfam PF03462 PCRF domain 13 204 7.3E-62 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 Gene3D G3DSA:1.20.58.410 3 96 8.7E-19 T 29-03-2018 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 357 35.177 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MSG_RS18300 7c76b8a2e3f4b8562389b8b28f91e793 357 Pfam PF00472 RF-1 domain 215 322 2.4E-39 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 Gene3D G3DSA:1.10.1740.10 2 123 1.5E-21 T 29-03-2018 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 174 5.7E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 49 80 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 SUPERFAMILY SSF88946 6 108 5.23E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 Pfam PF08281 Sigma-70, region 4 122 173 1.1E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 SUPERFAMILY SSF88659 118 175 4.58E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 Pfam PF04542 Sigma-70 region 2 28 93 3.6E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15605 b6e10787b1a9d864aa2c46ff2053d068 184 Gene3D G3DSA:1.10.10.10 124 183 1.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 Gene3D G3DSA:3.20.20.140 67 335 1.2E-96 T 29-03-2018 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 PIRSF PIRSF038994 32 384 1.1E-100 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 47 381 7.4E-74 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 Gene3D G3DSA:2.30.40.10 2 66 1.7E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 SUPERFAMILY SSF51338 355 383 1.06E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 SUPERFAMILY SSF51338 3 51 1.06E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 Gene3D G3DSA:2.30.40.10 336 380 1.4E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 Pfam PF01979 Amidohydrolase family 49 381 7.2E-30 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS05400 20e053f84fe40d5549c414c6e78c89b8 384 SUPERFAMILY SSF51556 52 353 4.93E-84 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 Gene3D G3DSA:3.40.50.720 120 279 2.3E-25 T 29-03-2018 MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 SUPERFAMILY SSF53223 12 111 5.07E-25 T 29-03-2018 MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 9 275 1.0E-98 T 29-03-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 Gene3D G3DSA:3.40.50.10860 3 119 1.9E-34 T 29-03-2018 MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 17 99 1.8E-19 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MSG_RS09895 783615c6a6b8ca8ba0d14930a51e3ff4 279 SUPERFAMILY SSF51735 128 276 1.51E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24025 dce24db46c26e670690866a2321d29f2 398 Gene3D G3DSA:3.40.640.10 28 277 7.0E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS24025 dce24db46c26e670690866a2321d29f2 398 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 394 7.2E-144 T 29-03-2018 IPR011340 Cysteine desulfurase-related MSG_RS24025 dce24db46c26e670690866a2321d29f2 398 SUPERFAMILY SSF53383 3 396 3.3E-55 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS24025 dce24db46c26e670690866a2321d29f2 398 Pfam PF00266 Aminotransferase class-V 21 390 1.1E-30 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS24025 dce24db46c26e670690866a2321d29f2 398 Gene3D G3DSA:3.90.1150.10 278 397 4.9E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 457 6.2E-160 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 SUPERFAMILY SSF52540 201 444 1.21E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 Gene3D G3DSA:1.10.860.10 16 167 9.5E-53 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 Pfam PF00772 DnaB-like helicase N terminal domain 23 125 1.1E-33 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 SMART SM00382 218 415 3.4E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 Gene3D G3DSA:3.40.50.300 183 458 1.7E-66 T 29-03-2018 MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 SUPERFAMILY SSF48024 22 133 1.57E-37 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MSG_RS00395 edb306b1cb42cd7d3d42978fd87a6a06 458 Pfam PF03796 DnaB-like helicase C terminal domain 201 455 2.0E-100 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MSG_RS09245 a1c53347e50020d3d5c6910b70bd52ee 384 Pfam PF13579 Glycosyl transferase 4-like domain 41 170 3.8E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS09245 a1c53347e50020d3d5c6910b70bd52ee 384 SUPERFAMILY SSF53756 23 359 1.75E-56 T 29-03-2018 MSG_RS09245 a1c53347e50020d3d5c6910b70bd52ee 384 Gene3D G3DSA:3.40.50.2000 185 346 1.3E-33 T 29-03-2018 MSG_RS09245 a1c53347e50020d3d5c6910b70bd52ee 384 Pfam PF00534 Glycosyl transferases group 1 189 339 2.5E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS09245 a1c53347e50020d3d5c6910b70bd52ee 384 Gene3D G3DSA:3.40.50.2000 4 184 2.9E-5 T 29-03-2018 MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 SUPERFAMILY SSF56601 295 691 1.24E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 SUPERFAMILY SSF56601 238 260 1.24E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 Pfam PF03793 PASTA domain 702 761 1.4E-8 T 29-03-2018 IPR005543 PASTA domain MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 630 2.1E-22 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 SMART SM00740 697 762 3.2E-11 T 29-03-2018 IPR005543 PASTA domain MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 Pfam PF00912 Transglycosylase 70 256 3.3E-53 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 SUPERFAMILY SSF53955 59 284 1.35E-59 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 Gene3D G3DSA:1.10.3810.10 62 273 6.4E-63 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MSG_RS23170 9d135474c61e4300de1cf3afd585493a 804 Gene3D G3DSA:3.40.710.10 287 731 7.2E-70 T 29-03-2018 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 SUPERFAMILY SSF48498 83 233 1.08E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 SUPERFAMILY SSF46689 12 77 2.77E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 Gene3D G3DSA:1.10.10.60 60 92 1.1E-6 T 29-03-2018 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 Gene3D G3DSA:1.10.357.10 93 249 5.2E-22 T 29-03-2018 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 Gene3D G3DSA:1.10.10.60 1 59 1.5E-13 T 29-03-2018 MSG_RS17970 4f41c622e5b62cc482dd7aef9ac8b403 263 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 224 1.3E-11 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 Gene3D G3DSA:3.40.50.300 1070 1250 6.7E-7 T 29-03-2018 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SUPERFAMILY SSF52540 435 706 4.04E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 Gene3D G3DSA:3.40.50.300 342 691 2.0E-21 T 29-03-2018 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 Gene3D G3DSA:3.40.50.300 719 1003 1.2E-8 T 29-03-2018 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SUPERFAMILY SSF52540 788 1007 2.41E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 Pfam PF01580 FtsK/SpoIIIE family 441 639 2.0E-18 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 Pfam PF01580 FtsK/SpoIIIE family 790 1039 3.9E-65 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 757 1311 1.3E-165 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SMART SM00382 1101 1274 0.023 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SMART SM00382 825 997 0.073 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SMART SM00382 471 661 1.4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 SUPERFAMILY SSF52540 1088 1265 5.14E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02370 9e579432a013892e92be3f451f8613d0 1327 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 709 9.9E-226 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS18370 69affc323fdf880f0c7375836b2735a2 188 SUPERFAMILY SSF69118 1 170 1.5E-18 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS18370 69affc323fdf880f0c7375836b2735a2 188 Gene3D G3DSA:1.20.1290.10 14 172 2.4E-13 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:3.40.50.980 604 768 5.8E-24 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:2.30.38.10 770 850 1.1E-20 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Pfam PF00501 AMP-binding enzyme 476 857 2.7E-75 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:3.30.300.30 852 968 5.2E-37 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:1.10.1200.10 969 1038 5.4E-15 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF52777 1231 1477 2.33E-15 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF52777 195 445 2.45E-42 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SMART SM01294 966 1029 0.0016 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF56801 434 976 1.24E-125 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:3.30.559.10 1039 1228 5.1E-18 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Pfam PF00550 Phosphopantetheine attachment site 967 1029 2.0E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Pfam PF00668 Condensation domain 13 447 1.5E-58 T 29-03-2018 IPR001242 Condensation domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Pfam PF00668 Condensation domain 1073 1360 3.0E-19 T 29-03-2018 IPR001242 Condensation domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:3.40.50.980 467 603 2.9E-35 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SMART SM00823 Phosphopantetheine attachment site 964 1033 3.7E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 497 880 7.9E-99 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 ProSitePatterns PS00455 Putative AMP-binding domain signature. 598 609 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF52777 11 209 1.07E-40 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Pfam PF13193 AMP-binding enzyme C-terminal domain 868 940 8.8E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 Gene3D G3DSA:3.30.559.10 2 211 1.4E-36 T 29-03-2018 MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF47336 958 1030 1.37E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16770 04fc30e8d947e4e9eebd94a8df1b8c4c 1478 SUPERFAMILY SSF52777 1049 1240 7.41E-24 T 29-03-2018 MSG_RS18820 13acdb1ec7c1ae41070d8f72f066cd04 309 Gene3D G3DSA:3.40.50.300 9 250 8.7E-54 T 29-03-2018 MSG_RS18820 13acdb1ec7c1ae41070d8f72f066cd04 309 SUPERFAMILY SSF52540 12 225 5.55E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18820 13acdb1ec7c1ae41070d8f72f066cd04 309 Pfam PF00005 ABC transporter 27 165 1.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18820 13acdb1ec7c1ae41070d8f72f066cd04 309 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18820 13acdb1ec7c1ae41070d8f72f066cd04 309 SMART SM00382 36 222 1.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Gene3D G3DSA:1.20.1580.10 92 499 1.1E-86 T 29-03-2018 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 951 22.965 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Pfam PF00005 ABC transporter 635 871 9.0E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Gene3D G3DSA:3.40.50.300 620 952 1.1E-55 T 29-03-2018 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Gene3D G3DSA:3.40.50.300 17 38 0.065 T 29-03-2018 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 Gene3D G3DSA:3.40.50.300 39 80 0.0019 T 29-03-2018 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 936 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 SUPERFAMILY SSF52540 626 925 1.7E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 SUPERFAMILY SSF52540 11 205 1.42E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11410 0bc2539c76d69a88f4190cce64f69658 971 SUPERFAMILY SSF52540 442 581 1.42E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SUPERFAMILY SSF47336 7 111 5.37E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1083 1098 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SUPERFAMILY SSF47336 1051 1126 4.97E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 ProSitePatterns PS00455 Putative AMP-binding domain signature. 692 703 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Pfam PF00501 AMP-binding enzyme 554 945 4.3E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:3.30.300.30 942 1064 1.6E-29 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:3.30.559.10 84 288 3.8E-21 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 575 969 8.1E-115 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SUPERFAMILY SSF52777 281 518 6.34E-41 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SMART SM00823 Phosphopantetheine attachment site 8 78 0.016 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SMART SM00823 Phosphopantetheine attachment site 1059 1129 0.018 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:2.30.38.10 859 936 6.3E-23 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:1.10.1200.10 2 83 6.9E-12 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Pfam PF00550 Phosphopantetheine attachment site 10 74 7.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Pfam PF00550 Phosphopantetheine attachment site 1061 1125 3.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SUPERFAMILY SSF56801 546 1072 8.37E-134 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 SUPERFAMILY SSF52777 96 265 3.34E-20 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:1.10.1200.10 1065 1131 1.6E-18 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:3.40.50.980 545 697 1.3E-36 T 29-03-2018 MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Pfam PF00668 Condensation domain 99 439 7.7E-22 T 29-03-2018 IPR001242 Condensation domain MSG_RS16795 8b1219c16700d9d9d78be0046ab74d41 1167 Gene3D G3DSA:3.40.50.980 698 855 2.0E-36 T 29-03-2018 MSG_RS06415 05d98b627af8504e53fff450d51742f7 156 Pfam PF01638 HxlR-like helix-turn-helix 22 109 3.7E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS06415 05d98b627af8504e53fff450d51742f7 156 Gene3D G3DSA:1.10.10.10 5 155 9.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06415 05d98b627af8504e53fff450d51742f7 156 SUPERFAMILY SSF46785 10 145 8.59E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24145 e6836775865a2505580ae53537e9b912 597 Gene3D G3DSA:1.20.140.10 304 472 4.3E-38 T 29-03-2018 MSG_RS24145 e6836775865a2505580ae53537e9b912 597 SUPERFAMILY SSF56645 132 301 3.66E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS24145 e6836775865a2505580ae53537e9b912 597 SUPERFAMILY SSF47203 312 465 4.35E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS24145 e6836775865a2505580ae53537e9b912 597 Gene3D G3DSA:2.40.110.10 190 293 3.6E-24 T 29-03-2018 MSG_RS24145 e6836775865a2505580ae53537e9b912 597 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 193 290 1.3E-15 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS24145 e6836775865a2505580ae53537e9b912 597 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 312 464 2.6E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS12895 ce019fc7c4f98be99b99114cdc73c055 216 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 210 1.1E-16 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS12895 ce019fc7c4f98be99b99114cdc73c055 216 Gene3D G3DSA:3.90.226.10 1 215 2.5E-34 T 29-03-2018 MSG_RS12895 ce019fc7c4f98be99b99114cdc73c055 216 SUPERFAMILY SSF52096 3 210 4.98E-35 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS05580 10ec748cdb8471accde8ba599af2e497 159 Gene3D G3DSA:3.10.490.10 2 154 6.6E-35 T 29-03-2018 MSG_RS05580 10ec748cdb8471accde8ba599af2e497 159 SUPERFAMILY SSF110857 3 125 1.7E-15 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like MSG_RS05580 10ec748cdb8471accde8ba599af2e497 159 Pfam PF13772 AIG2-like family 59 145 1.6E-24 T 29-03-2018 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 SMART SM00650 47 222 2.7E-68 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 31 296 47.738 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 Pfam PF00398 Ribosomal RNA adenine dimethylase 34 292 1.3E-37 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 Gene3D G3DSA:1.10.8.100 238 297 7.6E-16 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 Gene3D G3DSA:3.40.50.150 19 237 6.0E-48 T 29-03-2018 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 SUPERFAMILY SSF53335 31 295 1.4E-59 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 32 294 9.3E-79 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MSG_RS19935 cf582060894268ddd229db1f86bec5b5 317 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 63 90 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MSG_RS03180 76b3340aa7e9dbf16a22cfcb15399f81 290 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 1.0E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS03180 76b3340aa7e9dbf16a22cfcb15399f81 290 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 176 4.1E-36 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MSG_RS03180 76b3340aa7e9dbf16a22cfcb15399f81 290 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS15500 5273b997c2123048b93f058369e68116 446 Gene3D G3DSA:3.10.20.70 1 105 4.3E-32 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15500 5273b997c2123048b93f058369e68116 446 SUPERFAMILY SSF55931 108 445 9.81E-118 T 29-03-2018 MSG_RS15500 5273b997c2123048b93f058369e68116 446 SMART SM01230 106 357 2.0E-126 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15500 5273b997c2123048b93f058369e68116 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS15500 5273b997c2123048b93f058369e68116 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 444 1.2E-133 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15500 5273b997c2123048b93f058369e68116 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 3.9E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15500 5273b997c2123048b93f058369e68116 446 Gene3D G3DSA:3.30.590.10 106 446 5.5E-116 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS15500 5273b997c2123048b93f058369e68116 446 SUPERFAMILY SSF54368 7 104 6.15E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15500 5273b997c2123048b93f058369e68116 446 Pfam PF00120 Glutamine synthetase, catalytic domain 107 443 2.7E-127 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS08215 f7fa7fc2f0a1eb65f3d5cbf22f6f9bc7 321 SUPERFAMILY SSF56601 79 312 1.83E-17 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08215 f7fa7fc2f0a1eb65f3d5cbf22f6f9bc7 321 Gene3D G3DSA:3.40.710.10 75 317 2.2E-17 T 29-03-2018 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 ProSitePatterns PS01008 DnaA protein signature. 460 478 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Gene3D G3DSA:3.40.50.300 163 330 2.4E-21 T 29-03-2018 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 231 245 9.9E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 263 277 9.9E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 199 219 9.9E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 297 324 9.9E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 459 478 9.9E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 500 32.236 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Gene3D G3DSA:1.10.8.60 332 403 7.1E-26 T 29-03-2018 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 SMART SM00382 198 326 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 SUPERFAMILY SSF52540 165 377 1.4E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Gene3D G3DSA:1.10.1750.10 407 502 6.9E-33 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 43 499 1.2E-149 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Pfam PF00308 Bacterial dnaA protein 166 383 2.3E-103 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 SUPERFAMILY SSF48295 397 501 1.28E-30 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 413 478 7.7E-27 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MSG_RS00005 e471e76c5155350ef6f99fe1610ca57e 505 SMART SM00760 410 478 2.1E-31 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MSG_RS14210 1af27007c29631a0158bdbb06e1e8d96 272 Gene3D G3DSA:3.10.129.10 131 271 3.3E-14 T 29-03-2018 MSG_RS14210 1af27007c29631a0158bdbb06e1e8d96 272 Gene3D G3DSA:3.10.129.10 1 114 3.4E-16 T 29-03-2018 MSG_RS14210 1af27007c29631a0158bdbb06e1e8d96 272 SUPERFAMILY SSF54637 122 270 1.76E-23 T 29-03-2018 IPR029069 HotDog domain MSG_RS14210 1af27007c29631a0158bdbb06e1e8d96 272 SUPERFAMILY SSF54637 9 116 3.11E-10 T 29-03-2018 IPR029069 HotDog domain MSG_RS14210 1af27007c29631a0158bdbb06e1e8d96 272 Pfam PF13622 Thioesterase-like superfamily 27 269 1.3E-47 T 29-03-2018 MSG_RS05015 b71e05410b9ace121f17404eca1bd3ca 259 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 56 248 8.2E-46 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MSG_RS05015 b71e05410b9ace121f17404eca1bd3ca 259 Pfam PF00814 Glycoprotease family 87 196 1.7E-27 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05015 b71e05410b9ace121f17404eca1bd3ca 259 SUPERFAMILY SSF53067 160 232 2.07E-7 T 29-03-2018 MSG_RS05015 b71e05410b9ace121f17404eca1bd3ca 259 Gene3D G3DSA:3.30.420.40 42 188 8.9E-38 T 29-03-2018 MSG_RS05015 b71e05410b9ace121f17404eca1bd3ca 259 SUPERFAMILY SSF53067 55 154 1.04E-22 T 29-03-2018 MSG_RS01915 d3b59988918df95d95b2227a69d67687 428 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 59 365 6.2E-37 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MSG_RS01915 d3b59988918df95d95b2227a69d67687 428 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 66 373 2.4E-12 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MSG_RS05525 13cc7e0f169e434a16c9a234d4f47d5b 336 SUPERFAMILY SSF51182 69 331 1.93E-52 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS05525 13cc7e0f169e434a16c9a234d4f47d5b 336 Gene3D G3DSA:2.60.120.10 77 169 3.0E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS05525 13cc7e0f169e434a16c9a234d4f47d5b 336 Gene3D G3DSA:2.60.120.10 184 329 3.7E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS09670 980ff5324053fd3850308bb99885821a 356 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 37 339 4.9E-140 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 266 339 7.3E-29 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 266 340 1.0E-25 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 SUPERFAMILY SSF52540 33 263 4.53E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09670 980ff5324053fd3850308bb99885821a 356 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 327 343 3.4E-5 T 29-03-2018 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 72 91 3.4E-5 T 29-03-2018 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Gene3D G3DSA:1.10.8.60 197 267 3.1E-30 T 29-03-2018 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Gene3D G3DSA:3.40.50.300 31 194 9.5E-25 T 29-03-2018 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 SMART SM00382 64 197 2.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS09670 980ff5324053fd3850308bb99885821a 356 SUPERFAMILY SSF46785 269 343 1.32E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 23 248 4.4E-106 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 356 159.532 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MSG_RS09670 980ff5324053fd3850308bb99885821a 356 Gene3D G3DSA:1.10.10.10 270 340 4.0E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 SUPERFAMILY SSF81324 40 163 4.71E-22 T 29-03-2018 MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 Gene3D G3DSA:3.40.50.720 140 267 1.6E-25 T 29-03-2018 MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 SUPERFAMILY SSF51735 146 290 2.45E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 Pfam PF02254 TrkA-N domain 151 267 3.1E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 Gene3D G3DSA:1.10.287.70 38 139 7.4E-15 T 29-03-2018 MSG_RS06285 307091ec8b086cab96cea01eb26d1c3a 356 Pfam PF07885 Ion channel 47 129 1.6E-14 T 29-03-2018 IPR013099 Potassium channel domain MSG_RS15590 0e2d347d17cff7d0b555cfaab80648a9 312 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 90.045 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MSG_RS15590 0e2d347d17cff7d0b555cfaab80648a9 312 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 14 282 4.8E-51 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MSG_RS15590 0e2d347d17cff7d0b555cfaab80648a9 312 Pfam PF03186 CobD/Cbib protein 12 293 1.8E-85 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 Gene3D G3DSA:3.40.50.300 128 181 3.8E-8 T 29-03-2018 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 Gene3D G3DSA:3.40.50.300 1 127 4.0E-37 T 29-03-2018 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 Hamap MF_00235 Adenylate kinase [adk]. 1 180 44.293 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 PRINTS PR00094 Adenylate kinase signature 129 144 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 PRINTS PR00094 Adenylate kinase signature 81 97 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 PRINTS PR00094 Adenylate kinase signature 32 46 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 PRINTS PR00094 Adenylate kinase signature 4 17 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 PRINTS PR00094 Adenylate kinase signature 146 160 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 Pfam PF00406 Adenylate kinase 5 158 1.3E-52 T 29-03-2018 MSG_RS04700 9664be0cbb08a8c89f67d73a7b8bdf68 181 SUPERFAMILY SSF52540 2 180 1.15E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 SUPERFAMILY SSF116726 484 548 1.03E-7 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 SUPERFAMILY SSF51735 331 479 3.31E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 SUPERFAMILY SSF51735 10 125 3.94E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Gene3D G3DSA:3.30.70.1450 487 556 9.8E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Gene3D G3DSA:1.10.287.70 217 320 5.3E-12 T 29-03-2018 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Pfam PF07885 Ion channel 239 315 1.5E-11 T 29-03-2018 IPR013099 Potassium channel domain MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 SUPERFAMILY SSF81324 210 353 1.57E-18 T 29-03-2018 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Pfam PF02254 TrkA-N domain 23 93 3.9E-7 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Pfam PF02254 TrkA-N domain 336 451 2.0E-16 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Pfam PF02080 TrkA-C domain 492 547 6.6E-7 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Gene3D G3DSA:3.40.50.720 327 458 4.9E-18 T 29-03-2018 MSG_RS07010 803f7fa1270b4406e31dd4cadc401aef 592 Gene3D G3DSA:3.40.50.720 36 135 1.8E-9 T 29-03-2018 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 Gene3D G3DSA:3.90.660.10 200 389 3.8E-32 T 29-03-2018 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 SUPERFAMILY SSF54373 290 393 2.55E-25 T 29-03-2018 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 Pfam PF01593 Flavin containing amine oxidoreductase 16 444 4.3E-69 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 Gene3D G3DSA:1.10.405.10 108 199 3.5E-23 T 29-03-2018 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 373 392 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 425 442 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 8 27 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 174 195 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 197 219 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 394 416 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 PRINTS PR00757 Flavin-containing amine oxidase signature 293 312 3.0E-31 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 Gene3D G3DSA:3.50.50.60 2 102 9.9E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 Gene3D G3DSA:3.50.50.60 390 447 3.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 SUPERFAMILY SSF51905 407 446 1.68E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06635 bb76577a5dd41ea4061fe3cfe394aadc 447 SUPERFAMILY SSF51905 4 308 1.68E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 Gene3D G3DSA:1.10.357.10 72 225 3.4E-7 T 29-03-2018 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 SUPERFAMILY SSF48498 111 205 2.54E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 Gene3D G3DSA:1.10.260.40 44 71 0.0028 T 29-03-2018 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 109 196 6.3E-7 T 29-03-2018 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 1.1E-4 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 SUPERFAMILY SSF46689 9 87 8.72E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS12390 60681ee5d70e03e29d2a1a9f1d2e87cb 229 Gene3D G3DSA:1.10.10.60 6 43 1.2E-6 T 29-03-2018 MSG_RS16460 49c50d20d71c5926a864b08936c7679d 162 Gene3D G3DSA:1.10.287.100 116 147 7.0E-9 T 29-03-2018 MSG_RS16460 49c50d20d71c5926a864b08936c7679d 162 SUPERFAMILY SSF46785 20 145 5.62E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16460 49c50d20d71c5926a864b08936c7679d 162 Pfam PF01047 MarR family 40 97 1.3E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS16460 49c50d20d71c5926a864b08936c7679d 162 SMART SM00347 34 132 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS16460 49c50d20d71c5926a864b08936c7679d 162 Gene3D G3DSA:1.10.10.10 13 115 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 Gene3D G3DSA:3.40.50.720 135 314 1.1E-37 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 SUPERFAMILY SSF51905 152 316 1.53E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 2.3E-23 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 2.3E-23 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 2.3E-23 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.3E-23 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.3E-23 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 306 3.8E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 SUPERFAMILY SSF51905 10 197 1.64E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 Gene3D G3DSA:3.50.50.60 5 134 4.1E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 Pfam PF14759 Reductase C-terminal 327 395 5.6E-12 T 29-03-2018 IPR028202 Reductase, C-terminal MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 1.9E-14 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 1.9E-14 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.9E-14 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.9E-14 T 29-03-2018 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 Gene3D G3DSA:3.30.390.30 323 397 1.3E-19 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS04315 84757d5dcf1111ce859783d885ca48b9 399 SUPERFAMILY SSF55424 322 394 1.56E-17 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS21560 a16574536e6ab23764d882376601ac45 525 SUPERFAMILY SSF51703 4 519 9.68E-186 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS21560 a16574536e6ab23764d882376601ac45 525 Pfam PF01642 Methylmalonyl-CoA mutase 7 517 1.7E-197 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS21560 a16574536e6ab23764d882376601ac45 525 Gene3D G3DSA:3.20.20.240 5 519 4.8E-198 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS21560 a16574536e6ab23764d882376601ac45 525 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 6 522 2.3E-197 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 112 2.0E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 Gene3D G3DSA:1.10.540.10 1 115 2.4E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 Gene3D G3DSA:2.40.110.10 116 219 4.2E-8 T 29-03-2018 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 Gene3D G3DSA:1.20.140.10 220 345 1.7E-27 T 29-03-2018 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 SUPERFAMILY SSF56645 1 196 2.88E-30 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 SUPERFAMILY SSF47203 228 357 3.22E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16975 7f60d483c1852ae406f2483c562fb4cb 368 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 349 9.2E-22 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 SUPERFAMILY SSF51230 2 87 4.84E-25 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 SUPERFAMILY SSF47005 117 159 2.35E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Gene3D G3DSA:3.90.1170.30 48 89 0.02 T 29-03-2018 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Pfam PF02817 e3 binding domain 124 157 2.0E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Gene3D G3DSA:3.90.1170.30 1 47 2.2E-13 T 29-03-2018 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 175 394 1.9E-50 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 SUPERFAMILY SSF52777 177 394 3.07E-51 T 29-03-2018 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Pfam PF00364 Biotin-requiring enzyme 3 75 4.1E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Gene3D G3DSA:4.10.320.10 113 165 2.1E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MSG_RS13970 86d88577d068c663b1594748cceb93a0 396 Gene3D G3DSA:3.30.559.10 166 396 1.4E-53 T 29-03-2018 MSG_RS06970 22caf5330a75ed98abeeaef8fc3a6303 167 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 17 122 6.4E-11 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS06970 22caf5330a75ed98abeeaef8fc3a6303 167 SMART SM00701 1 116 2.1E-4 T 29-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS06970 22caf5330a75ed98abeeaef8fc3a6303 167 Gene3D G3DSA:3.40.80.10 1 140 4.4E-27 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS06970 22caf5330a75ed98abeeaef8fc3a6303 167 SUPERFAMILY SSF55846 14 131 1.96E-28 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS10015 4f552a0d56d04ad4133313a730c32af0 226 SUPERFAMILY SSF69336 15 195 2.62E-41 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS10015 4f552a0d56d04ad4133313a730c32af0 226 Pfam PF01493 GXGXG motif 17 188 1.1E-12 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS10015 4f552a0d56d04ad4133313a730c32af0 226 PIRSF PIRSF006519 1 226 4.9E-73 T 29-03-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein MSG_RS10015 4f552a0d56d04ad4133313a730c32af0 226 Gene3D G3DSA:2.160.20.60 7 200 1.5E-36 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 SUPERFAMILY SSF46785 22 149 7.52E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 Gene3D G3DSA:1.10.10.10 3 119 4.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 SMART SM00347 36 136 3.3E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 Pfam PF01047 MarR family 43 101 1.9E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 Gene3D G3DSA:1.10.287.100 120 150 4.5E-9 T 29-03-2018 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 3.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 3.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS00285 cb10193bea80c20d2d412f4da26eb2a2 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 3.1E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 Gene3D G3DSA:3.40.140.10 136 273 4.0E-54 T 29-03-2018 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 PIRSF PIRSF015626 2 273 2.6E-86 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 Gene3D G3DSA:3.10.20.10 28 120 4.5E-32 T 29-03-2018 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 Pfam PF02634 FdhD/NarQ family 26 272 1.1E-81 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 SUPERFAMILY SSF53927 5 272 2.53E-77 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 4.1E-49 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MSG_RS08245 0b67f066f6909e532a222c118a988a41 273 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 32.97 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 32 407 6.1E-162 T 29-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 21 405 28.706 T 29-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 SUPERFAMILY SSF55931 297 378 5.79E-46 T 29-03-2018 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 SUPERFAMILY SSF55931 40 259 5.79E-46 T 29-03-2018 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 46 351 1.8E-82 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS23355 7ccfc166edcf308122bd6b126ced3fb1 429 PIRSF PIRSF017901 1 427 1.4E-110 T 29-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 Gene3D G3DSA:1.10.340.30 17 109 1.3E-22 T 29-03-2018 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 SMART SM00525 178 198 1.1E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 SMART SM00478 30 177 9.0E-58 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 Pfam PF00633 Helix-hairpin-helix motif 91 118 3.6E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 179 195 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 160 1.1E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 Gene3D G3DSA:1.10.1670.10 110 209 3.2E-28 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 Hamap MF_00942 Endonuclease III [nth]. 1 201 34.997 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 SUPERFAMILY SSF48150 5 198 2.51E-62 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 PIRSF PIRSF001435 2 203 2.6E-44 T 29-03-2018 MSG_RS23125 ddaab82ef51fbc58b19f2da79fdc4bf4 226 TIGRFAM TIGR01083 nth: endonuclease III 4 186 9.8E-77 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MSG_RS13210 a0f721e9857063ee2bd8f9cb6fbfb172 328 SUPERFAMILY SSF53474 41 323 7.11E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13210 a0f721e9857063ee2bd8f9cb6fbfb172 328 Pfam PF00756 Putative esterase 55 317 2.9E-66 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS13210 a0f721e9857063ee2bd8f9cb6fbfb172 328 Gene3D G3DSA:3.40.50.1820 39 323 5.1E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12230 fccc09134bf08ca73fccfb03d6c631d7 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 94 1.8E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS12230 fccc09134bf08ca73fccfb03d6c631d7 141 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 7 135 6.4E-26 T 29-03-2018 IPR019920 F420-binding domain, putative MSG_RS12230 fccc09134bf08ca73fccfb03d6c631d7 141 SUPERFAMILY SSF50475 3 97 3.93E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS12230 fccc09134bf08ca73fccfb03d6c631d7 141 Gene3D G3DSA:2.30.110.10 1 107 2.8E-15 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 331 340 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 122 138 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 329 338 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 338 349 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 263 274 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 139 154 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 182 204 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 76 87 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 308 323 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 PRINTS PR00359 B-class P450 signature 280 307 6.8E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 SUPERFAMILY SSF48264 15 386 3.54E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 Gene3D G3DSA:1.10.630.10 3 387 5.3E-75 T 29-03-2018 MSG_RS15535 6cdc2f1b8b9fdf42a9c81b0c6dd0eba1 389 Pfam PF00067 Cytochrome P450 166 353 8.5E-28 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23285 2ae650846fb8237fefcfab8c5bbcaa05 218 Pfam PF13559 Domain of unknown function (DUF4129) 122 191 6.4E-15 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 PRINTS PR00773 GrpE protein signature 88 103 2.1E-22 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 PRINTS PR00773 GrpE protein signature 136 151 2.1E-22 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 PRINTS PR00773 GrpE protein signature 60 76 2.1E-22 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 PRINTS PR00773 GrpE protein signature 161 180 2.1E-22 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 Pfam PF01025 GrpE 51 181 4.1E-27 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 SUPERFAMILY SSF58014 46 125 9.29E-17 T 29-03-2018 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 Hamap MF_01151 Protein GrpE [grpE]. 2 182 14.845 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 SUPERFAMILY SSF51064 130 182 1.31E-12 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 Gene3D G3DSA:2.30.22.10 129 188 1.5E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 Gene3D G3DSA:3.90.20.20 40 128 1.3E-15 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MSG_RS02740 4ef778b1541585815eaeaadbc7e77064 209 ProSitePatterns PS01071 grpE protein signature. 139 180 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 SUPERFAMILY SSF51604 137 410 1.57E-48 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 Gene3D G3DSA:3.20.20.120 154 419 9.8E-43 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 SMART SM00922 168 280 6.7E-16 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 Gene3D G3DSA:3.30.390.10 25 153 7.2E-26 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 59 149 1.3E-7 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 SUPERFAMILY SSF54826 28 151 3.03E-19 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS01690 fc33a79ff14f4522e25c0300a75da486 423 Pfam PF13378 Enolase C-terminal domain-like 171 402 9.3E-33 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 SMART SM00387 268 380 3.9E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 Gene3D G3DSA:1.10.287.130 163 219 5.1E-12 T 29-03-2018 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 378 1.5E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 158 222 1.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 SUPERFAMILY SSF55874 213 379 6.94E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 SUPERFAMILY SSF47384 141 221 6.28E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 Gene3D G3DSA:3.30.450.20 48 162 1.3E-7 T 29-03-2018 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 SMART SM00388 157 223 8.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 319 7.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 7.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 7.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 333 7.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS03470 eba9fbc952f6d6944aafc5a4477dd9bc 409 Gene3D G3DSA:3.30.565.10 227 389 4.8E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 254 2.6E-68 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 Hamap MF_00258 Glutamate racemase [murI]. 6 258 37.319 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 SUPERFAMILY SSF53681 111 260 1.31E-39 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 SUPERFAMILY SSF53681 7 109 2.84E-33 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 2.3E-33 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 Gene3D G3DSA:3.40.50.1860 124 270 2.5E-45 T 29-03-2018 MSG_RS18080 a7c2b8c31aff093912f906f6a1ef1757 271 Gene3D G3DSA:3.40.50.1860 4 123 2.5E-27 T 29-03-2018 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 242 297 4.5E-21 T 29-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 SUPERFAMILY SSF88697 242 298 3.83E-14 T 29-03-2018 IPR015947 PUA-like domain MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 SUPERFAMILY SSF55120 13 229 7.2E-71 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 186 229 6.7E-12 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 13 224 1.3E-67 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 33 185 6.4E-50 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Gene3D G3DSA:2.30.130.10 235 296 8.4E-20 T 29-03-2018 IPR002478 PUA domain GO:0003723 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Gene3D G3DSA:3.30.2350.10 11 234 9.1E-79 T 29-03-2018 MSG_RS08595 b179ee3e4d87f543abdacf524b7739f9 301 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 296 17.265 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 SUPERFAMILY SSF47240 5 157 1.38E-42 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 PIRSF PIRSF005900 1 162 2.2E-55 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 63 79 4.9E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 39 55 4.9E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 134 152 4.9E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 ProSitePatterns PS00818 Dps protein family signature 1. 39 55 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 Gene3D G3DSA:1.20.1260.10 3 173 3.4E-48 T 29-03-2018 IPR012347 Ferritin-related MSG_RS01485 2658355e62c213c64064f214c997e2fb 183 Pfam PF00210 Ferritin-like domain 19 157 5.0E-29 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.6E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 Gene3D G3DSA:1.10.10.60 51 196 2.7E-11 T 29-03-2018 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 SUPERFAMILY SSF46689 2 77 3.22E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 Gene3D G3DSA:1.10.10.60 1 50 2.4E-18 T 29-03-2018 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05650 9b9a86a7837c49dabd0841355117cb11 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Gene3D G3DSA:3.20.20.70 450 802 6.0E-91 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Gene3D G3DSA:3.60.20.10 18 449 9.0E-167 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 SUPERFAMILY SSF69336 1240 1506 1.44E-90 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 SUPERFAMILY SSF56235 18 443 1.08E-148 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Pfam PF04898 Glutamate synthase central domain 466 757 5.2E-113 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Pfam PF01645 Conserved region in glutamate synthase 821 1190 8.8E-154 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Gene3D G3DSA:2.160.20.60 1246 1521 1.3E-110 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Gene3D G3DSA:3.20.20.70 803 1243 7.5E-160 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Pfam PF01493 GXGXG motif 1271 1457 1.1E-79 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 SUPERFAMILY SSF51395 457 1225 6.51E-265 T 29-03-2018 MSG_RS24425 4c0f7edc115e7617fd607fae8cb79fe1 1527 Pfam PF00310 Glutamine amidotransferases class-II 18 439 5.4E-182 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 Gene3D G3DSA:3.50.50.60 17 422 3.8E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 SUPERFAMILY SSF51905 17 213 2.07E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 SUPERFAMILY SSF51905 319 366 2.07E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 5.4E-5 T 29-03-2018 MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 338 5.4E-5 T 29-03-2018 MSG_RS15210 278125c5a433b2c524e35dc09ccf6ce3 481 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 5.4E-5 T 29-03-2018 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 Gene3D G3DSA:1.10.260.40 41 66 9.4E-14 T 29-03-2018 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 SUPERFAMILY SSF46689 6 85 3.49E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 Gene3D G3DSA:1.10.357.10 67 188 2.5E-10 T 29-03-2018 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 SUPERFAMILY SSF48498 84 187 4.78E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 Gene3D G3DSA:1.10.10.60 1 40 4.7E-14 T 29-03-2018 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03215 6bbac63438f4de142f807a900759dca8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 623 1.4E-236 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 1.8E-62 T 29-03-2018 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 1.1E-22 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 5.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 5.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 5.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 5.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MSG_RS06710 b0bfa954de99e2bf36056669b75b9695 629 Pfam PF00361 Proton-conducting membrane transporter 135 421 2.5E-83 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 SMART SM00562 2 136 5.6E-75 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 SUPERFAMILY SSF54919 2 135 2.36E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 1.1E-52 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 Gene3D G3DSA:3.30.70.141 56 135 1.1E-32 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 Gene3D G3DSA:3.30.70.141 1 55 3.4E-17 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 7.4E-43 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 7.4E-43 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 7.4E-43 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 7.4E-43 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 7.4E-43 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS17160 705e51b0fb0a33298268ec83e811e76e 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 33.656 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS10370 0b853a2c3226fb61f970a287fda9694e 159 SUPERFAMILY SSF52121 12 156 4.58E-51 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10370 0b853a2c3226fb61f970a287fda9694e 159 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 26.844 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10370 0b853a2c3226fb61f970a287fda9694e 159 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 150 7.7E-49 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10370 0b853a2c3226fb61f970a287fda9694e 159 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 149 7.0E-40 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10370 0b853a2c3226fb61f970a287fda9694e 159 Gene3D G3DSA:3.40.50.960 2 157 1.3E-56 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 SUPERFAMILY SSF56801 12 510 3.01E-96 T 29-03-2018 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 498 7.1E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Pfam PF00501 AMP-binding enzyme 17 412 2.4E-52 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Gene3D G3DSA:3.30.300.30 407 514 7.1E-18 T 29-03-2018 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Gene3D G3DSA:3.40.50.980 166 310 5.0E-30 T 29-03-2018 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Gene3D G3DSA:2.30.38.10 311 405 1.4E-15 T 29-03-2018 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 Gene3D G3DSA:3.40.50.980 7 165 1.9E-20 T 29-03-2018 MSG_RS12335 a715c48b02d981f24d97a63738673c2b 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS09310 88780428330334eb1e350ecc0b1007f9 58 SUPERFAMILY SSF46955 6 51 5.13E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS09310 88780428330334eb1e350ecc0b1007f9 58 Gene3D G3DSA:1.10.10.10 6 50 4.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09310 88780428330334eb1e350ecc0b1007f9 58 Pfam PF12728 Helix-turn-helix domain 6 49 8.8E-11 T 29-03-2018 MSG_RS09310 88780428330334eb1e350ecc0b1007f9 58 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 47 3.1E-12 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 Gene3D G3DSA:1.10.287.990 21 84 7.6E-18 T 29-03-2018 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PIRSF PIRSF000349 1 203 2.2E-75 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 SUPERFAMILY SSF46609 3 88 5.89E-30 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 SUPERFAMILY SSF54719 84 198 8.25E-44 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 9.8E-35 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 5.5E-31 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.2E-20 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.2E-20 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.2E-20 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.2E-20 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24330 1a5359fa633499c4c7e551aa015ede55 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.2E-20 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 SUPERFAMILY SSF88946 11 111 2.04E-28 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 Gene3D G3DSA:1.10.10.10 126 189 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 Gene3D G3DSA:1.10.1740.10 4 125 3.9E-25 T 29-03-2018 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 SUPERFAMILY SSF88659 115 178 7.41E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 Pfam PF04542 Sigma-70 region 2 31 97 1.9E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 176 3.9E-23 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24650 fddf153c3ce76eb552ad8cd9415607da 193 Pfam PF08281 Sigma-70, region 4 123 173 6.8E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS16205 d4eabb04b01f300022c7e61b106562ab 292 Gene3D G3DSA:3.40.47.10 154 289 1.0E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16205 d4eabb04b01f300022c7e61b106562ab 292 Gene3D G3DSA:3.40.47.10 6 153 4.9E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16205 d4eabb04b01f300022c7e61b106562ab 292 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 204 288 1.2E-7 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS16205 d4eabb04b01f300022c7e61b106562ab 292 SUPERFAMILY SSF53901 16 288 7.03E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:2.40.40.20 2 88 1.6E-14 T 29-03-2018 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SUPERFAMILY SSF52540 457 714 3.53E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:1.10.8.60 375 451 1.2E-15 T 29-03-2018 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:3.10.330.10 89 192 0.0022 T 29-03-2018 IPR029067 CDC48 domain 2-like MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 17 89 1.4E-11 T 29-03-2018 IPR003338 CDC48, N-terminal subdomain MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SMART SM00382 494 631 6.2E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SMART SM00382 243 365 0.87 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SMART SM01073 6 90 1.6E-13 T 29-03-2018 IPR003338 CDC48, N-terminal subdomain MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 ProSitePatterns PS00674 AAA-protein family signature. 599 617 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:1.10.8.60 637 721 1.6E-21 T 29-03-2018 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SUPERFAMILY SSF52540 205 439 2.4E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:3.40.50.300 203 374 1.5E-20 T 29-03-2018 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Gene3D G3DSA:3.40.50.300 452 636 1.1E-52 T 29-03-2018 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 498 628 9.7E-40 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 247 366 1.2E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS03175 1cab27f8f85a16e417927b598c5fd6e1 721 SUPERFAMILY SSF50692 17 88 6.33E-9 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 Pfam PF00108 Thiolase, N-terminal domain 5 272 1.2E-59 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 Gene3D G3DSA:3.40.47.10 1 276 4.4E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 Pfam PF02803 Thiolase, C-terminal domain 281 403 1.9E-49 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 402 6.3E-138 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 Gene3D G3DSA:3.40.47.10 277 401 2.2E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 SUPERFAMILY SSF53901 3 281 1.64E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 PIRSF PIRSF000429 1 405 8.9E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS19660 386254ca95f413ab987fa2b440cdb5c9 405 SUPERFAMILY SSF53901 282 403 7.37E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF07977 FabA-like domain 1250 1380 5.8E-35 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF07977 FabA-like domain 1641 1779 1.5E-35 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 497 693 8.6E-17 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 48 305 2.0E-45 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SMART SM00825 Beta-ketoacyl synthase 50 476 6.8E-59 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF54637 1638 1789 4.1E-31 T 29-03-2018 IPR029069 HotDog domain MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SMART SM00826 1803 1957 0.0083 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 313 426 9.3E-33 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF53901 451 472 8.49E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF53901 47 171 8.49E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF53901 201 422 8.49E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF54637 1213 1392 2.65E-29 T 29-03-2018 IPR029069 HotDog domain MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.10.129.10 1411 1600 1.5E-26 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.10.129.10 1005 1184 1.0E-21 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.10.129.10 1205 1393 1.9E-32 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.10.129.10 1635 1792 1.3E-31 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF53901 497 732 8.52E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Pfam PF14765 Polyketide synthase dehydratase 1808 2072 3.7E-16 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.40.47.10 489 736 3.0E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.40.47.10 45 317 1.5E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.40.1130.10 2234 2443 1.4E-6 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.40.47.10 318 474 9.3E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 Gene3D G3DSA:3.10.129.10 1804 1929 3.9E-6 T 29-03-2018 MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF54637 1038 1182 4.47E-19 T 29-03-2018 IPR029069 HotDog domain MSG_RS07995 057facc5f1293eb45c33d7e595622292 2514 SUPERFAMILY SSF54637 1417 1597 3.23E-20 T 29-03-2018 IPR029069 HotDog domain MSG_RS15540 ed54f69c05cda85de85857772fc01c8c 64 Gene3D G3DSA:3.30.70.20 1 64 2.8E-9 T 29-03-2018 MSG_RS15540 ed54f69c05cda85de85857772fc01c8c 64 Pfam PF13459 4Fe-4S single cluster domain 4 61 1.0E-11 T 29-03-2018 MSG_RS15540 ed54f69c05cda85de85857772fc01c8c 64 SUPERFAMILY SSF54862 2 63 7.86E-12 T 29-03-2018 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 463 1.1E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 Gene3D G3DSA:3.30.565.10 314 472 4.8E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 SUPERFAMILY SSF55874 300 463 1.06E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 311 2.4E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 SUPERFAMILY SSF47384 230 312 1.96E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 Gene3D G3DSA:1.10.287.130 228 307 8.7E-17 T 29-03-2018 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 Pfam PF00672 HAMP domain 176 232 5.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 SMART SM00387 354 465 1.1E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 SMART SM00304 175 237 5.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.9E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS23895 4b11a2b1e0e6cb35fbf7f2ae09e19919 477 SMART SM00388 245 311 7.2E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS23035 35667e613f05bf297d28641698439104 391 Gene3D G3DSA:3.40.50.300 186 377 2.5E-12 T 29-03-2018 MSG_RS23035 35667e613f05bf297d28641698439104 391 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 354 1.6E-153 T 29-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase MSG_RS23035 35667e613f05bf297d28641698439104 391 SUPERFAMILY SSF52540 43 347 7.55E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23035 35667e613f05bf297d28641698439104 391 Gene3D G3DSA:3.30.450.90 56 166 1.6E-28 T 29-03-2018 MSG_RS23035 35667e613f05bf297d28641698439104 391 Pfam PF00437 Type II/IV secretion system protein 62 339 1.8E-68 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MSG_RS23065 a02c48a25a54daccc6a51c5095664841 287 SUPERFAMILY SSF161098 78 266 6.67E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS23065 a02c48a25a54daccc6a51c5095664841 287 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 53 9.3E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MSG_RS23065 a02c48a25a54daccc6a51c5095664841 287 Gene3D G3DSA:1.10.3720.10 11 271 3.1E-40 T 29-03-2018 MSG_RS23065 a02c48a25a54daccc6a51c5095664841 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 282 6.9E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS22050 b7acc59a01a320bc1452a2713cd03cc2 138 SUPERFAMILY SSF54427 9 134 3.51E-20 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS22050 b7acc59a01a320bc1452a2713cd03cc2 138 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 11 131 4.2E-14 T 29-03-2018 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 MSG_RS22050 b7acc59a01a320bc1452a2713cd03cc2 138 Gene3D G3DSA:3.10.450.50 1 135 1.7E-16 T 29-03-2018 MSG_RS19995 c016e71e654d6b32d34a543a4fadba6d 347 Pfam PF13439 Glycosyltransferase Family 4 16 160 3.2E-11 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS19995 c016e71e654d6b32d34a543a4fadba6d 347 Gene3D G3DSA:3.40.50.2000 171 322 3.5E-11 T 29-03-2018 MSG_RS19995 c016e71e654d6b32d34a543a4fadba6d 347 Gene3D G3DSA:3.40.50.2000 8 170 6.0E-6 T 29-03-2018 MSG_RS19995 c016e71e654d6b32d34a543a4fadba6d 347 SUPERFAMILY SSF53756 12 341 1.15E-28 T 29-03-2018 MSG_RS16555 0786ad8302488fc5558ed145094eb0ef 282 Pfam PF02405 Permease MlaE 65 268 7.6E-51 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS14730 419fd21e80080f464b1cccedc8ce88c9 320 PIRSF PIRSF016838 1 320 2.5E-126 T 29-03-2018 IPR028349 Protein PafC MSG_RS14730 419fd21e80080f464b1cccedc8ce88c9 320 Gene3D G3DSA:1.10.10.10 2 62 9.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS14730 419fd21e80080f464b1cccedc8ce88c9 320 Pfam PF13280 WYL domain 145 312 7.8E-31 T 29-03-2018 IPR026881 WYL domain MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 Gene3D G3DSA:3.30.70.1020 219 293 4.7E-20 T 29-03-2018 MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 SUPERFAMILY SSF56784 137 374 2.75E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 136 374 6.1E-82 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 Gene3D G3DSA:3.40.50.1000 16 113 2.4E-7 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 Gene3D G3DSA:3.40.50.1000 122 201 0.0011 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 SUPERFAMILY SSF56784 47 108 8.93E-7 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 138 337 2.7E-18 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MSG_RS05215 bf8603ae829b29675b25da318c2da24f 381 Pfam PF02358 Trehalose-phosphatase 139 363 5.4E-70 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MSG_RS13640 eab874e4e8d8418b73dd588db554540f 246 SUPERFAMILY SSF53474 35 226 1.88E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13640 eab874e4e8d8418b73dd588db554540f 246 Pfam PF01083 Cutinase 35 225 5.8E-44 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS13640 eab874e4e8d8418b73dd588db554540f 246 Gene3D G3DSA:3.40.50.1820 31 230 6.4E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13640 eab874e4e8d8418b73dd588db554540f 246 SMART SM01110 34 226 1.2E-89 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Gene3D G3DSA:3.40.50.1000 170 416 1.3E-21 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Gene3D G3DSA:1.50.10.10 729 1131 3.8E-99 T 29-03-2018 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Gene3D G3DSA:2.60.420.10 1132 1204 1.3E-12 T 29-03-2018 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Gene3D G3DSA:3.40.50.1000 6 139 9.9E-4 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Gene3D G3DSA:2.70.98.40 417 683 9.8E-73 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 1150 1199 1.6E-11 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 SUPERFAMILY SSF48208 688 1187 7.14E-100 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 734 1146 7.8E-141 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 168 405 1.4E-65 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 172 372 4.1E-13 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 426 680 1.9E-64 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 Pfam PF02358 Trehalose-phosphatase 174 396 8.0E-59 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 SUPERFAMILY SSF74650 414 682 1.88E-65 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MSG_RS19355 75be8f3b9f8ad0ae529e571ee36888ec 1231 SUPERFAMILY SSF56784 172 407 1.46E-41 T 29-03-2018 IPR023214 HAD-like domain MSG_RS12770 b605f41819c30d9cd18c5f886256e742 233 SUPERFAMILY SSF48498 92 227 9.78E-31 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS12770 b605f41819c30d9cd18c5f886256e742 233 Gene3D G3DSA:1.10.10.60 9 62 1.5E-11 T 29-03-2018 MSG_RS12770 b605f41819c30d9cd18c5f886256e742 233 Gene3D G3DSA:1.10.357.10 63 232 2.2E-34 T 29-03-2018 MSG_RS12770 b605f41819c30d9cd18c5f886256e742 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 6.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12770 b605f41819c30d9cd18c5f886256e742 233 SUPERFAMILY SSF46689 10 80 1.35E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10790 070b2e1c591620f461254791681e3745 428 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 79 8.9E-10 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS10790 070b2e1c591620f461254791681e3745 428 SUPERFAMILY SSF53756 1 421 3.89E-91 T 29-03-2018 MSG_RS10790 070b2e1c591620f461254791681e3745 428 Gene3D G3DSA:3.40.50.2000 1 258 3.3E-36 T 29-03-2018 MSG_RS10790 070b2e1c591620f461254791681e3745 428 Gene3D G3DSA:3.40.50.2000 259 408 3.5E-27 T 29-03-2018 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Gene3D G3DSA:2.40.110.10 120 217 2.6E-34 T 29-03-2018 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 SUPERFAMILY SSF47203 230 370 4.19E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Gene3D G3DSA:1.20.140.10 218 373 7.1E-30 T 29-03-2018 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 2.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 SUPERFAMILY SSF56645 12 243 1.44E-60 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 119 4.6E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 368 6.9E-22 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS17730 7a811241096a28fdf67e447efa56c372 373 Gene3D G3DSA:1.10.540.10 1 119 1.6E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS03035 071956479d819d5a25be6ff6084ebc59 255 SUPERFAMILY SSF52266 2 254 5.16E-62 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS03035 071956479d819d5a25be6ff6084ebc59 255 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 246 2.1E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS03035 071956479d819d5a25be6ff6084ebc59 255 Gene3D G3DSA:3.40.50.1110 1 255 1.7E-24 T 29-03-2018 MSG_RS16890 6e544a23db53ba4ce54196ea5cfd75c2 348 Gene3D G3DSA:3.40.190.10 151 345 9.3E-41 T 29-03-2018 MSG_RS16890 6e544a23db53ba4ce54196ea5cfd75c2 348 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 68 338 9.6E-52 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MSG_RS16890 6e544a23db53ba4ce54196ea5cfd75c2 348 SUPERFAMILY SSF53850 47 344 4.78E-58 T 29-03-2018 MSG_RS16890 6e544a23db53ba4ce54196ea5cfd75c2 348 Gene3D G3DSA:3.40.190.10 49 150 2.0E-16 T 29-03-2018 MSG_RS16890 6e544a23db53ba4ce54196ea5cfd75c2 348 Pfam PF13531 Bacterial extracellular solute-binding protein 51 295 1.8E-32 T 29-03-2018 MSG_RS01635 d489ac37b1887d44592eac2611c021f1 221 Pfam PF04248 Domain of unknown function (DUF427) 123 209 1.1E-24 T 29-03-2018 IPR007361 Domain of unknown function DUF427 MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 SMART SM00346 12 99 9.5E-19 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 SUPERFAMILY SSF55781 67 244 3.73E-33 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 Pfam PF09339 IclR helix-turn-helix domain 15 63 2.3E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 Gene3D G3DSA:1.10.10.10 4 77 3.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 SUPERFAMILY SSF46785 15 82 2.13E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 Pfam PF01614 Bacterial transcriptional regulator 126 241 1.4E-21 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal MSG_RS12190 397c2c8462603bd8cc578e90a8e0eff1 276 Gene3D G3DSA:3.30.450.40 78 247 3.3E-37 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 Gene3D G3DSA:3.20.20.140 72 485 1.4E-42 T 29-03-2018 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 Gene3D G3DSA:2.30.40.10 2 71 6.2E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 SUPERFAMILY SSF51338 499 567 5.86E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 SUPERFAMILY SSF51338 3 57 5.86E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 Pfam PF07969 Amidohydrolase family 46 219 6.2E-9 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 Gene3D G3DSA:2.30.40.10 486 574 0.017 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 SUPERFAMILY SSF51556 365 497 2.4E-37 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS12495 a1590e5aac9b097ee8884d46c2f08abe 588 SUPERFAMILY SSF51556 58 317 2.4E-37 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS20455 6c94e0c6203758eabaa776c820e2c3d9 285 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 191 236 1.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS20455 6c94e0c6203758eabaa776c820e2c3d9 285 Pfam PF13419 Haloacid dehalogenase-like hydrolase 39 235 1.6E-7 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20455 6c94e0c6203758eabaa776c820e2c3d9 285 SUPERFAMILY SSF56784 15 68 8.62E-26 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20455 6c94e0c6203758eabaa776c820e2c3d9 285 SUPERFAMILY SSF56784 102 272 8.62E-26 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20455 6c94e0c6203758eabaa776c820e2c3d9 285 Gene3D G3DSA:3.40.50.1000 114 278 4.6E-17 T 29-03-2018 IPR023214 HAD-like domain MSG_RS17930 892b566c07bd098276b439d3464a7a62 287 Gene3D G3DSA:3.20.20.140 39 271 2.9E-36 T 29-03-2018 MSG_RS17930 892b566c07bd098276b439d3464a7a62 287 Pfam PF04909 Amidohydrolase 73 272 4.8E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS17930 892b566c07bd098276b439d3464a7a62 287 SUPERFAMILY SSF51556 30 271 2.95E-48 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS11285 8becb7b0f865999be5da824bbc91606a 484 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 459 3.6E-159 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MSG_RS11285 8becb7b0f865999be5da824bbc91606a 484 PIRSF PIRSF006446 1 481 7.1E-130 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 Gene3D G3DSA:1.10.10.60 52 70 2.6E-11 T 29-03-2018 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 SUPERFAMILY SSF48498 84 193 2.22E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 8.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 SUPERFAMILY SSF46689 5 88 5.64E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 Gene3D G3DSA:1.10.10.60 2 51 6.5E-18 T 29-03-2018 MSG_RS02155 ecf1b21d2634bdb5c088a2006748b33e 214 Gene3D G3DSA:1.10.357.10 71 197 3.1E-22 T 29-03-2018 MSG_RS21720 c37c683973feaf0854f762add3805c21 277 Gene3D G3DSA:3.40.250.10 1 141 2.9E-28 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 SUPERFAMILY SSF52821 3 139 3.4E-36 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 SMART SM00450 144 271 6.0E-24 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 SMART SM00450 8 122 7.4E-21 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 Gene3D G3DSA:3.40.250.10 153 277 4.3E-28 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 Pfam PF00581 Rhodanese-like domain 9 118 1.9E-16 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 Pfam PF00581 Rhodanese-like domain 149 266 3.7E-18 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 SUPERFAMILY SSF52821 149 275 8.12E-35 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS21720 c37c683973feaf0854f762add3805c21 277 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 SMART SM00100 10 128 4.2E-28 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 SUPERFAMILY SSF46785 145 223 1.87E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 Gene3D G3DSA:1.10.10.10 144 224 6.8E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 SUPERFAMILY SSF51206 4 142 7.07E-37 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 6.6E-24 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 Gene3D G3DSA:2.60.120.10 1 143 1.1E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 SMART SM00419 167 215 7.1E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MSG_RS23135 7c2a2bb7e4ff777934e778bfc0deb2ef 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.2E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MSG_RS24565 9699cb20948fa1f0d8a98f4e3c21735b 259 Gene3D G3DSA:3.40.50.300 1 233 3.3E-24 T 29-03-2018 MSG_RS24565 9699cb20948fa1f0d8a98f4e3c21735b 259 Pfam PF13469 Sulfotransferase family 3 194 1.2E-17 T 29-03-2018 MSG_RS24565 9699cb20948fa1f0d8a98f4e3c21735b 259 SUPERFAMILY SSF52540 3 200 2.25E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24310 54f8a34c4730fa26f13ccca561b08d11 227 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 23 135 9.0E-23 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS24310 54f8a34c4730fa26f13ccca561b08d11 227 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 24 134 5.5E-23 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 SUPERFAMILY SSF100879 241 338 9.22E-16 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Gene3D G3DSA:1.10.150.20 171 245 3.2E-16 T 29-03-2018 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Pfam PF00817 impB/mucB/samB family 9 153 1.8E-36 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 SUPERFAMILY SSF56672 4 235 4.71E-65 T 29-03-2018 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Pfam PF11799 impB/mucB/samB family C-terminal domain 242 339 1.1E-6 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Pfam PF11798 IMS family HHH motif 167 197 1.5E-5 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Gene3D G3DSA:3.30.1490.100 246 344 1.8E-15 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Gene3D G3DSA:3.30.70.270 119 170 2.7E-15 T 29-03-2018 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Gene3D G3DSA:3.30.70.270 46 118 1.5E-15 T 29-03-2018 MSG_RS07325 ec1b74de32f028e558d3d1a15695c29e 344 Hamap MF_01113 DNA polymerase IV [dinB]. 3 342 28.036 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PIRSF PIRSF006648 7 248 8.6E-58 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 Pfam PF01061 ABC-2 type transporter 11 215 1.6E-35 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 1.2E-11 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 75 1.2E-11 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 1.2E-11 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.2E-11 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS01265 febd69bc7f470a8187b37914524f26cc 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 1.2E-11 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Gene3D G3DSA:2.40.110.10 146 250 5.3E-29 T 29-03-2018 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 SUPERFAMILY SSF56645 84 262 3.93E-52 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 SUPERFAMILY SSF56645 2 57 3.93E-52 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 267 415 2.9E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Gene3D G3DSA:1.10.540.10 1 145 2.3E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 251 8.4E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 141 1.8E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 Gene3D G3DSA:1.20.140.10 251 418 2.0E-43 T 29-03-2018 MSG_RS08610 d0372f35d43886010a99215ca60e1291 418 SUPERFAMILY SSF47203 268 416 4.83E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 SUPERFAMILY SSF46785 1 85 1.63E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 Gene3D G3DSA:1.10.10.10 1 83 3.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 SUPERFAMILY SSF53850 97 270 7.42E-5 T 29-03-2018 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.0E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00975 5a8fba7b4704760e58c0af4a0c634628 318 Gene3D G3DSA:3.40.190.10 91 196 1.7E-5 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 325 2.7E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 464 7.7E-164 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 3.5E-65 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 453 2.2E-34 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 Gene3D G3DSA:3.50.50.60 1 158 6.3E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 SUPERFAMILY SSF51905 3 368 1.44E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PIRSF PIRSF000350 1 460 7.6E-88 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 3.5E-34 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 3.5E-34 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-34 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 3.5E-34 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 3.5E-34 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 Gene3D G3DSA:3.40.50.720 159 331 2.7E-36 T 29-03-2018 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 Gene3D G3DSA:3.30.390.30 332 461 2.0E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS03340 553a64a7a7dc1ef392883866f180b246 465 SUPERFAMILY SSF55424 342 464 8.25E-38 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS17860 e65c76c6791403ca327319c0389cc82f 381 Gene3D G3DSA:3.40.50.1820 134 378 1.8E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17860 e65c76c6791403ca327319c0389cc82f 381 Pfam PF10503 Esterase PHB depolymerase 148 263 5.5E-5 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 MSG_RS17860 e65c76c6791403ca327319c0389cc82f 381 SUPERFAMILY SSF53474 137 354 7.6E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 131 5.6E-49 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 Gene3D G3DSA:2.40.50.100 6 132 4.8E-45 T 29-03-2018 MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 SUPERFAMILY SSF51230 4 130 6.67E-41 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 131 39.341 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MSG_RS12820 8c5c5173885a958bab860101ee70cf88 132 Pfam PF01597 Glycine cleavage H-protein 8 130 1.0E-42 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Gene3D G3DSA:2.40.110.10 124 221 2.5E-31 T 29-03-2018 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 SUPERFAMILY SSF47203 250 401 1.93E-56 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 114 1.1E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 SUPERFAMILY SSF56645 3 234 1.31E-56 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 222 2.1E-23 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 397 3.1E-52 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Gene3D G3DSA:1.10.540.10 1 116 1.6E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 Gene3D G3DSA:1.20.140.10 222 403 1.0E-57 T 29-03-2018 MSG_RS00690 68795b03909315502e9eb61de365e9ea 403 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 356 375 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS23320 59e9ed1c3dac290d07f1909eaa8033f2 238 Gene3D G3DSA:1.10.10.10 87 189 5.0E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23320 59e9ed1c3dac290d07f1909eaa8033f2 238 Pfam PF03551 Transcriptional regulator PadR-like family 104 173 2.6E-22 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal MSG_RS23320 59e9ed1c3dac290d07f1909eaa8033f2 238 SUPERFAMILY SSF46785 90 187 3.44E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 SUPERFAMILY SSF47203 240 396 3.54E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 225 2.0E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 SUPERFAMILY SSF56645 4 235 2.36E-49 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 394 9.9E-36 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Gene3D G3DSA:2.40.110.10 133 229 3.4E-36 T 29-03-2018 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Gene3D G3DSA:1.20.140.10 230 402 1.0E-40 T 29-03-2018 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 124 1.1E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06835 f6de8fceff0ff3c81987cc059e38148d 402 Gene3D G3DSA:1.10.540.10 1 132 1.6E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 Gene3D G3DSA:1.10.260.40 42 70 2.9E-13 T 29-03-2018 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 Gene3D G3DSA:1.10.10.60 6 41 1.6E-10 T 29-03-2018 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 SUPERFAMILY SSF46689 15 85 1.15E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 Gene3D G3DSA:1.10.357.10 71 199 7.0E-8 T 29-03-2018 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.2E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 5.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01025 511e8c47c275d2c38723cb3aa953aaaf 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 5.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24050 ad58e50253aac9b1784258492bd4b378 276 Pfam PF01061 ABC-2 type transporter 29 237 4.0E-25 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 Pfam PF00106 short chain dehydrogenase 8 207 6.0E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 3.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 Gene3D G3DSA:3.40.50.720 2 267 1.6E-63 T 29-03-2018 MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 SUPERFAMILY SSF51735 3 261 1.21E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 1.9E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02585 a0c843c52a89fa987f2322abc0cc94ad 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS21600 4168c76da9582c5bbed0abcf67259882 349 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 257 340 6.5E-10 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS21600 4168c76da9582c5bbed0abcf67259882 349 Gene3D G3DSA:3.40.47.10 182 344 1.4E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21600 4168c76da9582c5bbed0abcf67259882 349 SUPERFAMILY SSF53901 3 343 5.63E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21600 4168c76da9582c5bbed0abcf67259882 349 Gene3D G3DSA:3.40.47.10 4 181 2.3E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21600 4168c76da9582c5bbed0abcf67259882 349 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 202 3.8E-11 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 SUPERFAMILY SSF56801 10 533 3.27E-139 T 29-03-2018 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Gene3D G3DSA:2.30.38.10 346 430 4.7E-18 T 29-03-2018 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Gene3D G3DSA:3.40.50.980 188 345 2.7E-43 T 29-03-2018 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Gene3D G3DSA:3.30.300.30 431 537 4.0E-26 T 29-03-2018 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Pfam PF00501 AMP-binding enzyme 30 437 8.8E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Gene3D G3DSA:3.40.50.980 9 187 3.7E-34 T 29-03-2018 MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS19715 8b42b3bbfe8cf2fc213f2e109c4f1385 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 6.9E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS06190 f8c1b7ade870f102f4020f04b5f1efa1 322 Gene3D G3DSA:3.40.50.10330 1 125 1.4E-27 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MSG_RS06190 f8c1b7ade870f102f4020f04b5f1efa1 322 SUPERFAMILY SSF111331 1 318 5.45E-50 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MSG_RS06190 f8c1b7ade870f102f4020f04b5f1efa1 322 SMART SM00046 2 131 8.1E-23 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS06190 f8c1b7ade870f102f4020f04b5f1efa1 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 120 5.6E-26 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 492 7.9E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 Gene3D G3DSA:1.10.8.60 486 599 6.8E-5 T 29-03-2018 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 SMART SM00382 356 495 1.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 50 602 3.0E-252 T 29-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 Gene3D G3DSA:1.25.40.10 42 270 4.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 397 411 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 442 454 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 359 374 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 480 499 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 463 480 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 319 333 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 411 430 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 PRINTS PR00819 CbxX/CfqX superfamily signature 550 562 4.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 SUPERFAMILY SSF52540 316 530 5.35E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02360 00d7ca19eb8677895da37ae617872c7e 610 Gene3D G3DSA:3.40.50.300 298 485 1.5E-25 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.40.366.10 566 698 7.3E-33 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 201 217 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF53901 184 411 2.81E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF53901 33 157 2.81E-104 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.40.47.10 27 300 2.7E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF52151 567 692 2.09E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF52151 755 852 2.09E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2082 2097 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1787 1966 1.2E-38 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 869 2.4E-85 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 425 521 2.0E-12 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF00698 Acyl transferase domain 568 886 2.4E-104 T 29-03-2018 IPR014043 Acyl transferase MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF08659 KR domain 1787 1965 2.2E-59 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF13602 Zinc-binding dehydrogenase 1624 1763 2.3E-21 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.40.47.10 303 463 4.6E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00825 Beta-ketoacyl synthase 37 465 1.2E-211 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF00550 Phosphopantetheine attachment site 2060 2121 4.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF55048 690 752 1.29E-7 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF50129 1446 1581 8.02E-31 T 29-03-2018 IPR011032 GroES-like MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00826 925 1085 1.2E-36 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00829 1452 1763 3.0E-153 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.10.129.10 932 1050 4.8E-8 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF51735 1557 1723 7.23E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.90.180.10 1445 1766 5.4E-67 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF51735 1787 2003 2.27E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 412 3.3E-43 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.40.50.720 1783 2033 1.1E-43 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SMART SM00823 Phosphopantetheine attachment site 2057 2127 2.1E-18 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 288 1.5E-93 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF47336 2055 2140 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.30.70.250 699 745 7.1E-13 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 SUPERFAMILY SSF51735 1214 1420 1.14E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1469 1529 6.1E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Pfam PF14765 Polyketide synthase dehydratase 925 1208 4.8E-52 T 29-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:1.10.1200.10 2036 2128 5.8E-18 T 29-03-2018 MSG_RS08050 4aa9776b93b7cfd4eb23a0985b22870b 2176 Gene3D G3DSA:3.40.366.10 746 861 1.7E-20 T 29-03-2018 MSG_RS23270 021c51480adc96dd1b15f6187793a5a6 328 SUPERFAMILY SSF51679 1 313 2.65E-60 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS23270 021c51480adc96dd1b15f6187793a5a6 328 Gene3D G3DSA:3.20.20.30 2 325 1.6E-51 T 29-03-2018 MSG_RS23270 021c51480adc96dd1b15f6187793a5a6 328 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 325 2.9E-151 T 29-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related MSG_RS23270 021c51480adc96dd1b15f6187793a5a6 328 Pfam PF00296 Luciferase-like monooxygenase 3 296 3.6E-46 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 Pfam PF08031 Berberine and berberine like 439 471 6.0E-6 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 Gene3D G3DSA:3.30.43.10 32 123 2.2E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 Gene3D G3DSA:3.30.465.10 130 269 1.6E-33 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 Pfam PF01565 FAD binding domain 75 210 7.4E-30 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 75 108 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MSG_RS04545 fae7f6931803a44d0f7123cf3572d793 479 SUPERFAMILY SSF56176 37 243 1.21E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SMART SM00954 293 403 7.7E-60 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Pfam PF02824 TGS domain 452 511 3.9E-23 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Pfam PF13328 HD domain 86 233 4.0E-46 T 29-03-2018 IPR003607 HD/PDEase domain MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Gene3D G3DSA:3.30.460.10 250 383 1.2E-41 T 29-03-2018 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SUPERFAMILY SSF109604 61 249 3.77E-69 T 29-03-2018 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SUPERFAMILY SSF81301 238 456 1.23E-59 T 29-03-2018 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Pfam PF04607 Region found in RelA / SpoT proteins 293 402 4.1E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 86 785 9.6E-279 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SUPERFAMILY SSF55021 708 788 1.5E-14 T 29-03-2018 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Pfam PF13291 ACT domain 709 785 2.8E-16 T 29-03-2018 IPR002912 ACT domain MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SMART SM00471 101 211 1.2E-13 T 29-03-2018 IPR003607 HD/PDEase domain MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Gene3D G3DSA:3.30.70.260 713 790 4.1E-13 T 29-03-2018 MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 Gene3D G3DSA:3.10.20.30 446 518 9.8E-27 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS09720 77495db64b8110b70586ab4f5841e43e 790 SUPERFAMILY SSF81271 439 511 7.52E-22 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 Gene3D G3DSA:1.10.10.60 11 66 1.6E-18 T 29-03-2018 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 SUPERFAMILY SSF46689 11 71 9.22E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 100 192 2.3E-6 T 29-03-2018 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 SUPERFAMILY SSF48498 85 194 1.48E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21280 8ccc5fe8efd41fed656a5c960a64f6d3 205 Gene3D G3DSA:1.10.357.10 67 205 1.0E-15 T 29-03-2018 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 2 202 9.4E-64 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 2 296 2.7E-84 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 296 2.7E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 SUPERFAMILY SSF53850 2 210 7.24E-62 T 29-03-2018 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 PIRSF PIRSF001438 1 312 1.2E-102 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 PRINTS PR00151 Porphobilinogen deaminase signature 68 87 3.4E-23 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 3.4E-23 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 3.4E-23 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 3.4E-23 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Gene3D G3DSA:3.40.190.10 1 98 2.9E-30 T 29-03-2018 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Gene3D G3DSA:3.30.160.40 213 305 1.4E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Gene3D G3DSA:3.40.190.10 99 191 3.6E-32 T 29-03-2018 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 1 298 33.955 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03595 468347ded00a64a28150c55e99ab7d43 315 SUPERFAMILY SSF54782 212 307 4.32E-20 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 471 482 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 SUPERFAMILY SSF52016 385 562 1.41E-54 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 21 561 5.6E-216 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 Pfam PF00920 Dehydratase family 37 560 2.9E-208 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 SUPERFAMILY SSF143975 4 384 1.57E-137 T 29-03-2018 MSG_RS01855 01d465aef97b5825d0dc4ee2593c88c2 563 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 7 563 45.678 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 Pfam PF00665 Integrase core domain 154 309 2.7E-40 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:3.30.420.10 148 358 4.0E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF53098 211 352 5.69E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF53098 158 168 5.69E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS08700 2cbdb787e351ab4cb888aa49b54d3aa6 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 Pfam PF00665 Integrase core domain 154 309 2.7E-40 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:3.30.420.10 148 358 4.0E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF53098 211 352 5.69E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF53098 158 168 5.69E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17410 2cbdb787e351ab4cb888aa49b54d3aa6 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 Gene3D G3DSA:3.40.630.10 10 218 1.7E-43 T 29-03-2018 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 SUPERFAMILY SSF53187 364 453 1.29E-56 T 29-03-2018 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 SUPERFAMILY SSF53187 14 200 1.29E-56 T 29-03-2018 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 Pfam PF01546 Peptidase family M20/M25/M40 91 452 5.0E-36 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 Pfam PF07687 Peptidase dimerisation domain 212 340 2.2E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 90 99 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 Gene3D G3DSA:3.30.70.360 219 355 1.6E-22 T 29-03-2018 MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 SUPERFAMILY SSF55031 303 339 8.37E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS14965 a6f8a68577ebe526db411093ec260368 454 SUPERFAMILY SSF55031 215 257 8.37E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF47336 908 986 4.19E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Pfam PF08659 KR domain 659 830 3.3E-33 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Pfam PF00550 Phosphopantetheine attachment site 913 979 5.4E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 103 394 2.0E-66 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 ProSitePatterns PS00012 Phosphopantetheine attachment site. 938 953 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Gene3D G3DSA:3.40.366.10 280 402 3.5E-17 T 29-03-2018 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Gene3D G3DSA:3.40.50.720 655 867 1.1E-31 T 29-03-2018 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Pfam PF00698 Acyl transferase domain 102 396 1.1E-47 T 29-03-2018 IPR014043 Acyl transferase MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Gene3D G3DSA:3.30.70.250 240 279 2.3E-13 T 29-03-2018 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF51735 658 867 6.54E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 657 832 8.0E-12 T 29-03-2018 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF52151 290 384 3.14E-48 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF52151 99 226 3.14E-48 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Gene3D G3DSA:3.40.366.10 96 239 8.3E-29 T 29-03-2018 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SMART SM00823 Phosphopantetheine attachment site 911 983 5.0E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF51735 463 630 9.84E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 SUPERFAMILY SSF55048 226 289 5.75E-11 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS16780 d34fc4f0a6b77026817a843b3d0af57f 996 Gene3D G3DSA:1.10.1200.10 894 989 7.8E-14 T 29-03-2018 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 Gene3D G3DSA:3.40.50.10730 190 320 1.3E-19 T 29-03-2018 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 Gene3D G3DSA:3.90.180.10 1 189 1.2E-44 T 29-03-2018 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 162 2.0E-23 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 1 377 2.1E-146 T 29-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 SUPERFAMILY SSF50129 1 200 9.13E-50 T 29-03-2018 IPR011032 GroES-like MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 SUPERFAMILY SSF50129 328 376 3.06E-8 T 29-03-2018 IPR011032 GroES-like MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 SUPERFAMILY SSF51735 166 341 5.85E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 SMART SM00829 6 375 6.2E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS01100 b79f3c9d011c8d91aff87bdbdb983426 380 Pfam PF00107 Zinc-binding dehydrogenase 204 325 9.4E-16 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS24445 fb48e3723a9d07376c19005c488cbeb6 147 Pfam PF04075 F420H(2)-dependent quinone reductase 25 100 1.7E-6 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS24445 fb48e3723a9d07376c19005c488cbeb6 147 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 111 3.6E-14 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS24445 fb48e3723a9d07376c19005c488cbeb6 147 SUPERFAMILY SSF50475 29 144 2.88E-5 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS24445 fb48e3723a9d07376c19005c488cbeb6 147 Gene3D G3DSA:2.30.110.10 17 146 1.2E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS24095 100e61772cd76465e8ab1b4ba927b2a2 648 Pfam PF12250 Arabinofuranosyltransferase N terminal 10 461 4.8E-161 T 29-03-2018 IPR020963 Arabinofuranosyltransferase AftA, N-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 MSG_RS24095 100e61772cd76465e8ab1b4ba927b2a2 648 Pfam PF12249 Arabinofuranosyltransferase A C terminal 472 644 8.6E-73 T 29-03-2018 IPR020959 Arabinofuranosyltransferase AftA, C-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1091 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF52335 975 1111 6.54E-35 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.30.1490.20 673 762 1.8E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 5.7E-37 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF56059 691 966 4.95E-95 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.40.50.20 541 672 1.1E-57 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.40.50.20 4 122 1.3E-31 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.30.470.20 763 966 1.0E-34 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SMART SM00851 988 1081 1.9E-25 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 339 8.2E-65 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 691 893 6.2E-34 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 856 863 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SMART SM01096 426 549 1.8E-58 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.40.50.1380 967 1113 7.7E-46 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:3.30.470.20 125 407 8.3E-63 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Pfam PF02142 MGS-like domain 989 1081 3.2E-22 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 727 741 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF56059 133 405 4.07E-100 T 29-03-2018 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1102 12.751 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF52440 563 692 3.45E-43 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF48108 401 552 2.35E-40 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 SUPERFAMILY SSF52440 2 132 1.87E-40 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 209 228 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 244 261 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 302 331 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 384 402 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 173 185 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.9E-60 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 Gene3D G3DSA:1.10.1030.10 410 540 8.3E-41 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10240 76b4d2a8e1bff07ee22540d352b3fda8 1120 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 302 309 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS06675 4d2482b00a70ee8037252cbb2f030fd9 314 Pfam PF13559 Domain of unknown function (DUF4129) 234 302 6.1E-9 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 Gene3D G3DSA:3.40.50.720 73 206 1.0E-4 T 29-03-2018 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 351 379 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 Gene3D G3DSA:3.40.50.720 250 456 9.2E-52 T 29-03-2018 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 Gene3D G3DSA:3.40.50.720 210 249 6.0E-9 T 29-03-2018 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 291 302 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 418 438 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 338 354 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 364 383 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 385 402 1.2E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 224 452 2.3E-49 T 29-03-2018 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 SUPERFAMILY SSF51735 214 455 6.76E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 218 395 5.6E-4 T 29-03-2018 MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 344 352 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 364 383 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02170 4aae53d028cfe763d0873518a2c75521 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 291 302 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 SUPERFAMILY SSF48498 87 195 2.0E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 193 1.7E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 Gene3D G3DSA:1.10.10.60 4 66 1.5E-12 T 29-03-2018 MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 Gene3D G3DSA:1.10.357.10 67 195 1.5E-12 T 29-03-2018 MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 9.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19105 8ced50254b4c514822181a2826b23b82 210 SUPERFAMILY SSF46689 14 75 3.03E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Pfam PF12826 Helix-hairpin-helix motif 527 590 3.3E-21 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 331 408 3.5E-30 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SUPERFAMILY SSF50249 328 410 2.74E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 13 328 3.6E-124 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:3.30.1490.70 249 331 3.5E-27 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SMART SM00532 12 459 3.3E-265 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:3.30.470.30 127 248 5.6E-47 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SUPERFAMILY SSF47781 413 600 4.45E-51 T 29-03-2018 IPR010994 RuvA domain 2-like MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SUPERFAMILY SSF56091 11 326 7.74E-112 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SMART SM00292 609 686 4.4E-12 T 29-03-2018 IPR001357 BRCT domain MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:3.40.50.10190 589 686 1.3E-19 T 29-03-2018 IPR001357 BRCT domain MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 445 5.1E-9 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 PIRSF PIRSF001604 7 687 7.0E-233 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:1.10.150.20 443 522 8.0E-23 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Hamap MF_01588 DNA ligase [ligA]. 11 683 51.716 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:2.40.50.140 332 399 1.7E-27 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 609 681 2.5E-12 T 29-03-2018 IPR001357 BRCT domain MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:1.10.150.20 523 588 6.6E-28 T 29-03-2018 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 678 1.0E-243 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 SUPERFAMILY SSF52113 611 686 6.54E-18 T 29-03-2018 IPR001357 BRCT domain MSG_RS07675 f41c96bc1bd67302f3f1cb26f39c8165 691 Gene3D G3DSA:1.10.287.610 3 76 3.5E-28 T 29-03-2018 MSG_RS10410 29538266b113256753884fd989bb25ab 454 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 304 373 6.7E-10 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS10410 29538266b113256753884fd989bb25ab 454 SUPERFAMILY SSF140459 5 176 3.66E-56 T 29-03-2018 MSG_RS10410 29538266b113256753884fd989bb25ab 454 Gene3D G3DSA:1.10.287.1060 24 108 1.2E-7 T 29-03-2018 MSG_RS10410 29538266b113256753884fd989bb25ab 454 Pfam PF00823 PPE family 8 164 3.3E-57 T 29-03-2018 IPR000030 PPE family MSG_RS22155 3a53c400bfefd4a8e0447d1beb40ae86 256 Gene3D G3DSA:3.90.226.10 1 256 5.5E-66 T 29-03-2018 MSG_RS22155 3a53c400bfefd4a8e0447d1beb40ae86 256 SUPERFAMILY SSF52096 3 256 8.85E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS22155 3a53c400bfefd4a8e0447d1beb40ae86 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 255 3.2E-44 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS22155 3a53c400bfefd4a8e0447d1beb40ae86 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS16255 d17d65f2646891829a4dd0b8b72f3708 469 SUPERFAMILY SSF53720 3 468 2.09E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS16255 d17d65f2646891829a4dd0b8b72f3708 469 Pfam PF00171 Aldehyde dehydrogenase family 4 465 3.7E-178 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS16255 d17d65f2646891829a4dd0b8b72f3708 469 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS16255 d17d65f2646891829a4dd0b8b72f3708 469 Gene3D G3DSA:3.40.309.10 258 451 1.1E-67 T 29-03-2018 MSG_RS16255 d17d65f2646891829a4dd0b8b72f3708 469 Gene3D G3DSA:3.40.605.10 1 257 3.9E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS11575 5f7600207b477049da612b9d781770fe 102 SUPERFAMILY SSF140459 7 71 4.97E-11 T 29-03-2018 MSG_RS11575 5f7600207b477049da612b9d781770fe 102 Pfam PF00934 PE family 3 92 1.1E-17 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS11575 5f7600207b477049da612b9d781770fe 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 33 90 1.0E-10 T 29-03-2018 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Gene3D G3DSA:1.20.50.20 376 429 3.5E-21 T 29-03-2018 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Pfam PF13662 Toprim domain 264 334 3.0E-13 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Pfam PF01807 CHC2 zinc finger 6 100 5.1E-35 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 SMART SM00766 486 615 1.9E-30 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Hamap MF_00974 DNA primase [dnaG]. 4 620 25.738 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Pfam PF08278 DNA primase DnaG DnaB-binding 487 614 1.8E-29 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 PIRSF PIRSF002811 2 625 3.1E-142 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 SUPERFAMILY SSF56731 118 433 1.57E-93 T 29-03-2018 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Gene3D G3DSA:3.90.580.10 1 103 3.1E-33 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 TIGRFAM TIGR01391 dnaG: DNA primase 5 424 1.3E-112 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Gene3D G3DSA:3.90.980.10 111 244 5.6E-39 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Pfam PF10410 DnaB-helicase binding domain of primase 377 431 2.3E-19 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 SMART SM00493 263 341 7.5E-14 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 SUPERFAMILY SSF57783 4 99 2.89E-32 T 29-03-2018 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Gene3D G3DSA:3.40.1360.10 245 375 1.1E-26 T 29-03-2018 MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 1.6E-35 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 Gene3D G3DSA:1.10.860.10 470 619 6.5E-40 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MSG_RS16625 50bfabf5da53c2a62ee8b31779df343c 639 SMART SM00400 37 91 2.2E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 Gene3D G3DSA:3.40.50.980 31 200 2.0E-25 T 29-03-2018 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 Gene3D G3DSA:3.30.300.30 498 610 5.5E-14 T 29-03-2018 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 SUPERFAMILY SSF56801 32 612 1.13E-81 T 29-03-2018 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 Gene3D G3DSA:2.30.38.10 385 495 1.5E-20 T 29-03-2018 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 Gene3D G3DSA:3.40.50.980 201 369 2.6E-20 T 29-03-2018 MSG_RS13425 c7c8816340b481d2945d28864e19bc56 618 Pfam PF00501 AMP-binding enzyme 41 502 1.0E-62 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02035 d42f8df3e559edb9bd93812b941ee942 196 Gene3D G3DSA:1.10.357.10 39 176 8.8E-16 T 29-03-2018 MSG_RS02035 d42f8df3e559edb9bd93812b941ee942 196 SUPERFAMILY SSF48498 68 176 1.33E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS02035 d42f8df3e559edb9bd93812b941ee942 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02035 d42f8df3e559edb9bd93812b941ee942 196 SUPERFAMILY SSF46689 2 63 3.39E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02035 d42f8df3e559edb9bd93812b941ee942 196 Gene3D G3DSA:1.10.10.60 1 38 8.9E-10 T 29-03-2018 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 Pfam PF00733 Asparagine synthase 258 627 2.3E-107 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 SUPERFAMILY SSF52402 249 397 4.19E-84 T 29-03-2018 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 SUPERFAMILY SSF52402 484 623 4.19E-84 T 29-03-2018 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 Gene3D G3DSA:3.60.20.10 1 236 1.5E-44 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 Gene3D G3DSA:3.40.50.620 237 633 1.5E-80 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 SUPERFAMILY SSF56235 2 231 1.37E-51 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 564 2.2E-135 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 PIRSF PIRSF001589 1 643 4.0E-163 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MSG_RS15340 fbf69e140f5b0833868c85f3fc7132de 648 Pfam PF13537 Glutamine amidotransferase domain 56 178 2.6E-36 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MSG_RS20980 d7bfba8fe884c158d00fb07c9e657d92 147 Gene3D G3DSA:3.30.530.20 6 144 2.4E-22 T 29-03-2018 IPR023393 START-like domain MSG_RS20980 d7bfba8fe884c158d00fb07c9e657d92 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 140 2.5E-15 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS20980 d7bfba8fe884c158d00fb07c9e657d92 147 SUPERFAMILY SSF55961 1 143 1.32E-26 T 29-03-2018 MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 194 3.0E-5 T 29-03-2018 MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.7E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.7E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.7E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.0E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 SUPERFAMILY SSF51735 10 250 9.94E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 Gene3D G3DSA:3.40.50.720 4 50 1.3E-9 T 29-03-2018 MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 Gene3D G3DSA:3.40.50.720 51 250 2.9E-65 T 29-03-2018 MSG_RS18005 834d43ffb1706f1e0f32e8778ef61cb3 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 8.3E-68 T 29-03-2018 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 Gene3D G3DSA:3.40.1390.30 1 125 7.5E-30 T 29-03-2018 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 353 7.7E-40 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 Gene3D G3DSA:3.30.70.120 131 222 3.6E-37 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 SUPERFAMILY SSF102705 4 369 3.01E-104 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 Gene3D G3DSA:3.40.1390.30 223 363 8.5E-11 T 29-03-2018 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 353 1.2E-60 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MSG_RS15560 c43ae565e7f7ef68bbd58473c8aac4a6 376 PIRSF PIRSF037489 1 371 1.8E-136 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria MSG_RS03420 9a93cb4dbd517bbe728efe34ad62c81a 343 Pfam PF11209 Protein of unknown function (DUF2993) 124 320 8.0E-18 T 29-03-2018 IPR021373 Protein of unknown function DUF2993 MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 Gene3D G3DSA:3.40.47.10 5 266 7.1E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 374 4.9E-34 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 SMART SM00825 Beta-ketoacyl synthase 13 408 2.9E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 254 1.2E-48 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 SUPERFAMILY SSF53901 221 417 6.57E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 SUPERFAMILY SSF53901 12 259 8.65E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15740 a17d05bfd19ad02b1a98c8a7656a7f1e 417 Gene3D G3DSA:3.40.47.10 270 417 1.5E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05680 cfeaeae39297b20459c75a178ac796de 140 Gene3D G3DSA:3.90.1010.10 1 138 1.1E-40 T 29-03-2018 MSG_RS05680 cfeaeae39297b20459c75a178ac796de 140 Pfam PF02657 Fe-S metabolism associated domain 12 133 3.2E-29 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MSG_RS05680 cfeaeae39297b20459c75a178ac796de 140 SUPERFAMILY SSF82649 2 135 8.89E-29 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 1.4E-5 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 52 66 1.4E-5 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 11 25 1.4E-5 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 8 520 52.865 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 SUPERFAMILY SSF52317 10 198 6.36E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 2.0E-8 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 55 64 2.0E-8 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.0E-8 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Pfam PF02540 NAD synthase 210 251 1.2E-5 T 29-03-2018 IPR022310 NAD/GMP synthase MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Gene3D G3DSA:3.30.300.10 395 520 1.7E-51 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 SUPERFAMILY SSF54810 399 520 2.09E-46 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 SUPERFAMILY SSF52402 185 440 9.7E-53 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Pfam PF00958 GMP synthase C terminal domain 427 519 3.2E-39 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Gene3D G3DSA:3.40.50.880 7 212 1.7E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Pfam PF00117 Glutamine amidotransferase class-I 13 191 5.5E-39 T 29-03-2018 IPR017926 Glutamine amidotransferase MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 11 195 2.3E-72 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00097 Anthranilate synthase component II signature 169 182 2.1E-6 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00097 Anthranilate synthase component II signature 82 93 2.1E-6 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 PRINTS PR00097 Anthranilate synthase component II signature 55 64 2.1E-6 T 29-03-2018 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 520 4.4E-145 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MSG_RS05170 e406232973c0116a8354a1ca255321e9 520 Gene3D G3DSA:3.40.50.620 213 394 1.4E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 SUPERFAMILY SSF47807 195 310 2.54E-20 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 185 1.0E-47 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 194 277 4.2E-19 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 SMART SM00279 192 227 8.6E-10 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 SMART SM00475 3 284 4.2E-101 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 SUPERFAMILY SSF88723 4 164 6.17E-37 T 29-03-2018 IPR029060 PIN domain-like MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 Gene3D G3DSA:1.10.150.20 204 285 2.0E-19 T 29-03-2018 MSG_RS14705 fac6f68cd98141f7a22265dfa3498520 318 Gene3D G3DSA:3.40.50.1010 3 203 2.2E-54 T 29-03-2018 IPR029060 PIN domain-like MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 SUPERFAMILY SSF50129 1 176 3.62E-54 T 29-03-2018 IPR011032 GroES-like MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.9E-13 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 SUPERFAMILY SSF51735 157 353 2.22E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 6.1E-24 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 Pfam PF00107 Zinc-binding dehydrogenase 189 258 3.7E-12 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 Gene3D G3DSA:3.40.50.720 179 347 4.9E-29 T 29-03-2018 MSG_RS06480 8a9b814414e20c14ece1a5d69c31c970 400 Gene3D G3DSA:3.90.180.10 1 178 1.3E-38 T 29-03-2018 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 1.7E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 Gene3D G3DSA:1.10.357.10 88 200 5.7E-8 T 29-03-2018 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 Gene3D G3DSA:1.10.260.40 43 87 5.3E-12 T 29-03-2018 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 SUPERFAMILY SSF48498 89 197 2.25E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 Gene3D G3DSA:1.10.10.60 1 42 2.0E-14 T 29-03-2018 MSG_RS00925 10d34c008acd594b847de1d3f0901e46 205 SUPERFAMILY SSF46689 8 92 2.44E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19485 799fe3856a507ae3ff51200ea469f24c 134 Gene3D G3DSA:3.10.180.10 2 130 3.3E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS19485 799fe3856a507ae3ff51200ea469f24c 134 SUPERFAMILY SSF54593 2 121 2.61E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS19485 799fe3856a507ae3ff51200ea469f24c 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 1.5E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 Gene3D G3DSA:3.40.50.1820 421 704 4.0E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 SUPERFAMILY SSF53474 438 684 3.72E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 11 429 1.4E-117 T 29-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 Pfam PF00326 Prolyl oligopeptidase family 485 702 1.6E-61 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 SUPERFAMILY SSF50993 8 435 6.8E-94 T 29-03-2018 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 Gene3D G3DSA:2.130.10.120 79 420 8.4E-65 T 29-03-2018 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 531 561 - T 29-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 554 574 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 520 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 470 488 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 613 628 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 631 653 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS21940 a35575210ac2b66a0abf3e1bfad7690f 711 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 524 543 2.1E-56 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 40 126 1.7E-19 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 SUPERFAMILY SSF81296 35 185 5.88E-40 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 SUPERFAMILY SSF51011 629 738 2.95E-24 T 29-03-2018 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 36 738 2.2E-297 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Gene3D G3DSA:2.60.40.10 36 175 2.1E-49 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Gene3D G3DSA:3.20.20.80 176 619 5.9E-113 T 29-03-2018 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 SMART SM00642 208 607 1.8E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Pfam PF00128 Alpha amylase, catalytic domain 227 315 1.1E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Pfam PF00128 Alpha amylase, catalytic domain 349 570 2.0E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 SUPERFAMILY SSF51445 172 510 1.55E-132 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 SUPERFAMILY SSF51445 539 615 1.55E-132 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS11045 06cf3eaa35aa963a329cf5e5ef5d2e23 741 Gene3D G3DSA:2.60.40.1180 620 741 5.1E-32 T 29-03-2018 MSG_RS19765 49fe46b0967f9e18d0f48001a49a04b7 380 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 293 376 1.0E-19 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS19765 49fe46b0967f9e18d0f48001a49a04b7 380 Pfam PF00823 PPE family 7 160 1.1E-19 T 29-03-2018 IPR000030 PPE family MSG_RS19765 49fe46b0967f9e18d0f48001a49a04b7 380 SUPERFAMILY SSF140459 3 166 4.97E-21 T 29-03-2018 MSG_RS24240 28509127ac741df6240bbbfb528aa968 255 SUPERFAMILY SSF69593 14 205 3.27E-34 T 29-03-2018 MSG_RS24240 28509127ac741df6240bbbfb528aa968 255 Gene3D G3DSA:3.40.1130.10 2 213 3.4E-44 T 29-03-2018 MSG_RS24240 28509127ac741df6240bbbfb528aa968 255 SMART SM00563 37 153 3.1E-33 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS24240 28509127ac741df6240bbbfb528aa968 255 Pfam PF01553 Acyltransferase 22 150 6.3E-32 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 SUPERFAMILY SSF100879 243 342 2.98E-23 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Gene3D G3DSA:3.30.1490.100 247 356 3.5E-24 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Hamap MF_01113 DNA polymerase IV [dinB]. 3 357 33.022 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Gene3D G3DSA:3.30.70.270 42 110 3.5E-12 T 29-03-2018 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Gene3D G3DSA:3.30.70.270 118 173 1.6E-12 T 29-03-2018 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Pfam PF00817 impB/mucB/samB family 9 156 1.5E-33 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 SUPERFAMILY SSF56672 3 241 2.94E-67 T 29-03-2018 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Pfam PF11798 IMS family HHH motif 170 200 4.7E-7 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 349 1.9E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS10945 7f5c2977e256eb0e210af09cfaf7caef 472 Gene3D G3DSA:1.10.150.20 174 246 4.4E-22 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 Gene3D G3DSA:1.20.58.100 412 518 3.7E-20 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 Pfam PF00890 FAD binding domain 11 386 4.6E-90 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 SUPERFAMILY SSF56425 228 346 5.23E-32 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.8E-6 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 364 371 1.8E-6 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 498 3.6E-191 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 SUPERFAMILY SSF46977 421 516 1.7E-20 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 Pfam PF02910 Fumarate reductase flavoprotein C-term 472 500 1.1E-5 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 Gene3D G3DSA:3.50.50.60 300 402 3.1E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 Gene3D G3DSA:3.50.50.60 1 299 1.7E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 2.8E-8 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.8E-8 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.8E-8 T 29-03-2018 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 SUPERFAMILY SSF51905 4 245 1.58E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11135 e5bee5820dc18e2b24fea2330655e46e 528 SUPERFAMILY SSF51905 350 404 1.58E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 Pfam PF02734 DAK2 domain 38 214 3.5E-26 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 SMART SM01121 242 558 6.4E-86 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 Pfam PF13684 Dihydroxyacetone kinase family 243 558 9.0E-68 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 SUPERFAMILY SSF101473 8 216 4.32E-28 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 SMART SM01120 38 215 9.3E-36 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MSG_RS07890 5a39aa7cab7cd7ac0b3b4e30d04e3238 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 13 558 1.2E-138 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV MSG_RS24045 4ef82e7b487b17bfebb4d0b3914896f7 305 SUPERFAMILY SSF53448 4 276 3.86E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS24045 4ef82e7b487b17bfebb4d0b3914896f7 305 Gene3D G3DSA:3.90.550.10 2 277 3.0E-17 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS24045 4ef82e7b487b17bfebb4d0b3914896f7 305 Pfam PF00535 Glycosyl transferase family 2 7 116 3.7E-10 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS07475 ed81de2d440e2b4bc5943d2b7b08b931 225 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 216 2.6E-42 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS07475 ed81de2d440e2b4bc5943d2b7b08b931 225 Gene3D G3DSA:3.90.226.10 5 224 3.3E-52 T 29-03-2018 MSG_RS07475 ed81de2d440e2b4bc5943d2b7b08b931 225 SUPERFAMILY SSF52096 15 219 4.65E-54 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS16735 9656cf6372e7a56822a044ce1bacc560 113 PIRSF PIRSF006909 1 103 7.3E-58 T 29-03-2018 IPR014447 Uncharacterised conserved protein UCP006909 MSG_RS05700 6f094197cbbaa897722efb7d0cd0bb5e 546 Gene3D G3DSA:3.90.226.10 10 277 5.0E-79 T 29-03-2018 MSG_RS05700 6f094197cbbaa897722efb7d0cd0bb5e 546 Pfam PF01039 Carboxyl transferase domain 47 544 6.8E-200 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS05700 6f094197cbbaa897722efb7d0cd0bb5e 546 Gene3D G3DSA:3.90.226.10 279 537 1.1E-72 T 29-03-2018 MSG_RS05700 6f094197cbbaa897722efb7d0cd0bb5e 546 SUPERFAMILY SSF52096 291 546 3.04E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS05700 6f094197cbbaa897722efb7d0cd0bb5e 546 SUPERFAMILY SSF52096 20 270 1.61E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 7 271 4.1E-92 T 29-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 Pfam PF13622 Thioesterase-like superfamily 32 269 1.6E-52 T 29-03-2018 MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 SUPERFAMILY SSF54637 2 112 4.03E-30 T 29-03-2018 IPR029069 HotDog domain MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 SUPERFAMILY SSF54637 115 271 3.73E-45 T 29-03-2018 IPR029069 HotDog domain MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 Gene3D G3DSA:3.10.129.10 134 274 1.3E-44 T 29-03-2018 MSG_RS09620 b5f59992251ccfbacb011fc27bbdd645 278 Gene3D G3DSA:3.10.129.10 1 114 1.2E-34 T 29-03-2018 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Pfam PF03129 Anticodon binding domain 492 569 2.7E-12 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS08505 db22a5c121824b036b020673af374af7 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 470 1.1E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Gene3D G3DSA:3.90.960.10 257 399 2.8E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Gene3D G3DSA:3.40.50.800 471 581 8.3E-25 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS08505 db22a5c121824b036b020673af374af7 582 SUPERFAMILY SSF55826 281 391 1.1E-9 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Pfam PF04073 Aminoacyl-tRNA editing domain 261 391 6.3E-20 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MSG_RS08505 db22a5c121824b036b020673af374af7 582 SUPERFAMILY SSF52954 476 572 1.31E-22 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS08505 db22a5c121824b036b020673af374af7 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 566 1.6E-160 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MSG_RS08505 db22a5c121824b036b020673af374af7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 3.1E-14 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MSG_RS08505 db22a5c121824b036b020673af374af7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 3.1E-14 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MSG_RS08505 db22a5c121824b036b020673af374af7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 3.1E-14 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MSG_RS08505 db22a5c121824b036b020673af374af7 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 3.1E-14 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Gene3D G3DSA:3.30.930.10 26 256 8.3E-53 T 29-03-2018 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Gene3D G3DSA:3.30.930.10 400 470 9.2E-8 T 29-03-2018 MSG_RS08505 db22a5c121824b036b020673af374af7 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 580 35.588 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MSG_RS08505 db22a5c121824b036b020673af374af7 582 SUPERFAMILY SSF55681 419 489 3.56E-83 T 29-03-2018 MSG_RS08505 db22a5c121824b036b020673af374af7 582 SUPERFAMILY SSF55681 12 239 3.56E-83 T 29-03-2018 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 SUPERFAMILY SSF48179 169 290 3.06E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 290 26.697 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 PIRSF PIRSF000193 5 293 2.5E-59 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 246 268 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 Gene3D G3DSA:3.40.50.720 5 170 2.6E-27 T 29-03-2018 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 290 5.6E-40 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 290 9.1E-85 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 SUPERFAMILY SSF51735 7 167 3.41E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 106 5.0E-21 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MSG_RS03520 aa3321dc64ae600a374406d44f846f95 295 Gene3D G3DSA:1.10.3730.10 171 294 1.0E-42 T 29-03-2018 MSG_RS23735 88d0a079ea493fa4c2891cde845224ca 323 SUPERFAMILY SSF51679 10 322 3.66E-49 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS23735 88d0a079ea493fa4c2891cde845224ca 323 Pfam PF00296 Luciferase-like monooxygenase 14 241 4.3E-29 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS23735 88d0a079ea493fa4c2891cde845224ca 323 Gene3D G3DSA:3.20.20.30 3 323 2.8E-47 T 29-03-2018 MSG_RS00185 ac6081422565ba78addd7400d2838cac 262 SMART SM00530 9 64 1.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS00185 ac6081422565ba78addd7400d2838cac 262 Gene3D G3DSA:1.10.260.40 2 228 1.4E-12 T 29-03-2018 MSG_RS00185 ac6081422565ba78addd7400d2838cac 262 Pfam PF01381 Helix-turn-helix 10 61 2.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS00185 ac6081422565ba78addd7400d2838cac 262 SUPERFAMILY SSF47413 6 62 1.29E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS19675 ec97554bc5a0fbe3d263e3935027ce60 260 Gene3D G3DSA:1.10.12.10 221 258 4.6E-23 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS19675 ec97554bc5a0fbe3d263e3935027ce60 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS19675 ec97554bc5a0fbe3d263e3935027ce60 260 Gene3D G3DSA:3.90.226.10 5 220 9.3E-74 T 29-03-2018 MSG_RS19675 ec97554bc5a0fbe3d263e3935027ce60 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 4.9E-82 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS19675 ec97554bc5a0fbe3d263e3935027ce60 260 SUPERFAMILY SSF52096 4 259 1.76E-90 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 Gene3D G3DSA:3.30.465.10 89 233 3.5E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 442 2.0E-55 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 SUPERFAMILY SSF55103 216 446 9.97E-42 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 Pfam PF01565 FAD binding domain 38 173 3.9E-33 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 SUPERFAMILY SSF56176 3 213 1.01E-60 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 Gene3D G3DSA:3.30.43.10 2 88 1.4E-21 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS01580 cf29aeedfca603fd47143db7ca0e77ec 447 Gene3D G3DSA:1.10.45.10 406 445 9.0E-10 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 Pfam PF00270 DEAD/DEAH box helicase 22 167 8.3E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 Gene3D G3DSA:3.40.50.300 4 190 1.5E-34 T 29-03-2018 MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SMART SM00487 14 196 1.6E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 Gene3D G3DSA:3.40.50.300 221 557 1.4E-18 T 29-03-2018 MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 Pfam PF00271 Helicase conserved C-terminal domain 345 421 4.7E-5 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SMART SM00490 336 421 6.0E-15 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 Pfam PF08148 DSHCT (NUC185) domain 740 912 3.0E-38 T 29-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SMART SM01142 736 917 1.9E-63 T 29-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SUPERFAMILY SSF52540 250 299 6.69E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SUPERFAMILY SSF52540 27 169 6.69E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14715 7cbacfa48d80931c0b026eeb861d3465 917 SUPERFAMILY SSF52540 341 435 6.69E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00420 eb4247aa8dba23ce0f71835f7215e20f 113 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 19 104 4.1E-19 T 29-03-2018 IPR009241 Toxin HigB-like MSG_RS00420 eb4247aa8dba23ce0f71835f7215e20f 113 Gene3D G3DSA:3.30.2310.20 8 94 1.4E-5 T 29-03-2018 MSG_RS01285 c10ceccb78878b862b108f8bc3ad406c 151 Pfam PF01575 MaoC like domain 12 131 4.7E-32 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS01285 c10ceccb78878b862b108f8bc3ad406c 151 SUPERFAMILY SSF54637 3 148 1.88E-40 T 29-03-2018 IPR029069 HotDog domain MSG_RS01285 c10ceccb78878b862b108f8bc3ad406c 151 Gene3D G3DSA:3.10.129.10 1 151 5.6E-39 T 29-03-2018 MSG_RS02950 3bd2fe811b2a67409a1582e6643f9198 445 Gene3D G3DSA:3.20.20.30 1 445 3.4E-96 T 29-03-2018 MSG_RS02950 3bd2fe811b2a67409a1582e6643f9198 445 PIRSF PIRSF000337 2 445 2.1E-143 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS02950 3bd2fe811b2a67409a1582e6643f9198 445 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 14 434 8.6E-130 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS02950 3bd2fe811b2a67409a1582e6643f9198 445 Pfam PF00296 Luciferase-like monooxygenase 22 389 6.7E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02950 3bd2fe811b2a67409a1582e6643f9198 445 SUPERFAMILY SSF51679 3 439 4.19E-114 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 72 140 3.7E-32 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 SMART SM00529 33 132 2.7E-46 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 42 7.0E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 61 7.0E-5 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Pfam PF04023 FeoA domain 152 230 1.3E-21 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Gene3D G3DSA:1.10.60.10 88 132 1.9E-24 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 10 69 2.9E-20 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 SUPERFAMILY SSF47979 72 146 1.31E-27 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Gene3D G3DSA:1.10.10.10 3 87 9.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 SUPERFAMILY SSF46785 9 99 7.34E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 SUPERFAMILY SSF50037 156 229 7.78E-7 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 Gene3D G3DSA:2.30.30.90 133 230 1.6E-25 T 29-03-2018 MSG_RS08615 5afd159b7037794b6af1c1cf67afa64c 230 SMART SM00899 152 230 1.3E-11 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 Gene3D G3DSA:3.30.420.40 91 271 3.2E-53 T 29-03-2018 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 SUPERFAMILY SSF53067 125 259 1.38E-30 T 29-03-2018 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 SUPERFAMILY SSF53067 2 124 2.2E-22 T 29-03-2018 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 30.22 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 256 2.2E-85 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS22815 7a91bcd31d45225abe2a2a10eefbb7c3 271 Pfam PF03309 Type III pantothenate kinase 2 208 1.1E-53 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS14960 10056e03ef71b6259e503184f1aa8402 176 Gene3D G3DSA:3.90.280.10 1 176 2.2E-51 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS14960 10056e03ef71b6259e503184f1aa8402 176 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 173 9.7E-35 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS14960 10056e03ef71b6259e503184f1aa8402 176 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 173 1.2E-39 T 29-03-2018 IPR005247 YbhB/YbcL MSG_RS14960 10056e03ef71b6259e503184f1aa8402 176 SUPERFAMILY SSF49777 2 167 2.88E-49 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 SMART SM00382 285 441 6.7E-22 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 Gene3D G3DSA:1.20.120.330 20 152 2.6E-6 T 29-03-2018 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 Gene3D G3DSA:3.40.50.300 227 455 5.8E-55 T 29-03-2018 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 ProSitePatterns PS00674 AAA-protein family signature. 409 427 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 587 4.3E-263 T 29-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 SUPERFAMILY SSF52540 514 539 7.94E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 SUPERFAMILY SSF52540 247 473 7.94E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 588 50.396 T 29-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 289 439 4.3E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS14775 7903b24e41482ac322ce1d7de1a50ee1 609 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 246 9.3E-55 T 29-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Pfam PF00989 PAS fold 25 136 5.2E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Gene3D G3DSA:3.30.450.20 26 141 7.6E-16 T 29-03-2018 MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SMART SM00387 382 470 7.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Gene3D G3DSA:3.30.450.20 142 363 3.6E-25 T 29-03-2018 MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Pfam PF07730 Histidine kinase 281 342 8.5E-6 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Gene3D G3DSA:3.30.565.10 364 470 5.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SUPERFAMILY SSF55785 25 135 1.34E-16 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SMART SM00091 146 212 4.3E-10 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SMART SM00091 25 93 0.13 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 469 4.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 266 1.8E-24 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 37 145 8.9E-14 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 Pfam PF13426 PAS domain 156 261 1.8E-15 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SMART SM00086 222 262 1.4 T 29-03-2018 IPR001610 PAC motif MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SMART SM00086 98 140 34.0 T 29-03-2018 IPR001610 PAC motif MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SUPERFAMILY SSF55785 157 269 1.95E-26 T 29-03-2018 IPR000014 PAS domain MSG_RS13945 06d35266bdc0e2aa5c9e7938825b352d 470 SUPERFAMILY SSF55874 352 469 2.1E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 Gene3D G3DSA:1.10.260.40 45 74 2.2E-6 T 29-03-2018 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 9.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 Gene3D G3DSA:1.10.10.60 8 44 5.4E-10 T 29-03-2018 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 SUPERFAMILY SSF46689 10 93 1.8E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 SUPERFAMILY SSF48498 90 183 9.53E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17555 a391837206a2574e2a52f1fcb4c41e43 197 Gene3D G3DSA:1.10.357.10 75 192 2.1E-18 T 29-03-2018 MSG_RS08350 3d8308d1a8b82402cdb61a11637c4848 79 Gene3D G3DSA:1.10.1470.10 9 78 2.2E-13 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS08350 3d8308d1a8b82402cdb61a11637c4848 79 SUPERFAMILY SSF69047 11 63 1.09E-7 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS08350 3d8308d1a8b82402cdb61a11637c4848 79 Pfam PF05532 CsbD-like 12 61 8.8E-11 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS12675 9212db23cd0e1e77fe7e0b61c8b3bf2f 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.7E-19 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS12675 9212db23cd0e1e77fe7e0b61c8b3bf2f 98 Gene3D G3DSA:1.10.287.1060 1 98 7.0E-14 T 29-03-2018 MSG_RS12675 9212db23cd0e1e77fe7e0b61c8b3bf2f 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 1.2E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS12675 9212db23cd0e1e77fe7e0b61c8b3bf2f 98 SUPERFAMILY SSF140453 4 97 3.79E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS10150 d19ac19cf69085b14089ce04ab018150 288 Gene3D G3DSA:3.20.20.60 2 288 5.4E-87 T 29-03-2018 MSG_RS10150 d19ac19cf69085b14089ce04ab018150 288 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 251 4.4E-62 T 29-03-2018 MSG_RS10150 d19ac19cf69085b14089ce04ab018150 288 ProSitePatterns PS00161 Isocitrate lyase signature. 117 122 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS10150 d19ac19cf69085b14089ce04ab018150 288 SUPERFAMILY SSF51621 5 287 2.83E-90 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS15670 e00ab6182bf17bbd075bc99999e54696 660 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 378 622 1.9E-79 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MSG_RS17120 52e3964209e9793e9f791f73b7eef20f 282 Gene3D G3DSA:3.40.50.1220 3 280 5.5E-62 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS17120 52e3964209e9793e9f791f73b7eef20f 282 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 2 272 63.04 T 29-03-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 MSG_RS17120 52e3964209e9793e9f791f73b7eef20f 282 Pfam PF02146 Sir2 family 25 227 3.1E-40 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 MSG_RS17120 52e3964209e9793e9f791f73b7eef20f 282 SUPERFAMILY SSF52467 165 276 1.03E-72 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS17120 52e3964209e9793e9f791f73b7eef20f 282 SUPERFAMILY SSF52467 14 136 1.03E-72 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 8.5E-169 T 29-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 363 38.468 T 29-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 Pfam PF00472 RF-1 domain 228 335 8.2E-36 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 Gene3D G3DSA:1.20.58.410 3 114 2.1E-28 T 29-03-2018 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 Gene3D G3DSA:3.30.160.20 223 311 7.0E-31 T 29-03-2018 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 Pfam PF03462 PCRF domain 29 218 1.1E-56 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 SMART SM00937 83 193 2.2E-47 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MSG_RS06865 1c41ae4ec7a1dcf423fcc2e0b85ed65c 368 SUPERFAMILY SSF75620 28 364 1.27E-119 T 29-03-2018 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 SMART SM00304 241 293 1.1E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 SUPERFAMILY SSF158472 243 290 1.57E-9 T 29-03-2018 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 SMART SM00044 290 482 1.9E-15 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 322 493 6.7E-29 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 SUPERFAMILY SSF55073 318 498 3.77E-50 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 Gene3D G3DSA:3.30.70.1230 314 517 4.5E-43 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS05065 10f1f99e51acb859385e525ef7caf1c7 530 Pfam PF00672 HAMP domain 243 289 4.3E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 ProSitePatterns PS00789 Chorismate synthase signature 3. 341 357 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 5.4E-125 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 Pfam PF01264 Chorismate synthase 2 367 1.9E-117 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 PIRSF PIRSF001456 1 389 1.7E-126 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 Hamap MF_00300 Chorismate synthase [aroC]. 2 374 34.203 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 SUPERFAMILY SSF103263 2 389 1.83E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS09910 bc4bc2b633c2aba2f8197caff4cc559b 402 Gene3D G3DSA:3.60.150.10 1 402 8.9E-145 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MSG_RS14475 ab18340d0fb4a5fc636cae4ac624cec1 266 Gene3D G3DSA:3.10.450.50 5 144 3.7E-15 T 29-03-2018 MSG_RS14475 ab18340d0fb4a5fc636cae4ac624cec1 266 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 12 128 4.8E-8 T 29-03-2018 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 MSG_RS14475 ab18340d0fb4a5fc636cae4ac624cec1 266 Gene3D G3DSA:3.10.450.50 170 262 0.018 T 29-03-2018 MSG_RS14475 ab18340d0fb4a5fc636cae4ac624cec1 266 SUPERFAMILY SSF54427 5 131 9.4E-17 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS02135 da1d5adde4e9a2dd9ce96e7f90848e80 1411 Gene3D G3DSA:2.60.120.260 951 1130 2.6E-7 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS02135 da1d5adde4e9a2dd9ce96e7f90848e80 1411 Pfam PF11847 Domain of unknown function (DUF3367) 13 701 7.3E-280 T 29-03-2018 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 MSG_RS02135 da1d5adde4e9a2dd9ce96e7f90848e80 1411 SUPERFAMILY SSF49785 720 838 3.09E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS02135 da1d5adde4e9a2dd9ce96e7f90848e80 1411 Gene3D G3DSA:2.60.120.260 717 855 8.9E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS02135 da1d5adde4e9a2dd9ce96e7f90848e80 1411 SUPERFAMILY SSF49785 964 1062 1.39E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS14340 38af9e76e9c2badb407f963d75aaaaeb 355 SUPERFAMILY SSF56645 19 213 2.23E-24 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS14340 38af9e76e9c2badb407f963d75aaaaeb 355 Gene3D G3DSA:2.40.110.10 122 214 2.3E-12 T 29-03-2018 MSG_RS14340 38af9e76e9c2badb407f963d75aaaaeb 355 Gene3D G3DSA:1.20.140.10 231 348 4.6E-4 T 29-03-2018 MSG_RS14340 38af9e76e9c2badb407f963d75aaaaeb 355 Gene3D G3DSA:1.10.540.10 12 112 1.1E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06060 ffefb2b37c630ca2c50e7c8d0408565e 328 Pfam PF03193 RsgA GTPase 97 265 6.8E-41 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MSG_RS06060 ffefb2b37c630ca2c50e7c8d0408565e 328 SUPERFAMILY SSF52540 113 287 4.18E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06060 ffefb2b37c630ca2c50e7c8d0408565e 328 Gene3D G3DSA:3.40.50.300 109 265 4.3E-18 T 29-03-2018 MSG_RS06060 ffefb2b37c630ca2c50e7c8d0408565e 328 Gene3D G3DSA:1.10.40.50 266 328 1.7E-12 T 29-03-2018 MSG_RS06060 ffefb2b37c630ca2c50e7c8d0408565e 328 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 304 2.3E-40 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MSG_RS09595 635541d868353262f1b87b0237cf9f7d 374 Pfam PF13439 Glycosyltransferase Family 4 14 172 1.2E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS09595 635541d868353262f1b87b0237cf9f7d 374 SUPERFAMILY SSF53756 2 364 1.86E-76 T 29-03-2018 MSG_RS09595 635541d868353262f1b87b0237cf9f7d 374 Pfam PF13692 Glycosyl transferases group 1 189 329 3.4E-33 T 29-03-2018 MSG_RS09595 635541d868353262f1b87b0237cf9f7d 374 Gene3D G3DSA:3.40.50.2000 179 347 3.3E-42 T 29-03-2018 MSG_RS09595 635541d868353262f1b87b0237cf9f7d 374 Gene3D G3DSA:3.40.50.2000 1 178 9.9E-12 T 29-03-2018 MSG_RS06055 899066653bae43f5573f7c5dfb9b4862 157 Gene3D G3DSA:1.10.10.10 11 155 8.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06055 899066653bae43f5573f7c5dfb9b4862 157 Pfam PF01638 HxlR-like helix-turn-helix 28 116 2.5E-14 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS06055 899066653bae43f5573f7c5dfb9b4862 157 SUPERFAMILY SSF46785 19 140 5.07E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13795 915e0149df17fafffcdce5883da96caf 221 SUPERFAMILY SSF55469 102 215 5.23E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13795 915e0149df17fafffcdce5883da96caf 221 SUPERFAMILY SSF55469 1 63 5.23E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13795 915e0149df17fafffcdce5883da96caf 221 Pfam PF00881 Nitroreductase family 8 192 7.9E-28 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS13795 915e0149df17fafffcdce5883da96caf 221 Gene3D G3DSA:3.40.109.10 1 212 4.1E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 PRINTS PR00332 Histidine triad family signature 4 20 7.3E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 PRINTS PR00332 Histidine triad family signature 87 97 7.3E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 PRINTS PR00332 Histidine triad family signature 25 43 7.3E-14 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 ProSitePatterns PS00892 HIT domain signature. 80 98 - T 29-03-2018 IPR019808 Histidine triad, conserved site MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 Gene3D G3DSA:3.30.428.10 3 134 1.3E-25 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 SUPERFAMILY SSF54197 3 132 2.17E-30 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS22055 53fe4be9593293c2042c76954d76ef99 134 Pfam PF01230 HIT domain 11 101 7.1E-21 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS06590 58d6a1b34a744f5dd711f3f419893ef8 369 SUPERFAMILY SSF53756 16 353 2.39E-48 T 29-03-2018 MSG_RS06590 58d6a1b34a744f5dd711f3f419893ef8 369 Gene3D G3DSA:3.40.50.2000 16 165 5.2E-12 T 29-03-2018 MSG_RS06590 58d6a1b34a744f5dd711f3f419893ef8 369 Gene3D G3DSA:3.40.50.2000 167 338 3.0E-28 T 29-03-2018 MSG_RS06590 58d6a1b34a744f5dd711f3f419893ef8 369 Pfam PF00534 Glycosyl transferases group 1 183 331 1.0E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS06590 58d6a1b34a744f5dd711f3f419893ef8 369 Pfam PF13579 Glycosyl transferase 4-like domain 16 169 4.5E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS04915 75637b25534f9b397903071766273076 143 Pfam PF00380 Ribosomal protein S9/S16 23 143 3.6E-43 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MSG_RS04915 75637b25534f9b397903071766273076 143 SUPERFAMILY SSF54211 19 143 6.45E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS04915 75637b25534f9b397903071766273076 143 Gene3D G3DSA:3.30.230.10 16 143 2.3E-48 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS04915 75637b25534f9b397903071766273076 143 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 14 143 32.538 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MSG_RS04915 75637b25534f9b397903071766273076 143 ProSitePatterns PS00360 Ribosomal protein S9 signature. 82 100 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 3.4E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 366 2.7E-11 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 SUPERFAMILY SSF56645 4 234 1.57E-57 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Gene3D G3DSA:1.20.140.10 212 371 2.2E-28 T 29-03-2018 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Gene3D G3DSA:2.40.110.10 113 211 9.3E-33 T 29-03-2018 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Gene3D G3DSA:1.10.540.10 2 112 1.3E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 SUPERFAMILY SSF47203 223 367 4.19E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21330 6dd4011b0d71c6b6b63899876e550107 371 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 211 3.4E-22 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS01460 4dfb59e0de2b819efea7131c80e1cfe1 168 Pfam PF12680 SnoaL-like domain 23 75 8.8E-9 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS01460 4dfb59e0de2b819efea7131c80e1cfe1 168 Gene3D G3DSA:3.10.450.50 2 163 6.2E-20 T 29-03-2018 MSG_RS01460 4dfb59e0de2b819efea7131c80e1cfe1 168 SUPERFAMILY SSF54427 4 137 1.45E-22 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS04650 bbfc08b983eb707c0c5b2f0c4f2dba29 343 Gene3D G3DSA:3.40.50.720 3 126 1.2E-14 T 29-03-2018 MSG_RS04650 bbfc08b983eb707c0c5b2f0c4f2dba29 343 SUPERFAMILY SSF51735 1 133 5.73E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 SUPERFAMILY SSF56645 6 240 1.31E-51 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Gene3D G3DSA:1.20.140.10 221 392 1.9E-19 T 29-03-2018 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 2.0E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 319 381 1.3E-5 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 119 3.5E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Gene3D G3DSA:2.40.110.10 124 220 4.2E-30 T 29-03-2018 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 Gene3D G3DSA:1.10.540.10 1 122 3.5E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17920 0eb35956554eb5d161a50eb2e29a1bd2 397 SUPERFAMILY SSF47203 230 384 5.15E-11 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17285 8526cedfed951536a89c9144c4bd2b06 223 SMART SM00507 126 175 1.4E-15 T 29-03-2018 IPR003615 HNH nuclease MSG_RS17285 8526cedfed951536a89c9144c4bd2b06 223 Pfam PF14279 HNH endonuclease 139 185 1.1E-13 T 29-03-2018 IPR029471 HNH endonuclease 5 MSG_RS17285 8526cedfed951536a89c9144c4bd2b06 223 Gene3D G3DSA:3.40.1800.10 119 190 8.9E-19 T 29-03-2018 MSG_RS05110 c0b891f8f19900f1ced592164ec67def 137 Pfam PF17252 Family of unknown function (DUF5319) 9 122 3.6E-50 T 29-03-2018 IPR035165 Protein of unknown function DUF5319 MSG_RS05110 c0b891f8f19900f1ced592164ec67def 137 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 25 120 3.0E-49 T 29-03-2018 IPR035165 Protein of unknown function DUF5319 MSG_RS06205 f01de6022bfdcb67fae0025111645b44 366 Gene3D G3DSA:3.60.120.10 13 365 9.1E-90 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS06205 f01de6022bfdcb67fae0025111645b44 366 Pfam PF00425 chorismate binding enzyme 91 354 5.4E-70 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MSG_RS06205 f01de6022bfdcb67fae0025111645b44 366 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 91 362 6.5E-76 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MSG_RS06205 f01de6022bfdcb67fae0025111645b44 366 SUPERFAMILY SSF56322 40 363 5.1E-83 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS23920 5df8b0e301f7b69ebf741c61333c7325 320 Pfam PF00107 Zinc-binding dehydrogenase 146 209 3.0E-8 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS23920 5df8b0e301f7b69ebf741c61333c7325 320 Gene3D G3DSA:3.40.50.720 147 265 1.1E-14 T 29-03-2018 MSG_RS23920 5df8b0e301f7b69ebf741c61333c7325 320 Gene3D G3DSA:3.90.180.10 1 146 2.0E-23 T 29-03-2018 MSG_RS23920 5df8b0e301f7b69ebf741c61333c7325 320 SUPERFAMILY SSF50129 1 137 6.06E-16 T 29-03-2018 IPR011032 GroES-like MSG_RS23920 5df8b0e301f7b69ebf741c61333c7325 320 SUPERFAMILY SSF51735 107 265 5.34E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12620 1140d8668e1fbf05eaf5a82e1bbef599 156 SUPERFAMILY SSF54427 2 143 2.06E-23 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS12620 1140d8668e1fbf05eaf5a82e1bbef599 156 Gene3D G3DSA:3.10.450.50 1 146 1.0E-23 T 29-03-2018 MSG_RS12620 1140d8668e1fbf05eaf5a82e1bbef599 156 Pfam PF13577 SnoaL-like domain 5 135 1.1E-18 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SMART SM00491 514 643 2.9E-43 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SMART SM00487 20 313 3.9E-6 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 Pfam PF13307 Helicase C-terminal domain 497 656 1.0E-25 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 414 428 5.32E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 478 626 5.32E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 202 273 5.32E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 38 92 5.32E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 212 256 2.05E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 SUPERFAMILY SSF52540 10 120 2.05E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 Gene3D G3DSA:3.40.50.300 24 441 7.7E-26 T 29-03-2018 MSG_RS18110 cdcc3dde7b67030cc520b05d527b513b 682 Gene3D G3DSA:3.40.50.300 486 675 1.3E-6 T 29-03-2018 MSG_RS20860 f1067da2578dc70ed78b4a9885e2d796 224 SUPERFAMILY SSF89562 18 191 2.75E-30 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS20860 f1067da2578dc70ed78b4a9885e2d796 224 Gene3D G3DSA:3.50.30.40 13 201 1.2E-38 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS20860 f1067da2578dc70ed78b4a9885e2d796 224 Pfam PF03737 Aldolase/RraA 20 181 7.8E-28 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS11660 b04e50515e034111bc540126a80fd03b 422 ProSitePatterns PS01219 Ammonium transporters signature. 161 186 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MSG_RS11660 b04e50515e034111bc540126a80fd03b 422 Pfam PF00909 Ammonium Transporter Family 10 405 5.3E-121 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MSG_RS11660 b04e50515e034111bc540126a80fd03b 422 Gene3D G3DSA:1.10.3430.10 1 386 2.7E-128 T 29-03-2018 MSG_RS11660 b04e50515e034111bc540126a80fd03b 422 TIGRFAM TIGR00836 amt: ammonium transporter 9 405 3.3E-134 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MSG_RS11660 b04e50515e034111bc540126a80fd03b 422 SUPERFAMILY SSF111352 5 386 2.22E-121 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 Pfam PF00854 POT family 96 465 1.4E-54 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 492 7.4E-110 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 SUPERFAMILY SSF103473 289 487 2.79E-23 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 SUPERFAMILY SSF103473 12 215 2.79E-23 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 157 169 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 Gene3D G3DSA:1.20.1250.20 285 494 1.2E-7 T 29-03-2018 MSG_RS06085 ae61b0ac3f4bb6c8ec51685301e49292 496 Gene3D G3DSA:1.20.1250.20 17 222 7.4E-21 T 29-03-2018 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 317 2.4E-12 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SUPERFAMILY SSF52540 548 838 4.61E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Gene3D G3DSA:1.10.1780.10 5 151 7.7E-33 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SUPERFAMILY SSF52540 157 547 4.45E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 840 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Gene3D G3DSA:3.40.50.300 554 729 1.6E-45 T 29-03-2018 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Gene3D G3DSA:1.10.8.60 344 549 3.9E-45 T 29-03-2018 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 749 5.6E-50 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SMART SM00382 198 344 4.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SMART SM00382 599 757 1.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SMART SM01086 756 847 5.2E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 SUPERFAMILY SSF81923 7 155 1.37E-34 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Gene3D G3DSA:3.40.50.300 157 343 1.1E-24 T 29-03-2018 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 3.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 3.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 3.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 3.2E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Gene3D G3DSA:1.10.8.60 756 847 6.4E-24 T 29-03-2018 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 757 835 2.1E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.9E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS02780 4f8b68193101c0a7ad4e6d11f38f6c81 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 2.7E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MSG_RS10840 0bdfbf84156fb9c5af89e4a99e827127 364 Gene3D G3DSA:3.90.25.10 200 353 1.4E-27 T 29-03-2018 MSG_RS10840 0bdfbf84156fb9c5af89e4a99e827127 364 SUPERFAMILY SSF51735 15 335 1.6E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10840 0bdfbf84156fb9c5af89e4a99e827127 364 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 13 337 4.9E-143 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 MSG_RS10840 0bdfbf84156fb9c5af89e4a99e827127 364 Pfam PF16363 GDP-mannose 4,6 dehydratase 19 327 4.4E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10840 0bdfbf84156fb9c5af89e4a99e827127 364 Gene3D G3DSA:3.40.50.720 8 199 2.2E-29 T 29-03-2018 MSG_RS13660 b85faee28a81e362650655a84bc43ee6 214 ProSitePatterns PS00155 Cutinase, serine active site. 108 120 - T 29-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 MSG_RS13660 b85faee28a81e362650655a84bc43ee6 214 Gene3D G3DSA:3.40.50.1820 22 214 2.5E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13660 b85faee28a81e362650655a84bc43ee6 214 SUPERFAMILY SSF53474 23 213 1.27E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13660 b85faee28a81e362650655a84bc43ee6 214 Pfam PF01083 Cutinase 34 213 9.7E-61 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS13660 b85faee28a81e362650655a84bc43ee6 214 SMART SM01110 33 213 8.0E-91 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS17440 70c9cde7b2d05f8aacb4fea4b6664d7b 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 224 2.1E-44 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS17440 70c9cde7b2d05f8aacb4fea4b6664d7b 256 SUPERFAMILY SSF52096 3 245 9.13E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS17440 70c9cde7b2d05f8aacb4fea4b6664d7b 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS17440 70c9cde7b2d05f8aacb4fea4b6664d7b 256 Gene3D G3DSA:3.90.226.10 1 256 6.3E-56 T 29-03-2018 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Pfam PF10509 Galactokinase galactose-binding signature 5 39 1.7E-15 T 29-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Pfam PF08544 GHMP kinases C terminal 262 338 2.2E-13 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 SUPERFAMILY SSF54211 3 182 1.75E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 TIGRFAM TIGR00131 gal_kin: galactokinase 4 339 1.4E-81 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Hamap MF_00246 Galactokinase [galK]. 7 361 39.22 T 29-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 SUPERFAMILY SSF55060 187 360 4.96E-47 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Gene3D G3DSA:3.30.230.10 1 188 2.6E-51 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00959 Mevalonate kinase family signature 7 31 4.7E-39 T 29-03-2018 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00959 Mevalonate kinase family signature 98 120 4.7E-39 T 29-03-2018 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00959 Mevalonate kinase family signature 308 325 4.7E-39 T 29-03-2018 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00959 Mevalonate kinase family signature 141 160 4.7E-39 T 29-03-2018 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00473 Galactokinase signature 245 259 4.2E-22 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00473 Galactokinase signature 9 27 4.2E-22 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00473 Galactokinase signature 91 109 4.2E-22 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PRINTS PR00473 Galactokinase signature 71 82 4.2E-22 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Gene3D G3DSA:3.30.70.890 189 360 3.6E-51 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 PIRSF PIRSF000530 2 363 3.8E-105 T 29-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 Pfam PF00288 GHMP kinases N terminal domain 95 160 1.1E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MSG_RS03995 ac3be5b645551349df3676e7715e0824 373 ProSitePatterns PS00106 Galactokinase signature. 9 20 - T 29-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 SUPERFAMILY SSF53383 18 361 7.56E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 Gene3D G3DSA:3.90.1150.10 266 362 3.7E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 360 5.5E-181 T 29-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 Pfam PF00155 Aminotransferase class I and II 27 360 9.1E-42 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 Gene3D G3DSA:3.40.640.10 34 265 3.6E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS19075 168b6b8184f0ac19cc88765ad11a8234 366 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Gene3D G3DSA:1.10.1140.10 365 475 1.2E-37 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 1.8E-62 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 SUPERFAMILY SSF50615 15 90 6.28E-24 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Gene3D G3DSA:3.40.50.300 92 364 2.8E-86 T 29-03-2018 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 15 477 7.7E-247 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 SMART SM00382 158 343 6.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Gene3D G3DSA:2.40.10.170 6 91 5.5E-29 T 29-03-2018 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Hamap MF_01347 ATP synthase subunit beta [atpB]. 13 477 54.329 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 SUPERFAMILY SSF52540 93 364 1.47E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 SUPERFAMILY SSF47917 362 477 1.23E-47 T 29-03-2018 MSG_RS18245 09ff9907f6d0e54b130847e516f8d565 481 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 89 3.8E-21 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 SUPERFAMILY SSF51735 7 247 6.39E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.1E-53 T 29-03-2018 MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 8.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 Gene3D G3DSA:3.40.50.720 1 48 5.0E-11 T 29-03-2018 MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 Gene3D G3DSA:3.40.50.720 49 254 3.6E-51 T 29-03-2018 MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00505 bd31cfe12c05ade4a20ef619c5ebfba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12850 2518de0c51dd6f796a6fe0120c4eaa4c 172 Gene3D G3DSA:1.10.10.10 1 130 8.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12850 2518de0c51dd6f796a6fe0120c4eaa4c 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 46 80 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MSG_RS12850 2518de0c51dd6f796a6fe0120c4eaa4c 172 SMART SM00347 5 109 1.3E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS12850 2518de0c51dd6f796a6fe0120c4eaa4c 172 Pfam PF12802 MarR family 10 71 8.2E-14 T 29-03-2018 MSG_RS12850 2518de0c51dd6f796a6fe0120c4eaa4c 172 SUPERFAMILY SSF46785 4 120 1.65E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 135 147 - T 29-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 Gene3D G3DSA:3.30.200.20 7 111 5.0E-18 T 29-03-2018 MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 Pfam PF00069 Protein kinase domain 16 208 2.1E-34 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 SUPERFAMILY SSF56112 13 258 8.63E-59 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 Gene3D G3DSA:1.10.510.10 112 262 2.1E-33 T 29-03-2018 MSG_RS15945 ada6cdba8058a2c8991e597410a93923 513 SMART SM00219 16 259 2.5E-7 T 29-03-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 Gene3D G3DSA:3.30.230.40 4 90 5.8E-32 T 29-03-2018 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 SUPERFAMILY SSF54211 4 88 8.09E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 165 177 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 SUPERFAMILY SSF54211 89 188 6.07E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 Gene3D G3DSA:3.30.230.40 92 203 1.4E-33 T 29-03-2018 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 203 41.457 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MSG_RS11165 8ec394167fa465e1a7748e6a5cf1d85e 203 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 183 9.4E-57 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MSG_RS00220 192f9f7fdb3e6634a8c5f76d7db4bbdd 109 Pfam PF10921 Protein of unknown function (DUF2710) 3 106 3.5E-53 T 29-03-2018 IPR024296 Protein of unknown function DUF2710 MSG_RS00220 192f9f7fdb3e6634a8c5f76d7db4bbdd 109 Gene3D G3DSA:3.30.1310.10 20 106 8.9E-9 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS00220 192f9f7fdb3e6634a8c5f76d7db4bbdd 109 ProDom PD071857 MB0031 RV0030/MT0034 7 108 2.0E-31 T 29-03-2018 IPR024296 Protein of unknown function DUF2710 MSG_RS20310 c7e32de30753b14195a9b62189313bc4 464 Pfam PF00158 Sigma-54 interaction domain 175 232 3.6E-5 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MSG_RS20310 c7e32de30753b14195a9b62189313bc4 464 Gene3D G3DSA:3.40.50.300 51 265 1.2E-13 T 29-03-2018 MSG_RS20310 c7e32de30753b14195a9b62189313bc4 464 SUPERFAMILY SSF52540 53 339 8.38E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 119 157 2.1E-5 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 46 4.1E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 Gene3D G3DSA:3.40.1620.10 65 107 1.0E-7 T 29-03-2018 MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 Gene3D G3DSA:3.40.1620.10 3 47 7.6E-9 T 29-03-2018 MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 Gene3D G3DSA:3.40.1620.10 117 158 1.5E-7 T 29-03-2018 MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 SUPERFAMILY SSF143120 4 46 2.49E-5 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 119 158 1.3E-5 T 29-03-2018 MSG_RS14285 90633a63a9db3e4c332a492a2ad39eac 164 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 46 3.3E-5 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 154 1.8E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Gene3D G3DSA:3.40.50.300 17 297 1.2E-36 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Pfam PF00009 Elongation factor Tu GTP binding domain 23 290 2.5E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF54211 507 622 1.49E-37 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SMART SM00838 627 715 7.5E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF54980 630 716 8.63E-22 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF50447 314 428 2.26E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF50447 258 284 2.26E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Pfam PF14492 Elongation Factor G, domain II 431 503 1.9E-23 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Gene3D G3DSA:3.30.70.240 636 714 1.0E-21 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF54980 431 508 3.5E-17 T 29-03-2018 IPR035647 EF-G domain III/V-like MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SUPERFAMILY SSF52540 20 291 3.08E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 SMART SM00889 507 625 1.6E-60 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Pfam PF00679 Elongation factor G C-terminus 628 714 8.2E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Pfam PF03144 Elongation factor Tu domain 2 333 417 2.9E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Gene3D G3DSA:3.30.70.870 428 518 7.1E-19 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Pfam PF03764 Elongation factor G, domain IV 507 623 1.3E-41 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Gene3D G3DSA:2.40.30.10 303 427 2.7E-29 T 29-03-2018 MSG_RS01225 adb3a20603d192eff5a22d64804ed630 719 Gene3D G3DSA:3.30.230.10 519 635 1.4E-39 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 Pfam PF02863 Arginine repressor, C-terminal domain 97 163 7.0E-23 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 Pfam PF01316 Arginine repressor, DNA binding domain 12 81 3.8E-25 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 SUPERFAMILY SSF55252 97 164 3.14E-17 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 Gene3D G3DSA:3.30.1360.40 91 162 8.9E-29 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 Hamap MF_00173 Arginine repressor [argR]. 1 166 59.334 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 105 163 1.0E-18 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 PRINTS PR01467 Bacterial arginine repressor signature 105 118 4.8E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 PRINTS PR01467 Bacterial arginine repressor signature 32 45 4.8E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 PRINTS PR01467 Bacterial arginine repressor signature 135 150 4.8E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 PRINTS PR01467 Bacterial arginine repressor signature 48 63 4.8E-27 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 SUPERFAMILY SSF46785 13 81 3.54E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 Gene3D G3DSA:1.10.10.10 14 78 9.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11520 d29dc2a0b962a5aff72d8ad293fd705d 166 TIGRFAM TIGR01529 argR_whole: arginine repressor 16 165 1.4E-46 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MSG_RS05325 8d17244e83b7cfc55d1a43eaa8fe7b6d 457 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 315 390 1.4E-7 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS05325 8d17244e83b7cfc55d1a43eaa8fe7b6d 457 SUPERFAMILY SSF140459 2 172 6.8E-66 T 29-03-2018 MSG_RS05325 8d17244e83b7cfc55d1a43eaa8fe7b6d 457 Gene3D G3DSA:1.10.287.1060 22 102 4.4E-8 T 29-03-2018 MSG_RS05325 8d17244e83b7cfc55d1a43eaa8fe7b6d 457 Pfam PF00823 PPE family 6 160 7.7E-64 T 29-03-2018 IPR000030 PPE family MSG_RS12485 22331a257853baea187060d75322474a 233 Gene3D G3DSA:3.40.50.1820 2 207 9.0E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12485 22331a257853baea187060d75322474a 233 SMART SM01110 12 203 3.9E-88 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS12485 22331a257853baea187060d75322474a 233 SUPERFAMILY SSF53474 13 203 2.24E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12485 22331a257853baea187060d75322474a 233 Pfam PF01083 Cutinase 13 202 4.5E-46 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 SMART SM00478 41 192 1.4E-43 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 Gene3D G3DSA:1.10.1670.10 120 226 3.5E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 Gene3D G3DSA:1.10.340.30 22 119 3.8E-29 T 29-03-2018 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 Pfam PF00633 Helix-hairpin-helix motif 102 130 9.9E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 SUPERFAMILY SSF48150 10 209 1.88E-60 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 37 150 4.2E-15 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS22765 73bc21a9ece6be94541a284529a82f6a 294 SMART SM00525 193 212 0.0033 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MSG_RS10655 c5c89c5a1afa61f8aeb8cbe6f045a2b1 377 SUPERFAMILY SSF52540 49 324 4.52E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10655 c5c89c5a1afa61f8aeb8cbe6f045a2b1 377 PIRSF PIRSF002849 26 354 5.3E-135 T 29-03-2018 MSG_RS10655 c5c89c5a1afa61f8aeb8cbe6f045a2b1 377 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 73 203 1.7E-59 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MSG_RS10655 c5c89c5a1afa61f8aeb8cbe6f045a2b1 377 Gene3D G3DSA:3.40.50.300 54 220 2.4E-26 T 29-03-2018 MSG_RS10655 c5c89c5a1afa61f8aeb8cbe6f045a2b1 377 Gene3D G3DSA:1.10.8.300 232 349 1.2E-30 T 29-03-2018 MSG_RS20290 c205d6d4239e3c241bd2959d0cde26e7 555 SUPERFAMILY SSF53474 387 456 2.98E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20290 c205d6d4239e3c241bd2959d0cde26e7 555 Gene3D G3DSA:1.10.287.1060 10 110 1.9E-4 T 29-03-2018 MSG_RS20290 c205d6d4239e3c241bd2959d0cde26e7 555 Pfam PF06259 Alpha/beta hydrolase 291 466 7.9E-58 T 29-03-2018 IPR010427 Protein of unknown function DUF1023 MSG_RS20290 c205d6d4239e3c241bd2959d0cde26e7 555 Gene3D G3DSA:3.40.50.1820 286 527 1.3E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 Gene3D G3DSA:1.10.730.10 347 512 1.1E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 Pfam PF09334 tRNA synthetases class I (M) 4 362 9.6E-110 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 SUPERFAMILY SSF47323 355 512 3.18E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 511 46.63 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 Gene3D G3DSA:3.40.50.620 1 346 4.1E-97 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 484 4.0E-146 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 SUPERFAMILY SSF52374 3 353 2.41E-110 T 29-03-2018 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 225 236 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS19950 cd502da5fc1bf68cfd908e5903db6e04 517 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 8.9E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 SUPERFAMILY SSF53223 763 958 1.92E-21 T 29-03-2018 MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 Gene3D G3DSA:3.40.50.10860 790 922 0.0023 T 29-03-2018 MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 Gene3D G3DSA:3.40.50.720 940 1285 7.4E-50 T 29-03-2018 MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 PIRSF PIRSF036761 1 1609 0.0 T 29-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 SUPERFAMILY SSF51735 947 1049 1.71E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 SUPERFAMILY SSF51735 1087 1214 1.71E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17315 c6559b078e0b9390f5d2745d887a616b 1614 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 97 1602 0.0 T 29-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MSG_RS02505 9c584601a67f15ec32a800ddcef35e17 139 SMART SM00347 26 126 1.6E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS02505 9c584601a67f15ec32a800ddcef35e17 139 Pfam PF01047 MarR family 35 81 1.4E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS02505 9c584601a67f15ec32a800ddcef35e17 139 SUPERFAMILY SSF46785 6 134 4.56E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02505 9c584601a67f15ec32a800ddcef35e17 139 Gene3D G3DSA:1.10.10.10 2 137 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 8.7E-5 T 29-03-2018 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 8.7E-5 T 29-03-2018 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 8.7E-5 T 29-03-2018 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 SUPERFAMILY SSF51905 149 386 3.31E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 Gene3D G3DSA:3.50.50.60 165 542 1.2E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 Gene3D G3DSA:3.50.50.60 4 164 8.2E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 SUPERFAMILY SSF51905 323 539 6.19E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 SUPERFAMILY SSF51905 8 225 1.15E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17865 9d0c75dff30c9ed5a1ea025d9c1d387b 542 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 192 1.2E-12 T 29-03-2018 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 265 276 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Pfam PF00501 AMP-binding enzyme 91 535 4.5E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 83 7.2E-20 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 25 654 1.2E-281 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 656 49.472 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Gene3D G3DSA:3.40.50.980 76 270 1.6E-47 T 29-03-2018 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Gene3D G3DSA:3.40.50.980 271 433 2.6E-35 T 29-03-2018 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Gene3D G3DSA:2.30.38.10 434 528 2.0E-15 T 29-03-2018 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Gene3D G3DSA:3.30.300.30 529 641 2.6E-27 T 29-03-2018 MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 622 1.7E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS23090 7301c451f2153c7e4f61925f93fbfa36 656 SUPERFAMILY SSF56801 28 652 2.22E-166 T 29-03-2018 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 15 375 38.702 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 SUPERFAMILY SSF51246 318 401 2.35E-14 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 Gene3D G3DSA:3.30.1490.20 94 192 1.7E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 Pfam PF02222 ATP-grasp domain 121 293 5.7E-56 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 Gene3D G3DSA:3.40.50.20 14 93 8.3E-20 T 29-03-2018 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 SUPERFAMILY SSF52440 12 107 4.6E-20 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 SUPERFAMILY SSF56059 112 313 1.11E-59 T 29-03-2018 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 16 373 4.3E-124 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MSG_RS05725 a95929ca773c30970bc808bda70f6d84 420 Gene3D G3DSA:3.30.470.20 193 396 4.6E-44 T 29-03-2018 MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 Gene3D G3DSA:3.40.1160.10 10 263 3.9E-48 T 29-03-2018 MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 Pfam PF00696 Amino acid kinase family 34 241 1.8E-31 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 SUPERFAMILY SSF53633 30 262 1.27E-71 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 Hamap MF_01220_B Uridylate kinase [pyrH]. 30 262 42.101 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 PIRSF PIRSF005650 28 263 1.1E-85 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MSG_RS08355 bd9d08d785a41a15ca24aae6e3bf4806 263 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 32 262 2.6E-86 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 SUPERFAMILY SSF46785 7 75 2.06E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 Gene3D G3DSA:3.30.450.40 72 233 1.7E-36 T 29-03-2018 IPR029016 GAF domain-like MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 Pfam PF09339 IclR helix-turn-helix domain 10 58 5.6E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 SMART SM00346 7 92 4.4E-24 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 Gene3D G3DSA:1.10.10.10 1 71 8.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 9.6E-18 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal MSG_RS07825 0ab353d9d95015e6e17308004b39a545 233 SUPERFAMILY SSF55781 62 233 1.9E-36 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11765 bbf2b810c22a2faca80a296a69d989e5 227 Pfam PF02224 Cytidylate kinase 6 221 1.9E-79 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MSG_RS11765 bbf2b810c22a2faca80a296a69d989e5 227 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 32.965 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MSG_RS11765 bbf2b810c22a2faca80a296a69d989e5 227 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 217 2.2E-68 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MSG_RS11765 bbf2b810c22a2faca80a296a69d989e5 227 SUPERFAMILY SSF52540 1 222 7.26E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11765 bbf2b810c22a2faca80a296a69d989e5 227 Gene3D G3DSA:3.40.50.300 1 223 2.4E-50 T 29-03-2018 MSG_RS17790 6df6f2f334ef2968a6084520198166bc 321 Gene3D G3DSA:3.40.50.1820 10 312 1.6E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17790 6df6f2f334ef2968a6084520198166bc 321 SUPERFAMILY SSF53474 66 318 3.04E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17790 6df6f2f334ef2968a6084520198166bc 321 Pfam PF07859 alpha/beta hydrolase fold 92 294 2.8E-50 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Gene3D G3DSA:3.20.20.60 159 319 6.7E-63 T 29-03-2018 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Gene3D G3DSA:3.20.20.60 1 75 2.5E-16 T 29-03-2018 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 267 291 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 185 199 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 215 241 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 60 76 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 242 266 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 292 310 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 PRINTS PR01050 Pyruvate kinase family signature 311 327 8.9E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 1.1E-165 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 SUPERFAMILY SSF52935 322 468 1.2E-34 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 354 465 6.0E-24 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 SUPERFAMILY SSF51621 166 335 2.69E-94 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 SUPERFAMILY SSF51621 2 76 2.69E-94 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Gene3D G3DSA:3.40.1380.20 320 468 1.5E-40 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Gene3D G3DSA:2.40.33.10 76 158 5.9E-24 T 29-03-2018 MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 SUPERFAMILY SSF50800 71 165 6.11E-23 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MSG_RS11255 4f90511c42ad9a82f6e467bdadbfe45e 472 Pfam PF00224 Pyruvate kinase, barrel domain 3 335 1.3E-115 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS05955 8102d7c6609dca8b5662af319aa1bf4a 469 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 271 7.4E-82 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS05955 8102d7c6609dca8b5662af319aa1bf4a 469 Pfam PF06974 Protein of unknown function (DUF1298) 323 464 4.5E-21 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS05955 8102d7c6609dca8b5662af319aa1bf4a 469 SUPERFAMILY SSF52777 28 159 2.33E-6 T 29-03-2018 MSG_RS05955 8102d7c6609dca8b5662af319aa1bf4a 469 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 467 2.0E-146 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS05955 8102d7c6609dca8b5662af319aa1bf4a 469 Gene3D G3DSA:3.30.559.10 4 174 0.0012 T 29-03-2018 MSG_RS24040 4d6298c348eabea0e499ab678cef8f12 278 SMART SM00382 61 250 1.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24040 4d6298c348eabea0e499ab678cef8f12 278 Pfam PF00005 ABC transporter 52 182 4.1E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS24040 4d6298c348eabea0e499ab678cef8f12 278 Gene3D G3DSA:3.40.50.300 5 277 1.7E-38 T 29-03-2018 MSG_RS24040 4d6298c348eabea0e499ab678cef8f12 278 SUPERFAMILY SSF52540 50 246 8.47E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Gene3D G3DSA:1.10.287.130 612 684 5.0E-13 T 29-03-2018 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 SMART SM00387 738 847 1.9E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 SUPERFAMILY SSF47384 613 690 3.14E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Pfam PF00582 Universal stress protein family 243 356 2.5E-10 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 13 222 7.3E-98 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Gene3D G3DSA:3.30.565.10 685 845 3.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 740 843 2.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Gene3D G3DSA:3.40.50.620 226 371 2.1E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 SUPERFAMILY SSF52402 243 364 1.16E-16 T 29-03-2018 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 SMART SM00388 622 690 1.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Pfam PF00512 His Kinase A (phospho-acceptor) domain 623 690 2.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 788 4.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 807 825 4.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 831 844 4.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 802 4.0E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Gene3D G3DSA:3.40.50.300 13 141 8.9E-22 T 29-03-2018 MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 SUPERFAMILY SSF55874 680 843 1.31E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Pfam PF13493 Domain of unknown function (DUF4118) 388 495 9.7E-24 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MSG_RS19820 6ff3c55317cfe59fe5c8e09bbe7ba94c 851 Gene3D G3DSA:1.20.120.620 387 487 2.4E-20 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 Gene3D G3DSA:1.20.1110.10 37 401 1.5E-32 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 545 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 624 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 523 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 607 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 386 400 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 244 258 2.0E-26 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 SUPERFAMILY SSF81653 198 293 1.11E-20 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 145 691 1.2E-168 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 Gene3D G3DSA:3.40.1110.10 402 508 2.4E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 560 576 9.5E-5 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 588 604 9.5E-5 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 Gene3D G3DSA:3.40.50.1000 509 661 1.9E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 SUPERFAMILY SSF56784 444 688 4.67E-53 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 SUPERFAMILY SSF56784 385 404 4.67E-53 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 Pfam PF00702 haloacid dehalogenase-like hydrolase 382 602 1.2E-41 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 Pfam PF00122 E1-E2 ATPase 197 366 4.0E-41 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 126 691 1.5E-125 T 29-03-2018 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 168 669 4.2E-72 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05775 d5008cb77186c5f1cd80ea5d91ecd906 707 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 388 394 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 Gene3D G3DSA:3.40.50.10540 6 373 5.8E-70 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 Gene3D G3DSA:3.40.50.10540 384 793 1.1E-114 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 Pfam PF02515 CoA-transferase family III 390 763 6.8E-101 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 Pfam PF02515 CoA-transferase family III 12 358 1.6E-54 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 SUPERFAMILY SSF89796 385 787 7.98E-108 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17705 63466b614a6975dde0582a3d48eec015 794 SUPERFAMILY SSF89796 10 371 4.19E-66 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS24200 976679972e5f1ce148d1973e60255d5d 173 SMART SM00014 62 166 1.7E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS24200 976679972e5f1ce148d1973e60255d5d 173 Gene3D G3DSA:1.20.144.10 3 173 1.1E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS24200 976679972e5f1ce148d1973e60255d5d 173 SUPERFAMILY SSF48317 6 168 4.45E-33 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS24200 976679972e5f1ce148d1973e60255d5d 173 Pfam PF01569 PAP2 superfamily 64 171 6.1E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 Gene3D G3DSA:3.40.50.1820 8 304 9.2E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 SUPERFAMILY SSF53474 34 301 2.54E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 Pfam PF12697 Alpha/beta hydrolase family 58 293 1.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 94 6.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 6.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00315 d46573a0eb94a58ad7c0c9b350dbfa5e 304 PRINTS PR00111 Alpha/beta hydrolase fold signature 138 151 6.9E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 58 240 2.2E-65 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 Gene3D G3DSA:1.10.10.730 155 202 2.9E-17 T 29-03-2018 MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 SUPERFAMILY SSF110849 55 157 2.44E-29 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 Gene3D G3DSA:3.90.1530.10 56 154 1.1E-36 T 29-03-2018 MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 Pfam PF02195 ParB-like nuclease domain 62 154 1.1E-25 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 SUPERFAMILY SSF109709 146 255 1.27E-31 T 29-03-2018 MSG_RS24680 3ec4a087d0411e0e41f214c84bde4d98 326 SMART SM00470 61 154 2.0E-36 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 SUPERFAMILY SSF54814 263 327 1.24E-16 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 343 26.186 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 SUPERFAMILY SSF69705 1 99 4.58E-28 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Gene3D G3DSA:3.30.300.20 262 333 2.2E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Gene3D G3DSA:3.30.1480.10 1 99 4.1E-28 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 SUPERFAMILY SSF50249 109 183 7.62E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Pfam PF13184 NusA-like KH domain 214 281 4.4E-26 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Gene3D G3DSA:3.30.300.20 183 260 1.5E-32 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 SUPERFAMILY SSF54814 184 262 8.5E-28 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Pfam PF08529 NusA N-terminal domain 60 100 2.9E-6 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Pfam PF08529 NusA N-terminal domain 6 60 5.1E-8 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 Gene3D G3DSA:2.40.50.140 112 182 6.0E-11 T 29-03-2018 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 76 326 2.7E-100 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 MSG_RS08525 e1fff0b286cfcfcac98bf73a7d3200cc 347 SMART SM00316 110 182 0.0025 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 53 523 2.1E-149 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Pfam PF02875 Mur ligase family, glutamate ligase domain 369 453 1.6E-21 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Gene3D G3DSA:3.40.1190.10 134 373 1.6E-60 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 SUPERFAMILY SSF53623 134 364 1.26E-66 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Pfam PF08245 Mur ligase middle domain 143 349 6.9E-46 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 SUPERFAMILY SSF63418 48 132 5.23E-17 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 31 523 31.972 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Gene3D G3DSA:3.90.190.20 374 530 7.1E-46 T 29-03-2018 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Gene3D G3DSA:3.40.1390.10 30 133 7.0E-21 T 29-03-2018 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 Pfam PF01225 Mur ligase family, catalytic domain 55 130 3.4E-9 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MSG_RS15115 b8b3c860dcbdb94ebc8fdff35d4ce758 530 SUPERFAMILY SSF53244 369 524 8.37E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 SUPERFAMILY SSF55781 73 341 2.75E-54 T 29-03-2018 IPR029016 GAF domain-like MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 SUPERFAMILY SSF46785 5 84 6.98E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 Gene3D G3DSA:1.10.10.10 1 86 1.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 333 27.223 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 Pfam PF01628 HrcA protein C terminal domain 105 326 1.6E-61 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 PIRSF PIRSF005485 1 343 2.8E-104 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 Gene3D G3DSA:3.30.450.40 173 343 7.8E-35 T 29-03-2018 IPR029016 GAF domain-like MSG_RS16730 faff3e8e9e76da2551f5b781ceb2687b 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 338 2.5E-87 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 SUPERFAMILY SSF46689 23 95 7.7E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 Gene3D G3DSA:1.10.10.60 65 87 6.4E-8 T 29-03-2018 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 Gene3D G3DSA:1.10.10.60 19 64 1.0E-16 T 29-03-2018 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 76 9.1E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 Gene3D G3DSA:1.10.357.10 88 220 2.9E-5 T 29-03-2018 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 8.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01310 e6e8ad1d48599fb8c548d6e112d84a37 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 8.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10140 f3e4f01537461e8354cf982b08f177e7 218 Pfam PF00694 Aconitase C-terminal domain 1 124 4.4E-28 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10140 f3e4f01537461e8354cf982b08f177e7 218 Gene3D G3DSA:3.20.19.10 1 178 8.3E-39 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS10140 f3e4f01537461e8354cf982b08f177e7 218 SUPERFAMILY SSF52016 1 194 1.24E-47 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS10140 f3e4f01537461e8354cf982b08f177e7 218 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 1.7E-52 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 320 8.2E-157 T 29-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 Gene3D G3DSA:2.160.10.10 154 279 3.9E-18 T 29-03-2018 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 Gene3D G3DSA:3.30.60.70 114 153 1.0E-19 T 29-03-2018 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 114 153 2.6E-19 T 29-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 SUPERFAMILY SSF51161 73 300 2.08E-40 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 318 43.834 T 29-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 MSG_RS18905 9d88ac2178c00290b4663d3506d7e5ad 320 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 235 267 1.4E-15 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 Pfam PF00106 short chain dehydrogenase 7 199 4.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 192 6.6E-4 T 29-03-2018 MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 Gene3D G3DSA:3.40.50.720 1 250 4.3E-55 T 29-03-2018 MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 SUPERFAMILY SSF51735 7 246 1.01E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19215 63fc0d559f9cc5eeb3f360a0519afb84 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.3E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09890 fee2480e387ecee2d0f4fc3495fd7d35 415 Pfam PF02618 YceG-like family 83 402 1.3E-58 T 29-03-2018 IPR003770 Endolytic murein transglycosylase MSG_RS09890 fee2480e387ecee2d0f4fc3495fd7d35 415 Gene3D G3DSA:3.30.160.60 376 407 5.2E-8 T 29-03-2018 MSG_RS09890 fee2480e387ecee2d0f4fc3495fd7d35 415 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 44 406 26.756 T 29-03-2018 IPR003770 Endolytic murein transglycosylase MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 140 8.2E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 143 61.58 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 SUPERFAMILY SSF52304 1 140 3.27E-53 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 140 1.0E-65 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 PIRSF PIRSF001399 1 143 4.7E-55 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 Pfam PF01220 Dehydroquinase class II 4 139 8.1E-53 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS09925 4ef6ed7065fe384bbf20b1327259f38f 143 Gene3D G3DSA:3.40.50.9100 1 143 2.7E-56 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Gene3D G3DSA:3.30.1490.20 21 87 3.9E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 255 279 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 391 1.5E-119 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 SUPERFAMILY SSF52210 237 391 2.22E-40 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 392 36.845 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 PIRSF PIRSF001554 1 393 1.8E-133 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Pfam PF00549 CoA-ligase 262 377 7.1E-14 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Pfam PF08442 ATP-grasp domain 2 194 6.9E-70 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 SUPERFAMILY SSF56059 1 232 2.83E-62 T 29-03-2018 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Gene3D G3DSA:3.40.50.261 238 391 1.9E-35 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20350 372cdfd1384dbeca61148df25a5cbbf0 393 Gene3D G3DSA:3.30.470.20 88 237 8.0E-46 T 29-03-2018 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 311 1.0E-72 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 17 788 2.7E-276 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 SUPERFAMILY SSF52540 15 701 2.55E-173 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Pfam PF13361 UvrD-like helicase C-terminal domain 317 672 1.6E-67 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Gene3D G3DSA:3.40.50.300 463 717 1.6E-49 T 29-03-2018 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Gene3D G3DSA:3.40.50.300 13 156 2.2E-27 T 29-03-2018 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Gene3D G3DSA:3.40.50.300 157 321 6.2E-33 T 29-03-2018 MSG_RS20365 725d84ee35aa44d7087b195a2632e6d0 791 Gene3D G3DSA:3.40.50.300 322 425 3.1E-28 T 29-03-2018 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 SUPERFAMILY SSF55666 157 245 2.09E-21 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 6.2E-26 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 SUPERFAMILY SSF54211 3 184 1.77E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 Gene3D G3DSA:3.30.230.70 1 241 6.7E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 Hamap MF_00564 Ribonuclease PH [rph]. 3 240 45.682 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 ProSitePatterns PS01277 Ribonuclease PH signature. 118 131 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 Pfam PF03725 3' exoribonuclease family, domain 2 161 225 1.1E-9 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MSG_RS18070 dafd866c5578cc2be0dd3c99c05f7616 259 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 4 239 1.2E-103 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 SUPERFAMILY SSF48264 40 429 3.93E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 370 379 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 303 314 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 179 194 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 113 124 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 162 178 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 221 243 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 348 363 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 379 390 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 PRINTS PR00359 B-class P450 signature 320 347 7.4E-48 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 Pfam PF00067 Cytochrome P450 109 393 2.6E-18 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15840 fe7f3fba0d2c5fb4a08b63baa73f67b1 435 Gene3D G3DSA:1.10.630.10 1 428 1.0E-74 T 29-03-2018 MSG_RS18230 c7c82a25ab5f2cabfe9dc1c697a4d569 191 Gene3D G3DSA:1.20.1200.10 17 190 9.9E-56 T 29-03-2018 MSG_RS18230 c7c82a25ab5f2cabfe9dc1c697a4d569 191 Pfam PF01923 Cobalamin adenosyltransferase 8 175 2.2E-57 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MSG_RS18230 c7c82a25ab5f2cabfe9dc1c697a4d569 191 SUPERFAMILY SSF89028 7 185 2.75E-56 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MSG_RS18230 c7c82a25ab5f2cabfe9dc1c697a4d569 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 146 2.0E-60 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MSG_RS18230 c7c82a25ab5f2cabfe9dc1c697a4d569 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 8.4E-49 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 PRINTS PR01217 Proline rich extensin signature 214 239 7.0E-14 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 PRINTS PR01217 Proline rich extensin signature 184 201 7.0E-14 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 PRINTS PR01217 Proline rich extensin signature 123 135 7.0E-14 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 PRINTS PR01217 Proline rich extensin signature 135 156 7.0E-14 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 PRINTS PR01217 Proline rich extensin signature 164 180 7.0E-14 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 594 6.0E-138 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 Pfam PF02355 Protein export membrane protein 422 596 7.6E-8 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 SUPERFAMILY SSF82866 400 597 4.84E-24 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 351 586 1.5E-70 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 Pfam PF07549 SecD/SecF GG Motif 39 57 7.2E-4 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 Gene3D G3DSA:1.20.1640.10 393 600 7.7E-24 T 29-03-2018 MSG_RS09700 8b9993d29d5b7c0b7a4f836b79d309ef 632 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 607 38.169 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 Gene3D G3DSA:3.40.50.720 47 256 8.1E-60 T 29-03-2018 MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 Gene3D G3DSA:3.40.50.720 2 46 1.9E-6 T 29-03-2018 MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 1.1E-58 T 29-03-2018 MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 SUPERFAMILY SSF51735 9 248 6.8E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS09475 e4b99df3d6346ff85791c21d534fb243 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Gene3D G3DSA:3.40.50.980 5 192 9.1E-31 T 29-03-2018 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Gene3D G3DSA:2.30.38.10 364 451 2.7E-7 T 29-03-2018 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 SUPERFAMILY SSF56801 6 554 2.62E-98 T 29-03-2018 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Gene3D G3DSA:3.40.50.980 193 363 1.2E-25 T 29-03-2018 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 467 542 1.1E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Gene3D G3DSA:3.30.300.30 454 554 8.9E-25 T 29-03-2018 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 Pfam PF00501 AMP-binding enzyme 18 457 1.4E-48 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS17880 3f2210f0459f11b158c5503643fb37d7 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 968 1243 1.6E-120 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SUPERFAMILY SSF51717 374 648 5.63E-89 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Gene3D G3DSA:3.10.196.10 987 1263 4.8E-105 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Gene3D G3DSA:3.20.20.20 363 662 1.6E-72 T 29-03-2018 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Pfam PF02607 B12 binding domain 675 752 1.4E-23 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Pfam PF02574 Homocysteine S-methyltransferase 37 343 1.5E-75 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Gene3D G3DSA:3.20.20.330 23 356 3.2E-109 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SUPERFAMILY SSF47644 669 759 7.45E-26 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Pfam PF02310 B12 binding domain 778 868 1.9E-19 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Gene3D G3DSA:3.40.50.280 773 925 4.2E-55 T 29-03-2018 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Gene3D G3DSA:1.10.1240.10 668 757 1.0E-34 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SUPERFAMILY SSF82282 31 417 6.41E-113 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 TIGRFAM TIGR02082 metH: methionine synthase 32 1227 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SUPERFAMILY SSF52242 774 924 7.2E-45 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SMART SM01018 673 760 1.6E-41 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 Pfam PF00809 Pterin binding enzyme 378 616 2.5E-58 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 PIRSF PIRSF000381 22 1230 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS14880 a97524241ad07442c033966adf450e23 1263 SUPERFAMILY SSF56507 931 1262 8.37E-128 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS03065 d7b7cf35918a295300b68dc0a33b02b5 486 SUPERFAMILY SSF55486 28 248 6.67E-19 T 29-03-2018 MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 Pfam PF00106 short chain dehydrogenase 10 196 9.1E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 SUPERFAMILY SSF51735 8 232 1.19E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00490 87843747795fbf9c4d991fc86a35b8c6 263 Gene3D G3DSA:3.40.50.720 7 252 2.5E-39 T 29-03-2018 MSG_RS02295 b54396794e821c5ce966469c4e1b935e 130 Gene3D G3DSA:1.10.10.10 10 115 3.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 SUPERFAMILY SSF54686 1 136 2.75E-55 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.653 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 8.3E-55 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 Gene3D G3DSA:3.90.1170.10 3 138 1.1E-48 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.2E-37 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.2E-37 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.2E-37 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.2E-37 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.5E-47 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MSG_RS04495 b9473dc1203d9953a4516be6bb0e36a9 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 Gene3D G3DSA:3.30.450.40 25 191 2.8E-13 T 29-03-2018 IPR029016 GAF domain-like MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 SMART SM01012 186 241 4.1E-19 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 PIRSF PIRSF036625 1 253 2.5E-71 T 29-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 Gene3D G3DSA:1.10.10.10 192 243 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 Pfam PF13185 GAF domain 43 178 3.0E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 Pfam PF03861 ANTAR domain 189 241 1.2E-15 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 SUPERFAMILY SSF55781 28 179 4.71E-11 T 29-03-2018 IPR029016 GAF domain-like MSG_RS08240 8ff2e2f2c5188ba52b5a2b92ede751d2 257 SUPERFAMILY SSF52172 181 241 4.22E-8 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS04930 d62e74c6aaa17737e9a49a827d70b01a 473 Gene3D G3DSA:1.10.287.1060 54 145 1.9E-4 T 29-03-2018 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 SUPERFAMILY SSF53901 269 390 3.37E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 SUPERFAMILY SSF53901 5 268 5.28E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 6.7E-108 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 Pfam PF00108 Thiolase, N-terminal domain 5 261 4.0E-51 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 Gene3D G3DSA:3.40.47.10 262 391 4.7E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 PIRSF PIRSF000429 1 391 1.7E-111 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 Gene3D G3DSA:3.40.47.10 2 261 2.9E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22505 1f18f4a31a3351f7d45f69f6f953d2df 391 Pfam PF02803 Thiolase, C-terminal domain 268 390 3.4E-38 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS02980 7832d640ed19b5b2a74535014a052208 399 Pfam PF07394 Protein of unknown function (DUF1501) 49 355 3.9E-26 T 29-03-2018 IPR010869 Protein of unknown function DUF1501 MSG_RS02980 7832d640ed19b5b2a74535014a052208 399 Gene3D G3DSA:3.40.720.10 108 397 6.3E-5 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS02980 7832d640ed19b5b2a74535014a052208 399 Gene3D G3DSA:1.20.5.510 2 31 6.4E-4 T 29-03-2018 MSG_RS19230 6601c3c31f0632a8212fa1c4aeb047f0 350 Gene3D G3DSA:3.40.50.720 5 308 2.0E-33 T 29-03-2018 MSG_RS19230 6601c3c31f0632a8212fa1c4aeb047f0 350 SUPERFAMILY SSF51735 6 285 3.34E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19230 6601c3c31f0632a8212fa1c4aeb047f0 350 Pfam PF13460 NAD(P)H-binding 11 156 1.9E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18430 f6dd3e078979a501b548a4be51a512b2 292 Gene3D G3DSA:3.20.20.30 7 292 4.6E-52 T 29-03-2018 MSG_RS18430 f6dd3e078979a501b548a4be51a512b2 292 SUPERFAMILY SSF51679 12 290 3.79E-50 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS18430 f6dd3e078979a501b548a4be51a512b2 292 Pfam PF00296 Luciferase-like monooxygenase 17 241 7.9E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 Pfam PF00884 Sulfatase 33 461 6.0E-94 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 SUPERFAMILY SSF53649 33 571 2.18E-125 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 Gene3D G3DSA:3.40.720.10 30 490 6.6E-94 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 ProSitePatterns PS00149 Sulfatases signature 2. 129 139 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 Gene3D G3DSA:2.60.120.200 500 763 1.7E-7 T 29-03-2018 MSG_RS11625 88eafd8a2ebd0b0f20bd066fd391cd3b 783 ProSitePatterns PS00523 Sulfatases signature 1. 77 89 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS17030 fb547356f5d3646184488e7c5d57c887 291 SMART SM00382 42 205 3.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS17030 fb547356f5d3646184488e7c5d57c887 291 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 194 3.1E-10 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS17030 fb547356f5d3646184488e7c5d57c887 291 Gene3D G3DSA:3.40.50.300 17 235 6.5E-30 T 29-03-2018 MSG_RS17030 fb547356f5d3646184488e7c5d57c887 291 SUPERFAMILY SSF52540 115 280 8.47E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17030 fb547356f5d3646184488e7c5d57c887 291 SUPERFAMILY SSF52540 40 88 8.47E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS15490 349c1dda3f93710cc76249be522a911e 218 Pfam PF03061 Thioesterase superfamily 129 201 2.2E-5 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS15490 349c1dda3f93710cc76249be522a911e 218 SUPERFAMILY SSF54637 15 210 5.08E-36 T 29-03-2018 IPR029069 HotDog domain MSG_RS15490 349c1dda3f93710cc76249be522a911e 218 Gene3D G3DSA:3.10.129.10 17 212 2.1E-19 T 29-03-2018 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 SUPERFAMILY SSF53756 28 837 0.0 T 29-03-2018 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 Gene3D G3DSA:3.40.50.2000 24 503 3.2E-183 T 29-03-2018 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 35 833 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 Gene3D G3DSA:3.40.50.2000 504 818 8.8E-136 T 29-03-2018 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 Pfam PF00343 Carbohydrate phosphorylase 121 833 0.0 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS07195 3728b212896b8d68f7a13f177c3cb8a1 840 PIRSF PIRSF000460 19 840 2.6E-222 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS21570 f146e490a3f22a3b050bd9862f99b8d0 269 SUPERFAMILY SSF53335 4 252 4.18E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS21570 f146e490a3f22a3b050bd9862f99b8d0 269 Pfam PF13847 Methyltransferase domain 37 145 9.1E-27 T 29-03-2018 IPR025714 Methyltransferase domain MSG_RS21570 f146e490a3f22a3b050bd9862f99b8d0 269 Gene3D G3DSA:3.40.50.150 5 257 4.9E-38 T 29-03-2018 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 SUPERFAMILY SSF51984 10 97 2.0E-9 T 29-03-2018 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Pfam PF08245 Mur ligase middle domain 120 291 2.1E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 381 5.4E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 SUPERFAMILY SSF53244 434 480 3.57E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 SUPERFAMILY SSF53244 314 399 3.57E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 13 479 5.7E-133 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Gene3D G3DSA:3.40.1190.10 98 311 1.4E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Gene3D G3DSA:3.90.190.20 317 480 1.6E-34 T 29-03-2018 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Gene3D G3DSA:3.40.50.720 13 97 3.1E-12 T 29-03-2018 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 SUPERFAMILY SSF53623 114 310 7.85E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15100 29e1cea60c68ede79f9a2918bf01a7c9 483 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 11 481 31.287 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS14850 dfa9a583ff9bddb1ddecfe2cea443e71 363 Pfam PF02470 MlaD protein 27 101 4.2E-11 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS14850 dfa9a583ff9bddb1ddecfe2cea443e71 363 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 3 293 7.7E-49 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14850 dfa9a583ff9bddb1ddecfe2cea443e71 363 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 33 - T 29-03-2018 IPR010916 TonB box, conserved site MSG_RS13150 456326186892f77a36087c97e73cb171 162 PIRSF PIRSF002560 1 157 1.6E-62 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 86 106 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 128 149 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 44 64 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 65 85 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 107 127 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 3 22 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 PRINTS PR00601 Bacterioferritin signature 23 43 1.6E-63 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 1.7E-72 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 Gene3D G3DSA:1.20.5.420 85 138 1.8E-13 T 29-03-2018 MSG_RS13150 456326186892f77a36087c97e73cb171 162 Gene3D G3DSA:1.20.1260.10 1 77 3.1E-16 T 29-03-2018 IPR012347 Ferritin-related MSG_RS13150 456326186892f77a36087c97e73cb171 162 Pfam PF00210 Ferritin-like domain 10 143 6.2E-31 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MSG_RS13150 456326186892f77a36087c97e73cb171 162 SUPERFAMILY SSF47240 1 153 3.07E-43 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS01050 b88e0b2db456c94ab73173b67e6a72ec 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.9E-23 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS01050 b88e0b2db456c94ab73173b67e6a72ec 101 SUPERFAMILY SSF57716 2 101 5.23E-34 T 29-03-2018 MSG_RS01050 b88e0b2db456c94ab73173b67e6a72ec 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.928 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MSG_RS01050 b88e0b2db456c94ab73173b67e6a72ec 101 Gene3D G3DSA:4.10.830.10 1 101 4.9E-31 T 29-03-2018 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PRINTS PR00069 Aldo-keto reductase signature 198 222 1.3E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PRINTS PR00069 Aldo-keto reductase signature 161 190 1.3E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PRINTS PR00069 Aldo-keto reductase signature 127 144 1.3E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.3E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.3E-46 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 Pfam PF00248 Aldo/keto reductase family 24 262 1.2E-41 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 Gene3D G3DSA:3.20.20.100 3 276 2.4E-91 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 PIRSF PIRSF000097 1 280 2.2E-83 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 SUPERFAMILY SSF51430 8 265 2.23E-87 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS13680 02d8ec5938083707d857ba3546809bc1 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 Gene3D G3DSA:3.40.50.720 15 296 1.1E-102 T 29-03-2018 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 SUPERFAMILY SSF48179 298 498 1.87E-42 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 SUPERFAMILY SSF51735 18 296 7.87E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 Gene3D G3DSA:1.10.1040.10 297 502 3.0E-43 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 233 245 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 42 203 1.2E-37 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 PRINTS PR00084 Mannitol dehydrogenase signature 194 207 6.9E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 PRINTS PR00084 Mannitol dehydrogenase signature 263 278 6.9E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 PRINTS PR00084 Mannitol dehydrogenase signature 43 53 6.9E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 PRINTS PR00084 Mannitol dehydrogenase signature 233 246 6.9E-19 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20450 578ea4d9fc22742df52a5445c80c9a60 508 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 232 459 2.3E-59 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 SUPERFAMILY SSF53067 7 262 2.74E-82 T 29-03-2018 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 259 4.9E-69 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 Gene3D G3DSA:3.30.420.40 257 508 7.1E-79 T 29-03-2018 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 268 458 5.8E-65 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 PIRSF PIRSF000538 5 508 3.6E-156 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 Hamap MF_00186 Glycerol kinase [glpK]. 5 505 54.654 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 Gene3D G3DSA:3.30.420.40 2 256 5.2E-82 T 29-03-2018 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 504 1.8E-224 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 370 390 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MSG_RS23325 47dc31d4e3435424a99cbdfd4e10c2c5 508 SUPERFAMILY SSF53067 262 505 2.09E-83 T 29-03-2018 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 Pfam PF12848 ABC transporter 232 273 4.9E-8 T 29-03-2018 IPR032781 ABC-transporter extension domain MSG_RS07095 c79c595f8e240d934964a77f44755469 558 SUPERFAMILY SSF52540 348 547 5.85E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07095 c79c595f8e240d934964a77f44755469 558 SUPERFAMILY SSF52540 129 235 3.84E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07095 c79c595f8e240d934964a77f44755469 558 SUPERFAMILY SSF52540 2 92 3.84E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07095 c79c595f8e240d934964a77f44755469 558 Pfam PF00005 ABC transporter 366 501 7.1E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 Pfam PF00005 ABC transporter 17 188 4.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 Gene3D G3DSA:3.40.50.300 336 557 4.4E-46 T 29-03-2018 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 Gene3D G3DSA:3.40.50.300 1 271 5.2E-50 T 29-03-2018 MSG_RS07095 c79c595f8e240d934964a77f44755469 558 SMART SM00382 26 240 9.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS07095 c79c595f8e240d934964a77f44755469 558 SMART SM00382 375 544 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Gene3D G3DSA:2.40.110.10 121 218 3.5E-32 T 29-03-2018 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Gene3D G3DSA:1.10.540.10 1 120 7.3E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Gene3D G3DSA:1.20.140.10 219 381 9.2E-37 T 29-03-2018 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 SUPERFAMILY SSF56645 3 242 1.16E-65 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 SUPERFAMILY SSF47203 231 376 2.42E-20 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 374 4.1E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 119 4.4E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22575 6d4d5794d821d99704e48fd43a719433 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 218 3.3E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 Gene3D G3DSA:1.10.10.10 115 200 5.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 Gene3D G3DSA:3.30.160.70 22 114 6.0E-22 T 29-03-2018 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 119 197 9.3E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 SUPERFAMILY SSF53155 36 113 2.35E-15 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 119 198 4.9E-25 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 168 174 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 37 108 4.2E-5 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MSG_RS13810 1eec942859fb6841a479fd2bdd115f98 200 SUPERFAMILY SSF46767 119 198 1.7E-23 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS12875 295491b5b723b68a2f6867bbdcb454a9 103 Pfam PF02406 MmoB/DmpM family 10 98 9.6E-21 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 MSG_RS12875 295491b5b723b68a2f6867bbdcb454a9 103 SUPERFAMILY SSF56029 7 100 2.22E-19 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 MSG_RS12875 295491b5b723b68a2f6867bbdcb454a9 103 Gene3D G3DSA:3.90.56.10 6 100 1.2E-22 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 MSG_RS12875 295491b5b723b68a2f6867bbdcb454a9 103 ProDom PD004249 MONOOXYGENASE COMPONENT HYDROXYLASE MMOB/DMPM PHENOL SUBUNIT 3D-STRUCTURE HYDROCARBONS IRON PHENOLHYDROXYLASE 21 102 2.0E-25 T 29-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 SUPERFAMILY SSF47336 636 716 3.53E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Pfam PF00501 AMP-binding enzyme 68 498 3.7E-55 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Pfam PF00550 Phosphopantetheine attachment site 641 707 7.1E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:3.40.50.980 26 237 1.8E-29 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:2.30.38.10 410 492 2.0E-10 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 SUPERFAMILY SSF56801 27 615 1.96E-80 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:3.30.300.30 493 617 1.9E-12 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:3.40.50.720 758 1126 3.4E-25 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:1.10.1200.10 618 711 3.9E-12 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 ProSitePatterns PS00455 Putative AMP-binding domain signature. 235 246 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Gene3D G3DSA:3.40.50.980 238 409 2.6E-27 T 29-03-2018 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 762 1161 3.3E-83 T 29-03-2018 IPR010080 Thioester reductase-like domain MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 Pfam PF07993 Male sterility protein 765 1026 4.0E-48 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MSG_RS01190 6914b3eb3f342c17c34060a872117df1 1162 SUPERFAMILY SSF51735 762 1068 3.7E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01505 da58f2dd712ac12aedc803d16014c447 315 SUPERFAMILY SSF53335 27 307 1.66E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01505 da58f2dd712ac12aedc803d16014c447 315 Gene3D G3DSA:3.40.50.150 7 288 2.2E-58 T 29-03-2018 MSG_RS01505 da58f2dd712ac12aedc803d16014c447 315 Pfam PF04072 Leucine carboxyl methyltransferase 31 213 6.9E-62 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS01505 da58f2dd712ac12aedc803d16014c447 315 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 29 290 2.5E-87 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 SUPERFAMILY SSF90123 13 314 8.89E-27 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 Pfam PF00005 ABC transporter 357 506 4.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 Gene3D G3DSA:3.40.50.300 325 582 4.2E-69 T 29-03-2018 MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 SMART SM00382 366 552 1.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 Gene3D G3DSA:1.20.1560.10 1 315 7.8E-19 T 29-03-2018 MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 SUPERFAMILY SSF52540 338 576 8.7E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18030 b172cc1c4c59d0283b7c83a72c48e31f 587 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 SMART SM00646 255 370 3.8E-35 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Gene3D G3DSA:1.10.101.10 1 93 1.4E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 SUPERFAMILY SSF53187 190 373 6.91E-39 T 29-03-2018 MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Gene3D G3DSA:3.40.630.40 188 379 4.9E-40 T 29-03-2018 MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Pfam PF01471 Putative peptidoglycan binding domain 105 160 4.4E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Pfam PF01471 Putative peptidoglycan binding domain 18 83 7.6E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Gene3D G3DSA:1.10.101.10 98 161 1.2E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 193 370 1.6E-30 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 SUPERFAMILY SSF47090 102 161 7.06E-18 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS24670 07cdf2f8fe3991972df156adc7ffa54e 406 SUPERFAMILY SSF47090 10 83 6.02E-12 T 29-03-2018 IPR002477 Peptidoglycan binding-like MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 485 2.0E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS02025 7f76224957340ebe55408232e189f75b 500 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Gene3D G3DSA:3.30.300.30 395 498 3.8E-29 T 29-03-2018 MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Pfam PF00501 AMP-binding enzyme 9 401 2.4E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Gene3D G3DSA:3.40.50.980 153 309 1.6E-40 T 29-03-2018 MSG_RS02025 7f76224957340ebe55408232e189f75b 500 SUPERFAMILY SSF56801 6 497 3.4E-122 T 29-03-2018 MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Gene3D G3DSA:2.30.38.10 310 394 7.1E-18 T 29-03-2018 MSG_RS02025 7f76224957340ebe55408232e189f75b 500 Gene3D G3DSA:3.40.50.980 2 152 1.0E-24 T 29-03-2018 MSG_RS01445 58aa0b35ffad75f572ac4171f40f2dda 207 SUPERFAMILY SSF46689 20 95 3.59E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01445 58aa0b35ffad75f572ac4171f40f2dda 207 Gene3D G3DSA:1.10.357.10 92 202 3.5E-5 T 29-03-2018 MSG_RS01445 58aa0b35ffad75f572ac4171f40f2dda 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01445 58aa0b35ffad75f572ac4171f40f2dda 207 Gene3D G3DSA:1.10.10.60 61 91 8.3E-10 T 29-03-2018 MSG_RS01445 58aa0b35ffad75f572ac4171f40f2dda 207 Gene3D G3DSA:1.10.10.60 2 60 8.4E-11 T 29-03-2018 MSG_RS00465 81fcd32c7e6a790f94bdca216b805200 356 Gene3D G3DSA:3.30.70.270 188 355 4.5E-42 T 29-03-2018 MSG_RS00465 81fcd32c7e6a790f94bdca216b805200 356 SMART SM00267 182 353 3.9E-39 T 29-03-2018 IPR000160 GGDEF domain MSG_RS00465 81fcd32c7e6a790f94bdca216b805200 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 192 350 9.0E-33 T 29-03-2018 IPR000160 GGDEF domain MSG_RS00465 81fcd32c7e6a790f94bdca216b805200 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 349 1.8E-32 T 29-03-2018 IPR000160 GGDEF domain MSG_RS00465 81fcd32c7e6a790f94bdca216b805200 356 SUPERFAMILY SSF55073 198 351 1.65E-36 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 SUPERFAMILY SSF141868 227 440 9.42E-51 T 29-03-2018 IPR001633 EAL domain MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 Pfam PF13185 GAF domain 43 178 3.5E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 Gene3D G3DSA:3.20.20.450 212 446 2.7E-54 T 29-03-2018 IPR001633 EAL domain MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 SUPERFAMILY SSF55781 29 178 2.18E-20 T 29-03-2018 IPR029016 GAF domain-like MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 SMART SM00052 214 441 1.0E-27 T 29-03-2018 IPR001633 EAL domain MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 Gene3D G3DSA:3.30.450.40 27 184 8.7E-23 T 29-03-2018 IPR029016 GAF domain-like MSG_RS20155 950dcc7645d585b3892f33ba31cfb172 457 Pfam PF00563 EAL domain 227 436 4.7E-46 T 29-03-2018 IPR001633 EAL domain MSG_RS01200 d5776cef0d8281f3a5818925c2b6add7 217 Gene3D G3DSA:3.40.50.850 11 217 4.1E-43 T 29-03-2018 MSG_RS01200 d5776cef0d8281f3a5818925c2b6add7 217 SUPERFAMILY SSF52499 7 216 3.66E-38 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS01200 d5776cef0d8281f3a5818925c2b6add7 217 Pfam PF00857 Isochorismatase family 16 193 5.0E-25 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 Gene3D G3DSA:1.10.10.60 7 82 2.8E-20 T 29-03-2018 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 1.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 Gene3D G3DSA:1.10.357.10 83 218 1.1E-18 T 29-03-2018 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 SUPERFAMILY SSF48498 107 215 1.07E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 82 6.0E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 SUPERFAMILY SSF46689 24 102 4.14E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19870 a46b9d034c505c79b96e4e7df95e5381 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 50 80 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS01785 0fd88b7e3eda97e0ae26417b1e06305e 482 Gene3D G3DSA:3.40.1710.10 51 229 4.3E-22 T 29-03-2018 MSG_RS01785 0fd88b7e3eda97e0ae26417b1e06305e 482 Pfam PF12051 Protein of unknown function (DUF3533) 34 403 1.2E-42 T 29-03-2018 IPR022703 Domain of unknown function DUF3533 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 Gene3D G3DSA:3.50.50.60 161 531 2.4E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 Gene3D G3DSA:3.50.50.60 2 160 5.8E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.1E-8 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 3.1E-8 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.1E-8 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 SUPERFAMILY SSF51905 314 530 3.33E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 6.2E-5 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.2E-5 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 SUPERFAMILY SSF51905 146 377 9.07E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 206 1.4E-12 T 29-03-2018 MSG_RS12330 1c01edf10d4333b916694206f115d08e 533 SUPERFAMILY SSF51905 1 225 6.11E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14740 0312ef8605faa10f37fe8af060eaf787 452 PIRSF PIRSF018077 1 452 1.1E-186 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MSG_RS14740 0312ef8605faa10f37fe8af060eaf787 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 2.2E-240 T 29-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MSG_RS14740 0312ef8605faa10f37fe8af060eaf787 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.286 T 29-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MSG_RS14740 0312ef8605faa10f37fe8af060eaf787 452 Pfam PF03136 Pup-ligase protein 4 422 2.1E-159 T 29-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MSG_RS22690 4586642c89b51faa4991362f9c3d8974 305 SUPERFAMILY SSF56281 29 268 4.76E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS22690 4586642c89b51faa4991362f9c3d8974 305 Gene3D G3DSA:3.60.15.10 11 285 1.0E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Gene3D G3DSA:1.20.140.10 216 385 9.6E-56 T 29-03-2018 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 200 1.3E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 SUPERFAMILY SSF47203 223 379 1.56E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 2.8E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 SUPERFAMILY SSF56645 1 231 1.7E-51 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 PIRSF PIRSF016578 2 86 3.7E-4 T 29-03-2018 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 PIRSF PIRSF016578 231 376 8.0E-14 T 29-03-2018 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 PIRSF PIRSF016578 121 221 1.2E-5 T 29-03-2018 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 376 2.2E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Gene3D G3DSA:1.10.540.10 1 121 2.1E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10060 4a482755cffcafc8798602d6c2fd1485 389 Gene3D G3DSA:2.40.110.10 122 215 1.9E-29 T 29-03-2018 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.7E-8 T 29-03-2018 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 2.7E-8 T 29-03-2018 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 PIRSF PIRSF000171 1 596 4.2E-35 T 29-03-2018 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 SUPERFAMILY SSF46977 481 634 3.14E-41 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 Gene3D G3DSA:1.20.58.100 466 574 8.5E-29 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 SUPERFAMILY SSF56425 243 389 3.29E-32 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 SUPERFAMILY SSF51905 4 270 6.49E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 SUPERFAMILY SSF51905 393 460 6.49E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 Gene3D G3DSA:3.50.50.60 2 465 2.9E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 Pfam PF00890 FAD binding domain 10 429 7.7E-88 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02200 1a1439d47cb5b25d3df85182fac70cd3 638 Pfam PF02910 Fumarate reductase flavoprotein C-term 490 586 3.9E-23 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12425 350c9118835e1a828fee6cfb40e9810f 307 SUPERFAMILY SSF51735 7 241 3.33E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12425 350c9118835e1a828fee6cfb40e9810f 307 Gene3D G3DSA:3.40.50.720 3 300 3.3E-22 T 29-03-2018 MSG_RS12425 350c9118835e1a828fee6cfb40e9810f 307 Pfam PF13460 NAD(P)H-binding 11 190 1.6E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 PIRSF PIRSF004681 1 133 3.8E-33 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 132 9.2E-23 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 94 112 - T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 SUPERFAMILY SSF111038 3 132 3.27E-32 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 128 4.0E-25 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS09875 fe6a5d998ff75e8d1e49b2537a674b0a 133 Gene3D G3DSA:2.60.120.460 1 133 1.2E-31 T 29-03-2018 IPR001602 Uncharacterised protein family UPF0047 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 5 75 2.0E-14 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 18.933 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 9.0E-22 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 SUPERFAMILY SSF82697 3 75 3.14E-22 T 29-03-2018 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 Gene3D G3DSA:3.30.1280.10 3 77 1.5E-24 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21910 82811ed11310ee3d60cd61cdb26679da 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 6.3E-24 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 SMART SM00347 22 124 8.9E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 Gene3D G3DSA:1.20.5.420 3 29 3.1E-5 T 29-03-2018 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 SUPERFAMILY SSF46785 7 137 2.84E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 Pfam PF12802 MarR family 32 87 9.6E-11 T 29-03-2018 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 Gene3D G3DSA:1.10.10.10 30 101 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.8E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.8E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.8E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS11915 f22880ec34a751bc23c754cc368ce85a 155 Gene3D G3DSA:1.10.287.100 102 139 2.5E-11 T 29-03-2018 MSG_RS13500 fc2ccc8e26f724f18f04841315f22a4c 300 SUPERFAMILY SSF51735 2 290 3.15E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13500 fc2ccc8e26f724f18f04841315f22a4c 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 219 5.0E-15 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS13500 fc2ccc8e26f724f18f04841315f22a4c 300 Gene3D G3DSA:3.40.50.720 2 296 9.4E-30 T 29-03-2018 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 8.7E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 SUPERFAMILY SSF46689 7 71 6.16E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 Gene3D G3DSA:1.10.357.10 65 204 4.1E-12 T 29-03-2018 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 Gene3D G3DSA:1.10.10.60 7 64 1.6E-22 T 29-03-2018 MSG_RS06800 4fefa827bb42a0b9cb4e42bef082c040 207 SUPERFAMILY SSF48498 84 202 6.67E-30 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS06525 c201a2ddec80a5b6e859a0ec6d7a38e1 77 SUPERFAMILY SSF69047 8 62 1.83E-5 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS06525 c201a2ddec80a5b6e859a0ec6d7a38e1 77 Gene3D G3DSA:1.10.1470.10 7 76 1.5E-9 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 287 434 1.0E-9 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 SUPERFAMILY SSF55073 285 440 8.79E-37 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 Gene3D G3DSA:3.40.50.1820 8 278 2.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 SUPERFAMILY SSF53474 7 271 8.69E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 Gene3D G3DSA:3.30.70.1230 282 441 2.0E-28 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 SMART SM00044 246 423 7.1E-4 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 Pfam PF12146 Serine aminopeptidase, S33 61 262 3.1E-13 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 8.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 8.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 8.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02570 ff1b1119ca6c8b42848e705dc100b16d 441 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 8.6E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 71 85 2.6E-23 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 2.6E-23 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 159 2.6E-23 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 193 202 2.6E-23 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 105 123 2.6E-23 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 SUPERFAMILY SSF52096 11 221 6.0E-52 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 Pfam PF01039 Carboxyl transferase domain 15 477 3.2E-75 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 SUPERFAMILY SSF52096 239 488 1.39E-45 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 Gene3D G3DSA:3.90.226.10 4 232 1.3E-42 T 29-03-2018 MSG_RS20640 007783d2d95779049ad42a9efd95d57c 490 Gene3D G3DSA:3.90.226.10 239 464 7.3E-33 T 29-03-2018 MSG_RS21820 f6181520e5123aacbbc431bd6a23b18d 115 SUPERFAMILY SSF54593 1 113 1.55E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS21820 f6181520e5123aacbbc431bd6a23b18d 115 Gene3D G3DSA:3.10.180.10 1 115 8.2E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 SMART SM01230 101 356 2.2E-98 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 Gene3D G3DSA:3.10.20.70 1 100 1.8E-17 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 SUPERFAMILY SSF55931 101 440 7.16E-91 T 29-03-2018 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 Pfam PF00120 Glutamine synthetase, catalytic domain 103 439 8.3E-88 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 SUPERFAMILY SSF54368 4 100 5.62E-19 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 Gene3D G3DSA:3.30.590.10 101 443 5.5E-95 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS10005 818f6d83437d4f2a79cc32723365aaef 443 TIGRFAM TIGR03105 gln_synth_III: glutamine synthetase, type III 9 440 2.5E-175 T 29-03-2018 IPR017536 Glutamine synthetase, type III MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 Gene3D G3DSA:3.40.50.720 5 101 4.1E-6 T 29-03-2018 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 Gene3D G3DSA:3.90.660.10 226 395 1.2E-28 T 29-03-2018 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 Gene3D G3DSA:1.10.405.10 108 196 1.3E-21 T 29-03-2018 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 Pfam PF01593 Flavin containing amine oxidoreductase 13 446 2.5E-64 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 SUPERFAMILY SSF54373 290 393 3.86E-22 T 29-03-2018 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 293 312 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 91 113 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 397 419 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 173 194 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 376 395 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 428 445 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 PRINTS PR00757 Flavin-containing amine oxidase signature 5 24 1.1E-29 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 SUPERFAMILY SSF51905 2 308 8.2E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19335 978136ec79950b1d0cf1a9aa4ba023c0 455 SUPERFAMILY SSF51905 410 446 8.2E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13600 a1299864818bcddcda48ab9f45693476 251 Pfam PF08924 Domain of unknown function (DUF1906) 46 172 1.6E-26 T 29-03-2018 IPR015020 Protein of unknown function DUF1906 MSG_RS13600 a1299864818bcddcda48ab9f45693476 251 SUPERFAMILY SSF51445 50 182 2.06E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS13600 a1299864818bcddcda48ab9f45693476 251 Gene3D G3DSA:3.20.20.80 38 221 2.2E-18 T 29-03-2018 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 Gene3D G3DSA:2.60.120.200 593 762 1.9E-9 T 29-03-2018 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 Gene3D G3DSA:3.30.1120.10 491 581 1.5E-11 T 29-03-2018 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 SUPERFAMILY SSF53649 33 571 6.4E-127 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 Gene3D G3DSA:3.40.720.10 30 490 3.4E-95 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 Pfam PF00884 Sulfatase 33 462 7.8E-95 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 ProSitePatterns PS00149 Sulfatases signature 2. 129 139 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS04510 49144f8bf585631eb1caf21857a37f50 783 ProSitePatterns PS00523 Sulfatases signature 1. 77 89 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF56784 339 392 9.18E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF56784 280 305 9.18E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF56784 427 571 9.18E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF81665 576 781 5.1E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF81665 2 95 5.1E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF81665 193 287 5.1E-59 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 Gene3D G3DSA:2.70.150.10 1 191 6.1E-27 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 Gene3D G3DSA:3.40.1110.10 254 447 4.7E-18 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 SUPERFAMILY SSF81653 98 188 2.62E-20 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 Gene3D G3DSA:1.20.1110.10 452 781 7.8E-46 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 295 301 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 Pfam PF00122 E1-E2 ATPase 96 271 1.0E-40 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 502 604 1.2E-25 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 67 310 3.6E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 451 461 5.4E-23 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 550 562 5.4E-23 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 5.4E-23 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 142 156 5.4E-23 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 546 5.4E-23 T 29-03-2018 MSG_RS20620 1d7fc1512ad75312dbce2aace18d6d59 797 Pfam PF00702 haloacid dehalogenase-like hydrolase 289 541 1.3E-19 T 29-03-2018 MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 122 484 1.6E-48 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 PIRSF PIRSF002741 22 559 1.1E-52 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 Gene3D G3DSA:3.10.105.10 327 533 3.9E-46 T 29-03-2018 MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 Gene3D G3DSA:3.90.76.10 84 191 1.8E-12 T 29-03-2018 MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 SUPERFAMILY SSF53850 61 561 3.8E-83 T 29-03-2018 MSG_RS18505 67c76459b3d5341519e7099934d0827d 564 Gene3D G3DSA:3.40.190.10 192 326 3.2E-26 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 1052 1058 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF81665 768 828 5.1E-50 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF81665 1382 1591 5.1E-50 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF81665 951 1044 5.1E-50 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 853 1075 1.6E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1293 1413 7.7E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Gene3D G3DSA:1.20.1110.10 1359 1601 1.5E-31 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Pfam PF00689 Cation transporting ATPase, C-terminus 1479 1587 4.3E-9 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF81653 854 950 5.36E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Pfam PF00702 haloacid dehalogenase-like hydrolase 1046 1346 1.2E-24 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1050 1064 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1254 1264 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1332 1351 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1232 1243 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 891 905 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1356 1368 3.4E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Gene3D G3DSA:3.40.1110.10 1000 1230 1.8E-38 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Gene3D G3DSA:3.40.50.1000 1231 1358 1.2E-22 T 29-03-2018 IPR023214 HAD-like domain MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1364 1389 5.5E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1184 1202 5.5E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1304 1320 5.5E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1332 1348 5.5E-17 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Gene3D G3DSA:2.70.150.10 778 953 1.5E-27 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 Pfam PF00122 E1-E2 ATPase 851 1028 5.1E-38 T 29-03-2018 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF81660 1080 1238 1.18E-21 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF56784 1048 1068 2.34E-43 T 29-03-2018 IPR023214 HAD-like domain MSG_RS01070 2cba26f47a7c2e2f5481288cbb348d19 1609 SUPERFAMILY SSF56784 1181 1438 2.34E-43 T 29-03-2018 IPR023214 HAD-like domain MSG_RS22410 a7427e834d67530bbeed9170ea5d146b 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 6.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS22410 a7427e834d67530bbeed9170ea5d146b 174 SUPERFAMILY SSF51161 1 155 1.37E-37 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS22410 a7427e834d67530bbeed9170ea5d146b 174 Gene3D G3DSA:2.160.10.10 2 168 4.6E-32 T 29-03-2018 MSG_RS18090 c7a05073e163a3555a00450cac50d685 344 Gene3D G3DSA:3.60.70.12 1 341 1.2E-106 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS18090 c7a05073e163a3555a00450cac50d685 344 SUPERFAMILY SSF56266 2 339 4.97E-78 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS18090 c7a05073e163a3555a00450cac50d685 344 Pfam PF03576 Peptidase family S58 2 330 9.3E-72 T 29-03-2018 IPR005321 Peptidase S58, DmpA MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 SMART SM00898 2 109 6.0E-17 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 SUPERFAMILY SSF46946 122 187 2.94E-18 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 84 3.5E-10 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 SMART SM01232 123 211 2.2E-18 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 185 1.0E-9 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 SUPERFAMILY SSF57716 215 254 1.97E-11 T 29-03-2018 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 Gene3D G3DSA:3.20.190.10 1 117 8.6E-24 T 29-03-2018 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 Gene3D G3DSA:1.10.8.50 118 255 3.6E-47 T 29-03-2018 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 ProSitePatterns PS01242 Zinc finger FPG-type signature. 230 254 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 Pfam PF06827 Zinc finger found in FPG and IleRS 227 254 4.5E-6 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MSG_RS05640 d3c9497a2b6931a48ada6e2c560c18dc 255 SUPERFAMILY SSF81624 2 124 3.14E-23 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 SUPERFAMILY SSF56024 549 727 2.24E-62 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Gene3D G3DSA:1.20.58.310 51 153 1.3E-36 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Gene3D G3DSA:3.30.870.10 363 548 8.2E-21 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 SUPERFAMILY SSF56024 371 545 2.26E-57 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Hamap MF_00347 Polyphosphate kinase [ppk]. 47 728 29.406 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 48 724 2.5E-246 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Pfam PF13090 Polyphosphate kinase C-terminal domain 378 723 6.8E-149 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 SUPERFAMILY SSF140356 46 150 3.01E-36 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 PIRSF PIRSF015589 30 729 2.9E-271 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Pfam PF13089 Polyphosphate kinase N-terminal domain 49 155 9.3E-36 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 SUPERFAMILY SSF143724 152 357 4.71E-66 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Gene3D G3DSA:3.30.870.10 549 729 4.5E-39 T 29-03-2018 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Gene3D G3DSA:3.30.1840.10 154 352 5.4E-74 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MSG_RS07850 2941b52ae908c6ae46e5191b97921049 729 Pfam PF02503 Polyphosphate kinase middle domain 164 367 3.6E-69 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 Pfam PF01680 SOR/SNZ family 16 221 1.4E-105 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 SUPERFAMILY SSF51366 27 276 2.59E-59 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 ProSitePatterns PS01235 PdxS/SNZ family signature. 214 232 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 53.401 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 PIRSF PIRSF029271 4 303 1.3E-148 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 Gene3D G3DSA:3.20.20.70 27 280 6.8E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS09615 15a474119e058b99da1c787c6a6f37cd 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 2.3E-142 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS24225 a85400c11cca538536a28ab240c52caf 271 Gene3D G3DSA:3.40.50.1000 2 271 9.0E-42 T 29-03-2018 IPR023214 HAD-like domain MSG_RS24225 a85400c11cca538536a28ab240c52caf 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 264 1.5E-60 T 29-03-2018 IPR023214 HAD-like domain MSG_RS24225 a85400c11cca538536a28ab240c52caf 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 264 4.7E-49 T 29-03-2018 IPR000150 Cof family GO:0016787 MSG_RS24225 a85400c11cca538536a28ab240c52caf 271 SUPERFAMILY SSF56784 4 267 2.03E-64 T 29-03-2018 IPR023214 HAD-like domain MSG_RS24225 a85400c11cca538536a28ab240c52caf 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 237 1.0E-23 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MSG_RS13535 5d5ac761e57b238103c3070eb5e330f6 279 Gene3D G3DSA:3.40.50.150 1 206 1.9E-32 T 29-03-2018 MSG_RS13535 5d5ac761e57b238103c3070eb5e330f6 279 SUPERFAMILY SSF53335 9 253 9.97E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS13535 5d5ac761e57b238103c3070eb5e330f6 279 Pfam PF04072 Leucine carboxyl methyltransferase 15 176 9.8E-30 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS13535 5d5ac761e57b238103c3070eb5e330f6 279 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 247 9.4E-37 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 Gene3D G3DSA:1.10.10.60 2 62 2.4E-15 T 29-03-2018 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 SUPERFAMILY SSF48498 84 205 4.96E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 Pfam PF13305 WHG domain 87 185 7.1E-12 T 29-03-2018 IPR025996 WHG domain MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 4.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 SUPERFAMILY SSF46689 8 73 2.05E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 Gene3D G3DSA:1.10.357.10 63 211 3.2E-24 T 29-03-2018 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04190 3a68e6ee61fa8ea09fc029fcd69d9e3c 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 Pfam PF01966 HD domain 76 220 1.5E-20 T 29-03-2018 IPR006674 HD domain MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 Gene3D G3DSA:1.10.3210.10 8 212 3.4E-60 T 29-03-2018 MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 Pfam PF13286 Phosphohydrolase-associated domain 330 417 1.9E-15 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 Gene3D G3DSA:1.10.3410.10 213 350 9.7E-26 T 29-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 SMART SM00471 72 231 1.2E-15 T 29-03-2018 IPR003607 HD/PDEase domain MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 SUPERFAMILY SSF109604 38 242 8.64E-57 T 29-03-2018 MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 7 423 31.265 T 29-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 MSG_RS16635 f390f4cf37d9d71b1f2d19bc2a70d983 424 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 411 4.9E-72 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 MSG_RS09270 082cbf58da2c205bb1ca2972b87d22f9 585 Pfam PF06259 Alpha/beta hydrolase 317 484 8.4E-30 T 29-03-2018 IPR010427 Protein of unknown function DUF1023 MSG_RS09270 082cbf58da2c205bb1ca2972b87d22f9 585 Gene3D G3DSA:3.40.50.1820 317 543 9.7E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02000 e67c87c0390106df18f9feca37222c2c 125 Pfam PF00355 Rieske [2Fe-2S] domain 5 78 5.8E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS02000 e67c87c0390106df18f9feca37222c2c 125 Gene3D G3DSA:2.102.10.10 2 122 1.6E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS02000 e67c87c0390106df18f9feca37222c2c 125 SUPERFAMILY SSF50022 2 102 1.44E-27 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF13193 AMP-binding enzyme C-terminal domain 2373 2444 5.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF13193 AMP-binding enzyme C-terminal domain 868 939 2.5E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.300.30 855 966 2.5E-36 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.300.30 2360 2473 1.8E-35 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:1.10.1200.10 967 1025 6.1E-18 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:1.10.1200.10 2474 2536 9.9E-19 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF56801 431 976 2.09E-146 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SMART SM00823 Phosphopantetheine attachment site 2470 2538 0.032 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SMART SM00823 Phosphopantetheine attachment site 963 1031 0.054 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 1225 1479 2.89E-25 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 3191 3424 6.89E-53 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF56801 1921 2483 3.79E-144 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.40.50.980 620 766 2.2E-29 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.40.50.980 2110 2273 4.4E-35 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 1506 1704 6.67E-42 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 205 440 6.78E-27 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 1690 1926 1.22E-54 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.559.10 2537 2730 5.6E-14 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.559.10 1026 1224 1.7E-16 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2104 2115 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2494 2509 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 884 4.3E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1986 2389 3.1E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF47336 2462 2534 4.84E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00668 Condensation domain 1509 1942 6.0E-85 T 29-03-2018 IPR001242 Condensation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00668 Condensation domain 1058 1478 3.5E-27 T 29-03-2018 IPR001242 Condensation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00668 Condensation domain 2566 2873 2.3E-29 T 29-03-2018 IPR001242 Condensation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00668 Condensation domain 25 350 1.3E-34 T 29-03-2018 IPR001242 Condensation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00668 Condensation domain 3013 3424 1.3E-78 T 29-03-2018 IPR001242 Condensation domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 3010 3205 7.23E-42 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 1039 1206 2.22E-25 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.559.10 22 225 2.4E-17 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF47336 955 1025 1.44E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2850 3005 1.2E-31 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1347 1502 4.4E-34 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00550 Phosphopantetheine attachment site 966 1025 4.6E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00550 Phosphopantetheine attachment site 2473 2532 5.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 2548 2709 6.11E-22 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00501 AMP-binding enzyme 476 860 6.7E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Pfam PF00501 AMP-binding enzyme 1966 2365 5.6E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:2.30.38.10 772 853 2.0E-22 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:2.30.38.10 2277 2358 1.7E-20 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.559.10 1488 1698 2.8E-40 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.30.559.10 2993 3201 4.2E-40 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 26 199 3.56E-27 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 ProSitePatterns PS00012 Phosphopantetheine attachment site. 987 1002 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 SUPERFAMILY SSF52777 2724 2979 2.56E-26 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.40.50.980 1956 2109 3.2E-45 T 29-03-2018 MSG_RS10905 0a1e53902050d4c43f2c8828c7b174f9 3426 Gene3D G3DSA:3.40.50.980 466 619 1.4E-44 T 29-03-2018 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 PRINTS PR00340 P-II protein signature 2 17 7.8E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 PRINTS PR00340 P-II protein signature 52 75 7.8E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 PRINTS PR00340 P-II protein signature 23 41 7.8E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 PRINTS PR00340 P-II protein signature 83 103 7.8E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.5E-42 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 SUPERFAMILY SSF54913 1 112 8.9E-45 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 PIRSF PIRSF039144 1 112 1.9E-54 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 Gene3D G3DSA:3.30.70.120 1 109 5.9E-48 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS08130 bcda416e98648bd18ebbf2b6b81970d5 112 SMART SM00938 4 105 9.7E-62 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MSG_RS07595 26acc070186a083e09cc789e263dfd62 508 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 13 499 1.6E-156 T 29-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 MSG_RS07595 26acc070186a083e09cc789e263dfd62 508 SUPERFAMILY SSF51905 12 319 6.29E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07595 26acc070186a083e09cc789e263dfd62 508 SUPERFAMILY SSF51905 452 491 6.29E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07595 26acc070186a083e09cc789e263dfd62 508 Pfam PF01593 Flavin containing amine oxidoreductase 20 491 1.4E-40 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS07595 26acc070186a083e09cc789e263dfd62 508 Gene3D G3DSA:3.50.50.60 3 493 8.2E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 SUPERFAMILY SSF48256 8 367 4.58E-119 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 Pfam PF00285 Citrate synthase, C-terminal domain 11 357 2.1E-115 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 368 2.3E-138 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 Gene3D G3DSA:1.10.580.10 16 264 5.9E-87 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 176 191 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 198 226 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 308 324 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 127 140 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 328 342 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PRINTS PR00143 Citrate synthase signature 251 271 3.9E-36 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 PIRSF PIRSF001369 2 372 4.0E-116 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 ProSitePatterns PS00480 Citrate synthase signature. 258 270 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MSG_RS19315 37938d36cf8c9e9a00c37fea2b4b7123 372 Gene3D G3DSA:1.10.580.10 304 355 2.6E-10 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 SUPERFAMILY SSF48498 89 188 2.45E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 Gene3D G3DSA:1.10.10.60 2 46 1.3E-11 T 29-03-2018 MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 Gene3D G3DSA:1.10.260.40 47 74 2.1E-9 T 29-03-2018 MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 Gene3D G3DSA:1.10.357.10 75 202 8.8E-11 T 29-03-2018 MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 SUPERFAMILY SSF46689 9 93 1.08E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 Pfam PF13305 WHG domain 98 172 1.8E-6 T 29-03-2018 IPR025996 WHG domain MSG_RS15130 09f6b1b2a710cd29a4030eb33607bbbc 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 68 5.7E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 SUPERFAMILY SSF54631 215 355 3.41E-28 T 29-03-2018 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 SMART SM01091 354 444 3.5E-23 T 29-03-2018 IPR005170 Transporter-associated domain MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Pfam PF01595 Domain of unknown function DUF21 12 203 1.7E-35 T 29-03-2018 IPR002550 Domain of unknown function DUF21 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Gene3D G3DSA:3.10.580.10 201 349 1.1E-30 T 29-03-2018 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Pfam PF03471 Transporter associated domain 356 442 3.6E-20 T 29-03-2018 IPR005170 Transporter-associated domain MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 SUPERFAMILY SSF56176 356 448 1.55E-18 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Pfam PF00571 CBS domain 221 275 4.6E-6 T 29-03-2018 IPR000644 CBS domain MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Pfam PF00571 CBS domain 292 340 4.1E-4 T 29-03-2018 IPR000644 CBS domain MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 Gene3D G3DSA:3.30.465.10 350 445 3.3E-24 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 SMART SM00116 292 340 22.0 T 29-03-2018 IPR000644 CBS domain MSG_RS12915 94e2b557e432c0b69ae0feaf1feb21ad 456 SMART SM00116 229 278 6.7E-4 T 29-03-2018 IPR000644 CBS domain MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 Gene3D G3DSA:3.40.47.10 1 170 3.9E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 332 1.8E-124 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 332 3.5E-30 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 332 59.256 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 Gene3D G3DSA:3.40.47.10 171 334 1.2E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 1.4E-24 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS03725 310b1511e83b18037907fba6f1d92235 335 SUPERFAMILY SSF53901 7 332 5.77E-62 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 327 2.2E-30 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Gene3D G3DSA:3.40.50.970 1 185 5.7E-43 T 29-03-2018 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 SUPERFAMILY SSF52518 6 182 1.42E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Gene3D G3DSA:3.40.50.1220 188 347 4.8E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 536 8.9E-27 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 SUPERFAMILY SSF52467 189 363 1.57E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 4 554 2.8E-285 T 29-03-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 173 4.5E-45 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 Gene3D G3DSA:3.40.50.970 348 555 1.2E-38 T 29-03-2018 MSG_RS01210 a7c91c206273d9c6c91627ddb926944a 569 SUPERFAMILY SSF52518 365 545 2.75E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS23265 641728467fc2f9204d9d2e2e270f6157 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 176 1.6E-46 T 29-03-2018 IPR006286 Peptidase C56, PfpI MSG_RS23265 641728467fc2f9204d9d2e2e270f6157 184 Gene3D G3DSA:3.40.50.880 1 183 4.9E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS23265 641728467fc2f9204d9d2e2e270f6157 184 SUPERFAMILY SSF52317 7 178 1.58E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS23265 641728467fc2f9204d9d2e2e270f6157 184 Pfam PF01965 DJ-1/PfpI family 8 177 6.4E-52 T 29-03-2018 IPR002818 DJ-1/PfpI MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF52096 803 1072 1.13E-58 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:2.40.50.100 458 559 4.6E-8 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 109 5.2E-37 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:3.90.226.10 563 838 1.4E-46 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Pfam PF00364 Biotin-requiring enzyme 504 554 1.8E-5 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF52096 580 834 2.57E-50 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SMART SM00878 350 460 1.7E-38 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF51246 345 464 1.46E-28 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:3.30.1490.20 118 199 3.8E-14 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF52440 4 110 4.68E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Pfam PF01039 Carboxyl transferase domain 602 1068 1.2E-69 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:3.40.50.20 1 117 1.0E-41 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:3.30.470.20 202 457 6.1E-72 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 320 1.5E-51 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF56059 82 320 4.6E-53 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Gene3D G3DSA:3.90.226.10 839 1072 1.1E-47 T 29-03-2018 MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 SUPERFAMILY SSF51230 483 555 5.23E-10 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS08725 ad991d82e44daf929c68a8aecc160273 1075 Pfam PF02785 Biotin carboxylase C-terminal domain 350 461 1.3E-27 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS12800 f11539106cb8a3ef7db824eacaa7527e 198 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 76 4.9E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS12800 f11539106cb8a3ef7db824eacaa7527e 198 PIRSF PIRSF000847 7 194 8.5E-43 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MSG_RS12800 f11539106cb8a3ef7db824eacaa7527e 198 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 SUPERFAMILY SSF75138 205 329 2.9E-21 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Pfam PF01515 Phosphate acetyl/butaryl transferase 367 684 1.0E-130 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Pfam PF13500 AAA domain 8 202 6.3E-22 T 29-03-2018 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 383 684 1.0E-121 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 SUPERFAMILY SSF52540 8 179 1.17E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 SUPERFAMILY SSF53659 366 688 3.33E-94 T 29-03-2018 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Gene3D G3DSA:3.40.718.10 385 664 2.6E-64 T 29-03-2018 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Gene3D G3DSA:3.40.1390.20 206 344 2.2E-28 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Pfam PF07085 DRTGG domain 209 321 9.9E-24 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 Gene3D G3DSA:3.40.50.300 4 205 8.1E-27 T 29-03-2018 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 PIRSF PIRSF006107 194 692 1.8E-160 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MSG_RS02970 9b7f3ee5ea4fc9c6d295154f38c28bbd 694 PIRSF PIRSF006107 5 190 2.6E-9 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 TIGRFAM TIGR00833 actII: transport protein 26 934 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 Gene3D G3DSA:1.20.1640.10 145 365 2.3E-29 T 29-03-2018 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 Gene3D G3DSA:1.20.1640.10 719 932 1.0E-24 T 29-03-2018 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 Pfam PF03176 MMPL family 58 387 1.1E-108 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 Pfam PF03176 MMPL family 610 942 1.1E-100 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 SUPERFAMILY SSF82866 158 357 1.01E-26 T 29-03-2018 MSG_RS15625 2e0cbece495c5222618881ba74d97aa0 962 SUPERFAMILY SSF82866 725 934 2.49E-27 T 29-03-2018 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 253 447 1.1E-100 T 29-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 10 240 3.1E-80 T 29-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 15 447 55.665 T 29-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Pfam PF00881 Nitroreductase family 258 426 8.8E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Pfam PF01996 F420-0:Gamma-glutamyl ligase 18 60 4.0E-6 T 29-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Pfam PF01996 F420-0:Gamma-glutamyl ligase 86 217 2.0E-32 T 29-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 SUPERFAMILY SSF55469 254 435 7.33E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Gene3D G3DSA:3.40.109.10 252 444 1.7E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 SUPERFAMILY SSF144010 11 245 1.44E-65 T 29-03-2018 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Gene3D G3DSA:3.30.1330.100 5 118 2.1E-28 T 29-03-2018 MSG_RS05825 fd3288d5801192ab78a522229ac62396 447 Gene3D G3DSA:3.30.1330.100 119 225 1.4E-26 T 29-03-2018 MSG_RS06960 753224a236d04333805f2be48fa6f699 488 Gene3D G3DSA:3.40.710.10 28 480 3.8E-89 T 29-03-2018 MSG_RS06960 753224a236d04333805f2be48fa6f699 488 Pfam PF00144 Beta-lactamase 54 462 9.2E-62 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS06960 753224a236d04333805f2be48fa6f699 488 SUPERFAMILY SSF56601 39 258 1.64E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS06960 753224a236d04333805f2be48fa6f699 488 SUPERFAMILY SSF56601 405 467 1.64E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS06960 753224a236d04333805f2be48fa6f699 488 SUPERFAMILY SSF56601 305 372 1.64E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Pfam PF00448 SRP54-type protein, GTPase domain 100 306 3.5E-69 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 SMART SM00963 1 86 2.3E-33 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 436 2.2E-177 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Pfam PF02978 Signal peptide binding domain 338 435 2.1E-29 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 SMART SM00382 99 311 4.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS08150 04248a56fba4235302e92a7bea007578 525 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 279 292 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.7E-20 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Gene3D G3DSA:3.40.50.300 92 307 2.7E-43 T 29-03-2018 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 SUPERFAMILY SSF47446 338 438 1.8E-32 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 SMART SM00962 100 306 7.3E-108 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Gene3D G3DSA:1.10.260.30 337 439 1.6E-33 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Gene3D G3DSA:1.20.120.140 1 91 1.2E-26 T 29-03-2018 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 33.561 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MSG_RS08150 04248a56fba4235302e92a7bea007578 525 SUPERFAMILY SSF52540 42 364 1.06E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02235 c9ba3bc43a85680f00a0209d9bcfcb80 122 Gene3D G3DSA:2.102.10.10 5 118 9.1E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS02235 c9ba3bc43a85680f00a0209d9bcfcb80 122 Pfam PF13806 Rieske-like [2Fe-2S] domain 10 113 1.6E-34 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MSG_RS02235 c9ba3bc43a85680f00a0209d9bcfcb80 122 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 10 113 1.4E-27 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MSG_RS02235 c9ba3bc43a85680f00a0209d9bcfcb80 122 SUPERFAMILY SSF50022 10 115 2.62E-31 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS15305 350096f261571fd3bb2a752a70bfa9eb 398 Gene3D G3DSA:2.102.10.10 216 398 2.0E-39 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS15305 350096f261571fd3bb2a752a70bfa9eb 398 SUPERFAMILY SSF50022 307 396 8.51E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS15305 350096f261571fd3bb2a752a70bfa9eb 398 Pfam PF00355 Rieske [2Fe-2S] domain 312 369 4.3E-9 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 Gene3D G3DSA:3.40.47.10 317 544 3.4E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 Gene3D G3DSA:2.40.50.140 60 128 5.9E-11 T 29-03-2018 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 SUPERFAMILY SSF53901 170 397 2.78E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 SUPERFAMILY SSF50249 6 128 1.05E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 20 55 2.0E-8 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 Gene3D G3DSA:3.40.47.10 168 316 1.9E-4 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 SUPERFAMILY SSF53901 433 538 6.83E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21230 a732d064f5583f8ac10130df465f5286 551 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 122 3.0E-13 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 SUPERFAMILY SSF56801 17 520 4.71E-122 T 29-03-2018 MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Gene3D G3DSA:3.30.300.30 420 520 2.6E-23 T 29-03-2018 MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Gene3D G3DSA:3.40.50.980 180 335 2.3E-39 T 29-03-2018 MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Gene3D G3DSA:2.30.38.10 336 419 7.0E-20 T 29-03-2018 MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Gene3D G3DSA:3.40.50.980 15 179 4.6E-32 T 29-03-2018 MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 509 3.7E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS01215 b948177f8e0d394f793d8858d46a723b 524 Pfam PF00501 AMP-binding enzyme 24 426 2.9E-80 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS18400 bbda80da91895a255c4be2b8f14ecc79 408 Gene3D G3DSA:3.20.20.450 1 237 7.7E-44 T 29-03-2018 IPR001633 EAL domain MSG_RS18400 bbda80da91895a255c4be2b8f14ecc79 408 SUPERFAMILY SSF141868 3 231 6.02E-43 T 29-03-2018 IPR001633 EAL domain MSG_RS18400 bbda80da91895a255c4be2b8f14ecc79 408 SMART SM00052 1 232 1.3E-9 T 29-03-2018 IPR001633 EAL domain MSG_RS18400 bbda80da91895a255c4be2b8f14ecc79 408 Pfam PF00563 EAL domain 4 229 6.0E-40 T 29-03-2018 IPR001633 EAL domain MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Gene3D G3DSA:3.40.50.720 228 435 2.4E-66 T 29-03-2018 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Gene3D G3DSA:1.20.5.100 205 227 2.9E-13 T 29-03-2018 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 PIRSF PIRSF000124 1 438 7.1E-120 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 298 1.6E-30 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 SUPERFAMILY SSF48179 204 302 1.25E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 SUPERFAMILY SSF51735 1 193 1.65E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02630 29a1bab004020a9db478f49bea882981 441 PIRSF PIRSF500134 1 440 2.6E-156 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 SUPERFAMILY SSF52413 312 433 6.8E-34 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 422 3.6E-29 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Gene3D G3DSA:3.40.50.720 1 201 2.9E-54 T 29-03-2018 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 3.6E-61 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 419 7.8E-135 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MSG_RS02630 29a1bab004020a9db478f49bea882981 441 SMART SM00984 322 423 4.5E-45 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS06610 9641846fe43e4b215e3a5cf5cfc8d84d 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 141 1.7E-13 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS06610 9641846fe43e4b215e3a5cf5cfc8d84d 144 Gene3D G3DSA:3.30.530.20 1 144 1.6E-18 T 29-03-2018 IPR023393 START-like domain MSG_RS06610 9641846fe43e4b215e3a5cf5cfc8d84d 144 SUPERFAMILY SSF55961 1 140 1.14E-18 T 29-03-2018 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 Gene3D G3DSA:1.10.260.40 49 150 9.7E-14 T 29-03-2018 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 SUPERFAMILY SSF48498 88 196 1.69E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 Gene3D G3DSA:1.10.10.60 2 48 2.0E-17 T 29-03-2018 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 SUPERFAMILY SSF46689 17 85 3.01E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00790 3d5c53fd1999d41806f9efed282cf791 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 6.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 Pfam PF00557 Metallopeptidase family M24 158 360 2.9E-15 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 Gene3D G3DSA:3.40.350.10 15 134 9.9E-14 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 SUPERFAMILY SSF55920 150 372 1.31E-31 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 Gene3D G3DSA:3.90.230.10 135 373 3.5E-27 T 29-03-2018 MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 150 2.6E-12 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 MSG_RS21390 6c52654911e8853c602335050cc5a0f2 375 SUPERFAMILY SSF53092 6 148 4.88E-18 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MSG_RS16235 a68a32c172c78336fa86023236a04890 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 323 1.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SMART SM00387 365 483 2.6E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SUPERFAMILY SSF55874 313 481 4.45E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SUPERFAMILY SSF158472 186 232 3.79E-5 T 29-03-2018 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SMART SM00304 183 236 3.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 Pfam PF00672 HAMP domain 185 232 4.5E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SUPERFAMILY SSF47384 239 323 2.55E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 Gene3D G3DSA:3.30.450.20 124 282 3.6E-6 T 29-03-2018 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 2.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 2.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 2.7E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 SMART SM00388 251 323 7.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS16235 a68a32c172c78336fa86023236a04890 496 Gene3D G3DSA:3.30.565.10 283 482 5.5E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16235 a68a32c172c78336fa86023236a04890 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 482 3.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS09180 7284546bd64369f0cdbb4c1683d66b2f 140 Gene3D G3DSA:2.170.150.20 2 140 4.6E-57 T 29-03-2018 MSG_RS09180 7284546bd64369f0cdbb4c1683d66b2f 140 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 12 139 8.0E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MSG_RS09180 7284546bd64369f0cdbb4c1683d66b2f 140 Pfam PF01641 SelR domain 16 136 6.3E-52 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MSG_RS09180 7284546bd64369f0cdbb4c1683d66b2f 140 SUPERFAMILY SSF51316 10 139 5.23E-55 T 29-03-2018 IPR011057 Mss4-like MSG_RS01480 5176efbf13e3be12393d6445d24c11e5 303 Gene3D G3DSA:1.10.340.30 108 218 1.1E-18 T 29-03-2018 MSG_RS01480 5176efbf13e3be12393d6445d24c11e5 303 SUPERFAMILY SSF48150 104 282 4.54E-31 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS01480 5176efbf13e3be12393d6445d24c11e5 303 Gene3D G3DSA:1.10.1670.10 219 280 3.5E-4 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MSG_RS23685 15a016e89fe66a59f0bf641cd30a2eff 168 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 143 3.0E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS23685 15a016e89fe66a59f0bf641cd30a2eff 168 SUPERFAMILY SSF54593 11 148 1.48E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23685 15a016e89fe66a59f0bf641cd30a2eff 168 Gene3D G3DSA:3.10.180.10 10 164 1.5E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 289 4.0E-100 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 Gene3D G3DSA:1.10.10.10 72 159 2.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 SUPERFAMILY SSF88659 83 163 5.79E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 Gene3D G3DSA:3.10.450.50 160 297 1.1E-17 T 29-03-2018 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 Pfam PF04542 Sigma-70 region 2 12 73 4.1E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 SUPERFAMILY SSF88946 9 91 1.84E-7 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 Pfam PF08281 Sigma-70, region 4 106 157 2.6E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 Gene3D G3DSA:1.10.1740.10 2 71 2.5E-8 T 29-03-2018 MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 SUPERFAMILY SSF54427 170 290 4.65E-16 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS20075 6e097d940ba1633e75813d90b6dfe13e 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 159 2.8E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14205 b38ec001c572f0d96191dc47d8e3a971 168 Gene3D G3DSA:3.90.180.10 52 160 1.6E-27 T 29-03-2018 MSG_RS14205 b38ec001c572f0d96191dc47d8e3a971 168 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 84 144 9.1E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS14205 b38ec001c572f0d96191dc47d8e3a971 168 SUPERFAMILY SSF50129 59 150 4.87E-28 T 29-03-2018 IPR011032 GroES-like MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 Pfam PF00743 Flavin-binding monooxygenase-like 4 457 2.4E-45 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 SUPERFAMILY SSF51905 265 320 2.4E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 SUPERFAMILY SSF51905 348 369 2.4E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 SUPERFAMILY SSF51905 169 214 2.4E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 368 381 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 3 19 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 351 368 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 126 142 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 27 51 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 302 329 1.4E-18 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 Gene3D G3DSA:3.50.50.60 2 169 7.8E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 Gene3D G3DSA:3.50.50.60 170 434 1.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 SUPERFAMILY SSF51905 2 238 9.07E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07040 6167170ce2fd387c755ce19a7c3b50e7 496 PIRSF PIRSF000332 1 485 2.9E-51 T 29-03-2018 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 SUPERFAMILY SSF46689 5 87 6.67E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 Gene3D G3DSA:1.10.357.10 69 196 0.0018 T 29-03-2018 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 Gene3D G3DSA:1.10.260.40 40 68 3.9E-7 T 29-03-2018 MSG_RS21035 e00af968eee0ef9099d15656800e31d7 233 Gene3D G3DSA:1.10.10.60 1 39 1.3E-10 T 29-03-2018 MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 SUPERFAMILY SSF51735 11 261 3.51E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 Gene3D G3DSA:3.40.50.720 1 261 8.6E-51 T 29-03-2018 MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17965 39b27cf3f0b10ea5872c51b6d437570a 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 261 3.9E-43 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 SUPERFAMILY SSF47203 231 386 2.09E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Gene3D G3DSA:2.40.110.10 124 221 8.2E-27 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 378 3.8E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 PIRSF PIRSF016578 3 95 0.0016 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 PIRSF PIRSF016578 141 199 210.0 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 PIRSF PIRSF016578 242 387 1.2E-9 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Gene3D G3DSA:1.10.540.10 1 123 6.1E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 1.5E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Gene3D G3DSA:1.20.140.10 222 388 2.5E-49 T 29-03-2018 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 1.4E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21295 2df27a9964940340ea82ed2442e52edc 388 SUPERFAMILY SSF56645 1 246 3.14E-61 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS23525 81515e53a083168ef7896c3ab83df585 160 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 12 157 1.3E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS23525 81515e53a083168ef7896c3ab83df585 160 Gene3D G3DSA:3.30.1330.40 4 160 2.8E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS23525 81515e53a083168ef7896c3ab83df585 160 SUPERFAMILY SSF55298 11 157 2.51E-52 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS06185 f8cf4ce26da8f8da0cbbec9c1f41d143 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 17.8 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS06185 f8cf4ce26da8f8da0cbbec9c1f41d143 84 Pfam PF02467 Transcription factor WhiB 3 71 2.1E-25 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS18995 6b4dc94f19a037340c7c43dd080cce88 534 Gene3D G3DSA:1.10.10.60 430 507 3.4E-5 T 29-03-2018 MSG_RS18995 6b4dc94f19a037340c7c43dd080cce88 534 Pfam PF13556 PucR C-terminal helix-turn-helix domain 471 529 4.3E-19 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MSG_RS03630 efe44beb33ae072f4b3cb04819f9c7d3 231 SUPERFAMILY SSF52266 42 225 2.29E-25 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS03630 efe44beb33ae072f4b3cb04819f9c7d3 231 Gene3D G3DSA:3.40.50.1110 21 229 8.7E-22 T 29-03-2018 MSG_RS03630 efe44beb33ae072f4b3cb04819f9c7d3 231 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 45 215 2.4E-14 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 1.1E-40 T 29-03-2018 MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.2E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 Gene3D G3DSA:3.40.50.720 6 255 1.4E-51 T 29-03-2018 MSG_RS00870 6764469b3bfafc03c1bc2c0baedfdb97 256 SUPERFAMILY SSF51735 10 254 5.75E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 Pfam PF00582 Universal stress protein family 8 140 2.6E-26 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 SUPERFAMILY SSF52402 8 143 6.11E-29 T 29-03-2018 MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 SUPERFAMILY SSF52402 152 270 6.87E-10 T 29-03-2018 MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 Gene3D G3DSA:3.40.50.620 144 270 1.2E-7 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 PRINTS PR01438 Universal stress protein signature 100 112 2.1E-13 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 PRINTS PR01438 Universal stress protein signature 7 25 2.1E-13 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 PRINTS PR01438 Universal stress protein signature 118 140 2.1E-13 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13865 f21e31245d6aebba2b275d71ae69d0fa 270 Gene3D G3DSA:3.40.50.620 2 143 2.6E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 Pfam PF00290 Tryptophan synthase alpha chain 17 256 5.5E-69 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 55 68 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 SUPERFAMILY SSF51366 9 259 6.59E-78 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 21 262 32.518 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 Gene3D G3DSA:3.20.20.70 9 268 1.2E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11235 7b8141cb93a0d1f1bf8b5b712ce7b36c 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 16 259 2.7E-62 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 Gene3D G3DSA:3.30.70.1350 246 330 1.2E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 Pfam PF01545 Cation efflux family 55 247 3.2E-43 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 SUPERFAMILY SSF161111 50 248 8.76E-49 T 29-03-2018 MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 Pfam PF16916 Dimerisation domain of Zinc Transporter 251 327 2.7E-15 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 52 329 2.9E-70 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 Gene3D G3DSA:1.20.1510.10 51 245 5.1E-40 T 29-03-2018 MSG_RS13495 cafc3e2e611847a6bbb313e39916167f 342 SUPERFAMILY SSF160240 250 328 3.66E-16 T 29-03-2018 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 247 263 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 272 287 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 302 321 2.5E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 SMART SM01004 6 328 8.2E-206 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 SUPERFAMILY SSF51569 4 328 1.9E-126 T 29-03-2018 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 Gene3D G3DSA:3.20.20.70 1 329 5.0E-142 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 247 259 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 PIRSF PIRSF001415 1 329 1.8E-141 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS03605 005b9dd16ef269ec561cd912bd01e01b 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 327 1.6E-132 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 Gene3D G3DSA:1.10.357.10 87 216 3.5E-16 T 29-03-2018 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 Gene3D G3DSA:1.10.10.60 7 65 1.7E-10 T 29-03-2018 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 SUPERFAMILY SSF46689 23 105 3.95E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 Gene3D G3DSA:1.10.10.60 66 86 7.7E-7 T 29-03-2018 MSG_RS21360 48a2976ff74f149d190b43e552170688 216 SUPERFAMILY SSF48498 100 214 1.21E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 78 87 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 40 62 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 222 231 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 263 268 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 287 301 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00101 Aspartate carbamoyltransferase signature 138 155 4.0E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 Gene3D G3DSA:3.40.50.1370 166 308 1.8E-40 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 304 6.7E-20 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 308 39.321 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 151 2.2E-39 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 305 1.6E-85 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 8.7E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 8.7E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 294 8.7E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 8.7E-19 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 Gene3D G3DSA:3.40.50.1370 1 165 7.9E-62 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS10220 356d7d85c710c0bf7508e9803426688b 324 SUPERFAMILY SSF53671 2 306 7.86E-91 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Gene3D G3DSA:3.30.390.30 355 463 1.5E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 SUPERFAMILY SSF55424 347 463 3.61E-25 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 181 206 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 7.2E-45 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Gene3D G3DSA:3.50.50.60 2 160 6.6E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Gene3D G3DSA:3.50.50.60 281 354 5.4E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 5.6E-22 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 SUPERFAMILY SSF51905 4 338 1.69E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PIRSF PIRSF000350 2 463 1.2E-70 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Gene3D G3DSA:3.50.50.60 161 280 2.7E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 9.2E-31 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 181 199 9.2E-31 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 9.2E-31 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 9.2E-31 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 9.2E-31 T 29-03-2018 MSG_RS05585 81a1f2b333a607296f85455b2563894f 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 329 5.7E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 SUPERFAMILY SSF48498 93 206 2.67E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 Gene3D G3DSA:1.10.10.60 3 77 1.6E-15 T 29-03-2018 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 6.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 Gene3D G3DSA:1.10.357.10 78 208 1.1E-15 T 29-03-2018 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 42 73 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 201 2.4E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 SUPERFAMILY SSF46689 26 82 1.7E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15755 148852f86a3d0362898a7f401e14893e 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 SUPERFAMILY SSF53850 88 234 5.07E-18 T 29-03-2018 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 Gene3D G3DSA:3.40.190.10 173 241 4.6E-11 T 29-03-2018 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 Pfam PF03466 LysR substrate binding domain 92 232 1.8E-16 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 Gene3D G3DSA:1.10.10.10 1 87 1.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 Gene3D G3DSA:3.40.190.10 88 172 2.6E-6 T 29-03-2018 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 6.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 SUPERFAMILY SSF46785 4 108 4.83E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01810 7e20cd7d41005b37fd63f0524718ff9c 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02270 8872d903ed6260283ada1a77aff0e999 305 SMART SM00797 25 297 2.3E-102 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MSG_RS02270 8872d903ed6260283ada1a77aff0e999 305 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 288 4.3E-109 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MSG_RS02270 8872d903ed6260283ada1a77aff0e999 305 SUPERFAMILY SSF50891 175 283 9.1E-12 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS02270 8872d903ed6260283ada1a77aff0e999 305 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 283 2.8E-76 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 Gene3D G3DSA:1.10.40.30 379 449 3.1E-15 T 29-03-2018 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 SUPERFAMILY SSF48557 7 456 1.73E-80 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 SMART SM00998 365 450 6.9E-22 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 7.3E-10 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 7.3E-10 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 7.3E-10 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 Gene3D G3DSA:1.20.200.10 99 378 1.5E-54 T 29-03-2018 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 Gene3D G3DSA:1.10.275.10 5 98 2.3E-16 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 449 4.9E-13 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 Pfam PF00206 Lyase 32 296 2.1E-22 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MSG_RS21960 6a9a960840df62ceca8fbfc7e16f55d6 472 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 449 7.8E-140 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 Gene3D G3DSA:1.10.357.10 2 186 5.3E-24 T 29-03-2018 MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 SUPERFAMILY SSF48498 96 178 4.11E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18815 c6a2ba6aa56a5019f8d561a2fa94fe2f 212 SUPERFAMILY SSF46689 9 78 7.18E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 5 381 1.4E-100 T 29-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 SUPERFAMILY SSF51971 348 378 2.12E-44 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 SUPERFAMILY SSF51971 5 275 2.12E-44 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 78 8.4E-17 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 SUPERFAMILY SSF54373 256 327 1.61E-23 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 Gene3D G3DSA:3.40.50.720 3 299 1.8E-37 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 Gene3D G3DSA:3.40.50.720 300 385 2.7E-9 T 29-03-2018 MSG_RS24210 0f5f6ade21a3dde40a310b595c5182df 398 Pfam PF03275 UDP-galactopyranose mutase 153 363 6.0E-80 T 29-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 MSG_RS14410 1981459079a1c6e99a59bbf3c431aa1b 233 Gene3D G3DSA:3.40.50.1860 108 204 4.7E-12 T 29-03-2018 MSG_RS14410 1981459079a1c6e99a59bbf3c431aa1b 233 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 207 3.2E-10 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS14410 1981459079a1c6e99a59bbf3c431aa1b 233 Gene3D G3DSA:3.40.50.1860 3 107 1.2E-6 T 29-03-2018 MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 Gene3D G3DSA:3.30.450.20 280 418 3.3E-21 T 29-03-2018 MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 298 419 2.3E-9 T 29-03-2018 IPR000014 PAS domain MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 Pfam PF00990 Diguanylate cyclase, GGDEF domain 423 579 2.2E-42 T 29-03-2018 IPR000160 GGDEF domain MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 Pfam PF08447 PAS fold 323 403 7.1E-10 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 419 581 2.1E-39 T 29-03-2018 IPR000160 GGDEF domain MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 Gene3D G3DSA:3.30.70.270 419 584 5.8E-54 T 29-03-2018 MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 SUPERFAMILY SSF55785 293 406 5.32E-13 T 29-03-2018 IPR000014 PAS domain MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 SUPERFAMILY SSF55073 428 582 2.2E-41 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS06490 408b57fe2934ec1313f3723e12eb3ea2 594 SMART SM00267 412 583 2.9E-51 T 29-03-2018 IPR000160 GGDEF domain MSG_RS13990 997466cd242aeb06aa789b75e74348b9 122 Pfam PF11964 SpoIIAA-like 12 120 3.2E-14 T 29-03-2018 IPR021866 SpoIIAA-like MSG_RS13990 997466cd242aeb06aa789b75e74348b9 122 Gene3D G3DSA:3.40.50.10600 1 122 6.2E-12 T 29-03-2018 MSG_RS13990 997466cd242aeb06aa789b75e74348b9 122 SUPERFAMILY SSF52091 1 119 5.49E-27 T 29-03-2018 IPR002645 STAS domain MSG_RS03230 eafc778979b668f1777b8de12342d831 131 ProDom PD086639 PYRIDOXAMINE 5'-PHOSPHATE MB0449C OXIDASE-RELATED RV0441C/MT0457 7 111 2.0E-35 T 29-03-2018 IPR020145 Uncharacterised protein family, MT0457 MSG_RS03230 eafc778979b668f1777b8de12342d831 131 Gene3D G3DSA:2.30.110.10 1 127 2.3E-6 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS03230 eafc778979b668f1777b8de12342d831 131 SUPERFAMILY SSF50475 13 94 2.22E-5 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 30 386 3.2E-85 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 31 391 30.965 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 Gene3D G3DSA:3.40.50.2000 24 199 1.6E-33 T 29-03-2018 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 Gene3D G3DSA:3.40.50.2000 200 385 8.5E-34 T 29-03-2018 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 31 175 2.5E-38 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 221 382 1.3E-37 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MSG_RS15090 ead43941fc0d48cb4042f0c4a801a17a 412 SUPERFAMILY SSF53756 31 392 4.71E-96 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Gene3D G3DSA:2.40.40.20 722 806 1.2E-18 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 94 8.6E-19 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 105 143 5.3E-15 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SUPERFAMILY SSF53706 228 728 6.51E-76 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SMART SM00926 237 291 0.0035 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Gene3D G3DSA:2.20.25.90 237 292 2.4E-8 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SUPERFAMILY SSF50692 708 800 5.16E-9 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Gene3D G3DSA:3.40.50.740 295 455 4.3E-20 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SUPERFAMILY SSF54292 20 93 3.57E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 50 67 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Pfam PF01568 Molydopterin dinucleotide binding domain 733 790 6.5E-8 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Gene3D G3DSA:3.40.50.740 456 689 3.1E-32 T 29-03-2018 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Pfam PF00384 Molybdopterin oxidoreductase 295 434 2.3E-10 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Pfam PF00384 Molybdopterin oxidoreductase 512 641 3.0E-7 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 119 131 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 Gene3D G3DSA:3.10.20.30 16 180 1.3E-15 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 167 177 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SMART SM00929 104 144 7.8E-18 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 23 650 6.0E-168 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06735 1d01f222b9f3a008f4e8a117a26fdd38 807 SUPERFAMILY SSF54862 97 233 2.47E-30 T 29-03-2018 MSG_RS02470 e38fdad5afa0ea9bb477a8e339c98e21 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 1.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02470 e38fdad5afa0ea9bb477a8e339c98e21 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 3.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02470 e38fdad5afa0ea9bb477a8e339c98e21 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 3.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02470 e38fdad5afa0ea9bb477a8e339c98e21 206 SUPERFAMILY SSF46689 21 104 9.75E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02470 e38fdad5afa0ea9bb477a8e339c98e21 206 Gene3D G3DSA:1.10.357.10 2 206 3.0E-29 T 29-03-2018 MSG_RS05280 6666705b23815d6bd866a28f5b1bd20f 190 Pfam PF03029 Conserved hypothetical ATP binding protein 18 186 1.7E-27 T 29-03-2018 IPR004130 GPN-loop GTPase MSG_RS05280 6666705b23815d6bd866a28f5b1bd20f 190 Gene3D G3DSA:3.40.50.300 2 190 1.5E-21 T 29-03-2018 MSG_RS05280 6666705b23815d6bd866a28f5b1bd20f 190 SUPERFAMILY SSF52540 14 183 4.13E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Gene3D G3DSA:3.40.50.740 358 499 6.3E-15 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Gene3D G3DSA:3.40.50.740 65 131 3.4E-8 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 56 1.9E-9 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Gene3D G3DSA:2.40.40.20 594 733 5.0E-31 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Pfam PF01568 Molydopterin dinucleotide binding domain 608 726 1.2E-25 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 SUPERFAMILY SSF53706 11 625 2.09E-113 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 SMART SM00926 6 59 8.6E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Gene3D G3DSA:2.20.25.90 1 64 6.5E-14 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 SUPERFAMILY SSF50692 605 734 1.38E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Pfam PF00384 Molybdopterin oxidoreductase 63 482 7.1E-37 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 Gene3D G3DSA:3.40.228.10 146 357 5.9E-46 T 29-03-2018 MSG_RS12235 8832c07bf97d4abff22981ce65a5ff54 747 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 645 672 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 SMART SM00829 10 332 3.9E-48 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 SUPERFAMILY SSF51735 113 237 6.49E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 Pfam PF00107 Zinc-binding dehydrogenase 152 277 6.4E-18 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 Gene3D G3DSA:3.40.50.720 150 250 8.7E-17 T 29-03-2018 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 Gene3D G3DSA:3.90.180.10 1 149 2.7E-47 T 29-03-2018 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 SUPERFAMILY SSF50129 1 141 6.39E-37 T 29-03-2018 IPR011032 GroES-like MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 Gene3D G3DSA:3.90.180.10 251 333 0.0027 T 29-03-2018 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 1.4E-7 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS13370 1551da936564ac0d3f1a420ce839ea02 334 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MSG_RS01645 89fc9d6bc559137c43470b8b14311197 389 Pfam PF02515 CoA-transferase family III 5 376 1.0E-111 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS01645 89fc9d6bc559137c43470b8b14311197 389 Gene3D G3DSA:3.40.50.10540 1 388 1.7E-113 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS01645 89fc9d6bc559137c43470b8b14311197 389 SUPERFAMILY SSF89796 1 384 7.19E-108 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS20720 b386c716fb1caf27903fdac3838eb209 341 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 20 303 3.9E-109 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF MSG_RS20720 b386c716fb1caf27903fdac3838eb209 341 SUPERFAMILY SSF47240 35 257 1.26E-7 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS20720 b386c716fb1caf27903fdac3838eb209 341 Gene3D G3DSA:1.20.1260.10 70 302 1.9E-17 T 29-03-2018 IPR012347 Ferritin-related MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 SUPERFAMILY SSF50331 237 384 3.12E-22 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 Gene3D G3DSA:2.40.50.140 291 369 1.9E-14 T 29-03-2018 MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 Gene3D G3DSA:2.40.50.100 240 290 7.7E-11 T 29-03-2018 MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 Gene3D G3DSA:3.40.50.300 1 237 6.7E-73 T 29-03-2018 MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 SUPERFAMILY SSF52540 4 243 3.64E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 SMART SM00382 29 222 1.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18740 ffb7dd56e5c48312b0a313113c297048 392 Pfam PF00005 ABC transporter 22 162 1.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10300 1d086b33b2908913d19a997baecd2ef8 319 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 86 102 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 MSG_RS10300 1d086b33b2908913d19a997baecd2ef8 319 Gene3D G3DSA:3.40.50.1820 9 318 4.5E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10300 1d086b33b2908913d19a997baecd2ef8 319 SUPERFAMILY SSF53474 47 314 3.81E-67 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10300 1d086b33b2908913d19a997baecd2ef8 319 Pfam PF07859 alpha/beta hydrolase fold 86 293 4.1E-71 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS10300 1d086b33b2908913d19a997baecd2ef8 319 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 158 170 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 SUPERFAMILY SSF53732 1 413 4.05E-110 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 Gene3D G3DSA:3.30.499.10 268 415 8.4E-47 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 411 7.3E-121 T 29-03-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 PRINTS PR00415 Aconitase family signature 109 122 4.2E-9 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 PRINTS PR00415 Aconitase family signature 346 359 4.2E-9 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 PRINTS PR00415 Aconitase family signature 123 138 4.2E-9 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 PRINTS PR00415 Aconitase family signature 290 301 4.2E-9 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 Pfam PF00330 Aconitase family (aconitate hydratase) 79 405 8.4E-71 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 Gene3D G3DSA:3.30.499.10 1 145 1.7E-26 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS17070 8ebe195678a96add99910524e356e3f3 415 Gene3D G3DSA:3.40.1060.10 146 265 1.5E-23 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 SUPERFAMILY SSF55021 353 431 1.12E-10 T 29-03-2018 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 14 131 8.3E-22 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Gene3D G3DSA:3.30.360.10 160 305 8.8E-51 T 29-03-2018 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Pfam PF01842 ACT domain 355 425 4.3E-10 T 29-03-2018 IPR002912 ACT domain MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 SUPERFAMILY SSF55347 139 309 1.18E-49 T 29-03-2018 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 SUPERFAMILY SSF51735 5 160 1.97E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Gene3D G3DSA:3.30.70.260 351 435 3.4E-20 T 29-03-2018 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Pfam PF00742 Homoserine dehydrogenase 139 322 1.2E-65 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 PIRSF PIRSF000098 5 439 7.0E-152 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 Gene3D G3DSA:3.40.50.720 4 159 6.8E-33 T 29-03-2018 MSG_RS18330 0c72844c546e6d790b6aff362df26bb2 441 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 SUPERFAMILY SSF53178 5 189 4.45E-65 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 Gene3D G3DSA:3.40.50.1470 1 191 1.2E-71 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 2.3E-56 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 188 3.3E-58 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MSG_RS19910 6616a793758753d81b9ae90bf6a9f139 191 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 34.937 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 157 31.782 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 Pfam PF02542 YgbB family 6 155 2.1E-48 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 156 5.4E-53 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 Gene3D G3DSA:3.30.1330.50 1 158 2.5E-59 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS22725 70d7ae0b5189df687c2c4fbd45da7d0a 159 SUPERFAMILY SSF69765 5 156 7.59E-52 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MSG_RS23500 c834c7baea5245afbdc05a947f0f2056 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 242 1.3E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS23500 c834c7baea5245afbdc05a947f0f2056 246 Gene3D G3DSA:3.90.226.10 1 206 1.5E-40 T 29-03-2018 MSG_RS23500 c834c7baea5245afbdc05a947f0f2056 246 Gene3D G3DSA:1.10.12.10 207 240 0.0023 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS23500 c834c7baea5245afbdc05a947f0f2056 246 SUPERFAMILY SSF52096 7 242 4.25E-47 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 PIRSF PIRSF000706 148 240 2.2E-32 T 29-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 PIRSF PIRSF000706 2 158 1.3E-29 T 29-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 Gene3D G3DSA:3.90.1200.10 86 239 4.8E-14 T 29-03-2018 MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 Gene3D G3DSA:3.30.200.20 2 85 9.3E-19 T 29-03-2018 MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 SUPERFAMILY SSF56112 19 236 1.28E-32 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS24245 efd722a3f1b44dc6517383ce057e8c64 253 Pfam PF01636 Phosphotransferase enzyme family 141 233 8.4E-10 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS19620 119afb3587bf7c86f8e2a370ec61ef3c 290 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 4 286 3.5E-154 T 29-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 MSG_RS19620 119afb3587bf7c86f8e2a370ec61ef3c 290 Gene3D G3DSA:3.40.50.10320 1 290 6.2E-73 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS19620 119afb3587bf7c86f8e2a370ec61ef3c 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 151 5.2E-26 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MSG_RS19620 119afb3587bf7c86f8e2a370ec61ef3c 290 SUPERFAMILY SSF102588 4 288 7.06E-71 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS19620 119afb3587bf7c86f8e2a370ec61ef3c 290 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 7 287 52.31 T 29-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 7.0E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 SUPERFAMILY SSF51735 111 286 4.96E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 Gene3D G3DSA:3.40.50.720 133 305 7.0E-39 T 29-03-2018 MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 SUPERFAMILY SSF50129 1 134 5.48E-38 T 29-03-2018 IPR011032 GroES-like MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 Pfam PF00107 Zinc-binding dehydrogenase 149 259 3.7E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 Gene3D G3DSA:3.90.180.10 1 132 5.0E-40 T 29-03-2018 MSG_RS23880 6dd55d60efb747e7448ef28eed2828fc 322 SMART SM00829 10 319 2.4E-27 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 Gene3D G3DSA:3.40.50.720 57 254 3.0E-56 T 29-03-2018 MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 Gene3D G3DSA:3.40.50.720 1 56 1.6E-13 T 29-03-2018 MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 2.0E-61 T 29-03-2018 MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.6E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS08735 516ebe2d1ef525167a3597f7f1e336b5 260 SUPERFAMILY SSF51735 8 246 2.53E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 SUPERFAMILY SSF48498 86 184 1.27E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 SUPERFAMILY SSF46689 7 87 2.53E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 Gene3D G3DSA:1.10.357.10 2 192 9.3E-27 T 29-03-2018 MSG_RS14525 0d389a0e3a3a2148f6b2517d604451c9 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 5.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 4.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 45 76 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 Gene3D G3DSA:1.10.357.10 21 212 8.2E-27 T 29-03-2018 MSG_RS22010 8ac73bdd8104b9f56770c8401943e107 212 SUPERFAMILY SSF46689 21 86 6.98E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 Gene3D G3DSA:1.25.40.10 515 832 2.4E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 SUPERFAMILY SSF46894 843 911 7.14E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 851 865 3.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 881 893 3.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 865 881 3.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 SUPERFAMILY SSF48452 546 729 4.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 Pfam PF00196 Bacterial regulatory proteins, luxR family 850 902 9.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 SUPERFAMILY SSF52540 24 175 1.6E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 Gene3D G3DSA:3.40.50.300 21 300 1.9E-9 T 29-03-2018 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 Pfam PF13191 AAA ATPase domain 27 169 7.5E-12 T 29-03-2018 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 SMART SM00421 848 905 4.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 Gene3D G3DSA:1.10.10.10 841 912 7.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18395 80ecfd77bd89ad8685790a96014f494c 912 ProSitePatterns PS00622 LuxR-type HTH domain signature. 865 892 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS09780 73ef35dacf2b8e6475c0bc96eb143495 292 SUPERFAMILY SSF55486 136 236 8.71E-6 T 29-03-2018 MSG_RS09780 73ef35dacf2b8e6475c0bc96eb143495 292 Pfam PF04228 Putative neutral zinc metallopeptidase 13 286 7.7E-76 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative MSG_RS20680 0ec5fb4850b6eec0a45d768906f33de1 87 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 15 86 2.0E-26 T 29-03-2018 IPR020311 Uncharacterised protein family, Rv0898c MSG_RS20680 0ec5fb4850b6eec0a45d768906f33de1 87 Pfam PF10944 Protein of unknown function (DUF2630) 9 86 2.3E-32 T 29-03-2018 IPR020311 Uncharacterised protein family, Rv0898c MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 Pfam PF00069 Protein kinase domain 20 262 2.2E-44 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 SUPERFAMILY SSF52833 417 602 6.15E-15 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 SUPERFAMILY SSF56112 14 312 2.43E-69 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 Gene3D G3DSA:3.30.200.20 7 112 6.0E-18 T 29-03-2018 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 SMART SM00220 17 273 5.3E-54 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 Pfam PF13462 Thioredoxin 426 599 1.0E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 Gene3D G3DSA:1.10.510.10 113 290 5.9E-43 T 29-03-2018 MSG_RS12065 2c3aa4c8323de969d773b86d31aabcff 603 Gene3D G3DSA:3.40.30.10 425 603 2.4E-21 T 29-03-2018 MSG_RS04625 2f0e10e849aacfe7c86926d160df41df 321 Pfam PF04072 Leucine carboxyl methyltransferase 21 214 5.1E-66 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS04625 2f0e10e849aacfe7c86926d160df41df 321 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 290 6.5E-83 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS04625 2f0e10e849aacfe7c86926d160df41df 321 Gene3D G3DSA:3.40.50.150 4 295 2.4E-58 T 29-03-2018 MSG_RS04625 2f0e10e849aacfe7c86926d160df41df 321 SUPERFAMILY SSF53335 17 311 6.19E-81 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS09195 9f3a7cf7372723dabe2e83a6990537a0 259 Pfam PF01872 RibD C-terminal domain 40 252 7.6E-43 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MSG_RS09195 9f3a7cf7372723dabe2e83a6990537a0 259 Gene3D G3DSA:3.40.430.10 25 259 1.4E-43 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS09195 9f3a7cf7372723dabe2e83a6990537a0 259 SUPERFAMILY SSF53597 39 257 9.95E-41 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS05360 9fb2052bd54080aa0b9b39b872890791 244 SUPERFAMILY SSF53335 12 186 1.22E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05360 9fb2052bd54080aa0b9b39b872890791 244 Gene3D G3DSA:3.40.50.150 2 226 6.0E-33 T 29-03-2018 MSG_RS05360 9fb2052bd54080aa0b9b39b872890791 244 Pfam PF08241 Methyltransferase domain 43 132 2.4E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 Gene3D G3DSA:3.20.20.60 4 410 2.3E-145 T 29-03-2018 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 ProSitePatterns PS00161 Isocitrate lyase signature. 189 194 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 252 427 1.7E-86 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 11 251 7.7E-108 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 PIRSF PIRSF001362 3 428 3.2E-233 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 Pfam PF00463 Isocitrate lyase family 253 426 2.4E-47 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 Pfam PF00463 Isocitrate lyase family 11 251 2.7E-52 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS03365 7102cdb9216302028ad87ab403faf7c7 428 SUPERFAMILY SSF51621 8 427 6.73E-155 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 7.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 Gene3D G3DSA:1.10.10.60 16 49 1.2E-12 T 29-03-2018 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 4.8E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 Gene3D G3DSA:1.10.260.40 50 221 6.6E-10 T 29-03-2018 MSG_RS12490 7b00bed8c045327e308b980f69153db2 222 SUPERFAMILY SSF46689 11 88 2.03E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00380 ca41659045e95d26eeee578f6b869cbf 172 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 32.216 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MSG_RS00380 ca41659045e95d26eeee578f6b869cbf 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 172 1.3E-38 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MSG_RS00380 ca41659045e95d26eeee578f6b869cbf 172 Pfam PF00436 Single-strand binding protein family 6 106 7.5E-31 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MSG_RS00380 ca41659045e95d26eeee578f6b869cbf 172 Gene3D G3DSA:2.40.50.140 2 119 2.6E-41 T 29-03-2018 MSG_RS00380 ca41659045e95d26eeee578f6b869cbf 172 SUPERFAMILY SSF50249 6 172 1.46E-48 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 59 3.4E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 Gene3D G3DSA:1.10.10.60 7 60 2.2E-17 T 29-03-2018 MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 Gene3D G3DSA:1.10.357.10 61 202 2.4E-17 T 29-03-2018 MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS13820 7007133ae23cdd3ab4708abdf598f476 202 SUPERFAMILY SSF46689 7 62 5.67E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06640 9fe39e1ccd3edcc0681e89ae262cb487 411 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS06640 9fe39e1ccd3edcc0681e89ae262cb487 411 SUPERFAMILY SSF103473 2 410 4.45E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06640 9fe39e1ccd3edcc0681e89ae262cb487 411 Gene3D G3DSA:1.20.1250.20 203 411 1.2E-19 T 29-03-2018 MSG_RS06640 9fe39e1ccd3edcc0681e89ae262cb487 411 Gene3D G3DSA:1.20.1250.20 1 202 4.9E-19 T 29-03-2018 MSG_RS06640 9fe39e1ccd3edcc0681e89ae262cb487 411 Pfam PF07690 Major Facilitator Superfamily 37 348 2.5E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS13685 ca69c5ee913831ed735108fdb1e11195 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 7.2E-50 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MSG_RS13685 ca69c5ee913831ed735108fdb1e11195 293 Gene3D G3DSA:3.20.20.360 1 263 8.8E-61 T 29-03-2018 MSG_RS13685 ca69c5ee913831ed735108fdb1e11195 293 PIRSF PIRSF015582 1 293 3.5E-84 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like MSG_RS13685 ca69c5ee913831ed735108fdb1e11195 293 SUPERFAMILY SSF51621 5 233 6.85E-69 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS10125 d1c2f324130cf55a484d68f8200cf65d 409 Gene3D G3DSA:1.20.1250.20 14 208 9.0E-15 T 29-03-2018 MSG_RS10125 d1c2f324130cf55a484d68f8200cf65d 409 Gene3D G3DSA:1.20.1250.20 209 397 5.1E-15 T 29-03-2018 MSG_RS10125 d1c2f324130cf55a484d68f8200cf65d 409 Pfam PF07690 Major Facilitator Superfamily 33 361 2.7E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS10125 d1c2f324130cf55a484d68f8200cf65d 409 SUPERFAMILY SSF103473 18 390 9.94E-35 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 256 406 3.4E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Gene3D G3DSA:1.10.540.10 1 146 2.4E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 145 1.5E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 SUPERFAMILY SSF47203 254 409 1.22E-40 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 149 244 3.1E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 SUPERFAMILY SSF56645 27 267 6.28E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Gene3D G3DSA:2.40.110.10 149 243 6.3E-33 T 29-03-2018 MSG_RS06795 44225cff242c13759df2c03096c5594c 412 Gene3D G3DSA:1.20.140.10 244 412 4.8E-44 T 29-03-2018 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 64 73 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 Pfam PF07687 Peptidase dimerisation domain 166 264 9.0E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 Gene3D G3DSA:3.30.70.360 170 276 3.3E-23 T 29-03-2018 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 Gene3D G3DSA:3.40.630.10 3 169 1.5E-19 T 29-03-2018 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 5 353 7.9E-158 T 29-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 SUPERFAMILY SSF53187 274 352 1.03E-42 T 29-03-2018 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 SUPERFAMILY SSF53187 7 178 1.03E-42 T 29-03-2018 MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 SUPERFAMILY SSF55031 166 271 5.53E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS18900 32ba58efb6c218e9c5ffcfa5b3e90fbc 354 Pfam PF01546 Peptidase family M20/M25/M40 65 352 7.0E-22 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Gene3D G3DSA:1.10.540.10 1 121 1.6E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 SUPERFAMILY SSF56645 2 245 6.02E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 220 7.8E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 121 1.0E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Gene3D G3DSA:2.40.110.10 122 219 2.9E-34 T 29-03-2018 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 SUPERFAMILY SSF47203 232 381 1.83E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Gene3D G3DSA:1.20.140.10 220 382 4.1E-32 T 29-03-2018 MSG_RS19275 80c5ed3b9309e3a9af8ebf6e0b0fdf19 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 377 3.9E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS03680 c7f32c264d6bed83dcee54aa2b4036ba 202 Gene3D G3DSA:3.40.50.1240 1 200 2.8E-34 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS03680 c7f32c264d6bed83dcee54aa2b4036ba 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 191 1.4E-37 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS03680 c7f32c264d6bed83dcee54aa2b4036ba 202 SMART SM00855 6 158 2.4E-17 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS03680 c7f32c264d6bed83dcee54aa2b4036ba 202 SUPERFAMILY SSF53254 5 195 5.89E-39 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS14310 28d3db0bec6755a3255e4a4000129383 376 SUPERFAMILY SSF54593 172 332 1.59E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS14310 28d3db0bec6755a3255e4a4000129383 376 SUPERFAMILY SSF54593 28 144 4.01E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS14310 28d3db0bec6755a3255e4a4000129383 376 Gene3D G3DSA:3.10.180.10 172 332 7.1E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS14310 28d3db0bec6755a3255e4a4000129383 376 Gene3D G3DSA:3.10.180.10 32 153 2.0E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS14310 28d3db0bec6755a3255e4a4000129383 376 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 180 302 7.8E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 SUPERFAMILY SSF51621 2 30 1.08E-49 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 SUPERFAMILY SSF51621 248 422 1.08E-49 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 Gene3D G3DSA:2.40.33.10 144 235 9.5E-14 T 29-03-2018 MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 Gene3D G3DSA:3.20.20.60 236 414 1.1E-38 T 29-03-2018 MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 SUPERFAMILY SSF50800 153 248 9.77E-12 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MSG_RS14230 eb9de01ac454965a387082503b2a033f 437 Pfam PF00224 Pyruvate kinase, barrel domain 154 413 3.3E-38 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 Gene3D G3DSA:3.40.190.10 146 258 6.5E-18 T 29-03-2018 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 PIRSF PIRSF004846 1 258 1.6E-60 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 SUPERFAMILY SSF53850 37 257 3.22E-52 T 29-03-2018 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 Gene3D G3DSA:3.40.190.10 37 145 2.1E-23 T 29-03-2018 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 Pfam PF13531 Bacterial extracellular solute-binding protein 38 255 9.8E-41 T 29-03-2018 MSG_RS12990 4520d62ac7240ae3f1759764240f9b2f 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 43 252 3.8E-35 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MSG_RS23435 6cae827055377f4a926b6ffc4be683c8 207 Gene3D G3DSA:3.90.70.10 51 207 7.4E-18 T 29-03-2018 MSG_RS23435 6cae827055377f4a926b6ffc4be683c8 207 Pfam PF13529 Peptidase_C39 like family 57 177 1.7E-8 T 29-03-2018 MSG_RS23435 6cae827055377f4a926b6ffc4be683c8 207 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 37 206 3.0E-35 T 29-03-2018 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 1.4E-148 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.5E-29 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 286 293 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Gene3D G3DSA:3.90.600.10 327 417 1.4E-27 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 39.249 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Gene3D G3DSA:3.40.50.20 2 84 9.9E-33 T 29-03-2018 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 SMART SM01210 327 416 3.1E-38 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 SUPERFAMILY SSF51246 325 415 1.57E-24 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 413 2.3E-25 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 SMART SM01209 101 292 6.6E-103 T 29-03-2018 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 292 2.8E-64 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 SUPERFAMILY SSF56059 102 317 2.05E-48 T 29-03-2018 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Gene3D G3DSA:3.30.1490.20 85 186 3.2E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 SUPERFAMILY SSF52440 2 101 9.06E-31 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS21985 ace26664f6e65321d154008d2368c92b 422 Gene3D G3DSA:3.30.470.20 188 325 6.2E-53 T 29-03-2018 MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 Gene3D G3DSA:3.40.50.720 1 320 1.4E-42 T 29-03-2018 MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 515 534 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 440 451 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 495 503 9.9E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 Pfam PF00106 short chain dehydrogenase 366 553 1.7E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 365 549 6.8E-5 T 29-03-2018 MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 Pfam PF07993 Male sterility protein 5 227 2.9E-39 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 SUPERFAMILY SSF51735 361 582 7.25E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 SUPERFAMILY SSF51735 1 275 9.45E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 366 383 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 489 505 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 515 534 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 440 451 1.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05200 82a95c1397bc67348883525b8bab3699 667 Gene3D G3DSA:3.40.50.720 342 595 4.3E-54 T 29-03-2018 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Gene3D G3DSA:3.40.50.970 349 561 5.6E-29 T 29-03-2018 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 SUPERFAMILY SSF52467 191 349 4.27E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Gene3D G3DSA:3.40.50.1220 193 348 3.6E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 SUPERFAMILY SSF52518 3 183 1.55E-35 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 330 7.1E-28 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Gene3D G3DSA:3.40.50.970 2 192 2.5E-34 T 29-03-2018 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 544 6.1E-24 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 174 7.0E-42 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS01150 fb2936554e5e8f0d36ca8304a994ee50 570 SUPERFAMILY SSF52518 369 558 1.82E-33 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.371 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 Pfam PF00453 Ribosomal protein L20 3 109 2.4E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 6.6E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 Gene3D G3DSA:1.10.1900.20 56 116 1.6E-23 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 3.0E-21 T 29-03-2018 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 PRINTS PR00062 Ribosomal protein L20 signature 12 41 8.5E-36 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 PRINTS PR00062 Ribosomal protein L20 signature 42 71 8.5E-36 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 PRINTS PR00062 Ribosomal protein L20 signature 75 101 8.5E-36 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11460 624271aa1acfe511a386362994e7e5a0 129 SUPERFAMILY SSF74731 3 117 2.22E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 Gene3D G3DSA:1.20.58.280 322 380 7.1E-4 T 29-03-2018 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 Gene3D G3DSA:2.40.10.10 45 215 4.5E-15 T 29-03-2018 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 Pfam PF13365 Trypsin-like peptidase domain 94 287 2.6E-20 T 29-03-2018 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 Gene3D G3DSA:2.40.10.10 216 314 1.9E-16 T 29-03-2018 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 SUPERFAMILY SSF50494 173 306 9.09E-28 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 SUPERFAMILY SSF50494 17 133 9.09E-28 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 PRINTS PR00834 HtrA/DegQ protease family signature 103 115 2.5E-5 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 PRINTS PR00834 HtrA/DegQ protease family signature 220 244 2.5E-5 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 PRINTS PR00834 HtrA/DegQ protease family signature 280 297 2.5E-5 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 PRINTS PR00834 HtrA/DegQ protease family signature 258 275 2.5E-5 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS03910 91a5e3a8b084dba67ca50c349bf5a90b 472 SUPERFAMILY SSF48452 326 379 4.94E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 SUPERFAMILY SSF158791 167 288 9.02E-21 T 29-03-2018 MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Pfam PF00571 CBS domain 293 352 0.0055 T 29-03-2018 IPR000644 CBS domain MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Pfam PF00571 CBS domain 357 410 4.5E-11 T 29-03-2018 IPR000644 CBS domain MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Gene3D G3DSA:2.30.30.240 15 88 5.0E-8 T 29-03-2018 MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 SMART SM00116 364 412 9.5E-7 T 29-03-2018 IPR000644 CBS domain MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Gene3D G3DSA:3.10.580.10 287 416 1.8E-18 T 29-03-2018 MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 SMART SM00924 187 292 2.6E-25 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Pfam PF03448 MgtE intracellular N domain 188 289 5.9E-22 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 Gene3D G3DSA:1.25.60.10 177 286 4.5E-16 T 29-03-2018 MSG_RS16115 bb99c4dfdcdb4ec1a9fc7b15b6d3939a 446 SUPERFAMILY SSF54631 292 416 4.8E-25 T 29-03-2018 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 Gene3D G3DSA:3.20.20.10 58 295 1.1E-62 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 445 35.915 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 Gene3D G3DSA:2.40.37.10 296 446 3.4E-40 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 SUPERFAMILY SSF51419 51 312 3.2E-68 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 3.9E-21 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01181 Diaminopimelate decarboxylase signature 329 347 3.9E-21 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01181 Diaminopimelate decarboxylase signature 183 192 3.9E-21 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01181 Diaminopimelate decarboxylase signature 412 434 3.9E-21 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 104 402 1.4E-16 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 60 309 2.2E-61 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 402 415 1.2E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 1.2E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 211 224 1.2E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 1.2E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 300 319 1.2E-17 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 28 444 1.9E-125 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19865 b392043b98a34af7589c9de1e2013b66 446 SUPERFAMILY SSF50621 286 444 6.07E-45 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS02465 45dcdb9725862f6700410ab81ab10596 165 SUPERFAMILY SSF54427 7 147 4.59E-36 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS02465 45dcdb9725862f6700410ab81ab10596 165 Gene3D G3DSA:3.10.450.50 6 156 1.7E-29 T 29-03-2018 MSG_RS02465 45dcdb9725862f6700410ab81ab10596 165 Pfam PF13577 SnoaL-like domain 11 134 1.7E-28 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS03395 46344bd8704cf8f16e6ed5e72590a83f 143 SMART SM00530 25 80 1.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS03395 46344bd8704cf8f16e6ed5e72590a83f 143 SUPERFAMILY SSF47413 18 82 3.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS03395 46344bd8704cf8f16e6ed5e72590a83f 143 Gene3D G3DSA:1.10.10.10 92 135 0.3 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03395 46344bd8704cf8f16e6ed5e72590a83f 143 Gene3D G3DSA:1.10.260.40 11 85 1.9E-19 T 29-03-2018 MSG_RS03395 46344bd8704cf8f16e6ed5e72590a83f 143 Pfam PF13560 Helix-turn-helix domain 22 78 5.3E-14 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 Gene3D G3DSA:1.20.1250.20 21 213 3.6E-36 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 Gene3D G3DSA:1.20.1250.20 269 515 4.3E-31 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 SUPERFAMILY SSF103473 481 504 2.49E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 SUPERFAMILY SSF103473 23 211 2.49E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 SUPERFAMILY SSF103473 265 437 2.49E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 503 1.5E-74 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 Pfam PF07690 Major Facilitator Superfamily 36 428 9.8E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 PRINTS PR01036 Tetracycline resistance protein TetB signature 154 178 3.0E-5 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 PRINTS PR01036 Tetracycline resistance protein TetB signature 219 237 3.0E-5 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 PRINTS PR01036 Tetracycline resistance protein TetB signature 418 437 3.0E-5 T 29-03-2018 MSG_RS13155 f7eeebbfc3e588ba7faa89f6b37875be 693 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 3.0E-5 T 29-03-2018 MSG_RS22550 b7bbbd967076ad04b604d7322074bd50 356 Pfam PF03060 Nitronate monooxygenase 5 341 5.6E-107 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS22550 b7bbbd967076ad04b604d7322074bd50 356 SUPERFAMILY SSF51412 1 249 2.59E-59 T 29-03-2018 MSG_RS22550 b7bbbd967076ad04b604d7322074bd50 356 SUPERFAMILY SSF51412 309 343 2.59E-59 T 29-03-2018 MSG_RS22550 b7bbbd967076ad04b604d7322074bd50 356 Gene3D G3DSA:3.20.20.70 1 355 8.7E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS23480 f4a5959edaf72770d1552680a599df34 430 Gene3D G3DSA:3.90.1150.10 290 414 7.4E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS23480 f4a5959edaf72770d1552680a599df34 430 Pfam PF12897 Alanine-glyoxylate amino-transferase 6 423 2.8E-183 T 29-03-2018 IPR024551 Aminotransferase, putative MSG_RS23480 f4a5959edaf72770d1552680a599df34 430 Gene3D G3DSA:3.40.640.10 58 289 2.4E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS23480 f4a5959edaf72770d1552680a599df34 430 SUPERFAMILY SSF53383 60 412 8.92E-42 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS13665 44f893539354abc81d99e8d60495c230 272 Pfam PF00296 Luciferase-like monooxygenase 15 228 3.0E-27 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS13665 44f893539354abc81d99e8d60495c230 272 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 7 269 2.6E-118 T 29-03-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 MSG_RS13665 44f893539354abc81d99e8d60495c230 272 Gene3D G3DSA:3.20.20.30 4 263 4.8E-42 T 29-03-2018 MSG_RS13665 44f893539354abc81d99e8d60495c230 272 SUPERFAMILY SSF51679 5 246 3.09E-42 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS10250 678d4d8e0f377942e172587d6338b4ed 105 Gene3D G3DSA:1.10.8.50 48 104 2.9E-5 T 29-03-2018 MSG_RS10250 678d4d8e0f377942e172587d6338b4ed 105 SUPERFAMILY SSF46946 53 102 2.59E-5 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS10250 678d4d8e0f377942e172587d6338b4ed 105 PIRSF PIRSF002134 37 104 0.0023 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS23250 6ee26e0762565a7986f89b31f82373d0 333 SUPERFAMILY SSF48613 129 289 1.33E-8 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MSG_RS23250 6ee26e0762565a7986f89b31f82373d0 333 Gene3D G3DSA:1.20.910.10 122 332 2.1E-30 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MSG_RS23250 6ee26e0762565a7986f89b31f82373d0 333 SMART SM01236 166 271 1.4E-37 T 29-03-2018 MSG_RS23250 6ee26e0762565a7986f89b31f82373d0 333 Pfam PF14518 Iron-containing redox enzyme 134 305 3.6E-44 T 29-03-2018 IPR028201 PqqC-like protein MSG_RS06985 ca4a3ea9ab9d71ac13938ac6f17b1027 364 SUPERFAMILY SSF50022 4 119 4.06E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS06985 ca4a3ea9ab9d71ac13938ac6f17b1027 364 Gene3D G3DSA:3.90.380.10 110 329 4.1E-27 T 29-03-2018 MSG_RS06985 ca4a3ea9ab9d71ac13938ac6f17b1027 364 SUPERFAMILY SSF55961 111 327 6.87E-23 T 29-03-2018 MSG_RS06985 ca4a3ea9ab9d71ac13938ac6f17b1027 364 Pfam PF00355 Rieske [2Fe-2S] domain 8 93 5.9E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS06985 ca4a3ea9ab9d71ac13938ac6f17b1027 364 Gene3D G3DSA:2.102.10.10 4 109 6.1E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS15025 d4caa6a0e73bb428d7b8e89a6493528e 151 SUPERFAMILY SSF49777 17 143 2.22E-28 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS15025 d4caa6a0e73bb428d7b8e89a6493528e 151 Gene3D G3DSA:3.90.280.10 4 151 3.9E-29 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS15025 d4caa6a0e73bb428d7b8e89a6493528e 151 Pfam PF01161 Phosphatidylethanolamine-binding protein 18 148 2.4E-21 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 Gene3D G3DSA:3.40.1360.10 87 174 1.2E-37 T 29-03-2018 MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 2.9E-82 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 SMART SM00493 79 168 2.8E-17 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 Gene3D G3DSA:3.10.180.10 4 86 0.0014 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.786 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 Pfam PF02132 RecR protein 39 77 4.8E-14 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 Pfam PF13662 Toprim domain 79 175 1.3E-22 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 SUPERFAMILY SSF111304 2 202 1.83E-68 T 29-03-2018 IPR023627 Recombination protein RecR MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MSG_RS23440 21378adca41e44f1ae8531d83ce3bf42 203 SMART SM00278 11 30 0.0059 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS23255 4d2c6941bd20ded38145b20e1e771b2f 69 SMART SM00704 17 61 1.7E-7 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MSG_RS23255 4d2c6941bd20ded38145b20e1e771b2f 69 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 56 2.1E-15 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF52151 758 853 1.07E-42 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF52151 565 694 1.07E-42 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 1.5E-32 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF47336 1017 1083 5.37E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF55048 694 757 1.44E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 860 1.1E-36 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 280 2.2E-71 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.40.366.10 748 871 1.1E-13 T 29-03-2018 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.40.640.10 1165 1404 1.3E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF53383 1151 1510 2.31E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 1358 1367 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 418 500 5.6E-8 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.90.1150.10 1405 1514 1.7E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.40.366.10 564 704 5.9E-24 T 29-03-2018 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SMART SM00825 Beta-ketoacyl synthase 11 457 2.2E-102 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.30.70.250 705 747 5.9E-17 T 29-03-2018 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:1.10.1200.10 995 1101 5.4E-7 T 29-03-2018 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.40.47.10 1 287 9.8E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Pfam PF00698 Acyl transferase domain 567 847 2.3E-36 T 29-03-2018 IPR014043 Acyl transferase MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Gene3D G3DSA:3.40.47.10 297 459 1.7E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 Pfam PF00155 Aminotransferase class I and II 1161 1502 2.0E-47 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF53901 178 400 5.77E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF53901 7 128 5.77E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 SUPERFAMILY SSF53901 432 453 5.77E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS01380 65ec58075a9d2901f013058529cbd821 1517 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 Gene3D G3DSA:1.10.630.10 4 419 1.0E-82 T 29-03-2018 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 104 115 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 341 356 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 215 237 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 362 371 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 150 166 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 313 340 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 371 382 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 296 307 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00359 B-class P450 signature 167 182 2.7E-57 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00385 P450 superfamily signature 362 371 2.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00385 P450 superfamily signature 296 307 2.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00385 P450 superfamily signature 371 382 2.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 PRINTS PR00385 P450 superfamily signature 261 278 2.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 Pfam PF00067 Cytochrome P450 100 392 2.5E-30 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS23650 60b2d3d67a9419ba00a4c865a77de60e 419 SUPERFAMILY SSF48264 16 418 8.51E-96 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 Pfam PF00067 Cytochrome P450 218 384 1.0E-24 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 147 163 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 333 348 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 101 112 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 206 228 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 355 364 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 288 299 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 164 179 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 305 332 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 PRINTS PR00359 B-class P450 signature 364 375 1.0E-39 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 Gene3D G3DSA:1.10.630.10 4 422 6.5E-66 T 29-03-2018 MSG_RS21040 c5541f2cf33423f3c87cdbc1ed1a6494 431 SUPERFAMILY SSF48264 13 421 2.75E-83 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07110 25ec5f979fd509d4740560f8d78e9a62 375 Gene3D G3DSA:1.10.600.10 25 375 8.3E-76 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS07110 25ec5f979fd509d4740560f8d78e9a62 375 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 253 265 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS07110 25ec5f979fd509d4740560f8d78e9a62 375 Pfam PF00348 Polyprenyl synthetase 67 310 4.1E-46 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MSG_RS07110 25ec5f979fd509d4740560f8d78e9a62 375 SUPERFAMILY SSF48576 35 373 3.04E-70 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS22140 4ba6356af40b53954471ba24f88b7fba 214 SUPERFAMILY SSF50494 37 197 1.65E-18 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS22140 4ba6356af40b53954471ba24f88b7fba 214 Gene3D G3DSA:2.40.10.10 33 119 2.6E-12 T 29-03-2018 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 430 1.6E-156 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 SUPERFAMILY SSF51338 2 55 1.87E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 SUPERFAMILY SSF51338 372 431 1.87E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 430 43.462 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 SUPERFAMILY SSF51556 56 371 9.89E-98 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 ProSitePatterns PS00483 Dihydroorotase signature 2. 306 317 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 Pfam PF01979 Amidohydrolase family 52 425 1.5E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 Gene3D G3DSA:2.30.40.10 1 70 7.3E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS10225 8b842bad3a738667eda5290ff3813e8f 434 Gene3D G3DSA:3.20.20.140 71 393 4.0E-96 T 29-03-2018 MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 Pfam PF00106 short chain dehydrogenase 9 197 2.5E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 SUPERFAMILY SSF51735 3 245 1.69E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 Gene3D G3DSA:3.40.50.720 1 279 1.1E-58 T 29-03-2018 MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 0.0051 T 29-03-2018 MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21380 f1bf3056f89bcc6e9dafcd4a566585c5 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS23260 6ce9b1563a8098a3e2f35af2911d9ab5 234 Gene3D G3DSA:3.40.50.150 22 224 3.6E-26 T 29-03-2018 MSG_RS23260 6ce9b1563a8098a3e2f35af2911d9ab5 234 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 23 203 2.5E-32 T 29-03-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 MSG_RS23260 6ce9b1563a8098a3e2f35af2911d9ab5 234 SUPERFAMILY SSF53335 23 171 6.37E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23260 6ce9b1563a8098a3e2f35af2911d9ab5 234 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 113 119 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MSG_RS23260 6ce9b1563a8098a3e2f35af2911d9ab5 234 Pfam PF05175 Methyltransferase small domain 30 123 7.6E-15 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MSG_RS16550 5b35db874d65cf5f055e7ec0afd7224e 422 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 25 309 4.2E-65 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16550 5b35db874d65cf5f055e7ec0afd7224e 422 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 157 406 3.6E-85 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS16550 5b35db874d65cf5f055e7ec0afd7224e 422 Pfam PF02470 MlaD protein 54 127 6.3E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 282 40.804 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 SMART SM01232 141 233 2.7E-37 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 121 2.0E-33 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 ProSitePatterns PS01242 Zinc finger FPG-type signature. 257 281 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 SMART SM00898 2 122 1.4E-42 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 SUPERFAMILY SSF46946 140 230 2.36E-25 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 SUPERFAMILY SSF57716 233 282 3.14E-16 T 29-03-2018 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 SUPERFAMILY SSF81624 2 146 1.31E-32 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 141 228 1.0E-24 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Pfam PF06827 Zinc finger found in FPG and IleRS 255 283 8.5E-11 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Gene3D G3DSA:3.20.190.10 2 132 2.2E-39 T 29-03-2018 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 281 1.0E-97 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MSG_RS08080 1fae5d235a37bdaf3cac12233fb95b5f 286 Gene3D G3DSA:1.10.8.50 133 282 3.5E-45 T 29-03-2018 MSG_RS19975 b2f62f6a4f25e01187c1a6a7e70b7e83 395 SUPERFAMILY SSF140459 3 174 4.97E-58 T 29-03-2018 MSG_RS19975 b2f62f6a4f25e01187c1a6a7e70b7e83 395 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 315 389 8.5E-14 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS19975 b2f62f6a4f25e01187c1a6a7e70b7e83 395 Pfam PF00823 PPE family 6 162 1.4E-58 T 29-03-2018 IPR000030 PPE family MSG_RS19975 b2f62f6a4f25e01187c1a6a7e70b7e83 395 Gene3D G3DSA:1.10.287.1060 21 104 1.2E-6 T 29-03-2018 MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 SUPERFAMILY SSF51735 4 246 5.25E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 2.9E-64 T 29-03-2018 MSG_RS22000 04200c6b52021d678289a1deea735cbd 249 Gene3D G3DSA:3.40.50.720 1 247 9.5E-70 T 29-03-2018 MSG_RS21450 50133882f2bddf0250b9c443960f0d59 433 Gene3D G3DSA:3.20.20.30 3 427 5.0E-72 T 29-03-2018 MSG_RS21450 50133882f2bddf0250b9c443960f0d59 433 SUPERFAMILY SSF51679 1 354 2.09E-67 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS21450 50133882f2bddf0250b9c443960f0d59 433 Pfam PF00296 Luciferase-like monooxygenase 22 326 4.8E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 Pfam PF03176 MMPL family 518 748 2.2E-26 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 Pfam PF03176 MMPL family 72 406 2.5E-47 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 SUPERFAMILY SSF82866 141 370 6.93E-24 T 29-03-2018 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 Gene3D G3DSA:1.20.1640.10 157 377 9.0E-28 T 29-03-2018 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 Gene3D G3DSA:1.20.1640.10 521 735 5.7E-28 T 29-03-2018 MSG_RS21585 d25950a14c962d3b244b52aef9980b0b 753 SUPERFAMILY SSF82866 526 738 2.49E-26 T 29-03-2018 MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 Pfam PF13452 N-terminal half of MaoC dehydratase 25 159 1.8E-18 T 29-03-2018 MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 237 299 2.1E-20 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 SUPERFAMILY SSF50249 186 304 1.42E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 SUPERFAMILY SSF54637 26 179 6.91E-20 T 29-03-2018 IPR029069 HotDog domain MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 Gene3D G3DSA:3.10.129.10 8 183 5.8E-31 T 29-03-2018 MSG_RS22485 bc2c55233fed27dd36982516739ab881 320 Gene3D G3DSA:2.40.50.140 241 301 7.5E-19 T 29-03-2018 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 Gene3D G3DSA:2.40.180.10 4 312 1.5E-66 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 SMART SM01060 1 312 5.5E-6 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 PRINTS PR00067 Catalase signature 104 122 3.1E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 PRINTS PR00067 Catalase signature 285 311 3.1E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 PRINTS PR00067 Catalase signature 24 46 3.1E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 PRINTS PR00067 Catalase signature 253 280 3.1E-6 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 PIRSF PIRSF000296 4 312 8.7E-96 T 29-03-2018 IPR024168 Catalase, SrpA-type, predicted MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 Pfam PF00199 Catalase 31 309 1.5E-21 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS00600 f3b2edd02fd3d97a3fd725c02a67cf56 312 SUPERFAMILY SSF56634 18 309 4.71E-70 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 113 123 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 295 311 2.7E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 109 122 2.7E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 73 92 2.7E-13 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 SUPERFAMILY SSF52743 59 355 5.24E-58 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 Gene3D G3DSA:3.40.50.200 40 354 7.1E-62 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 62 406 2.1E-114 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 Pfam PF00082 Subtilase family 73 345 1.1E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 78 88 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MSG_RS04875 e32cb60c2594f5799bed23ad66f69431 428 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 296 306 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MSG_RS15145 4dd6960376355ac0816b9f6b9cc98d1d 253 SUPERFAMILY SSF54637 6 81 6.38E-10 T 29-03-2018 IPR029069 HotDog domain MSG_RS15145 4dd6960376355ac0816b9f6b9cc98d1d 253 SUPERFAMILY SSF54637 137 245 2.76E-6 T 29-03-2018 IPR029069 HotDog domain MSG_RS15145 4dd6960376355ac0816b9f6b9cc98d1d 253 Gene3D G3DSA:3.10.129.10 1 75 5.5E-17 T 29-03-2018 MSG_RS15145 4dd6960376355ac0816b9f6b9cc98d1d 253 Gene3D G3DSA:3.10.129.10 76 253 3.1E-8 T 29-03-2018 MSG_RS15145 4dd6960376355ac0816b9f6b9cc98d1d 253 Pfam PF13622 Thioesterase-like superfamily 2 244 3.7E-40 T 29-03-2018 MSG_RS15970 b059ca328155fdb80ca1a2e8c9da1bb0 144 SUPERFAMILY SSF141066 48 143 8.5E-20 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin MSG_RS15970 b059ca328155fdb80ca1a2e8c9da1bb0 144 Pfam PF09394 Chagasin family peptidase inhibitor I42 51 130 5.7E-18 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 118 1.5E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 Gene3D G3DSA:1.10.540.10 1 110 1.1E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 SUPERFAMILY SSF56645 1 213 3.4E-30 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 214 359 3.1E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 SUPERFAMILY SSF47203 219 360 3.87E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 Gene3D G3DSA:2.40.110.10 111 208 3.6E-10 T 29-03-2018 MSG_RS22310 04495573ed7fcbbb7c4df68dc872408f 365 Gene3D G3DSA:1.20.140.10 209 365 7.6E-28 T 29-03-2018 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Gene3D G3DSA:3.90.1150.10 758 883 6.7E-10 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 SUPERFAMILY SSF56112 92 153 1.66E-23 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS21590 08333985e40790024afbe96032b12f5f 886 SUPERFAMILY SSF56112 199 360 1.66E-23 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Pfam PF00202 Aminotransferase class-III 476 851 4.1E-56 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Pfam PF03109 ABC1 family 108 224 5.1E-24 T 29-03-2018 IPR004147 UbiB domain MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Gene3D G3DSA:1.10.510.10 236 449 4.1E-6 T 29-03-2018 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Gene3D G3DSA:3.40.640.10 614 757 3.5E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Gene3D G3DSA:3.30.200.20 98 235 2.5E-18 T 29-03-2018 MSG_RS21590 08333985e40790024afbe96032b12f5f 886 SUPERFAMILY SSF53383 469 877 4.26E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS21590 08333985e40790024afbe96032b12f5f 886 Gene3D G3DSA:3.90.1150.10 454 613 1.6E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Gene3D G3DSA:2.30.38.10 359 442 2.2E-17 T 29-03-2018 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Gene3D G3DSA:3.30.300.30 443 545 1.2E-31 T 29-03-2018 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Gene3D G3DSA:3.40.50.980 47 207 2.9E-27 T 29-03-2018 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Gene3D G3DSA:3.40.50.980 208 358 2.9E-31 T 29-03-2018 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Pfam PF00501 AMP-binding enzyme 53 449 1.0E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 SUPERFAMILY SSF56801 50 544 6.54E-121 T 29-03-2018 MSG_RS10430 3c07832db03783b762a40b5f2c82020b 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 533 2.7E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 SUPERFAMILY SSF52540 6 245 8.34E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 Gene3D G3DSA:2.40.50.140 283 338 7.6E-16 T 29-03-2018 MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 Gene3D G3DSA:2.40.50.100 242 281 5.8E-10 T 29-03-2018 MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 SUPERFAMILY SSF50331 238 355 1.99E-24 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 Gene3D G3DSA:3.40.50.300 1 238 3.9E-65 T 29-03-2018 MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 Pfam PF08402 TOBE domain 275 348 2.7E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 Pfam PF00005 ABC transporter 21 163 1.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 SMART SM00382 30 213 7.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS14435 82faa045c2a8da97790781bf7c1a1444 357 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS20130 0c2339ac2f5bcf6381e6572988891ff9 202 SUPERFAMILY SSF53697 26 198 1.05E-47 T 29-03-2018 MSG_RS20130 0c2339ac2f5bcf6381e6572988891ff9 202 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 9 197 33.717 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MSG_RS20130 0c2339ac2f5bcf6381e6572988891ff9 202 Pfam PF13580 SIS domain 38 154 3.2E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MSG_RS20130 0c2339ac2f5bcf6381e6572988891ff9 202 Gene3D G3DSA:3.40.50.10490 9 202 1.5E-37 T 29-03-2018 MSG_RS13840 53357dbfb455f8267c0d1c742dd2b5f2 467 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 451 8.3E-123 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS13840 53357dbfb455f8267c0d1c742dd2b5f2 467 SUPERFAMILY SSF52777 49 154 1.63E-8 T 29-03-2018 MSG_RS13840 53357dbfb455f8267c0d1c742dd2b5f2 467 Pfam PF06974 Protein of unknown function (DUF1298) 304 447 2.7E-21 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS13840 53357dbfb455f8267c0d1c742dd2b5f2 467 Gene3D G3DSA:3.30.559.10 18 183 8.3E-5 T 29-03-2018 MSG_RS13840 53357dbfb455f8267c0d1c742dd2b5f2 467 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 261 2.4E-61 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS01655 e5f2a46e650e5a36e98cf7eea048e3c4 234 Gene3D G3DSA:3.30.70.100 7 111 1.0E-7 T 29-03-2018 MSG_RS01655 e5f2a46e650e5a36e98cf7eea048e3c4 234 Gene3D G3DSA:3.30.70.100 119 234 4.0E-9 T 29-03-2018 MSG_RS01655 e5f2a46e650e5a36e98cf7eea048e3c4 234 SUPERFAMILY SSF54909 19 91 1.31E-5 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 Pfam PF00953 Glycosyl transferase family 4 86 276 2.4E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 ProSitePatterns PS01348 MraY family signature 2. 179 190 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 3.3E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 350 22.782 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS15105 ffc0e0cddf2e63e828d6254e64b7828f 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 6.2E-82 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 Gene3D G3DSA:3.30.200.20 15 120 0.0014 T 29-03-2018 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 SUPERFAMILY SSF159245 369 660 1.83E-17 T 29-03-2018 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 Gene3D G3DSA:3.90.1200.10 134 403 1.5E-19 T 29-03-2018 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 Pfam PF02958 Ecdysteroid kinase 42 100 1.3E-5 T 29-03-2018 IPR004119 Protein of unknown function DUF227 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 Pfam PF02958 Ecdysteroid kinase 204 292 1.3E-16 T 29-03-2018 IPR004119 Protein of unknown function DUF227 MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 SMART SM00587 121 298 4.9E-5 T 29-03-2018 IPR015897 CHK kinase-like MSG_RS14495 ca73670316d3a5c22e160f1f702bbeaa 668 SUPERFAMILY SSF56112 11 296 1.27E-31 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.8E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 PRINTS PR00069 Aldo-keto reductase signature 101 119 1.8E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 PRINTS PR00069 Aldo-keto reductase signature 132 149 1.8E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 Gene3D G3DSA:3.20.20.100 7 316 1.6E-70 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 SUPERFAMILY SSF51430 11 301 1.17E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS06500 4e95512b18440485a5293bfd710db58f 323 Pfam PF00248 Aldo/keto reductase family 14 298 2.6E-56 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Pfam PF00271 Helicase conserved C-terminal domain 239 347 1.4E-27 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 SMART SM00490 266 347 1.2E-31 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 SUPERFAMILY SSF52540 82 368 2.58E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 8 549 43.868 T 29-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Gene3D G3DSA:3.40.50.300 5 231 6.5E-57 T 29-03-2018 MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Pfam PF03880 DbpA RNA binding domain 477 544 5.4E-20 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 SMART SM00487 32 230 7.3E-63 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 161 169 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Pfam PF00270 DEAD/DEAH box helicase 37 203 6.5E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS18680 b4df0ef44d1dd9ad5fb5decd06e1e326 576 Gene3D G3DSA:3.40.50.300 232 382 2.6E-46 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 ProSitePatterns PS00012 Phosphopantetheine attachment site. 558 573 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 917 1072 2.1E-32 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF52777 795 1049 2.33E-23 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.30.559.10 597 794 1.7E-18 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SMART SM00823 Phosphopantetheine attachment site 534 602 0.063 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SMART SM00823 Phosphopantetheine attachment site 2024 2093 7.2E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF13193 AMP-binding enzyme C-terminal domain 438 509 1.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF13193 AMP-binding enzyme C-terminal domain 1928 1999 4.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 66 454 4.8E-130 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1554 1944 6.9E-125 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00668 Condensation domain 1079 1511 6.0E-80 T 29-03-2018 IPR001242 Condensation domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00668 Condensation domain 622 963 4.6E-29 T 29-03-2018 IPR001242 Condensation domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2145 2542 5.3E-93 T 29-03-2018 IPR010080 Thioester reductase-like domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.30.559.10 1061 1269 5.6E-36 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:1.10.1200.10 538 596 4.1E-19 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.40.50.720 2142 2465 5.7E-28 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF47336 2016 2089 6.02E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00550 Phosphopantetheine attachment site 537 596 2.5E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00550 Phosphopantetheine attachment site 2026 2089 9.1E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.30.300.30 1915 2029 8.3E-36 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.30.300.30 425 537 1.3E-37 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF52777 609 776 9.67E-28 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.40.50.980 1678 1824 2.0E-31 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.40.50.980 190 336 3.3E-29 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:2.30.38.10 1832 1913 8.9E-21 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:2.30.38.10 342 423 5.2E-21 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00501 AMP-binding enzyme 1533 1920 6.2E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF00501 AMP-binding enzyme 45 430 5.1E-87 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF51735 2145 2453 4.29E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Pfam PF07993 Male sterility protein 2148 2410 4.3E-56 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:1.10.1200.10 2030 2106 1.5E-21 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF47336 526 596 3.4E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.40.50.980 1523 1677 4.3E-48 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 Gene3D G3DSA:3.40.50.980 36 189 1.0E-43 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF56801 5 547 4.45E-147 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF52777 1076 1273 4.67E-37 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF52777 1259 1495 1.11E-53 T 29-03-2018 MSG_RS10895 45a2f8cc37698aa3da1669acc5541d49 2543 SUPERFAMILY SSF56801 1493 2037 2.09E-148 T 29-03-2018 MSG_RS15080 e1f08137c304484e8000f5be4255ee08 314 Pfam PF03799 Cell division protein FtsQ 205 298 3.0E-6 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB MSG_RS15080 e1f08137c304484e8000f5be4255ee08 314 Pfam PF08478 POTRA domain, FtsQ-type 125 192 1.1E-17 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type MSG_RS15080 e1f08137c304484e8000f5be4255ee08 314 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 94 314 18.541 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 Gene3D G3DSA:2.40.10.10 307 410 2.8E-36 T 29-03-2018 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 Pfam PF13180 PDZ domain 420 502 7.4E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 SUPERFAMILY SSF50156 401 503 1.84E-19 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 SUPERFAMILY SSF50494 203 429 4.62E-57 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 SMART SM00228 420 494 1.1E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 Gene3D G3DSA:2.40.10.10 204 306 3.0E-31 T 29-03-2018 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 311 335 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 270 290 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 352 369 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 452 464 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 374 391 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 PRINTS PR00834 HtrA/DegQ protease family signature 243 255 1.4E-45 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 Pfam PF13365 Trypsin-like peptidase domain 234 381 4.2E-35 T 29-03-2018 MSG_RS18795 11bdc25669db1d5ed0ecbe075634f0b3 508 Gene3D G3DSA:2.30.42.10 418 507 9.5E-17 T 29-03-2018 MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 SUPERFAMILY SSF53383 21 374 5.98E-52 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 Pfam PF00266 Aminotransferase class-V 23 367 1.5E-31 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 Gene3D G3DSA:3.40.640.10 26 255 2.9E-31 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 TIGRFAM TIGR04343 egtE_PLP_lyase: ergothioneine biosynthesis PLP-dependent enzyme EgtE 7 373 9.3E-174 T 29-03-2018 IPR027563 Pyridoxal-phosphate-dependent protein EgtE MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 Gene3D G3DSA:3.90.1150.10 256 380 2.4E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS23335 e8434d34a0cdcd2be4e061bbf7876a35 381 Hamap MF_02038 Probable hercynylcysteine sulfoxide lyase [egtE]. 5 374 36.075 T 29-03-2018 IPR027563 Pyridoxal-phosphate-dependent protein EgtE MSG_RS05020 02fd47e0b8e7978ba7abb8c502976ead 156 Gene3D G3DSA:3.40.630.30 3 154 2.8E-32 T 29-03-2018 MSG_RS05020 02fd47e0b8e7978ba7abb8c502976ead 156 Pfam PF00583 Acetyltransferase (GNAT) family 34 130 5.2E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS05020 02fd47e0b8e7978ba7abb8c502976ead 156 SUPERFAMILY SSF55729 9 152 1.48E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS05020 02fd47e0b8e7978ba7abb8c502976ead 156 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 17 150 1.4E-37 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MSG_RS23660 29be0aa1c6f411d7ff9b203562e1229f 453 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 261 2.3E-82 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS23660 29be0aa1c6f411d7ff9b203562e1229f 453 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 451 8.3E-147 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS23660 29be0aa1c6f411d7ff9b203562e1229f 453 Gene3D G3DSA:3.30.559.10 71 187 1.8E-6 T 29-03-2018 MSG_RS23660 29be0aa1c6f411d7ff9b203562e1229f 453 SUPERFAMILY SSF52777 85 162 8.89E-7 T 29-03-2018 MSG_RS23660 29be0aa1c6f411d7ff9b203562e1229f 453 Pfam PF06974 Protein of unknown function (DUF1298) 302 447 2.6E-35 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 SUPERFAMILY SSF52374 7 334 8.63E-94 T 29-03-2018 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 Gene3D G3DSA:1.10.240.10 197 317 9.1E-28 T 29-03-2018 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 335 40.693 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 Gene3D G3DSA:3.40.50.620 1 196 2.6E-73 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 5.0E-28 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 5.0E-28 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 5.0E-28 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 5.0E-28 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 Pfam PF00579 tRNA synthetases class I (W and Y) 6 289 3.5E-83 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS05390 ceb3f66ba2eee5a2e0135e5df031700b 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 334 2.7E-101 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MSG_RS22210 217f037338131c1c3d86240886485312 261 SUPERFAMILY SSF51735 1 260 3.1E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22210 217f037338131c1c3d86240886485312 261 Gene3D G3DSA:3.40.50.720 56 261 1.2E-50 T 29-03-2018 MSG_RS22210 217f037338131c1c3d86240886485312 261 Gene3D G3DSA:3.40.50.720 1 55 5.6E-10 T 29-03-2018 MSG_RS22210 217f037338131c1c3d86240886485312 261 Pfam PF00106 short chain dehydrogenase 7 194 4.5E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0019 T 29-03-2018 MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 3.0E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22210 217f037338131c1c3d86240886485312 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 SUPERFAMILY SSF46785 7 89 7.82E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 SMART SM00418 12 91 2.4E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 2.4E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.4E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.4E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 Pfam PF01022 Bacterial regulatory protein, arsR family 19 65 2.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS18485 494ec0541d3fd164f9eaccd60bdbd146 114 Gene3D G3DSA:1.10.10.10 6 89 9.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11865 599e051c7ae2c1880fedc49774248811 345 Pfam PF03824 High-affinity nickel-transport protein 35 327 4.3E-91 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MSG_RS11865 599e051c7ae2c1880fedc49774248811 345 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 37 322 1.1E-121 T 29-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00412 Epoxide hydrolase signature 274 296 7.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00412 Epoxide hydrolase signature 73 88 7.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00412 Epoxide hydrolase signature 119 132 7.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00412 Epoxide hydrolase signature 53 71 7.1E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 SUPERFAMILY SSF53474 31 296 2.34E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 Pfam PF00561 alpha/beta hydrolase fold 47 170 2.0E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 Hamap MF_01230 Haloalkane dehalogenase [dhmA]. 1 298 54.515 T 29-03-2018 IPR023489 Haloalkane dehalogenase, subfamily 1 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 Gene3D G3DSA:3.40.50.1820 1 300 1.2E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 242 256 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS16070 bb3b0bd8bc4b6be87602d1da97dc3500 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 5.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22380 75d785dc08b7944b4f0011213d62456e 238 Pfam PF06314 Acetoacetate decarboxylase (ADC) 14 225 6.0E-35 T 29-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 MSG_RS22380 75d785dc08b7944b4f0011213d62456e 238 Gene3D G3DSA:2.40.400.10 1 238 2.1E-37 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 MSG_RS22380 75d785dc08b7944b4f0011213d62456e 238 SUPERFAMILY SSF160104 4 236 9.29E-36 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 166 181 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 SUPERFAMILY SSF53623 24 327 5.8E-83 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 PIRSF PIRSF001563 19 478 4.5E-108 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 Gene3D G3DSA:3.90.190.20 331 479 2.4E-26 T 29-03-2018 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 Pfam PF02875 Mur ligase family, glutamate ligase domain 330 407 8.7E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 Pfam PF08245 Mur ligase middle domain 66 303 2.2E-16 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 SUPERFAMILY SSF53244 331 475 6.78E-24 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 TIGRFAM TIGR01499 folC: bifunctional protein FolC 44 472 1.4E-92 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MSG_RS17170 1462a29911fa15a6d3132f086c179908 479 Gene3D G3DSA:3.40.1190.10 13 330 1.0E-79 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 290 1.5E-76 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 SMART SM01130 11 297 6.3E-113 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 295 55.403 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 Pfam PF00701 Dihydrodipicolinate synthetase family 13 295 1.3E-77 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 Gene3D G3DSA:3.20.20.70 6 300 3.9E-88 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 PIRSF PIRSF001365 9 299 2.6E-84 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 2.3E-29 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 2.3E-29 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 2.3E-29 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 2.3E-29 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS08800 d7e2a9843c9b25c6e84a493d5951e485 300 SUPERFAMILY SSF51569 12 298 1.36E-89 T 29-03-2018 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 1.3E-11 T 29-03-2018 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.3E-11 T 29-03-2018 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 1.3E-11 T 29-03-2018 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-11 T 29-03-2018 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 288 1.1E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 SUPERFAMILY SSF51905 3 296 9.26E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 Gene3D G3DSA:3.50.50.60 93 218 5.1E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 Gene3D G3DSA:3.50.50.60 235 325 0.048 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 100 108 4.3E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 4.3E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 4.3E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 4.3E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 4.3E-10 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS20070 3660e21e629cc6bb8fc0aa3532f65ede 394 Gene3D G3DSA:3.50.50.60 1 92 6.3E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 SMART SM00382 636 827 2.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Pfam PF08021 Siderophore-interacting FAD-binding domain 61 113 6.4E-10 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Gene3D G3DSA:1.20.1560.10 272 594 4.3E-33 T 29-03-2018 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 ProSitePatterns PS00211 ABC transporters family signature. 747 761 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Gene3D G3DSA:3.40.50.80 123 259 2.8E-26 T 29-03-2018 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Gene3D G3DSA:3.40.50.300 595 850 2.5E-71 T 29-03-2018 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Pfam PF00005 ABC transporter 628 775 3.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Gene3D G3DSA:2.40.30.10 14 114 9.4E-22 T 29-03-2018 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 SUPERFAMILY SSF63380 13 117 1.98E-9 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 SUPERFAMILY SSF52540 604 844 4.9E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 SUPERFAMILY SSF90123 285 593 3.14E-41 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Pfam PF04954 Siderophore-interacting protein 131 241 2.3E-23 T 29-03-2018 IPR007037 Siderophore-interacting protein MSG_RS18035 61bcf70da2c9e1b750f1523da19f060d 861 Pfam PF00664 ABC transporter transmembrane region 295 452 1.2E-13 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 Gene3D G3DSA:1.10.10.10 90 192 2.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 Pfam PF04542 Sigma-70 region 2 35 97 1.8E-14 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 SUPERFAMILY SSF88659 126 190 5.98E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 SUPERFAMILY SSF88946 9 103 7.06E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 189 6.1E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 Pfam PF04545 Sigma-70, region 4 138 186 3.1E-12 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS03265 9e87a35251b39ecaaff73e079b7f6e02 192 Gene3D G3DSA:1.10.1740.10 2 89 1.5E-18 T 29-03-2018 MSG_RS14185 2bd284b225b40d11df2cf01d107a4548 323 Gene3D G3DSA:3.40.109.10 1 323 1.1E-35 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14185 2bd284b225b40d11df2cf01d107a4548 323 SUPERFAMILY SSF55469 4 93 1.28E-10 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS14185 2bd284b225b40d11df2cf01d107a4548 323 SUPERFAMILY SSF55469 226 321 2.28E-8 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 SUPERFAMILY SSF52402 10 155 2.34E-28 T 29-03-2018 MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 Gene3D G3DSA:3.40.50.620 159 304 9.2E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 Pfam PF00582 Universal stress protein family 162 293 1.6E-23 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 Pfam PF00582 Universal stress protein family 10 148 1.9E-22 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 Gene3D G3DSA:3.40.50.620 2 158 5.0E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 PRINTS PR01438 Universal stress protein signature 271 293 1.3E-15 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 PRINTS PR01438 Universal stress protein signature 159 177 1.3E-15 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 PRINTS PR01438 Universal stress protein signature 253 265 1.3E-15 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13860 429a15b49a3318b73049df2ca3f0c10b 304 SUPERFAMILY SSF52402 161 296 2.09E-29 T 29-03-2018 MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 Pfam PF01327 Polypeptide deformylase 5 163 5.3E-36 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 Gene3D G3DSA:3.90.45.10 1 178 1.3E-50 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 SUPERFAMILY SSF56420 3 188 1.57E-46 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 PIRSF PIRSF004749 1 187 1.0E-34 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 29 164 9.4E-31 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 Hamap MF_00163 Peptide deformylase [def]. 2 177 25.597 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 PRINTS PR01576 Peptide deformylase signature 116 134 3.6E-28 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 PRINTS PR01576 Peptide deformylase signature 104 115 3.6E-28 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 PRINTS PR01576 Peptide deformylase signature 135 164 3.6E-28 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS03125 697a2fccab0f38714b968bdc14cab990 197 PRINTS PR01576 Peptide deformylase signature 38 67 3.6E-28 T 29-03-2018 IPR023635 Peptide deformylase MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 SUPERFAMILY SSF53223 3 121 3.17E-34 T 29-03-2018 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 SUPERFAMILY SSF51735 122 278 9.24E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 Gene3D G3DSA:3.40.50.720 140 263 9.0E-30 T 29-03-2018 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 Gene3D G3DSA:3.40.50.10860 13 139 1.7E-40 T 29-03-2018 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.3E-59 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 3.0E-33 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 9.1E-60 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS05305 ed5b253969876e4107c8ed5c59fec4e1 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 34.299 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 SUPERFAMILY SSF52518 85 500 1.29E-130 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 33 922 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 Gene3D G3DSA:3.40.50.970 505 739 2.2E-65 T 29-03-2018 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 Gene3D G3DSA:3.40.50.920 741 923 3.2E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 SUPERFAMILY SSF52922 737 920 2.27E-52 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 SUPERFAMILY SSF52518 506 733 5.59E-87 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 Gene3D G3DSA:3.40.50.970 84 504 6.7E-84 T 29-03-2018 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 165 331 1.0E-9 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS15715 2494e519f469cf06fc646393121ece9e 929 PIRSF PIRSF000156 25 923 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 Pfam PF00355 Rieske [2Fe-2S] domain 4 66 8.0E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 SUPERFAMILY SSF50022 5 79 7.2E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 Gene3D G3DSA:2.102.10.10 2 79 3.6E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 PRINTS PR00162 Rieske 2Fe-2S subunit signature 20 31 9.1E-9 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 PRINTS PR00162 Rieske 2Fe-2S subunit signature 40 52 9.1E-9 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MSG_RS04725 27919f374ad523c818223ca4556f268e 80 PRINTS PR00162 Rieske 2Fe-2S subunit signature 53 65 9.1E-9 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 Gene3D G3DSA:1.10.357.10 66 199 1.9E-22 T 29-03-2018 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 Gene3D G3DSA:1.10.10.60 5 65 2.8E-18 T 29-03-2018 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.8E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 SUPERFAMILY SSF48498 82 197 1.75E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS22565 f83a8031d3c0072f4d72a762459d8bd0 200 SUPERFAMILY SSF46689 6 87 9.48E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS24085 dc2e7ff3f969e290f216c00ff22c1828 460 SUPERFAMILY SSF56176 16 192 2.29E-37 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS24085 dc2e7ff3f969e290f216c00ff22c1828 460 Pfam PF01565 FAD binding domain 37 160 3.3E-25 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS24085 dc2e7ff3f969e290f216c00ff22c1828 460 Pfam PF04030 D-arabinono-1,4-lactone oxidase 392 456 2.8E-9 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 MSG_RS24085 dc2e7ff3f969e290f216c00ff22c1828 460 Gene3D G3DSA:3.30.465.10 68 195 2.3E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 ProSitePatterns PS00080 Multicopper oxidases signature 2. 527 538 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 ProSitePatterns PS00079 Multicopper oxidases signature 1. 522 542 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Gene3D G3DSA:2.60.40.420 412 543 2.7E-35 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 SUPERFAMILY SSF49503 424 541 1.07E-32 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Pfam PF00394 Multicopper oxidase 248 392 1.8E-23 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 SUPERFAMILY SSF49503 62 185 1.36E-30 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Gene3D G3DSA:2.60.40.420 38 189 4.9E-28 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 SUPERFAMILY SSF49503 187 228 1.46E-33 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 SUPERFAMILY SSF49503 270 408 1.46E-33 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Gene3D G3DSA:2.60.40.420 190 411 2.7E-39 T 29-03-2018 IPR008972 Cupredoxin MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Pfam PF07731 Multicopper oxidase 436 542 2.5E-28 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MSG_RS21430 09fa6327cca5ae0e492bb49fc7066c94 546 Pfam PF07732 Multicopper oxidase 84 184 6.5E-25 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MSG_RS07915 292b6c1ef7ef6770a32a0b650f73e0c4 429 Pfam PF00823 PPE family 5 162 1.1E-60 T 29-03-2018 IPR000030 PPE family MSG_RS07915 292b6c1ef7ef6770a32a0b650f73e0c4 429 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 278 346 4.5E-12 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS07915 292b6c1ef7ef6770a32a0b650f73e0c4 429 SUPERFAMILY SSF140459 5 173 1.67E-59 T 29-03-2018 MSG_RS07915 292b6c1ef7ef6770a32a0b650f73e0c4 429 Gene3D G3DSA:1.10.287.1060 22 106 1.6E-6 T 29-03-2018 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 168 2.6E-60 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.287 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 SUPERFAMILY SSF55200 85 168 3.14E-29 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 Gene3D G3DSA:3.10.20.80 2 78 7.2E-32 T 29-03-2018 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 Gene3D G3DSA:3.30.110.10 79 178 1.7E-31 T 29-03-2018 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 3.0E-32 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 SUPERFAMILY SSF54364 5 78 1.44E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MSG_RS11450 78bf0715659cbd620771a1b204f6d665 202 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 75 1.8E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MSG_RS04730 45ccea4ec18eca590933cacaf6cfd54e 302 SUPERFAMILY SSF56300 43 261 6.27E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS04730 45ccea4ec18eca590933cacaf6cfd54e 302 Gene3D G3DSA:3.60.21.10 31 284 1.1E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS04730 45ccea4ec18eca590933cacaf6cfd54e 302 Pfam PF00149 Calcineurin-like phosphoesterase 45 236 7.9E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MSG_RS12560 c99ba62e9edb48dd15c1d09a94ef5097 354 SUPERFAMILY SSF52518 32 349 8.3E-86 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS12560 c99ba62e9edb48dd15c1d09a94ef5097 354 Pfam PF00676 Dehydrogenase E1 component 43 338 4.9E-69 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MSG_RS12560 c99ba62e9edb48dd15c1d09a94ef5097 354 Gene3D G3DSA:3.40.50.970 12 350 4.5E-77 T 29-03-2018 MSG_RS09305 f85347d07a8920d53a4985fe7eda8bb0 382 SUPERFAMILY SSF56349 82 368 3.83E-51 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MSG_RS09305 f85347d07a8920d53a4985fe7eda8bb0 382 Gene3D G3DSA:1.10.150.130 74 190 1.5E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MSG_RS09305 f85347d07a8920d53a4985fe7eda8bb0 382 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 82 138 5.2E-7 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MSG_RS09305 f85347d07a8920d53a4985fe7eda8bb0 382 Pfam PF00589 Phage integrase family 203 364 1.3E-19 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS09305 f85347d07a8920d53a4985fe7eda8bb0 382 Gene3D G3DSA:1.10.443.10 191 367 2.7E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 SUPERFAMILY SSF55920 136 366 2.22E-70 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 SUPERFAMILY SSF53092 5 134 1.13E-22 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 Gene3D G3DSA:3.90.230.10 120 367 4.9E-76 T 29-03-2018 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 Pfam PF00557 Metallopeptidase family M24 144 347 7.0E-62 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 136 3.7E-23 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 1.5E-5 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 1.5E-5 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 1.5E-5 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS09935 7a47eafc686b93bce9b6b340385afa6b 367 Gene3D G3DSA:3.40.350.10 1 119 7.6E-29 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 Pfam PF03176 MMPL family 452 680 1.2E-43 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 Pfam PF03176 MMPL family 58 373 1.1E-57 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 SUPERFAMILY SSF82866 489 680 4.05E-26 T 29-03-2018 MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 Gene3D G3DSA:1.20.1640.10 427 677 3.1E-22 T 29-03-2018 MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 Gene3D G3DSA:1.20.1640.10 133 342 4.5E-32 T 29-03-2018 MSG_RS07535 ff71e0819221dbb619952870a85ade8c 703 SUPERFAMILY SSF82866 122 345 9.29E-32 T 29-03-2018 MSG_RS23625 a1cb00b99eb797d45e560b3668966203 300 Gene3D G3DSA:3.20.20.140 23 300 3.1E-31 T 29-03-2018 MSG_RS23625 a1cb00b99eb797d45e560b3668966203 300 SUPERFAMILY SSF51556 25 295 3.93E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS23625 a1cb00b99eb797d45e560b3668966203 300 Pfam PF04909 Amidohydrolase 28 294 3.5E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 1.6E-88 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 Gene3D G3DSA:3.40.1010.10 1 121 3.1E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 1.1E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 Gene3D G3DSA:3.30.950.10 122 239 9.2E-24 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 SUPERFAMILY SSF53790 2 232 4.06E-63 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14635 d4d72716d2a46cb3a1a7befea110f9e9 251 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.7E-10 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.7E-10 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 3.7E-10 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.7E-10 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 286 1.4E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 Gene3D G3DSA:3.40.50.720 1 131 5.2E-8 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 Gene3D G3DSA:3.40.50.720 136 335 6.8E-22 T 29-03-2018 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 SUPERFAMILY SSF51905 236 298 1.41E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 SUPERFAMILY SSF51905 4 151 1.41E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 SUPERFAMILY SSF51905 142 295 8.64E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 1.4E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.4E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.4E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS12100 db8dd361a9aa61be9e4c331787e50392 383 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 1.4E-8 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 Gene3D G3DSA:1.20.140.10 214 375 1.2E-31 T 29-03-2018 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 SUPERFAMILY SSF47203 237 372 1.94E-33 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 368 7.5E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 Gene3D G3DSA:2.40.110.10 123 213 3.2E-13 T 29-03-2018 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 Gene3D G3DSA:1.10.540.10 4 122 1.8E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 98 1.8E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17785 f09616197e7efcec52b909161e1d1d26 380 SUPERFAMILY SSF56645 6 222 1.44E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 8.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 8.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 8.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00412 Epoxide hydrolase signature 37 55 2.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00412 Epoxide hydrolase signature 57 72 2.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00412 Epoxide hydrolase signature 298 320 2.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 PRINTS PR00412 Epoxide hydrolase signature 117 130 2.1E-23 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 Pfam PF00561 alpha/beta hydrolase fold 31 309 4.2E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 SUPERFAMILY SSF53474 218 322 1.85E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 SUPERFAMILY SSF53474 9 186 1.85E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13775 4f93c8a3dcb409bce733abafebe594df 341 Gene3D G3DSA:3.40.50.1820 8 331 2.0E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00160 4798e3a6d3952d6006d4cdb9cf8718b9 453 SUPERFAMILY SSF140459 2 171 1.02E-62 T 29-03-2018 MSG_RS00160 4798e3a6d3952d6006d4cdb9cf8718b9 453 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 386 4.4E-8 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS00160 4798e3a6d3952d6006d4cdb9cf8718b9 453 Pfam PF00823 PPE family 5 161 1.3E-62 T 29-03-2018 IPR000030 PPE family MSG_RS00160 4798e3a6d3952d6006d4cdb9cf8718b9 453 Gene3D G3DSA:1.10.287.1060 22 105 2.7E-8 T 29-03-2018 MSG_RS00160 4798e3a6d3952d6006d4cdb9cf8718b9 453 Pfam PF09851 Short C-terminal domain 423 449 8.2E-9 T 29-03-2018 IPR018649 SHOCT domain MSG_RS15505 58f759ae659b7ce1e151ff345cc8894c 518 SUPERFAMILY SSF53474 101 153 1.01E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15505 58f759ae659b7ce1e151ff345cc8894c 518 SUPERFAMILY SSF53474 199 482 1.01E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15505 58f759ae659b7ce1e151ff345cc8894c 518 Gene3D G3DSA:3.40.50.1820 48 506 3.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15505 58f759ae659b7ce1e151ff345cc8894c 518 Pfam PF00561 alpha/beta hydrolase fold 104 493 6.3E-56 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS05235 68080fba4c393c0514f3871ea00d577b 138 Gene3D G3DSA:2.30.110.10 2 137 8.2E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS05235 68080fba4c393c0514f3871ea00d577b 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 86 4.4E-12 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS05235 68080fba4c393c0514f3871ea00d577b 138 TIGRFAM TIGR03667 Rv3369: PPOX class probable F420-dependent enzyme, Rv3369 family 4 132 5.5E-47 T 29-03-2018 IPR019966 F420-dependent enzyme, PPOX class, family Rv3369, probable MSG_RS05235 68080fba4c393c0514f3871ea00d577b 138 SUPERFAMILY SSF50475 4 134 2.06E-22 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS00680 e6827ade2a88f6aa5376721875ce044e 461 Gene3D G3DSA:3.20.20.30 1 460 8.8E-91 T 29-03-2018 MSG_RS00680 e6827ade2a88f6aa5376721875ce044e 461 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 18 441 4.4E-125 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00680 e6827ade2a88f6aa5376721875ce044e 461 SUPERFAMILY SSF51679 6 445 3.79E-106 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00680 e6827ade2a88f6aa5376721875ce044e 461 PIRSF PIRSF000337 2 455 4.0E-148 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00680 e6827ade2a88f6aa5376721875ce044e 461 Pfam PF00296 Luciferase-like monooxygenase 28 397 5.2E-51 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Pfam PF02785 Biotin carboxylase C-terminal domain 342 452 1.3E-35 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 330 2.6E-80 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Gene3D G3DSA:2.40.50.100 524 599 2.1E-15 T 29-03-2018 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 SUPERFAMILY SSF51246 336 456 7.32E-38 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 SUPERFAMILY SSF51230 527 598 5.89E-19 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Gene3D G3DSA:3.30.470.20 217 455 5.7E-93 T 29-03-2018 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 555 572 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 117 3.2E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Gene3D G3DSA:3.30.1490.20 131 216 1.1E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 SUPERFAMILY SSF56059 90 337 2.47E-58 T 29-03-2018 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 293 300 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 SMART SM00878 342 452 1.2E-57 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 160 174 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Pfam PF00364 Biotin-requiring enzyme 533 598 5.2E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 Gene3D G3DSA:3.40.50.20 8 130 2.2E-48 T 29-03-2018 MSG_RS05675 fb782cefc9007298b71e70ad133466d9 599 SUPERFAMILY SSF52440 7 120 4.32E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS15245 ca538ccbb0998f8f8aca869bbb8501bb 419 Gene3D G3DSA:3.40.50.300 2 340 1.0E-47 T 29-03-2018 MSG_RS15245 ca538ccbb0998f8f8aca869bbb8501bb 419 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 9 320 7.8E-41 T 29-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 MSG_RS15245 ca538ccbb0998f8f8aca869bbb8501bb 419 Pfam PF02374 Anion-transporting ATPase 6 320 5.9E-43 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MSG_RS15245 ca538ccbb0998f8f8aca869bbb8501bb 419 SUPERFAMILY SSF52540 5 307 6.23E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24000 59f75e448c5f0b275382fe4a3d7c545e 416 Gene3D G3DSA:3.40.710.10 19 415 9.0E-67 T 29-03-2018 MSG_RS24000 59f75e448c5f0b275382fe4a3d7c545e 416 Pfam PF00144 Beta-lactamase 46 405 4.2E-63 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS24000 59f75e448c5f0b275382fe4a3d7c545e 416 SUPERFAMILY SSF56601 37 401 2.93E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 Gene3D G3DSA:3.40.47.10 237 392 4.9E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 Pfam PF00108 Thiolase, N-terminal domain 5 229 2.4E-18 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 SUPERFAMILY SSF53901 259 382 2.96E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 Gene3D G3DSA:3.40.47.10 1 236 2.0E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 PIRSF PIRSF000429 2 392 3.0E-67 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 Pfam PF02803 Thiolase, C-terminal domain 270 374 5.3E-10 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 SUPERFAMILY SSF53901 5 236 2.44E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08605 fc15bf5e983aa18bb0e3f2d391237639 396 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 Gene3D G3DSA:3.30.70.20 1 64 1.6E-7 T 29-03-2018 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 SUPERFAMILY SSF54862 2 60 3.74E-12 T 29-03-2018 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.2E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.2E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 6.2E-6 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21265 50c320ede5e363c8c3e8552f9879eff0 66 Pfam PF13459 4Fe-4S single cluster domain 3 59 9.6E-16 T 29-03-2018 MSG_RS14995 2bc6bcea687c115a17204ba59d31def5 218 Gene3D G3DSA:1.10.10.10 9 208 0.0015 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13015 5ab791db0ad238a55be970c42b987347 99 Pfam PF04226 Transglycosylase associated protein 50 98 8.0E-13 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF52777 1265 1523 2.67E-47 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:2.30.38.10 1867 1949 8.1E-25 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF52777 42 205 5.11E-32 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00501 AMP-binding enzyme 1564 1956 2.4E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00501 AMP-binding enzyme 495 874 8.0E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF47336 2063 2133 3.4E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.40.50.980 1548 1701 2.1E-37 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2093 2108 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SMART SM00823 Phosphopantetheine attachment site 2069 2137 2.7E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SMART SM00823 Phosphopantetheine attachment site 985 1054 2.3E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1701 1712 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:2.30.38.10 784 864 1.0E-23 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF52777 1076 1251 1.56E-45 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:1.10.1200.10 2075 2139 7.9E-22 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF47336 977 1086 2.75E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF52777 218 458 1.56E-41 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00550 Phosphopantetheine attachment site 2071 2133 3.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00550 Phosphopantetheine attachment site 987 1050 3.5E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.40.50.980 486 624 1.9E-42 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF56801 455 997 2.35E-153 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.30.300.30 869 990 5.2E-35 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.30.300.30 1951 2074 1.1E-26 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.40.50.980 1702 1858 6.5E-33 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00668 Condensation domain 39 471 3.5E-55 T 29-03-2018 IPR001242 Condensation domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF00668 Condensation domain 1074 1531 2.0E-72 T 29-03-2018 IPR001242 Condensation domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF13193 AMP-binding enzyme C-terminal domain 1964 2044 1.6E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Pfam PF13193 AMP-binding enzyme C-terminal domain 882 960 1.6E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.40.50.980 625 783 3.2E-34 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.30.559.10 18 223 7.8E-29 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:3.30.559.10 1071 1250 1.4E-38 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 Gene3D G3DSA:1.10.1200.10 991 1070 2.6E-21 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 SUPERFAMILY SSF56801 1512 2081 6.41E-132 T 29-03-2018 MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1577 1979 9.3E-110 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 515 898 2.3E-123 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1009 1024 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS16775 1b1e2d80df95a90f2730531d88dde546 2182 ProSitePatterns PS00455 Putative AMP-binding domain signature. 619 630 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS14260 b5870190d8b328ad08606cbe95f20001 346 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 148 278 2.1E-6 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS14260 b5870190d8b328ad08606cbe95f20001 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 7.3E-81 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14260 b5870190d8b328ad08606cbe95f20001 346 Pfam PF02470 MlaD protein 37 112 3.1E-16 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 Gene3D G3DSA:1.10.10.60 1 72 1.2E-13 T 29-03-2018 MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 SUPERFAMILY SSF46689 15 88 2.59E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 SUPERFAMILY SSF48498 94 209 6.82E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 8.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17130 a6d4a2e692460b72f9dbe898f087e8c3 214 Gene3D G3DSA:1.10.357.10 73 212 3.6E-17 T 29-03-2018 MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 Gene3D G3DSA:3.40.50.300 23 270 1.5E-13 T 29-03-2018 MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 Gene3D G3DSA:3.40.50.300 315 527 2.6E-4 T 29-03-2018 MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 SUPERFAMILY SSF52540 322 514 1.91E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 11 574 4.5E-198 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 Pfam PF01580 FtsK/SpoIIIE family 56 286 2.3E-44 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 Pfam PF01580 FtsK/SpoIIIE family 363 460 8.5E-10 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 SMART SM00382 76 254 0.44 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 SMART SM00382 368 542 0.75 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24495 85f42484d85955ed99ef3571e365be47 591 SUPERFAMILY SSF52540 27 258 2.88E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 Pfam PF00293 NUDIX domain 79 177 9.6E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 PRINTS PR00502 NUDIX hydrolase family signature 111 126 2.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 PRINTS PR00502 NUDIX hydrolase family signature 97 111 2.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 ProSitePatterns PS00893 Nudix box signature. 102 123 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 Gene3D G3DSA:3.90.79.10 3 220 3.2E-34 T 29-03-2018 MSG_RS00590 4d67c03e7451f13516b3acc05f75a637 239 SUPERFAMILY SSF55811 72 180 2.57E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS07560 00d86d371d99dad1d41c1ddac575aa4b 187 Gene3D G3DSA:1.10.10.10 1 157 4.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07560 00d86d371d99dad1d41c1ddac575aa4b 187 SMART SM00347 37 141 5.9E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS07560 00d86d371d99dad1d41c1ddac575aa4b 187 SUPERFAMILY SSF46785 11 159 1.85E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07560 00d86d371d99dad1d41c1ddac575aa4b 187 Pfam PF12802 MarR family 46 104 1.1E-12 T 29-03-2018 MSG_RS20000 84279f92e95b0f050701e9353b1f184d 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 238 9.5E-46 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS20000 84279f92e95b0f050701e9353b1f184d 312 Gene3D G3DSA:3.40.50.720 2 188 6.8E-26 T 29-03-2018 MSG_RS20000 84279f92e95b0f050701e9353b1f184d 312 Gene3D G3DSA:3.90.25.10 189 309 8.0E-16 T 29-03-2018 MSG_RS20000 84279f92e95b0f050701e9353b1f184d 312 SUPERFAMILY SSF51735 1 293 2.19E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 PIRSF PIRSF000429 1 402 6.5E-127 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 Gene3D G3DSA:3.40.47.10 1 271 7.6E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 SUPERFAMILY SSF53901 276 400 4.47E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 Pfam PF00108 Thiolase, N-terminal domain 5 266 6.7E-66 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 Gene3D G3DSA:3.40.47.10 272 398 1.7E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 399 7.1E-130 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 Pfam PF02803 Thiolase, C-terminal domain 276 400 1.5E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS18000 af4e57f3adef8900e815901731b2a407 404 SUPERFAMILY SSF53901 4 275 1.77E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 621 41.517 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Pfam PF02779 Transketolase, pyrimidine binding domain 315 476 6.9E-37 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Gene3D G3DSA:3.40.50.920 494 622 3.1E-28 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 SUPERFAMILY SSF52518 292 476 3.72E-54 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 SUPERFAMILY SSF52518 18 193 3.04E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 SUPERFAMILY SSF52518 238 361 3.04E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 620 6.0E-188 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 278 8.1E-108 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 SUPERFAMILY SSF52922 501 620 5.76E-23 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 SMART SM00861 314 478 9.8E-55 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Pfam PF02780 Transketolase, C-terminal domain 500 612 2.8E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Gene3D G3DSA:3.40.50.970 1 309 4.2E-75 T 29-03-2018 MSG_RS09115 c266a0d143d8aa9de2f4fdef0b3d27df 637 Gene3D G3DSA:3.40.50.970 310 480 1.4E-38 T 29-03-2018 MSG_RS02350 041cb4b024d0221718f19a96119f6969 301 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 4.6E-60 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS02350 041cb4b024d0221718f19a96119f6969 301 SUPERFAMILY SSF53335 14 284 3.71E-75 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS02350 041cb4b024d0221718f19a96119f6969 301 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 278 4.1E-87 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS02350 041cb4b024d0221718f19a96119f6969 301 Gene3D G3DSA:3.40.50.150 2 273 2.1E-53 T 29-03-2018 MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 PIRSF PIRSF004682 1 176 2.3E-48 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 Pfam PF13242 HAD-hyrolase-like 105 160 8.8E-13 T 29-03-2018 MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 Gene3D G3DSA:3.40.50.1000 5 176 2.2E-30 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 150 2.8E-28 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 SUPERFAMILY SSF56784 4 174 4.55E-41 T 29-03-2018 IPR023214 HAD-like domain MSG_RS20125 ff9b62a0f2b4059fdd71af04d9a82621 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 8 148 1.0E-34 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MSG_RS02960 71e8c1cfa5d4ee63c41131723c9937da 250 Gene3D G3DSA:3.60.15.10 3 249 2.2E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS02960 71e8c1cfa5d4ee63c41131723c9937da 250 Pfam PF00753 Metallo-beta-lactamase superfamily 21 228 6.0E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS02960 71e8c1cfa5d4ee63c41131723c9937da 250 SMART SM00849 21 228 8.7E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS02960 71e8c1cfa5d4ee63c41131723c9937da 250 SUPERFAMILY SSF56281 7 236 1.04E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 Gene3D G3DSA:1.20.59.10 39 117 2.3E-15 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 SMART SM00830 31 111 5.9E-13 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 PIRSF PIRSF026640 6 193 2.9E-60 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 Pfam PF01817 Chorismate mutase type II 40 108 8.7E-8 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 SUPERFAMILY SSF48600 39 192 1.92E-39 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS13205 5746c70f60dd802528448f669636c8bb 193 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 36 147 5.1E-33 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS09570 dd8b29523f8cc5c9b10ed14cfc56e942 207 Gene3D G3DSA:3.10.129.10 44 206 2.4E-21 T 29-03-2018 MSG_RS09570 dd8b29523f8cc5c9b10ed14cfc56e942 207 SUPERFAMILY SSF54637 12 201 1.59E-38 T 29-03-2018 IPR029069 HotDog domain MSG_RS09570 dd8b29523f8cc5c9b10ed14cfc56e942 207 Pfam PF03061 Thioesterase superfamily 117 192 4.6E-7 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS22915 eb31db85eda81a3dff569bd996a5e64f 350 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 13 349 7.9E-114 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 MSG_RS22915 eb31db85eda81a3dff569bd996a5e64f 350 Pfam PF10103 Zincin-like metallopeptidase 13 346 3.5E-101 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 MSG_RS22915 eb31db85eda81a3dff569bd996a5e64f 350 SUPERFAMILY SSF55486 13 349 1.17E-95 T 29-03-2018 MSG_RS22915 eb31db85eda81a3dff569bd996a5e64f 350 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 13 349 2.6E-125 T 29-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated MSG_RS20805 9fc4fd0853fc65790d09b1d2157816c1 141 Gene3D G3DSA:3.90.1170.40 3 141 2.4E-42 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20805 9fc4fd0853fc65790d09b1d2157816c1 141 Pfam PF02391 MoaE protein 9 121 4.2E-32 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20805 9fc4fd0853fc65790d09b1d2157816c1 141 SUPERFAMILY SSF54690 8 139 4.32E-37 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS12840 bf5dc7bf9c702a69e9083951ffc315d7 210 Gene3D G3DSA:1.10.1660.10 50 126 2.5E-14 T 29-03-2018 MSG_RS12840 bf5dc7bf9c702a69e9083951ffc315d7 210 SMART SM00422 50 122 2.3E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS12840 bf5dc7bf9c702a69e9083951ffc315d7 210 Pfam PF13411 MerR HTH family regulatory protein 54 119 7.2E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS12840 bf5dc7bf9c702a69e9083951ffc315d7 210 SUPERFAMILY SSF46955 55 137 7.33E-14 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS18660 f7cd65f28fe2c5cc039ecfe8ac67353f 304 Pfam PF10118 Predicted metal-dependent hydrolase 6 197 1.7E-40 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 MSG_RS18660 f7cd65f28fe2c5cc039ecfe8ac67353f 304 Gene3D G3DSA:1.20.1260.10 6 88 6.3E-6 T 29-03-2018 IPR012347 Ferritin-related MSG_RS22415 2e2b324156eb8482d86ec3b24616211f 395 Gene3D G3DSA:2.102.10.10 18 130 1.2E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS22415 2e2b324156eb8482d86ec3b24616211f 395 SUPERFAMILY SSF55961 124 345 2.2E-31 T 29-03-2018 MSG_RS22415 2e2b324156eb8482d86ec3b24616211f 395 SUPERFAMILY SSF50022 20 133 2.36E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS22415 2e2b324156eb8482d86ec3b24616211f 395 Pfam PF00355 Rieske [2Fe-2S] domain 26 109 1.9E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS22415 2e2b324156eb8482d86ec3b24616211f 395 Gene3D G3DSA:3.90.380.10 131 347 5.4E-31 T 29-03-2018 MSG_RS10805 b4e14f6d1ce7c63d4fc35e02879eac5f 414 Gene3D G3DSA:3.40.50.2000 1 249 3.0E-30 T 29-03-2018 MSG_RS10805 b4e14f6d1ce7c63d4fc35e02879eac5f 414 SUPERFAMILY SSF53756 3 410 1.22E-81 T 29-03-2018 MSG_RS10805 b4e14f6d1ce7c63d4fc35e02879eac5f 414 Gene3D G3DSA:3.40.50.2000 250 392 2.8E-24 T 29-03-2018 MSG_RS10805 b4e14f6d1ce7c63d4fc35e02879eac5f 414 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 81 1.0E-6 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS20760 9fd1782dbf8b38e43292598d3f612b64 319 Pfam PF11228 Protein of unknown function (DUF3027) 45 234 6.2E-79 T 29-03-2018 IPR021391 Protein of unknown function DUF3027 MSG_RS12810 2828a2799e787df6e70bf26a2872a97a 110 PIRSF PIRSF018579 1 110 1.6E-46 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 MSG_RS12810 2828a2799e787df6e70bf26a2872a97a 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 7.3E-33 T 29-03-2018 IPR009709 Protein of unknown function DUF1290 MSG_RS11775 a48bb7c77914d76ba2e6809aed52a86b 311 Pfam PF00106 short chain dehydrogenase 8 148 6.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11775 a48bb7c77914d76ba2e6809aed52a86b 311 SUPERFAMILY SSF51735 4 234 2.34E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11775 a48bb7c77914d76ba2e6809aed52a86b 311 Gene3D G3DSA:3.40.50.720 2 232 2.8E-30 T 29-03-2018 MSG_RS15235 4352738aefcd06c5fa77f71ce5284564 248 Gene3D G3DSA:3.40.1130.10 1 230 9.1E-58 T 29-03-2018 MSG_RS15235 4352738aefcd06c5fa77f71ce5284564 248 SUPERFAMILY SSF69593 3 217 7.19E-55 T 29-03-2018 MSG_RS15235 4352738aefcd06c5fa77f71ce5284564 248 Pfam PF01553 Acyltransferase 21 151 1.1E-29 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS15235 4352738aefcd06c5fa77f71ce5284564 248 SMART SM00563 35 154 2.1E-38 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 Gene3D G3DSA:3.40.50.1260 193 395 1.5E-74 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 407 38.711 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PIRSF PIRSF000724 2 412 1.0E-124 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 Pfam PF00162 Phosphoglycerate kinase 17 397 1.6E-133 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 Gene3D G3DSA:3.40.50.1260 6 192 1.7E-55 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 SUPERFAMILY SSF53748 16 406 4.36E-133 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 21 31 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 181 203 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 204 223 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 151 173 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 116 131 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 359 370 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 16 32 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 383 400 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 38 60 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS10455 0a6f1b81a52796962f7daf2b5a500821 415 PRINTS PR00477 Phosphoglycerate kinase family signature 323 348 7.7E-74 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 Gene3D G3DSA:3.40.605.10 2 268 9.5E-82 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 Pfam PF00171 Aldehyde dehydrogenase family 13 476 1.4E-156 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 Gene3D G3DSA:3.40.309.10 269 463 4.8E-72 T 29-03-2018 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 SUPERFAMILY SSF53720 4 478 4.45E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS23600 78f546d6ae13d4c7631d8ce7131eb349 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS13985 220b0390b91489ba1a64bb367d52b2db 146 Gene3D G3DSA:2.30.110.10 1 134 8.4E-18 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13985 220b0390b91489ba1a64bb367d52b2db 146 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 131 5.6E-25 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MSG_RS13985 220b0390b91489ba1a64bb367d52b2db 146 SUPERFAMILY SSF50475 10 133 1.0E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS03270 3dfad098f0b389e7e24b0ddb5e420787 576 Pfam PF00578 AhpC/TSA family 294 405 3.7E-11 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS03270 3dfad098f0b389e7e24b0ddb5e420787 576 Gene3D G3DSA:3.40.30.10 269 448 4.6E-23 T 29-03-2018 MSG_RS03270 3dfad098f0b389e7e24b0ddb5e420787 576 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 209 1.1E-18 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MSG_RS03270 3dfad098f0b389e7e24b0ddb5e420787 576 Gene3D G3DSA:2.60.120.260 449 575 2.8E-33 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS03270 3dfad098f0b389e7e24b0ddb5e420787 576 SUPERFAMILY SSF52833 294 424 1.66E-31 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS08870 264fe14d099e04715b80db61173c9aec 388 Gene3D G3DSA:3.40.50.2000 1 213 1.0E-24 T 29-03-2018 MSG_RS08870 264fe14d099e04715b80db61173c9aec 388 Gene3D G3DSA:3.40.50.2000 214 370 6.4E-21 T 29-03-2018 MSG_RS08870 264fe14d099e04715b80db61173c9aec 388 SUPERFAMILY SSF53756 1 369 2.86E-57 T 29-03-2018 MSG_RS08870 264fe14d099e04715b80db61173c9aec 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 286 367 1.5E-5 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MSG_RS22660 1855ead17993b9a7e0e33a84308c616e 219 SUPERFAMILY SSF46689 36 98 4.24E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS22660 1855ead17993b9a7e0e33a84308c616e 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 86 9.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22660 1855ead17993b9a7e0e33a84308c616e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 6.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22660 1855ead17993b9a7e0e33a84308c616e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 6.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS22660 1855ead17993b9a7e0e33a84308c616e 219 Gene3D G3DSA:1.10.357.10 25 219 1.1E-37 T 29-03-2018 MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 272 3.6E-106 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 9.1E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 271 3.9E-50 T 29-03-2018 MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 SUPERFAMILY SSF51735 6 271 3.49E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 Gene3D G3DSA:3.40.50.720 1 273 4.8E-65 T 29-03-2018 MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18015 14f7124b97719c6eaa6b0e4910518e9a 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.3E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 SUPERFAMILY SSF53187 8 85 1.05E-92 T 29-03-2018 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 SUPERFAMILY SSF53187 211 425 1.05E-92 T 29-03-2018 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 5 427 54.253 T 29-03-2018 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 Gene3D G3DSA:3.40.630.10 4 129 2.9E-29 T 29-03-2018 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 Gene3D G3DSA:3.40.630.10 182 429 2.1E-76 T 29-03-2018 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 15 425 7.3E-142 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 SUPERFAMILY SSF101821 86 210 5.04E-24 T 29-03-2018 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 74 90 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 107 127 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 303 319 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 392 407 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 260 278 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS21825 64538f8d116ccf531d1939acb265d115 429 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 145 162 8.1E-51 T 29-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MSG_RS13880 1befe6905b70d9641ebcf3a2778aecb0 186 Pfam PF13302 Acetyltransferase (GNAT) domain 20 153 2.5E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS13880 1befe6905b70d9641ebcf3a2778aecb0 186 Gene3D G3DSA:3.40.630.30 11 180 2.8E-21 T 29-03-2018 MSG_RS13880 1befe6905b70d9641ebcf3a2778aecb0 186 SUPERFAMILY SSF55729 16 157 3.14E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS05795 71aa82487849fb0b58c3f2b979995c89 491 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 91 260 1.9E-33 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS05795 71aa82487849fb0b58c3f2b979995c89 491 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 362 445 1.0E-11 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS05795 71aa82487849fb0b58c3f2b979995c89 491 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 91 260 6.6E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS04660 a487b39ab6075cd2f3e82fb74c19b3cf 218 SUPERFAMILY SSF53639 11 212 6.67E-58 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS04660 a487b39ab6075cd2f3e82fb74c19b3cf 218 Gene3D G3DSA:3.40.225.10 2 212 1.5E-53 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS04660 a487b39ab6075cd2f3e82fb74c19b3cf 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 186 1.4E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS04660 a487b39ab6075cd2f3e82fb74c19b3cf 218 SMART SM01007 9 187 7.8E-56 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS23765 aa021251889f83c15c13481c0840a87e 376 SUPERFAMILY SSF51445 44 356 1.52E-59 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS23765 aa021251889f83c15c13481c0840a87e 376 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 68 321 2.1E-7 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 MSG_RS23765 aa021251889f83c15c13481c0840a87e 376 Gene3D G3DSA:3.20.20.80 42 355 6.4E-34 T 29-03-2018 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 SUPERFAMILY SSF52540 314 507 6.28E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 SMART SM00382 30 233 2.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 SMART SM00382 346 516 6.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 2.6E-271 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 Pfam PF12848 ABC transporter 227 303 2.6E-13 T 29-03-2018 IPR032781 ABC-transporter extension domain MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 Pfam PF00005 ABC transporter 338 471 8.9E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 Pfam PF00005 ABC transporter 21 188 1.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 SUPERFAMILY SSF52540 8 241 7.16E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 Gene3D G3DSA:3.40.50.300 286 549 1.7E-50 T 29-03-2018 MSG_RS17320 7700a24a65595c43eacc86580248d0de 558 Gene3D G3DSA:3.40.50.300 6 285 4.8E-57 T 29-03-2018 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 SUPERFAMILY SSF53474 4 368 5.18E-87 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 Gene3D G3DSA:3.40.50.1820 1 376 1.8E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 PRINTS PR00412 Epoxide hydrolase signature 164 177 6.2E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 PRINTS PR00412 Epoxide hydrolase signature 347 369 6.2E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 PRINTS PR00412 Epoxide hydrolase signature 316 332 6.2E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 PRINTS PR00412 Epoxide hydrolase signature 100 118 6.2E-13 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 PIRSF PIRSF001112 3 376 3.5E-103 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 MSG_RS22125 5e03327b48c358b81423dca508fcf066 379 Pfam PF06441 Epoxide hydrolase N terminus 5 109 7.1E-28 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 MSG_RS14290 230543c2089fb46ca0cae2eb2f700f72 406 SUPERFAMILY SSF103473 22 398 1.07E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS14290 230543c2089fb46ca0cae2eb2f700f72 406 Pfam PF07690 Major Facilitator Superfamily 32 214 5.3E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS14290 230543c2089fb46ca0cae2eb2f700f72 406 Pfam PF07690 Major Facilitator Superfamily 236 396 4.0E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS14290 230543c2089fb46ca0cae2eb2f700f72 406 Gene3D G3DSA:1.20.1250.20 16 219 1.4E-26 T 29-03-2018 MSG_RS14290 230543c2089fb46ca0cae2eb2f700f72 406 Gene3D G3DSA:1.20.1250.20 225 403 4.3E-21 T 29-03-2018 MSG_RS02050 07977d2d5e6bf1597fec5f8936d05e39 384 Gene3D G3DSA:3.40.50.2000 192 357 4.3E-36 T 29-03-2018 MSG_RS02050 07977d2d5e6bf1597fec5f8936d05e39 384 Gene3D G3DSA:3.40.50.2000 6 191 2.1E-7 T 29-03-2018 MSG_RS02050 07977d2d5e6bf1597fec5f8936d05e39 384 Pfam PF13439 Glycosyltransferase Family 4 21 186 3.9E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS02050 07977d2d5e6bf1597fec5f8936d05e39 384 Pfam PF00534 Glycosyl transferases group 1 200 353 2.4E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS02050 07977d2d5e6bf1597fec5f8936d05e39 384 SUPERFAMILY SSF53756 7 371 4.19E-66 T 29-03-2018 MSG_RS16985 0e21fc83ce166a72a5e8fb5fc4b5ed96 352 SUPERFAMILY SSF51735 9 146 2.95E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16985 0e21fc83ce166a72a5e8fb5fc4b5ed96 352 Gene3D G3DSA:3.40.50.720 3 135 4.0E-17 T 29-03-2018 MSG_RS06790 d0669917c2dc2c9fd0918e993d0af993 330 Gene3D G3DSA:3.90.1200.10 124 310 1.3E-24 T 29-03-2018 MSG_RS06790 d0669917c2dc2c9fd0918e993d0af993 330 Pfam PF01636 Phosphotransferase enzyme family 30 267 1.0E-26 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS06790 d0669917c2dc2c9fd0918e993d0af993 330 Gene3D G3DSA:3.30.200.20 8 108 1.4E-10 T 29-03-2018 MSG_RS06790 d0669917c2dc2c9fd0918e993d0af993 330 SUPERFAMILY SSF56112 11 324 8.25E-49 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 Pfam PF00027 Cyclic nucleotide-binding domain 353 438 5.6E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 PIRSF PIRSF026673 12 476 1.3E-110 T 29-03-2018 IPR016846 Predicted ion channel, cNMP-binding MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 Pfam PF00924 Mechanosensitive ion channel 117 280 9.5E-32 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 SUPERFAMILY SSF50182 160 224 4.25E-10 T 29-03-2018 IPR010920 LSM domain MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 SUPERFAMILY SSF51206 338 456 1.96E-21 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 Gene3D G3DSA:2.60.120.10 328 462 3.4E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 SMART SM00100 334 451 9.3E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS17040 d6038558fbf81a50acf5e72e5f62b54c 480 Gene3D G3DSA:2.30.30.60 175 225 1.8E-7 T 29-03-2018 MSG_RS05875 6d32807e53bdd60b88d21013043463ea 402 Pfam PF00487 Fatty acid desaturase 126 357 8.1E-34 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MSG_RS00055 e053df14a825544b6f7f7cafa1cc041c 249 Pfam PF00975 Thioesterase domain 23 246 2.0E-40 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MSG_RS00055 e053df14a825544b6f7f7cafa1cc041c 249 SMART SM00824 Thioesterase 23 248 4.0E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 MSG_RS00055 e053df14a825544b6f7f7cafa1cc041c 249 Gene3D G3DSA:3.40.50.1820 2 248 3.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00055 e053df14a825544b6f7f7cafa1cc041c 249 SUPERFAMILY SSF53474 6 248 1.26E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09600 a023f3d41e109c2e3eddedf28076c720 347 ProSitePatterns PS00893 Nudix box signature. 219 240 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS09600 a023f3d41e109c2e3eddedf28076c720 347 Pfam PF00293 NUDIX domain 180 317 9.2E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS09600 a023f3d41e109c2e3eddedf28076c720 347 SUPERFAMILY SSF55811 169 308 1.35E-18 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS09600 a023f3d41e109c2e3eddedf28076c720 347 Gene3D G3DSA:3.90.79.10 172 339 4.0E-20 T 29-03-2018 MSG_RS09600 a023f3d41e109c2e3eddedf28076c720 347 Gene3D G3DSA:1.20.1440.20 17 171 2.0E-33 T 29-03-2018 MSG_RS03795 6a67d40bbca742bd30ff0c1bbaeafcbd 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 111 4.5E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS03795 6a67d40bbca742bd30ff0c1bbaeafcbd 135 SUPERFAMILY SSF54593 9 115 8.73E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS03795 6a67d40bbca742bd30ff0c1bbaeafcbd 135 Gene3D G3DSA:3.10.180.10 7 123 1.6E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS15175 193fb57a19120f9c19de0a801b541d37 200 SUPERFAMILY SSF55729 110 199 1.63E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS15175 193fb57a19120f9c19de0a801b541d37 200 Pfam PF08445 FR47-like protein 99 182 4.3E-6 T 29-03-2018 IPR013653 FR47-like GO:0016747 MSG_RS15175 193fb57a19120f9c19de0a801b541d37 200 Gene3D G3DSA:3.40.630.30 12 196 1.4E-14 T 29-03-2018 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 SUPERFAMILY SSF100950 53 377 1.47E-103 T 29-03-2018 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Gene3D G3DSA:3.40.50.10470 176 379 1.9E-63 T 29-03-2018 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 387 569 2.6E-43 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 80 374 3.6E-97 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 SMART SM01007 387 570 1.5E-55 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Pfam PF01008 Initiation factor 2 subunit family 94 374 1.7E-67 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 390 569 3.3E-48 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 54 373 8.0E-116 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 SUPERFAMILY SSF53639 387 572 1.39E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Gene3D G3DSA:1.20.120.420 50 175 2.7E-35 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 51 385 36.227 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MSG_RS16605 b5e1b9b885ad32f45c67ee5038e248cf 587 Gene3D G3DSA:3.40.225.10 380 574 1.1E-49 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 PIRSF PIRSF000654 7 245 1.2E-19 T 29-03-2018 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 Gene3D G3DSA:1.10.510.10 87 255 2.1E-42 T 29-03-2018 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 110 122 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 SMART SM00220 1 252 3.9E-41 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 Pfam PF00069 Protein kinase domain 2 204 1.5E-38 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 Gene3D G3DSA:3.30.200.20 1 86 2.3E-17 T 29-03-2018 MSG_RS14470 1d64262a653162bdc7aa0fd893ba9183 366 SUPERFAMILY SSF56112 1 293 1.15E-67 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS17250 51f2291cc37616403740f754b9cced97 275 Gene3D G3DSA:1.10.8.50 127 275 2.0E-48 T 29-03-2018 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 218 1.5E-22 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 SMART SM01232 133 225 1.1E-31 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 Pfam PF06827 Zinc finger found in FPG and IleRS 247 274 3.4E-5 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 SUPERFAMILY SSF46946 132 216 4.12E-24 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 SUPERFAMILY SSF81624 2 134 2.75E-18 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 SMART SM00898 2 119 1.2E-13 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 SUPERFAMILY SSF57716 238 274 2.08E-10 T 29-03-2018 MSG_RS17250 51f2291cc37616403740f754b9cced97 275 Gene3D G3DSA:3.20.190.10 2 126 1.0E-14 T 29-03-2018 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Pfam PF13426 PAS domain 312 410 3.6E-8 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Gene3D G3DSA:1.20.5.1000 411 492 2.0E-12 T 29-03-2018 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SUPERFAMILY SSF53335 72 266 1.47E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Pfam PF13188 PAS domain 501 548 2.3E-4 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 57 5.6E-14 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SMART SM00138 6 267 3.4E-78 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SUPERFAMILY SSF55785 301 409 1.34E-9 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SMART SM00091 297 362 7.0 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SMART SM00091 500 566 0.0083 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Gene3D G3DSA:3.30.450.20 493 612 1.4E-13 T 29-03-2018 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SUPERFAMILY SSF47757 4 74 9.68E-14 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Gene3D G3DSA:3.40.50.150 71 269 1.4E-44 T 29-03-2018 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 4.5E-28 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Pfam PF01739 CheR methyltransferase, SAM binding domain 72 262 5.1E-52 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MSG_RS06580 107a48630ebb61a359198bffab788dda 614 SUPERFAMILY SSF55785 489 604 5.58E-12 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Gene3D G3DSA:1.10.155.10 2 69 2.0E-13 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MSG_RS06580 107a48630ebb61a359198bffab788dda 614 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 301 410 1.5E-8 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 497 599 2.8E-6 T 29-03-2018 IPR000014 PAS domain MSG_RS06580 107a48630ebb61a359198bffab788dda 614 Gene3D G3DSA:3.30.450.20 299 410 4.4E-13 T 29-03-2018 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 SUPERFAMILY SSF81799 134 235 2.09E-34 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 Gene3D G3DSA:3.40.50.150 8 139 1.1E-4 T 29-03-2018 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 SUPERFAMILY SSF53335 15 133 6.11E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS15160 5351ea478001be9f4f9d769408415631 346 SUPERFAMILY SSF53335 235 330 6.11E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS15160 5351ea478001be9f4f9d769408415631 346 Pfam PF01795 MraW methylase family 13 329 1.5E-114 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 Gene3D G3DSA:1.10.150.170 140 237 2.8E-38 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 PIRSF PIRSF004486 10 331 2.7E-95 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 15 330 36.531 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS15160 5351ea478001be9f4f9d769408415631 346 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 11 329 3.5E-86 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 Gene3D G3DSA:1.10.10.10 13 84 7.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 SUPERFAMILY SSF46785 17 89 2.86E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 SMART SM00866 106 244 5.0E-17 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 85 1.3E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 SMART SM00345 26 85 1.0E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 Pfam PF07702 UTRA domain 109 229 1.2E-21 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 Gene3D G3DSA:3.40.1410.10 85 248 6.4E-29 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 1.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 1.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17055 50d16432a68d3e87850df6142d581e26 271 SUPERFAMILY SSF64288 73 242 4.24E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS15595 43aebb5285a812609115b75fc482d152 271 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 21 238 2.9E-42 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS18630 1078deeb6c3b39ac2a4ca4cc9441c1d3 318 SUPERFAMILY SSF159245 3 290 4.32E-12 T 29-03-2018 MSG_RS05900 8d98cf38a9fed54e966864e05e0ca715 210 Gene3D G3DSA:3.40.50.300 1 209 2.0E-30 T 29-03-2018 MSG_RS05900 8d98cf38a9fed54e966864e05e0ca715 210 ProSitePatterns PS01331 Thymidylate kinase signature. 92 104 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MSG_RS05900 8d98cf38a9fed54e966864e05e0ca715 210 SUPERFAMILY SSF52540 2 198 3.02E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05900 8d98cf38a9fed54e966864e05e0ca715 210 Pfam PF02223 Thymidylate kinase 5 196 2.1E-21 T 29-03-2018 MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 126 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 8.6E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 SUPERFAMILY SSF51735 11 258 5.03E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 Pfam PF00106 short chain dehydrogenase 12 127 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 Gene3D G3DSA:3.40.50.720 3 270 5.5E-42 T 29-03-2018 MSG_RS19290 0c41683892d5bc5647240e5b5f491591 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 158 256 3.4E-18 T 29-03-2018 MSG_RS05760 62236fba4d40aa89c4c7953f6b5feba7 308 Gene3D G3DSA:3.40.50.150 1 278 1.1E-51 T 29-03-2018 MSG_RS05760 62236fba4d40aa89c4c7953f6b5feba7 308 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 277 4.9E-69 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS05760 62236fba4d40aa89c4c7953f6b5feba7 308 Pfam PF04072 Leucine carboxyl methyltransferase 19 206 3.6E-61 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS05760 62236fba4d40aa89c4c7953f6b5feba7 308 SUPERFAMILY SSF53335 15 300 2.43E-69 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 SUPERFAMILY SSF53098 141 282 6.45E-20 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 Gene3D G3DSA:1.10.10.10 7 68 2.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 Gene3D G3DSA:3.30.420.10 133 299 1.0E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 SUPERFAMILY SSF46689 9 115 1.09E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 Pfam PF13565 Homeodomain-like domain 42 113 8.9E-12 T 29-03-2018 MSG_RS20170 456b4a7ee3b97bc50e6d4a4f8f849e47 300 Pfam PF00665 Integrase core domain 142 258 1.4E-17 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS23160 24f44a56cb77725804f0c38c4e856261 383 Gene3D G3DSA:3.40.50.300 3 378 4.1E-85 T 29-03-2018 MSG_RS23160 24f44a56cb77725804f0c38c4e856261 383 Pfam PF02374 Anion-transporting ATPase 20 285 1.4E-26 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MSG_RS23160 24f44a56cb77725804f0c38c4e856261 383 SUPERFAMILY SSF52540 17 181 7.4E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23160 24f44a56cb77725804f0c38c4e856261 383 SUPERFAMILY SSF52540 226 287 7.4E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 Gene3D G3DSA:3.40.50.980 8 170 4.8E-25 T 29-03-2018 MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 SUPERFAMILY SSF56801 3 549 4.97E-103 T 29-03-2018 MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 Gene3D G3DSA:3.30.300.30 445 547 1.5E-13 T 29-03-2018 MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 Gene3D G3DSA:2.30.38.10 356 444 4.8E-20 T 29-03-2018 MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 Gene3D G3DSA:3.40.50.980 171 338 4.2E-35 T 29-03-2018 MSG_RS01385 489366a7a6245301da594c1fdc01ad16 580 Pfam PF00501 AMP-binding enzyme 32 452 4.9E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 SUPERFAMILY SSF56801 4 508 3.4E-125 T 29-03-2018 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Gene3D G3DSA:3.30.300.30 405 513 2.2E-24 T 29-03-2018 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Pfam PF00501 AMP-binding enzyme 11 408 2.0E-73 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Gene3D G3DSA:2.30.38.10 322 401 2.8E-15 T 29-03-2018 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 495 8.5E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Gene3D G3DSA:3.40.50.980 163 321 6.4E-38 T 29-03-2018 MSG_RS12540 c6b67da66922ccef0b962345e56cc44e 514 Gene3D G3DSA:3.40.50.980 2 162 1.4E-31 T 29-03-2018 MSG_RS14180 9f0575b481a1ffb4b62bed88ecfea0b9 384 Pfam PF00999 Sodium/hydrogen exchanger family 19 364 7.7E-28 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MSG_RS14180 9f0575b481a1ffb4b62bed88ecfea0b9 384 Gene3D G3DSA:1.20.91.10 230 315 1.8E-6 T 29-03-2018 MSG_RS13405 82df205a7b983b803fa6d85512bd94c2 387 SUPERFAMILY SSF51679 4 345 9.42E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS13405 82df205a7b983b803fa6d85512bd94c2 387 Gene3D G3DSA:3.20.20.30 11 387 1.1E-69 T 29-03-2018 MSG_RS13405 82df205a7b983b803fa6d85512bd94c2 387 Pfam PF00296 Luciferase-like monooxygenase 5 311 4.6E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 Gene3D G3DSA:1.10.10.60 17 58 1.1E-18 T 29-03-2018 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 SUPERFAMILY SSF46689 16 83 6.48E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS05135 d6d14396364bb99c7de0fccf2d5cec3d 192 Gene3D G3DSA:1.10.10.60 59 177 2.2E-8 T 29-03-2018 MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 Gene3D G3DSA:3.40.50.1820 219 436 4.9E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 SUPERFAMILY SSF53474 227 435 1.82E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 Pfam PF00156 Phosphoribosyl transferase domain 15 192 4.1E-22 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 Pfam PF01738 Dienelactone hydrolase family 242 423 3.3E-5 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 Gene3D G3DSA:3.40.50.2020 2 212 3.0E-35 T 29-03-2018 MSG_RS14110 20a11701c619eee8e218e1a9e53f6ce6 448 SUPERFAMILY SSF53271 3 210 3.28E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS01475 b9558be4697c960e122459ff19a9f13a 125 Gene3D G3DSA:3.10.450.50 2 114 3.1E-16 T 29-03-2018 MSG_RS01475 b9558be4697c960e122459ff19a9f13a 125 Pfam PF12680 SnoaL-like domain 3 99 1.1E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS01475 b9558be4697c960e122459ff19a9f13a 125 SUPERFAMILY SSF54427 4 113 2.85E-22 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.8E-68 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 SUPERFAMILY SSF56770 9 152 7.46E-65 T 29-03-2018 MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 Gene3D G3DSA:3.40.50.700 12 172 1.1E-40 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.558 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06760 a76b3ae3a59a06d98c38975baff7d283 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.2E-24 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS23020 9381437d2166b9da4d9190b2b41b5360 63 Pfam PF14029 Protein of unknown function (DUF4244) 9 60 1.2E-23 T 29-03-2018 IPR025338 Protein of unknown function DUF4244 MSG_RS06270 488acce78286cd625e78b0468c667610 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 2.9E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06270 488acce78286cd625e78b0468c667610 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 2.9E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06270 488acce78286cd625e78b0468c667610 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 2.9E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06270 488acce78286cd625e78b0468c667610 261 Gene3D G3DSA:3.40.50.1820 2 261 1.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06270 488acce78286cd625e78b0468c667610 261 SUPERFAMILY SSF53474 3 259 3.89E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06270 488acce78286cd625e78b0468c667610 261 Pfam PF12697 Alpha/beta hydrolase family 18 252 4.7E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 Gene3D G3DSA:1.20.1250.20 12 203 6.3E-29 T 29-03-2018 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 ProSitePatterns PS00217 Sugar transport proteins signature 2. 109 134 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 SUPERFAMILY SSF103473 16 441 1.2E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 18 440 2.2E-89 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 Pfam PF00083 Sugar (and other) transporter 17 444 6.0E-96 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 PRINTS PR00171 Sugar transporter signature 104 123 3.7E-20 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 PRINTS PR00171 Sugar transporter signature 259 269 3.7E-20 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 PRINTS PR00171 Sugar transporter signature 345 366 3.7E-20 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 PRINTS PR00171 Sugar transporter signature 21 31 3.7E-20 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 PRINTS PR00171 Sugar transporter signature 368 380 3.7E-20 T 29-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 Gene3D G3DSA:1.20.1250.20 224 454 1.5E-28 T 29-03-2018 MSG_RS05405 7ad11937608aa00bc58f6cb079498269 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 320 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS21440 b9ce1e94a5225d3382a79b7be3710a97 330 SUPERFAMILY SSF102198 105 329 9.55E-24 T 29-03-2018 MSG_RS21440 b9ce1e94a5225d3382a79b7be3710a97 330 Pfam PF04199 Putative cyclase 103 261 9.8E-21 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MSG_RS21440 b9ce1e94a5225d3382a79b7be3710a97 330 Gene3D G3DSA:3.50.30.50 46 330 8.3E-52 T 29-03-2018 MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 SUPERFAMILY SSF48498 98 202 1.04E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 4.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 Gene3D G3DSA:1.10.357.10 80 204 3.4E-19 T 29-03-2018 MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 Pfam PF13305 WHG domain 104 181 1.1E-12 T 29-03-2018 IPR025996 WHG domain MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 SUPERFAMILY SSF46689 21 86 1.33E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 Gene3D G3DSA:1.10.10.60 11 51 3.6E-10 T 29-03-2018 MSG_RS04275 33f9516cc0c389b86a4ab6ae17a13624 214 Gene3D G3DSA:1.10.260.40 52 79 6.4E-5 T 29-03-2018 MSG_RS17825 eb8229c3ff7915331a2f47f4cdabd78f 225 Gene3D G3DSA:3.40.50.300 1 206 3.4E-13 T 29-03-2018 MSG_RS17825 eb8229c3ff7915331a2f47f4cdabd78f 225 SUPERFAMILY SSF52540 12 200 6.33E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS15445 6c106ca3a2015a399fe4ac288311fd03 251 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 32 240 2.0E-80 T 29-03-2018 MSG_RS15445 6c106ca3a2015a399fe4ac288311fd03 251 Pfam PF13829 Domain of unknown function (DUF4191) 23 242 2.9E-84 T 29-03-2018 IPR025445 Protein of unknown function DUF4191 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 303 315 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 SUPERFAMILY SSF52425 3 170 5.49E-44 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 Gene3D G3DSA:1.25.40.80 137 268 1.7E-34 T 29-03-2018 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 Gene3D G3DSA:3.40.50.620 2 136 8.8E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 323 342 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 Gene3D G3DSA:1.10.579.10 269 442 1.8E-69 T 29-03-2018 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 SUPERFAMILY SSF48173 184 441 3.66E-94 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 Pfam PF00875 DNA photolyase 3 156 8.9E-41 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 PRINTS PR00147 DNA photolyase signature 323 341 1.2E-25 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 PRINTS PR00147 DNA photolyase signature 131 147 1.2E-25 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 PRINTS PR00147 DNA photolyase signature 362 376 1.2E-25 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 PRINTS PR00147 DNA photolyase signature 303 319 1.2E-25 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MSG_RS07525 4fb0025f0dd84691642dc02f69bac2ae 442 Pfam PF03441 FAD binding domain of DNA photolyase 251 440 3.6E-74 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 PIRSF PIRSF001348 1 613 4.1E-290 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 SUPERFAMILY SSF68923 12 248 2.72E-94 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Gene3D G3DSA:3.40.449.10 7 248 8.5E-108 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Gene3D G3DSA:3.90.228.20 331 612 1.1E-123 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Gene3D G3DSA:3.90.228.20 249 320 3.7E-20 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 29-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 609 2.2E-170 T 29-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 610 51.077 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 244 1.1E-98 T 29-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS01950 d82e221dbb5d39a14fb5535af699a641 613 SUPERFAMILY SSF53795 249 610 3.2E-155 T 29-03-2018 MSG_RS05300 8113d15b344876d4c63a5103d27231ee 405 Gene3D G3DSA:3.20.20.70 7 403 7.8E-87 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS05300 8113d15b344876d4c63a5103d27231ee 405 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 11 251 6.9E-43 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MSG_RS05300 8113d15b344876d4c63a5103d27231ee 405 SUPERFAMILY SSF51395 7 269 1.58E-87 T 29-03-2018 MSG_RS05300 8113d15b344876d4c63a5103d27231ee 405 SUPERFAMILY SSF51395 304 392 1.58E-87 T 29-03-2018 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 Pfam PF03466 LysR substrate binding domain 87 294 1.4E-36 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 SUPERFAMILY SSF53850 88 294 1.28E-36 T 29-03-2018 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 Gene3D G3DSA:3.40.190.10 80 183 7.6E-24 T 29-03-2018 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 SUPERFAMILY SSF46785 2 87 3.38E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 Gene3D G3DSA:3.40.190.10 184 264 3.1E-19 T 29-03-2018 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02720 c554e3589183e0d1a8bc5b3707e35236 313 Gene3D G3DSA:1.10.10.10 1 79 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 Gene3D G3DSA:3.30.1390.10 60 131 6.0E-29 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 131 23.989 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 SUPERFAMILY SSF54736 59 131 1.41E-21 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 131 6.2E-50 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 64 131 6.0E-28 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 65 104 2.0E-14 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 3.9E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 Gene3D G3DSA:1.20.5.710 4 59 1.4E-16 T 29-03-2018 MSG_RS04185 08ff8de4d6d15fb1532c2bf0b539e6b0 131 SUPERFAMILY SSF48300 5 66 6.41E-14 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00855 999afd997169374923fae154d88a8c08 140 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 62 125 2.8E-20 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS00855 999afd997169374923fae154d88a8c08 140 Gene3D G3DSA:2.40.50.140 67 127 1.3E-19 T 29-03-2018 MSG_RS00855 999afd997169374923fae154d88a8c08 140 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 25 60 7.1E-11 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS00855 999afd997169374923fae154d88a8c08 140 SUPERFAMILY SSF50249 13 133 3.6E-34 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 SUPERFAMILY SSF55190 5 113 3.79E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 10 550 5.0E-124 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Gene3D G3DSA:3.30.1360.70 3 109 7.8E-29 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 22 93 1.3E-21 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.5E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.5E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.5E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.5E-23 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Pfam PF05746 DALR anticodon binding domain 429 550 4.2E-41 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Gene3D G3DSA:3.40.50.620 110 356 8.8E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Gene3D G3DSA:1.10.730.10 395 550 1.0E-54 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Pfam PF00750 tRNA synthetases class I (R) 122 390 3.6E-15 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 SMART SM01016 4 93 6.2E-34 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 SMART SM00836 429 550 1.7E-55 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 SUPERFAMILY SSF47323 423 550 6.34E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 25.578 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MSG_RS18340 4fc83b7e2fc6a2cfdd80c13b36a4efac 550 SUPERFAMILY SSF52374 121 438 4.29E-79 T 29-03-2018 MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 251 326 3.4E-5 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 Gene3D G3DSA:3.30.70.1400 42 264 1.8E-28 T 29-03-2018 MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 SUPERFAMILY SSF103025 18 267 3.77E-54 T 29-03-2018 MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 19 237 4.2E-20 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 Gene3D G3DSA:2.40.30.110 266 339 1.8E-8 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 209 277 1.0E-19 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site MSG_RS21755 e5ca3e4b703371b1abfe59ec7b49beb0 365 PIRSF PIRSF006487 13 347 3.7E-11 T 29-03-2018 MSG_RS19375 2d1675ccb6ee8ea19a6c9a72b4549b22 102 Gene3D G3DSA:1.10.10.10 14 63 2.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19375 2d1675ccb6ee8ea19a6c9a72b4549b22 102 Pfam PF03861 ANTAR domain 18 62 9.6E-7 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 Pfam PF00202 Aminotransferase class-III 23 406 8.7E-111 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 268 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 PIRSF PIRSF000521 8 166 3.5E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 PIRSF PIRSF000521 181 409 6.2E-28 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 Gene3D G3DSA:3.90.1150.10 7 185 6.1E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 Gene3D G3DSA:3.90.1150.10 303 410 3.5E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 15 406 6.9E-141 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 SUPERFAMILY SSF53383 16 408 1.03E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS16425 a9db6c8e45ac005bd5f566c6c8ad28c8 410 Gene3D G3DSA:3.40.640.10 186 302 5.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS24560 8836ac1ac46e9ba88fbfe7f99ae46204 340 Gene3D G3DSA:3.40.50.2000 13 184 7.7E-4 T 29-03-2018 MSG_RS24560 8836ac1ac46e9ba88fbfe7f99ae46204 340 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 146 302 1.6E-8 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MSG_RS24560 8836ac1ac46e9ba88fbfe7f99ae46204 340 SUPERFAMILY SSF53756 19 333 1.85E-30 T 29-03-2018 MSG_RS24560 8836ac1ac46e9ba88fbfe7f99ae46204 340 Gene3D G3DSA:3.40.50.2000 185 337 5.2E-20 T 29-03-2018 MSG_RS19700 c15798aa6dd45ec27887395c4accfccd 334 Pfam PF01734 Patatin-like phospholipase 3 161 1.1E-16 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MSG_RS19700 c15798aa6dd45ec27887395c4accfccd 334 Gene3D G3DSA:3.40.1090.10 1 244 1.5E-32 T 29-03-2018 MSG_RS19700 c15798aa6dd45ec27887395c4accfccd 334 SUPERFAMILY SSF52151 239 308 1.26E-44 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS19700 c15798aa6dd45ec27887395c4accfccd 334 SUPERFAMILY SSF52151 1 175 1.26E-44 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS11640 64c24c68f3f445d1edd20351c152d328 75 Gene3D G3DSA:2.20.25.10 9 71 2.2E-19 T 29-03-2018 MSG_RS11640 64c24c68f3f445d1edd20351c152d328 75 SUPERFAMILY SSF158997 1 60 1.57E-15 T 29-03-2018 MSG_RS11640 64c24c68f3f445d1edd20351c152d328 75 Pfam PF03966 Trm112p-like protein 3 45 1.1E-7 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 MSG_RS04445 7ec7fbeef29b26b2885cb9a4c3e7ec2a 363 Gene3D G3DSA:1.10.260.40 10 70 6.3E-10 T 29-03-2018 MSG_RS04445 7ec7fbeef29b26b2885cb9a4c3e7ec2a 363 Pfam PF06114 IrrE N-terminal-like domain 161 272 1.6E-17 T 29-03-2018 IPR010359 IrrE N-terminal-like domain MSG_RS04445 7ec7fbeef29b26b2885cb9a4c3e7ec2a 363 SUPERFAMILY SSF47413 11 71 5.63E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS04445 7ec7fbeef29b26b2885cb9a4c3e7ec2a 363 SMART SM00530 11 66 1.2E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS04445 7ec7fbeef29b26b2885cb9a4c3e7ec2a 363 Pfam PF12844 Helix-turn-helix domain 12 69 4.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.7E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.7E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.7E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 SUPERFAMILY SSF54862 2 63 2.47E-13 T 29-03-2018 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 Pfam PF13459 4Fe-4S single cluster domain 3 62 2.1E-15 T 29-03-2018 MSG_RS21145 c897c7d3f4264c96dac448f5c918a91a 66 Gene3D G3DSA:3.30.70.20 1 65 1.8E-8 T 29-03-2018 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 SUPERFAMILY SSF82866 727 936 2.22E-31 T 29-03-2018 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 SUPERFAMILY SSF82866 139 357 3.4E-28 T 29-03-2018 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 Gene3D G3DSA:1.20.1640.10 153 359 1.0E-30 T 29-03-2018 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 Gene3D G3DSA:1.20.1640.10 721 933 1.9E-27 T 29-03-2018 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 TIGRFAM TIGR00833 actII: transport protein 28 936 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 Pfam PF03176 MMPL family 61 389 1.7E-114 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 Pfam PF03176 MMPL family 609 944 5.7E-106 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS10870 4f5bc4358673f46782ca949bc11d32c7 980 Gene3D G3DSA:1.20.120.570 512 682 0.0013 T 29-03-2018 MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 SMART SM00052 508 753 5.4E-92 T 29-03-2018 IPR001633 EAL domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 326 485 2.6E-30 T 29-03-2018 IPR000160 GGDEF domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 SMART SM00267 316 489 5.1E-38 T 29-03-2018 IPR000160 GGDEF domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 Gene3D G3DSA:3.20.20.450 494 757 3.6E-88 T 29-03-2018 IPR001633 EAL domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 Gene3D G3DSA:3.30.70.270 321 493 5.7E-43 T 29-03-2018 MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 SUPERFAMILY SSF141868 514 757 1.44E-77 T 29-03-2018 IPR001633 EAL domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 479 1.4E-32 T 29-03-2018 IPR000160 GGDEF domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 Pfam PF00563 EAL domain 515 748 1.3E-69 T 29-03-2018 IPR001633 EAL domain MSG_RS16175 ee20506d853390f0ec4b6635932fb8c5 766 SUPERFAMILY SSF55073 333 491 8.63E-34 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 2.1E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 221 7.1E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Gene3D G3DSA:1.10.540.10 1 123 1.1E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Gene3D G3DSA:2.40.110.10 124 220 4.7E-35 T 29-03-2018 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 SUPERFAMILY SSF56645 3 246 8.9E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Gene3D G3DSA:1.20.140.10 221 386 2.0E-37 T 29-03-2018 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 383 2.2E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16970 c97f5b12ab5d79e8241549add8d107fa 386 SUPERFAMILY SSF47203 233 386 2.42E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 Gene3D G3DSA:3.40.50.980 192 389 1.5E-40 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 Pfam PF00501 AMP-binding enzyme 27 468 4.8E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 Gene3D G3DSA:3.30.300.30 463 599 6.6E-16 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 Gene3D G3DSA:2.30.38.10 390 461 1.8E-18 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 SUPERFAMILY SSF56801 339 509 2.62E-109 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 SUPERFAMILY SSF56801 21 291 2.62E-109 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 SUPERFAMILY SSF56801 540 598 2.62E-109 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 Gene3D G3DSA:3.40.50.980 15 191 2.5E-36 T 29-03-2018 MSG_RS16195 070ac4ab63b570b66c9d762152cdd6e1 599 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS15205 be563707f686d49e9523887b743c10aa 396 Gene3D G3DSA:3.30.200.20 1 88 5.1E-19 T 29-03-2018 MSG_RS15205 be563707f686d49e9523887b743c10aa 396 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS15205 be563707f686d49e9523887b743c10aa 396 PIRSF PIRSF000654 24 270 7.7E-21 T 29-03-2018 MSG_RS15205 be563707f686d49e9523887b743c10aa 396 Pfam PF00069 Protein kinase domain 8 253 8.0E-47 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS15205 be563707f686d49e9523887b743c10aa 396 SUPERFAMILY SSF56112 3 319 3.63E-73 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS15205 be563707f686d49e9523887b743c10aa 396 SMART SM00220 6 265 2.8E-56 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS15205 be563707f686d49e9523887b743c10aa 396 Gene3D G3DSA:1.10.510.10 89 336 3.5E-48 T 29-03-2018 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 PRINTS PR00126 ATP synthase gamma subunit signature 275 296 1.1E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 PRINTS PR00126 ATP synthase gamma subunit signature 244 263 1.1E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.1E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 PRINTS PR00126 ATP synthase gamma subunit signature 176 193 1.1E-34 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Gene3D G3DSA:1.10.287.80 188 250 2.2E-17 T 29-03-2018 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Pfam PF00231 ATP synthase 4 297 6.3E-87 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 SUPERFAMILY SSF52943 3 297 5.36E-79 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 297 33.772 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 283 296 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Gene3D G3DSA:3.40.1380.10 63 187 7.0E-40 T 29-03-2018 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Gene3D G3DSA:1.10.287.80 251 292 4.8E-11 T 29-03-2018 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 Gene3D G3DSA:1.10.287.80 3 60 5.0E-12 T 29-03-2018 MSG_RS18250 5d16bb4070ab748d694de4235cdca900 303 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 297 1.1E-106 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Gene3D G3DSA:2.170.190.11 55 159 5.0E-27 T 29-03-2018 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 185 2.5E-38 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 SUPERFAMILY SSF63882 88 194 2.22E-39 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 SUPERFAMILY SSF63882 2 61 2.22E-39 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 195 333 1.9E-26 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 SUPERFAMILY SSF53218 195 341 1.28E-30 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Gene3D G3DSA:3.90.105.10 22 54 1.5E-4 T 29-03-2018 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Pfam PF03454 MoeA C-terminal region (domain IV) 350 426 1.3E-19 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Gene3D G3DSA:2.40.340.10 349 428 1.8E-21 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Pfam PF00994 Probable molybdopterin binding domain 199 336 7.0E-18 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 Gene3D G3DSA:3.40.980.10 168 344 2.9E-41 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 SMART SM00852 198 337 2.3E-20 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20190 8ed7fe443cc9762468dcc99749f1abdb 430 SUPERFAMILY SSF63867 347 426 4.45E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 Gene3D G3DSA:2.130.10.120 2 350 6.5E-20 T 29-03-2018 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 447 466 1.3E-6 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 477 497 1.3E-6 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 419 443 1.3E-6 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 393 411 1.3E-6 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 SUPERFAMILY SSF50993 254 350 2.51E-10 T 29-03-2018 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 SUPERFAMILY SSF50993 8 143 2.51E-10 T 29-03-2018 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 Gene3D G3DSA:3.40.50.1820 352 618 6.6E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 Pfam PF00326 Prolyl oligopeptidase family 413 617 3.1E-47 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MSG_RS04970 ebc7f4eb9f1a613b002c937a76970c40 623 SUPERFAMILY SSF53474 367 613 9.7E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 Pfam PF12698 ABC-2 family transporter protein 399 613 8.0E-18 T 29-03-2018 MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 Pfam PF12051 Protein of unknown function (DUF3533) 24 187 3.8E-10 T 29-03-2018 IPR022703 Domain of unknown function DUF3533 MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 206 229 2.4E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 369 393 2.2E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 183 209 1.9E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 347 373 1.9E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 171 1.1E-58 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 SUPERFAMILY SSF58104 193 401 3.66E-6 T 29-03-2018 MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 Gene3D G3DSA:3.40.1710.10 47 451 3.6E-25 T 29-03-2018 MSG_RS17820 d0d355495b3f518377ba56a5f9e9bf74 634 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 414 621 6.8E-73 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 334 417 8.2E-31 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 345 356 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 SUPERFAMILY SSF140490 328 427 3.79E-37 T 29-03-2018 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 SUPERFAMILY SSF142984 246 327 3.27E-22 T 29-03-2018 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 SMART SM00928 332 377 3.0E-23 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 223 5.2E-45 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 SUPERFAMILY SSF142019 6 243 1.96E-83 T 29-03-2018 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 Gene3D G3DSA:3.10.560.10 241 386 1.4E-4 T 29-03-2018 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 Pfam PF10531 SLBB domain 248 294 7.4E-9 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06740 4452490855dfc779060cb1c6c2800024 445 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 9 418 3.0E-195 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Gene3D G3DSA:3.40.50.980 155 315 4.1E-40 T 29-03-2018 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Gene3D G3DSA:2.30.38.10 321 396 3.5E-24 T 29-03-2018 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Pfam PF00501 AMP-binding enzyme 13 402 1.5E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 486 3.2E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Gene3D G3DSA:3.40.50.980 7 154 7.8E-39 T 29-03-2018 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 Gene3D G3DSA:3.30.300.30 397 505 8.8E-31 T 29-03-2018 MSG_RS00350 926b5ce353e613c722eeaf7e18713d57 505 SUPERFAMILY SSF56801 8 499 1.57E-142 T 29-03-2018 MSG_RS05785 95ee04f36772d7e078b7de2c61c9316c 479 Pfam PF02720 Domain of unknown function (DUF222) 24 328 4.3E-80 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS05785 95ee04f36772d7e078b7de2c61c9316c 479 Gene3D G3DSA:3.40.1800.10 314 383 1.6E-6 T 29-03-2018 MSG_RS05785 95ee04f36772d7e078b7de2c61c9316c 479 SMART SM00507 319 371 2.0E-6 T 29-03-2018 IPR003615 HNH nuclease MSG_RS08660 13a382120d36ba4550aa6b22ace27b18 153 Gene3D G3DSA:3.40.630.30 5 148 1.2E-18 T 29-03-2018 MSG_RS08660 13a382120d36ba4550aa6b22ace27b18 153 Pfam PF00583 Acetyltransferase (GNAT) family 36 122 4.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS08660 13a382120d36ba4550aa6b22ace27b18 153 SUPERFAMILY SSF55729 30 149 5.23E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS24100 5708774ce8d245179eca9aa8c5497497 1092 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 30 681 9.8E-276 T 29-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 MSG_RS24100 5708774ce8d245179eca9aa8c5497497 1092 Pfam PF14896 EmbC C-terminal domain 717 1091 2.0E-148 T 29-03-2018 IPR032731 Arabinosyltransferase, C-terminal MSG_RS24100 5708774ce8d245179eca9aa8c5497497 1092 Gene3D G3DSA:2.60.120.610 52 232 1.1E-57 T 29-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 209 3.9E-88 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 212 39.703 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 SUPERFAMILY SSF50447 3 215 1.32E-82 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 Gene3D G3DSA:4.10.960.10 59 170 8.4E-35 T 29-03-2018 MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 Pfam PF00297 Ribosomal protein L3 94 187 9.9E-18 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04460 5fcc4e3e01ed6d17f93abf11ccacfa72 217 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 SUPERFAMILY SSF53335 201 361 2.11E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 Gene3D G3DSA:3.40.1010.10 1 110 2.7E-13 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 PIRSF PIRSF036428 1 386 4.8E-127 T 29-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 182 4.1E-16 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 195 2.1E-36 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 Gene3D G3DSA:3.40.50.150 213 386 2.8E-20 T 29-03-2018 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 219 338 1.1E-26 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 SUPERFAMILY SSF53790 1 198 7.98E-32 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14640 9ea60663bd460067dbf1bce3a2176e2e 386 Gene3D G3DSA:3.30.950.10 111 204 7.0E-25 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 SUPERFAMILY SSF52518 6 374 2.44E-78 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 404 578 1.5E-87 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Gene3D G3DSA:3.40.50.970 2 381 2.9E-89 T 29-03-2018 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 ProSitePatterns PS60003 Phosphoketolase signature 2. 162 180 - T 29-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 PIRSF PIRSF017245 1 791 0.0 T 29-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Pfam PF09363 XFP C-terminal domain 589 789 6.3E-89 T 29-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Gene3D G3DSA:3.40.50.970 382 604 3.0E-34 T 29-03-2018 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 ProSitePatterns PS60002 Phosphoketolase signature 1. 149 155 - T 29-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Hamap MF_01403 Probable phosphoketolase. 10 791 40.78 T 29-03-2018 IPR023962 Probable phosphoketolase MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Pfam PF09364 XFP N-terminal domain 13 389 4.2E-189 T 29-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 SUPERFAMILY SSF52518 381 591 1.77E-24 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS13035 8535012a282f1728612187b171b8b2b4 792 Gene3D G3DSA:3.40.50.920 609 791 2.0E-81 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS04130 3fadd60e12121aaa90eb9308108cc17d 298 SUPERFAMILY SSF53335 18 294 6.05E-73 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04130 3fadd60e12121aaa90eb9308108cc17d 298 PIRSF PIRSF003085 1 298 2.1E-99 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS04130 3fadd60e12121aaa90eb9308108cc17d 298 Gene3D G3DSA:3.40.50.150 7 292 2.6E-48 T 29-03-2018 MSG_RS04130 3fadd60e12121aaa90eb9308108cc17d 298 Pfam PF02353 Mycolic acid cyclopropane synthetase 9 286 7.4E-116 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 SUPERFAMILY SSF56801 5 493 7.46E-130 T 29-03-2018 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Gene3D G3DSA:3.40.50.980 2 157 1.1E-39 T 29-03-2018 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Pfam PF00501 AMP-binding enzyme 14 405 3.1E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Gene3D G3DSA:2.30.38.10 309 375 2.3E-16 T 29-03-2018 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Gene3D G3DSA:3.40.50.980 158 308 1.4E-35 T 29-03-2018 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Gene3D G3DSA:3.30.300.30 400 493 8.1E-25 T 29-03-2018 MSG_RS21010 2cb897db47313a9bd1c68b79e5b6e54a 494 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 487 4.4E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS23460 4b51fe7e8021938fe2949476602746ad 467 SUPERFAMILY SSF55103 150 456 7.63E-13 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MSG_RS23460 4b51fe7e8021938fe2949476602746ad 467 Pfam PF01565 FAD binding domain 43 142 3.2E-9 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS23460 4b51fe7e8021938fe2949476602746ad 467 Gene3D G3DSA:3.30.465.10 56 196 3.2E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS23460 4b51fe7e8021938fe2949476602746ad 467 SUPERFAMILY SSF56176 38 174 1.26E-25 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 Gene3D G3DSA:3.40.50.980 182 352 4.3E-28 T 29-03-2018 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 Pfam PF00501 AMP-binding enzyme 18 433 5.5E-40 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 520 1.6E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 SUPERFAMILY SSF56801 5 533 1.11E-86 T 29-03-2018 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 Gene3D G3DSA:3.40.50.980 2 181 6.4E-22 T 29-03-2018 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 Gene3D G3DSA:3.30.300.30 431 533 6.0E-22 T 29-03-2018 MSG_RS17935 f6101dad038d540c66c172f914d2c690 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 710 3.2E-299 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Gene3D G3DSA:3.40.50.1000 478 606 4.7E-33 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Gene3D G3DSA:3.40.1110.10 350 477 1.0E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 472 633 1.4E-39 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 564 1.6E-33 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Gene3D G3DSA:1.20.1110.10 75 349 4.1E-29 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 550 569 3.4E-25 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 3.4E-25 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 507 3.4E-25 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 3.4E-25 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 573 585 3.4E-25 T 29-03-2018 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF56784 473 593 2.38E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF56784 322 346 2.38E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF56784 382 438 2.38E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF81653 133 222 4.32E-19 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 27 714 39.742 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF81665 223 328 1.57E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 SUPERFAMILY SSF81665 50 115 1.57E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS19810 dfa30301878d14c3a1a85ff390370676 717 Pfam PF00122 E1-E2 ATPase 132 312 2.5E-32 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Gene3D G3DSA:3.30.9.10 106 158 0.087 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Gene3D G3DSA:1.10.287.990 33 92 3.4E-16 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Gene3D G3DSA:3.40.50.720 159 328 2.9E-31 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 6.5E-24 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.5E-24 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 6.5E-24 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 6.5E-24 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 6.5E-24 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 4.5E-41 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 454 4.9E-28 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 SUPERFAMILY SSF51905 4 375 1.62E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 SUPERFAMILY SSF55424 342 456 2.23E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 3 458 4.2E-236 T 29-03-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 PIRSF PIRSF000350 1 446 1.8E-78 T 29-03-2018 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 319 1.7E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MSG_RS08460 adf79dd543052301fc0ab4d4e3887231 459 Gene3D G3DSA:3.30.390.30 334 458 8.1E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 SUPERFAMILY SSF55781 48 231 2.18E-35 T 29-03-2018 IPR029016 GAF domain-like MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Gene3D G3DSA:3.30.450.40 218 387 2.2E-26 T 29-03-2018 IPR029016 GAF domain-like MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Gene3D G3DSA:3.30.450.40 30 217 2.3E-35 T 29-03-2018 IPR029016 GAF domain-like MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 SUPERFAMILY SSF55874 480 577 2.45E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 SUPERFAMILY SSF55781 225 386 1.81E-19 T 29-03-2018 IPR029016 GAF domain-like MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Pfam PF13185 GAF domain 66 204 1.5E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Pfam PF13185 GAF domain 239 375 1.7E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Gene3D G3DSA:3.30.565.10 459 579 5.7E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 Pfam PF07730 Histidine kinase 392 447 3.9E-9 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 SMART SM00065 66 213 9.0E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS14080 bb2b7d24fb1f53ee32c81373dd69521b 579 SMART SM00065 217 384 0.017 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 SUPERFAMILY SSF47781 64 132 1.7E-19 T 29-03-2018 IPR010994 RuvA domain 2-like MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Gene3D G3DSA:1.10.150.20 66 136 1.0E-13 T 29-03-2018 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 SUPERFAMILY SSF50249 1 62 5.2E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Pfam PF14520 Helix-hairpin-helix domain 71 129 4.7E-16 T 29-03-2018 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 SUPERFAMILY SSF46929 151 202 4.05E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Gene3D G3DSA:2.40.50.140 1 62 4.8E-25 T 29-03-2018 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Gene3D G3DSA:1.10.8.10 140 204 1.6E-13 T 29-03-2018 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 29.35 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 177 7.3E-38 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Pfam PF07499 RuvA, C-terminal domain 155 200 1.8E-8 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 Pfam PF01330 RuvA N terminal domain 1 61 5.9E-20 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 SMART SM00278 72 91 280.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS09665 772e8f5f3298c79f11bd11d46c1fa1b0 204 SMART SM00278 107 126 1.3 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MSG_RS21885 a7eaa6f2286f92cb3701fec0abf03cb1 132 SUPERFAMILY SSF54593 4 130 4.68E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS21885 a7eaa6f2286f92cb3701fec0abf03cb1 132 Gene3D G3DSA:3.10.180.10 9 132 3.1E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS21885 a7eaa6f2286f92cb3701fec0abf03cb1 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 129 1.3E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 SUPERFAMILY SSF50331 246 329 4.46E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 10 246 7.8E-127 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 SMART SM00382 34 217 3.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 SUPERFAMILY SSF52540 10 246 1.1E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 Pfam PF12857 TOBE-like domain 279 330 1.1E-9 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 Pfam PF00005 ABC transporter 25 167 8.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 Gene3D G3DSA:2.40.50.100 259 330 1.1E-12 T 29-03-2018 MSG_RS16875 b27b4b7ad8ef829ee0eb3ee3c15088f1 353 Gene3D G3DSA:3.40.50.300 6 258 1.4E-79 T 29-03-2018 MSG_RS14350 f7bfa70fc45c3dca48134c85abe8ed18 174 SUPERFAMILY SSF82784 7 169 5.63E-34 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS14350 f7bfa70fc45c3dca48134c85abe8ed18 174 Gene3D G3DSA:3.30.300.20 19 172 2.2E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS14350 f7bfa70fc45c3dca48134c85abe8ed18 174 Pfam PF02566 OsmC-like protein 62 168 7.8E-22 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 1670 1911 1.0E-54 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00668 Condensation domain 2546 2853 2.3E-29 T 29-03-2018 IPR001242 Condensation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00668 Condensation domain 1492 1922 2.6E-78 T 29-03-2018 IPR001242 Condensation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00668 Condensation domain 9 334 1.3E-34 T 29-03-2018 IPR001242 Condensation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00668 Condensation domain 2993 3403 5.6E-79 T 29-03-2018 IPR001242 Condensation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00668 Condensation domain 1041 1382 4.7E-27 T 29-03-2018 IPR001242 Condensation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.300.30 2340 2453 1.8E-35 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.300.30 838 949 4.9E-36 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF56801 415 959 1.44E-145 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF13193 AMP-binding enzyme C-terminal domain 2353 2424 5.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF13193 AMP-binding enzyme C-terminal domain 851 922 9.4E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.559.10 2974 3181 3.7E-40 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.559.10 1473 1678 7.6E-40 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 10 183 3.56E-27 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF47336 2442 2514 4.71E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF47336 938 1008 3.14E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 1214 1462 4.56E-26 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 ProSitePatterns PS00455 Putative AMP-binding domain signature. 598 609 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 3171 3404 4.67E-53 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 1024 1189 1.03E-23 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.559.10 2517 2711 5.7E-14 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.559.10 1010 1209 1.5E-15 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SMART SM00823 Phosphopantetheine attachment site 946 1014 0.038 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SMART SM00823 Phosphopantetheine attachment site 2450 2518 0.032 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 2528 2689 6.0E-22 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2474 2489 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:1.10.1200.10 2454 2516 9.9E-19 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:1.10.1200.10 950 1009 3.0E-18 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF56801 1901 2463 4.19E-144 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 1489 1684 5.11E-40 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2830 2985 1.2E-31 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1330 1485 9.1E-34 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00501 AMP-binding enzyme 460 843 1.3E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00501 AMP-binding enzyme 1947 2345 7.5E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:2.30.38.10 755 836 1.0E-21 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:2.30.38.10 2257 2338 1.6E-20 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 ProSitePatterns PS00012 Phosphopantetheine attachment site. 970 985 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 2704 2959 2.45E-26 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.40.50.980 450 603 1.4E-44 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.40.50.980 1939 2089 1.0E-44 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 189 424 6.78E-27 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00550 Phosphopantetheine attachment site 2453 2512 5.7E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Pfam PF00550 Phosphopantetheine attachment site 949 1008 5.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.30.559.10 8 209 2.0E-17 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 SUPERFAMILY SSF52777 2990 3185 7.11E-42 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1966 2369 3.1E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 480 867 5.0E-127 T 29-03-2018 IPR010071 Amino acid adenylation domain MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.40.50.980 2090 2253 4.4E-35 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 Gene3D G3DSA:3.40.50.980 604 749 4.3E-29 T 29-03-2018 MSG_RS10890 31c19b37562a357f00a784a2d089a41b 3408 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2084 2095 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS12115 2280e74484a7ca213ff5460c7c86141c 154 Pfam PF06210 Protein of unknown function (DUF1003) 55 141 7.0E-15 T 29-03-2018 IPR010406 Protein of unknown function DUF1003 MSG_RS16370 a961a40e101a60476ca66d08bbe5fa45 151 Pfam PF04075 F420H(2)-dependent quinone reductase 31 138 3.6E-25 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS16370 a961a40e101a60476ca66d08bbe5fa45 151 Gene3D G3DSA:2.30.110.10 17 143 2.4E-31 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS16370 a961a40e101a60476ca66d08bbe5fa45 151 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 141 7.4E-30 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS16370 a961a40e101a60476ca66d08bbe5fa45 151 SUPERFAMILY SSF50475 36 143 8.09E-8 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Gene3D G3DSA:2.170.190.11 55 140 3.7E-31 T 29-03-2018 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Pfam PF00994 Probable molybdopterin binding domain 180 317 3.3E-27 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 166 2.3E-42 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Pfam PF03454 MoeA C-terminal region (domain IV) 332 398 5.4E-16 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Gene3D G3DSA:3.40.980.10 149 328 3.7E-50 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 SUPERFAMILY SSF63867 327 398 4.19E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 SMART SM00852 179 318 1.4E-39 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 SUPERFAMILY SSF53218 177 324 3.4E-39 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 314 1.3E-32 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Gene3D G3DSA:2.40.340.10 331 399 1.0E-15 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 Gene3D G3DSA:3.90.105.10 22 54 4.0E-11 T 29-03-2018 MSG_RS03190 4349f15e173be9f67d515ac09235d7a8 399 SUPERFAMILY SSF63882 2 175 6.41E-50 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 SUPERFAMILY SSF51735 123 261 2.01E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 Gene3D G3DSA:3.90.180.10 7 144 1.3E-29 T 29-03-2018 MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 Pfam PF00107 Zinc-binding dehydrogenase 162 271 2.2E-13 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 Gene3D G3DSA:3.90.180.10 260 333 0.0015 T 29-03-2018 MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 SUPERFAMILY SSF50129 11 149 1.89E-29 T 29-03-2018 IPR011032 GroES-like MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 Gene3D G3DSA:3.40.50.720 145 259 8.9E-21 T 29-03-2018 MSG_RS21865 1a766f95c204382d4e2dd7aa45e676a5 333 SMART SM00829 20 330 5.4E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.6E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 Gene3D G3DSA:1.20.140.10 219 342 2.8E-28 T 29-03-2018 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 Gene3D G3DSA:1.10.540.10 1 121 1.5E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 338 1.1E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 SUPERFAMILY SSF47203 226 363 3.7E-31 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS19280 fbf1fdb4152b1ba5fe8f627b5bded650 366 SUPERFAMILY SSF56645 1 204 5.24E-26 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 3.0E-16 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 Gene3D G3DSA:2.40.50.100 20 83 1.6E-27 T 29-03-2018 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 2.3E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.4E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.4E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.4E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 SUPERFAMILY SSF110324 2 81 2.96E-31 T 29-03-2018 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 Pfam PF01016 Ribosomal L27 protein 2 80 4.5E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17145 a3aec3488b499adf88fae86677d98f44 88 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.241 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.2E-191 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 PIRSF PIRSF000183 1 371 6.0E-174 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 351 1.8E-79 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 SUPERFAMILY SSF51735 137 303 1.03E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 Gene3D G3DSA:3.40.50.720 195 371 9.1E-42 T 29-03-2018 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 Gene3D G3DSA:3.40.50.720 1 176 1.7E-47 T 29-03-2018 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 SMART SM01003 4 137 3.8E-77 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 Gene3D G3DSA:3.50.50.60 177 194 1.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 5.0E-46 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 29-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 SUPERFAMILY SSF52283 305 360 3.4E-64 T 29-03-2018 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 SUPERFAMILY SSF52283 1 137 3.4E-64 T 29-03-2018 MSG_RS08650 d132df5c6ff4937b3fd3ddbe43fa3978 371 SMART SM01002 149 297 1.2E-79 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MSG_RS00070 00481a38989dff50b48fb1c2411c05c2 141 Hamap MF_00927 Cell wall synthesis protein CwsA [cwsA]. 4 141 25.671 T 29-03-2018 IPR024245 Cell wall synthesis protein CwsA MSG_RS00070 00481a38989dff50b48fb1c2411c05c2 141 ProDom PD070500 MEMBRANE TRANSMEMBRANE MB0008C RV0008C/MT0010 1 100 1.0E-31 T 29-03-2018 IPR024245 Cell wall synthesis protein CwsA MSG_RS00070 00481a38989dff50b48fb1c2411c05c2 141 Pfam PF10814 Cell wall synthesis protein CwsA 9 141 2.1E-62 T 29-03-2018 IPR024245 Cell wall synthesis protein CwsA MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 SUPERFAMILY SSF48208 280 699 7.82E-19 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 Gene3D G3DSA:3.30.2080.10 593 759 8.2E-50 T 29-03-2018 MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 Pfam PF07971 Glycosyl hydrolase family 92 259 745 5.3E-143 T 29-03-2018 IPR012939 Glycosyl hydrolase family 92 MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 Gene3D G3DSA:1.20.1050.60 365 454 3.5E-22 T 29-03-2018 MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 30 749 1.7E-148 T 29-03-2018 IPR005887 Alpha-1,2-mannosidase, putative MSG_RS04005 2f599c59ecfe409e5b7652fb8c609b7f 873 Gene3D G3DSA:2.70.98.10 37 340 1.6E-85 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MSG_RS10795 05ca299c3560a997e8488ccfc95697e9 297 SUPERFAMILY SSF53335 48 259 1.03E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10795 05ca299c3560a997e8488ccfc95697e9 297 Pfam PF05050 Methyltransferase FkbM domain 98 254 3.4E-19 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS10795 05ca299c3560a997e8488ccfc95697e9 297 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 96 232 3.9E-34 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS10795 05ca299c3560a997e8488ccfc95697e9 297 Gene3D G3DSA:3.40.50.150 78 271 3.6E-38 T 29-03-2018 MSG_RS21015 04875735e6e2cf6165c5221df85c204e 396 Pfam PF04909 Amidohydrolase 103 389 7.1E-25 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS21015 04875735e6e2cf6165c5221df85c204e 396 SUPERFAMILY SSF51556 12 41 1.43E-60 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21015 04875735e6e2cf6165c5221df85c204e 396 SUPERFAMILY SSF51556 96 393 1.43E-60 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21015 04875735e6e2cf6165c5221df85c204e 396 Gene3D G3DSA:3.20.20.140 11 395 1.7E-57 T 29-03-2018 MSG_RS00125 be5c3a33c9651d82746f4ca5f5fe13aa 155 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 66 154 1.0E-15 T 29-03-2018 IPR032030 YscD, cytoplasmic domain MSG_RS00125 be5c3a33c9651d82746f4ca5f5fe13aa 155 Gene3D G3DSA:2.60.200.20 50 154 7.2E-21 T 29-03-2018 MSG_RS00125 be5c3a33c9651d82746f4ca5f5fe13aa 155 SMART SM00240 82 132 8.7E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS00125 be5c3a33c9651d82746f4ca5f5fe13aa 155 SUPERFAMILY SSF49879 54 153 7.08E-24 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS24590 2d5407ed66b0a638edc9a0cfd770e71b 512 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 10 326 9.8E-69 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS24590 2d5407ed66b0a638edc9a0cfd770e71b 512 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 164 253 3.6E-17 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Gene3D G3DSA:3.40.50.980 60 217 2.9E-27 T 29-03-2018 MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Gene3D G3DSA:3.30.300.30 449 555 2.2E-30 T 29-03-2018 MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 SUPERFAMILY SSF56801 61 548 3.79E-117 T 29-03-2018 MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 539 3.6E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Gene3D G3DSA:3.40.50.980 218 367 2.5E-34 T 29-03-2018 MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Gene3D G3DSA:2.30.38.10 368 448 5.7E-12 T 29-03-2018 MSG_RS05765 94e7a2c2d4276343c85d58042f6a8f71 556 Pfam PF00501 AMP-binding enzyme 67 455 1.8E-62 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.8E-21 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Gene3D G3DSA:2.40.50.140 65 126 1.5E-22 T 29-03-2018 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 PIRSF PIRSF005901 1 186 7.5E-65 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 5.9E-24 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Gene3D G3DSA:2.30.30.30 2 61 1.3E-25 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 SUPERFAMILY SSF50249 128 185 8.91E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.479 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Gene3D G3DSA:2.40.50.140 129 184 1.8E-25 T 29-03-2018 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 SUPERFAMILY SSF50104 3 63 5.52E-20 T 29-03-2018 IPR008991 Translation protein SH3-like domain MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.5E-73 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.4E-26 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 SMART SM00841 129 184 5.2E-32 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 SUPERFAMILY SSF50249 65 126 3.3E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS09945 32624156556b4d1dcafb98c9b8feb537 187 SMART SM01185 67 121 5.5E-27 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MSG_RS08440 b7e542e255bac32b5d6f17f24dc528ee 236 SUPERFAMILY SSF52317 25 230 2.78E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS08440 b7e542e255bac32b5d6f17f24dc528ee 236 Pfam PF07722 Peptidase C26 1 213 1.2E-64 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 MSG_RS08440 b7e542e255bac32b5d6f17f24dc528ee 236 Gene3D G3DSA:3.40.50.880 1 235 4.7E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 SUPERFAMILY SSF51430 18 292 4.06E-61 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 Pfam PF00248 Aldo/keto reductase family 21 291 1.4E-44 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 Gene3D G3DSA:3.20.20.100 10 300 1.4E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 PRINTS PR00069 Aldo-keto reductase signature 151 168 1.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS03815 3b6ead7f48dacdfd5b9272b22235df32 312 PRINTS PR00069 Aldo-keto reductase signature 225 249 1.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS22035 d4e2ad8bb9a7d219244abf8f09688bb3 184 SUPERFAMILY SSF54427 10 137 1.93E-16 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS22035 d4e2ad8bb9a7d219244abf8f09688bb3 184 Gene3D G3DSA:3.10.450.50 4 144 7.6E-14 T 29-03-2018 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 Gene3D G3DSA:1.10.10.60 13 67 2.6E-15 T 29-03-2018 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 Gene3D G3DSA:1.10.357.10 68 204 1.6E-20 T 29-03-2018 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 Pfam PF16859 Bacterial transcriptional repressor C-terminal 89 186 2.0E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 2.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 SUPERFAMILY SSF48498 91 202 4.45E-17 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21815 9213f1e97177d8023c777b307a063dd4 205 SUPERFAMILY SSF46689 19 80 1.7E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 SUPERFAMILY SSF158472 425 470 4.18E-10 T 29-03-2018 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 Pfam PF00672 HAMP domain 425 470 4.1E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 508 681 3.0E-39 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 Gene3D G3DSA:3.30.70.1230 500 687 1.5E-42 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 SMART SM00044 479 668 4.9E-36 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 Gene3D G3DSA:3.30.450.20 119 245 6.6E-9 T 29-03-2018 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 SMART SM00304 423 475 1.3E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 Gene3D G3DSA:3.30.450.20 246 392 4.3E-9 T 29-03-2018 MSG_RS17045 dc643fc4cf7c830b66e2f22f8a9b2ad5 687 SUPERFAMILY SSF55073 501 682 5.49E-46 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 SMART SM00382 210 392 1.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 Gene3D G3DSA:3.30.230.10 2 187 8.4E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 SUPERFAMILY SSF54211 3 168 4.17E-36 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 SUPERFAMILY SSF52540 188 418 1.04E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 SUPERFAMILY SSF52540 460 501 1.04E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 143 2.9E-38 T 29-03-2018 MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 401 497 1.6E-22 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 496 9.1E-137 T 29-03-2018 IPR004482 Mg chelatase-related protein MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 Gene3D G3DSA:3.40.50.300 188 433 2.7E-23 T 29-03-2018 MSG_RS08260 97ecd589666bb9e71a14b6243898ae05 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 393 2.3E-82 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain MSG_RS17350 eb5cc474fd34a783924c4abda4c7ddc8 489 Gene3D G3DSA:3.30.559.10 34 191 1.3E-7 T 29-03-2018 MSG_RS17350 eb5cc474fd34a783924c4abda4c7ddc8 489 Pfam PF06974 Protein of unknown function (DUF1298) 321 460 2.4E-10 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS17350 eb5cc474fd34a783924c4abda4c7ddc8 489 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 14 464 2.7E-114 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS17350 eb5cc474fd34a783924c4abda4c7ddc8 489 SUPERFAMILY SSF52777 43 177 1.06E-10 T 29-03-2018 MSG_RS17350 eb5cc474fd34a783924c4abda4c7ddc8 489 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 12 282 2.8E-77 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS14915 bc518555e4837fec35a2bda44ecebf30 274 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 14 274 8.6E-111 T 29-03-2018 IPR022292 Conserved hypothetical protein CHP03843 MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 Gene3D G3DSA:3.90.180.10 1 152 3.9E-42 T 29-03-2018 MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 Pfam PF13602 Zinc-binding dehydrogenase 205 308 5.9E-13 T 29-03-2018 MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 100 5.4E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 SMART SM00829 15 308 1.9E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 SUPERFAMILY SSF50129 6 156 2.43E-31 T 29-03-2018 IPR011032 GroES-like MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 SUPERFAMILY SSF51735 120 275 2.88E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01180 6b59b8531b19b82c243b52346034b603 320 Gene3D G3DSA:3.90.180.10 153 309 3.9E-18 T 29-03-2018 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 165 375 1.8E-47 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 163 399 2.6E-79 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 SUPERFAMILY SSF51735 7 104 4.48E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 SUPERFAMILY SSF53790 160 399 2.49E-71 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 Pfam PF13241 Putative NAD(P)-binding 10 114 1.4E-19 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 PIRSF PIRSF036426 3 154 5.9E-28 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 PIRSF PIRSF036426 150 407 3.0E-91 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 Gene3D G3DSA:3.40.1010.10 163 287 2.4E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 Gene3D G3DSA:3.30.950.10 288 403 2.9E-38 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS08495 20c5d2ead6442db5d7a45413fd8008ff 408 Gene3D G3DSA:3.40.50.720 6 129 2.4E-13 T 29-03-2018 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 Pfam PF07969 Amidohydrolase family 59 547 2.7E-50 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 SUPERFAMILY SSF51338 13 66 1.54E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 SUPERFAMILY SSF51338 507 547 1.54E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 Gene3D G3DSA:2.30.40.10 1 90 6.4E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 Gene3D G3DSA:3.20.20.140 194 505 3.6E-39 T 29-03-2018 MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 SUPERFAMILY SSF51556 65 91 9.68E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS07930 3e20b8bbfa9ebae2818218216e329011 551 SUPERFAMILY SSF51556 209 508 9.68E-31 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS11335 90e92043adbec32fc7a852124171749a 404 Pfam PF04229 GrpB protein 211 392 2.5E-42 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase MSG_RS11335 90e92043adbec32fc7a852124171749a 404 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 185 6.0E-41 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MSG_RS11335 90e92043adbec32fc7a852124171749a 404 Pfam PF01121 Dephospho-CoA kinase 4 180 3.3E-60 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MSG_RS11335 90e92043adbec32fc7a852124171749a 404 SUPERFAMILY SSF52540 1 193 1.38E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11335 90e92043adbec32fc7a852124171749a 404 SUPERFAMILY SSF81301 213 397 6.21E-41 T 29-03-2018 MSG_RS11335 90e92043adbec32fc7a852124171749a 404 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.855 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MSG_RS11335 90e92043adbec32fc7a852124171749a 404 Gene3D G3DSA:3.40.50.300 1 194 5.1E-42 T 29-03-2018 MSG_RS11335 90e92043adbec32fc7a852124171749a 404 Gene3D G3DSA:3.30.460.10 206 399 1.2E-55 T 29-03-2018 MSG_RS14220 ac30d436410eddd7eccb2e1138bbb123 380 SUPERFAMILY SSF56112 47 340 3.94E-35 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS14220 ac30d436410eddd7eccb2e1138bbb123 380 Gene3D G3DSA:3.90.1200.10 154 355 1.6E-19 T 29-03-2018 MSG_RS14220 ac30d436410eddd7eccb2e1138bbb123 380 Pfam PF01636 Phosphotransferase enzyme family 107 308 5.4E-15 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS14220 ac30d436410eddd7eccb2e1138bbb123 380 SMART SM00587 141 316 3.9E-4 T 29-03-2018 IPR015897 CHK kinase-like MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 SUPERFAMILY SSF55347 128 328 1.12E-58 T 29-03-2018 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 SMART SM00859 3 118 4.2E-35 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 341 34.549 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 341 1.5E-142 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 SUPERFAMILY SSF51735 2 155 8.2E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 Gene3D G3DSA:3.30.360.10 140 324 4.5E-63 T 29-03-2018 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 PIRSF PIRSF000148 1 345 1.0E-106 T 29-03-2018 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 Gene3D G3DSA:3.40.50.720 1 139 4.6E-32 T 29-03-2018 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 112 2.3E-27 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 242 256 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23395 e68f167e0ae42e49289a9edd6e5ce4ba 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 138 327 3.2E-49 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 13 155 27.325 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 22 149 3.0E-43 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 111 122 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 Gene3D G3DSA:3.30.70.20 57 113 3.2E-17 T 29-03-2018 MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 Gene3D G3DSA:3.30.70.20 114 192 3.9E-8 T 29-03-2018 MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 Pfam PF12838 4Fe-4S dicluster domain 65 125 3.7E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS06725 bd15d7c693370bac93fb116802cb0f1b 197 SUPERFAMILY SSF54862 39 155 7.95E-28 T 29-03-2018 MSG_RS16945 28c5936fabf06265b22ab9a35cbf38bf 566 Pfam PF04174 A circularly permuted ATPgrasp 102 433 6.8E-162 T 29-03-2018 IPR007302 Circularly permuted ATPgrasp domain MSG_RS16945 28c5936fabf06265b22ab9a35cbf38bf 566 PIRSF PIRSF005522 26 505 1.2E-219 T 29-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 MSG_RS16945 28c5936fabf06265b22ab9a35cbf38bf 566 SUPERFAMILY SSF56059 347 492 3.77E-56 T 29-03-2018 MSG_RS16945 28c5936fabf06265b22ab9a35cbf38bf 566 SUPERFAMILY SSF56059 77 240 3.77E-56 T 29-03-2018 MSG_RS16945 28c5936fabf06265b22ab9a35cbf38bf 566 Gene3D G3DSA:3.30.470.20 265 521 8.1E-5 T 29-03-2018 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 Gene3D G3DSA:1.10.10.10 1 55 2.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 SUPERFAMILY SSF46785 3 64 8.99E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 SMART SM00344 4 111 1.8E-41 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.6E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 Gene3D G3DSA:3.30.70.920 57 138 4.9E-17 T 29-03-2018 MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 Pfam PF01037 Lrp/AsnC ligand binding domain 79 140 3.0E-14 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 SUPERFAMILY SSF54909 64 145 8.31E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS16435 05e788ca4146fa3ca3eafe5240ad4f11 148 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 9.1E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS10835 9d0057f4c062730655e348082e6df065 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 21 175 5.0E-53 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS10835 9d0057f4c062730655e348082e6df065 183 SUPERFAMILY SSF51182 1 176 6.75E-60 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS10835 9d0057f4c062730655e348082e6df065 183 Gene3D G3DSA:2.60.120.10 1 180 4.1E-60 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS10835 9d0057f4c062730655e348082e6df065 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 2.3E-56 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS05410 ced265213f375e9c8de2683d6f66534d 435 Gene3D G3DSA:1.20.1250.20 217 410 6.0E-5 T 29-03-2018 MSG_RS05410 ced265213f375e9c8de2683d6f66534d 435 SUPERFAMILY SSF103473 28 403 7.85E-13 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05410 ced265213f375e9c8de2683d6f66534d 435 Gene3D G3DSA:1.20.1250.20 14 216 1.8E-7 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 Gene3D G3DSA:1.20.1250.20 29 221 6.6E-30 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 224 242 1.4E-5 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 425 444 1.4E-5 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 149 1.4E-5 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 Gene3D G3DSA:1.20.1250.20 282 495 4.1E-28 T 29-03-2018 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 37 447 1.5E-122 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 Pfam PF07690 Major Facilitator Superfamily 42 335 6.4E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 SUPERFAMILY SSF103473 271 487 1.44E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05010 c881b6e8c3785c7cc12e3b37cc2a7c37 495 SUPERFAMILY SSF103473 32 216 1.44E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.6E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 Gene3D G3DSA:3.40.50.720 54 259 2.3E-57 T 29-03-2018 MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 1.6E-58 T 29-03-2018 MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 SUPERFAMILY SSF51735 9 253 5.61E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS20490 96cbe6e775110c6629fe407b644d3910 263 Gene3D G3DSA:3.40.50.10090 3 53 1.5E-11 T 29-03-2018 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Gene3D G3DSA:1.10.540.10 1 124 8.5E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 SUPERFAMILY SSF47203 231 390 5.64E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 215 2.0E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Gene3D G3DSA:2.40.110.10 125 223 7.5E-33 T 29-03-2018 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 122 1.7E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 385 2.3E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 Gene3D G3DSA:1.20.140.10 224 392 2.6E-36 T 29-03-2018 MSG_RS22305 4d5346bc08780bc14e7e27fe07a3707b 392 SUPERFAMILY SSF56645 3 244 3.53E-69 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 192 293 8.5E-22 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 SUPERFAMILY SSF55957 418 527 7.19E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 36 171 3.4E-40 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 SUPERFAMILY SSF53738 191 297 1.37E-19 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Gene3D G3DSA:3.40.120.10 196 307 2.6E-23 T 29-03-2018 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 277 292 1.4E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 229 1.4E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 130 144 1.4E-8 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 131 140 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Gene3D G3DSA:3.30.310.50 426 530 2.9E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Gene3D G3DSA:3.40.120.10 308 425 4.3E-35 T 29-03-2018 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 451 502 2.2E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Gene3D G3DSA:3.40.120.10 22 195 1.2E-53 T 29-03-2018 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 305 425 1.5E-18 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 SUPERFAMILY SSF53738 26 171 3.53E-43 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05555 27cf8b5b5953cab1541c01933e1ce16a 531 SUPERFAMILY SSF53738 285 428 4.71E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 Pfam PF00929 Exonuclease 42 208 6.4E-33 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 SUPERFAMILY SSF53098 36 228 2.74E-51 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 Gene3D G3DSA:1.20.5.140 202 220 1.6E-7 T 29-03-2018 MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 SMART SM00479 40 217 4.6E-50 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 Gene3D G3DSA:3.40.1440.10 237 333 1.4E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 Gene3D G3DSA:3.30.420.10 28 201 5.0E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 SUPERFAMILY SSF82771 250 328 1.57E-14 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 35 215 1.8E-25 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS15285 e75f18d47a524af4ea965cd34edecf07 641 SMART SM00465 250 331 1.6E-11 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MSG_RS02380 6c533dae4a3c02ede4645ae613312b45 501 Pfam PF00823 PPE family 8 163 3.3E-61 T 29-03-2018 IPR000030 PPE family MSG_RS02380 6c533dae4a3c02ede4645ae613312b45 501 Gene3D G3DSA:1.10.287.850 24 108 2.4E-5 T 29-03-2018 MSG_RS02380 6c533dae4a3c02ede4645ae613312b45 501 SUPERFAMILY SSF140459 5 177 1.15E-60 T 29-03-2018 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 326 43.9 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 12 324 3.2E-121 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 PIRSF PIRSF000116 2 204 6.8E-40 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 PIRSF PIRSF000116 200 330 1.3E-17 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 181 324 6.8E-62 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 12 175 2.9E-69 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 SUPERFAMILY SSF51735 1 180 1.82E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 Gene3D G3DSA:1.10.1040.10 54 328 5.5E-113 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS07770 5f9dd1b06197e89420e33a2d825e7fae 333 SUPERFAMILY SSF48179 181 326 1.51E-66 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20295 b9447332814fb21f52d474aeca24ad94 220 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 28 184 4.2E-20 T 29-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria MSG_RS16225 84626e772c22b9efc2c30447e8b721fc 456 SUPERFAMILY SSF52777 23 150 6.89E-6 T 29-03-2018 MSG_RS16225 84626e772c22b9efc2c30447e8b721fc 456 Gene3D G3DSA:3.30.559.10 22 182 1.8E-7 T 29-03-2018 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 SUPERFAMILY SSF55681 8 214 1.16E-66 T 29-03-2018 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 PIRSF PIRSF016262 7 224 7.6E-65 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 78 93 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 37 207 2.6E-39 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 Hamap MF_00013 Octanoyltransferase [lipB]. 10 216 33.2 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 82 134 1.0E-20 T 29-03-2018 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 Gene3D G3DSA:3.30.930.10 4 214 3.6E-68 T 29-03-2018 MSG_RS15435 8499b1b17073bd3c0a56ad8e48aa4c6e 232 Pfam PF03099 Biotin/lipoate A/B protein ligase family 68 168 2.0E-8 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MSG_RS23820 d563c26fa5015377173514afacab3e71 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 204 1.3E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS23820 d563c26fa5015377173514afacab3e71 229 Gene3D G3DSA:1.10.3720.10 3 210 5.7E-18 T 29-03-2018 MSG_RS23820 d563c26fa5015377173514afacab3e71 229 SUPERFAMILY SSF161098 14 194 1.19E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Gene3D G3DSA:1.10.8.10 1 55 1.0E-18 T 29-03-2018 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Gene3D G3DSA:1.10.286.20 209 229 6.9E-18 T 29-03-2018 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Pfam PF00889 Elongation factor TS 67 278 1.6E-62 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 SUPERFAMILY SSF46934 5 55 2.41E-14 T 29-03-2018 IPR009060 UBA-like GO:0005515 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 SUPERFAMILY SSF54713 57 88 2.13E-39 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 SUPERFAMILY SSF54713 181 277 2.13E-39 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Gene3D G3DSA:3.30.479.20 153 208 0.0011 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Gene3D G3DSA:3.30.479.20 230 277 6.4E-14 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Gene3D G3DSA:3.30.479.20 56 152 3.5E-19 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 278 9.3E-71 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS08315 d3d2527d0b1f5b2bf4dca306fb7865a5 279 Hamap MF_00050 Elongation factor Ts [tsf]. 1 279 64.112 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 SMART SM01091 339 422 5.6E-19 T 29-03-2018 IPR005170 Transporter-associated domain MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 SUPERFAMILY SSF54631 195 335 1.15E-32 T 29-03-2018 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Gene3D G3DSA:1.20.1250.20 1 124 3.4E-5 T 29-03-2018 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Gene3D G3DSA:3.30.465.10 332 417 2.0E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Pfam PF01595 Domain of unknown function DUF21 10 185 1.6E-32 T 29-03-2018 IPR002550 Domain of unknown function DUF21 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 SUPERFAMILY SSF56176 338 428 2.18E-13 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Gene3D G3DSA:3.10.580.10 181 331 1.1E-33 T 29-03-2018 MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Pfam PF03471 Transporter associated domain 341 402 3.9E-12 T 29-03-2018 IPR005170 Transporter-associated domain MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Pfam PF00571 CBS domain 269 323 4.5E-6 T 29-03-2018 IPR000644 CBS domain MSG_RS16705 d16b85dfe274a2ffb2ba3b8e5fc1d43a 434 Pfam PF00571 CBS domain 206 255 0.0079 T 29-03-2018 IPR000644 CBS domain MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 Pfam PF01612 3'-5' exonuclease 46 197 7.2E-30 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 Gene3D G3DSA:1.10.150.80 225 346 1.1E-26 T 29-03-2018 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 SUPERFAMILY SSF53098 13 239 1.23E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 SUPERFAMILY SSF47819 227 317 8.5E-21 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 SMART SM00341 241 321 9.9E-23 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 Pfam PF00570 HRDC domain 245 310 4.2E-12 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 Gene3D G3DSA:3.30.420.10 20 222 5.4E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS09140 e596d054571bac9b1e90b8c4de5c7acf 431 SMART SM00474 27 198 5.4E-29 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MSG_RS14745 7dd3e94052babef782a470900b03fd17 262 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 234 8.6E-114 T 29-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 MSG_RS14745 7dd3e94052babef782a470900b03fd17 262 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 238 46.851 T 29-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 MSG_RS14745 7dd3e94052babef782a470900b03fd17 262 SUPERFAMILY SSF56235 10 235 7.73E-45 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS14745 7dd3e94052babef782a470900b03fd17 262 Gene3D G3DSA:3.60.20.10 8 241 5.4E-42 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS14745 7dd3e94052babef782a470900b03fd17 262 Pfam PF00227 Proteasome subunit 25 199 1.5E-38 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 Gene3D G3DSA:3.30.280.10 2 99 1.9E-47 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 SUPERFAMILY SSF54111 1 99 8.11E-45 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.42 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.6E-47 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 4.0E-29 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 PIRSF PIRSF001223 1 100 6.8E-50 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12945 c489fffc5bc4f6643215414e4a4f0370 100 Pfam PF00547 Urease, gamma subunit 1 99 2.4E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 Pfam PF16859 Bacterial transcriptional repressor C-terminal 73 186 3.5E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 Gene3D G3DSA:1.10.10.60 6 60 8.1E-15 T 29-03-2018 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 Gene3D G3DSA:1.10.357.10 61 195 4.8E-21 T 29-03-2018 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 SUPERFAMILY SSF46689 7 65 2.1E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01340 cbd468878d920c15e7dc665aa7a12205 195 SUPERFAMILY SSF48498 74 193 7.95E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS03670 d2aa88d5b3a5cd7a744947c8dafd8afd 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 110 1.1E-20 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS03670 d2aa88d5b3a5cd7a744947c8dafd8afd 131 Gene3D G3DSA:2.30.110.10 11 125 6.9E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PIRSF PIRSF001400 2 422 8.2E-187 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 SMART SM01192 138 423 1.1E-206 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 SUPERFAMILY SSF54826 3 137 3.54E-51 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 SUPERFAMILY SSF51604 137 417 6.93E-122 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 418 7.9E-126 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 Gene3D G3DSA:3.20.20.120 127 428 2.4E-100 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 SMART SM01193 4 133 4.7E-87 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 Pfam PF03952 Enolase, N-terminal domain 4 133 2.5E-56 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 Hamap MF_00318 Enolase [eno]. 2 409 45.382 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 ProSitePatterns PS00164 Enolase signature. 332 345 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 37 51 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 361 378 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 332 346 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 106 122 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 160 173 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 PRINTS PR00148 Enolase signature 309 320 2.5E-49 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 Gene3D G3DSA:3.30.390.10 3 126 4.3E-50 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS19845 15599ce9f374938e03fa56fdce04374a 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 4.2E-202 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS08845 188ba86f70b920fc2996782a1d4c4050 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 74 96 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS08845 188ba86f70b920fc2996782a1d4c4050 204 PIRSF PIRSF000847 22 204 1.0E-45 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MSG_RS08845 188ba86f70b920fc2996782a1d4c4050 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 96 4.7E-14 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS08845 188ba86f70b920fc2996782a1d4c4050 204 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 26 198 3.1E-40 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 6 289 22.502 T 29-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 SUPERFAMILY SSF51604 74 285 5.63E-44 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 SMART SM00922 84 181 9.0E-17 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 Gene3D G3DSA:3.30.390.10 11 99 5.1E-39 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 Gene3D G3DSA:3.20.20.120 100 291 8.7E-31 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS03835 83c68de39bff243c458d2462fffb3f2f 326 Pfam PF13378 Enolase C-terminal domain-like 103 268 3.2E-30 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 SUPERFAMILY SSF82114 178 322 1.57E-38 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 SMART SM00904 187 322 1.1E-48 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 Gene3D G3DSA:2.40.30.30 184 324 2.5E-41 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 PIRSF PIRSF004491 2 324 2.1E-95 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 321 8.7E-69 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 Gene3D G3DSA:3.40.50.620 1 183 3.6E-43 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 SUPERFAMILY SSF52374 16 179 2.82E-31 T 29-03-2018 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 Pfam PF06574 FAD synthetase 13 160 7.1E-52 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MSG_RS08620 250ddc325ef3df555d8e40b3af05c84f 324 Pfam PF01687 Riboflavin kinase 188 321 2.7E-33 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 116 127 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 211 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 SUPERFAMILY SSF51735 36 281 3.53E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 Pfam PF00106 short chain dehydrogenase 41 232 3.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 1.7E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 1.7E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 127 1.7E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 59 1.7E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03800 3ba6bb1f35211fda3c94ef148f6d8696 298 Gene3D G3DSA:3.40.50.720 34 296 9.8E-53 T 29-03-2018 MSG_RS01440 8390055e0fedcaa984ad3e64e16f79f2 70 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 69 4.1E-19 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MSG_RS01440 8390055e0fedcaa984ad3e64e16f79f2 70 Gene3D G3DSA:2.40.50.100 1 69 2.9E-19 T 29-03-2018 MSG_RS01440 8390055e0fedcaa984ad3e64e16f79f2 70 SUPERFAMILY SSF50331 1 70 1.99E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS01440 8390055e0fedcaa984ad3e64e16f79f2 70 Pfam PF03459 TOBE domain 4 67 8.7E-16 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MSG_RS04675 55552903ab6f1d3718caa7be7428cb84 221 SUPERFAMILY SSF55729 90 198 5.58E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS04675 55552903ab6f1d3718caa7be7428cb84 221 Gene3D G3DSA:1.10.268.10 1 84 7.6E-9 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS04675 55552903ab6f1d3718caa7be7428cb84 221 Gene3D G3DSA:3.40.630.30 85 215 8.5E-14 T 29-03-2018 MSG_RS04675 55552903ab6f1d3718caa7be7428cb84 221 Pfam PF00583 Acetyltransferase (GNAT) family 145 197 7.1E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 Gene3D G3DSA:3.40.605.10 9 265 1.5E-80 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 Gene3D G3DSA:3.40.309.10 266 461 2.7E-69 T 29-03-2018 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 Pfam PF00171 Aldehyde dehydrogenase family 16 475 1.6E-149 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02715 76cd6324180460aa3434c72d65e1d648 496 SUPERFAMILY SSF53720 14 478 3.01E-146 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS17000 adcaa2ff6a24175c91ce1774af9e457e 278 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 271 1.5E-72 T 29-03-2018 IPR003797 DegV MSG_RS17000 adcaa2ff6a24175c91ce1774af9e457e 278 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 272 6.2E-72 T 29-03-2018 IPR003797 DegV MSG_RS17000 adcaa2ff6a24175c91ce1774af9e457e 278 Gene3D G3DSA:3.30.1180.10 147 273 3.3E-37 T 29-03-2018 MSG_RS17000 adcaa2ff6a24175c91ce1774af9e457e 278 SUPERFAMILY SSF82549 1 271 2.38E-69 T 29-03-2018 MSG_RS17000 adcaa2ff6a24175c91ce1774af9e457e 278 Gene3D G3DSA:3.40.50.10440 2 145 1.8E-40 T 29-03-2018 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 SUPERFAMILY SSF51395 13 189 2.69E-79 T 29-03-2018 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 SUPERFAMILY SSF51395 226 378 2.69E-79 T 29-03-2018 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 TIGRFAM TIGR03966 actino_HemFlav: heme/flavin dehydrogenase, mycofactocin system 3 386 1.2E-215 T 29-03-2018 IPR023989 Heme/flavin dehydrogenase, Rv0694 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 Pfam PF01070 FMN-dependent dehydrogenase 16 376 2.1E-108 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 Gene3D G3DSA:3.20.20.70 7 381 2.1E-89 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS04350 cfcece2e355716b374b6c52f7b7979d3 396 PIRSF PIRSF000138 4 382 7.4E-105 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.3E-9 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.3E-9 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.3E-9 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.3E-9 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 SUPERFAMILY SSF116726 143 203 4.05E-6 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 Gene3D G3DSA:3.40.50.720 1 134 2.5E-21 T 29-03-2018 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 Pfam PF02254 TrkA-N domain 3 116 1.8E-26 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 Gene3D G3DSA:3.30.70.1450 145 216 5.0E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS09095 2dd2bd6f8b2103dbad612cfb72499fcd 227 SUPERFAMILY SSF51735 2 129 2.88E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SMART SM00316 121 188 6.2E-11 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SMART SM00316 207 277 2.4E-28 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SMART SM00316 34 105 3.9E-18 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SMART SM00316 292 363 5.8E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SUPERFAMILY SSF50249 28 130 1.49E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SUPERFAMILY SSF50249 207 289 2.11E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SUPERFAMILY SSF50249 277 365 2.4E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 SUPERFAMILY SSF50249 107 191 2.65E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Gene3D G3DSA:2.40.50.140 13 110 1.6E-18 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Gene3D G3DSA:2.40.50.140 201 283 2.8E-27 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Gene3D G3DSA:2.40.50.140 294 436 1.4E-24 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 102 121 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 307 326 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 143 160 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 346 364 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 172 192 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 126 142 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 36 54 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 54 68 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 PRINTS PR00681 Ribosomal protein S1 signature 229 250 1.9E-88 T 29-03-2018 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Pfam PF00575 S1 RNA binding domain 291 363 1.2E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Pfam PF00575 S1 RNA binding domain 121 188 3.9E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Pfam PF00575 S1 RNA binding domain 33 105 7.3E-17 T 29-03-2018 IPR003029 S1 domain GO:0003676 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Pfam PF00575 S1 RNA binding domain 206 277 2.0E-26 T 29-03-2018 IPR003029 S1 domain GO:0003676 MSG_RS11330 63f044a12a0ebc5f4f3ad1f9e165f49f 480 Gene3D G3DSA:2.40.50.140 120 197 9.6E-12 T 29-03-2018 MSG_RS18610 0a9e157b6ed9b99f35b1654c25f02be6 415 Pfam PF07690 Major Facilitator Superfamily 12 363 3.4E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS18610 0a9e157b6ed9b99f35b1654c25f02be6 415 Gene3D G3DSA:1.20.1250.20 3 204 1.5E-13 T 29-03-2018 MSG_RS18610 0a9e157b6ed9b99f35b1654c25f02be6 415 Gene3D G3DSA:1.20.1250.20 212 409 1.4E-25 T 29-03-2018 MSG_RS18610 0a9e157b6ed9b99f35b1654c25f02be6 415 SUPERFAMILY SSF103473 9 398 5.75E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS14630 4c4328af784ff9a3fc238bb68d672c24 241 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 237 4.6E-67 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 MSG_RS14630 4c4328af784ff9a3fc238bb68d672c24 241 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 240 4.9E-66 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 MSG_RS14630 4c4328af784ff9a3fc238bb68d672c24 241 Gene3D G3DSA:3.40.50.2300 65 239 6.1E-23 T 29-03-2018 MSG_RS13930 ffb42f2a1ac8d44fe4e41c6a4f64491f 312 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 144 156 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site MSG_RS13930 ffb42f2a1ac8d44fe4e41c6a4f64491f 312 Gene3D G3DSA:3.40.50.1820 14 303 4.1E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13930 ffb42f2a1ac8d44fe4e41c6a4f64491f 312 Pfam PF07859 alpha/beta hydrolase fold 80 276 1.5E-23 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS13930 ffb42f2a1ac8d44fe4e41c6a4f64491f 312 SUPERFAMILY SSF53474 17 282 8.67E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 Gene3D G3DSA:1.10.10.60 3 36 9.7E-6 T 29-03-2018 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 SUPERFAMILY SSF46689 72 127 3.69E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 Gene3D G3DSA:1.10.10.60 78 121 4.6E-11 T 29-03-2018 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 Pfam PF00440 Bacterial regulatory proteins, tetR family 77 122 2.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 Gene3D G3DSA:1.10.357.10 122 266 1.8E-13 T 29-03-2018 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 Gene3D G3DSA:1.10.260.40 37 77 3.8E-5 T 29-03-2018 MSG_RS05045 8b4f83cf0c201d2993203fac0e1e40f0 266 SUPERFAMILY SSF48498 141 242 2.18E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 Pfam PF00899 ThiF family 23 258 7.5E-58 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 Gene3D G3DSA:3.40.250.10 277 393 2.0E-27 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 Gene3D G3DSA:3.40.50.720 12 262 1.5E-66 T 29-03-2018 MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 SUPERFAMILY SSF69572 9 363 8.89E-93 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 Pfam PF00581 Rhodanese-like domain 294 387 5.3E-15 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS06255 1eba773df4482f131dfa30d0945ccab5 396 SMART SM00450 294 391 3.6E-24 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS12920 3f753f564b301997deb3639f7d228937 478 SUPERFAMILY SSF54631 93 202 3.41E-16 T 29-03-2018 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 473 2.7E-100 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 SUPERFAMILY SSF51412 202 473 3.92E-93 T 29-03-2018 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 SUPERFAMILY SSF51412 10 93 3.92E-93 T 29-03-2018 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 475 1.4E-268 T 29-03-2018 IPR005991 IMP dehydrogenase-related 1 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 Pfam PF00571 CBS domain 149 202 0.0011 T 29-03-2018 IPR000644 CBS domain MSG_RS12920 3f753f564b301997deb3639f7d228937 478 Pfam PF00571 CBS domain 98 138 7.6E-5 T 29-03-2018 IPR000644 CBS domain MSG_RS12920 3f753f564b301997deb3639f7d228937 478 PIRSF PIRSF000130 2 478 1.9E-146 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 SMART SM01240 11 474 3.5E-183 T 29-03-2018 MSG_RS12920 3f753f564b301997deb3639f7d228937 478 Gene3D G3DSA:3.20.20.70 4 469 2.9E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS15355 b9ab716e73fd164fbe1613a9d4032b52 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MSG_RS15355 b9ab716e73fd164fbe1613a9d4032b52 118 SUPERFAMILY SSF89360 10 105 5.69E-27 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MSG_RS15355 b9ab716e73fd164fbe1613a9d4032b52 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 15 115 2.2E-18 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MSG_RS15355 b9ab716e73fd164fbe1613a9d4032b52 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 5.0E-35 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MSG_RS15355 b9ab716e73fd164fbe1613a9d4032b52 118 Gene3D G3DSA:2.60.300.12 14 118 1.3E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MSG_RS23875 68cc2b5c488515d89631736f042e53d1 226 SUPERFAMILY SSF46689 39 121 1.95E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23875 68cc2b5c488515d89631736f042e53d1 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 50 96 4.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23875 68cc2b5c488515d89631736f042e53d1 226 Gene3D G3DSA:1.10.357.10 96 224 8.6E-11 T 29-03-2018 MSG_RS23875 68cc2b5c488515d89631736f042e53d1 226 Gene3D G3DSA:1.10.10.60 33 95 1.8E-16 T 29-03-2018 MSG_RS06765 773bfd989d50f88f8d546ac3b65422d4 125 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 124 2.7E-34 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06765 773bfd989d50f88f8d546ac3b65422d4 125 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 125 16.936 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 MSG_RS18955 51787591e64d35532ee35ba014e5ae3d 132 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 55 116 1.8E-21 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS18955 51787591e64d35532ee35ba014e5ae3d 132 SUPERFAMILY SSF50249 3 124 2.4E-41 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS18955 51787591e64d35532ee35ba014e5ae3d 132 Gene3D G3DSA:2.40.50.140 57 123 2.8E-18 T 29-03-2018 MSG_RS18955 51787591e64d35532ee35ba014e5ae3d 132 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 53 3.5E-15 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS09130 a63f7eb2e14edadf519303a2f5bc082c 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 2 99 2.9E-19 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 MSG_RS09130 a63f7eb2e14edadf519303a2f5bc082c 105 Gene3D G3DSA:1.10.287.1060 8 100 1.1E-4 T 29-03-2018 MSG_RS23705 be517e5ca3e004c4568f66ac6ea6cbf3 365 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 13 341 1.0E-129 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MSG_RS23705 be517e5ca3e004c4568f66ac6ea6cbf3 365 PIRSF PIRSF005508 4 358 1.0E-131 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MSG_RS23705 be517e5ca3e004c4568f66ac6ea6cbf3 365 Pfam PF01758 Sodium Bile acid symporter family 58 254 6.9E-59 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 Gene3D G3DSA:3.10.129.10 163 284 2.4E-23 T 29-03-2018 MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 SUPERFAMILY SSF54637 166 281 1.29E-26 T 29-03-2018 IPR029069 HotDog domain MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 Pfam PF13452 N-terminal half of MaoC dehydratase 11 139 1.3E-11 T 29-03-2018 MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 Pfam PF01575 MaoC like domain 165 263 1.3E-25 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 Gene3D G3DSA:3.10.129.10 12 162 5.0E-36 T 29-03-2018 MSG_RS22465 8d8b21b45315d3c610798adc121cc2be 286 SUPERFAMILY SSF54637 11 159 2.42E-38 T 29-03-2018 IPR029069 HotDog domain MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 115 16.132 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 Pfam PF00825 Ribonuclease P 2 112 4.6E-25 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 103 2.0E-6 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 SUPERFAMILY SSF54211 2 114 4.05E-22 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 Gene3D G3DSA:3.30.230.10 1 120 3.3E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS24710 dc7b97d012f3c045cd77db6a06d3e1f7 120 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 111 7.3E-22 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SUPERFAMILY SSF46565 8 97 4.19E-28 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 29-03-2018 IPR018253 DnaJ domain, conserved site MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Pfam PF00226 DnaJ domain 10 72 7.9E-25 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Gene3D G3DSA:2.60.260.20 225 282 3.5E-18 T 29-03-2018 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Gene3D G3DSA:2.60.260.20 283 387 6.7E-27 T 29-03-2018 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SUPERFAMILY SSF57938 162 238 1.11E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 389 37.291 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Pfam PF00684 DnaJ central domain 175 235 1.2E-12 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 PRINTS PR00625 DnaJ domain signature 30 45 5.1E-21 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 PRINTS PR00625 DnaJ domain signature 12 30 5.1E-21 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 PRINTS PR00625 DnaJ domain signature 47 67 5.1E-21 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 PRINTS PR00625 DnaJ domain signature 67 86 5.1E-21 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SMART SM00271 9 67 2.0E-26 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SUPERFAMILY SSF49493 141 197 5.49E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SUPERFAMILY SSF49493 241 291 5.49E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Gene3D G3DSA:2.10.230.10 172 224 1.1E-16 T 29-03-2018 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Pfam PF01556 DnaJ C terminal domain 149 360 2.7E-37 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 SUPERFAMILY SSF49493 287 367 6.54E-21 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 Gene3D G3DSA:1.10.287.110 6 143 7.7E-29 T 29-03-2018 IPR001623 DnaJ domain MSG_RS02745 90ba5a7a42cfa771d31deb2243e5f4d7 393 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 377 5.1E-122 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MSG_RS20330 d501bb253f373ec256bf0b5e1359f4d3 292 ProDom PD026943 MEMBRANE ANTIGEN TRANSMEMBRANE ANTIGENIC HOMOLOG PRECURSOR MLCB373.06 SIGNAL 1 172 1.0E-27 T 29-03-2018 IPR035166 Protein of unknown function DUF5336 MSG_RS20330 d501bb253f373ec256bf0b5e1359f4d3 292 Pfam PF17270 Family of unknown function (DUF5336) 8 169 1.2E-58 T 29-03-2018 IPR035166 Protein of unknown function DUF5336 MSG_RS05565 aa67e5995abd0d2a7da5b885e30009e0 202 SUPERFAMILY SSF53474 15 201 1.89E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05565 aa67e5995abd0d2a7da5b885e30009e0 202 Gene3D G3DSA:3.40.50.1820 3 202 4.1E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05565 aa67e5995abd0d2a7da5b885e30009e0 202 Pfam PF01083 Cutinase 16 201 3.2E-40 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS05565 aa67e5995abd0d2a7da5b885e30009e0 202 SMART SM01110 14 202 1.4E-75 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS04055 4cd65c7ae8c68f9be0ff6e2e1a8a45db 240 SUPERFAMILY SSF56281 30 226 1.18E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04055 4cd65c7ae8c68f9be0ff6e2e1a8a45db 240 SMART SM00849 31 206 5.1E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04055 4cd65c7ae8c68f9be0ff6e2e1a8a45db 240 Gene3D G3DSA:3.60.15.10 24 238 9.6E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04055 4cd65c7ae8c68f9be0ff6e2e1a8a45db 240 Pfam PF00753 Metallo-beta-lactamase superfamily 33 206 5.2E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10520 9118c79afbdc8e086159c81e45d3d2b9 304 Pfam PF01040 UbiA prenyltransferase family 31 280 2.8E-61 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MSG_RS10520 9118c79afbdc8e086159c81e45d3d2b9 304 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 18 296 3.5E-97 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MSG_RS10520 9118c79afbdc8e086159c81e45d3d2b9 304 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 297 18.857 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 SUPERFAMILY SSF53067 1 164 1.79E-27 T 29-03-2018 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 Gene3D G3DSA:3.30.420.40 181 340 1.4E-20 T 29-03-2018 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 Pfam PF00012 Hsp70 protein 75 355 2.6E-28 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 Gene3D G3DSA:3.30.420.40 2 180 6.0E-32 T 29-03-2018 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 177 190 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 PRINTS PR00301 70kDa heat shock protein signature 311 327 2.8E-12 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 PRINTS PR00301 70kDa heat shock protein signature 1 14 2.8E-12 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 PRINTS PR00301 70kDa heat shock protein signature 119 139 2.8E-12 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 PRINTS PR00301 70kDa heat shock protein signature 28 40 2.8E-12 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 PRINTS PR00301 70kDa heat shock protein signature 183 193 2.8E-12 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS07235 2ef6744632ab55e4601bf396883ced82 506 SUPERFAMILY SSF53067 171 355 1.57E-25 T 29-03-2018 MSG_RS17685 87b3eb855d3b5594059a85581f030c9f 369 Gene3D G3DSA:3.90.380.10 134 351 1.8E-25 T 29-03-2018 MSG_RS17685 87b3eb855d3b5594059a85581f030c9f 369 SUPERFAMILY SSF55961 148 318 1.1E-19 T 29-03-2018 MSG_RS17685 87b3eb855d3b5594059a85581f030c9f 369 Pfam PF00355 Rieske [2Fe-2S] domain 31 111 3.9E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17685 87b3eb855d3b5594059a85581f030c9f 369 Gene3D G3DSA:2.102.10.10 28 133 3.0E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17685 87b3eb855d3b5594059a85581f030c9f 369 SUPERFAMILY SSF50022 25 137 9.04E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS04515 ec5634f872acd76a305b683c3a880740 312 Pfam PF14494 Domain of unknown function (DUF4436) 44 299 9.5E-94 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 Pfam PF08447 PAS fold 36 121 9.6E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 Gene3D G3DSA:1.10.10.10 142 195 1.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 Pfam PF03861 ANTAR domain 141 192 3.7E-15 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 SUPERFAMILY SSF52172 140 192 8.45E-5 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 SUPERFAMILY SSF55785 24 128 6.63E-14 T 29-03-2018 IPR000014 PAS domain MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 Gene3D G3DSA:3.30.450.20 24 81 6.5E-14 T 29-03-2018 MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 SMART SM01012 138 193 5.5E-17 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS06450 5dd5e48f59fff74cf5885d13d6465d11 228 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 37 129 1.9E-6 T 29-03-2018 IPR000014 PAS domain MSG_RS15485 12f8da0f296ff3e1a072e52a80714985 286 Gene3D G3DSA:3.20.20.30 5 279 1.2E-55 T 29-03-2018 MSG_RS15485 12f8da0f296ff3e1a072e52a80714985 286 SUPERFAMILY SSF51679 7 261 9.71E-53 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS15485 12f8da0f296ff3e1a072e52a80714985 286 Pfam PF00296 Luciferase-like monooxygenase 11 234 1.1E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS15485 12f8da0f296ff3e1a072e52a80714985 286 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 17 254 5.0E-55 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS02095 728e7381553d1fa334b352fe7744790f 311 Pfam PF00268 Ribonucleotide reductase, small chain 28 235 1.3E-16 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS02095 728e7381553d1fa334b352fe7744790f 311 Gene3D G3DSA:1.10.620.20 1 289 2.1E-59 T 29-03-2018 MSG_RS02095 728e7381553d1fa334b352fe7744790f 311 SUPERFAMILY SSF47240 18 286 6.27E-50 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 15 525 34.821 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 SUPERFAMILY SSF53187 198 523 1.07E-106 T 29-03-2018 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 371 378 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 SUPERFAMILY SSF52949 68 177 1.82E-20 T 29-03-2018 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 203 516 2.0E-115 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 PRINTS PR00481 Cytosol aminopeptidase signature 286 303 1.1E-47 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 PRINTS PR00481 Cytosol aminopeptidase signature 308 329 1.1E-47 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 PRINTS PR00481 Cytosol aminopeptidase signature 395 410 1.1E-47 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 PRINTS PR00481 Cytosol aminopeptidase signature 345 366 1.1E-47 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 PRINTS PR00481 Cytosol aminopeptidase signature 367 387 1.1E-47 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 64 163 7.2E-20 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 Gene3D G3DSA:3.40.220.10 13 178 7.7E-27 T 29-03-2018 MSG_RS15400 423aaab8ca075ceef875c302afd14962 527 Gene3D G3DSA:3.40.630.10 187 527 3.2E-129 T 29-03-2018 MSG_RS10500 b6d2da4401026ccdf0f26063d947da7a 303 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 294 3.5E-77 T 29-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA MSG_RS10500 b6d2da4401026ccdf0f26063d947da7a 303 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 302 8.0E-106 T 29-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 Hamap MF_00528 Septum formation protein Maf [maf]. 3 203 27.749 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 Pfam PF02545 Maf-like protein 3 197 1.6E-41 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 197 4.4E-45 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 Gene3D G3DSA:3.90.950.10 2 206 3.6E-59 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 PIRSF PIRSF006305 1 204 1.6E-40 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MSG_RS05690 529046717ca7bf4b32b9fce6d678357b 214 SUPERFAMILY SSF52972 2 197 7.19E-47 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 SUPERFAMILY SSF53474 421 672 7.0E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 SUPERFAMILY SSF50993 14 414 7.85E-53 T 29-03-2018 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 533 553 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 607 629 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 603 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 448 466 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 522 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 499 7.1E-44 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 13 394 7.7E-25 T 29-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 Gene3D G3DSA:3.40.50.1820 403 675 3.7E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 Gene3D G3DSA:2.130.10.120 60 402 1.7E-26 T 29-03-2018 MSG_RS03315 b1c558973cf7a67d6a732b83fe4fad75 676 Pfam PF00326 Prolyl oligopeptidase family 473 674 2.3E-47 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 Pfam PF04542 Sigma-70 region 2 9 71 8.2E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 164 2.5E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 Pfam PF08281 Sigma-70, region 4 110 161 4.4E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 SUPERFAMILY SSF88946 9 83 9.02E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 Gene3D G3DSA:3.10.450.50 154 296 2.6E-14 T 29-03-2018 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 SUPERFAMILY SSF54427 174 293 2.56E-12 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 Gene3D G3DSA:1.10.10.10 72 153 4.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 Gene3D G3DSA:1.10.1740.10 5 71 8.1E-14 T 29-03-2018 MSG_RS05445 89e273ab1d8da0f81017824c9105bbab 302 SUPERFAMILY SSF88659 105 163 4.49E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS21395 3609423efc78db60bb43590420e7f803 412 Gene3D G3DSA:3.90.230.10 153 410 3.6E-44 T 29-03-2018 MSG_RS21395 3609423efc78db60bb43590420e7f803 412 Pfam PF00557 Metallopeptidase family M24 177 396 1.2E-32 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS21395 3609423efc78db60bb43590420e7f803 412 Gene3D G3DSA:3.40.350.10 24 152 3.1E-11 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MSG_RS21395 3609423efc78db60bb43590420e7f803 412 SUPERFAMILY SSF53092 30 164 1.44E-12 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MSG_RS21395 3609423efc78db60bb43590420e7f803 412 SUPERFAMILY SSF55920 169 409 3.14E-47 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS21395 3609423efc78db60bb43590420e7f803 412 Pfam PF01321 Creatinase/Prolidase N-terminal domain 30 165 6.6E-8 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 MSG_RS08600 8dd9f1a011bcabdff9dd693a9cf719e2 260 Pfam PF09851 Short C-terminal domain 231 257 8.8E-8 T 29-03-2018 IPR018649 SHOCT domain MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 SUPERFAMILY SSF56091 17 212 3.29E-44 T 29-03-2018 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 Pfam PF01068 ATP dependent DNA ligase domain 34 211 6.2E-31 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 Pfam PF04679 ATP dependent DNA ligase C terminal region 232 322 3.8E-28 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 SUPERFAMILY SSF50249 214 330 1.46E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 26 328 5.4E-87 T 29-03-2018 IPR014146 DNA ligase D, ligase domain MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 Gene3D G3DSA:2.40.50.140 202 324 1.8E-36 T 29-03-2018 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 44 52 - T 29-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 Gene3D G3DSA:3.30.1490.70 153 201 2.0E-13 T 29-03-2018 MSG_RS11350 ff8fc61717bbbbcaa15dacba2b0d886a 332 Gene3D G3DSA:3.30.470.30 12 152 3.6E-33 T 29-03-2018 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 Gene3D G3DSA:1.10.10.10 20 75 9.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 SUPERFAMILY SSF46785 24 83 8.38E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 Gene3D G3DSA:3.30.70.920 77 161 7.7E-19 T 29-03-2018 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 SMART SM00344 24 133 1.0E-46 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 SUPERFAMILY SSF54909 84 165 3.08E-14 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 8.4E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 8.4E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 40 8.4E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 Pfam PF13412 Winged helix-turn-helix DNA-binding 24 71 9.8E-17 T 29-03-2018 MSG_RS08655 31c8d784e94f577f2a1a90ba12b1afd2 171 Pfam PF01037 Lrp/AsnC ligand binding domain 90 163 8.5E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 SUPERFAMILY SSF53474 2 370 9.81E-108 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 Pfam PF06441 Epoxide hydrolase N terminus 1 106 1.4E-36 T 29-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PRINTS PR00412 Epoxide hydrolase signature 169 182 2.9E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PRINTS PR00412 Epoxide hydrolase signature 124 139 2.9E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PRINTS PR00412 Epoxide hydrolase signature 314 330 2.9E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PRINTS PR00412 Epoxide hydrolase signature 97 115 2.9E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PRINTS PR00412 Epoxide hydrolase signature 345 367 2.9E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 PIRSF PIRSF001112 1 372 3.7E-136 T 29-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 MSG_RS15600 dc2f77d690bded69e4c346d52e2a7d3f 372 Gene3D G3DSA:3.40.50.1820 1 372 8.7E-82 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01695 8524bd3f7a7bd0d5d58fa50e58861cb5 157 SUPERFAMILY SSF54637 15 151 4.75E-32 T 29-03-2018 IPR029069 HotDog domain MSG_RS01695 8524bd3f7a7bd0d5d58fa50e58861cb5 157 Gene3D G3DSA:3.10.129.10 15 153 1.6E-29 T 29-03-2018 MSG_RS01695 8524bd3f7a7bd0d5d58fa50e58861cb5 157 Pfam PF03061 Thioesterase superfamily 32 112 2.1E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS16340 5ac56cecf06debf2f5e463506c3468aa 333 SUPERFAMILY SSF53335 276 320 7.36E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS16340 5ac56cecf06debf2f5e463506c3468aa 333 SUPERFAMILY SSF53335 110 236 7.36E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS16340 5ac56cecf06debf2f5e463506c3468aa 333 Gene3D G3DSA:3.40.50.150 21 326 6.9E-14 T 29-03-2018 MSG_RS16340 5ac56cecf06debf2f5e463506c3468aa 333 Pfam PF08241 Methyltransferase domain 142 224 5.3E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS15020 4b3605a47e03a09bdc1ad8b1d68bcfe8 151 Gene3D G3DSA:1.10.10.10 18 119 7.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS15020 4b3605a47e03a09bdc1ad8b1d68bcfe8 151 SMART SM00347 35 135 2.3E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS15020 4b3605a47e03a09bdc1ad8b1d68bcfe8 151 Pfam PF01047 MarR family 47 100 8.3E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS15020 4b3605a47e03a09bdc1ad8b1d68bcfe8 151 Gene3D G3DSA:1.10.287.100 120 150 1.2E-9 T 29-03-2018 MSG_RS15020 4b3605a47e03a09bdc1ad8b1d68bcfe8 151 SUPERFAMILY SSF46785 10 147 4.62E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Pfam PF01411 tRNA synthetases class II (A) 5 572 1.4E-198 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Gene3D G3DSA:3.30.980.10 570 718 3.9E-38 T 29-03-2018 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 880 7.0E-240 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 670 714 1.4E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 SUPERFAMILY SSF50447 461 569 1.34E-15 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 SMART SM00863 670 714 1.0E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Pfam PF02272 DHHA1 domain 751 897 1.5E-18 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Gene3D G3DSA:3.30.930.10 1 245 2.0E-94 T 29-03-2018 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 SUPERFAMILY SSF55186 569 726 6.8E-41 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 7.2E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 7.2E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 7.2E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 7.2E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 7.2E-27 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 SUPERFAMILY SSF101353 249 444 9.29E-54 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 901 164.622 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MSG_RS09880 33607e14c2849dcb247f12f29825f3fa 904 SUPERFAMILY SSF55681 2 248 5.72E-86 T 29-03-2018 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 Pfam PF01022 Bacterial regulatory protein, arsR family 32 76 2.5E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.0E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 SUPERFAMILY SSF46785 15 103 1.42E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 SMART SM00418 25 103 5.3E-28 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS05995 a11051258c5b988c64e0c8560b255f6b 117 Gene3D G3DSA:1.10.10.10 10 111 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03665 2b84fe3444de9e2e72ce5e9a10c559c4 447 Pfam PF00324 Amino acid permease 16 420 7.1E-106 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MSG_RS03665 2b84fe3444de9e2e72ce5e9a10c559c4 447 PIRSF PIRSF006060 2 446 5.2E-66 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS03665 2b84fe3444de9e2e72ce5e9a10c559c4 447 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 SUPERFAMILY SSF52317 4 204 2.5E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 Pfam PF00117 Glutamine amidotransferase class-I 8 199 2.7E-18 T 29-03-2018 IPR017926 Glutamine amidotransferase MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 PIRSF PIRSF000495 4 206 1.8E-61 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 204 5.1E-67 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 205 31.629 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MSG_RS11170 193463a4ebd8f33d6fffd7eea9f8185e 206 Gene3D G3DSA:3.40.50.880 1 206 4.6E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS07565 17c3305515c1eff5ee2614e4caf7f4a1 338 Gene3D G3DSA:3.90.380.10 140 310 8.4E-4 T 29-03-2018 MSG_RS07565 17c3305515c1eff5ee2614e4caf7f4a1 338 Pfam PF00355 Rieske [2Fe-2S] domain 54 130 4.1E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS07565 17c3305515c1eff5ee2614e4caf7f4a1 338 SUPERFAMILY SSF50022 51 148 5.89E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS07565 17c3305515c1eff5ee2614e4caf7f4a1 338 Gene3D G3DSA:2.102.10.10 40 139 1.6E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 Gene3D G3DSA:1.20.1560.10 21 389 4.0E-78 T 29-03-2018 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 Pfam PF00664 ABC transporter transmembrane region 56 353 2.2E-60 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 Gene3D G3DSA:3.40.50.300 397 642 5.1E-74 T 29-03-2018 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 Pfam PF00005 ABC transporter 425 573 2.1E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 SUPERFAMILY SSF90123 29 72 5.89E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 SUPERFAMILY SSF90123 113 388 5.89E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 SMART SM00382 433 619 6.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18550 e89bfb9a9cc0b9cf5bdeb0697fe55541 642 SUPERFAMILY SSF52540 401 640 4.58E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06870 07f146291655053fd08bc82d2677cddb 328 SUPERFAMILY SSF82689 200 292 1.01E-8 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MSG_RS06870 07f146291655053fd08bc82d2677cddb 328 Pfam PF00924 Mechanosensitive ion channel 89 292 7.7E-40 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MSG_RS06870 07f146291655053fd08bc82d2677cddb 328 Gene3D G3DSA:2.30.30.60 146 200 4.3E-8 T 29-03-2018 MSG_RS06870 07f146291655053fd08bc82d2677cddb 328 Gene3D G3DSA:3.30.70.100 201 298 7.8E-9 T 29-03-2018 MSG_RS06870 07f146291655053fd08bc82d2677cddb 328 SUPERFAMILY SSF50182 131 196 9.48E-11 T 29-03-2018 IPR010920 LSM domain MSG_RS07415 fd6561df5d342329576c051227acf56c 320 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 8 320 4.9E-147 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS07415 fd6561df5d342329576c051227acf56c 320 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 98 114 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07415 fd6561df5d342329576c051227acf56c 320 Pfam PF00268 Ribonucleotide reductase, small chain 10 281 3.3E-90 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07415 fd6561df5d342329576c051227acf56c 320 Gene3D G3DSA:1.10.620.20 1 293 1.5E-80 T 29-03-2018 MSG_RS07415 fd6561df5d342329576c051227acf56c 320 PIRSF PIRSF000355 1 317 3.5E-80 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07415 fd6561df5d342329576c051227acf56c 320 SUPERFAMILY SSF47240 8 320 2.84E-106 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS14375 f838be8b4e400099cb7e6ee216c6dee4 319 SUPERFAMILY SSF52151 5 305 3.14E-43 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS14375 f838be8b4e400099cb7e6ee216c6dee4 319 Gene3D G3DSA:3.40.1090.10 2 213 1.2E-40 T 29-03-2018 MSG_RS14375 f838be8b4e400099cb7e6ee216c6dee4 319 Pfam PF01734 Patatin-like phospholipase 6 205 2.8E-28 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 Gene3D G3DSA:1.10.10.60 2 39 2.4E-11 T 29-03-2018 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 Gene3D G3DSA:1.10.260.40 40 194 7.8E-9 T 29-03-2018 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.1E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00310 5a3eb9e21f6f0de6ff287ce6abc73c90 197 SUPERFAMILY SSF46689 9 65 8.98E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS24205 6d7ce9a0f0b1348e6f8c1132fcb19e8f 630 Pfam PF13641 Glycosyltransferase like family 2 160 418 1.1E-50 T 29-03-2018 MSG_RS24205 6d7ce9a0f0b1348e6f8c1132fcb19e8f 630 SUPERFAMILY SSF53448 335 422 6.84E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS24205 6d7ce9a0f0b1348e6f8c1132fcb19e8f 630 SUPERFAMILY SSF53448 160 293 6.84E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS24205 6d7ce9a0f0b1348e6f8c1132fcb19e8f 630 Gene3D G3DSA:3.90.550.10 150 455 1.8E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 Gene3D G3DSA:3.20.20.70 9 313 3.2E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 TIGRFAM TIGR03962 mycofact_rSAM: mycofactocin radical SAM maturase 11 354 8.1E-198 T 29-03-2018 IPR023913 Mycofactocin, radical SAM peptide maturase MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 SUPERFAMILY SSF102114 21 329 1.7E-59 T 29-03-2018 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 Pfam PF13394 4Fe-4S single cluster domain 31 107 1.2E-4 T 29-03-2018 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 PIRSF PIRSF037420 244 364 4.0E-9 T 29-03-2018 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 PIRSF PIRSF037420 10 237 2.8E-52 T 29-03-2018 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 SMART SM00729 22 221 9.8E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 Pfam PF04055 Radical SAM superfamily 28 182 1.4E-24 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS04345 8f7ba3c4dc880db9b235af196da33074 401 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 253 347 4.0E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain MSG_RS24315 2717336ee2ac006fc8635dddfb2033c1 274 SUPERFAMILY SSF51695 11 264 9.42E-66 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS24315 2717336ee2ac006fc8635dddfb2033c1 274 Gene3D G3DSA:3.20.20.190 2 271 4.2E-67 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS24315 2717336ee2ac006fc8635dddfb2033c1 274 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 258 5.7E-53 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 Gene3D G3DSA:3.40.50.1820 4 287 5.1E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 SUPERFAMILY SSF53474 9 285 2.34E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 1.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 Pfam PF00561 alpha/beta hydrolase fold 36 269 1.6E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00412 Epoxide hydrolase signature 228 244 1.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00412 Epoxide hydrolase signature 62 77 1.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00412 Epoxide hydrolase signature 121 134 1.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00412 Epoxide hydrolase signature 42 60 1.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19400 b1db170856b58f8f8383ba2ba88e2ee4 289 PRINTS PR00412 Epoxide hydrolase signature 261 283 1.6E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS02785 a4e81800161cb143057a5bbffa5a0187 271 Gene3D G3DSA:3.90.226.10 1 267 1.1E-65 T 29-03-2018 MSG_RS02785 a4e81800161cb143057a5bbffa5a0187 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 248 2.0E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS02785 a4e81800161cb143057a5bbffa5a0187 271 SUPERFAMILY SSF52096 5 258 2.19E-60 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS06105 7af35cdef0df182514227feacfa8006c 210 Gene3D G3DSA:1.10.10.60 6 43 7.3E-10 T 29-03-2018 MSG_RS06105 7af35cdef0df182514227feacfa8006c 210 Gene3D G3DSA:1.10.260.40 44 73 1.4E-4 T 29-03-2018 MSG_RS06105 7af35cdef0df182514227feacfa8006c 210 Gene3D G3DSA:1.10.357.10 74 209 2.7E-5 T 29-03-2018 MSG_RS06105 7af35cdef0df182514227feacfa8006c 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 1.5E-4 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06105 7af35cdef0df182514227feacfa8006c 210 SUPERFAMILY SSF46689 10 91 2.87E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 385 1.6E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Gene3D G3DSA:2.40.110.10 137 230 7.5E-35 T 29-03-2018 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Gene3D G3DSA:1.20.140.10 231 392 1.3E-34 T 29-03-2018 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 SUPERFAMILY SSF56645 9 238 1.57E-75 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 SUPERFAMILY SSF47203 244 390 3.06E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 134 1.6E-26 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 228 3.0E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS02920 e3442e648b1927bd5084139bc2d6402a 394 Gene3D G3DSA:1.10.540.10 1 136 1.4E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS11050 30e2b1e3253545970bb54d3c3aae55cf 726 Pfam PF01757 Acyltransferase family 28 369 1.7E-14 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 SUPERFAMILY SSF56425 237 355 2.69E-41 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 Gene3D G3DSA:3.50.50.60 3 426 5.6E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 Gene3D G3DSA:1.20.58.100 427 535 9.9E-34 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 Gene3D G3DSA:4.10.80.40 536 590 3.1E-17 T 29-03-2018 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 5 590 5.4E-304 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 SUPERFAMILY SSF46977 447 590 4.32E-46 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 8 590 7.6E-256 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 SUPERFAMILY SSF51905 359 433 1.18E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 SUPERFAMILY SSF51905 3 260 1.18E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 PIRSF PIRSF000171 1 564 7.6E-46 T 29-03-2018 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 Pfam PF02910 Fumarate reductase flavoprotein C-term 456 590 5.6E-43 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05470 2857b8f4e99c04c4f5f90ba08d5526e5 590 Pfam PF00890 FAD binding domain 8 401 1.2E-111 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 Gene3D G3DSA:1.10.10.10 3 74 3.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 SMART SM00345 18 75 2.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 8.4E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 Gene3D G3DSA:3.40.1410.10 75 243 1.4E-34 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 SUPERFAMILY SSF46785 11 79 3.57E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 SMART SM00866 96 235 2.1E-25 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 4.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 4.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 Pfam PF07702 UTRA domain 100 234 1.0E-29 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS10155 2f65ac70bdcb72572dc4ed60a7246f26 250 SUPERFAMILY SSF64288 63 237 7.54E-36 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS07125 acdb46cf3fdb5c9fea2e322cf33ffce3 204 SUPERFAMILY SSF46689 3 67 5.13E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07125 acdb46cf3fdb5c9fea2e322cf33ffce3 204 SUPERFAMILY SSF48498 82 192 6.08E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS07125 acdb46cf3fdb5c9fea2e322cf33ffce3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.6E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07125 acdb46cf3fdb5c9fea2e322cf33ffce3 204 Gene3D G3DSA:1.10.357.10 65 194 7.3E-30 T 29-03-2018 MSG_RS07125 acdb46cf3fdb5c9fea2e322cf33ffce3 204 Gene3D G3DSA:1.10.10.60 1 61 1.9E-15 T 29-03-2018 MSG_RS04040 d5338d3b1230f29e0629221721327410 339 Pfam PF01734 Patatin-like phospholipase 7 212 8.1E-29 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MSG_RS04040 d5338d3b1230f29e0629221721327410 339 SUPERFAMILY SSF52151 4 328 4.71E-40 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS04040 d5338d3b1230f29e0629221721327410 339 Gene3D G3DSA:3.40.1090.10 2 222 1.2E-36 T 29-03-2018 MSG_RS15010 01a1eac97f1d14f912c503febdc515f8 182 SUPERFAMILY SSF46785 20 143 3.22E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS15010 01a1eac97f1d14f912c503febdc515f8 182 Pfam PF01638 HxlR-like helix-turn-helix 34 133 1.1E-20 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS15010 01a1eac97f1d14f912c503febdc515f8 182 Gene3D G3DSA:1.10.10.10 30 145 5.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12980 2de6b66dad5263bfbfaddd5823abebbb 305 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 11 233 6.2E-90 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c MSG_RS12980 2de6b66dad5263bfbfaddd5823abebbb 305 Pfam PF00296 Luciferase-like monooxygenase 21 243 4.3E-48 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS12980 2de6b66dad5263bfbfaddd5823abebbb 305 SUPERFAMILY SSF51679 3 303 7.72E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS12980 2de6b66dad5263bfbfaddd5823abebbb 305 Gene3D G3DSA:3.20.20.30 1 303 1.8E-67 T 29-03-2018 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 SUPERFAMILY SSF53756 16 398 2.2E-80 T 29-03-2018 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 Pfam PF13439 Glycosyltransferase Family 4 17 197 3.0E-31 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 397 3.6E-198 T 29-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 Pfam PF00534 Glycosyl transferases group 1 205 361 1.6E-31 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 Gene3D G3DSA:3.40.50.2000 208 377 2.2E-41 T 29-03-2018 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 1 401 48.772 T 29-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS03455 30d95065ca037893d289cb8d5bf486cd 428 Gene3D G3DSA:3.40.50.2000 13 207 1.3E-21 T 29-03-2018 MSG_RS03025 5df153c8b2023684407e9150555b1714 69 SUPERFAMILY SSF54285 3 68 2.16E-9 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MSG_RS03025 5df153c8b2023684407e9150555b1714 69 Pfam PF02597 ThiS family 6 69 5.3E-7 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MSG_RS03025 5df153c8b2023684407e9150555b1714 69 Gene3D G3DSA:3.10.20.30 1 69 4.6E-18 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS03025 5df153c8b2023684407e9150555b1714 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 69 5.3E-16 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 SUPERFAMILY SSF55234 84 149 8.5E-27 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PIRSF PIRSF001263 2 150 2.0E-49 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 Gene3D G3DSA:1.10.260.40 2 84 1.7E-9 T 29-03-2018 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 SUPERFAMILY SSF47413 6 80 8.3E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 Hamap MF_00535 Cyanate hydratase [cynS]. 1 158 66.389 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 TIGRFAM TIGR00673 cynS: cyanase 9 147 1.3E-47 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PRINTS PR01693 Cyanase signature 38 55 1.4E-29 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PRINTS PR01693 Cyanase signature 86 100 1.4E-29 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PRINTS PR01693 Cyanase signature 18 33 1.4E-29 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PRINTS PR01693 Cyanase signature 104 120 1.4E-29 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 PRINTS PR01693 Cyanase signature 135 145 1.4E-29 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 Pfam PF02560 Cyanate lyase C-terminal domain 82 148 1.5E-33 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 Gene3D G3DSA:3.30.1160.10 85 149 1.1E-33 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS14345 03e3563c09070c34b430f410a84e014f 158 SMART SM01116 78 149 2.3E-42 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MSG_RS22845 9a5fe3997c8a3efc1429b1cea1eb6602 171 Gene3D G3DSA:3.30.70.560 1 169 9.3E-45 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MSG_RS22845 9a5fe3997c8a3efc1429b1cea1eb6602 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 3.3E-38 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MSG_RS22845 9a5fe3997c8a3efc1429b1cea1eb6602 171 SUPERFAMILY SSF55083 1 141 2.09E-37 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MSG_RS22845 9a5fe3997c8a3efc1429b1cea1eb6602 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MSG_RS22845 9a5fe3997c8a3efc1429b1cea1eb6602 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 1.3E-29 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 SUPERFAMILY SSF102114 154 397 1.31E-56 T 29-03-2018 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 Gene3D G3DSA:3.80.30.20 164 405 2.8E-49 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 21 469 67.34 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 Pfam PF00919 Uncharacterized protein family UPF0004 23 124 2.2E-27 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 SMART SM00729 167 392 9.8E-56 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 171 191 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 22 464 3.4E-147 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 23 457 9.9E-137 T 29-03-2018 MSG_RS08895 6ac28a328037e793358bf35d60e4b3fc 511 Pfam PF04055 Radical SAM superfamily 171 347 1.8E-28 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS12020 cc2751433670111ea413a822bb95d1bd 297 SUPERFAMILY SSF161098 43 283 5.61E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS12020 cc2751433670111ea413a822bb95d1bd 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 286 2.2E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS12020 cc2751433670111ea413a822bb95d1bd 297 Gene3D G3DSA:1.10.3720.10 40 295 4.6E-41 T 29-03-2018 MSG_RS12020 cc2751433670111ea413a822bb95d1bd 297 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 41 288 6.6E-76 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 Pfam PF13519 von Willebrand factor type A domain 99 189 3.1E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 Pfam PF07584 Aerotolerance regulator N-terminal 13 86 1.6E-6 T 29-03-2018 IPR024163 Aerotolerance regulator, N-terminal MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 SMART SM00327 96 299 5.3E-21 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 Hamap MF_01340 UPF0353 protein . 9 335 52.558 T 29-03-2018 IPR022933 Uncharacterised protein family UPF0353 MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 SUPERFAMILY SSF53300 98 297 3.56E-29 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05530 7f52b995bbaf261f18658be8789fbc76 335 Gene3D G3DSA:3.40.50.410 94 308 4.0E-36 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 SMART SM00823 Phosphopantetheine attachment site 643 715 8.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 765 1162 5.1E-89 T 29-03-2018 IPR010080 Thioester reductase-like domain MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:1.10.1200.10 621 719 7.1E-13 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 SUPERFAMILY SSF51735 764 1079 2.86E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 ProSitePatterns PS00455 Putative AMP-binding domain signature. 246 257 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:3.30.300.30 497 620 2.8E-12 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Pfam PF00501 AMP-binding enzyme 84 502 1.1E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:2.30.38.10 420 496 1.7E-10 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 SUPERFAMILY SSF47336 641 725 1.23E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:3.40.50.980 43 248 2.2E-30 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Pfam PF07993 Male sterility protein 768 1030 5.5E-57 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Pfam PF00550 Phosphopantetheine attachment site 648 711 3.8E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:3.40.50.980 249 414 2.4E-34 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 SUPERFAMILY SSF56801 45 630 2.75E-92 T 29-03-2018 MSG_RS09685 17e95d05c036ec9b328494f4161a611b 1163 Gene3D G3DSA:3.40.50.720 760 1105 2.9E-27 T 29-03-2018 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 SUPERFAMILY SSF51905 493 557 1.49E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 SUPERFAMILY SSF51905 3 309 1.49E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 Gene3D G3DSA:4.10.450.10 36 103 1.8E-25 T 29-03-2018 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 Pfam PF05199 GMC oxidoreductase 408 552 5.8E-36 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 PIRSF PIRSF000137 1 558 4.7E-125 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 275 289 - T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 SUPERFAMILY SSF54373 311 494 4.32E-56 T 29-03-2018 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 Gene3D G3DSA:3.30.560.10 104 504 3.3E-86 T 29-03-2018 MSG_RS13750 3332dc54521df0bd44a1d307aff372f9 558 Pfam PF00732 GMC oxidoreductase 4 316 7.1E-70 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS15265 000a962ff686ee3a349dd8b875ae79ea 393 Pfam PF00534 Glycosyl transferases group 1 189 360 4.7E-42 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS15265 000a962ff686ee3a349dd8b875ae79ea 393 Pfam PF13439 Glycosyltransferase Family 4 15 177 4.9E-16 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS15265 000a962ff686ee3a349dd8b875ae79ea 393 Gene3D G3DSA:3.40.50.2000 2 185 2.7E-9 T 29-03-2018 MSG_RS15265 000a962ff686ee3a349dd8b875ae79ea 393 SUPERFAMILY SSF53756 3 379 2.37E-83 T 29-03-2018 MSG_RS15265 000a962ff686ee3a349dd8b875ae79ea 393 Gene3D G3DSA:3.40.50.2000 186 363 3.6E-54 T 29-03-2018 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 271 31.786 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 SMART SM00934 17 261 3.0E-31 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 261 4.9E-81 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 Gene3D G3DSA:3.20.20.70 1 272 9.1E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 SUPERFAMILY SSF51366 6 268 2.97E-57 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS10245 11af9ecf933dba8baf12e7f52def57c7 275 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 260 7.0E-40 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS16040 9ab27fc8f94655178b0f6764cfa96a83 327 SUPERFAMILY SSF53474 17 301 2.12E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16040 9ab27fc8f94655178b0f6764cfa96a83 327 Gene3D G3DSA:3.40.50.1820 5 302 3.4E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16040 9ab27fc8f94655178b0f6764cfa96a83 327 Pfam PF12697 Alpha/beta hydrolase family 43 298 2.9E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 SUPERFAMILY SSF46785 3 86 1.46E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 Gene3D G3DSA:3.40.190.10 177 268 5.6E-13 T 29-03-2018 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 Gene3D G3DSA:3.40.190.10 91 176 1.8E-11 T 29-03-2018 MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 Pfam PF03466 LysR substrate binding domain 88 292 8.5E-26 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 Gene3D G3DSA:1.10.10.10 1 90 2.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02115 8869e3491dcbd07c64c8d248f3131a36 302 SUPERFAMILY SSF53850 88 293 5.12E-25 T 29-03-2018 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 SUPERFAMILY SSF49785 184 323 4.25E-39 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 PIRSF PIRSF016516 2 275 3.3E-87 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 PIRSF PIRSF016516 268 334 3.2E-11 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 TIGRFAM TIGR02961 allantoicase: allantoicase 16 322 2.7E-119 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 Hamap MF_00813 Probable allantoicase [alc]. 5 324 43.881 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 Gene3D G3DSA:2.60.120.260 183 326 7.4E-44 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 Gene3D G3DSA:2.60.120.260 2 177 1.3E-65 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 Pfam PF03561 Allantoicase repeat 24 172 6.4E-49 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 Pfam PF03561 Allantoicase repeat 194 321 2.3E-32 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 MSG_RS14425 e4c796e69762280e49137f832c2e763e 336 SUPERFAMILY SSF49785 10 175 4.25E-55 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS10130 54f80a341b995b6827da7d63e643d285 146 Pfam PF01047 MarR family 38 95 3.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS10130 54f80a341b995b6827da7d63e643d285 146 Gene3D G3DSA:1.10.10.10 25 113 1.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10130 54f80a341b995b6827da7d63e643d285 146 SUPERFAMILY SSF46785 10 144 1.71E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10130 54f80a341b995b6827da7d63e643d285 146 SMART SM00347 31 132 3.8E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS10130 54f80a341b995b6827da7d63e643d285 146 Gene3D G3DSA:1.10.287.100 114 146 9.3E-9 T 29-03-2018 MSG_RS05635 ffaf9b08f463cce0cd0c3e411d569602 313 Gene3D G3DSA:3.40.50.1820 37 313 4.1E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05635 ffaf9b08f463cce0cd0c3e411d569602 313 SUPERFAMILY SSF53474 41 207 2.7E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05635 ffaf9b08f463cce0cd0c3e411d569602 313 SUPERFAMILY SSF53474 263 287 2.7E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05635 ffaf9b08f463cce0cd0c3e411d569602 313 Pfam PF10503 Esterase PHB depolymerase 52 183 3.7E-9 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 SUPERFAMILY SSF56235 1 224 2.92E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 SUPERFAMILY SSF52402 444 569 2.56E-69 T 29-03-2018 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 SUPERFAMILY SSF52402 236 388 2.56E-69 T 29-03-2018 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 PIRSF PIRSF001589 1 592 7.3E-201 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 523 8.3E-129 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 Pfam PF00733 Asparagine synthase 246 589 1.8E-81 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 Pfam PF13537 Glutamine amidotransferase domain 47 166 2.4E-42 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 Gene3D G3DSA:3.40.50.620 223 593 2.3E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 Gene3D G3DSA:3.60.20.10 1 222 5.1E-58 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS04965 c531d6c6b0b389aa2559e209d7ab3ee6 593 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 590 6.6E-280 T 29-03-2018 IPR017535 Asparagine synthase family amidotransferase MSG_RS18440 a251d16682780a4d5851fd413f01adf0 162 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MSG_RS18440 a251d16682780a4d5851fd413f01adf0 162 Gene3D G3DSA:1.10.10.10 1 141 1.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18440 a251d16682780a4d5851fd413f01adf0 162 SUPERFAMILY SSF46785 2 132 4.71E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18440 a251d16682780a4d5851fd413f01adf0 162 Pfam PF02082 Transcriptional regulator 2 83 8.6E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MSG_RS18440 a251d16682780a4d5851fd413f01adf0 162 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 131 1.9E-38 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MSG_RS11115 f1f2344ba7b6fdebf6cc281172bf6075 219 Pfam PF10821 Protein of unknown function (DUF2567) 31 196 6.1E-69 T 29-03-2018 IPR021213 Protein of unknown function DUF2567 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Gene3D G3DSA:1.25.40.10 102 277 1.1E-27 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Gene3D G3DSA:1.10.10.10 1 101 5.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Pfam PF00498 FHA domain 303 365 3.0E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SUPERFAMILY SSF48452 102 271 3.25E-42 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SUPERFAMILY SSF46894 7 98 1.81E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SUPERFAMILY SSF49879 287 374 2.87E-23 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 98 7.3E-10 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Gene3D G3DSA:2.60.200.20 278 380 6.6E-23 T 29-03-2018 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SMART SM00862 20 98 5.5E-11 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SMART SM00240 301 351 7.0E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 SMART SM01043 105 250 5.7E-51 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS18555 6b952953f61abad1ac27561e3d8f8eef 384 Pfam PF03704 Bacterial transcriptional activator domain 105 250 4.4E-46 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 6.0E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 SUPERFAMILY SSF47203 230 374 3.06E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Gene3D G3DSA:1.10.540.10 2 119 9.9E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 370 2.7E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 1.9E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 SUPERFAMILY SSF56645 2 239 7.72E-63 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Gene3D G3DSA:2.40.110.10 120 222 1.2E-27 T 29-03-2018 MSG_RS22585 9fb128f9717a6c841a1c283ce185e6de 381 Gene3D G3DSA:1.20.140.10 223 379 3.3E-36 T 29-03-2018 MSG_RS08125 68c604056d2b38b46355fa28c6b52bed 459 SUPERFAMILY SSF111352 1 405 3.66E-114 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MSG_RS08125 68c604056d2b38b46355fa28c6b52bed 459 Gene3D G3DSA:1.10.3430.10 1 405 4.6E-124 T 29-03-2018 MSG_RS08125 68c604056d2b38b46355fa28c6b52bed 459 Pfam PF00909 Ammonium Transporter Family 1 424 1.4E-131 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MSG_RS08125 68c604056d2b38b46355fa28c6b52bed 459 TIGRFAM TIGR00836 amt: ammonium transporter 1 424 5.5E-141 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MSG_RS08125 68c604056d2b38b46355fa28c6b52bed 459 ProSitePatterns PS01219 Ammonium transporters signature. 174 199 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MSG_RS07800 bf9304fd920a70789a0f841f8330746d 266 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 261 2.7E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS07800 bf9304fd920a70789a0f841f8330746d 266 SUPERFAMILY SSF56529 61 261 1.14E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS07800 bf9304fd920a70789a0f841f8330746d 266 Pfam PF10370 Domain of unknown function (DUF2437) 1 57 2.9E-14 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 MSG_RS07800 bf9304fd920a70789a0f841f8330746d 266 Gene3D G3DSA:3.90.850.10 31 264 7.4E-82 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 SUPERFAMILY SSF51735 7 254 1.38E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 5.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 6.9E-70 T 29-03-2018 MSG_RS13440 c81125819ce3a863d88e3c7d99c6e359 255 Gene3D G3DSA:3.40.50.720 1 255 1.4E-78 T 29-03-2018 MSG_RS13510 4410fc12eee38455994a5f6b5dc3b682 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS13510 4410fc12eee38455994a5f6b5dc3b682 484 Pfam PF00171 Aldehyde dehydrogenase family 16 480 9.0E-163 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS13510 4410fc12eee38455994a5f6b5dc3b682 484 SUPERFAMILY SSF53720 8 483 1.09E-155 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS13510 4410fc12eee38455994a5f6b5dc3b682 484 Gene3D G3DSA:3.40.309.10 272 466 1.7E-70 T 29-03-2018 MSG_RS13510 4410fc12eee38455994a5f6b5dc3b682 484 Gene3D G3DSA:3.40.605.10 1 271 4.7E-88 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SUPERFAMILY SSF158472 183 230 6.54E-8 T 29-03-2018 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SMART SM00388 248 312 7.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SMART SM00304 180 233 9.4E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 466 1.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 Pfam PF00672 HAMP domain 181 230 5.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SUPERFAMILY SSF47384 238 311 1.41E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SMART SM00387 357 469 8.2E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 310 7.1E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 Gene3D G3DSA:3.30.565.10 315 474 9.2E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 Gene3D G3DSA:1.10.287.130 223 308 1.9E-16 T 29-03-2018 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 1.7E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 1.7E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 1.7E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 1.7E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS22060 7eaa53f5ca74cec279612054b5dfcffb 476 SUPERFAMILY SSF55874 301 467 9.95E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23825 60565894446267933bc5c41c3820c17c 367 SUPERFAMILY SSF52540 1 239 5.96E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23825 60565894446267933bc5c41c3820c17c 367 Pfam PF00005 ABC transporter 19 163 3.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS23825 60565894446267933bc5c41c3820c17c 367 SMART SM00382 27 213 2.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS23825 60565894446267933bc5c41c3820c17c 367 SUPERFAMILY SSF54631 278 361 1.93E-7 T 29-03-2018 MSG_RS23825 60565894446267933bc5c41c3820c17c 367 Gene3D G3DSA:3.40.50.300 1 241 7.8E-70 T 29-03-2018 MSG_RS23825 60565894446267933bc5c41c3820c17c 367 Gene3D G3DSA:3.10.580.10 276 367 2.2E-5 T 29-03-2018 MSG_RS23825 60565894446267933bc5c41c3820c17c 367 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 Gene3D G3DSA:3.30.540.10 150 315 3.0E-56 T 29-03-2018 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 Gene3D G3DSA:3.30.540.10 1 149 2.0E-49 T 29-03-2018 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 PIRSF PIRSF004532 1 315 1.3E-147 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 SUPERFAMILY SSF56655 2 307 2.4E-108 T 29-03-2018 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 309 1.7E-106 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MSG_RS19540 18433c62c1e7ae603cf1c646023cf856 328 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 1 304 3.7E-137 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 Gene3D G3DSA:3.40.47.10 280 403 1.9E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 Pfam PF00108 Thiolase, N-terminal domain 6 229 2.9E-46 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 PIRSF PIRSF000429 1 403 3.4E-111 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 Gene3D G3DSA:3.40.47.10 1 279 7.4E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 SUPERFAMILY SSF53901 281 402 4.33E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 401 9.3E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 SUPERFAMILY SSF53901 2 274 1.89E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20955 79a0d80c934ca133b7f6154db900e243 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 4.1E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 SUPERFAMILY SSF53720 2 490 9.29E-156 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 Gene3D G3DSA:3.40.605.10 1 263 7.0E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 490 1.9E-193 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 Gene3D G3DSA:3.40.309.10 264 468 1.8E-64 T 29-03-2018 MSG_RS04750 5470640316eda592d5affbc88d0a3ee4 506 Pfam PF00171 Aldehyde dehydrogenase family 17 486 1.3E-142 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 Gene3D G3DSA:1.10.357.10 62 191 6.0E-11 T 29-03-2018 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 SUPERFAMILY SSF48498 83 174 2.97E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 SUPERFAMILY SSF46689 11 77 4.99E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 Gene3D G3DSA:1.10.10.60 3 61 1.2E-16 T 29-03-2018 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.4E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09440 b4a589bfe653897b35050130c2cac2dd 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS19100 560b1298afa279555a4c2bcba135d452 300 SUPERFAMILY SSF102588 4 293 1.83E-78 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS19100 560b1298afa279555a4c2bcba135d452 300 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 7 292 39.247 T 29-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MSG_RS19100 560b1298afa279555a4c2bcba135d452 300 Gene3D G3DSA:3.40.50.10320 1 299 3.2E-75 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS19100 560b1298afa279555a4c2bcba135d452 300 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 8 292 2.7E-138 T 29-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MSG_RS19100 560b1298afa279555a4c2bcba135d452 300 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 157 1.6E-28 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MSG_RS14950 506b67e203d356576949f5be09b6845a 461 Pfam PF02720 Domain of unknown function (DUF222) 38 361 2.2E-93 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS14950 506b67e203d356576949f5be09b6845a 461 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 5 85 2.0E-18 T 29-03-2018 MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 SUPERFAMILY SSF51430 1 317 1.19E-71 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 Pfam PF00248 Aldo/keto reductase family 15 316 4.3E-56 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 Gene3D G3DSA:3.20.20.100 1 324 6.1E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 PRINTS PR00069 Aldo-keto reductase signature 48 72 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 PRINTS PR00069 Aldo-keto reductase signature 107 125 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 PRINTS PR00069 Aldo-keto reductase signature 139 156 1.9E-6 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS20150 238bca3496263a4887ec6a7e377cf1df 324 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 139 156 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 Pfam PF00083 Sugar (and other) transporter 29 235 1.2E-19 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 Gene3D G3DSA:1.20.1250.20 251 443 2.4E-19 T 29-03-2018 MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 Gene3D G3DSA:1.20.1250.20 22 235 2.3E-24 T 29-03-2018 MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 SUPERFAMILY SSF103473 22 439 3.4E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 Pfam PF07690 Major Facilitator Superfamily 272 436 1.2E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS03655 d952d4a603ff8365f80a0a23a028b8f1 444 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS02100 bb653f4b32b86c0af4002e91bedfbdfc 458 Pfam PF00171 Aldehyde dehydrogenase family 3 455 8.5E-140 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02100 bb653f4b32b86c0af4002e91bedfbdfc 458 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS02100 bb653f4b32b86c0af4002e91bedfbdfc 458 Gene3D G3DSA:3.40.605.10 2 247 2.9E-70 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02100 bb653f4b32b86c0af4002e91bedfbdfc 458 Gene3D G3DSA:3.40.309.10 248 441 2.4E-71 T 29-03-2018 MSG_RS02100 bb653f4b32b86c0af4002e91bedfbdfc 458 SUPERFAMILY SSF53720 3 458 6.02E-144 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 11 479 9.7E-250 T 29-03-2018 IPR014065 tRNA adenylyltransferase MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 193 252 4.1E-17 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 SUPERFAMILY SSF81301 22 163 5.12E-36 T 29-03-2018 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 SUPERFAMILY SSF81891 165 478 1.57E-64 T 29-03-2018 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 Pfam PF01743 Poly A polymerase head domain 39 165 1.3E-35 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 Gene3D G3DSA:1.10.3090.10 163 478 4.0E-66 T 29-03-2018 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 Pfam PF01966 HD domain 268 392 9.4E-15 T 29-03-2018 IPR006674 HD domain MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 SMART SM00471 264 434 9.6E-6 T 29-03-2018 IPR003607 HD/PDEase domain MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 Gene3D G3DSA:3.30.460.10 12 162 3.0E-42 T 29-03-2018 MSG_RS24630 91cb0442caf71564139e148c76a002e4 484 TIGRFAM TIGR00277 HDIG: HDIG domain 265 347 1.3E-19 T 29-03-2018 IPR006675 HDIG domain MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 Gene3D G3DSA:1.20.120.530 76 224 7.2E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 SUPERFAMILY SSF46785 6 77 1.05E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 SMART SM00345 15 73 1.1E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 SUPERFAMILY SSF48008 78 215 7.85E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 SMART SM00895 83 211 8.3E-14 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 Pfam PF07729 FCD domain 84 210 5.3E-21 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 4.0E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS05520 16d3fb545fef3beb4e3da9903ebdce23 227 Gene3D G3DSA:1.10.10.10 1 75 4.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.0E-20 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 SMART SM00662 18 225 9.6E-100 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.587 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 241 302 1.1E-26 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Gene3D G3DSA:1.10.150.20 239 322 3.9E-25 T 29-03-2018 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 SUPERFAMILY SSF56553 48 169 3.14E-42 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 SUPERFAMILY SSF47789 247 318 1.96E-24 T 29-03-2018 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 321 5.0E-35 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 5.4E-115 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Gene3D G3DSA:3.30.1360.10 107 221 1.9E-28 T 29-03-2018 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Gene3D G3DSA:3.30.1360.10 3 84 1.8E-16 T 29-03-2018 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 SUPERFAMILY SSF55257 170 220 4.91E-26 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 SUPERFAMILY SSF55257 15 48 4.91E-26 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS04845 4a0732be87e08e827cedc80aab48eac1 347 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 4.0E-25 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 SUPERFAMILY SSF51905 3 317 4.05E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 313 1.4E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 SUPERFAMILY SSF55424 344 454 1.08E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PIRSF PIRSF000350 2 448 3.2E-89 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 Gene3D G3DSA:3.30.390.30 345 459 2.4E-25 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 2.6E-24 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 2.6E-24 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.6E-24 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 2.6E-24 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 2.6E-24 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 2.3E-44 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 Gene3D G3DSA:3.50.50.60 1 159 8.1E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 Gene3D G3DSA:3.40.50.720 160 331 5.2E-37 T 29-03-2018 MSG_RS14800 15999f01ae226495e08469fc60046d42 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 451 2.0E-20 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 1.1E-7 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 SUPERFAMILY SSF102114 35 296 1.23E-62 T 29-03-2018 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 303 9.1E-101 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 140.177 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 Gene3D G3DSA:3.20.20.70 29 303 8.1E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 Pfam PF04055 Radical SAM superfamily 81 234 1.8E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 PIRSF PIRSF005963 4 313 1.5E-123 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MSG_RS15440 e1ae6f214005e81ebd26382c56898b70 314 SMART SM00729 71 274 6.1E-12 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 SUPERFAMILY SSF46689 4 77 3.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 Gene3D G3DSA:1.10.10.60 1 68 1.7E-17 T 29-03-2018 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 Gene3D G3DSA:1.10.357.10 69 191 1.6E-20 T 29-03-2018 MSG_RS04330 a5c330f8ce207eb0c1914243b160c7a1 197 TIGRFAM TIGR03968 mycofact_TetR: mycofactocin system transcriptional regulator 5 192 1.0E-82 T 29-03-2018 IPR023851 Transcriptional regulator, TetR-type MSG_RS17495 bd3a0493a5e71f1e85180f11e915cc7c 522 Gene3D G3DSA:3.40.50.720 387 510 0.014 T 29-03-2018 MSG_RS17495 bd3a0493a5e71f1e85180f11e915cc7c 522 Pfam PF05872 Bacterial protein of unknown function (DUF853) 37 521 3.9E-177 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal MSG_RS17495 bd3a0493a5e71f1e85180f11e915cc7c 522 Gene3D G3DSA:3.40.50.300 47 386 6.7E-22 T 29-03-2018 MSG_RS17495 bd3a0493a5e71f1e85180f11e915cc7c 522 SUPERFAMILY SSF52540 15 397 2.39E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05570 7289563edeb751f0895457f139794cbb 394 Gene3D G3DSA:3.40.630.10 5 394 8.2E-48 T 29-03-2018 MSG_RS05570 7289563edeb751f0895457f139794cbb 394 PIRSF PIRSF037226 1 393 5.9E-145 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted MSG_RS05570 7289563edeb751f0895457f139794cbb 394 Pfam PF01546 Peptidase family M20/M25/M40 91 346 1.8E-8 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MSG_RS05570 7289563edeb751f0895457f139794cbb 394 SUPERFAMILY SSF55031 173 275 5.06E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS05570 7289563edeb751f0895457f139794cbb 394 Pfam PF07687 Peptidase dimerisation domain 175 258 1.4E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS05570 7289563edeb751f0895457f139794cbb 394 SUPERFAMILY SSF53187 282 375 1.81E-54 T 29-03-2018 MSG_RS05570 7289563edeb751f0895457f139794cbb 394 SUPERFAMILY SSF53187 9 182 1.81E-54 T 29-03-2018 MSG_RS05570 7289563edeb751f0895457f139794cbb 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 350 8.8E-58 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 1 277 3.4E-51 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 SUPERFAMILY SSF55931 1 353 2.16E-91 T 29-03-2018 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 Gene3D G3DSA:3.30.470.20 715 847 9.1E-6 T 29-03-2018 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 1 282 3.2E-80 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 Pfam PF14403 Circularly permuted ATP-grasp type 2 457 836 4.2E-126 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 SUPERFAMILY SSF56059 700 814 1.9E-36 T 29-03-2018 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 SUPERFAMILY SSF56059 433 593 1.9E-36 T 29-03-2018 MSG_RS04960 ca35e909fc40452c49b5a1a286123cff 872 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 407 75.435 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SUPERFAMILY SSF55874 352 522 4.19E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SUPERFAMILY SSF158472 236 286 1.57E-8 T 29-03-2018 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 3.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SMART SM00388 296 363 7.0E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SMART SM00387 409 520 6.9E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SMART SM00304 236 288 6.3E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 518 5.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 Pfam PF00672 HAMP domain 236 284 2.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 Gene3D G3DSA:3.30.565.10 367 528 1.4E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 Pfam PF00512 His Kinase A (phospho-acceptor) domain 297 363 1.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 Gene3D G3DSA:1.10.287.130 283 359 1.7E-14 T 29-03-2018 MSG_RS05910 f08d9c67f20bf1bf75e9800b50f410f7 563 SUPERFAMILY SSF47384 279 363 4.51E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Pfam PF00005 ABC transporter 25 185 2.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Pfam PF00005 ABC transporter 305 456 4.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 268 4.2E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 508 534 8.0E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 SUPERFAMILY SSF52540 4 262 4.69E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 SUPERFAMILY SSF52540 281 528 4.61E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Gene3D G3DSA:3.40.50.300 5 276 4.2E-64 T 29-03-2018 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 Gene3D G3DSA:3.40.50.300 277 537 3.5E-67 T 29-03-2018 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 SMART SM00382 33 234 2.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS23060 b364f07654f6bf1de69f517882bba4de 540 SMART SM00382 313 506 4.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SUPERFAMILY SSF49879 293 379 1.57E-25 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Pfam PF00498 FHA domain 309 372 2.0E-18 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Gene3D G3DSA:1.25.40.10 102 278 4.2E-26 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Gene3D G3DSA:1.10.10.10 1 101 4.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Pfam PF03704 Bacterial transcriptional activator domain 105 250 1.4E-42 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 98 4.6E-12 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SUPERFAMILY SSF48452 100 266 2.0E-38 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SMART SM01043 105 250 1.8E-51 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SMART SM00240 307 357 6.1E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SMART SM00862 20 98 6.3E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 Gene3D G3DSA:2.60.200.20 288 383 5.8E-25 T 29-03-2018 MSG_RS24110 5cb2823674e01fc5bc5bf6cfb97ad0a7 383 SUPERFAMILY SSF46894 9 98 2.52E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS10750 c55887f2ec98e1d778be03aa2d716b16 434 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 228 385 4.3E-6 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 MSG_RS10750 c55887f2ec98e1d778be03aa2d716b16 434 Gene3D G3DSA:3.40.50.2000 257 405 6.2E-28 T 29-03-2018 MSG_RS10750 c55887f2ec98e1d778be03aa2d716b16 434 SUPERFAMILY SSF53756 2 419 3.1E-92 T 29-03-2018 MSG_RS10750 c55887f2ec98e1d778be03aa2d716b16 434 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 99 7.5E-10 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS10750 c55887f2ec98e1d778be03aa2d716b16 434 Gene3D G3DSA:3.40.50.2000 1 256 2.5E-40 T 29-03-2018 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 20 280 42.366 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 Gene3D G3DSA:3.20.20.60 6 280 2.6E-84 T 29-03-2018 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 PIRSF PIRSF000388 11 280 1.4E-114 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 19 280 1.2E-92 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 Pfam PF02548 Ketopantoate hydroxymethyltransferase 19 275 6.2E-107 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MSG_RS15520 ceedd218cbe9ea2e3ac07d23b12d8a6e 280 SUPERFAMILY SSF51621 20 279 1.53E-100 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.5E-51 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.494 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 PIRSF PIRSF002155 1 227 7.2E-71 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 SUPERFAMILY SSF56808 6 226 9.03E-81 T 29-03-2018 IPR023674 Ribosomal protein L1-like MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 Gene3D G3DSA:3.30.190.20 149 228 3.0E-17 T 29-03-2018 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 1.8E-100 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MSG_RS04115 e093681c8ad952ea58337eca1b6d8403 235 Gene3D G3DSA:3.40.50.790 68 148 9.6E-35 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MSG_RS00705 b0750f4557e7f5e6d09c1f204a156073 193 Gene3D G3DSA:3.40.50.740 105 193 1.5E-8 T 29-03-2018 MSG_RS00705 b0750f4557e7f5e6d09c1f204a156073 193 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 49 102 1.1E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS00705 b0750f4557e7f5e6d09c1f204a156073 193 SUPERFAMILY SSF53706 45 193 9.68E-44 T 29-03-2018 MSG_RS00705 b0750f4557e7f5e6d09c1f204a156073 193 Gene3D G3DSA:2.20.25.90 43 104 1.2E-23 T 29-03-2018 MSG_RS00705 b0750f4557e7f5e6d09c1f204a156073 193 SMART SM00926 48 102 1.5E-22 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 23 321 6.0E-119 T 29-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 SUPERFAMILY SSF52540 15 238 1.06E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 Gene3D G3DSA:3.40.50.300 12 276 1.6E-64 T 29-03-2018 MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 SMART SM00382 40 223 2.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS08035 174e35efa17b55081a9444dcc413d016 336 Pfam PF00005 ABC transporter 31 174 5.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 Pfam PF03167 Uracil DNA glycosylase superfamily 55 213 1.1E-17 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 SUPERFAMILY SSF52141 9 226 1.01E-73 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 SMART SM00986 53 214 3.1E-32 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 SMART SM00987 53 214 3.1E-32 T 29-03-2018 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 225 33.895 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 14 218 8.5E-60 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS07880 8ae58a21d0d2d080dd9dd4b4baa323ab 227 Gene3D G3DSA:3.40.470.10 2 227 6.0E-79 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS22340 527175d7e108424223da2099743571cc 96 Pfam PF05360 yiaA/B two helix domain 14 66 7.0E-17 T 29-03-2018 IPR008024 YiaAB two helix MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 Pfam PF00581 Rhodanese-like domain 22 131 8.4E-14 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 Pfam PF00581 Rhodanese-like domain 169 279 3.8E-15 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 Gene3D G3DSA:3.40.250.10 154 294 1.1E-24 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 SUPERFAMILY SSF52821 14 152 3.67E-34 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 SUPERFAMILY SSF52821 163 288 6.81E-33 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 Gene3D G3DSA:3.40.250.10 12 153 2.4E-24 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 ProSitePatterns PS00683 Rhodanese C-terminal signature. 267 277 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 SMART SM00450 158 283 4.2E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 SMART SM00450 21 135 2.9E-17 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS05685 934e0f18a5726f4e225db2c93a70ce89 296 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 5.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 Gene3D G3DSA:1.10.10.60 1 58 5.6E-18 T 29-03-2018 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 Gene3D G3DSA:1.10.357.10 59 196 3.7E-12 T 29-03-2018 MSG_RS24265 b302683e5ddbc9eebf7b3c32bf414784 207 SUPERFAMILY SSF46689 2 65 4.35E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS11825 0f279ff77229fcbf655ab15cca8fab31 251 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 66 230 1.0E-24 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MSG_RS11825 0f279ff77229fcbf655ab15cca8fab31 251 SUPERFAMILY SSF52540 34 250 5.94E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11825 0f279ff77229fcbf655ab15cca8fab31 251 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 37 249 1.9E-76 T 29-03-2018 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 MSG_RS11825 0f279ff77229fcbf655ab15cca8fab31 251 Gene3D G3DSA:3.40.50.300 63 228 3.1E-20 T 29-03-2018 MSG_RS11825 0f279ff77229fcbf655ab15cca8fab31 251 PIRSF PIRSF005624 30 251 2.8E-85 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MSG_RS10810 2e08d0e3019eb91ed07aec6764320fd2 279 Gene3D G3DSA:3.90.25.10 176 275 1.4E-16 T 29-03-2018 MSG_RS10810 2e08d0e3019eb91ed07aec6764320fd2 279 SUPERFAMILY SSF51735 1 264 7.57E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10810 2e08d0e3019eb91ed07aec6764320fd2 279 Gene3D G3DSA:3.40.50.720 1 175 7.2E-23 T 29-03-2018 MSG_RS10810 2e08d0e3019eb91ed07aec6764320fd2 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 229 2.2E-30 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 SUPERFAMILY SSF52402 616 648 5.35E-61 T 29-03-2018 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 SUPERFAMILY SSF52402 324 575 5.35E-61 T 29-03-2018 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 SUPERFAMILY SSF56317 10 296 4.32E-49 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 Pfam PF00795 Carbon-nitrogen hydrolase 13 280 3.5E-16 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 PIRSF PIRSF006630 9 670 8.5E-177 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 Gene3D G3DSA:3.60.110.10 3 354 2.8E-78 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 Pfam PF02540 NAD synthase 347 520 7.3E-23 T 29-03-2018 IPR022310 NAD/GMP synthase MSG_RS17085 6b359cbe84b9c605870b7965857fee19 680 Gene3D G3DSA:3.40.50.620 355 671 8.0E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 491 3.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 1.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 SMART SM00387 382 492 3.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 Gene3D G3DSA:2.60.120.10 10 138 4.9E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 Gene3D G3DSA:3.30.565.10 329 492 1.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 SUPERFAMILY SSF51206 10 132 3.67E-17 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 Gene3D G3DSA:1.10.287.130 149 326 1.1E-4 T 29-03-2018 MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 SUPERFAMILY SSF55874 321 494 4.58E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS04810 a06f050c2c4e4d68cf4bdfdfcd54758c 509 Pfam PF00027 Cyclic nucleotide-binding domain 43 124 1.3E-6 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS24120 aba5286ab50ac1d3f966b9b0aa8c597a 1077 Pfam PF14896 EmbC C-terminal domain 697 1074 1.2E-138 T 29-03-2018 IPR032731 Arabinosyltransferase, C-terminal MSG_RS24120 aba5286ab50ac1d3f966b9b0aa8c597a 1077 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 19 665 2.6E-282 T 29-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 MSG_RS24120 aba5286ab50ac1d3f966b9b0aa8c597a 1077 Gene3D G3DSA:2.60.120.610 41 215 6.6E-61 T 29-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 MSG_RS20200 26c5002cdbd7ab2b451e47f310fa69cb 197 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 186 3.8E-44 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MSG_RS20200 26c5002cdbd7ab2b451e47f310fa69cb 197 PIRSF PIRSF006806 1 189 1.1E-47 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MSG_RS20200 26c5002cdbd7ab2b451e47f310fa69cb 197 Gene3D G3DSA:3.40.50.10420 2 192 7.9E-50 T 29-03-2018 MSG_RS20200 26c5002cdbd7ab2b451e47f310fa69cb 197 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 186 6.7E-37 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MSG_RS20200 26c5002cdbd7ab2b451e47f310fa69cb 197 SUPERFAMILY SSF100950 5 189 1.23E-38 T 29-03-2018 MSG_RS10845 e80c2682e3f586cc83ee1c6442d27807 256 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 1.2E-137 T 29-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 MSG_RS10845 e80c2682e3f586cc83ee1c6442d27807 256 Pfam PF00483 Nucleotidyl transferase 2 201 9.4E-19 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MSG_RS10845 e80c2682e3f586cc83ee1c6442d27807 256 SUPERFAMILY SSF53448 1 249 6.76E-69 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS10845 e80c2682e3f586cc83ee1c6442d27807 256 Gene3D G3DSA:3.90.550.10 1 252 2.1E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS11780 5360a9910ad526c4ba3bff415ba028fa 281 Pfam PF13560 Helix-turn-helix domain 5 84 9.7E-17 T 29-03-2018 MSG_RS11780 5360a9910ad526c4ba3bff415ba028fa 281 SMART SM00530 9 81 8.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS11780 5360a9910ad526c4ba3bff415ba028fa 281 SUPERFAMILY SSF47413 19 78 5.63E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS11780 5360a9910ad526c4ba3bff415ba028fa 281 Gene3D G3DSA:1.10.260.40 2 91 1.4E-16 T 29-03-2018 MSG_RS04795 4abfde535319cfa6908638d093724550 331 SUPERFAMILY SSF51735 1 321 9.23E-88 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04795 4abfde535319cfa6908638d093724550 331 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.8E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04795 4abfde535319cfa6908638d093724550 331 Gene3D G3DSA:3.40.50.720 1 185 1.0E-37 T 29-03-2018 MSG_RS04795 4abfde535319cfa6908638d093724550 331 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 8.6E-146 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MSG_RS04795 4abfde535319cfa6908638d093724550 331 Gene3D G3DSA:3.90.25.10 186 331 7.6E-41 T 29-03-2018 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 208 230 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 357 366 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 105 116 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 366 377 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 335 350 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 168 183 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 290 301 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 307 334 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 PRINTS PR00359 B-class P450 signature 151 167 5.7E-37 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 359 368 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 Pfam PF00067 Cytochrome P450 224 386 3.8E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 SUPERFAMILY SSF48264 12 424 9.69E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21270 3901124bc49d16682c0c5e76a64e7655 426 Gene3D G3DSA:1.10.630.10 3 424 4.7E-62 T 29-03-2018 MSG_RS00020 e8c3fc4687781323bb9e1f72871f89fd 186 Hamap MF_00630 UPF0232 protein . 2 173 35.006 T 29-03-2018 IPR023007 Uncharacterised protein family UPF0232, actinobacteria MSG_RS00020 e8c3fc4687781323bb9e1f72871f89fd 186 Pfam PF05258 Protein of unknown function (DUF721) 74 161 5.7E-24 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 Gene3D G3DSA:1.20.1640.10 707 924 3.6E-29 T 29-03-2018 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 SUPERFAMILY SSF82866 718 927 7.72E-28 T 29-03-2018 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 Pfam PF03176 MMPL family 51 379 5.9E-106 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 Pfam PF03176 MMPL family 600 935 8.8E-102 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 SUPERFAMILY SSF82866 133 350 1.96E-28 T 29-03-2018 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 TIGRFAM TIGR00833 actII: transport protein 17 927 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS17370 d6c836c7cd5a3e7fdc5d0e49bdff4b38 959 Gene3D G3DSA:1.20.1640.10 144 360 3.4E-30 T 29-03-2018 MSG_RS13220 029f597597e9111eb6c183b89dc8e051 183 Pfam PF04264 YceI-like domain 6 177 4.1E-12 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS13220 029f597597e9111eb6c183b89dc8e051 183 SUPERFAMILY SSF101874 6 181 1.31E-20 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS13220 029f597597e9111eb6c183b89dc8e051 183 SMART SM00867 5 180 2.3E-12 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS13220 029f597597e9111eb6c183b89dc8e051 183 Gene3D G3DSA:2.40.128.110 4 183 9.1E-29 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Gene3D G3DSA:2.30.38.10 311 396 1.6E-13 T 29-03-2018 MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Gene3D G3DSA:3.40.50.980 21 161 6.7E-21 T 29-03-2018 MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Pfam PF00501 AMP-binding enzyme 26 403 1.4E-60 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 487 2.1E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Gene3D G3DSA:3.40.50.980 162 310 2.0E-29 T 29-03-2018 MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 SUPERFAMILY SSF56801 23 495 1.96E-108 T 29-03-2018 MSG_RS17745 915b89ed8ba824ccdf59b4446b4f75e2 499 Gene3D G3DSA:3.30.300.30 399 496 1.4E-24 T 29-03-2018 MSG_RS17905 7273c4afe39f26468005aa12def33dc4 137 Gene3D G3DSA:3.30.310.70 1 132 5.2E-35 T 29-03-2018 IPR005180 Domain of unknown function DUF302 MSG_RS17905 7273c4afe39f26468005aa12def33dc4 137 Pfam PF03625 Domain of unknown function DUF302 35 101 4.6E-25 T 29-03-2018 IPR005180 Domain of unknown function DUF302 MSG_RS17905 7273c4afe39f26468005aa12def33dc4 137 SUPERFAMILY SSF103247 5 131 4.19E-35 T 29-03-2018 IPR005180 Domain of unknown function DUF302 MSG_RS17905 7273c4afe39f26468005aa12def33dc4 137 PIRSF PIRSF021774 1 133 3.2E-42 T 29-03-2018 IPR016796 Uncharacterised conserved protein UCP021774 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 PIRSF PIRSF006246 1 132 1.5E-53 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 Gene3D G3DSA:2.40.40.20 1 117 1.0E-53 T 29-03-2018 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 74.464 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 SUPERFAMILY SSF50692 1 115 1.12E-48 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 1.0E-37 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 Pfam PF02261 Aspartate decarboxylase 1 113 1.5E-51 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MSG_RS22820 0ae7580418cdb9a1f467db721bd00012 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 3.5E-51 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 SUPERFAMILY SSF55021 250 330 6.87E-18 T 29-03-2018 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 SUPERFAMILY SSF55021 331 410 2.49E-20 T 29-03-2018 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 PIRSF PIRSF000726 1 62 3.0E-21 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 PIRSF PIRSF000726 57 414 1.0E-124 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Pfam PF01842 ACT domain 268 330 6.9E-10 T 29-03-2018 IPR002912 ACT domain MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Pfam PF13840 ACT domain 341 403 1.0E-12 T 29-03-2018 IPR027795 GATS-like ACT domain MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 406 7.6E-137 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Pfam PF00696 Amino acid kinase family 3 231 5.9E-54 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Gene3D G3DSA:3.40.1160.10 1 235 2.2E-72 T 29-03-2018 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 SUPERFAMILY SSF53633 4 243 2.36E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Gene3D G3DSA:3.30.70.260 333 421 2.2E-19 T 29-03-2018 MSG_RS23400 31f7da0216eadaf1a053aede2e1f4ef9 421 Gene3D G3DSA:3.30.70.260 236 332 2.1E-21 T 29-03-2018 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Gene3D G3DSA:1.20.140.10 568 732 8.6E-31 T 29-03-2018 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Gene3D G3DSA:1.10.540.10 353 471 5.0E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 SUPERFAMILY SSF47203 215 345 2.74E-31 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Gene3D G3DSA:1.10.540.10 1 120 4.7E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 SUPERFAMILY SSF47203 580 728 1.39E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 SUPERFAMILY SSF56645 1 202 8.64E-22 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 99 5.3E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 380 470 7.3E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 SUPERFAMILY SSF56645 366 591 1.96E-56 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Gene3D G3DSA:1.20.140.10 205 342 2.2E-32 T 29-03-2018 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 474 562 1.9E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Gene3D G3DSA:2.40.110.10 472 567 1.1E-30 T 29-03-2018 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 580 726 2.5E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02305 232bdaaa93158f6338484129bf5494af 732 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 341 5.7E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 SUPERFAMILY SSF51735 138 306 1.0E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 SUPERFAMILY SSF50129 1 163 8.7E-48 T 29-03-2018 IPR011032 GroES-like MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 SMART SM00829 8 339 7.5E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 Pfam PF00107 Zinc-binding dehydrogenase 176 300 1.7E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 Gene3D G3DSA:3.90.180.10 1 158 1.3E-45 T 29-03-2018 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 Gene3D G3DSA:3.40.50.10730 159 292 5.9E-18 T 29-03-2018 MSG_RS13270 871291f47661e961f3d9a90619f3121b 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 1.6E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Gene3D G3DSA:3.30.980.10 211 258 3.2E-13 T 29-03-2018 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 213 255 2.6E-11 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 89 685 33.262 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 95 680 5.4E-189 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 SUPERFAMILY SSF55186 88 276 1.09E-50 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Pfam PF03129 Anticodon binding domain 592 681 4.1E-14 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 SUPERFAMILY SSF52954 580 692 8.61E-27 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Gene3D G3DSA:3.30.54.20 167 210 8.0E-15 T 29-03-2018 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Gene3D G3DSA:3.30.980.10 91 166 4.8E-17 T 29-03-2018 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Gene3D G3DSA:3.40.50.800 583 692 2.0E-20 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 PRINTS PR01047 Threonyl-tRNA synthetase signature 379 407 1.5E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 PRINTS PR01047 Threonyl-tRNA synthetase signature 558 571 1.5E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 PRINTS PR01047 Threonyl-tRNA synthetase signature 585 597 1.5E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 PRINTS PR01047 Threonyl-tRNA synthetase signature 412 435 1.5E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 543 1.5E-51 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 374 580 2.7E-34 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 SUPERFAMILY SSF55681 279 576 2.11E-91 T 29-03-2018 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 SMART SM00863 199 255 1.2E-16 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MSG_RS09575 98b3782d0fd18071d17a8b6b20a3cbed 702 Gene3D G3DSA:3.30.930.10 259 582 2.3E-102 T 29-03-2018 MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 Gene3D G3DSA:1.10.1060.10 135 263 3.5E-26 T 29-03-2018 MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 Pfam PF13183 4Fe-4S dicluster domain 174 246 1.1E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 25 139 4.9E-30 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 SUPERFAMILY SSF54292 23 134 2.77E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 SUPERFAMILY SSF46548 135 260 8.55E-33 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 Gene3D G3DSA:3.10.20.30 18 134 5.4E-30 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 176 187 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS05465 a1d4d2db525115f8766fb6f76ad414e6 263 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 28 256 1.7E-72 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 Gene3D G3DSA:3.40.50.1820 67 442 3.5E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 Gene3D G3DSA:3.40.50.980 600 779 1.9E-15 T 29-03-2018 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 Pfam PF00501 AMP-binding enzyme 455 867 1.5E-27 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 SUPERFAMILY SSF56801 442 961 6.28E-47 T 29-03-2018 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 Pfam PF00561 alpha/beta hydrolase fold 124 338 5.7E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 Gene3D G3DSA:3.40.50.980 444 565 1.2E-18 T 29-03-2018 MSG_RS11635 f0cd3d51126ecbd4506d6162b72ccee2 997 SUPERFAMILY SSF53474 52 358 1.05E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Gene3D G3DSA:3.20.20.140 149 431 2.7E-156 T 29-03-2018 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Gene3D G3DSA:3.20.20.140 432 563 1.3E-43 T 29-03-2018 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 577 6.4E-267 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Gene3D G3DSA:2.30.40.10 69 148 2.0E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 ProSitePatterns PS00145 Urease active site. 324 340 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 SUPERFAMILY SSF51556 491 577 6.01E-186 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 SUPERFAMILY SSF51556 136 442 6.01E-186 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 3.3E-52 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Pfam PF01979 Amidohydrolase family 132 463 2.1E-71 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 2.1E-31 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 411 426 2.1E-31 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 2.1E-31 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 437 450 2.1E-31 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 Hamap MF_01953 Urease subunit alpha [ureC]. 2 577 55.569 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 SUPERFAMILY SSF51338 2 183 2.7E-56 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS12955 c3e1be37e949c28e6fc0a5eb70fe72d8 577 SUPERFAMILY SSF51338 419 489 1.14E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS00300 c4743c9dce5add7a29e1066e05f7d7de 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 9.8E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS00300 c4743c9dce5add7a29e1066e05f7d7de 246 SMART SM00345 13 71 1.7E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS00300 c4743c9dce5add7a29e1066e05f7d7de 246 Gene3D G3DSA:1.20.120.530 68 214 6.2E-6 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS00300 c4743c9dce5add7a29e1066e05f7d7de 246 Gene3D G3DSA:1.10.10.10 3 67 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00300 c4743c9dce5add7a29e1066e05f7d7de 246 SUPERFAMILY SSF46785 10 75 8.61E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12405 ef13a1fd9eedceee2a09e9e4ea9ac57d 323 SUPERFAMILY SSF52096 16 253 1.21E-38 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS12405 ef13a1fd9eedceee2a09e9e4ea9ac57d 323 Gene3D G3DSA:3.90.226.10 7 240 8.4E-40 T 29-03-2018 MSG_RS12405 ef13a1fd9eedceee2a09e9e4ea9ac57d 323 Pfam PF00378 Enoyl-CoA hydratase/isomerase 130 257 7.6E-12 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS12405 ef13a1fd9eedceee2a09e9e4ea9ac57d 323 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 82 3.3E-10 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS12060 d68e70ea614baa3347175244155e5468 579 Pfam PF00027 Cyclic nucleotide-binding domain 40 122 3.0E-15 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS12060 d68e70ea614baa3347175244155e5468 579 Pfam PF01734 Patatin-like phospholipase 305 464 2.1E-22 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MSG_RS12060 d68e70ea614baa3347175244155e5468 579 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 308 340 - T 29-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 MSG_RS12060 d68e70ea614baa3347175244155e5468 579 SUPERFAMILY SSF51206 13 139 3.01E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS12060 d68e70ea614baa3347175244155e5468 579 Gene3D G3DSA:3.40.1090.10 296 506 6.5E-38 T 29-03-2018 MSG_RS12060 d68e70ea614baa3347175244155e5468 579 Gene3D G3DSA:2.60.120.10 5 147 1.1E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS12060 d68e70ea614baa3347175244155e5468 579 SMART SM00100 21 135 1.1E-20 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS12060 d68e70ea614baa3347175244155e5468 579 SUPERFAMILY SSF52151 301 568 3.92E-44 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 Gene3D G3DSA:3.40.250.10 4 156 3.8E-30 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 SUPERFAMILY SSF52821 4 151 5.37E-36 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 SMART SM00450 10 135 4.2E-23 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 SMART SM00450 159 277 1.8E-17 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 Gene3D G3DSA:3.40.250.10 162 284 5.0E-23 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 Pfam PF00581 Rhodanese-like domain 165 273 7.0E-9 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 Pfam PF00581 Rhodanese-like domain 11 131 1.5E-17 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 SUPERFAMILY SSF52821 167 283 2.75E-29 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MSG_RS16005 f90f2b232d2baf39cce355b9e29cc111 284 ProSitePatterns PS00683 Rhodanese C-terminal signature. 261 271 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MSG_RS04030 eda55c9404852e17568569902d86429f 465 SUPERFAMILY SSF55424 334 413 3.98E-19 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 Gene3D G3DSA:3.50.50.60 154 335 3.0E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 SUPERFAMILY SSF51905 13 191 2.16E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 295 1.3E-13 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 1.3E-13 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 1.3E-13 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 1.3E-13 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 304 4.9E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.9E-10 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 1.9E-10 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.9E-10 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.9E-10 T 29-03-2018 MSG_RS04030 eda55c9404852e17568569902d86429f 465 Pfam PF14759 Reductase C-terminal 342 411 2.0E-9 T 29-03-2018 IPR028202 Reductase, C-terminal MSG_RS04030 eda55c9404852e17568569902d86429f 465 Gene3D G3DSA:3.30.390.30 338 414 4.2E-16 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 Gene3D G3DSA:3.50.50.60 9 143 6.1E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04030 eda55c9404852e17568569902d86429f 465 SUPERFAMILY SSF51905 151 328 2.69E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13655 0071fc25667cb1853cb50415f5c20ce6 398 Gene3D G3DSA:3.40.50.2000 231 377 2.5E-25 T 29-03-2018 MSG_RS13655 0071fc25667cb1853cb50415f5c20ce6 398 Gene3D G3DSA:3.40.50.2000 1 230 2.5E-29 T 29-03-2018 MSG_RS13655 0071fc25667cb1853cb50415f5c20ce6 398 SUPERFAMILY SSF53756 1 392 7.46E-75 T 29-03-2018 MSG_RS13655 0071fc25667cb1853cb50415f5c20ce6 398 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 52 1.5E-6 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Pfam PF02254 TrkA-N domain 41 94 4.1E-7 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Pfam PF02254 TrkA-N domain 337 427 2.5E-16 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 SUPERFAMILY SSF116726 491 557 1.31E-5 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 SUPERFAMILY SSF51735 333 484 2.44E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Gene3D G3DSA:1.10.287.70 204 318 4.6E-11 T 29-03-2018 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 SUPERFAMILY SSF51735 5 126 1.81E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Pfam PF07885 Ion channel 242 316 6.9E-10 T 29-03-2018 IPR013099 Potassium channel domain MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Gene3D G3DSA:3.40.50.720 328 465 1.2E-19 T 29-03-2018 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Gene3D G3DSA:3.40.50.720 35 99 8.9E-9 T 29-03-2018 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 Gene3D G3DSA:3.30.70.1450 493 567 3.9E-9 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS05335 05e7a0bda80bcbd5db395e658d369ed4 589 SUPERFAMILY SSF81324 211 354 4.71E-18 T 29-03-2018 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 350 173.234 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 Pfam PF00682 HMGL-like 14 272 1.0E-50 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 283 341 9.0E-26 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 14 344 8.9E-153 T 29-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 Gene3D G3DSA:1.10.8.60 289 345 1.8E-25 T 29-03-2018 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 Pfam PF07836 DmpG-like communication domain 281 342 1.9E-27 T 29-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 Gene3D G3DSA:3.20.20.70 13 288 3.0E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 SUPERFAMILY SSF89000 296 345 1.45E-15 T 29-03-2018 MSG_RS22445 0ce2ecaf4a81a8b117a89bc40797cb1b 353 SUPERFAMILY SSF51569 13 276 9.34E-59 T 29-03-2018 MSG_RS08830 b17633607cb59c382365b85da63e36ba 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 71 4.0E-18 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MSG_RS08830 b17633607cb59c382365b85da63e36ba 104 Gene3D G3DSA:3.30.70.100 1 97 1.6E-25 T 29-03-2018 MSG_RS08830 b17633607cb59c382365b85da63e36ba 104 SUPERFAMILY SSF54909 1 94 4.29E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS24570 f34df30baffe02e616b46fac5e9ff4e1 99 Gene3D G3DSA:3.30.1310.10 1 97 3.5E-12 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS24570 f34df30baffe02e616b46fac5e9ff4e1 99 Pfam PF02575 YbaB/EbfC DNA-binding family 16 81 4.8E-8 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS24570 f34df30baffe02e616b46fac5e9ff4e1 99 SUPERFAMILY SSF82607 18 84 2.35E-8 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS00695 d97f50eafce2836fdd890d477c18b781 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 57 2.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00695 d97f50eafce2836fdd890d477c18b781 203 Gene3D G3DSA:1.10.357.10 4 202 5.0E-29 T 29-03-2018 MSG_RS00695 d97f50eafce2836fdd890d477c18b781 203 SUPERFAMILY SSF46689 6 78 5.64E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06165 a185a3aa4042e3f3df81af67a1a243dd 100 Pfam PF13490 Putative zinc-finger 22 55 5.7E-9 T 29-03-2018 IPR027383 Putative zinc-finger MSG_RS06165 a185a3aa4042e3f3df81af67a1a243dd 100 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 21 96 9.3E-31 T 29-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA MSG_RS06165 a185a3aa4042e3f3df81af67a1a243dd 100 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 17 96 1.6E-28 T 29-03-2018 IPR014295 Anti-sigma factor MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 89 111 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 Pfam PF00355 Rieske [2Fe-2S] domain 46 132 1.3E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 SUPERFAMILY SSF50022 24 157 9.17E-44 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 SUPERFAMILY SSF55961 160 379 8.63E-33 T 29-03-2018 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 31 56 2.7E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 2.7E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 2.7E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 61 76 2.7E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 102 122 2.7E-17 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 200 380 4.2E-27 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 Gene3D G3DSA:3.90.380.10 150 386 2.3E-46 T 29-03-2018 MSG_RS10080 195a7e196e0735ea2994fd3417662915 392 Gene3D G3DSA:2.102.10.10 44 149 1.2E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12420 74dace012b93057b85fb7421c37259fd 138 SMART SM00418 3 85 0.0079 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS12420 74dace012b93057b85fb7421c37259fd 138 SUPERFAMILY SSF46785 2 132 9.54E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12420 74dace012b93057b85fb7421c37259fd 138 Gene3D G3DSA:1.10.10.10 1 138 2.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12420 74dace012b93057b85fb7421c37259fd 138 Pfam PF01638 HxlR-like helix-turn-helix 8 95 8.5E-15 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS19305 eb1d813dffcb047141b039b206e9f9fa 588 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 569 9.6E-275 T 29-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 SUPERFAMILY SSF52402 7 146 6.03E-22 T 29-03-2018 MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 Pfam PF00582 Universal stress protein family 7 141 3.2E-17 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 Pfam PF00582 Universal stress protein family 154 281 8.1E-8 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 Gene3D G3DSA:3.40.50.620 2 141 2.8E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 PRINTS PR01438 Universal stress protein signature 243 255 3.3E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 PRINTS PR01438 Universal stress protein signature 260 282 3.3E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 PRINTS PR01438 Universal stress protein signature 7 25 3.3E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 SUPERFAMILY SSF52402 154 282 1.84E-12 T 29-03-2018 MSG_RS13900 bac00162fc1c173c551c79c9ad69261d 286 Gene3D G3DSA:3.40.50.620 142 282 3.4E-13 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS17655 076c620e7cd6980253f4b43c5430fe85 444 Gene3D G3DSA:2.40.370.10 232 373 1.1E-20 T 29-03-2018 IPR023374 AttH-like domain MSG_RS17655 076c620e7cd6980253f4b43c5430fe85 444 Gene3D G3DSA:2.40.370.10 21 223 1.6E-21 T 29-03-2018 IPR023374 AttH-like domain MSG_RS17655 076c620e7cd6980253f4b43c5430fe85 444 SUPERFAMILY SSF159245 10 370 1.7E-41 T 29-03-2018 MSG_RS10185 f67c6ab67ce84e5671123bd7eca506b1 179 Pfam PF13302 Acetyltransferase (GNAT) domain 14 149 1.8E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS10185 f67c6ab67ce84e5671123bd7eca506b1 179 SUPERFAMILY SSF55729 6 175 2.86E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS10185 f67c6ab67ce84e5671123bd7eca506b1 179 Gene3D G3DSA:3.40.630.30 2 177 3.5E-27 T 29-03-2018 MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 SUPERFAMILY SSF53850 544 609 3.26E-56 T 29-03-2018 MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 SUPERFAMILY SSF53850 55 498 3.26E-56 T 29-03-2018 MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 107 476 4.6E-35 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 Gene3D G3DSA:3.90.76.10 90 185 2.9E-15 T 29-03-2018 MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 Gene3D G3DSA:3.10.105.10 320 593 1.2E-37 T 29-03-2018 MSG_RS19110 6b24e92289ac3f2e1006c5ecf8fe7907 628 Gene3D G3DSA:3.40.190.10 186 319 1.2E-21 T 29-03-2018 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 PRINTS PR00412 Epoxide hydrolase signature 228 244 1.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 PRINTS PR00412 Epoxide hydrolase signature 260 282 1.2E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 Pfam PF00561 alpha/beta hydrolase fold 27 268 4.8E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 Gene3D G3DSA:3.40.50.1820 3 288 1.9E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21850 aac0a5a85d2502cbfbd246ebdb4541b8 289 SUPERFAMILY SSF53474 4 284 9.85E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 3.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 Gene3D G3DSA:1.10.357.10 69 205 6.5E-9 T 29-03-2018 MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 Gene3D G3DSA:1.10.10.60 3 68 1.8E-17 T 29-03-2018 MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS12290 b66e3a8b371a4aa653b002b4016f4b01 205 SUPERFAMILY SSF46689 12 94 5.99E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21930 ec2a7c8f2907aaff06f873169a2c762d 234 Gene3D G3DSA:3.20.20.370 18 219 5.1E-8 T 29-03-2018 MSG_RS21930 ec2a7c8f2907aaff06f873169a2c762d 234 SUPERFAMILY SSF88713 26 143 2.72E-7 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS21930 ec2a7c8f2907aaff06f873169a2c762d 234 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 14 138 1.5E-18 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SMART SM00267 857 1035 9.2E-23 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SMART SM00267 326 497 1.0E-50 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Pfam PF00990 Diguanylate cyclase, GGDEF domain 337 491 6.8E-39 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Pfam PF00990 Diguanylate cyclase, GGDEF domain 868 1026 1.6E-25 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 866 1026 3.7E-19 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 335 492 9.1E-34 T 29-03-2018 IPR000160 GGDEF domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Pfam PF00563 EAL domain 1052 1285 1.2E-61 T 29-03-2018 IPR001633 EAL domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SUPERFAMILY SSF55073 342 495 6.12E-41 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SUPERFAMILY SSF141868 1053 1298 1.44E-71 T 29-03-2018 IPR001633 EAL domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Gene3D G3DSA:3.30.70.270 325 500 4.5E-51 T 29-03-2018 MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SMART SM00052 1045 1290 6.7E-74 T 29-03-2018 IPR001633 EAL domain MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 SUPERFAMILY SSF55073 900 1026 5.02E-25 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Gene3D G3DSA:3.30.70.270 862 1040 4.8E-34 T 29-03-2018 MSG_RS18590 929cd4a9d96daacc53b710edbe9c8fb9 1314 Gene3D G3DSA:3.20.20.450 1041 1294 5.4E-79 T 29-03-2018 IPR001633 EAL domain MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 Gene3D G3DSA:1.10.645.10 1 212 1.8E-47 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 412 421 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 Pfam PF00374 Nickel-dependent hydrogenase 43 128 2.0E-14 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 Pfam PF00374 Nickel-dependent hydrogenase 333 421 9.1E-9 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 SUPERFAMILY SSF56762 7 421 1.2E-88 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14140 e60e5b4667f7c628a3dfd3d4aa648a53 430 Gene3D G3DSA:1.10.645.10 213 421 6.5E-34 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 Gene3D G3DSA:2.60.40.1180 522 573 3.6E-5 T 29-03-2018 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 SUPERFAMILY SSF81296 2 76 1.0E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 SMART SM00642 99 444 2.4E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 PIRSF PIRSF006337 1 573 4.8E-234 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 2 542 3.2E-235 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 Pfam PF11941 Domain of unknown function (DUF3459) 488 570 1.5E-18 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 Pfam PF00128 Alpha amylase, catalytic domain 109 202 1.3E-14 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 Gene3D G3DSA:2.60.40.10 1 77 2.5E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 Gene3D G3DSA:3.20.20.80 88 504 3.9E-76 T 29-03-2018 MSG_RS11035 c2075310c180c4e800ff89710fc49f24 574 SUPERFAMILY SSF51445 75 502 4.7E-103 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS14370 908edd3873469c94f4d305ba649a27bb 277 Pfam PF11296 Protein of unknown function (DUF3097) 4 274 1.0E-117 T 29-03-2018 IPR021447 Protein of unknown function DUF3097 MSG_RS22395 acb57ea4c1448918ad917c5292e644f2 354 SUPERFAMILY SSF53901 228 342 3.27E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22395 acb57ea4c1448918ad917c5292e644f2 354 Gene3D G3DSA:3.40.47.10 216 314 1.1E-7 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22395 acb57ea4c1448918ad917c5292e644f2 354 SUPERFAMILY SSF53901 3 224 3.3E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22395 acb57ea4c1448918ad917c5292e644f2 354 Gene3D G3DSA:3.40.47.10 3 215 1.4E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS12960 c18d2b7de0b8d8ac2368e1a8f63b3d56 211 Pfam PF01730 UreF 37 172 1.9E-14 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MSG_RS12960 c18d2b7de0b8d8ac2368e1a8f63b3d56 211 PIRSF PIRSF009467 1 211 2.5E-38 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MSG_RS02335 5926dabe6e4748ced7479a938dbc7d7e 219 SUPERFAMILY SSF46689 16 90 4.72E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02335 5926dabe6e4748ced7479a938dbc7d7e 219 Gene3D G3DSA:1.10.260.40 52 76 5.1E-5 T 29-03-2018 MSG_RS02335 5926dabe6e4748ced7479a938dbc7d7e 219 Gene3D G3DSA:1.10.10.60 12 51 2.8E-10 T 29-03-2018 MSG_RS02335 5926dabe6e4748ced7479a938dbc7d7e 219 Gene3D G3DSA:1.10.357.10 77 202 1.6E-8 T 29-03-2018 MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 Gene3D G3DSA:3.40.50.1820 97 512 1.5E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 Pfam PF00561 alpha/beta hydrolase fold 152 304 3.4E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 SUPERFAMILY SSF53474 117 171 4.06E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 SUPERFAMILY SSF53474 347 490 4.06E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 SUPERFAMILY SSF53474 216 270 4.06E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09190 2a247d33c8c2788970eed0d6e1ea1e04 519 Pfam PF08386 TAP-like protein 416 517 5.8E-18 T 29-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal MSG_RS05960 eec3ac00da196d2d3593e697c283fb59 286 PIRSF PIRSF028756 2 281 2.3E-127 T 29-03-2018 IPR016898 Polyphosphate kinase 2 MSG_RS05960 eec3ac00da196d2d3593e697c283fb59 286 SUPERFAMILY SSF52540 56 243 3.97E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS05960 eec3ac00da196d2d3593e697c283fb59 286 Gene3D G3DSA:3.40.50.300 3 268 7.4E-98 T 29-03-2018 MSG_RS05960 eec3ac00da196d2d3593e697c283fb59 286 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 25 251 8.2E-110 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related MSG_RS05960 eec3ac00da196d2d3593e697c283fb59 286 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 24 251 2.5E-113 T 29-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 SUPERFAMILY SSF50129 1 137 9.13E-36 T 29-03-2018 IPR011032 GroES-like MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 SUPERFAMILY SSF51735 111 273 1.3E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 4.5E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 SMART SM00829 10 323 1.3E-18 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 Gene3D G3DSA:3.90.180.10 1 132 1.4E-37 T 29-03-2018 MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 Gene3D G3DSA:3.40.50.720 133 293 1.2E-28 T 29-03-2018 MSG_RS10525 8696f6f465d7ab1c49e56f496d4edc54 325 Pfam PF00107 Zinc-binding dehydrogenase 150 255 8.5E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 Gene3D G3DSA:3.40.50.2300 7 132 2.0E-39 T 29-03-2018 MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 SUPERFAMILY SSF52172 10 184 5.13E-41 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 Pfam PF00072 Response regulator receiver domain 13 123 2.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 SMART SM00862 158 233 8.1E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 SMART SM00448 11 122 1.8E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 Gene3D G3DSA:1.10.10.10 133 236 4.7E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20655 547106c3d657029832665b8bb2678ccd 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 233 1.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 PIRSF PIRSF002161 4 187 3.3E-63 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 Pfam PF00281 Ribosomal protein L5 31 87 2.6E-25 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 Gene3D G3DSA:3.30.1440.10 8 186 2.0E-72 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 6.3E-38 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 43.104 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04565 a9dabd54a2b68d18e5502cdd71453014 187 SUPERFAMILY SSF55282 10 185 4.71E-73 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS08955 709d6bedaa5c908db72ca6acea03a15d 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 7.4E-48 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MSG_RS08955 709d6bedaa5c908db72ca6acea03a15d 154 Pfam PF03477 ATP cone domain 47 131 1.9E-13 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MSG_RS08955 709d6bedaa5c908db72ca6acea03a15d 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 78.136 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 SMART SM00448 13 124 6.3E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 SUPERFAMILY SSF46894 138 236 1.25E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 Pfam PF00072 Response regulator receiver domain 15 124 4.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 SMART SM00862 161 235 1.4E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 SUPERFAMILY SSF52172 7 132 2.42E-42 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS22065 933ef8f466670213a54726b3928963a9 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 235 4.6E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 Gene3D G3DSA:3.40.50.2300 2 135 1.4E-37 T 29-03-2018 MSG_RS22065 933ef8f466670213a54726b3928963a9 239 Gene3D G3DSA:1.10.10.10 136 239 3.8E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21320 7fe7bacc6a9c037739aa3f3414a142f7 407 SUPERFAMILY SSF51338 343 403 3.65E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS21320 7fe7bacc6a9c037739aa3f3414a142f7 407 Gene3D G3DSA:3.20.20.140 91 364 4.2E-45 T 29-03-2018 MSG_RS21320 7fe7bacc6a9c037739aa3f3414a142f7 407 Pfam PF01979 Amidohydrolase family 49 400 2.4E-33 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS21320 7fe7bacc6a9c037739aa3f3414a142f7 407 Gene3D G3DSA:2.30.40.10 3 90 1.2E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS21320 7fe7bacc6a9c037739aa3f3414a142f7 407 SUPERFAMILY SSF51556 53 362 3.1E-91 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS01165 8032b2a75d4d943206db1a92616cfdc9 219 SUPERFAMILY SSF53335 40 193 1.62E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01165 8032b2a75d4d943206db1a92616cfdc9 219 Pfam PF13578 Methyltransferase domain 76 178 3.8E-14 T 29-03-2018 MSG_RS01165 8032b2a75d4d943206db1a92616cfdc9 219 Gene3D G3DSA:3.40.50.150 40 213 1.2E-27 T 29-03-2018 MSG_RS18065 c5b25d6195d82747d9ec9980fe790c3d 199 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 45.892 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 MSG_RS18065 c5b25d6195d82747d9ec9980fe790c3d 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 194 1.8E-44 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MSG_RS18065 c5b25d6195d82747d9ec9980fe790c3d 199 SUPERFAMILY SSF52972 2 196 1.31E-59 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MSG_RS18065 c5b25d6195d82747d9ec9980fe790c3d 199 Pfam PF01725 Ham1 family 4 192 4.9E-52 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MSG_RS18065 c5b25d6195d82747d9ec9980fe790c3d 199 Gene3D G3DSA:3.90.950.10 1 199 3.5E-72 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MSG_RS12690 751d2ed2f409be73f88eff7bd0556b39 503 PIRSF PIRSF017804 16 503 1.9E-49 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS12690 751d2ed2f409be73f88eff7bd0556b39 503 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 23 502 2.1E-111 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS12690 751d2ed2f409be73f88eff7bd0556b39 503 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 23 103 6.2E-12 T 29-03-2018 IPR024962 YukD-like MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 6 761 34.402 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 434 756 2.7E-151 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 8 315 2.3E-111 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 11 760 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 Gene3D G3DSA:3.20.20.210 6 393 7.2E-133 T 29-03-2018 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 PIRSF PIRSF000382 5 762 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 SUPERFAMILY SSF51726 417 759 1.44E-112 T 29-03-2018 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 Gene3D G3DSA:3.20.20.210 394 761 2.6E-120 T 29-03-2018 MSG_RS19300 52cb71862cf607efeed03a5a459b1eb4 762 SUPERFAMILY SSF51726 8 398 1.31E-93 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 452 2.3E-25 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Gene3D G3DSA:3.30.390.30 337 462 9.1E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 SUPERFAMILY SSF51905 1 334 2.59E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PIRSF PIRSF000350 1 465 2.5E-70 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 3.2E-57 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.5E-31 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 3.5E-31 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 3.5E-31 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.5E-31 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.5E-31 T 29-03-2018 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 SUPERFAMILY SSF55424 343 462 1.03E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 325 5.8E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Gene3D G3DSA:3.50.50.60 275 336 2.6E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Gene3D G3DSA:3.50.50.60 1 163 4.4E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08985 c1740de412335ee54243adf04e4e2d09 468 Gene3D G3DSA:3.50.50.60 164 274 4.0E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 107 139 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 Gene3D G3DSA:3.30.950.10 373 493 7.5E-50 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 Gene3D G3DSA:3.40.1010.10 253 372 1.2E-29 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 Gene3D G3DSA:3.40.1010.10 8 160 3.8E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 256 495 2.2E-81 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 SUPERFAMILY SSF53790 6 242 1.83E-42 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 SUPERFAMILY SSF53790 252 481 4.45E-49 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 9 240 2.6E-66 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 256 460 2.6E-33 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS14615 656e8e0694a0b2d677209fd5065f93bd 497 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 223 2.4E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 SUPERFAMILY SSF53323 28 246 2.22E-16 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 34 222 6.3E-25 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 25 615 4.2E-200 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 523 618 1.3E-7 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 SUPERFAMILY SSF52518 246 506 3.66E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 SUPERFAMILY SSF52922 521 624 4.24E-16 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Gene3D G3DSA:3.40.50.920 519 634 3.3E-8 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 273 483 2.1E-58 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Gene3D G3DSA:3.40.920.10 23 240 6.6E-39 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MSG_RS17200 f2b550b69dda5ff1a50a2c8c975dbba3 650 Gene3D G3DSA:3.40.50.970 245 507 3.7E-56 T 29-03-2018 MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 Pfam PF00106 short chain dehydrogenase 16 216 2.3E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 Gene3D G3DSA:3.40.50.720 1 303 4.8E-58 T 29-03-2018 MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 SUPERFAMILY SSF51735 13 262 2.52E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 6.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 6.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 9.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 9.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03210 9bff97f216a718528d12ddd24076dbf4 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 9.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23540 2aa7765c7ec3ecd79afeaf9214c1858d 456 Pfam PF12770 CHAT domain 107 391 4.6E-11 T 29-03-2018 IPR024983 CHAT domain MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 PIRSF PIRSF006769 3 266 3.1E-91 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 PIRSF PIRSF006769 250 339 3.0E-12 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 Gene3D G3DSA:3.40.140.10 1 150 2.0E-27 T 29-03-2018 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 SUPERFAMILY SSF53597 150 333 1.81E-46 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 12 333 3.0E-94 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 105 1.0E-14 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 Pfam PF01872 RibD C-terminal domain 153 333 1.8E-48 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 SUPERFAMILY SSF53927 10 138 4.21E-37 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 Gene3D G3DSA:3.40.430.10 151 340 3.1E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS10340 1b619b90a4c05de5015cdffd83026f0d 340 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 94 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 SUPERFAMILY SSF52440 6 150 2.01E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 118 129 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 SUPERFAMILY SSF56059 151 366 8.93E-55 T 29-03-2018 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Gene3D G3DSA:3.30.470.20 221 370 3.9E-41 T 29-03-2018 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 7 366 40.956 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Gene3D G3DSA:3.30.1490.20 147 220 1.4E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Pfam PF01820 D-ala D-ala ligase N-terminus 8 140 2.4E-29 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 365 1.9E-112 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 309 336 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Pfam PF07478 D-ala D-ala ligase C-terminus 159 363 4.0E-72 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 PIRSF PIRSF039102 4 370 3.7E-107 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS07865 2b1e17d2982daf6352f692d5eb6e114a 373 Gene3D G3DSA:3.40.50.20 1 146 2.8E-45 T 29-03-2018 MSG_RS15345 4df92cded8ef2a2099d88b597b26fa5f 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 6.6E-52 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MSG_RS15345 4df92cded8ef2a2099d88b597b26fa5f 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MSG_RS15345 4df92cded8ef2a2099d88b597b26fa5f 324 Gene3D G3DSA:3.40.1190.20 1 322 2.7E-43 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS15345 4df92cded8ef2a2099d88b597b26fa5f 324 SUPERFAMILY SSF53613 2 296 7.02E-54 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 161 286 4.6E-8 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 SUPERFAMILY SSF58104 181 292 9.42E-5 T 29-03-2018 MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 Pfam PF02470 MlaD protein 37 110 1.6E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 Gene3D G3DSA:1.10.287.1060 188 300 7.6E-4 T 29-03-2018 MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 300 8.3E-84 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22265 18c87b3fc05dfc632c938c1b3f95d939 472 Gene3D G3DSA:1.10.287.1060 134 187 0.0097 T 29-03-2018 MSG_RS15190 9c959b136fd616becf009d15f4a6ba7c 349 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS15190 9c959b136fd616becf009d15f4a6ba7c 349 Gene3D G3DSA:1.10.600.10 1 349 1.2E-85 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS15190 9c959b136fd616becf009d15f4a6ba7c 349 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 225 237 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS15190 9c959b136fd616becf009d15f4a6ba7c 349 SUPERFAMILY SSF48576 9 348 7.2E-76 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS15190 9c959b136fd616becf009d15f4a6ba7c 349 Pfam PF00348 Polyprenyl synthetase 32 293 9.2E-49 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MSG_RS17100 af15f96a62bf47429f1e0daa4447c2f5 120 Pfam PF00188 Cysteine-rich secretory protein family 18 109 1.2E-11 T 29-03-2018 IPR014044 CAP domain MSG_RS17100 af15f96a62bf47429f1e0daa4447c2f5 120 SUPERFAMILY SSF55797 18 108 1.78E-12 T 29-03-2018 IPR014044 CAP domain MSG_RS17100 af15f96a62bf47429f1e0daa4447c2f5 120 Gene3D G3DSA:3.40.33.10 11 118 3.8E-7 T 29-03-2018 IPR014044 CAP domain MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 Gene3D G3DSA:3.40.50.300 248 488 1.4E-8 T 29-03-2018 MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 SUPERFAMILY SSF55073 57 236 2.35E-37 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 Pfam PF13191 AAA ATPase domain 247 436 3.5E-13 T 29-03-2018 MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 Gene3D G3DSA:1.25.40.10 706 1059 3.4E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 SMART SM00044 23 223 5.2E-5 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 59 225 1.6E-19 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 SUPERFAMILY SSF52540 240 322 7.14E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 SUPERFAMILY SSF52540 384 501 7.14E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02765 9cc5224bfbafa6aad083ab35655f137d 1060 Gene3D G3DSA:3.30.70.1230 55 241 3.5E-30 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS12440 5fc9df723e02214ce1e3d8bc6f561209 242 Pfam PF01925 Sulfite exporter TauE/SafE 7 234 5.9E-22 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MSG_RS03075 aa62ca21f9acb90dbcc3e7310e0c92c9 290 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 13 232 2.5E-89 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c MSG_RS03075 aa62ca21f9acb90dbcc3e7310e0c92c9 290 SUPERFAMILY SSF51679 8 288 7.8E-58 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS03075 aa62ca21f9acb90dbcc3e7310e0c92c9 290 Gene3D G3DSA:3.20.20.30 1 250 3.8E-56 T 29-03-2018 MSG_RS03075 aa62ca21f9acb90dbcc3e7310e0c92c9 290 Pfam PF00296 Luciferase-like monooxygenase 21 253 3.5E-41 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS03075 aa62ca21f9acb90dbcc3e7310e0c92c9 290 Gene3D G3DSA:3.20.20.30 251 289 0.015 T 29-03-2018 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 PRINTS PR00762 Chloride channel signature 117 134 1.7E-15 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 PRINTS PR00762 Chloride channel signature 367 387 1.7E-15 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 PRINTS PR00762 Chloride channel signature 421 440 1.7E-15 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 PRINTS PR00762 Chloride channel signature 197 216 1.7E-15 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 PRINTS PR00762 Chloride channel signature 403 419 1.7E-15 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 Pfam PF00654 Voltage gated chloride channel 104 451 8.5E-82 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 SUPERFAMILY SSF81340 29 467 6.15E-90 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MSG_RS01490 971b25ddd5b086480bc3f2f2c3ecae3d 481 Gene3D G3DSA:1.10.3080.10 26 476 6.2E-79 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MSG_RS11405 62db496369650fa8d0b7e9515d65e9bf 225 Pfam PF00753 Metallo-beta-lactamase superfamily 33 204 3.3E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS11405 62db496369650fa8d0b7e9515d65e9bf 225 Gene3D G3DSA:3.60.15.10 23 223 4.3E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS11405 62db496369650fa8d0b7e9515d65e9bf 225 SUPERFAMILY SSF56281 31 221 2.03E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS11405 62db496369650fa8d0b7e9515d65e9bf 225 SMART SM00849 36 204 8.6E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 Gene3D G3DSA:1.10.10.10 850 913 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 Gene3D G3DSA:1.25.40.10 315 618 0.012 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 Gene3D G3DSA:1.25.40.10 619 836 0.0016 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 857 871 8.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 899 8.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 871 887 8.2E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 ProSitePatterns PS00622 LuxR-type HTH domain signature. 871 898 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 Pfam PF00196 Bacterial regulatory proteins, luxR family 857 909 2.7E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 SUPERFAMILY SSF46894 850 911 6.12E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 SMART SM00421 854 911 3.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 SUPERFAMILY SSF52540 43 252 4.66E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22700 690478ecc2fc75d70e3ff1054cb30598 915 Gene3D G3DSA:3.40.50.300 40 189 3.2E-8 T 29-03-2018 MSG_RS18375 790e96ca381378b35b0c604ab045169e 52 SUPERFAMILY SSF51735 5 45 8.24E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18375 790e96ca381378b35b0c604ab045169e 52 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 43 1.7E-7 T 29-03-2018 MSG_RS18375 790e96ca381378b35b0c604ab045169e 52 Gene3D G3DSA:3.40.50.720 1 51 5.4E-10 T 29-03-2018 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 SUPERFAMILY SSF54862 3 70 9.18E-17 T 29-03-2018 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 Gene3D G3DSA:3.30.70.20 45 105 1.5E-6 T 29-03-2018 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 Gene3D G3DSA:3.30.70.20 2 44 4.0E-8 T 29-03-2018 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 MSG_RS13870 a470f96bc46bc262e2622bd39f3e1c56 118 Pfam PF00037 4Fe-4S binding domain 34 56 1.4E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS00970 3bdbd384609cce3b5211dba2647e027d 183 SUPERFAMILY SSF69118 1 181 2.21E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS00970 3bdbd384609cce3b5211dba2647e027d 183 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 134 1.9E-5 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS00970 3bdbd384609cce3b5211dba2647e027d 183 Gene3D G3DSA:1.20.1290.10 31 183 1.1E-23 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS11095 8a83acd6515713960390400eb549761f 610 Gene3D G3DSA:1.20.1050.50 20 210 3.2E-57 T 29-03-2018 MSG_RS12645 031c4eeae329c64d9f1e896760bab362 64 Gene3D G3DSA:3.30.70.20 1 64 1.5E-5 T 29-03-2018 MSG_RS12645 031c4eeae329c64d9f1e896760bab362 64 Pfam PF13459 4Fe-4S single cluster domain 3 61 2.1E-13 T 29-03-2018 MSG_RS12645 031c4eeae329c64d9f1e896760bab362 64 SUPERFAMILY SSF54862 3 62 2.68E-8 T 29-03-2018 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Gene3D G3DSA:2.30.38.10 334 416 3.4E-26 T 29-03-2018 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 514 5.5E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Gene3D G3DSA:3.40.50.980 183 333 2.7E-38 T 29-03-2018 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Pfam PF00501 AMP-binding enzyme 21 423 6.4E-81 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Gene3D G3DSA:3.40.50.980 14 182 2.2E-21 T 29-03-2018 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 SUPERFAMILY SSF56801 18 527 1.13E-127 T 29-03-2018 MSG_RS03825 7bc030366ab5e559af7f14e871df68f0 533 Gene3D G3DSA:3.30.300.30 418 532 4.3E-28 T 29-03-2018 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 Gene3D G3DSA:1.20.1560.10 45 409 1.1E-27 T 29-03-2018 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 SUPERFAMILY SSF90123 65 391 9.29E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 SUPERFAMILY SSF90123 555 564 9.29E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 Gene3D G3DSA:3.40.50.300 410 630 1.9E-32 T 29-03-2018 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 Pfam PF00005 ABC transporter 444 579 1.8E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 ProSitePatterns PS00211 ABC transporters family signature. 551 565 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 SMART SM00382 452 633 2.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 SUPERFAMILY SSF52540 419 627 1.45E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12785 69f920b2847f8eaa3a5fdb7802e5e071 639 Pfam PF06472 ABC transporter transmembrane region 2 45 358 2.3E-91 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 SUPERFAMILY SSF55811 82 193 5.55E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 Pfam PF00293 NUDIX domain 83 185 6.9E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 Gene3D G3DSA:3.90.79.10 58 200 1.0E-28 T 29-03-2018 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 ProSitePatterns PS00893 Nudix box signature. 99 120 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 PRINTS PR00502 NUDIX hydrolase family signature 94 108 1.4E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS24635 7c8768fb0182f2a08275627601e85e8e 244 PRINTS PR00502 NUDIX hydrolase family signature 108 123 1.4E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS11185 3274ac3ed076c3fa24c6f5bde832a7da 261 Gene3D G3DSA:3.20.20.70 9 257 1.2E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11185 3274ac3ed076c3fa24c6f5bde832a7da 261 SUPERFAMILY SSF51366 8 261 7.85E-80 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS11185 3274ac3ed076c3fa24c6f5bde832a7da 261 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 7 261 3.3E-113 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MSG_RS11185 3274ac3ed076c3fa24c6f5bde832a7da 261 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 6 261 47.881 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MSG_RS11185 3274ac3ed076c3fa24c6f5bde832a7da 261 Pfam PF00977 Histidine biosynthesis protein 10 245 3.4E-87 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 SUPERFAMILY SSF54565 2 95 6.15E-32 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 Pfam PF00886 Ribosomal protein S16 9 67 3.6E-22 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.3E-30 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 Gene3D G3DSA:3.30.1320.10 2 84 4.7E-29 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08195 8455c916bb635793fb52a61105cb1a76 167 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.185 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 SUPERFAMILY SSF52743 274 402 4.45E-52 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 SUPERFAMILY SSF52743 74 244 4.45E-52 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 Gene3D G3DSA:3.40.50.200 65 409 7.6E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 Pfam PF00082 Subtilase family 89 393 4.7E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 343 359 2.7E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 125 138 2.7E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 108 2.7E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS11615 76f35cdfa09b006321792dbc043df464 463 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 79 458 7.8E-113 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Gene3D G3DSA:3.40.50.1220 199 352 1.2E-17 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Gene3D G3DSA:3.40.50.970 355 556 3.6E-39 T 29-03-2018 MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 SUPERFAMILY SSF52518 13 192 2.06E-40 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 540 1.8E-18 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 SUPERFAMILY SSF52518 370 554 1.73E-45 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Gene3D G3DSA:3.40.50.970 7 198 5.8E-45 T 29-03-2018 MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 SUPERFAMILY SSF52467 177 347 2.81E-24 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 326 2.0E-11 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 PIRSF PIRSF036565 9 564 4.3E-200 T 29-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 MSG_RS20985 bd07be5301169ca41d2f110f3258deb8 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 187 3.9E-32 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 282 298 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 33 485 43.917 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 SUPERFAMILY SSF53383 24 138 8.06E-141 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 SUPERFAMILY SSF53383 170 485 8.06E-141 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 PIRSF PIRSF000412 11 481 5.5E-158 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 Gene3D G3DSA:3.40.640.10 63 333 1.1E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 Pfam PF00464 Serine hydroxymethyltransferase 35 149 1.1E-27 T 29-03-2018 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 Pfam PF00464 Serine hydroxymethyltransferase 170 443 2.2E-94 T 29-03-2018 MSG_RS19575 97f1cb5bce3f65f3fb768f07085b0e31 489 Gene3D G3DSA:3.90.1150.10 334 478 4.9E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS10320 b10a4a74aab953c38c4e882c83e06f00 274 SUPERFAMILY SSF53335 26 181 1.8E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10320 b10a4a74aab953c38c4e882c83e06f00 274 Pfam PF08241 Methyltransferase domain 54 147 5.5E-20 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS10320 b10a4a74aab953c38c4e882c83e06f00 274 Gene3D G3DSA:3.40.50.150 38 274 1.4E-28 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 PIRSF PIRSF000850 152 220 2.8 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 PIRSF PIRSF000850 83 152 0.69 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 PIRSF PIRSF000850 232 306 0.051 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 Gene3D G3DSA:3.30.870.10 3 157 1.6E-25 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 Pfam PF13091 PLD-like domain 172 299 1.4E-23 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 Pfam PF13091 PLD-like domain 21 146 6.7E-20 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 SUPERFAMILY SSF56024 159 315 2.47E-28 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 SUPERFAMILY SSF56024 7 148 5.61E-26 T 29-03-2018 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 SMART SM00155 91 118 3.5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 SMART SM00155 244 271 3.5E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MSG_RS05255 c3fc95a4d7ec6b16faffcba53c854269 330 Gene3D G3DSA:3.30.870.10 162 323 1.1E-27 T 29-03-2018 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 Gene3D G3DSA:3.40.50.1450 3 166 4.0E-47 T 29-03-2018 IPR023430 Peptidase HybD-like domain MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 151 4.7E-35 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 PRINTS PR00446 Hydrogen uptake protein signature 5 17 1.1E-13 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 PRINTS PR00446 Hydrogen uptake protein signature 58 68 1.1E-13 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 PRINTS PR00446 Hydrogen uptake protein signature 69 85 1.1E-13 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 PRINTS PR00446 Hydrogen uptake protein signature 36 53 1.1E-13 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 PRINTS PR00446 Hydrogen uptake protein signature 17 28 1.1E-13 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 Pfam PF01750 Hydrogenase maturation protease 35 151 5.6E-15 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14040 da482baea378fca12a634d6db9b47c80 167 SUPERFAMILY SSF53163 4 158 8.63E-35 T 29-03-2018 IPR023430 Peptidase HybD-like domain MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 Gene3D G3DSA:1.10.8.300 213 321 1.9E-33 T 29-03-2018 MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 PIRSF PIRSF002849 2 325 8.6E-132 T 29-03-2018 MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 SMART SM00382 46 187 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 9.6E-64 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 SUPERFAMILY SSF52540 13 297 3.02E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23295 504130b4fa502ebd1a861140613131a3 325 Gene3D G3DSA:3.40.50.300 30 196 5.1E-28 T 29-03-2018 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 Gene3D G3DSA:1.10.357.10 59 194 3.1E-25 T 29-03-2018 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 6.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 SUPERFAMILY SSF46689 3 76 2.1E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 Gene3D G3DSA:1.10.10.60 1 58 6.1E-19 T 29-03-2018 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 SUPERFAMILY SSF48498 82 190 1.42E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 83 188 1.2E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23940 ab0896ab1c6be414bc7e9512dc0e028a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.3E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Pfam PF01565 FAD binding domain 34 167 1.5E-22 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 360 3.4E-45 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 SUPERFAMILY SSF56176 20 200 2.0E-35 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 231 361 5.9E-35 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Gene3D G3DSA:3.30.465.10 91 243 1.2E-48 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Gene3D G3DSA:3.90.78.10 248 362 8.0E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Gene3D G3DSA:3.30.43.10 10 88 9.4E-17 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 366 73.461 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS03435 0cccc4faaf13cc50df582c2c1d4ce0c5 366 SUPERFAMILY SSF56194 230 364 5.49E-33 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS17240 6248d3894445f6264a1f2d808a77611d 396 SUPERFAMILY SSF56601 16 387 8.79E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS17240 6248d3894445f6264a1f2d808a77611d 396 Pfam PF00144 Beta-lactamase 26 382 3.0E-64 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS17240 6248d3894445f6264a1f2d808a77611d 396 Gene3D G3DSA:3.40.710.10 4 395 5.1E-77 T 29-03-2018 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Pfam PF00501 AMP-binding enzyme 10 450 2.2E-46 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Gene3D G3DSA:3.40.50.980 2 192 1.2E-27 T 29-03-2018 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 SUPERFAMILY SSF56801 4 550 4.06E-89 T 29-03-2018 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Gene3D G3DSA:2.30.38.10 357 445 5.8E-6 T 29-03-2018 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Gene3D G3DSA:3.30.300.30 446 553 3.3E-23 T 29-03-2018 MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 539 2.4E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS09510 0b520903e9a5b47e90a753c503641538 553 Gene3D G3DSA:3.40.50.980 193 356 2.2E-23 T 29-03-2018 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 Gene3D G3DSA:3.40.47.10 162 393 1.0E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 SUPERFAMILY SSF53901 270 385 5.76E-14 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 Gene3D G3DSA:3.40.1160.10 7 114 0.0019 T 29-03-2018 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 PIRSF PIRSF000429 250 353 3.3E-4 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 PIRSF PIRSF000429 2 90 0.043 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 PIRSF PIRSF000429 136 218 120.0 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 SUPERFAMILY SSF53901 197 396 4.55E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07270 edb7c8b930f36a2b8d41d3de202edccb 397 SUPERFAMILY SSF53901 19 108 4.55E-11 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 8 237 32.619 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 SUPERFAMILY SSF53335 7 231 5.58E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 145 159 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 236 2.9E-60 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 17 236 1.1E-62 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS05355 5e9f4cde1656e9911cd8f9f4fdd1df48 241 Gene3D G3DSA:3.40.50.150 4 236 1.2E-40 T 29-03-2018 MSG_RS16475 5b486219a6cd73c550a37bc68f689e2e 467 Gene3D G3DSA:1.20.1250.20 24 221 1.6E-11 T 29-03-2018 MSG_RS16475 5b486219a6cd73c550a37bc68f689e2e 467 SUPERFAMILY SSF103473 28 453 3.14E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS16475 5b486219a6cd73c550a37bc68f689e2e 467 Pfam PF07690 Major Facilitator Superfamily 41 380 4.1E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS16475 5b486219a6cd73c550a37bc68f689e2e 467 Gene3D G3DSA:1.20.1250.20 225 457 2.1E-13 T 29-03-2018 MSG_RS00485 bfd4589a64f49bba167cdcd412b8d192 194 SUPERFAMILY SSF46689 19 82 6.98E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00485 bfd4589a64f49bba167cdcd412b8d192 194 Gene3D G3DSA:1.10.10.60 2 58 2.5E-13 T 29-03-2018 MSG_RS00485 bfd4589a64f49bba167cdcd412b8d192 194 Gene3D G3DSA:1.10.10.60 59 185 5.6E-11 T 29-03-2018 MSG_RS00485 bfd4589a64f49bba167cdcd412b8d192 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 6.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11265 c482b4a11b983aa80e30b4a826a36d06 305 SUPERFAMILY SSF51679 12 291 1.06E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS11265 c482b4a11b983aa80e30b4a826a36d06 305 Pfam PF00296 Luciferase-like monooxygenase 16 280 4.1E-45 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS11265 c482b4a11b983aa80e30b4a826a36d06 305 Gene3D G3DSA:3.20.20.30 5 305 6.7E-54 T 29-03-2018 MSG_RS11265 c482b4a11b983aa80e30b4a826a36d06 305 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 21 284 3.5E-113 T 29-03-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted MSG_RS06095 de11f6f84de4b26587aa1ab6168be320 213 Gene3D G3DSA:3.90.1150.10 95 213 2.6E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS06095 de11f6f84de4b26587aa1ab6168be320 213 Pfam PF02347 Glycine cleavage system P-protein 2 208 7.5E-24 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS06095 de11f6f84de4b26587aa1ab6168be320 213 SUPERFAMILY SSF53383 2 211 2.09E-21 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 548 856 4.8E-112 T 29-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Gene3D G3DSA:3.20.20.70 26 378 2.0E-31 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Hamap MF_01611 FO synthase subunit 1 [cofG]. 85 417 51.233 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 514 857 3.4E-160 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Pfam PF04055 Radical SAM superfamily 556 727 1.7E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Pfam PF04055 Radical SAM superfamily 93 276 1.2E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 SUPERFAMILY SSF102114 512 823 4.19E-45 T 29-03-2018 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 SMART SM00729 89 326 1.2E-4 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 86 415 3.4E-145 T 29-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Hamap MF_01612 FO synthase subunit 2 [cofH]. 500 859 50.74 T 29-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 SUPERFAMILY SSF102114 40 392 5.49E-38 T 29-03-2018 MSG_RS19090 a9060a8baee9943939dea3331d83851c 860 Gene3D G3DSA:3.20.20.70 491 860 2.2E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS18650 1df7d4eb202ccdeda16ef710dc6d76a3 123 SUPERFAMILY SSF46785 16 119 2.07E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18650 1df7d4eb202ccdeda16ef710dc6d76a3 123 Pfam PF01638 HxlR-like helix-turn-helix 27 118 2.6E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS18650 1df7d4eb202ccdeda16ef710dc6d76a3 123 Gene3D G3DSA:1.10.10.10 9 123 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 Pfam PF03099 Biotin/lipoate A/B protein ligase family 56 161 1.6E-5 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 Gene3D G3DSA:2.30.30.100 224 272 1.4E-17 T 29-03-2018 MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 SUPERFAMILY SSF55681 21 204 7.12E-38 T 29-03-2018 MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 Pfam PF02237 Biotin protein ligase C terminal domain 224 270 1.9E-10 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 32 270 6.0E-34 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MSG_RS05710 80375a9b5b87843fba70e32d4af47672 273 Gene3D G3DSA:3.30.930.10 1 223 6.2E-55 T 29-03-2018 MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Pfam PF12804 MobA-like NTP transferase domain 9 187 9.4E-20 T 29-03-2018 IPR025877 MobA-like NTP transferase MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 469 1.9E-170 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 SUPERFAMILY SSF51161 265 458 5.85E-41 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 SUPERFAMILY SSF53448 8 268 2.5E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Gene3D G3DSA:3.90.550.10 1 255 5.1E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 334 366 5.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 282 315 2.6E-5 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 410 443 4.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Gene3D G3DSA:2.160.10.10 364 495 3.2E-20 T 29-03-2018 MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 467 38.664 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MSG_RS19880 e69f3dc29f8ea0b1a73e138328e5532f 495 Gene3D G3DSA:2.160.10.10 256 363 6.5E-22 T 29-03-2018 MSG_RS21305 cde0d0501659214df85779ff9c9baee7 169 Pfam PF02627 Carboxymuconolactone decarboxylase family 38 119 6.7E-14 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS21305 cde0d0501659214df85779ff9c9baee7 169 SUPERFAMILY SSF69118 1 168 1.96E-34 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS21305 cde0d0501659214df85779ff9c9baee7 169 Gene3D G3DSA:1.20.1290.10 27 169 2.0E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 Pfam PF00561 alpha/beta hydrolase fold 37 140 2.8E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 3.1E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 3.1E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 234 248 3.1E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 3.1E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00412 Epoxide hydrolase signature 265 287 2.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00412 Epoxide hydrolase signature 62 77 2.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00412 Epoxide hydrolase signature 121 134 2.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 PRINTS PR00412 Epoxide hydrolase signature 42 60 2.4E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 SUPERFAMILY SSF53474 15 286 1.41E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20645 c5990bca64bc354e5f35a568d61795da 289 Gene3D G3DSA:3.40.50.1820 11 289 3.1E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 163 1.7E-21 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 Gene3D G3DSA:3.40.50.720 1 290 2.1E-39 T 29-03-2018 MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 SUPERFAMILY SSF52009 758 859 4.32E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 Pfam PF00391 PEP-utilising enzyme, mobile domain 787 856 4.9E-20 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 Gene3D G3DSA:3.50.30.10 759 864 4.8E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS14530 78ae5de1c761cc1937cf51e4b12764a2 865 SUPERFAMILY SSF51735 2 277 1.17E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23695 6d75f5b711258026c89ef732994be418 198 SUPERFAMILY SSF46689 9 80 1.85E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 Gene3D G3DSA:1.10.10.60 5 65 5.7E-22 T 29-03-2018 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 Gene3D G3DSA:1.10.357.10 66 195 4.3E-18 T 29-03-2018 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.3E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23695 6d75f5b711258026c89ef732994be418 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS17185 8387f96fa6ea024959fddf5b4e43f595 181 Pfam PF06737 Transglycosylase-like domain 106 177 1.3E-32 T 29-03-2018 IPR010618 Transglycosylase-like MSG_RS17185 8387f96fa6ea024959fddf5b4e43f595 181 Gene3D G3DSA:1.10.530.10 53 181 1.3E-28 T 29-03-2018 MSG_RS17185 8387f96fa6ea024959fddf5b4e43f595 181 SUPERFAMILY SSF53955 104 180 2.6E-30 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 Gene3D G3DSA:3.40.50.720 12 255 1.2E-58 T 29-03-2018 MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.2E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 187 1.9E-4 T 29-03-2018 MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 6.7E-47 T 29-03-2018 MSG_RS11785 d461435ae3b263089ef7f902a4142cac 255 SUPERFAMILY SSF51735 10 254 4.72E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 SUPERFAMILY SSF50494 195 379 6.01E-37 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 Gene3D G3DSA:2.40.10.10 289 397 4.5E-17 T 29-03-2018 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 Gene3D G3DSA:2.40.10.10 191 288 1.3E-19 T 29-03-2018 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 Pfam PF02674 Colicin V production protein 7 148 9.1E-13 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 Pfam PF13365 Trypsin-like peptidase domain 220 357 1.1E-23 T 29-03-2018 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 PRINTS PR00834 HtrA/DegQ protease family signature 287 311 4.5E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 PRINTS PR00834 HtrA/DegQ protease family signature 328 345 4.5E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 4.5E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS23110 c080c7e323fe48882e3a3ad6ac285dab 397 PRINTS PR00834 HtrA/DegQ protease family signature 248 268 4.5E-12 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS07370 634e1ed18f85c636c0f3e223119d9bf7 521 Gene3D G3DSA:3.50.50.60 176 507 1.5E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07370 634e1ed18f85c636c0f3e223119d9bf7 521 Gene3D G3DSA:3.50.50.60 19 175 5.0E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07370 634e1ed18f85c636c0f3e223119d9bf7 521 SUPERFAMILY SSF51905 307 428 3.63E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07370 634e1ed18f85c636c0f3e223119d9bf7 521 SUPERFAMILY SSF51905 21 237 3.63E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07370 634e1ed18f85c636c0f3e223119d9bf7 521 Pfam PF00743 Flavin-binding monooxygenase-like 21 224 3.2E-17 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 Gene3D G3DSA:3.40.190.10 51 218 2.3E-32 T 29-03-2018 MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 Gene3D G3DSA:3.40.190.10 219 371 3.6E-15 T 29-03-2018 MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 SUPERFAMILY SSF53850 51 370 1.25E-82 T 29-03-2018 MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 52 370 3.2E-101 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 Pfam PF12849 PBP superfamily domain 47 337 4.3E-54 T 29-03-2018 IPR024370 PBP domain MSG_RS13260 130fee8580916fb547ee60f089b8b914 371 PIRSF PIRSF002756 6 371 2.7E-108 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Pfam PF01061 ABC-2 type transporter 640 859 4.4E-13 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Gene3D G3DSA:2.60.200.20 8 118 1.2E-19 T 29-03-2018 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SUPERFAMILY SSF49879 270 349 4.4E-19 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SMART SM00240 25 75 9.9E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SMART SM00240 274 323 3.8E-11 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SMART SM00382 386 570 3.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Pfam PF00498 FHA domain 276 337 1.5E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Pfam PF00498 FHA domain 26 89 2.0E-14 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Gene3D G3DSA:2.60.200.20 127 357 5.1E-17 T 29-03-2018 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Gene3D G3DSA:3.40.50.300 359 649 1.2E-64 T 29-03-2018 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 Pfam PF00005 ABC transporter 377 524 4.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SUPERFAMILY SSF49879 8 103 9.37E-22 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS11365 9c1cf534d817c338bb3522df09c6c6c0 912 SUPERFAMILY SSF52540 358 591 6.35E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS21705 c396ec4217b3e8c51fa756cc7de59269 270 Pfam PF11209 Protein of unknown function (DUF2993) 28 255 3.8E-25 T 29-03-2018 IPR021373 Protein of unknown function DUF2993 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 SUPERFAMILY SSF48498 84 211 3.4E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 Gene3D G3DSA:1.10.357.10 67 202 8.8E-13 T 29-03-2018 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 SUPERFAMILY SSF46689 4 86 3.33E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19970 ce8a146d9c017634be55212093a7ee75 225 Gene3D G3DSA:1.10.10.60 2 66 3.7E-15 T 29-03-2018 MSG_RS09825 060259e9474e9ee71183906f728b75f8 354 Pfam PF10005 zinc-ribbon domain 4 95 4.7E-24 T 29-03-2018 IPR011201 Zinc-ribbon domain, bacteria MSG_RS09825 060259e9474e9ee71183906f728b75f8 354 PIRSF PIRSF012641 1 354 4.5E-143 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase MSG_RS09825 060259e9474e9ee71183906f728b75f8 354 Pfam PF15887 Putative zinc-binding metallo-peptidase 102 337 3.3E-99 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase MSG_RS09825 060259e9474e9ee71183906f728b75f8 354 Gene3D G3DSA:3.40.390.10 98 277 7.5E-16 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 340 428 6.0E-14 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 75 331 6.7E-58 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 471 3.2E-148 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 Gene3D G3DSA:2.40.37.10 322 472 6.4E-39 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 322 341 1.6E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 229 242 1.6E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 428 441 1.6E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 1.6E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 1.6E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 SUPERFAMILY SSF50621 312 471 2.51E-51 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 SUPERFAMILY SSF51419 64 333 9.01E-70 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 53 471 39.102 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 268 285 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 Gene3D G3DSA:3.20.20.10 72 321 6.0E-63 T 29-03-2018 IPR029066 PLP-binding barrel MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 355 373 2.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 438 460 2.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 2.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS18335 836eb97ecb24116ca9a81380c785bceb 472 PRINTS PR01181 Diaminopimelate decarboxylase signature 201 210 2.1E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS10540 e7806990ba56318f1105ae40e52788ae 200 SUPERFAMILY SSF46689 9 73 7.18E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10540 e7806990ba56318f1105ae40e52788ae 200 SUPERFAMILY SSF48498 83 197 2.67E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS10540 e7806990ba56318f1105ae40e52788ae 200 Gene3D G3DSA:1.10.10.60 1 56 1.2E-7 T 29-03-2018 MSG_RS10540 e7806990ba56318f1105ae40e52788ae 200 Gene3D G3DSA:1.10.357.10 57 198 1.5E-17 T 29-03-2018 MSG_RS14125 924dd5816f7f25a550dfc01646e0e718 267 SUPERFAMILY SSF69754 25 101 4.58E-9 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS14125 924dd5816f7f25a550dfc01646e0e718 267 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 25 104 5.0E-6 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS14125 924dd5816f7f25a550dfc01646e0e718 267 Gene3D G3DSA:3.30.160.100 11 112 1.6E-8 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS14125 924dd5816f7f25a550dfc01646e0e718 267 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 140 194 2.2E-14 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal MSG_RS14125 924dd5816f7f25a550dfc01646e0e718 267 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 217 262 5.5E-11 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal MSG_RS15270 ba299426c3a45f177bbcc46a4b1206ae 282 Pfam PF13699 Domain of unknown function (DUF4157) 119 165 3.7E-5 T 29-03-2018 IPR025295 Domain of unknown function DUF4157 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 SUPERFAMILY SSF56784 306 326 9.7E-45 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 SUPERFAMILY SSF56784 365 605 9.7E-45 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Gene3D G3DSA:1.20.120.520 619 786 4.9E-15 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Gene3D G3DSA:3.40.50.1000 430 577 5.6E-31 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 66 606 8.0E-150 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Gene3D G3DSA:3.40.1110.10 326 429 1.0E-17 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 504 523 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 429 440 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 308 322 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 540 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 462 1.8E-23 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 327 7.8E-27 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 418 582 8.8E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Pfam PF01814 Hemerythrin HHE cation binding domain 625 761 2.3E-15 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 517 4.1E-33 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 66 609 1.5E-139 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 SUPERFAMILY SSF81653 119 215 9.29E-19 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Gene3D G3DSA:1.20.1110.10 66 325 9.2E-25 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 310 316 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 Pfam PF00122 E1-E2 ATPase 121 288 4.0E-35 T 29-03-2018 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 SUPERFAMILY SSF81665 217 302 2.22E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05600 daecee0e5a5967a971e39410e9bbd568 816 SUPERFAMILY SSF81665 73 120 2.22E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 SUPERFAMILY SSF51735 3 235 1.47E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 Gene3D G3DSA:3.40.50.720 1 238 1.2E-49 T 29-03-2018 MSG_RS21845 421092a0e36ea97426d0364f7a49f330 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 234 6.9E-38 T 29-03-2018 MSG_RS08950 f50e1b8e6548ee5fdbc8155f366655fe 166 SMART SM00257 115 164 0.0025 T 29-03-2018 IPR018392 LysM domain MSG_RS08950 f50e1b8e6548ee5fdbc8155f366655fe 166 Pfam PF01476 LysM domain 117 164 3.2E-7 T 29-03-2018 IPR018392 LysM domain MSG_RS08950 f50e1b8e6548ee5fdbc8155f366655fe 166 Gene3D G3DSA:3.10.350.10 114 165 7.7E-6 T 29-03-2018 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 Gene3D G3DSA:2.60.120.10 303 408 4.5E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 Pfam PF01238 Phosphomannose isomerase type I 5 368 8.1E-62 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 SUPERFAMILY SSF51182 3 389 1.67E-94 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 7 393 4.3E-70 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 Gene3D G3DSA:1.10.441.10 163 271 9.8E-27 T 29-03-2018 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PIRSF PIRSF001480 1 408 5.2E-103 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 Gene3D G3DSA:2.60.120.10 5 162 7.4E-41 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS05860 75b9ebfbadc5da9caff4d06fd2531dbc 408 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 2.9E-63 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MSG_RS02870 1771ce9141cbe95d8d2c52d85f43253c 217 SUPERFAMILY SSF54637 15 210 1.61E-41 T 29-03-2018 IPR029069 HotDog domain MSG_RS02870 1771ce9141cbe95d8d2c52d85f43253c 217 Pfam PF03061 Thioesterase superfamily 127 195 6.5E-8 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS02870 1771ce9141cbe95d8d2c52d85f43253c 217 Gene3D G3DSA:3.10.129.10 75 210 3.2E-20 T 29-03-2018 MSG_RS07955 5ad9b45668add4bc7da30f862a858a5d 255 Gene3D G3DSA:3.40.30.10 69 244 1.2E-29 T 29-03-2018 MSG_RS07955 5ad9b45668add4bc7da30f862a858a5d 255 Pfam PF13462 Thioredoxin 73 237 1.9E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS07955 5ad9b45668add4bc7da30f862a858a5d 255 SUPERFAMILY SSF52833 72 236 1.33E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS03580 ede7901050a994467ca24cfdc4486e26 103 Gene3D G3DSA:1.10.287.1060 3 100 4.4E-20 T 29-03-2018 MSG_RS03580 ede7901050a994467ca24cfdc4486e26 103 SUPERFAMILY SSF140453 7 99 6.67E-19 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS03580 ede7901050a994467ca24cfdc4486e26 103 Pfam PF06013 Proteins of 100 residues with WXG 7 90 2.8E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS03580 ede7901050a994467ca24cfdc4486e26 103 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 95 2.3E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS04020 37c9d508480267f66ad837a5ed46605b 171 Gene3D G3DSA:3.40.109.10 1 171 3.9E-45 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS04020 37c9d508480267f66ad837a5ed46605b 171 Pfam PF00881 Nitroreductase family 68 145 2.5E-9 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS04020 37c9d508480267f66ad837a5ed46605b 171 Pfam PF00881 Nitroreductase family 9 60 3.2E-16 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS04020 37c9d508480267f66ad837a5ed46605b 171 SUPERFAMILY SSF55469 1 171 2.62E-49 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 SUPERFAMILY SSF47203 225 367 3.05E-11 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 PIRSF PIRSF016578 2 383 2.5E-18 T 29-03-2018 MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 Gene3D G3DSA:2.40.110.10 110 200 7.7E-17 T 29-03-2018 MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 230 365 1.8E-9 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 SUPERFAMILY SSF56645 7 209 6.28E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS09905 5852fc99dd701ba0a955a2d0fb318787 390 Gene3D G3DSA:1.20.140.10 201 368 2.6E-14 T 29-03-2018 MSG_RS20635 c6e629d9f5df600558c5c3cd12205ef0 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 242 3.2E-42 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS20635 c6e629d9f5df600558c5c3cd12205ef0 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 90 110 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS20635 c6e629d9f5df600558c5c3cd12205ef0 243 SUPERFAMILY SSF52096 6 242 2.26E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20635 c6e629d9f5df600558c5c3cd12205ef0 243 Gene3D G3DSA:3.90.226.10 2 188 3.8E-49 T 29-03-2018 MSG_RS20635 c6e629d9f5df600558c5c3cd12205ef0 243 Gene3D G3DSA:1.10.12.10 189 243 1.1E-11 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS11140 b2f5aa72eade383943e023bced296849 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 285 7.9E-96 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 PIRSF PIRSF006250 5 285 4.9E-106 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 SUPERFAMILY SSF51690 117 285 8.24E-55 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 Gene3D G3DSA:3.20.20.70 143 275 6.9E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 Gene3D G3DSA:3.90.1170.20 3 142 9.0E-40 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 SUPERFAMILY SSF54675 9 116 6.18E-28 T 29-03-2018 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 115 1.9E-20 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MSG_RS11140 b2f5aa72eade383943e023bced296849 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 284 4.9E-61 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 Gene3D G3DSA:3.40.390.30 2 166 1.3E-41 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 160 20.765 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 8.9E-32 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 SUPERFAMILY SSF55486 5 147 4.15E-38 T 29-03-2018 MSG_RS16710 680ad42859796a0cd305288f707ad12a 177 Pfam PF02130 Uncharacterized protein family UPF0054 19 147 2.2E-35 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Gene3D G3DSA:3.90.650.10 201 401 5.8E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 SUPERFAMILY SSF55326 51 214 4.34E-49 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 PIRSF PIRSF001587 13 772 3.4E-277 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 772 306.151 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Pfam PF02769 AIR synthase related protein, C-terminal domain 606 742 2.0E-21 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Pfam PF02769 AIR synthase related protein, C-terminal domain 223 386 2.0E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Gene3D G3DSA:3.90.650.10 601 772 2.3E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 SUPERFAMILY SSF56042 606 771 2.39E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Pfam PF00586 AIR synthase related protein, N-terminal domain 488 591 5.2E-23 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Pfam PF00586 AIR synthase related protein, N-terminal domain 108 209 1.0E-23 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 34 765 1.3E-248 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 SUPERFAMILY SSF56042 222 459 6.43E-52 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Gene3D G3DSA:3.30.1330.10 430 597 2.5E-44 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 Gene3D G3DSA:3.30.1330.10 33 200 5.1E-55 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21800 b97b1327bf81986b4294666066b7b831 772 SUPERFAMILY SSF55326 428 598 9.55E-56 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS24220 781b7049ccb7f78d4da8859983755212 545 SMART SM00701 201 349 2.8E-67 T 29-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS24220 781b7049ccb7f78d4da8859983755212 545 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 226 378 5.1E-15 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS24220 781b7049ccb7f78d4da8859983755212 545 SUPERFAMILY SSF55846 200 396 2.22E-50 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS24220 781b7049ccb7f78d4da8859983755212 545 Pfam PF08310 LGFP repeat 425 476 1.1E-16 T 29-03-2018 IPR013207 LGFP MSG_RS24220 781b7049ccb7f78d4da8859983755212 545 Gene3D G3DSA:3.40.80.10 196 400 1.6E-45 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 161 1.8E-42 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 SUPERFAMILY SSF48179 162 277 6.01E-16 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 Gene3D G3DSA:1.10.1040.10 162 277 7.6E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 Gene3D G3DSA:3.40.50.720 1 161 6.5E-27 T 29-03-2018 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 PIRSF PIRSF000103 1 284 2.5E-64 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 272 8.3E-13 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MSG_RS21995 f6f4965f954a6a9ce59a222b65da00b1 285 SUPERFAMILY SSF51735 6 162 1.0E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.10.450.50 1954 2117 2.6E-4 T 29-03-2018 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.10.450.50 1686 1824 3.1E-6 T 29-03-2018 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.10.450.50 1558 1685 8.0E-7 T 29-03-2018 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.10.180.10 1320 1456 0.21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 262 399 1.5E-11 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:1.25.40.10 99 257 6.0E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:1.25.40.10 820 1094 3.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF48452 99 262 2.16E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF52540 566 710 8.16E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF52540 450 525 8.16E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SMART SM01043 101 244 1.2E-44 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:1.25.40.10 1115 1302 2.2E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:1.10.10.10 2 98 8.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Pfam PF03704 Bacterial transcriptional activator domain 101 243 7.9E-36 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SMART SM00862 21 96 7.7E-9 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 93 3.2E-8 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF55073 258 433 1.73E-43 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.30.70.1230 258 436 1.9E-34 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.10.450.50 1825 1953 4.8E-12 T 29-03-2018 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF48452 1135 1252 7.59E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF54427 1827 1944 5.31E-8 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SUPERFAMILY SSF46894 9 96 3.12E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Gene3D G3DSA:3.40.50.300 453 704 7.3E-8 T 29-03-2018 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 SMART SM00044 220 410 8.2E-5 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS20695 8137f8f78f8f55fc89b4f1bbfad6ab89 2124 Pfam PF13191 AAA ATPase domain 460 630 2.4E-28 T 29-03-2018 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 ProSitePatterns PS00057 Ribosomal protein S18 signature. 30 53 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 TIGRFAM TIGR00165 S18: ribosomal protein bS18 17 81 3.2E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 Gene3D G3DSA:4.10.640.10 1 84 2.2E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 82 20.173 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 Pfam PF01084 Ribosomal protein S18 27 77 9.3E-23 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 SUPERFAMILY SSF46911 9 81 2.62E-25 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 81 3.0E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 PRINTS PR00974 Ribosomal protein S18 family signature 37 47 1.6E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 PRINTS PR00974 Ribosomal protein S18 family signature 69 79 1.6E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 PRINTS PR00974 Ribosomal protein S18 family signature 47 54 1.6E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00385 6e75a8131c6cec9522b352bbb1988774 84 PRINTS PR00974 Ribosomal protein S18 family signature 55 69 1.6E-16 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS24295 728b0925afd0ec44d1c6e852753fbef7 231 SMART SM00855 4 162 1.2E-17 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS24295 728b0925afd0ec44d1c6e852753fbef7 231 Gene3D G3DSA:3.40.50.1240 2 205 6.2E-33 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS24295 728b0925afd0ec44d1c6e852753fbef7 231 SUPERFAMILY SSF53254 2 203 3.34E-40 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS24295 728b0925afd0ec44d1c6e852753fbef7 231 PIRSF PIRSF000709 2 172 2.7E-6 T 29-03-2018 MSG_RS24295 728b0925afd0ec44d1c6e852753fbef7 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 201 3.9E-36 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS02390 70b0946016a1111e14d071a440b15b06 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 96 3.0E-42 T 29-03-2018 MSG_RS02390 70b0946016a1111e14d071a440b15b06 96 Gene3D G3DSA:1.10.287.1060 1 96 5.9E-14 T 29-03-2018 MSG_RS02390 70b0946016a1111e14d071a440b15b06 96 SUPERFAMILY SSF140453 2 95 1.31E-20 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS02390 70b0946016a1111e14d071a440b15b06 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 91 3.0E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS02390 70b0946016a1111e14d071a440b15b06 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 5.8E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS00365 87324017e69af1e813631e05d7283645 448 Gene3D G3DSA:3.30.559.10 8 183 5.8E-4 T 29-03-2018 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Gene3D G3DSA:2.40.50.140 1000 1092 7.9E-11 T 29-03-2018 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1054 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Gene3D G3DSA:1.10.150.280 811 916 1.7E-5 T 29-03-2018 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 SMART SM00481 7 74 1.2E-30 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Pfam PF02811 PHP domain 8 194 4.8E-45 T 29-03-2018 IPR004013 PHP domain GO:0003824 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 316 758 3.5E-158 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Gene3D G3DSA:3.20.20.140 2 269 1.3E-45 T 29-03-2018 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 Pfam PF14579 Helix-hairpin-helix motif 831 918 5.5E-22 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 SUPERFAMILY SSF89550 120 248 2.94E-27 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MSG_RS10995 d7161ca66a06b687efa6cd6388a995c4 1179 SUPERFAMILY SSF89550 6 92 2.94E-27 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 SUPERFAMILY SSF88946 25 93 7.06E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 SUPERFAMILY SSF88659 103 171 3.36E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 Pfam PF04542 Sigma-70 region 2 31 94 2.5E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 Gene3D G3DSA:1.10.10.10 116 176 7.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 171 8.6E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 Pfam PF08281 Sigma-70, region 4 121 171 2.9E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04760 591200c2f7f1f390c301bed090c75816 182 Gene3D G3DSA:1.10.1740.10 23 99 2.8E-12 T 29-03-2018 MSG_RS12365 174d534ff221af93d442683688a310a4 339 SUPERFAMILY SSF51412 5 336 1.98E-46 T 29-03-2018 MSG_RS12365 174d534ff221af93d442683688a310a4 339 Pfam PF03060 Nitronate monooxygenase 9 335 2.0E-69 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS12365 174d534ff221af93d442683688a310a4 339 Gene3D G3DSA:3.20.20.70 1 339 8.4E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS22825 1568b203916546705462f12f66bcbd27 310 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 24 291 5.8E-83 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MSG_RS22825 1568b203916546705462f12f66bcbd27 310 Pfam PF02569 Pantoate-beta-alanine ligase 22 288 4.8E-94 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MSG_RS22825 1568b203916546705462f12f66bcbd27 310 Gene3D G3DSA:3.30.1300.10 191 304 4.4E-33 T 29-03-2018 MSG_RS22825 1568b203916546705462f12f66bcbd27 310 Gene3D G3DSA:3.40.50.620 7 190 1.6E-74 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS22825 1568b203916546705462f12f66bcbd27 310 Hamap MF_00158 Pantothenate synthetase [panC]. 17 290 38.467 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MSG_RS22825 1568b203916546705462f12f66bcbd27 310 SUPERFAMILY SSF52374 15 292 9.5E-102 T 29-03-2018 MSG_RS09445 39d11860e087fa1e92d30b91abce5254 417 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 329 413 7.8E-17 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS09445 39d11860e087fa1e92d30b91abce5254 417 SUPERFAMILY SSF140459 2 174 1.31E-60 T 29-03-2018 MSG_RS09445 39d11860e087fa1e92d30b91abce5254 417 Gene3D G3DSA:1.10.287.1060 19 103 8.4E-7 T 29-03-2018 MSG_RS09445 39d11860e087fa1e92d30b91abce5254 417 Pfam PF00823 PPE family 5 160 7.8E-60 T 29-03-2018 IPR000030 PPE family MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 SUPERFAMILY SSF53383 5 437 1.48E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 Gene3D G3DSA:3.40.640.10 58 315 5.1E-81 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 Pfam PF00202 Aminotransferase class-III 19 432 2.9E-92 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 Gene3D G3DSA:3.90.1150.10 1 57 0.039 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 PIRSF PIRSF000521 21 439 4.6E-25 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS05440 c188178f0e0d50a15f2b51e1fc5b1cdf 443 Gene3D G3DSA:3.90.1150.10 316 443 3.9E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS14450 4f73f9cf18654dbda84ee34731587953 441 Pfam PF01547 Bacterial extracellular solute-binding protein 50 352 5.2E-45 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 MSG_RS14450 4f73f9cf18654dbda84ee34731587953 441 Gene3D G3DSA:3.40.190.10 31 209 5.0E-31 T 29-03-2018 MSG_RS14450 4f73f9cf18654dbda84ee34731587953 441 SUPERFAMILY SSF53850 29 438 3.36E-65 T 29-03-2018 MSG_RS14450 4f73f9cf18654dbda84ee34731587953 441 Gene3D G3DSA:3.40.190.10 230 390 3.4E-10 T 29-03-2018 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 Gene3D G3DSA:3.30.950.10 152 245 8.5E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 3 244 1.2E-108 T 29-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 SUPERFAMILY SSF53790 3 244 4.06E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 Gene3D G3DSA:3.40.1010.10 3 151 2.8E-28 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 PIRSF PIRSF036525 2 246 3.6E-102 T 29-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 MSG_RS20405 d151a805514d114089c920542e23dcf0 246 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 217 3.2E-30 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS01305 a36cb457c7f70b66aca87dbeb9458b1d 201 Gene3D G3DSA:3.40.630.30 2 201 2.3E-39 T 29-03-2018 MSG_RS01305 a36cb457c7f70b66aca87dbeb9458b1d 201 SUPERFAMILY SSF55729 6 198 7.15E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS01305 a36cb457c7f70b66aca87dbeb9458b1d 201 Pfam PF00583 Acetyltransferase (GNAT) family 68 178 1.8E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 170 0.0043 T 29-03-2018 MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 SUPERFAMILY SSF51735 3 217 1.05E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 223 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 5.9E-23 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 3.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 3.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 3.7E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 Gene3D G3DSA:3.40.50.720 2 217 4.0E-50 T 29-03-2018 MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 Pfam PF00106 short chain dehydrogenase 3 180 5.8E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00280 fed05f841b166180bf3f073a5a5ddfe4 223 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 Gene3D G3DSA:3.100.10.10 36 146 9.5E-29 T 29-03-2018 MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 5.5E-31 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 SUPERFAMILY SSF52080 6 144 5.1E-40 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 143 3.5E-47 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 19.358 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MSG_RS04600 8b43c14e9673317718607ad14fc3a25c 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 Pfam PF02567 Phenazine biosynthesis-like protein 156 197 6.4E-5 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 Pfam PF02567 Phenazine biosynthesis-like protein 10 136 5.4E-13 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 PIRSF PIRSF016184 124 221 4.9E-6 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 PIRSF PIRSF016184 1 154 1.6E-21 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 Gene3D G3DSA:3.10.310.10 115 218 1.7E-19 T 29-03-2018 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 Gene3D G3DSA:3.10.310.10 1 114 2.7E-18 T 29-03-2018 MSG_RS08965 31577edf7ae440f66e75e6424dabeec0 228 SUPERFAMILY SSF54506 1 220 8.64E-34 T 29-03-2018 MSG_RS14885 7fa5587aa0e81e80c6c6fd6f2300cd36 283 PIRSF PIRSF028754 1 283 4.0E-124 T 29-03-2018 IPR008492 Protein of unknown function DUF774 MSG_RS14885 7fa5587aa0e81e80c6c6fd6f2300cd36 283 SUPERFAMILY SSF159659 2 253 4.18E-89 T 29-03-2018 MSG_RS14885 7fa5587aa0e81e80c6c6fd6f2300cd36 283 Pfam PF09754 PAC2 family 13 231 5.8E-51 T 29-03-2018 IPR019151 Proteasome assembly chaperone 2 MSG_RS14885 7fa5587aa0e81e80c6c6fd6f2300cd36 283 Gene3D G3DSA:1.10.287.100 212 252 3.1E-10 T 29-03-2018 MSG_RS21095 11e177b5f2d3da826cfa04b9fd0123ca 598 Pfam PF02470 MlaD protein 40 113 3.0E-13 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS21095 11e177b5f2d3da826cfa04b9fd0123ca 598 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 4.0E-63 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 SUPERFAMILY SSF52540 1 224 3.46E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 Gene3D G3DSA:3.40.50.300 276 558 3.9E-21 T 29-03-2018 MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 Gene3D G3DSA:3.40.50.300 1 241 2.5E-16 T 29-03-2018 MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 529 4.8E-14 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 SUPERFAMILY SSF52540 6 50 5.66E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 SUPERFAMILY SSF52540 355 533 5.66E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 576 3.2E-214 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MSG_RS11705 6bba329757fe28bca71dc62dec7b25ca 583 PIRSF PIRSF003128 1 581 3.3E-164 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MSG_RS05870 567da21d6d7e0ee1be26086300b8c48b 494 PIRSF PIRSF006060 7 493 5.4E-89 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS05870 567da21d6d7e0ee1be26086300b8c48b 494 Pfam PF13520 Amino acid permease 31 455 2.2E-57 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS23720 f26f54692cabaf2d8e9a0bb9b01d236b 230 Pfam PF01965 DJ-1/PfpI family 30 227 3.6E-9 T 29-03-2018 IPR002818 DJ-1/PfpI MSG_RS23720 f26f54692cabaf2d8e9a0bb9b01d236b 230 Gene3D G3DSA:3.40.50.880 1 230 1.9E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS23720 f26f54692cabaf2d8e9a0bb9b01d236b 230 SUPERFAMILY SSF52317 2 229 2.93E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 SUPERFAMILY SSF47203 230 372 1.85E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 Gene3D G3DSA:1.20.140.10 222 394 1.2E-15 T 29-03-2018 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 SUPERFAMILY SSF56645 2 208 1.57E-34 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 Gene3D G3DSA:2.40.110.10 115 209 5.0E-17 T 29-03-2018 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 372 1.9E-40 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 89 6.5E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 PIRSF PIRSF016578 1 394 2.4E-139 T 29-03-2018 MSG_RS03940 b8053dd89a2f85655a8454ae3fdb07d3 394 Gene3D G3DSA:1.10.540.10 1 111 1.1E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS11810 120ae7973f2ac94a1504931863937187 115 SUPERFAMILY SSF54637 2 113 5.61E-32 T 29-03-2018 IPR029069 HotDog domain MSG_RS11810 120ae7973f2ac94a1504931863937187 115 PIRSF PIRSF014972 1 115 3.5E-31 T 29-03-2018 IPR025540 Fluoroacetyl-CoA thioesterase MSG_RS11810 120ae7973f2ac94a1504931863937187 115 Gene3D G3DSA:3.10.129.10 1 115 4.0E-23 T 29-03-2018 MSG_RS11810 120ae7973f2ac94a1504931863937187 115 Pfam PF03061 Thioesterase superfamily 24 98 3.9E-5 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 36 222 8.5E-20 T 29-03-2018 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 Pfam PF01553 Acyltransferase 309 434 3.8E-26 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 SUPERFAMILY SSF69593 300 479 4.45E-33 T 29-03-2018 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 Gene3D G3DSA:3.40.1130.10 282 496 6.5E-38 T 29-03-2018 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 Gene3D G3DSA:3.40.50.1000 32 239 1.8E-14 T 29-03-2018 IPR023214 HAD-like domain MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 36 234 2.7E-61 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 Pfam PF12710 haloacid dehalogenase-like hydrolase 36 219 1.1E-29 T 29-03-2018 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 SMART SM00563 323 437 5.3E-31 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS17345 e8b157cb3ec8a94ea53645f7a7e161fe 603 SUPERFAMILY SSF56784 34 223 1.81E-24 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05610 96a50ea71a3c69cf3cc20cc80e4f5a3c 518 SUPERFAMILY SSF51395 15 463 1.99E-107 T 29-03-2018 MSG_RS05610 96a50ea71a3c69cf3cc20cc80e4f5a3c 518 Pfam PF01645 Conserved region in glutamate synthase 142 459 1.7E-71 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MSG_RS05610 96a50ea71a3c69cf3cc20cc80e4f5a3c 518 PIRSF PIRSF006429 8 491 1.7E-135 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein MSG_RS05610 96a50ea71a3c69cf3cc20cc80e4f5a3c 518 Gene3D G3DSA:3.20.20.70 121 466 6.3E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 Gene3D G3DSA:3.40.50.20 192 340 2.0E-21 T 29-03-2018 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 2.1E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 SUPERFAMILY SSF50129 7 171 5.17E-56 T 29-03-2018 IPR011032 GroES-like MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 SMART SM00829 14 341 1.1E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 2.6E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 Gene3D G3DSA:3.90.180.10 1 191 5.0E-57 T 29-03-2018 MSG_RS07445 f8159199d2c7d2e3d8818008476068c3 346 SUPERFAMILY SSF51735 148 311 1.49E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00810 9df5d82b352b2c1536094a83cd0c3185 394 Pfam PF13469 Sulfotransferase family 91 339 5.3E-45 T 29-03-2018 MSG_RS00810 9df5d82b352b2c1536094a83cd0c3185 394 Gene3D G3DSA:3.40.50.300 67 383 6.7E-27 T 29-03-2018 MSG_RS00810 9df5d82b352b2c1536094a83cd0c3185 394 SUPERFAMILY SSF52540 85 136 1.7E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00810 9df5d82b352b2c1536094a83cd0c3185 394 SUPERFAMILY SSF52540 209 355 1.7E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 Gene3D G3DSA:1.10.10.60 52 124 5.6E-13 T 29-03-2018 MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 Gene3D G3DSA:1.10.10.60 4 51 4.7E-18 T 29-03-2018 MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 3.1E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18390 1477d3641a95555907f3d9e3d6331195 189 SUPERFAMILY SSF46689 7 81 3.29E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23575 3e15e647338c5c758b5e2904fe65e16d 57 Gene3D G3DSA:1.10.1470.10 1 57 2.0E-14 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS23575 3e15e647338c5c758b5e2904fe65e16d 57 SUPERFAMILY SSF69047 4 56 1.27E-7 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS23575 3e15e647338c5c758b5e2904fe65e16d 57 Pfam PF05532 CsbD-like 5 57 2.7E-16 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS12215 0eaedf571352b0c80ae168c0d0b46669 115 Pfam PF07681 DoxX 19 72 6.2E-5 T 29-03-2018 IPR032808 DoxX family MSG_RS15940 5ad458c4cf7ec50aa39e103083e6bda5 115 SUPERFAMILY SSF51735 9 42 1.64E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15940 5ad458c4cf7ec50aa39e103083e6bda5 115 SUPERFAMILY SSF51735 71 104 1.64E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15940 5ad458c4cf7ec50aa39e103083e6bda5 115 Gene3D G3DSA:3.40.50.720 9 108 2.6E-8 T 29-03-2018 MSG_RS23990 2da5c8f2d9b0025c7e4e0aaaf908a39e 197 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 24 193 1.0E-28 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS23990 2da5c8f2d9b0025c7e4e0aaaf908a39e 197 SUPERFAMILY SSF109854 14 141 1.74E-7 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS23990 2da5c8f2d9b0025c7e4e0aaaf908a39e 197 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 25 193 2.2E-47 T 29-03-2018 IPR017520 Conserved hypothetical protein CHP03086 MSG_RS23990 2da5c8f2d9b0025c7e4e0aaaf908a39e 197 Gene3D G3DSA:1.20.120.450 13 142 7.7E-10 T 29-03-2018 MSG_RS19190 6fe66dc6d45ff30758520fb6300569fb 278 SUPERFAMILY SSF53335 17 251 3.74E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19190 6fe66dc6d45ff30758520fb6300569fb 278 Pfam PF04072 Leucine carboxyl methyltransferase 21 180 3.4E-14 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS19190 6fe66dc6d45ff30758520fb6300569fb 278 PIRSF PIRSF028177 7 278 2.1E-67 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MSG_RS19190 6fe66dc6d45ff30758520fb6300569fb 278 Gene3D G3DSA:3.40.50.150 2 198 1.3E-31 T 29-03-2018 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 SUPERFAMILY SSF48019 245 361 4.93E-23 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 Gene3D G3DSA:1.20.272.10 243 365 3.0E-19 T 29-03-2018 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 Gene3D G3DSA:3.40.50.300 1 165 1.2E-37 T 29-03-2018 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 Gene3D G3DSA:1.10.8.60 166 242 5.8E-12 T 29-03-2018 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 SMART SM00382 34 177 3.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 360 1.2E-112 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 SUPERFAMILY SSF52540 31 220 8.56E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 Pfam PF13177 DNA polymerase III, delta subunit 17 175 1.3E-37 T 29-03-2018 MSG_RS23475 1729ec3207ce40879d2708c259a716ef 618 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 366 3.8E-14 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MSG_RS05060 59ed3a6439ef8ce9bd178067aa2aaaf9 224 Pfam PF03458 UPF0126 domain 97 169 3.0E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 MSG_RS05060 59ed3a6439ef8ce9bd178067aa2aaaf9 224 Pfam PF03458 UPF0126 domain 10 85 1.8E-20 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 44 76 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 172 7.4E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 SUPERFAMILY SSF88946 17 109 2.79E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 Gene3D G3DSA:1.10.10.10 94 181 3.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 SUPERFAMILY SSF88659 111 174 3.49E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 Gene3D G3DSA:1.10.1740.10 6 92 2.9E-21 T 29-03-2018 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 Pfam PF04545 Sigma-70, region 4 123 171 1.7E-11 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS04710 7f36110e6b499d248e952b4af3db8b23 181 Pfam PF04542 Sigma-70 region 2 22 89 5.7E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 3.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 Gene3D G3DSA:1.10.10.60 1 62 2.4E-16 T 29-03-2018 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 SUPERFAMILY SSF48498 93 186 3.11E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 Gene3D G3DSA:1.10.357.10 63 189 3.6E-20 T 29-03-2018 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 SUPERFAMILY SSF46689 4 77 1.45E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07385 3cce8fe9a556c9dfc2f732442252e777 189 Pfam PF13305 WHG domain 99 165 3.1E-6 T 29-03-2018 IPR025996 WHG domain MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 SUPERFAMILY SSF55781 70 224 3.27E-23 T 29-03-2018 IPR029016 GAF domain-like MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 Pfam PF09339 IclR helix-turn-helix domain 10 58 5.6E-9 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 Gene3D G3DSA:1.10.10.10 3 78 1.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 Gene3D G3DSA:3.30.450.40 158 225 6.0E-8 T 29-03-2018 IPR029016 GAF domain-like MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 Gene3D G3DSA:3.30.450.40 79 157 1.7E-13 T 29-03-2018 IPR029016 GAF domain-like MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 SMART SM00346 8 95 5.0E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS21475 056b0fe0ce39601f20699ef1be0e0662 225 SUPERFAMILY SSF46785 9 79 4.12E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 448 6.5E-146 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 SUPERFAMILY SSF54211 299 454 8.34E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 SUPERFAMILY SSF54211 251 265 8.34E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 Gene3D G3DSA:3.30.230.10 282 453 1.6E-21 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 Pfam PF13541 Subunit ChlI of Mg-chelatase 359 424 1.3E-6 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 Gene3D G3DSA:3.40.50.300 70 278 5.1E-44 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 SMART SM00382 86 240 4.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 Pfam PF13481 AAA domain 78 218 1.3E-16 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 SUPERFAMILY SSF52540 68 289 2.67E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 Hamap MF_01498 DNA repair protein RadA [radA]. 21 453 41.683 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 120 137 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 170 194 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 78 106 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 318 341 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 10 34 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 209 237 1.6E-78 T 29-03-2018 MSG_RS22745 39be2a2b6ee2d0b2f7b9a4e23cceaf59 471 PRINTS PR01874 DNA repair protein radA signature 244 270 1.6E-78 T 29-03-2018 MSG_RS06715 1bbb5a5bf654af782ada4e354a9b9b01 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.705 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 MSG_RS06715 1bbb5a5bf654af782ada4e354a9b9b01 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.9E-24 T 29-03-2018 MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.1E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 Gene3D G3DSA:3.40.50.720 7 265 1.1E-70 T 29-03-2018 MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 2.6E-65 T 29-03-2018 MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21420 d28feb6013a2dfde5c64da34a1dedd68 274 SUPERFAMILY SSF51735 6 257 1.37E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 PIRSF PIRSF000103 1 270 4.6E-59 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 Gene3D G3DSA:3.40.50.720 1 172 1.4E-30 T 29-03-2018 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 SUPERFAMILY SSF51735 1 162 5.82E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 SUPERFAMILY SSF48179 162 253 2.61E-16 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 262 3.8E-17 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 Gene3D G3DSA:1.10.1040.10 173 271 4.7E-17 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS21240 852ee27ae2b3e160d2dec72216b433f6 271 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 8.0E-40 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS06805 d198a370e39feb5a55b50e1d22f2f347 300 SUPERFAMILY SSF51569 2 296 2.34E-55 T 29-03-2018 MSG_RS06805 d198a370e39feb5a55b50e1d22f2f347 300 Gene3D G3DSA:3.20.20.70 1 297 4.2E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS06805 d198a370e39feb5a55b50e1d22f2f347 300 Pfam PF00682 HMGL-like 4 272 5.5E-37 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MSG_RS02160 d6ee08869a0e1658d3e4838c08c70637 422 Pfam PF00654 Voltage gated chloride channel 98 386 2.4E-41 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS02160 d6ee08869a0e1658d3e4838c08c70637 422 Gene3D G3DSA:1.10.3080.10 5 411 2.0E-40 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MSG_RS02160 d6ee08869a0e1658d3e4838c08c70637 422 PRINTS PR00762 Chloride channel signature 107 126 1.8E-6 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS02160 d6ee08869a0e1658d3e4838c08c70637 422 PRINTS PR00762 Chloride channel signature 159 178 1.8E-6 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MSG_RS02160 d6ee08869a0e1658d3e4838c08c70637 422 SUPERFAMILY SSF81340 15 408 1.27E-52 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 SMART SM00899 152 230 9.8E-10 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 5.9E-30 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Gene3D G3DSA:1.10.60.10 75 129 5.9E-27 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Gene3D G3DSA:2.30.30.90 130 230 1.1E-16 T 29-03-2018 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 SUPERFAMILY SSF47979 65 134 3.01E-27 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Pfam PF04023 FeoA domain 152 229 1.5E-7 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Gene3D G3DSA:1.10.10.10 1 73 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 SUPERFAMILY SSF50037 130 231 4.35E-22 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 SUPERFAMILY SSF46785 2 62 2.36E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 SMART SM00529 26 125 2.6E-47 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MSG_RS08995 e50109417cb1693cb6351614802bbffa 231 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 1.3E-21 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 3.5E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 Gene3D G3DSA:3.40.50.2300 2 131 7.2E-37 T 29-03-2018 MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 Gene3D G3DSA:1.10.10.10 132 234 3.0E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 SUPERFAMILY SSF52172 7 187 1.57E-40 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 Pfam PF00072 Response regulator receiver domain 11 120 2.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 SMART SM00448 9 120 6.6E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS23900 bf5841bbe8d9bbf851bf56bb59bd45a5 234 SMART SM00862 156 230 9.7E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS05240 2390ad7357ef95f0e5116cec8a95ae9b 214 Pfam PF00881 Nitroreductase family 13 189 9.5E-22 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS05240 2390ad7357ef95f0e5116cec8a95ae9b 214 Gene3D G3DSA:3.40.109.10 4 214 7.6E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS05240 2390ad7357ef95f0e5116cec8a95ae9b 214 SUPERFAMILY SSF55469 7 69 2.88E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS05240 2390ad7357ef95f0e5116cec8a95ae9b 214 SUPERFAMILY SSF55469 103 214 2.88E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS11020 9afe812c910db716e1d26784737b4cbc 217 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 23 166 1.7E-43 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MSG_RS11020 9afe812c910db716e1d26784737b4cbc 217 Gene3D G3DSA:2.30.110.10 1 185 2.4E-45 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS11020 9afe812c910db716e1d26784737b4cbc 217 SUPERFAMILY SSF50475 4 187 3.34E-58 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS22670 be5b1d00a68696f67809d2d3f66a514d 309 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 296 1.7E-46 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MSG_RS22670 be5b1d00a68696f67809d2d3f66a514d 309 Gene3D G3DSA:3.40.50.1980 179 301 2.6E-20 T 29-03-2018 MSG_RS22670 be5b1d00a68696f67809d2d3f66a514d 309 SUPERFAMILY SSF53807 34 301 1.23E-56 T 29-03-2018 MSG_RS22670 be5b1d00a68696f67809d2d3f66a514d 309 Gene3D G3DSA:3.40.50.1980 36 178 5.1E-34 T 29-03-2018 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 SUPERFAMILY SSF89447 2 134 5.83E-43 T 29-03-2018 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 73 140 7.7E-23 T 29-03-2018 IPR020603 MraZ domain MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 71 5.3E-20 T 29-03-2018 IPR020603 MraZ domain MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 48.28 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 136 1.7E-31 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 Gene3D G3DSA:2.10.260.10 4 27 1.2E-5 T 29-03-2018 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 Gene3D G3DSA:2.10.260.10 80 123 6.4E-5 T 29-03-2018 MSG_RS15165 8109ebd1c9ab05b14b6d3251074d944c 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 2.0E-68 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MSG_RS17720 b7504f89039fdc70cad61995cb9b9d77 290 SUPERFAMILY SSF51679 4 279 3.83E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS17720 b7504f89039fdc70cad61995cb9b9d77 290 Gene3D G3DSA:3.20.20.30 219 282 0.042 T 29-03-2018 MSG_RS17720 b7504f89039fdc70cad61995cb9b9d77 290 Pfam PF00296 Luciferase-like monooxygenase 14 197 6.2E-33 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS17720 b7504f89039fdc70cad61995cb9b9d77 290 Gene3D G3DSA:3.20.20.30 9 218 1.2E-37 T 29-03-2018 MSG_RS15275 21ad6bd8dec719b40e5cce743f46e008 382 Pfam PF00877 NlpC/P60 family 282 367 1.5E-23 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MSG_RS15275 21ad6bd8dec719b40e5cce743f46e008 382 Gene3D G3DSA:3.90.1720.10 267 382 1.4E-36 T 29-03-2018 MSG_RS15275 21ad6bd8dec719b40e5cce743f46e008 382 SUPERFAMILY SSF54001 266 380 2.31E-37 T 29-03-2018 MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 3 333 1.9E-215 T 29-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 Gene3D G3DSA:3.20.20.30 1 335 2.7E-79 T 29-03-2018 MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 Hamap MF_02123 F420-dependent glucose-6-phosphate dehydrogenase [fgd]. 3 335 69.557 T 29-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 SUPERFAMILY SSF51679 4 333 2.0E-73 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 6 333 4.5E-78 T 29-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related MSG_RS02965 5af50cccc87c791d22aed836b8d5d9e8 336 Pfam PF00296 Luciferase-like monooxygenase 11 307 4.1E-69 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 Pfam PF00561 alpha/beta hydrolase fold 26 279 8.7E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 PRINTS PR00412 Epoxide hydrolase signature 113 126 1.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 PRINTS PR00412 Epoxide hydrolase signature 272 294 1.8E-7 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 Gene3D G3DSA:3.40.50.1820 3 297 2.5E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00140 915444e1b6a909e2a0a03d1a7f23f38c 298 SUPERFAMILY SSF53474 7 293 2.2E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 305 332 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 354 363 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 166 181 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 149 165 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 103 114 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 288 299 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 363 374 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 PRINTS PR00359 B-class P450 signature 333 348 4.6E-24 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 Pfam PF00067 Cytochrome P450 219 383 4.4E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 SUPERFAMILY SSF48264 21 415 3.27E-71 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21150 a932838f4a6270c2bf307d27d70848dd 453 Gene3D G3DSA:1.10.630.10 3 415 4.4E-59 T 29-03-2018 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 1.4E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 SMART SM00829 14 363 0.0088 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 Gene3D G3DSA:3.40.50.10730 175 309 2.7E-31 T 29-03-2018 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 Pfam PF00107 Zinc-binding dehydrogenase 190 325 1.1E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 Gene3D G3DSA:3.90.180.10 2 174 1.8E-44 T 29-03-2018 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 SUPERFAMILY SSF50129 315 364 4.14E-8 T 29-03-2018 IPR011032 GroES-like MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 SUPERFAMILY SSF50129 4 186 1.48E-53 T 29-03-2018 IPR011032 GroES-like MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 365 1.3E-207 T 29-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 MSG_RS15810 718cf8f10dd840fcdd743c7211dd7e8a 365 SUPERFAMILY SSF51735 153 330 3.2E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Gene3D G3DSA:1.10.1390.10 514 554 1.1E-16 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 49 525 41.007 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Gene3D G3DSA:3.40.50.10490 147 261 1.5E-52 T 29-03-2018 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Gene3D G3DSA:3.40.50.10490 262 513 5.4E-112 T 29-03-2018 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Gene3D G3DSA:3.40.50.10490 2 146 4.5E-45 T 29-03-2018 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 SUPERFAMILY SSF53697 9 549 2.56E-202 T 29-03-2018 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 268 281 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 153 172 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 282 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 341 362 3.7E-55 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS20375 4ef85ea6f3206574ba2d7ba405507671 554 Pfam PF00342 Phosphoglucose isomerase 55 543 2.1E-200 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 Gene3D G3DSA:3.40.50.150 69 265 2.3E-39 T 29-03-2018 MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 237 2.7E-18 T 29-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 SUPERFAMILY SSF53335 7 260 2.07E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 PIRSF PIRSF017269 1 269 1.4E-85 T 29-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 Gene3D G3DSA:3.10.330.20 7 67 1.3E-22 T 29-03-2018 MSG_RS14790 f9987d9187e548b31ce42fbb951fd4f7 280 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 4 54 1.4E-26 T 29-03-2018 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 Gene3D G3DSA:1.10.630.10 4 416 5.7E-69 T 29-03-2018 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 101 112 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 165 180 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 290 301 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 307 334 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 335 350 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 365 376 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 209 231 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 148 164 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00359 B-class P450 signature 356 365 8.7E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 358 367 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00385 P450 superfamily signature 255 272 1.0E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00385 P450 superfamily signature 356 365 1.0E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 PRINTS PR00385 P450 superfamily signature 365 376 1.0E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 SUPERFAMILY SSF48264 22 416 2.36E-87 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 Pfam PF00067 Cytochrome P450 291 383 1.9E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16320 6b383207344863c8782307c337c9e3d9 416 Pfam PF00067 Cytochrome P450 99 283 7.0E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS02555 7b34c469427fae6e9f4777f390279516 254 Gene3D G3DSA:3.40.50.1820 1 248 1.6E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02555 7b34c469427fae6e9f4777f390279516 254 SUPERFAMILY SSF53474 3 137 3.24E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02555 7b34c469427fae6e9f4777f390279516 254 SUPERFAMILY SSF53474 181 251 3.24E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02555 7b34c469427fae6e9f4777f390279516 254 Pfam PF12146 Serine aminopeptidase, S33 31 137 1.5E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 452 471 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 289 303 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 329 344 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 367 381 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 381 400 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 517 529 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 414 426 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 PRINTS PR00819 CbxX/CfqX superfamily signature 435 452 3.2E-53 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 Gene3D G3DSA:3.40.50.300 327 511 8.2E-21 T 29-03-2018 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 Gene3D G3DSA:1.25.40.10 21 326 3.4E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 27 566 7.7E-216 T 29-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 SMART SM00382 326 467 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 SUPERFAMILY SSF52540 291 533 1.01E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24480 b4992348ad20ecfff2e114e085c27342 573 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 330 464 5.5E-22 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS00400 51bd31bf4a52c8b30602bb5011430e1d 160 Pfam PF14081 Domain of unknown function (DUF4262) 22 139 1.8E-32 T 29-03-2018 IPR025358 Protein of unknown function DUF4262 MSG_RS09950 9c879510c8eaff8dce1fde4170cd33de 172 Pfam PF01029 NusB family 12 139 7.9E-36 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS09950 9c879510c8eaff8dce1fde4170cd33de 172 Gene3D G3DSA:1.10.940.10 7 142 8.4E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS09950 9c879510c8eaff8dce1fde4170cd33de 172 SUPERFAMILY SSF48013 11 139 1.26E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS09950 9c879510c8eaff8dce1fde4170cd33de 172 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 11 140 1.1E-38 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 MSG_RS09950 9c879510c8eaff8dce1fde4170cd33de 172 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 9 144 22.066 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 7.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 SMART SM00862 148 224 3.9E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 SUPERFAMILY SSF52172 1 185 1.25E-43 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 Pfam PF00072 Response regulator receiver domain 4 112 2.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 SMART SM00448 2 112 1.9E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 Gene3D G3DSA:1.10.10.10 125 226 1.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19825 fd18132a76aa019242a77e998990adb0 226 Gene3D G3DSA:3.40.50.2300 1 124 3.2E-37 T 29-03-2018 MSG_RS23845 856dd1fc7d955e134c2ca34768cf01a0 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 182 2.5E-36 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS23845 856dd1fc7d955e134c2ca34768cf01a0 202 Gene3D G3DSA:3.40.50.1240 1 194 2.6E-35 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS23845 856dd1fc7d955e134c2ca34768cf01a0 202 SUPERFAMILY SSF53254 1 194 5.62E-38 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS23845 856dd1fc7d955e134c2ca34768cf01a0 202 SMART SM00855 2 150 8.2E-14 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS20025 1fb0736c3bb9d1dd7e0f76562968f861 564 Pfam PF01266 FAD dependent oxidoreductase 17 295 8.8E-7 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS20025 1fb0736c3bb9d1dd7e0f76562968f861 564 Gene3D G3DSA:3.50.50.60 6 563 5.7E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20025 1fb0736c3bb9d1dd7e0f76562968f861 564 SUPERFAMILY SSF51905 12 270 2.05E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20025 1fb0736c3bb9d1dd7e0f76562968f861 564 SUPERFAMILY SSF51905 496 555 2.05E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20025 1fb0736c3bb9d1dd7e0f76562968f861 564 Pfam PF05199 GMC oxidoreductase 418 547 8.8E-22 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 SUPERFAMILY SSF56112 13 294 1.6E-68 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 Pfam PF00069 Protein kinase domain 16 263 3.0E-42 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 Gene3D G3DSA:3.30.200.20 6 114 1.8E-19 T 29-03-2018 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 SMART SM00220 16 276 4.6E-51 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 Gene3D G3DSA:1.10.510.10 115 366 2.3E-41 T 29-03-2018 MSG_RS12045 d00fdfd7f4dd74df425491f11bb8cc4c 510 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Gene3D G3DSA:1.10.10.60 80 113 2.5E-4 T 29-03-2018 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Pfam PF00665 Integrase core domain 138 275 3.5E-26 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Gene3D G3DSA:3.30.420.10 132 316 1.4E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 SUPERFAMILY SSF46689 9 108 7.88E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 SUPERFAMILY SSF53098 138 315 7.33E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Gene3D G3DSA:1.10.10.10 4 40 4.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Pfam PF13011 leucine-zipper of insertion element IS481 2 81 5.8E-21 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS03950 c9f2ea48a4125399482fdcb306f9414a 316 Gene3D G3DSA:1.10.10.10 41 79 0.21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Gene3D G3DSA:3.40.630.30 137 297 2.0E-40 T 29-03-2018 MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 SUPERFAMILY SSF55718 304 405 1.06E-14 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Pfam PF13530 Sterol carrier protein domain 181 400 3.2E-46 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Pfam PF13527 Acetyltransferase (GNAT) domain 10 132 1.2E-18 T 29-03-2018 MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Gene3D G3DSA:3.30.1050.10 298 398 2.6E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 SUPERFAMILY SSF55729 5 303 1.04E-55 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Hamap MF_01812 UPF0256 protein . 2 405 29.77 T 29-03-2018 IPR022902 N-acetyltransferase Eis MSG_RS00655 e8f38a272c4a0c88bcfa4c4d7a2a086b 405 Gene3D G3DSA:3.40.630.30 2 136 1.0E-13 T 29-03-2018 MSG_RS03430 f60dbf01d91c89ba91df82a9973ac74d 170 Gene3D G3DSA:3.30.530.20 1 162 9.9E-5 T 29-03-2018 IPR023393 START-like domain MSG_RS03430 f60dbf01d91c89ba91df82a9973ac74d 170 Pfam PF10698 Protein of unknown function (DUF2505) 7 166 1.4E-48 T 29-03-2018 IPR019639 Protein of unknown function DUF2505 MSG_RS15565 f0f7389d03ff6b1db97aa8934bdfdfd5 354 SUPERFAMILY SSF53383 22 340 5.11E-51 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS15565 f0f7389d03ff6b1db97aa8934bdfdfd5 354 Gene3D G3DSA:3.40.640.10 49 232 5.5E-20 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS15565 f0f7389d03ff6b1db97aa8934bdfdfd5 354 Gene3D G3DSA:3.90.1150.10 233 331 2.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS15565 f0f7389d03ff6b1db97aa8934bdfdfd5 354 Pfam PF00155 Aminotransferase class I and II 63 324 5.0E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS15565 f0f7389d03ff6b1db97aa8934bdfdfd5 354 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 201 214 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MSG_RS06090 92f1b18c746ce13a70b3d9c73f83e5e6 278 Gene3D G3DSA:3.40.640.10 103 257 5.6E-7 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS06090 92f1b18c746ce13a70b3d9c73f83e5e6 278 SUPERFAMILY SSF53383 27 245 3.13E-26 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS06090 92f1b18c746ce13a70b3d9c73f83e5e6 278 Pfam PF02347 Glycine cleavage system P-protein 26 236 3.7E-23 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 Gene3D G3DSA:3.40.47.10 212 356 2.8E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 PIRSF PIRSF000451 1 356 2.3E-111 T 29-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 218 354 2.1E-13 T 29-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 SUPERFAMILY SSF53901 3 355 2.39E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 ProSitePatterns PS00441 Chalcone and stilbene synthases active site. 130 146 - T 29-03-2018 IPR018088 Chalcone/stilbene synthase, active site GO:0009058|GO:0016746 KEGG: 00941+2.3.1.74|MetaCyc: PWY-5135|MetaCyc: PWY-6316|MetaCyc: PWY-6787|MetaCyc: PWY-7397 MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 9 197 1.2E-21 T 29-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal MSG_RS11555 f3f8cb40f2c6a633cc7bab00d6ee6c39 356 Gene3D G3DSA:3.40.47.10 1 208 2.8E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 84 4.0E-31 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 SUPERFAMILY SSF51344 4 85 5.36E-19 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 Gene3D G3DSA:2.60.15.10 1 90 1.6E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 119 17.208 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 3.3E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18240 a43fe23dc4850195c9f3a02bc27185d5 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 98 6.4E-25 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS21465 b37334dd1277cec91196339851776f93 570 SUPERFAMILY SSF51905 270 384 2.95E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21465 b37334dd1277cec91196339851776f93 570 SUPERFAMILY SSF51905 12 183 2.95E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21465 b37334dd1277cec91196339851776f93 570 Gene3D G3DSA:3.50.50.60 9 376 1.9E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21465 b37334dd1277cec91196339851776f93 570 Pfam PF01494 FAD binding domain 12 348 1.2E-76 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS21465 b37334dd1277cec91196339851776f93 570 Hamap MF_01652 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase [mhpA]. 3 556 62.88 T 29-03-2018 IPR023786 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase GO:0008688|GO:0019622|GO:0055114 KEGG: 00360+1.14.13.127|KEGG: 00362+1.14.13.12|KEGG: 00627+1.14.13.12|MetaCyc: PWY-6690 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.8E-38 T 29-03-2018 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 1.8E-38 T 29-03-2018 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 334 1.8E-38 T 29-03-2018 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.8E-38 T 29-03-2018 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 1.8E-38 T 29-03-2018 MSG_RS21465 b37334dd1277cec91196339851776f93 570 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 1.8E-38 T 29-03-2018 MSG_RS13340 15e76fa22a7d945e564f18fa1ca36999 160 SUPERFAMILY SSF69118 31 153 4.32E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS13340 15e76fa22a7d945e564f18fa1ca36999 160 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 104 4.1E-7 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13340 15e76fa22a7d945e564f18fa1ca36999 160 Gene3D G3DSA:1.20.1290.10 13 159 5.0E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 SMART SM00939 320 545 6.8E-59 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 SUPERFAMILY SSF49785 347 548 1.28E-49 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 SUPERFAMILY SSF53474 35 353 1.31E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 Gene3D G3DSA:2.60.120.260 347 549 4.2E-51 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 42 548 1.1E-83 T 29-03-2018 IPR005674 CocE/Serine esterase GO:0016787 MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 335 537 9.0E-31 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 46 306 4.4E-60 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MSG_RS08575 d2ad55207c8a88f5a64b6568cc137cbf 566 Gene3D G3DSA:3.40.50.1820 31 346 8.4E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13615 ba4bec779d750dfe88f7356a7e69270e 149 SUPERFAMILY SSF46785 9 143 2.05E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13615 ba4bec779d750dfe88f7356a7e69270e 149 Gene3D G3DSA:2.20.70.10 84 104 0.02 T 29-03-2018 MSG_RS13615 ba4bec779d750dfe88f7356a7e69270e 149 Pfam PF01475 Ferric uptake regulator family 18 107 6.1E-19 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MSG_RS13615 ba4bec779d750dfe88f7356a7e69270e 149 Gene3D G3DSA:1.10.10.10 10 83 8.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06150 bd618d562536ead81a035c65af7b9c8a 294 Pfam PF02353 Mycolic acid cyclopropane synthetase 12 289 1.2E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS06150 bd618d562536ead81a035c65af7b9c8a 294 PIRSF PIRSF003085 2 294 2.0E-111 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS06150 bd618d562536ead81a035c65af7b9c8a 294 SUPERFAMILY SSF53335 19 293 3.7E-75 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS06150 bd618d562536ead81a035c65af7b9c8a 294 Gene3D G3DSA:3.40.50.150 8 293 3.3E-58 T 29-03-2018 MSG_RS04820 38159869be1e2bdac4ca5853b6278e9e 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.9E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MSG_RS04820 38159869be1e2bdac4ca5853b6278e9e 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.2E-28 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MSG_RS04820 38159869be1e2bdac4ca5853b6278e9e 73 Gene3D G3DSA:2.40.50.140 1 73 7.1E-37 T 29-03-2018 MSG_RS04820 38159869be1e2bdac4ca5853b6278e9e 73 SUPERFAMILY SSF50249 4 72 1.47E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS04820 38159869be1e2bdac4ca5853b6278e9e 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.479 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 PIRSF PIRSF002144 1 93 4.0E-32 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 Gene3D G3DSA:3.30.860.10 1 92 1.0E-39 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.6E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.166 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 SUPERFAMILY SSF54570 3 83 5.62E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 7.3E-48 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04480 e007f9b9591ff245d8d5d849433b9832 93 Pfam PF00203 Ribosomal protein S19 3 83 9.7E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 SUPERFAMILY SSF47060 3 89 2.77E-34 T 29-03-2018 IPR009068 S15/NS1, RNA-binding MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 Gene3D G3DSA:1.10.287.10 2 89 7.9E-35 T 29-03-2018 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.245 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 4.0E-27 T 29-03-2018 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 6.5E-40 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 SMART SM01387 8 88 2.2E-47 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08625 a1f423b02263a2cf92f855d47dfa565e 89 Pfam PF00312 Ribosomal protein S15 8 88 1.3E-35 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS16630 8ee99326192406578d6b784bcc9390b3 199 Gene3D G3DSA:2.60.40.200 51 196 1.2E-21 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS16630 8ee99326192406578d6b784bcc9390b3 199 SUPERFAMILY SSF49329 56 196 1.27E-30 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS16630 8ee99326192406578d6b784bcc9390b3 199 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 64 195 1.3E-20 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS11860 a78580af751bac9b81e0f535788be74b 95 Gene3D G3DSA:3.40.50.720 3 87 1.6E-11 T 29-03-2018 MSG_RS11860 a78580af751bac9b81e0f535788be74b 95 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 77 1.4E-9 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS11860 a78580af751bac9b81e0f535788be74b 95 SUPERFAMILY SSF51735 3 82 3.05E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11860 a78580af751bac9b81e0f535788be74b 95 SMART SM00846 3 91 4.9E-4 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 SUPERFAMILY SSF46689 269 319 7.89E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 Gene3D G3DSA:1.10.10.60 234 274 6.3E-8 T 29-03-2018 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 Gene3D G3DSA:3.40.50.880 5 233 4.0E-61 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 Gene3D G3DSA:1.10.10.60 275 323 3.6E-9 T 29-03-2018 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 Pfam PF01965 DJ-1/PfpI family 11 177 2.3E-26 T 29-03-2018 IPR002818 DJ-1/PfpI MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 SUPERFAMILY SSF52317 11 197 1.11E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 SUPERFAMILY SSF46689 218 266 3.66E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 311 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 Pfam PF12833 Helix-turn-helix domain 239 317 1.3E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS06345 c0e46adf95a2756bd9452c602371ec68 323 SMART SM00342 233 315 5.6E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MSG_RS22290 a1965d8de07d81a7166794cefa3039fa 254 Pfam PF02405 Permease MlaE 36 247 1.0E-60 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 Pfam PF00186 Dihydrofolate reductase 4 162 2.5E-43 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 15 37 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 PRINTS PR00070 Dihydrofolate reductase signature 96 110 4.9E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 PRINTS PR00070 Dihydrofolate reductase signature 42 53 4.9E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 PRINTS PR00070 Dihydrofolate reductase signature 15 25 4.9E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 PRINTS PR00070 Dihydrofolate reductase signature 29 37 4.9E-15 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 SUPERFAMILY SSF53597 4 164 1.43E-47 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 Gene3D G3DSA:3.40.430.10 39 165 1.9E-30 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 Gene3D G3DSA:3.40.430.10 1 38 2.8E-11 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS08770 da46d32277e90bc259ea923b89a90504 165 PIRSF PIRSF000194 1 165 2.0E-46 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MSG_RS09350 f2fd9c9f3b98432b184251f9af3734a9 492 Pfam PF03354 Phage Terminase 74 261 5.2E-8 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type MSG_RS09350 f2fd9c9f3b98432b184251f9af3734a9 492 Pfam PF03354 Phage Terminase 360 469 5.7E-6 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type MSG_RS09350 f2fd9c9f3b98432b184251f9af3734a9 492 SUPERFAMILY SSF52540 44 199 3.15E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09350 f2fd9c9f3b98432b184251f9af3734a9 492 Gene3D G3DSA:3.40.50.300 35 222 1.9E-4 T 29-03-2018 MSG_RS13630 b6c0cc4d37279834655945fe593c6e0a 143 Gene3D G3DSA:2.30.110.10 4 129 2.1E-14 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13630 b6c0cc4d37279834655945fe593c6e0a 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 87 2.0E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS13630 b6c0cc4d37279834655945fe593c6e0a 143 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 6 133 1.4E-35 T 29-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative MSG_RS13630 b6c0cc4d37279834655945fe593c6e0a 143 SUPERFAMILY SSF50475 8 131 7.3E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 SUPERFAMILY SSF46955 18 98 7.33E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 Gene3D G3DSA:1.10.1660.10 14 71 3.7E-21 T 29-03-2018 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 30 1.8E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 53 73 1.8E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 30 43 1.8E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 Pfam PF13411 MerR HTH family regulatory protein 18 84 6.7E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 SMART SM00422 18 86 1.0E-25 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS06460 e28ef3a3dcaf1e5c7f289e8b2ad4a099 123 Gene3D G3DSA:1.10.1660.10 72 120 8.1E-6 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Pfam PF00702 haloacid dehalogenase-like hydrolase 439 651 2.9E-46 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 656 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 293 307 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 594 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 562 573 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 443 457 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 660 672 2.7E-24 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Gene3D G3DSA:3.40.1110.10 457 564 1.8E-29 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Gene3D G3DSA:3.30.70.100 13 82 3.0E-20 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 ProSitePatterns PS01047 Heavy-metal-associated domain. 22 50 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF81665 170 246 2.75E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF81665 344 434 2.75E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF81653 248 343 1.28E-18 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00940 Cation-transporting P-type ATPase A signature 111 128 3.5E-39 T 29-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00940 Cation-transporting P-type ATPase A signature 246 265 3.5E-39 T 29-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00940 Cation-transporting P-type ATPase A signature 193 210 3.5E-39 T 29-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 PRINTS PR00940 Cation-transporting P-type ATPase A signature 93 111 3.5E-39 T 29-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Pfam PF00403 Heavy-metal-associated domain 20 78 6.2E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 718 7.9E-77 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 166 739 3.5E-167 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF56784 441 461 4.08E-51 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF56784 496 737 4.08E-51 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Pfam PF00122 E1-E2 ATPase 245 421 3.6E-47 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 SUPERFAMILY SSF55008 16 85 5.11E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 445 451 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Gene3D G3DSA:3.40.50.1000 565 701 3.2E-33 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 Gene3D G3DSA:1.20.1110.10 204 456 2.7E-39 T 29-03-2018 MSG_RS15610 9c590b1e9b9b2beb0340157c8a8276c0 753 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 206 740 3.0E-145 T 29-03-2018 MSG_RS08320 00b27c4bf2151ba20070bbfaa22373a8 469 Gene3D G3DSA:3.90.1300.10 8 468 2.5E-102 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS08320 00b27c4bf2151ba20070bbfaa22373a8 469 SUPERFAMILY SSF75304 8 459 1.09E-104 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS08320 00b27c4bf2151ba20070bbfaa22373a8 469 Pfam PF01425 Amidase 33 450 4.7E-104 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS13740 290be5b676dcdca28d720a95d6cc4060 72 Pfam PF05305 Protein of unknown function (DUF732) 2 61 5.6E-6 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS01470 e53de773cce105daa31d1ac46863669b 125 Pfam PF04248 Domain of unknown function (DUF427) 24 116 8.1E-33 T 29-03-2018 IPR007361 Domain of unknown function DUF427 MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 SUPERFAMILY SSF52172 159 224 5.47E-9 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 PIRSF PIRSF036625 2 233 1.6E-57 T 29-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 Gene3D G3DSA:1.10.10.10 178 226 2.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 Pfam PF13185 GAF domain 33 164 1.7E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 SUPERFAMILY SSF55781 32 174 1.05E-17 T 29-03-2018 IPR029016 GAF domain-like MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 Pfam PF03861 ANTAR domain 172 224 1.7E-19 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 SMART SM01012 169 224 2.0E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS06470 6a5938c7d7baed726d9c1dbcc3ac79a1 233 Gene3D G3DSA:3.30.450.40 2 177 1.1E-18 T 29-03-2018 IPR029016 GAF domain-like MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 Pfam PF02515 CoA-transferase family III 414 794 5.7E-102 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 Pfam PF02515 CoA-transferase family III 28 391 2.0E-67 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 SUPERFAMILY SSF89796 409 817 1.7E-109 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 Gene3D G3DSA:3.40.50.10540 408 824 2.8E-116 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 Gene3D G3DSA:3.40.50.10540 22 399 3.5E-78 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21385 eb9dbdc545a5cd56677ed26bb9e51b54 827 SUPERFAMILY SSF89796 25 394 1.57E-75 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS07280 350e6323004f8eddd6e96f221088e674 323 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 14 160 5.0E-28 T 29-03-2018 IPR025847 MEDS domain MSG_RS07280 350e6323004f8eddd6e96f221088e674 323 Gene3D G3DSA:3.30.565.10 188 322 5.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS07280 350e6323004f8eddd6e96f221088e674 323 Pfam PF13581 Histidine kinase-like ATPase domain 202 310 4.5E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS07280 350e6323004f8eddd6e96f221088e674 323 SUPERFAMILY SSF55874 213 313 1.23E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 SUPERFAMILY SSF54631 286 413 3.28E-23 T 29-03-2018 MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Gene3D G3DSA:2.30.30.240 7 78 2.5E-5 T 29-03-2018 MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Gene3D G3DSA:3.10.580.10 275 419 1.7E-18 T 29-03-2018 MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 SUPERFAMILY SSF158791 171 282 6.28E-28 T 29-03-2018 MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Pfam PF03448 MgtE intracellular N domain 186 285 5.9E-24 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 SMART SM00924 184 287 8.8E-33 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Pfam PF00571 CBS domain 288 349 0.0028 T 29-03-2018 IPR000644 CBS domain MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Pfam PF00571 CBS domain 359 411 8.4E-5 T 29-03-2018 IPR000644 CBS domain MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 SUPERFAMILY SSF50346 10 89 1.49E-6 T 29-03-2018 IPR011033 PRC-barrel-like MSG_RS18770 ec93abc1de66019d075fcfda06420699 433 Gene3D G3DSA:1.25.60.10 165 274 3.1E-22 T 29-03-2018 MSG_RS06755 05cb91a53883f3576960217b25db59d4 242 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 100 221 2.1E-44 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06755 05cb91a53883f3576960217b25db59d4 242 SUPERFAMILY SSF143243 84 237 3.53E-47 T 29-03-2018 MSG_RS06755 05cb91a53883f3576960217b25db59d4 242 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 73 230 28.6 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06755 05cb91a53883f3576960217b25db59d4 242 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 150 203 5.0E-24 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06755 05cb91a53883f3576960217b25db59d4 242 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 101 222 6.9E-41 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 Pfam PF01174 SNO glutamine amidotransferase family 8 193 1.2E-54 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 Gene3D G3DSA:3.40.50.880 4 198 4.2E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 SUPERFAMILY SSF52317 3 194 1.35E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 PIRSF PIRSF005639 1 198 3.9E-71 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 193 36.393 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 5 192 2.0E-68 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS09625 dfb479435c7a83b4f53df61c2bb3639c 198 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 Gene3D G3DSA:3.40.50.720 1 296 4.8E-53 T 29-03-2018 MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 SUPERFAMILY SSF51735 13 244 2.88E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 Pfam PF00106 short chain dehydrogenase 16 201 8.0E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12130 9786370d0c8d89ace82af8cd83bac757 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 Gene3D G3DSA:1.10.260.40 51 83 0.056 T 29-03-2018 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 SUPERFAMILY SSF46689 11 77 6.67E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 3.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 SUPERFAMILY SSF48498 91 201 1.25E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 Gene3D G3DSA:1.10.357.10 84 202 5.4E-20 T 29-03-2018 MSG_RS11645 bc5d0503ea3b2faee41bf372af053b61 208 Gene3D G3DSA:1.10.10.60 1 50 1.1E-18 T 29-03-2018 MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 Pfam PF00106 short chain dehydrogenase 11 203 8.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 SUPERFAMILY SSF51735 9 251 3.55E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS24090 b0537d8361aa086bca8d68b7d7745c7b 254 Gene3D G3DSA:3.40.50.720 7 242 8.5E-30 T 29-03-2018 MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 SMART SM00460 184 260 3.4E-23 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 82 6.6E-25 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 SUPERFAMILY SSF54001 8 349 5.19E-68 T 29-03-2018 MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 290 1110 0.0 T 29-03-2018 IPR018667 Domain of unknown function DUF2126 MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 Pfam PF01841 Transglutaminase-like superfamily 150 258 2.7E-20 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS09855 d10851e152e1179a467509076d93bdee 1117 Gene3D G3DSA:3.90.260.10 177 283 2.7E-6 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS19240 5f64f47d6ccd37caf10aebaa8da17926 366 Gene3D G3DSA:3.40.50.720 1 326 3.9E-30 T 29-03-2018 MSG_RS19240 5f64f47d6ccd37caf10aebaa8da17926 366 SUPERFAMILY SSF51735 1 288 5.36E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19240 5f64f47d6ccd37caf10aebaa8da17926 366 Pfam PF13460 NAD(P)H-binding 7 123 9.1E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11090 5dc66bf57d86c1ad49eb0827b0090df0 118 SUPERFAMILY SSF49503 34 105 4.94E-7 T 29-03-2018 IPR008972 Cupredoxin MSG_RS11090 5dc66bf57d86c1ad49eb0827b0090df0 118 Gene3D G3DSA:2.60.40.420 20 113 1.1E-5 T 29-03-2018 IPR008972 Cupredoxin MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 Pfam PF00709 Adenylosuccinate synthetase 4 422 4.7E-172 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 Gene3D G3DSA:3.40.440.10 1 152 5.8E-51 T 29-03-2018 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 Gene3D G3DSA:3.40.440.10 153 265 4.7E-22 T 29-03-2018 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 SMART SM00788 3 423 8.4E-271 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 SUPERFAMILY SSF52540 1 428 1.27E-167 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 3.7E-162 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 Gene3D G3DSA:3.90.170.10 266 430 6.6E-69 T 29-03-2018 MSG_RS02865 3a854f20206585461a25c0b197bfbc93 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 199.907 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 4.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 Gene3D G3DSA:1.10.10.10 5 82 2.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 SUPERFAMILY SSF53850 90 286 5.16E-40 T 29-03-2018 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 SUPERFAMILY SSF46785 7 87 2.59E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 Gene3D G3DSA:3.40.190.10 83 180 1.4E-24 T 29-03-2018 MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 Pfam PF03466 LysR substrate binding domain 91 284 1.9E-45 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS00535 4208dafdb51c5a8fb9589f6c5ca4767f 290 Gene3D G3DSA:3.40.190.10 181 261 1.2E-22 T 29-03-2018 MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 Pfam PF00288 GHMP kinases N terminal domain 91 148 4.4E-9 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 292 31.644 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 274 2.1E-53 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 Gene3D G3DSA:3.30.230.10 6 163 6.3E-48 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 Gene3D G3DSA:3.30.70.890 164 293 5.6E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 PIRSF PIRSF010376 4 300 4.4E-82 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 Pfam PF08544 GHMP kinases C terminal 207 274 1.9E-8 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 SUPERFAMILY SSF55060 167 285 1.91E-19 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS19930 45380e2a20e8ae311fdc473d4591f812 307 SUPERFAMILY SSF54211 5 159 1.29E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS08085 eb34aee4fd0bd49a8a6a69532fdffa3b 94 Pfam PF04023 FeoA domain 17 89 6.4E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS08085 eb34aee4fd0bd49a8a6a69532fdffa3b 94 SUPERFAMILY SSF50037 20 88 8.47E-18 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal MSG_RS08085 eb34aee4fd0bd49a8a6a69532fdffa3b 94 Gene3D G3DSA:2.30.30.90 19 94 4.0E-20 T 29-03-2018 MSG_RS08085 eb34aee4fd0bd49a8a6a69532fdffa3b 94 SMART SM00899 16 90 7.8E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 PIRSF PIRSF000151 7 414 9.8E-167 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 403 4.7E-135 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 Gene3D G3DSA:3.40.605.10 8 245 8.6E-42 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 Gene3D G3DSA:3.40.605.10 246 415 4.9E-37 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 320 341 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 SUPERFAMILY SSF53720 13 413 2.09E-113 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 Pfam PF00171 Aldehyde dehydrogenase family 13 297 9.4E-15 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 Pfam PF00171 Aldehyde dehydrogenase family 315 404 2.3E-5 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS17035 d9322aae5d047d514490137dd21f4f48 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 413 41.204 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 SUPERFAMILY SSF52402 4 185 3.35E-40 T 29-03-2018 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 PIRSF PIRSF000089 1 318 1.1E-104 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 SUPERFAMILY SSF52467 191 312 1.08E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 Gene3D G3DSA:3.40.50.620 2 184 1.7E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 Gene3D G3DSA:3.40.50.1220 189 318 1.0E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 194 276 5.4E-36 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 SMART SM00893 4 193 1.9E-28 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MSG_RS07635 d0ed81b4af85fda060dbb2bd3496b0c7 318 Pfam PF01012 Electron transfer flavoprotein domain 4 172 6.0E-31 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MSG_RS00270 2220b06e80bae36cc3c314f09f69c517 382 Gene3D G3DSA:3.40.1000.10 151 293 3.6E-19 T 29-03-2018 MSG_RS00270 2220b06e80bae36cc3c314f09f69c517 382 Pfam PF10738 Probable lipoprotein LpqN 124 292 7.2E-62 T 29-03-2018 IPR019674 Lipoprotein LpqT, predicted MSG_RS16180 774b7094de44f7058f4eba97f0a8ef72 180 Gene3D G3DSA:3.40.630.30 7 177 2.0E-34 T 29-03-2018 MSG_RS16180 774b7094de44f7058f4eba97f0a8ef72 180 Pfam PF13420 Acetyltransferase (GNAT) domain 8 161 7.1E-27 T 29-03-2018 MSG_RS16180 774b7094de44f7058f4eba97f0a8ef72 180 SUPERFAMILY SSF55729 8 168 5.83E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS13525 c81c269aa441f63a87f1f53d9404cbc8 286 Pfam PF04072 Leucine carboxyl methyltransferase 29 188 3.1E-11 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS13525 c81c269aa441f63a87f1f53d9404cbc8 286 Gene3D G3DSA:3.40.50.150 8 214 7.7E-26 T 29-03-2018 MSG_RS13525 c81c269aa441f63a87f1f53d9404cbc8 286 PIRSF PIRSF028177 14 256 1.5E-61 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MSG_RS13525 c81c269aa441f63a87f1f53d9404cbc8 286 SUPERFAMILY SSF53335 25 273 2.05E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS16850 a8cc04061be15d994a75acf4cb9ffaed 390 SMART SM00729 20 243 1.6E-56 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS16850 a8cc04061be15d994a75acf4cb9ffaed 390 Pfam PF04055 Radical SAM superfamily 25 197 3.1E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS16850 a8cc04061be15d994a75acf4cb9ffaed 390 SUPERFAMILY SSF102114 14 388 9.03E-111 T 29-03-2018 MSG_RS16850 a8cc04061be15d994a75acf4cb9ffaed 390 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 23 351 1.6E-80 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 MSG_RS16850 a8cc04061be15d994a75acf4cb9ffaed 390 Gene3D G3DSA:3.20.20.70 14 317 3.1E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS00515 adae295474b3d952ffdad79725180a98 659 SUPERFAMILY SSF51445 142 555 2.01E-127 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS00515 adae295474b3d952ffdad79725180a98 659 SUPERFAMILY SSF51445 582 651 2.01E-127 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS00515 adae295474b3d952ffdad79725180a98 659 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 141 655 2.7E-84 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS00515 adae295474b3d952ffdad79725180a98 659 Pfam PF02446 4-alpha-glucanotransferase 147 638 9.1E-112 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS00515 adae295474b3d952ffdad79725180a98 659 Gene3D G3DSA:3.20.20.80 139 658 6.7E-151 T 29-03-2018 MSG_RS19185 5f58a3411a2c3c84acd8403683f93f89 276 SUPERFAMILY SSF53335 15 231 3.57E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19185 5f58a3411a2c3c84acd8403683f93f89 276 Pfam PF04072 Leucine carboxyl methyltransferase 19 178 2.0E-12 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS19185 5f58a3411a2c3c84acd8403683f93f89 276 Gene3D G3DSA:3.40.50.150 3 227 5.6E-27 T 29-03-2018 MSG_RS19185 5f58a3411a2c3c84acd8403683f93f89 276 PIRSF PIRSF028177 5 276 1.1E-65 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 163 190 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 1.8E-127 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 PIRSF PIRSF001553 1 300 1.4E-116 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 SMART SM00881 4 109 1.7E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 PRINTS PR01798 Succinyl-CoA synthase signature 91 108 9.6E-35 T 29-03-2018 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 9.6E-35 T 29-03-2018 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 9.6E-35 T 29-03-2018 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 9.6E-35 T 29-03-2018 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 SUPERFAMILY SSF51735 1 133 1.63E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 Gene3D G3DSA:3.40.50.720 1 130 1.8E-37 T 29-03-2018 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 Pfam PF02629 CoA binding domain 6 108 2.8E-24 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 Gene3D G3DSA:3.40.50.261 131 300 3.1E-48 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 Pfam PF00549 CoA-ligase 163 280 7.0E-15 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 SUPERFAMILY SSF52210 134 295 6.41E-46 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS20345 844794b4c523f193f4db84fec8f076ad 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 297 38.98 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS13455 3694f5862cc5a97214de76de6175cafa 164 SUPERFAMILY SSF52833 1 161 2.99E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS13455 3694f5862cc5a97214de76de6175cafa 164 Pfam PF08534 Redoxin 20 160 2.1E-25 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MSG_RS13455 3694f5862cc5a97214de76de6175cafa 164 Gene3D G3DSA:3.40.30.10 3 164 1.8E-22 T 29-03-2018 MSG_RS13455 3694f5862cc5a97214de76de6175cafa 164 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 164 38.082 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 MSG_RS13455 3694f5862cc5a97214de76de6175cafa 164 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 MSG_RS16200 ce868bf0790834c11695df6021dce396 369 Gene3D G3DSA:3.40.47.10 196 357 2.8E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16200 ce868bf0790834c11695df6021dce396 369 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 263 356 3.3E-15 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS16200 ce868bf0790834c11695df6021dce396 369 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 132 207 1.1E-12 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MSG_RS16200 ce868bf0790834c11695df6021dce396 369 Gene3D G3DSA:3.40.47.10 13 195 8.2E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16200 ce868bf0790834c11695df6021dce396 369 SUPERFAMILY SSF53901 20 356 1.24E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 PRINTS PR01035 Tetracycline resistance protein signature 1 15 6.9E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 PRINTS PR01035 Tetracycline resistance protein signature 116 138 6.9E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 PRINTS PR01035 Tetracycline resistance protein signature 27 46 6.9E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 PRINTS PR01035 Tetracycline resistance protein signature 255 276 6.9E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 Gene3D G3DSA:1.20.1250.20 177 377 6.2E-31 T 29-03-2018 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 Gene3D G3DSA:1.20.1250.20 1 173 1.3E-28 T 29-03-2018 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 246 262 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 SUPERFAMILY SSF103473 2 378 2.49E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS07085 d5707a60f8d00b94c8d4639c8e6da33e 393 Pfam PF07690 Major Facilitator Superfamily 2 222 1.4E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 Pfam PF00571 CBS domain 71 123 1.1E-8 T 29-03-2018 IPR000644 CBS domain MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 Pfam PF00571 CBS domain 14 59 2.8E-8 T 29-03-2018 IPR000644 CBS domain MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 SMART SM00116 78 125 1.0E-5 T 29-03-2018 IPR000644 CBS domain MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 SMART SM00116 13 60 2.4E-5 T 29-03-2018 IPR000644 CBS domain MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 SUPERFAMILY SSF54631 1 140 2.4E-29 T 29-03-2018 MSG_RS16925 f069a5885e7bd62ff89114ab246c2d3b 142 Gene3D G3DSA:3.10.580.10 1 135 8.9E-25 T 29-03-2018 MSG_RS18985 50edb001ffe07dd4aa535c844281d356 323 Pfam PF01619 Proline dehydrogenase 52 313 1.3E-31 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MSG_RS18985 50edb001ffe07dd4aa535c844281d356 323 Gene3D G3DSA:3.20.20.220 5 323 4.7E-77 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MSG_RS18985 50edb001ffe07dd4aa535c844281d356 323 SUPERFAMILY SSF51730 44 319 2.71E-75 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MSG_RS18985 50edb001ffe07dd4aa535c844281d356 323 PIRSF PIRSF000196 8 323 1.3E-107 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 MSG_RS14175 a56f0ee5193e2ca795cede3eb89e9d9a 448 Pfam PF13520 Amino acid permease 6 406 1.3E-47 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS14175 a56f0ee5193e2ca795cede3eb89e9d9a 448 PIRSF PIRSF006060 1 441 3.4E-59 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 Gene3D G3DSA:2.40.50.140 7 123 5.1E-4 T 29-03-2018 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 10 414 24.862 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 Gene3D G3DSA:3.90.226.10 174 247 1.3E-5 T 29-03-2018 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 Pfam PF02601 Exonuclease VII, large subunit 134 350 3.2E-62 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 Pfam PF13742 OB-fold nucleic acid binding domain 18 110 1.8E-13 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MSG_RS19515 35b34da8797307a9fc460b599d4de2fb 420 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 411 3.9E-110 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 Gene3D G3DSA:3.40.50.720 6 246 1.3E-71 T 29-03-2018 MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.2E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 SUPERFAMILY SSF51735 5 237 1.27E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01575 3cd8b5df511b585e824f66fc7ad67725 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 237 4.4E-64 T 29-03-2018 MSG_RS03685 3a3e4ea597cac7b863a5616447a2383c 193 Gene3D G3DSA:3.40.30.10 23 193 1.1E-22 T 29-03-2018 MSG_RS03685 3a3e4ea597cac7b863a5616447a2383c 193 SUPERFAMILY SSF52833 54 191 4.69E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS03685 3a3e4ea597cac7b863a5616447a2383c 193 ProSitePatterns PS00194 Thioredoxin family active site. 78 96 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS03685 3a3e4ea597cac7b863a5616447a2383c 193 Pfam PF00578 AhpC/TSA family 65 171 1.4E-14 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Gene3D G3DSA:1.10.1060.10 47 77 4.8E-8 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 SUPERFAMILY SSF51971 366 413 1.18E-50 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 SUPERFAMILY SSF51971 112 319 1.18E-50 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Pfam PF00037 4Fe-4S binding domain 40 61 4.6E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 PIRSF PIRSF000362 107 547 3.5E-131 T 29-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 PRINTS PR00419 Adrenodoxin reductase family signature 114 136 3.1E-21 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 PRINTS PR00419 Adrenodoxin reductase family signature 181 191 3.1E-21 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 PRINTS PR00419 Adrenodoxin reductase family signature 253 267 3.1E-21 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 PRINTS PR00419 Adrenodoxin reductase family signature 138 151 3.1E-21 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 SUPERFAMILY SSF54862 1 82 5.8E-18 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 115 288 7.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Gene3D G3DSA:3.50.50.60 78 194 6.6E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Gene3D G3DSA:3.30.70.20 1 46 2.7E-14 T 29-03-2018 MSG_RS20715 74d78754bd5e4336c61ec4ab6ad91b7e 561 Gene3D G3DSA:3.50.50.60 196 413 4.4E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 SMART SM00738 61 169 3.4E-48 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 ProSitePatterns PS01014 Transcription termination factor nusG signature. 236 245 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 Pfam PF02357 Transcription termination factor nusG 63 165 1.5E-24 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 SUPERFAMILY SSF82679 63 165 1.44E-35 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 64 253 1.1E-66 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 Gene3D G3DSA:3.30.70.940 62 167 5.0E-36 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 SUPERFAMILY SSF50104 197 253 1.4E-16 T 29-03-2018 IPR008991 Translation protein SH3-like domain MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 Gene3D G3DSA:2.30.30.30 196 253 9.2E-18 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 PRINTS PR00338 Transcription termination factor NUSG signature 211 226 5.2E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 PRINTS PR00338 Transcription termination factor NUSG signature 229 245 5.2E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 PRINTS PR00338 Transcription termination factor NUSG signature 116 128 5.2E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MSG_RS04105 1aeea2bd3632252229c41908339609dc 253 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 61 253 23.372 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MSG_RS08345 8380468efbdfe66c5afc8687fb8ac18e 246 Gene3D G3DSA:3.40.50.2300 2 113 0.0013 T 29-03-2018 MSG_RS08345 8380468efbdfe66c5afc8687fb8ac18e 246 SUPERFAMILY SSF46894 114 213 1.96E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS08345 8380468efbdfe66c5afc8687fb8ac18e 246 Gene3D G3DSA:1.10.10.10 114 220 6.3E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08345 8380468efbdfe66c5afc8687fb8ac18e 246 SMART SM00862 140 214 2.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS08345 8380468efbdfe66c5afc8687fb8ac18e 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 140 213 3.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 SUPERFAMILY SSF50494 66 244 4.76E-22 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 Pfam PF13365 Trypsin-like peptidase domain 76 223 1.0E-9 T 29-03-2018 MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 Gene3D G3DSA:2.40.10.10 25 82 7.5E-6 T 29-03-2018 MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 Gene3D G3DSA:2.40.10.10 172 259 4.3E-11 T 29-03-2018 MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 90 95 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 MSG_RS08980 1ff2cb0139ab11bd4a96f602f5675635 272 Gene3D G3DSA:2.40.10.10 83 171 3.3E-8 T 29-03-2018 MSG_RS03890 3819b306d3320c5076bb5a7cbf952b1c 287 Hamap MF_00188 Protease HtpX [htpX]. 9 284 28.19 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MSG_RS03890 3819b306d3320c5076bb5a7cbf952b1c 287 Gene3D G3DSA:3.30.2010.10 60 153 2.3E-21 T 29-03-2018 MSG_RS03890 3819b306d3320c5076bb5a7cbf952b1c 287 Pfam PF01435 Peptidase family M48 69 284 4.5E-37 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MSG_RS13590 db12831b84623ed12250171761c79bd2 252 Pfam PF08241 Methyltransferase domain 19 121 1.1E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS13590 db12831b84623ed12250171761c79bd2 252 Gene3D G3DSA:3.40.50.150 2 171 4.4E-32 T 29-03-2018 MSG_RS13590 db12831b84623ed12250171761c79bd2 252 SUPERFAMILY SSF53335 7 197 4.11E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07570 2650931b977fd3ba5faec70246ef53a7 507 Pfam PF01593 Flavin containing amine oxidoreductase 34 473 7.0E-35 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS07570 2650931b977fd3ba5faec70246ef53a7 507 Gene3D G3DSA:3.50.50.60 20 504 1.9E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07570 2650931b977fd3ba5faec70246ef53a7 507 SUPERFAMILY SSF51905 23 342 3.11E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07570 2650931b977fd3ba5faec70246ef53a7 507 SUPERFAMILY SSF51905 432 474 3.11E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20420 2161e1835f4b2831f2fbf99327ec9b23 263 Gene3D G3DSA:3.30.750.24 16 136 2.9E-12 T 29-03-2018 IPR002645 STAS domain MSG_RS20420 2161e1835f4b2831f2fbf99327ec9b23 263 Gene3D G3DSA:3.30.565.10 137 259 6.5E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20420 2161e1835f4b2831f2fbf99327ec9b23 263 SUPERFAMILY SSF52091 22 131 5.1E-12 T 29-03-2018 IPR002645 STAS domain MSG_RS20420 2161e1835f4b2831f2fbf99327ec9b23 263 Pfam PF01740 STAS domain 22 126 1.3E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 150 2.4E-35 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 150 3.6E-23 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 151 24.374 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 5.5E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 Gene3D G3DSA:3.10.430.100 63 150 5.0E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 Gene3D G3DSA:3.40.5.10 1 49 2.6E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 SUPERFAMILY SSF55653 61 150 4.58E-21 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MSG_RS00390 cb02fb33aaba17195d4cb770ab60761f 152 SUPERFAMILY SSF55658 1 57 1.2E-16 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MSG_RS16785 75956e2fe88d946113083717756371d6 432 SMART SM00825 Beta-ketoacyl synthase 7 431 6.2E-144 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS16785 75956e2fe88d946113083717756371d6 432 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 378 1.3E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS16785 75956e2fe88d946113083717756371d6 432 Gene3D G3DSA:3.40.47.10 1 266 2.2E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16785 75956e2fe88d946113083717756371d6 432 SUPERFAMILY SSF53901 406 420 1.27E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16785 75956e2fe88d946113083717756371d6 432 SUPERFAMILY SSF53901 2 374 1.27E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16785 75956e2fe88d946113083717756371d6 432 Gene3D G3DSA:3.40.47.10 269 428 6.8E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16785 75956e2fe88d946113083717756371d6 432 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 254 3.4E-77 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS00835 49a668e6a70faaa472a219e3f65dda38 449 SUPERFAMILY SSF51556 8 36 1.66E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS00835 49a668e6a70faaa472a219e3f65dda38 449 SUPERFAMILY SSF51556 67 383 1.66E-71 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS00835 49a668e6a70faaa472a219e3f65dda38 449 Gene3D G3DSA:3.20.20.140 1 379 4.8E-61 T 29-03-2018 MSG_RS00835 49a668e6a70faaa472a219e3f65dda38 449 Pfam PF04909 Amidohydrolase 50 375 3.7E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 Pfam PF00190 Cupin 231 367 1.1E-24 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 Pfam PF00190 Cupin 59 186 6.6E-18 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 Gene3D G3DSA:2.60.120.10 2 208 2.6E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 Gene3D G3DSA:2.60.120.10 216 381 1.5E-39 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 15 380 3.6E-158 T 29-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 SUPERFAMILY SSF51182 36 377 9.17E-90 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 SMART SM00835 48 189 3.2E-16 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 MSG_RS15035 17422fe4ac4459c069cf4f3fb0938bf7 381 SMART SM00835 229 370 2.8E-37 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 MSG_RS22275 a339826d09e0b8166e115cd5ebfa0f6c 350 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 297 1.3E-76 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22275 a339826d09e0b8166e115cd5ebfa0f6c 350 Gene3D G3DSA:3.90.20.10 143 301 1.7E-4 T 29-03-2018 MSG_RS22275 a339826d09e0b8166e115cd5ebfa0f6c 350 Pfam PF02470 MlaD protein 43 118 1.1E-15 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 SMART SM00480 29 378 2.6E-139 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Gene3D G3DSA:3.10.150.10 1 133 1.2E-33 T 29-03-2018 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 PIRSF PIRSF000804 13 398 1.4E-90 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 SUPERFAMILY SSF55979 14 130 4.32E-23 T 29-03-2018 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 13 130 1.4E-37 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Gene3D G3DSA:3.10.150.10 265 397 2.8E-34 T 29-03-2018 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 SUPERFAMILY SSF55979 262 397 1.65E-26 T 29-03-2018 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 374 3.5E-34 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 13 397 2.8E-114 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 SUPERFAMILY SSF55979 139 263 6.44E-18 T 29-03-2018 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Pfam PF02767 DNA polymerase III beta subunit, central domain 139 260 5.8E-34 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS00010 863821ad76cf3c940c9c2df141e6e6af 399 Gene3D G3DSA:3.10.150.10 134 264 2.3E-30 T 29-03-2018 MSG_RS00455 267673b4d622bc4f7891fb799427f23c 153 Gene3D G3DSA:3.40.50.720 1 150 7.4E-16 T 29-03-2018 MSG_RS00455 267673b4d622bc4f7891fb799427f23c 153 Pfam PF13460 NAD(P)H-binding 8 79 2.2E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00455 267673b4d622bc4f7891fb799427f23c 153 SUPERFAMILY SSF51735 1 86 1.64E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03620 9d514c69090ffd623dc090cd47933781 146 Pfam PF01740 STAS domain 28 96 1.6E-9 T 29-03-2018 IPR002645 STAS domain MSG_RS03620 9d514c69090ffd623dc090cd47933781 146 Gene3D G3DSA:3.30.750.24 15 129 2.3E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS03620 9d514c69090ffd623dc090cd47933781 146 SUPERFAMILY SSF52091 29 125 3.34E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 Gene3D G3DSA:1.10.630.10 2 412 7.8E-58 T 29-03-2018 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 Pfam PF00067 Cytochrome P450 287 376 6.0E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 SUPERFAMILY SSF48264 3 402 1.83E-75 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 165 180 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 148 164 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 205 227 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 360 371 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 301 328 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 351 360 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 102 113 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 284 295 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS03945 65f8d8495ee4dde487bcfd6b1006f909 420 PRINTS PR00359 B-class P450 signature 329 344 4.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02040 368c5f5bcce56c3df0fd7d850ced5032 490 SUPERFAMILY SSF53720 9 482 7.85E-158 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS02040 368c5f5bcce56c3df0fd7d850ced5032 490 Pfam PF00171 Aldehyde dehydrogenase family 18 480 3.5E-165 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02040 368c5f5bcce56c3df0fd7d850ced5032 490 Gene3D G3DSA:3.40.605.10 4 273 1.8E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02040 368c5f5bcce56c3df0fd7d850ced5032 490 Gene3D G3DSA:3.40.309.10 274 466 1.9E-67 T 29-03-2018 MSG_RS02040 368c5f5bcce56c3df0fd7d850ced5032 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS12380 bc7b66828bce169841fadebd3c2cf9f0 272 Gene3D G3DSA:3.20.20.150 6 272 2.0E-26 T 29-03-2018 MSG_RS12380 bc7b66828bce169841fadebd3c2cf9f0 272 Pfam PF01261 Xylose isomerase-like TIM barrel 51 220 5.4E-10 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS12380 bc7b66828bce169841fadebd3c2cf9f0 272 SUPERFAMILY SSF51658 3 268 1.9E-41 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS09555 6edb3e6f896736742fe96a16d7a306fe 313 Gene3D G3DSA:3.20.20.70 1 313 3.0E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS09555 6edb3e6f896736742fe96a16d7a306fe 313 Pfam PF03060 Nitronate monooxygenase 86 302 1.8E-28 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS09555 6edb3e6f896736742fe96a16d7a306fe 313 Pfam PF03060 Nitronate monooxygenase 8 60 5.0E-7 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS09555 6edb3e6f896736742fe96a16d7a306fe 313 SUPERFAMILY SSF51412 2 308 1.68E-44 T 29-03-2018 MSG_RS14270 0e7ca479e07ddd96770de89db3f4472f 526 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 304 1.0E-83 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14270 0e7ca479e07ddd96770de89db3f4472f 526 Pfam PF02470 MlaD protein 40 114 1.0E-10 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS01750 df0599806b29205064abc629cb3ecad9 516 Pfam PF02470 MlaD protein 40 112 5.6E-16 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS01750 df0599806b29205064abc629cb3ecad9 516 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 293 3.6E-81 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01750 df0599806b29205064abc629cb3ecad9 516 Gene3D G3DSA:1.20.120.570 152 288 7.3E-4 T 29-03-2018 MSG_RS09435 f683a636b959a9adefcb36364f2b58af 459 Gene3D G3DSA:1.10.287.1060 9 94 0.2 T 29-03-2018 MSG_RS09435 f683a636b959a9adefcb36364f2b58af 459 Gene3D G3DSA:1.10.287.1060 128 222 0.19 T 29-03-2018 MSG_RS09435 f683a636b959a9adefcb36364f2b58af 459 SUPERFAMILY SSF140459 136 285 5.75E-7 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 Gene3D G3DSA:3.50.50.60 15 142 5.4E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 2.9E-9 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 2.9E-9 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.9E-9 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 SUPERFAMILY SSF51905 12 350 4.57E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 Gene3D G3DSA:3.50.50.60 143 350 1.8E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 5.6E-10 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 5.6E-10 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 5.6E-10 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 5.6E-10 T 29-03-2018 MSG_RS12975 7e234b50d65758dd9de6f84475e4a4c4 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 339 4.6E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 32 607 3.5E-196 T 29-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 367 502 3.4E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 490 509 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 473 490 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 452 464 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 418 437 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 404 418 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 556 568 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 366 381 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 PRINTS PR00819 CbxX/CfqX superfamily signature 326 340 3.2E-45 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 Gene3D G3DSA:1.25.40.120 7 144 9.6E-6 T 29-03-2018 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 SUPERFAMILY SSF48452 10 48 5.18E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 SUPERFAMILY SSF48452 220 260 5.18E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 SUPERFAMILY SSF48452 105 123 5.18E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 SUPERFAMILY SSF52540 325 592 8.8E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 Gene3D G3DSA:1.25.40.10 174 262 0.09 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 SMART SM00382 363 505 1.6E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS24585 cd424c34cef9b4879ef2522290a9a5d4 616 Gene3D G3DSA:3.40.50.300 298 501 1.8E-22 T 29-03-2018 MSG_RS10595 88fe49a56029c4502a2dda4ad7e0bafb 115 SUPERFAMILY SSF117916 15 109 9.81E-25 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS10595 88fe49a56029c4502a2dda4ad7e0bafb 115 Gene3D G3DSA:3.30.300.130 10 110 8.7E-22 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS10595 88fe49a56029c4502a2dda4ad7e0bafb 115 Pfam PF01883 Iron-sulfur cluster assembly protein 15 82 4.5E-17 T 29-03-2018 IPR002744 MIP18 family-like MSG_RS01275 89cf08c23eb3db0c068c06acca882847 152 Pfam PF12802 MarR family 38 94 5.9E-10 T 29-03-2018 MSG_RS01275 89cf08c23eb3db0c068c06acca882847 152 Gene3D G3DSA:1.10.10.10 2 152 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01275 89cf08c23eb3db0c068c06acca882847 152 SMART SM00347 30 130 1.1E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS01275 89cf08c23eb3db0c068c06acca882847 152 SUPERFAMILY SSF46785 11 145 7.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24640 5e654689252c4d277f8ce819a531c767 805 Gene3D G3DSA:2.60.40.10 54 177 3.0E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS19175 9cf7be4c24b10f4f165c2dc7e097e0b4 147 SUPERFAMILY SSF50475 6 143 1.25E-36 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS19175 9cf7be4c24b10f4f165c2dc7e097e0b4 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 1.3E-16 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS19175 9cf7be4c24b10f4f165c2dc7e097e0b4 147 Gene3D G3DSA:2.30.110.10 1 143 2.8E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS19175 9cf7be4c24b10f4f165c2dc7e097e0b4 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 141 1.1E-40 T 29-03-2018 IPR019920 F420-binding domain, putative MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Pfam PF04851 Type III restriction enzyme, res subunit 39 161 5.6E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SUPERFAMILY SSF52540 28 437 1.62E-130 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SMART SM00487 32 447 6.6E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Pfam PF00271 Helicase conserved C-terminal domain 458 566 1.1E-16 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Hamap MF_00204 UvrABC system protein B [uvrB]. 26 709 43.21 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Gene3D G3DSA:3.40.50.300 438 611 3.7E-31 T 29-03-2018 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Gene3D G3DSA:3.40.50.300 34 437 2.3E-32 T 29-03-2018 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SMART SM00490 482 568 3.2E-16 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SUPERFAMILY SSF46600 666 711 4.05E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SUPERFAMILY SSF52540 481 602 8.88E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 SUPERFAMILY SSF52540 56 105 8.88E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Pfam PF02151 UvrB/uvrC motif 676 709 1.7E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Pfam PF12344 Ultra-violet resistance protein B 574 615 2.1E-22 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 Gene3D G3DSA:4.10.860.10 657 712 5.1E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 MSG_RS11375 322f4881f1a951aa13ec45d6992027b1 719 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 27 707 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MSG_RS16330 7d41384f0f137cb7f2061a7d2004b5da 308 SUPERFAMILY SSF56059 121 287 4.38E-21 T 29-03-2018 MSG_RS16330 7d41384f0f137cb7f2061a7d2004b5da 308 Gene3D G3DSA:3.30.470.20 174 304 1.1E-10 T 29-03-2018 MSG_RS16330 7d41384f0f137cb7f2061a7d2004b5da 308 Gene3D G3DSA:3.30.1490.20 106 173 1.5E-5 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS16330 7d41384f0f137cb7f2061a7d2004b5da 308 Pfam PF02655 ATP-grasp domain 119 285 1.6E-7 T 29-03-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 MSG_RS15875 2be1f9b9d636b0375394daadb8768775 253 Gene3D G3DSA:3.40.630.40 24 253 4.0E-39 T 29-03-2018 MSG_RS15875 2be1f9b9d636b0375394daadb8768775 253 SMART SM00646 124 245 5.4E-23 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS15875 2be1f9b9d636b0375394daadb8768775 253 SUPERFAMILY SSF53187 42 249 1.17E-30 T 29-03-2018 MSG_RS15875 2be1f9b9d636b0375394daadb8768775 253 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 43 245 4.3E-30 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS07245 669b4c024dded37b1116e003fb02e5ca 756 Pfam PF02554 Carbon starvation protein CstA 60 437 3.1E-162 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MSG_RS07245 669b4c024dded37b1116e003fb02e5ca 756 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 496 626 1.1E-32 T 29-03-2018 IPR025299 CstA, C-terminal domain MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 SUPERFAMILY SSF55103 218 457 1.96E-52 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 454 1.1E-55 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 Gene3D G3DSA:3.30.465.10 93 236 2.8E-36 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 SUPERFAMILY SSF56176 2 213 6.54E-63 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 Gene3D G3DSA:3.30.43.10 1 92 7.5E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 Pfam PF01565 FAD binding domain 40 178 1.1E-38 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS15950 6175a9aad98b212953f0bffc1b726f9d 459 Gene3D G3DSA:1.10.45.10 416 455 8.3E-13 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SMART SM00388 239 311 1.3E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SUPERFAMILY SSF55874 301 464 3.8E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SUPERFAMILY SSF158472 189 235 9.42E-7 T 29-03-2018 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 Gene3D G3DSA:3.30.565.10 313 466 1.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 311 4.5E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SMART SM00304 186 238 7.0E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SUPERFAMILY SSF47384 222 311 1.69E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 1.6E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 463 6.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 Gene3D G3DSA:1.10.287.130 229 307 7.9E-12 T 29-03-2018 MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 SMART SM00387 351 466 7.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20235 ac7dc9e9274a6299c85ab8423696e82d 509 Pfam PF00672 HAMP domain 186 234 3.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS24715 f9474de9ee816863c24b41436d22f322 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 1.9E-16 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS24715 f9474de9ee816863c24b41436d22f322 47 Pfam PF00468 Ribosomal protein L34 5 47 1.3E-17 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS24715 f9474de9ee816863c24b41436d22f322 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 45 2.0E-14 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS24715 f9474de9ee816863c24b41436d22f322 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.077 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS24715 f9474de9ee816863c24b41436d22f322 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS24490 b10305287d9bd71d0d92e78172367697 748 Gene3D G3DSA:3.40.50.300 369 724 2.5E-19 T 29-03-2018 MSG_RS24490 b10305287d9bd71d0d92e78172367697 748 Pfam PF01580 FtsK/SpoIIIE family 434 639 2.6E-45 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS24490 b10305287d9bd71d0d92e78172367697 748 SUPERFAMILY SSF52540 434 693 3.06E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24490 b10305287d9bd71d0d92e78172367697 748 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 706 3.0E-230 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS11830 ee5452aaf3b7e462eb1497da71bcca1b 126 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2 112 3.3E-26 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MSG_RS11830 ee5452aaf3b7e462eb1497da71bcca1b 126 PIRSF PIRSF004761 1 115 5.8E-20 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MSG_RS11830 ee5452aaf3b7e462eb1497da71bcca1b 126 Gene3D G3DSA:3.30.40.10 15 96 0.0011 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 2 282 1.7E-74 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 Pfam PF02470 MlaD protein 29 102 1.7E-15 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 Gene3D G3DSA:1.20.1170.10 101 286 2.3E-5 T 29-03-2018 MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 131 290 1.5E-9 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 166 184 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 81 97 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 235 254 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 18 38 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 286 305 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16540 5e4c206181c190e974985e5edd9be3cc 377 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 117 141 4.5E-28 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Pfam PF01842 ACT domain 456 515 2.4E-7 T 29-03-2018 IPR002912 ACT domain MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 6 527 3.9E-203 T 29-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 2.1E-62 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 SUPERFAMILY SSF55021 453 522 4.16E-12 T 29-03-2018 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Gene3D G3DSA:3.40.50.720 1 107 2.9E-34 T 29-03-2018 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Gene3D G3DSA:3.30.70.260 450 525 2.2E-11 T 29-03-2018 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 SUPERFAMILY SSF52283 4 134 3.97E-38 T 29-03-2018 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Gene3D G3DSA:3.40.50.720 108 283 3.7E-58 T 29-03-2018 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 SUPERFAMILY SSF51735 101 281 1.74E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 313 4.9E-38 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 SUPERFAMILY SSF143548 320 449 2.14E-33 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MSG_RS07785 c55ff41531b1f5e7505c2453a89853c2 528 Gene3D G3DSA:3.30.1330.90 315 449 4.5E-32 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 8 279 1.3E-117 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 276 6.9E-47 T 29-03-2018 MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 Gene3D G3DSA:3.40.50.720 4 276 8.4E-63 T 29-03-2018 MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 3.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 98 109 3.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 3.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 SUPERFAMILY SSF51735 6 279 4.34E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05980 c743d2a1ca0a573e13108f28806c72e6 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 Pfam PF00067 Cytochrome P450 271 426 5.1E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 Gene3D G3DSA:1.10.630.10 40 465 7.8E-66 T 29-03-2018 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 401 410 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 378 393 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 333 344 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 350 377 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 191 207 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 145 156 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 208 223 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 399 408 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 PRINTS PR00359 B-class P450 signature 408 419 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS02730 eb21c9c18832f96b46f0a88479ddd8e1 469 SUPERFAMILY SSF48264 75 459 4.98E-81 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07640 2f2d60487c5df1260c963088a7bdf559 281 Gene3D G3DSA:3.40.630.30 27 167 2.3E-31 T 29-03-2018 MSG_RS07640 2f2d60487c5df1260c963088a7bdf559 281 SUPERFAMILY SSF55729 24 243 4.58E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS07640 2f2d60487c5df1260c963088a7bdf559 281 Pfam PF13444 Acetyltransferase (GNAT) domain 42 143 1.4E-28 T 29-03-2018 MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 Gene3D G3DSA:2.40.100.10 100 220 1.7E-50 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 SUPERFAMILY SSF160467 21 70 1.31E-8 T 29-03-2018 MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 19 209 1.2E-64 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 Gene3D G3DSA:3.30.1360.40 18 99 5.9E-18 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 SMART SM00796 17 209 2.0E-86 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MSG_RS02275 54804c606bc1d51a5c32b3eb8369de0a 220 SUPERFAMILY SSF50891 99 219 6.07E-40 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS21225 f872efd91c8e3744154c924c73008ae6 98 Gene3D G3DSA:3.30.70.20 1 65 0.0013 T 29-03-2018 MSG_RS21225 f872efd91c8e3744154c924c73008ae6 98 SUPERFAMILY SSF54862 2 61 3.56E-9 T 29-03-2018 MSG_RS21225 f872efd91c8e3744154c924c73008ae6 98 Pfam PF13459 4Fe-4S single cluster domain 3 61 1.4E-13 T 29-03-2018 MSG_RS16450 1928d516716f4e187f1feab9cbed2b71 265 Pfam PF02361 Cobalt transport protein 9 227 2.6E-40 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component MSG_RS00675 59b357fbf6a08c0120203753b939f2a5 389 PIRSF PIRSF000337 307 389 2.8E-17 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00675 59b357fbf6a08c0120203753b939f2a5 389 PIRSF PIRSF000337 4 312 7.2E-63 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00675 59b357fbf6a08c0120203753b939f2a5 389 Pfam PF00296 Luciferase-like monooxygenase 22 299 9.1E-34 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00675 59b357fbf6a08c0120203753b939f2a5 389 SUPERFAMILY SSF51679 6 382 1.1E-80 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00675 59b357fbf6a08c0120203753b939f2a5 389 Gene3D G3DSA:3.20.20.30 1 389 2.8E-76 T 29-03-2018 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 SUPERFAMILY SSF55681 101 339 8.67E-73 T 29-03-2018 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 Gene3D G3DSA:3.30.930.10 16 345 1.2E-73 T 29-03-2018 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 17 343 44.635 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 Pfam PF01409 tRNA synthetases class II core domain (F) 101 340 1.9E-98 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 59 339 1.2E-83 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 29 96 7.3E-16 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MSG_RS11485 5e8983b3fa5749735d6ee138542dd6fb 347 SUPERFAMILY SSF46589 23 107 4.87E-15 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MSG_RS12370 418f25e82c826557b9e1537e804b8740 544 SUPERFAMILY SSF53649 2 521 2.47E-146 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS12370 418f25e82c826557b9e1537e804b8740 544 ProSitePatterns PS00149 Sulfatases signature 2. 105 115 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS12370 418f25e82c826557b9e1537e804b8740 544 Gene3D G3DSA:3.40.720.10 1 445 5.8E-111 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS12370 418f25e82c826557b9e1537e804b8740 544 Pfam PF00884 Sulfatase 4 415 6.7E-79 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS12370 418f25e82c826557b9e1537e804b8740 544 Gene3D G3DSA:3.30.1120.10 446 524 1.8E-18 T 29-03-2018 MSG_RS16295 9c7452177fdd219e71d2bd8b34529a2d 129 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 124 28.308 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 MSG_RS16295 9c7452177fdd219e71d2bd8b34529a2d 129 Gene3D G3DSA:3.10.450.50 3 126 5.9E-45 T 29-03-2018 MSG_RS16295 9c7452177fdd219e71d2bd8b34529a2d 129 Pfam PF02810 SEC-C motif 4 19 3.3E-4 T 29-03-2018 IPR004027 SEC-C motif MSG_RS16295 9c7452177fdd219e71d2bd8b34529a2d 129 SUPERFAMILY SSF54427 25 123 5.95E-34 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 Pfam PF07969 Amidohydrolase family 36 431 8.5E-27 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 Gene3D G3DSA:3.20.20.140 59 386 5.6E-31 T 29-03-2018 MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 Gene3D G3DSA:2.30.40.10 1 58 1.3E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 SUPERFAMILY SSF51556 47 61 1.51E-17 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 SUPERFAMILY SSF51556 156 375 1.51E-17 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 SUPERFAMILY SSF51338 14 49 2.56E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS01990 5f949f1d2c678c91d1f2c5da03b6c130 434 SUPERFAMILY SSF51338 399 431 2.56E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS01945 442ff0c45c54317d044c9ae97e03e885 502 Gene3D G3DSA:3.40.50.300 71 485 6.3E-5 T 29-03-2018 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 20 43 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 122 140 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 287 314 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 103 120 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 319 345 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PRINTS PR00067 Catalase signature 82 100 2.9E-64 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 Pfam PF06628 Catalase-related immune-responsive 415 477 6.0E-18 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 SMART SM01060 7 388 5.1E-272 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 SUPERFAMILY SSF56634 4 480 4.84E-196 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 PIRSF PIRSF038928 1 483 7.8E-228 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 Pfam PF00199 Catalase 7 384 2.9E-182 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS23370 623bfe3dccb033534766174193f17b39 483 Gene3D G3DSA:2.40.180.10 1 356 2.0E-155 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MSG_RS04015 ca7bacc75c5e8258382609324bb07c29 315 Gene3D G3DSA:3.40.50.150 1 301 3.1E-59 T 29-03-2018 MSG_RS04015 ca7bacc75c5e8258382609324bb07c29 315 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 2.0E-62 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS04015 ca7bacc75c5e8258382609324bb07c29 315 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 292 2.2E-85 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS04015 ca7bacc75c5e8258382609324bb07c29 315 SUPERFAMILY SSF53335 15 310 2.33E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 SUPERFAMILY SSF52540 124 372 5.16E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 ProSitePatterns PS01215 Mrp family signature. 228 244 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 Hamap MF_02040 Iron-sulfur cluster carrier protein. 118 370 33.507 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 Pfam PF01883 Iron-sulfur cluster assembly protein 15 87 2.7E-18 T 29-03-2018 IPR002744 MIP18 family-like MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 Gene3D G3DSA:3.40.50.300 98 377 2.3E-56 T 29-03-2018 MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 Gene3D G3DSA:3.30.300.130 10 97 4.8E-18 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 SUPERFAMILY SSF117916 15 104 2.45E-20 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS18785 220fec4d6cac10c39f5b36f958d4c37b 388 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 124 368 3.3E-88 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 Gene3D G3DSA:1.10.10.10 77 159 6.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 Pfam PF08281 Sigma-70, region 4 116 167 9.8E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 Gene3D G3DSA:3.10.450.50 160 293 1.1E-6 T 29-03-2018 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 SUPERFAMILY SSF88659 110 168 1.13E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 Pfam PF04542 Sigma-70 region 2 15 78 9.7E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 SUPERFAMILY SSF88946 9 75 2.16E-13 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 168 8.2E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS24435 fe55d505abc3c0bcfa0c855bd804b4a7 294 Gene3D G3DSA:1.10.1740.10 3 76 1.4E-13 T 29-03-2018 MSG_RS03305 0cc981c305dc268f9584bbe636836920 304 SUPERFAMILY SSF52096 5 263 1.51E-55 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS03305 0cc981c305dc268f9584bbe636836920 304 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 118 138 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS03305 0cc981c305dc268f9584bbe636836920 304 Gene3D G3DSA:3.90.226.10 1 277 1.8E-52 T 29-03-2018 MSG_RS03305 0cc981c305dc268f9584bbe636836920 304 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 235 1.0E-28 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS20050 cd731ac046405f133d5ff40458834bf4 545 Gene3D G3DSA:3.20.20.80 58 501 1.5E-7 T 29-03-2018 MSG_RS20050 cd731ac046405f133d5ff40458834bf4 545 SUPERFAMILY SSF51445 91 220 1.78E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS05800 24456e88a73a65e3f37c2194df0d020b 307 Gene3D G3DSA:3.90.25.10 208 276 6.3E-18 T 29-03-2018 MSG_RS05800 24456e88a73a65e3f37c2194df0d020b 307 Gene3D G3DSA:3.40.50.720 2 207 5.7E-32 T 29-03-2018 MSG_RS05800 24456e88a73a65e3f37c2194df0d020b 307 SUPERFAMILY SSF51735 4 288 6.67E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05800 24456e88a73a65e3f37c2194df0d020b 307 Pfam PF04321 RmlD substrate binding domain 4 291 4.1E-96 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MSG_RS05800 24456e88a73a65e3f37c2194df0d020b 307 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 290 2.6E-93 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MSG_RS24700 b3744330e49a9e70c67f1ef37bc99ef6 364 Pfam PF02096 60Kd inner membrane protein 40 273 4.9E-48 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MSG_RS24700 b3744330e49a9e70c67f1ef37bc99ef6 364 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 40 273 7.9E-56 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal MSG_RS16955 d30ef8e7cf6c657af3cd3bb1ef94f863 318 Gene3D G3DSA:3.40.50.300 1 120 2.4E-9 T 29-03-2018 MSG_RS16955 d30ef8e7cf6c657af3cd3bb1ef94f863 318 Gene3D G3DSA:1.10.8.60 127 201 9.3E-12 T 29-03-2018 MSG_RS16955 d30ef8e7cf6c657af3cd3bb1ef94f863 318 Gene3D G3DSA:1.20.272.10 202 315 5.6E-22 T 29-03-2018 MSG_RS16955 d30ef8e7cf6c657af3cd3bb1ef94f863 318 SUPERFAMILY SSF52540 3 176 1.33E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16955 d30ef8e7cf6c657af3cd3bb1ef94f863 318 SUPERFAMILY SSF48019 195 310 1.7E-10 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MSG_RS17545 683e2ad0e392e9f4828544407f887311 390 Gene3D G3DSA:3.40.190.10 40 152 8.3E-10 T 29-03-2018 MSG_RS17545 683e2ad0e392e9f4828544407f887311 390 Gene3D G3DSA:3.40.190.10 153 337 1.8E-25 T 29-03-2018 MSG_RS17545 683e2ad0e392e9f4828544407f887311 390 Pfam PF13379 NMT1-like family 41 275 3.4E-40 T 29-03-2018 MSG_RS17545 683e2ad0e392e9f4828544407f887311 390 SUPERFAMILY SSF53850 44 274 2.23E-27 T 29-03-2018 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 6 445 4.9E-39 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 SUPERFAMILY SSF54373 297 399 2.16E-21 T 29-03-2018 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 SUPERFAMILY SSF51905 7 311 6.96E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 SUPERFAMILY SSF51905 413 446 6.96E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 Pfam PF01593 Flavin containing amine oxidoreductase 13 446 2.2E-25 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 Gene3D G3DSA:3.40.50.720 5 119 9.4E-12 T 29-03-2018 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 Gene3D G3DSA:3.90.660.20 198 399 9.2E-31 T 29-03-2018 MSG_RS09160 7f817171c19f411a853f112a17c23103 458 Gene3D G3DSA:1.10.3110.10 120 197 1.7E-14 T 29-03-2018 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Gene3D G3DSA:3.90.199.10 42 224 1.4E-80 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 SUPERFAMILY SSF101904 511 830 8.5E-101 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 SUPERFAMILY SSF56719 11 501 1.27E-168 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 16 819 0.0 T 29-03-2018 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 SMART SM00434 19 477 1.3E-271 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 566 609 4.6E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 516 562 1.6E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 774 817 1.1E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 670 718 4.4E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 623 667 1.2E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 723 770 8.4E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Gene3D G3DSA:1.10.268.10 357 499 8.7E-47 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 11 821 23.626 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 484 4.2E-146 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Gene3D G3DSA:2.120.10.90 511 836 1.0E-115 T 29-03-2018 MSG_RS00030 ac440a36db2a01a3838c5b7b43dd66fc 837 Gene3D G3DSA:3.30.1360.40 248 345 1.2E-32 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MSG_RS17445 b3ec6b6f54892a5630ea0dbc417d57cb 299 Pfam PF01758 Sodium Bile acid symporter family 8 190 3.7E-29 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 PRINTS PR00421 Thioredoxin family signature 21 29 1.8E-8 T 29-03-2018 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 PRINTS PR00421 Thioredoxin family signature 68 79 1.8E-8 T 29-03-2018 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 PRINTS PR00421 Thioredoxin family signature 29 38 1.8E-8 T 29-03-2018 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 SUPERFAMILY SSF52833 5 103 8.02E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 Gene3D G3DSA:3.40.30.10 1 116 1.6E-33 T 29-03-2018 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 PIRSF PIRSF000077 1 104 2.4E-28 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.3E-32 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MSG_RS10610 ffbe7c97f076faddb13ccd62a4278353 116 Pfam PF00085 Thioredoxin 5 101 1.4E-26 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 187 38.063 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 106 119 - T 29-03-2018 IPR033135 ClpP, histidine active site MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 Pfam PF00574 Clp protease 12 186 9.7E-75 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 PRINTS PR00127 Clp protease catalytic subunit P signature 13 28 1.5E-47 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 1.5E-47 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 1.5E-47 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 PRINTS PR00127 Clp protease catalytic subunit P signature 105 124 1.5E-47 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 1.5E-47 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 SUPERFAMILY SSF52096 13 186 8.39E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS17220 f8109ec868759d6e2b6480a8c5ede6bd 196 Gene3D G3DSA:3.90.226.10 15 187 1.2E-41 T 29-03-2018 MSG_RS08485 7ae47d126681423dcb04864dfcbf5038 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 23 204 1.3E-58 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MSG_RS08485 7ae47d126681423dcb04864dfcbf5038 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 18 204 4.2E-76 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MSG_RS08485 7ae47d126681423dcb04864dfcbf5038 204 SUPERFAMILY SSF52540 12 204 2.39E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08485 7ae47d126681423dcb04864dfcbf5038 204 PIRSF PIRSF015617 1 204 2.0E-64 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MSG_RS08485 7ae47d126681423dcb04864dfcbf5038 204 Gene3D G3DSA:3.40.50.300 6 204 3.9E-62 T 29-03-2018 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 Pfam PF13459 4Fe-4S single cluster domain 5 63 1.6E-15 T 29-03-2018 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 SUPERFAMILY SSF54862 4 63 2.42E-10 T 29-03-2018 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 Gene3D G3DSA:3.30.70.20 2 66 5.0E-6 T 29-03-2018 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 6.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 6.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21255 17fc86864a402ca08d4a6ac4bdd73543 66 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 6.3E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00385 P450 superfamily signature 284 295 7.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00385 P450 superfamily signature 352 361 7.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00385 P450 superfamily signature 361 372 7.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00385 P450 superfamily signature 247 264 7.7E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 330 345 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 165 180 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 202 224 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 302 329 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 101 112 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 361 372 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 148 164 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 284 295 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 PRINTS PR00359 B-class P450 signature 352 361 1.3E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 Pfam PF00067 Cytochrome P450 198 381 2.8E-19 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 SUPERFAMILY SSF48264 24 412 1.57E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21405 6eefeb857504927a834207db89e51701 412 Gene3D G3DSA:1.10.630.10 6 412 1.9E-62 T 29-03-2018 MSG_RS21405 6eefeb857504927a834207db89e51701 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 SMART SM01208 194 272 1.8E-19 T 29-03-2018 IPR011098 G5 domain MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Gene3D G3DSA:1.10.530.10 267 362 2.4E-32 T 29-03-2018 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 SUPERFAMILY SSF53955 278 360 5.91E-31 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Pfam PF03990 Domain of unknown function (DUF348) 27 67 8.6E-6 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Pfam PF03990 Domain of unknown function (DUF348) 85 114 1.1E-7 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Pfam PF03990 Domain of unknown function (DUF348) 141 180 7.4E-9 T 29-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Pfam PF06737 Transglycosylase-like domain 281 355 8.4E-34 T 29-03-2018 IPR010618 Transglycosylase-like MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Gene3D G3DSA:2.20.230.10 193 266 4.4E-14 T 29-03-2018 MSG_RS19940 896bb9f9fbab8e2a71192ae2ee40408c 362 Pfam PF07501 G5 domain 198 271 1.1E-17 T 29-03-2018 IPR011098 G5 domain MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 Gene3D G3DSA:3.40.640.10 128 333 8.3E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 Gene3D G3DSA:3.90.1150.10 334 438 6.3E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.0E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 Gene3D G3DSA:1.10.10.10 7 82 3.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 SUPERFAMILY SSF53383 71 436 8.58E-56 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 Pfam PF00155 Aminotransferase class I and II 127 431 9.7E-21 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 SUPERFAMILY SSF46785 12 83 3.71E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11025 2a7536b37b5d6ab80b5b7ff0cc3aa468 443 SMART SM00345 15 74 1.9E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Gene3D G3DSA:3.10.290.10 327 422 1.2E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 1.5E-30 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 1.5E-30 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 1.5E-30 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 1.5E-30 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 418 2.3E-111 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 SUPERFAMILY SSF52374 4 325 3.15E-95 T 29-03-2018 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Gene3D G3DSA:1.10.240.10 224 326 3.3E-29 T 29-03-2018 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Gene3D G3DSA:3.40.50.620 1 223 2.8E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 SUPERFAMILY SSF55174 343 419 5.21E-15 T 29-03-2018 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Pfam PF00579 tRNA synthetases class I (W and Y) 30 325 5.4E-83 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 SMART SM00363 355 416 4.2E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 420 43.412 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MSG_RS11670 c0c3fc133ead530101a581e88dc65361 423 Pfam PF01479 S4 domain 357 389 3.0E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 98 1.0E-28 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 Gene3D G3DSA:3.30.590.10 108 461 1.4E-124 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 265 280 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 Gene3D G3DSA:3.10.20.70 5 107 1.8E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 SMART SM01230 105 387 1.5E-148 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 SUPERFAMILY SSF54368 5 103 5.75E-34 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 394 406 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 477 5.7E-205 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 Pfam PF00120 Glutamine synthetase, catalytic domain 106 475 1.4E-134 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS07015 124665f22fb49f5c670bb72edabe920c 478 SUPERFAMILY SSF55931 106 477 1.37E-137 T 29-03-2018 MSG_RS04220 fa784335d9038f537e938d70f6689d03 405 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 144 393 4.9E-19 T 29-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 MSG_RS04220 fa784335d9038f537e938d70f6689d03 405 Gene3D G3DSA:3.30.360.10 160 341 1.8E-45 T 29-03-2018 MSG_RS04220 fa784335d9038f537e938d70f6689d03 405 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 139 1.8E-17 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MSG_RS04220 fa784335d9038f537e938d70f6689d03 405 Gene3D G3DSA:3.40.50.720 1 159 1.9E-21 T 29-03-2018 MSG_RS04220 fa784335d9038f537e938d70f6689d03 405 SUPERFAMILY SSF51735 1 167 1.46E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 1.7E-148 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 SUPERFAMILY SSF81442 27 538 1.26E-174 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 Gene3D G3DSA:1.20.210.10 26 539 3.2E-196 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 2.6E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 535 6.5E-215 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MSG_RS07455 21407e5dafb8bcae1db1e33f9b4211be 581 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SUPERFAMILY SSF63380 1032 1251 2.04E-62 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00369 Flavodoxin signature 962 981 3.3E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00369 Flavodoxin signature 858 871 3.3E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00369 Flavodoxin signature 906 917 3.3E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00369 Flavodoxin signature 938 948 3.3E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SMART SM00926 1 55 4.6E-9 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:3.40.228.10 164 253 2.1E-28 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF01568 Molydopterin dinucleotide binding domain 597 708 2.6E-36 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:3.40.50.360 835 1005 1.8E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SUPERFAMILY SSF52343 1249 1404 5.24E-52 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:2.40.30.10 1024 1247 1.7E-49 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:2.40.40.20 553 714 6.9E-48 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:2.20.25.90 1 55 3.7E-13 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SUPERFAMILY SSF53706 1 599 7.59E-180 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:3.40.50.740 58 163 1.8E-16 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:3.40.50.740 254 544 1.1E-76 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF00175 Oxidoreductase NAD-binding domain 1262 1368 1.2E-15 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 51 1.1E-10 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF00258 Flavodoxin 859 980 2.9E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1073 1083 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1330 1346 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1286 1295 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1353 1361 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1299 1310 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1192 1199 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1225 1234 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1261 1280 6.8E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF00384 Molybdopterin oxidoreductase 72 485 3.0E-70 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SUPERFAMILY SSF50692 569 714 9.95E-49 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Gene3D G3DSA:3.40.50.80 1248 1403 6.7E-35 T 29-03-2018 MSG_RS16485 fc5271f34edddae442483560c8675230 1404 SUPERFAMILY SSF52218 853 999 3.77E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS16485 fc5271f34edddae442483560c8675230 1404 Pfam PF00667 FAD binding domain 1035 1230 4.9E-29 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Pfam PF07568 Histidine kinase 299 366 8.0E-22 T 29-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Gene3D G3DSA:3.30.450.20 169 287 3.7E-9 T 29-03-2018 MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 SUPERFAMILY SSF55874 354 492 1.96E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Gene3D G3DSA:3.30.565.10 288 493 1.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 491 1.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Pfam PF12282 Signal transduction histidine kinase 4 150 3.2E-43 T 29-03-2018 IPR022066 Signal transduction histidine kinase MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 SUPERFAMILY SSF55785 179 290 1.54E-6 T 29-03-2018 IPR000014 PAS domain MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 Pfam PF08448 PAS fold 177 285 2.3E-6 T 29-03-2018 IPR013656 PAS fold-4 MSG_RS06180 d2645f5f86e938b2b08bb75204fbb6fb 500 SMART SM00387 393 494 3.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SUPERFAMILY SSF141868 355 602 6.8E-80 T 29-03-2018 IPR001633 EAL domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SMART SM00065 23 176 2.4E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Gene3D G3DSA:3.30.450.40 8 177 5.3E-16 T 29-03-2018 IPR029016 GAF domain-like MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SUPERFAMILY SSF55781 27 179 4.58E-15 T 29-03-2018 IPR029016 GAF domain-like MSG_RS20055 1a747957c13c648a14a293755c339e19 620 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 337 9.5E-31 T 29-03-2018 IPR000160 GGDEF domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Gene3D G3DSA:3.20.20.450 345 606 4.2E-86 T 29-03-2018 IPR001633 EAL domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Pfam PF13185 GAF domain 22 164 1.5E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 333 2.0E-34 T 29-03-2018 IPR000160 GGDEF domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Gene3D G3DSA:3.30.70.270 178 344 3.4E-48 T 29-03-2018 MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SMART SM00052 347 594 6.5E-100 T 29-03-2018 IPR001633 EAL domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SMART SM00267 168 337 1.5E-50 T 29-03-2018 IPR000160 GGDEF domain MSG_RS20055 1a747957c13c648a14a293755c339e19 620 SUPERFAMILY SSF55073 184 337 8.63E-38 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS20055 1a747957c13c648a14a293755c339e19 620 Pfam PF00563 EAL domain 355 589 2.8E-66 T 29-03-2018 IPR001633 EAL domain MSG_RS07775 b51bf2f820114766ec451dfd83c8d60b 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 168 1.9E-42 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MSG_RS07775 b51bf2f820114766ec451dfd83c8d60b 199 SUPERFAMILY SSF52218 3 197 2.62E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS07775 b51bf2f820114766ec451dfd83c8d60b 199 Pfam PF03358 NADPH-dependent FMN reductase 3 146 3.3E-16 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MSG_RS07775 b51bf2f820114766ec451dfd83c8d60b 199 Gene3D G3DSA:3.40.50.360 2 199 2.7E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS02215 52c9ed9783623107f90ff841b0e67ad9 164 Gene3D G3DSA:1.10.10.10 3 162 6.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02215 52c9ed9783623107f90ff841b0e67ad9 164 SUPERFAMILY SSF46785 7 136 8.25E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02215 52c9ed9783623107f90ff841b0e67ad9 164 Pfam PF01638 HxlR-like helix-turn-helix 20 98 3.3E-13 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 SUPERFAMILY SSF51735 8 258 2.25E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 1.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.5E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 Gene3D G3DSA:3.40.50.720 7 302 1.5E-60 T 29-03-2018 MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 Pfam PF00106 short chain dehydrogenase 13 205 1.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.7E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 2.7E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.7E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.7E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.7E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22295 5f57feb696539539babc15efd37fa5a9 304 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 228 0.0031 T 29-03-2018 MSG_RS01495 39b720ab84cb91f870f963522d657717 346 Pfam PF02678 Pirin 45 146 5.8E-29 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MSG_RS01495 39b720ab84cb91f870f963522d657717 346 Pfam PF05726 Pirin C-terminal cupin domain 202 311 2.7E-28 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MSG_RS01495 39b720ab84cb91f870f963522d657717 346 PIRSF PIRSF006232 22 317 5.0E-82 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MSG_RS01495 39b720ab84cb91f870f963522d657717 346 SUPERFAMILY SSF51182 24 315 1.39E-76 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS01495 39b720ab84cb91f870f963522d657717 346 Gene3D G3DSA:2.60.120.10 20 284 3.5E-73 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS02310 074731573226db28fd45f3bb7b462826 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 311 1.7E-21 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MSG_RS02310 074731573226db28fd45f3bb7b462826 316 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MSG_RS02310 074731573226db28fd45f3bb7b462826 316 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MSG_RS02310 074731573226db28fd45f3bb7b462826 316 Gene3D G3DSA:3.40.50.720 3 111 1.1E-23 T 29-03-2018 MSG_RS02310 074731573226db28fd45f3bb7b462826 316 SUPERFAMILY SSF51735 100 279 2.35E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02310 074731573226db28fd45f3bb7b462826 316 Gene3D G3DSA:3.40.50.720 112 282 4.2E-47 T 29-03-2018 MSG_RS02310 074731573226db28fd45f3bb7b462826 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 278 1.0E-50 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MSG_RS02310 074731573226db28fd45f3bb7b462826 316 SUPERFAMILY SSF52283 17 131 6.99E-22 T 29-03-2018 MSG_RS01605 9dddc016567c55631b931804ccff0719 272 SUPERFAMILY SSF63829 4 245 1.31E-45 T 29-03-2018 MSG_RS01605 9dddc016567c55631b931804ccff0719 272 Gene3D G3DSA:2.120.10.30 18 272 4.9E-30 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS01605 9dddc016567c55631b931804ccff0719 272 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 243 4.3E-46 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MSG_RS01605 9dddc016567c55631b931804ccff0719 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 183 200 5.0E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS01605 9dddc016567c55631b931804ccff0719 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 225 243 5.0E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS01605 9dddc016567c55631b931804ccff0719 272 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 123 145 5.0E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS20960 e1e71ccb1b202b56233e46a8419b1dbc 392 SUPERFAMILY SSF53383 5 386 6.59E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS20960 e1e71ccb1b202b56233e46a8419b1dbc 392 Gene3D G3DSA:3.90.1150.10 292 388 1.2E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS20960 e1e71ccb1b202b56233e46a8419b1dbc 392 Pfam PF00155 Aminotransferase class I and II 27 384 8.8E-58 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS20960 e1e71ccb1b202b56233e46a8419b1dbc 392 Gene3D G3DSA:3.40.640.10 39 291 2.1E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 Gene3D G3DSA:3.40.50.720 124 294 1.5E-54 T 29-03-2018 MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 Gene3D G3DSA:3.40.50.720 1 123 5.5E-24 T 29-03-2018 MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 317 8.9E-14 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 SUPERFAMILY SSF52283 1 144 2.65E-18 T 29-03-2018 MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 SUPERFAMILY SSF51735 112 291 2.02E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04320 14cb81579df6afb118785f296cd6cd47 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 291 6.6E-60 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Gene3D G3DSA:3.30.300.30 417 522 9.3E-27 T 29-03-2018 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Gene3D G3DSA:3.40.50.980 9 175 1.7E-39 T 29-03-2018 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 SUPERFAMILY SSF56801 9 516 2.35E-146 T 29-03-2018 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 504 4.5E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Pfam PF00501 AMP-binding enzyme 19 422 3.6E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Gene3D G3DSA:2.30.38.10 328 415 3.4E-27 T 29-03-2018 MSG_RS09465 5351bee220b894f8e3e240de7cd8e860 522 Gene3D G3DSA:3.40.50.980 176 327 3.0E-37 T 29-03-2018 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 138 153 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 214 227 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 291 305 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 404 417 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 87 100 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 200 213 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 113 121 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 124 137 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 PRINTS PR00415 Aconitase family signature 348 359 1.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 Gene3D G3DSA:3.40.1060.10 159 293 3.7E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 6 464 3.8E-221 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 Gene3D G3DSA:3.30.499.10 1 158 3.6E-41 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 Pfam PF00330 Aconitase family (aconitate hydratase) 11 462 3.0E-157 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 5 471 59.676 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 ProSitePatterns PS01244 Aconitase family signature 2. 404 417 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 Gene3D G3DSA:3.30.499.10 330 471 1.4E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07830 d6e76cc306c15cf8d0ed93cf980283da 471 SUPERFAMILY SSF53732 5 469 3.01E-160 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS02415 7971ccab50706fa1652e6894617fa592 398 Gene3D G3DSA:3.40.50.1820 105 397 2.6E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02415 7971ccab50706fa1652e6894617fa592 398 Pfam PF00561 alpha/beta hydrolase fold 168 299 4.9E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02415 7971ccab50706fa1652e6894617fa592 398 SUPERFAMILY SSF53474 155 395 1.91E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS23925 75fe706816fbd4f1b23d8e397da1115c 312 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 291 9.4E-85 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS23925 75fe706816fbd4f1b23d8e397da1115c 312 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 1.3E-58 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS23925 75fe706816fbd4f1b23d8e397da1115c 312 SUPERFAMILY SSF53335 15 310 5.15E-73 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23925 75fe706816fbd4f1b23d8e397da1115c 312 Gene3D G3DSA:3.40.50.150 1 301 1.6E-54 T 29-03-2018 MSG_RS05450 ddffb94940bdabfed6844e48e4e3373d 207 SUPERFAMILY SSF69118 5 178 7.2E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS05450 ddffb94940bdabfed6844e48e4e3373d 207 Gene3D G3DSA:1.20.1290.10 18 185 2.9E-28 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 SMART SM00448 6 118 2.7E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 Pfam PF00072 Response regulator receiver domain 8 118 7.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.3E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 7.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 7.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 7.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 Gene3D G3DSA:3.40.50.2300 5 129 1.8E-28 T 29-03-2018 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 SUPERFAMILY SSF52172 6 174 5.5E-28 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 Gene3D G3DSA:1.10.10.10 130 220 4.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 SMART SM00421 153 210 1.1E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS22350 f6532f2a8c6b25c75632f88331c9644b 220 SUPERFAMILY SSF46894 153 215 5.1E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS07590 01e9e871263c7b710f6d5aabc4548264 316 SUPERFAMILY SSF48576 19 303 5.75E-69 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS07590 01e9e871263c7b710f6d5aabc4548264 316 Gene3D G3DSA:1.10.600.10 8 309 6.8E-87 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS07590 01e9e871263c7b710f6d5aabc4548264 316 Pfam PF00494 Squalene/phytoene synthase 29 287 1.6E-61 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 MSG_RS07590 01e9e871263c7b710f6d5aabc4548264 316 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 172 197 - T 29-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MSG_RS17940 edf44d62af28832b28e38badfc2d5cee 400 Gene3D G3DSA:3.20.20.140 4 396 1.7E-54 T 29-03-2018 MSG_RS17940 edf44d62af28832b28e38badfc2d5cee 400 SUPERFAMILY SSF51556 6 35 2.21E-61 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS17940 edf44d62af28832b28e38badfc2d5cee 400 SUPERFAMILY SSF51556 92 393 2.21E-61 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS17940 edf44d62af28832b28e38badfc2d5cee 400 Pfam PF04909 Amidohydrolase 89 393 2.1E-26 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 SUPERFAMILY SSF54292 283 383 1.84E-21 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00410 Phenol hydroxylase reductase family signature 259 267 1.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00410 Phenol hydroxylase reductase family signature 175 194 1.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00410 Phenol hydroxylase reductase family signature 90 102 1.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Pfam PF00970 Oxidoreductase FAD-binding domain 67 164 2.6E-8 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Gene3D G3DSA:3.10.20.30 290 383 2.4E-17 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 SUPERFAMILY SSF52343 155 282 4.45E-25 T 29-03-2018 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Gene3D G3DSA:3.40.50.80 163 289 8.9E-22 T 29-03-2018 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Gene3D G3DSA:2.40.30.10 64 159 9.0E-19 T 29-03-2018 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 SUPERFAMILY SSF63380 40 168 2.21E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 309 374 8.6E-10 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 90 100 2.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 175 194 2.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 109 116 2.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 223 2.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS05970 b6d383b68e1802179eaab7b7ca251cac 383 Pfam PF00175 Oxidoreductase NAD-binding domain 176 272 5.0E-9 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PIRSF PIRSF000114 1 343 7.5E-93 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 SUPERFAMILY SSF51735 8 185 8.29E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 205 229 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 63 90 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 180 204 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 140 160 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 245 262 2.1E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 Gene3D G3DSA:3.40.50.720 2 188 3.0E-40 T 29-03-2018 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 334 37.047 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 187 332 2.4E-47 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 165 2.5E-49 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 195 216 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 Gene3D G3DSA:1.10.1040.10 189 342 1.2E-48 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS07860 d3cd17851fdf7e4f47e9ffc808ef2a18 343 SUPERFAMILY SSF48179 186 343 4.25E-49 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 585 614 1.1E-4 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 300 1.5E-14 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 SMART SM00382 392 583 5.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 SMART SM00382 33 240 1.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 6.8E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Gene3D G3DSA:3.40.50.300 1 334 4.4E-71 T 29-03-2018 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Gene3D G3DSA:3.40.50.300 352 618 2.4E-69 T 29-03-2018 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Pfam PF00005 ABC transporter 384 533 1.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 Pfam PF00005 ABC transporter 26 182 3.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 SUPERFAMILY SSF52540 356 605 6.1E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18500 19dcc369d59e6dade7027fa1501093f5 619 SUPERFAMILY SSF52540 4 253 1.81E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 Pfam PF04055 Radical SAM superfamily 171 327 2.3E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 Pfam PF02310 B12 binding domain 38 129 1.0E-7 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 SMART SM00729 167 385 5.7E-13 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 Gene3D G3DSA:3.20.20.70 131 455 2.4E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 SUPERFAMILY SSF102114 158 364 5.89E-26 T 29-03-2018 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 Gene3D G3DSA:3.40.50.280 2 130 7.3E-7 T 29-03-2018 MSG_RS06965 e84a1641a38a17cc0c70b7d70caeb1bb 529 Pfam PF13282 Domain of unknown function (DUF4070) 359 514 1.7E-20 T 29-03-2018 IPR025274 Domain of unknown function DUF4070 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 436 4.5E-130 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PIRSF PIRSF004557 1 441 2.3E-115 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 SUPERFAMILY SSF103491 2 431 1.96E-120 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 440 29.511 T 29-03-2018 IPR026593 Protein translocase subunit SecY MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 Gene3D G3DSA:1.10.3370.10 1 441 1.4E-155 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 3.5E-100 T 29-03-2018 MSG_RS04695 278f31108a4015f60e70d44d75fed3cd 441 Pfam PF00344 SecY translocase 75 424 2.8E-114 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS08810 c901abca1b9a42f4186df1047e5441ad 115 Gene3D G3DSA:3.30.1310.10 1 114 4.4E-16 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS08810 c901abca1b9a42f4186df1047e5441ad 115 SUPERFAMILY SSF82607 11 89 1.57E-9 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS08810 c901abca1b9a42f4186df1047e5441ad 115 Pfam PF02575 YbaB/EbfC DNA-binding family 14 92 5.6E-11 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS07465 2ad569390eca89d9cebe356ee26fd3e7 290 SUPERFAMILY SSF52540 20 257 6.04E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS07465 2ad569390eca89d9cebe356ee26fd3e7 290 SMART SM00382 49 272 2.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS07465 2ad569390eca89d9cebe356ee26fd3e7 290 Pfam PF00005 ABC transporter 43 191 3.7E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS07465 2ad569390eca89d9cebe356ee26fd3e7 290 Gene3D G3DSA:3.40.50.300 12 268 6.6E-44 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 SUPERFAMILY SSF103473 241 412 1.16E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 SUPERFAMILY SSF103473 3 190 1.16E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 SUPERFAMILY SSF103473 464 491 1.16E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 Gene3D G3DSA:1.20.1250.20 252 497 1.5E-23 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 Gene3D G3DSA:1.20.1250.20 2 191 1.3E-29 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 254 279 2.2E-8 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 393 412 2.2E-8 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 2.2E-8 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 196 214 2.2E-8 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 2.2E-8 T 29-03-2018 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 Pfam PF07690 Major Facilitator Superfamily 11 402 3.3E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS05160 da81f29e1f87148d68a0f974080c82a0 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 7 413 1.2E-73 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MSG_RS08400 5d9d3a9ddf6e42114876d84d35501525 406 SMART SM00228 146 202 0.0087 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS08400 5d9d3a9ddf6e42114876d84d35501525 406 Pfam PF02163 Peptidase family M50 9 371 4.8E-53 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 MSG_RS08400 5d9d3a9ddf6e42114876d84d35501525 406 SUPERFAMILY SSF50156 99 209 2.63E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS08400 5d9d3a9ddf6e42114876d84d35501525 406 Gene3D G3DSA:2.30.42.10 143 243 3.8E-13 T 29-03-2018 MSG_RS23995 5684348e9511f67bc5768c507606721e 274 Gene3D G3DSA:3.90.226.10 1 223 3.7E-53 T 29-03-2018 MSG_RS23995 5684348e9511f67bc5768c507606721e 274 SUPERFAMILY SSF52096 4 273 4.69E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS23995 5684348e9511f67bc5768c507606721e 274 Gene3D G3DSA:1.10.12.10 224 273 2.3E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS23995 5684348e9511f67bc5768c507606721e 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 273 2.2E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS05670 0d5fe88e2ecb11328ec83b0360e10211 140 Gene3D G3DSA:3.30.750.24 14 129 1.8E-14 T 29-03-2018 IPR002645 STAS domain MSG_RS05670 0d5fe88e2ecb11328ec83b0360e10211 140 Pfam PF01740 STAS domain 28 105 3.0E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS05670 0d5fe88e2ecb11328ec83b0360e10211 140 SUPERFAMILY SSF52091 20 118 4.91E-12 T 29-03-2018 IPR002645 STAS domain MSG_RS01980 6ae7da80a2652fc644539ab06db527ed 339 Gene3D G3DSA:3.10.129.10 3 161 2.6E-18 T 29-03-2018 MSG_RS01980 6ae7da80a2652fc644539ab06db527ed 339 Gene3D G3DSA:3.10.129.10 193 339 1.5E-21 T 29-03-2018 MSG_RS01980 6ae7da80a2652fc644539ab06db527ed 339 SUPERFAMILY SSF54637 13 160 8.71E-29 T 29-03-2018 IPR029069 HotDog domain MSG_RS01980 6ae7da80a2652fc644539ab06db527ed 339 PIRSF PIRSF021494 7 339 1.3E-138 T 29-03-2018 IPR016790 Thiol ester hydratase, Rv0216, predicted KEGG: 00630+4.2.1.148|KEGG: 00660+4.2.1.148|KEGG: 00720+4.2.1.148|MetaCyc: PWY-5741|MetaCyc: PWY-5744|MetaCyc: PWY-6728|MetaCyc: PWY-7854 MSG_RS01980 6ae7da80a2652fc644539ab06db527ed 339 SUPERFAMILY SSF54637 192 337 2.11E-30 T 29-03-2018 IPR029069 HotDog domain MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 SUPERFAMILY SSF48179 268 469 2.11E-57 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 Gene3D G3DSA:3.40.50.720 6 266 2.7E-90 T 29-03-2018 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 Gene3D G3DSA:1.10.1040.10 267 470 5.0E-56 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 31 173 1.2E-27 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 PRINTS PR00084 Mannitol dehydrogenase signature 203 216 9.8E-16 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 PRINTS PR00084 Mannitol dehydrogenase signature 32 42 9.8E-16 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 PRINTS PR00084 Mannitol dehydrogenase signature 233 248 9.8E-16 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 PRINTS PR00084 Mannitol dehydrogenase signature 164 177 9.8E-16 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 202 441 1.5E-67 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MSG_RS20460 00824f126f9e61293d5f351b883b7b84 470 SUPERFAMILY SSF51735 15 267 1.57E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 SUPERFAMILY SSF51735 1 242 6.93E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 Gene3D G3DSA:3.40.50.720 1 274 2.4E-49 T 29-03-2018 MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 Pfam PF00106 short chain dehydrogenase 6 202 1.4E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06155 a9c34f0be36c951e35d244a5912f2c17 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS02650 b1acc8f9e1299d4f2b9bbe1d4a86f480 423 Pfam PF07907 YibE/F-like protein 162 400 1.4E-68 T 29-03-2018 IPR012507 YibE/F-like MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 Gene3D G3DSA:3.30.930.10 104 416 1.6E-80 T 29-03-2018 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PIRSF PIRSF001529 1 417 4.8E-132 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 4.7E-23 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 Gene3D G3DSA:1.10.287.40 1 102 6.5E-20 T 29-03-2018 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 SUPERFAMILY SSF55681 128 416 3.04E-85 T 29-03-2018 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 8.1E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 8.1E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 8.1E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 8.1E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 8.1E-30 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 38.025 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 SUPERFAMILY SSF46589 2 111 2.77E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 217 393 2.5E-25 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS24275 9ddc8ac559e22485dbbec291b4b025fd 417 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 409 3.1E-124 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 Pfam PF00696 Amino acid kinase family 30 272 1.6E-45 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 SUPERFAMILY SSF53633 11 295 2.62E-80 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 PIRSF PIRSF000728 15 294 3.0E-96 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 Hamap MF_00082_B Acetylglutamate kinase [argB]. 28 295 31.657 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 TIGRFAM TIGR00761 argB: acetylglutamate kinase 32 270 8.8E-79 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 PRINTS PR00474 Glutamate 5-kinase family signature 194 221 1.5E-7 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 PRINTS PR00474 Glutamate 5-kinase family signature 245 265 1.5E-7 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS11505 2cb12e85c20c1428c43d1328a374736e 296 Gene3D G3DSA:3.40.1160.10 2 296 5.7E-70 T 29-03-2018 MSG_RS07115 c76a16b7254b4078cb22074e462b8663 546 Gene3D G3DSA:3.20.20.80 67 437 9.3E-10 T 29-03-2018 MSG_RS07115 c76a16b7254b4078cb22074e462b8663 546 SUPERFAMILY SSF51445 236 337 2.66E-7 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS07115 c76a16b7254b4078cb22074e462b8663 546 SUPERFAMILY SSF51445 70 207 2.66E-7 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS01060 b5f0794b91ccf5f273feb12ebdb334ee 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 21.038 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS01060 b5f0794b91ccf5f273feb12ebdb334ee 78 Gene3D G3DSA:2.30.170.40 2 75 2.0E-25 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01060 b5f0794b91ccf5f273feb12ebdb334ee 78 SUPERFAMILY SSF143800 2 76 6.47E-26 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01060 b5f0794b91ccf5f273feb12ebdb334ee 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 5.4E-24 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS01060 b5f0794b91ccf5f273feb12ebdb334ee 78 Pfam PF00830 Ribosomal L28 family 4 61 3.9E-23 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 365 3.3E-130 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 1.2E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 1.2E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 1.2E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PRINTS PR00474 Glutamate 5-kinase family signature 215 235 1.2E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 1.2E-50 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 SUPERFAMILY SSF88697 280 365 9.39E-16 T 29-03-2018 IPR015947 PUA-like domain MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 SMART SM00359 280 359 1.1E-16 T 29-03-2018 IPR002478 PUA domain GO:0003723 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 Pfam PF01472 PUA domain 280 351 2.0E-16 T 29-03-2018 IPR002478 PUA domain GO:0003723 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 SUPERFAMILY SSF53633 14 258 1.44E-55 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 Gene3D G3DSA:3.40.1160.10 1 268 3.2E-53 T 29-03-2018 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 213 230 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 Gene3D G3DSA:2.30.130.10 278 366 4.6E-20 T 29-03-2018 IPR002478 PUA domain GO:0003723 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 Pfam PF00696 Amino acid kinase family 14 239 4.3E-35 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 264 33.813 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MSG_RS17135 ac627cc7ed6de1333f1e0109c93b850f 367 PIRSF PIRSF000729 7 367 5.5E-117 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 296 2.3E-67 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 Gene3D G3DSA:3.40.50.300 2 186 8.8E-57 T 29-03-2018 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 Gene3D G3DSA:1.10.287.890 199 287 4.6E-19 T 29-03-2018 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 Pfam PF01715 IPP transferase 41 291 2.0E-68 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 3 313 25.415 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 SUPERFAMILY SSF52540 5 149 2.17E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 SUPERFAMILY SSF52540 3 39 5.8E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 SUPERFAMILY SSF52540 172 235 5.8E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08920 2c04ffbbb1043dc73d257c1701919212 319 SUPERFAMILY SSF52540 265 311 5.8E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11580 f8e21d8a8b710eda20686186922136a1 530 Pfam PF00823 PPE family 8 164 4.5E-60 T 29-03-2018 IPR000030 PPE family MSG_RS11580 f8e21d8a8b710eda20686186922136a1 530 Gene3D G3DSA:1.10.287.1060 23 109 1.4E-5 T 29-03-2018 MSG_RS11580 f8e21d8a8b710eda20686186922136a1 530 SUPERFAMILY SSF140459 5 177 2.41E-61 T 29-03-2018 MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 SUPERFAMILY SSF54909 9 108 3.49E-22 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 Gene3D G3DSA:3.30.70.1060 1 113 8.3E-26 T 29-03-2018 MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 Gene3D G3DSA:3.30.70.1060 120 231 1.2E-21 T 29-03-2018 MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 SUPERFAMILY SSF54909 124 223 1.77E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 Pfam PF03795 YCII-related domain 143 218 4.9E-7 T 29-03-2018 IPR005545 YCII-related MSG_RS04125 75b1592c96bbb5e05e497861e9e17888 232 Pfam PF03795 YCII-related domain 15 108 1.4E-11 T 29-03-2018 IPR005545 YCII-related MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Gene3D G3DSA:3.40.50.140 15 161 5.2E-39 T 29-03-2018 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF01131 DNA topoisomerase 155 609 4.4E-116 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 SMART SM00437 299 572 2.7E-127 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 19 674 7.0E-259 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Gene3D G3DSA:2.70.20.10 374 511 9.8E-38 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 SMART SM00493 17 131 1.9E-36 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF13368 Topoisomerase C-terminal repeat 719 791 5.7E-13 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF13368 Topoisomerase C-terminal repeat 863 915 4.2E-20 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF13368 Topoisomerase C-terminal repeat 796 849 8.3E-17 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF13368 Topoisomerase C-terminal repeat 655 713 5.8E-6 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Pfam PF01751 Toprim domain 19 140 1.7E-27 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 SUPERFAMILY SSF56712 267 613 9.16E-174 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 SUPERFAMILY SSF56712 17 227 9.16E-174 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 SMART SM00436 131 219 7.9E-47 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Gene3D G3DSA:1.10.460.10 162 373 3.3E-41 T 29-03-2018 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Gene3D G3DSA:1.10.460.10 512 618 2.8E-21 T 29-03-2018 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 189 207 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 105 118 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 535 549 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 420 436 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 341 350 2.7E-34 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 Hamap MF_00952 DNA topoisomerase 1 [topA]. 17 808 54.856 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MSG_RS22985 f80f8353c4dbb679548c1fbc64f42ebf 946 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 336 350 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 PRINTS PR00050 Cold shock protein signature 4 19 1.0E-11 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 PRINTS PR00050 Cold shock protein signature 24 33 1.0E-11 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 PRINTS PR00050 Cold shock protein signature 38 56 1.0E-11 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 9.6E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 Gene3D G3DSA:2.40.50.140 2 74 6.5E-17 T 29-03-2018 MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 SUPERFAMILY SSF50249 2 68 1.89E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS20780 e724804f7f9d3fd0425ac96d5686db39 135 SMART SM00357 3 65 3.1E-22 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 SUPERFAMILY SSF51306 110 229 2.09E-35 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 Pfam PF01726 LexA DNA binding domain 21 83 3.6E-29 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 TIGRFAM TIGR00498 lexA: repressor LexA 21 231 7.0E-83 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 SUPERFAMILY SSF46785 21 87 9.67E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 Gene3D G3DSA:2.10.109.10 116 231 8.6E-27 T 29-03-2018 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 186 198 1.5E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 147 157 1.5E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 158 169 1.5E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 Hamap MF_00015 LexA repressor [lexA]. 21 231 33.242 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 Gene3D G3DSA:1.10.10.10 21 86 6.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08945 a35a9b77ce135fafe2bcc19591288369 231 Pfam PF00717 Peptidase S24-like 150 217 9.8E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 Gene3D G3DSA:3.90.380.10 155 455 1.6E-59 T 29-03-2018 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 56 71 1.4E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 77 97 1.4E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 1.4E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 Pfam PF00355 Rieske [2Fe-2S] domain 42 131 2.4E-13 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 SUPERFAMILY SSF50022 15 163 5.24E-41 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 Gene3D G3DSA:2.102.10.10 32 154 4.7E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 SUPERFAMILY SSF55961 163 298 5.42E-31 T 29-03-2018 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 SUPERFAMILY SSF55961 330 449 5.42E-31 T 29-03-2018 MSG_RS01130 e8b78e670bc9501ad1a15a8dca3f63fb 458 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 184 447 4.3E-21 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 260 2.3E-61 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 Pfam PF01255 Putative undecaprenyl diphosphate synthase 39 261 4.4E-67 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 Gene3D G3DSA:3.40.1180.10 18 262 8.1E-79 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 262 33.574 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 MSG_RS19595 59f07a721fcc3b7da42cf09b2995f06d 262 SUPERFAMILY SSF64005 28 256 1.7E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS19445 ed3cdf28605eaf03ffc2bf9dc1dbcabf 186 SUPERFAMILY SSF54001 5 105 1.72E-6 T 29-03-2018 MSG_RS19445 ed3cdf28605eaf03ffc2bf9dc1dbcabf 186 Gene3D G3DSA:3.90.1720.10 3 113 3.4E-6 T 29-03-2018 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 SUPERFAMILY SSF53474 5 270 5.88E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 Pfam PF12697 Alpha/beta hydrolase family 25 262 1.4E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 Gene3D G3DSA:3.40.50.1820 1 276 2.5E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 4.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 4.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 4.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00412 Epoxide hydrolase signature 213 229 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00412 Epoxide hydrolase signature 246 268 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS21435 ec76a181d273c027a039b8c39c0e32f3 276 PRINTS PR00412 Epoxide hydrolase signature 51 66 4.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 Gene3D G3DSA:2.40.110.10 115 209 3.8E-17 T 29-03-2018 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 372 1.3E-41 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 SUPERFAMILY SSF47203 230 379 6.66E-14 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 Gene3D G3DSA:1.20.140.10 210 394 3.7E-17 T 29-03-2018 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 SUPERFAMILY SSF56645 13 208 1.44E-34 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 Gene3D G3DSA:1.10.540.10 5 114 5.5E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22640 77770aa8aa487c57bc55506ca2e52d42 394 PIRSF PIRSF016578 1 394 5.0E-144 T 29-03-2018 MSG_RS16650 86fb4a88118fa5ebb9092ddac904b2e9 390 SUPERFAMILY SSF140459 5 174 6.02E-58 T 29-03-2018 MSG_RS16650 86fb4a88118fa5ebb9092ddac904b2e9 390 Pfam PF00823 PPE family 8 163 6.6E-59 T 29-03-2018 IPR000030 PPE family MSG_RS16650 86fb4a88118fa5ebb9092ddac904b2e9 390 Gene3D G3DSA:1.10.287.850 22 109 2.7E-7 T 29-03-2018 MSG_RS16650 86fb4a88118fa5ebb9092ddac904b2e9 390 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 292 386 4.2E-7 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS08545 2128293f5277500bbf1f95adc7c9a7e7 314 Pfam PF01368 DHH family 13 154 3.7E-12 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MSG_RS08545 2128293f5277500bbf1f95adc7c9a7e7 314 Gene3D G3DSA:3.90.1640.10 2 194 5.4E-36 T 29-03-2018 MSG_RS08545 2128293f5277500bbf1f95adc7c9a7e7 314 SUPERFAMILY SSF64182 13 298 7.19E-55 T 29-03-2018 MSG_RS08545 2128293f5277500bbf1f95adc7c9a7e7 314 Pfam PF02272 DHHA1 domain 233 313 1.7E-15 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MSG_RS14750 de6be9ba346857e2224cbca4aef6395a 299 Gene3D G3DSA:3.60.20.10 56 259 1.1E-33 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS14750 de6be9ba346857e2224cbca4aef6395a 299 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 59 284 1.2E-108 T 29-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 MSG_RS14750 de6be9ba346857e2224cbca4aef6395a 299 Hamap MF_02113_B Proteasome subunit beta [prcB]. 5 293 44.655 T 29-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 MSG_RS14750 de6be9ba346857e2224cbca4aef6395a 299 Pfam PF00227 Proteasome subunit 61 245 3.6E-26 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MSG_RS14750 de6be9ba346857e2224cbca4aef6395a 299 SUPERFAMILY SSF56235 57 276 2.04E-47 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 SUPERFAMILY SSF52467 184 334 2.5E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 167 1.6E-48 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 SUPERFAMILY SSF52518 359 538 1.67E-55 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Gene3D G3DSA:3.40.50.1220 182 339 1.9E-45 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Gene3D G3DSA:3.40.50.970 1 181 4.2E-47 T 29-03-2018 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Gene3D G3DSA:3.40.50.970 344 544 1.3E-40 T 29-03-2018 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 526 4.4E-40 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 324 1.4E-39 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MSG_RS02105 a5432164fbed824b8f2161b0d4210520 549 SUPERFAMILY SSF52518 3 177 3.76E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 459 38.639 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Pfam PF00206 Lyase 16 306 7.8E-58 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 SUPERFAMILY SSF48557 11 457 9.58E-129 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Gene3D G3DSA:1.20.200.10 113 380 2.8E-88 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Gene3D G3DSA:1.10.275.10 7 112 1.5E-27 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 6.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 6.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 6.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 6.4E-25 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Gene3D G3DSA:1.10.40.30 381 438 6.7E-26 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 457 1.4E-183 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 2.7E-52 T 29-03-2018 MSG_RS11530 9f16038da6162c4e7121170ab9dcc1d1 469 Pfam PF14698 Argininosuccinate lyase C-terminal 369 437 4.2E-22 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS18365 cbb4e5452cc1beae5b3d69187cc51a37 166 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 53 163 8.3E-37 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS18365 cbb4e5452cc1beae5b3d69187cc51a37 166 SUPERFAMILY SSF50475 50 158 1.36E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS18365 cbb4e5452cc1beae5b3d69187cc51a37 166 Pfam PF04075 F420H(2)-dependent quinone reductase 50 163 3.9E-26 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS18365 cbb4e5452cc1beae5b3d69187cc51a37 166 Gene3D G3DSA:2.30.110.10 31 166 1.2E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS02005 af585c86c63f7edd6082183a343844ef 400 Pfam PF07859 alpha/beta hydrolase fold 157 366 5.7E-22 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS02005 af585c86c63f7edd6082183a343844ef 400 Gene3D G3DSA:3.40.50.1820 66 390 4.0E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02005 af585c86c63f7edd6082183a343844ef 400 SUPERFAMILY SSF53474 114 368 9.23E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02005 af585c86c63f7edd6082183a343844ef 400 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 221 236 - T 29-03-2018 IPR019826 Carboxylesterase type B, active site MSG_RS04570 ec57d4e9f75dafa0c12b7d11980133fd 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.606 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z MSG_RS04570 ec57d4e9f75dafa0c12b7d11980133fd 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 4.4E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04570 ec57d4e9f75dafa0c12b7d11980133fd 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04570 ec57d4e9f75dafa0c12b7d11980133fd 61 Gene3D G3DSA:4.10.830.10 1 61 9.9E-23 T 29-03-2018 MSG_RS04570 ec57d4e9f75dafa0c12b7d11980133fd 61 SUPERFAMILY SSF57716 5 61 2.71E-21 T 29-03-2018 MSG_RS13335 0048ac1ae8f2ea1fc624236bdc982f98 209 SUPERFAMILY SSF55469 6 68 1.83E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13335 0048ac1ae8f2ea1fc624236bdc982f98 209 SUPERFAMILY SSF55469 97 207 1.83E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13335 0048ac1ae8f2ea1fc624236bdc982f98 209 Pfam PF00881 Nitroreductase family 14 180 5.4E-21 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS13335 0048ac1ae8f2ea1fc624236bdc982f98 209 Gene3D G3DSA:3.40.109.10 4 204 2.7E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 Pfam PF03949 Malic enzyme, NAD binding domain 265 525 3.2E-94 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 SUPERFAMILY SSF51735 265 540 1.15E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 Gene3D G3DSA:3.40.50.10380 10 262 1.6E-90 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 SUPERFAMILY SSF53223 13 264 2.66E-91 T 29-03-2018 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 Pfam PF00390 Malic enzyme, N-terminal domain 74 254 1.5E-65 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 Gene3D G3DSA:3.40.50.720 263 551 4.5E-94 T 29-03-2018 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 292 308 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 79 103 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 404 420 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 141 170 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 236 254 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 177 199 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PRINTS PR00072 Malic enzyme signature 261 277 8.1E-70 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 PIRSF PIRSF000106 4 552 7.7E-193 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 SMART SM01274 73 255 6.4E-83 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS16505 fc131f71e293c2891116ac07572b311a 552 SMART SM00919 265 526 1.1E-98 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 Gene3D G3DSA:3.10.25.10 207 310 7.7E-26 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 SUPERFAMILY SSF53328 2 206 4.84E-54 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 Pfam PF00551 Formyl transferase 16 179 1.5E-28 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 SUPERFAMILY SSF50486 205 304 2.67E-25 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 Gene3D G3DSA:3.40.50.170 1 206 4.2E-56 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 301 1.3E-22 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 302 1.4E-63 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MSG_RS10325 947737fe72e70a59b684cbca666eedad 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 304 30.203 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MSG_RS23630 5544f0472e77f210595ffa176a98e33c 329 Pfam PF00990 Diguanylate cyclase, GGDEF domain 189 329 1.2E-26 T 29-03-2018 IPR000160 GGDEF domain MSG_RS23630 5544f0472e77f210595ffa176a98e33c 329 SUPERFAMILY SSF55073 193 329 1.65E-28 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS23630 5544f0472e77f210595ffa176a98e33c 329 SMART SM00267 177 329 4.4E-18 T 29-03-2018 IPR000160 GGDEF domain MSG_RS23630 5544f0472e77f210595ffa176a98e33c 329 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 187 329 4.9E-27 T 29-03-2018 IPR000160 GGDEF domain MSG_RS23630 5544f0472e77f210595ffa176a98e33c 329 Gene3D G3DSA:3.30.70.270 181 329 6.4E-34 T 29-03-2018 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 464 3.4E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 SUPERFAMILY SSF56801 9 488 2.35E-101 T 29-03-2018 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Gene3D G3DSA:3.40.50.980 5 138 2.8E-24 T 29-03-2018 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Gene3D G3DSA:3.30.300.30 381 493 2.9E-20 T 29-03-2018 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Gene3D G3DSA:3.40.50.980 140 284 4.1E-29 T 29-03-2018 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Pfam PF00501 AMP-binding enzyme 146 386 1.4E-37 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Pfam PF00501 AMP-binding enzyme 17 108 5.4E-16 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02075 ac4ce77e83f6cf31eb4e0d022cbffa6f 496 Gene3D G3DSA:2.30.38.10 285 379 2.4E-12 T 29-03-2018 MSG_RS06670 1e1c9d3491a0cb7eef350da2357cdef3 217 SUPERFAMILY SSF53335 21 164 1.49E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS06670 1e1c9d3491a0cb7eef350da2357cdef3 217 Gene3D G3DSA:3.40.50.150 24 203 2.3E-16 T 29-03-2018 MSG_RS06670 1e1c9d3491a0cb7eef350da2357cdef3 217 Pfam PF13578 Methyltransferase domain 56 161 5.8E-12 T 29-03-2018 MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 Gene3D G3DSA:2.60.120.10 93 208 1.0E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 Pfam PF13560 Helix-turn-helix domain 25 81 1.5E-11 T 29-03-2018 MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 SUPERFAMILY SSF51182 94 200 5.44E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 SUPERFAMILY SSF47413 23 87 7.78E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 Pfam PF07883 Cupin domain 139 188 1.6E-6 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 SMART SM00530 28 83 9.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS09965 fe2e98fd9ef6ee7a835692bb1750722e 210 Gene3D G3DSA:1.10.260.40 18 91 2.6E-15 T 29-03-2018 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 SUPERFAMILY SSF53901 272 390 5.32E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 9.1E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 1.5E-42 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 Gene3D G3DSA:3.40.47.10 266 390 1.8E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.5E-97 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 SUPERFAMILY SSF53901 5 269 9.52E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 Gene3D G3DSA:3.40.47.10 1 265 2.5E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18135 d0d2648cf2839b6d95cc81d7315d5270 393 PIRSF PIRSF000429 1 393 1.7E-111 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 19 309 7.0E-147 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 14 309 54.686 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 PIRSF PIRSF002936 10 309 8.1E-141 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 SUPERFAMILY SSF52402 14 216 2.87E-64 T 29-03-2018 MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 Gene3D G3DSA:3.40.50.620 12 276 5.4E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS18450 3cd1ab0c87db5711fb50b9ddbea82162 309 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 262 9.4E-50 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MSG_RS08060 22ec28e1e3d699cdac59cdbb26954985 237 Pfam PF00975 Thioesterase domain 13 233 5.2E-47 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MSG_RS08060 22ec28e1e3d699cdac59cdbb26954985 237 SUPERFAMILY SSF53474 7 227 1.25E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08060 22ec28e1e3d699cdac59cdbb26954985 237 Gene3D G3DSA:3.40.50.1820 1 233 1.1E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20335 9a4f5f168395a761effa614a0f041eaa 282 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 258 1.2E-79 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS20335 9a4f5f168395a761effa614a0f041eaa 282 Pfam PF00296 Luciferase-like monooxygenase 18 230 4.2E-51 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20335 9a4f5f168395a761effa614a0f041eaa 282 SUPERFAMILY SSF51679 18 271 3.65E-58 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20335 9a4f5f168395a761effa614a0f041eaa 282 Gene3D G3DSA:3.20.20.30 16 241 3.0E-61 T 29-03-2018 MSG_RS01365 06fb7a720ebcdc526b0cbb52c96cc430 72 SUPERFAMILY SSF109755 9 52 1.44E-5 T 29-03-2018 MSG_RS15650 1bccb6ab8d0b8d66158d7cc1db6787f0 185 Pfam PF10862 FcoT-like thioesterase domain 31 181 2.7E-53 T 29-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like MSG_RS15650 1bccb6ab8d0b8d66158d7cc1db6787f0 185 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 22 185 1.0E-64 T 29-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like MSG_RS17520 9f062a5a32d0d5aed3ba28651e8fa6c2 398 SUPERFAMILY SSF141523 246 367 6.54E-27 T 29-03-2018 MSG_RS17520 9f062a5a32d0d5aed3ba28651e8fa6c2 398 Pfam PF03734 L,D-transpeptidase catalytic domain 248 367 3.2E-15 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS17520 9f062a5a32d0d5aed3ba28651e8fa6c2 398 Gene3D G3DSA:2.40.440.10 242 368 2.0E-23 T 29-03-2018 MSG_RS24500 ddff12036a8bb47a3442f4629d6d2bae 405 Gene3D G3DSA:1.10.287.1060 19 103 7.5E-4 T 29-03-2018 MSG_RS24500 ddff12036a8bb47a3442f4629d6d2bae 405 Pfam PF00823 PPE family 5 159 4.0E-48 T 29-03-2018 IPR000030 PPE family MSG_RS24500 ddff12036a8bb47a3442f4629d6d2bae 405 SUPERFAMILY SSF140459 2 174 2.62E-50 T 29-03-2018 MSG_RS17335 f8e5290c3904e028bafb732eb244afe1 670 Pfam PF05425 Copper resistance protein D 237 334 3.2E-18 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 MSG_RS17335 f8e5290c3904e028bafb732eb244afe1 670 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 386 631 7.0E-85 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 Pfam PF07969 Amidohydrolase family 48 555 2.5E-56 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 SUPERFAMILY SSF51338 502 567 1.61E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 SUPERFAMILY SSF51338 3 59 1.61E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 Gene3D G3DSA:3.20.20.140 69 497 8.5E-54 T 29-03-2018 MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 Gene3D G3DSA:2.30.40.10 1 68 2.7E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 SUPERFAMILY SSF51556 365 502 1.36E-63 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS03240 fbf1e123b8556b0217a8f676a5f78cdc 579 SUPERFAMILY SSF51556 60 316 1.36E-63 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS13635 f81ebb48af09dc3d5c1e8172fe4fc3b1 268 Gene3D G3DSA:2.40.33.20 1 268 2.2E-32 T 29-03-2018 MSG_RS13635 f81ebb48af09dc3d5c1e8172fe4fc3b1 268 Pfam PF03476 MOSC N-terminal beta barrel domain 2 51 1.2E-7 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel MSG_RS13635 f81ebb48af09dc3d5c1e8172fe4fc3b1 268 SUPERFAMILY SSF50800 2 46 1.15E-12 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MSG_RS13635 f81ebb48af09dc3d5c1e8172fe4fc3b1 268 SUPERFAMILY SSF50800 149 265 1.15E-12 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MSG_RS13635 f81ebb48af09dc3d5c1e8172fe4fc3b1 268 Pfam PF03473 MOSC domain 140 263 3.1E-10 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 PRINTS PR00502 NUDIX hydrolase family signature 60 75 2.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 PRINTS PR00502 NUDIX hydrolase family signature 46 60 2.3E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 Gene3D G3DSA:3.40.50.1240 155 290 7.7E-19 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 SMART SM00855 149 263 5.2E-10 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 Gene3D G3DSA:3.90.79.10 6 154 4.0E-32 T 29-03-2018 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 150 232 5.8E-13 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 SUPERFAMILY SSF53254 147 295 1.65E-21 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 Pfam PF00293 NUDIX domain 30 140 4.8E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS07845 e21a592be4f499f2eb1e7933d62bea12 311 SUPERFAMILY SSF55811 13 142 1.35E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS19680 fd49aee5f0e59b7acce49f8ebfdfd469 582 PIRSF PIRSF007542 4 582 3.7E-228 T 29-03-2018 IPR012037 Alpha/beta-hydrolase family MSG_RS19680 fd49aee5f0e59b7acce49f8ebfdfd469 582 Pfam PF10081 Alpha/beta-hydrolase family 287 574 3.8E-132 T 29-03-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain MSG_RS19680 fd49aee5f0e59b7acce49f8ebfdfd469 582 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 63 270 6.7E-70 T 29-03-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain MSG_RS14315 c688505ee30faf0923aef6a38eb3379f 312 SUPERFAMILY SSF56529 53 310 1.44E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS14315 c688505ee30faf0923aef6a38eb3379f 312 Gene3D G3DSA:3.90.850.10 14 312 1.3E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS14315 c688505ee30faf0923aef6a38eb3379f 312 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 67 310 1.1E-52 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS07530 266b128522540f1dace35a697eb9f3b1 162 PIRSF PIRSF005859 1 159 1.9E-32 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 MSG_RS07530 266b128522540f1dace35a697eb9f3b1 162 Pfam PF03073 TspO/MBR family 11 155 2.7E-31 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 MSG_RS20430 4a894d8fd9795f0fb8e02a3bf94bd9e7 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS20430 4a894d8fd9795f0fb8e02a3bf94bd9e7 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 267 3.9E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS20430 4a894d8fd9795f0fb8e02a3bf94bd9e7 269 SUPERFAMILY SSF52096 4 268 4.36E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20430 4a894d8fd9795f0fb8e02a3bf94bd9e7 269 Gene3D G3DSA:3.90.226.10 1 228 2.9E-56 T 29-03-2018 MSG_RS20430 4a894d8fd9795f0fb8e02a3bf94bd9e7 269 Gene3D G3DSA:1.10.12.10 229 268 6.0E-6 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS03375 15d8c5342759042174f9266ef4fa4e03 286 SUPERFAMILY SSF53335 12 286 1.22E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03375 15d8c5342759042174f9266ef4fa4e03 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 282 7.7E-110 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03375 15d8c5342759042174f9266ef4fa4e03 286 PIRSF PIRSF003085 5 286 1.2E-95 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS03375 15d8c5342759042174f9266ef4fa4e03 286 Gene3D G3DSA:3.40.50.150 2 286 9.4E-56 T 29-03-2018 MSG_RS08500 d90470275ddbea93736065f38a05bb6d 534 Gene3D G3DSA:1.20.1250.20 295 529 1.0E-20 T 29-03-2018 MSG_RS08500 d90470275ddbea93736065f38a05bb6d 534 Pfam PF07690 Major Facilitator Superfamily 65 453 2.1E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS08500 d90470275ddbea93736065f38a05bb6d 534 SUPERFAMILY SSF103473 44 243 2.35E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS08500 d90470275ddbea93736065f38a05bb6d 534 SUPERFAMILY SSF103473 291 513 2.35E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS08500 d90470275ddbea93736065f38a05bb6d 534 Gene3D G3DSA:1.20.1250.20 50 245 7.4E-28 T 29-03-2018 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 Gene3D G3DSA:2.40.50.140 36 113 4.1E-26 T 29-03-2018 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 36 107 6.0E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 SUPERFAMILY SSF50249 35 113 6.0E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 Pfam PF00366 Ribosomal protein S17 41 108 4.7E-28 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 36 111 23.026 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 36 107 1.1E-31 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 PRINTS PR00973 Ribosomal protein S17 family signature 55 78 6.1E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 PRINTS PR00973 Ribosomal protein S17 family signature 87 97 6.1E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 PRINTS PR00973 Ribosomal protein S17 family signature 97 104 6.1E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04505 b552417467a7eca517ab2ffc98249adf 114 ProSitePatterns PS00056 Ribosomal protein S17 signature. 87 99 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS01155 9ed1715057c7e699569060cfd7e6893e 476 Gene3D G3DSA:3.40.605.10 1 260 2.0E-82 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS01155 9ed1715057c7e699569060cfd7e6893e 476 SUPERFAMILY SSF53720 3 468 9.03E-150 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS01155 9ed1715057c7e699569060cfd7e6893e 476 Gene3D G3DSA:3.40.309.10 261 454 7.7E-62 T 29-03-2018 MSG_RS01155 9ed1715057c7e699569060cfd7e6893e 476 Pfam PF00171 Aldehyde dehydrogenase family 13 467 3.2E-148 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 PRINTS PR00409 Phthalate dioxygenase reductase family signature 127 146 3.2E-17 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 PRINTS PR00409 Phthalate dioxygenase reductase family signature 47 57 3.2E-17 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 PRINTS PR00409 Phthalate dioxygenase reductase family signature 105 119 3.2E-17 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 3.2E-17 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 PRINTS PR00409 Phthalate dioxygenase reductase family signature 205 213 3.2E-17 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 Gene3D G3DSA:3.10.20.30 233 329 2.4E-19 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 Gene3D G3DSA:3.40.50.80 117 232 2.8E-13 T 29-03-2018 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 SUPERFAMILY SSF63380 19 114 8.64E-18 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 SUPERFAMILY SSF52343 119 238 3.4E-20 T 29-03-2018 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 Gene3D G3DSA:2.40.30.10 18 115 9.1E-14 T 29-03-2018 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 251 322 3.4E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS09990 55c01a13567bf816020d072dde1a33c1 331 SUPERFAMILY SSF54292 227 323 1.31E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS06690 5f507d70d974005d88d4eb237f5a9ad4 421 Pfam PF01882 Protein of unknown function DUF58 190 272 8.1E-17 T 29-03-2018 IPR002881 Domain of unknown function DUF58 MSG_RS06690 5f507d70d974005d88d4eb237f5a9ad4 421 Gene3D G3DSA:3.40.50.410 202 415 9.8E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS14755 15fe43ea7d8093873d5ca8eee473bea4 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 2.8E-21 T 29-03-2018 IPR008515 Ubiquitin-like, Pup MSG_RS14755 15fe43ea7d8093873d5ca8eee473bea4 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.919 T 29-03-2018 IPR008515 Ubiquitin-like, Pup MSG_RS14755 15fe43ea7d8093873d5ca8eee473bea4 64 Pfam PF05639 Pup-like protein 3 64 3.9E-22 T 29-03-2018 IPR008515 Ubiquitin-like, Pup MSG_RS21750 0504365043ed854b39d8b1eecb84aea2 289 Gene3D G3DSA:3.30.470.10 2 112 2.9E-25 T 29-03-2018 MSG_RS21750 0504365043ed854b39d8b1eecb84aea2 289 Pfam PF01063 Amino-transferase class IV 29 261 2.0E-39 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MSG_RS21750 0504365043ed854b39d8b1eecb84aea2 289 SUPERFAMILY SSF56752 3 281 1.05E-50 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MSG_RS21750 0504365043ed854b39d8b1eecb84aea2 289 Gene3D G3DSA:3.20.10.10 116 278 1.7E-30 T 29-03-2018 MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 SMART SM00046 61 182 7.5E-7 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 Gene3D G3DSA:3.10.129.10 1 110 4.4E-24 T 29-03-2018 MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 SUPERFAMILY SSF54637 5 111 1.74E-11 T 29-03-2018 IPR029069 HotDog domain MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 SUPERFAMILY SSF54637 147 270 2.12E-7 T 29-03-2018 IPR029069 HotDog domain MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 Pfam PF13622 Thioesterase-like superfamily 24 270 8.0E-39 T 29-03-2018 MSG_RS03515 0705355d5cca04d60608d0d7fafc9285 274 Gene3D G3DSA:3.10.129.10 180 274 0.0025 T 29-03-2018 MSG_RS09580 51ce8ea3cf094f38a90c2b0111716f25 190 Gene3D G3DSA:3.30.428.10 9 190 2.4E-40 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS09580 51ce8ea3cf094f38a90c2b0111716f25 190 Pfam PF01230 HIT domain 66 154 1.6E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS09580 51ce8ea3cf094f38a90c2b0111716f25 190 SUPERFAMILY SSF54197 51 188 1.05E-37 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 7.3E-83 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 SUPERFAMILY SSF51569 4 340 1.78E-98 T 29-03-2018 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 Gene3D G3DSA:3.20.20.70 1 344 3.6E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 340 2.2E-152 T 29-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 PIRSF PIRSF001359 6 341 1.0E-65 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MSG_RS02835 41a406d78b67e9b5f4f59db2108deb66 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 5.7E-76 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 Gene3D G3DSA:3.10.580.10 229 375 4.1E-21 T 29-03-2018 MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 PIRSF PIRSF006404 1 377 6.1E-113 T 29-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 SMART SM00116 320 368 0.21 T 29-03-2018 IPR000644 CBS domain MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 SMART SM00116 254 303 9.6 T 29-03-2018 IPR000644 CBS domain MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 Pfam PF02163 Peptidase family M50 130 192 2.5E-9 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 Pfam PF00571 CBS domain 312 367 9.6E-10 T 29-03-2018 IPR000644 CBS domain MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 Pfam PF00571 CBS domain 247 300 2.4E-4 T 29-03-2018 IPR000644 CBS domain MSG_RS14065 7d5da41e7b20da6b37ffa0c2ca3f2833 393 SUPERFAMILY SSF54631 245 367 1.77E-18 T 29-03-2018 MSG_RS17190 61d26c845f192889cceb577586546f8d 197 Gene3D G3DSA:3.90.550.10 3 194 2.2E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS17190 61d26c845f192889cceb577586546f8d 197 SUPERFAMILY SSF53448 7 189 1.31E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS17190 61d26c845f192889cceb577586546f8d 197 Pfam PF12804 MobA-like NTP transferase domain 9 162 9.2E-26 T 29-03-2018 IPR025877 MobA-like NTP transferase MSG_RS17190 61d26c845f192889cceb577586546f8d 197 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 192 21.46 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 Gene3D G3DSA:3.50.50.60 141 298 1.1E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 Gene3D G3DSA:3.50.50.60 299 643 3.6E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 310 328 3.2E-5 T 29-03-2018 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 161 3.2E-5 T 29-03-2018 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 SUPERFAMILY SSF51905 142 366 2.59E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 SUPERFAMILY SSF51905 448 547 2.59E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13265 3ec96066bd4e7eef4e106a7c08e20f2c 646 Pfam PF00743 Flavin-binding monooxygenase-like 144 346 9.8E-14 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Gene3D G3DSA:1.10.540.10 342 458 1.5E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Gene3D G3DSA:1.20.140.10 559 725 3.5E-30 T 29-03-2018 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 465 558 7.3E-18 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 209 337 5.4E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 571 716 1.0E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 SUPERFAMILY SSF56645 383 584 1.57E-55 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 6.2E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 372 459 6.2E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 SUPERFAMILY SSF47203 571 717 4.03E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 SUPERFAMILY SSF47203 208 340 2.74E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Gene3D G3DSA:2.40.110.10 459 558 1.1E-30 T 29-03-2018 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 SUPERFAMILY SSF56645 4 204 1.28E-28 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Gene3D G3DSA:1.10.540.10 3 118 6.5E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS07260 fead5106f76b5d2ded8e2acd861cdccf 725 Gene3D G3DSA:1.20.140.10 204 334 8.0E-29 T 29-03-2018 MSG_RS11010 7010de98a081989d54945e7d4f1b1bc5 145 Gene3D G3DSA:2.30.110.10 7 144 3.1E-43 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS11010 7010de98a081989d54945e7d4f1b1bc5 145 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 142 3.0E-39 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS11010 7010de98a081989d54945e7d4f1b1bc5 145 SUPERFAMILY SSF50475 36 143 2.95E-6 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS11010 7010de98a081989d54945e7d4f1b1bc5 145 Pfam PF04075 F420H(2)-dependent quinone reductase 14 143 4.5E-54 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS03030 6c97fc6f41387d70444e422b37cb747a 251 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 249 5.2E-107 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MSG_RS03030 6c97fc6f41387d70444e422b37cb747a 251 Hamap MF_00443 Thiazole synthase [thiG]. 4 251 41.074 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MSG_RS03030 6c97fc6f41387d70444e422b37cb747a 251 SUPERFAMILY SSF110399 3 241 1.12E-82 T 29-03-2018 MSG_RS03030 6c97fc6f41387d70444e422b37cb747a 251 Gene3D G3DSA:3.20.20.70 2 251 3.3E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 SUPERFAMILY SSF52540 4 211 1.27E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 Pfam PF00271 Helicase conserved C-terminal domain 241 340 5.1E-21 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 Pfam PF00270 DEAD/DEAH box helicase 29 198 2.2E-43 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 SUPERFAMILY SSF52540 149 352 1.73E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 SMART SM00490 259 340 3.3E-24 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 Gene3D G3DSA:3.40.50.300 16 224 1.1E-48 T 29-03-2018 MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 SMART SM00487 24 224 7.8E-46 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS12510 bb702d0ab326c59dcf38e3e987f20a5a 458 Gene3D G3DSA:3.40.50.300 225 457 2.0E-38 T 29-03-2018 MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 SUPERFAMILY SSF51735 7 240 2.06E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 239 7.7E-64 T 29-03-2018 MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.5E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 Gene3D G3DSA:3.40.50.720 1 46 2.7E-6 T 29-03-2018 MSG_RS13835 c232feaf4d04b639abe92068490a517f 260 Gene3D G3DSA:3.40.50.720 47 251 2.5E-61 T 29-03-2018 MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 Gene3D G3DSA:1.10.260.40 45 65 3.5E-10 T 29-03-2018 MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 SUPERFAMILY SSF48498 86 180 4.45E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 SUPERFAMILY SSF46689 6 80 2.08E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 Gene3D G3DSA:1.10.10.60 2 44 1.0E-13 T 29-03-2018 MSG_RS03820 8078d9ddee9abbcb1dce592d1e81497b 182 Gene3D G3DSA:1.10.357.10 66 182 3.9E-10 T 29-03-2018 MSG_RS04615 b8fd360fd613e83a2e45b8e8482d8a5b 303 Gene3D G3DSA:3.40.50.150 3 282 2.1E-59 T 29-03-2018 MSG_RS04615 b8fd360fd613e83a2e45b8e8482d8a5b 303 Pfam PF04072 Leucine carboxyl methyltransferase 19 202 4.0E-66 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS04615 b8fd360fd613e83a2e45b8e8482d8a5b 303 SUPERFAMILY SSF53335 15 297 9.14E-80 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04615 b8fd360fd613e83a2e45b8e8482d8a5b 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 275 5.3E-83 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS12995 0eb6ce9b0c54deceec959ac6876d26cc 109 Pfam PF05305 Protein of unknown function (DUF732) 2 103 3.5E-17 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 Gene3D G3DSA:3.50.50.60 1 376 1.7E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 1.6E-38 T 29-03-2018 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 SUPERFAMILY SSF51905 5 185 2.89E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 SUPERFAMILY SSF51905 280 361 2.89E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15750 364fed2965cd6db75723323cc3e0c396 522 Pfam PF01494 FAD binding domain 6 355 1.6E-88 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Gene3D G3DSA:3.90.870.10 1 215 5.0E-94 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 PIRSF PIRSF001259 2 413 4.8E-176 T 29-03-2018 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 202 3.4E-72 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 403 56.788 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 212 404 3.2E-73 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 SUPERFAMILY SSF55821 5 208 1.74E-81 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 200 2.2E-84 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 SUPERFAMILY SSF142695 208 383 1.23E-67 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 407 39.751 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Pfam PF00925 GTP cyclohydrolase II 211 380 1.4E-72 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MSG_RS10365 4100511f0e03b539d79430052b71bcc1 425 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 206 37.67 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 SUPERFAMILY SSF82866 157 356 4.71E-28 T 29-03-2018 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 TIGRFAM TIGR00833 actII: transport protein 26 935 9.0E-301 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 Gene3D G3DSA:1.20.1170.10 351 677 1.2E-4 T 29-03-2018 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 SUPERFAMILY SSF82866 726 935 2.75E-33 T 29-03-2018 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 Pfam PF03176 MMPL family 615 943 3.3E-97 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 Pfam PF03176 MMPL family 60 388 1.0E-110 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 Gene3D G3DSA:1.20.1640.10 729 932 1.2E-27 T 29-03-2018 MSG_RS15685 09174f02ccf48595447a7175b856759a 976 Gene3D G3DSA:1.20.1640.10 136 350 9.1E-28 T 29-03-2018 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 SUPERFAMILY SSF48498 86 175 1.29E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 Gene3D G3DSA:1.10.10.60 2 60 6.5E-18 T 29-03-2018 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 Gene3D G3DSA:1.10.357.10 61 191 2.3E-20 T 29-03-2018 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 6.6E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09495 0ca7e2c8ba3ff4fa96b0fd8b6eef40cf 197 SUPERFAMILY SSF46689 6 82 2.67E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS10975 d048596774536a08ea4cb5e78df67a57 135 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 60 80 - T 29-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 MSG_RS10975 d048596774536a08ea4cb5e78df67a57 135 Gene3D G3DSA:1.10.490.10 4 135 9.6E-36 T 29-03-2018 MSG_RS10975 d048596774536a08ea4cb5e78df67a57 135 SUPERFAMILY SSF46458 9 125 4.76E-35 T 29-03-2018 IPR009050 Globin-like MSG_RS10975 d048596774536a08ea4cb5e78df67a57 135 Pfam PF01152 Bacterial-like globin 13 125 5.2E-31 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MSG_RS10975 d048596774536a08ea4cb5e78df67a57 135 PIRSF PIRSF002030 2 129 2.1E-45 T 29-03-2018 IPR016339 Truncated hemoglobin, group 1 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 SUPERFAMILY SSF51338 3 58 7.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 SUPERFAMILY SSF51338 504 570 7.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 Pfam PF07969 Amidohydrolase family 47 202 6.6E-14 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 Gene3D G3DSA:2.30.40.10 1 65 7.6E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 Gene3D G3DSA:3.20.20.140 66 500 3.0E-46 T 29-03-2018 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 Pfam PF01979 Amidohydrolase family 426 553 5.2E-6 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 SUPERFAMILY SSF51556 59 321 2.72E-44 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS08165 329f0d5d65a9870925ca09e1ce96530d 595 SUPERFAMILY SSF51556 370 501 2.72E-44 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 SUPERFAMILY SSF88688 400 525 2.09E-22 T 29-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 Pfam PF03065 Glycosyl hydrolase family 57 14 280 7.5E-18 T 29-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 SUPERFAMILY SSF88713 10 405 7.63E-96 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 Gene3D G3DSA:1.20.1430.10 407 526 4.9E-34 T 29-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 Pfam PF09210 Domain of unknown function (DUF1957) 442 522 1.7E-20 T 29-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MSG_RS07620 46052f5533328a78f3473f91f530b0f4 526 Gene3D G3DSA:3.20.110.10 7 405 3.2E-80 T 29-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain MSG_RS24350 f87700f688382a379b07a1ae1c0973eb 218 Gene3D G3DSA:1.25.40.120 4 218 7.2E-5 T 29-03-2018 MSG_RS23760 799e6fb67370b10d44647fdce7d12fb5 168 Pfam PF05154 TM2 domain 87 130 4.3E-8 T 29-03-2018 IPR007829 TM2 domain MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 546 1.2E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Gene3D G3DSA:3.30.450.40 1 178 4.9E-30 T 29-03-2018 IPR029016 GAF domain-like MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Pfam PF07730 Histidine kinase 355 420 5.5E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SUPERFAMILY SSF55781 12 196 1.18E-32 T 29-03-2018 IPR029016 GAF domain-like MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Gene3D G3DSA:3.30.450.40 204 355 3.1E-22 T 29-03-2018 IPR029016 GAF domain-like MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Pfam PF13185 GAF domain 29 168 8.9E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Pfam PF13185 GAF domain 204 338 3.9E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SUPERFAMILY SSF55781 204 352 1.53E-19 T 29-03-2018 IPR029016 GAF domain-like MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SMART SM00387 458 548 6.5E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SMART SM00065 199 348 0.002 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SMART SM00065 30 177 1.3E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 SUPERFAMILY SSF55874 443 546 1.96E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS13890 f21dc05b0672f1312c13d6825a6d31a6 549 Gene3D G3DSA:3.30.565.10 423 548 8.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS03735 58d4bc6a957dd02f768c18fef36c31e5 264 Gene3D G3DSA:3.40.50.1580 2 260 1.9E-40 T 29-03-2018 MSG_RS03735 58d4bc6a957dd02f768c18fef36c31e5 264 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 7 240 8.5E-89 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 MSG_RS03735 58d4bc6a957dd02f768c18fef36c31e5 264 SUPERFAMILY SSF53167 7 257 2.97E-72 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS03735 58d4bc6a957dd02f768c18fef36c31e5 264 Pfam PF01048 Phosphorylase superfamily 9 238 4.6E-37 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS03735 58d4bc6a957dd02f768c18fef36c31e5 264 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 6 259 37.805 T 29-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 SUPERFAMILY SSF64263 1 117 1.12E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 9.7E-42 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 Pfam PF01196 Ribosomal protein L17 20 116 3.4E-36 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 Gene3D G3DSA:3.90.1030.10 1 117 1.1E-46 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04850 1cbca62849ae3c407d5ac3bd23ec5898 182 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.876 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 Gene3D G3DSA:1.10.630.10 3 396 5.2E-60 T 29-03-2018 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 SUPERFAMILY SSF48264 19 395 1.31E-72 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 336 345 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 345 356 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 150 165 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 287 314 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 87 98 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 270 281 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 315 330 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 PRINTS PR00359 B-class P450 signature 133 149 3.8E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22520 2a30dc6528f77e5ac40ca3c75add9e84 396 Pfam PF00067 Cytochrome P450 147 365 4.4E-20 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 SUPERFAMILY SSF48498 94 209 1.22E-30 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 Gene3D G3DSA:1.10.10.60 1 71 1.7E-22 T 29-03-2018 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 2.4E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 Gene3D G3DSA:1.10.357.10 72 212 7.6E-15 T 29-03-2018 MSG_RS24380 ea11795b4c67c2abc7047954ea433762 212 SUPERFAMILY SSF46689 14 89 4.74E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15915 3fb83195f455cad23fa105c83a8573c6 336 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 165 305 3.0E-5 T 29-03-2018 MSG_RS15915 3fb83195f455cad23fa105c83a8573c6 336 Pfam PF12787 EcsC protein family 20 302 1.0E-26 T 29-03-2018 IPR024787 EcsC protein MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 SUPERFAMILY SSF50129 1 138 1.29E-32 T 29-03-2018 IPR011032 GroES-like MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 Pfam PF00107 Zinc-binding dehydrogenase 149 272 5.3E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 Gene3D G3DSA:3.40.50.720 135 288 1.7E-32 T 29-03-2018 MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 SMART SM00829 7 319 5.0E-35 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 SUPERFAMILY SSF51735 109 265 2.08E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 Gene3D G3DSA:3.90.180.10 1 134 1.8E-32 T 29-03-2018 MSG_RS06825 7fe2faa81fd8b5218a917d2555cc41b8 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 85 1.0E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 366 457 7.3E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 99 2.4E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 SUPERFAMILY SSF47203 569 715 9.99E-10 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 569 713 1.7E-10 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 211 343 1.1E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Gene3D G3DSA:1.10.540.10 335 459 5.0E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Gene3D G3DSA:1.10.540.10 2 128 7.8E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Gene3D G3DSA:2.40.110.10 460 556 1.7E-32 T 29-03-2018 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 SUPERFAMILY SSF47203 209 343 2.9E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Gene3D G3DSA:1.20.140.10 205 331 4.8E-26 T 29-03-2018 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 SUPERFAMILY SSF56645 4 196 5.36E-15 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 SUPERFAMILY SSF56645 369 582 7.07E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Gene3D G3DSA:1.20.140.10 557 717 1.3E-24 T 29-03-2018 MSG_RS22655 950792483225e4d685a1526bf9298d8f 717 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 461 545 2.8E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS08385 ac79a5fa75e64acd1c43c277ffe13d64 84 Pfam PF10939 Protein of unknown function (DUF2631) 2 64 3.8E-29 T 29-03-2018 IPR024341 Protein of unknown function DUF2631 MSG_RS08385 ac79a5fa75e64acd1c43c277ffe13d64 84 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 1 84 6.0E-21 T 29-03-2018 IPR024341 Protein of unknown function DUF2631 MSG_RS22080 db07cf7ecd1779f99202ee6c23b773f0 242 Pfam PF00589 Phage integrase family 77 196 2.4E-11 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS22080 db07cf7ecd1779f99202ee6c23b773f0 242 SUPERFAMILY SSF56349 74 204 1.59E-21 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MSG_RS22080 db07cf7ecd1779f99202ee6c23b773f0 242 Gene3D G3DSA:1.10.443.10 38 210 2.9E-22 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS01570 5289d5c44dbff73a008ea48b3904bae6 366 Gene3D G3DSA:3.40.50.720 1 189 1.0E-17 T 29-03-2018 MSG_RS01570 5289d5c44dbff73a008ea48b3904bae6 366 SUPERFAMILY SSF51735 1 170 2.1E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11440 706a9d7cb6ce2b1f3d0cef1f127f7dfa 469 Gene3D G3DSA:3.40.50.1820 117 441 3.9E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11440 706a9d7cb6ce2b1f3d0cef1f127f7dfa 469 SUPERFAMILY SSF53474 149 436 6.49E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11440 706a9d7cb6ce2b1f3d0cef1f127f7dfa 469 Pfam PF00756 Putative esterase 173 322 2.4E-11 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 240 1.5E-61 T 29-03-2018 MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 SUPERFAMILY SSF51735 2 240 3.55E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.1E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 2.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 Gene3D G3DSA:3.40.50.720 44 251 9.0E-60 T 29-03-2018 MSG_RS01105 44a035f4db3e2fb637c99b29d81619ce 257 Gene3D G3DSA:3.40.50.720 1 43 7.2E-8 T 29-03-2018 MSG_RS21685 c405c0064bf4611ac08248bf73b544b3 345 Gene3D G3DSA:1.10.3720.10 44 334 1.5E-30 T 29-03-2018 MSG_RS21685 c405c0064bf4611ac08248bf73b544b3 345 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 44 338 8.8E-79 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MSG_RS21685 c405c0064bf4611ac08248bf73b544b3 345 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 338 5.8E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS21685 c405c0064bf4611ac08248bf73b544b3 345 SUPERFAMILY SSF161098 75 332 2.62E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 500 36.581 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 254 271 1.8E-34 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 207 223 1.8E-34 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 236 249 1.8E-34 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 191 201 1.8E-34 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 383 399 1.8E-34 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 SUPERFAMILY SSF55681 154 498 1.64E-97 T 29-03-2018 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 Pfam PF00152 tRNA synthetases class II (D, K and N) 154 496 9.2E-70 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 Pfam PF01336 OB-fold nucleic acid binding domain 62 137 3.1E-12 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 SUPERFAMILY SSF50249 7 147 2.36E-35 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 Gene3D G3DSA:2.40.50.140 8 147 5.9E-38 T 29-03-2018 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 Gene3D G3DSA:3.30.930.10 149 497 1.1E-83 T 29-03-2018 MSG_RS22810 ba73c17fd641852420ce0e26adc186f8 502 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 500 5.6E-146 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS07140 bf0bf41f89be3c2e0ac9434886c79f42 507 Pfam PF00174 Oxidoreductase molybdopterin binding domain 233 380 1.4E-35 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MSG_RS07140 bf0bf41f89be3c2e0ac9434886c79f42 507 SUPERFAMILY SSF56524 210 403 8.37E-51 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MSG_RS07140 bf0bf41f89be3c2e0ac9434886c79f42 507 Gene3D G3DSA:2.60.40.650 403 507 1.9E-24 T 29-03-2018 MSG_RS07140 bf0bf41f89be3c2e0ac9434886c79f42 507 SUPERFAMILY SSF81296 396 506 3.36E-24 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS07140 bf0bf41f89be3c2e0ac9434886c79f42 507 Gene3D G3DSA:3.90.420.10 199 402 4.2E-49 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MSG_RS17800 c674821952425b005ef9645e6bd366ae 345 Pfam PF04909 Amidohydrolase 55 341 3.3E-31 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS17800 c674821952425b005ef9645e6bd366ae 345 Gene3D G3DSA:3.20.20.140 1 342 6.8E-43 T 29-03-2018 MSG_RS17800 c674821952425b005ef9645e6bd366ae 345 SUPERFAMILY SSF51556 50 341 3.74E-52 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 125 22.096 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 Gene3D G3DSA:1.20.5.220 104 125 4.4E-14 T 29-03-2018 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 1.3E-31 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.7E-6 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 1.7E-6 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 1.7E-6 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 SUPERFAMILY SSF81330 11 118 7.98E-25 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS20215 9a491ba2eec32784a633eee986f24e6a 149 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 9.8E-23 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MSG_RS04140 404bd0980a83b99605abc43fb59f703c 287 Gene3D G3DSA:3.40.50.150 2 287 7.7E-54 T 29-03-2018 MSG_RS04140 404bd0980a83b99605abc43fb59f703c 287 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 283 5.4E-122 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04140 404bd0980a83b99605abc43fb59f703c 287 SUPERFAMILY SSF53335 13 287 3.57E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04140 404bd0980a83b99605abc43fb59f703c 287 PIRSF PIRSF003085 2 287 9.4E-113 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 3 462 2.7E-202 T 29-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 SUPERFAMILY SSF54631 333 461 2.15E-18 T 29-03-2018 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Gene3D G3DSA:3.40.50.1100 41 142 1.3E-32 T 29-03-2018 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Gene3D G3DSA:3.10.580.10 328 463 4.8E-18 T 29-03-2018 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Pfam PF00571 CBS domain 410 462 6.8E-6 T 29-03-2018 IPR000644 CBS domain MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Pfam PF00571 CBS domain 346 399 7.9E-7 T 29-03-2018 IPR000644 CBS domain MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 300 6.1E-61 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 SMART SM00116 417 462 1.4 T 29-03-2018 IPR000644 CBS domain MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 SMART SM00116 347 400 3.4E-4 T 29-03-2018 IPR000644 CBS domain MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 SUPERFAMILY SSF53686 1 321 2.62E-90 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS19645 51af59ab74b9186e5ed6cf7e5195286b 468 Gene3D G3DSA:3.40.50.1100 143 320 6.0E-49 T 29-03-2018 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 SUPERFAMILY SSF55973 126 252 1.49E-45 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 279 287 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 251 2.6E-44 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 SUPERFAMILY SSF55973 253 401 7.46E-67 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 PIRSF PIRSF000497 1 403 4.4E-160 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 106 9.5E-37 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Gene3D G3DSA:3.30.300.10 13 152 2.2E-39 T 29-03-2018 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 402 4.7E-162 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 SUPERFAMILY SSF55973 6 114 5.49E-41 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 403 56.27 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Gene3D G3DSA:3.30.300.10 157 278 8.3E-41 T 29-03-2018 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 253 392 4.1E-66 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MSG_RS10270 78df22a36673954106b9145198dea0eb 403 Gene3D G3DSA:3.30.300.10 279 403 2.3E-46 T 29-03-2018 MSG_RS21100 69afa77e8434b46f51b3c1563a94648d 470 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 303 1.1E-66 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21100 69afa77e8434b46f51b3c1563a94648d 470 Pfam PF02470 MlaD protein 46 118 3.2E-10 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS21100 69afa77e8434b46f51b3c1563a94648d 470 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 171 292 7.4E-9 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS13280 d08bf7e5b4f84231afd91f615f67cdf3 303 SUPERFAMILY SSF53335 23 287 2.93E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS13280 d08bf7e5b4f84231afd91f615f67cdf3 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 25 280 3.4E-81 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS13280 d08bf7e5b4f84231afd91f615f67cdf3 303 Pfam PF04072 Leucine carboxyl methyltransferase 27 202 1.1E-54 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS13280 d08bf7e5b4f84231afd91f615f67cdf3 303 Gene3D G3DSA:3.40.50.150 11 285 4.9E-47 T 29-03-2018 MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 Pfam PF04536 TPM domain 381 497 3.7E-9 T 29-03-2018 IPR007621 TPM domain MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 Gene3D G3DSA:1.10.510.10 86 392 4.1E-42 T 29-03-2018 MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 Gene3D G3DSA:3.30.200.20 12 85 3.1E-13 T 29-03-2018 MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 Pfam PF00069 Protein kinase domain 16 267 6.6E-40 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 SUPERFAMILY SSF56112 15 278 4.59E-62 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS11200 7b97a1e4f1b8e7c78f7401cc6e44d2a0 502 SMART SM00220 16 277 2.8E-49 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS17890 afe90a73897af91571e58761c8c63a58 405 SUPERFAMILY SSF89796 1 404 3.4E-89 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17890 afe90a73897af91571e58761c8c63a58 405 Gene3D G3DSA:3.40.50.10540 1 405 8.1E-87 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17890 afe90a73897af91571e58761c8c63a58 405 Pfam PF02515 CoA-transferase family III 1 381 1.7E-75 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS15640 4484b63039e9bbfb3c3e09961a8c4cea 476 Gene3D G3DSA:1.10.287.1060 15 108 1.3E-4 T 29-03-2018 MSG_RS15640 4484b63039e9bbfb3c3e09961a8c4cea 476 SUPERFAMILY SSF140459 1 171 1.91E-57 T 29-03-2018 MSG_RS15640 4484b63039e9bbfb3c3e09961a8c4cea 476 Pfam PF00823 PPE family 2 158 1.7E-58 T 29-03-2018 IPR000030 PPE family MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 228 4.6E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 SUPERFAMILY SSF56645 8 253 3.8E-61 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Gene3D G3DSA:2.40.110.10 129 228 8.9E-34 T 29-03-2018 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Gene3D G3DSA:1.20.140.10 229 404 6.6E-48 T 29-03-2018 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Gene3D G3DSA:1.10.540.10 1 128 5.3E-25 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 390 6.5E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 SUPERFAMILY SSF47203 238 396 7.41E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01535 b46982ad8de084b3c9a336178f57e5e1 406 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 124 2.9E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 Pfam PF00067 Cytochrome P450 101 394 9.5E-18 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 171 186 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 365 374 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 154 170 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 374 385 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 343 358 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 315 342 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 107 118 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 216 238 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 PRINTS PR00359 B-class P450 signature 298 309 3.2E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 SUPERFAMILY SSF48264 28 416 6.81E-82 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17125 e99f7f2a5106d2691799f85a83ea4e71 421 Gene3D G3DSA:1.10.630.10 1 421 5.5E-65 T 29-03-2018 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-21 T 29-03-2018 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.1E-21 T 29-03-2018 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.1E-21 T 29-03-2018 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.1E-21 T 29-03-2018 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 Pfam PF01494 FAD binding domain 7 343 4.2E-48 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 Gene3D G3DSA:3.50.50.60 5 350 5.5E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 SUPERFAMILY SSF51905 274 355 3.51E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05050 cf84a16ae0acc8add91ef881649738eb 413 SUPERFAMILY SSF51905 7 176 3.51E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00985 f8f91ab18cfc3b331c735192b6d6d0a9 254 PIRSF PIRSF021485 1 254 1.0E-116 T 29-03-2018 IPR014511 Protein of unknown function DUF2068, transmembrane, subgroup MSG_RS00985 f8f91ab18cfc3b331c735192b6d6d0a9 254 Pfam PF09900 Predicted membrane protein (DUF2127) 81 222 9.5E-34 T 29-03-2018 IPR021125 Protein of unknown function DUF2127 MSG_RS14650 7a05c3c80488f0abe30f8a45a84e7746 136 SUPERFAMILY SSF50475 9 127 3.93E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS14650 7a05c3c80488f0abe30f8a45a84e7746 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 13 127 9.3E-29 T 29-03-2018 IPR019920 F420-binding domain, putative MSG_RS14650 7a05c3c80488f0abe30f8a45a84e7746 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 92 1.4E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS14650 7a05c3c80488f0abe30f8a45a84e7746 136 Gene3D G3DSA:2.30.110.10 1 130 4.6E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS20510 db374a57882a5f548247caa8a8316ad3 273 SUPERFAMILY SSF51679 5 262 7.07E-38 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20510 db374a57882a5f548247caa8a8316ad3 273 Gene3D G3DSA:3.20.20.30 13 272 4.1E-36 T 29-03-2018 MSG_RS20510 db374a57882a5f548247caa8a8316ad3 273 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 5 272 3.8E-100 T 29-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted MSG_RS20510 db374a57882a5f548247caa8a8316ad3 273 Pfam PF00296 Luciferase-like monooxygenase 17 199 1.6E-24 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 SUPERFAMILY SSF53187 300 385 3.18E-69 T 29-03-2018 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 SUPERFAMILY SSF53187 9 199 3.18E-69 T 29-03-2018 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 PIRSF PIRSF005962 9 388 3.2E-93 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 375 1.9E-95 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 SUPERFAMILY SSF55031 184 301 3.59E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS05575 b587b7739f56a955065e0c741f108853 392 Gene3D G3DSA:3.40.630.10 2 214 1.3E-41 T 29-03-2018 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 Gene3D G3DSA:3.40.630.10 215 391 5.9E-18 T 29-03-2018 MSG_RS05575 b587b7739f56a955065e0c741f108853 392 Pfam PF01546 Peptidase family M20/M25/M40 75 384 2.1E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MSG_RS01610 dcd7fdb31539db4f198e0626bc99c6e7 293 SUPERFAMILY SSF54637 127 279 2.89E-25 T 29-03-2018 IPR029069 HotDog domain MSG_RS01610 dcd7fdb31539db4f198e0626bc99c6e7 293 Gene3D G3DSA:3.10.129.10 5 118 3.5E-18 T 29-03-2018 MSG_RS01610 dcd7fdb31539db4f198e0626bc99c6e7 293 Pfam PF13622 Thioesterase-like superfamily 46 277 2.1E-28 T 29-03-2018 MSG_RS01610 dcd7fdb31539db4f198e0626bc99c6e7 293 Gene3D G3DSA:3.10.129.10 130 281 9.4E-24 T 29-03-2018 MSG_RS01610 dcd7fdb31539db4f198e0626bc99c6e7 293 SUPERFAMILY SSF54637 10 115 3.04E-17 T 29-03-2018 IPR029069 HotDog domain MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 Gene3D G3DSA:3.40.640.10 48 257 2.6E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 SUPERFAMILY SSF53383 31 362 8.57E-71 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 Gene3D G3DSA:3.90.1150.10 258 364 2.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 Pfam PF00155 Aminotransferase class I and II 32 353 8.7E-56 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 364 53.272 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MSG_RS11160 85a7aaf9e91f5ddf942418c8789677ab 375 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 14 362 5.5E-101 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 Gene3D G3DSA:1.20.1640.10 152 365 5.7E-27 T 29-03-2018 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 Pfam PF03176 MMPL family 65 393 8.9E-100 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 Pfam PF03176 MMPL family 620 948 1.0E-82 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 SUPERFAMILY SSF82866 144 362 9.68E-29 T 29-03-2018 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 Gene3D G3DSA:1.20.1640.10 719 937 6.8E-25 T 29-03-2018 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 TIGRFAM TIGR00833 actII: transport protein 32 940 2.7E-277 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 SUPERFAMILY SSF82866 731 940 1.57E-29 T 29-03-2018 MSG_RS06910 b1421c0f1790e1669723a98dfc6a353c 975 Gene3D G3DSA:1.10.287.500 500 575 0.14 T 29-03-2018 MSG_RS03510 b6730e8aee4a4fc55b92bb3d066d55d3 280 SUPERFAMILY SSF51658 4 263 9.54E-40 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS03510 b6730e8aee4a4fc55b92bb3d066d55d3 280 Pfam PF01261 Xylose isomerase-like TIM barrel 23 229 1.1E-13 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MSG_RS03510 b6730e8aee4a4fc55b92bb3d066d55d3 280 Gene3D G3DSA:3.20.20.150 2 280 1.7E-46 T 29-03-2018 MSG_RS22735 3a4584d07af838a1dce0fc115e5f4e02 162 Pfam PF02559 CarD-like/TRCF domain 3 111 6.5E-20 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS22735 3a4584d07af838a1dce0fc115e5f4e02 162 SUPERFAMILY SSF141259 3 66 3.01E-15 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS22735 3a4584d07af838a1dce0fc115e5f4e02 162 SMART SM01058 2 112 1.3E-34 T 29-03-2018 IPR003711 CarD-like/TRCF domain MSG_RS23330 ebb8a4c63954c31496c3431847277daa 490 PIRSF PIRSF012666 1 490 2.0E-236 T 29-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 MSG_RS23330 ebb8a4c63954c31496c3431847277daa 490 SUPERFAMILY SSF55931 37 456 6.47E-44 T 29-03-2018 MSG_RS01360 112ad0eb837ad3b7f290887371a32534 444 Gene3D G3DSA:3.40.50.980 86 264 1.6E-7 T 29-03-2018 MSG_RS01360 112ad0eb837ad3b7f290887371a32534 444 SUPERFAMILY SSF56801 44 400 2.88E-22 T 29-03-2018 MSG_RS06455 ba7a647b7c29671892b0063cc46b9cb7 149 Gene3D G3DSA:2.60.40.790 2 129 6.4E-27 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS06455 ba7a647b7c29671892b0063cc46b9cb7 149 Pfam PF00011 Hsp20/alpha crystallin family 32 128 9.3E-23 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MSG_RS06455 ba7a647b7c29671892b0063cc46b9cb7 149 SUPERFAMILY SSF49764 4 128 2.09E-29 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 Gene3D G3DSA:3.40.50.1000 86 184 3.1E-27 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 Gene3D G3DSA:3.40.50.1000 6 85 4.7E-4 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 12 231 7.0E-32 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 SUPERFAMILY SSF56784 8 257 2.66E-48 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 108 1.1E-19 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 Pfam PF13242 HAD-hyrolase-like 184 256 4.8E-15 T 29-03-2018 MSG_RS11685 10b3f6318a7af2872cf0250802ac3c9c 336 PIRSF PIRSF000915 1 260 1.6E-56 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 Pfam PF00135 Carboxylesterase family 9 487 9.3E-100 T 29-03-2018 IPR002018 Carboxylesterase, type B MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 Gene3D G3DSA:3.40.50.1820 1 499 8.9E-128 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 103 118 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 181 196 - T 29-03-2018 IPR019826 Carboxylesterase type B, active site MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 82 92 - T 29-03-2018 IPR019819 Carboxylesterase type B, conserved site MSG_RS14500 5baa2e08207fc30575d0dea25f14ce88 501 SUPERFAMILY SSF53474 6 497 3.37E-117 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 Gene3D G3DSA:3.90.650.10 160 306 1.7E-32 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 Hamap MF_00625 Selenide, water dikinase [selD]. 3 325 34.95 T 29-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 PIRSF PIRSF036407 1 307 1.1E-96 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 Gene3D G3DSA:3.30.1330.10 1 159 6.8E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 SUPERFAMILY SSF56042 159 322 3.14E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 SUPERFAMILY SSF55326 5 157 8.07E-39 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 170 304 1.3E-16 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 TIGRFAM TIGR00476 selD: selenide, water dikinase 5 304 2.0E-114 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MSG_RS00725 ddd328e94acf0960f4a2d9f5c7418f67 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 47 152 2.6E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS04360 410fce5dfcf6307d7144db79741895f2 470 TIGRFAM TIGR03965 mycofact_glyco: mycofactocin system glycosyltransferase 12 469 4.3E-185 T 29-03-2018 IPR023981 Putative mycofactocin biosynthesis glycosyltransferase MSG_RS04360 410fce5dfcf6307d7144db79741895f2 470 Gene3D G3DSA:3.90.550.10 57 299 2.1E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS04360 410fce5dfcf6307d7144db79741895f2 470 SUPERFAMILY SSF53448 81 326 9.85E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS04360 410fce5dfcf6307d7144db79741895f2 470 Pfam PF00535 Glycosyl transferase family 2 85 242 1.4E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS05905 0e116439af3723d0301027016a49af4b 228 SMART SM00448 6 116 1.1E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05905 0e116439af3723d0301027016a49af4b 228 Gene3D G3DSA:3.40.50.2300 3 123 2.6E-37 T 29-03-2018 MSG_RS05905 0e116439af3723d0301027016a49af4b 228 Pfam PF00072 Response regulator receiver domain 8 117 3.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05905 0e116439af3723d0301027016a49af4b 228 SUPERFAMILY SSF52172 6 182 4.55E-44 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS05905 0e116439af3723d0301027016a49af4b 228 Gene3D G3DSA:1.10.10.10 124 228 6.4E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05905 0e116439af3723d0301027016a49af4b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 8.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS05905 0e116439af3723d0301027016a49af4b 228 SMART SM00862 149 225 2.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 Gene3D G3DSA:3.10.180.10 133 299 3.3E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 29-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 267 1.0E-19 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 SUPERFAMILY SSF54593 135 292 2.28E-33 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 Gene3D G3DSA:3.10.180.10 1 132 1.1E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22630 a006ca7f78024c72925c25709cd1130a 300 SUPERFAMILY SSF54593 1 123 1.28E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 ProSitePatterns PS00455 Putative AMP-binding domain signature. 52 63 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Gene3D G3DSA:3.30.300.30 269 375 2.3E-24 T 29-03-2018 MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Gene3D G3DSA:3.40.50.980 57 208 4.4E-28 T 29-03-2018 MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Pfam PF00501 AMP-binding enzyme 45 273 1.2E-30 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Pfam PF13193 AMP-binding enzyme C-terminal domain 284 359 6.0E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Gene3D G3DSA:2.30.38.10 209 268 9.9E-8 T 29-03-2018 MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 Gene3D G3DSA:3.40.50.980 5 56 6.9E-7 T 29-03-2018 MSG_RS03775 60fe3292868036c367206ca00e1f24cc 375 SUPERFAMILY SSF56801 26 371 4.58E-72 T 29-03-2018 MSG_RS08670 f170ff03ef7fa78d03bc1825cb86193b 349 SUPERFAMILY SSF50022 10 120 1.15E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS08670 f170ff03ef7fa78d03bc1825cb86193b 349 Pfam PF00355 Rieske [2Fe-2S] domain 13 95 1.2E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS08670 f170ff03ef7fa78d03bc1825cb86193b 349 SUPERFAMILY SSF55961 121 324 1.7E-11 T 29-03-2018 MSG_RS08670 f170ff03ef7fa78d03bc1825cb86193b 349 Gene3D G3DSA:3.90.380.10 105 325 4.9E-18 T 29-03-2018 MSG_RS08670 f170ff03ef7fa78d03bc1825cb86193b 349 Gene3D G3DSA:2.102.10.10 10 104 3.1E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 Pfam PF00501 AMP-binding enzyme 11 466 2.3E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 Gene3D G3DSA:3.40.50.980 3 169 1.6E-28 T 29-03-2018 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 Gene3D G3DSA:3.30.300.30 460 568 1.6E-15 T 29-03-2018 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 Gene3D G3DSA:3.40.50.980 170 361 1.1E-28 T 29-03-2018 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 Gene3D G3DSA:2.30.38.10 377 459 3.6E-21 T 29-03-2018 MSG_RS10915 8e8453a5927bccc566ca2ad0cd46d7d0 577 SUPERFAMILY SSF56801 5 570 3.27E-96 T 29-03-2018 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 Pfam PF02913 FAD linked oxidases, C-terminal domain 278 527 2.1E-46 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 SUPERFAMILY SSF56176 53 278 4.07E-45 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 Gene3D G3DSA:3.30.465.10 157 300 6.1E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 SUPERFAMILY SSF55103 285 529 2.78E-40 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 Gene3D G3DSA:1.10.45.10 489 527 5.0E-13 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 Pfam PF01565 FAD binding domain 106 238 8.7E-31 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS15770 3d3cb4330616061e4d147a24da418deb 529 Gene3D G3DSA:3.30.43.10 41 156 1.1E-15 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 Gene3D G3DSA:3.10.129.10 178 341 1.1E-28 T 29-03-2018 MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 Pfam PF13452 N-terminal half of MaoC dehydratase 14 141 5.9E-30 T 29-03-2018 MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 Pfam PF01575 MaoC like domain 220 291 1.6E-16 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 Gene3D G3DSA:3.10.129.10 5 159 3.4E-25 T 29-03-2018 MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 SUPERFAMILY SSF54637 205 314 1.39E-20 T 29-03-2018 IPR029069 HotDog domain MSG_RS18195 ab06e1b1905438a0435b755a379d01ea 343 SUPERFAMILY SSF54637 22 152 7.47E-27 T 29-03-2018 IPR029069 HotDog domain MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 SUPERFAMILY SSF48264 19 413 8.51E-81 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 142 158 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 353 362 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 303 330 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 203 225 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 362 373 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 159 174 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 286 297 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 PRINTS PR00359 B-class P450 signature 96 107 2.5E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 Pfam PF00067 Cytochrome P450 287 383 2.3E-14 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 Gene3D G3DSA:1.10.630.10 3 413 8.3E-60 T 29-03-2018 MSG_RS18665 bbf1d97d00ec62063ea1ff1e1d044e12 413 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 SUPERFAMILY SSF52440 2 113 5.61E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 SUPERFAMILY SSF51230 582 652 9.06E-18 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Pfam PF00364 Biotin-requiring enzyme 587 652 3.8E-14 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 1.1E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 SUPERFAMILY SSF51246 333 447 5.23E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Pfam PF02785 Biotin carboxylase C-terminal domain 338 445 4.7E-34 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Gene3D G3DSA:3.40.50.20 1 121 2.2E-50 T 29-03-2018 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Gene3D G3DSA:2.40.50.100 583 653 8.9E-14 T 29-03-2018 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 610 627 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Gene3D G3DSA:3.30.470.20 204 447 7.2E-104 T 29-03-2018 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 SUPERFAMILY SSF56059 83 350 2.12E-67 T 29-03-2018 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 SMART SM00878 338 444 1.6E-49 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 1.1E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MSG_RS17465 be8cb6d637f17a45eb2349ad9221a785 663 Gene3D G3DSA:3.30.1490.20 122 202 1.2E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Pfam PF02875 Mur ligase family, glutamate ligase domain 350 440 4.3E-25 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Pfam PF01225 Mur ligase family, catalytic domain 34 98 4.3E-10 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Pfam PF08245 Mur ligase middle domain 136 328 4.3E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 36 506 6.5E-132 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 SUPERFAMILY SSF53244 350 506 3.43E-29 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 SUPERFAMILY SSF53623 131 344 8.37E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 SUPERFAMILY SSF63418 5 86 5.49E-16 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Gene3D G3DSA:3.40.1190.10 118 344 3.2E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Gene3D G3DSA:3.90.190.20 348 519 2.0E-46 T 29-03-2018 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Gene3D G3DSA:3.40.1390.10 2 117 5.1E-26 T 29-03-2018 MSG_RS15110 15309437deebb3b41137c4b9d2f735ab 520 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 507 30.046 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS11305 64d8879e506a3031a54772088391171b 208 PIRSF PIRSF036382 5 202 1.5E-74 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator MSG_RS11305 64d8879e506a3031a54772088391171b 208 Pfam PF00072 Response regulator receiver domain 16 125 2.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS11305 64d8879e506a3031a54772088391171b 208 Gene3D G3DSA:1.10.10.10 158 198 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11305 64d8879e506a3031a54772088391171b 208 SMART SM00448 14 125 2.1E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS11305 64d8879e506a3031a54772088391171b 208 Pfam PF03861 ANTAR domain 144 195 4.1E-19 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS11305 64d8879e506a3031a54772088391171b 208 SMART SM01012 141 196 1.4E-22 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS11305 64d8879e506a3031a54772088391171b 208 Gene3D G3DSA:3.40.50.2300 2 157 2.3E-36 T 29-03-2018 MSG_RS11305 64d8879e506a3031a54772088391171b 208 SUPERFAMILY SSF52172 9 196 1.08E-57 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS05480 0e975301964dee462910b68183556b8c 148 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 25 132 3.5E-22 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05480 0e975301964dee462910b68183556b8c 148 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 29 137 5.2E-27 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05480 0e975301964dee462910b68183556b8c 148 SUPERFAMILY SSF81343 25 138 2.62E-25 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05480 0e975301964dee462910b68183556b8c 148 Gene3D G3DSA:1.20.1300.10 15 144 1.6E-24 T 29-03-2018 MSG_RS09485 bad97a066b76686b5528c8896302fb13 363 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 6 288 2.5E-77 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS09485 bad97a066b76686b5528c8896302fb13 363 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 363 79.777 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS09485 bad97a066b76686b5528c8896302fb13 363 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 7 283 2.1E-46 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS09485 bad97a066b76686b5528c8896302fb13 363 SUPERFAMILY SSF55931 2 359 1.57E-86 T 29-03-2018 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 317 7.6E-86 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 Gene3D G3DSA:3.40.718.10 1 336 3.2E-109 T 29-03-2018 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 336 60.54 T 29-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 231 250 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 SMART SM01329 2 332 6.5E-162 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MSG_RS07790 e0683f04440770b8b0ebec8dd6c1d330 336 SUPERFAMILY SSF53659 2 336 2.3E-109 T 29-03-2018 MSG_RS24175 50369457329aaf4dd177cae4b141b9c8 346 SMART SM01110 80 329 3.2E-57 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS24175 50369457329aaf4dd177cae4b141b9c8 346 SUPERFAMILY SSF53474 81 285 2.08E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24175 50369457329aaf4dd177cae4b141b9c8 346 Gene3D G3DSA:3.40.50.1820 77 336 2.7E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24175 50369457329aaf4dd177cae4b141b9c8 346 Pfam PF01083 Cutinase 119 285 9.1E-15 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 PRINTS PR01438 Universal stress protein signature 159 177 4.6E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 PRINTS PR01438 Universal stress protein signature 253 265 4.6E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 PRINTS PR01438 Universal stress protein signature 270 292 4.6E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 Gene3D G3DSA:3.40.50.620 153 294 2.1E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 Gene3D G3DSA:3.40.50.620 2 148 1.9E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 SUPERFAMILY SSF52402 10 153 3.01E-30 T 29-03-2018 MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 SUPERFAMILY SSF52402 161 293 2.6E-28 T 29-03-2018 MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 Pfam PF00582 Universal stress protein family 162 292 1.7E-24 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS14325 3a9aa61a4c5f508403af3400a60c84b4 294 Pfam PF00582 Universal stress protein family 10 148 1.9E-25 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS10940 d5549ba8eb99065a3ac68c04d1992b83 188 Pfam PF08241 Methyltransferase domain 39 133 1.9E-15 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS10940 d5549ba8eb99065a3ac68c04d1992b83 188 SMART SM00650 28 145 0.0019 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MSG_RS10940 d5549ba8eb99065a3ac68c04d1992b83 188 Gene3D G3DSA:3.40.50.150 2 187 1.4E-26 T 29-03-2018 MSG_RS10940 d5549ba8eb99065a3ac68c04d1992b83 188 SUPERFAMILY SSF53335 26 175 1.86E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS09005 ecc165cd69aaa6de4b31c24efe0769a5 135 Pfam PF11298 Protein of unknown function (DUF3099) 17 88 4.7E-29 T 29-03-2018 IPR021449 Protein of unknown function DUF3099 MSG_RS08695 6d522323ccc070c9e3d6b97dedfa52ee 151 Pfam PF03358 NADPH-dependent FMN reductase 49 126 5.9E-6 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MSG_RS08695 6d522323ccc070c9e3d6b97dedfa52ee 151 Gene3D G3DSA:3.40.50.360 1 151 7.2E-17 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS08695 6d522323ccc070c9e3d6b97dedfa52ee 151 SUPERFAMILY SSF52218 4 149 1.77E-24 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS12775 ad0639da4976ca1036bf9ae0e65542b2 167 SUPERFAMILY SSF54593 10 138 6.48E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS12775 ad0639da4976ca1036bf9ae0e65542b2 167 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 134 1.7E-22 T 29-03-2018 MSG_RS12775 ad0639da4976ca1036bf9ae0e65542b2 167 Gene3D G3DSA:3.10.180.10 2 161 5.3E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS11930 468ccfd44ce47008e88ef981bc37c1e6 69 Pfam PF03621 MbtH-like protein 3 53 5.1E-27 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS11930 468ccfd44ce47008e88ef981bc37c1e6 69 Gene3D G3DSA:3.90.820.10 3 69 1.7E-33 T 29-03-2018 MSG_RS11930 468ccfd44ce47008e88ef981bc37c1e6 69 SUPERFAMILY SSF160582 3 67 7.85E-29 T 29-03-2018 MSG_RS11930 468ccfd44ce47008e88ef981bc37c1e6 69 SMART SM00923 4 54 1.5E-29 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS16880 c7f0e844b435ad2fa0b3fc486bda1061 272 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 7 266 1.3E-110 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MSG_RS16880 c7f0e844b435ad2fa0b3fc486bda1061 272 Gene3D G3DSA:1.10.3720.10 8 272 1.8E-38 T 29-03-2018 MSG_RS16880 c7f0e844b435ad2fa0b3fc486bda1061 272 SUPERFAMILY SSF161098 6 258 1.27E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16880 c7f0e844b435ad2fa0b3fc486bda1061 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 261 1.1E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16880 c7f0e844b435ad2fa0b3fc486bda1061 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 13 264 3.3E-104 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 183 8.3E-4 T 29-03-2018 MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 Gene3D G3DSA:3.40.50.720 2 275 2.1E-64 T 29-03-2018 MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 Pfam PF00106 short chain dehydrogenase 5 186 6.2E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 SUPERFAMILY SSF51735 3 236 9.01E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 5.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07230 1f24af9eba87faaab569f7264b66a9d5 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 5.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 SMART SM00849 101 324 4.7E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 SUPERFAMILY SSF55718 509 626 5.06E-20 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 Gene3D G3DSA:3.60.15.10 75 377 3.1E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 Gene3D G3DSA:3.30.1050.10 503 626 4.7E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 Pfam PF14863 Alkyl sulfatase dimerisation 361 499 8.1E-59 T 29-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 Pfam PF00753 Metallo-beta-lactamase superfamily 97 324 1.6E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 SUPERFAMILY SSF56281 19 501 2.66E-146 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23885 d5064aa6dbd6e46d2829bcb7be862c94 626 Pfam PF14864 Alkyl sulfatase C-terminal 508 626 3.1E-31 T 29-03-2018 IPR029229 Alkyl sulfatase, C-terminal MSG_RS22945 a71cf1ac3a89a11ea4ffd99508b09efd 233 SUPERFAMILY SSF53448 10 214 1.08E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS22945 a71cf1ac3a89a11ea4ffd99508b09efd 233 Gene3D G3DSA:3.90.550.10 2 229 1.8E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS22945 a71cf1ac3a89a11ea4ffd99508b09efd 233 Pfam PF00535 Glycosyl transferase family 2 12 137 1.6E-26 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS00805 a7f290584d03eceb44457379260fafaf 138 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 56 120 7.6E-22 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS00805 a7f290584d03eceb44457379260fafaf 138 Gene3D G3DSA:2.40.50.140 60 128 3.7E-20 T 29-03-2018 MSG_RS00805 a7f290584d03eceb44457379260fafaf 138 SUPERFAMILY SSF50249 6 126 1.58E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 602 2.8E-19 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 500 4.7E-62 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Gene3D G3DSA:3.40.50.720 272 501 2.9E-63 T 29-03-2018 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Gene3D G3DSA:1.10.1040.10 502 607 1.6E-14 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Gene3D G3DSA:3.90.226.10 3 271 2.1E-51 T 29-03-2018 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 201 2.7E-33 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 SUPERFAMILY SSF48179 628 712 2.13E-11 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 SUPERFAMILY SSF51735 319 501 2.19E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 SUPERFAMILY SSF48179 502 641 1.96E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 SUPERFAMILY SSF52096 2 304 3.69E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20950 9a9057b49b9cda35e50ac3010a6983e0 714 Gene3D G3DSA:1.10.1040.10 629 714 1.2E-10 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 SUPERFAMILY SSF46689 4 85 1.69E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 Gene3D G3DSA:1.10.357.10 60 224 8.9E-16 T 29-03-2018 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 8.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 SUPERFAMILY SSF48498 88 167 9.79E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS02090 ce8429cf2cc4da6219d9f4496e5c558d 233 Gene3D G3DSA:1.10.10.60 11 59 2.7E-16 T 29-03-2018 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 SUPERFAMILY SSF51905 188 303 3.45E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 SUPERFAMILY SSF51905 430 487 3.45E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 SUPERFAMILY SSF51905 4 158 3.45E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 SUPERFAMILY SSF56425 302 413 2.44E-19 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 Gene3D G3DSA:3.50.50.60 10 488 4.7E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12195 5d88262ed24522557f453271f035ed95 488 Pfam PF00890 FAD binding domain 23 463 1.2E-43 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS18060 65302256261756f0dbcae43509684b45 114 Pfam PF12823 Domain of unknown function (DUF3817) 24 103 5.7E-21 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MSG_RS18060 65302256261756f0dbcae43509684b45 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 24 102 9.3E-20 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 387 3.2E-145 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 SUPERFAMILY SSF53383 17 387 6.6E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 Gene3D G3DSA:3.40.640.10 12 258 7.1E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 PIRSF PIRSF001434 1 388 9.5E-143 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 Gene3D G3DSA:3.90.1150.10 260 388 6.8E-50 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS19635 90ec31dd2c26340e11edb788194d7697 388 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS10390 2dac65e67481471cf5145572ab7a5082 302 Pfam PF03668 P-loop ATPase protein family 18 302 2.2E-132 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MSG_RS10390 2dac65e67481471cf5145572ab7a5082 302 SUPERFAMILY SSF52540 20 170 3.13E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10390 2dac65e67481471cf5145572ab7a5082 302 Gene3D G3DSA:3.40.50.300 18 177 1.8E-10 T 29-03-2018 MSG_RS10390 2dac65e67481471cf5145572ab7a5082 302 PIRSF PIRSF005052 18 302 1.8E-116 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MSG_RS10390 2dac65e67481471cf5145572ab7a5082 302 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 18 301 40.681 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MSG_RS04865 021ed95f9be0e795758e0232fa4940da 274 ProSitePatterns PS00155 Cutinase, serine active site. 92 104 - T 29-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 MSG_RS04865 021ed95f9be0e795758e0232fa4940da 274 Pfam PF01083 Cutinase 21 202 4.3E-48 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS04865 021ed95f9be0e795758e0232fa4940da 274 SMART SM01110 19 203 3.3E-73 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS04865 021ed95f9be0e795758e0232fa4940da 274 Gene3D G3DSA:3.40.50.1820 6 206 3.1E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04865 021ed95f9be0e795758e0232fa4940da 274 SUPERFAMILY SSF53474 11 203 2.96E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08445 0225b14b01313c8dc92ea219ee52dae6 371 SUPERFAMILY SSF53649 36 370 4.49E-51 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS08445 0225b14b01313c8dc92ea219ee52dae6 371 Gene3D G3DSA:3.40.720.10 27 371 3.0E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS08445 0225b14b01313c8dc92ea219ee52dae6 371 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 38 359 2.5E-32 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Gene3D G3DSA:3.90.1150.10 633 787 1.2E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 565 749 2.8E-22 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 291 516 1.0E-49 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Gene3D G3DSA:3.90.100.10 805 919 7.0E-22 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Gene3D G3DSA:3.40.640.10 291 632 3.4E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 829 884 1.4E-4 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 SUPERFAMILY SSF53383 555 768 5.96E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS00610 d3b3d03074c9ae2e3c9e56ed0477ee3d 976 SUPERFAMILY SSF53383 291 513 5.96E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Pfam PF03475 3-alpha domain 172 212 1.4E-10 T 29-03-2018 IPR005163 3-alpha domain MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 SUPERFAMILY SSF50800 2 213 1.2E-61 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 PRINTS PR00409 Phthalate dioxygenase reductase family signature 257 267 6.9E-11 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 PRINTS PR00409 Phthalate dioxygenase reductase family signature 341 360 6.9E-11 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 PRINTS PR00409 Phthalate dioxygenase reductase family signature 319 333 6.9E-11 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 PRINTS PR00409 Phthalate dioxygenase reductase family signature 424 432 6.9E-11 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 SUPERFAMILY SSF54292 447 568 1.23E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 496 560 2.2E-5 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 SUPERFAMILY SSF52343 333 459 1.44E-30 T 29-03-2018 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Pfam PF00970 Oxidoreductase FAD-binding domain 237 332 4.6E-7 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Pfam PF03473 MOSC domain 52 161 6.0E-18 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 SUPERFAMILY SSF63380 229 332 1.29E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Gene3D G3DSA:3.10.20.30 455 568 2.0E-15 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Gene3D G3DSA:2.40.33.20 1 227 6.1E-47 T 29-03-2018 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Gene3D G3DSA:2.40.30.10 229 333 3.3E-23 T 29-03-2018 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Gene3D G3DSA:3.40.50.80 334 454 3.0E-23 T 29-03-2018 MSG_RS21840 f6b6d5b638ac4f8e1ea6df90837b0f4b 568 Pfam PF00175 Oxidoreductase NAD-binding domain 342 438 2.4E-8 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS19830 cd5c03f20b0f5f9877265d63f3e8d33f 317 SUPERFAMILY SSF53067 134 316 2.85E-36 T 29-03-2018 MSG_RS19830 cd5c03f20b0f5f9877265d63f3e8d33f 317 Gene3D G3DSA:3.30.420.40 1 121 2.9E-45 T 29-03-2018 MSG_RS19830 cd5c03f20b0f5f9877265d63f3e8d33f 317 SUPERFAMILY SSF53067 3 129 3.74E-31 T 29-03-2018 MSG_RS19830 cd5c03f20b0f5f9877265d63f3e8d33f 317 Pfam PF02541 Ppx/GppA phosphatase family 17 314 6.5E-79 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MSG_RS19830 cd5c03f20b0f5f9877265d63f3e8d33f 317 Gene3D G3DSA:3.30.420.150 122 315 3.2E-51 T 29-03-2018 MSG_RS20220 b29a06d092ac7a4e111d1a42417a0d8a 165 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 11 149 1.6E-29 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20220 b29a06d092ac7a4e111d1a42417a0d8a 165 Pfam PF00994 Probable molybdopterin binding domain 14 151 1.3E-23 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20220 b29a06d092ac7a4e111d1a42417a0d8a 165 SMART SM00852 12 156 9.3E-18 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20220 b29a06d092ac7a4e111d1a42417a0d8a 165 Gene3D G3DSA:3.40.980.10 8 164 2.3E-28 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20220 b29a06d092ac7a4e111d1a42417a0d8a 165 SUPERFAMILY SSF53218 11 161 8.11E-32 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 PIRSF PIRSF036625 2 228 7.2E-64 T 29-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 Gene3D G3DSA:3.30.450.40 8 173 2.3E-19 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 Gene3D G3DSA:1.10.10.10 174 225 1.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 SUPERFAMILY SSF55781 27 164 3.71E-18 T 29-03-2018 IPR029016 GAF domain-like MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 SMART SM01012 168 223 6.9E-19 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 SUPERFAMILY SSF52172 168 223 8.45E-8 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 Pfam PF03861 ANTAR domain 171 223 6.6E-18 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS12090 4a19ea598f74286739326e50efdb8288 228 Pfam PF13185 GAF domain 25 163 1.2E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 Gene3D G3DSA:3.30.200.20 1 92 9.0E-21 T 29-03-2018 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 Gene3D G3DSA:2.40.100.10 415 601 1.4E-28 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 SUPERFAMILY SSF50891 434 600 4.09E-26 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 Pfam PF00069 Protein kinase domain 2 206 8.4E-41 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 116 128 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 Gene3D G3DSA:1.10.510.10 93 273 5.0E-39 T 29-03-2018 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 436 599 8.5E-16 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 SMART SM00220 1 257 7.9E-44 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 2 25 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS09725 63707e3106dc8321f8c542fccd9e023c 601 SUPERFAMILY SSF56112 2 299 1.48E-67 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 SUPERFAMILY SSF48264 9 362 1.7E-71 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 Gene3D G3DSA:1.10.630.10 154 360 1.5E-38 T 29-03-2018 MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 302 311 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 Pfam PF00067 Cytochrome P450 135 225 3.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 Pfam PF00067 Cytochrome P450 236 328 4.5E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS15930 b26418053b5851a65679a7de91252eb5 374 Gene3D G3DSA:1.10.630.10 13 153 2.2E-11 T 29-03-2018 MSG_RS17005 5627221cf9bbcc3566e7381a067a5439 283 Gene3D G3DSA:3.40.50.1110 3 245 7.5E-23 T 29-03-2018 MSG_RS17005 5627221cf9bbcc3566e7381a067a5439 283 SUPERFAMILY SSF52266 7 91 2.66E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS17005 5627221cf9bbcc3566e7381a067a5439 283 SUPERFAMILY SSF52266 135 235 2.66E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 Pfam PF02416 mttA/Hcf106 family 5 50 1.6E-4 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 84 6.5E-21 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 4.4E-9 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 4.4E-9 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 4.4E-9 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MSG_RS18790 a6749cbb7d7a399e3aaa3debc370c113 134 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 133 13.696 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MSG_RS20810 d1cd25420540a40a4306b296380b607e 160 SUPERFAMILY SSF53218 6 153 2.49E-36 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20810 d1cd25420540a40a4306b296380b607e 160 SMART SM00852 7 149 1.9E-15 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20810 d1cd25420540a40a4306b296380b607e 160 Pfam PF00994 Probable molybdopterin binding domain 8 147 7.0E-24 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20810 d1cd25420540a40a4306b296380b607e 160 Gene3D G3DSA:3.40.980.10 2 160 7.9E-35 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS20810 d1cd25420540a40a4306b296380b607e 160 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 142 8.4E-32 T 29-03-2018 IPR001453 MoaB/Mog domain MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 SUPERFAMILY SSF52788 3 152 2.09E-44 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 SMART SM00226 5 152 7.8E-55 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 5.9E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 5.9E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 5.9E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 50 66 5.9E-22 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 Gene3D G3DSA:3.40.50.2300 1 161 1.1E-46 T 29-03-2018 MSG_RS15580 d7ce0b3f665c94559587c7251c69048b 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 148 4.2E-43 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS02345 f72d9306db99c7c18da010866efaa706 544 Pfam PF00823 PPE family 8 164 3.1E-62 T 29-03-2018 IPR000030 PPE family MSG_RS02345 f72d9306db99c7c18da010866efaa706 544 SUPERFAMILY SSF140459 5 177 5.75E-64 T 29-03-2018 MSG_RS02345 f72d9306db99c7c18da010866efaa706 544 Gene3D G3DSA:1.10.287.1060 24 109 7.1E-7 T 29-03-2018 MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 Pfam PF05103 DivIVA protein 3 61 4.5E-12 T 29-03-2018 IPR007793 DivIVA family MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 SUPERFAMILY SSF58113 112 240 4.97E-6 T 29-03-2018 MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 Gene3D G3DSA:1.20.5.620 133 152 0.0027 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 Gene3D G3DSA:1.20.5.620 107 132 0.0063 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 Gene3D G3DSA:1.20.5.620 153 214 0.027 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS15050 0b40887c3c6a2b3e5813f83aa75768ba 263 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 1.1E-14 T 29-03-2018 IPR019933 DivIVA domain MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Pfam PF07497 Rho termination factor, RNA-binding domain 246 322 1.7E-27 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Pfam PF07498 Rho termination factor, N-terminal domain 37 73 7.9E-10 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 354 558 1.7E-25 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 TIGRFAM TIGR00767 rho: transcription termination factor Rho 35 613 2.0E-211 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Gene3D G3DSA:2.40.50.140 245 306 9.4E-29 T 29-03-2018 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SMART SM00382 365 550 4.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SUPERFAMILY SSF50249 247 321 4.11E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SUPERFAMILY SSF52540 316 565 1.05E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SUPERFAMILY SSF68912 37 76 5.49E-5 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Hamap MF_01884 Transcription termination factor Rho [rho]. 239 614 198.227 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Gene3D G3DSA:1.10.720.10 36 72 2.4E-11 T 29-03-2018 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 Gene3D G3DSA:3.40.50.300 307 564 2.2E-53 T 29-03-2018 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SMART SM00959 36 78 7.2E-12 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MSG_RS18310 cfd7bac27211b3d0cd52ed7eb7032bf1 622 SMART SM00357 247 308 4.4E-9 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 Pfam PF04542 Sigma-70 region 2 84 150 4.6E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 Gene3D G3DSA:1.10.1740.10 75 147 1.8E-23 T 29-03-2018 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 Gene3D G3DSA:1.10.10.10 148 240 2.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 SUPERFAMILY SSF88946 80 168 2.2E-25 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 SUPERFAMILY SSF88659 160 239 2.06E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 81 237 1.8E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS18805 d66cc3cd999b92144221cd89ebbdf885 253 Pfam PF08281 Sigma-70, region 4 183 233 8.1E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 24 446 2.0E-211 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 PIRSF PIRSF000521 139 449 4.5E-35 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 PIRSF PIRSF000521 3 145 1.1E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 SUPERFAMILY SSF53383 38 448 1.03E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 299 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 Gene3D G3DSA:3.40.640.10 204 331 2.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 Gene3D G3DSA:3.90.1150.10 16 174 1.3E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 Gene3D G3DSA:3.90.1150.10 332 449 1.7E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS09690 8b11822877fcc972987adc845294c7d5 449 Pfam PF00202 Aminotransferase class-III 37 443 5.3E-132 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS14490 ebcf579e976fec7afb90a7a58e5cfa61 162 Pfam PF01202 Shikimate kinase 5 110 3.7E-12 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MSG_RS14490 ebcf579e976fec7afb90a7a58e5cfa61 162 Gene3D G3DSA:3.40.50.300 1 154 7.5E-24 T 29-03-2018 MSG_RS14490 ebcf579e976fec7afb90a7a58e5cfa61 162 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 1 147 9.7E-51 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MSG_RS14490 ebcf579e976fec7afb90a7a58e5cfa61 162 SUPERFAMILY SSF52540 1 147 4.65E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12720 c379d3f8b33957f1f977417e7b986f1e 111 Pfam PF05305 Protein of unknown function (DUF732) 7 98 1.0E-28 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS13290 1410f9a2fd99f456982652fca4506f1b 103 Gene3D G3DSA:3.30.70.930 2 103 3.3E-32 T 29-03-2018 IPR029756 MTH1187/YkoF-like MSG_RS13290 1410f9a2fd99f456982652fca4506f1b 103 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 97 2.2E-17 T 29-03-2018 IPR002767 Thiamine-binding protein MSG_RS13290 1410f9a2fd99f456982652fca4506f1b 103 Pfam PF01910 Thiamine-binding protein 5 95 1.8E-29 T 29-03-2018 IPR002767 Thiamine-binding protein MSG_RS13290 1410f9a2fd99f456982652fca4506f1b 103 SUPERFAMILY SSF89957 3 98 4.84E-28 T 29-03-2018 IPR029756 MTH1187/YkoF-like MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.8E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 Gene3D G3DSA:1.10.1660.10 56 126 6.4E-9 T 29-03-2018 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 Pfam PF13411 MerR HTH family regulatory protein 1 67 8.4E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 SUPERFAMILY SSF46955 1 111 1.68E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 Gene3D G3DSA:1.10.1660.10 1 55 1.1E-20 T 29-03-2018 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 SMART SM00422 1 69 4.3E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07355 706a7ade4be0709f2c0dfe3f21a2f36f 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 Gene3D G3DSA:1.10.260.40 53 157 1.0E-12 T 29-03-2018 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 Gene3D G3DSA:1.10.10.60 11 52 4.9E-16 T 29-03-2018 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 73 2.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 SUPERFAMILY SSF46689 22 82 4.73E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 4.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07330 053b55a59aaaab174e2ccf438619af95 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 4.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17205 f6ea75e3084de76c3c33b4ba6bf36f57 420 Gene3D G3DSA:1.20.1250.20 205 412 1.0E-22 T 29-03-2018 MSG_RS17205 f6ea75e3084de76c3c33b4ba6bf36f57 420 ProSitePatterns PS00216 Sugar transport proteins signature 1. 274 290 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS17205 f6ea75e3084de76c3c33b4ba6bf36f57 420 SUPERFAMILY SSF103473 14 400 1.57E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS17205 f6ea75e3084de76c3c33b4ba6bf36f57 420 Pfam PF07690 Major Facilitator Superfamily 15 337 6.1E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS17205 f6ea75e3084de76c3c33b4ba6bf36f57 420 Gene3D G3DSA:1.20.1250.20 10 187 1.9E-18 T 29-03-2018 MSG_RS14710 5f6fa61d45deebc96593255089ee161e 257 Pfam PF14230 Domain of unknown function (DUF4333) 167 249 4.7E-24 T 29-03-2018 IPR025637 Domain of unknown function DUF4333 MSG_RS01110 2c246061911099683fd36caf3b082771 538 SUPERFAMILY SSF56801 22 530 1.96E-115 T 29-03-2018 MSG_RS01110 2c246061911099683fd36caf3b082771 538 Pfam PF00501 AMP-binding enzyme 31 435 2.0E-73 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS01110 2c246061911099683fd36caf3b082771 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 520 1.0E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS01110 2c246061911099683fd36caf3b082771 538 Gene3D G3DSA:3.30.300.30 430 538 6.0E-23 T 29-03-2018 MSG_RS01110 2c246061911099683fd36caf3b082771 538 Gene3D G3DSA:2.30.38.10 350 429 9.4E-11 T 29-03-2018 MSG_RS01110 2c246061911099683fd36caf3b082771 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01110 2c246061911099683fd36caf3b082771 538 Gene3D G3DSA:3.40.50.980 22 194 8.2E-33 T 29-03-2018 MSG_RS01110 2c246061911099683fd36caf3b082771 538 Gene3D G3DSA:3.40.50.980 195 349 9.6E-41 T 29-03-2018 MSG_RS00605 38a5927e4c1ea828b6f4b4d0eeac6e95 262 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 12 254 5.8E-43 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MSG_RS00605 38a5927e4c1ea828b6f4b4d0eeac6e95 262 SUPERFAMILY SSF51197 9 258 1.88E-62 T 29-03-2018 MSG_RS00605 38a5927e4c1ea828b6f4b4d0eeac6e95 262 Gene3D G3DSA:3.60.130.10 7 261 2.7E-49 T 29-03-2018 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Pfam PF04545 Sigma-70, region 4 254 307 2.4E-18 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 SUPERFAMILY SSF88659 159 232 1.44E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Pfam PF04539 Sigma-70 region 3 165 241 1.4E-25 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 279 305 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 SUPERFAMILY SSF88946 21 156 1.07E-50 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 SUPERFAMILY SSF88659 216 314 2.43E-25 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 82 307 3.1E-36 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Pfam PF04542 Sigma-70 region 2 86 155 7.2E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Gene3D G3DSA:1.10.601.10 2 155 2.8E-66 T 29-03-2018 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 110 123 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Gene3D G3DSA:1.10.10.10 249 319 4.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Pfam PF00140 Sigma-70 factor, region 1.2 21 54 6.7E-12 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 Gene3D G3DSA:1.10.10.10 156 206 3.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 PRINTS PR00046 Major sigma-70 factor signature 279 294 3.8E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 PRINTS PR00046 Major sigma-70 factor signature 258 270 3.8E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 PRINTS PR00046 Major sigma-70 factor signature 110 123 3.8E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 PRINTS PR00046 Major sigma-70 factor signature 134 142 3.8E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS09000 d9313b15d2627917395f44f3ae75022b 319 PRINTS PR00046 Major sigma-70 factor signature 294 305 3.8E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS16790 3ea10e9b66c54940c77a3959c15245a9 245 Pfam PF00975 Thioesterase domain 23 241 1.4E-42 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MSG_RS16790 3ea10e9b66c54940c77a3959c15245a9 245 Gene3D G3DSA:3.40.50.1820 9 243 1.9E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16790 3ea10e9b66c54940c77a3959c15245a9 245 SUPERFAMILY SSF53474 3 242 3.95E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14580 449ce1929d70764f5e2e3e19df719817 126 Gene3D G3DSA:2.30.110.10 4 112 6.2E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS14580 449ce1929d70764f5e2e3e19df719817 126 SUPERFAMILY SSF50475 8 112 3.04E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS14580 449ce1929d70764f5e2e3e19df719817 126 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 85 4.6E-12 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS14580 449ce1929d70764f5e2e3e19df719817 126 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 125 3.5E-55 T 29-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 Gene3D G3DSA:1.10.1040.10 192 446 1.4E-104 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 SUPERFAMILY SSF51735 15 188 6.78E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 265 277 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 16 481 6.1E-214 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 190 480 3.1E-121 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 SMART SM01350 190 481 6.1E-201 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 78 107 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 131 156 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 15 38 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 179 207 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 368 390 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 261 288 1.5E-81 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 Gene3D G3DSA:3.40.50.720 12 191 5.1E-38 T 29-03-2018 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 SUPERFAMILY SSF48179 188 484 1.13E-115 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 185 3.5E-49 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 Gene3D G3DSA:1.20.5.320 447 489 8.1E-14 T 29-03-2018 MSG_RS12925 4ac53b601c4cdbb7068f8d1c7f7abecf 489 PIRSF PIRSF000109 9 489 1.2E-199 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS11740 70977eb78536d674e0e23c437751d914 354 SUPERFAMILY SSF54506 158 337 2.62E-41 T 29-03-2018 MSG_RS11740 70977eb78536d674e0e23c437751d914 354 Gene3D G3DSA:3.10.310.10 1 162 5.4E-46 T 29-03-2018 MSG_RS11740 70977eb78536d674e0e23c437751d914 354 SUPERFAMILY SSF54506 2 148 1.1E-40 T 29-03-2018 MSG_RS11740 70977eb78536d674e0e23c437751d914 354 Gene3D G3DSA:3.10.310.10 163 317 1.5E-39 T 29-03-2018 MSG_RS11740 70977eb78536d674e0e23c437751d914 354 Pfam PF04303 PrpF protein 2 336 5.6E-77 T 29-03-2018 IPR007400 PrpF protein MSG_RS12175 e25660b831c5f944ab086ecbad6db8ef 378 SUPERFAMILY SSF50022 19 133 1.96E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12175 e25660b831c5f944ab086ecbad6db8ef 378 Pfam PF00355 Rieske [2Fe-2S] domain 26 110 5.8E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12175 e25660b831c5f944ab086ecbad6db8ef 378 Gene3D G3DSA:3.90.380.10 134 345 5.1E-32 T 29-03-2018 MSG_RS12175 e25660b831c5f944ab086ecbad6db8ef 378 Gene3D G3DSA:2.102.10.10 18 133 1.2E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12175 e25660b831c5f944ab086ecbad6db8ef 378 SUPERFAMILY SSF55961 124 363 1.35E-34 T 29-03-2018 MSG_RS18510 04c22fff20ff8126f14de6e11ab84199 424 SUPERFAMILY SSF53474 29 350 1.82E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18510 04c22fff20ff8126f14de6e11ab84199 424 Pfam PF00561 alpha/beta hydrolase fold 49 169 4.7E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS18510 04c22fff20ff8126f14de6e11ab84199 424 Gene3D G3DSA:3.40.50.1820 25 367 2.8E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00500 eea27036399059dcbccff92d0931d1a8 181 Pfam PF13577 SnoaL-like domain 35 158 6.3E-23 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS00500 eea27036399059dcbccff92d0931d1a8 181 Gene3D G3DSA:3.10.450.50 22 175 2.9E-30 T 29-03-2018 MSG_RS00500 eea27036399059dcbccff92d0931d1a8 181 SUPERFAMILY SSF54427 26 164 5.61E-30 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 5.3E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 Gene3D G3DSA:1.10.357.10 3 202 4.0E-35 T 29-03-2018 MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 SUPERFAMILY SSF46689 5 83 1.33E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00880 94be7c0380c9c7776575f2a67e923634 202 SUPERFAMILY SSF48498 88 199 2.52E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS24705 b6fad36af84ee5047f6f364cb5e21ba1 115 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 18 86 4.6E-27 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MSG_RS24705 b6fad36af84ee5047f6f364cb5e21ba1 115 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 28 81 1.0E-23 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MSG_RS24705 b6fad36af84ee5047f6f364cb5e21ba1 115 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 14 82 23.601 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MSG_RS24705 b6fad36af84ee5047f6f364cb5e21ba1 115 Pfam PF01809 Haemolytic domain 18 81 5.5E-27 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MSG_RS24705 b6fad36af84ee5047f6f364cb5e21ba1 115 SMART SM01234 14 81 4.9E-35 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MSG_RS04135 0eaf7307c7cabb0e51f8302936d942e5 293 Gene3D G3DSA:3.40.50.150 9 293 1.3E-53 T 29-03-2018 MSG_RS04135 0eaf7307c7cabb0e51f8302936d942e5 293 Pfam PF02353 Mycolic acid cyclopropane synthetase 12 289 1.0E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04135 0eaf7307c7cabb0e51f8302936d942e5 293 SUPERFAMILY SSF53335 19 293 2.01E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04135 0eaf7307c7cabb0e51f8302936d942e5 293 PIRSF PIRSF003085 3 293 2.2E-103 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS06200 604a3c1a0969c77232d8d52df98ede72 160 Gene3D G3DSA:3.40.630.30 2 87 9.4E-22 T 29-03-2018 MSG_RS06200 604a3c1a0969c77232d8d52df98ede72 160 Pfam PF00583 Acetyltransferase (GNAT) family 40 132 2.0E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS06200 604a3c1a0969c77232d8d52df98ede72 160 SUPERFAMILY SSF55729 4 150 1.65E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS06200 604a3c1a0969c77232d8d52df98ede72 160 Gene3D G3DSA:3.40.630.30 88 150 5.1E-15 T 29-03-2018 MSG_RS21200 4305c6970117a5df96eb1d809d2237a4 381 SUPERFAMILY SSF51556 75 367 2.58E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21200 4305c6970117a5df96eb1d809d2237a4 381 SUPERFAMILY SSF51556 19 47 2.58E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21200 4305c6970117a5df96eb1d809d2237a4 381 Gene3D G3DSA:3.20.20.140 14 370 6.7E-33 T 29-03-2018 MSG_RS21200 4305c6970117a5df96eb1d809d2237a4 381 Pfam PF04909 Amidohydrolase 107 367 3.7E-26 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 SUPERFAMILY SSF48264 2 391 3.67E-67 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 Pfam PF00067 Cytochrome P450 270 362 2.5E-13 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 Gene3D G3DSA:1.10.630.10 1 391 2.0E-47 T 29-03-2018 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 284 311 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 342 353 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 267 278 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 333 342 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 126 142 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 312 327 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01660 207c2dce1ffb7fcbceaa4f1085b0080a 391 PRINTS PR00359 B-class P450 signature 181 203 6.1E-22 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS07400 d6a56b99300659249b4e84d049203f01 543 Gene3D G3DSA:3.50.50.60 14 543 6.0E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07400 d6a56b99300659249b4e84d049203f01 543 Pfam PF13450 NAD(P)-binding Rossmann-like domain 26 75 1.6E-9 T 29-03-2018 MSG_RS07400 d6a56b99300659249b4e84d049203f01 543 Pfam PF01593 Flavin containing amine oxidoreductase 223 516 7.2E-10 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS07400 d6a56b99300659249b4e84d049203f01 543 SUPERFAMILY SSF51905 19 348 1.7E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07400 d6a56b99300659249b4e84d049203f01 543 SUPERFAMILY SSF51905 501 520 1.7E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 ProSitePatterns PS00517 Ribonuclease III family signature. 40 48 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 SUPERFAMILY SSF69065 8 152 5.06E-42 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 Pfam PF00035 Double-stranded RNA binding motif 161 225 1.1E-15 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 223 28.726 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 Gene3D G3DSA:1.10.1520.10 15 153 8.7E-37 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 Pfam PF14622 Ribonuclease-III-like 17 143 6.8E-36 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 SMART SM00358 161 227 7.9E-23 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 SUPERFAMILY SSF54768 115 229 1.52E-26 T 29-03-2018 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 17 225 2.8E-69 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 SMART SM00535 18 154 1.0E-53 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MSG_RS08075 88976b29f1b76d880682d29bc0756b86 237 Gene3D G3DSA:3.30.160.20 154 222 2.2E-20 T 29-03-2018 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.5E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 SUPERFAMILY SSF50249 1 66 1.39E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 PIRSF PIRSF002599 1 67 3.0E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 PRINTS PR00050 Cold shock protein signature 40 58 1.6E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 SMART SM00357 3 67 1.2E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MSG_RS11425 c06d191ab678e53419c5d287da6c9543 67 Gene3D G3DSA:2.40.50.140 1 67 3.1E-29 T 29-03-2018 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Gene3D G3DSA:3.30.310.50 443 542 1.4E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 SUPERFAMILY SSF55957 430 542 1.12E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 SUPERFAMILY SSF53738 303 445 2.83E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 476 536 1.0E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Gene3D G3DSA:3.40.120.10 26 214 1.2E-45 T 29-03-2018 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 2 542 2.2E-300 T 29-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Gene3D G3DSA:3.40.120.10 215 330 5.2E-21 T 29-03-2018 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 207 312 5.1E-10 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 39 180 8.2E-38 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Gene3D G3DSA:3.40.120.10 331 442 9.1E-24 T 29-03-2018 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 318 438 8.6E-26 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS07080 1b08ceeda54366bd44a4d5ce5b75b67a 542 SUPERFAMILY SSF53738 25 232 5.42E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 SUPERFAMILY SSF48008 121 260 9.15E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 SUPERFAMILY SSF46785 27 100 9.09E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 Gene3D G3DSA:1.20.120.530 105 267 1.6E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 90 7.9E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 Pfam PF07729 FCD domain 125 253 2.2E-19 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 Gene3D G3DSA:1.10.10.10 18 98 5.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 SMART SM00895 121 254 1.2E-16 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 8.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 8.2E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 SMART SM00345 35 96 1.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17710 8cf6c9f28418661338fcb94a0742b5d9 288 SMART SM00418 30 113 0.0082 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 113 9.4E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Gene3D G3DSA:2.40.110.10 114 212 7.0E-32 T 29-03-2018 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Gene3D G3DSA:1.10.540.10 1 113 5.2E-20 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 SUPERFAMILY SSF47203 225 363 7.8E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 211 4.4E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 SUPERFAMILY SSF56645 2 238 7.07E-64 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 361 3.8E-9 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21520 fda21f50796a7d20895224c55a256b3e 363 Gene3D G3DSA:1.20.140.10 213 363 6.9E-20 T 29-03-2018 MSG_RS20120 def0e57b19b6dac4d2b34b715218d4a2 255 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 62 232 2.9E-50 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MSG_RS20120 def0e57b19b6dac4d2b34b715218d4a2 255 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 232 4.4E-36 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 165 180 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 98 109 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 296 307 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 148 164 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 215 237 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 314 341 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 342 357 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 372 383 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 PRINTS PR00359 B-class P450 signature 363 372 7.9E-49 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 Gene3D G3DSA:1.10.630.10 2 422 2.8E-68 T 29-03-2018 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 Pfam PF00067 Cytochrome P450 296 392 5.6E-18 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS04025 d3310c7cbac4b75bccaac68dd5427eee 426 SUPERFAMILY SSF48264 13 420 1.96E-80 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 SUPERFAMILY SSF52540 5 199 1.43E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 3 443 40.934 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 SUPERFAMILY SSF52317 256 451 1.16E-29 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 256 438 2.1E-24 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 Gene3D G3DSA:3.40.50.880 174 402 8.8E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 453 1.3E-115 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 191 8.1E-20 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS08490 955bf12fa4283c9247dc45a77a7abda7 461 Gene3D G3DSA:3.40.50.300 1 173 3.2E-37 T 29-03-2018 MSG_RS23155 9044b63b6c861af9d089b16a0d392e30 339 Pfam PF02374 Anion-transporting ATPase 197 244 6.1E-5 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MSG_RS23155 9044b63b6c861af9d089b16a0d392e30 339 Pfam PF02374 Anion-transporting ATPase 22 180 2.5E-17 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MSG_RS23155 9044b63b6c861af9d089b16a0d392e30 339 SUPERFAMILY SSF52540 21 243 4.68E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23155 9044b63b6c861af9d089b16a0d392e30 339 Gene3D G3DSA:3.40.50.300 183 339 5.1E-20 T 29-03-2018 MSG_RS23155 9044b63b6c861af9d089b16a0d392e30 339 Gene3D G3DSA:3.40.50.300 15 182 6.2E-26 T 29-03-2018 MSG_RS16075 c1b3b6395f856a9d81e587c16da9a289 351 SUPERFAMILY SSF51556 11 315 1.85E-69 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS16075 c1b3b6395f856a9d81e587c16da9a289 351 Pfam PF04909 Amidohydrolase 12 315 9.1E-39 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS16075 c1b3b6395f856a9d81e587c16da9a289 351 Gene3D G3DSA:3.20.20.140 12 343 1.2E-47 T 29-03-2018 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 SUPERFAMILY SSF54506 149 280 4.91E-28 T 29-03-2018 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 Gene3D G3DSA:3.10.310.10 1 141 2.6E-39 T 29-03-2018 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 2 281 4.6E-73 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 Gene3D G3DSA:3.10.310.10 142 269 5.5E-39 T 29-03-2018 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 SUPERFAMILY SSF54506 2 139 2.49E-29 T 29-03-2018 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 Pfam PF01678 Diaminopimelate epimerase 3 141 3.3E-35 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 Pfam PF01678 Diaminopimelate epimerase 158 274 7.0E-21 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MSG_RS08925 d9b3db8f6c21841386191b367ef32dd8 289 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 282 28.408 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 SUPERFAMILY SSF52540 162 354 1.62E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Pfam PF01018 GTP1/OBG 5 158 7.0E-51 T 29-03-2018 IPR006169 GTP1/OBG domain MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Gene3D G3DSA:3.40.50.300 159 347 7.5E-28 T 29-03-2018 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Pfam PF09269 Domain of unknown function (DUF1967) 366 434 7.6E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 366 435 2.5E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 SUPERFAMILY SSF82051 4 157 8.37E-47 T 29-03-2018 IPR006169 GTP1/OBG domain MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Pfam PF01926 50S ribosome-binding GTPase 162 293 2.8E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 339 3.4E-122 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 SUPERFAMILY SSF102741 364 436 1.57E-21 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Hamap MF_01454 GTPase Obg [obg]. 3 340 43.637 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 4.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 4.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.1E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS17140 8285997c4606053c811b9b47d422f615 480 Gene3D G3DSA:2.70.210.12 3 156 7.9E-51 T 29-03-2018 IPR006169 GTP1/OBG domain MSG_RS03445 1802565385770668798e65d798cd3b03 249 Pfam PF00106 short chain dehydrogenase 10 186 2.0E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 Gene3D G3DSA:3.40.50.720 8 234 9.6E-49 T 29-03-2018 MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 SUPERFAMILY SSF51735 6 227 8.72E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03445 1802565385770668798e65d798cd3b03 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.9E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS16050 155f00c627e3ce9e93c96433ab1b2274 324 Gene3D G3DSA:3.20.20.30 4 321 2.3E-51 T 29-03-2018 MSG_RS16050 155f00c627e3ce9e93c96433ab1b2274 324 SUPERFAMILY SSF51679 16 321 7.2E-47 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS16050 155f00c627e3ce9e93c96433ab1b2274 324 Pfam PF00296 Luciferase-like monooxygenase 19 252 2.6E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 PIRSF PIRSF000429 168 387 5.1E-12 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 PIRSF PIRSF000429 7 130 6.1E-9 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 SUPERFAMILY SSF53901 14 229 4.61E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 Gene3D G3DSA:3.40.47.10 217 386 4.0E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 Gene3D G3DSA:3.40.47.10 5 216 6.7E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22400 bf1dd5d7180f5575f58c1693c891a434 397 SUPERFAMILY SSF53901 236 377 8.06E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16010 fedd84e5ed64b04c2e816d7eabc0da0c 290 SUPERFAMILY SSF53167 201 256 6.68E-25 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS16010 fedd84e5ed64b04c2e816d7eabc0da0c 290 SUPERFAMILY SSF53167 16 135 6.68E-25 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS16010 fedd84e5ed64b04c2e816d7eabc0da0c 290 Gene3D G3DSA:3.40.50.1580 5 288 2.4E-30 T 29-03-2018 MSG_RS16010 fedd84e5ed64b04c2e816d7eabc0da0c 290 Pfam PF01048 Phosphorylase superfamily 17 287 3.0E-22 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MSG_RS11280 77ce1b5b6d2cf36768ceea4eb8ae6efa 346 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 219 3.5E-61 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MSG_RS11280 77ce1b5b6d2cf36768ceea4eb8ae6efa 346 PIRSF PIRSF000267 2 339 1.7E-100 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MSG_RS11280 77ce1b5b6d2cf36768ceea4eb8ae6efa 346 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 326 5.4E-101 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MSG_RS13770 58e987e849c53aaa35f297dc7b209f79 196 Pfam PF07366 SnoaL-like polyketide cyclase 58 175 1.2E-16 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS13770 58e987e849c53aaa35f297dc7b209f79 196 Gene3D G3DSA:3.10.450.50 1 37 0.028 T 29-03-2018 MSG_RS13770 58e987e849c53aaa35f297dc7b209f79 196 SUPERFAMILY SSF54427 52 175 2.12E-25 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS13770 58e987e849c53aaa35f297dc7b209f79 196 Gene3D G3DSA:3.10.450.50 38 181 3.7E-27 T 29-03-2018 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.091 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 SUPERFAMILY SSF48592 6 133 8.08E-74 T 29-03-2018 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 SUPERFAMILY SSF48592 404 518 8.08E-74 T 29-03-2018 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 PRINTS PR00298 60kDa chaperonin signature 348 373 2.6E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 PRINTS PR00298 60kDa chaperonin signature 26 52 2.6E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 PRINTS PR00298 60kDa chaperonin signature 266 289 2.6E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 PRINTS PR00298 60kDa chaperonin signature 82 109 2.6E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 PRINTS PR00298 60kDa chaperonin signature 396 417 2.6E-70 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 Gene3D G3DSA:1.10.560.10 1 200 3.6E-42 T 29-03-2018 IPR027413 GroEL-like equatorial domain MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 Gene3D G3DSA:3.50.7.10 201 371 1.7E-92 T 29-03-2018 IPR027409 GroEL-like apical domain MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 SUPERFAMILY SSF54849 137 200 4.12E-26 T 29-03-2018 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 6.1E-97 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 8.9E-251 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 Gene3D G3DSA:1.10.560.10 372 513 3.4E-24 T 29-03-2018 IPR027413 GroEL-like equatorial domain MSG_RS03220 ce301a31f6eccadcb529634c7d3ae881 541 SUPERFAMILY SSF52029 184 374 2.69E-81 T 29-03-2018 IPR027409 GroEL-like apical domain MSG_RS23210 c0e799f3bc83017acef7355d9c2edd37 224 Gene3D G3DSA:3.40.50.1000 72 215 6.7E-25 T 29-03-2018 IPR023214 HAD-like domain MSG_RS23210 c0e799f3bc83017acef7355d9c2edd37 224 Gene3D G3DSA:1.10.150.240 20 71 5.6E-21 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MSG_RS23210 c0e799f3bc83017acef7355d9c2edd37 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 2.4E-24 T 29-03-2018 IPR023214 HAD-like domain MSG_RS23210 c0e799f3bc83017acef7355d9c2edd37 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 177 5.8E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS23210 c0e799f3bc83017acef7355d9c2edd37 224 SUPERFAMILY SSF56784 3 212 2.03E-47 T 29-03-2018 IPR023214 HAD-like domain MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 Gene3D G3DSA:3.20.20.140 69 498 9.6E-59 T 29-03-2018 MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 Pfam PF07969 Amidohydrolase family 50 567 5.2E-57 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 SUPERFAMILY SSF51556 62 320 2.24E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 SUPERFAMILY SSF51556 376 514 2.24E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 Gene3D G3DSA:2.30.40.10 2 68 4.2E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 Gene3D G3DSA:2.30.40.10 499 580 2.2E-4 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 SUPERFAMILY SSF51338 514 576 4.63E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS00770 db59d89fb86f6ca7cfc2f1cb3ec2c8bd 586 SUPERFAMILY SSF51338 2 61 4.63E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.677 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.7E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.7E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.7E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 SUPERFAMILY SSF143034 2 62 8.5E-21 T 29-03-2018 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 Pfam PF01632 Ribosomal protein L35 2 62 2.7E-24 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS11455 c5f8e760df55902d9c370c8a9b9d87a5 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.6E-26 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MSG_RS09970 c3c613f8924aa28dade89c02044433ad 101 Pfam PF06249 Ethanolamine utilisation protein EutQ 4 92 3.5E-15 T 29-03-2018 IPR010424 Ethanolamine utilisation EutQ MSG_RS09970 c3c613f8924aa28dade89c02044433ad 101 Gene3D G3DSA:2.60.120.10 2 99 1.8E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS09970 c3c613f8924aa28dade89c02044433ad 101 SUPERFAMILY SSF51182 4 94 4.45E-15 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS15865 a5518c3613294803d5e310dea478f970 110 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 13 100 6.0E-9 T 29-03-2018 IPR020264 Uncharacterised protein family YidG MSG_RS15865 a5518c3613294803d5e310dea478f970 110 Pfam PF02656 Domain of unknown function (DUF202) 13 72 5.6E-8 T 29-03-2018 IPR003807 Domain of unknown function DUF202 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 Gene3D G3DSA:3.40.50.980 174 342 9.8E-25 T 29-03-2018 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 Gene3D G3DSA:3.30.300.30 460 567 1.8E-14 T 29-03-2018 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 Pfam PF00501 AMP-binding enzyme 13 466 3.3E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 SUPERFAMILY SSF56801 374 570 8.37E-90 T 29-03-2018 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 SUPERFAMILY SSF56801 7 346 8.37E-90 T 29-03-2018 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 Gene3D G3DSA:2.30.38.10 377 459 1.1E-19 T 29-03-2018 MSG_RS08005 21a400fd470b5adb00055af9f5bf9923 579 Gene3D G3DSA:3.40.50.980 4 173 5.4E-31 T 29-03-2018 MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 SUPERFAMILY SSF53254 1 198 9.85E-51 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 PIRSF PIRSF000709 1 182 1.3E-8 T 29-03-2018 MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 SMART SM00855 5 166 2.4E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 199 1.2E-48 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MSG_RS17010 c3980c8616e99cdcf89b033a0706c539 224 Gene3D G3DSA:3.40.50.1240 3 223 3.6E-49 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Gene3D G3DSA:1.20.140.10 228 385 6.8E-51 T 29-03-2018 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Gene3D G3DSA:2.40.110.10 128 227 3.6E-39 T 29-03-2018 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 1.7E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 2.5E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Gene3D G3DSA:1.10.540.10 2 127 9.0E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 3.5E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 SUPERFAMILY SSF47203 234 384 7.41E-49 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08935 13b29673961fa0e2b971c106ead362d9 386 SUPERFAMILY SSF56645 9 248 6.28E-85 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 SUPERFAMILY SSF51735 6 269 9.93E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 Gene3D G3DSA:3.40.50.720 44 272 1.4E-45 T 29-03-2018 MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 Gene3D G3DSA:3.40.50.720 2 43 1.2E-6 T 29-03-2018 MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 3.0E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 268 3.3E-39 T 29-03-2018 MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23675 8bfaedcfa0cfc3b3f51d12e9ffa693c7 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 SUPERFAMILY SSF55021 9 86 1.28E-8 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 2.4E-28 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Gene3D G3DSA:3.40.50.1000 241 386 1.8E-28 T 29-03-2018 IPR023214 HAD-like domain MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Pfam PF13740 ACT domain 9 64 7.3E-17 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Gene3D G3DSA:3.30.70.260 8 89 2.3E-11 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Gene3D G3DSA:3.30.70.260 96 179 3.5E-16 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 SUPERFAMILY SSF56784 181 388 3.47E-49 T 29-03-2018 IPR023214 HAD-like domain MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 168 386 4.3E-72 T 29-03-2018 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Gene3D G3DSA:1.10.150.210 194 240 1.4E-21 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 MSG_RS07460 13bca093ec0b476cdd363f1c4d4ade4c 411 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 9.8E-29 T 29-03-2018 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 SUPERFAMILY SSF51735 1 132 3.11E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 127 144 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 Gene3D G3DSA:3.40.50.720 1 121 9.9E-22 T 29-03-2018 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 243 28.733 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 105 1.0E-21 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 SUPERFAMILY SSF55347 106 214 1.11E-41 T 29-03-2018 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 108 233 6.9E-31 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 PIRSF PIRSF000161 1 245 6.0E-61 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 Gene3D G3DSA:3.30.360.10 122 211 1.4E-35 T 29-03-2018 MSG_RS08685 86b987970d77a5f46aa85ee62289e7b5 245 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 41 242 1.6E-55 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 SMART SM00418 28 108 3.2E-27 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 SUPERFAMILY SSF46785 18 106 9.35E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 Pfam PF01022 Bacterial regulatory protein, arsR family 35 82 2.9E-17 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 Gene3D G3DSA:1.10.10.10 13 109 3.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 1.4E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 80 95 1.4E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 1.4E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS23700 532813e8bb4e6fc9a34264f331a6f07b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 63 1.4E-21 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 SUPERFAMILY SSF51735 1 353 6.13E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 271 5.3E-45 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 Gene3D G3DSA:3.40.50.720 1 223 3.1E-31 T 29-03-2018 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 Gene3D G3DSA:3.90.25.10 224 361 3.2E-32 T 29-03-2018 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 PRINTS PR01713 Nucleotide sugar epimerase signature 272 287 5.5E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 PRINTS PR01713 Nucleotide sugar epimerase signature 311 328 5.5E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MSG_RS10770 42fee408f4602159880428c18fabf5ce 375 PRINTS PR01713 Nucleotide sugar epimerase signature 249 264 5.5E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MSG_RS11250 7006237d286ee601217bbac0751cf732 147 Pfam PF10825 Protein of unknown function (DUF2752) 55 102 1.9E-17 T 29-03-2018 IPR021215 Protein of unknown function DUF2752 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 Gene3D G3DSA:3.30.572.10 4 266 4.0E-125 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 PRINTS PR00108 Thymidylate synthase family signature 118 137 2.2E-48 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 PRINTS PR00108 Thymidylate synthase family signature 144 159 2.2E-48 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 PRINTS PR00108 Thymidylate synthase family signature 200 217 2.2E-48 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 PRINTS PR00108 Thymidylate synthase family signature 45 66 2.2E-48 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 PRINTS PR00108 Thymidylate synthase family signature 162 188 2.2E-48 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 SUPERFAMILY SSF55831 5 266 5.1E-122 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 Pfam PF00303 Thymidylate synthase 6 266 1.4E-120 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 Hamap MF_00008 Thymidylate synthase [thyA]. 4 266 38.176 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 88 6.2E-38 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS08765 92ea78721324aa9434aca82580bfee08 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 266 2.1E-90 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 SUPERFAMILY SSF51445 3 359 2.66E-74 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 Pfam PF00128 Alpha amylase, catalytic domain 51 123 7.8E-18 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 Pfam PF00128 Alpha amylase, catalytic domain 138 313 6.1E-23 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 SMART SM00642 13 352 7.9E-37 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 SUPERFAMILY SSF51011 370 435 5.04E-5 T 29-03-2018 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 Gene3D G3DSA:3.20.20.80 1 358 1.5E-72 T 29-03-2018 MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 Pfam PF11941 Domain of unknown function (DUF3459) 344 429 9.6E-6 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) MSG_RS13110 9c9f324509350f4438c4d0a7524883ff 437 Gene3D G3DSA:2.60.40.1180 371 436 1.1E-4 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Gene3D G3DSA:3.50.50.60 239 335 3.2E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 SUPERFAMILY SSF46548 9 155 8.63E-39 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 SUPERFAMILY SSF51971 370 478 7.06E-13 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Gene3D G3DSA:1.10.1060.10 7 142 4.0E-42 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Gene3D G3DSA:3.50.50.60 341 475 3.6E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 480 1.4E-228 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 462 1.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 130 7.0E-24 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 Gene3D G3DSA:3.40.50.720 143 238 8.4E-22 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 7.4E-24 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 7.4E-24 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 7.4E-24 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 7.4E-24 T 29-03-2018 MSG_RS24420 96a40b09d4c917109ee25602d1bb179d 491 SUPERFAMILY SSF51971 143 407 3.65E-69 T 29-03-2018 MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 TIGRFAM TIGR00086 smpB: SsrA-binding protein 20 161 1.2E-58 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 Pfam PF01668 SmpB protein 21 161 1.5E-59 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 SUPERFAMILY SSF74982 15 144 2.35E-51 T 29-03-2018 IPR023620 Small protein B MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 Hamap MF_00023 SsrA-binding protein [smpB]. 1 167 68.586 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 21 144 6.0E-61 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 Gene3D G3DSA:2.40.280.10 21 139 3.8E-50 T 29-03-2018 IPR023620 Small protein B MSG_RS06890 ce1ed0a8a0ef80c1ba935695a29221e8 169 ProSitePatterns PS01317 SsrA-binding protein. 39 51 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site MSG_RS16380 12f876a2b2d5264d50f92f5a2d90200b 71 Pfam PF11272 Protein of unknown function (DUF3072) 14 68 9.0E-30 T 29-03-2018 IPR021425 Protein of unknown function DUF3072 MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 SUPERFAMILY SSF55129 4 59 1.57E-19 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 PIRSF PIRSF002211 1 60 4.3E-28 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 58 4.7E-20 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 59 19.17 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 8.6E-19 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MSG_RS04595 945c59f661c3bc13d75274f80fafc21a 66 Gene3D G3DSA:3.30.1390.20 5 59 7.6E-22 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MSG_RS01850 7c60452cf2d4c203595cbc7bd451ab8c 219 Gene3D G3DSA:3.40.50.150 1 219 4.3E-44 T 29-03-2018 MSG_RS01850 7c60452cf2d4c203595cbc7bd451ab8c 219 SUPERFAMILY SSF53335 3 215 3.91E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01850 7c60452cf2d4c203595cbc7bd451ab8c 219 Pfam PF01596 O-methyltransferase 35 193 1.6E-35 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 SUPERFAMILY SSF48264 60 492 1.96E-99 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 Gene3D G3DSA:1.10.630.10 51 493 1.7E-102 T 29-03-2018 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 433 442 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 424 440 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 295 321 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 399 417 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 440 458 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 89 106 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 350 366 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 PRINTS PR00465 E-class P450 group IV signature 383 397 1.2E-23 T 29-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07310 1ab3e5b57cff122fb345ae71d9f1ab64 493 Pfam PF00067 Cytochrome P450 64 467 8.5E-68 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 SMART SM00347 35 143 2.6E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 Gene3D G3DSA:1.10.10.10 2 161 5.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 1.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 1.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 1.6E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 SUPERFAMILY SSF46785 9 154 1.99E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21375 faecff6b609bc0a79701e659d7db5af0 163 Pfam PF01047 MarR family 42 107 3.2E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS13545 3b07c14899d1b1bc2d05227776141a44 278 Gene3D G3DSA:2.60.120.200 46 278 8.5E-45 T 29-03-2018 MSG_RS13545 3b07c14899d1b1bc2d05227776141a44 278 Pfam PF00722 Glycosyl hydrolases family 16 98 220 9.6E-17 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 MSG_RS13545 3b07c14899d1b1bc2d05227776141a44 278 SUPERFAMILY SSF49899 37 278 2.24E-43 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MSG_RS16685 fff68f691d5e5ac39914becb06f4a7d2 491 Pfam PF01425 Amidase 40 460 1.5E-113 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS16685 fff68f691d5e5ac39914becb06f4a7d2 491 Gene3D G3DSA:3.90.1300.10 20 490 4.3E-120 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS16685 fff68f691d5e5ac39914becb06f4a7d2 491 SUPERFAMILY SSF75304 22 470 1.44E-109 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS16685 fff68f691d5e5ac39914becb06f4a7d2 491 ProSitePatterns PS00571 Amidases signature. 165 196 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 Gene3D G3DSA:3.30.1310.10 1 110 2.3E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 5 98 1.3E-22 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 SUPERFAMILY SSF82607 12 104 2.88E-28 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 20.939 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 Pfam PF02575 YbaB/EbfC DNA-binding family 12 100 1.3E-30 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS23445 bd1f5bf8676048d2e2392663be37038c 116 PIRSF PIRSF004555 3 111 1.2E-38 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS19690 f00ee2fa8f14cabda17707c0eea5dbfd 194 SUPERFAMILY SSF51182 56 192 3.85E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS19690 f00ee2fa8f14cabda17707c0eea5dbfd 194 Gene3D G3DSA:2.60.120.10 7 194 3.9E-32 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS19690 f00ee2fa8f14cabda17707c0eea5dbfd 194 Pfam PF05995 Cysteine dioxygenase type I 58 116 7.1E-12 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 MSG_RS04100 23675db2d94b567ad01a765725cca7c6 147 Hamap MF_00422 Protein translocase subunit SecE [secE]. 89 144 12.804 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04100 23675db2d94b567ad01a765725cca7c6 147 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 93 143 5.2E-18 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS04100 23675db2d94b567ad01a765725cca7c6 147 Gene3D G3DSA:1.20.5.1030 91 142 3.3E-19 T 29-03-2018 MSG_RS04100 23675db2d94b567ad01a765725cca7c6 147 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 91 147 2.0E-21 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MSG_RS04100 23675db2d94b567ad01a765725cca7c6 147 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 94 122 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MSG_RS23455 77e545d7a14a2c01c3caaacb977feb81 145 Gene3D G3DSA:3.30.530.20 2 145 3.8E-14 T 29-03-2018 IPR023393 START-like domain MSG_RS23455 77e545d7a14a2c01c3caaacb977feb81 145 SUPERFAMILY SSF55961 4 133 1.15E-13 T 29-03-2018 MSG_RS23455 77e545d7a14a2c01c3caaacb977feb81 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 5.2E-22 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS23455 77e545d7a14a2c01c3caaacb977feb81 145 PIRSF PIRSF017371 1 145 7.9E-84 T 29-03-2018 IPR014488 Uncharacterised conserved protein UCP017371 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 Gene3D G3DSA:3.40.47.10 263 378 6.1E-26 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 SUPERFAMILY SSF53901 4 258 7.27E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 Gene3D G3DSA:3.40.47.10 1 262 9.7E-56 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 ProSitePatterns PS00737 Thiolases signature 2. 327 343 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 Pfam PF02803 Thiolase, C-terminal domain 259 379 1.6E-36 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 379 1.4E-127 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 Pfam PF00108 Thiolase, N-terminal domain 5 250 1.5E-71 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 PIRSF PIRSF000429 1 382 2.3E-118 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS21285 247fc536202ecbbbbe80aad3b4081958 382 SUPERFAMILY SSF53901 259 380 6.2E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS03200 ee1e4e37dfa6a1f8597dee78d61dfc41 163 Pfam PF07883 Cupin domain 58 126 2.3E-16 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MSG_RS03200 ee1e4e37dfa6a1f8597dee78d61dfc41 163 SUPERFAMILY SSF51182 17 138 3.34E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS03200 ee1e4e37dfa6a1f8597dee78d61dfc41 163 Gene3D G3DSA:2.60.120.10 14 152 2.5E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS07515 9ae7dad382c90c079be724c3a37113b5 245 Gene3D G3DSA:2.160.10.10 49 244 9.8E-30 T 29-03-2018 MSG_RS07515 9ae7dad382c90c079be724c3a37113b5 245 SUPERFAMILY SSF51161 34 218 5.76E-32 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS07515 9ae7dad382c90c079be724c3a37113b5 245 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 164 198 1.4E-6 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 Gene3D G3DSA:3.30.930.10 4 326 9.9E-67 T 29-03-2018 MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 421 31.318 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 Pfam PF13393 Histidyl-tRNA synthetase 13 312 2.2E-44 T 29-03-2018 MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 SUPERFAMILY SSF52954 328 420 1.24E-21 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 Pfam PF03129 Anticodon binding domain 332 418 1.4E-12 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 Gene3D G3DSA:3.40.50.800 327 422 6.7E-18 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 SUPERFAMILY SSF55681 9 317 2.3E-85 T 29-03-2018 MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 410 1.1E-133 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MSG_RS09745 e393774294b79387b1b37c3d6508f08b 422 PIRSF PIRSF001549 4 421 3.3E-109 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 SUPERFAMILY SSF82866 123 340 1.03E-29 T 29-03-2018 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 Pfam PF03176 MMPL family 508 738 3.6E-29 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 Pfam PF03176 MMPL family 44 356 4.3E-49 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 SUPERFAMILY SSF82866 516 735 2.09E-26 T 29-03-2018 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 Gene3D G3DSA:1.20.1640.10 510 735 2.4E-29 T 29-03-2018 MSG_RS19210 db64f96db9dd3d18aeb322717ae4bec4 784 Gene3D G3DSA:1.20.1640.10 132 341 7.5E-31 T 29-03-2018 MSG_RS07020 48e95acad1bb35d37644ba8423da0474 146 Pfam PF00072 Response regulator receiver domain 9 130 1.6E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS07020 48e95acad1bb35d37644ba8423da0474 146 Gene3D G3DSA:3.40.50.2300 1 134 1.5E-30 T 29-03-2018 MSG_RS07020 48e95acad1bb35d37644ba8423da0474 146 SUPERFAMILY SSF52172 5 132 8.11E-32 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS07020 48e95acad1bb35d37644ba8423da0474 146 SMART SM00448 7 129 6.5E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 SUPERFAMILY SSF47819 622 700 2.62E-21 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Pfam PF00570 HRDC domain 632 698 9.8E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 SMART SM00341 628 701 1.4E-17 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Pfam PF13361 UvrD-like helicase C-terminal domain 296 418 8.2E-17 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Pfam PF13361 UvrD-like helicase C-terminal domain 494 564 5.4E-19 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Gene3D G3DSA:1.10.150.80 598 700 8.4E-23 T 29-03-2018 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Pfam PF13245 AAA domain 19 274 1.1E-37 T 29-03-2018 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Gene3D G3DSA:3.40.50.300 293 589 4.9E-54 T 29-03-2018 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 Gene3D G3DSA:3.40.50.300 7 292 3.5E-49 T 29-03-2018 MSG_RS06305 8d6d35ceeb9daf90b7deedeb3c414d4c 701 SUPERFAMILY SSF52540 5 585 9.65E-124 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 SUPERFAMILY SSF51905 7 287 1.19E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 SUPERFAMILY SSF51905 418 477 1.19E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 SUPERFAMILY SSF54373 303 406 4.05E-14 T 29-03-2018 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 PIRSF PIRSF000137 2 319 1.2E-50 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 PIRSF PIRSF000137 411 479 4.6E-18 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 PIRSF PIRSF000137 309 410 1.4E-10 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 Pfam PF05199 GMC oxidoreductase 358 474 2.0E-29 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 TIGRFAM TIGR03970 Rv0697: dehydrogenase, Rv0697 family 8 478 1.0E-208 T 29-03-2018 IPR023978 Glucose-methanol-choline oxidoreductase, actinobacteria MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 Pfam PF00732 GMC oxidoreductase 9 299 1.8E-49 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MSG_RS04365 8aad86d4d062e5abdf36d87feaccb64d 479 Gene3D G3DSA:3.50.50.60 1 478 2.4E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 SMART SM00880 237 508 2.1E-59 T 29-03-2018 IPR007899 CHAD domain MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 SUPERFAMILY SSF55154 10 229 8.67E-44 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 Gene3D G3DSA:2.40.320.10 9 234 4.2E-38 T 29-03-2018 MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 Pfam PF01928 CYTH domain 12 197 7.7E-14 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 SMART SM01118 11 220 5.2E-17 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MSG_RS15525 98a9914ee89a50b6c1de9a1d87643ebc 525 Pfam PF05235 CHAD domain 238 475 4.1E-45 T 29-03-2018 IPR007899 CHAD domain MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 SMART SM00244 35 192 2.1E-54 T 29-03-2018 IPR001107 Band 7 domain MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 144 167 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 212 235 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 168 186 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 187 208 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 89 110 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 42 64 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 PRINTS PR00721 Stomatin signature 124 141 3.6E-60 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 SUPERFAMILY SSF117892 66 199 2.22E-38 T 29-03-2018 IPR001107 Band 7 domain MSG_RS14085 00598cd2a73f0d012c92b9fa0d4f9f9c 292 Pfam PF01145 SPFH domain / Band 7 family 39 209 7.3E-35 T 29-03-2018 IPR001107 Band 7 domain MSG_RS17325 356f44da1e63c988e1e53f509af82d0a 162 PIRSF PIRSF002070 2 153 2.9E-27 T 29-03-2018 MSG_RS17325 356f44da1e63c988e1e53f509af82d0a 162 Pfam PF00436 Single-strand binding protein family 7 103 1.5E-16 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MSG_RS17325 356f44da1e63c988e1e53f509af82d0a 162 SUPERFAMILY SSF50249 7 132 3.26E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS17325 356f44da1e63c988e1e53f509af82d0a 162 Gene3D G3DSA:2.40.50.140 1 116 2.9E-28 T 29-03-2018 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 SUPERFAMILY SSF48498 86 198 3.71E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 Gene3D G3DSA:1.10.357.10 56 200 6.9E-17 T 29-03-2018 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 190 7.4E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 Gene3D G3DSA:1.10.10.60 6 55 2.2E-14 T 29-03-2018 MSG_RS06660 866b4a3a3f458eb0122361de7c250e91 200 SUPERFAMILY SSF46689 17 77 2.92E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01540 6de6ea1e4bc3e51f43322add6f8da9a9 153 Pfam PF07080 Protein of unknown function (DUF1348) 9 137 1.6E-64 T 29-03-2018 IPR009783 Protein of unknown function DUF1348 MSG_RS01540 6de6ea1e4bc3e51f43322add6f8da9a9 153 Gene3D G3DSA:3.10.450.50 12 150 6.7E-63 T 29-03-2018 MSG_RS01540 6de6ea1e4bc3e51f43322add6f8da9a9 153 SUPERFAMILY SSF54427 3 144 1.08E-71 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 SUPERFAMILY SSF48498 101 198 2.86E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 Gene3D G3DSA:1.10.260.40 49 63 0.0043 T 29-03-2018 MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 60 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 Gene3D G3DSA:1.10.357.10 89 217 8.3E-9 T 29-03-2018 MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 SUPERFAMILY SSF46689 16 74 8.21E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14380 d76ad788db341f9f84f384acc93d6957 219 Gene3D G3DSA:1.10.10.60 5 48 6.8E-14 T 29-03-2018 MSG_RS03495 2b501d2ba9c627305a36612dd6d5e22b 270 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 20 265 1.0E-125 T 29-03-2018 MSG_RS11385 bbae8fac20b12880bd7f787a68f8a603 529 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 81 215 3.3E-6 T 29-03-2018 MSG_RS13415 e7850907e4754d40327fd7771f482a71 357 Pfam PF00144 Beta-lactamase 48 345 3.3E-46 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS13415 e7850907e4754d40327fd7771f482a71 357 Gene3D G3DSA:3.40.710.10 23 357 6.5E-60 T 29-03-2018 MSG_RS13415 e7850907e4754d40327fd7771f482a71 357 SUPERFAMILY SSF56601 40 348 4.23E-62 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS07920 932cefdd124677e6f60b8ba1a4405096 107 Pfam PF05305 Protein of unknown function (DUF732) 6 98 3.8E-27 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS18140 4ac2890f762ef10598a16965bf1dbd46 151 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 21 133 4.0E-20 T 29-03-2018 MSG_RS18140 4ac2890f762ef10598a16965bf1dbd46 151 SUPERFAMILY SSF54593 17 149 7.43E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS18140 4ac2890f762ef10598a16965bf1dbd46 151 Gene3D G3DSA:3.10.180.10 12 151 1.2E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS18140 4ac2890f762ef10598a16965bf1dbd46 151 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 20 148 2.0E-39 T 29-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 MSG_RS15330 01da663b952a0940ca7403c978341250 139 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 7.1E-50 T 29-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MSG_RS15330 01da663b952a0940ca7403c978341250 139 PIRSF PIRSF017385 1 139 1.1E-49 T 29-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 SUPERFAMILY SSF46689 10 90 8.48E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 Gene3D G3DSA:1.10.10.60 6 42 1.1E-11 T 29-03-2018 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 7.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 3.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 Gene3D G3DSA:1.10.260.40 43 107 2.8E-10 T 29-03-2018 MSG_RS18655 f2751d1b2e5e819ea7c2ee6ce34f28e6 208 Gene3D G3DSA:1.10.357.10 152 207 0.15 T 29-03-2018 MSG_RS22625 adbd468c6393d2cf06224b80ca9d4ff3 188 Gene3D G3DSA:2.30.110.10 3 188 2.0E-50 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS22625 adbd468c6393d2cf06224b80ca9d4ff3 188 Pfam PF01613 Flavin reductase like domain 16 161 1.8E-36 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS22625 adbd468c6393d2cf06224b80ca9d4ff3 188 SMART SM00903 15 160 6.8E-58 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS22625 adbd468c6393d2cf06224b80ca9d4ff3 188 SUPERFAMILY SSF50475 5 163 3.97E-48 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PIRSF PIRSF000097 5 312 3.1E-89 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PRINTS PR00069 Aldo-keto reductase signature 228 252 1.0E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.0E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.0E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PRINTS PR00069 Aldo-keto reductase signature 188 217 1.0E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 PRINTS PR00069 Aldo-keto reductase signature 154 171 1.0E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 Gene3D G3DSA:3.20.20.100 9 302 4.6E-86 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 Pfam PF00248 Aldo/keto reductase family 24 289 1.5E-41 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 47 64 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS23935 dc24c5f4fc82688d5a21b1b6133d6c10 315 SUPERFAMILY SSF51430 14 291 2.23E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS22770 753e907005b90af43cf78d988cbe2f73 251 Gene3D G3DSA:3.40.50.1820 5 251 1.5E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22770 753e907005b90af43cf78d988cbe2f73 251 Pfam PF12697 Alpha/beta hydrolase family 16 243 1.4E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22770 753e907005b90af43cf78d988cbe2f73 251 SUPERFAMILY SSF53474 9 249 1.04E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05535 603b5da0989fd90f6188811509655f10 327 SUPERFAMILY SSF53300 87 289 5.93E-27 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05535 603b5da0989fd90f6188811509655f10 327 Pfam PF13519 von Willebrand factor type A domain 92 202 1.7E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05535 603b5da0989fd90f6188811509655f10 327 SMART SM00327 89 281 4.8E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS05535 603b5da0989fd90f6188811509655f10 327 Gene3D G3DSA:3.40.50.410 84 294 2.2E-34 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS02425 0e5e986bd7ca0e845b449f68d0d8d8c0 454 SUPERFAMILY SSF53649 5 415 8.58E-88 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS02425 0e5e986bd7ca0e845b449f68d0d8d8c0 454 Gene3D G3DSA:3.30.1120.10 316 423 3.4E-17 T 29-03-2018 MSG_RS02425 0e5e986bd7ca0e845b449f68d0d8d8c0 454 Pfam PF00884 Sulfatase 5 281 2.7E-43 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS02425 0e5e986bd7ca0e845b449f68d0d8d8c0 454 ProSitePatterns PS00523 Sulfatases signature 1. 49 61 - T 29-03-2018 IPR024607 Sulfatase, conserved site MSG_RS02425 0e5e986bd7ca0e845b449f68d0d8d8c0 454 Gene3D G3DSA:3.40.720.10 4 315 4.8E-59 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS11315 ac4ba95b373414891c51f496ebdedca7 150 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 61 128 6.9E-13 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS11315 ac4ba95b373414891c51f496ebdedca7 150 SUPERFAMILY SSF50249 24 129 2.23E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS11315 ac4ba95b373414891c51f496ebdedca7 150 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 24 59 5.1E-10 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS11315 ac4ba95b373414891c51f496ebdedca7 150 Gene3D G3DSA:2.40.50.140 64 129 1.4E-8 T 29-03-2018 MSG_RS10565 cc3e7cba3e2a5bf9d1750909b7bd5c17 262 Pfam PF13412 Winged helix-turn-helix DNA-binding 44 85 1.6E-7 T 29-03-2018 MSG_RS10565 cc3e7cba3e2a5bf9d1750909b7bd5c17 262 SUPERFAMILY SSF46785 42 232 3.62E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10565 cc3e7cba3e2a5bf9d1750909b7bd5c17 262 Gene3D G3DSA:1.10.10.10 19 192 1.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11360 c19d8a120ff21f3f9764665a339d3b8c 146 Pfam PF04167 Protein of unknown function (DUF402) 28 95 3.1E-14 T 29-03-2018 IPR007295 Domain of unknown function DUF402 MSG_RS11360 c19d8a120ff21f3f9764665a339d3b8c 146 Gene3D G3DSA:2.40.380.10 1 140 3.1E-43 T 29-03-2018 IPR007295 Domain of unknown function DUF402 MSG_RS11360 c19d8a120ff21f3f9764665a339d3b8c 146 PIRSF PIRSF012622 1 146 2.2E-71 T 29-03-2018 IPR014465 Uncharacterised conserved protein UCP012622 MSG_RS11360 c19d8a120ff21f3f9764665a339d3b8c 146 SUPERFAMILY SSF159234 1 144 5.23E-43 T 29-03-2018 IPR007295 Domain of unknown function DUF402 MSG_RS23205 f74ae3ea6c73c0a3386bcc9474dc1ce9 98 Pfam PF13834 Domain of unknown function (DUF4193) 4 98 2.9E-28 T 29-03-2018 IPR025242 Protein of unknown function DUF4193 MSG_RS14255 91903754920255bf3333c01cfffc73f3 435 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 302 1.3E-77 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14255 91903754920255bf3333c01cfffc73f3 435 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 435 1.6E-100 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS14255 91903754920255bf3333c01cfffc73f3 435 Pfam PF02470 MlaD protein 44 124 3.2E-13 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS11110 fa43b8da498ac43172e16ec46aef0186 75 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 14 74 1.0E-24 T 29-03-2018 MSG_RS04175 22fe9170bfe3f9f9cafbc2f97b7e782f 301 Gene3D G3DSA:3.30.420.40 142 285 2.1E-40 T 29-03-2018 MSG_RS04175 22fe9170bfe3f9f9cafbc2f97b7e782f 301 Gene3D G3DSA:3.30.420.40 1 141 7.7E-38 T 29-03-2018 MSG_RS04175 22fe9170bfe3f9f9cafbc2f97b7e782f 301 Pfam PF00480 ROK family 4 299 2.8E-58 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MSG_RS04175 22fe9170bfe3f9f9cafbc2f97b7e782f 301 SUPERFAMILY SSF53067 1 299 1.63E-56 T 29-03-2018 MSG_RS04175 22fe9170bfe3f9f9cafbc2f97b7e782f 301 ProSitePatterns PS01125 ROK family signature. 134 161 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MSG_RS14430 b2cfaeca5e20ad4feffaf0fa98b01e9e 412 SUPERFAMILY SSF51621 89 325 2.28E-14 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS14430 b2cfaeca5e20ad4feffaf0fa98b01e9e 412 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 117 286 5.4E-5 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MSG_RS14430 b2cfaeca5e20ad4feffaf0fa98b01e9e 412 Gene3D G3DSA:3.20.20.360 45 367 5.5E-29 T 29-03-2018 MSG_RS13185 243e83e6e935a269b1ae902074ed6581 132 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 19 132 1.5E-30 T 29-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 56.341 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 322 3.5E-146 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 151 8.0E-31 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 Gene3D G3DSA:3.40.50.720 7 156 1.5E-22 T 29-03-2018 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 SUPERFAMILY SSF51735 4 155 2.53E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18725 b0513846cb175c6eba656279226ee574 329 SUPERFAMILY SSF56327 157 325 3.86E-61 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 PIRSF PIRSF000102 3 327 5.2E-57 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 29-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 Gene3D G3DSA:3.90.110.10 157 325 1.9E-55 T 29-03-2018 MSG_RS18725 b0513846cb175c6eba656279226ee574 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 324 3.6E-35 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MSG_RS07555 6732abc6c8a210abab820d7f152e9e11 428 Gene3D G3DSA:3.40.50.2000 252 391 7.7E-28 T 29-03-2018 MSG_RS07555 6732abc6c8a210abab820d7f152e9e11 428 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 192 374 6.0E-8 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 MSG_RS07555 6732abc6c8a210abab820d7f152e9e11 428 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 10 406 2.2E-39 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 MSG_RS07555 6732abc6c8a210abab820d7f152e9e11 428 Gene3D G3DSA:3.40.50.2000 3 251 1.4E-30 T 29-03-2018 MSG_RS07555 6732abc6c8a210abab820d7f152e9e11 428 SUPERFAMILY SSF53756 4 405 1.48E-68 T 29-03-2018 MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 Pfam PF13638 PIN domain 7 145 5.8E-29 T 29-03-2018 IPR002716 PIN domain MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 SUPERFAMILY SSF88723 97 140 6.54E-9 T 29-03-2018 IPR029060 PIN domain-like MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 SUPERFAMILY SSF88723 6 64 6.54E-9 T 29-03-2018 IPR029060 PIN domain-like MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 SMART SM00670 5 132 1.3E-21 T 29-03-2018 IPR002716 PIN domain MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 SUPERFAMILY SSF52540 220 383 2.6E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 Gene3D G3DSA:3.40.50.300 220 424 3.8E-17 T 29-03-2018 MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 Gene3D G3DSA:3.40.50.1010 4 176 1.1E-29 T 29-03-2018 IPR029060 PIN domain-like MSG_RS19565 051703035aabb18fd2a3b48b88823d1b 433 Pfam PF02562 PhoH-like protein 222 426 4.7E-52 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 Gene3D G3DSA:3.40.50.2300 47 159 5.7E-11 T 29-03-2018 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 SUPERFAMILY SSF53822 99 309 7.38E-28 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 Pfam PF13377 Periplasmic binding protein-like domain 152 309 2.0E-29 T 29-03-2018 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 Gene3D G3DSA:1.10.260.40 1 46 2.0E-15 T 29-03-2018 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 SUPERFAMILY SSF47413 1 52 4.97E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 41 9.3E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 Gene3D G3DSA:3.40.50.2300 160 289 8.5E-26 T 29-03-2018 MSG_RS16250 ff5fd19a7f3c8495c975f257dc12fbf9 309 SMART SM00354 1 64 9.4E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 PIRSF PIRSF002741 30 537 4.2E-55 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 Gene3D G3DSA:3.10.105.10 325 510 1.1E-34 T 29-03-2018 MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 459 1.3E-44 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 Gene3D G3DSA:3.40.190.10 169 324 1.4E-23 T 29-03-2018 MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 SUPERFAMILY SSF53850 31 535 7.24E-86 T 29-03-2018 MSG_RS23075 36d946a31c1ee40cd1fe3e912b08ad62 538 Gene3D G3DSA:3.90.76.10 56 168 1.3E-18 T 29-03-2018 MSG_RS21780 c56105b77536dae0f2b6aba16d25e2cd 441 SUPERFAMILY SSF56784 199 366 1.4E-14 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21780 c56105b77536dae0f2b6aba16d25e2cd 441 SUPERFAMILY SSF56784 92 109 1.4E-14 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21780 c56105b77536dae0f2b6aba16d25e2cd 441 Pfam PF12710 haloacid dehalogenase-like hydrolase 220 360 3.4E-11 T 29-03-2018 MSG_RS21780 c56105b77536dae0f2b6aba16d25e2cd 441 Gene3D G3DSA:3.40.50.1000 216 387 5.3E-8 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21780 c56105b77536dae0f2b6aba16d25e2cd 441 Gene3D G3DSA:3.40.190.10 22 124 0.25 T 29-03-2018 MSG_RS21335 ba976994ac8d70cbd51c99cb366f8764 253 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 97 229 7.2E-20 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21335 ba976994ac8d70cbd51c99cb366f8764 253 SUPERFAMILY SSF47203 102 241 6.93E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21335 ba976994ac8d70cbd51c99cb366f8764 253 Gene3D G3DSA:1.20.140.10 98 225 9.8E-28 T 29-03-2018 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 Gene3D G3DSA:1.20.1640.10 164 387 2.9E-28 T 29-03-2018 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 TIGRFAM TIGR00833 actII: transport protein 43 950 1.9E-288 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 Gene3D G3DSA:1.20.1640.10 739 947 6.8E-26 T 29-03-2018 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 SUPERFAMILY SSF82866 176 371 6.15E-26 T 29-03-2018 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 SUPERFAMILY SSF82866 722 950 4.58E-28 T 29-03-2018 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 Pfam PF03176 MMPL family 76 403 6.4E-107 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS16995 8586583192bfd0013341f9e61f1a69fc 979 Pfam PF03176 MMPL family 630 952 1.1E-92 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 Gene3D G3DSA:1.10.630.10 1 411 3.3E-63 T 29-03-2018 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 Pfam PF00067 Cytochrome P450 85 378 1.3E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 196 218 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 137 153 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 349 358 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 154 169 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 327 342 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 358 369 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 299 326 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 91 102 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 PRINTS PR00359 B-class P450 signature 282 293 3.5E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17690 c6323e3ca7cc1f0bb1deae77fb97d9d9 411 SUPERFAMILY SSF48264 23 411 3.54E-77 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 Gene3D G3DSA:3.90.1150.10 301 452 2.5E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 17 436 2.1E-204 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 18 436 9.0E-136 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 SUPERFAMILY SSF53383 15 433 3.75E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 Gene3D G3DSA:3.40.640.10 15 299 1.8E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 PIRSF PIRSF001434 4 440 2.8E-125 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS05370 16f26aa9f796919d56b9b8caa74027ea 452 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 211 225 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS12985 b62e877cf7eae779735e116fb1e1e88a 225 Gene3D G3DSA:3.40.50.720 4 130 1.3E-15 T 29-03-2018 MSG_RS12985 b62e877cf7eae779735e116fb1e1e88a 225 SUPERFAMILY SSF51735 5 222 6.3E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12985 b62e877cf7eae779735e116fb1e1e88a 225 Gene3D G3DSA:3.40.50.720 131 221 5.0E-8 T 29-03-2018 MSG_RS12985 b62e877cf7eae779735e116fb1e1e88a 225 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 219 1.7E-17 T 29-03-2018 MSG_RS02640 4b1c0bbb4341261b5cc350c0e75ae396 120 SUPERFAMILY SSF54427 1 110 3.38E-12 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS02640 4b1c0bbb4341261b5cc350c0e75ae396 120 Gene3D G3DSA:3.10.450.50 1 109 2.5E-8 T 29-03-2018 MSG_RS02640 4b1c0bbb4341261b5cc350c0e75ae396 120 Pfam PF12680 SnoaL-like domain 9 103 7.6E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS01870 7930550257ecf3c133129f0a08fd07f4 344 Pfam PF03734 L,D-transpeptidase catalytic domain 202 324 5.7E-18 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS01870 7930550257ecf3c133129f0a08fd07f4 344 Gene3D G3DSA:2.40.440.10 192 326 3.9E-24 T 29-03-2018 MSG_RS01870 7930550257ecf3c133129f0a08fd07f4 344 SUPERFAMILY SSF141523 196 324 5.23E-27 T 29-03-2018 MSG_RS11990 40494a193a9fa0dbc0a2ec12bd076ad7 338 Gene3D G3DSA:3.20.20.30 3 336 1.3E-38 T 29-03-2018 MSG_RS11990 40494a193a9fa0dbc0a2ec12bd076ad7 338 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 19 318 2.7E-94 T 29-03-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted MSG_RS11990 40494a193a9fa0dbc0a2ec12bd076ad7 338 SUPERFAMILY SSF51679 9 327 2.75E-42 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS11990 40494a193a9fa0dbc0a2ec12bd076ad7 338 Pfam PF00296 Luciferase-like monooxygenase 9 307 3.5E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SUPERFAMILY SSF52283 406 485 1.02E-111 T 29-03-2018 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SUPERFAMILY SSF52283 195 242 1.02E-111 T 29-03-2018 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SUPERFAMILY SSF52283 11 157 1.02E-111 T 29-03-2018 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 1.7E-78 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 PIRSF PIRSF001109 1 485 5.4E-195 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 477 1.1E-202 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SUPERFAMILY SSF51735 243 405 9.87E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 Gene3D G3DSA:3.40.50.1480 258 458 9.0E-78 T 29-03-2018 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 484 4.0E-146 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 477 47.743 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SMART SM00996 12 484 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 SMART SM00997 243 405 1.3E-101 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MSG_RS05895 55b98efca4d81ac515611fced7846e11 485 Gene3D G3DSA:3.40.50.1480 3 257 3.3E-108 T 29-03-2018 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Pfam PF13377 Periplasmic binding protein-like domain 177 334 2.7E-25 T 29-03-2018 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Gene3D G3DSA:3.40.50.2300 72 183 1.7E-8 T 29-03-2018 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 SUPERFAMILY SSF53822 79 323 1.3E-22 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 SMART SM00354 17 89 1.4E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 1.0E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Gene3D G3DSA:3.40.50.2300 184 322 7.5E-18 T 29-03-2018 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Gene3D G3DSA:1.10.10.10 9 33 0.17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 Gene3D G3DSA:1.10.260.40 34 71 1.9E-20 T 29-03-2018 MSG_RS00830 023f502a241426f5fdc2a341619c359e 334 SUPERFAMILY SSF47413 17 77 3.78E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS03140 a3a8d4289c98d312aeda64a2668b7bc3 243 SUPERFAMILY SSF49329 77 241 4.58E-43 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS03140 a3a8d4289c98d312aeda64a2668b7bc3 243 Gene3D G3DSA:2.60.40.200 70 241 7.7E-28 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS03140 a3a8d4289c98d312aeda64a2668b7bc3 243 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 84 240 3.1E-28 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS03140 a3a8d4289c98d312aeda64a2668b7bc3 243 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 229 240 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS07650 602f90ddbac29878cb17fcec21197987 393 PIRSF PIRSF005572 1 385 6.3E-112 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MSG_RS07650 602f90ddbac29878cb17fcec21197987 393 Gene3D G3DSA:3.40.640.10 1 229 1.4E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS07650 602f90ddbac29878cb17fcec21197987 393 Pfam PF00266 Aminotransferase class-V 2 369 8.8E-62 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS07650 602f90ddbac29878cb17fcec21197987 393 SUPERFAMILY SSF53383 1 378 1.84E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS07650 602f90ddbac29878cb17fcec21197987 393 Gene3D G3DSA:3.90.1150.10 230 389 1.7E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.6E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 196 6.3E-4 T 29-03-2018 MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 Gene3D G3DSA:3.40.50.720 2 259 4.2E-67 T 29-03-2018 MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 SUPERFAMILY SSF51735 6 255 3.7E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22215 f7cafbac725d743fe9012a962ad4eacf 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 1.8E-54 T 29-03-2018 MSG_RS09850 b3074d61a80fbb6c55482f4297a594e4 888 SUPERFAMILY SSF56059 87 236 2.4E-6 T 29-03-2018 MSG_RS09850 b3074d61a80fbb6c55482f4297a594e4 888 Pfam PF04174 A circularly permuted ATPgrasp 123 451 2.7E-124 T 29-03-2018 IPR007302 Circularly permuted ATPgrasp domain MSG_RS09850 b3074d61a80fbb6c55482f4297a594e4 888 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 547 866 3.9E-66 T 29-03-2018 IPR007296 Domain of unknown function DUF403 MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 Gene3D G3DSA:3.40.50.720 187 244 0.055 T 29-03-2018 MSG_RS18710 d537efa055850e6571980af28c9c7334 274 Pfam PF00106 short chain dehydrogenase 7 201 2.2E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 Gene3D G3DSA:3.40.50.720 1 186 7.7E-52 T 29-03-2018 MSG_RS18710 d537efa055850e6571980af28c9c7334 274 SUPERFAMILY SSF51735 1 258 3.01E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 9.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18710 d537efa055850e6571980af28c9c7334 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS18710 d537efa055850e6571980af28c9c7334 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0083 T 29-03-2018 MSG_RS04990 0b2d05335958bcabd3aef969f4cb6772 371 Gene3D G3DSA:3.40.50.1820 54 351 3.2E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04990 0b2d05335958bcabd3aef969f4cb6772 371 SUPERFAMILY SSF53474 66 345 1.73E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04990 0b2d05335958bcabd3aef969f4cb6772 371 Pfam PF12146 Serine aminopeptidase, S33 85 336 2.3E-23 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MSG_RS23535 9111bca6460cd116ecdcbc0aeb6bfd29 574 Gene3D G3DSA:1.25.40.10 4 155 0.067 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS23535 9111bca6460cd116ecdcbc0aeb6bfd29 574 Gene3D G3DSA:1.25.40.10 191 426 1.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS23535 9111bca6460cd116ecdcbc0aeb6bfd29 574 SUPERFAMILY SSF48452 270 365 2.37E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 Gene3D G3DSA:3.40.47.10 268 389 6.4E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 SUPERFAMILY SSF53901 272 390 2.88E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 8.6E-110 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 PIRSF PIRSF000429 1 391 2.1E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 Pfam PF02803 Thiolase, C-terminal domain 270 390 3.8E-37 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 SUPERFAMILY SSF53901 5 269 3.25E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 Gene3D G3DSA:3.40.47.10 2 267 9.4E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MSG_RS16095 d19130c8ef2645a4e18c69caf9cd6b17 391 Pfam PF00108 Thiolase, N-terminal domain 5 261 5.3E-52 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS01530 13d423adca00589019d800d5fde809a7 275 Gene3D G3DSA:3.90.190.10 19 211 1.7E-21 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MSG_RS01530 13d423adca00589019d800d5fde809a7 275 Pfam PF13350 Tyrosine phosphatase family 7 274 2.8E-57 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type MSG_RS01530 13d423adca00589019d800d5fde809a7 275 SUPERFAMILY SSF52799 7 274 1.7E-55 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 Gene3D G3DSA:3.90.1150.10 9 172 1.5E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 9 433 48.632 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 Gene3D G3DSA:3.90.1150.10 271 432 7.0E-41 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 SUPERFAMILY SSF53383 12 429 5.97E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 21 430 1.2E-163 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 Pfam PF00202 Aminotransferase class-III 35 428 5.5E-117 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11065 7fb7170bceec442a07e6b606c8b41847 438 Gene3D G3DSA:3.90.1150.10 183 270 0.0073 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS07000 2cc12a12ff1ff5ac83640dad14fd563a 183 Pfam PF04471 Restriction endonuclease 64 173 6.3E-26 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 MSG_RS07000 2cc12a12ff1ff5ac83640dad14fd563a 183 SUPERFAMILY SSF52980 69 173 7.24E-24 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MSG_RS07000 2cc12a12ff1ff5ac83640dad14fd563a 183 Gene3D G3DSA:3.40.1350.10 58 173 1.3E-22 T 29-03-2018 MSG_RS08155 a7301207fc9da916fec98e298f095fbe 361 Gene3D G3DSA:2.30.40.10 10 78 1.1E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS08155 a7301207fc9da916fec98e298f095fbe 361 Pfam PF01979 Amidohydrolase family 44 334 7.1E-15 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS08155 a7301207fc9da916fec98e298f095fbe 361 SUPERFAMILY SSF51556 47 323 1.22E-58 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS08155 a7301207fc9da916fec98e298f095fbe 361 Gene3D G3DSA:3.20.20.140 79 324 1.3E-31 T 29-03-2018 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 SUPERFAMILY SSF142984 241 319 4.84E-12 T 29-03-2018 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 SUPERFAMILY SSF142019 28 238 7.59E-47 T 29-03-2018 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 SMART SM00928 323 368 6.5E-8 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 325 408 1.0E-16 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 SUPERFAMILY SSF140490 319 414 1.96E-20 T 29-03-2018 MSG_RS21220 e7057f6b43c48b8295c0fc4414df4bce 435 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 217 3.9E-35 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS13780 52214e566a6e17e0646c0e31fb71ddd9 213 PIRSF PIRSF006324 2 213 1.0E-52 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MSG_RS13780 52214e566a6e17e0646c0e31fb71ddd9 213 Pfam PF01810 LysE type translocator 16 210 4.5E-32 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 PIRSF PIRSF003314 5 345 6.1E-109 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 8 343 34.295 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 SUPERFAMILY SSF51395 31 342 1.71E-65 T 29-03-2018 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 Gene3D G3DSA:3.20.20.70 8 345 4.7E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 Pfam PF01070 FMN-dependent dehydrogenase 174 339 7.2E-19 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 Pfam PF01070 FMN-dependent dehydrogenase 7 102 2.1E-7 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 SMART SM01240 109 345 0.0011 T 29-03-2018 MSG_RS07550 c45477fe28f7e9ee547b6e62e5859d8b 347 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 11 341 5.0E-100 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 SUPERFAMILY SSF69593 25 174 1.7E-14 T 29-03-2018 MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 SUPERFAMILY SSF69593 207 261 1.7E-14 T 29-03-2018 MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 Gene3D G3DSA:3.40.1130.10 16 266 5.5E-13 T 29-03-2018 MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 PIRSF PIRSF016753 4 271 4.6E-88 T 29-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 Pfam PF01553 Acyltransferase 40 167 8.4E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS10435 a07a345dc4857ce19c2bd954cff69c12 271 SMART SM00563 52 171 1.8E-14 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS02355 a02466c17e743be413638e74216ecf13 496 SUPERFAMILY SSF140459 5 177 1.6E-59 T 29-03-2018 MSG_RS02355 a02466c17e743be413638e74216ecf13 496 Pfam PF00823 PPE family 8 164 1.7E-58 T 29-03-2018 IPR000030 PPE family MSG_RS02355 a02466c17e743be413638e74216ecf13 496 Gene3D G3DSA:1.10.287.1060 23 109 1.8E-5 T 29-03-2018 MSG_RS16120 0eeb0d4c405b705bea06011a9cc2477c 563 Pfam PF01566 Natural resistance-associated macrophage protein 86 439 1.5E-79 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.7E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 Gene3D G3DSA:3.40.50.720 13 57 2.2E-5 T 29-03-2018 MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 Gene3D G3DSA:3.40.50.720 58 261 1.6E-51 T 29-03-2018 MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 249 2.5E-51 T 29-03-2018 MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 SUPERFAMILY SSF51735 20 249 2.06E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22530 dd7b5da41ae8d03e39ca06be59671d8a 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS03135 db37ddecffea3706d0ddbf80d3ba3026 160 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 74 159 7.1E-13 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 SUPERFAMILY SSF48256 6 359 5.76E-94 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 Pfam PF00285 Citrate synthase, C-terminal domain 11 348 2.0E-81 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 PRINTS PR00143 Citrate synthase signature 165 180 9.0E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 PRINTS PR00143 Citrate synthase signature 299 315 9.0E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 PRINTS PR00143 Citrate synthase signature 187 215 9.0E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 PRINTS PR00143 Citrate synthase signature 240 260 9.0E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 PRINTS PR00143 Citrate synthase signature 319 333 9.0E-25 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 Gene3D G3DSA:1.10.580.10 84 227 1.7E-35 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 Gene3D G3DSA:1.10.580.10 2 76 4.0E-12 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 ProSitePatterns PS00480 Citrate synthase signature. 247 259 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MSG_RS20705 c3f67aef9fdf383f705411480e4acdf3 373 Gene3D G3DSA:1.10.230.10 228 313 3.2E-21 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain MSG_RS10615 e604db2bfca940e51e9bc6f1ce677697 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 267 2.6E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS10615 e604db2bfca940e51e9bc6f1ce677697 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS10615 e604db2bfca940e51e9bc6f1ce677697 269 SUPERFAMILY SSF52096 3 267 1.01E-71 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS10615 e604db2bfca940e51e9bc6f1ce677697 269 Gene3D G3DSA:1.10.12.10 224 269 6.1E-8 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS10615 e604db2bfca940e51e9bc6f1ce677697 269 Gene3D G3DSA:3.90.226.10 4 223 2.1E-57 T 29-03-2018 MSG_RS16335 14350e53919f236b9a5aa6749bf76d45 224 SUPERFAMILY SSF56784 7 200 5.6E-43 T 29-03-2018 IPR023214 HAD-like domain MSG_RS16335 14350e53919f236b9a5aa6749bf76d45 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 178 3.9E-18 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS16335 14350e53919f236b9a5aa6749bf76d45 224 Gene3D G3DSA:1.10.150.240 23 73 1.4E-14 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MSG_RS16335 14350e53919f236b9a5aa6749bf76d45 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 180 1.0E-21 T 29-03-2018 IPR023214 HAD-like domain MSG_RS16335 14350e53919f236b9a5aa6749bf76d45 224 Gene3D G3DSA:3.40.50.1000 74 208 2.4E-23 T 29-03-2018 IPR023214 HAD-like domain MSG_RS14090 5ab9143b505412949b3f9f34be1c4f8a 473 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 463 3.8E-108 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS14090 5ab9143b505412949b3f9f34be1c4f8a 473 SUPERFAMILY SSF52777 70 154 1.78E-5 T 29-03-2018 MSG_RS14090 5ab9143b505412949b3f9f34be1c4f8a 473 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 271 4.2E-48 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS14090 5ab9143b505412949b3f9f34be1c4f8a 473 Gene3D G3DSA:3.30.559.10 3 186 6.3E-5 T 29-03-2018 MSG_RS14090 5ab9143b505412949b3f9f34be1c4f8a 473 Pfam PF06974 Protein of unknown function (DUF1298) 315 460 1.7E-32 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 Gene3D G3DSA:3.90.1150.10 289 397 2.6E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 SUPERFAMILY SSF53383 13 392 5.92E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 PIRSF PIRSF000521 125 157 1.1 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 PIRSF PIRSF000521 173 394 1.4E-31 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 PIRSF PIRSF000521 4 134 6.0E-11 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 391 1.1E-144 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 Gene3D G3DSA:3.40.640.10 169 288 5.1E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 14 392 42.1 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 Pfam PF00202 Aminotransferase class-III 23 388 9.7E-105 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS11510 d131ac82d2e360bd87e3e99ed115eb3c 398 Gene3D G3DSA:3.90.1150.10 2 159 5.2E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS21105 d3274b0933515cccc274cff7042f77e0 476 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 159 287 1.7E-6 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS21105 d3274b0933515cccc274cff7042f77e0 476 Gene3D G3DSA:3.90.20.10 162 316 1.5E-4 T 29-03-2018 MSG_RS21105 d3274b0933515cccc274cff7042f77e0 476 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 305 9.4E-72 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21105 d3274b0933515cccc274cff7042f77e0 476 Pfam PF02470 MlaD protein 39 113 8.3E-16 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS04635 0b1eecc2c5cb05ff10daefbbfe5f0db9 164 Pfam PF13649 Methyltransferase domain 53 126 1.4E-14 T 29-03-2018 MSG_RS04635 0b1eecc2c5cb05ff10daefbbfe5f0db9 164 Gene3D G3DSA:3.40.50.150 16 155 8.7E-24 T 29-03-2018 MSG_RS04635 0b1eecc2c5cb05ff10daefbbfe5f0db9 164 SUPERFAMILY SSF53335 20 134 8.96E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23795 8389c0e58e9cde66cf827c644047ddae 168 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 24 166 44.469 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MSG_RS23795 8389c0e58e9cde66cf827c644047ddae 168 SUPERFAMILY SSF53927 16 166 2.13E-44 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MSG_RS23795 8389c0e58e9cde66cf827c644047ddae 168 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 69 107 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MSG_RS23795 8389c0e58e9cde66cf827c644047ddae 168 Gene3D G3DSA:3.40.140.10 10 167 1.1E-42 T 29-03-2018 MSG_RS23795 8389c0e58e9cde66cf827c644047ddae 168 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 19 118 5.2E-23 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MSG_RS15250 0263985a09063f752e1483cf950561d5 145 Gene3D G3DSA:3.30.530.20 3 145 2.1E-26 T 29-03-2018 IPR023393 START-like domain MSG_RS15250 0263985a09063f752e1483cf950561d5 145 SUPERFAMILY SSF55961 4 144 2.52E-31 T 29-03-2018 MSG_RS15250 0263985a09063f752e1483cf950561d5 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 143 8.7E-18 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS18170 6397a4f181d65d58e09324113e280d6c 441 SUPERFAMILY SSF52777 22 144 1.06E-6 T 29-03-2018 MSG_RS18170 6397a4f181d65d58e09324113e280d6c 441 Gene3D G3DSA:3.30.559.10 4 172 6.2E-7 T 29-03-2018 MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 Gene3D G3DSA:3.40.50.1240 161 365 8.9E-50 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 Pfam PF13456 Reverse transcriptase-like 7 129 1.1E-26 T 29-03-2018 MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 168 360 2.9E-59 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 PIRSF PIRSF036922 1 365 2.5E-185 T 29-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 SMART SM00855 167 321 2.9E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 SUPERFAMILY SSF53098 3 128 2.15E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 SUPERFAMILY SSF53254 165 365 4.84E-54 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS15550 4aa62ed9ada0689675ba9444bee141e9 365 Gene3D G3DSA:3.30.420.10 2 157 1.8E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 SUPERFAMILY SSF52029 182 374 2.99E-75 T 29-03-2018 IPR027409 GroEL-like apical domain MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 PRINTS PR00298 60kDa chaperonin signature 26 52 3.1E-67 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 PRINTS PR00298 60kDa chaperonin signature 266 289 3.1E-67 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 PRINTS PR00298 60kDa chaperonin signature 82 109 3.1E-67 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 PRINTS PR00298 60kDa chaperonin signature 396 417 3.1E-67 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 PRINTS PR00298 60kDa chaperonin signature 348 373 3.1E-67 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 SUPERFAMILY SSF54849 136 202 2.15E-21 T 29-03-2018 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 39.039 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 SUPERFAMILY SSF48592 6 133 2.17E-70 T 29-03-2018 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 SUPERFAMILY SSF48592 404 520 2.17E-70 T 29-03-2018 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 Gene3D G3DSA:1.10.560.10 2 189 8.7E-37 T 29-03-2018 IPR027413 GroEL-like equatorial domain MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 Gene3D G3DSA:3.50.7.10 190 371 2.3E-86 T 29-03-2018 IPR027409 GroEL-like apical domain MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 3.3E-86 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 1.2E-220 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MSG_RS05035 ad125aa92d176d41e8a18fdb4878e135 540 Gene3D G3DSA:1.10.560.10 372 515 1.9E-25 T 29-03-2018 IPR027413 GroEL-like equatorial domain MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 379 6.2E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Gene3D G3DSA:1.20.140.10 216 394 4.7E-50 T 29-03-2018 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 PIRSF PIRSF016578 4 190 7.2E-5 T 29-03-2018 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 PIRSF PIRSF016578 232 367 7.5E-13 T 29-03-2018 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Gene3D G3DSA:1.10.540.10 1 120 3.5E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 196 1.9E-16 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 SUPERFAMILY SSF56645 1 223 3.66E-44 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 116 3.2E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 SUPERFAMILY SSF47203 224 384 1.03E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS10050 f43e587e80df154f34423a824dca76cf 399 Gene3D G3DSA:2.40.110.10 121 215 1.1E-25 T 29-03-2018 MSG_RS22540 6c2881c8f38170c1d370467d69f8cf2d 294 Pfam PF01144 Coenzyme A transferase 7 233 7.2E-47 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MSG_RS22540 6c2881c8f38170c1d370467d69f8cf2d 294 Gene3D G3DSA:3.40.1080.10 1 255 1.1E-54 T 29-03-2018 MSG_RS22540 6c2881c8f38170c1d370467d69f8cf2d 294 SUPERFAMILY SSF100950 3 279 2.61E-64 T 29-03-2018 MSG_RS22540 6c2881c8f38170c1d370467d69f8cf2d 294 SMART SM00882 5 233 9.2E-26 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MSG_RS20945 dfd20cbc1af02fac17d56c1a2966a12d 142 Gene3D G3DSA:1.10.10.10 1 136 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20945 dfd20cbc1af02fac17d56c1a2966a12d 142 Pfam PF12802 MarR family 31 84 2.5E-9 T 29-03-2018 MSG_RS20945 dfd20cbc1af02fac17d56c1a2966a12d 142 SUPERFAMILY SSF46785 9 120 9.09E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20945 dfd20cbc1af02fac17d56c1a2966a12d 142 SMART SM00347 26 121 0.0014 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 Gene3D G3DSA:1.10.357.10 50 188 3.4E-11 T 29-03-2018 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 SUPERFAMILY SSF46689 2 56 3.07E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 SUPERFAMILY SSF48498 64 179 4.0E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 Gene3D G3DSA:1.10.10.60 1 49 7.8E-15 T 29-03-2018 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 5.1E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15120 9e4599cc52eda7c65e488a3835355949 188 Pfam PF16859 Bacterial transcriptional repressor C-terminal 64 174 5.6E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 Pfam PF02470 MlaD protein 39 114 3.7E-17 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 PRINTS PR01217 Proline rich extensin signature 398 419 9.0E-9 T 29-03-2018 MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 PRINTS PR01217 Proline rich extensin signature 427 443 9.0E-9 T 29-03-2018 MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 PRINTS PR01217 Proline rich extensin signature 332 348 9.0E-9 T 29-03-2018 MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 PRINTS PR01217 Proline rich extensin signature 453 470 9.0E-9 T 29-03-2018 MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 PRINTS PR01217 Proline rich extensin signature 479 504 9.0E-9 T 29-03-2018 MSG_RS22255 842f53f5c852aa350014c01036988a1c 576 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 6.2E-81 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 SUPERFAMILY SSF52540 270 417 1.36E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 SUPERFAMILY SSF52540 70 238 1.36E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 Gene3D G3DSA:3.40.50.300 37 253 6.7E-28 T 29-03-2018 MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 Pfam PF00270 DEAD/DEAH box helicase 62 236 1.9E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 23 771 0.0 T 29-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 Gene3D G3DSA:3.40.50.300 285 475 6.1E-21 T 29-03-2018 MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 SMART SM00490 328 406 2.8E-15 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 Pfam PF09369 Domain of unknown function (DUF1998) 664 744 8.6E-18 T 29-03-2018 IPR018973 DEAD/DEAH-box helicase, putative MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 SMART SM00487 55 266 1.3E-22 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS23000 a21923b34353934baf41e4029a2ee083 773 Pfam PF00271 Helicase conserved C-terminal domain 299 406 6.8E-11 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PIRSF PIRSF036406 5 338 2.4E-111 T 29-03-2018 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 SUPERFAMILY SSF54211 3 176 2.73E-37 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 Gene3D G3DSA:3.30.230.10 2 191 6.0E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 Pfam PF00288 GHMP kinases N terminal domain 99 167 2.9E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 Gene3D G3DSA:3.30.70.890 192 334 2.9E-23 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PRINTS PR00960 LmbP protein signature 10 25 6.4E-39 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PRINTS PR00960 LmbP protein signature 105 126 6.4E-39 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PRINTS PR00960 LmbP protein signature 282 301 6.4E-39 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PRINTS PR00960 LmbP protein signature 254 278 6.4E-39 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 PRINTS PR00960 LmbP protein signature 147 166 6.4E-39 T 29-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 Pfam PF08544 GHMP kinases C terminal 239 316 3.6E-9 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS20135 f2c0ded3d5f683512038433430dbd8c7 338 SUPERFAMILY SSF55060 191 336 6.37E-30 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS01455 03b029446763ac221c54fc9f4b878019 175 Pfam PF01625 Peptide methionine sulfoxide reductase 6 153 4.5E-58 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MSG_RS01455 03b029446763ac221c54fc9f4b878019 175 SUPERFAMILY SSF55068 2 162 1.31E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MSG_RS01455 03b029446763ac221c54fc9f4b878019 175 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 153 4.2E-51 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MSG_RS01455 03b029446763ac221c54fc9f4b878019 175 Gene3D G3DSA:3.30.1060.10 3 168 1.1E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MSG_RS01455 03b029446763ac221c54fc9f4b878019 175 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 4 159 34.37 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MSG_RS09200 9902a37448eb5459ff2b71369c907e80 362 SUPERFAMILY SSF52540 88 204 7.27E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09200 9902a37448eb5459ff2b71369c907e80 362 Gene3D G3DSA:3.40.50.300 44 223 1.0E-5 T 29-03-2018 MSG_RS09200 9902a37448eb5459ff2b71369c907e80 362 Pfam PF03969 AFG1-like ATPase 27 239 1.8E-63 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 MSG_RS18460 8c6fea5201eb41691e863a62a1fdaad6 489 Pfam PF00361 Proton-conducting membrane transporter 124 418 9.9E-45 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18460 8c6fea5201eb41691e863a62a1fdaad6 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 3.5E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18460 8c6fea5201eb41691e863a62a1fdaad6 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 3.5E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18460 8c6fea5201eb41691e863a62a1fdaad6 489 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 3.5E-6 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18460 8c6fea5201eb41691e863a62a1fdaad6 489 Gene3D G3DSA:1.10.287.70 1 403 0.19 T 29-03-2018 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 SUPERFAMILY SSF51161 301 399 2.11E-17 T 29-03-2018 IPR011004 Trimeric LpxA-like MSG_RS18840 5a548959d5b8ca710550e526835da481 404 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 5.2E-144 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 Gene3D G3DSA:3.90.550.10 1 281 1.0E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS18840 5a548959d5b8ca710550e526835da481 404 SUPERFAMILY SSF53448 342 358 4.46E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS18840 5a548959d5b8ca710550e526835da481 404 SUPERFAMILY SSF53448 7 280 4.46E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS18840 5a548959d5b8ca710550e526835da481 404 Gene3D G3DSA:2.160.10.10 282 404 2.6E-11 T 29-03-2018 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 Pfam PF00483 Nucleotidyl transferase 9 276 2.3E-70 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MSG_RS18840 5a548959d5b8ca710550e526835da481 404 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.242 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 Gene3D G3DSA:3.40.50.300 25 183 9.1E-26 T 29-03-2018 MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 Pfam PF13177 DNA polymerase III, delta subunit 32 182 4.6E-35 T 29-03-2018 MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 SUPERFAMILY SSF52540 6 223 1.29E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 SMART SM00382 39 185 0.0027 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 33 219 3.7E-57 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS22975 19b7949c7bbf248612b4ca22394fb8b9 405 Gene3D G3DSA:1.20.272.10 299 405 5.2E-24 T 29-03-2018 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 Pfam PF00107 Zinc-binding dehydrogenase 197 328 1.7E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 370 3.7E-177 T 29-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 SMART SM00829 15 368 4.0E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 SUPERFAMILY SSF50129 322 370 1.04E-10 T 29-03-2018 IPR011032 GroES-like MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 Gene3D G3DSA:3.90.180.10 3 180 5.7E-47 T 29-03-2018 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 Gene3D G3DSA:3.40.50.10730 181 311 2.3E-19 T 29-03-2018 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 SUPERFAMILY SSF50129 1 182 6.85E-60 T 29-03-2018 IPR011032 GroES-like MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 SUPERFAMILY SSF51735 158 337 1.98E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22040 5aeb8200440007ba7a79e7b546bad045 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 155 1.1E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Gene3D G3DSA:1.10.10.60 80 113 2.5E-4 T 29-03-2018 MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 SUPERFAMILY SSF46689 9 108 7.88E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Gene3D G3DSA:1.10.10.10 41 79 0.22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Gene3D G3DSA:3.30.420.10 132 316 7.1E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Gene3D G3DSA:1.10.10.10 4 40 4.0E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Pfam PF00665 Integrase core domain 138 275 3.5E-26 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 Pfam PF13011 leucine-zipper of insertion element IS481 2 81 5.8E-21 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS23470 f84af264d3937360ad21af1af731c6be 316 SUPERFAMILY SSF53098 138 315 1.01E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS16590 7c3502ce0aabcee1a153429f1a1c1a62 117 Pfam PF03861 ANTAR domain 45 88 7.1E-7 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS16590 7c3502ce0aabcee1a153429f1a1c1a62 117 Gene3D G3DSA:1.10.10.10 47 89 1.9E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16590 7c3502ce0aabcee1a153429f1a1c1a62 117 SMART SM01012 22 88 1.8E-5 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 4.1E-38 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 4.1E-38 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.1E-38 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 4.1E-38 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 4.1E-38 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 44.569 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 Gene3D G3DSA:3.30.420.10 1 161 6.5E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.5E-61 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 SUPERFAMILY SSF53098 1 158 3.41E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS09660 3d1ef2d6289dd34aef86e029292daac1 189 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 2.9E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MSG_RS17500 885ad446cde01329386fe4bbebbaf747 215 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 37.726 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 MSG_RS17500 885ad446cde01329386fe4bbebbaf747 215 SUPERFAMILY SSF53098 4 178 3.34E-42 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS17500 885ad446cde01329386fe4bbebbaf747 215 Gene3D G3DSA:3.30.420.10 2 179 1.2E-28 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS17500 885ad446cde01329386fe4bbebbaf747 215 SMART SM00479 4 179 1.3E-31 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS17500 885ad446cde01329386fe4bbebbaf747 215 Pfam PF00929 Exonuclease 6 169 5.9E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS22405 16968ff04168f37c55af4c332ff09be9 135 SUPERFAMILY SSF54427 7 127 3.68E-18 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS22405 16968ff04168f37c55af4c332ff09be9 135 Pfam PF12680 SnoaL-like domain 14 112 1.1E-9 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS22405 16968ff04168f37c55af4c332ff09be9 135 Gene3D G3DSA:3.10.450.50 3 134 6.6E-16 T 29-03-2018 MSG_RS17110 a1073da50a0b30594f71b377cfa08bf9 474 SUPERFAMILY SSF53756 3 420 2.42E-77 T 29-03-2018 MSG_RS17110 a1073da50a0b30594f71b377cfa08bf9 474 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 167 397 1.4E-8 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 MSG_RS17110 a1073da50a0b30594f71b377cfa08bf9 474 Gene3D G3DSA:3.40.50.2000 3 262 7.9E-33 T 29-03-2018 MSG_RS17110 a1073da50a0b30594f71b377cfa08bf9 474 Gene3D G3DSA:3.40.50.2000 263 406 2.6E-29 T 29-03-2018 MSG_RS11040 c676015097bb12ce877e2bf61d47cde5 766 Gene3D G3DSA:3.20.20.80 14 678 1.4E-105 T 29-03-2018 MSG_RS11040 c676015097bb12ce877e2bf61d47cde5 766 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 6 762 9.8E-275 T 29-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 MSG_RS11040 c676015097bb12ce877e2bf61d47cde5 766 Pfam PF00128 Alpha amylase, catalytic domain 31 103 4.3E-17 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS11040 c676015097bb12ce877e2bf61d47cde5 766 SUPERFAMILY SSF51445 9 677 2.84E-128 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS11040 c676015097bb12ce877e2bf61d47cde5 766 SMART SM00642 20 412 1.5E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS04925 7dca9c20f64634ec5a7b9b8bb696846c 106 Gene3D G3DSA:1.10.287.1060 9 106 3.4E-6 T 29-03-2018 MSG_RS04925 7dca9c20f64634ec5a7b9b8bb696846c 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 13 105 2.3E-6 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 MSG_RS18580 569647a4540363e2479de333eea68cb4 462 Pfam PF01425 Amidase 27 442 4.5E-98 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS18580 569647a4540363e2479de333eea68cb4 462 SUPERFAMILY SSF75304 5 460 2.09E-115 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS18580 569647a4540363e2479de333eea68cb4 462 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MSG_RS18580 569647a4540363e2479de333eea68cb4 462 Gene3D G3DSA:3.90.1300.10 2 462 2.7E-117 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS15900 d671e3120dcfbafed6bdcb1fa61be726 178 SUPERFAMILY SSF69118 3 172 7.2E-31 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS15900 d671e3120dcfbafed6bdcb1fa61be726 178 Gene3D G3DSA:1.20.1290.10 26 176 1.5E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS15900 d671e3120dcfbafed6bdcb1fa61be726 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 100 3.6E-10 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS20415 8bb3f5a84ff5aec1d125e95ed7f457e4 415 Gene3D G3DSA:3.50.50.60 8 45 0.014 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20415 8bb3f5a84ff5aec1d125e95ed7f457e4 415 Pfam PF16170 Domain of unknown function (DUF4873) 321 411 4.0E-28 T 29-03-2018 IPR032371 Domain of unknown function DUF4873 MSG_RS20415 8bb3f5a84ff5aec1d125e95ed7f457e4 415 Gene3D G3DSA:3.50.50.60 46 107 2.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20415 8bb3f5a84ff5aec1d125e95ed7f457e4 415 SUPERFAMILY SSF51905 17 268 3.05E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20415 8bb3f5a84ff5aec1d125e95ed7f457e4 415 Gene3D G3DSA:3.50.50.60 108 301 4.2E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 Gene3D G3DSA:1.10.287.100 108 140 1.8E-10 T 29-03-2018 MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 SUPERFAMILY SSF46785 4 140 1.32E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 Gene3D G3DSA:1.10.10.10 3 107 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 Pfam PF01047 MarR family 33 90 2.4E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS20745 ec6dd901ab2b8bef368cf22cd34e297b 143 SMART SM00347 25 125 1.0E-26 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Gene3D G3DSA:3.30.300.30 518 623 1.8E-10 T 29-03-2018 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 SUPERFAMILY SSF56801 37 623 5.23E-110 T 29-03-2018 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Pfam PF00501 AMP-binding enzyme 101 522 2.5E-42 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 611 6.0E-6 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 648 5.5E-229 T 29-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 91 7.2E-12 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Gene3D G3DSA:3.40.50.980 273 434 2.8E-21 T 29-03-2018 MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 266 277 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS02825 c4a21bd95661bdc196f0441388cd4f9c 653 Gene3D G3DSA:3.40.50.980 87 272 5.2E-33 T 29-03-2018 MSG_RS18265 27d6fc2d0c206a7bcde7884f20e0958f 169 Hamap MF_01398 ATP synthase subunit b [atpF]. 19 160 11.621 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MSG_RS18265 27d6fc2d0c206a7bcde7884f20e0958f 169 Pfam PF00430 ATP synthase B/B' CF(0) 28 158 1.9E-31 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MSG_RS18265 27d6fc2d0c206a7bcde7884f20e0958f 169 SUPERFAMILY SSF81573 85 143 1.02E-8 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS18265 27d6fc2d0c206a7bcde7884f20e0958f 169 Gene3D G3DSA:1.20.5.620 84 144 3.7E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 SUPERFAMILY SSF53756 4 733 6.73E-201 T 29-03-2018 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Gene3D G3DSA:3.40.50.2000 116 440 3.9E-88 T 29-03-2018 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 PIRSF PIRSF000460 1 822 6.0E-264 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 724 7.0E-233 T 29-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 4.3E-35 T 29-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 613 625 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Pfam PF00343 Carbohydrate phosphorylase 250 432 3.0E-10 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Pfam PF00343 Carbohydrate phosphorylase 543 635 3.3E-9 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Pfam PF00343 Carbohydrate phosphorylase 128 173 3.9E-5 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MSG_RS18115 88c966cf17f03952efd1a36d641fb4ab 879 Gene3D G3DSA:3.40.50.2000 448 774 1.0E-77 T 29-03-2018 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.939 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 PRINTS PR00061 Ribosomal protein L19 signature 33 62 4.2E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 PRINTS PR00061 Ribosomal protein L19 signature 87 112 4.2E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 PRINTS PR00061 Ribosomal protein L19 signature 3 32 4.2E-41 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 PIRSF PIRSF002191 1 113 7.0E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 Pfam PF01245 Ribosomal protein L19 5 112 2.8E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 4.1E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08220 e1269361b23f104cd263f0b4f661af77 113 SUPERFAMILY SSF50104 1 112 2.01E-45 T 29-03-2018 IPR008991 Translation protein SH3-like domain MSG_RS12835 ec57493a6e939b201b2424e69470f83a 164 Pfam PF02577 Bifunctional nuclease 6 127 3.0E-47 T 29-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 MSG_RS12835 ec57493a6e939b201b2424e69470f83a 164 SUPERFAMILY SSF103256 2 136 5.89E-47 T 29-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 MSG_RS02750 2ba4459fd1be0f1c7dcd92166deaaa48 128 Gene3D G3DSA:1.10.1660.10 2 116 9.5E-26 T 29-03-2018 MSG_RS02750 2ba4459fd1be0f1c7dcd92166deaaa48 128 SUPERFAMILY SSF46955 14 105 4.21E-20 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS02750 2ba4459fd1be0f1c7dcd92166deaaa48 128 Pfam PF13411 MerR HTH family regulatory protein 15 80 5.3E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS02750 2ba4459fd1be0f1c7dcd92166deaaa48 128 SMART SM00422 13 82 5.0E-28 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS11295 3af09413b265b1798e4ad73be61f3591 447 SUPERFAMILY SSF55073 240 422 2.35E-60 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS11295 3af09413b265b1798e4ad73be61f3591 447 Gene3D G3DSA:3.30.70.1230 227 424 1.5E-61 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS11295 3af09413b265b1798e4ad73be61f3591 447 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 244 422 2.1E-56 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS11295 3af09413b265b1798e4ad73be61f3591 447 ProSitePatterns PS00452 Guanylate cyclase signature. 355 378 - T 29-03-2018 IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site GO:0009190|GO:0016849|GO:0035556 MSG_RS11295 3af09413b265b1798e4ad73be61f3591 447 SMART SM00044 214 412 2.0E-81 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18765 0e86c226a61d0c768897ed9eaab39515 146 Pfam PF13828 Domain of unknown function (DUF4190) 78 137 1.9E-17 T 29-03-2018 IPR025241 Domain of unknown function DUF4190 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Gene3D G3DSA:1.10.189.10 305 351 4.7E-12 T 29-03-2018 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Gene3D G3DSA:3.50.30.10 354 476 3.5E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 SUPERFAMILY SSF56059 9 341 4.47E-100 T 29-03-2018 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Pfam PF00391 PEP-utilising enzyme, mobile domain 385 453 7.4E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 264 312 8.4E-6 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 24 248 1.1E-33 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 SUPERFAMILY SSF52009 349 459 1.7E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Gene3D G3DSA:3.30.1490.20 10 205 1.0E-40 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS19350 b5141e82a2b538e59c9247b6eac99fdb 538 Gene3D G3DSA:3.30.470.20 206 303 4.0E-19 T 29-03-2018 MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 2.2E-29 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 224 2.1E-50 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 Gene3D G3DSA:1.20.120.450 1 153 6.6E-24 T 29-03-2018 MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 8 257 2.1E-108 T 29-03-2018 IPR017518 Conserved hypothetical protein CHP03084 MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 Pfam PF08608 Wyosine base formation 183 229 2.4E-8 T 29-03-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 MSG_RS00245 97d800e1090a21794972124ffeda60bf 257 SUPERFAMILY SSF109854 1 153 8.01E-35 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 Gene3D G3DSA:3.30.1490.10 76 131 1.0E-19 T 29-03-2018 MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 SUPERFAMILY SSF56047 3 132 1.44E-44 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.426 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 Gene3D G3DSA:3.30.1370.30 1 67 7.0E-26 T 29-03-2018 MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04575 2fd02b0a634e515dd58e9e5dc6242c82 132 Pfam PF00410 Ribosomal protein S8 5 132 2.1E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04805 22827a4adf6cf4398c10b8bfe4a4f892 281 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 21 275 1.7E-113 T 29-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted MSG_RS04805 22827a4adf6cf4398c10b8bfe4a4f892 281 Pfam PF00296 Luciferase-like monooxygenase 22 116 1.1E-11 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04805 22827a4adf6cf4398c10b8bfe4a4f892 281 SUPERFAMILY SSF51679 20 275 1.91E-37 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04805 22827a4adf6cf4398c10b8bfe4a4f892 281 Gene3D G3DSA:3.20.20.30 123 275 2.9E-13 T 29-03-2018 MSG_RS04805 22827a4adf6cf4398c10b8bfe4a4f892 281 Gene3D G3DSA:3.20.20.30 18 122 3.4E-14 T 29-03-2018 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 Gene3D G3DSA:3.50.50.60 1 463 6.1E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 6.4E-5 T 29-03-2018 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 6.4E-5 T 29-03-2018 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 PRINTS PR00419 Adrenodoxin reductase family signature 153 167 6.4E-5 T 29-03-2018 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 SUPERFAMILY SSF51905 2 292 4.75E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 SUPERFAMILY SSF51905 433 463 4.75E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07780 3f71f5798a58d842f8b9b5fc3b34d3eb 484 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 54 1.9E-8 T 29-03-2018 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 Pfam PF00067 Cytochrome P450 186 379 9.5E-27 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 Gene3D G3DSA:1.10.630.10 9 405 8.2E-68 T 29-03-2018 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 325 340 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 91 102 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 155 170 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 280 291 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 199 221 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 346 355 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 138 154 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 297 324 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00359 B-class P450 signature 355 366 5.7E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 SUPERFAMILY SSF48264 17 403 2.49E-88 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00385 P450 superfamily signature 245 262 2.7E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00385 P450 superfamily signature 346 355 2.7E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17840 9188b598ff9d8d0c094258b365c1d5ea 406 PRINTS PR00385 P450 superfamily signature 355 366 2.7E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 334 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 1.0E-42 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 Gene3D G3DSA:3.50.50.60 6 175 1.2E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 Gene3D G3DSA:3.40.30.20 485 557 6.4E-5 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 Gene3D G3DSA:3.30.9.10 176 375 8.5E-37 T 29-03-2018 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 SUPERFAMILY SSF52833 434 560 4.48E-6 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 SUPERFAMILY SSF51905 9 178 1.68E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 SUPERFAMILY SSF51905 270 377 1.68E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01630 65db60276b3e5151c36b018ad29d9082 567 Pfam PF01494 FAD binding domain 9 345 2.4E-82 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 PIRSF PIRSF006468 5 368 5.2E-132 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 50 366 9.5E-145 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 SUPERFAMILY SSF56752 5 364 4.19E-112 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 Pfam PF01063 Amino-transferase class IV 76 323 2.0E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 Gene3D G3DSA:3.20.10.10 188 350 5.5E-51 T 29-03-2018 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 ProSitePatterns PS00770 Aminotransferases class-IV signature. 240 273 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 MSG_RS15385 7d5db497399bc143170a392d16f2523a 368 Gene3D G3DSA:3.30.470.10 1 187 1.1E-65 T 29-03-2018 MSG_RS15295 86cee5e4507c4c72a2f77edb40e360a4 203 SUPERFAMILY SSF81452 12 201 3.66E-55 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS15295 86cee5e4507c4c72a2f77edb40e360a4 203 Gene3D G3DSA:1.20.120.80 19 203 6.2E-55 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS15295 86cee5e4507c4c72a2f77edb40e360a4 203 Pfam PF00510 Cytochrome c oxidase subunit III 22 201 2.3E-26 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS24195 acece8b18573524779835e91a93d8042 303 Pfam PF01040 UbiA prenyltransferase family 38 268 3.0E-20 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MSG_RS11005 0496863d7663397520c11d1c53650384 623 SUPERFAMILY SSF69593 122 298 6.54E-5 T 29-03-2018 MSG_RS11005 0496863d7663397520c11d1c53650384 623 SMART SM00563 117 244 0.0026 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS11005 0496863d7663397520c11d1c53650384 623 PIRSF PIRSF000437 11 623 5.3E-147 T 29-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 MSG_RS11005 0496863d7663397520c11d1c53650384 623 PIRSF PIRSF500064 11 623 1.3E-155 T 29-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 MSG_RS11005 0496863d7663397520c11d1c53650384 623 Gene3D G3DSA:3.40.1130.10 70 326 1.3E-12 T 29-03-2018 MSG_RS11005 0496863d7663397520c11d1c53650384 623 Pfam PF01553 Acyltransferase 112 241 2.6E-7 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS00180 9098d6cd2b0047212b0a0f8c5d3a759a 138 Pfam PF02467 Transcription factor WhiB 12 83 4.2E-12 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS00180 9098d6cd2b0047212b0a0f8c5d3a759a 138 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 88 15.953 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Gene3D G3DSA:3.20.20.60 455 761 1.4E-78 T 29-03-2018 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 PIRSF PIRSF000854 4 754 1.9E-170 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Pfam PF00391 PEP-utilising enzyme, mobile domain 364 435 2.9E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Gene3D G3DSA:3.30.1490.20 5 190 3.0E-47 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 394 405 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 326 5.1E-81 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Gene3D G3DSA:3.30.470.20 191 337 4.2E-37 T 29-03-2018 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Gene3D G3DSA:3.50.30.10 338 454 1.4E-39 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 457 750 3.7E-61 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 SUPERFAMILY SSF51621 461 751 1.33E-75 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 SUPERFAMILY SSF56059 6 363 7.65E-87 T 29-03-2018 MSG_RS13845 10321b1a3c9a15465fd42c5d4a18865a 761 SUPERFAMILY SSF52009 333 441 2.09E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 546 564 5.8E-12 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 387 406 5.8E-12 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 630 646 5.8E-12 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 Gene3D G3DSA:3.40.50.720 373 481 1.1E-19 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 408 3.1E-10 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 546 571 3.1E-10 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 385 653 6.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 Gene3D G3DSA:3.50.50.60 482 654 1.0E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 SUPERFAMILY SSF51395 4 369 6.64E-93 T 29-03-2018 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 340 8.2E-58 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 Gene3D G3DSA:3.20.20.70 3 372 3.4E-105 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 SUPERFAMILY SSF51905 364 498 3.82E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22045 76ac83bcb7a2a32f0caa215a768186b1 684 SUPERFAMILY SSF51905 539 684 3.82E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03525 4e5293aa534b9d94b77c1aab29d2019d 85 SUPERFAMILY SSF46955 31 79 2.38E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS03525 4e5293aa534b9d94b77c1aab29d2019d 85 Gene3D G3DSA:1.10.10.60 5 41 0.0013 T 29-03-2018 MSG_RS03525 4e5293aa534b9d94b77c1aab29d2019d 85 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 31 78 2.7E-19 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MSG_RS03525 4e5293aa534b9d94b77c1aab29d2019d 85 Gene3D G3DSA:1.10.1660.20 42 74 1.7E-11 T 29-03-2018 MSG_RS03525 4e5293aa534b9d94b77c1aab29d2019d 85 Pfam PF12728 Helix-turn-helix domain 31 79 6.6E-14 T 29-03-2018 MSG_RS10570 6b3589a890bb0ae4fe6d1225ec5ae4e3 481 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 25 472 4.7E-216 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MSG_RS10570 6b3589a890bb0ae4fe6d1225ec5ae4e3 481 Pfam PF01458 Uncharacterized protein family (UPF0051) 227 452 1.5E-75 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MSG_RS10570 6b3589a890bb0ae4fe6d1225ec5ae4e3 481 SUPERFAMILY SSF101960 48 478 8.5E-139 T 29-03-2018 MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 383 2.3E-128 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 389 92.614 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 ProSitePatterns PS00618 RecF protein signature 2. 325 343 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 357 2.2E-16 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 SUPERFAMILY SSF52540 3 223 2.02E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 SUPERFAMILY SSF52540 258 346 2.02E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 Gene3D G3DSA:3.40.50.300 2 380 2.4E-26 T 29-03-2018 MSG_RS00015 bf5a0829e3837c6afd3d3bc9a92c3c39 389 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 8.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 257 5.4E-56 T 29-03-2018 MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 Gene3D G3DSA:3.40.50.720 1 258 1.9E-63 T 29-03-2018 MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 SUPERFAMILY SSF51735 17 258 2.95E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22570 f6c83a7f67231e826e0c25f1c7a7c131 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07835 c806e4cb4a10869b427a613bb8d6c551 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 37.331 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MSG_RS07835 c806e4cb4a10869b427a613bb8d6c551 198 Gene3D G3DSA:3.20.19.10 1 168 3.4E-41 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS07835 c806e4cb4a10869b427a613bb8d6c551 198 SUPERFAMILY SSF52016 1 189 1.41E-48 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS07835 c806e4cb4a10869b427a613bb8d6c551 198 Pfam PF00694 Aconitase C-terminal domain 1 117 1.9E-22 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS07835 c806e4cb4a10869b427a613bb8d6c551 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 177 3.1E-50 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MSG_RS03090 1815386c3a4e2bff8a7e4483dfb0f9af 275 Pfam PF08543 Phosphomethylpyrimidine kinase 23 268 5.8E-87 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MSG_RS03090 1815386c3a4e2bff8a7e4483dfb0f9af 275 Gene3D G3DSA:3.40.1190.20 10 270 1.1E-59 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS03090 1815386c3a4e2bff8a7e4483dfb0f9af 275 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 16 269 2.8E-86 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MSG_RS03090 1815386c3a4e2bff8a7e4483dfb0f9af 275 SUPERFAMILY SSF53613 13 272 1.09E-73 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 SUPERFAMILY SSF159127 1 78 5.89E-22 T 29-03-2018 MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 78 5.8E-19 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.3E-12 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 1.3E-12 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 1.3E-12 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 1.3E-12 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS11840 01c905aeeed615e807cf79cbe7edf043 91 Pfam PF01455 HupF/HypC family 1 69 7.0E-25 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS18980 62f4b657f97dcd2fba27257fe21b49ad 337 Gene3D G3DSA:3.40.50.1820 17 320 6.7E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18980 62f4b657f97dcd2fba27257fe21b49ad 337 SUPERFAMILY SSF53474 95 293 2.32E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18980 62f4b657f97dcd2fba27257fe21b49ad 337 Pfam PF07819 PGAP1-like protein 119 173 2.2E-6 T 29-03-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 MSG_RS18950 1457abe1dee76a36ec3d072774ee5843 181 Gene3D G3DSA:3.10.129.10 5 181 3.2E-30 T 29-03-2018 MSG_RS18950 1457abe1dee76a36ec3d072774ee5843 181 Pfam PF13452 N-terminal half of MaoC dehydratase 30 168 1.6E-15 T 29-03-2018 MSG_RS18950 1457abe1dee76a36ec3d072774ee5843 181 SUPERFAMILY SSF54637 25 179 2.94E-16 T 29-03-2018 IPR029069 HotDog domain MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 Gene3D G3DSA:3.30.56.50 24 66 3.1E-4 T 29-03-2018 MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 Pfam PF10150 Ribonuclease E/G family 432 713 3.9E-101 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 SUPERFAMILY SSF50249 353 436 3.13E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 SMART SM00316 351 430 4.7E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 328 741 4.5E-156 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 Gene3D G3DSA:2.40.50.140 347 435 3.1E-26 T 29-03-2018 MSG_RS17155 c3e05ec0cfe50c6a75ac99ee3169483e 928 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 22 68 6.6E-6 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 Pfam PF00582 Universal stress protein family 4 144 1.0E-24 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 SUPERFAMILY SSF52402 2 144 6.7E-30 T 29-03-2018 MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 Gene3D G3DSA:3.40.50.620 1 147 3.6E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 PRINTS PR01438 Universal stress protein signature 4 22 8.1E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 PRINTS PR01438 Universal stress protein signature 122 144 8.1E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS11390 28ad29058fb6d8de5e71feb52d1bb300 147 PRINTS PR01438 Universal stress protein signature 104 116 8.1E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 12 209 2.7E-17 T 29-03-2018 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 Gene3D G3DSA:3.50.50.60 8 165 2.6E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 SUPERFAMILY SSF51905 270 486 1.72E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 SUPERFAMILY SSF51905 6 244 3.18E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 196 1.8E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 300 1.8E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 1.8E-7 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS16820 4ade46c5528d524ed36fdaa2440036fd 500 Gene3D G3DSA:3.50.50.60 166 490 6.8E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19530 b884e5418dedec492b99ee3876b75164 265 Pfam PF01738 Dienelactone hydrolase family 30 261 4.9E-13 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MSG_RS19530 b884e5418dedec492b99ee3876b75164 265 Gene3D G3DSA:3.40.50.1820 1 262 1.9E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19530 b884e5418dedec492b99ee3876b75164 265 SUPERFAMILY SSF53474 17 260 8.25E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 91 107 4.6E-12 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 247 266 4.6E-12 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 298 317 4.6E-12 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 178 196 4.6E-12 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 129 153 4.6E-12 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 Pfam PF02470 MlaD protein 39 112 3.7E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 Gene3D G3DSA:1.20.120.570 134 293 1.4E-4 T 29-03-2018 MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 151 298 7.4E-10 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS21110 229ea3120e1f8e58feeec14ee47c6c7c 360 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 291 2.4E-58 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 Gene3D G3DSA:1.10.1740.10 49 129 1.1E-20 T 29-03-2018 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 52 240 2.1E-105 T 29-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 Pfam PF04542 Sigma-70 region 2 70 132 2.1E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 87 118 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 SUPERFAMILY SSF88946 52 149 8.89E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 Gene3D G3DSA:1.10.10.10 130 231 1.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 SUPERFAMILY SSF88659 172 228 1.87E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 70 227 2.7E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS06160 ddd769bfd349e2c2238ac8b98c3e0db9 249 Pfam PF08281 Sigma-70, region 4 173 224 7.3E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS08585 7a3d5c2026ef759030e2f10d6ee8cdd4 323 SUPERFAMILY SSF56300 14 267 2.37E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS08585 7a3d5c2026ef759030e2f10d6ee8cdd4 323 Gene3D G3DSA:3.60.21.10 14 287 5.7E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS08585 7a3d5c2026ef759030e2f10d6ee8cdd4 323 Pfam PF00149 Calcineurin-like phosphoesterase 15 249 4.5E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 SUPERFAMILY SSF51717 12 280 1.11E-76 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 276 2.2E-86 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 Gene3D G3DSA:3.20.20.20 2 291 9.2E-84 T 29-03-2018 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 Pfam PF00809 Pterin binding enzyme 18 262 8.4E-69 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS18870 ee77bb01c87a2af305794f6343fb1dbf 291 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 SUPERFAMILY SSF56801 45 558 2.09E-103 T 29-03-2018 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Pfam PF00501 AMP-binding enzyme 53 461 5.1E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 546 1.1E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Gene3D G3DSA:3.40.50.980 207 360 4.7E-34 T 29-03-2018 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Gene3D G3DSA:2.30.38.10 374 455 8.5E-4 T 29-03-2018 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Gene3D G3DSA:3.30.300.30 456 558 1.2E-15 T 29-03-2018 MSG_RS18880 d6d042b31adddd7d910cc4ecfe33f647 594 Gene3D G3DSA:3.40.50.980 44 206 4.0E-40 T 29-03-2018 MSG_RS20975 7a244b8e0a1c128a9a0a93bc93fde1f9 375 SUPERFAMILY SSF89796 2 365 1.57E-98 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS20975 7a244b8e0a1c128a9a0a93bc93fde1f9 375 Gene3D G3DSA:3.40.50.10540 1 373 1.6E-100 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS20975 7a244b8e0a1c128a9a0a93bc93fde1f9 375 Pfam PF02515 CoA-transferase family III 5 365 3.1E-74 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS16110 2d90a9a9cb14e061b6ec4382c0908d81 254 Gene3D G3DSA:3.40.190.10 1 247 3.9E-4 T 29-03-2018 MSG_RS16110 2d90a9a9cb14e061b6ec4382c0908d81 254 Pfam PF14032 PknH-like extracellular domain 51 250 8.9E-39 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS15095 8fde74a8b012db194f6ddff86951cf19 486 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 6 358 1.2E-119 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 MSG_RS15095 8fde74a8b012db194f6ddff86951cf19 486 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 317 341 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 MSG_RS15095 8fde74a8b012db194f6ddff86951cf19 486 Pfam PF01098 Cell cycle protein 5 359 6.1E-121 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 5.4E-25 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 271 5.4E-25 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 5.4E-25 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.4E-25 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 223 239 5.4E-25 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 224 238 1.6E-7 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 271 1.6E-7 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-7 T 29-03-2018 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 Gene3D G3DSA:3.30.390.30 309 383 5.0E-7 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 294 1.0E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 SUPERFAMILY SSF55424 306 379 1.65E-7 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 Gene3D G3DSA:3.50.50.60 118 240 2.8E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 Gene3D G3DSA:3.50.50.60 2 117 6.2E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 Gene3D G3DSA:3.50.50.60 241 304 7.8E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06475 c48916a93f79569966f2e93e491f3c39 384 SUPERFAMILY SSF51905 1 302 1.25E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 SUPERFAMILY SSF46689 11 79 2.49E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 Gene3D G3DSA:1.10.10.60 54 177 8.8E-10 T 29-03-2018 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 3.6E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18670 12180effbbd4823d3a229e7788e5e89a 195 Gene3D G3DSA:1.10.10.60 2 53 2.3E-16 T 29-03-2018 MSG_RS08365 eb3a0ae31934b7e5fefbd8b7b3cc805e 304 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 260 286 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MSG_RS08365 eb3a0ae31934b7e5fefbd8b7b3cc805e 304 Pfam PF01148 Cytidylyltransferase family 33 301 9.6E-61 T 29-03-2018 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 ProSitePatterns PS00161 Isocitrate lyase signature. 122 127 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 7 293 47.078 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 SUPERFAMILY SSF51621 5 292 3.27E-96 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 10 292 1.5E-122 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 255 2.4E-52 T 29-03-2018 MSG_RS19320 5a706f15cab26ed4d147fab0e809f3fd 305 Gene3D G3DSA:3.20.20.60 6 296 2.5E-88 T 29-03-2018 MSG_RS00060 c4d92dc582d3bdc215bb6695e6edb7b7 181 SUPERFAMILY SSF46689 12 83 1.08E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00060 c4d92dc582d3bdc215bb6695e6edb7b7 181 Gene3D G3DSA:1.10.260.40 41 113 6.4E-10 T 29-03-2018 MSG_RS00060 c4d92dc582d3bdc215bb6695e6edb7b7 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00060 c4d92dc582d3bdc215bb6695e6edb7b7 181 Gene3D G3DSA:1.10.10.60 1 40 1.3E-10 T 29-03-2018 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 24 256 29.269 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 258 1.7E-80 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 54 71 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 260 34.467 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 Gene3D G3DSA:3.20.20.70 3 267 2.1E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11225 6a2da2ebc933c4367b65c21c4be6d284 272 SUPERFAMILY SSF51366 15 260 6.44E-80 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS23805 2be900f8cac59b2161b706c329d98e8f 323 SUPERFAMILY SSF48179 179 272 7.25E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS23805 2be900f8cac59b2161b706c329d98e8f 323 SUPERFAMILY SSF51735 10 173 1.9E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23805 2be900f8cac59b2161b706c329d98e8f 323 Pfam PF02153 Prephenate dehydrogenase 31 264 2.6E-42 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MSG_RS23805 2be900f8cac59b2161b706c329d98e8f 323 Gene3D G3DSA:1.10.3660.10 185 307 7.5E-12 T 29-03-2018 MSG_RS23805 2be900f8cac59b2161b706c329d98e8f 323 Gene3D G3DSA:3.40.50.720 3 183 1.2E-25 T 29-03-2018 MSG_RS08270 a619221268e81aa3165f246cf4845057 79 Gene3D G3DSA:3.90.820.10 3 69 1.3E-33 T 29-03-2018 MSG_RS08270 a619221268e81aa3165f246cf4845057 79 SMART SM00923 4 54 1.4E-30 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS08270 a619221268e81aa3165f246cf4845057 79 Pfam PF03621 MbtH-like protein 4 54 2.1E-27 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS08270 a619221268e81aa3165f246cf4845057 79 SUPERFAMILY SSF160582 3 70 5.89E-30 T 29-03-2018 MSG_RS23665 a4c8ab7a8433fd71944c96ce5b256398 164 Pfam PF04008 Adenosine specific kinase 10 163 8.1E-73 T 29-03-2018 IPR007153 Adenosine specific kinase MSG_RS23665 a4c8ab7a8433fd71944c96ce5b256398 164 SUPERFAMILY SSF103165 6 164 2.22E-70 T 29-03-2018 IPR007153 Adenosine specific kinase MSG_RS23665 a4c8ab7a8433fd71944c96ce5b256398 164 Gene3D G3DSA:3.40.1520.10 5 163 1.1E-75 T 29-03-2018 IPR007153 Adenosine specific kinase MSG_RS10820 5488293459807d7cc17af2faef294991 360 Gene3D G3DSA:3.40.50.150 103 317 3.4E-18 T 29-03-2018 MSG_RS10820 5488293459807d7cc17af2faef294991 360 Pfam PF13489 Methyltransferase domain 138 288 7.3E-14 T 29-03-2018 MSG_RS10820 5488293459807d7cc17af2faef294991 360 SUPERFAMILY SSF53335 133 305 4.18E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 6.2E-29 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 Gene3D G3DSA:1.10.287.990 21 84 4.9E-15 T 29-03-2018 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 SUPERFAMILY SSF54719 84 197 6.02E-37 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 SUPERFAMILY SSF46609 3 88 2.23E-28 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 4.4E-26 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PIRSF PIRSF000349 1 201 1.3E-65 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 4.0E-18 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 4.0E-18 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 4.0E-18 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 4.0E-18 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS01430 cadc56a309dcacd180cf5abf00abbd7c 215 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 4.0E-18 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 Pfam PF12849 PBP superfamily domain 50 338 8.9E-56 T 29-03-2018 IPR024370 PBP domain MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 Gene3D G3DSA:3.40.190.10 51 221 4.3E-33 T 29-03-2018 MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 Gene3D G3DSA:3.40.190.10 231 372 4.1E-15 T 29-03-2018 MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 SUPERFAMILY SSF53850 51 372 1.59E-85 T 29-03-2018 MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 PIRSF PIRSF002756 9 372 1.0E-111 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS20485 d88781c5d547f46c1df3ef0156ac4b05 372 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 52 371 4.4E-113 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 158 173 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 354 365 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 94 105 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 141 157 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 278 289 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 296 323 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 324 339 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 195 217 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00359 B-class P450 signature 345 354 1.3E-52 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00385 P450 superfamily signature 241 258 3.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00385 P450 superfamily signature 345 354 3.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00385 P450 superfamily signature 354 365 3.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 PRINTS PR00385 P450 superfamily signature 278 289 3.0E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 Pfam PF00067 Cytochrome P450 209 374 1.1E-25 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 SUPERFAMILY SSF48264 25 404 1.83E-87 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS14520 b0652296a86337099924a495efe05e90 404 Gene3D G3DSA:1.10.630.10 22 404 3.3E-67 T 29-03-2018 MSG_RS23425 51b56fd8d6b46dc1a0b1e3eb335c5c9c 415 Pfam PF08353 Domain of unknown function (DUF1727) 302 404 7.0E-25 T 29-03-2018 IPR013564 Domain of unknown function DUF1727 MSG_RS23425 51b56fd8d6b46dc1a0b1e3eb335c5c9c 415 Gene3D G3DSA:3.40.1190.10 44 284 5.1E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS23425 51b56fd8d6b46dc1a0b1e3eb335c5c9c 415 SUPERFAMILY SSF53623 48 191 5.89E-32 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS23425 51b56fd8d6b46dc1a0b1e3eb335c5c9c 415 SUPERFAMILY SSF53623 224 277 5.89E-32 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS23425 51b56fd8d6b46dc1a0b1e3eb335c5c9c 415 Pfam PF08245 Mur ligase middle domain 56 263 7.3E-14 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 2.1E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 Gene3D G3DSA:1.10.10.10 135 217 2.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 Pfam PF00072 Response regulator receiver domain 12 123 3.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 SMART SM00448 10 123 7.6E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 SMART SM00421 153 210 2.9E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 SUPERFAMILY SSF52172 9 135 3.42E-32 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 Gene3D G3DSA:3.40.50.2300 9 134 4.0E-33 T 29-03-2018 MSG_RS21490 092a8556d110feccd12f47c2b7188868 217 SUPERFAMILY SSF46894 144 216 2.18E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS07615 4da3ea794e622d557eb68c4a23da365d 414 Pfam PF13439 Glycosyltransferase Family 4 15 204 5.8E-26 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS07615 4da3ea794e622d557eb68c4a23da365d 414 SUPERFAMILY SSF53756 1 390 1.95E-90 T 29-03-2018 MSG_RS07615 4da3ea794e622d557eb68c4a23da365d 414 Gene3D G3DSA:3.40.50.2000 205 378 4.2E-44 T 29-03-2018 MSG_RS07615 4da3ea794e622d557eb68c4a23da365d 414 Pfam PF00534 Glycosyl transferases group 1 213 372 7.6E-42 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS07615 4da3ea794e622d557eb68c4a23da365d 414 Gene3D G3DSA:3.40.50.2000 1 204 2.4E-21 T 29-03-2018 MSG_RS17075 8581e5e6d49125e45f9dfb5a0d203515 186 SUPERFAMILY SSF52016 5 163 1.29E-35 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS17075 8581e5e6d49125e45f9dfb5a0d203515 186 Gene3D G3DSA:3.20.19.10 1 164 4.1E-31 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS17075 8581e5e6d49125e45f9dfb5a0d203515 186 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 7 155 1.1E-38 T 29-03-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 MSG_RS17075 8581e5e6d49125e45f9dfb5a0d203515 186 Pfam PF00694 Aconitase C-terminal domain 54 107 4.1E-8 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS24405 ce7345cba4daad06ed7073ad81fe667b 282 Pfam PF00296 Luciferase-like monooxygenase 10 229 2.0E-48 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS24405 ce7345cba4daad06ed7073ad81fe667b 282 Gene3D G3DSA:3.20.20.30 1 279 3.8E-65 T 29-03-2018 MSG_RS24405 ce7345cba4daad06ed7073ad81fe667b 282 SUPERFAMILY SSF51679 2 253 6.33E-62 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS24405 ce7345cba4daad06ed7073ad81fe667b 282 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 3 227 9.4E-91 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c MSG_RS03895 9b32dc98dee75fd24cf774f6ace6e08d 160 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 37 157 4.5E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MSG_RS03895 9b32dc98dee75fd24cf774f6ace6e08d 160 Gene3D G3DSA:2.170.150.20 27 160 1.9E-57 T 29-03-2018 MSG_RS03895 9b32dc98dee75fd24cf774f6ace6e08d 160 Pfam PF01641 SelR domain 41 158 5.0E-50 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MSG_RS03895 9b32dc98dee75fd24cf774f6ace6e08d 160 SUPERFAMILY SSF51316 36 159 1.99E-55 T 29-03-2018 IPR011057 Mss4-like MSG_RS12575 5f8fcc4fbbef5ac7cfa52696124fa8be 454 Pfam PF06974 Protein of unknown function (DUF1298) 313 449 4.8E-17 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS12575 5f8fcc4fbbef5ac7cfa52696124fa8be 454 Gene3D G3DSA:3.30.559.10 3 177 1.4E-6 T 29-03-2018 MSG_RS12575 5f8fcc4fbbef5ac7cfa52696124fa8be 454 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 6 273 3.1E-41 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS12575 5f8fcc4fbbef5ac7cfa52696124fa8be 454 SUPERFAMILY SSF52777 255 442 2.0E-6 T 29-03-2018 MSG_RS12575 5f8fcc4fbbef5ac7cfa52696124fa8be 454 SUPERFAMILY SSF52777 23 168 5.45E-10 T 29-03-2018 MSG_RS13175 5bd283104f529dc3f54c6b57234bc3c5 152 Pfam PF12680 SnoaL-like domain 15 116 1.0E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS13175 5bd283104f529dc3f54c6b57234bc3c5 152 Gene3D G3DSA:3.10.450.50 2 145 4.6E-18 T 29-03-2018 MSG_RS13175 5bd283104f529dc3f54c6b57234bc3c5 152 SUPERFAMILY SSF54427 10 130 7.39E-23 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS00825 deabe6d513aa34b0bd01108d01c0cc69 268 Pfam PF14494 Domain of unknown function (DUF4436) 13 255 2.8E-80 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 SUPERFAMILY SSF55931 106 477 5.49E-137 T 29-03-2018 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 265 280 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 SMART SM01230 105 387 1.4E-146 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 Pfam PF00120 Glutamine synthetase, catalytic domain 106 475 9.2E-134 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 Gene3D G3DSA:3.30.590.10 108 460 1.0E-122 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 394 406 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 Gene3D G3DSA:3.10.20.70 5 107 3.3E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 477 2.5E-204 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 4.9E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS15455 f845a87e5b2445bcd6dbe616b38b53ec 478 SUPERFAMILY SSF54368 5 103 3.79E-33 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS04180 4990754e4769b27f674c5f47fea41523 207 SUPERFAMILY SSF160369 1 169 3.14E-49 T 29-03-2018 MSG_RS04180 4990754e4769b27f674c5f47fea41523 207 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.547 T 29-03-2018 IPR022973 Ribosomal protein L10 MSG_RS04180 4990754e4769b27f674c5f47fea41523 207 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 60 169 0.003 T 29-03-2018 MSG_RS04180 4990754e4769b27f674c5f47fea41523 207 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04180 4990754e4769b27f674c5f47fea41523 207 Pfam PF00466 Ribosomal protein L10 1 98 2.3E-25 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MSG_RS21575 69db15d35bde9df589208b8083d2048a 231 Pfam PF01427 D-ala-D-ala dipeptidase 38 230 2.6E-65 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MSG_RS21575 69db15d35bde9df589208b8083d2048a 231 SUPERFAMILY SSF55166 39 221 1.88E-47 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MSG_RS21575 69db15d35bde9df589208b8083d2048a 231 Gene3D G3DSA:3.30.1380.10 37 231 8.4E-40 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MSG_RS21575 69db15d35bde9df589208b8083d2048a 231 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 40 229 25.16 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MSG_RS21575 69db15d35bde9df589208b8083d2048a 231 PIRSF PIRSF026671 11 224 8.8E-51 T 29-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MSG_RS10465 1145451ccdd10febd26901768fdc4488 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 4.6E-5 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MSG_RS10465 1145451ccdd10febd26901768fdc4488 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 4.6E-5 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MSG_RS10465 1145451ccdd10febd26901768fdc4488 77 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 4.6E-5 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MSG_RS10465 1145451ccdd10febd26901768fdc4488 77 Pfam PF03840 Preprotein translocase SecG subunit 5 72 9.3E-16 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MSG_RS10465 1145451ccdd10febd26901768fdc4488 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 72 6.3E-19 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 Gene3D G3DSA:3.40.1050.10 1 204 9.9E-60 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 SUPERFAMILY SSF53056 3 199 1.57E-53 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 51 58 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 Pfam PF00484 Carbonic anhydrase 46 193 7.6E-39 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 SMART SM00947 39 198 5.5E-48 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS22760 78e53d9d81ce76980f2b57acd7b80f45 205 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 88 108 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MSG_RS07710 57b9c37a835f62e37442b8cff6a35e9a 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.9E-30 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MSG_RS07710 57b9c37a835f62e37442b8cff6a35e9a 99 SUPERFAMILY SSF141000 3 94 6.02E-27 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MSG_RS07710 57b9c37a835f62e37442b8cff6a35e9a 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.798 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MSG_RS07710 57b9c37a835f62e37442b8cff6a35e9a 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.1E-16 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 SUPERFAMILY SSF54197 1 132 3.26E-37 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 Pfam PF01230 HIT domain 11 106 2.1E-26 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 29-03-2018 IPR019808 Histidine triad, conserved site MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 Gene3D G3DSA:3.30.428.10 1 142 1.2E-34 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 PRINTS PR00332 Histidine triad family signature 25 43 2.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 PRINTS PR00332 Histidine triad family signature 92 102 2.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS18585 fde5f9f6b6401b7e2e56a94fe01c018f 142 PRINTS PR00332 Histidine triad family signature 4 20 2.8E-15 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 224 2.0E-69 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 PIRSF PIRSF000386 1 228 2.4E-85 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 228 95.656 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 SUPERFAMILY SSF75217 1 226 3.66E-83 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 Gene3D G3DSA:3.40.1280.10 1 170 1.3E-66 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 226 7.7E-69 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MSG_RS08210 981e9882472caabc6f78a39da890b4ed 228 Gene3D G3DSA:1.10.1270.20 171 228 4.0E-26 T 29-03-2018 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 SUPERFAMILY SSF46689 31 114 8.74E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 Gene3D G3DSA:1.10.10.60 2 88 5.2E-21 T 29-03-2018 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 Gene3D G3DSA:1.10.357.10 89 223 1.3E-18 T 29-03-2018 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 90 2.3E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06245 5870d36aa121adfb55757b82a6964791 228 SUPERFAMILY SSF48498 110 222 5.69E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 SUPERFAMILY SSF48264 11 389 2.49E-90 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 Gene3D G3DSA:1.10.630.10 2 405 1.6E-70 T 29-03-2018 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 Pfam PF00067 Cytochrome P450 199 363 7.4E-21 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 145 160 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 282 309 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 128 144 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 341 352 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 184 206 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 265 276 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 82 93 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS18925 264c4af4a7e7ea7b5d6e7625d3da5bb7 417 PRINTS PR00359 B-class P450 signature 332 341 2.7E-42 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS06770 a456338a16991548fbaee391d0757346 338 Pfam PF00083 Sugar (and other) transporter 3 206 2.9E-20 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MSG_RS06770 a456338a16991548fbaee391d0757346 338 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS06770 a456338a16991548fbaee391d0757346 338 Gene3D G3DSA:1.20.1250.20 206 325 6.1E-10 T 29-03-2018 MSG_RS06770 a456338a16991548fbaee391d0757346 338 Gene3D G3DSA:1.20.1250.20 1 205 4.2E-18 T 29-03-2018 MSG_RS06770 a456338a16991548fbaee391d0757346 338 SUPERFAMILY SSF103473 2 322 1.83E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06770 a456338a16991548fbaee391d0757346 338 ProSitePatterns PS00216 Sugar transport proteins signature 1. 276 292 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 Gene3D G3DSA:2.60.120.260 1037 1203 1.5E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 407 426 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 197 218 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 95 111 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 76 95 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 173 197 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 PRINTS PR01806 Virulence factor MviN signature 309 335 1.4E-14 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 Gene3D G3DSA:3.30.200.20 726 852 1.2E-4 T 29-03-2018 MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 Pfam PF03023 MviN-like protein 72 544 3.2E-118 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MSG_RS24645 c6ef633a4c864b511cb880349a8cd76f 1207 SUPERFAMILY SSF56112 745 902 3.58E-6 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS11070 c65d2762b295da84cfce785b19fb5868 386 Pfam PF00155 Aminotransferase class I and II 43 373 5.3E-57 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS11070 c65d2762b295da84cfce785b19fb5868 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MSG_RS11070 c65d2762b295da84cfce785b19fb5868 386 SUPERFAMILY SSF53383 31 381 6.53E-87 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS11070 c65d2762b295da84cfce785b19fb5868 386 Gene3D G3DSA:3.90.1150.10 283 386 6.4E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS11070 c65d2762b295da84cfce785b19fb5868 386 Gene3D G3DSA:3.40.640.10 50 282 5.6E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.6E-26 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 Gene3D G3DSA:3.30.70.60 1 96 1.2E-28 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 SUPERFAMILY SSF54995 1 95 3.53E-32 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.662 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MSG_RS00375 b7dbabed52a79f7c6382b8f8ce6f9d51 96 Pfam PF01250 Ribosomal protein S6 4 92 7.0E-28 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 227 246 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 Gene3D G3DSA:3.40.640.10 41 292 1.5E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 SUPERFAMILY SSF53383 8 414 3.16E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 Gene3D G3DSA:3.90.1150.10 293 419 4.1E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 11 418 1.9E-168 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MSG_RS10585 1d97c3fc390de0ebc9bd49bb0e4577ab 420 Pfam PF00266 Aminotransferase class-V 31 406 8.6E-136 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS23120 ac6ee05f92b89169e3492cd36c46962a 211 Gene3D G3DSA:3.40.30.10 29 209 2.7E-19 T 29-03-2018 MSG_RS23120 ac6ee05f92b89169e3492cd36c46962a 211 Pfam PF08534 Redoxin 80 196 8.7E-13 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MSG_RS23120 ac6ee05f92b89169e3492cd36c46962a 211 SUPERFAMILY SSF52833 86 195 1.78E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS23120 ac6ee05f92b89169e3492cd36c46962a 211 ProSitePatterns PS00194 Thioredoxin family active site. 103 121 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Pfam PF00391 PEP-utilising enzyme, mobile domain 762 833 1.5E-19 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Gene3D G3DSA:3.30.1490.20 56 144 2.7E-15 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Gene3D G3DSA:3.30.1490.20 1 55 8.0E-4 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 72 280 6.0E-49 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Gene3D G3DSA:3.30.470.20 145 289 4.3E-29 T 29-03-2018 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 Gene3D G3DSA:3.50.30.10 728 837 2.2E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 SUPERFAMILY SSF56059 9 287 7.53E-57 T 29-03-2018 MSG_RS18625 7e270db29778f2f7dc313e1a93ed4f3e 842 SUPERFAMILY SSF52009 736 838 2.62E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MSG_RS15185 2e883a550bcdbafbe9fc84d997831cdb 298 Gene3D G3DSA:3.20.20.220 2 288 1.0E-18 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MSG_RS15185 2e883a550bcdbafbe9fc84d997831cdb 298 SUPERFAMILY SSF51730 148 207 5.89E-5 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MSG_RS00780 64a72f16f1d8bd54d48960d0dca51b9f 190 SUPERFAMILY SSF81342 9 183 1.26E-26 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MSG_RS00780 64a72f16f1d8bd54d48960d0dca51b9f 190 Gene3D G3DSA:1.20.950.20 6 188 5.6E-26 T 29-03-2018 MSG_RS00780 64a72f16f1d8bd54d48960d0dca51b9f 190 Pfam PF01292 Prokaryotic cytochrome b561 14 180 3.1E-18 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 Gene3D G3DSA:3.40.50.620 1 206 1.1E-54 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 2 353 5.0E-85 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 354 35.832 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 Gene3D G3DSA:2.30.30.280 208 272 6.3E-16 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 SUPERFAMILY SSF52402 2 238 1.65E-45 T 29-03-2018 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 Pfam PF03054 tRNA methyl transferase 2 353 9.2E-115 T 29-03-2018 MSG_RS07655 26d79dd5902e97d70076df57fe729e1d 358 Gene3D G3DSA:2.40.30.10 273 358 4.3E-19 T 29-03-2018 MSG_RS00755 59d958ed4f01327b4dccaab6ab156b82 201 SUPERFAMILY SSF53335 42 189 1.08E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS00755 59d958ed4f01327b4dccaab6ab156b82 201 Gene3D G3DSA:3.40.50.150 9 197 3.1E-30 T 29-03-2018 MSG_RS00755 59d958ed4f01327b4dccaab6ab156b82 201 Pfam PF08241 Methyltransferase domain 56 155 2.2E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS21650 f83c992594d1df0baea14e5224ea0786 203 Gene3D G3DSA:1.10.357.10 14 201 4.2E-23 T 29-03-2018 MSG_RS21650 f83c992594d1df0baea14e5224ea0786 203 SUPERFAMILY SSF46689 17 86 1.85E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 125 1.9E-29 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Gene3D G3DSA:3.30.310.50 370 459 3.8E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 SUPERFAMILY SSF53738 11 127 2.79E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 SUPERFAMILY SSF53738 158 260 6.67E-27 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Gene3D G3DSA:3.40.120.10 165 277 8.1E-30 T 29-03-2018 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Gene3D G3DSA:3.40.120.10 278 369 1.1E-25 T 29-03-2018 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Gene3D G3DSA:3.40.120.10 7 164 2.9E-30 T 29-03-2018 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 454 1.8E-12 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 259 4.4E-22 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 SUPERFAMILY SSF53738 265 369 1.18E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 1.0E-21 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 223 1.0E-21 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 1.0E-21 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 1.0E-21 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 270 373 1.7E-24 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS05850 92fea81f800e2ca40980ff612489bf03 465 SUPERFAMILY SSF55957 374 456 5.36E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MSG_RS10475 67d949c4e9acecc8bbf832a660313c61 268 Pfam PF06724 Domain of Unknown Function (DUF1206) 197 264 3.4E-17 T 29-03-2018 IPR009597 Domain of unknown function DUF1206 MSG_RS10475 67d949c4e9acecc8bbf832a660313c61 268 Pfam PF06724 Domain of Unknown Function (DUF1206) 23 89 1.3E-17 T 29-03-2018 IPR009597 Domain of unknown function DUF1206 MSG_RS10475 67d949c4e9acecc8bbf832a660313c61 268 Pfam PF06724 Domain of Unknown Function (DUF1206) 111 176 6.1E-12 T 29-03-2018 IPR009597 Domain of unknown function DUF1206 MSG_RS14795 eb07af2348b6fae6112cb5afe690c344 288 Gene3D G3DSA:3.90.320.10 1 205 6.6E-24 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MSG_RS14795 eb07af2348b6fae6112cb5afe690c344 288 Pfam PF12705 PD-(D/E)XK nuclease superfamily 13 259 4.4E-39 T 29-03-2018 MSG_RS14795 eb07af2348b6fae6112cb5afe690c344 288 SUPERFAMILY SSF52980 36 193 1.13E-7 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MSG_RS21880 0cd19cb00a727fa6e0beb00c8d6ee4ca 156 SUPERFAMILY SSF51182 24 149 1.53E-18 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS21880 0cd19cb00a727fa6e0beb00c8d6ee4ca 156 Pfam PF07883 Cupin domain 67 132 9.7E-9 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MSG_RS21880 0cd19cb00a727fa6e0beb00c8d6ee4ca 156 Gene3D G3DSA:2.60.120.10 6 155 1.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS03490 f572a8a78ccd7efaf1a04986eec374b3 161 SUPERFAMILY SSF55811 10 142 2.03E-30 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS03490 f572a8a78ccd7efaf1a04986eec374b3 161 Gene3D G3DSA:3.90.79.10 1 151 2.8E-29 T 29-03-2018 MSG_RS03490 f572a8a78ccd7efaf1a04986eec374b3 161 Pfam PF00293 NUDIX domain 23 138 2.5E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS03490 f572a8a78ccd7efaf1a04986eec374b3 161 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS10175 b5769f925b660084ef0a776e41904a98 246 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10175 b5769f925b660084ef0a776e41904a98 246 Pfam PF00005 ABC transporter 23 161 1.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10175 b5769f925b660084ef0a776e41904a98 246 SMART SM00382 31 211 1.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10175 b5769f925b660084ef0a776e41904a98 246 SUPERFAMILY SSF52540 7 235 4.09E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10175 b5769f925b660084ef0a776e41904a98 246 Gene3D G3DSA:3.40.50.300 3 218 9.3E-60 T 29-03-2018 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 Gene3D G3DSA:3.30.70.20 1 64 7.5E-9 T 29-03-2018 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 2.6E-14 T 29-03-2018 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.2E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS21410 06390df66bbdf1de3e5c03c0e6283582 64 SUPERFAMILY SSF54862 2 63 3.36E-13 T 29-03-2018 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 SUPERFAMILY SSF46689 3 79 9.45E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 7.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 7.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.7E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 Gene3D G3DSA:1.10.10.60 2 53 3.8E-20 T 29-03-2018 MSG_RS23780 3b4228c2da9dd70060debdd5f9304ad7 190 Gene3D G3DSA:1.10.357.10 54 188 1.2E-17 T 29-03-2018 MSG_RS18595 160139352e16374bb5afa1fc306e63fa 343 SUPERFAMILY SSF51679 2 318 9.16E-71 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS18595 160139352e16374bb5afa1fc306e63fa 343 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 340 6.1E-115 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 MSG_RS18595 160139352e16374bb5afa1fc306e63fa 343 Pfam PF00296 Luciferase-like monooxygenase 10 304 1.3E-37 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS18595 160139352e16374bb5afa1fc306e63fa 343 Gene3D G3DSA:3.20.20.30 1 343 2.1E-68 T 29-03-2018 MSG_RS00510 b1b817eda54d80628cd874c5012fc099 452 SUPERFAMILY SSF52777 55 154 6.56E-8 T 29-03-2018 MSG_RS00510 b1b817eda54d80628cd874c5012fc099 452 Pfam PF06974 Protein of unknown function (DUF1298) 300 446 1.6E-28 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS00510 b1b817eda54d80628cd874c5012fc099 452 Gene3D G3DSA:3.30.559.10 3 156 1.2E-8 T 29-03-2018 MSG_RS00510 b1b817eda54d80628cd874c5012fc099 452 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 260 9.8E-80 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS00510 b1b817eda54d80628cd874c5012fc099 452 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 448 3.4E-141 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 Pfam PF07728 AAA domain (dynein-related subfamily) 32 166 2.9E-12 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 SUPERFAMILY SSF52540 2 296 5.32E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 Gene3D G3DSA:3.40.50.300 1 173 1.3E-19 T 29-03-2018 MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 SMART SM00327 431 604 7.5E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 Gene3D G3DSA:1.10.8.80 218 306 2.1E-26 T 29-03-2018 MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 Pfam PF13519 von Willebrand factor type A domain 434 540 8.4E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 SMART SM00382 27 176 2.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 SUPERFAMILY SSF53300 434 589 1.47E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS08480 a6db6fe72e6ec64fd935092b5d9d5ae1 611 Gene3D G3DSA:3.40.50.410 425 575 3.1E-24 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS00120 9b6eefe3147a8840349b09ece2bc412d 503 Pfam PF13672 Protein phosphatase 2C 18 198 2.1E-13 T 29-03-2018 MSG_RS00120 9b6eefe3147a8840349b09ece2bc412d 503 Gene3D G3DSA:3.60.40.10 5 235 1.3E-39 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00120 9b6eefe3147a8840349b09ece2bc412d 503 SUPERFAMILY SSF81606 4 234 8.11E-64 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00120 9b6eefe3147a8840349b09ece2bc412d 503 SMART SM00331 11 235 3.8E-55 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00120 9b6eefe3147a8840349b09ece2bc412d 503 SMART SM00332 2 233 3.3E-34 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 SUPERFAMILY SSF53901 297 446 7.09E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 Pfam PF02803 Thiolase, C-terminal domain 298 446 1.6E-28 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 Pfam PF00108 Thiolase, N-terminal domain 22 290 2.5E-41 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 Gene3D G3DSA:3.40.47.10 302 445 5.0E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 ProSitePatterns PS00099 Thiolases active site. 429 442 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 PIRSF PIRSF000429 17 447 2.0E-97 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 24 446 4.0E-119 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 Gene3D G3DSA:3.40.47.10 14 301 4.8E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS02175 eb129c7401f6ecba184713d976376302 447 SUPERFAMILY SSF53901 22 297 4.76E-53 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS06330 c163ec03ad75e42e724e4489830a0846 451 SUPERFAMILY SSF55486 70 422 4.61E-110 T 29-03-2018 MSG_RS06330 c163ec03ad75e42e724e4489830a0846 451 Pfam PF10103 Zincin-like metallopeptidase 71 419 2.5E-111 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 MSG_RS06330 c163ec03ad75e42e724e4489830a0846 451 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 71 422 1.5E-121 T 29-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 MSG_RS10420 7b076df51a3ff3e43726b54dea6c854f 462 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 459 7.9E-150 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS10420 7b076df51a3ff3e43726b54dea6c854f 462 Pfam PF06974 Protein of unknown function (DUF1298) 306 455 8.0E-32 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS10420 7b076df51a3ff3e43726b54dea6c854f 462 Gene3D G3DSA:3.30.559.10 6 276 2.1E-6 T 29-03-2018 MSG_RS10420 7b076df51a3ff3e43726b54dea6c854f 462 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 265 1.4E-83 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS10420 7b076df51a3ff3e43726b54dea6c854f 462 SUPERFAMILY SSF52777 4 155 1.22E-9 T 29-03-2018 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 364 495 4.9E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 483 502 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 322 336 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 466 483 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 362 377 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 445 457 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 414 433 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 553 565 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 PRINTS PR00819 CbxX/CfqX superfamily signature 400 414 3.3E-54 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 SUPERFAMILY SSF52540 314 532 1.89E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 Gene3D G3DSA:1.25.40.10 44 205 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 53 603 5.9E-241 T 29-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 SUPERFAMILY SSF48452 195 272 1.38E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 SUPERFAMILY SSF48452 125 158 1.38E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 SMART SM00382 359 498 3.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 Gene3D G3DSA:1.25.40.10 206 274 0.0014 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11595 089614a3efcd482cdc8f69c8a09dcaed 613 Gene3D G3DSA:3.40.50.300 305 495 5.5E-25 T 29-03-2018 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 245 271 7.4E-8 T 29-03-2018 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 178 201 7.4E-8 T 29-03-2018 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 127 141 7.4E-8 T 29-03-2018 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 PIRSF PIRSF000310 1 350 2.1E-89 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 Gene3D G3DSA:4.10.480.10 228 299 6.0E-28 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 Gene3D G3DSA:3.40.50.700 7 227 2.1E-42 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 SUPERFAMILY SSF56770 15 300 2.75E-64 T 29-03-2018 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 198 1.2E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14005 5dddc7aa89f9631356e006fc557b30fe 351 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 221 299 1.2E-24 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MSG_RS14550 99a22f71e1781e8627514bc94c67cf08 264 Gene3D G3DSA:3.90.550.10 3 258 9.7E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS14550 99a22f71e1781e8627514bc94c67cf08 264 Pfam PF00535 Glycosyl transferase family 2 21 186 6.5E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS14550 99a22f71e1781e8627514bc94c67cf08 264 SUPERFAMILY SSF53448 19 248 1.78E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.2E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 SUPERFAMILY SSF52172 1 179 2.18E-28 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 6.6E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 Gene3D G3DSA:3.40.50.2300 1 126 4.5E-29 T 29-03-2018 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 SMART SM00448 2 115 1.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 Gene3D G3DSA:1.10.10.10 127 209 1.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 SMART SM00421 147 204 6.5E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS13895 dc91b02f492d778d1a681f446f93f7bd 218 Pfam PF00072 Response regulator receiver domain 4 116 1.6E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS00885 69dc7ca7a8af12262354f9a95a7a7e27 241 Gene3D G3DSA:1.10.472.50 57 210 2.5E-5 T 29-03-2018 MSG_RS00885 69dc7ca7a8af12262354f9a95a7a7e27 241 SUPERFAMILY SSF109604 75 157 2.79E-8 T 29-03-2018 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 284 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 17 438 95.936 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 Pfam PF00202 Aminotransferase class-III 47 431 4.3E-94 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 SUPERFAMILY SSF53383 16 434 5.84E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 Gene3D G3DSA:3.90.1150.10 317 446 1.5E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 Gene3D G3DSA:3.40.640.10 73 316 2.9E-67 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS03675 0ca70ded8a8b0fbbc44ebfc5a70fda6b 446 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 18 431 2.1E-187 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MSG_RS09805 b54197f271d71ad9a2ab85217f8feb08 144 SUPERFAMILY SSF50475 33 136 3.34E-8 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS09805 b54197f271d71ad9a2ab85217f8feb08 144 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 1.9E-31 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS09805 b54197f271d71ad9a2ab85217f8feb08 144 Pfam PF04075 F420H(2)-dependent quinone reductase 20 139 4.3E-40 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS09805 b54197f271d71ad9a2ab85217f8feb08 144 Gene3D G3DSA:2.30.110.10 7 144 6.6E-43 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 9.0E-19 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 176 1.2E-85 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 101 172 9.6E-14 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 Gene3D G3DSA:1.20.1290.10 1 177 7.2E-46 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 178 82.322 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13115 9db23e54c712e0ac3c5ca7d53f59b44f 178 SUPERFAMILY SSF69118 3 174 8.51E-50 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 Gene3D G3DSA:3.30.420.40 169 327 3.9E-17 T 29-03-2018 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 Pfam PF00012 Hsp70 protein 163 346 5.7E-16 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 PRINTS PR00301 70kDa heat shock protein signature 299 315 5.0E-5 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 PRINTS PR00301 70kDa heat shock protein signature 330 350 5.0E-5 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 PRINTS PR00301 70kDa heat shock protein signature 7 20 5.0E-5 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 Gene3D G3DSA:3.30.420.40 6 168 5.9E-4 T 29-03-2018 MSG_RS15825 33c9f1f3ac676bfdf3d87d912bb0f2ea 597 SUPERFAMILY SSF53067 163 345 1.09E-28 T 29-03-2018 MSG_RS08780 a6e10403d5499267bbb69e1112980e4c 406 Pfam PF06224 Winged helix DNA-binding domain 39 380 2.8E-73 T 29-03-2018 IPR009351 Protein of unknown function DUF1006 MSG_RS08780 a6e10403d5499267bbb69e1112980e4c 406 Gene3D G3DSA:1.10.10.10 206 283 0.015 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19040 333e861f92a2337149850cfcf3a8cccd 220 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 217 1.7E-62 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS19205 4c3ff19f515101acc6bceafb0166ae43 217 Pfam PF13489 Methyltransferase domain 27 190 1.1E-16 T 29-03-2018 MSG_RS19205 4c3ff19f515101acc6bceafb0166ae43 217 SUPERFAMILY SSF53335 29 200 3.92E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19205 4c3ff19f515101acc6bceafb0166ae43 217 Gene3D G3DSA:3.40.50.150 11 208 8.1E-21 T 29-03-2018 MSG_RS04035 d7db187baa811813eb55d80a00795589 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 1.9E-10 T 29-03-2018 MSG_RS04035 d7db187baa811813eb55d80a00795589 66 Gene3D G3DSA:3.30.70.20 1 62 7.2E-7 T 29-03-2018 MSG_RS04035 d7db187baa811813eb55d80a00795589 66 SUPERFAMILY SSF54862 1 60 1.63E-10 T 29-03-2018 MSG_RS08030 484d863589ca1e78168b2750c5fe1c9a 258 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 26 257 1.3E-54 T 29-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 MSG_RS08030 484d863589ca1e78168b2750c5fe1c9a 258 PIRSF PIRSF006648 1 258 2.1E-53 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS08030 484d863589ca1e78168b2750c5fe1c9a 258 Pfam PF12698 ABC-2 family transporter protein 49 247 1.8E-10 T 29-03-2018 MSG_RS10200 6d8de7c9f1d6140a80e3af6954840dde 143 SUPERFAMILY SSF49384 38 141 3.14E-31 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 MSG_RS10200 6d8de7c9f1d6140a80e3af6954840dde 143 Pfam PF00553 Cellulose binding domain 42 140 1.1E-30 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 MSG_RS10200 6d8de7c9f1d6140a80e3af6954840dde 143 SMART SM00637 41 141 1.2E-33 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 MSG_RS10200 6d8de7c9f1d6140a80e3af6954840dde 143 Gene3D G3DSA:2.60.40.290 32 141 8.0E-31 T 29-03-2018 MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 Gene3D G3DSA:1.20.1640.10 128 361 3.1E-26 T 29-03-2018 MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 SUPERFAMILY SSF82866 133 350 2.09E-29 T 29-03-2018 MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 PRINTS PR01755 Bacterial translocase SecF protein signature 76 91 7.7E-23 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 PRINTS PR01755 Bacterial translocase SecF protein signature 283 298 7.7E-23 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 PRINTS PR01755 Bacterial translocase SecF protein signature 200 214 7.7E-23 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 PRINTS PR01755 Bacterial translocase SecF protein signature 248 266 7.7E-23 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 49 351 23.331 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 Pfam PF07549 SecD/SecF GG Motif 72 92 2.2E-5 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 123 337 1.7E-50 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 Pfam PF02355 Protein export membrane protein 161 349 9.4E-64 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MSG_RS09705 44f447aa7e4d6d17f65e9fa79a8fdffc 439 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 77 340 3.7E-76 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PIRSF PIRSF001100 1 330 7.1E-95 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 66 85 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 249 262 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 267 287 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 134 149 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 189 202 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 219 229 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 106 119 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 PRINTS PR00733 Glycosyl hydrolase family 6 signature 291 305 2.0E-38 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 ProSitePatterns PS00656 Glycosyl hydrolases family 6 signature 2. 151 160 - T 29-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 Pfam PF01341 Glycosyl hydrolases family 6 68 314 7.1E-68 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 Gene3D G3DSA:3.20.20.40 47 329 4.3E-92 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS00460 5ef9300395b48e25227cf36e8e02632d 330 SUPERFAMILY SSF51989 38 329 4.58E-96 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 MSG_RS02845 ddae63fe03747ef6fdbe9075379cd081 140 Pfam PF11349 Protein of unknown function (DUF3151) 9 136 4.5E-58 T 29-03-2018 IPR014487 Protein of unknown function DUF3151 MSG_RS02845 ddae63fe03747ef6fdbe9075379cd081 140 Gene3D G3DSA:1.25.40.10 30 139 2.9E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS02845 ddae63fe03747ef6fdbe9075379cd081 140 PIRSF PIRSF017349 1 140 5.0E-66 T 29-03-2018 IPR014487 Protein of unknown function DUF3151 MSG_RS00360 187c95036dd128a43aa40f1a587e402f 274 Gene3D G3DSA:3.60.130.10 1 271 4.4E-35 T 29-03-2018 MSG_RS00360 187c95036dd128a43aa40f1a587e402f 274 SUPERFAMILY SSF51197 3 268 8.24E-47 T 29-03-2018 MSG_RS00360 187c95036dd128a43aa40f1a587e402f 274 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 4 254 1.9E-25 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MSG_RS20740 8e86791754c80e9b1b70c25c6ed3d1f5 274 Gene3D G3DSA:3.30.1330.30 9 108 3.9E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS20740 8e86791754c80e9b1b70c25c6ed3d1f5 274 SUPERFAMILY SSF55315 10 108 9.89E-12 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS20740 8e86791754c80e9b1b70c25c6ed3d1f5 274 SUPERFAMILY SSF75217 103 271 1.83E-36 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS20740 8e86791754c80e9b1b70c25c6ed3d1f5 274 Gene3D G3DSA:3.40.1280.10 109 272 2.3E-40 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS20740 8e86791754c80e9b1b70c25c6ed3d1f5 274 Pfam PF00588 SpoU rRNA Methylase family 125 267 7.8E-29 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 SUPERFAMILY SSF51735 5 252 2.13E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 1.5E-56 T 29-03-2018 MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 Gene3D G3DSA:3.40.50.720 43 253 6.1E-55 T 29-03-2018 MSG_RS06110 9b43c1e832a5578243c4cc60133cd0b4 253 Gene3D G3DSA:3.40.50.720 2 42 6.5E-6 T 29-03-2018 MSG_RS20685 b589f2a92edd99b2b10f1725ae583d30 521 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 57 5.2E-8 T 29-03-2018 MSG_RS20685 b589f2a92edd99b2b10f1725ae583d30 521 Gene3D G3DSA:3.50.50.60 7 520 2.3E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20685 b589f2a92edd99b2b10f1725ae583d30 521 SUPERFAMILY SSF51905 7 314 4.64E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Hamap MF_00259 Aminomethyltransferase [gcvT]. 6 364 42.08 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Gene3D G3DSA:4.10.1250.10 238 280 5.1E-13 T 29-03-2018 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Gene3D G3DSA:2.40.30.110 282 367 1.7E-22 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 SUPERFAMILY SSF101790 274 363 1.03E-24 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 358 2.2E-22 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 260 1.9E-82 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MSG_RS15390 6643734666681041dd32147627f5c5b8 367 PIRSF PIRSF006487 2 367 1.1E-84 T 29-03-2018 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 SUPERFAMILY SSF103025 7 281 1.33E-87 T 29-03-2018 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 8 362 1.2E-93 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Gene3D G3DSA:3.30.1360.120 7 137 2.6E-31 T 29-03-2018 MSG_RS15390 6643734666681041dd32147627f5c5b8 367 Gene3D G3DSA:3.30.1360.120 138 237 5.4E-22 T 29-03-2018 MSG_RS12525 edb7082840f73ecd0b3f5928a52707bb 277 Gene3D G3DSA:3.90.226.10 1 274 1.2E-49 T 29-03-2018 MSG_RS12525 edb7082840f73ecd0b3f5928a52707bb 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 236 4.8E-30 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS12525 edb7082840f73ecd0b3f5928a52707bb 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 112 132 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS12525 edb7082840f73ecd0b3f5928a52707bb 277 SUPERFAMILY SSF52096 4 256 2.64E-54 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS12145 e9cae248e7c6efda0cb2e348c58ab5b9 414 Gene3D G3DSA:2.60.120.600 96 195 9.4E-6 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS12145 e9cae248e7c6efda0cb2e348c58ab5b9 414 Gene3D G3DSA:2.60.120.600 229 375 1.0E-7 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 SUPERFAMILY SSF49503 147 170 6.53E-36 T 29-03-2018 IPR008972 Cupredoxin MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 SUPERFAMILY SSF49503 229 351 6.53E-36 T 29-03-2018 IPR008972 Cupredoxin MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 SUPERFAMILY SSF81464 39 142 4.74E-20 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 Gene3D G3DSA:1.10.287.90 54 142 1.3E-18 T 29-03-2018 MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 235 312 3.2E-13 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 252 306 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS15335 c07a7c0d6504d4781476b1e40a3fef73 362 Gene3D G3DSA:2.60.40.420 148 326 2.5E-44 T 29-03-2018 IPR008972 Cupredoxin MSG_RS22925 33bcb4825e22addc69c79b02fdf16917 162 SUPERFAMILY SSF50324 3 159 1.44E-60 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MSG_RS22925 33bcb4825e22addc69c79b02fdf16917 162 Pfam PF00719 Inorganic pyrophosphatase 5 158 3.0E-55 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MSG_RS22925 33bcb4825e22addc69c79b02fdf16917 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 35.604 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MSG_RS22925 33bcb4825e22addc69c79b02fdf16917 162 Gene3D G3DSA:3.90.80.10 1 161 9.8E-54 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MSG_RS22925 33bcb4825e22addc69c79b02fdf16917 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 Gene3D G3DSA:2.40.30.60 2 93 1.4E-24 T 29-03-2018 IPR002676 RimM protein GO:0006364 MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 171 7.0E-42 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 171 21.945 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 Gene3D G3DSA:2.30.30.240 100 171 1.8E-19 T 29-03-2018 MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 Pfam PF05239 PRC-barrel domain 98 172 7.4E-11 T 29-03-2018 IPR027275 PRC-barrel domain MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 SUPERFAMILY SSF50447 3 93 7.42E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 SUPERFAMILY SSF50346 100 171 1.55E-15 T 29-03-2018 IPR011033 PRC-barrel-like MSG_RS08205 c3fd988adaacaf55557f5ee1526bc31b 175 Pfam PF01782 RimM N-terminal domain 5 88 7.8E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 MSG_RS13705 5cd2b233aa8dabfb7160ecdd22c00d5a 487 Gene3D G3DSA:3.30.470.20 129 403 4.9E-20 T 29-03-2018 MSG_RS13705 5cd2b233aa8dabfb7160ecdd22c00d5a 487 SUPERFAMILY SSF56059 121 345 6.72E-21 T 29-03-2018 MSG_RS15700 b60f7d85efee6a92bc8cd77899a0f4c5 153 Pfam PF00578 AhpC/TSA family 4 129 2.5E-34 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS15700 b60f7d85efee6a92bc8cd77899a0f4c5 153 PIRSF PIRSF000239 1 153 7.0E-23 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS15700 b60f7d85efee6a92bc8cd77899a0f4c5 153 Gene3D G3DSA:3.40.30.10 1 153 4.2E-34 T 29-03-2018 MSG_RS15700 b60f7d85efee6a92bc8cd77899a0f4c5 153 SUPERFAMILY SSF52833 1 151 3.8E-39 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 19 223 33.683 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 131 3.3E-19 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 197 210 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 187 223 1.3E-11 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 PIRSF PIRSF000190 7 223 2.2E-64 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 8 212 1.6E-60 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 SUPERFAMILY SSF50475 26 223 1.14E-58 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS20700 8db7511ef3cb7e7aea9d47df7b46bdfb 223 Gene3D G3DSA:2.30.110.10 26 223 1.2E-58 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS14200 0ae0af87f737d6bbc1ed3712eb7f1aa4 223 SUPERFAMILY SSF51735 19 193 4.07E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14200 0ae0af87f737d6bbc1ed3712eb7f1aa4 223 Gene3D G3DSA:3.40.50.720 41 206 1.8E-31 T 29-03-2018 MSG_RS14200 0ae0af87f737d6bbc1ed3712eb7f1aa4 223 Pfam PF00107 Zinc-binding dehydrogenase 56 184 1.3E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS14200 0ae0af87f737d6bbc1ed3712eb7f1aa4 223 Gene3D G3DSA:3.90.180.10 1 40 1.2E-8 T 29-03-2018 MSG_RS14200 0ae0af87f737d6bbc1ed3712eb7f1aa4 223 SMART SM00829 1 220 1.8E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 5.1E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 5.1E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 5.1E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 5.1E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 Gene3D G3DSA:1.10.10.10 5 140 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 Pfam PF12802 MarR family 34 91 1.7E-14 T 29-03-2018 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 SMART SM00347 28 127 7.6E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS23915 c6823aa0ed338cfdfc3c478d10c7afc2 140 SUPERFAMILY SSF46785 13 139 1.19E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21795 01b4d80c2028b4f3f0b5782a5417752d 159 SUPERFAMILY SSF46785 11 148 1.48E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21795 01b4d80c2028b4f3f0b5782a5417752d 159 Pfam PF01638 HxlR-like helix-turn-helix 21 108 4.5E-20 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS21795 01b4d80c2028b4f3f0b5782a5417752d 159 Gene3D G3DSA:1.10.10.10 4 159 1.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08975 3f49a24d0fd32c14be15217ae10dec33 324 PIRSF PIRSF028754 20 323 7.4E-132 T 29-03-2018 IPR008492 Protein of unknown function DUF774 MSG_RS08975 3f49a24d0fd32c14be15217ae10dec33 324 Pfam PF09754 PAC2 family 43 259 8.3E-45 T 29-03-2018 IPR019151 Proteasome assembly chaperone 2 MSG_RS08975 3f49a24d0fd32c14be15217ae10dec33 324 Gene3D G3DSA:1.10.287.100 241 281 4.6E-17 T 29-03-2018 MSG_RS08975 3f49a24d0fd32c14be15217ae10dec33 324 SUPERFAMILY SSF159659 19 284 9.15E-89 T 29-03-2018 MSG_RS06700 2f2346ff70efa4b3ae981248b6588442 525 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 139 513 1.4E-115 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MSG_RS06700 2f2346ff70efa4b3ae981248b6588442 525 Pfam PF00361 Proton-conducting membrane transporter 166 461 2.6E-68 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06700 2f2346ff70efa4b3ae981248b6588442 525 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 8 514 17.573 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 SUPERFAMILY SSF56645 3 238 4.58E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 3.1E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Gene3D G3DSA:2.40.110.10 122 217 1.1E-36 T 29-03-2018 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Gene3D G3DSA:1.10.540.10 3 121 2.2E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 1.2E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 SUPERFAMILY SSF47203 228 378 3.06E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.2E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS20255 c1934727bf2eba63981c25b57c0ec8b8 382 Gene3D G3DSA:1.20.140.10 218 380 7.3E-44 T 29-03-2018 MSG_RS21895 7dea1ac648afe2a96a66a04142b6e3ce 136 Gene3D G3DSA:2.30.110.10 5 120 4.5E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS21895 7dea1ac648afe2a96a66a04142b6e3ce 136 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 26 128 1.7E-20 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS21895 7dea1ac648afe2a96a66a04142b6e3ce 136 SUPERFAMILY SSF50475 39 113 3.1E-6 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS21895 7dea1ac648afe2a96a66a04142b6e3ce 136 Pfam PF04075 F420H(2)-dependent quinone reductase 13 132 1.7E-26 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 Pfam PF13183 4Fe-4S dicluster domain 140 216 1.3E-14 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 Gene3D G3DSA:3.10.20.30 2 102 4.2E-29 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 SUPERFAMILY SSF54292 3 103 1.14E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 13 219 4.5E-45 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 SUPERFAMILY SSF46548 124 228 2.27E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 6 105 1.8E-28 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 Gene3D G3DSA:1.10.1060.10 103 238 8.9E-12 T 29-03-2018 MSG_RS02195 22cf58e47dabd32bab34f34b06cef936 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Gene3D G3DSA:3.30.300.30 444 543 1.7E-18 T 29-03-2018 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Gene3D G3DSA:3.40.50.980 29 186 9.3E-33 T 29-03-2018 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Pfam PF00501 AMP-binding enzyme 39 448 2.5E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 SUPERFAMILY SSF56801 22 541 9.16E-129 T 29-03-2018 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Gene3D G3DSA:2.30.38.10 366 443 2.4E-20 T 29-03-2018 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Gene3D G3DSA:3.40.50.980 187 354 5.3E-33 T 29-03-2018 MSG_RS16800 e3240e343dee06f159a7d18603d7af8e 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 533 4.7E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS08095 2a4f9eefb69c1e1ce05ce2d90dbcf3fb 183 SUPERFAMILY SSF117916 89 158 3.92E-14 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS08095 2a4f9eefb69c1e1ce05ce2d90dbcf3fb 183 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 111 158 3.0E-6 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS08095 2a4f9eefb69c1e1ce05ce2d90dbcf3fb 183 Pfam PF01106 NifU-like domain 111 158 1.5E-14 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS08095 2a4f9eefb69c1e1ce05ce2d90dbcf3fb 183 Gene3D G3DSA:3.30.300.130 90 170 6.1E-15 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS03000 77edffdc5bd4129b14c814cdcd67acca 323 Gene3D G3DSA:3.40.190.10 185 272 5.7E-19 T 29-03-2018 MSG_RS03000 77edffdc5bd4129b14c814cdcd67acca 323 SUPERFAMILY SSF53850 74 307 2.35E-54 T 29-03-2018 MSG_RS03000 77edffdc5bd4129b14c814cdcd67acca 323 SMART SM00062 88 310 2.2E-70 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS03000 77edffdc5bd4129b14c814cdcd67acca 323 Gene3D G3DSA:3.40.190.10 78 184 7.8E-24 T 29-03-2018 MSG_RS03000 77edffdc5bd4129b14c814cdcd67acca 323 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 89 308 6.7E-51 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS22110 dd5269322c06ef3169b076c9a2854793 272 SMART SM00460 156 216 8.8E-13 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS22110 dd5269322c06ef3169b076c9a2854793 272 SUPERFAMILY SSF54001 100 241 3.36E-26 T 29-03-2018 MSG_RS22110 dd5269322c06ef3169b076c9a2854793 272 Pfam PF01841 Transglutaminase-like superfamily 125 213 2.7E-18 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS22110 dd5269322c06ef3169b076c9a2854793 272 Gene3D G3DSA:3.90.260.10 124 193 1.0E-4 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS03575 71d62a702914c6d72945507f0c83be0f 96 SUPERFAMILY SSF140453 5 96 1.28E-20 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS03575 71d62a702914c6d72945507f0c83be0f 96 Pfam PF06013 Proteins of 100 residues with WXG 5 86 1.1E-10 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS03575 71d62a702914c6d72945507f0c83be0f 96 Gene3D G3DSA:1.10.287.1060 3 96 2.2E-14 T 29-03-2018 MSG_RS20475 f5740df1e3b5289c75d181938852fb95 308 SUPERFAMILY SSF161098 35 287 1.59E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS20475 f5740df1e3b5289c75d181938852fb95 308 Gene3D G3DSA:1.10.3720.10 18 290 8.5E-37 T 29-03-2018 MSG_RS20475 f5740df1e3b5289c75d181938852fb95 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 296 4.7E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS20475 f5740df1e3b5289c75d181938852fb95 308 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 27 289 8.4E-74 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MSG_RS01260 ac6a6f306e594ffaa1681b045b452afb 342 Pfam PF00756 Putative esterase 61 322 1.9E-71 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS01260 ac6a6f306e594ffaa1681b045b452afb 342 SUPERFAMILY SSF53474 49 327 7.19E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01260 ac6a6f306e594ffaa1681b045b452afb 342 Gene3D G3DSA:3.40.50.1820 45 328 9.0E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS07910 83343e4c4cf42955cc8597cc7a9a6d9e 417 Gene3D G3DSA:1.10.287.1060 21 105 1.5E-7 T 29-03-2018 MSG_RS07910 83343e4c4cf42955cc8597cc7a9a6d9e 417 SUPERFAMILY SSF140459 3 174 6.02E-63 T 29-03-2018 MSG_RS07910 83343e4c4cf42955cc8597cc7a9a6d9e 417 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 320 383 6.1E-6 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS07910 83343e4c4cf42955cc8597cc7a9a6d9e 417 Pfam PF00823 PPE family 5 160 8.3E-62 T 29-03-2018 IPR000030 PPE family MSG_RS16315 e87bc399af49732ffc0cef53bf0776ca 422 SUPERFAMILY SSF55874 316 414 4.32E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16315 e87bc399af49732ffc0cef53bf0776ca 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 413 2.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16315 e87bc399af49732ffc0cef53bf0776ca 422 Gene3D G3DSA:3.30.565.10 187 414 7.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS16315 e87bc399af49732ffc0cef53bf0776ca 422 SMART SM00387 319 415 9.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05550 d0aa2f25cd0359737d864389cc8b0413 244 SUPERFAMILY SSF53271 3 205 1.84E-58 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS05550 d0aa2f25cd0359737d864389cc8b0413 244 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 206 1.7E-73 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MSG_RS05550 d0aa2f25cd0359737d864389cc8b0413 244 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 39.673 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MSG_RS05550 d0aa2f25cd0359737d864389cc8b0413 244 Pfam PF14681 Uracil phosphoribosyltransferase 5 205 6.3E-62 T 29-03-2018 MSG_RS05550 d0aa2f25cd0359737d864389cc8b0413 244 Gene3D G3DSA:3.40.50.2020 1 205 1.2E-58 T 29-03-2018 MSG_RS09810 464be1a092226cd8e0a469c8a7a78764 357 Pfam PF13515 Fusaric acid resistance protein-like 39 164 9.3E-13 T 29-03-2018 MSG_RS19985 c8c6aec9e2a482eb5da491df1749ef05 526 Gene3D G3DSA:3.40.50.720 190 319 2.6E-10 T 29-03-2018 MSG_RS19985 c8c6aec9e2a482eb5da491df1749ef05 526 Pfam PF02397 Bacterial sugar transferase 332 520 3.7E-65 T 29-03-2018 IPR003362 Bacterial sugar transferase MSG_RS19985 c8c6aec9e2a482eb5da491df1749ef05 526 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 65 526 4.7E-123 T 29-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 SUPERFAMILY SSF63380 93 198 2.04E-31 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 Gene3D G3DSA:2.40.30.20 1 93 7.2E-27 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 Pfam PF00677 Lumazine binding domain 100 187 6.0E-25 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 Pfam PF00677 Lumazine binding domain 3 87 9.8E-22 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 6.6E-59 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 SUPERFAMILY SSF63380 1 88 7.23E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 PIRSF PIRSF000498 1 200 2.6E-69 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MSG_RS10355 c8bda9ef58ee32e08836c1de6339e18a 200 Gene3D G3DSA:2.40.30.20 94 194 4.9E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 12 220 1.3E-84 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 Gene3D G3DSA:3.20.20.70 3 224 5.7E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 38 52 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 PIRSF PIRSF001461 7 230 7.2E-94 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 140 162 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 Pfam PF00834 Ribulose-phosphate 3 epimerase family 13 207 1.1E-80 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MSG_RS10335 b39c85f2a810672d1a01beaa907f77fa 232 SUPERFAMILY SSF51366 12 221 2.15E-66 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS20815 18a58c9ca9bfc63bb70c244d6924f7e6 174 Pfam PF01967 MoaC family 34 167 4.3E-52 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MSG_RS20815 18a58c9ca9bfc63bb70c244d6924f7e6 174 SUPERFAMILY SSF55040 30 172 5.89E-56 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MSG_RS20815 18a58c9ca9bfc63bb70c244d6924f7e6 174 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 23 168 1.4E-63 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MSG_RS20815 18a58c9ca9bfc63bb70c244d6924f7e6 174 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 21 174 33.888 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MSG_RS20815 18a58c9ca9bfc63bb70c244d6924f7e6 174 Gene3D G3DSA:3.30.70.640 21 174 3.4E-63 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MSG_RS19045 486d4996bda8772d7b2c5e3b102785f3 358 Gene3D G3DSA:3.40.50.1820 28 314 2.4E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19045 486d4996bda8772d7b2c5e3b102785f3 358 Pfam PF08237 PE-PPE domain 76 310 9.8E-71 T 29-03-2018 IPR013228 PE-PPE, C-terminal MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 Gene3D G3DSA:3.40.50.720 2 249 2.2E-60 T 29-03-2018 MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 246 1.4E-43 T 29-03-2018 MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 SUPERFAMILY SSF51735 6 248 6.41E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 4.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06115 132f03ce761df5df16687ca09c76dc8f 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.2E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17150 651f545795a9585e6f12d7e1b1da5f10 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 103 19.804 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17150 651f545795a9585e6f12d7e1b1da5f10 103 SUPERFAMILY SSF141091 4 102 1.01E-31 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17150 651f545795a9585e6f12d7e1b1da5f10 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 1.8E-25 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS17150 651f545795a9585e6f12d7e1b1da5f10 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS17150 651f545795a9585e6f12d7e1b1da5f10 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 4.7E-34 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01910 8a26f00db45c94d18f27f8ddc39b45e2 164 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 117 2.0E-25 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS01910 8a26f00db45c94d18f27f8ddc39b45e2 164 Pfam PF16525 Haemophore, haem-binding 39 116 1.7E-26 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS01910 8a26f00db45c94d18f27f8ddc39b45e2 164 TIGRFAM TIGR04530 hemophoreRv0203: hemophore 16 133 5.8E-54 T 29-03-2018 IPR030937 Hemophore Rv0203 GO:0015886|GO:0020037 MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 SUPERFAMILY SSF51735 12 266 5.04E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 Pfam PF00106 short chain dehydrogenase 12 197 3.0E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 193 0.0068 T 29-03-2018 MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 Gene3D G3DSA:3.40.50.720 10 286 4.5E-60 T 29-03-2018 MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07380 40e8ddf9027541f0b7132e1d1559ed19 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.4E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 SUPERFAMILY SSF82866 138 345 2.35E-26 T 29-03-2018 MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 Pfam PF03176 MMPL family 48 351 5.2E-42 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 Pfam PF03176 MMPL family 435 753 6.2E-30 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 SUPERFAMILY SSF82866 529 747 5.62E-31 T 29-03-2018 MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 Gene3D G3DSA:1.20.1640.10 513 744 4.7E-30 T 29-03-2018 MSG_RS01925 a8716444e63aa2f91e36a411e2249bcc 943 Gene3D G3DSA:1.20.1640.10 124 348 2.4E-28 T 29-03-2018 MSG_RS13165 b4c6fa751899774e3168a3197de80b0f 450 Gene3D G3DSA:3.10.20.70 13 107 9.1E-10 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS13165 b4c6fa751899774e3168a3197de80b0f 450 Pfam PF00120 Glutamine synthetase, catalytic domain 112 432 1.6E-64 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS13165 b4c6fa751899774e3168a3197de80b0f 450 Gene3D G3DSA:3.30.590.10 108 446 2.7E-83 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS13165 b4c6fa751899774e3168a3197de80b0f 450 SUPERFAMILY SSF55931 113 436 9.81E-78 T 29-03-2018 MSG_RS13165 b4c6fa751899774e3168a3197de80b0f 450 SMART SM01230 111 358 4.6E-72 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS10535 6753b110f4195f4ed40b07ca7b775513 321 Pfam PF02628 Cytochrome oxidase assembly protein 27 203 3.2E-12 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MSG_RS03545 70836bbbffe42c727f32666e17a839e4 309 Pfam PF02353 Mycolic acid cyclopropane synthetase 13 305 2.6E-103 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03545 70836bbbffe42c727f32666e17a839e4 309 Gene3D G3DSA:3.40.50.150 12 309 1.8E-49 T 29-03-2018 MSG_RS03545 70836bbbffe42c727f32666e17a839e4 309 PIRSF PIRSF003085 3 309 9.5E-90 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS03545 70836bbbffe42c727f32666e17a839e4 309 SUPERFAMILY SSF53335 21 309 5.98E-67 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS00750 25d7f9baef3ae5578e848f43ec2d369b 521 Pfam PF00916 Sulfate permease family 27 384 3.1E-72 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MSG_RS08020 e0cfe107e97f6cdd0280636c8c129b85 418 SUPERFAMILY SSF52777 200 410 8.0E-47 T 29-03-2018 MSG_RS08020 e0cfe107e97f6cdd0280636c8c129b85 418 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 296 391 2.1E-25 T 29-03-2018 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal MSG_RS08020 e0cfe107e97f6cdd0280636c8c129b85 418 SUPERFAMILY SSF52777 17 154 6.12E-16 T 29-03-2018 MSG_RS08020 e0cfe107e97f6cdd0280636c8c129b85 418 Gene3D G3DSA:3.30.559.10 10 193 3.6E-11 T 29-03-2018 MSG_RS24535 5b7552abf91433f1709064f74363a379 501 Gene3D G3DSA:1.10.287.1060 141 232 0.012 T 29-03-2018 MSG_RS24535 5b7552abf91433f1709064f74363a379 501 Gene3D G3DSA:1.10.287.1060 5 93 0.0066 T 29-03-2018 MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 Gene3D G3DSA:2.120.10.30 2 121 2.2E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 Gene3D G3DSA:2.120.10.30 124 270 6.5E-17 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 256 7.5E-44 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 2.6E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 2.6E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 136 158 2.6E-6 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) MSG_RS02430 bb20701a2390870bd2344c39514fb760 292 SUPERFAMILY SSF63829 3 283 1.85E-48 T 29-03-2018 MSG_RS15955 3a8c78d4c2bcf499411b04378a9854bd 272 Pfam PF01553 Acyltransferase 37 165 4.3E-10 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS15955 3a8c78d4c2bcf499411b04378a9854bd 272 PIRSF PIRSF016753 3 272 1.2E-72 T 29-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted MSG_RS15955 3a8c78d4c2bcf499411b04378a9854bd 272 SMART SM00563 50 169 4.2E-4 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS15955 3a8c78d4c2bcf499411b04378a9854bd 272 Gene3D G3DSA:3.40.1130.10 4 267 4.1E-9 T 29-03-2018 MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 92 229 2.6E-10 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 SUPERFAMILY SSF52540 5 310 1.11E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 Hamap MF_00215 Pantothenate kinase [coaA]. 1 312 173.801 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 Gene3D G3DSA:3.40.50.300 7 311 6.2E-51 T 29-03-2018 MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 311 8.2E-119 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS19580 66d1a0bd659de52e4c525edbaba2963f 312 PIRSF PIRSF000545 2 312 1.7E-139 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MSG_RS03755 adcca8c49fcf01a5bbb11700ae829e89 148 SUPERFAMILY SSF53448 5 141 3.24E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS03755 adcca8c49fcf01a5bbb11700ae829e89 148 Pfam PF00535 Glycosyl transferase family 2 7 119 2.2E-20 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS03755 adcca8c49fcf01a5bbb11700ae829e89 148 Gene3D G3DSA:3.90.550.10 2 143 2.9E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 Pfam PF01494 FAD binding domain 3 333 8.6E-10 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 Gene3D G3DSA:3.50.50.60 1 366 4.2E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 3.6E-11 T 29-03-2018 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.6E-11 T 29-03-2018 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.6E-11 T 29-03-2018 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.6E-11 T 29-03-2018 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 SUPERFAMILY SSF51905 1 165 2.59E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS20920 83775b9702aff881a7bb986f225e77aa 402 SUPERFAMILY SSF51905 265 370 2.59E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 Gene3D G3DSA:3.30.300.30 462 598 2.2E-17 T 29-03-2018 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 Pfam PF00501 AMP-binding enzyme 30 467 2.1E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 Gene3D G3DSA:2.30.38.10 386 460 1.7E-20 T 29-03-2018 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 Gene3D G3DSA:3.40.50.980 13 191 6.3E-37 T 29-03-2018 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 SUPERFAMILY SSF56801 338 597 7.85E-115 T 29-03-2018 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 SUPERFAMILY SSF56801 26 290 7.85E-115 T 29-03-2018 MSG_RS15260 fb9d61d6a377f27fa68cbbc8144b0626 599 Gene3D G3DSA:3.40.50.980 192 385 5.7E-39 T 29-03-2018 MSG_RS02645 d0a1b8ac82aee0159071a2cd924c3348 288 Gene3D G3DSA:3.90.550.10 1 288 1.5E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS02645 d0a1b8ac82aee0159071a2cd924c3348 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 5.0E-147 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MSG_RS02645 d0a1b8ac82aee0159071a2cd924c3348 288 SUPERFAMILY SSF53448 1 286 4.55E-85 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS02645 d0a1b8ac82aee0159071a2cd924c3348 288 Pfam PF00483 Nucleotidyl transferase 3 236 1.2E-64 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MSG_RS08865 527ba73d25f5d600936cd6d6c6083365 143 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 11 129 1.0E-51 T 29-03-2018 IPR013100 Limonene-1,2-epoxide hydrolase MSG_RS08865 527ba73d25f5d600936cd6d6c6083365 143 Gene3D G3DSA:3.10.450.50 5 142 2.6E-21 T 29-03-2018 MSG_RS08865 527ba73d25f5d600936cd6d6c6083365 143 SUPERFAMILY SSF54427 11 135 3.6E-36 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 Gene3D G3DSA:3.90.650.10 181 358 1.1E-55 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 SUPERFAMILY SSF55326 17 179 7.18E-45 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 17 357 40.402 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 Gene3D G3DSA:3.30.1330.10 47 171 4.3E-45 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 17 347 5.3E-140 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 SUPERFAMILY SSF56042 182 351 2.54E-53 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 352 1.8E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MSG_RS21765 2e72b6d1b3aa781055c836ad474c9ee7 364 Pfam PF00586 AIR synthase related protein, N-terminal domain 70 174 4.0E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MSG_RS04535 1b5df2ebee14e92bfd8056d11aecd4b2 330 Pfam PF14494 Domain of unknown function (DUF4436) 70 328 9.5E-94 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS08540 06d2185009c8465cd640790e26615698 160 SUPERFAMILY SSF89919 2 116 1.05E-24 T 29-03-2018 IPR023799 Ribosome-binding factor A domain MSG_RS08540 06d2185009c8465cd640790e26615698 160 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 3.9E-16 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MSG_RS08540 06d2185009c8465cd640790e26615698 160 Gene3D G3DSA:3.30.300.20 5 120 6.4E-24 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS08540 06d2185009c8465cd640790e26615698 160 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 89 1.0E-32 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MSG_RS08540 06d2185009c8465cd640790e26615698 160 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 MSG_RS08540 06d2185009c8465cd640790e26615698 160 Pfam PF02033 Ribosome-binding factor A 6 113 3.8E-22 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MSG_RS08540 06d2185009c8465cd640790e26615698 160 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 17.692 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MSG_RS23180 efe6d684f42342a3771eb90c13a3fb1c 346 Gene3D G3DSA:3.40.50.1100 21 133 1.0E-23 T 29-03-2018 MSG_RS23180 efe6d684f42342a3771eb90c13a3fb1c 346 Gene3D G3DSA:3.40.50.1100 134 322 1.9E-42 T 29-03-2018 MSG_RS23180 efe6d684f42342a3771eb90c13a3fb1c 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 305 3.4E-47 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS23180 efe6d684f42342a3771eb90c13a3fb1c 346 SUPERFAMILY SSF53686 11 326 1.96E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.4E-8 T 29-03-2018 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 205 230 5.4E-8 T 29-03-2018 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 Gene3D G3DSA:3.50.50.60 1 389 3.1E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 Gene3D G3DSA:3.50.50.60 397 558 1.3E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 SUPERFAMILY SSF56425 316 495 4.45E-34 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 Pfam PF00890 FAD binding domain 7 541 6.7E-90 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 SUPERFAMILY SSF51905 212 321 2.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 SUPERFAMILY SSF51905 156 174 2.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 SUPERFAMILY SSF51905 4 119 2.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22460 ffd0589e2a993493662e61b9dcaa037c 560 SUPERFAMILY SSF51905 500 558 2.17E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 SUPERFAMILY SSF52540 9 278 2.07E-117 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 Pfam PF00117 Glutamine amidotransferase class-I 313 542 1.6E-44 T 29-03-2018 IPR017926 Glutamine amidotransferase MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 SUPERFAMILY SSF52317 301 549 1.01E-69 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 Pfam PF06418 CTP synthase N-terminus 10 278 4.1E-121 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 Gene3D G3DSA:3.40.50.880 298 552 3.7E-65 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 TIGRFAM TIGR00337 PyrG: CTP synthase 9 544 1.9E-223 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 Gene3D G3DSA:3.40.50.300 1 297 3.8E-128 T 29-03-2018 MSG_RS11720 a1d5ef38af5b66c4d4fd1f240350ae8e 583 Hamap MF_01227 CTP synthase [pyrG]. 9 549 48.986 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 SUPERFAMILY SSF52540 469 682 8.9E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 SUPERFAMILY SSF52540 1125 1224 5.06E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Gene3D G3DSA:3.40.50.300 771 1049 0.0023 T 29-03-2018 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Gene3D G3DSA:3.40.50.300 1076 1289 3.4E-6 T 29-03-2018 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Gene3D G3DSA:3.40.50.300 433 693 6.1E-12 T 29-03-2018 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 SUPERFAMILY SSF52540 829 1035 1.21E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 777 1355 6.2E-152 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Pfam PF01580 FtsK/SpoIIIE family 493 593 1.7E-10 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Pfam PF01580 FtsK/SpoIIIE family 811 1067 2.6E-51 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 Pfam PF01580 FtsK/SpoIIIE family 1137 1222 1.2E-6 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS00230 3671d57531dd7147f9a9524258cb6282 1359 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 25 716 2.2E-199 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS01135 9a966f089d932dfe3d7fb5bcb2d1e3cc 618 SUPERFAMILY SSF51905 73 302 3.15E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01135 9a966f089d932dfe3d7fb5bcb2d1e3cc 618 SUPERFAMILY SSF51905 407 532 3.15E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01135 9a966f089d932dfe3d7fb5bcb2d1e3cc 618 Pfam PF13450 NAD(P)-binding Rossmann-like domain 75 125 2.7E-7 T 29-03-2018 MSG_RS01135 9a966f089d932dfe3d7fb5bcb2d1e3cc 618 Gene3D G3DSA:3.50.50.60 59 241 3.7E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01135 9a966f089d932dfe3d7fb5bcb2d1e3cc 618 Gene3D G3DSA:3.50.50.60 244 618 3.3E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06900 eec0b728c2c026a46ca5f1346757dc6b 281 SUPERFAMILY SSF109854 8 163 5.19E-31 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS06900 eec0b728c2c026a46ca5f1346757dc6b 281 Gene3D G3DSA:1.20.120.450 6 163 5.0E-28 T 29-03-2018 MSG_RS06900 eec0b728c2c026a46ca5f1346757dc6b 281 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 20 158 1.8E-31 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MSG_RS06900 eec0b728c2c026a46ca5f1346757dc6b 281 Pfam PF07398 MDMPI C-terminal domain 177 272 1.1E-13 T 29-03-2018 IPR010872 MDMPI C-terminal MSG_RS06900 eec0b728c2c026a46ca5f1346757dc6b 281 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 19 251 3.0E-41 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS06210 65d19443ce4b1ff7fae77a401c7b4e57 203 SUPERFAMILY SSF53254 6 197 8.77E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS06210 65d19443ce4b1ff7fae77a401c7b4e57 203 Gene3D G3DSA:3.40.50.1240 2 199 3.4E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS06210 65d19443ce4b1ff7fae77a401c7b4e57 203 PIRSF PIRSF000709 2 166 2.3E-7 T 29-03-2018 MSG_RS06210 65d19443ce4b1ff7fae77a401c7b4e57 203 SMART SM00855 7 154 7.7E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS06210 65d19443ce4b1ff7fae77a401c7b4e57 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 192 8.9E-42 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS12085 82387a06066813e598be04b450e7d5d1 165 SMART SM00903 13 164 3.7E-18 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS12085 82387a06066813e598be04b450e7d5d1 165 SUPERFAMILY SSF50475 6 150 1.77E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS12085 82387a06066813e598be04b450e7d5d1 165 Gene3D G3DSA:2.30.110.10 4 161 3.9E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS12085 82387a06066813e598be04b450e7d5d1 165 Pfam PF01613 Flavin reductase like domain 18 132 1.2E-15 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 Gene3D G3DSA:1.10.10.10 21 127 3.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 3.2E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 74 3.2E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 3.2E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 91 106 3.2E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 SUPERFAMILY SSF46785 31 115 6.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 Pfam PF01022 Bacterial regulatory protein, arsR family 50 94 5.0E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS16660 ee27d63d14bd0282c74aaf66fd6035c2 127 SMART SM00418 42 120 1.2E-28 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS04980 7773296c628284915313536aa5915f67 464 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 38 384 7.4E-73 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MSG_RS04980 7773296c628284915313536aa5915f67 464 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 15 448 2.2E-205 T 29-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 MSG_RS04980 7773296c628284915313536aa5915f67 464 Gene3D G3DSA:3.90.1150.10 328 450 4.0E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS04980 7773296c628284915313536aa5915f67 464 SUPERFAMILY SSF53383 11 447 6.42E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS04980 7773296c628284915313536aa5915f67 464 Gene3D G3DSA:3.40.640.10 64 327 1.8E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 SUPERFAMILY SSF56235 10 527 1.78E-176 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS21980 441ea50580c52cc43778a2a504341240 527 Pfam PF01019 Gamma-glutamyltranspeptidase 37 522 1.1E-160 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 348 366 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 403 418 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 427 444 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 255 274 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS21980 441ea50580c52cc43778a2a504341240 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 372 390 5.7E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 40.398 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 Gene3D G3DSA:3.65.10.10 22 220 7.2E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 7.6E-116 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 4.6E-170 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 SUPERFAMILY SSF55205 4 416 1.96E-131 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MSG_RS18225 193f3fcc748bcd5baf0106c1a17c0318 417 Gene3D G3DSA:3.65.10.10 221 417 5.6E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MSG_RS21460 7d216f869e995747837346d8869a024e 315 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 9 307 1.6E-55 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MSG_RS21460 7d216f869e995747837346d8869a024e 315 Gene3D G3DSA:3.40.830.10 1 308 7.4E-49 T 29-03-2018 MSG_RS21460 7d216f869e995747837346d8869a024e 315 SUPERFAMILY SSF53213 232 310 3.4E-67 T 29-03-2018 MSG_RS21460 7d216f869e995747837346d8869a024e 315 SUPERFAMILY SSF53213 6 188 3.4E-67 T 29-03-2018 MSG_RS21460 7d216f869e995747837346d8869a024e 315 Hamap MF_01653 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase [mhpB]. 4 315 52.452 T 29-03-2018 IPR023789 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase GO:0005506|GO:0019439|GO:0047070|GO:0055114 KEGG: 00360+1.13.11.16|MetaCyc: PWY-6690 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Gene3D G3DSA:3.30.950.10 171 306 7.0E-28 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Pfam PF02602 Uroporphyrinogen-III synthase HemD 306 536 3.7E-62 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 246 2.7E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Gene3D G3DSA:3.40.50.10090 453 547 1.0E-21 T 29-03-2018 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Gene3D G3DSA:3.40.50.10090 324 452 3.1E-30 T 29-03-2018 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 Gene3D G3DSA:3.40.1010.10 15 170 9.7E-30 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 SUPERFAMILY SSF53790 13 72 1.43E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 SUPERFAMILY SSF53790 103 295 1.43E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS03600 ba70c43031b836edd43d206980ff977b 562 SUPERFAMILY SSF69618 292 543 5.36E-69 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 SUPERFAMILY SSF56655 11 291 6.54E-64 T 29-03-2018 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 Pfam PF00459 Inositol monophosphatase family 13 290 4.0E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 240 254 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 107 120 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 Gene3D G3DSA:3.40.190.80 173 296 3.6E-33 T 29-03-2018 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 80 1.9E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 227 1.9E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.9E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 PRINTS PR00377 Inositol monophosphatase superfamily signature 237 261 1.9E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 PRINTS PR00377 Inositol monophosphatase superfamily signature 107 123 1.9E-29 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS09045 83bdf51624c5dba03f342538580c7cf7 300 Gene3D G3DSA:3.30.540.10 7 172 2.8E-38 T 29-03-2018 MSG_RS10590 74309540c24f97f096d7d76e1daba728 162 Pfam PF01592 NifU-like N terminal domain 6 129 4.0E-33 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MSG_RS10590 74309540c24f97f096d7d76e1daba728 162 SUPERFAMILY SSF82649 2 142 1.07E-42 T 29-03-2018 MSG_RS10590 74309540c24f97f096d7d76e1daba728 162 Gene3D G3DSA:3.90.1010.10 3 159 1.3E-46 T 29-03-2018 MSG_RS10590 74309540c24f97f096d7d76e1daba728 162 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 141 1.3E-49 T 29-03-2018 MSG_RS06375 e73bb8fa81bf0b8874c0bdc25c1ee369 95 Pfam PF09723 Zinc ribbon domain 1 40 2.0E-9 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS06375 e73bb8fa81bf0b8874c0bdc25c1ee369 95 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 2.5E-12 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS06375 e73bb8fa81bf0b8874c0bdc25c1ee369 95 SMART SM00834 1 41 6.5E-9 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS03440 c5a2e0bcd67d7fe97207d164ebcf568c 463 Gene3D G3DSA:2.40.440.10 259 386 4.5E-21 T 29-03-2018 MSG_RS03440 c5a2e0bcd67d7fe97207d164ebcf568c 463 Pfam PF03734 L,D-transpeptidase catalytic domain 266 384 1.5E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS03440 c5a2e0bcd67d7fe97207d164ebcf568c 463 SUPERFAMILY SSF141523 263 384 9.16E-22 T 29-03-2018 MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 SUPERFAMILY SSF51735 3 244 5.51E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 Pfam PF00106 short chain dehydrogenase 4 189 3.5E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.7E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.7E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.7E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.7E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.7E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS03860 4e0f0ea325b8eafcd61a9eea2976d998 274 Gene3D G3DSA:3.40.50.720 1 273 1.4E-64 T 29-03-2018 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 28 294 9.7E-44 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 SUPERFAMILY SSF53335 23 292 6.08E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 43 290 3.2E-61 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 Pfam PF05175 Methyltransferase small domain 122 207 6.9E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 21 294 38.244 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 199 205 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 Gene3D G3DSA:1.10.8.10 6 92 1.5E-14 T 29-03-2018 MSG_RS18295 8d86d5a190b82f71e64641a610deb436 307 Gene3D G3DSA:3.40.50.150 93 297 1.0E-39 T 29-03-2018 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 PIRSF PIRSF016578 1 393 5.2E-135 T 29-03-2018 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 SUPERFAMILY SSF56645 5 208 1.3E-26 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 371 7.4E-43 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 Gene3D G3DSA:1.10.540.10 2 103 5.8E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 Gene3D G3DSA:2.40.110.10 108 210 6.9E-13 T 29-03-2018 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 Gene3D G3DSA:1.20.140.10 211 385 1.4E-20 T 29-03-2018 MSG_RS12205 4c96e96ec09155361782929ae49945f1 397 SUPERFAMILY SSF47203 230 367 2.42E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 Gene3D G3DSA:2.10.240.10 243 273 8.6E-7 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00406 Cytochrome B5 reductase signature 121 140 3.6E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00406 Cytochrome B5 reductase signature 211 219 3.6E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00406 Cytochrome B5 reductase signature 97 111 3.6E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00406 Cytochrome B5 reductase signature 159 170 3.6E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 Gene3D G3DSA:3.40.50.80 100 239 9.9E-23 T 29-03-2018 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 Pfam PF00175 Oxidoreductase NAD-binding domain 122 222 1.9E-13 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 Gene3D G3DSA:2.40.30.10 10 99 1.0E-11 T 29-03-2018 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 SUPERFAMILY SSF52343 116 258 8.64E-30 T 29-03-2018 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PIRSF PIRSF006816 13 275 4.0E-57 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 SUPERFAMILY SSF63380 14 109 5.38E-16 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 147 156 2.0E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 121 140 2.0E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 159 170 2.0E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 211 219 2.0E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MSG_RS14150 2dbc7337dd6086fb271efe1d3014c8f0 284 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 243 270 6.9E-6 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain MSG_RS20535 c6d00281f528098be45727eaad49fdfa 447 Pfam PF13827 Domain of unknown function (DUF4189) 254 339 9.6E-7 T 29-03-2018 IPR025240 Domain of unknown function DUF4189 MSG_RS20535 c6d00281f528098be45727eaad49fdfa 447 Pfam PF05305 Protein of unknown function (DUF732) 365 445 4.3E-13 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS21325 9bff756bacb2e40d6a35f0f0942dd969 149 Gene3D G3DSA:3.10.450.50 6 138 4.3E-17 T 29-03-2018 MSG_RS21325 9bff756bacb2e40d6a35f0f0942dd969 149 SUPERFAMILY SSF54427 12 146 2.48E-22 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS21325 9bff756bacb2e40d6a35f0f0942dd969 149 Pfam PF13577 SnoaL-like domain 14 125 4.8E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 SUPERFAMILY SSF51735 152 339 2.39E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 Gene3D G3DSA:3.40.50.720 173 322 3.1E-25 T 29-03-2018 MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 Pfam PF00107 Zinc-binding dehydrogenase 186 317 6.6E-11 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 Gene3D G3DSA:3.90.180.10 1 172 2.5E-46 T 29-03-2018 MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 4.2E-9 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 7.4E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS07410 aca220caa1ae3375fd4905631fa5f1db 380 SUPERFAMILY SSF50129 1 185 1.49E-59 T 29-03-2018 IPR011032 GroES-like MSG_RS05750 9847862edd440783d335f080755d301e 181 Gene3D G3DSA:3.40.50.2300 2 171 3.7E-30 T 29-03-2018 MSG_RS05750 9847862edd440783d335f080755d301e 181 SUPERFAMILY SSF52172 7 134 4.27E-32 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS05750 9847862edd440783d335f080755d301e 181 Pfam PF00072 Response regulator receiver domain 10 130 1.4E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05750 9847862edd440783d335f080755d301e 181 SMART SM00448 8 130 6.2E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS12650 429e876a091f5498888d5ac4404fbf2a 413 Pfam PF00823 PPE family 6 162 7.1E-64 T 29-03-2018 IPR000030 PPE family MSG_RS12650 429e876a091f5498888d5ac4404fbf2a 413 SUPERFAMILY SSF140459 3 171 6.54E-63 T 29-03-2018 MSG_RS12650 429e876a091f5498888d5ac4404fbf2a 413 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 327 409 2.2E-14 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12650 429e876a091f5498888d5ac4404fbf2a 413 Gene3D G3DSA:1.10.287.1060 23 105 1.2E-6 T 29-03-2018 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 29 197 1.2E-34 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 301 18.244 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 Pfam PF01171 PP-loop family 28 192 1.0E-30 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 SUPERFAMILY SSF52402 24 226 6.81E-42 T 29-03-2018 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 Gene3D G3DSA:3.40.50.620 20 222 5.7E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 Pfam PF09179 TilS substrate binding domain 242 296 7.7E-9 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MSG_RS22910 7ad31a1e72b7efe21e3d637042fe860c 319 SUPERFAMILY SSF82829 206 299 6.41E-14 T 29-03-2018 MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 0.0021 T 29-03-2018 MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 Gene3D G3DSA:3.40.50.720 6 249 3.6E-33 T 29-03-2018 MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 SUPERFAMILY SSF51735 9 247 8.96E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 Pfam PF00106 short chain dehydrogenase 9 192 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14645 be651e04aed2b94ff2e7ce845dad8f87 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS23840 5448c6bb2ac3ab437f06a55868f08eab 348 Gene3D G3DSA:3.30.200.20 9 110 4.6E-24 T 29-03-2018 MSG_RS23840 5448c6bb2ac3ab437f06a55868f08eab 348 Pfam PF01636 Phosphotransferase enzyme family 34 263 5.5E-42 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS23840 5448c6bb2ac3ab437f06a55868f08eab 348 SUPERFAMILY SSF56112 10 316 8.6E-47 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS23840 5448c6bb2ac3ab437f06a55868f08eab 348 Gene3D G3DSA:3.90.1200.10 126 302 3.6E-24 T 29-03-2018 MSG_RS20530 f92a4596549ac021604bd1cad286e7c0 120 Pfam PF05305 Protein of unknown function (DUF732) 21 104 1.1E-8 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS20650 ff8823da55bd7c4d2049b8fc7ff73b14 207 SUPERFAMILY SSF46689 8 74 7.7E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS20650 ff8823da55bd7c4d2049b8fc7ff73b14 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 6.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS20650 ff8823da55bd7c4d2049b8fc7ff73b14 207 Gene3D G3DSA:1.10.10.60 5 58 4.2E-11 T 29-03-2018 MSG_RS20650 ff8823da55bd7c4d2049b8fc7ff73b14 207 Gene3D G3DSA:1.10.357.10 59 192 6.2E-21 T 29-03-2018 MSG_RS20650 ff8823da55bd7c4d2049b8fc7ff73b14 207 SUPERFAMILY SSF48498 79 189 4.77E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS08465 dea2c8e1307fe8f5c5897250605d5cab 339 SUPERFAMILY SSF53474 42 323 2.8E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08465 dea2c8e1307fe8f5c5897250605d5cab 339 Pfam PF12146 Serine aminopeptidase, S33 41 255 2.6E-13 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MSG_RS08465 dea2c8e1307fe8f5c5897250605d5cab 339 Gene3D G3DSA:3.40.50.1820 22 327 2.5E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 287 303 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 SUPERFAMILY SSF103473 3 413 9.02E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 Gene3D G3DSA:1.20.1250.20 2 212 1.2E-20 T 29-03-2018 MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 Gene3D G3DSA:1.20.1250.20 213 418 5.4E-23 T 29-03-2018 MSG_RS18910 39d9b43436c4993e985ef0c72da94ab0 418 Pfam PF07690 Major Facilitator Superfamily 38 371 1.7E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.1E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.1E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.1E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.1E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 42 284 8.5E-91 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.355 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.1E-52 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 SUPERFAMILY SSF55920 6 284 9.68E-89 T 29-03-2018 IPR000994 Peptidase M24 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MSG_RS08425 72432de5172d3e07e1923985be0c9995 285 Gene3D G3DSA:3.90.230.10 36 285 6.2E-89 T 29-03-2018 MSG_RS22780 d8ec6acc5f58957dae8cae4191f89829 475 Pfam PF13354 Beta-lactamase enzyme family 208 350 5.2E-21 T 29-03-2018 MSG_RS22780 d8ec6acc5f58957dae8cae4191f89829 475 Gene3D G3DSA:3.40.710.10 177 473 1.1E-19 T 29-03-2018 MSG_RS22780 d8ec6acc5f58957dae8cae4191f89829 475 SUPERFAMILY SSF56601 72 314 5.99E-38 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS22780 d8ec6acc5f58957dae8cae4191f89829 475 SUPERFAMILY SSF56601 364 471 5.99E-38 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 237 544 1.3E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 Gene3D G3DSA:3.40.50.2300 6 159 9.6E-22 T 29-03-2018 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 SMART SM00448 14 136 5.0E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 SUPERFAMILY SSF52172 13 150 1.14E-21 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 Gene3D G3DSA:3.50.50.60 381 558 1.2E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 Gene3D G3DSA:3.50.50.60 236 379 3.9E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 Pfam PF00072 Response regulator receiver domain 17 129 1.8E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 SUPERFAMILY SSF51905 235 496 5.11E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 431 447 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 292 302 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 260 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 518 536 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 377 401 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 286 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 339 347 2.1E-37 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 508 530 1.6E-24 T 29-03-2018 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 258 1.6E-24 T 29-03-2018 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 483 1.6E-24 T 29-03-2018 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 399 1.6E-24 T 29-03-2018 MSG_RS04815 5f4808ad8be856c7f8585cafd39723e6 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 338 356 1.6E-24 T 29-03-2018 MSG_RS14925 fdab166fe6e42fb29fe14c1a9b5e9660 259 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 203 1.4E-44 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS14925 fdab166fe6e42fb29fe14c1a9b5e9660 259 Gene3D G3DSA:3.40.50.1240 1 213 1.5E-37 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS14925 fdab166fe6e42fb29fe14c1a9b5e9660 259 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 2 208 7.0E-99 T 29-03-2018 IPR022492 Phosphomutase MSMEG4193, putative MSG_RS14925 fdab166fe6e42fb29fe14c1a9b5e9660 259 SMART SM00855 2 164 6.1E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS14925 fdab166fe6e42fb29fe14c1a9b5e9660 259 SUPERFAMILY SSF53254 2 205 1.24E-42 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS07670 3505bd8b9bf7d84e6767c740dce5f9f0 337 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 4 328 1.0E-70 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS07670 3505bd8b9bf7d84e6767c740dce5f9f0 337 SUPERFAMILY SSF51726 8 331 2.88E-30 T 29-03-2018 MSG_RS07670 3505bd8b9bf7d84e6767c740dce5f9f0 337 Gene3D G3DSA:3.20.20.210 59 336 2.0E-42 T 29-03-2018 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 1.6E-20 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 Gene3D G3DSA:3.40.50.2020 156 316 1.0E-41 T 29-03-2018 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 323 4.8E-122 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 Gene3D G3DSA:3.40.50.2020 12 155 5.0E-61 T 29-03-2018 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 SMART SM01400 12 128 7.3E-71 T 29-03-2018 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 4.2E-46 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 SUPERFAMILY SSF53271 77 314 2.74E-61 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS19885 5550290b3afd3f98e881e0a2b04258ac 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 45.626 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MSG_RS16815 f5f673eb72b7d481ef6cadca42efa356 306 Gene3D G3DSA:1.10.620.20 2 246 1.9E-23 T 29-03-2018 MSG_RS16815 f5f673eb72b7d481ef6cadca42efa356 306 SUPERFAMILY SSF47240 10 287 2.48E-45 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS10025 846815e33d467f263de9bffdee3f489a 395 Pfam PF01266 FAD dependent oxidoreductase 6 355 6.6E-58 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS10025 846815e33d467f263de9bffdee3f489a 395 Gene3D G3DSA:3.50.50.60 3 385 6.9E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10025 846815e33d467f263de9bffdee3f489a 395 SUPERFAMILY SSF51905 5 220 3.95E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS10025 846815e33d467f263de9bffdee3f489a 395 SUPERFAMILY SSF51905 317 377 3.95E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12900 e5192926e7070d9b6f13f91ac48cbdd8 694 Gene3D G3DSA:3.40.190.10 164 467 7.4E-4 T 29-03-2018 MSG_RS12900 e5192926e7070d9b6f13f91ac48cbdd8 694 SUPERFAMILY SSF53300 510 680 8.34E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS12900 e5192926e7070d9b6f13f91ac48cbdd8 694 Gene3D G3DSA:3.40.50.410 478 694 2.8E-10 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS12900 e5192926e7070d9b6f13f91ac48cbdd8 694 Pfam PF13531 Bacterial extracellular solute-binding protein 179 461 5.2E-16 T 29-03-2018 MSG_RS24305 d0bd2d95a870fad052395fd57fa985e6 263 Gene3D G3DSA:3.20.180.10 163 252 6.4E-19 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 MSG_RS24305 d0bd2d95a870fad052395fd57fa985e6 263 SUPERFAMILY SSF50475 10 257 6.18E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS24305 d0bd2d95a870fad052395fd57fa985e6 263 Pfam PF10615 Protein of unknown function (DUF2470) 178 245 1.9E-6 T 29-03-2018 IPR019595 Domain of unknown function DUF2470 MSG_RS21115 667e41c458d5181236fc91080e13ad64 346 Gene3D G3DSA:1.20.1480.30 177 275 1.3E-4 T 29-03-2018 MSG_RS21115 667e41c458d5181236fc91080e13ad64 346 Pfam PF02470 MlaD protein 40 113 6.1E-17 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS21115 667e41c458d5181236fc91080e13ad64 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 294 2.7E-66 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS15450 76847699e66e604f7f1cb44e9283da23 140 Pfam PF06271 RDD family 25 117 3.0E-8 T 29-03-2018 IPR010432 RDD MSG_RS15450 76847699e66e604f7f1cb44e9283da23 140 PIRSF PIRSF021697 2 140 1.1E-54 T 29-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane MSG_RS05220 5acf14f6a7e6f3d94db51cdc98ac9a4c 465 Gene3D G3DSA:3.30.559.10 18 193 6.4E-7 T 29-03-2018 MSG_RS05220 5acf14f6a7e6f3d94db51cdc98ac9a4c 465 Pfam PF06974 Protein of unknown function (DUF1298) 280 420 6.4E-16 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS05220 5acf14f6a7e6f3d94db51cdc98ac9a4c 465 SUPERFAMILY SSF52777 60 180 3.67E-7 T 29-03-2018 MSG_RS05220 5acf14f6a7e6f3d94db51cdc98ac9a4c 465 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 23 244 1.3E-36 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS03245 c7513f28f97d68c83205dca4c9d47489 171 SUPERFAMILY SSF109854 10 168 6.41E-29 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS03245 c7513f28f97d68c83205dca4c9d47489 171 Gene3D G3DSA:1.20.120.450 3 171 3.5E-30 T 29-03-2018 MSG_RS03245 c7513f28f97d68c83205dca4c9d47489 171 Pfam PF04978 Protein of unknown function (DUF664) 12 169 6.3E-32 T 29-03-2018 IPR007061 Protein of unknown function DUF664 MSG_RS12670 a441c34df401f3d07fd21dc0f1276ceb 99 SUPERFAMILY SSF140459 8 83 7.59E-24 T 29-03-2018 MSG_RS12670 a441c34df401f3d07fd21dc0f1276ceb 99 Pfam PF00934 PE family 1 93 5.6E-33 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS12670 a441c34df401f3d07fd21dc0f1276ceb 99 Gene3D G3DSA:1.10.287.1060 1 97 4.3E-4 T 29-03-2018 MSG_RS06510 b1151e42d6fdd016591159c7b3f55496 186 Gene3D G3DSA:1.20.120.520 4 169 5.4E-16 T 29-03-2018 MSG_RS06510 b1151e42d6fdd016591159c7b3f55496 186 Pfam PF01814 Hemerythrin HHE cation binding domain 12 123 1.5E-8 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 PIRSF PIRSF002181 3 147 3.0E-44 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 SUPERFAMILY SSF52161 5 144 8.24E-56 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 Pfam PF00572 Ribosomal protein L13 15 137 5.9E-52 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 Gene3D G3DSA:3.90.1180.10 1 147 2.1E-58 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 139 26.514 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MSG_RS04910 aa33d376fd52f7b2685e1c7923b2034f 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.7E-58 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS08675 2c24b20a44cf16b0c673199ad668933b 362 Gene3D G3DSA:3.40.50.720 1 182 3.2E-16 T 29-03-2018 MSG_RS08675 2c24b20a44cf16b0c673199ad668933b 362 SUPERFAMILY SSF51735 7 146 8.67E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08675 2c24b20a44cf16b0c673199ad668933b 362 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 9 77 3.2E-6 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS03485 045cd2f7d41f6b40cb216add8713c66d 322 ProDom PD133063 RV0493C/MT0513 MB0504C BLSR 19 322 4.0E-116 T 29-03-2018 MSG_RS18025 7bd21d6fc55ddbe64cd575b40caa68e8 358 Pfam PF01636 Phosphotransferase enzyme family 65 290 2.9E-15 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS18025 7bd21d6fc55ddbe64cd575b40caa68e8 358 Gene3D G3DSA:3.90.1200.10 135 355 3.9E-16 T 29-03-2018 MSG_RS18025 7bd21d6fc55ddbe64cd575b40caa68e8 358 SUPERFAMILY SSF56112 13 328 2.92E-28 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 9.7E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 Pfam PF00440 Bacterial regulatory proteins, tetR family 259 302 4.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 SUPERFAMILY SSF46689 27 99 1.05E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 Gene3D G3DSA:1.10.357.10 250 436 1.4E-23 T 29-03-2018 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 SUPERFAMILY SSF48498 107 217 1.34E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 Gene3D G3DSA:1.10.357.10 77 221 9.2E-17 T 29-03-2018 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 Gene3D G3DSA:1.10.10.60 1 76 1.3E-15 T 29-03-2018 MSG_RS19285 c1c9a9302cfd0253992f40e366e84736 437 SUPERFAMILY SSF46689 250 327 5.64E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14440 1cb272d831db5d7ba3a96eda73fd7255 280 Gene3D G3DSA:1.10.3720.10 3 267 8.5E-47 T 29-03-2018 MSG_RS14440 1cb272d831db5d7ba3a96eda73fd7255 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 273 1.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS14440 1cb272d831db5d7ba3a96eda73fd7255 280 SUPERFAMILY SSF161098 9 277 4.84E-73 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 SMART SM00829 20 300 4.4E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 SUPERFAMILY SSF51735 151 259 2.04E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 SUPERFAMILY SSF50129 92 189 1.03E-23 T 29-03-2018 IPR011032 GroES-like MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 SUPERFAMILY SSF50129 14 65 1.03E-23 T 29-03-2018 IPR011032 GroES-like MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 Gene3D G3DSA:3.40.50.720 185 283 2.8E-8 T 29-03-2018 MSG_RS16285 e2543cef31a4271081cae6c106c9adf8 381 Gene3D G3DSA:3.90.180.10 6 184 1.8E-26 T 29-03-2018 MSG_RS23150 8b2c957818356255406299c4be53d6b8 53 Pfam PF13783 Domain of unknown function (DUF4177) 7 42 4.6E-6 T 29-03-2018 IPR025234 Protein of unknown function DUF4177 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 7.2E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 7.2E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 7.2E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 7.2E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 7.2E-49 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 513 3.7E-201 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 Gene3D G3DSA:3.40.50.720 26 216 3.6E-66 T 29-03-2018 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 1.7E-109 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 SUPERFAMILY SSF55347 205 512 2.26E-110 T 29-03-2018 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 SUPERFAMILY SSF51735 18 218 2.56E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 513 87.878 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 215 6.5E-61 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 PIRSF PIRSF000110 6 514 6.4E-176 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS10505 dff50b23db2d5b2490e7ab7c7a5a34f3 514 Gene3D G3DSA:3.30.360.10 217 514 3.8E-123 T 29-03-2018 MSG_RS14295 d20fc7349b10964f419475f6c84d5bf9 434 Pfam PF01757 Acyltransferase family 15 356 1.1E-14 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 841 879 1.9E-4 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Gene3D G3DSA:3.40.640.10 290 628 2.8E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 556 747 4.4E-23 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 290 514 8.2E-49 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Gene3D G3DSA:3.90.1150.10 629 780 9.3E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 Gene3D G3DSA:3.90.100.10 781 914 2.4E-24 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 SUPERFAMILY SSF53383 551 766 7.39E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS09960 8feabc0254e0da506c27757d8cb707e4 949 SUPERFAMILY SSF53383 290 512 7.39E-76 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS02940 2471077caa804aed67d053a378b3150e 364 Pfam PF00296 Luciferase-like monooxygenase 30 273 5.3E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02940 2471077caa804aed67d053a378b3150e 364 PIRSF PIRSF000337 2 274 9.0E-57 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS02940 2471077caa804aed67d053a378b3150e 364 PIRSF PIRSF000337 278 363 2.8E-11 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS02940 2471077caa804aed67d053a378b3150e 364 Gene3D G3DSA:3.20.20.30 278 364 1.5E-13 T 29-03-2018 MSG_RS02940 2471077caa804aed67d053a378b3150e 364 SUPERFAMILY SSF51679 1 353 3.09E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02940 2471077caa804aed67d053a378b3150e 364 Gene3D G3DSA:3.20.20.30 1 277 2.1E-46 T 29-03-2018 MSG_RS04590 8127f15f521db6203c82637474145040 228 SUPERFAMILY SSF54768 47 114 4.71E-21 T 29-03-2018 MSG_RS04590 8127f15f521db6203c82637474145040 228 ProSitePatterns PS00585 Ribosomal protein S5 signature. 66 98 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MSG_RS04590 8127f15f521db6203c82637474145040 228 Gene3D G3DSA:3.30.230.10 114 204 1.5E-28 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS04590 8127f15f521db6203c82637474145040 228 Pfam PF03719 Ribosomal protein S5, C-terminal domain 125 195 6.9E-28 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MSG_RS04590 8127f15f521db6203c82637474145040 228 Pfam PF00333 Ribosomal protein S5, N-terminal domain 51 113 1.2E-25 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MSG_RS04590 8127f15f521db6203c82637474145040 228 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 201 34.135 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04590 8127f15f521db6203c82637474145040 228 Gene3D G3DSA:3.30.160.20 48 108 2.0E-24 T 29-03-2018 MSG_RS04590 8127f15f521db6203c82637474145040 228 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 47 201 3.8E-68 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04590 8127f15f521db6203c82637474145040 228 SUPERFAMILY SSF54211 117 196 6.57E-24 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS09645 528bffd4313d40860d0df73651e3fe6d 143 ProDom PD031728 MEMBRANE PROBABLE RV2599/MT2674 PRECURSOR TRANSMEMBRANE B1177_F3_123 SIGNAL 1 113 4.0E-31 T 29-03-2018 MSG_RS09645 528bffd4313d40860d0df73651e3fe6d 143 Pfam PF14042 Domain of unknown function (DUF4247) 21 134 2.7E-29 T 29-03-2018 IPR025341 Protein of unknown function DUF4247 MSG_RS09610 7e1637240ad94c33e89772e463df0df2 358 Gene3D G3DSA:1.10.287.1060 23 104 2.2E-8 T 29-03-2018 MSG_RS09610 7e1637240ad94c33e89772e463df0df2 358 Pfam PF00823 PPE family 8 162 1.6E-59 T 29-03-2018 IPR000030 PPE family MSG_RS09610 7e1637240ad94c33e89772e463df0df2 358 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 277 357 3.7E-6 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS09610 7e1637240ad94c33e89772e463df0df2 358 SUPERFAMILY SSF140459 4 174 6.8E-60 T 29-03-2018 MSG_RS01040 a84813b494e2bb0aff41ad09db365b46 454 Pfam PF00171 Aldehyde dehydrogenase family 162 299 2.1E-5 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS01040 a84813b494e2bb0aff41ad09db365b46 454 SUPERFAMILY SSF53720 39 440 1.54E-19 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS01040 a84813b494e2bb0aff41ad09db365b46 454 Gene3D G3DSA:3.40.605.10 19 286 2.7E-18 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 SUPERFAMILY SSF100920 358 514 3.79E-64 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Gene3D G3DSA:3.30.420.40 172 334 1.7E-48 T 29-03-2018 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 584 5.2E-274 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 443 459 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 362 381 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 339 359 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.7E-76 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Pfam PF00012 Hsp70 protein 4 585 4.9E-245 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Gene3D G3DSA:2.60.34.10 364 505 1.4E-71 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Gene3D G3DSA:3.30.420.40 1 171 7.0E-68 T 29-03-2018 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 SUPERFAMILY SSF53067 162 356 1.36E-63 T 29-03-2018 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 617 36.309 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 SUPERFAMILY SSF53067 4 160 5.99E-58 T 29-03-2018 MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 SUPERFAMILY SSF100934 481 585 1.7E-14 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MSG_RS02735 ef6f607545ec881ddf620e978aec1a50 622 Gene3D G3DSA:1.20.1270.10 506 598 1.0E-20 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 Gene3D G3DSA:3.40.630.10 4 196 8.4E-34 T 29-03-2018 MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 Pfam PF07687 Peptidase dimerisation domain 191 340 5.5E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 Pfam PF01546 Peptidase family M20/M25/M40 82 432 2.8E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 Gene3D G3DSA:3.30.70.360 197 351 3.3E-38 T 29-03-2018 MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 SUPERFAMILY SSF53187 2 193 1.07E-56 T 29-03-2018 MSG_RS17625 eab064e211fed4fc05ad9c73767463db 441 SUPERFAMILY SSF53187 354 441 1.07E-56 T 29-03-2018 MSG_RS07075 985f1a1c8d0b56b5af9d3c9c6c7b658c 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 120 1.5E-26 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MSG_RS07075 985f1a1c8d0b56b5af9d3c9c6c7b658c 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 9 126 18.527 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MSG_RS11665 1b730ac7efec1722bf2e7c7ce24a60df 204 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 4 186 2.7E-55 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MSG_RS11665 1b730ac7efec1722bf2e7c7ce24a60df 204 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 1 189 27.634 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MSG_RS11665 1b730ac7efec1722bf2e7c7ce24a60df 204 Gene3D G3DSA:3.10.300.10 1 197 1.1E-54 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MSG_RS11665 1b730ac7efec1722bf2e7c7ce24a60df 204 SUPERFAMILY SSF50486 3 196 6.91E-54 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MSG_RS11665 1b730ac7efec1722bf2e7c7ce24a60df 204 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 3 189 8.2E-62 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 Gene3D G3DSA:3.40.50.1100 216 421 9.7E-42 T 29-03-2018 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 102 116 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 Gene3D G3DSA:3.40.50.1100 91 215 5.7E-41 T 29-03-2018 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 Gene3D G3DSA:3.40.50.1100 30 90 7.1E-7 T 29-03-2018 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 23 412 51.791 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 PIRSF PIRSF001413 18 416 1.5E-159 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 28 410 9.8E-185 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 SUPERFAMILY SSF53686 24 411 3.14E-147 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS11230 448b55fb903cd064ad9d7e9496762fb4 421 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 399 5.4E-53 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 SMART SM00984 320 422 4.8E-46 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 PIRSF PIRSF500134 1 438 1.3E-181 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Gene3D G3DSA:1.20.5.100 200 222 7.5E-16 T 29-03-2018 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 PIRSF PIRSF000124 1 437 1.2E-146 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 418 9.9E-137 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 SUPERFAMILY SSF51735 2 190 5.87E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Gene3D G3DSA:3.40.50.720 223 434 6.2E-74 T 29-03-2018 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 422 1.9E-30 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 291 2.7E-38 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 SUPERFAMILY SSF48179 199 293 3.57E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 SUPERFAMILY SSF52413 312 433 1.83E-35 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 182 7.2E-66 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MSG_RS20015 1946c23eb1d478e1708c94493ac704ce 438 Gene3D G3DSA:3.40.50.720 1 196 1.2E-60 T 29-03-2018 MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 Gene3D G3DSA:3.40.50.10190 239 309 1.8E-6 T 29-03-2018 IPR001357 BRCT domain MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 SUPERFAMILY SSF53098 20 194 6.58E-42 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 22 181 4.5E-22 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 Pfam PF00929 Exonuclease 22 174 5.9E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 SUPERFAMILY SSF52113 233 306 8.18E-8 T 29-03-2018 IPR001357 BRCT domain MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 SMART SM00479 19 184 6.5E-37 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MSG_RS23420 c6ccc478d02fb67a64ef449d96b05662 333 Gene3D G3DSA:3.30.420.10 19 185 1.6E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS22515 3fcf61174bd677a9af835a04d9f5ab2c 150 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 38 149 2.0E-36 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS22515 3fcf61174bd677a9af835a04d9f5ab2c 150 Pfam PF04075 F420H(2)-dependent quinone reductase 24 149 2.5E-47 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS22515 3fcf61174bd677a9af835a04d9f5ab2c 150 SUPERFAMILY SSF50475 40 143 3.55E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS22515 3fcf61174bd677a9af835a04d9f5ab2c 150 Gene3D G3DSA:2.30.110.10 15 150 2.1E-41 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 Pfam PF00069 Protein kinase domain 10 221 1.8E-41 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 Gene3D G3DSA:3.30.200.20 4 107 4.4E-21 T 29-03-2018 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 SMART SM00220 10 272 6.3E-56 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 Gene3D G3DSA:1.10.510.10 108 315 1.5E-38 T 29-03-2018 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 SUPERFAMILY SSF56112 9 314 7.69E-65 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS16270 9a03bd8153d0ff226649a6416f1aedce 557 Pfam PF14032 PknH-like extracellular domain 369 553 3.2E-33 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Pfam PF11941 Domain of unknown function (DUF3459) 446 520 4.4E-7 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Gene3D G3DSA:3.20.20.80 340 462 4.8E-20 T 29-03-2018 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Gene3D G3DSA:2.60.40.1180 480 521 5.9E-4 T 29-03-2018 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Pfam PF00128 Alpha amylase, catalytic domain 29 372 2.5E-79 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Gene3D G3DSA:3.90.400.10 106 178 4.0E-30 T 29-03-2018 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 SMART SM00642 14 399 3.4E-121 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Gene3D G3DSA:3.20.20.470 179 339 8.3E-33 T 29-03-2018 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 Gene3D G3DSA:3.20.20.470 1 96 7.1E-33 T 29-03-2018 MSG_RS17295 d7929a32e37eb138c56f16d9aff31bc4 521 SUPERFAMILY SSF51445 5 458 2.22E-124 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 PIRSF PIRSF000362 1 454 8.2E-164 T 29-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 Gene3D G3DSA:3.50.50.60 106 324 3.4E-72 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 Gene3D G3DSA:3.40.50.720 1 105 5.4E-10 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 226 5.8E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 4.8E-14 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 PRINTS PR00419 Adrenodoxin reductase family signature 78 88 4.8E-14 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 PRINTS PR00419 Adrenodoxin reductase family signature 150 164 4.8E-14 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 SUPERFAMILY SSF51971 309 440 2.16E-9 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 SUPERFAMILY SSF51971 3 216 1.41E-60 T 29-03-2018 MSG_RS06860 d07959f8c3dddd4c81e40d692a1b6870 454 SUPERFAMILY SSF51971 264 324 1.41E-60 T 29-03-2018 MSG_RS09605 393a31da56bb78b090f1f15be39fa8e9 406 SUPERFAMILY SSF53474 112 278 9.58E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09605 393a31da56bb78b090f1f15be39fa8e9 406 Pfam PF00934 PE family 1 92 2.0E-25 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS09605 393a31da56bb78b090f1f15be39fa8e9 406 SUPERFAMILY SSF140459 9 83 2.43E-19 T 29-03-2018 MSG_RS09605 393a31da56bb78b090f1f15be39fa8e9 406 Gene3D G3DSA:3.40.50.1820 93 364 1.1E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09605 393a31da56bb78b090f1f15be39fa8e9 406 Pfam PF08237 PE-PPE domain 143 362 1.4E-53 T 29-03-2018 IPR013228 PE-PPE, C-terminal MSG_RS20205 71be52cad3d891849eea7eeccb392b14 112 Pfam PF09723 Zinc ribbon domain 2 40 8.3E-13 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS20205 71be52cad3d891849eea7eeccb392b14 112 SMART SM00834 2 41 3.7E-11 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS20205 71be52cad3d891849eea7eeccb392b14 112 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 9.2E-18 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MSG_RS01030 50439aa4d31e3ddc9e7a4c1e6f44c9c6 317 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 46 280 4.1E-46 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 322 349 3.4E-7 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 5 21 3.4E-7 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 30 54 3.4E-7 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 396 409 3.4E-7 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 115 131 3.4E-7 T 29-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 Gene3D G3DSA:3.50.50.60 161 485 2.0E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 SUPERFAMILY SSF51905 293 410 5.31E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 SUPERFAMILY SSF51905 7 226 5.31E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 Pfam PF00743 Flavin-binding monooxygenase-like 7 340 3.5E-15 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS01680 13940e72882b37b38c60cae834190fd2 504 Gene3D G3DSA:3.50.50.60 4 160 3.5E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18970 9d0e69d21b1bd592b4c9398c2fc70e96 393 PIRSF PIRSF000429 10 344 4.6E-21 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS18970 9d0e69d21b1bd592b4c9398c2fc70e96 393 SUPERFAMILY SSF53901 265 382 8.96E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18970 9d0e69d21b1bd592b4c9398c2fc70e96 393 Gene3D G3DSA:3.40.47.10 150 388 2.3E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18970 9d0e69d21b1bd592b4c9398c2fc70e96 393 Gene3D G3DSA:3.40.47.10 12 138 3.4E-4 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS18970 9d0e69d21b1bd592b4c9398c2fc70e96 393 SUPERFAMILY SSF53901 11 236 2.77E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 253 2.9E-50 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 Gene3D G3DSA:3.40.47.10 5 266 2.0E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 SUPERFAMILY SSF53901 13 259 1.58E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 SMART SM00825 Beta-ketoacyl synthase 14 407 9.3E-12 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 Gene3D G3DSA:3.40.47.10 270 416 3.6E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 373 6.0E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS15735 989c857a081e22ed4d7d7c81fb565d91 416 SUPERFAMILY SSF53901 222 416 1.8E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 247 3.2E-113 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 PIRSF PIRSF000709 4 118 8.7E-6 T 29-03-2018 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 PIRSF PIRSF000709 138 214 0.0082 T 29-03-2018 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 4 231 42.065 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 207 1.6E-31 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 SUPERFAMILY SSF53254 5 224 1.94E-69 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 SMART SM00855 6 190 1.1E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MSG_RS03465 d77bf0187e1ce514b7be158932826735 249 Gene3D G3DSA:3.40.50.1240 3 249 2.5E-58 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 Pfam PF00890 FAD binding domain 14 551 8.8E-92 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 SUPERFAMILY SSF51905 510 572 4.87E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 SUPERFAMILY SSF51905 13 125 4.87E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 SUPERFAMILY SSF51905 204 324 4.87E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 SUPERFAMILY SSF56425 319 504 4.19E-32 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 Gene3D G3DSA:3.50.50.60 8 568 9.4E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 527 542 6.9E-8 T 29-03-2018 MSG_RS21455 8ebdac81c1b490ac8554e8e20bc29f2e 580 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 6.9E-8 T 29-03-2018 MSG_RS24675 2da799366467251636ebe4398be16d28 249 Gene3D G3DSA:3.40.630.30 4 222 4.0E-8 T 29-03-2018 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 SUPERFAMILY SSF46689 8 89 8.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.9E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 Gene3D G3DSA:1.10.10.60 52 192 4.2E-10 T 29-03-2018 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18975 68387c9d33badf13ad9edd9434acffe4 202 Gene3D G3DSA:1.10.10.60 11 51 3.8E-17 T 29-03-2018 MSG_RS10070 1a5eb61325f59168672e17bec5c0ea59 63 SUPERFAMILY SSF54862 3 61 7.73E-11 T 29-03-2018 MSG_RS10070 1a5eb61325f59168672e17bec5c0ea59 63 Pfam PF13459 4Fe-4S single cluster domain 5 61 3.8E-13 T 29-03-2018 MSG_RS10070 1a5eb61325f59168672e17bec5c0ea59 63 Gene3D G3DSA:3.30.70.20 1 63 1.6E-8 T 29-03-2018 MSG_RS00800 7320e7f9a7d1af6e23cc7cb008d6f6a2 406 PIRSF PIRSF000429 3 396 2.4E-14 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS00800 7320e7f9a7d1af6e23cc7cb008d6f6a2 406 SUPERFAMILY SSF53901 255 395 5.07E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00800 7320e7f9a7d1af6e23cc7cb008d6f6a2 406 Gene3D G3DSA:3.40.47.10 163 395 4.0E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00800 7320e7f9a7d1af6e23cc7cb008d6f6a2 406 SUPERFAMILY SSF53901 34 249 7.81E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 SMART SM00862 164 237 2.0E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 SUPERFAMILY SSF52172 22 146 3.56E-34 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 SUPERFAMILY SSF46894 145 237 2.49E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 Gene3D G3DSA:3.40.50.2300 21 139 1.1E-27 T 29-03-2018 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 Gene3D G3DSA:1.10.10.10 140 241 1.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 Pfam PF00072 Response regulator receiver domain 24 132 2.7E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 237 1.5E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS16240 90a6e2f8fb382c7ffb8b60af294fef97 242 SMART SM00448 22 132 4.8E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 29 302 2.5E-46 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 140 164 7.4E-5 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 103 119 7.4E-5 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 189 207 7.4E-5 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 259 278 7.4E-5 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14845 a23ec331936b7e0e15a1f2653df75ca5 351 Pfam PF02470 MlaD protein 51 125 1.4E-15 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Pfam PF10415 Fumarase C C-terminus 408 464 1.9E-18 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Gene3D G3DSA:1.20.200.10 137 415 9.2E-80 T 29-03-2018 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Gene3D G3DSA:1.10.40.30 416 469 7.1E-23 T 29-03-2018 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 9.8E-35 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 9.8E-35 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 9.8E-35 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 9.8E-35 T 29-03-2018 IPR000362 Fumarate lyase family MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 SUPERFAMILY SSF48557 10 465 3.61E-139 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Pfam PF00206 Lyase 18 342 3.1E-102 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Hamap MF_00743 Fumarate hydratase class II [fumC]. 10 466 80.219 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MSG_RS19545 849e6e92753307fdc49526a118c29d78 473 Gene3D G3DSA:1.10.275.10 8 136 1.9E-52 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 Gene3D G3DSA:3.30.420.40 107 246 1.0E-22 T 29-03-2018 MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 SUPERFAMILY SSF46785 36 103 1.91E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 Gene3D G3DSA:1.10.10.10 32 104 9.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 Pfam PF00480 ROK family 110 380 1.4E-16 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 SUPERFAMILY SSF53067 109 404 3.46E-28 T 29-03-2018 MSG_RS03450 cc063caabbd03102bb9552d45ea74b46 437 Gene3D G3DSA:3.30.420.40 247 392 2.5E-19 T 29-03-2018 MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 SUPERFAMILY SSF56059 102 309 3.36E-36 T 29-03-2018 MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 Pfam PF02222 ATP-grasp domain 112 288 1.7E-22 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 SUPERFAMILY SSF51246 335 385 2.82E-5 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 Gene3D G3DSA:3.30.470.20 194 386 1.3E-24 T 29-03-2018 MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 SUPERFAMILY SSF52440 2 100 3.74E-17 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 Gene3D G3DSA:3.30.1490.20 119 187 5.6E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS02875 bc79cd5af411e1b32949bf0201d1bd94 397 Gene3D G3DSA:3.40.50.20 1 118 4.4E-14 T 29-03-2018 MSG_RS13105 687e896d0844c5c9d5bd994fa7bbfe6b 144 Pfam PF08837 Protein of unknown function (DUF1810) 8 142 2.5E-58 T 29-03-2018 IPR014937 Protein of unknown function DUF1810 MSG_RS13105 687e896d0844c5c9d5bd994fa7bbfe6b 144 SUPERFAMILY SSF140736 6 143 3.79E-59 T 29-03-2018 IPR014937 Protein of unknown function DUF1810 MSG_RS13105 687e896d0844c5c9d5bd994fa7bbfe6b 144 PIRSF PIRSF008546 3 144 2.4E-64 T 29-03-2018 IPR014937 Protein of unknown function DUF1810 MSG_RS22905 2905542c4f63fca950d04a9df78671e2 217 SUPERFAMILY SSF53271 38 216 1.97E-51 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS22905 2905542c4f63fca950d04a9df78671e2 217 Gene3D G3DSA:3.40.50.2020 32 217 4.2E-41 T 29-03-2018 MSG_RS22905 2905542c4f63fca950d04a9df78671e2 217 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 44 211 4.7E-67 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MSG_RS22905 2905542c4f63fca950d04a9df78671e2 217 Pfam PF00156 Phosphoribosyl transferase domain 48 198 1.5E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS14555 28ce52ef6e5bbd12734a5359f0d6879a 692 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 102 609 14.422 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MSG_RS14555 28ce52ef6e5bbd12734a5359f0d6879a 692 Gene3D G3DSA:3.60.110.10 314 605 6.0E-34 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS14555 28ce52ef6e5bbd12734a5359f0d6879a 692 SUPERFAMILY SSF56317 331 602 4.84E-38 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS14555 28ce52ef6e5bbd12734a5359f0d6879a 692 Pfam PF00795 Carbon-nitrogen hydrolase 399 590 7.0E-13 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS14555 28ce52ef6e5bbd12734a5359f0d6879a 692 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 157 571 2.5E-92 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 SUPERFAMILY SSF51735 168 267 2.23E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 SUPERFAMILY SSF51735 3 133 2.23E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 Gene3D G3DSA:3.40.50.720 2 267 6.3E-45 T 29-03-2018 MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 173 264 4.2E-14 T 29-03-2018 MSG_RS00955 f02b3caee4d55fc5b11e92bcd3a450b5 278 Pfam PF00106 short chain dehydrogenase 4 132 4.2E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS19695 e39626e8b9395be1204d61519252c221 139 Gene3D G3DSA:3.40.190.10 1 136 4.0E-4 T 29-03-2018 MSG_RS19695 e39626e8b9395be1204d61519252c221 139 Pfam PF17301 Putative lipoprotein LpqV 26 139 3.5E-48 T 29-03-2018 IPR020377 Uncharacterised protein family LpqV MSG_RS19695 e39626e8b9395be1204d61519252c221 139 ProDom PD076648 LIPOPROTEIN LPQV PALMITATE MEMBRANE PRECURSOR SIGNAL 19 120 6.0E-29 T 29-03-2018 IPR020377 Uncharacterised protein family LpqV MSG_RS15405 2378d8bdf52ccb6026daec723295d37a 148 SUPERFAMILY SSF55961 3 142 4.62E-20 T 29-03-2018 MSG_RS15405 2378d8bdf52ccb6026daec723295d37a 148 Gene3D G3DSA:3.30.530.20 1 148 1.4E-17 T 29-03-2018 IPR023393 START-like domain MSG_RS07405 19a900dd026850485455cb1b983e5913 184 Gene3D G3DSA:1.10.10.60 1 37 5.5E-12 T 29-03-2018 MSG_RS07405 19a900dd026850485455cb1b983e5913 184 Gene3D G3DSA:1.10.357.10 38 173 1.3E-12 T 29-03-2018 MSG_RS07405 19a900dd026850485455cb1b983e5913 184 ProSitePatterns PS01081 TetR-type HTH domain signature. 8 39 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS07405 19a900dd026850485455cb1b983e5913 184 SUPERFAMILY SSF46689 3 54 2.6E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07405 19a900dd026850485455cb1b983e5913 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 39 1.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 224 1.2E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Gene3D G3DSA:2.40.110.10 135 239 1.5E-29 T 29-03-2018 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 130 2.5E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Gene3D G3DSA:1.10.540.10 1 134 6.2E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 4.5E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 SUPERFAMILY SSF56645 3 260 1.31E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 SUPERFAMILY SSF47203 245 401 1.01E-37 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS23870 862bb950f2d3d58cdc5263076b7ffe03 430 Gene3D G3DSA:1.20.140.10 240 408 1.5E-35 T 29-03-2018 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 SUPERFAMILY SSF53800 4 318 2.45E-81 T 29-03-2018 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 ProSitePatterns PS00534 Ferrochelatase signature. 167 187 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 Gene3D G3DSA:3.40.50.1400 151 281 9.2E-44 T 29-03-2018 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 Pfam PF00762 Ferrochelatase 4 297 5.7E-91 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 TIGRFAM TIGR00109 hemH: ferrochelatase 5 299 1.3E-41 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 Hamap MF_00323 Ferrochelatase [hemH]. 2 299 31.132 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MSG_RS10685 15e3a8ac029d5acef3d2474d8e662c15 339 Gene3D G3DSA:3.40.50.1400 3 150 5.2E-27 T 29-03-2018 MSG_RS06220 3d371259a9d775d764cfd824518d435c 406 Gene3D G3DSA:2.140.10.10 5 215 3.1E-7 T 29-03-2018 MSG_RS06220 3d371259a9d775d764cfd824518d435c 406 Gene3D G3DSA:2.140.10.10 250 405 0.0014 T 29-03-2018 MSG_RS01280 cc21bdef9bca314a2877495e4f81e1ae 165 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 157 1.5E-24 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 MSG_RS01280 cc21bdef9bca314a2877495e4f81e1ae 165 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 152 1.0E-25 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MSG_RS01280 cc21bdef9bca314a2877495e4f81e1ae 165 SUPERFAMILY SSF56300 1 163 7.59E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS01280 cc21bdef9bca314a2877495e4f81e1ae 165 Gene3D G3DSA:3.60.21.10 1 156 4.1E-16 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 Gene3D G3DSA:3.30.9.10 206 359 3.0E-18 T 29-03-2018 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 Pfam PF01266 FAD dependent oxidoreductase 104 356 3.1E-23 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 Pfam PF01266 FAD dependent oxidoreductase 41 95 5.5E-8 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 SUPERFAMILY SSF51971 23 94 4.12E-5 T 29-03-2018 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 Gene3D G3DSA:3.40.50.720 101 205 3.0E-7 T 29-03-2018 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 SUPERFAMILY SSF51971 103 302 1.29E-19 T 29-03-2018 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 SUPERFAMILY SSF54373 289 354 4.45E-8 T 29-03-2018 MSG_RS11195 94d802a190fb305d855f3bbd562e602a 360 Gene3D G3DSA:3.40.50.720 3 95 1.8E-7 T 29-03-2018 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 Pfam PF00005 ABC transporter 23 197 3.0E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 Pfam PF00005 ABC transporter 353 481 3.7E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 SMART SM00382 28 242 4.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 SMART SM00382 360 525 9.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 SUPERFAMILY SSF52540 340 526 4.21E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 Gene3D G3DSA:3.40.50.300 1 303 1.8E-43 T 29-03-2018 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 Gene3D G3DSA:3.40.50.300 304 540 1.6E-50 T 29-03-2018 MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 SUPERFAMILY SSF52540 19 239 2.62E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10620 9b39ca6f51761dfae8e7814302d2a74c 542 Pfam PF12848 ABC transporter 242 314 3.2E-8 T 29-03-2018 IPR032781 ABC-transporter extension domain MSG_RS19805 5fde86bf06c2cf009ac79e858da632f9 556 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 554 4.0E-207 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MSG_RS19805 5fde86bf06c2cf009ac79e858da632f9 556 PIRSF PIRSF001294 3 556 3.6E-220 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MSG_RS19805 5fde86bf06c2cf009ac79e858da632f9 556 Pfam PF03814 Potassium-transporting ATPase A subunit 13 554 2.6E-227 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MSG_RS19805 5fde86bf06c2cf009ac79e858da632f9 556 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 556 32.352 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MSG_RS06745 75716b9ba71fa1a801a260a76a0c208b 260 SUPERFAMILY SSF52833 48 200 8.5E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS06745 75716b9ba71fa1a801a260a76a0c208b 260 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 49 191 4.5E-46 T 29-03-2018 MSG_RS06745 75716b9ba71fa1a801a260a76a0c208b 260 PIRSF PIRSF000216 22 250 3.1E-73 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06745 75716b9ba71fa1a801a260a76a0c208b 260 Gene3D G3DSA:3.40.30.10 110 200 2.8E-14 T 29-03-2018 MSG_RS15935 019c7cc413cc4aaf1bbe8c3de1d81e0f 233 SUPERFAMILY SSF51182 157 217 2.94E-5 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS15935 019c7cc413cc4aaf1bbe8c3de1d81e0f 233 SUPERFAMILY SSF51182 96 134 3.37E-6 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS15935 019c7cc413cc4aaf1bbe8c3de1d81e0f 233 SUPERFAMILY SSF51182 17 67 3.37E-6 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS15935 019c7cc413cc4aaf1bbe8c3de1d81e0f 233 Gene3D G3DSA:2.60.120.10 163 229 1.2E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS15935 019c7cc413cc4aaf1bbe8c3de1d81e0f 233 Gene3D G3DSA:2.60.120.10 11 77 4.1E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS20005 8ea0f9fc030dd59ad6133016de916aa8 402 SUPERFAMILY SSF53756 28 398 1.96E-66 T 29-03-2018 MSG_RS20005 8ea0f9fc030dd59ad6133016de916aa8 402 Gene3D G3DSA:3.40.50.2000 198 380 6.1E-38 T 29-03-2018 MSG_RS20005 8ea0f9fc030dd59ad6133016de916aa8 402 Pfam PF13439 Glycosyltransferase Family 4 28 197 4.7E-12 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS20005 8ea0f9fc030dd59ad6133016de916aa8 402 Pfam PF00534 Glycosyl transferases group 1 198 373 4.1E-26 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS20005 8ea0f9fc030dd59ad6133016de916aa8 402 Gene3D G3DSA:3.40.50.2000 5 197 4.9E-9 T 29-03-2018 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Pfam PF06071 Protein of unknown function (DUF933) 273 356 1.8E-38 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 357 42.25 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 SUPERFAMILY SSF52540 4 295 8.46E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 PIRSF PIRSF006641 1 357 2.0E-137 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.1E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Gene3D G3DSA:1.10.150.300 110 196 4.2E-21 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 357 1.1E-129 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 SUPERFAMILY SSF81271 273 357 1.5E-34 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Gene3D G3DSA:3.10.20.30 257 356 1.0E-43 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS19495 8830bee91300486864d6d74b54a15ffe 357 Gene3D G3DSA:3.40.50.300 2 80 4.5E-9 T 29-03-2018 MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 Pfam PF00266 Aminotransferase class-V 24 329 1.2E-17 T 29-03-2018 IPR000192 Aminotransferase class V domain MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 12 370 1.3E-210 T 29-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 Gene3D G3DSA:3.40.640.10 22 257 4.0E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 6 370 24.757 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 SUPERFAMILY SSF53383 13 369 3.59E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 Gene3D G3DSA:3.90.1150.10 258 370 7.5E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS20725 eac4d5994131c3e74f7b12cec47f1d45 370 PIRSF PIRSF000525 2 370 9.6E-81 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MSG_RS23450 e1df356dce8d651a5be97fd8ca893dac 257 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 45 246 6.4E-33 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS23450 e1df356dce8d651a5be97fd8ca893dac 257 SMART SM00646 126 247 1.9E-26 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MSG_RS23450 e1df356dce8d651a5be97fd8ca893dac 257 SUPERFAMILY SSF53187 42 250 9.73E-35 T 29-03-2018 MSG_RS23450 e1df356dce8d651a5be97fd8ca893dac 257 Gene3D G3DSA:3.40.630.40 24 257 3.2E-47 T 29-03-2018 MSG_RS13315 f055e923ef0869609b5a1881c2f9c2b0 139 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 27 134 4.6E-28 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MSG_RS13315 f055e923ef0869609b5a1881c2f9c2b0 139 Gene3D G3DSA:3.30.750.24 24 138 1.5E-12 T 29-03-2018 IPR002645 STAS domain MSG_RS13315 f055e923ef0869609b5a1881c2f9c2b0 139 SUPERFAMILY SSF52091 32 137 2.94E-16 T 29-03-2018 IPR002645 STAS domain MSG_RS13315 f055e923ef0869609b5a1881c2f9c2b0 139 Pfam PF01740 STAS domain 37 135 7.2E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Pfam PF00689 Cation transporting ATPase, C-terminus 676 839 6.8E-12 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF81665 22 130 1.96E-87 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF81665 239 332 1.96E-87 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF81665 642 841 1.96E-87 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Gene3D G3DSA:2.70.150.10 29 239 5.0E-34 T 29-03-2018 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Pfam PF00690 Cation transporter/ATPase, N-terminus 23 87 9.5E-14 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF56784 450 692 2.13E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF56784 337 356 2.13E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SMART SM00831 20 92 6.3E-15 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Pfam PF00122 E1-E2 ATPase 130 317 5.7E-42 T 29-03-2018 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 228 355 1.3E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 560 682 1.3E-24 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 20 841 8.3E-221 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Gene3D G3DSA:3.40.1110.10 301 500 5.8E-24 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 SUPERFAMILY SSF81653 131 236 3.53E-24 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Gene3D G3DSA:1.20.1110.10 529 843 6.2E-51 T 29-03-2018 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 752 773 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 651 666 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 669 680 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 802 823 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 251 267 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 268 287 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 701 714 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 PRINTS PR01836 Magnesium-transporting ATPase signature 721 737 8.4E-41 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MSG_RS05625 06b391722c805881e346916f6ca1b7b4 875 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 607 6.4E-18 T 29-03-2018 MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 SUPERFAMILY SSF53098 211 352 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 SUPERFAMILY SSF53098 158 168 9.23E-34 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 Gene3D G3DSA:1.10.10.10 8 92 3.1E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 Gene3D G3DSA:3.30.420.10 148 358 6.4E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 SUPERFAMILY SSF46689 19 107 2.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 Gene3D G3DSA:1.10.10.10 93 142 7.0E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 Pfam PF13011 leucine-zipper of insertion element IS481 25 105 3.2E-19 T 29-03-2018 IPR024967 DNA-binding domain, IS481-type MSG_RS16290 65c8b2338647143fddc2d58003aa1ac7 358 Pfam PF00665 Integrase core domain 154 309 6.1E-41 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS13445 add028ff0a5a47914a5d8155e9e697a3 158 SUPERFAMILY SSF54427 3 130 9.17E-23 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS13445 add028ff0a5a47914a5d8155e9e697a3 158 Gene3D G3DSA:3.10.450.50 4 154 2.7E-20 T 29-03-2018 MSG_RS13445 add028ff0a5a47914a5d8155e9e697a3 158 Pfam PF12680 SnoaL-like domain 21 109 2.3E-12 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS03350 5bfd865753f1fb073b942801959f1e94 191 Gene3D G3DSA:1.20.1290.10 37 189 1.9E-26 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS03350 5bfd865753f1fb073b942801959f1e94 191 SUPERFAMILY SSF69118 20 188 1.44E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS03350 5bfd865753f1fb073b942801959f1e94 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 120 1.6E-13 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS22345 9c1d192b2f61c8487c2756dacab2e412 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 379 1.3E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22345 9c1d192b2f61c8487c2756dacab2e412 385 Gene3D G3DSA:3.30.565.10 168 379 2.3E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22345 9c1d192b2f61c8487c2756dacab2e412 385 SUPERFAMILY SSF55874 266 379 3.27E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05180 a5f4d52a255010814513f471cb0b7b6a 516 Gene3D G3DSA:1.10.150.20 154 230 3.8E-9 T 29-03-2018 MSG_RS05180 a5f4d52a255010814513f471cb0b7b6a 516 Pfam PF00817 impB/mucB/samB family 8 140 2.2E-11 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MSG_RS05180 a5f4d52a255010814513f471cb0b7b6a 516 Gene3D G3DSA:3.30.70.270 28 88 1.0E-5 T 29-03-2018 MSG_RS05180 a5f4d52a255010814513f471cb0b7b6a 516 SUPERFAMILY SSF56672 13 223 1.6E-29 T 29-03-2018 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 Pfam PF00013 KH domain 24 79 2.8E-5 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 SMART SM00322 19 82 2.8E-9 T 29-03-2018 IPR004087 K Homology domain GO:0003676 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 SUPERFAMILY SSF52540 121 301 2.01E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 Gene3D G3DSA:3.30.1370.10 12 89 3.5E-8 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 Gene3D G3DSA:3.40.50.300 122 330 5.4E-31 T 29-03-2018 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 Pfam PF02562 PhoH-like protein 126 329 3.6E-95 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 MSG_RS16715 d5ed6fc8ef97270c38ee857cf80a3602 352 SUPERFAMILY SSF54791 22 82 6.99E-7 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MSG_RS07450 f0c7ec4955600f665f033adcdcf4889e 358 Pfam PF01497 Periplasmic binding protein 91 331 1.7E-18 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MSG_RS07450 f0c7ec4955600f665f033adcdcf4889e 358 Gene3D G3DSA:3.40.50.1980 191 352 6.2E-28 T 29-03-2018 MSG_RS07450 f0c7ec4955600f665f033adcdcf4889e 358 Gene3D G3DSA:3.40.50.1980 72 190 9.6E-24 T 29-03-2018 MSG_RS07450 f0c7ec4955600f665f033adcdcf4889e 358 SUPERFAMILY SSF53807 81 339 1.26E-45 T 29-03-2018 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 SMART SM00228 406 478 3.2E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 PRINTS PR00834 HtrA/DegQ protease family signature 200 212 9.9E-33 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 PRINTS PR00834 HtrA/DegQ protease family signature 353 370 9.9E-33 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 PRINTS PR00834 HtrA/DegQ protease family signature 436 448 9.9E-33 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 PRINTS PR00834 HtrA/DegQ protease family signature 290 314 9.9E-33 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 PRINTS PR00834 HtrA/DegQ protease family signature 331 348 9.9E-33 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 SUPERFAMILY SSF50494 164 210 1.44E-53 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS20225 adfc51817e89864464314eab5164f8af 493 SUPERFAMILY SSF50494 239 402 1.44E-53 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS20225 adfc51817e89864464314eab5164f8af 493 Gene3D G3DSA:2.40.10.10 291 407 3.4E-37 T 29-03-2018 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 Pfam PF13180 PDZ domain 407 488 8.6E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 Pfam PF13365 Trypsin-like peptidase domain 191 360 6.3E-34 T 29-03-2018 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 Gene3D G3DSA:2.40.10.10 161 290 6.0E-30 T 29-03-2018 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 SUPERFAMILY SSF50156 405 490 3.42E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS20225 adfc51817e89864464314eab5164f8af 493 Gene3D G3DSA:2.30.42.10 408 493 1.1E-16 T 29-03-2018 MSG_RS15425 096f804f279f68978b0d16882912ec0b 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 217 1.6E-11 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS15425 096f804f279f68978b0d16882912ec0b 307 Gene3D G3DSA:3.40.50.720 10 304 2.7E-28 T 29-03-2018 MSG_RS15425 096f804f279f68978b0d16882912ec0b 307 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 10 297 3.8E-99 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 MSG_RS15425 096f804f279f68978b0d16882912ec0b 307 Pfam PF08338 Domain of unknown function (DUF1731) 254 297 1.3E-14 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 MSG_RS15425 096f804f279f68978b0d16882912ec0b 307 SUPERFAMILY SSF51735 9 261 6.16E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07375 81768e52a35102b98f49efc856552588 152 SUPERFAMILY SSF52402 3 149 3.68E-28 T 29-03-2018 MSG_RS07375 81768e52a35102b98f49efc856552588 152 Gene3D G3DSA:3.40.50.620 2 152 2.3E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS07375 81768e52a35102b98f49efc856552588 152 PRINTS PR01438 Universal stress protein signature 127 149 8.7E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS07375 81768e52a35102b98f49efc856552588 152 PRINTS PR01438 Universal stress protein signature 4 22 8.7E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS07375 81768e52a35102b98f49efc856552588 152 PRINTS PR01438 Universal stress protein signature 109 121 8.7E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS07375 81768e52a35102b98f49efc856552588 152 Pfam PF00582 Universal stress protein family 4 149 3.4E-26 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS15805 6edc4c2530dc4e72adf2bb41fbff61d1 369 Gene3D G3DSA:1.10.10.10 23 100 7.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS15805 6edc4c2530dc4e72adf2bb41fbff61d1 369 Gene3D G3DSA:3.40.50.150 101 360 2.0E-25 T 29-03-2018 MSG_RS15805 6edc4c2530dc4e72adf2bb41fbff61d1 369 Pfam PF13847 Methyltransferase domain 188 344 1.8E-25 T 29-03-2018 IPR025714 Methyltransferase domain MSG_RS15805 6edc4c2530dc4e72adf2bb41fbff61d1 369 SUPERFAMILY SSF53335 177 364 5.68E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04860 c44fd80fe903b5a89f1fbae74dfa6642 214 SUPERFAMILY SSF53474 34 213 4.59E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04860 c44fd80fe903b5a89f1fbae74dfa6642 214 Gene3D G3DSA:3.40.50.1820 19 214 6.1E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04860 c44fd80fe903b5a89f1fbae74dfa6642 214 SMART SM01110 32 213 1.5E-74 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS04860 c44fd80fe903b5a89f1fbae74dfa6642 214 Pfam PF01083 Cutinase 33 212 1.3E-44 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 SUPERFAMILY SSF54373 301 406 5.23E-16 T 29-03-2018 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 SUPERFAMILY SSF51905 46 316 2.16E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 SUPERFAMILY SSF51905 394 460 2.16E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 424 439 9.7E-7 T 29-03-2018 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 48 70 9.7E-7 T 29-03-2018 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 Gene3D G3DSA:3.90.660.10 207 412 8.6E-40 T 29-03-2018 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 Pfam PF01593 Flavin containing amine oxidoreductase 56 456 5.0E-69 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS06625 a1de27518a0749fd48cf483856d0ea1b 464 Gene3D G3DSA:3.50.50.60 43 206 3.6E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS07820 738ca6ac6ca8d548825a1c20c8466883 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 100 3.6E-21 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS07820 738ca6ac6ca8d548825a1c20c8466883 170 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 142 3.5E-33 T 29-03-2018 IPR019920 F420-binding domain, putative MSG_RS07820 738ca6ac6ca8d548825a1c20c8466883 170 SUPERFAMILY SSF50475 9 148 1.66E-38 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS07820 738ca6ac6ca8d548825a1c20c8466883 170 Gene3D G3DSA:2.30.110.10 5 155 1.1E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 SUPERFAMILY SSF56645 6 217 2.23E-32 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 SUPERFAMILY SSF47203 228 363 3.38E-31 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 Gene3D G3DSA:2.40.110.10 121 212 2.6E-7 T 29-03-2018 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 359 4.0E-20 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 4.5E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 Gene3D G3DSA:1.20.140.10 213 367 1.4E-26 T 29-03-2018 MSG_RS12300 7b3b453c115fc379170922ecf2009b0a 372 Gene3D G3DSA:1.10.540.10 1 120 2.5E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 271 7.6E-44 T 29-03-2018 MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 SUPERFAMILY SSF51735 3 273 2.92E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 8.4E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 Gene3D G3DSA:3.40.50.720 47 273 2.1E-53 T 29-03-2018 MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 Gene3D G3DSA:3.40.50.720 1 44 1.1E-6 T 29-03-2018 MSG_RS12125 71e085a28406f44c4e281bae1a5afccf 273 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 272 6.5E-106 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS13170 258b2ba61778cf0394823eb8f4259177 375 SUPERFAMILY SSF51556 150 173 3.93E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS13170 258b2ba61778cf0394823eb8f4259177 375 SUPERFAMILY SSF51556 200 370 3.93E-13 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS13170 258b2ba61778cf0394823eb8f4259177 375 Pfam PF04909 Amidohydrolase 200 370 1.2E-14 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS13170 258b2ba61778cf0394823eb8f4259177 375 Gene3D G3DSA:3.20.20.140 6 375 3.8E-61 T 29-03-2018 MSG_RS17180 b47445723e8d8965d64a73c52d22cc17 419 SUPERFAMILY SSF51735 10 171 1.1E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17180 b47445723e8d8965d64a73c52d22cc17 419 Gene3D G3DSA:3.40.50.720 3 161 3.3E-21 T 29-03-2018 MSG_RS17180 b47445723e8d8965d64a73c52d22cc17 419 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 10 137 1.9E-13 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 359 527 1.1E-22 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 SMART SM00044 326 516 1.4E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 SUPERFAMILY SSF55073 353 532 6.75E-42 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 Gene3D G3DSA:3.30.70.1230 355 535 2.5E-39 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 Pfam PF00672 HAMP domain 281 327 1.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 SMART SM00304 278 330 2.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS18155 ca33effe14fd6adf0398bb426992c5df 535 SUPERFAMILY SSF158472 280 327 4.71E-6 T 29-03-2018 MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 260 32.629 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 192 4.6E-41 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 PIRSF PIRSF006493 1 304 3.2E-99 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 SMART SM00559 52 184 3.4E-48 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 Gene3D G3DSA:2.40.290.10 1 186 4.3E-38 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 262 2.7E-95 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MSG_RS20470 b33e972ed9670e1764f3f4a11b2194b2 310 SUPERFAMILY SSF100939 1 260 1.2E-57 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Gene3D G3DSA:3.30.200.20 1 97 1.7E-20 T 29-03-2018 MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Pfam PF00069 Protein kinase domain 11 265 2.3E-49 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Pfam PF03793 PASTA domain 425 486 1.6E-9 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Pfam PF03793 PASTA domain 493 554 2.2E-12 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Pfam PF03793 PASTA domain 357 419 1.4E-12 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Pfam PF03793 PASTA domain 559 621 5.0E-9 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 Gene3D G3DSA:1.10.510.10 98 295 1.0E-53 T 29-03-2018 MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SMART SM00740 420 487 1.5E-13 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SMART SM00740 353 419 2.8E-13 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SMART SM00740 555 623 7.8E-8 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SMART SM00740 488 554 5.5E-11 T 29-03-2018 IPR005543 PASTA domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SUPERFAMILY SSF56112 8 275 9.04E-78 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 SMART SM00220 11 274 1.5E-68 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS00100 f88d15a430ef5dd01fae98cd7142a5f2 623 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 8 344 36.507 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 Gene3D G3DSA:3.40.50.10210 68 325 8.1E-98 T 29-03-2018 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 SUPERFAMILY SSF52733 5 343 1.14E-110 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 Pfam PF02277 Phosphoribosyltransferase 6 342 2.9E-129 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 10 342 3.0E-122 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15375 744755ddb56f5d35750d23d5f145d442 352 Gene3D G3DSA:1.10.1610.10 2 67 6.6E-32 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS03855 d4fbb1b7c0430ade43dce29a5a058bfc 399 Gene3D G3DSA:3.40.50.2000 11 208 1.5E-24 T 29-03-2018 MSG_RS03855 d4fbb1b7c0430ade43dce29a5a058bfc 399 SUPERFAMILY SSF53756 18 379 2.01E-68 T 29-03-2018 MSG_RS03855 d4fbb1b7c0430ade43dce29a5a058bfc 399 Pfam PF00534 Glycosyl transferases group 1 215 360 2.7E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS03855 d4fbb1b7c0430ade43dce29a5a058bfc 399 Gene3D G3DSA:3.40.50.2000 209 366 2.0E-32 T 29-03-2018 MSG_RS03855 d4fbb1b7c0430ade43dce29a5a058bfc 399 Pfam PF13439 Glycosyltransferase Family 4 30 197 3.3E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS23085 556183b251644ee8212db43dd1f6f871 147 Pfam PF14016 Protein of unknown function (DUF4232) 12 142 3.7E-12 T 29-03-2018 IPR025326 Protein of unknown function DUF4232 MSG_RS19260 e22c80290a68a4f2de2c4294ba8889b1 266 Gene3D G3DSA:3.90.226.10 2 204 2.2E-63 T 29-03-2018 MSG_RS19260 e22c80290a68a4f2de2c4294ba8889b1 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 265 3.6E-61 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS19260 e22c80290a68a4f2de2c4294ba8889b1 266 SUPERFAMILY SSF52096 7 265 1.78E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS19260 e22c80290a68a4f2de2c4294ba8889b1 266 Gene3D G3DSA:1.10.12.10 206 266 5.4E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS19260 e22c80290a68a4f2de2c4294ba8889b1 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS21655 4c9e8e3558e801206f7297b97e727419 340 PIRSF PIRSF000346 1 329 4.3E-113 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS21655 4c9e8e3558e801206f7297b97e727419 340 SUPERFAMILY SSF47240 2 311 3.11E-90 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS21655 4c9e8e3558e801206f7297b97e727419 340 Pfam PF03405 Fatty acid desaturase 7 318 1.3E-89 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS21655 4c9e8e3558e801206f7297b97e727419 340 Gene3D G3DSA:1.10.620.20 1 320 1.3E-98 T 29-03-2018 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 Gene3D G3DSA:3.40.605.10 8 277 3.7E-96 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 SUPERFAMILY SSF53720 14 499 9.42E-161 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 3.9E-161 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS03320 97114cb3a87ccb31c855624d78503270 507 Gene3D G3DSA:3.40.309.10 278 481 1.8E-63 T 29-03-2018 MSG_RS22475 73aafc6cb384dc7eea8a6daa4ef28993 389 SUPERFAMILY SSF53901 3 236 4.57E-22 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22475 73aafc6cb384dc7eea8a6daa4ef28993 389 PIRSF PIRSF000429 1 342 3.9E-21 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22475 73aafc6cb384dc7eea8a6daa4ef28993 389 SUPERFAMILY SSF53901 264 380 1.4E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22475 73aafc6cb384dc7eea8a6daa4ef28993 389 Gene3D G3DSA:3.40.47.10 12 132 6.1E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22475 73aafc6cb384dc7eea8a6daa4ef28993 389 Gene3D G3DSA:3.40.47.10 150 387 2.0E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 Pfam PF01029 NusB family 21 142 7.0E-26 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 250 264 4.3E-23 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 446 463 4.3E-23 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 283 293 4.3E-23 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 346 358 4.3E-23 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 396 412 4.3E-23 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 Pfam PF01189 16S rRNA methyltransferase RsmB/F 278 462 1.4E-57 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 SUPERFAMILY SSF48013 21 176 8.5E-33 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 345 356 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 SUPERFAMILY SSF53335 165 463 1.34E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 Gene3D G3DSA:1.10.940.10 17 160 1.3E-29 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MSG_RS10330 7a2d4246c3151d555bc02f3995a2dee7 465 Gene3D G3DSA:3.40.50.150 259 465 4.2E-48 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 Pfam PF01494 FAD binding domain 7 346 9.6E-62 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 SUPERFAMILY SSF51905 268 381 4.31E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 SUPERFAMILY SSF51905 7 179 4.31E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.7E-35 T 29-03-2018 MSG_RS17610 b11912ceb17db3a444b1be14a03e155d 515 Gene3D G3DSA:3.50.50.60 2 376 2.5E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00130 7d64eed925ce9f302cf0b759eeea73c6 497 Pfam PF00498 FHA domain 426 488 3.3E-16 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS00130 7d64eed925ce9f302cf0b759eeea73c6 497 Gene3D G3DSA:2.60.200.20 297 496 2.5E-24 T 29-03-2018 MSG_RS00130 7d64eed925ce9f302cf0b759eeea73c6 497 Pfam PF12401 Protein of unknown function (DUF2662) 10 121 1.5E-34 T 29-03-2018 IPR022128 Domain of unknown function DUF3662 MSG_RS00130 7d64eed925ce9f302cf0b759eeea73c6 497 SUPERFAMILY SSF49879 401 496 1.03E-27 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS00130 7d64eed925ce9f302cf0b759eeea73c6 497 SMART SM00240 424 474 4.4E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 350 361 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 341 350 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 188 210 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 274 285 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 150 165 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 87 98 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 133 149 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00359 B-class P450 signature 291 318 1.6E-30 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 Gene3D G3DSA:1.10.630.10 2 399 5.0E-58 T 29-03-2018 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 Pfam PF00067 Cytochrome P450 203 371 4.5E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00385 P450 superfamily signature 274 285 4.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00385 P450 superfamily signature 239 256 4.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00385 P450 superfamily signature 341 350 4.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 PRINTS PR00385 P450 superfamily signature 350 361 4.3E-7 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS12395 be427f8ac47b302b1d2f57322d58a9e3 400 SUPERFAMILY SSF48264 13 398 2.62E-85 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 Gene3D G3DSA:1.10.540.10 1 118 1.1E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 Gene3D G3DSA:1.20.140.10 177 316 7.0E-30 T 29-03-2018 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 101 2.5E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 SUPERFAMILY SSF56645 1 128 2.54E-14 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 183 301 7.7E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22595 b35f9e1c722572515b975f3dbc14b6b2 316 SUPERFAMILY SSF47203 180 308 2.42E-33 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 SUPERFAMILY SSF46785 4 77 3.68E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.8E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 Gene3D G3DSA:1.10.10.10 1 74 1.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 SUPERFAMILY SSF64288 62 243 2.2E-25 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 Gene3D G3DSA:3.40.1410.10 79 245 2.3E-23 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 Pfam PF07702 UTRA domain 108 236 9.3E-14 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.2E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 SMART SM00866 96 236 2.7E-15 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MSG_RS01115 427abfd118cbb3d13f5f807308dc2bd1 246 SMART SM00345 14 73 3.9E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS16210 1d0b283b606507e106af286171539a56 235 SUPERFAMILY SSF52317 45 204 1.48E-15 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS16210 1d0b283b606507e106af286171539a56 235 Pfam PF03575 Peptidase family S51 52 204 1.7E-12 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 MSG_RS16210 1d0b283b606507e106af286171539a56 235 Gene3D G3DSA:3.40.50.880 22 229 2.0E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 232 438 2.3E-69 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 98 233 1.1E-40 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 111 130 3.9E-26 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 276 298 3.9E-26 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 333 347 3.9E-26 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 348 362 3.9E-26 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 416 429 3.9E-26 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 SUPERFAMILY SSF56601 84 456 1.29E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 Gene3D G3DSA:3.40.710.10 74 458 3.9E-28 T 29-03-2018 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 240 454 8.8E-74 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22920 68c42afaae611a2507bd0f3a9ae54a43 461 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 73 239 7.7E-50 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MSG_RS22185 5897785c51b795c4d9dfd7570997853d 382 Pfam PF03595 Voltage-dependent anion channel 22 355 6.7E-71 T 29-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 MSG_RS15630 62fd4bd4535283f6c727fb7346e78dc5 119 Gene3D G3DSA:3.30.70.100 13 86 5.2E-18 T 29-03-2018 MSG_RS15630 62fd4bd4535283f6c727fb7346e78dc5 119 SUPERFAMILY SSF55008 14 84 2.36E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS15630 62fd4bd4535283f6c727fb7346e78dc5 119 ProSitePatterns PS01047 Heavy-metal-associated domain. 23 51 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MSG_RS15630 62fd4bd4535283f6c727fb7346e78dc5 119 Pfam PF00403 Heavy-metal-associated domain 23 78 2.3E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS08715 17dd4808a0515fff026113a4b3bcc3c6 269 Gene3D G3DSA:3.10.129.10 7 109 8.0E-10 T 29-03-2018 MSG_RS08715 17dd4808a0515fff026113a4b3bcc3c6 269 Pfam PF13622 Thioesterase-like superfamily 28 253 1.0E-21 T 29-03-2018 MSG_RS08715 17dd4808a0515fff026113a4b3bcc3c6 269 SUPERFAMILY SSF54637 10 106 1.01E-7 T 29-03-2018 IPR029069 HotDog domain MSG_RS23175 e4af8409ac012240222f78b32104d283 319 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 52 233 3.6E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MSG_RS23175 e4af8409ac012240222f78b32104d283 319 Gene3D G3DSA:3.60.21.10 43 282 5.8E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS23175 e4af8409ac012240222f78b32104d283 319 SUPERFAMILY SSF56300 47 289 9.34E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS09500 d1b9053cb337e3a5f9b3bce8da08d2c3 221 Pfam PF09335 SNARE associated Golgi protein 32 161 3.4E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Gene3D G3DSA:3.40.50.300 1065 1252 4.9E-7 T 29-03-2018 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Pfam PF01580 FtsK/SpoIIIE family 1089 1135 1.7E-5 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Pfam PF01580 FtsK/SpoIIIE family 793 1037 1.0E-61 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Pfam PF01580 FtsK/SpoIIIE family 442 639 1.5E-17 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SUPERFAMILY SSF52540 434 706 1.84E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SUPERFAMILY SSF52540 826 1001 2.25E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Gene3D G3DSA:3.40.50.300 754 1001 1.0E-7 T 29-03-2018 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 Gene3D G3DSA:3.40.50.300 374 686 1.0E-21 T 29-03-2018 MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SMART SM00382 1095 1268 0.0074 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SMART SM00382 825 995 0.3 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SMART SM00382 471 661 1.2 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 709 8.1E-224 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 SUPERFAMILY SSF52540 1082 1259 1.7E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11605 56008d01242688c1788f91e30cbb5d4b 1319 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 757 1305 6.1E-161 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS18095 6b64e77fa7b2cc568a2838ee1101bc90 193 Pfam PF09438 Domain of unknown function (DUF2017) 11 189 3.3E-57 T 29-03-2018 IPR018561 Domain of unknown function DUF2017 MSG_RS21260 043b05a7b80f035fa54e9796598089e2 97 Gene3D G3DSA:3.30.70.100 2 97 3.6E-24 T 29-03-2018 MSG_RS21260 043b05a7b80f035fa54e9796598089e2 97 SUPERFAMILY SSF54909 6 96 3.64E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS21260 043b05a7b80f035fa54e9796598089e2 97 Pfam PF07045 Domain of unknown function (DUF1330) 6 96 1.4E-28 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 MSG_RS12680 0bc1c0c4ce3094669f4cfa491af46ac6 94 Gene3D G3DSA:1.10.287.1060 1 94 6.1E-13 T 29-03-2018 MSG_RS12680 0bc1c0c4ce3094669f4cfa491af46ac6 94 SUPERFAMILY SSF140453 2 93 9.02E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS12680 0bc1c0c4ce3094669f4cfa491af46ac6 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 5.5E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS19775 0bc1c0c4ce3094669f4cfa491af46ac6 94 Gene3D G3DSA:1.10.287.1060 1 94 6.1E-13 T 29-03-2018 MSG_RS19775 0bc1c0c4ce3094669f4cfa491af46ac6 94 SUPERFAMILY SSF140453 2 93 9.02E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS19775 0bc1c0c4ce3094669f4cfa491af46ac6 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 5.5E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS15325 25b321951c95e7f9a5fa3c4601424f9a 320 PRINTS PR01217 Proline rich extensin signature 188 200 4.6E-10 T 29-03-2018 MSG_RS15325 25b321951c95e7f9a5fa3c4601424f9a 320 PRINTS PR01217 Proline rich extensin signature 147 159 4.6E-10 T 29-03-2018 MSG_RS15325 25b321951c95e7f9a5fa3c4601424f9a 320 PRINTS PR01217 Proline rich extensin signature 167 183 4.6E-10 T 29-03-2018 MSG_RS15325 25b321951c95e7f9a5fa3c4601424f9a 320 PRINTS PR01217 Proline rich extensin signature 203 224 4.6E-10 T 29-03-2018 MSG_RS15325 25b321951c95e7f9a5fa3c4601424f9a 320 Pfam PF05423 Mycobacterium membrane protein 222 307 3.9E-7 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS08990 fc4d9da74bc2b90e351c2426ec558a65 351 Pfam PF13830 Domain of unknown function (DUF4192) 13 320 9.8E-84 T 29-03-2018 IPR025447 Protein of unknown function DUF4192 MSG_RS21210 5afad5ea61e9e0a1be482fdb48cc41a3 288 Gene3D G3DSA:3.40.50.1820 5 288 1.7E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21210 5afad5ea61e9e0a1be482fdb48cc41a3 288 SUPERFAMILY SSF53474 3 246 6.12E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13520 7cfd68ec5cff9caee7c0e6a12296d171 214 Gene3D G3DSA:3.20.80.10 131 214 1.4E-4 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MSG_RS13520 7cfd68ec5cff9caee7c0e6a12296d171 214 SUPERFAMILY SSF55136 20 207 3.14E-50 T 29-03-2018 MSG_RS13520 7cfd68ec5cff9caee7c0e6a12296d171 214 Pfam PF04832 SOUL heme-binding protein 25 206 1.4E-43 T 29-03-2018 IPR006917 SOUL haem-binding protein MSG_RS09150 23daaf942dc96602a8724203cbbc0dca 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 264 1.3E-40 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS09150 23daaf942dc96602a8724203cbbc0dca 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS09150 23daaf942dc96602a8724203cbbc0dca 268 Gene3D G3DSA:3.90.226.10 9 220 2.4E-47 T 29-03-2018 MSG_RS09150 23daaf942dc96602a8724203cbbc0dca 268 SUPERFAMILY SSF52096 17 262 3.95E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS09150 23daaf942dc96602a8724203cbbc0dca 268 Gene3D G3DSA:1.10.12.10 221 268 1.3E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 Pfam PF07690 Major Facilitator Superfamily 264 427 4.8E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 SUPERFAMILY SSF103473 13 441 5.23E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 Gene3D G3DSA:1.20.1250.20 230 443 1.6E-23 T 29-03-2018 MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 Gene3D G3DSA:1.20.1250.20 14 229 3.9E-24 T 29-03-2018 MSG_RS20585 13e906f635940f7a74155ea1c9b52cb3 460 Pfam PF00083 Sugar (and other) transporter 22 230 1.1E-22 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MSG_RS10815 69c06f931456f67560597b7e15ce20a9 404 Gene3D G3DSA:3.90.550.10 2 258 1.0E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS10815 69c06f931456f67560597b7e15ce20a9 404 Pfam PF00535 Glycosyl transferase family 2 7 101 2.3E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS10815 69c06f931456f67560597b7e15ce20a9 404 SUPERFAMILY SSF53448 4 147 2.01E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS10815 69c06f931456f67560597b7e15ce20a9 404 SUPERFAMILY SSF53448 175 233 2.01E-31 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS14135 47bf29a5385f2383b6987b72f3aa9ff7 164 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 148 5.8E-27 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS14135 47bf29a5385f2383b6987b72f3aa9ff7 164 SUPERFAMILY SSF53163 5 154 3.01E-27 T 29-03-2018 IPR023430 Peptidase HybD-like domain MSG_RS14135 47bf29a5385f2383b6987b72f3aa9ff7 164 Gene3D G3DSA:3.40.50.1450 2 160 6.2E-30 T 29-03-2018 IPR023430 Peptidase HybD-like domain MSG_RS14135 47bf29a5385f2383b6987b72f3aa9ff7 164 Pfam PF01750 Hydrogenase maturation protease 46 146 1.2E-9 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MSG_RS02375 e9e86e7faaa80bd39076ee7a14a90d02 102 Gene3D G3DSA:1.10.287.1060 1 99 4.7E-5 T 29-03-2018 MSG_RS02375 e9e86e7faaa80bd39076ee7a14a90d02 102 Pfam PF00934 PE family 3 92 7.2E-22 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS02375 e9e86e7faaa80bd39076ee7a14a90d02 102 SUPERFAMILY SSF140459 7 73 3.14E-13 T 29-03-2018 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 37 402 5.0E-156 T 29-03-2018 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 404 132.292 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 SUPERFAMILY SSF56266 18 400 2.22E-120 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 404 3.0E-108 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 Gene3D G3DSA:3.60.70.12 10 279 1.9E-93 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS11500 6dd55d1bffbd455020b291b7533e8d3e 404 Pfam PF01960 ArgJ family 23 404 1.4E-125 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 Gene3D G3DSA:3.40.50.300 223 466 1.4E-36 T 29-03-2018 MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 SUPERFAMILY SSF52540 234 452 1.33E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 SUPERFAMILY SSF49879 23 119 1.31E-5 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 Pfam PF00005 ABC transporter 244 389 3.0E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 Gene3D G3DSA:2.60.200.20 10 106 4.7E-4 T 29-03-2018 MSG_RS16465 637580d6a65e5315c1eecfe9a6f8a3e5 778 Pfam PF01061 ABC-2 type transporter 508 722 2.0E-11 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS23375 ce4d594dd7dae122b4caa50fe36a1148 177 PRINTS PR01217 Proline rich extensin signature 127 143 2.1E-10 T 29-03-2018 MSG_RS23375 ce4d594dd7dae122b4caa50fe36a1148 177 PRINTS PR01217 Proline rich extensin signature 44 56 2.1E-10 T 29-03-2018 MSG_RS23375 ce4d594dd7dae122b4caa50fe36a1148 177 PRINTS PR01217 Proline rich extensin signature 1 13 2.1E-10 T 29-03-2018 MSG_RS23375 ce4d594dd7dae122b4caa50fe36a1148 177 PRINTS PR01217 Proline rich extensin signature 159 177 2.1E-10 T 29-03-2018 MSG_RS23375 ce4d594dd7dae122b4caa50fe36a1148 177 PRINTS PR01217 Proline rich extensin signature 18 34 2.1E-10 T 29-03-2018 MSG_RS13275 63e728f604199f725abdaed53f46ed0d 262 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 24 207 6.5E-13 T 29-03-2018 MSG_RS13275 63e728f604199f725abdaed53f46ed0d 262 Gene3D G3DSA:3.40.50.1000 22 260 6.4E-13 T 29-03-2018 IPR023214 HAD-like domain MSG_RS13275 63e728f604199f725abdaed53f46ed0d 262 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 24 220 8.3E-43 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MSG_RS13275 63e728f604199f725abdaed53f46ed0d 262 Pfam PF12710 haloacid dehalogenase-like hydrolase 24 205 1.1E-25 T 29-03-2018 MSG_RS13275 63e728f604199f725abdaed53f46ed0d 262 SUPERFAMILY SSF56784 24 228 4.35E-22 T 29-03-2018 IPR023214 HAD-like domain MSG_RS09080 0617ae0749e47fa68f69557609c804e0 122 PIRSF PIRSF006910 1 122 1.1E-66 T 29-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted MSG_RS09080 0617ae0749e47fa68f69557609c804e0 122 Gene3D G3DSA:2.40.50.140 34 122 4.9E-8 T 29-03-2018 MSG_RS03170 39ae20cf04545edc21633caa9ce191fc 449 Gene3D G3DSA:1.20.1250.20 1 186 2.0E-29 T 29-03-2018 MSG_RS03170 39ae20cf04545edc21633caa9ce191fc 449 SUPERFAMILY SSF103473 2 183 1.57E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS03170 39ae20cf04545edc21633caa9ce191fc 449 SUPERFAMILY SSF103473 234 437 1.57E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS03170 39ae20cf04545edc21633caa9ce191fc 449 Pfam PF07690 Major Facilitator Superfamily 6 392 2.4E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS03170 39ae20cf04545edc21633caa9ce191fc 449 Gene3D G3DSA:1.20.1250.20 237 440 8.4E-15 T 29-03-2018 MSG_RS23055 a340c7b837f9d2c7b143be33e85a5695 250 Gene3D G3DSA:1.10.3290.10 17 250 1.1E-9 T 29-03-2018 IPR003812 Fido domain MSG_RS11675 c56df9a722adf75b827ed5a1c1471e56 118 Pfam PF05305 Protein of unknown function (DUF732) 16 108 4.1E-21 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS11675 c56df9a722adf75b827ed5a1c1471e56 118 Gene3D G3DSA:3.40.1190.20 11 117 4.3E-5 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS09765 6d4b7a54507451cd577bbb0f2e32379f 341 Pfam PF04055 Radical SAM superfamily 69 240 1.2E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS09765 6d4b7a54507451cd577bbb0f2e32379f 341 SUPERFAMILY SSF102114 63 273 6.93E-11 T 29-03-2018 MSG_RS09765 6d4b7a54507451cd577bbb0f2e32379f 341 SMART SM00729 62 288 0.0018 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS09765 6d4b7a54507451cd577bbb0f2e32379f 341 Gene3D G3DSA:3.20.20.70 44 320 6.7E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS17740 54de2f46466fb76cfe8c03c9a4eb0070 311 Gene3D G3DSA:1.20.140.10 156 276 5.9E-17 T 29-03-2018 MSG_RS17740 54de2f46466fb76cfe8c03c9a4eb0070 311 SUPERFAMILY SSF47203 157 279 2.58E-20 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17740 54de2f46466fb76cfe8c03c9a4eb0070 311 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 165 275 7.0E-14 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 349 44.607 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 348 6.1E-123 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 Gene3D G3DSA:3.20.20.210 1 349 2.1E-98 T 29-03-2018 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 348 1.5E-126 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 SUPERFAMILY SSF51726 9 348 2.09E-98 T 29-03-2018 MSG_RS09155 631ab3f256efa9b09ffa0a38cd9b7ff2 349 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MSG_RS20435 eda3b91d763793dfc615f05147911d97 306 Pfam PF04072 Leucine carboxyl methyltransferase 19 201 7.4E-63 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS20435 eda3b91d763793dfc615f05147911d97 306 SUPERFAMILY SSF53335 15 283 2.74E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS20435 eda3b91d763793dfc615f05147911d97 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 276 2.9E-77 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS20435 eda3b91d763793dfc615f05147911d97 306 Gene3D G3DSA:3.40.50.150 2 291 9.3E-53 T 29-03-2018 MSG_RS09585 fd3929969118ad563a24871736755059 221 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 93 1.7E-9 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS09585 fd3929969118ad563a24871736755059 221 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 SUPERFAMILY SSF52540 160 238 2.21E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 SUPERFAMILY SSF52540 483 704 2.21E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 SUPERFAMILY SSF52540 342 394 2.21E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 Gene3D G3DSA:3.40.50.300 653 721 1.1E-9 T 29-03-2018 MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 Pfam PF01443 Viral (Superfamily 1) RNA helicase 512 700 1.6E-4 T 29-03-2018 IPR027351 (+) RNA virus helicase core domain GO:0005524 MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 182 230 9.7E-5 T 29-03-2018 IPR018647 Domain of unknown function DUF2075 MSG_RS09760 d9e4e642081159fadbd9e71799a322f9 724 Gene3D G3DSA:3.40.50.300 165 566 5.4E-33 T 29-03-2018 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 Gene3D G3DSA:3.90.380.10 154 437 1.5E-52 T 29-03-2018 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 Pfam PF00355 Rieske [2Fe-2S] domain 50 133 1.5E-15 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 184 430 4.8E-26 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 6.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 106 126 6.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 6.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 6.6E-21 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 SUPERFAMILY SSF55961 316 432 1.33E-29 T 29-03-2018 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 SUPERFAMILY SSF55961 163 277 1.33E-29 T 29-03-2018 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 SUPERFAMILY SSF50022 20 163 4.84E-41 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS00765 1d63bd91c58dcaa3b0be036c9d1b860b 445 Gene3D G3DSA:2.102.10.10 47 153 1.3E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 SUPERFAMILY SSF51905 161 298 1.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 SUPERFAMILY SSF51905 9 133 1.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 SUPERFAMILY SSF51905 423 485 1.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 455 2.1E-5 T 29-03-2018 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 2.1E-5 T 29-03-2018 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 SUPERFAMILY SSF56425 296 424 2.04E-24 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 Gene3D G3DSA:3.50.50.60 16 482 5.2E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12780 464e56281922a655f5bd86791cffe26e 490 Pfam PF00890 FAD binding domain 22 452 1.1E-50 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS01335 eef274c340df27eb54831b64eb098f70 370 SUPERFAMILY SSF160935 232 348 2.75E-6 T 29-03-2018 MSG_RS01335 eef274c340df27eb54831b64eb098f70 370 Gene3D G3DSA:2.60.120.600 195 367 3.0E-10 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS01335 eef274c340df27eb54831b64eb098f70 370 Gene3D G3DSA:2.60.120.600 72 179 2.5E-5 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS01335 eef274c340df27eb54831b64eb098f70 370 Pfam PF06742 Protein of unknown function (DUF1214) 271 344 0.0074 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 SUPERFAMILY SSF56322 71 406 1.57E-94 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 PRINTS PR00095 Anthranilate synthase component I signature 341 355 7.8E-12 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 PRINTS PR00095 Anthranilate synthase component I signature 356 370 7.8E-12 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 PRINTS PR00095 Anthranilate synthase component I signature 261 274 7.8E-12 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 PRINTS PR00095 Anthranilate synthase component I signature 247 260 7.8E-12 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 Pfam PF00425 chorismate binding enzyme 153 400 6.6E-71 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 Gene3D G3DSA:3.60.120.10 37 407 1.5E-96 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS20080 cc5084d68e6d6853bc23b7a63e11e0d7 419 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 78 404 8.6E-112 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 MSG_RS19070 df144e5adb2769b7dd837b14940a1ff9 787 Pfam PF13520 Amino acid permease 70 456 1.0E-22 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS19070 df144e5adb2769b7dd837b14940a1ff9 787 Gene3D G3DSA:2.40.50.140 682 778 4.2E-7 T 29-03-2018 MSG_RS19070 df144e5adb2769b7dd837b14940a1ff9 787 SUPERFAMILY SSF50249 685 757 3.0E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 SUPERFAMILY SSF51735 10 279 6.71E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 Gene3D G3DSA:3.40.50.720 2 280 4.9E-56 T 29-03-2018 MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 Pfam PF00106 short chain dehydrogenase 14 203 6.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 3.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07320 e726621dad16c5c7b4cd26e410e0931c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 Gene3D G3DSA:3.40.50.1820 5 296 3.3E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 239 255 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 43 61 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 107 120 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 121 134 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 63 78 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 PRINTS PR00412 Epoxide hydrolase signature 272 294 2.2E-22 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 SUPERFAMILY SSF53474 13 296 1.28E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01435 dacbfccfd41fd1715bbc52e12c1a4312 297 Pfam PF00561 alpha/beta hydrolase fold 37 146 6.6E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00910 db090e972717f273920dd720626334ef 186 Gene3D G3DSA:2.30.110.10 12 154 1.3E-14 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS00910 db090e972717f273920dd720626334ef 186 SUPERFAMILY SSF50475 14 149 3.18E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS00910 db090e972717f273920dd720626334ef 186 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 22 104 6.5E-5 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS16600 95ade3c26212cec940e4981f3cdbf2ae 190 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 178 32.969 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 MSG_RS16600 95ade3c26212cec940e4981f3cdbf2ae 190 Gene3D G3DSA:2.60.120.10 2 163 5.8E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS16600 95ade3c26212cec940e4981f3cdbf2ae 190 SUPERFAMILY SSF51182 6 184 7.72E-29 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS16600 95ade3c26212cec940e4981f3cdbf2ae 190 Pfam PF03079 ARD/ARD' family 95 170 2.6E-25 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 Pfam PF00692 dUTPase 19 153 2.9E-28 T 29-03-2018 IPR029054 dUTPase-like MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 7 154 30.354 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 Gene3D G3DSA:2.70.40.10 113 153 3.9E-10 T 29-03-2018 MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 153 8.3E-49 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 Gene3D G3DSA:2.70.40.10 1 112 7.7E-45 T 29-03-2018 MSG_RS09065 559786198afee70a6159dc3d4a7a5246 158 SUPERFAMILY SSF51283 4 153 8.24E-45 T 29-03-2018 IPR029054 dUTPase-like MSG_RS02455 ba379d7d8eaa42e2bec80cea9f26dede 213 Gene3D G3DSA:1.20.144.10 12 213 2.6E-20 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02455 ba379d7d8eaa42e2bec80cea9f26dede 213 SUPERFAMILY SSF48317 15 210 5.49E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02455 ba379d7d8eaa42e2bec80cea9f26dede 213 SMART SM00014 90 200 4.7E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02455 ba379d7d8eaa42e2bec80cea9f26dede 213 Pfam PF01569 PAP2 superfamily 95 203 1.2E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS09840 ce03ea635e0217d211669b63efd96725 265 Pfam PF13649 Methyltransferase domain 82 174 5.7E-14 T 29-03-2018 MSG_RS09840 ce03ea635e0217d211669b63efd96725 265 Gene3D G3DSA:3.40.50.150 9 251 6.4E-21 T 29-03-2018 MSG_RS09840 ce03ea635e0217d211669b63efd96725 265 SUPERFAMILY SSF53335 51 236 1.69E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07600 bc0ba566214975a0182ca71fbbe2e6e2 379 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 257 269 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS07600 bc0ba566214975a0182ca71fbbe2e6e2 379 SUPERFAMILY SSF48576 68 377 3.7E-63 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS07600 bc0ba566214975a0182ca71fbbe2e6e2 379 Gene3D G3DSA:1.10.600.10 35 379 5.8E-72 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS07600 bc0ba566214975a0182ca71fbbe2e6e2 379 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 113 127 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS07600 bc0ba566214975a0182ca71fbbe2e6e2 379 Pfam PF00348 Polyprenyl synthetase 68 324 6.0E-45 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MSG_RS05545 68c6c3e6cc2a33aeb78a2bf90bbe914e 300 Pfam PF04185 Phosphoesterase family 72 283 3.5E-34 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 MSG_RS05545 68c6c3e6cc2a33aeb78a2bf90bbe914e 300 Gene3D G3DSA:3.40.720.10 162 287 1.6E-7 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS05545 68c6c3e6cc2a33aeb78a2bf90bbe914e 300 Gene3D G3DSA:3.40.720.10 43 161 5.4E-4 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS05545 68c6c3e6cc2a33aeb78a2bf90bbe914e 300 SUPERFAMILY SSF53649 183 284 7.19E-9 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS05545 68c6c3e6cc2a33aeb78a2bf90bbe914e 300 SUPERFAMILY SSF53649 71 148 7.19E-9 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS03500 d45667bb6a6db24e0845fffa73f354c4 338 SUPERFAMILY SSF53067 2 125 8.55E-31 T 29-03-2018 MSG_RS03500 d45667bb6a6db24e0845fffa73f354c4 338 Gene3D G3DSA:3.30.420.40 1 124 8.4E-36 T 29-03-2018 MSG_RS03500 d45667bb6a6db24e0845fffa73f354c4 338 SUPERFAMILY SSF53067 130 305 2.65E-35 T 29-03-2018 MSG_RS03500 d45667bb6a6db24e0845fffa73f354c4 338 Pfam PF02541 Ppx/GppA phosphatase family 17 307 1.4E-90 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MSG_RS03500 d45667bb6a6db24e0845fffa73f354c4 338 Gene3D G3DSA:3.30.420.150 127 310 2.7E-38 T 29-03-2018 MSG_RS20020 e2e09f3c641304831c6b92e1d134bf2b 216 SUPERFAMILY SSF53335 55 197 2.74E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS20020 e2e09f3c641304831c6b92e1d134bf2b 216 Gene3D G3DSA:3.40.50.150 41 210 1.0E-8 T 29-03-2018 MSG_RS20020 e2e09f3c641304831c6b92e1d134bf2b 216 Pfam PF13578 Methyltransferase domain 62 177 2.0E-8 T 29-03-2018 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 Gene3D G3DSA:4.10.640.10 1 81 1.1E-25 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 Pfam PF01084 Ribosomal protein S18 28 76 6.9E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 29 52 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 SUPERFAMILY SSF46911 9 79 1.57E-23 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 PRINTS PR00974 Ribosomal protein S18 family signature 68 78 2.9E-13 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 PRINTS PR00974 Ribosomal protein S18 family signature 54 68 2.9E-13 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 PRINTS PR00974 Ribosomal protein S18 family signature 46 53 2.9E-13 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 PRINTS PR00974 Ribosomal protein S18 family signature 36 46 2.9E-13 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 29 78 1.0E-17 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 15 79 3.8E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01045 ef81215f741c6c017798292de62b408c 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 81 18.266 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS22175 d9a008bbecd0fea653a72349df9ebc9e 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 189 3.7E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS22175 d9a008bbecd0fea653a72349df9ebc9e 196 Gene3D G3DSA:1.10.357.10 71 196 9.2E-16 T 29-03-2018 MSG_RS22175 d9a008bbecd0fea653a72349df9ebc9e 196 SUPERFAMILY SSF48498 81 194 1.09E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS22175 d9a008bbecd0fea653a72349df9ebc9e 196 Gene3D G3DSA:1.10.10.60 16 70 4.5E-7 T 29-03-2018 MSG_RS22175 d9a008bbecd0fea653a72349df9ebc9e 196 SUPERFAMILY SSF46689 16 79 2.57E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS13200 70d130f530d8555bb5216dcf128c0814 145 Pfam PF06737 Transglycosylase-like domain 41 113 5.0E-32 T 29-03-2018 IPR010618 Transglycosylase-like MSG_RS13200 70d130f530d8555bb5216dcf128c0814 145 Gene3D G3DSA:1.10.530.10 15 120 6.0E-31 T 29-03-2018 MSG_RS13200 70d130f530d8555bb5216dcf128c0814 145 SUPERFAMILY SSF53955 42 119 5.63E-30 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 Gene3D G3DSA:3.50.50.60 288 343 1.3E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 SUPERFAMILY SSF51971 286 339 1.53E-27 T 29-03-2018 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 SUPERFAMILY SSF51971 15 221 1.53E-27 T 29-03-2018 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 SUPERFAMILY SSF54373 208 300 7.72E-16 T 29-03-2018 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 Gene3D G3DSA:3.40.50.720 13 114 4.7E-6 T 29-03-2018 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 Gene3D G3DSA:3.30.9.10 115 287 1.6E-25 T 29-03-2018 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 Pfam PF01266 FAD dependent oxidoreductase 15 336 6.7E-50 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS03020 692ce1c7a59b4790431b103c2ca0693a 346 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 17 339 1.1E-101 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 3.3E-19 T 29-03-2018 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 3.3E-19 T 29-03-2018 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 3.3E-19 T 29-03-2018 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 3.3E-19 T 29-03-2018 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 Pfam PF01494 FAD binding domain 11 327 5.7E-54 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 Gene3D G3DSA:3.50.50.60 2 396 4.0E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 SUPERFAMILY SSF51905 13 182 1.26E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16900 ddde0743b07655becbda755c1af581ce 410 SUPERFAMILY SSF51905 274 359 1.26E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16275 2d0d7a76ceee26eef57591bd9365514b 351 SUPERFAMILY SSF53474 70 340 5.0E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16275 2d0d7a76ceee26eef57591bd9365514b 351 Pfam PF07859 alpha/beta hydrolase fold 109 323 3.8E-33 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS16275 2d0d7a76ceee26eef57591bd9365514b 351 Gene3D G3DSA:3.40.50.1820 3 349 4.6E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 Gene3D G3DSA:1.10.10.10 1 103 2.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 52 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 SMART SM00418 20 98 6.3E-32 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 SUPERFAMILY SSF46785 11 92 2.01E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21635 065191a84df3ca8f09c4e24b18ff5bd4 135 Pfam PF01022 Bacterial regulatory protein, arsR family 27 72 2.6E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PIRSF PIRSF006356 2 403 1.5E-142 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 Hamap MF_00242 Arginine deiminase [arcA]. 3 403 41.474 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 Pfam PF02274 Amidinotransferase 20 400 3.0E-101 T 29-03-2018 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 TIGRFAM TIGR01078 arcA: arginine deiminase 8 401 1.1E-155 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 Gene3D G3DSA:3.75.10.10 5 401 4.8E-93 T 29-03-2018 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 155 173 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 339 356 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 183 198 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 382 400 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 PRINTS PR01466 Bacterial arginine deiminase signature 359 373 5.5E-47 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MSG_RS20095 b0c99775b7689f7d0a722ab93602c46b 403 SUPERFAMILY SSF55909 7 402 1.71E-114 T 29-03-2018 MSG_RS13585 95deab6e5074a086b3745b63c3d5cf27 358 SUPERFAMILY SSF48208 21 328 8.84E-42 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS13585 95deab6e5074a086b3745b63c3d5cf27 358 Gene3D G3DSA:1.50.10.20 16 329 7.8E-27 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 SUPERFAMILY SSF53067 160 343 3.15E-28 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 PRINTS PR01217 Proline rich extensin signature 505 522 2.7E-10 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 PRINTS PR01217 Proline rich extensin signature 461 482 2.7E-10 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 PRINTS PR01217 Proline rich extensin signature 523 548 2.7E-10 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 PRINTS PR01217 Proline rich extensin signature 488 504 2.7E-10 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 Gene3D G3DSA:3.30.420.40 4 377 6.1E-27 T 29-03-2018 MSG_RS02480 93c9b7ee5c0f42197e5efd134c7418d6 649 Pfam PF00012 Hsp70 protein 73 342 4.7E-18 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS11000 d4e7ff9b464cec4c6463caa8f877c89f 281 Gene3D G3DSA:3.40.50.150 8 218 6.5E-26 T 29-03-2018 MSG_RS11000 d4e7ff9b464cec4c6463caa8f877c89f 281 Pfam PF04072 Leucine carboxyl methyltransferase 28 177 4.3E-13 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS11000 d4e7ff9b464cec4c6463caa8f877c89f 281 PIRSF PIRSF028177 7 281 5.5E-53 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MSG_RS11000 d4e7ff9b464cec4c6463caa8f877c89f 281 SUPERFAMILY SSF53335 17 246 5.55E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 Pfam PF01494 FAD binding domain 5 344 1.7E-78 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 2.9E-34 T 29-03-2018 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.9E-34 T 29-03-2018 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.9E-34 T 29-03-2018 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 2.9E-34 T 29-03-2018 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.9E-34 T 29-03-2018 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 Gene3D G3DSA:3.50.50.60 1 390 7.0E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 SUPERFAMILY SSF51905 5 171 1.62E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00550 ab4fc6c3232540f25f28040a85d27fe7 502 SUPERFAMILY SSF51905 275 389 1.62E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 Gene3D G3DSA:3.30.1120.10 478 567 2.5E-7 T 29-03-2018 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 SUPERFAMILY SSF53649 473 564 9.16E-61 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 SUPERFAMILY SSF53649 3 125 9.16E-61 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 SUPERFAMILY SSF53649 155 437 9.16E-61 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 Gene3D G3DSA:3.40.720.10 1 423 1.3E-51 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MSG_RS16440 5be8eb40c165aed4b1f2b3dc08c0dab1 597 Pfam PF00884 Sulfatase 5 389 3.8E-52 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MSG_RS13960 407d7337e227226515d9bdf2db7b65a3 328 SUPERFAMILY SSF55469 7 87 8.38E-10 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13960 407d7337e227226515d9bdf2db7b65a3 328 Gene3D G3DSA:3.40.109.10 117 326 9.8E-23 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13960 407d7337e227226515d9bdf2db7b65a3 328 Gene3D G3DSA:3.40.109.10 4 116 6.8E-13 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13960 407d7337e227226515d9bdf2db7b65a3 328 SUPERFAMILY SSF55469 239 325 4.0E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 SUPERFAMILY SSF56645 2 243 2.62E-68 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Gene3D G3DSA:1.20.140.10 221 401 1.5E-37 T 29-03-2018 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 SUPERFAMILY SSF47203 232 393 6.12E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 387 2.2E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Gene3D G3DSA:2.40.110.10 121 220 5.4E-32 T 29-03-2018 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 1.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 4.5E-24 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS18945 5baf2906afbe71bc2150c15127ada6c0 402 Gene3D G3DSA:1.10.540.10 1 120 3.3E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21500 afbd6023369b1fe2c23a49cf6540f29f 294 Gene3D G3DSA:3.40.50.300 42 238 3.1E-35 T 29-03-2018 MSG_RS21500 afbd6023369b1fe2c23a49cf6540f29f 294 Pfam PF03308 ArgK protein 34 250 1.0E-70 T 29-03-2018 MSG_RS21500 afbd6023369b1fe2c23a49cf6540f29f 294 SUPERFAMILY SSF52540 6 287 3.11E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02265 392002525ef710e410fed8c43e713ad7 181 Gene3D G3DSA:3.40.630.30 1 181 6.9E-30 T 29-03-2018 MSG_RS02265 392002525ef710e410fed8c43e713ad7 181 SUPERFAMILY SSF55729 14 181 6.71E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS02265 392002525ef710e410fed8c43e713ad7 181 Pfam PF13527 Acetyltransferase (GNAT) domain 17 131 3.2E-13 T 29-03-2018 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 Pfam PF00800 Prephenate dehydratase 4 189 5.8E-45 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 Gene3D G3DSA:3.40.190.10 1 100 7.0E-27 T 29-03-2018 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 Pfam PF01842 ACT domain 204 267 2.7E-8 T 29-03-2018 IPR002912 ACT domain MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 Gene3D G3DSA:3.30.70.260 193 287 1.2E-28 T 29-03-2018 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 SUPERFAMILY SSF53850 3 196 1.4E-45 T 29-03-2018 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 PIRSF PIRSF001500 1 283 8.3E-60 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 Gene3D G3DSA:3.40.190.10 101 172 1.2E-19 T 29-03-2018 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 229 236 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MSG_RS24300 127e6211b22e73fd38f633765c94e9b4 318 SUPERFAMILY SSF55021 184 281 1.01E-24 T 29-03-2018 MSG_RS01835 32509f182f3a6621654b9fed05a0a9e4 171 TIGRFAM TIGR04338 HEXXH_Rv0185: putative metallohydrolase, TIGR04338 family 9 169 4.4E-70 T 29-03-2018 IPR027595 Conserved hypothetical protein CHP04338 MSG_RS16300 b05bb4735ad894d6002998e7dd6f5998 272 Gene3D G3DSA:1.20.1080.10 14 270 9.0E-41 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MSG_RS16300 b05bb4735ad894d6002998e7dd6f5998 272 Pfam PF01226 Formate/nitrite transporter 24 253 1.2E-34 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 MSG_RS12340 2f7ed80cfe1176a0b224e31c5639cfb5 284 SUPERFAMILY SSF103481 46 121 4.71E-6 T 29-03-2018 MSG_RS12340 2f7ed80cfe1176a0b224e31c5639cfb5 284 SUPERFAMILY SSF103481 193 275 7.72E-5 T 29-03-2018 MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 SUPERFAMILY SSF51735 14 258 4.35E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 2.1E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 163 256 1.1E-17 T 29-03-2018 MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 Gene3D G3DSA:3.40.50.720 3 260 1.8E-47 T 29-03-2018 MSG_RS21445 a35a772aa3220340c1c8f39478b16211 276 Pfam PF00106 short chain dehydrogenase 15 129 4.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS08710 ae56aa828be6a34cd276347972f7194a 418 Pfam PF02720 Domain of unknown function (DUF222) 21 303 7.1E-59 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS08710 ae56aa828be6a34cd276347972f7194a 418 Pfam PF01844 HNH endonuclease 311 349 1.4E-6 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MSG_RS08710 ae56aa828be6a34cd276347972f7194a 418 SMART SM00507 294 345 7.3E-13 T 29-03-2018 IPR003615 HNH nuclease MSG_RS08710 ae56aa828be6a34cd276347972f7194a 418 Gene3D G3DSA:3.40.1800.10 285 352 4.8E-10 T 29-03-2018 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 204 219 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 33 57 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 142 166 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 168 193 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 64 81 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 106 131 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 PRINTS PR00118 Beta-lactamase class A signature 219 234 8.4E-59 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 SUPERFAMILY SSF56601 32 284 2.36E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 ProSitePatterns PS00146 Beta-lactamase class-A active site. 66 81 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 Pfam PF13354 Beta-lactamase enzyme family 54 257 5.2E-41 T 29-03-2018 MSG_RS08645 4d98fc7cda28d1e21e15dbc74cda2301 290 Gene3D G3DSA:3.40.710.10 27 286 1.2E-44 T 29-03-2018 MSG_RS00190 98862ecb3dcc3ea50df3b5e4397ef9c8 274 Pfam PF00877 NlpC/P60 family 178 263 2.0E-20 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MSG_RS00190 98862ecb3dcc3ea50df3b5e4397ef9c8 274 SUPERFAMILY SSF54001 157 266 9.81E-34 T 29-03-2018 MSG_RS00190 98862ecb3dcc3ea50df3b5e4397ef9c8 274 Gene3D G3DSA:3.90.1720.10 163 273 4.2E-30 T 29-03-2018 MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 SUPERFAMILY SSF46689 11 89 3.28E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.5E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 Gene3D G3DSA:1.10.357.10 8 206 1.8E-37 T 29-03-2018 MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 SUPERFAMILY SSF48498 92 203 1.17E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17830 84646dbb87ad5f7ac172d88ee44ca8d5 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.2E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 Gene3D G3DSA:2.30.33.40 1 99 1.0E-39 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 Hamap MF_00580 10 kDa chaperonin [groS]. 5 99 25.474 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 Pfam PF00166 Chaperonin 10 Kd subunit 5 98 1.3E-34 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 SUPERFAMILY SSF50129 4 99 5.93E-35 T 29-03-2018 IPR011032 GroES-like MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 PRINTS PR00297 10kDa chaperonin signature 64 76 1.5E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 PRINTS PR00297 10kDa chaperonin signature 28 49 1.5E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 PRINTS PR00297 10kDa chaperonin signature 6 21 1.5E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 PRINTS PR00297 10kDa chaperonin signature 85 98 1.5E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS05030 642dc530abdac17b83505b79d7a5eb58 100 SMART SM00883 5 98 1.8E-54 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MSG_RS19415 75e5ac3fe6216387ad68d482f55d66de 283 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 105 269 7.0E-24 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS19415 75e5ac3fe6216387ad68d482f55d66de 283 SMART SM00044 79 250 5.3E-6 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS19415 75e5ac3fe6216387ad68d482f55d66de 283 Gene3D G3DSA:3.30.70.1230 91 273 3.4E-38 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS19415 75e5ac3fe6216387ad68d482f55d66de 283 SUPERFAMILY SSF55073 104 278 3.66E-44 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS22590 ac028d815c769536098a1d61c072f076 311 Gene3D G3DSA:1.10.540.10 1 111 4.2E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22590 ac028d815c769536098a1d61c072f076 311 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 89 1.2E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22590 ac028d815c769536098a1d61c072f076 311 SUPERFAMILY SSF47203 179 310 1.32E-31 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22590 ac028d815c769536098a1d61c072f076 311 Gene3D G3DSA:1.20.140.10 165 311 1.4E-28 T 29-03-2018 MSG_RS22590 ac028d815c769536098a1d61c072f076 311 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 179 310 4.5E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22590 ac028d815c769536098a1d61c072f076 311 SUPERFAMILY SSF56645 2 118 2.96E-12 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS06620 b6ebe427fff43607b1fca7711f3a1439 293 SUPERFAMILY SSF47413 30 77 5.63E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS06620 b6ebe427fff43607b1fca7711f3a1439 293 Pfam PF13560 Helix-turn-helix domain 30 84 9.3E-10 T 29-03-2018 MSG_RS06620 b6ebe427fff43607b1fca7711f3a1439 293 SMART SM00530 10 82 3.8E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS06620 b6ebe427fff43607b1fca7711f3a1439 293 Gene3D G3DSA:1.10.260.40 2 96 3.3E-11 T 29-03-2018 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 Gene3D G3DSA:3.40.710.10 44 304 1.5E-32 T 29-03-2018 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 Pfam PF13354 Beta-lactamase enzyme family 68 277 9.9E-38 T 29-03-2018 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 221 236 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 123 148 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 159 183 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 80 97 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 49 73 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 238 253 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 PRINTS PR00118 Beta-lactamase class A signature 185 210 7.0E-49 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MSG_RS18350 43e4da87ec5139162c085ff1b3e2c855 309 SUPERFAMILY SSF56601 48 303 8.74E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 PIRSF PIRSF000443 2 378 2.3E-109 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 24 368 1.5E-126 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 Pfam PF00561 alpha/beta hydrolase fold 52 356 1.4E-29 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 Gene3D G3DSA:3.40.50.1820 26 369 2.6E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 SUPERFAMILY SSF53474 18 368 3.97E-88 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05365 54f95baa92fa634686c9df6732c51b4d 383 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 9 370 45.666 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 MSG_RS24625 3eba404a73df5f9aa54d37167c0b7e1f 172 Gene3D G3DSA:4.10.1080.10 45 172 6.5E-6 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MSG_RS24625 3eba404a73df5f9aa54d37167c0b7e1f 172 Gene3D G3DSA:4.10.1080.10 6 44 0.11 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MSG_RS24625 3eba404a73df5f9aa54d37167c0b7e1f 172 SUPERFAMILY SSF103647 20 70 2.88E-5 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MSG_RS24625 3eba404a73df5f9aa54d37167c0b7e1f 172 SUPERFAMILY SSF103647 102 168 8.76E-9 T 29-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MSG_RS17290 00bcbbac9a4e357d2f38f8241ef4af91 131 Pfam PF01152 Bacterial-like globin 7 124 1.0E-42 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 MSG_RS17290 00bcbbac9a4e357d2f38f8241ef4af91 131 Gene3D G3DSA:1.10.490.10 3 130 7.5E-33 T 29-03-2018 MSG_RS17290 00bcbbac9a4e357d2f38f8241ef4af91 131 SUPERFAMILY SSF46458 6 129 3.7E-35 T 29-03-2018 IPR009050 Globin-like MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 Pfam PF01553 Acyltransferase 264 391 7.8E-14 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 SMART SM00563 266 393 6.0E-14 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 PIRSF PIRSF000437 4 786 8.7E-173 T 29-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 SUPERFAMILY SSF69593 264 446 2.88E-11 T 29-03-2018 MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 Gene3D G3DSA:3.40.1130.10 246 474 3.0E-14 T 29-03-2018 MSG_RS17340 e0a1d8e3959c457248bc6b4b28ece5d4 791 PIRSF PIRSF500064 1 786 5.3E-180 T 29-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 MSG_RS18185 c04be94fb9a06289049044bc7a737c71 310 SUPERFAMILY SSF51197 5 291 5.1E-79 T 29-03-2018 MSG_RS18185 c04be94fb9a06289049044bc7a737c71 310 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 9 275 1.1E-51 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MSG_RS18185 c04be94fb9a06289049044bc7a737c71 310 Gene3D G3DSA:3.60.130.10 1 295 5.5E-69 T 29-03-2018 MSG_RS20735 58cf95630e7e88e95ca50f8c301f70aa 94 Pfam PF10801 Protein of unknown function (DUF2537) 13 90 5.7E-29 T 29-03-2018 IPR024244 Protein of unknown function DUF2537 MSG_RS20735 58cf95630e7e88e95ca50f8c301f70aa 94 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 40 74 0.001 T 29-03-2018 IPR024244 Protein of unknown function DUF2537 MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 Pfam PF00561 alpha/beta hydrolase fold 40 284 4.3E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 Gene3D G3DSA:3.40.50.1820 4 310 3.7E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 SUPERFAMILY SSF53474 22 296 9.49E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.4E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.4E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS08970 d5e119b8db2c36e34764f31fc56d0cfe 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 1.4E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS08960 37dd3b303bc6491ded1f9de0e39734d0 161 Pfam PF08768 Domain of unknown function (DUF1794) 9 159 7.8E-44 T 29-03-2018 IPR014878 Domain of unknown function DUF1794 MSG_RS08960 37dd3b303bc6491ded1f9de0e39734d0 161 SUPERFAMILY SSF50814 5 159 1.35E-46 T 29-03-2018 IPR012674 Calycin MSG_RS08960 37dd3b303bc6491ded1f9de0e39734d0 161 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 1 161 27.55 T 29-03-2018 IPR022939 Uncharacterised protein family UPF0678 MSG_RS08960 37dd3b303bc6491ded1f9de0e39734d0 161 Gene3D G3DSA:2.40.128.20 1 161 7.0E-52 T 29-03-2018 IPR012674 Calycin MSG_RS02945 f9f02c519689c9c2761afd404a4fad8b 372 SUPERFAMILY SSF51679 4 113 4.18E-62 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02945 f9f02c519689c9c2761afd404a4fad8b 372 SUPERFAMILY SSF51679 154 366 4.18E-62 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02945 f9f02c519689c9c2761afd404a4fad8b 372 Pfam PF00296 Luciferase-like monooxygenase 12 339 7.5E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02945 f9f02c519689c9c2761afd404a4fad8b 372 Gene3D G3DSA:3.20.20.30 3 367 6.5E-86 T 29-03-2018 MSG_RS04080 ef54745709dafc849f9ef80e25b95313 159 PIRSF PIRSF018072 2 150 1.7E-54 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS04080 ef54745709dafc849f9ef80e25b95313 159 Hamap MF_00799 UPF0336 protein . 1 148 33.703 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS04080 ef54745709dafc849f9ef80e25b95313 159 Gene3D G3DSA:3.10.129.10 3 157 6.6E-28 T 29-03-2018 MSG_RS04080 ef54745709dafc849f9ef80e25b95313 159 SUPERFAMILY SSF54637 7 150 4.65E-35 T 29-03-2018 IPR029069 HotDog domain MSG_RS04080 ef54745709dafc849f9ef80e25b95313 159 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 6.3E-30 T 29-03-2018 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 Gene3D G3DSA:1.10.760.10 168 259 9.8E-14 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 Gene3D G3DSA:1.10.760.10 54 167 2.1E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 SUPERFAMILY SSF46626 161 252 3.75E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 SUPERFAMILY SSF46626 44 157 2.06E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 PIRSF PIRSF000007 8 295 1.1E-141 T 29-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 179 250 5.0E-8 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS15300 d6d5ef873a37ad3090918791c0d4143c 295 Pfam PF00034 Cytochrome c 79 125 2.2E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 MSG_RS17855 ef29f3666cf16d2a0b9d88a6a5718cda 347 Gene3D G3DSA:3.20.20.30 9 347 4.7E-50 T 29-03-2018 MSG_RS17855 ef29f3666cf16d2a0b9d88a6a5718cda 347 Pfam PF00296 Luciferase-like monooxygenase 20 322 4.5E-34 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS17855 ef29f3666cf16d2a0b9d88a6a5718cda 347 TIGRFAM TIGR03857 F420_MSMEG_2249: probable F420-dependent oxidoreductase, MSMEG_2249 family 9 336 2.5E-142 T 29-03-2018 IPR022378 F420-dependent oxidoreductase-predicted, MSMEG2249 MSG_RS17855 ef29f3666cf16d2a0b9d88a6a5718cda 347 SUPERFAMILY SSF51679 9 338 8.11E-47 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20905 d4e82ab31e855b624d21c4d4b733edf0 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 68 5.9E-10 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MSG_RS20905 d4e82ab31e855b624d21c4d4b733edf0 97 SUPERFAMILY SSF54909 3 92 3.63E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS20905 d4e82ab31e855b624d21c4d4b733edf0 97 Gene3D G3DSA:3.30.70.100 1 97 3.0E-14 T 29-03-2018 MSG_RS24695 dbfb51d454a454e1f51af00c6d6f692c 190 SMART SM00393 111 190 3.4E-24 T 29-03-2018 IPR001374 R3H domain GO:0003676 MSG_RS24695 dbfb51d454a454e1f51af00c6d6f692c 190 Gene3D G3DSA:3.30.1370.50 122 190 2.5E-18 T 29-03-2018 IPR001374 R3H domain GO:0003676 MSG_RS24695 dbfb51d454a454e1f51af00c6d6f692c 190 Pfam PF01424 R3H domain 130 187 4.7E-15 T 29-03-2018 IPR001374 R3H domain GO:0003676 MSG_RS24695 dbfb51d454a454e1f51af00c6d6f692c 190 Gene3D G3DSA:3.30.300.20 43 120 4.8E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS24695 dbfb51d454a454e1f51af00c6d6f692c 190 SUPERFAMILY SSF82708 136 188 6.67E-10 T 29-03-2018 IPR001374 R3H domain GO:0003676 MSG_RS01920 e5213e4a3041cece81042e4b6ca7220d 381 Pfam PF01594 AI-2E family transporter 22 346 3.7E-71 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 167 181 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 SUPERFAMILY SSF89095 355 499 2.27E-20 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 18 502 35.395 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 SMART SM00845 354 501 8.9E-50 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 SUPERFAMILY SSF55931 21 323 1.31E-111 T 29-03-2018 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 Pfam PF02637 GatB domain 357 498 4.3E-37 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 Gene3D G3DSA:1.10.10.410 441 500 8.0E-15 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 Pfam PF02934 GatB/GatE catalytic domain 22 316 6.3E-105 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MSG_RS07740 8c47238f52b752f100a76dd3eceaf293 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 19 497 5.8E-143 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 230 7.2E-90 T 29-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 SUPERFAMILY SSF56235 2 230 4.05E-18 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 Gene3D G3DSA:3.60.20.10 193 230 0.049 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 Gene3D G3DSA:3.60.20.10 1 192 7.1E-23 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 Pfam PF13522 Glutamine amidotransferase domain 73 201 1.6E-14 T 29-03-2018 MSG_RS23345 60d082fa258fd26ed965747288fa9c49 237 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 230 35.351 T 29-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 MSG_RS12910 d60ba4ae129ac58bd6cb3196856b7750 346 Pfam PF00571 CBS domain 233 276 0.0035 T 29-03-2018 IPR000644 CBS domain MSG_RS12910 d60ba4ae129ac58bd6cb3196856b7750 346 Pfam PF00571 CBS domain 290 336 0.0014 T 29-03-2018 IPR000644 CBS domain MSG_RS12910 d60ba4ae129ac58bd6cb3196856b7750 346 SUPERFAMILY SSF54631 209 344 4.8E-18 T 29-03-2018 MSG_RS12910 d60ba4ae129ac58bd6cb3196856b7750 346 Gene3D G3DSA:3.10.580.10 198 346 1.9E-23 T 29-03-2018 MSG_RS12910 d60ba4ae129ac58bd6cb3196856b7750 346 Pfam PF01595 Domain of unknown function DUF21 8 202 3.8E-39 T 29-03-2018 IPR002550 Domain of unknown function DUF21 MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 SMART SM00481 98 177 5.3E-19 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 Pfam PF14716 Helix-hairpin-helix domain 5 68 3.6E-13 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 SUPERFAMILY SSF47802 3 82 1.06E-13 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 Pfam PF02811 PHP domain 99 188 7.3E-10 T 29-03-2018 IPR004013 PHP domain GO:0003824 MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 SUPERFAMILY SSF89550 97 327 8.76E-51 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 Gene3D G3DSA:3.20.20.140 99 325 9.2E-48 T 29-03-2018 MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 PIRSF PIRSF036978 1 335 7.4E-196 T 29-03-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 MSG_RS24395 af99754b2c92bece0e97fc099ff0c757 335 Gene3D G3DSA:1.10.150.110 2 83 4.7E-13 T 29-03-2018 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 Gene3D G3DSA:3.30.300.30 498 611 1.8E-16 T 29-03-2018 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 Pfam PF00501 AMP-binding enzyme 58 502 2.1E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 Gene3D G3DSA:2.30.38.10 387 495 2.2E-15 T 29-03-2018 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 Gene3D G3DSA:3.40.50.980 31 203 7.0E-31 T 29-03-2018 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 Gene3D G3DSA:3.40.50.980 204 378 4.7E-27 T 29-03-2018 MSG_RS18020 f2875cd70f4efdcaec757fa870f3d90c 618 SUPERFAMILY SSF56801 34 613 7.85E-95 T 29-03-2018 MSG_RS12470 6b1858ed171121c7fe9f249f47765920 168 Gene3D G3DSA:3.30.70.100 98 168 3.6E-6 T 29-03-2018 MSG_RS12470 6b1858ed171121c7fe9f249f47765920 168 SUPERFAMILY SSF54909 103 164 5.7E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 Gene3D G3DSA:3.40.50.1100 140 308 2.0E-62 T 29-03-2018 MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 Gene3D G3DSA:3.40.50.1100 42 139 9.3E-34 T 29-03-2018 MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 294 1.1E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 SUPERFAMILY SSF53686 3 306 2.23E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 305 3.3E-143 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MSG_RS16580 6fb0e7d07d85b6a49ca443baa6c34cff 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 305 1.1E-137 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MSG_RS18865 a94478be31247cb79bab498fcbd0d935 334 Gene3D G3DSA:3.90.550.10 20 293 1.2E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS18865 a94478be31247cb79bab498fcbd0d935 334 SUPERFAMILY SSF53448 49 291 5.56E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS18865 a94478be31247cb79bab498fcbd0d935 334 Pfam PF00535 Glycosyl transferase family 2 50 164 1.1E-10 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 Gene3D G3DSA:3.40.50.620 60 246 1.1E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 PIRSF PIRSF000857 1 246 1.4E-82 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 57 243 2.4E-73 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 4 245 36.371 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 54 220 3.2E-44 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 55 244 2.7E-51 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MSG_RS16865 c763020c9170a8409ab7293561c4c974 246 SUPERFAMILY SSF52402 54 209 3.41E-38 T 29-03-2018 MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 292 1.4E-76 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 3.3E-90 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 Gene3D G3DSA:1.10.287.950 142 300 2.1E-5 T 29-03-2018 MSG_RS14265 3e47ef63d37c03b4aec388f6c8c4714e 515 Pfam PF02470 MlaD protein 41 112 1.2E-12 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Gene3D G3DSA:3.40.50.980 180 329 3.4E-27 T 29-03-2018 MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Gene3D G3DSA:3.40.50.980 18 179 5.9E-33 T 29-03-2018 MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Gene3D G3DSA:2.30.38.10 334 410 1.4E-16 T 29-03-2018 MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 3.8E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 SUPERFAMILY SSF56801 17 512 7.59E-117 T 29-03-2018 MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Gene3D G3DSA:3.30.300.30 411 514 2.0E-20 T 29-03-2018 MSG_RS17680 de3125c5b80dbd10d16b25c137a7970d 527 Pfam PF00501 AMP-binding enzyme 26 415 6.1E-70 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS08290 31bef796fc6b5cc3c9d57b184f028705 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 127 4.1E-32 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting MSG_RS08290 31bef796fc6b5cc3c9d57b184f028705 283 Gene3D G3DSA:3.40.50.80 128 283 4.8E-42 T 29-03-2018 MSG_RS08290 31bef796fc6b5cc3c9d57b184f028705 283 Gene3D G3DSA:2.40.30.10 2 127 2.8E-26 T 29-03-2018 MSG_RS08290 31bef796fc6b5cc3c9d57b184f028705 283 SUPERFAMILY SSF63380 8 132 6.08E-8 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS08290 31bef796fc6b5cc3c9d57b184f028705 283 Pfam PF04954 Siderophore-interacting protein 134 262 2.3E-33 T 29-03-2018 IPR007037 Siderophore-interacting protein MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 Pfam PF01895 PhoU domain 122 204 2.0E-11 T 29-03-2018 IPR026022 PhoU domain MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 Pfam PF01895 PhoU domain 17 103 9.2E-12 T 29-03-2018 IPR026022 PhoU domain MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 Gene3D G3DSA:1.20.58.220 111 221 1.9E-16 T 29-03-2018 MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 PIRSF PIRSF003107 1 217 1.2E-50 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 Gene3D G3DSA:1.20.58.220 1 110 6.6E-16 T 29-03-2018 MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 6.2E-59 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MSG_RS21670 f0b0960ad75d34db386e640f3a7ede0e 222 SUPERFAMILY SSF109755 2 214 1.47E-53 T 29-03-2018 MSG_RS01075 668015783bddbe05a22e12aaa0628859 207 SUPERFAMILY SSF88946 23 79 7.46E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS01075 668015783bddbe05a22e12aaa0628859 207 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS01075 668015783bddbe05a22e12aaa0628859 207 Gene3D G3DSA:1.10.1740.10 14 81 4.6E-15 T 29-03-2018 MSG_RS01075 668015783bddbe05a22e12aaa0628859 207 Pfam PF04542 Sigma-70 region 2 25 76 1.2E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05890 27f52f2aeb68e2f280ee602c4d472532 232 Gene3D G3DSA:1.10.260.40 71 100 1.3E-10 T 29-03-2018 MSG_RS05890 27f52f2aeb68e2f280ee602c4d472532 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 50 93 8.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05890 27f52f2aeb68e2f280ee602c4d472532 232 Gene3D G3DSA:1.10.357.10 101 225 3.3E-6 T 29-03-2018 MSG_RS05890 27f52f2aeb68e2f280ee602c4d472532 232 Gene3D G3DSA:1.10.10.60 17 70 5.1E-11 T 29-03-2018 MSG_RS05890 27f52f2aeb68e2f280ee602c4d472532 232 SUPERFAMILY SSF46689 41 112 6.48E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS23305 9632e9b009447ebe96be54f40488da3a 333 Pfam PF01944 Stage II sporulation protein M 111 284 2.6E-35 T 29-03-2018 IPR002798 Stage II sporulation protein M-like MSG_RS10315 47b82a70706d13aa79817b786215431f 160 Pfam PF01047 MarR family 42 99 3.3E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS10315 47b82a70706d13aa79817b786215431f 160 Gene3D G3DSA:1.10.10.10 1 150 2.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10315 47b82a70706d13aa79817b786215431f 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 108 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MSG_RS10315 47b82a70706d13aa79817b786215431f 160 SMART SM00347 35 135 7.6E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS10315 47b82a70706d13aa79817b786215431f 160 SUPERFAMILY SSF46785 10 148 3.63E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19685 57182ada0cbbcea49e90a12fc6fa917a 142 SUPERFAMILY SSF52821 13 120 2.33E-14 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS19685 57182ada0cbbcea49e90a12fc6fa917a 142 Pfam PF00581 Rhodanese-like domain 22 116 1.1E-4 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS19685 57182ada0cbbcea49e90a12fc6fa917a 142 SMART SM00450 17 122 1.0E-7 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS19685 57182ada0cbbcea49e90a12fc6fa917a 142 Gene3D G3DSA:3.40.250.10 1 129 3.9E-13 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 Gene3D G3DSA:2.40.10.10 126 220 8.8E-8 T 29-03-2018 MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 Gene3D G3DSA:2.40.10.10 46 125 9.7E-15 T 29-03-2018 MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 SUPERFAMILY SSF50494 49 218 6.33E-21 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 72 86 4.0E-5 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 194 208 4.0E-5 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 MSG_RS22170 5a2fdc2def82ecc19cbf2821fa9e2518 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 134 154 4.0E-5 T 29-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 Gene3D G3DSA:1.10.357.10 86 228 7.3E-15 T 29-03-2018 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 83 4.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 SUPERFAMILY SSF48498 105 208 1.89E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 Gene3D G3DSA:1.10.10.60 19 60 2.6E-11 T 29-03-2018 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 1.1E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 Gene3D G3DSA:1.10.260.40 61 85 4.9E-10 T 29-03-2018 MSG_RS07365 69e3be2cc5d55618e58a04e1724d8ae4 249 SUPERFAMILY SSF46689 26 100 3.18E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 Gene3D G3DSA:3.40.50.300 1 183 1.4E-37 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 PRINTS PR01100 Shikimate kinase family signature 57 65 5.3E-20 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 PRINTS PR01100 Shikimate kinase family signature 95 112 5.3E-20 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 PRINTS PR01100 Shikimate kinase family signature 75 84 5.3E-20 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 PRINTS PR01100 Shikimate kinase family signature 29 42 5.3E-20 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 PRINTS PR01100 Shikimate kinase family signature 5 20 5.3E-20 T 29-03-2018 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 26.371 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MSG_RS09915 93974ccbc9e36319de919781d5285015 183 SUPERFAMILY SSF52540 3 165 2.13E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS09915 93974ccbc9e36319de919781d5285015 183 Pfam PF01202 Shikimate kinase 11 166 1.2E-43 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MSG_RS17605 edb4b226d409876c7c255ca7434d2f9a 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17605 edb4b226d409876c7c255ca7434d2f9a 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17605 edb4b226d409876c7c255ca7434d2f9a 218 Gene3D G3DSA:1.10.357.10 10 215 8.0E-34 T 29-03-2018 MSG_RS17605 edb4b226d409876c7c255ca7434d2f9a 218 SUPERFAMILY SSF46689 17 88 1.49E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17605 edb4b226d409876c7c255ca7434d2f9a 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 1.2E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 59 1094 12.84 T 29-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 SMART SM00481 60 127 2.4E-24 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Pfam PF14579 Helix-hairpin-helix motif 840 928 2.0E-24 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 351 764 6.4E-142 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Gene3D G3DSA:2.40.50.140 993 1087 2.3E-5 T 29-03-2018 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Pfam PF02811 PHP domain 61 232 1.1E-29 T 29-03-2018 IPR004013 PHP domain GO:0003824 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Gene3D G3DSA:1.10.150.280 848 947 0.0024 T 29-03-2018 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 60 932 1.8E-192 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 SUPERFAMILY SSF89550 60 270 1.2E-20 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MSG_RS05225 316ca6d2b41a06d871870660138aa2ec 1094 Gene3D G3DSA:3.20.20.140 57 291 1.0E-37 T 29-03-2018 MSG_RS17480 a717c677865795b69121f269b5c73822 261 Pfam PF05423 Mycobacterium membrane protein 171 250 1.7E-6 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS13980 23d085d8e6aa12baca6913067035aa1a 326 SUPERFAMILY SSF55469 7 34 1.96E-14 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13980 23d085d8e6aa12baca6913067035aa1a 326 SUPERFAMILY SSF55469 153 325 1.96E-14 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13980 23d085d8e6aa12baca6913067035aa1a 326 SUPERFAMILY SSF55469 9 87 2.59E-5 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13980 23d085d8e6aa12baca6913067035aa1a 326 Gene3D G3DSA:3.40.109.10 3 138 2.5E-13 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS13980 23d085d8e6aa12baca6913067035aa1a 326 Gene3D G3DSA:3.40.109.10 139 325 1.4E-23 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 Gene3D G3DSA:3.40.190.10 231 374 2.9E-14 T 29-03-2018 MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 PIRSF PIRSF002756 7 374 9.1E-117 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 SUPERFAMILY SSF53850 56 373 3.1E-76 T 29-03-2018 MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 Pfam PF12849 PBP superfamily domain 55 344 6.6E-49 T 29-03-2018 IPR024370 PBP domain MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 58 373 1.8E-81 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS21690 0f894e0bae6a2dd202af3d80607d304b 374 Gene3D G3DSA:3.40.190.10 55 230 1.5E-27 T 29-03-2018 MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 SUPERFAMILY SSF52540 89 379 6.83E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 SMART SM00487 33 244 3.8E-49 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 Pfam PF00271 Helicase conserved C-terminal domain 252 361 2.5E-30 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 SMART SM00490 280 361 1.6E-34 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 173 181 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 Gene3D G3DSA:3.40.50.300 7 243 5.9E-53 T 29-03-2018 MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 Gene3D G3DSA:3.40.50.300 244 510 1.6E-46 T 29-03-2018 MSG_RS06225 4a0a9fd69cda7c16bff8b4070e00910c 512 Pfam PF00270 DEAD/DEAH box helicase 39 210 8.2E-49 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MSG_RS18075 f8cf28fe2b1e991bd519fe31600ae8b1 260 Gene3D G3DSA:3.60.15.10 2 254 2.1E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS18075 f8cf28fe2b1e991bd519fe31600ae8b1 260 Pfam PF12706 Beta-lactamase superfamily domain 50 222 1.7E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS18075 f8cf28fe2b1e991bd519fe31600ae8b1 260 SUPERFAMILY SSF56281 4 254 1.15E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS21890 237307341699eff94cdde030af9b257e 201 Gene3D G3DSA:1.10.10.60 3 66 6.2E-16 T 29-03-2018 MSG_RS21890 237307341699eff94cdde030af9b257e 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 4.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21890 237307341699eff94cdde030af9b257e 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21890 237307341699eff94cdde030af9b257e 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21890 237307341699eff94cdde030af9b257e 201 Gene3D G3DSA:1.10.357.10 67 200 1.0E-17 T 29-03-2018 MSG_RS21890 237307341699eff94cdde030af9b257e 201 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 185 1.3E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21890 237307341699eff94cdde030af9b257e 201 SUPERFAMILY SSF46689 10 74 4.3E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21890 237307341699eff94cdde030af9b257e 201 SUPERFAMILY SSF48498 77 187 5.84E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS17960 b8f5458f51697c4816aaf3d314cfc483 335 Gene3D G3DSA:3.20.20.70 1 333 1.5E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS17960 b8f5458f51697c4816aaf3d314cfc483 335 SMART SM01130 14 331 6.2E-31 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS17960 b8f5458f51697c4816aaf3d314cfc483 335 Pfam PF00701 Dihydrodipicolinate synthetase family 16 204 3.3E-15 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MSG_RS17960 b8f5458f51697c4816aaf3d314cfc483 335 SUPERFAMILY SSF51569 13 332 4.5E-38 T 29-03-2018 MSG_RS12930 c548b3fc0289fa0683f78f4823df9860 316 Pfam PF01435 Peptidase family M48 142 208 5.6E-11 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MSG_RS12930 c548b3fc0289fa0683f78f4823df9860 316 Gene3D G3DSA:3.30.2010.10 107 204 5.2E-15 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 322 340 3.1E-36 T 29-03-2018 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 SUPERFAMILY SSF51905 276 387 3.34E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 SUPERFAMILY SSF51905 11 185 3.34E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 Pfam PF01494 FAD binding domain 11 351 3.2E-66 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS14320 72609ac2a4220137ae80c05edd887fa9 530 Gene3D G3DSA:3.50.50.60 9 381 6.4E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03060 ebe2762075c30042d5ae9f75c3273ac9 489 Pfam PF04389 Peptidase family M28 242 461 1.4E-25 T 29-03-2018 IPR007484 Peptidase M28 MSG_RS03060 ebe2762075c30042d5ae9f75c3273ac9 489 Gene3D G3DSA:3.40.630.10 37 473 2.6E-44 T 29-03-2018 MSG_RS03060 ebe2762075c30042d5ae9f75c3273ac9 489 Pfam PF02225 PA domain 132 220 7.8E-7 T 29-03-2018 IPR003137 PA domain MSG_RS03060 ebe2762075c30042d5ae9f75c3273ac9 489 SUPERFAMILY SSF53187 37 89 1.18E-42 T 29-03-2018 MSG_RS03060 ebe2762075c30042d5ae9f75c3273ac9 489 SUPERFAMILY SSF53187 226 470 1.18E-42 T 29-03-2018 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 Gene3D G3DSA:3.90.1150.10 270 409 8.0E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 SUPERFAMILY SSF53383 38 408 1.81E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 21 409 51.525 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 Gene3D G3DSA:3.40.640.10 17 269 6.5E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 PIRSF PIRSF001434 14 409 3.3E-113 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 20 408 6.3E-196 T 29-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MSG_RS02885 6e4f7539fe4ce2612a887a591a49646a 409 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 21 408 7.1E-131 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS04680 0bb753a5a35d745e3fcb764de9c6014c 309 Pfam PF04072 Leucine carboxyl methyltransferase 19 208 2.2E-63 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS04680 0bb753a5a35d745e3fcb764de9c6014c 309 SUPERFAMILY SSF53335 15 292 9.41E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04680 0bb753a5a35d745e3fcb764de9c6014c 309 Gene3D G3DSA:3.40.50.150 2 300 1.4E-58 T 29-03-2018 MSG_RS04680 0bb753a5a35d745e3fcb764de9c6014c 309 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 278 1.5E-79 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 402 411 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 SUPERFAMILY SSF48264 6 460 5.89E-103 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 Pfam PF00067 Cytochrome P450 7 454 5.1E-78 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 Gene3D G3DSA:1.10.630.10 2 461 2.7E-108 T 29-03-2018 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00385 P450 superfamily signature 400 409 2.4E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00385 P450 superfamily signature 409 420 2.4E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00385 P450 superfamily signature 324 335 2.4E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00385 P450 superfamily signature 269 286 2.4E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 399 409 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 364 388 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 409 432 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 13 32 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 323 341 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 258 275 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS03255 6b6be1816a5296ef17e148278e4e1e71 461 PRINTS PR00463 E-class P450 group I signature 278 304 1.3E-23 T 29-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 SUPERFAMILY SSF74650 5 271 1.57E-65 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 698 750 3.9E-13 T 29-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Gene3D G3DSA:2.60.420.10 680 753 2.8E-20 T 29-03-2018 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 693 1.5E-140 T 29-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 PIRSF PIRSF036289 1 763 2.5E-218 T 29-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 SUPERFAMILY SSF48208 280 744 1.53E-113 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Gene3D G3DSA:1.50.10.10 321 679 1.4E-98 T 29-03-2018 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 9.8E-59 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MSG_RS05140 78154492884d2ae6e84866f67fb5f53f 788 Gene3D G3DSA:2.70.98.40 3 274 1.6E-77 T 29-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Pfam PF00501 AMP-binding enzyme 38 432 6.6E-69 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Gene3D G3DSA:2.30.38.10 347 427 1.2E-12 T 29-03-2018 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 SUPERFAMILY SSF56801 28 528 7.59E-109 T 29-03-2018 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Gene3D G3DSA:3.30.300.30 431 540 2.3E-16 T 29-03-2018 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 6.6E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Gene3D G3DSA:3.40.50.980 30 193 8.2E-30 T 29-03-2018 MSG_RS12350 c6dca19a6b374caac8d6328c1beba175 540 Gene3D G3DSA:3.40.50.980 194 346 5.7E-38 T 29-03-2018 MSG_RS20040 e91d57d77fd2cca3f1e7332e073a7deb 491 Pfam PF04932 O-Antigen ligase 248 405 7.1E-8 T 29-03-2018 IPR007016 O-antigen ligase-related MSG_RS06540 bcb1a5e8cf23146ad6b94917461f5af0 243 SUPERFAMILY SSF53335 40 192 2.15E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS06540 bcb1a5e8cf23146ad6b94917461f5af0 243 Gene3D G3DSA:3.40.50.150 36 220 7.6E-21 T 29-03-2018 MSG_RS06540 bcb1a5e8cf23146ad6b94917461f5af0 243 Pfam PF05401 Nodulation protein S (NodS) 52 160 8.8E-14 T 29-03-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 MSG_RS17540 f95dbb87f55814cfc1eba7ad43ea4d33 269 SUPERFAMILY SSF161098 75 260 9.29E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS17540 f95dbb87f55814cfc1eba7ad43ea4d33 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 259 5.6E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS17540 f95dbb87f55814cfc1eba7ad43ea4d33 269 Gene3D G3DSA:1.10.3720.10 28 269 9.4E-24 T 29-03-2018 MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 Pfam PF00106 short chain dehydrogenase 13 195 9.4E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 Gene3D G3DSA:3.40.50.720 2 262 2.0E-55 T 29-03-2018 MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-29 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS13040 792407bb61e559ee8b000998b6f4b6ac 280 SUPERFAMILY SSF51735 9 249 5.92E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15660 7f011358634d6765a21f226d8b4c7b9c 79 Pfam PF00550 Phosphopantetheine attachment site 3 57 8.5E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS15660 7f011358634d6765a21f226d8b4c7b9c 79 SUPERFAMILY SSF47336 2 70 2.09E-5 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS15660 7f011358634d6765a21f226d8b4c7b9c 79 Gene3D G3DSA:1.10.1200.10 1 74 6.3E-5 T 29-03-2018 MSG_RS08295 b2db7be18440634bebe20f05ba29a97f 386 SUPERFAMILY SSF51395 25 382 1.1E-87 T 29-03-2018 MSG_RS08295 b2db7be18440634bebe20f05ba29a97f 386 Gene3D G3DSA:3.20.20.70 24 385 1.9E-97 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS08295 b2db7be18440634bebe20f05ba29a97f 386 Pfam PF01070 FMN-dependent dehydrogenase 33 383 3.2E-110 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MSG_RS08295 b2db7be18440634bebe20f05ba29a97f 386 PIRSF PIRSF000138 6 386 5.4E-113 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 Gene3D G3DSA:1.10.10.60 1 60 4.1E-13 T 29-03-2018 MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 SUPERFAMILY SSF48498 85 181 1.11E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 Gene3D G3DSA:1.10.357.10 61 187 2.3E-21 T 29-03-2018 MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 Pfam PF13305 WHG domain 90 170 7.8E-16 T 29-03-2018 IPR025996 WHG domain MSG_RS11875 3e2ea84d086f227e167be0f75216952f 191 SUPERFAMILY SSF46689 6 80 9.75E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 SUPERFAMILY SSF47203 218 362 4.83E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 361 6.1E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 SUPERFAMILY SSF56645 1 217 3.8E-43 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 Gene3D G3DSA:1.10.540.10 1 118 5.4E-28 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 Gene3D G3DSA:1.20.140.10 211 362 1.5E-31 T 29-03-2018 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 2.4E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS18960 fb022449a06b1bc931d8b4209338b529 369 Gene3D G3DSA:2.40.110.10 119 210 1.3E-12 T 29-03-2018 MSG_RS12360 07a6fb20472c076f6723fa3c08deaf9f 422 Gene3D G3DSA:3.20.20.140 32 408 3.3E-62 T 29-03-2018 MSG_RS12360 07a6fb20472c076f6723fa3c08deaf9f 422 SUPERFAMILY SSF51556 37 66 6.24E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS12360 07a6fb20472c076f6723fa3c08deaf9f 422 SUPERFAMILY SSF51556 108 407 6.24E-66 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS12360 07a6fb20472c076f6723fa3c08deaf9f 422 Pfam PF04909 Amidohydrolase 89 407 8.8E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 PRINTS PR01217 Proline rich extensin signature 420 436 3.6E-11 T 29-03-2018 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 PRINTS PR01217 Proline rich extensin signature 378 390 3.6E-11 T 29-03-2018 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 PRINTS PR01217 Proline rich extensin signature 441 457 3.6E-11 T 29-03-2018 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 PRINTS PR01217 Proline rich extensin signature 397 418 3.6E-11 T 29-03-2018 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 PRINTS PR01217 Proline rich extensin signature 343 359 3.6E-11 T 29-03-2018 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 Pfam PF13406 Transglycosylase SLT domain 196 245 1.1E-8 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 SUPERFAMILY SSF53955 108 280 5.2E-35 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 ProSitePatterns PS00032 'Homeobox' antennapedia-type protein signature. 344 349 - T 29-03-2018 IPR001827 Homeobox protein, antennapedia type, conserved site GO:0003677|GO:0003700|GO:0006355 MSG_RS18780 5a549a5fac35d4f0cb2f0ef94f42c406 457 Gene3D G3DSA:1.10.530.10 120 354 3.2E-27 T 29-03-2018 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 320 3.3E-109 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 ProSitePatterns PS01016 Glycoprotease family signature. 101 121 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 SUPERFAMILY SSF53067 6 126 1.29E-23 T 29-03-2018 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 314 7.9E-84 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 Gene3D G3DSA:3.30.420.40 147 297 1.8E-17 T 29-03-2018 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 Gene3D G3DSA:3.30.420.40 4 146 8.0E-31 T 29-03-2018 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 Pfam PF00814 Glycoprotease family 31 314 2.8E-83 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 SUPERFAMILY SSF53067 107 318 6.8E-30 T 29-03-2018 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 81 101 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 121 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS05025 16360aa3792b203e27dc8ef74c3d2f21 346 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 340 59.135 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 Pfam PF00582 Universal stress protein family 10 148 9.4E-26 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 Pfam PF00582 Universal stress protein family 161 292 2.0E-26 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 Gene3D G3DSA:3.40.50.620 151 292 2.9E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 SUPERFAMILY SSF52402 160 292 1.09E-31 T 29-03-2018 MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 PRINTS PR01438 Universal stress protein signature 270 292 3.8E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 PRINTS PR01438 Universal stress protein signature 252 264 3.8E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 PRINTS PR01438 Universal stress protein signature 158 176 3.8E-18 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 Gene3D G3DSA:3.40.50.620 3 150 7.5E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13875 9d86d4fd2aa4e15233093acc99dd4120 292 SUPERFAMILY SSF52402 10 150 1.59E-30 T 29-03-2018 MSG_RS01390 41867821739882360dbd636b020cf4ea 142 Pfam PF05423 Mycobacterium membrane protein 8 142 8.5E-46 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS19325 ade74a6a588bf8c0b0d9f1ec3164d420 499 Pfam PF03972 MmgE/PrpD family 17 469 2.0E-125 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS19325 ade74a6a588bf8c0b0d9f1ec3164d420 499 SUPERFAMILY SSF103378 17 475 1.09E-119 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS19325 ade74a6a588bf8c0b0d9f1ec3164d420 499 Gene3D G3DSA:1.10.4100.10 5 323 3.5E-77 T 29-03-2018 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 207 484 4.9E-87 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 Gene3D G3DSA:3.30.360.10 207 489 8.5E-96 T 29-03-2018 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 Gene3D G3DSA:3.40.50.720 26 206 1.7E-53 T 29-03-2018 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 SUPERFAMILY SSF51735 19 208 1.95E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PIRSF PIRSF000110 12 488 2.2E-138 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 SUPERFAMILY SSF55347 195 490 3.6E-92 T 29-03-2018 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 496 77.304 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 332 358 1.8E-36 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 185 213 1.8E-36 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 255 271 1.8E-36 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 174 1.8E-36 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 237 254 1.8E-36 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 205 9.6E-44 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 484 1.2E-130 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS13670 a3d6fce22eb0b2f1365a57eb4230e554 499 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 195 201 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 Gene3D G3DSA:3.40.50.720 1 249 2.8E-48 T 29-03-2018 MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 SUPERFAMILY SSF51735 4 245 2.11E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 205 7.2E-4 T 29-03-2018 MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 Pfam PF00106 short chain dehydrogenase 10 201 4.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 9.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 9.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 9.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 9.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01140 f9067bc72e4cb803fb5f410e546c432d 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 9.9E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 SUPERFAMILY SSF47203 236 389 6.88E-56 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 133 145 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 126 8.1E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 387 6.3E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Gene3D G3DSA:2.40.110.10 130 227 9.5E-39 T 29-03-2018 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Gene3D G3DSA:1.20.140.10 228 389 1.8E-60 T 29-03-2018 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 SUPERFAMILY SSF56645 13 250 1.83E-76 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 PIRSF PIRSF016578 133 388 4.9E-14 T 29-03-2018 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 PIRSF PIRSF016578 9 106 5.9E-9 T 29-03-2018 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Gene3D G3DSA:1.10.540.10 2 129 1.8E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS05735 a4b453a176ffed8c841abe65a72e4a5f 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 226 8.5E-29 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Gene3D G3DSA:2.40.110.10 124 220 4.2E-37 T 29-03-2018 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 357 376 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Gene3D G3DSA:1.20.140.10 221 405 2.4E-51 T 29-03-2018 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 SUPERFAMILY SSF56645 2 230 4.32E-55 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 113 8.3E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 220 4.8E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 255 398 2.5E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 SUPERFAMILY SSF47203 256 399 1.11E-48 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00175 62651dc0c0f4fd62c42b630a8c6483c3 460 Gene3D G3DSA:1.10.540.10 1 116 8.4E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS04395 f58ea028e8f3e9f84948d9875040e881 423 SUPERFAMILY SSF52777 50 123 2.33E-5 T 29-03-2018 MSG_RS04395 f58ea028e8f3e9f84948d9875040e881 423 Gene3D G3DSA:3.30.559.10 42 152 2.1E-8 T 29-03-2018 MSG_RS19655 9706491ddfef7ac2dad6c06ea5a4a7c5 321 SUPERFAMILY SSF52266 72 269 2.6E-27 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS19655 9706491ddfef7ac2dad6c06ea5a4a7c5 321 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 76 255 2.8E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS19655 9706491ddfef7ac2dad6c06ea5a4a7c5 321 Gene3D G3DSA:3.40.50.1110 69 278 2.9E-24 T 29-03-2018 MSG_RS15135 cf62767870b91eb04f42e5ef7613ef5e 145 Pfam PF05423 Mycobacterium membrane protein 10 145 1.4E-40 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Gene3D G3DSA:3.40.50.980 165 320 3.7E-39 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Pfam PF00501 AMP-binding enzyme 40 406 6.2E-82 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Gene3D G3DSA:3.30.300.30 401 506 3.8E-23 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 SUPERFAMILY SSF56801 25 500 1.1E-125 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Gene3D G3DSA:3.40.50.980 30 135 7.1E-24 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Gene3D G3DSA:3.40.50.980 136 164 7.1E-7 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Gene3D G3DSA:2.30.38.10 321 399 2.5E-19 T 29-03-2018 MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS08720 76d5cf384d8b9c822408bcfb89d6d97e 507 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 490 1.7E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS05130 a61b7ed0f6eb2a5be065095b3a6ec22b 300 SUPERFAMILY SSF51197 6 280 2.06E-80 T 29-03-2018 MSG_RS05130 a61b7ed0f6eb2a5be065095b3a6ec22b 300 Gene3D G3DSA:3.60.130.10 1 291 1.1E-70 T 29-03-2018 MSG_RS05130 a61b7ed0f6eb2a5be065095b3a6ec22b 300 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 273 1.4E-50 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 ProSitePatterns PS01270 Band 7 protein family signature. 138 166 - T 29-03-2018 IPR018080 Band 7/stomatin-like, conserved site MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 158 176 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 177 198 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 31 53 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 114 131 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 79 100 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 PRINTS PR00721 Stomatin signature 134 157 4.1E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 SUPERFAMILY SSF117892 55 189 6.02E-39 T 29-03-2018 IPR001107 Band 7 domain MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 SMART SM00244 24 182 1.2E-55 T 29-03-2018 IPR001107 Band 7 domain MSG_RS10700 e5a97248d410edd9e490529ac5ac5611 381 Pfam PF01145 SPFH domain / Band 7 family 29 197 8.6E-30 T 29-03-2018 IPR001107 Band 7 domain MSG_RS16015 64483f6fd32564b37025c71b0e99eb38 265 Pfam PF12697 Alpha/beta hydrolase family 18 245 2.6E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS16015 64483f6fd32564b37025c71b0e99eb38 265 Gene3D G3DSA:3.40.50.1820 4 264 3.5E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16015 64483f6fd32564b37025c71b0e99eb38 265 SUPERFAMILY SSF53474 192 260 7.36E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16015 64483f6fd32564b37025c71b0e99eb38 265 SUPERFAMILY SSF53474 9 118 7.36E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 SUPERFAMILY SSF52540 204 408 2.36E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 ProSitePatterns PS00211 ABC transporters family signature. 334 348 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 Gene3D G3DSA:3.40.50.300 211 421 1.8E-39 T 29-03-2018 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 Gene3D G3DSA:3.40.50.300 436 648 5.8E-45 T 29-03-2018 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 Pfam PF00005 ABC transporter 457 594 3.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 Pfam PF00005 ABC transporter 228 362 1.1E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 SMART SM00382 466 643 1.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 SMART SM00382 237 444 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 Pfam PF09991 Predicted membrane protein (DUF2232) 3 185 4.7E-7 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 SUPERFAMILY SSF52540 435 645 1.92E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS16455 4414d763c1a5e3a4a5a72dbb94394b15 656 ProSitePatterns PS00211 ABC transporters family signature. 567 581 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS15320 d92d697f8547dac74bf96b96cf476c5a 213 Pfam PF10812 Protein of unknown function (DUF2561) 1 207 4.4E-92 T 29-03-2018 IPR024381 Protein of unknown function DUF2561 MSG_RS15320 d92d697f8547dac74bf96b96cf476c5a 213 Gene3D G3DSA:1.20.1250.20 20 205 7.6E-4 T 29-03-2018 MSG_RS15320 d92d697f8547dac74bf96b96cf476c5a 213 ProDom PD111926 TRANSMEMBRANE MEMBRANE RV2197C/MT2253 PROBABLE ML0878 1 207 2.0E-44 T 29-03-2018 IPR024381 Protein of unknown function DUF2561 MSG_RS13250 94330d89e30c281d46c8ee597ceaf2e6 376 SUPERFAMILY SSF51412 119 364 1.01E-47 T 29-03-2018 MSG_RS13250 94330d89e30c281d46c8ee597ceaf2e6 376 SUPERFAMILY SSF51412 1 70 1.01E-47 T 29-03-2018 MSG_RS13250 94330d89e30c281d46c8ee597ceaf2e6 376 Gene3D G3DSA:3.20.20.70 1 374 3.4E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS13250 94330d89e30c281d46c8ee597ceaf2e6 376 Pfam PF03060 Nitronate monooxygenase 21 310 3.7E-45 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Gene3D G3DSA:1.10.540.10 5 109 1.0E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 114 197 1.6E-19 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 110 7.9E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Gene3D G3DSA:2.40.110.10 110 207 5.7E-31 T 29-03-2018 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 378 1.2E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 Gene3D G3DSA:1.20.140.10 208 391 7.1E-33 T 29-03-2018 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 SUPERFAMILY SSF56645 12 233 1.31E-65 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS08740 e91e77d572c1190e667c5678a8f42b6d 397 SUPERFAMILY SSF47203 220 380 5.14E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS09490 bcb6d5f52255e40978db36078797c8eb 127 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 122 9.4E-29 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MSG_RS09490 bcb6d5f52255e40978db36078797c8eb 127 SUPERFAMILY SSF52091 21 126 3.53E-16 T 29-03-2018 IPR002645 STAS domain MSG_RS09490 bcb6d5f52255e40978db36078797c8eb 127 Pfam PF01740 STAS domain 22 124 1.8E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS09490 bcb6d5f52255e40978db36078797c8eb 127 Gene3D G3DSA:3.30.750.24 13 127 2.7E-15 T 29-03-2018 IPR002645 STAS domain MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 SUPERFAMILY SSF52402 154 276 1.0E-7 T 29-03-2018 MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 Gene3D G3DSA:3.40.50.620 3 142 1.9E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 PRINTS PR01438 Universal stress protein signature 11 29 1.0E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 PRINTS PR01438 Universal stress protein signature 120 142 1.0E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 PRINTS PR01438 Universal stress protein signature 102 114 1.0E-9 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 Pfam PF00582 Universal stress protein family 12 142 2.1E-15 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 SUPERFAMILY SSF52402 12 143 2.34E-17 T 29-03-2018 MSG_RS13950 181c4533111d8a50d7ef3f4dae5251e8 285 Gene3D G3DSA:3.40.50.620 146 279 3.5E-10 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 Gene3D G3DSA:1.10.357.10 90 186 1.2E-7 T 29-03-2018 MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 Gene3D G3DSA:1.10.260.40 43 89 1.4E-8 T 29-03-2018 MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.1E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 SUPERFAMILY SSF46689 10 71 2.74E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 SUPERFAMILY SSF48498 80 186 5.4E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS15765 6ab3eedd6fd7a585a3806027d329f85b 189 Gene3D G3DSA:1.10.10.60 12 42 7.9E-14 T 29-03-2018 MSG_RS05385 703085ac59acb96909f907f78c8898a3 269 Gene3D G3DSA:3.40.50.1820 1 254 2.3E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05385 703085ac59acb96909f907f78c8898a3 269 SUPERFAMILY SSF53474 1 253 3.82E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05385 703085ac59acb96909f907f78c8898a3 269 Pfam PF12697 Alpha/beta hydrolase family 1 245 9.2E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS04260 5fd8a84dc84a36b8306d383e7afd7663 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS04260 5fd8a84dc84a36b8306d383e7afd7663 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 205 4.9E-41 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS04260 5fd8a84dc84a36b8306d383e7afd7663 255 Gene3D G3DSA:3.90.226.10 1 249 2.4E-60 T 29-03-2018 MSG_RS04260 5fd8a84dc84a36b8306d383e7afd7663 255 SUPERFAMILY SSF52096 1 241 1.84E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04000 f2032e882606acb7017c983306a86665 161 Gene3D G3DSA:2.30.110.10 29 159 1.6E-11 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS04000 f2032e882606acb7017c983306a86665 161 PIRSF PIRSF021513 4 161 2.5E-70 T 29-03-2018 IPR016791 Rubromycin-type polyketide biosynthesis protein, GrhN/RubW, predicted MSG_RS21025 c220951f7a7e120ea632871227d9363a 248 Gene3D G3DSA:3.90.226.10 1 195 1.1E-56 T 29-03-2018 MSG_RS21025 c220951f7a7e120ea632871227d9363a 248 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 206 8.4E-45 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS21025 c220951f7a7e120ea632871227d9363a 248 SUPERFAMILY SSF52096 4 229 4.83E-56 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS21025 c220951f7a7e120ea632871227d9363a 248 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 Gene3D G3DSA:4.10.910.10 68 86 2.6E-16 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 PIRSF PIRSF002134 1 124 3.6E-45 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 SUPERFAMILY SSF46946 2 121 1.83E-46 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 5.7E-53 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 28.102 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-35 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 Gene3D G3DSA:1.10.8.50 1 67 3.5E-24 T 29-03-2018 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 Gene3D G3DSA:4.10.910.10 87 122 9.5E-26 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04830 85fa6127d3e0e652ec92b30942b925cc 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS00305 f9326eec4e62c5ce69fffe51706a895e 274 SUPERFAMILY SSF51679 11 220 1.91E-46 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00305 f9326eec4e62c5ce69fffe51706a895e 274 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 11 272 9.5E-133 T 29-03-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 MSG_RS00305 f9326eec4e62c5ce69fffe51706a895e 274 Pfam PF00296 Luciferase-like monooxygenase 16 219 7.3E-35 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00305 f9326eec4e62c5ce69fffe51706a895e 274 Gene3D G3DSA:3.20.20.30 2 228 8.1E-51 T 29-03-2018 MSG_RS21535 fe96e727e7cebed44d604cce0fb3cdf4 123 SUPERFAMILY SSF54292 31 121 3.41E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS21535 fe96e727e7cebed44d604cce0fb3cdf4 123 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 112 8.8E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS21535 fe96e727e7cebed44d604cce0fb3cdf4 123 Gene3D G3DSA:3.10.20.30 5 123 6.6E-28 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS21535 fe96e727e7cebed44d604cce0fb3cdf4 123 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 71 79 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 SUPERFAMILY SSF51905 17 401 3.46E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 191 216 1.9E-7 T 29-03-2018 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 1.9E-7 T 29-03-2018 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 Pfam PF00743 Flavin-binding monooxygenase-like 21 357 1.3E-17 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 Gene3D G3DSA:3.50.50.60 19 180 5.2E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03915 62c63047a3a56789a57ca99858a105dd 503 Gene3D G3DSA:3.50.50.60 181 469 4.6E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 Pfam PF12437 Glutamine synthetase type III N terminal 32 193 9.6E-75 T 29-03-2018 IPR022147 Glutamine synthetase type III N-terminal GO:0004356 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 SUPERFAMILY SSF55931 211 418 9.61E-74 T 29-03-2018 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 SUPERFAMILY SSF55931 461 607 9.61E-74 T 29-03-2018 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 Gene3D G3DSA:3.30.590.10 199 608 2.2E-83 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 Pfam PF00120 Glutamine synthetase, catalytic domain 201 400 1.2E-21 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 SMART SM01230 194 479 5.7E-51 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MSG_RS12035 15a7fff80e57356464558c2dadf61001 725 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 339 354 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MSG_RS14095 e065af3d8e54ec0df31fc9ade95f0de7 384 Gene3D G3DSA:3.40.50.1820 89 369 3.4E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14095 e065af3d8e54ec0df31fc9ade95f0de7 384 SUPERFAMILY SSF53474 304 367 1.99E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14095 e065af3d8e54ec0df31fc9ade95f0de7 384 SUPERFAMILY SSF53474 130 272 1.99E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24515 520eb328e15acaba19c92afd1a608aa5 524 SUPERFAMILY SSF52540 276 514 3.04E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24515 520eb328e15acaba19c92afd1a608aa5 524 Gene3D G3DSA:3.40.50.300 272 524 9.4E-29 T 29-03-2018 MSG_RS24515 520eb328e15acaba19c92afd1a608aa5 524 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 277 489 4.2E-12 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 SUPERFAMILY SSF51735 1 161 3.19E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 186 214 1.1E-9 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 281 317 1.3E-4 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 SMART SM01350 186 335 8.1E-5 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 Gene3D G3DSA:1.10.1040.10 188 338 1.2E-40 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 SUPERFAMILY SSF48179 184 334 1.77E-36 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 60 89 8.4E-20 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 113 138 8.4E-20 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 8.4E-20 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 338 1.1E-146 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 Gene3D G3DSA:3.40.50.720 1 187 3.7E-36 T 29-03-2018 MSG_RS19405 7ebf299d4f52c704a0213cfa7c5551b4 342 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 155 1.1E-40 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 236 3.6E-60 T 29-03-2018 MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 SUPERFAMILY SSF51735 4 239 6.58E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 8.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 Gene3D G3DSA:3.40.50.720 44 242 2.1E-59 T 29-03-2018 MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 Gene3D G3DSA:3.40.50.10090 2 43 4.0E-6 T 29-03-2018 MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.8E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01675 81818afee2de4ad82ca6c02268b8aadc 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS21580 db66d9243bba0a06010f0615335c724f 343 SUPERFAMILY SSF46548 153 305 7.85E-10 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MSG_RS21580 db66d9243bba0a06010f0615335c724f 343 Pfam PF00037 4Fe-4S binding domain 191 210 8.5E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS21580 db66d9243bba0a06010f0615335c724f 343 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS21580 db66d9243bba0a06010f0615335c724f 343 Gene3D G3DSA:3.30.70.20 204 337 3.8E-10 T 29-03-2018 MSG_RS21580 db66d9243bba0a06010f0615335c724f 343 Gene3D G3DSA:3.30.70.20 72 203 1.4E-5 T 29-03-2018 MSG_RS22115 64f403337f51a7bcc85b5d23da230fe3 279 Gene3D G3DSA:3.40.190.10 37 168 0.0017 T 29-03-2018 MSG_RS18855 39f87baf40aab93103b239da8b190d3e 193 SUPERFAMILY SSF48150 7 189 4.4E-66 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS18855 39f87baf40aab93103b239da8b190d3e 193 Pfam PF03352 Methyladenine glycosylase 21 187 3.7E-67 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MSG_RS18855 39f87baf40aab93103b239da8b190d3e 193 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 7 189 7.9E-89 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 MSG_RS18855 39f87baf40aab93103b239da8b190d3e 193 Gene3D G3DSA:1.10.340.30 6 189 5.8E-74 T 29-03-2018 MSG_RS16500 a9dcb91edf2f8fb9796a91d10cb247db 196 Pfam PF11127 Protein of unknown function (DUF2892) 119 171 9.0E-8 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 MSG_RS16500 a9dcb91edf2f8fb9796a91d10cb247db 196 SUPERFAMILY SSF52821 7 114 7.07E-27 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16500 a9dcb91edf2f8fb9796a91d10cb247db 196 Pfam PF00581 Rhodanese-like domain 13 104 2.7E-14 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16500 a9dcb91edf2f8fb9796a91d10cb247db 196 SMART SM00450 10 109 1.2E-21 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS16500 a9dcb91edf2f8fb9796a91d10cb247db 196 Gene3D G3DSA:3.40.250.10 1 118 1.3E-27 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 Pfam PF03841 L-seryl-tRNA selenium transferase 74 415 4.9E-103 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 8 428 1.1E-130 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 SUPERFAMILY SSF53383 70 431 5.48E-36 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 Pfam PF12390 Selenocysteine synthase N terminal 7 46 1.5E-6 T 29-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 433 172.89 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MSG_RS00735 351badc4c72fcf219c654d9214c3e14b 439 Gene3D G3DSA:3.40.640.10 31 336 4.8E-28 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS09630 8070a420884c370260dcac418105c15e 251 Gene3D G3DSA:1.10.10.200 1 78 5.7E-29 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like MSG_RS09630 8070a420884c370260dcac418105c15e 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.6E-99 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS09630 8070a420884c370260dcac418105c15e 251 Gene3D G3DSA:3.30.70.980 179 249 6.4E-12 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS09630 8070a420884c370260dcac418105c15e 251 Pfam PF01709 Transcriptional regulator 5 238 5.2E-90 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS09630 8070a420884c370260dcac418105c15e 251 Gene3D G3DSA:3.30.70.980 84 178 2.5E-29 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS09630 8070a420884c370260dcac418105c15e 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.583 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS09630 8070a420884c370260dcac418105c15e 251 SUPERFAMILY SSF75625 3 246 1.96E-89 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS07265 e6d5ef2f98548d91039462f0f6ef9b91 151 Gene3D G3DSA:2.40.50.140 75 137 4.7E-17 T 29-03-2018 MSG_RS07265 e6d5ef2f98548d91039462f0f6ef9b91 151 SUPERFAMILY SSF50249 43 137 6.34E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS07265 e6d5ef2f98548d91039462f0f6ef9b91 151 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 135 1.1E-20 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 SMART SM00829 13 335 1.8E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 Gene3D G3DSA:3.40.50.720 151 330 2.6E-30 T 29-03-2018 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 SUPERFAMILY SSF51735 140 300 1.93E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 Pfam PF00107 Zinc-binding dehydrogenase 177 300 4.9E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 Gene3D G3DSA:3.90.180.10 1 150 2.9E-44 T 29-03-2018 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 134 7.6E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS13225 7068e9bf0e0a2cfc3de0c6d58207da8c 337 SUPERFAMILY SSF50129 6 165 6.92E-48 T 29-03-2018 IPR011032 GroES-like MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 Pfam PF08343 Ribonucleotide reductase N-terminal 24 105 2.5E-31 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 111 704 5.5E-158 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 Gene3D G3DSA:3.20.70.20 87 709 1.1E-161 T 29-03-2018 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 107 179 7.1E-12 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 SUPERFAMILY SSF48168 22 182 2.22E-61 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 Pfam PF02867 Ribonucleotide reductase, barrel domain 184 701 5.0E-144 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 585 612 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 259 278 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 501 524 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 495 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 390 401 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 PRINTS PR01183 Ribonucleotide reductase large chain signature 434 457 4.8E-33 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 SUPERFAMILY SSF51998 183 706 1.83E-186 T 29-03-2018 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 574 596 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MSG_RS07350 a1cfd6ea23c4e1d963c87479076956db 722 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 23 722 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MSG_RS04870 9aa5803f8f7879fd45d7dfb238e439e7 463 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 448 1.6E-135 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS04870 9aa5803f8f7879fd45d7dfb238e439e7 463 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 5 460 1.5E-140 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS20790 37530214b521c9295134fd80503dcc25 359 SMART SM00729 38 243 3.0E-11 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 Gene3D G3DSA:3.20.20.70 25 359 5.0E-77 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 29 359 38.809 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 44 55 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 Pfam PF04055 Radical SAM superfamily 43 204 1.5E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 Pfam PF13353 4Fe-4S single cluster domain 45 123 8.0E-5 T 29-03-2018 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 Pfam PF06463 Molybdenum Cofactor Synthesis C 210 341 4.9E-34 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 SUPERFAMILY SSF102114 28 307 1.14E-66 T 29-03-2018 MSG_RS20790 37530214b521c9295134fd80503dcc25 359 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 29 359 3.6E-108 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MSG_RS04800 b00df8b6084c8c1086855523fb24a18b 288 Gene3D G3DSA:3.20.20.30 115 280 1.7E-12 T 29-03-2018 MSG_RS04800 b00df8b6084c8c1086855523fb24a18b 288 SUPERFAMILY SSF51679 23 279 4.84E-36 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04800 b00df8b6084c8c1086855523fb24a18b 288 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 11 281 7.8E-114 T 29-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted MSG_RS04800 b00df8b6084c8c1086855523fb24a18b 288 Gene3D G3DSA:3.20.20.30 23 114 5.0E-13 T 29-03-2018 MSG_RS04800 b00df8b6084c8c1086855523fb24a18b 288 Pfam PF00296 Luciferase-like monooxygenase 25 257 2.0E-11 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 Pfam PF00069 Protein kinase domain 12 214 6.3E-25 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 SMART SM00220 12 258 3.5E-17 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 Gene3D G3DSA:1.10.510.10 81 448 6.2E-29 T 29-03-2018 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 Gene3D G3DSA:3.30.200.20 7 80 1.2E-13 T 29-03-2018 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS08160 598ff7dc9c448cfe9ebccdd98611d34f 575 SUPERFAMILY SSF56112 11 259 3.78E-45 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 Gene3D G3DSA:1.20.1250.20 38 229 8.4E-28 T 29-03-2018 MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 Gene3D G3DSA:1.20.1250.20 288 536 2.4E-29 T 29-03-2018 MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 SUPERFAMILY SSF103473 39 222 3.92E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 SUPERFAMILY SSF103473 277 450 3.92E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 SUPERFAMILY SSF103473 501 529 3.92E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 Pfam PF07690 Major Facilitator Superfamily 46 440 4.6E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS21935 bca92f96d58e7fc554842da456782f22 543 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 40 524 2.1E-146 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MSG_RS23465 8c24f505f0cb572ca868c7c969a49502 420 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 149 413 2.2E-4 T 29-03-2018 IPR020803 Polyketide synthase, methyltransferase domain MSG_RS23465 8c24f505f0cb572ca868c7c969a49502 420 Pfam PF02353 Mycolic acid cyclopropane synthetase 130 398 3.8E-100 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23465 8c24f505f0cb572ca868c7c969a49502 420 Gene3D G3DSA:3.40.50.150 128 403 4.9E-61 T 29-03-2018 MSG_RS23465 8c24f505f0cb572ca868c7c969a49502 420 PIRSF PIRSF003085 2 420 6.7E-127 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS23465 8c24f505f0cb572ca868c7c969a49502 420 SUPERFAMILY SSF53335 141 401 1.02E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS22260 351eda32c491c515077d615ab1085998 388 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 305 4.4E-74 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22260 351eda32c491c515077d615ab1085998 388 Pfam PF02470 MlaD protein 43 119 4.8E-10 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS08390 8923cf6093ce6ee6c1ccafda792e7ef8 220 Gene3D G3DSA:2.30.180.10 84 217 2.3E-27 T 29-03-2018 IPR000782 FAS1 domain MSG_RS08390 8923cf6093ce6ee6c1ccafda792e7ef8 220 SMART SM00554 124 219 6.4E-29 T 29-03-2018 IPR000782 FAS1 domain MSG_RS08390 8923cf6093ce6ee6c1ccafda792e7ef8 220 SUPERFAMILY SSF82153 65 219 1.26E-35 T 29-03-2018 IPR000782 FAS1 domain MSG_RS08390 8923cf6093ce6ee6c1ccafda792e7ef8 220 Pfam PF02469 Fasciclin domain 96 218 1.2E-25 T 29-03-2018 IPR000782 FAS1 domain MSG_RS23585 a44e7022ed69d982f053bae1e0c77958 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 178 1.8E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS23585 a44e7022ed69d982f053bae1e0c77958 327 Gene3D G3DSA:3.40.50.720 1 327 1.5E-49 T 29-03-2018 MSG_RS23585 a44e7022ed69d982f053bae1e0c77958 327 SUPERFAMILY SSF51735 1 323 4.98E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15980 eadb85bd7f349fedbc361d869cd349e3 391 SUPERFAMILY SSF52540 256 354 1.96E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS15980 eadb85bd7f349fedbc361d869cd349e3 391 SUPERFAMILY SSF52540 1 177 1.96E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS15980 eadb85bd7f349fedbc361d869cd349e3 391 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 345 1.0E-25 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MSG_RS15980 eadb85bd7f349fedbc361d869cd349e3 391 PIRSF PIRSF029347 1 391 1.4E-129 T 29-03-2018 IPR014555 RecF-like MSG_RS15980 eadb85bd7f349fedbc361d869cd349e3 391 Gene3D G3DSA:3.40.50.300 1 356 6.5E-27 T 29-03-2018 MSG_RS21745 df628569d70994a75670f2201670cd15 516 Pfam PF14032 PknH-like extracellular domain 328 513 8.4E-41 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS21745 df628569d70994a75670f2201670cd15 516 SUPERFAMILY SSF52200 3 98 3.01E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS21745 df628569d70994a75670f2201670cd15 516 Gene3D G3DSA:3.40.50.10140 2 128 5.1E-19 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS21745 df628569d70994a75670f2201670cd15 516 Pfam PF13676 TIR domain 4 102 2.8E-23 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS09715 b667496cc1f8d9e5bea4a5479ed05b13 194 Pfam PF00156 Phosphoribosyl transferase domain 51 173 2.9E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS09715 b667496cc1f8d9e5bea4a5479ed05b13 194 Gene3D G3DSA:3.40.50.2020 25 193 8.1E-39 T 29-03-2018 MSG_RS09715 b667496cc1f8d9e5bea4a5479ed05b13 194 SUPERFAMILY SSF53271 33 189 8.52E-40 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS09715 b667496cc1f8d9e5bea4a5479ed05b13 194 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 28 194 33.002 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MSG_RS19980 eff5e34ec103a7598e51dcd5a5ce7ef4 186 Gene3D G3DSA:2.60.120.10 1 183 9.8E-55 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS19980 eff5e34ec103a7598e51dcd5a5ce7ef4 186 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 173 1.0E-71 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS19980 eff5e34ec103a7598e51dcd5a5ce7ef4 186 SUPERFAMILY SSF51182 2 173 6.71E-58 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS19980 eff5e34ec103a7598e51dcd5a5ce7ef4 186 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 173 8.0E-55 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS19340 053b1aa36942166801ce2c225ae51d72 453 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 3 96 9.0E-27 T 29-03-2018 MSG_RS19340 053b1aa36942166801ce2c225ae51d72 453 Pfam PF02720 Domain of unknown function (DUF222) 39 360 1.6E-99 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS19340 053b1aa36942166801ce2c225ae51d72 453 Gene3D G3DSA:3.40.1800.10 343 408 6.9E-4 T 29-03-2018 MSG_RS19340 053b1aa36942166801ce2c225ae51d72 453 SMART SM00507 351 404 4.3E-6 T 29-03-2018 IPR003615 HNH nuclease MSG_RS11190 083ed5922037686cc58c2a9ff61a652d 117 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 2.0E-24 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MSG_RS11190 083ed5922037686cc58c2a9ff61a652d 117 SUPERFAMILY SSF141734 6 110 6.93E-45 T 29-03-2018 MSG_RS11190 083ed5922037686cc58c2a9ff61a652d 117 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 30.873 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MSG_RS11190 083ed5922037686cc58c2a9ff61a652d 117 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 2.9E-33 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MSG_RS05275 77333d8c547373a0e42f9e9ea1599619 124 Gene3D G3DSA:1.10.10.10 3 121 1.7E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05275 77333d8c547373a0e42f9e9ea1599619 124 Pfam PF05331 Protein of unknown function (DUF742) 11 124 1.4E-31 T 29-03-2018 IPR007995 Protein of unknown function DUF742 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 155 171 4.2E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 75 83 4.2E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 117 132 4.2E-16 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 Pfam PF01252 Signal peptidase (SPase) II 37 174 4.9E-31 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 ProSitePatterns PS00855 Signal peptidases II signature. 120 132 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 TIGRFAM TIGR00077 lspA: signal peptidase II 29 175 1.4E-27 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS10955 3e76d8abf4cc4b99b00824a6980da9d5 190 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 28 180 15.467 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 SUPERFAMILY SSF47648 78 144 5.89E-17 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 SUPERFAMILY SSF52418 149 417 5.36E-80 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 Pfam PF02885 Glycosyl transferase family, helical bundle domain 81 141 2.2E-16 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 80 415 34.421 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 Pfam PF00591 Glycosyl transferase family, a/b domain 149 405 1.1E-90 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 Gene3D G3DSA:3.40.1030.10 147 419 1.4E-98 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 83 414 5.8E-118 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MSG_RS15290 cb994cfd54b96862738386a0548d4210 419 Gene3D G3DSA:1.20.970.10 72 145 6.5E-20 T 29-03-2018 MSG_RS01095 23dde48f2e3c620ff91f1884241baa88 159 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 16 139 8.0E-7 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS01095 23dde48f2e3c620ff91f1884241baa88 159 Gene3D G3DSA:3.30.530.20 12 159 1.5E-12 T 29-03-2018 IPR023393 START-like domain MSG_RS01095 23dde48f2e3c620ff91f1884241baa88 159 SUPERFAMILY SSF55961 13 134 8.39E-13 T 29-03-2018 MSG_RS22685 908cf1cc93f47ae44267ac7f5b46e4f2 252 SUPERFAMILY SSF88713 3 251 2.22E-95 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS22685 908cf1cc93f47ae44267ac7f5b46e4f2 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 44.089 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF MSG_RS22685 908cf1cc93f47ae44267ac7f5b46e4f2 252 Gene3D G3DSA:3.20.20.370 3 250 4.3E-103 T 29-03-2018 MSG_RS22685 908cf1cc93f47ae44267ac7f5b46e4f2 252 Pfam PF03746 LamB/YcsF family 4 241 1.7E-98 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF MSG_RS17600 c13e235e1d6870331756411f2a79a3c5 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 261 8.6E-12 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS17600 c13e235e1d6870331756411f2a79a3c5 265 Gene3D G3DSA:3.90.850.10 5 265 2.7E-47 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS17600 c13e235e1d6870331756411f2a79a3c5 265 SUPERFAMILY SSF56529 10 264 5.76E-70 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS24185 6b7da306ecc2855c2a2d75efa3eb6db6 346 SUPERFAMILY SSF53474 44 327 3.96E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24185 6b7da306ecc2855c2a2d75efa3eb6db6 346 Pfam PF00756 Putative esterase 58 321 1.7E-71 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS24185 6b7da306ecc2855c2a2d75efa3eb6db6 346 Gene3D G3DSA:3.40.50.1820 42 327 2.7E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 SUPERFAMILY SSF48498 88 199 3.56E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 SUPERFAMILY SSF46689 14 75 1.23E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 Gene3D G3DSA:1.10.10.60 15 76 3.2E-14 T 29-03-2018 MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 Gene3D G3DSA:1.10.357.10 77 203 8.2E-18 T 29-03-2018 MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 66 1.1E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS24415 96101d7f9d1860aa6e96aaa031aecf5c 203 Pfam PF16925 Bacterial transcriptional repressor C-terminal 109 195 2.8E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 84 8.5E-10 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 SMART SM00829 7 321 4.1E-32 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 323 4.0E-132 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 Pfam PF00107 Zinc-binding dehydrogenase 148 261 1.0E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 Gene3D G3DSA:3.40.50.720 130 307 2.2E-37 T 29-03-2018 MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 SUPERFAMILY SSF50129 1 135 4.25E-33 T 29-03-2018 IPR011032 GroES-like MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 SUPERFAMILY SSF51735 108 264 1.88E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24020 936d4fea8b72df59558ebdd85c400507 323 Gene3D G3DSA:3.90.180.10 1 129 4.3E-33 T 29-03-2018 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 SUPERFAMILY SSF82866 471 702 5.89E-26 T 29-03-2018 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 SUPERFAMILY SSF82866 154 336 1.02E-28 T 29-03-2018 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 Gene3D G3DSA:1.20.1640.10 120 343 4.0E-28 T 29-03-2018 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 Gene3D G3DSA:1.20.1640.10 477 701 4.1E-30 T 29-03-2018 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 Pfam PF03176 MMPL family 117 369 2.2E-40 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS01905 8a95f93d3e437c416137889b063f32e0 1015 Pfam PF03176 MMPL family 451 705 7.5E-37 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 Gene3D G3DSA:3.40.1700.10 3 138 2.6E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 21 134 2.1E-25 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 1 354 42.458 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 SUPERFAMILY SSF143597 14 138 1.96E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 Pfam PF10635 DisA bacterial checkpoint controller linker region 139 280 1.2E-45 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 Gene3D G3DSA:1.10.150.20 290 354 1.7E-7 T 29-03-2018 MSG_RS22750 983bc54b73007e9b21f3c915727075d0 357 SUPERFAMILY SSF47781 286 346 5.93E-10 T 29-03-2018 IPR010994 RuvA domain 2-like MSG_RS08100 bca38d185ce883f7ddada897b94c7ddf 141 Gene3D G3DSA:3.30.300.20 2 138 3.6E-22 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS08100 bca38d185ce883f7ddada897b94c7ddf 141 Pfam PF02566 OsmC-like protein 34 130 7.4E-9 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS08100 bca38d185ce883f7ddada897b94c7ddf 141 SUPERFAMILY SSF82784 3 132 2.22E-19 T 29-03-2018 IPR003718 OsmC/Ohr family MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 SUPERFAMILY SSF47203 253 410 1.42E-36 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Gene3D G3DSA:2.40.110.10 145 243 1.2E-34 T 29-03-2018 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 228 2.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 405 2.4E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Gene3D G3DSA:1.10.540.10 13 144 3.9E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 141 5.9E-17 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 Gene3D G3DSA:1.20.140.10 244 416 1.3E-35 T 29-03-2018 MSG_RS01295 4687356e5cca2ce726756a1635c3c0cd 443 SUPERFAMILY SSF56645 14 267 1.18E-66 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS21235 8764c367388db32466b5650e96574464 297 SUPERFAMILY SSF53474 9 127 8.59E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21235 8764c367388db32466b5650e96574464 297 SUPERFAMILY SSF53474 176 281 8.59E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21235 8764c367388db32466b5650e96574464 297 Pfam PF12697 Alpha/beta hydrolase family 32 269 1.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS21235 8764c367388db32466b5650e96574464 297 Gene3D G3DSA:3.40.50.1820 13 282 2.8E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS07340 183c089ad689f1bd9d80174e069768a8 79 Gene3D G3DSA:3.40.30.10 1 79 2.2E-14 T 29-03-2018 MSG_RS07340 183c089ad689f1bd9d80174e069768a8 79 SUPERFAMILY SSF52833 1 72 1.32E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS07340 183c089ad689f1bd9d80174e069768a8 79 Pfam PF00462 Glutaredoxin 3 61 8.9E-15 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MSG_RS07340 183c089ad689f1bd9d80174e069768a8 79 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 6.6E-34 T 29-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 MSG_RS00225 f41697542c9b6ca3578c62106f3a21ec 496 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 466 2.3E-140 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS00225 f41697542c9b6ca3578c62106f3a21ec 496 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 480 4.8E-145 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 SUPERFAMILY SSF48264 20 411 3.14E-84 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 144 160 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 358 367 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 292 303 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 309 336 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 337 352 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 98 109 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 161 176 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 208 230 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 PRINTS PR00359 B-class P450 signature 367 378 4.2E-47 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 Pfam PF00067 Cytochrome P450 221 388 4.6E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 Gene3D G3DSA:1.10.630.10 6 415 2.0E-66 T 29-03-2018 MSG_RS21955 4971c675c18c7aaf406148cbbcfeadd8 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS07540 3d447043b2c7101eeeef0bef172c4f2b 168 Pfam PF12802 MarR family 41 101 8.3E-11 T 29-03-2018 MSG_RS07540 3d447043b2c7101eeeef0bef172c4f2b 168 SMART SM00347 34 137 0.0035 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS07540 3d447043b2c7101eeeef0bef172c4f2b 168 SUPERFAMILY SSF46785 27 150 7.45E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS07540 3d447043b2c7101eeeef0bef172c4f2b 168 Gene3D G3DSA:1.10.10.10 2 154 1.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01790 b7ac51b7f757d26ee7d9da05dc9467a8 241 Pfam PF02678 Pirin 12 122 3.6E-37 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MSG_RS01790 b7ac51b7f757d26ee7d9da05dc9467a8 241 SUPERFAMILY SSF51182 7 235 2.32E-63 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS01790 b7ac51b7f757d26ee7d9da05dc9467a8 241 Gene3D G3DSA:2.60.120.10 135 238 8.2E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS01790 b7ac51b7f757d26ee7d9da05dc9467a8 241 PIRSF PIRSF006232 3 236 2.2E-50 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MSG_RS01790 b7ac51b7f757d26ee7d9da05dc9467a8 241 Gene3D G3DSA:2.60.120.10 15 134 1.6E-45 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS07070 70a44c804e8bdc1b4ce0bb74ea264493 122 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 7 120 16.591 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MSG_RS07070 70a44c804e8bdc1b4ce0bb74ea264493 122 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 10 115 3.5E-21 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 SMART SM00220 16 276 4.1E-52 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 Gene3D G3DSA:1.10.510.10 112 298 1.2E-44 T 29-03-2018 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 Gene3D G3DSA:3.30.200.20 7 111 1.6E-20 T 29-03-2018 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 SUPERFAMILY SSF56112 13 343 2.02E-72 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS18560 767b09dfee863b501650aab99114dafb 605 Pfam PF14032 PknH-like extracellular domain 414 601 4.9E-48 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS18560 767b09dfee863b501650aab99114dafb 605 Pfam PF00069 Protein kinase domain 16 262 2.5E-43 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 Gene3D G3DSA:1.10.10.10 14 88 1.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 Pfam PF09339 IclR helix-turn-helix domain 23 70 5.4E-10 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 SUPERFAMILY SSF46785 22 87 3.04E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 Gene3D G3DSA:3.30.450.40 90 167 2.2E-18 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 Gene3D G3DSA:3.30.450.40 172 238 8.3E-4 T 29-03-2018 IPR029016 GAF domain-like MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 SMART SM00346 20 108 3.1E-5 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS00495 b9aa11c247d4208a8f2b06e05dd7a9d7 238 SUPERFAMILY SSF55781 76 235 1.96E-20 T 29-03-2018 IPR029016 GAF domain-like MSG_RS06655 b0c177dd6ed8510af4bdf31807ac264b 378 SUPERFAMILY SSF56112 30 333 7.82E-33 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS06655 b0c177dd6ed8510af4bdf31807ac264b 378 Pfam PF01636 Phosphotransferase enzyme family 74 287 7.1E-20 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS06655 b0c177dd6ed8510af4bdf31807ac264b 378 Gene3D G3DSA:3.90.1200.10 156 356 3.5E-15 T 29-03-2018 MSG_RS06655 b0c177dd6ed8510af4bdf31807ac264b 378 Gene3D G3DSA:3.30.200.20 24 136 1.1E-16 T 29-03-2018 MSG_RS15070 a16331f69ab5ef3b00a8c35f17724fbf 256 SUPERFAMILY SSF64438 25 256 2.75E-76 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MSG_RS15070 a16331f69ab5ef3b00a8c35f17724fbf 256 Gene3D G3DSA:3.60.140.10 12 256 1.2E-86 T 29-03-2018 MSG_RS15070 a16331f69ab5ef3b00a8c35f17724fbf 256 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 31 254 2.3E-73 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MSG_RS15070 a16331f69ab5ef3b00a8c35f17724fbf 256 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 36 256 3.1E-65 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MSG_RS15040 4841706e913f8870d3bf0bd91680be98 225 Gene3D G3DSA:3.40.50.2020 2 224 1.3E-36 T 29-03-2018 MSG_RS15040 4841706e913f8870d3bf0bd91680be98 225 Pfam PF00156 Phosphoribosyl transferase domain 22 208 4.8E-21 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS15040 4841706e913f8870d3bf0bd91680be98 225 SUPERFAMILY SSF53271 15 221 3.41E-48 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS21700 3861ea3aae63d777cfdbb683037ef18f 255 SUPERFAMILY SSF46894 123 218 1.3E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS21700 3861ea3aae63d777cfdbb683037ef18f 255 Gene3D G3DSA:1.10.10.10 112 225 1.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS21700 3861ea3aae63d777cfdbb683037ef18f 255 SMART SM00862 145 219 7.0E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS21700 3861ea3aae63d777cfdbb683037ef18f 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.4E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS04900 648f4d332ca6669a9da29ab0405c3ae3 98 SUPERFAMILY SSF140453 4 96 5.75E-21 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS04900 648f4d332ca6669a9da29ab0405c3ae3 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.5E-21 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS04900 648f4d332ca6669a9da29ab0405c3ae3 98 Gene3D G3DSA:1.10.287.1060 2 98 1.1E-15 T 29-03-2018 MSG_RS04900 648f4d332ca6669a9da29ab0405c3ae3 98 Pfam PF06013 Proteins of 100 residues with WXG 6 90 6.0E-10 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS17550 0514fcd3b14bd6c17e5da200538db772 242 SMART SM00382 31 213 1.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS17550 0514fcd3b14bd6c17e5da200538db772 242 SUPERFAMILY SSF52540 9 224 7.14E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS17550 0514fcd3b14bd6c17e5da200538db772 242 Gene3D G3DSA:3.40.50.300 1 232 2.0E-58 T 29-03-2018 MSG_RS17550 0514fcd3b14bd6c17e5da200538db772 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS17550 0514fcd3b14bd6c17e5da200538db772 242 Pfam PF00005 ABC transporter 23 164 4.7E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 Gene3D G3DSA:2.40.50.140 1 124 7.5E-63 T 29-03-2018 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.567 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 SUPERFAMILY SSF50249 2 123 6.51E-52 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.6E-58 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.4E-42 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.8E-67 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04280 be3eefca7e3c563c96d60f431a88420c 124 PIRSF PIRSF002133 1 124 5.9E-54 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 Pfam PF01614 Bacterial transcriptional regulator 128 248 2.3E-32 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 SUPERFAMILY SSF46785 13 86 2.92E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 SMART SM00419 23 75 1.2E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 SMART SM00346 13 101 1.1E-29 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 Gene3D G3DSA:1.10.10.10 12 76 2.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 SUPERFAMILY SSF55781 71 251 3.79E-41 T 29-03-2018 IPR029016 GAF domain-like MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 Pfam PF09339 IclR helix-turn-helix domain 16 63 5.1E-12 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MSG_RS11795 11986d507b2fb1bf6affdcebde6fe8a3 257 Gene3D G3DSA:3.30.450.40 77 253 1.4E-40 T 29-03-2018 IPR029016 GAF domain-like MSG_RS21120 c0d43e4a2832f71c000ea1110e4f8aaa 425 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 173 395 8.3E-54 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS21120 c0d43e4a2832f71c000ea1110e4f8aaa 425 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 41 319 3.4E-65 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS21120 c0d43e4a2832f71c000ea1110e4f8aaa 425 Pfam PF02470 MlaD protein 66 144 1.5E-12 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS15960 fe15e7fa0a8f02a536a174a8e792276c 232 Pfam PF01323 DSBA-like thioredoxin domain 5 157 3.2E-12 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 MSG_RS15960 fe15e7fa0a8f02a536a174a8e792276c 232 Gene3D G3DSA:3.40.30.10 3 60 8.2E-9 T 29-03-2018 MSG_RS15960 fe15e7fa0a8f02a536a174a8e792276c 232 Gene3D G3DSA:3.40.30.10 61 162 8.4E-14 T 29-03-2018 MSG_RS15960 fe15e7fa0a8f02a536a174a8e792276c 232 SUPERFAMILY SSF52833 1 159 7.58E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS09560 d1dfa97577e998ca12104dc63cf09a7f 167 PIRSF PIRSF010260 1 167 4.7E-60 T 29-03-2018 IPR014457 Uncharacterised conserved protein UCP010260 MSG_RS09560 d1dfa97577e998ca12104dc63cf09a7f 167 Pfam PF09348 Domain of unknown function (DUF1990) 12 166 2.3E-54 T 29-03-2018 IPR018960 Domain of unknown function DUF1990 MSG_RS09010 780304f3dbc21b68488003d35e3ef3b0 82 Pfam PF11238 Protein of unknown function (DUF3039) 24 79 2.5E-27 T 29-03-2018 IPR021400 Protein of unknown function DUF3039 MSG_RS21195 2391a9408ffe8a489d24a3e0e441f5c2 363 Gene3D G3DSA:3.20.20.140 2 354 5.0E-43 T 29-03-2018 MSG_RS21195 2391a9408ffe8a489d24a3e0e441f5c2 363 Pfam PF04909 Amidohydrolase 14 354 1.7E-24 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS21195 2391a9408ffe8a489d24a3e0e441f5c2 363 SUPERFAMILY SSF51556 10 355 2.76E-53 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS15465 bac6d91871af40ea2a6a80757a3f83dc 312 Pfam PF13676 TIR domain 4 91 5.0E-23 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS15465 bac6d91871af40ea2a6a80757a3f83dc 312 SUPERFAMILY SSF52200 3 98 2.35E-17 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS15465 bac6d91871af40ea2a6a80757a3f83dc 312 Gene3D G3DSA:3.40.50.10140 2 212 9.1E-18 T 29-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 MSG_RS21205 b8d579d9ca5384c0d1a2e41971e8a51a 132 Pfam PF00355 Rieske [2Fe-2S] domain 19 113 3.8E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21205 b8d579d9ca5384c0d1a2e41971e8a51a 132 SUPERFAMILY SSF50022 18 131 7.33E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS21205 b8d579d9ca5384c0d1a2e41971e8a51a 132 Gene3D G3DSA:2.102.10.10 1 132 5.0E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 2.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 SUPERFAMILY SSF48498 90 204 1.29E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS01500 3980890381a281aa79e8113a9056c741 211 SUPERFAMILY SSF46689 11 93 6.67E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 Gene3D G3DSA:1.10.357.10 69 211 3.4E-13 T 29-03-2018 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 Gene3D G3DSA:1.10.10.60 1 68 1.1E-17 T 29-03-2018 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01500 3980890381a281aa79e8113a9056c741 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.4E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02615 bb40ccdc2994d5c9c6b5f3efef9f759a 190 Pfam PF00692 dUTPase 69 178 4.8E-11 T 29-03-2018 IPR029054 dUTPase-like MSG_RS02615 bb40ccdc2994d5c9c6b5f3efef9f759a 190 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 3.6E-64 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MSG_RS02615 bb40ccdc2994d5c9c6b5f3efef9f759a 190 SUPERFAMILY SSF51283 2 184 1.44E-55 T 29-03-2018 IPR029054 dUTPase-like MSG_RS02615 bb40ccdc2994d5c9c6b5f3efef9f759a 190 Gene3D G3DSA:2.70.40.10 1 159 3.9E-47 T 29-03-2018 MSG_RS02615 bb40ccdc2994d5c9c6b5f3efef9f759a 190 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.293 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MSG_RS19235 50a2e49bc32096a56ead2bdc175ac43a 240 Pfam PF02517 CAAX protease self-immunity 143 227 1.2E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 SUPERFAMILY SSF54637 165 276 1.01E-22 T 29-03-2018 IPR029069 HotDog domain MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 SUPERFAMILY SSF54637 25 147 4.32E-10 T 29-03-2018 IPR029069 HotDog domain MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 PRINTS PR01483 Fatty acid synthase signature 200 221 4.1E-9 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 PRINTS PR01483 Fatty acid synthase signature 178 200 4.1E-9 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 Gene3D G3DSA:3.10.129.10 164 262 3.9E-20 T 29-03-2018 MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 Pfam PF01575 MaoC like domain 162 253 4.4E-23 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS02165 faff95f1772960a7901e86ec6e5c54c7 280 Gene3D G3DSA:3.10.129.10 32 163 3.0E-23 T 29-03-2018 MSG_RS08750 a4404d65616723520d0f7e3c60ce8324 406 Gene3D G3DSA:3.40.50.2000 1 245 5.9E-38 T 29-03-2018 MSG_RS08750 a4404d65616723520d0f7e3c60ce8324 406 Gene3D G3DSA:3.40.50.2000 246 392 5.4E-32 T 29-03-2018 MSG_RS08750 a4404d65616723520d0f7e3c60ce8324 406 SUPERFAMILY SSF53756 1 404 1.18E-78 T 29-03-2018 MSG_RS16640 a29a60c6678c1f37f509057066710a9b 655 Gene3D G3DSA:1.20.5.50 226 357 0.14 T 29-03-2018 MSG_RS16640 a29a60c6678c1f37f509057066710a9b 655 Pfam PF04536 TPM domain 36 153 7.4E-18 T 29-03-2018 IPR007621 TPM domain MSG_RS16640 a29a60c6678c1f37f509057066710a9b 655 Gene3D G3DSA:1.20.1480.30 358 460 0.039 T 29-03-2018 MSG_RS03885 5817a353fdcb100e45e2d96904f9bd2e 335 Gene3D G3DSA:1.10.600.10 8 335 1.5E-93 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS03885 5817a353fdcb100e45e2d96904f9bd2e 335 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MSG_RS03885 5817a353fdcb100e45e2d96904f9bd2e 335 SUPERFAMILY SSF48576 20 334 5.37E-80 T 29-03-2018 IPR008949 Isoprenoid synthase domain MSG_RS03885 5817a353fdcb100e45e2d96904f9bd2e 335 Pfam PF00348 Polyprenyl synthetase 44 285 5.7E-62 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MSG_RS20380 c99c6a7694a70e3b91507d8b87059dc9 207 SUPERFAMILY SSF46689 12 86 8.21E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS20380 c99c6a7694a70e3b91507d8b87059dc9 207 Gene3D G3DSA:1.10.357.10 10 199 4.4E-26 T 29-03-2018 MSG_RS20380 c99c6a7694a70e3b91507d8b87059dc9 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09175 db7be5eac366cfafad9fc3469a67f190 163 Pfam PF01638 HxlR-like helix-turn-helix 19 107 2.0E-21 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS09175 db7be5eac366cfafad9fc3469a67f190 163 Gene3D G3DSA:1.10.10.10 1 157 3.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS09175 db7be5eac366cfafad9fc3469a67f190 163 SUPERFAMILY SSF46785 6 143 3.63E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17270 1a80644b8e8b5cd68600fa00bf145317 220 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 38 216 2.0E-34 T 29-03-2018 MSG_RS17270 1a80644b8e8b5cd68600fa00bf145317 220 Pfam PF13529 Peptidase_C39 like family 52 186 3.2E-5 T 29-03-2018 MSG_RS17270 1a80644b8e8b5cd68600fa00bf145317 220 Gene3D G3DSA:3.90.70.10 52 220 1.3E-10 T 29-03-2018 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Pfam PF01756 Acyl-CoA oxidase 500 630 5.6E-21 T 29-03-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Gene3D G3DSA:1.10.540.10 9 132 3.2E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Gene3D G3DSA:1.20.140.10 249 455 1.2E-43 T 29-03-2018 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 247 8.2E-18 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Gene3D G3DSA:2.40.110.10 133 248 1.5E-24 T 29-03-2018 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 PIRSF PIRSF000168 1 639 9.1E-182 T 29-03-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Gene3D G3DSA:1.20.140.10 499 628 2.3E-35 T 29-03-2018 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 SUPERFAMILY SSF47203 495 631 3.03E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 SUPERFAMILY SSF47203 277 461 6.6E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 441 3.6E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16470 ac63e0fe90df30060d4a693723b30d2e 646 SUPERFAMILY SSF56645 19 260 6.68E-49 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 Gene3D G3DSA:3.10.290.10 2 70 1.2E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 SMART SM00363 15 72 0.0027 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 305 2.3E-88 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 Pfam PF00849 RNA pseudouridylate synthase 89 243 1.6E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 SUPERFAMILY SSF55120 74 305 5.28E-68 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS10960 e3c15d3ab73793d82ceb33aa4cb72ea3 308 Gene3D G3DSA:3.30.2350.10 80 308 4.4E-62 T 29-03-2018 MSG_RS08840 9cd7c317b5376615bd38b618aff0513b 175 SUPERFAMILY SSF55729 11 133 3.31E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS08840 9cd7c317b5376615bd38b618aff0513b 175 Pfam PF00583 Acetyltransferase (GNAT) family 48 128 1.4E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS08840 9cd7c317b5376615bd38b618aff0513b 175 Gene3D G3DSA:3.40.630.30 1 149 1.1E-18 T 29-03-2018 MSG_RS03410 79ffa1c4aed266245241d8e5db59d72e 139 Pfam PF10783 Protein of unknown function (DUF2599) 36 133 3.3E-39 T 29-03-2018 IPR019719 Protein of unknown function DUF2599 MSG_RS21525 34c4871389d7c679f73e56a8ec625601 301 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 169 284 3.4E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21525 34c4871389d7c679f73e56a8ec625601 301 Gene3D G3DSA:1.20.140.10 160 287 1.3E-26 T 29-03-2018 MSG_RS21525 34c4871389d7c679f73e56a8ec625601 301 SUPERFAMILY SSF56645 1 148 1.6E-5 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS21525 34c4871389d7c679f73e56a8ec625601 301 Gene3D G3DSA:1.10.540.10 1 103 4.6E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21525 34c4871389d7c679f73e56a8ec625601 301 SUPERFAMILY SSF47203 165 285 1.3E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 29 447 4.0E-185 T 29-03-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 Pfam PF00425 chorismate binding enzyme 185 437 2.4E-65 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 PRINTS PR00095 Anthranilate synthase component I signature 394 408 1.1E-5 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 PRINTS PR00095 Anthranilate synthase component I signature 285 298 1.1E-5 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 PRINTS PR00095 Anthranilate synthase component I signature 379 393 1.1E-5 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 Gene3D G3DSA:3.60.120.10 3 448 3.1E-86 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS16830 fb939c6839143bd9319c860ab965811b 449 SUPERFAMILY SSF56322 26 445 2.22E-94 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS04355 255f7cdaa728b2bc60eba58efa49042c 243 SUPERFAMILY SSF102215 23 234 3.27E-59 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MSG_RS04355 255f7cdaa728b2bc60eba58efa49042c 243 TIGRFAM TIGR03964 mycofact_creat: mycofactocin system creatininase family protein 15 242 1.9E-110 T 29-03-2018 IPR023871 Mycofactocin system creatininase family protein MSG_RS04355 255f7cdaa728b2bc60eba58efa49042c 243 Pfam PF02633 Creatinine amidohydrolase 22 229 4.1E-58 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MSG_RS04355 255f7cdaa728b2bc60eba58efa49042c 243 Gene3D G3DSA:3.40.50.10310 9 236 1.3E-65 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MSG_RS06810 baec502bc9bde44e06f41912ff4e1302 401 Gene3D G3DSA:3.40.50.10540 1 401 8.0E-137 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS06810 baec502bc9bde44e06f41912ff4e1302 401 SUPERFAMILY SSF89796 5 400 1.57E-129 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS06810 baec502bc9bde44e06f41912ff4e1302 401 Pfam PF02515 CoA-transferase family III 7 376 3.9E-124 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS06575 0327671937e7e1c1a32d04b02c3e8f98 251 Gene3D G3DSA:3.30.750.24 3 116 5.4E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS06575 0327671937e7e1c1a32d04b02c3e8f98 251 Gene3D G3DSA:3.30.565.10 117 250 1.8E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS06575 0327671937e7e1c1a32d04b02c3e8f98 251 SUPERFAMILY SSF52091 8 117 8.04E-11 T 29-03-2018 IPR002645 STAS domain MSG_RS06575 0327671937e7e1c1a32d04b02c3e8f98 251 Pfam PF01740 STAS domain 9 106 3.3E-5 T 29-03-2018 IPR002645 STAS domain MSG_RS10860 0bba9f115e39451befd32e32be599194 246 Pfam PF01061 ABC-2 type transporter 4 210 4.9E-14 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS10860 0bba9f115e39451befd32e32be599194 246 PIRSF PIRSF006648 1 246 7.3E-67 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 331 1.0E-124 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 SUPERFAMILY SSF51735 118 292 1.85E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 SMART SM00829 13 329 1.2E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 SUPERFAMILY SSF50129 4 146 1.07E-36 T 29-03-2018 IPR011032 GroES-like MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 Pfam PF00107 Zinc-binding dehydrogenase 163 273 7.1E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 Gene3D G3DSA:3.40.50.720 140 329 3.9E-17 T 29-03-2018 MSG_RS06830 dc18876b08a381acc89fee7856015c68 335 Gene3D G3DSA:3.90.180.10 1 139 3.0E-25 T 29-03-2018 MSG_RS00250 b06cae8899a2fbfc6358d21b48c6de85 428 Pfam PF07690 Major Facilitator Superfamily 47 371 2.0E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS00250 b06cae8899a2fbfc6358d21b48c6de85 428 SUPERFAMILY SSF103473 24 418 1.44E-20 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS00250 b06cae8899a2fbfc6358d21b48c6de85 428 Gene3D G3DSA:1.20.1250.20 231 426 2.7E-8 T 29-03-2018 MSG_RS00250 b06cae8899a2fbfc6358d21b48c6de85 428 Gene3D G3DSA:1.20.1250.20 3 217 8.6E-12 T 29-03-2018 MSG_RS17665 531e4ab55fb427d962f7333bcaed5f92 148 Pfam PF01575 MaoC like domain 24 110 4.0E-9 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS17665 531e4ab55fb427d962f7333bcaed5f92 148 SUPERFAMILY SSF54637 6 147 1.09E-23 T 29-03-2018 IPR029069 HotDog domain MSG_RS17665 531e4ab55fb427d962f7333bcaed5f92 148 Gene3D G3DSA:3.10.129.10 1 148 8.0E-25 T 29-03-2018 MSG_RS12135 76b53a7454ebde17ffe63d7794d33a2f 147 Pfam PF13577 SnoaL-like domain 5 131 2.7E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS12135 76b53a7454ebde17ffe63d7794d33a2f 147 Gene3D G3DSA:3.10.450.50 2 147 8.9E-25 T 29-03-2018 MSG_RS12135 76b53a7454ebde17ffe63d7794d33a2f 147 SUPERFAMILY SSF54427 6 141 2.3E-25 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS10555 8dc84685365c498883a16d48069231bb 310 SUPERFAMILY SSF52540 4 224 4.71E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10555 8dc84685365c498883a16d48069231bb 310 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10555 8dc84685365c498883a16d48069231bb 310 Gene3D G3DSA:3.40.50.300 5 241 2.8E-57 T 29-03-2018 MSG_RS10555 8dc84685365c498883a16d48069231bb 310 SMART SM00382 33 211 5.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10555 8dc84685365c498883a16d48069231bb 310 Pfam PF00005 ABC transporter 25 163 1.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SUPERFAMILY SSF52540 460 672 5.34E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 Pfam PF01580 FtsK/SpoIIIE family 462 672 2.5E-22 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 Pfam PF01580 FtsK/SpoIIIE family 820 1093 2.2E-77 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SMART SM00382 1167 1351 0.81 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SMART SM00382 491 669 0.25 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SMART SM00382 865 1065 6.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SUPERFAMILY SSF52540 806 1058 1.88E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 Gene3D G3DSA:3.40.50.300 398 680 9.8E-19 T 29-03-2018 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 Gene3D G3DSA:3.40.50.300 1099 1345 7.5E-6 T 29-03-2018 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 Gene3D G3DSA:3.40.50.300 843 1062 1.1E-11 T 29-03-2018 MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 SUPERFAMILY SSF52540 1149 1316 2.67E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 791 1381 2.4E-165 T 29-03-2018 IPR023837 EccCb-like, Actinobacteria MSG_RS12635 347cb627bd6b6b65bda3aeeea8e72017 1388 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 25 716 1.5E-213 T 29-03-2018 IPR023836 EccCa-like, Actinobacteria MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 Pfam PF01575 MaoC like domain 161 266 9.0E-31 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 Gene3D G3DSA:3.10.129.10 11 157 1.4E-36 T 29-03-2018 MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 Gene3D G3DSA:3.10.129.10 158 286 1.9E-28 T 29-03-2018 MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 SUPERFAMILY SSF54637 160 271 5.04E-30 T 29-03-2018 IPR029069 HotDog domain MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 SUPERFAMILY SSF54637 8 155 4.82E-36 T 29-03-2018 IPR029069 HotDog domain MSG_RS05210 f758a5a16ffdfd0fc235aa11894a0c8d 291 Pfam PF13452 N-terminal half of MaoC dehydratase 7 127 1.1E-7 T 29-03-2018 MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 SUPERFAMILY SSF51735 8 274 6.25E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 Gene3D G3DSA:3.40.50.720 4 274 8.8E-70 T 29-03-2018 MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 8 273 9.0E-110 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 271 4.9E-50 T 29-03-2018 MSG_RS04310 50297a0172dfd32674d250a11e970c55 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS11710 8ab51267c83b43bc98c93d3732fa4b9c 393 SUPERFAMILY SSF63999 178 301 3.01E-11 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MSG_RS11710 8ab51267c83b43bc98c93d3732fa4b9c 393 Pfam PF12555 Thiamine pyrophosphokinase C terminal 334 384 6.1E-16 T 29-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal MSG_RS00670 b99a9b41246ed941df151bf186899cce 361 SUPERFAMILY SSF51679 33 358 2.21E-90 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00670 b99a9b41246ed941df151bf186899cce 361 Pfam PF00296 Luciferase-like monooxygenase 4 334 5.9E-88 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00670 b99a9b41246ed941df151bf186899cce 361 Gene3D G3DSA:3.20.20.30 1 361 1.5E-85 T 29-03-2018 MSG_RS05935 3d4731fadb7732727c5bd5f384bfd27d 461 PIRSF PIRSF006060 1 452 1.2E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS05935 3d4731fadb7732727c5bd5f384bfd27d 461 Pfam PF00324 Amino acid permease 19 445 1.9E-101 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MSG_RS05935 3d4731fadb7732727c5bd5f384bfd27d 461 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MSG_RS01830 42ebb0c0c89036a7c613592899fcaeb7 249 Pfam PF10979 Protein of unknown function (DUF2786) 5 43 4.7E-13 T 29-03-2018 IPR024498 Domain of unknown function DUF2786 MSG_RS01830 42ebb0c0c89036a7c613592899fcaeb7 249 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 1 248 2.0E-96 T 29-03-2018 MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 SMART SM00849 359 558 2.0E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 SUPERFAMILY SSF56281 317 623 2.94E-58 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 SUPERFAMILY SSF56529 69 304 5.23E-59 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 Pfam PF00753 Metallo-beta-lactamase superfamily 360 558 2.1E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 Pfam PF10370 Domain of unknown function (DUF2437) 1 66 3.7E-5 T 29-03-2018 IPR018833 Domain of unknown function DUF2437 MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 Gene3D G3DSA:3.60.15.10 330 584 5.4E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 304 6.3E-50 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS20440 bac690ccf04527a6e9499795807ca311 647 Gene3D G3DSA:3.90.850.10 29 303 2.0E-57 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS24075 653b64c916597e32ee8a14df7bc64962 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 87 156 1.0E-11 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MSG_RS24075 653b64c916597e32ee8a14df7bc64962 159 Gene3D G3DSA:3.10.50.30 75 159 4.2E-15 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MSG_RS24075 653b64c916597e32ee8a14df7bc64962 159 PIRSF PIRSF006092 1 159 8.1E-15 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MSG_RS24075 653b64c916597e32ee8a14df7bc64962 159 Gene3D G3DSA:1.10.287.180 7 74 6.6E-6 T 29-03-2018 MSG_RS24075 653b64c916597e32ee8a14df7bc64962 159 SUPERFAMILY SSF54534 86 156 4.19E-10 T 29-03-2018 MSG_RS20465 aa0f74fb99726c8b0aa83d7c22e78fbe 315 Gene3D G3DSA:3.40.1190.20 3 304 2.5E-45 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS20465 aa0f74fb99726c8b0aa83d7c22e78fbe 315 SUPERFAMILY SSF53613 5 293 9.82E-51 T 29-03-2018 IPR029056 Ribokinase-like MSG_RS20465 aa0f74fb99726c8b0aa83d7c22e78fbe 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 230 243 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MSG_RS20465 aa0f74fb99726c8b0aa83d7c22e78fbe 315 Pfam PF00294 pfkB family carbohydrate kinase 13 290 7.1E-36 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MSG_RS03730 5025597b2e4b4ea5b76a539cf0440c87 292 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 286 20.566 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MSG_RS03730 5025597b2e4b4ea5b76a539cf0440c87 292 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 283 4.3E-114 T 29-03-2018 MSG_RS03730 5025597b2e4b4ea5b76a539cf0440c87 292 PIRSF PIRSF005355 1 291 8.5E-83 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 MSG_RS03730 5025597b2e4b4ea5b76a539cf0440c87 292 Pfam PF01040 UbiA prenyltransferase family 20 250 1.7E-30 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MSG_RS01965 3b4b41a9ab9db0dba9702a9a0077ca37 325 SUPERFAMILY SSF52096 135 323 1.04E-48 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS01965 3b4b41a9ab9db0dba9702a9a0077ca37 325 Gene3D G3DSA:3.90.226.10 127 325 3.2E-50 T 29-03-2018 MSG_RS01965 3b4b41a9ab9db0dba9702a9a0077ca37 325 Pfam PF00378 Enoyl-CoA hydratase/isomerase 143 322 2.6E-34 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 1.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 69 84 1.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 237 251 1.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 1.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 SUPERFAMILY SSF53474 21 292 3.75E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22635 4591b355a995277baa6a39aad2408954 295 Pfam PF00561 alpha/beta hydrolase fold 43 279 8.0E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00412 Epoxide hydrolase signature 128 141 1.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00412 Epoxide hydrolase signature 69 84 1.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 PRINTS PR00412 Epoxide hydrolase signature 268 290 1.2E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22635 4591b355a995277baa6a39aad2408954 295 Gene3D G3DSA:3.40.50.1820 10 293 1.4E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 Pfam PF00672 HAMP domain 203 259 6.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 SUPERFAMILY SSF47384 262 339 6.08E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 495 1.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 Gene3D G3DSA:1.10.287.130 252 335 2.1E-15 T 29-03-2018 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 Gene3D G3DSA:3.30.565.10 340 497 3.7E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 SUPERFAMILY SSF55874 329 495 9.95E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 SMART SM00304 202 264 7.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 SMART SM00388 272 339 1.1E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 SMART SM00387 382 497 6.9E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 339 2.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 4.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 438 4.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 476 4.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS19795 2064bce5058e5743fecebae8c1420235 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 452 4.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MSG_RS03160 865d4bf468e81079e46e76b1af989424 272 Gene3D G3DSA:1.10.12.10 213 262 6.4E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS03160 865d4bf468e81079e46e76b1af989424 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 259 4.3E-47 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS03160 865d4bf468e81079e46e76b1af989424 272 Gene3D G3DSA:3.90.226.10 1 212 8.0E-53 T 29-03-2018 MSG_RS03160 865d4bf468e81079e46e76b1af989424 272 SUPERFAMILY SSF52096 2 259 2.49E-70 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 Gene3D G3DSA:2.40.50.100 281 360 1.5E-17 T 29-03-2018 MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 SUPERFAMILY SSF52540 12 240 5.21E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 Pfam PF00005 ABC transporter 16 166 6.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 Pfam PF03459 TOBE domain 299 362 2.8E-11 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 Gene3D G3DSA:3.40.50.300 15 243 1.4E-57 T 29-03-2018 MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 SUPERFAMILY SSF50331 241 364 6.81E-16 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS13005 3de77f879cee77e29f94d6620bda374c 373 SMART SM00382 23 216 6.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS20280 bcd1ea33f15ed93a40ecef3d27690756 200 Pfam PF08044 Domain of unknown function (DUF1707) 18 69 4.9E-15 T 29-03-2018 IPR012551 Protein of unknown function DUF1707 MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Gene3D G3DSA:3.30.70.120 1 114 1.1E-20 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Gene3D G3DSA:3.30.70.120 240 351 2.7E-24 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Gene3D G3DSA:3.30.70.120 118 226 4.9E-18 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 SUPERFAMILY SSF54913 4 105 2.45E-15 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Pfam PF02641 Uncharacterized ACR, COG1993 245 340 5.5E-21 T 29-03-2018 IPR003793 Domain of unknown function DUF190 MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Pfam PF02641 Uncharacterized ACR, COG1993 7 103 2.6E-16 T 29-03-2018 IPR003793 Domain of unknown function DUF190 MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 Pfam PF02641 Uncharacterized ACR, COG1993 124 218 8.4E-17 T 29-03-2018 IPR003793 Domain of unknown function DUF190 MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 SUPERFAMILY SSF54913 121 219 4.67E-20 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MSG_RS07065 ea6b48ec21eecf454115d517d127fac4 362 SUPERFAMILY SSF54913 244 340 1.25E-21 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 9.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 SUPERFAMILY SSF46785 6 78 9.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 SMART SM00895 84 206 4.7E-16 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 Gene3D G3DSA:1.20.120.530 70 219 6.5E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 SMART SM00345 16 74 1.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 Gene3D G3DSA:1.10.10.10 2 69 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 SUPERFAMILY SSF48008 81 206 2.62E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS17985 fc37f2eacf7fd2240fd9ad4978c3c0ee 225 Pfam PF07729 FCD domain 86 205 3.9E-23 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 83 6.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 Pfam PF07729 FCD domain 93 219 5.5E-15 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 SUPERFAMILY SSF46785 16 87 7.43E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 Gene3D G3DSA:1.10.10.10 5 79 3.5E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 SMART SM00895 93 220 3.9E-7 T 29-03-2018 IPR011711 GntR, C-terminal MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 SUPERFAMILY SSF48008 90 227 4.71E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 SMART SM00345 25 83 1.9E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS01370 afe077ef3e7c4dc1ac3285437c3beaf0 234 Gene3D G3DSA:1.20.120.530 80 233 3.7E-21 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MSG_RS12950 ecb852a15ab34a3d7a37a0f7b6157435 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 94 3.0E-35 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12950 ecb852a15ab34a3d7a37a0f7b6157435 103 SUPERFAMILY SSF51278 1 102 1.57E-40 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12950 ecb852a15ab34a3d7a37a0f7b6157435 103 Gene3D G3DSA:2.10.150.10 1 101 2.3E-40 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12950 ecb852a15ab34a3d7a37a0f7b6157435 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 28.653 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS12950 ecb852a15ab34a3d7a37a0f7b6157435 103 Pfam PF00699 Urease beta subunit 3 96 1.2E-39 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MSG_RS07950 67d72ab4b5dfe8289a4dbfb7f0fc296a 373 Gene3D G3DSA:3.40.50.1820 56 373 1.7E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS07950 67d72ab4b5dfe8289a4dbfb7f0fc296a 373 SUPERFAMILY SSF53474 104 370 1.54E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS07950 67d72ab4b5dfe8289a4dbfb7f0fc296a 373 Pfam PF07859 alpha/beta hydrolase fold 139 346 1.3E-71 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 Gene3D G3DSA:3.40.47.10 256 379 3.4E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 PIRSF PIRSF000429 1 382 3.2E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 9.8E-135 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 SUPERFAMILY SSF53901 3 259 9.77E-73 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 Gene3D G3DSA:3.40.47.10 1 255 8.2E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 Pfam PF02803 Thiolase, C-terminal domain 259 380 6.8E-43 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 SUPERFAMILY SSF53901 260 381 1.29E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS19265 2ee8743338ab183e18ca16813b338379 382 Pfam PF00108 Thiolase, N-terminal domain 5 251 6.3E-72 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS15255 512dfdf27cbc8c2111c21f42dbc4074e 129 Gene3D G3DSA:3.30.530.20 50 123 0.0084 T 29-03-2018 IPR023393 START-like domain MSG_RS15255 512dfdf27cbc8c2111c21f42dbc4074e 129 SUPERFAMILY SSF55961 5 92 3.88E-9 T 29-03-2018 MSG_RS15255 512dfdf27cbc8c2111c21f42dbc4074e 129 Gene3D G3DSA:3.30.530.20 4 49 7.8E-5 T 29-03-2018 IPR023393 START-like domain MSG_RS03925 9c273d49670470a7f4c3b4447528d89d 382 Pfam PF08808 RES domain 199 349 1.7E-16 T 29-03-2018 IPR014914 RES domain MSG_RS03925 9c273d49670470a7f4c3b4447528d89d 382 SMART SM00953 212 350 5.2E-5 T 29-03-2018 IPR014914 RES domain MSG_RS10650 59f7599938f2ee690916f086f53a996d 245 SUPERFAMILY SSF54001 112 231 1.86E-31 T 29-03-2018 MSG_RS10650 59f7599938f2ee690916f086f53a996d 245 Pfam PF00877 NlpC/P60 family 128 242 3.6E-31 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MSG_RS10650 59f7599938f2ee690916f086f53a996d 245 Gene3D G3DSA:3.90.1720.10 109 245 1.2E-34 T 29-03-2018 MSG_RS06585 fec5b9bcd45eddc787958aea7306873c 298 Pfam PF01339 CheB methylesterase 13 184 5.7E-45 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MSG_RS06585 fec5b9bcd45eddc787958aea7306873c 298 SUPERFAMILY SSF52738 8 189 1.29E-43 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MSG_RS06585 fec5b9bcd45eddc787958aea7306873c 298 Gene3D G3DSA:3.40.50.180 6 195 6.6E-49 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MSG_RS06775 edd088c02795606001460d9417e5a0f9 137 Gene3D G3DSA:3.40.50.2300 2 135 5.9E-11 T 29-03-2018 MSG_RS06775 edd088c02795606001460d9417e5a0f9 137 SUPERFAMILY SSF52172 13 133 3.22E-7 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS10765 e68568bba1d73be2b88942f47cb4f083 418 Gene3D G3DSA:3.40.50.2000 1 253 3.3E-35 T 29-03-2018 MSG_RS10765 e68568bba1d73be2b88942f47cb4f083 418 SUPERFAMILY SSF53756 1 413 4.32E-90 T 29-03-2018 MSG_RS10765 e68568bba1d73be2b88942f47cb4f083 418 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 73 1.3E-7 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS10765 e68568bba1d73be2b88942f47cb4f083 418 Gene3D G3DSA:3.40.50.2000 254 396 1.5E-26 T 29-03-2018 MSG_RS02410 621162ffe3ecd3d8b06ef548beda9378 334 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 13 298 5.7E-65 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS02410 621162ffe3ecd3d8b06ef548beda9378 334 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 132 216 2.1E-11 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS03640 9f505f863bed80b7044a05686116b37e 717 Pfam PF01757 Acyltransferase family 19 352 8.8E-22 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS03640 9f505f863bed80b7044a05686116b37e 717 SUPERFAMILY SSF52266 497 706 3.97E-5 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS03640 9f505f863bed80b7044a05686116b37e 717 Gene3D G3DSA:3.40.50.1110 488 708 1.2E-13 T 29-03-2018 MSG_RS10825 4b721f05c7e4abf704343296a0fd9933 351 SUPERFAMILY SSF53335 167 296 3.79E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10825 4b721f05c7e4abf704343296a0fd9933 351 Gene3D G3DSA:3.40.50.150 73 307 4.7E-7 T 29-03-2018 MSG_RS10825 4b721f05c7e4abf704343296a0fd9933 351 TIGRFAM TIGR04371 methyltran_NanM: putative sugar O-methyltransferase 23 303 9.4E-35 T 29-03-2018 IPR030807 Putative sugar O-methyltransferase MSG_RS14405 d2f9bf855cf68cefd5620ed75368303b 353 SUPERFAMILY SSF140459 4 172 3.14E-52 T 29-03-2018 MSG_RS14405 d2f9bf855cf68cefd5620ed75368303b 353 Gene3D G3DSA:1.10.287.1060 22 106 3.4E-5 T 29-03-2018 MSG_RS14405 d2f9bf855cf68cefd5620ed75368303b 353 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 267 349 1.3E-13 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS14405 d2f9bf855cf68cefd5620ed75368303b 353 Pfam PF00823 PPE family 7 159 9.1E-52 T 29-03-2018 IPR000030 PPE family MSG_RS14445 68fa9e77e07420dc2ac099bcc2988d32 317 SUPERFAMILY SSF161098 70 299 3.79E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS14445 68fa9e77e07420dc2ac099bcc2988d32 317 Gene3D G3DSA:1.10.3720.10 30 314 2.7E-53 T 29-03-2018 MSG_RS14445 68fa9e77e07420dc2ac099bcc2988d32 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 307 2.4E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS01935 e404d30c5114c58fb4baf2296c4670fb 269 Pfam PF02390 Putative methyltransferase 95 262 4.2E-52 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MSG_RS01935 e404d30c5114c58fb4baf2296c4670fb 269 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 89 267 2.7E-37 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MSG_RS01935 e404d30c5114c58fb4baf2296c4670fb 269 SUPERFAMILY SSF53335 85 266 7.17E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01935 e404d30c5114c58fb4baf2296c4670fb 269 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 51 268 26.771 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MSG_RS01935 e404d30c5114c58fb4baf2296c4670fb 269 Gene3D G3DSA:3.40.50.150 58 269 8.1E-26 T 29-03-2018 MSG_RS08375 aaab161d7d1f50371bc0e6b602562f81 168 SUPERFAMILY SSF52833 2 147 9.42E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS08375 aaab161d7d1f50371bc0e6b602562f81 168 Pfam PF00578 AhpC/TSA family 38 139 8.6E-14 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS08375 aaab161d7d1f50371bc0e6b602562f81 168 Gene3D G3DSA:3.40.30.10 24 166 4.2E-24 T 29-03-2018 MSG_RS04010 b0c77445606cfab296b9a9fdea6dc34b 795 Gene3D G3DSA:1.10.510.10 332 522 2.2E-4 T 29-03-2018 MSG_RS04010 b0c77445606cfab296b9a9fdea6dc34b 795 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 492 782 2.8E-32 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MSG_RS04010 b0c77445606cfab296b9a9fdea6dc34b 795 SUPERFAMILY SSF56112 292 397 5.5E-5 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 Pfam PF01455 HupF/HypC family 1 69 2.6E-23 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 75 4.2E-17 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.2E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 2.2E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 44 60 2.2E-13 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MSG_RS14045 d9a9e7731793aca5791450743578c8f6 88 SUPERFAMILY SSF159127 1 78 1.01E-19 T 29-03-2018 MSG_RS07680 e5c94bce2851a94ddcb70c7f86ad833e 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 33 366 1.4E-78 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS07680 e5c94bce2851a94ddcb70c7f86ad833e 370 Gene3D G3DSA:3.40.640.10 8 245 4.3E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS07680 e5c94bce2851a94ddcb70c7f86ad833e 370 Gene3D G3DSA:3.90.1150.10 247 367 1.0E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS07680 e5c94bce2851a94ddcb70c7f86ad833e 370 SUPERFAMILY SSF53383 24 366 7.13E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS07680 e5c94bce2851a94ddcb70c7f86ad833e 370 PIRSF PIRSF001434 3 369 6.8E-98 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 SUPERFAMILY SSF52540 146 345 1.65E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 SUPERFAMILY SSF52540 393 510 5.17E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 SUPERFAMILY SSF52540 290 360 5.17E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 Gene3D G3DSA:3.40.50.300 380 515 1.0E-16 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 538 4.6E-42 T 29-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 1.3E-34 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 1.3E-34 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 1.3E-34 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 1.3E-34 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 1.3E-34 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 Gene3D G3DSA:3.40.50.300 175 355 7.1E-26 T 29-03-2018 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 Pfam PF04851 Type III restriction enzyme, res subunit 181 327 2.2E-14 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 SMART SM00490 423 500 7.9E-11 T 29-03-2018 IPR001650 Helicase, C-terminal MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 Pfam PF13625 Helicase conserved C-terminal domain 6 134 8.9E-46 T 29-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MSG_RS20830 bf82153dd5c53cc4cbc28e1376e14db8 549 SMART SM00487 178 353 4.0E-23 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MSG_RS03570 e6c678aebdf4e5d46fc75b9c77a4ddf5 435 Gene3D G3DSA:1.10.287.1060 145 222 0.0067 T 29-03-2018 MSG_RS03570 e6c678aebdf4e5d46fc75b9c77a4ddf5 435 Gene3D G3DSA:1.10.287.1060 223 304 0.012 T 29-03-2018 MSG_RS03570 e6c678aebdf4e5d46fc75b9c77a4ddf5 435 Gene3D G3DSA:1.10.287.1060 1 98 2.5E-7 T 29-03-2018 MSG_RS00370 62a3fc17fe259f82e0686981c8de0ef6 196 Pfam PF01965 DJ-1/PfpI family 4 173 2.4E-24 T 29-03-2018 IPR002818 DJ-1/PfpI MSG_RS00370 62a3fc17fe259f82e0686981c8de0ef6 196 SUPERFAMILY SSF52317 3 193 5.19E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS00370 62a3fc17fe259f82e0686981c8de0ef6 196 Gene3D G3DSA:3.40.50.880 1 196 2.0E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS02190 70e86a35ab752cb810659e89bbdbb745 163 SUPERFAMILY SSF50475 12 161 1.42E-36 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS02190 70e86a35ab752cb810659e89bbdbb745 163 Gene3D G3DSA:2.30.110.10 4 163 1.3E-33 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS02190 70e86a35ab752cb810659e89bbdbb745 163 SMART SM00903 16 159 1.6E-38 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS02190 70e86a35ab752cb810659e89bbdbb745 163 Pfam PF01613 Flavin reductase like domain 17 160 4.5E-25 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MSG_RS24605 f86e4feae27aeea115e343bb7c39ac7c 306 SUPERFAMILY SSF52540 56 269 2.77E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24605 f86e4feae27aeea115e343bb7c39ac7c 306 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 59 265 1.8E-7 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS24605 f86e4feae27aeea115e343bb7c39ac7c 306 Gene3D G3DSA:3.40.50.300 35 299 9.1E-26 T 29-03-2018 MSG_RS00520 120b3687d13b91838b6a3ad1c11d8221 277 Gene3D G3DSA:3.20.20.30 11 223 2.1E-61 T 29-03-2018 MSG_RS00520 120b3687d13b91838b6a3ad1c11d8221 277 Gene3D G3DSA:3.20.20.30 224 273 0.068 T 29-03-2018 MSG_RS00520 120b3687d13b91838b6a3ad1c11d8221 277 Pfam PF00296 Luciferase-like monooxygenase 15 221 1.3E-51 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00520 120b3687d13b91838b6a3ad1c11d8221 277 SUPERFAMILY SSF51679 1 272 6.8E-63 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00520 120b3687d13b91838b6a3ad1c11d8221 277 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 220 1.5E-81 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS19855 94737189bdec4fbdb00fd5d983bfaa04 369 SUPERFAMILY SSF101386 94 186 3.36E-17 T 29-03-2018 MSG_RS19855 94737189bdec4fbdb00fd5d983bfaa04 369 Gene3D G3DSA:1.10.287.1080 90 207 1.8E-31 T 29-03-2018 MSG_RS19855 94737189bdec4fbdb00fd5d983bfaa04 369 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 111 185 3.8E-22 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 Gene3D G3DSA:2.40.50.140 2 83 7.4E-21 T 29-03-2018 MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 333 409 8.3E-9 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 SUPERFAMILY SSF53335 73 409 3.99E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 Gene3D G3DSA:3.40.50.150 204 410 6.2E-30 T 29-03-2018 MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 SUPERFAMILY SSF50249 20 71 5.71E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS09105 6921e8660a59b932f9cee41ddab3e20b 414 Pfam PF01938 TRAM domain 22 62 1.0E-6 T 29-03-2018 IPR002792 TRAM domain MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 SUPERFAMILY SSF48264 11 392 1.7E-77 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 Gene3D G3DSA:1.10.630.10 26 390 2.2E-57 T 29-03-2018 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 284 311 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 342 353 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 189 211 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 333 342 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 88 99 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 134 150 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 151 166 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00359 B-class P450 signature 267 278 4.5E-31 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 Pfam PF00067 Cytochrome P450 199 313 1.1E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 Pfam PF00067 Cytochrome P450 328 391 4.5E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00385 P450 superfamily signature 333 342 1.4E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00385 P450 superfamily signature 342 353 1.4E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00385 P450 superfamily signature 267 278 1.4E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS12640 7184c9527d3f57f4e7d3da052e3adeb1 393 PRINTS PR00385 P450 superfamily signature 232 249 1.4E-8 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS20245 2501f37cf2b8aa47fa4a390f697415da 57 Pfam PF01783 Ribosomal L32p protein family 2 46 2.2E-11 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS20245 2501f37cf2b8aa47fa4a390f697415da 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.027 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS20245 2501f37cf2b8aa47fa4a390f697415da 57 SUPERFAMILY SSF57829 1 38 1.89E-7 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MSG_RS20245 2501f37cf2b8aa47fa4a390f697415da 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 48 7.5E-12 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 ProSitePatterns PS01218 TatC family signature. 194 213 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 28 281 17.784 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 126 144 1.2E-40 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 33 60 1.2E-40 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 194 222 1.2E-40 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 144 170 1.2E-40 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 34 266 9.4E-76 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS14720 215510ba847ada5c20e44a8b887d4875 322 Pfam PF00902 Sec-independent protein translocase protein (TatC) 36 260 1.8E-60 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MSG_RS19560 5a0b0991a7f8c4b63a7384350427cbfc 291 Pfam PF01522 Polysaccharide deacetylase 47 162 3.8E-32 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS19560 5a0b0991a7f8c4b63a7384350427cbfc 291 Gene3D G3DSA:3.20.20.370 35 236 2.8E-49 T 29-03-2018 MSG_RS19560 5a0b0991a7f8c4b63a7384350427cbfc 291 SUPERFAMILY SSF88713 47 231 5.34E-57 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 Gene3D G3DSA:3.30.9.10 153 323 2.3E-45 T 29-03-2018 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 1 308 1.1E-68 T 29-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 SUPERFAMILY SSF51905 261 347 1.75E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 SUPERFAMILY SSF51905 1 163 1.75E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 2.6E-6 T 29-03-2018 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 20 2.6E-6 T 29-03-2018 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 Pfam PF01494 FAD binding domain 1 197 5.0E-13 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS03880 c0557bcd9d0469e98954efd9b01086dc 404 Gene3D G3DSA:3.50.50.60 1 152 5.8E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18480 c2b3cdaf16a1beae5e54c81aa86fa3b1 159 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 155 3.9E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18480 c2b3cdaf16a1beae5e54c81aa86fa3b1 159 SUPERFAMILY SSF56770 33 157 7.2E-47 T 29-03-2018 MSG_RS18480 c2b3cdaf16a1beae5e54c81aa86fa3b1 159 Gene3D G3DSA:3.40.50.700 31 159 2.1E-25 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS00115 2299707eff4fcbb3a992e6ec7ba6bb48 469 Pfam PF01098 Cell cycle protein 81 445 3.6E-106 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MSG_RS14725 597c42fe2667970f3a9e44b4d11b37ea 88 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 9.3E-22 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MSG_RS14725 597c42fe2667970f3a9e44b4d11b37ea 88 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 22.061 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MSG_RS14725 597c42fe2667970f3a9e44b4d11b37ea 88 Pfam PF02416 mttA/Hcf106 family 4 53 7.8E-23 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MSG_RS06230 d1e05fa4d7005d893d13d34bb4a8e0f3 231 Gene3D G3DSA:1.20.1260.10 22 231 3.6E-36 T 29-03-2018 IPR012347 Ferritin-related MSG_RS06230 d1e05fa4d7005d893d13d34bb4a8e0f3 231 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 27 202 4.0E-60 T 29-03-2018 MSG_RS06230 d1e05fa4d7005d893d13d34bb4a8e0f3 231 SUPERFAMILY SSF47240 21 136 3.65E-8 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 535 1.6E-211 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 Gene3D G3DSA:1.20.210.10 26 539 3.9E-197 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 1.7E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 SUPERFAMILY SSF81442 28 538 2.35E-176 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 4.2E-148 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS19590 9d36c1a1d8320d511ec300d9894868ce 577 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS23405 c847c55edb68c079152a4b62b1b3aa53 493 Gene3D G3DSA:3.40.1800.10 327 391 6.3E-6 T 29-03-2018 MSG_RS23405 c847c55edb68c079152a4b62b1b3aa53 493 Pfam PF02720 Domain of unknown function (DUF222) 34 339 2.1E-83 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS23405 c847c55edb68c079152a4b62b1b3aa53 493 SMART SM00507 330 382 7.3E-4 T 29-03-2018 IPR003615 HNH nuclease MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 Gene3D G3DSA:3.40.50.300 55 265 9.7E-39 T 29-03-2018 MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 Gene3D G3DSA:1.20.5.170 12 53 7.2E-19 T 29-03-2018 MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 Pfam PF03308 ArgK protein 25 297 2.4E-119 T 29-03-2018 MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 Gene3D G3DSA:1.10.287.130 267 327 8.5E-25 T 29-03-2018 MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 20 325 1.1E-129 T 29-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 SUPERFAMILY SSF52540 10 326 1.52E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10735 69cd56141a578f084e3290b3544a346f 330 SMART SM00382 56 230 0.0031 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11430 fb17153f466b3af13315c58fb309e6c1 267 SUPERFAMILY SSF54001 86 237 1.68E-28 T 29-03-2018 MSG_RS11430 fb17153f466b3af13315c58fb309e6c1 267 SMART SM00460 151 211 9.4E-16 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS11430 fb17153f466b3af13315c58fb309e6c1 267 Pfam PF01841 Transglutaminase-like superfamily 115 209 4.8E-19 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS11430 fb17153f466b3af13315c58fb309e6c1 267 Gene3D G3DSA:3.90.260.10 116 255 1.6E-5 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS10095 040ed8bff330f62329404c0608d7cce7 297 Gene3D G3DSA:1.10.3720.10 21 296 2.2E-31 T 29-03-2018 MSG_RS10095 040ed8bff330f62329404c0608d7cce7 297 SUPERFAMILY SSF161098 18 291 2.35E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS03585 7c1e5a2c984d9dd70b1e343fab361a01 85 SUPERFAMILY SSF52833 3 84 5.01E-11 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS03585 7c1e5a2c984d9dd70b1e343fab361a01 85 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 83 3.4E-16 T 29-03-2018 IPR008554 Glutaredoxin-like MSG_RS03585 7c1e5a2c984d9dd70b1e343fab361a01 85 Gene3D G3DSA:3.40.30.10 3 85 1.1E-10 T 29-03-2018 MSG_RS15230 d31464df61e0fe4da524a8f9bfedf1c0 434 Pfam PF09594 Glycosyltransferase family 87 79 323 5.4E-59 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MSG_RS15870 ebc7c1b32fb2d0f04323950d7adcea9b 115 Gene3D G3DSA:3.40.1130.10 1 109 3.4E-12 T 29-03-2018 MSG_RS15870 ebc7c1b32fb2d0f04323950d7adcea9b 115 Pfam PF01553 Acyltransferase 1 36 5.9E-7 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS15870 ebc7c1b32fb2d0f04323950d7adcea9b 115 SUPERFAMILY SSF69593 1 82 1.03E-12 T 29-03-2018 MSG_RS24370 df1d6875f71fcdd2137a701bfe4d7c4a 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 8 156 7.5E-64 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MSG_RS24370 df1d6875f71fcdd2137a701bfe4d7c4a 161 SUPERFAMILY SSF89562 7 158 3.53E-46 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS24370 df1d6875f71fcdd2137a701bfe4d7c4a 161 Pfam PF03737 Aldolase/RraA 8 156 2.2E-43 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS24370 df1d6875f71fcdd2137a701bfe4d7c4a 161 Gene3D G3DSA:3.50.30.40 2 161 4.2E-43 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MSG_RS18965 853604f1a3c2d0aa5be6c2a325c93336 154 Gene3D G3DSA:3.10.129.10 3 152 1.3E-27 T 29-03-2018 MSG_RS18965 853604f1a3c2d0aa5be6c2a325c93336 154 SUPERFAMILY SSF54637 14 141 2.69E-21 T 29-03-2018 IPR029069 HotDog domain MSG_RS18965 853604f1a3c2d0aa5be6c2a325c93336 154 Pfam PF01575 MaoC like domain 27 128 5.4E-8 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS00260 fe8b89f364dec720730d643ce462b77a 329 PIRSF PIRSF026166 1 329 3.2E-114 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter MSG_RS00260 fe8b89f364dec720730d643ce462b77a 329 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 11 319 2.1E-87 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter MSG_RS14600 7a9bfbac89fb28f2412df0a65d5d6399 221 SUPERFAMILY SSF53474 19 184 2.75E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14600 7a9bfbac89fb28f2412df0a65d5d6399 221 Pfam PF12697 Alpha/beta hydrolase family 23 172 3.0E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS14600 7a9bfbac89fb28f2412df0a65d5d6399 221 Gene3D G3DSA:3.40.50.1820 19 199 1.3E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20865 c0dc4e2fcef431cf7b591cc1295e8e70 236 PIRSF PIRSF017388 3 236 2.0E-43 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 MSG_RS20865 c0dc4e2fcef431cf7b591cc1295e8e70 236 SUPERFAMILY SSF53474 3 233 1.09E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20865 c0dc4e2fcef431cf7b591cc1295e8e70 236 Pfam PF12697 Alpha/beta hydrolase family 8 226 4.1E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS20865 c0dc4e2fcef431cf7b591cc1295e8e70 236 Gene3D G3DSA:3.40.50.1820 3 234 1.1E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10405 e7c92264cb7b0e4a25253c6803c28a27 419 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 316 394 8.0E-10 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS10405 e7c92264cb7b0e4a25253c6803c28a27 419 SUPERFAMILY SSF140459 2 173 6.54E-63 T 29-03-2018 MSG_RS10405 e7c92264cb7b0e4a25253c6803c28a27 419 Gene3D G3DSA:1.10.287.1060 20 104 1.2E-7 T 29-03-2018 MSG_RS10405 e7c92264cb7b0e4a25253c6803c28a27 419 Pfam PF00823 PPE family 5 160 1.1E-60 T 29-03-2018 IPR000030 PPE family MSG_RS01465 1fbf48321e072551f71cfd10ca8d0b27 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 234 1.7E-25 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS01465 1fbf48321e072551f71cfd10ca8d0b27 341 Gene3D G3DSA:3.40.50.720 3 333 4.7E-49 T 29-03-2018 MSG_RS01465 1fbf48321e072551f71cfd10ca8d0b27 341 SUPERFAMILY SSF51735 298 329 2.78E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01465 1fbf48321e072551f71cfd10ca8d0b27 341 SUPERFAMILY SSF51735 7 270 2.78E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 Gene3D G3DSA:3.40.47.10 129 376 1.4E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 SUPERFAMILY SSF53901 249 370 2.04E-13 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 Gene3D G3DSA:3.40.47.10 6 108 0.052 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 SUPERFAMILY SSF53901 8 211 4.8E-19 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 PIRSF PIRSF000429 72 377 8.2E-10 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS00850 2ab8732103902b69308ab1e4814bf0b9 386 PIRSF PIRSF000429 2 61 0.2 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS20425 1254e75eec2c9794b2ec19941d0f60d2 288 Gene3D G3DSA:3.20.20.30 2 241 1.9E-55 T 29-03-2018 MSG_RS20425 1254e75eec2c9794b2ec19941d0f60d2 288 Pfam PF00296 Luciferase-like monooxygenase 9 225 7.7E-43 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20425 1254e75eec2c9794b2ec19941d0f60d2 288 SUPERFAMILY SSF51679 6 285 4.19E-50 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS09055 df185866e2a98303fe48efb2fc7dbf9e 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 3.1E-45 T 29-03-2018 IPR025242 Protein of unknown function DUF4193 MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 Gene3D G3DSA:3.40.50.300 1 256 3.2E-55 T 29-03-2018 MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 3.9E-112 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 SUPERFAMILY SSF52540 5 244 6.41E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 Pfam PF00005 ABC transporter 22 176 2.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS21675 23dd895a72df94d4043dae479249e1e3 258 SMART SM00382 29 229 2.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10680 44b187e8e7c8da8bb1f1f2965fa6b092 269 SUPERFAMILY SSF51735 4 265 1.34E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10680 44b187e8e7c8da8bb1f1f2965fa6b092 269 Gene3D G3DSA:3.40.50.720 3 269 2.5E-38 T 29-03-2018 MSG_RS10680 44b187e8e7c8da8bb1f1f2965fa6b092 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 264 2.6E-57 T 29-03-2018 MSG_RS10680 44b187e8e7c8da8bb1f1f2965fa6b092 269 PIRSF PIRSF000094 2 269 8.4E-104 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MSG_RS23145 138da1494ef6f1e1d4b904219967adee 151 SUPERFAMILY SSF55298 2 150 8.95E-55 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS23145 138da1494ef6f1e1d4b904219967adee 151 Gene3D G3DSA:3.30.1330.40 1 150 2.6E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS23145 138da1494ef6f1e1d4b904219967adee 151 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 150 1.9E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS20710 77c5e7257f64e26b2606700778d74833 149 Gene3D G3DSA:3.10.180.10 6 144 5.2E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS20710 77c5e7257f64e26b2606700778d74833 149 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 129 8.3E-13 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS20710 77c5e7257f64e26b2606700778d74833 149 SUPERFAMILY SSF54593 8 130 1.48E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS18465 24e64795af4b88652d1608fe28fbbac1 220 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 24 195 6.0E-50 T 29-03-2018 MSG_RS05420 a56e819f71cd8842b1934b681a6b9508 145 Pfam PF05423 Mycobacterium membrane protein 8 144 1.2E-52 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Gene3D G3DSA:2.40.110.10 125 225 1.0E-15 T 29-03-2018 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 SUPERFAMILY SSF56645 25 223 5.1E-40 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 215 3.2E-9 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 378 4.1E-13 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 SUPERFAMILY SSF47203 236 380 4.19E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Gene3D G3DSA:1.10.540.10 7 124 1.4E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 PIRSF PIRSF016578 5 400 1.6E-21 T 29-03-2018 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Gene3D G3DSA:1.20.140.10 226 403 5.5E-19 T 29-03-2018 MSG_RS00660 2b10cd512acb0b85b4c6e63f879f5d00 412 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 121 4.3E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00620 21b68a3b4a036c3a5c5ac4c198f01d00 264 SMART SM00382 25 204 1.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS00620 21b68a3b4a036c3a5c5ac4c198f01d00 264 SUPERFAMILY SSF52540 2 209 2.08E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS00620 21b68a3b4a036c3a5c5ac4c198f01d00 264 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS00620 21b68a3b4a036c3a5c5ac4c198f01d00 264 Pfam PF00005 ABC transporter 16 154 6.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS00620 21b68a3b4a036c3a5c5ac4c198f01d00 264 Gene3D G3DSA:3.40.50.300 1 218 2.0E-56 T 29-03-2018 MSG_RS15575 3da58c8f69120dedb0ca30aec2b3712c 211 Gene3D G3DSA:3.40.50.1000 67 210 3.5E-29 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15575 3da58c8f69120dedb0ca30aec2b3712c 211 Gene3D G3DSA:1.10.150.240 12 66 4.2E-12 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MSG_RS15575 3da58c8f69120dedb0ca30aec2b3712c 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 177 9.0E-32 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15575 3da58c8f69120dedb0ca30aec2b3712c 211 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 171 1.3E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15575 3da58c8f69120dedb0ca30aec2b3712c 211 SUPERFAMILY SSF56784 1 193 4.47E-46 T 29-03-2018 IPR023214 HAD-like domain MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 SMART SM00833 229 317 5.2E-8 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 230 317 4.5E-13 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 Gene3D G3DSA:3.30.1220.10 214 318 3.5E-11 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 SUPERFAMILY SSF90002 231 317 6.8E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 SUPERFAMILY SSF52540 3 184 3.99E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 182 1.9E-35 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MSG_RS13790 98cb624627199ae5fab973a9c0aab9a6 340 Gene3D G3DSA:3.40.50.300 1 201 1.1E-27 T 29-03-2018 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Pfam PF14535 AMP-binding enzyme C-terminal domain 444 536 1.2E-6 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Gene3D G3DSA:2.30.38.10 345 434 1.9E-15 T 29-03-2018 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 SUPERFAMILY SSF56801 23 537 1.44E-94 T 29-03-2018 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Pfam PF00501 AMP-binding enzyme 21 442 1.7E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Gene3D G3DSA:3.40.50.980 160 329 9.1E-35 T 29-03-2018 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Gene3D G3DSA:3.40.50.980 4 159 1.2E-22 T 29-03-2018 MSG_RS19925 e788943b6139c9401a5792bbcc0847b4 544 Gene3D G3DSA:3.30.300.30 435 540 6.7E-14 T 29-03-2018 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 243 258 1.3E-16 T 29-03-2018 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.3E-16 T 29-03-2018 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 133 148 1.3E-16 T 29-03-2018 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 SUPERFAMILY SSF51905 230 306 1.24E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 SUPERFAMILY SSF51905 4 154 1.24E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 Pfam PF01494 FAD binding domain 103 167 1.1E-7 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS19255 3a3c9ae7802de508e721342851fbcc55 337 Gene3D G3DSA:3.50.50.60 3 310 2.6E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 SUPERFAMILY SSF52141 8 162 2.09E-34 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 Gene3D G3DSA:3.40.470.10 5 163 1.7E-43 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 Pfam PF03167 Uracil DNA glycosylase superfamily 11 159 2.5E-6 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 SMART SM00986 10 162 2.7E-9 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 SMART SM00987 10 162 2.7E-9 T 29-03-2018 MSG_RS18575 dc9457b7d285ce58bac7e0b41e461ad2 163 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 8 158 1.8E-45 T 29-03-2018 IPR026353 Hypoxanthine-DNA glycosylase MSG_RS06935 15f3d1dd678954e4e9122fa06f5d3d70 468 Gene3D G3DSA:3.30.70.1230 291 468 4.0E-36 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS06935 15f3d1dd678954e4e9122fa06f5d3d70 468 SMART SM00044 267 443 6.7E-7 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS06935 15f3d1dd678954e4e9122fa06f5d3d70 468 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 296 463 1.6E-25 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS06935 15f3d1dd678954e4e9122fa06f5d3d70 468 SUPERFAMILY SSF55073 297 467 1.08E-39 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS17015 0c56a3219b6d81dea4a5ea71d158a1cd 132 SUPERFAMILY SSF81301 7 118 3.92E-38 T 29-03-2018 MSG_RS17015 0c56a3219b6d81dea4a5ea71d158a1cd 132 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 1.9E-24 T 29-03-2018 MSG_RS17015 0c56a3219b6d81dea4a5ea71d158a1cd 132 Gene3D G3DSA:3.30.460.10 4 112 9.3E-32 T 29-03-2018 MSG_RS17015 0c56a3219b6d81dea4a5ea71d158a1cd 132 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 108 5.7E-32 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MSG_RS17015 0c56a3219b6d81dea4a5ea71d158a1cd 132 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 22.902 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 ProSitePatterns PS00571 Amidases signature. 184 215 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 42 517 89.721 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 Pfam PF01425 Amidase 55 505 1.6E-156 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 Gene3D G3DSA:3.90.1300.10 32 518 9.2E-159 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 SUPERFAMILY SSF75304 28 516 6.93E-154 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS07715 6edc9ba5bc7abe74a1f27e7c2c811f63 523 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 44 515 3.5E-190 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS18290 70308a3a9a738dedbb8cc216ca47ba1d 217 Gene3D G3DSA:3.90.870.10 1 212 5.0E-66 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS18290 70308a3a9a738dedbb8cc216ca47ba1d 217 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 208 1.6E-66 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MSG_RS18290 70308a3a9a738dedbb8cc216ca47ba1d 217 Pfam PF01300 Telomere recombination 23 197 2.7E-44 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MSG_RS18290 70308a3a9a738dedbb8cc216ca47ba1d 217 SUPERFAMILY SSF55821 3 208 6.1E-56 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MSG_RS07060 f05ff2d2db95399062499db7899461d4 208 SMART SM01006 37 84 2.3E-17 T 29-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain MSG_RS07060 f05ff2d2db95399062499db7899461d4 208 SUPERFAMILY SSF55729 5 197 4.61E-50 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS07060 f05ff2d2db95399062499db7899461d4 208 Pfam PF13523 Acetyltransferase (GNAT) domain 40 185 9.0E-41 T 29-03-2018 MSG_RS07060 f05ff2d2db95399062499db7899461d4 208 Gene3D G3DSA:3.40.630.30 3 201 8.0E-29 T 29-03-2018 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 44 422 1.6E-110 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 SUPERFAMILY SSF51735 44 181 1.64E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 45 419 44.005 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 SUPERFAMILY SSF69055 324 420 3.4E-24 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Gene3D G3DSA:1.10.1740.10 334 424 4.4E-27 T 29-03-2018 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 SUPERFAMILY SSF55347 159 295 1.6E-52 T 29-03-2018 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 PIRSF PIRSF006205 42 425 2.8E-134 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Pfam PF13288 DXP reductoisomerase C-terminal domain 293 414 3.6E-33 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 177 260 3.3E-33 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Gene3D G3DSA:3.40.50.720 41 181 8.1E-46 T 29-03-2018 MSG_RS08395 a2e3c9d641ba0867636058d2eb33c870 428 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 45 165 4.8E-37 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MSG_RS22285 46c47aaa00f4a7ba4358fd22840a4ad1 280 Pfam PF02405 Permease MlaE 64 267 1.3E-51 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS07510 7870e6e3cb4729b6f0bf248db6fcb6f0 444 SUPERFAMILY SSF50998 96 197 4.87E-18 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MSG_RS07510 7870e6e3cb4729b6f0bf248db6fcb6f0 444 SUPERFAMILY SSF50998 272 441 4.87E-18 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MSG_RS07510 7870e6e3cb4729b6f0bf248db6fcb6f0 444 Gene3D G3DSA:2.140.10.10 384 444 0.012 T 29-03-2018 MSG_RS07510 7870e6e3cb4729b6f0bf248db6fcb6f0 444 Gene3D G3DSA:2.140.10.10 35 383 5.6E-26 T 29-03-2018 MSG_RS07510 7870e6e3cb4729b6f0bf248db6fcb6f0 444 Pfam PF13360 PQQ-like domain 283 422 1.3E-6 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MSG_RS18935 23221f5d3b7dcd6ba93c75ba14247c2f 486 Gene3D G3DSA:3.40.309.10 271 467 5.1E-64 T 29-03-2018 MSG_RS18935 23221f5d3b7dcd6ba93c75ba14247c2f 486 SUPERFAMILY SSF53720 7 480 1.83E-144 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS18935 23221f5d3b7dcd6ba93c75ba14247c2f 486 Pfam PF00171 Aldehyde dehydrogenase family 19 480 1.7E-148 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS18935 23221f5d3b7dcd6ba93c75ba14247c2f 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS18935 23221f5d3b7dcd6ba93c75ba14247c2f 486 Gene3D G3DSA:3.40.605.10 2 270 4.3E-77 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS12325 966183c134932a60dc51e6c3afcb451e 319 SUPERFAMILY SSF53474 20 304 1.28E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12325 966183c134932a60dc51e6c3afcb451e 319 Gene3D G3DSA:3.40.50.1820 3 317 1.2E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12325 966183c134932a60dc51e6c3afcb451e 319 Pfam PF07859 alpha/beta hydrolase fold 81 288 7.7E-72 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 SMART SM00829 13 360 3.0E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 Gene3D G3DSA:3.40.50.10730 171 303 3.6E-33 T 29-03-2018 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 SUPERFAMILY SSF51735 150 326 1.35E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 Pfam PF00107 Zinc-binding dehydrogenase 188 312 2.0E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 SUPERFAMILY SSF50129 310 359 2.73E-7 T 29-03-2018 IPR011032 GroES-like MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 SUPERFAMILY SSF50129 3 184 2.59E-51 T 29-03-2018 IPR011032 GroES-like MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 Gene3D G3DSA:3.90.180.10 5 170 3.7E-42 T 29-03-2018 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 147 1.6E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS10030 197610a4a1add1f8661473f27172d82c 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 360 2.5E-201 T 29-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Pfam PF00069 Protein kinase domain 172 363 5.8E-32 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Pfam PF16919 Protein kinase G rubredoxin domain 31 171 4.5E-57 T 29-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Gene3D G3DSA:1.25.40.10 408 610 4.8E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 SUPERFAMILY SSF56112 149 412 9.99E-46 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Gene3D G3DSA:1.10.510.10 259 407 3.1E-25 T 29-03-2018 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 SUPERFAMILY SSF48452 528 596 7.05E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 SMART SM00220 172 416 7.9E-25 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Gene3D G3DSA:3.30.200.20 163 258 1.9E-14 T 29-03-2018 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 295 307 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MSG_RS02995 c05af8ac0b40cd1b6690aed7e04a812b 773 Pfam PF16918 Protein kinase G tetratricopeptide repeat 432 771 9.2E-151 T 29-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS04790 820330b1250d897d39401c4fbb4dff6c 207 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 180 3.0E-49 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS04790 820330b1250d897d39401c4fbb4dff6c 207 Gene3D G3DSA:2.60.120.10 1 193 6.2E-68 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS04790 820330b1250d897d39401c4fbb4dff6c 207 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 179 3.6E-63 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS04790 820330b1250d897d39401c4fbb4dff6c 207 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 196 2.0E-94 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MSG_RS04790 820330b1250d897d39401c4fbb4dff6c 207 SUPERFAMILY SSF51182 1 196 1.6E-73 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS11855 ca0f13d4c776707c962c541ff164e0b7 190 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 29 147 3.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS11855 ca0f13d4c776707c962c541ff164e0b7 190 Pfam PF13419 Haloacid dehalogenase-like hydrolase 47 147 2.5E-17 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11855 ca0f13d4c776707c962c541ff164e0b7 190 Gene3D G3DSA:3.40.50.1000 30 175 3.8E-22 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11855 ca0f13d4c776707c962c541ff164e0b7 190 SUPERFAMILY SSF56784 23 161 2.51E-27 T 29-03-2018 IPR023214 HAD-like domain MSG_RS21630 0ffa1a7a22343148efe3ecfb939e69a9 267 TIGRFAM TIGR04255 sporadTIGR04255: TIGR04255 family protein 12 264 5.6E-47 T 29-03-2018 IPR026349 Conserved hypothetical protein CHP04255 MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 327 9.6E-73 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 Gene3D G3DSA:3.40.50.1100 47 154 1.0E-27 T 29-03-2018 MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 TIGRFAM TIGR00260 thrC: threonine synthase 17 334 9.9E-93 T 29-03-2018 IPR004450 Threonine synthase-like MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 SUPERFAMILY SSF53686 10 341 1.13E-104 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 60 73 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 PIRSF PIRSF038945 1 359 1.3E-178 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 MSG_RS18325 1d75c874efa7e915fd78b29895f4e0d6 360 Gene3D G3DSA:3.40.50.1100 155 343 4.2E-48 T 29-03-2018 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 Gene3D G3DSA:3.40.47.10 1 250 1.4E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 PIRSF PIRSF000429 1 403 2.2E-55 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 Pfam PF00108 Thiolase, N-terminal domain 13 235 6.6E-9 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 SUPERFAMILY SSF53901 203 386 3.13E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 SUPERFAMILY SSF53901 19 127 3.13E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 Gene3D G3DSA:3.40.47.10 261 403 1.6E-12 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20590 852b3561c70a564670e5bd52cab94ff9 408 Pfam PF02803 Thiolase, C-terminal domain 281 381 6.5E-10 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 Gene3D G3DSA:3.40.47.10 12 109 7.1E-4 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 SUPERFAMILY SSF53901 254 359 1.1E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 Gene3D G3DSA:3.40.47.10 134 379 2.0E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 Pfam PF00108 Thiolase, N-terminal domain 5 174 4.7E-14 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 Pfam PF02803 Thiolase, C-terminal domain 253 353 1.5E-8 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 PIRSF PIRSF000429 1 380 8.5E-42 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS20880 a22a63104f316d21a0b5acc80c63b3d6 381 SUPERFAMILY SSF53901 4 220 6.08E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 Gene3D G3DSA:3.40.718.10 417 717 1.0E-36 T 29-03-2018 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 Gene3D G3DSA:3.40.718.10 60 368 6.7E-43 T 29-03-2018 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 2 742 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 PIRSF PIRSF009407 1 744 0.0 T 29-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MSG_RS05375 8583dd9f7ee8a57575e5a415ed423b93 745 SUPERFAMILY SSF53659 5 741 0.0 T 29-03-2018 MSG_RS01055 2621bd7007bd1345b9ed304f9fd118b7 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 1.1E-22 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01055 2621bd7007bd1345b9ed304f9fd118b7 54 Pfam PF00471 Ribosomal protein L33 9 54 4.5E-17 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01055 2621bd7007bd1345b9ed304f9fd118b7 54 SUPERFAMILY SSF57829 4 54 3.3E-17 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MSG_RS01055 2621bd7007bd1345b9ed304f9fd118b7 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.505 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS01055 2621bd7007bd1345b9ed304f9fd118b7 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS01010 70a8d5fef83e5fea44bcfd2e4f25df65 151 Gene3D G3DSA:3.30.530.20 2 150 1.2E-19 T 29-03-2018 IPR023393 START-like domain MSG_RS01010 70a8d5fef83e5fea44bcfd2e4f25df65 151 SUPERFAMILY SSF55961 6 148 3.17E-18 T 29-03-2018 MSG_RS01010 70a8d5fef83e5fea44bcfd2e4f25df65 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 146 6.2E-8 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS21190 4b19e9df5d5ad2a21c913a749e0309c5 269 Pfam PF03988 Repeat of Unknown Function (DUF347) 73 122 4.2E-13 T 29-03-2018 IPR007136 Protein of unknown function DUF347 MSG_RS21190 4b19e9df5d5ad2a21c913a749e0309c5 269 Pfam PF03988 Repeat of Unknown Function (DUF347) 138 188 4.8E-16 T 29-03-2018 IPR007136 Protein of unknown function DUF347 MSG_RS21190 4b19e9df5d5ad2a21c913a749e0309c5 269 Pfam PF03988 Repeat of Unknown Function (DUF347) 193 242 1.8E-12 T 29-03-2018 IPR007136 Protein of unknown function DUF347 MSG_RS21190 4b19e9df5d5ad2a21c913a749e0309c5 269 Pfam PF03988 Repeat of Unknown Function (DUF347) 19 69 2.5E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 MSG_RS17485 efaf8d56d6f6e81c38ede76124be2d09 447 Gene3D G3DSA:1.20.1250.20 8 238 1.5E-8 T 29-03-2018 MSG_RS17485 efaf8d56d6f6e81c38ede76124be2d09 447 Gene3D G3DSA:1.20.1250.20 242 436 1.0E-18 T 29-03-2018 MSG_RS17485 efaf8d56d6f6e81c38ede76124be2d09 447 SUPERFAMILY SSF103473 37 438 9.42E-31 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS17485 efaf8d56d6f6e81c38ede76124be2d09 447 Pfam PF11700 Vacuole effluxer Atg22 like 66 435 6.1E-22 T 29-03-2018 IPR024671 Autophagy-related protein 22-like MSG_RS06780 f3b4f6b3cac6ad64db6c1fb9430aabfb 143 SMART SM00867 3 139 3.4E-10 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS06780 f3b4f6b3cac6ad64db6c1fb9430aabfb 143 Pfam PF04264 YceI-like domain 5 129 4.9E-19 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS06780 f3b4f6b3cac6ad64db6c1fb9430aabfb 143 SUPERFAMILY SSF101874 3 140 2.22E-23 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS06780 f3b4f6b3cac6ad64db6c1fb9430aabfb 143 Gene3D G3DSA:2.40.128.110 1 142 6.6E-27 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MSG_RS20035 003d7d2ad35f449fe9ca0c0a594eb760 337 Gene3D G3DSA:3.40.50.2000 157 316 7.1E-25 T 29-03-2018 MSG_RS20035 003d7d2ad35f449fe9ca0c0a594eb760 337 SUPERFAMILY SSF53756 4 332 9.42E-44 T 29-03-2018 MSG_RS20035 003d7d2ad35f449fe9ca0c0a594eb760 337 Pfam PF13692 Glycosyl transferases group 1 166 297 4.7E-17 T 29-03-2018 MSG_RS11175 70aed523f20e7b4a2f6f0a639032250f 244 Pfam PF00977 Histidine biosynthesis protein 5 234 9.3E-59 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MSG_RS11175 70aed523f20e7b4a2f6f0a639032250f 244 SUPERFAMILY SSF51366 3 240 7.85E-59 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MSG_RS11175 70aed523f20e7b4a2f6f0a639032250f 244 Gene3D G3DSA:3.20.20.70 4 244 3.2E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS11175 70aed523f20e7b4a2f6f0a639032250f 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 1 243 4.4E-135 T 29-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 MSG_RS11175 70aed523f20e7b4a2f6f0a639032250f 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 31.261 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MSG_RS05285 84e0ffd3669b97485d16536388907b21 185 Pfam PF13599 Pentapeptide repeats (9 copies) 48 120 2.5E-12 T 29-03-2018 IPR001646 Pentapeptide repeat MSG_RS05285 84e0ffd3669b97485d16536388907b21 185 SUPERFAMILY SSF141571 3 178 8.44E-46 T 29-03-2018 MSG_RS05285 84e0ffd3669b97485d16536388907b21 185 Gene3D G3DSA:2.160.20.80 2 182 8.0E-36 T 29-03-2018 MSG_RS05285 84e0ffd3669b97485d16536388907b21 185 Pfam PF00805 Pentapeptide repeats (8 copies) 6 39 0.0093 T 29-03-2018 IPR001646 Pentapeptide repeat MSG_RS00640 0ac3413b3fa5945ce2a3bd317e0a2406 319 SUPERFAMILY SSF53474 56 311 3.11E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00640 0ac3413b3fa5945ce2a3bd317e0a2406 319 Gene3D G3DSA:3.40.50.1820 64 318 2.0E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00640 0ac3413b3fa5945ce2a3bd317e0a2406 319 Pfam PF00561 alpha/beta hydrolase fold 71 206 4.9E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS14815 7ee7fe99a7c73c7801bb01d495c3054a 93 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 7 93 17.981 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MSG_RS14815 7ee7fe99a7c73c7801bb01d495c3054a 93 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 6.1E-9 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MSG_RS14815 7ee7fe99a7c73c7801bb01d495c3054a 93 Gene3D G3DSA:1.10.287.1080 1 93 3.2E-15 T 29-03-2018 MSG_RS14815 7ee7fe99a7c73c7801bb01d495c3054a 93 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 11 93 1.1E-22 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MSG_RS14815 7ee7fe99a7c73c7801bb01d495c3054a 93 SUPERFAMILY SSF101386 8 93 5.23E-21 T 29-03-2018 MSG_RS05485 59880ab6f92072ddf907de0134c8a085 133 SUPERFAMILY SSF53927 5 128 3.01E-39 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MSG_RS05485 59880ab6f92072ddf907de0134c8a085 133 Gene3D G3DSA:3.40.140.10 3 131 6.9E-39 T 29-03-2018 MSG_RS05485 59880ab6f92072ddf907de0134c8a085 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 102 4.9E-12 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MSG_RS00665 91d5a41f4d9727d7acbc593d37cf7eb2 434 Gene3D G3DSA:3.20.20.30 1 434 1.9E-88 T 29-03-2018 MSG_RS00665 91d5a41f4d9727d7acbc593d37cf7eb2 434 SUPERFAMILY SSF51679 5 428 4.45E-108 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00665 91d5a41f4d9727d7acbc593d37cf7eb2 434 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 11 422 4.4E-131 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00665 91d5a41f4d9727d7acbc593d37cf7eb2 434 PIRSF PIRSF000337 2 434 5.4E-134 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS00665 91d5a41f4d9727d7acbc593d37cf7eb2 434 Pfam PF00296 Luciferase-like monooxygenase 18 377 2.7E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04890 30456249826a6594be6ec168a9271d55 413 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 266 411 4.0E-38 T 29-03-2018 IPR023840 Type VII secretion system Rv3446c MSG_RS16150 7f5a103ccb73cf3f603b7adc96b26af8 205 Gene3D G3DSA:1.20.120.450 1 180 1.7E-19 T 29-03-2018 MSG_RS16150 7f5a103ccb73cf3f603b7adc96b26af8 205 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 137 3.8E-6 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MSG_RS16150 7f5a103ccb73cf3f603b7adc96b26af8 205 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 182 8.9E-36 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS16150 7f5a103ccb73cf3f603b7adc96b26af8 205 SUPERFAMILY SSF109854 6 111 1.1E-6 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS16150 7f5a103ccb73cf3f603b7adc96b26af8 205 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 4 198 2.4E-73 T 29-03-2018 IPR017519 Conserved hypothetical protein CHP03085 MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 Pfam PF07969 Amidohydrolase family 49 540 6.4E-45 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 Gene3D G3DSA:3.20.20.140 69 498 1.2E-37 T 29-03-2018 MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 Gene3D G3DSA:2.30.40.10 1 68 1.0E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 SUPERFAMILY SSF51556 59 105 2.59E-20 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 SUPERFAMILY SSF51556 206 500 2.59E-20 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS07925 26b20f077b740a3f36090ab3f4cfaefb 569 SUPERFAMILY SSF51338 2 71 2.16E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS01245 2cdb1948bd84b053c6bccbdf1739547d 450 Gene3D G3DSA:3.90.1200.10 243 431 1.7E-15 T 29-03-2018 MSG_RS01245 2cdb1948bd84b053c6bccbdf1739547d 450 SUPERFAMILY SSF56112 137 432 1.75E-17 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS19225 30e4367bfec1d365359b1ea410e716ac 272 SUPERFAMILY SSF52096 15 268 9.65E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS19225 30e4367bfec1d365359b1ea410e716ac 272 Gene3D G3DSA:3.90.226.10 15 227 8.8E-56 T 29-03-2018 MSG_RS19225 30e4367bfec1d365359b1ea410e716ac 272 Gene3D G3DSA:1.10.12.10 228 270 3.7E-12 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS19225 30e4367bfec1d365359b1ea410e716ac 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 269 2.0E-52 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 SUPERFAMILY SSF56014 276 360 2.22E-11 T 29-03-2018 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 32.924 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 Gene3D G3DSA:3.20.20.120 25 159 7.3E-19 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 Pfam PF04551 GcpE protein 21 361 5.6E-131 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 Gene3D G3DSA:3.20.20.70 160 373 0.27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 PIRSF PIRSF004640 11 372 1.9E-143 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 2.1E-125 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MSG_RS08405 4e00c76cf4dbf433f1d2d6564d6eedf7 392 SUPERFAMILY SSF51717 46 219 8.63E-10 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS11910 3231a09af09ebccbaad95d3242e4638d 303 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 257 5.0E-61 T 29-03-2018 MSG_RS11910 3231a09af09ebccbaad95d3242e4638d 303 ProSitePatterns PS00161 Isocitrate lyase signature. 123 128 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS11910 3231a09af09ebccbaad95d3242e4638d 303 SUPERFAMILY SSF51621 8 293 1.75E-87 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS11910 3231a09af09ebccbaad95d3242e4638d 303 Gene3D G3DSA:3.20.20.60 5 298 2.0E-82 T 29-03-2018 MSG_RS14000 d23836574b25184f3d3e8825729d631b 111 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 110 3.8E-30 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MSG_RS14000 d23836574b25184f3d3e8825729d631b 111 PIRSF PIRSF004761 1 111 1.4E-24 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Gene3D G3DSA:1.10.540.10 1 115 4.4E-34 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 SUPERFAMILY SSF56645 1 224 9.42E-66 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 213 2.1E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 SUPERFAMILY SSF47203 227 377 4.67E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 PIRSF PIRSF016578 1 188 1.9E-9 T 29-03-2018 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 PIRSF PIRSF016578 222 378 4.8E-8 T 29-03-2018 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Gene3D G3DSA:1.20.140.10 218 380 4.9E-51 T 29-03-2018 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 1.1E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Gene3D G3DSA:2.40.110.10 116 217 1.5E-32 T 29-03-2018 MSG_RS01975 c0e6a6fe86c042af4302f319b9016127 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 113 4.8E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 192 5.9E-60 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 3.8E-14 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 3.8E-14 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 3.8E-14 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 SUPERFAMILY SSF52317 1 195 3.25E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 Gene3D G3DSA:3.40.50.880 1 197 1.5E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 53 62 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 126 138 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 171 184 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 106 114 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.1E-35 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 8.5E-10 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 8.5E-10 T 29-03-2018 MSG_RS00095 1209a62339bf548594b75fff9f54acd0 231 Pfam PF00117 Glutamine amidotransferase class-I 5 191 1.0E-49 T 29-03-2018 IPR017926 Glutamine amidotransferase MSG_RS08230 ab9a94570568aab536e35763fcea53e8 243 SUPERFAMILY SSF53098 21 216 1.03E-59 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS08230 ab9a94570568aab536e35763fcea53e8 243 Pfam PF01351 Ribonuclease HII 33 212 7.3E-44 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain MSG_RS08230 ab9a94570568aab536e35763fcea53e8 243 Hamap MF_00052_B Ribonuclease HII [rnhB]. 31 212 37.593 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 MSG_RS08230 ab9a94570568aab536e35763fcea53e8 243 Gene3D G3DSA:3.30.420.10 9 229 8.1E-59 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS02925 b14f7a3679793cfa77809064788d7fa9 123 Pfam PF11255 Protein of unknown function (DUF3054) 11 112 1.2E-33 T 29-03-2018 IPR021414 Protein of unknown function DUF3054 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 Gene3D G3DSA:3.90.1510.10 66 177 8.3E-34 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 Gene3D G3DSA:3.90.1510.10 178 276 2.5E-25 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 PIRSF PIRSF006078 176 376 1.8E-50 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 PIRSF PIRSF006078 25 177 1.0E-42 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 Pfam PF02595 Glycerate kinase family 178 372 4.7E-50 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 Pfam PF02595 Glycerate kinase family 27 175 7.3E-44 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MSG_RS15360 08bb5f673d42bdd697a037987a8d3fe9 382 SUPERFAMILY SSF110738 25 372 1.44E-85 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 TIGRFAM TIGR00833 actII: transport protein 22 929 1.3E-296 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 Gene3D G3DSA:1.20.1640.10 715 926 6.5E-25 T 29-03-2018 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 Gene3D G3DSA:1.10.287.950 456 565 0.041 T 29-03-2018 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 Pfam PF03176 MMPL family 53 382 2.4E-104 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 Pfam PF03176 MMPL family 605 951 8.4E-92 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 Gene3D G3DSA:1.20.1640.10 144 366 5.5E-28 T 29-03-2018 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 SUPERFAMILY SSF82866 153 350 2.49E-25 T 29-03-2018 MSG_RS15140 64aeba79ba13d3a88da2c16030503bbd 972 SUPERFAMILY SSF82866 720 929 7.32E-29 T 29-03-2018 MSG_RS20090 22ebd47ead2fb5f675a5c95a39f6a912 520 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 326 519 1.8E-17 T 29-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 MSG_RS20090 22ebd47ead2fb5f675a5c95a39f6a912 520 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 116 295 4.0E-15 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 MSG_RS03130 336fd6b5935e247971304a3146eb8908 102 Pfam PF11662 Protein of unknown function (DUF3263) 21 92 1.2E-35 T 29-03-2018 IPR021678 Protein of unknown function DUF3263 MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 315 470 1.0E-69 T 29-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 Pfam PF06114 IrrE N-terminal-like domain 192 314 2.5E-25 T 29-03-2018 IPR010359 IrrE N-terminal-like domain MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 SUPERFAMILY SSF47413 5 71 5.07E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 SMART SM00530 12 67 3.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 Gene3D G3DSA:1.10.260.40 1 82 2.6E-15 T 29-03-2018 MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 PIRSF PIRSF019251 1 475 4.1E-198 T 29-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 MSG_RS03355 40655ef5d8a931fa2d7ca3b02131e810 475 Pfam PF12844 Helix-turn-helix domain 10 68 4.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 134 147 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 74 89 1.3E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 SUPERFAMILY SSF53474 15 296 1.42E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 Pfam PF00561 alpha/beta hydrolase fold 49 170 9.4E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00412 Epoxide hydrolase signature 274 296 2.6E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00412 Epoxide hydrolase signature 120 133 2.6E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00412 Epoxide hydrolase signature 54 72 2.6E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 PRINTS PR00412 Epoxide hydrolase signature 74 89 2.6E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 Hamap MF_01230 Haloalkane dehalogenase [dhmA]. 1 298 49.1 T 29-03-2018 IPR023489 Haloalkane dehalogenase, subfamily 1 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 MSG_RS02910 c7603bf67b83937c836b826e142cbd84 301 Gene3D G3DSA:3.40.50.1820 1 299 4.3E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS23985 3abf2d889e1c600ba6d1ee5de228d7c8 152 Pfam PF14231 GXWXG protein 24 82 1.8E-23 T 29-03-2018 IPR025951 GXWXG domain MSG_RS23985 3abf2d889e1c600ba6d1ee5de228d7c8 152 Pfam PF14232 Domain of unknown function (DUF4334) 93 151 8.7E-29 T 29-03-2018 IPR025568 Domain of unknown function DUF4334 MSG_RS00035 65b72552c938aba49fff93b2f97a3e4b 286 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 169 284 3.6E-41 T 29-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane MSG_RS20495 771354bf95553ee058048e2a11d9065d 358 Gene3D G3DSA:3.40.50.720 1 184 2.0E-16 T 29-03-2018 MSG_RS20495 771354bf95553ee058048e2a11d9065d 358 SUPERFAMILY SSF51735 1 159 2.76E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02900 5b6318162e63c1dd10ad16e4acad766e 178 SUPERFAMILY SSF46689 2 70 1.64E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS02900 5b6318162e63c1dd10ad16e4acad766e 178 Gene3D G3DSA:1.10.260.40 29 124 3.2E-7 T 29-03-2018 MSG_RS02900 5b6318162e63c1dd10ad16e4acad766e 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 39 1.5E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS02900 5b6318162e63c1dd10ad16e4acad766e 178 Gene3D G3DSA:1.10.10.60 1 28 3.6E-7 T 29-03-2018 MSG_RS03145 937eefb3fc676589bd243c25709fa418 379 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 24 300 6.9E-86 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS03145 937eefb3fc676589bd243c25709fa418 379 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 22 305 1.9E-113 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS03145 937eefb3fc676589bd243c25709fa418 379 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 379 103.8 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MSG_RS03145 937eefb3fc676589bd243c25709fa418 379 SUPERFAMILY SSF55931 13 377 9.81E-113 T 29-03-2018 MSG_RS03920 8bab6868a66f4cfa7dc740c989297adb 167 SUPERFAMILY SSF109854 40 158 3.43E-18 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS03920 8bab6868a66f4cfa7dc740c989297adb 167 Gene3D G3DSA:1.20.120.450 14 163 2.2E-11 T 29-03-2018 MSG_RS03920 8bab6868a66f4cfa7dc740c989297adb 167 Pfam PF12867 DinB superfamily 32 159 9.6E-10 T 29-03-2018 IPR024775 DinB-like domain MSG_RS22870 aac99fb72ab57bdc1a9503d9993d5349 138 Gene3D G3DSA:3.10.180.10 1 137 1.0E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22870 aac99fb72ab57bdc1a9503d9993d5349 138 SUPERFAMILY SSF54593 2 137 5.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22870 aac99fb72ab57bdc1a9503d9993d5349 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 133 6.9E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS12200 6d44cf1a400b3bc8791588aeeea004b1 302 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 265 5.0E-22 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS12200 6d44cf1a400b3bc8791588aeeea004b1 302 Gene3D G3DSA:3.10.180.10 2 131 3.3E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS12200 6d44cf1a400b3bc8791588aeeea004b1 302 Gene3D G3DSA:3.10.180.10 133 299 5.6E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS12200 6d44cf1a400b3bc8791588aeeea004b1 302 SUPERFAMILY SSF54593 4 275 1.51E-37 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS12200 6d44cf1a400b3bc8791588aeeea004b1 302 TIGRFAM TIGR03213 23dbph12diox: 2,3-dihydroxybiphenyl 1,2-dioxygenase 5 292 3.7E-113 T 29-03-2018 IPR017626 2,3-dihydroxybiphenyl 1,2-dioxygenase GO:0005506|GO:0042178|GO:0051213|GO:0055114 MSG_RS09380 157e070d46a72b77ea4bd92a30b4ccf2 123 Pfam PF05305 Protein of unknown function (DUF732) 9 99 3.4E-16 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS24285 175dd7248de3bc6a0e168b2509593d70 116 SUPERFAMILY SSF55486 3 115 3.67E-37 T 29-03-2018 MSG_RS24285 175dd7248de3bc6a0e168b2509593d70 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 8.3E-33 T 29-03-2018 IPR010428 Zincin-like metallopeptidase MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 SUPERFAMILY SSF48452 22 135 5.69E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 Gene3D G3DSA:1.10.10.10 127 218 2.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 Gene3D G3DSA:1.10.10.10 89 126 0.025 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 Gene3D G3DSA:1.10.10.10 17 88 6.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 Gene3D G3DSA:1.10.10.10 331 429 2.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12275 869e040c26e1790046b08ffaa700aa51 448 Pfam PF13374 Tetratricopeptide repeat 151 192 3.1E-5 T 29-03-2018 MSG_RS01590 c983ecaffdba4b60c4f502ba683ff402 166 Pfam PF12802 MarR family 49 97 1.5E-7 T 29-03-2018 MSG_RS01590 c983ecaffdba4b60c4f502ba683ff402 166 Gene3D G3DSA:1.10.10.10 2 148 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01590 c983ecaffdba4b60c4f502ba683ff402 166 SUPERFAMILY SSF46785 11 144 1.62E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01590 c983ecaffdba4b60c4f502ba683ff402 166 SMART SM00347 31 134 2.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 Gene3D G3DSA:3.30.110.70 34 122 5.5E-19 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 Gene3D G3DSA:3.30.110.70 152 243 2.4E-18 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 SUPERFAMILY SSF117782 39 124 5.23E-15 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 SUPERFAMILY SSF117782 156 244 1.26E-16 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 Pfam PF01906 Putative heavy-metal-binding 160 243 2.8E-9 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 MSG_RS12475 29555f04fc60d491a8589d1dc0917f6b 261 Pfam PF01906 Putative heavy-metal-binding 64 121 8.1E-11 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 SUPERFAMILY SSF51735 151 448 4.47E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 Gene3D G3DSA:3.40.50.720 148 437 7.9E-31 T 29-03-2018 MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 Pfam PF01370 NAD dependent epimerase/dehydratase family 156 360 8.1E-8 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 Gene3D G3DSA:3.30.530.20 2 147 4.3E-25 T 29-03-2018 IPR023393 START-like domain MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 SUPERFAMILY SSF55961 3 139 5.96E-16 T 29-03-2018 MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 155 443 2.3E-89 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 MSG_RS07605 49d9dffbd989b95e4cbb7e6cd46ce74d 451 Pfam PF08338 Domain of unknown function (DUF1731) 398 446 3.0E-14 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 MSG_RS19035 532e38d16c3bfefc293ff2dc1737d4c0 375 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 253 353 6.0E-9 T 29-03-2018 MSG_RS19035 532e38d16c3bfefc293ff2dc1737d4c0 375 Pfam PF03601 Conserved hypothetical protein 698 30 347 1.5E-94 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 MSG_RS15570 3de92ba4490e170dacf592503f123e61 283 SUPERFAMILY SSF53474 18 282 7.83E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15570 3de92ba4490e170dacf592503f123e61 283 Gene3D G3DSA:3.40.50.1820 7 282 1.2E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15570 3de92ba4490e170dacf592503f123e61 283 Pfam PF12697 Alpha/beta hydrolase family 25 273 1.0E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 Gene3D G3DSA:3.90.550.10 6 243 1.9E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 Gene3D G3DSA:2.160.10.10 244 353 6.7E-19 T 29-03-2018 MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 SUPERFAMILY SSF53448 268 307 6.1E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 SUPERFAMILY SSF53448 8 240 6.1E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 Pfam PF00483 Nucleotidyl transferase 9 234 2.2E-43 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MSG_RS05810 310edda3d2ba2fe17ea58fec7b365bc4 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 304 335 7.6E-4 T 29-03-2018 IPR001451 Hexapeptide repeat MSG_RS24135 8e890b14ed4e2964d4868a575c9e4602 108 Pfam PF00498 FHA domain 31 93 4.7E-19 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS24135 8e890b14ed4e2964d4868a575c9e4602 108 SUPERFAMILY SSF49879 9 100 3.63E-29 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS24135 8e890b14ed4e2964d4868a575c9e4602 108 SMART SM00240 29 79 6.3E-13 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS24135 8e890b14ed4e2964d4868a575c9e4602 108 Gene3D G3DSA:2.60.200.20 2 102 6.1E-28 T 29-03-2018 MSG_RS11260 cf824ce488e8722c229fa80b4c49386e 301 Gene3D G3DSA:3.10.129.10 140 296 9.2E-42 T 29-03-2018 MSG_RS11260 cf824ce488e8722c229fa80b4c49386e 301 Pfam PF13622 Thioesterase-like superfamily 38 293 6.3E-44 T 29-03-2018 MSG_RS11260 cf824ce488e8722c229fa80b4c49386e 301 SUPERFAMILY SSF54637 129 293 1.49E-39 T 29-03-2018 IPR029069 HotDog domain MSG_RS11260 cf824ce488e8722c229fa80b4c49386e 301 Gene3D G3DSA:3.10.129.10 10 124 3.8E-25 T 29-03-2018 MSG_RS11260 cf824ce488e8722c229fa80b4c49386e 301 SUPERFAMILY SSF54637 17 127 1.28E-25 T 29-03-2018 IPR029069 HotDog domain MSG_RS08680 cafdb45a05b8a113e484077b0e43c501 130 Pfam PF05305 Protein of unknown function (DUF732) 35 130 1.9E-10 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS10395 cbe6af53890e403e48c1b2c30c7a48bf 358 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 314 2.2E-101 T 29-03-2018 IPR010119 Gluconeogenesis factor MSG_RS10395 cbe6af53890e403e48c1b2c30c7a48bf 358 Pfam PF01933 Uncharacterised protein family UPF0052 9 283 8.9E-69 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 MSG_RS10395 cbe6af53890e403e48c1b2c30c7a48bf 358 Gene3D G3DSA:3.40.50.10680 88 315 1.0E-49 T 29-03-2018 MSG_RS10395 cbe6af53890e403e48c1b2c30c7a48bf 358 SUPERFAMILY SSF142338 7 311 2.88E-82 T 29-03-2018 MSG_RS10395 cbe6af53890e403e48c1b2c30c7a48bf 358 Hamap MF_00973 Gluconeogenesis factor. 5 317 31.781 T 29-03-2018 IPR010119 Gluconeogenesis factor MSG_RS03380 e9df707bea6dc3d05966c91482369c37 287 Gene3D G3DSA:3.40.50.150 1 287 1.5E-59 T 29-03-2018 MSG_RS03380 e9df707bea6dc3d05966c91482369c37 287 SUPERFAMILY SSF53335 13 287 1.24E-75 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03380 e9df707bea6dc3d05966c91482369c37 287 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 283 2.0E-118 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03380 e9df707bea6dc3d05966c91482369c37 287 PIRSF PIRSF003085 2 287 5.5E-113 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS24280 1a490bb4ff5cf01f5c47bad409221600 452 Pfam PF13845 Septum formation 97 321 1.3E-75 T 29-03-2018 IPR026004 Septum formation-related domain MSG_RS08880 ad66eca3d891cb0f78506e7e76583156 226 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 197 216 1.0E-7 T 29-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 SMART SM01211 2 221 9.9E-119 T 29-03-2018 MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 SUPERFAMILY SSF52317 3 220 1.22E-68 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 219 6.0E-78 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 PIRSF PIRSF001586 1 223 5.2E-77 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 219 37.95 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 Gene3D G3DSA:3.40.50.880 1 222 2.5E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS21905 ec24728c2889ab7e9308b7c2368393bc 224 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 205 2.7E-36 T 29-03-2018 MSG_RS19650 efead1ab1384500563f07f9c0a9781a4 355 Gene3D G3DSA:3.40.50.1820 81 354 2.1E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19650 efead1ab1384500563f07f9c0a9781a4 355 Pfam PF07859 alpha/beta hydrolase fold 124 330 7.4E-43 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS19650 efead1ab1384500563f07f9c0a9781a4 355 SUPERFAMILY SSF53474 70 352 2.06E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19650 efead1ab1384500563f07f9c0a9781a4 355 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 192 204 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site MSG_RS11920 8823eadaafe8fcb85e17cc09ff64271b 414 SUPERFAMILY SSF53756 4 410 1.5E-56 T 29-03-2018 MSG_RS11920 8823eadaafe8fcb85e17cc09ff64271b 414 Pfam PF13439 Glycosyltransferase Family 4 14 219 3.7E-23 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS11920 8823eadaafe8fcb85e17cc09ff64271b 414 Gene3D G3DSA:3.40.50.2000 1 227 4.6E-18 T 29-03-2018 MSG_RS11920 8823eadaafe8fcb85e17cc09ff64271b 414 Pfam PF00534 Glycosyl transferases group 1 235 382 1.1E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS11920 8823eadaafe8fcb85e17cc09ff64271b 414 Gene3D G3DSA:3.40.50.2000 228 384 8.9E-27 T 29-03-2018 MSG_RS22695 0df61bf60f7f97bb0af87073822c6a82 413 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 4.9E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MSG_RS22695 0df61bf60f7f97bb0af87073822c6a82 413 PRINTS PR00758 Arsenical pump membrane protein signature 347 372 4.9E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MSG_RS22695 0df61bf60f7f97bb0af87073822c6a82 413 PRINTS PR00758 Arsenical pump membrane protein signature 380 404 4.9E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MSG_RS22695 0df61bf60f7f97bb0af87073822c6a82 413 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 4.9E-15 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MSG_RS22695 0df61bf60f7f97bb0af87073822c6a82 413 Pfam PF02040 Arsenical pump membrane protein 5 404 4.9E-23 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MSG_RS03285 226e5922dfa910061235bf2074507adb 147 Pfam PF05423 Mycobacterium membrane protein 10 147 1.4E-56 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS02755 bf8c2c508f6c043dff2c79109dce4be1 391 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 101 318 4.0E-33 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS00240 61af8dc7fc3dd53fe83b1d741fc6bf5e 400 Pfam PF00823 PPE family 9 161 1.2E-17 T 29-03-2018 IPR000030 PPE family MSG_RS00240 61af8dc7fc3dd53fe83b1d741fc6bf5e 400 SUPERFAMILY SSF140459 9 171 1.46E-19 T 29-03-2018 MSG_RS10305 00daf9d48fb364cd8bd2e3eb14201bcf 244 Pfam PF07947 YhhN family 48 226 4.3E-45 T 29-03-2018 IPR012506 YhhN-like GO:0016021 MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 Pfam PF00106 short chain dehydrogenase 10 199 1.2E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 7.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 7.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 7.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 SUPERFAMILY SSF51735 5 267 1.08E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 Gene3D G3DSA:3.40.50.720 4 293 7.2E-51 T 29-03-2018 MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 200 0.0038 T 29-03-2018 MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 8.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 8.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 8.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 8.6E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14515 ec36f1612a428f070b6afe1a32514418 319 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS04940 57da73fbabd4abce42cfc65acac32545 279 SUPERFAMILY SSF53474 12 206 3.75E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04940 57da73fbabd4abce42cfc65acac32545 279 Gene3D G3DSA:3.40.50.1820 25 263 8.2E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17620 fb3f5a628212891b380e8fed0c32520f 337 SUPERFAMILY SSF54593 9 127 2.62E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS17620 fb3f5a628212891b380e8fed0c32520f 337 Gene3D G3DSA:3.10.180.10 140 299 2.8E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS17620 fb3f5a628212891b380e8fed0c32520f 337 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 149 273 3.0E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS17620 fb3f5a628212891b380e8fed0c32520f 337 Gene3D G3DSA:3.10.180.10 13 132 9.9E-7 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS17620 fb3f5a628212891b380e8fed0c32520f 337 SUPERFAMILY SSF54593 141 299 4.03E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 Gene3D G3DSA:3.40.1400.10 3 155 1.6E-55 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 6 150 2.8E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 PIRSF PIRSF005384 4 152 1.5E-50 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 4 151 5.1E-67 T 29-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 SUPERFAMILY SSF89623 4 155 1.83E-52 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MSG_RS17255 ff669dccc6f3005524a5dd74f57ec418 162 Pfam PF02502 Ribose/Galactose Isomerase 6 143 3.9E-45 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MSG_RS18410 b14abae3f6466290a08dc2caa0793701 91 Pfam PF05305 Protein of unknown function (DUF732) 6 90 2.2E-12 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS15690 cfdb19782be40190a9fe1a4055d3c552 181 Pfam PF05423 Mycobacterium membrane protein 35 181 1.3E-34 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS10135 7dd21a4b7ff4d63d2759f6deda4f27aa 192 SUPERFAMILY SSF52499 6 188 3.4E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS10135 7dd21a4b7ff4d63d2759f6deda4f27aa 192 Gene3D G3DSA:3.40.50.850 7 192 2.0E-44 T 29-03-2018 MSG_RS10135 7dd21a4b7ff4d63d2759f6deda4f27aa 192 Pfam PF00857 Isochorismatase family 13 183 1.8E-37 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS07165 0b4413f277c6e31d1d52259395c2ccb3 124 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 4 122 1.4E-30 T 29-03-2018 IPR013100 Limonene-1,2-epoxide hydrolase MSG_RS07165 0b4413f277c6e31d1d52259395c2ccb3 124 SUPERFAMILY SSF54427 1 123 2.51E-34 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS07165 0b4413f277c6e31d1d52259395c2ccb3 124 Gene3D G3DSA:3.10.450.50 1 124 8.5E-27 T 29-03-2018 MSG_RS06410 608c082938178d24768a5d5a3b60f602 123 Gene3D G3DSA:1.10.10.60 19 88 3.4E-5 T 29-03-2018 MSG_RS06410 608c082938178d24768a5d5a3b60f602 123 Pfam PF13556 PucR C-terminal helix-turn-helix domain 54 107 3.7E-16 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MSG_RS00295 651331e707a30190193c78341ac2a718 605 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 374 472 1.2E-18 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MSG_RS00295 651331e707a30190193c78341ac2a718 605 SUPERFAMILY SSF53850 92 315 1.34E-45 T 29-03-2018 MSG_RS00295 651331e707a30190193c78341ac2a718 605 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 95 310 6.6E-38 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS00295 651331e707a30190193c78341ac2a718 605 SMART SM00062 94 313 4.6E-37 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS00295 651331e707a30190193c78341ac2a718 605 SUPERFAMILY SSF161098 374 567 1.09E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS00295 651331e707a30190193c78341ac2a718 605 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 393 582 8.1E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS00295 651331e707a30190193c78341ac2a718 605 Gene3D G3DSA:3.40.190.10 89 237 3.9E-27 T 29-03-2018 MSG_RS00295 651331e707a30190193c78341ac2a718 605 Gene3D G3DSA:1.10.3720.10 238 585 1.7E-47 T 29-03-2018 MSG_RS18540 4498c0a741ed660023e0d1552fba36b5 182 Pfam PF12079 Protein of unknown function (DUF3558) 17 180 6.6E-39 T 29-03-2018 IPR024520 Protein of unknown function DUF3558 MSG_RS18540 4498c0a741ed660023e0d1552fba36b5 182 Gene3D G3DSA:3.40.190.10 2 174 2.5E-8 T 29-03-2018 MSG_RS18540 4498c0a741ed660023e0d1552fba36b5 182 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 22 182 3.0E-83 T 29-03-2018 MSG_RS14835 648440d6a492ba2e3bfb26a3da9ed99d 523 Pfam PF02470 MlaD protein 46 124 1.2E-6 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS14835 648440d6a492ba2e3bfb26a3da9ed99d 523 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 197 384 8.9E-14 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS11700 d45a814c1b2d21f9783b4dd504b2f068 306 Hamap MF_00361 NAD kinase [nadK]. 5 298 30.088 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MSG_RS11700 d45a814c1b2d21f9783b4dd504b2f068 306 SUPERFAMILY SSF111331 6 304 7.19E-80 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MSG_RS11700 d45a814c1b2d21f9783b4dd504b2f068 306 Gene3D G3DSA:2.60.200.30 153 275 8.2E-34 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MSG_RS11700 d45a814c1b2d21f9783b4dd504b2f068 306 Gene3D G3DSA:3.40.50.10330 1 152 2.8E-34 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MSG_RS11700 d45a814c1b2d21f9783b4dd504b2f068 306 Pfam PF01513 ATP-NAD kinase 6 282 8.5E-74 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 384 1.8E-121 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 Pfam PF00108 Thiolase, N-terminal domain 5 256 8.7E-57 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 SUPERFAMILY SSF53901 264 385 8.57E-40 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 Pfam PF02803 Thiolase, C-terminal domain 264 385 3.7E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 PIRSF PIRSF000429 1 386 2.6E-112 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 Gene3D G3DSA:3.40.47.10 1 266 4.2E-47 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 SUPERFAMILY SSF53901 3 263 1.5E-63 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22560 895f2a0478dc336c9a65378c36132679 386 Gene3D G3DSA:3.40.47.10 267 383 3.1E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20765 d204ae7ec3ab34b4210daf3190930889 552 Gene3D G3DSA:1.20.1250.20 103 325 1.2E-7 T 29-03-2018 MSG_RS20765 d204ae7ec3ab34b4210daf3190930889 552 Pfam PF07690 Major Facilitator Superfamily 122 485 2.3E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS20765 d204ae7ec3ab34b4210daf3190930889 552 SUPERFAMILY SSF103473 124 512 1.13E-15 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS20765 d204ae7ec3ab34b4210daf3190930889 552 Gene3D G3DSA:1.20.1250.20 342 519 3.6E-9 T 29-03-2018 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 Pfam PF00067 Cytochrome P450 193 368 1.2E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 SUPERFAMILY SSF48264 11 400 2.36E-84 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 Gene3D G3DSA:1.10.630.10 2 399 1.1E-59 T 29-03-2018 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 273 284 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 146 161 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 318 333 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 341 350 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 129 145 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 290 317 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 187 209 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 84 95 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS21250 ad7cddd5871f77efd0386df7c326497f 401 PRINTS PR00359 B-class P450 signature 350 361 1.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS01720 5a930e40603bc98b25eb28035c30c0a8 289 Pfam PF02405 Permease MlaE 70 271 9.5E-49 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS04995 1eed1ceebd186e4755c1a859785d3cd7 160 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 15 141 3.4E-20 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MSG_RS04995 1eed1ceebd186e4755c1a859785d3cd7 160 SUPERFAMILY SSF52540 23 136 4.32E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04995 1eed1ceebd186e4755c1a859785d3cd7 160 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 139 3.2E-29 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MSG_RS04995 1eed1ceebd186e4755c1a859785d3cd7 160 Gene3D G3DSA:3.40.50.300 4 160 2.8E-42 T 29-03-2018 MSG_RS02225 b2dc03403b80434c3865f524d0a5e992 153 Gene3D G3DSA:2.60.40.790 3 153 8.5E-29 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS02225 b2dc03403b80434c3865f524d0a5e992 153 SUPERFAMILY SSF49764 15 136 4.19E-27 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS02225 b2dc03403b80434c3865f524d0a5e992 153 Pfam PF00011 Hsp20/alpha crystallin family 44 151 2.1E-16 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MSG_RS16870 fd65e63226135527d96e7eb6c51fc092 270 Gene3D G3DSA:3.40.50.1400 152 267 1.2E-16 T 29-03-2018 MSG_RS16870 fd65e63226135527d96e7eb6c51fc092 270 Gene3D G3DSA:3.40.50.1400 33 151 2.3E-21 T 29-03-2018 MSG_RS16870 fd65e63226135527d96e7eb6c51fc092 270 Pfam PF01903 CbiX 42 139 8.7E-16 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MSG_RS16870 fd65e63226135527d96e7eb6c51fc092 270 Pfam PF01903 CbiX 186 256 1.1E-8 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MSG_RS16870 fd65e63226135527d96e7eb6c51fc092 270 SUPERFAMILY SSF53800 37 263 4.49E-29 T 29-03-2018 MSG_RS00470 f1dd59cd54723351e6a2955591354328 111 SUPERFAMILY SSF52091 13 97 4.32E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS00470 f1dd59cd54723351e6a2955591354328 111 Gene3D G3DSA:3.30.750.24 5 98 2.0E-9 T 29-03-2018 IPR002645 STAS domain MSG_RS00470 f1dd59cd54723351e6a2955591354328 111 Pfam PF13466 STAS domain 19 76 7.1E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 SUPERFAMILY SSF51735 6 274 7.82E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 5.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 5.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 5.9E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 272 3.6E-49 T 29-03-2018 MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 Gene3D G3DSA:3.40.50.720 5 274 9.2E-65 T 29-03-2018 MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 8 273 2.9E-103 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 6.0E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23645 2749b1c277da2351abdcfadea77a2550 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS16595 5330f0e166d2e4a4d14043d4d2b518fc 229 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 3 209 1.4E-51 T 29-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 MSG_RS16595 5330f0e166d2e4a4d14043d4d2b518fc 229 Gene3D G3DSA:3.40.50.1000 87 226 3.6E-14 T 29-03-2018 IPR023214 HAD-like domain MSG_RS16595 5330f0e166d2e4a4d14043d4d2b518fc 229 SUPERFAMILY SSF56784 3 223 1.19E-41 T 29-03-2018 IPR023214 HAD-like domain MSG_RS10660 152773b6103d987d9684547ed0858adb 303 Pfam PF01882 Protein of unknown function DUF58 42 123 3.7E-20 T 29-03-2018 IPR002881 Domain of unknown function DUF58 MSG_RS10660 152773b6103d987d9684547ed0858adb 303 SUPERFAMILY SSF53300 81 214 2.56E-5 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS10660 152773b6103d987d9684547ed0858adb 303 Gene3D G3DSA:3.40.50.410 54 262 6.2E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS03015 f59ce6d350a708eebb9305f99de329cc 226 SUPERFAMILY SSF51391 6 221 1.83E-56 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MSG_RS03015 f59ce6d350a708eebb9305f99de329cc 226 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 223 24.277 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MSG_RS03015 f59ce6d350a708eebb9305f99de329cc 226 Pfam PF02581 Thiamine monophosphate synthase 13 205 1.1E-49 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MSG_RS03015 f59ce6d350a708eebb9305f99de329cc 226 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 218 2.0E-60 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MSG_RS03015 f59ce6d350a708eebb9305f99de329cc 226 Gene3D G3DSA:3.20.20.70 2 223 2.6E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 SUPERFAMILY SSF50129 1 205 3.1E-55 T 29-03-2018 IPR011032 GroES-like MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 SUPERFAMILY SSF51735 171 346 6.36E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 SUPERFAMILY SSF50129 332 381 3.11E-8 T 29-03-2018 IPR011032 GroES-like MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 72 86 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 3 382 3.2E-147 T 29-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 Gene3D G3DSA:3.90.180.10 1 209 1.4E-50 T 29-03-2018 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 Pfam PF00107 Zinc-binding dehydrogenase 209 335 1.2E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 167 4.1E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MSG_RS17815 f795e8d88f8a13dbc01d21abba011a0c 385 Gene3D G3DSA:3.40.50.720 210 329 1.9E-12 T 29-03-2018 MSG_RS06600 5cd24c784c3d863d8c49d56faa40b845 172 Gene3D G3DSA:3.30.750.24 25 140 1.3E-8 T 29-03-2018 IPR002645 STAS domain MSG_RS06600 5cd24c784c3d863d8c49d56faa40b845 172 SUPERFAMILY SSF52091 29 134 4.32E-11 T 29-03-2018 IPR002645 STAS domain MSG_RS06600 5cd24c784c3d863d8c49d56faa40b845 172 Pfam PF01740 STAS domain 33 104 3.9E-6 T 29-03-2018 IPR002645 STAS domain MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 257 279 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 349 365 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 397 411 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 630 642 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 646 662 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 507 516 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 411 431 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR01159 DNA gyrase subunit B signature 12 22 1.1E-73 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 SUPERFAMILY SSF56719 431 672 3.66E-81 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 561 573 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 541 558 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 76 89 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 120 134 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 609 625 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 457 471 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 41 56 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 305 318 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 PRINTS PR00418 DNA topoisomerase II family signature 523 539 1.5E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 608 665 3.2E-25 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 SUPERFAMILY SSF54211 258 428 2.85E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS00025 880d3164988d85cc297020361c1c64db 677 SMART SM00433 41 670 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 677 9.4E-297 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 SMART SM00387 37 181 8.8E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Gene3D G3DSA:3.40.50.670 439 674 2.7E-95 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Pfam PF00204 DNA gyrase B 258 427 4.1E-63 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 ProSitePatterns PS00177 DNA topoisomerase II signature. 459 467 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Gene3D G3DSA:3.30.230.10 262 429 3.6E-65 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS00025 880d3164988d85cc297020361c1c64db 677 SUPERFAMILY SSF55874 12 217 1.78E-64 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 677 95.104 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Gene3D G3DSA:3.30.565.10 22 261 2.0E-71 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 179 6.8E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS00025 880d3164988d85cc297020361c1c64db 677 Pfam PF01751 Toprim domain 456 566 2.5E-16 T 29-03-2018 IPR006171 TOPRIM domain MSG_RS14545 13b2f590c6069230e006ad9e451c9070 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 22.665 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 MSG_RS14545 13b2f590c6069230e006ad9e451c9070 111 Pfam PF13397 RNA polymerase-binding protein 4 106 7.8E-40 T 29-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 MSG_RS18530 63e52e2883b9585e55241c869ffb1b3a 158 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 72 8.6E-7 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS18530 63e52e2883b9585e55241c869ffb1b3a 158 Gene3D G3DSA:3.40.50.1240 1 158 5.8E-28 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS18530 63e52e2883b9585e55241c869ffb1b3a 158 SMART SM00855 1 105 0.001 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS18530 63e52e2883b9585e55241c869ffb1b3a 158 SUPERFAMILY SSF53254 1 141 9.42E-20 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS05250 3179851752499c3e8feba0aca775f62f 149 Pfam PF02417 Chromate transporter 16 82 4.3E-12 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 Gene3D G3DSA:2.20.28.10 16 57 1.6E-24 T 29-03-2018 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 ProSitePatterns PS00202 Rubredoxin signature. 36 46 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 Gene3D G3DSA:2.20.25.10 2 15 0.14 T 29-03-2018 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 PRINTS PR00163 Rubredoxin signature 36 52 3.6E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 PRINTS PR00163 Rubredoxin signature 6 22 3.6E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 Pfam PF00301 Rubredoxin 7 52 3.1E-22 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 SUPERFAMILY SSF57802 3 57 2.52E-22 T 29-03-2018 MSG_RS05885 f4aaed6a424b0e70a37c56877271cbc4 60 PIRSF PIRSF000071 3 60 1.4E-22 T 29-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 MSG_RS03535 836405e91522ffbb3e73a0e48c23813c 371 SUPERFAMILY SSF51735 16 332 2.98E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03535 836405e91522ffbb3e73a0e48c23813c 371 Pfam PF01370 NAD dependent epimerase/dehydratase family 21 205 2.5E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS03535 836405e91522ffbb3e73a0e48c23813c 371 Gene3D G3DSA:3.40.50.720 16 335 1.5E-38 T 29-03-2018 MSG_RS22955 a2912d6fbad6c6e4ebcdc3e1441ee831 322 Gene3D G3DSA:3.40.50.720 8 197 1.9E-36 T 29-03-2018 MSG_RS22955 a2912d6fbad6c6e4ebcdc3e1441ee831 322 SUPERFAMILY SSF51735 9 318 6.54E-88 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22955 a2912d6fbad6c6e4ebcdc3e1441ee831 322 Gene3D G3DSA:3.90.25.10 198 321 7.1E-36 T 29-03-2018 MSG_RS22955 a2912d6fbad6c6e4ebcdc3e1441ee831 322 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS22955 a2912d6fbad6c6e4ebcdc3e1441ee831 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 312 6.6E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18750 9fd2347a1b1bc32a1f53d738229d55ce 271 SUPERFAMILY SSF161098 33 253 1.96E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18750 9fd2347a1b1bc32a1f53d738229d55ce 271 Gene3D G3DSA:1.10.3720.10 1 261 4.3E-42 T 29-03-2018 MSG_RS18750 9fd2347a1b1bc32a1f53d738229d55ce 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 254 5.3E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS14275 8c1b70e4d6c801e4f006fc32f2429e47 388 Pfam PF02470 MlaD protein 49 122 2.2E-13 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS14275 8c1b70e4d6c801e4f006fc32f2429e47 388 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 303 8.1E-84 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 205 9.9E-46 T 29-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 Gene3D G3DSA:3.40.50.1000 89 235 2.3E-18 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 SUPERFAMILY SSF56784 7 236 3.54E-37 T 29-03-2018 IPR023214 HAD-like domain MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 10 191 5.2E-19 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 190 203 4.8E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 4.8E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 4.8E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 4.8E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS15855 57f479cf418d3b0489caf5604385ee13 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 102 201 1.8E-7 T 29-03-2018 IPR023214 HAD-like domain MSG_RS11400 c1793ca24b48209fb32e78e77dc16993 125 SUPERFAMILY SSF55021 3 60 1.46E-5 T 29-03-2018 MSG_RS11400 c1793ca24b48209fb32e78e77dc16993 125 Pfam PF13840 ACT domain 66 121 1.2E-9 T 29-03-2018 IPR027795 GATS-like ACT domain MSG_RS11400 c1793ca24b48209fb32e78e77dc16993 125 Gene3D G3DSA:3.30.2130.10 1 125 8.8E-16 T 29-03-2018 MSG_RS11400 c1793ca24b48209fb32e78e77dc16993 125 SUPERFAMILY SSF55021 65 123 4.35E-16 T 29-03-2018 MSG_RS11400 c1793ca24b48209fb32e78e77dc16993 125 Pfam PF10000 ACT domain 4 64 1.6E-10 T 29-03-2018 IPR018717 Domain of unknown function DUF2241 MSG_RS20370 9aadf1af6995ad6fb46ad85b4322d5b3 105 SMART SM00830 33 95 6.8E-8 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS20370 9aadf1af6995ad6fb46ad85b4322d5b3 105 SUPERFAMILY SSF48600 20 87 3.36E-14 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS20370 9aadf1af6995ad6fb46ad85b4322d5b3 105 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 29 101 3.2E-38 T 29-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal MSG_RS20370 9aadf1af6995ad6fb46ad85b4322d5b3 105 Pfam PF01817 Chorismate mutase type II 33 86 1.4E-10 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS20370 9aadf1af6995ad6fb46ad85b4322d5b3 105 Gene3D G3DSA:1.20.59.10 16 105 6.9E-18 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MSG_RS02880 38d4d25f83596db78a3e72d2d44eaaa3 138 Gene3D G3DSA:3.40.250.10 1 138 2.3E-19 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS02880 38d4d25f83596db78a3e72d2d44eaaa3 138 SUPERFAMILY SSF52821 4 137 1.83E-18 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS02880 38d4d25f83596db78a3e72d2d44eaaa3 138 SMART SM00450 8 122 1.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS02880 38d4d25f83596db78a3e72d2d44eaaa3 138 Pfam PF00581 Rhodanese-like domain 9 113 1.3E-6 T 29-03-2018 IPR001763 Rhodanese-like domain MSG_RS00860 c68167d299ea1fd466428ff8b8fa45eb 215 SUPERFAMILY SSF46785 13 190 1.43E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00860 c68167d299ea1fd466428ff8b8fa45eb 215 Pfam PF10400 Virulence activator alpha C-term 106 173 1.2E-4 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal MSG_RS00860 c68167d299ea1fd466428ff8b8fa45eb 215 Gene3D G3DSA:1.10.10.10 2 148 7.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03765 9119dfa27618de6678323e79eb0a994e 410 Pfam PF13520 Amino acid permease 12 366 1.3E-43 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS03765 9119dfa27618de6678323e79eb0a994e 410 PIRSF PIRSF006060 1 406 6.7E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS24065 b1e0792daaaeb685c4e2378bed7831bb 79 Gene3D G3DSA:2.40.50.140 1 70 2.3E-12 T 29-03-2018 MSG_RS24065 b1e0792daaaeb685c4e2378bed7831bb 79 SUPERFAMILY SSF141322 23 63 4.32E-6 T 29-03-2018 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 SUPERFAMILY SSF142338 3 326 3.92E-79 T 29-03-2018 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 330 135.898 T 29-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 Gene3D G3DSA:3.40.50.10680 101 329 3.0E-39 T 29-03-2018 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 Gene3D G3DSA:3.40.50.10680 3 93 9.1E-16 T 29-03-2018 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 Pfam PF01933 Uncharacterised protein family UPF0052 3 293 3.4E-63 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 MSG_RS05830 07312e1762e9513cd3d396e02f60d00b 330 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 323 9.6E-128 T 29-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 MSG_RS20595 b903889d35acd4cc3b4ab67df31d16b7 504 Pfam PF03055 Retinal pigment epithelial membrane protein 27 485 3.2E-95 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 MSG_RS12880 ead8ec305bfd22871046e0ccbb67231b 329 Gene3D G3DSA:1.10.620.20 3 329 6.9E-88 T 29-03-2018 MSG_RS12880 ead8ec305bfd22871046e0ccbb67231b 329 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 54 276 1.5E-60 T 29-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 MSG_RS12880 ead8ec305bfd22871046e0ccbb67231b 329 PIRSF PIRSF000040 2 329 4.4E-84 T 29-03-2018 IPR012078 Methane/phenol monooxygenase, hydroxylase component GO:0016709|GO:0055114 MSG_RS12880 ead8ec305bfd22871046e0ccbb67231b 329 SUPERFAMILY SSF47240 2 328 3.51E-79 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS08915 c31856ab3ce06999fe9f3d49d8fac6bc 229 SUPERFAMILY SSF53213 73 222 1.96E-5 T 29-03-2018 MSG_RS08915 c31856ab3ce06999fe9f3d49d8fac6bc 229 Gene3D G3DSA:3.40.830.10 1 109 0.0013 T 29-03-2018 MSG_RS08915 c31856ab3ce06999fe9f3d49d8fac6bc 229 Gene3D G3DSA:3.40.830.10 110 229 2.3E-14 T 29-03-2018 MSG_RS15510 ceee148c2b4d72ef8af9c154b2a5d293 520 SUPERFAMILY SSF53474 200 254 1.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15510 ceee148c2b4d72ef8af9c154b2a5d293 520 SUPERFAMILY SSF53474 98 154 1.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15510 ceee148c2b4d72ef8af9c154b2a5d293 520 SUPERFAMILY SSF53474 361 508 1.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15510 ceee148c2b4d72ef8af9c154b2a5d293 520 Pfam PF00561 alpha/beta hydrolase fold 102 497 6.7E-83 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS15510 ceee148c2b4d72ef8af9c154b2a5d293 520 Gene3D G3DSA:3.40.50.1820 85 511 4.5E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19735 e47491102e9459aed58c20fb12e4d749 251 SUPERFAMILY SSF53474 11 249 4.93E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19735 e47491102e9459aed58c20fb12e4d749 251 Pfam PF01738 Dienelactone hydrolase family 24 246 5.9E-39 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 MSG_RS19735 e47491102e9459aed58c20fb12e4d749 251 Gene3D G3DSA:3.40.50.1820 6 248 5.4E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10295 8dd52f2a77775721c943d3a034ca1fce 321 Gene3D G3DSA:3.40.50.1820 9 321 2.3E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10295 8dd52f2a77775721c943d3a034ca1fce 321 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 156 168 - T 29-03-2018 IPR033140 Lipase, GDXG, putative serine active site MSG_RS10295 8dd52f2a77775721c943d3a034ca1fce 321 Pfam PF07859 alpha/beta hydrolase fold 84 295 1.7E-70 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS10295 8dd52f2a77775721c943d3a034ca1fce 321 SUPERFAMILY SSF53474 55 319 5.07E-74 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00440 f77b0bc0e9f1079b531e7974a4f35369 148 SUPERFAMILY SSF53098 31 136 1.38E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS00440 f77b0bc0e9f1079b531e7974a4f35369 148 Pfam PF00665 Integrase core domain 42 135 3.9E-21 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MSG_RS00440 f77b0bc0e9f1079b531e7974a4f35369 148 Gene3D G3DSA:3.30.420.10 26 138 2.9E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS14070 84375f1bd54aaeefd0e3462350fbb290 228 Gene3D G3DSA:3.30.530.20 50 213 4.7E-14 T 29-03-2018 IPR023393 START-like domain MSG_RS14070 84375f1bd54aaeefd0e3462350fbb290 228 SUPERFAMILY SSF55961 56 208 1.52E-7 T 29-03-2018 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 SUPERFAMILY SSF55103 191 453 8.34E-56 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 452 8.8E-63 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 Pfam PF01565 FAD binding domain 41 178 3.6E-41 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 SUPERFAMILY SSF56176 4 214 3.83E-71 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 Gene3D G3DSA:3.30.465.10 94 238 3.4E-41 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 Gene3D G3DSA:3.30.43.10 1 93 2.8E-25 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS18620 7c2854d367cb1db3abcba8184de52723 455 Gene3D G3DSA:1.10.45.10 415 453 2.0E-14 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MSG_RS09695 e339aa310c1bc228d67cc21f59304da7 108 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 7.6E-26 T 29-03-2018 IPR003849 Preprotein translocase YajC MSG_RS09695 e339aa310c1bc228d67cc21f59304da7 108 SMART SM01323 2 84 1.3E-25 T 29-03-2018 IPR003849 Preprotein translocase YajC MSG_RS09695 e339aa310c1bc228d67cc21f59304da7 108 Pfam PF02699 Preprotein translocase subunit 6 81 2.7E-16 T 29-03-2018 IPR003849 Preprotein translocase YajC MSG_RS23715 268b3ed5a261d2e42ea938ec9c051559 145 Gene3D G3DSA:3.10.180.10 4 136 3.3E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23715 268b3ed5a261d2e42ea938ec9c051559 145 SUPERFAMILY SSF54593 5 120 6.04E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23715 268b3ed5a261d2e42ea938ec9c051559 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 95 3.6E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS23115 c0b2eff721ff8a0d0a49450147e43287 268 SUPERFAMILY SSF55811 91 233 2.84E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS23115 c0b2eff721ff8a0d0a49450147e43287 268 Gene3D G3DSA:3.90.79.10 45 241 7.8E-31 T 29-03-2018 MSG_RS23115 c0b2eff721ff8a0d0a49450147e43287 268 Pfam PF00293 NUDIX domain 95 185 2.4E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS23115 c0b2eff721ff8a0d0a49450147e43287 268 ProSitePatterns PS01293 Nudix CoA signature. 97 117 - T 29-03-2018 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 Gene3D G3DSA:3.30.460.20 27 172 7.3E-33 T 29-03-2018 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 SUPERFAMILY SSF144083 299 361 7.98E-18 T 29-03-2018 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 Gene3D G3DSA:1.20.58.340 181 296 6.4E-30 T 29-03-2018 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 Gene3D G3DSA:1.20.58.340 297 364 1.1E-16 T 29-03-2018 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 SUPERFAMILY SSF143865 25 296 2.62E-62 T 29-03-2018 MSG_RS18730 be5ec8ea2f1f4a9a3b93cb24edeadeca 364 Pfam PF01544 CorA-like Mg2+ transporter protein 66 360 3.3E-60 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 SUPERFAMILY SSF47203 228 382 1.53E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 209 2.6E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Gene3D G3DSA:1.20.140.10 226 387 4.5E-26 T 29-03-2018 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.5E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Gene3D G3DSA:2.40.110.10 122 225 6.5E-33 T 29-03-2018 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 SUPERFAMILY SSF56645 4 241 1.1E-69 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 378 9.9E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS22490 549ca2e63950a5a49019da1bd12a344c 387 Gene3D G3DSA:1.10.540.10 1 120 1.0E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02985 d75bbfedb1ccaaec427287e7b5724b9d 438 Pfam PF08811 Protein of unknown function (DUF1800) 14 436 2.8E-87 T 29-03-2018 IPR014917 Protein of unknown function DUF1800 MSG_RS06850 2059ec976d1ea1d105a99863e34b2183 142 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 11 127 9.0E-27 T 29-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MSG_RS06850 2059ec976d1ea1d105a99863e34b2183 142 SUPERFAMILY SSF50475 7 130 1.57E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS06850 2059ec976d1ea1d105a99863e34b2183 142 Gene3D G3DSA:2.30.110.10 1 136 2.5E-14 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS14485 84dfeb75d0cc5dbcaead2e91788401d3 317 Pfam PF07681 DoxX 6 95 3.3E-11 T 29-03-2018 IPR032808 DoxX family MSG_RS14485 84dfeb75d0cc5dbcaead2e91788401d3 317 Gene3D G3DSA:1.20.120.20 27 310 7.9E-4 T 29-03-2018 MSG_RS20505 1e882cb651f4108706c42e73651ef718 353 Gene3D G3DSA:3.10.490.10 1 158 1.3E-40 T 29-03-2018 MSG_RS20505 1e882cb651f4108706c42e73651ef718 353 Pfam PF05908 Poly-gamma-glutamate hydrolase 161 322 4.5E-38 T 29-03-2018 IPR008585 Poly-gamma-glutamate hydrolase MSG_RS20505 1e882cb651f4108706c42e73651ef718 353 Pfam PF13772 AIG2-like family 57 137 1.2E-13 T 29-03-2018 MSG_RS20505 1e882cb651f4108706c42e73651ef718 353 SUPERFAMILY SSF110857 4 134 9.42E-23 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like MSG_RS22965 cfa4ce63f692eb9aee9623be1002847c 262 SUPERFAMILY SSF53448 9 236 7.69E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS22965 cfa4ce63f692eb9aee9623be1002847c 262 Gene3D G3DSA:3.90.550.10 11 241 7.2E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS22965 cfa4ce63f692eb9aee9623be1002847c 262 Pfam PF00535 Glycosyl transferase family 2 13 133 1.1E-14 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS05040 1bb5353020f9fa6d7541559286275dba 123 Gene3D G3DSA:3.40.50.10600 2 119 2.4E-8 T 29-03-2018 MSG_RS05040 1bb5353020f9fa6d7541559286275dba 123 SUPERFAMILY SSF52091 1 118 4.71E-25 T 29-03-2018 IPR002645 STAS domain MSG_RS05040 1bb5353020f9fa6d7541559286275dba 123 Pfam PF11964 SpoIIAA-like 12 118 1.1E-9 T 29-03-2018 IPR021866 SpoIIAA-like MSG_RS10495 ac33b169a8d9ccb40a95adf730ac237f 249 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 7 245 6.5E-78 T 29-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 MSG_RS10495 ac33b169a8d9ccb40a95adf730ac237f 249 SUPERFAMILY SSF100950 6 246 1.02E-66 T 29-03-2018 MSG_RS10495 ac33b169a8d9ccb40a95adf730ac237f 249 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 235 3.3E-74 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MSG_RS10495 ac33b169a8d9ccb40a95adf730ac237f 249 Gene3D G3DSA:3.40.50.1360 4 249 5.1E-78 T 29-03-2018 MSG_RS19200 ca3c10be182de86ff31816566c223334 238 SUPERFAMILY SSF52467 2 233 2.8E-78 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS19200 ca3c10be182de86ff31816566c223334 238 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 1 235 59.637 T 29-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 MSG_RS19200 ca3c10be182de86ff31816566c223334 238 Gene3D G3DSA:3.40.50.1220 1 237 3.0E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MSG_RS19200 ca3c10be182de86ff31816566c223334 238 Pfam PF02146 Sir2 family 8 185 8.7E-53 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 MSG_RS13855 33d46265a5a488823e9453774721736f 295 Gene3D G3DSA:3.40.50.620 2 154 2.3E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13855 33d46265a5a488823e9453774721736f 295 SUPERFAMILY SSF52402 10 153 1.17E-30 T 29-03-2018 MSG_RS13855 33d46265a5a488823e9453774721736f 295 Pfam PF00582 Universal stress protein family 162 293 1.2E-26 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13855 33d46265a5a488823e9453774721736f 295 Pfam PF00582 Universal stress protein family 10 148 3.4E-27 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS13855 33d46265a5a488823e9453774721736f 295 PRINTS PR01438 Universal stress protein signature 253 265 5.5E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13855 33d46265a5a488823e9453774721736f 295 PRINTS PR01438 Universal stress protein signature 271 293 5.5E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13855 33d46265a5a488823e9453774721736f 295 PRINTS PR01438 Universal stress protein signature 159 177 5.5E-17 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS13855 33d46265a5a488823e9453774721736f 295 Gene3D G3DSA:3.40.50.620 155 295 4.1E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS13855 33d46265a5a488823e9453774721736f 295 SUPERFAMILY SSF52402 161 293 1.0E-31 T 29-03-2018 MSG_RS19125 b9ea11835cd6bee8c9fd8b611b19680f 310 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 29 283 2.8E-67 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS19125 b9ea11835cd6bee8c9fd8b611b19680f 310 SUPERFAMILY SSF51679 16 304 2.75E-59 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS19125 b9ea11835cd6bee8c9fd8b611b19680f 310 Pfam PF00296 Luciferase-like monooxygenase 17 261 8.5E-49 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS19125 b9ea11835cd6bee8c9fd8b611b19680f 310 Gene3D G3DSA:3.20.20.30 3 309 1.9E-63 T 29-03-2018 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 SUPERFAMILY SSF46785 1 49 1.32E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Pfam PF13404 AsnC-type helix-turn-helix domain 177 214 2.2E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 2.0E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Gene3D G3DSA:1.10.10.10 178 221 3.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Gene3D G3DSA:3.30.70.920 51 138 1.8E-5 T 29-03-2018 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Gene3D G3DSA:1.10.10.10 1 50 1.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 SMART SM00344 177 278 1.2E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 SMART SM00344 1 105 4.5E-5 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Pfam PF01037 Lrp/AsnC ligand binding domain 238 305 1.5E-9 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 SUPERFAMILY SSF54909 232 311 3.08E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS10280 d20209e83c78fd0e43fd9a3cef37ce4f 326 Gene3D G3DSA:3.30.70.920 225 316 1.1E-16 T 29-03-2018 MSG_RS10350 32e5368f1cac6aa232f56048125a389e 234 SUPERFAMILY SSF89392 34 229 4.19E-59 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MSG_RS10350 32e5368f1cac6aa232f56048125a389e 234 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 16 228 1.0E-100 T 29-03-2018 IPR009830 LppX/LprAFG lipoprotein family MSG_RS10350 32e5368f1cac6aa232f56048125a389e 234 Pfam PF07161 LppX_LprAFG lipoprotein 37 228 9.3E-76 T 29-03-2018 IPR009830 LppX/LprAFG lipoprotein family MSG_RS10350 32e5368f1cac6aa232f56048125a389e 234 Gene3D G3DSA:3.40.190.10 1 229 2.3E-6 T 29-03-2018 MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 11 299 52.921 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 Gene3D G3DSA:3.90.226.10 3 239 2.1E-70 T 29-03-2018 MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 Gene3D G3DSA:1.10.12.10 240 288 9.0E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 SUPERFAMILY SSF52096 22 296 2.73E-77 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 294 9.5E-52 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS03805 8c21086e47d2d76999aeca50a96123c0 300 TIGRFAM TIGR01929 menB: naphthoate synthase 20 296 6.7E-137 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MSG_RS05815 39845f76fe1fcd6f3bd63fa595c8ffbd 183 Gene3D G3DSA:3.90.79.10 14 178 9.7E-21 T 29-03-2018 MSG_RS05815 39845f76fe1fcd6f3bd63fa595c8ffbd 183 SUPERFAMILY SSF55811 32 163 7.72E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS05815 39845f76fe1fcd6f3bd63fa595c8ffbd 183 Pfam PF00293 NUDIX domain 47 161 2.0E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 SUPERFAMILY SSF103473 474 503 1.96E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 SUPERFAMILY SSF103473 6 198 1.96E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 SUPERFAMILY SSF103473 254 437 1.96E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 Gene3D G3DSA:1.20.1250.20 266 511 4.1E-15 T 29-03-2018 MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 83 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 Gene3D G3DSA:1.20.1250.20 3 202 1.2E-29 T 29-03-2018 MSG_RS10345 1546d2a7dfa743b6cf94c876a76a1b67 521 Pfam PF07690 Major Facilitator Superfamily 16 428 8.0E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS24555 36f86d88ba43a47fc2d4e2a0c97aeeb1 582 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 242 354 4.2E-11 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MSG_RS24555 36f86d88ba43a47fc2d4e2a0c97aeeb1 582 SUPERFAMILY SSF53756 70 384 1.13E-34 T 29-03-2018 MSG_RS24555 36f86d88ba43a47fc2d4e2a0c97aeeb1 582 Gene3D G3DSA:3.40.50.2000 232 389 3.3E-24 T 29-03-2018 MSG_RS24555 36f86d88ba43a47fc2d4e2a0c97aeeb1 582 Pfam PF14063 Protein of unknown function (DUF4254) 436 560 1.5E-32 T 29-03-2018 IPR025350 Protein of unknown function DUF4254 MSG_RS13475 517db353d928f68e017ca44738013a39 394 SUPERFAMILY SSF47203 232 388 1.19E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS13475 517db353d928f68e017ca44738013a39 394 Gene3D G3DSA:1.10.540.10 3 102 4.8E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS13475 517db353d928f68e017ca44738013a39 394 PIRSF PIRSF016578 1 394 1.7E-107 T 29-03-2018 MSG_RS13475 517db353d928f68e017ca44738013a39 394 Gene3D G3DSA:1.20.140.10 220 381 1.4E-18 T 29-03-2018 MSG_RS13475 517db353d928f68e017ca44738013a39 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 373 9.0E-34 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MSG_RS13475 517db353d928f68e017ca44738013a39 394 SUPERFAMILY SSF56645 15 215 4.93E-20 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS13475 517db353d928f68e017ca44738013a39 394 Gene3D G3DSA:2.40.110.10 123 217 1.5E-10 T 29-03-2018 MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 SUPERFAMILY SSF51735 13 268 6.94E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 8.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 8.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 8.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 265 1.0E-41 T 29-03-2018 MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 Gene3D G3DSA:3.40.50.720 2 270 6.3E-52 T 29-03-2018 MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 3.8E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12465 4053fde1bf7ad816a7d299923c8dbf55 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Gene3D G3DSA:1.10.150.130 6 121 1.9E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 100 6.8E-25 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 8 312 55.518 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 12 312 5.7E-103 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Pfam PF00589 Phage integrase family 122 296 2.8E-47 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 6 312 59.097 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 SUPERFAMILY SSF56349 11 304 8.54E-54 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MSG_RS11730 bc19a9bc25dd37b5bb303444e2f7d574 313 Gene3D G3DSA:1.10.443.10 122 306 8.4E-50 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 Gene3D G3DSA:3.40.50.720 2 253 4.1E-66 T 29-03-2018 MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 9.4E-56 T 29-03-2018 MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 SUPERFAMILY SSF51735 5 251 6.75E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07170 c6be5347bd8a29751ff4bb83ef7d2bf5 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.1E-4 T 29-03-2018 MSG_RS01640 ffab702cb64c6b339573934f594f1462 92 SUPERFAMILY SSF51395 8 58 2.6E-6 T 29-03-2018 MSG_RS01640 ffab702cb64c6b339573934f594f1462 92 Gene3D G3DSA:3.20.20.70 5 75 1.7E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS02805 94d12a4630b5ad264d95796c35802d66 216 Pfam PF00588 SpoU rRNA Methylase family 67 203 1.8E-24 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MSG_RS02805 94d12a4630b5ad264d95796c35802d66 216 Gene3D G3DSA:3.40.1280.10 50 215 1.5E-48 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS02805 94d12a4630b5ad264d95796c35802d66 216 SUPERFAMILY SSF75217 51 211 1.11E-37 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS13575 3f35312f59f22877f4a710542115023f 215 ProSitePatterns PS00155 Cutinase, serine active site. 98 110 - T 29-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 MSG_RS13575 3f35312f59f22877f4a710542115023f 215 Pfam PF01083 Cutinase 30 214 2.7E-49 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS13575 3f35312f59f22877f4a710542115023f 215 SMART SM01110 28 214 1.2E-84 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS13575 3f35312f59f22877f4a710542115023f 215 Gene3D G3DSA:3.40.50.1820 16 215 4.5E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13575 3f35312f59f22877f4a710542115023f 215 SUPERFAMILY SSF53474 29 214 6.86E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04585 1d723f7630bf7ca9a4f9d9f6cc271fbf 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 8 122 4.9E-46 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04585 1d723f7630bf7ca9a4f9d9f6cc271fbf 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 8 122 26.522 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04585 1d723f7630bf7ca9a4f9d9f6cc271fbf 122 Gene3D G3DSA:3.30.420.100 3 122 2.8E-38 T 29-03-2018 MSG_RS04585 1d723f7630bf7ca9a4f9d9f6cc271fbf 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 11 122 1.8E-36 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04585 1d723f7630bf7ca9a4f9d9f6cc271fbf 122 SUPERFAMILY SSF53137 9 120 2.16E-46 T 29-03-2018 MSG_RS07985 5beaf7e1e8f437e4bcf2b830832f6852 488 Gene3D G3DSA:3.20.20.70 29 471 1.2E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS07985 5beaf7e1e8f437e4bcf2b830832f6852 488 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 23 463 9.9E-182 T 29-03-2018 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MSG_RS07985 5beaf7e1e8f437e4bcf2b830832f6852 488 SUPERFAMILY SSF51412 35 321 1.01E-21 T 29-03-2018 MSG_RS07985 5beaf7e1e8f437e4bcf2b830832f6852 488 Pfam PF03060 Nitronate monooxygenase 39 311 6.6E-9 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS19465 a4968651dadd6c83c08901b6d85cb753 112 Pfam PF05305 Protein of unknown function (DUF732) 15 107 3.5E-16 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS15775 b7998b3bef9e41aa8633f65ae48ec329 309 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 13 306 1.5E-39 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase MSG_RS15775 b7998b3bef9e41aa8633f65ae48ec329 309 SMART SM00046 12 144 0.001 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS15775 b7998b3bef9e41aa8633f65ae48ec329 309 SUPERFAMILY SSF111331 12 307 3.05E-68 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MSG_RS15775 b7998b3bef9e41aa8633f65ae48ec329 309 Gene3D G3DSA:3.40.50.10330 5 146 2.1E-27 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MSG_RS15775 b7998b3bef9e41aa8633f65ae48ec329 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 13 135 3.6E-27 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS10400 8330b0adcf161d117efba53b50ec75fc 325 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 2.7E-22 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain MSG_RS10400 8330b0adcf161d117efba53b50ec75fc 325 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 2 302 2.3E-108 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like MSG_RS10400 8330b0adcf161d117efba53b50ec75fc 325 Pfam PF02650 WhiA C-terminal HTH domain 219 301 4.9E-20 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal MSG_RS10400 8330b0adcf161d117efba53b50ec75fc 325 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 1 304 28.89 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 MSG_RS10400 8330b0adcf161d117efba53b50ec75fc 325 Pfam PF14527 WhiA LAGLIDADG-like domain 125 216 1.7E-24 T 29-03-2018 MSG_RS10115 0df4a9906560aefd4adfc90d337d033c 464 Pfam PF00171 Aldehyde dehydrogenase family 2 457 3.1E-168 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS10115 0df4a9906560aefd4adfc90d337d033c 464 Gene3D G3DSA:3.40.309.10 250 443 2.7E-67 T 29-03-2018 MSG_RS10115 0df4a9906560aefd4adfc90d337d033c 464 SUPERFAMILY SSF53720 2 460 1.31E-157 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS10115 0df4a9906560aefd4adfc90d337d033c 464 Gene3D G3DSA:3.40.605.10 1 249 6.2E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS10115 0df4a9906560aefd4adfc90d337d033c 464 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 SUPERFAMILY SSF53720 21 453 2.23E-123 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 Gene3D G3DSA:3.40.605.10 2 246 1.9E-72 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 Pfam PF00171 Aldehyde dehydrogenase family 12 444 4.6E-92 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 PIRSF PIRSF036492 3 473 1.7E-172 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 255 266 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 227 234 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS01520 9f597c9a7d58d862332d0b0111b98ea8 473 Gene3D G3DSA:3.40.309.10 247 424 3.7E-62 T 29-03-2018 MSG_RS02080 6c8ff21da7638ade7356a2ca2604d0c7 326 Pfam PF02126 Phosphotriesterase family 11 320 7.5E-133 T 29-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 MSG_RS02080 6c8ff21da7638ade7356a2ca2604d0c7 326 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 29-03-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 MSG_RS02080 6c8ff21da7638ade7356a2ca2604d0c7 326 SUPERFAMILY SSF51556 4 320 2.34E-85 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS02080 6c8ff21da7638ade7356a2ca2604d0c7 326 Gene3D G3DSA:3.20.20.140 1 320 2.9E-58 T 29-03-2018 MSG_RS00430 39e6f5610df693aed0ae3bfd72003c5d 138 Pfam PF00296 Luciferase-like monooxygenase 12 132 4.7E-10 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00430 39e6f5610df693aed0ae3bfd72003c5d 138 SUPERFAMILY SSF51679 1 133 2.69E-13 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00430 39e6f5610df693aed0ae3bfd72003c5d 138 Gene3D G3DSA:3.20.20.30 1 136 2.9E-14 T 29-03-2018 MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 7 360 2.9E-95 T 29-03-2018 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 24 69 9.2E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 SUPERFAMILY SSF55124 175 293 1.09E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 SUPERFAMILY SSF55124 4 84 7.52E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 Gene3D G3DSA:3.30.413.10 298 369 4.1E-4 T 29-03-2018 MSG_RS14605 d0365a8ce38223da8b71f5d5596df340 370 Gene3D G3DSA:3.90.480.10 24 296 2.7E-39 T 29-03-2018 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 Hamap MF_00568 Quinolinate synthase A [nadA]. 32 342 42.039 T 29-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 Pfam PF02445 Quinolinate synthetase A protein 37 341 5.1E-107 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 36 342 2.5E-86 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 Gene3D G3DSA:3.40.50.10800 209 324 5.2E-28 T 29-03-2018 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 Gene3D G3DSA:3.40.50.10800 30 111 1.3E-19 T 29-03-2018 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 Gene3D G3DSA:3.40.50.10800 116 208 2.1E-25 T 29-03-2018 MSG_RS11130 00bf42b803dc263924cebc9ac0fd44a5 349 SUPERFAMILY SSF142754 35 342 2.09E-100 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 SUPERFAMILY SSF52922 189 325 1.31E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 SUPERFAMILY SSF52518 4 193 5.89E-60 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 Gene3D G3DSA:3.40.50.920 196 326 3.2E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 Pfam PF02779 Transketolase, pyrimidine binding domain 5 174 8.1E-42 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 Pfam PF02780 Transketolase, C-terminal domain 195 317 2.1E-37 T 29-03-2018 IPR033248 Transketolase, C-terminal domain MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 Gene3D G3DSA:3.40.50.970 2 195 3.1E-61 T 29-03-2018 MSG_RS12555 f2812faa8546173cd6c2f6d2ad1130e9 332 SMART SM00861 6 179 1.7E-54 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 Gene3D G3DSA:3.40.1280.10 97 259 6.3E-43 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 Gene3D G3DSA:3.30.1330.30 2 96 1.2E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 28 97 4.9E-7 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 SUPERFAMILY SSF75217 100 259 2.09E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 SMART SM00967 28 100 1.4E-11 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 Pfam PF00588 SpoU rRNA Methylase family 111 253 6.0E-35 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MSG_RS11465 eb4cd1fd002e7822bbf2493282ac6644 265 SUPERFAMILY SSF55315 6 96 5.41E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS09120 d81ed67b148dc1ccaea3882376f7e21c 115 SUPERFAMILY SSF82607 17 101 3.27E-9 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS09120 d81ed67b148dc1ccaea3882376f7e21c 115 Pfam PF02575 YbaB/EbfC DNA-binding family 17 99 2.5E-10 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS09120 d81ed67b148dc1ccaea3882376f7e21c 115 Gene3D G3DSA:3.30.1310.10 5 104 4.2E-15 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS14890 c5605ee695c429bb6d382895a1ebfdd9 478 PIRSF PIRSF006060 14 478 1.3E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS14890 c5605ee695c429bb6d382895a1ebfdd9 478 ProSitePatterns PS00218 Amino acid permeases signature. 59 89 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MSG_RS14890 c5605ee695c429bb6d382895a1ebfdd9 478 Pfam PF00324 Amino acid permease 35 467 6.3E-98 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MSG_RS09355 a0a3f32d1895fc676d5daab453359547 474 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 89 447 1.2E-40 T 29-03-2018 IPR021145 Portal protein MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 SUPERFAMILY SSF55729 16 295 2.38E-52 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Pfam PF13527 Acetyltransferase (GNAT) domain 18 141 1.3E-24 T 29-03-2018 MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 SUPERFAMILY SSF55718 296 391 8.24E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Gene3D G3DSA:3.40.630.30 12 143 2.0E-14 T 29-03-2018 MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Hamap MF_01812 UPF0256 protein . 15 395 30.567 T 29-03-2018 IPR022902 N-acetyltransferase Eis MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Pfam PF13530 Sterol carrier protein domain 191 387 2.5E-38 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Gene3D G3DSA:3.30.1050.10 290 388 4.9E-22 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS16980 68739fbb0f59d79b5025e6d539bdf843 395 Gene3D G3DSA:3.40.630.30 144 289 9.6E-32 T 29-03-2018 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 SMART SM00919 176 396 1.2E-110 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 SMART SM01274 31 164 2.8E-72 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 SUPERFAMILY SSF53223 25 174 3.6E-50 T 29-03-2018 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 Pfam PF03949 Malic enzyme, NAD binding domain 178 395 1.5E-20 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 Pfam PF00390 Malic enzyme, N-terminal domain 35 127 4.3E-19 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 PRINTS PR00072 Malic enzyme signature 93 115 3.8E-6 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 PRINTS PR00072 Malic enzyme signature 203 219 3.8E-6 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 PRINTS PR00072 Malic enzyme signature 172 188 3.8E-6 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 Gene3D G3DSA:3.40.50.720 174 397 7.0E-67 T 29-03-2018 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 Gene3D G3DSA:3.40.50.10380 24 173 3.4E-31 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 PIRSF PIRSF000106 44 397 7.1E-68 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MSG_RS18720 f6db0f29de0e249fa2ab4dadfce6eee5 397 SUPERFAMILY SSF51735 176 395 1.41E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07960 c13350add849fe4519679b4e2511a8c1 198 SMART SM00756 11 152 1.2E-59 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 MSG_RS07960 c13350add849fe4519679b4e2511a8c1 198 Pfam PF07884 Vitamin K epoxide reductase family 16 148 4.7E-32 T 29-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 SUPERFAMILY SSF48498 82 201 1.1E-19 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 Gene3D G3DSA:1.10.10.60 2 67 1.0E-15 T 29-03-2018 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 Gene3D G3DSA:1.10.357.10 68 204 5.4E-16 T 29-03-2018 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 Pfam PF08360 QacR-like protein, C-terminal region 82 196 3.1E-4 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 8.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 SUPERFAMILY SSF46689 9 77 1.08E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS01565 5f039341f7fb754e4a1cadfae73fe6d6 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.2E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS10925 40e01182b3b3fb63e8faf4bee01f3972 372 SUPERFAMILY SSF51412 1 70 4.58E-50 T 29-03-2018 MSG_RS10925 40e01182b3b3fb63e8faf4bee01f3972 372 SUPERFAMILY SSF51412 118 366 4.58E-50 T 29-03-2018 MSG_RS10925 40e01182b3b3fb63e8faf4bee01f3972 372 Gene3D G3DSA:3.20.20.70 3 369 1.7E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS10925 40e01182b3b3fb63e8faf4bee01f3972 372 Pfam PF03060 Nitronate monooxygenase 22 359 5.8E-58 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 Gene3D G3DSA:3.40.50.980 193 391 7.9E-29 T 29-03-2018 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 Gene3D G3DSA:3.40.50.980 26 192 4.2E-29 T 29-03-2018 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 Gene3D G3DSA:3.30.300.30 491 604 1.0E-15 T 29-03-2018 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 SUPERFAMILY SSF56801 26 606 3.92E-101 T 29-03-2018 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 Pfam PF00501 AMP-binding enzyme 33 495 2.8E-74 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS22605 7b2c2e39853d133f6144575634ba804d 611 Gene3D G3DSA:2.30.38.10 392 488 8.1E-19 T 29-03-2018 MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 Gene3D G3DSA:3.40.50.1820 3 270 4.0E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 SUPERFAMILY SSF53474 14 270 7.97E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 Pfam PF12697 Alpha/beta hydrolase family 14 262 4.1E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 PRINTS PR00412 Epoxide hydrolase signature 244 266 4.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 PRINTS PR00412 Epoxide hydrolase signature 38 53 4.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22180 5dacf87c14c6761000f2be2ffb0f0c0a 274 PRINTS PR00412 Epoxide hydrolase signature 18 36 4.3E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Gene3D G3DSA:3.40.50.300 3 308 8.5E-24 T 29-03-2018 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Pfam PF12705 PD-(D/E)XK nuclease superfamily 794 1038 1.4E-41 T 29-03-2018 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Pfam PF13361 UvrD-like helicase C-terminal domain 309 683 5.4E-13 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 SUPERFAMILY SSF52540 11 706 1.07E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 300 3.1E-26 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Gene3D G3DSA:3.90.320.10 748 963 2.8E-12 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MSG_RS06275 d7f00c6a1fcbe23d102807c92b3d4183 1046 Gene3D G3DSA:3.40.50.300 341 719 1.4E-36 T 29-03-2018 MSG_RS22675 a1448f8436a51f505231b139dced5bc3 275 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS22675 a1448f8436a51f505231b139dced5bc3 275 Pfam PF00005 ABC transporter 34 182 1.1E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS22675 a1448f8436a51f505231b139dced5bc3 275 SMART SM00382 42 232 4.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS22675 a1448f8436a51f505231b139dced5bc3 275 Gene3D G3DSA:3.40.50.300 3 257 3.7E-47 T 29-03-2018 MSG_RS22675 a1448f8436a51f505231b139dced5bc3 275 SUPERFAMILY SSF52540 13 244 8.32E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 Gene3D G3DSA:3.40.50.1820 6 296 7.2E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 7.5E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 129 142 7.5E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 86 7.5E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 SUPERFAMILY SSF53474 23 292 9.97E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02445 27d9c96ef1bea5b76b165e70ed349524 298 Pfam PF12697 Alpha/beta hydrolase family 48 285 2.2E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS04170 0c7f7d9b7e6cdf5562be4810ece06931 206 SUPERFAMILY SSF109998 6 130 3.88E-6 T 29-03-2018 IPR027304 Trigger factor/SurA domain MSG_RS04170 0c7f7d9b7e6cdf5562be4810ece06931 206 Gene3D G3DSA:1.10.4030.10 3 139 1.3E-6 T 29-03-2018 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 Pfam PF01386 Ribosomal L25p family 9 95 5.3E-23 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 Gene3D G3DSA:2.170.120.20 102 187 8.5E-17 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 7 183 23.098 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 Gene3D G3DSA:2.40.240.10 7 97 2.4E-27 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 181 3.6E-15 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 SUPERFAMILY SSF50715 8 187 4.01E-45 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 9 180 4.1E-56 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MSG_RS19905 f61d693c808a6c6f6d8b923ac59eb1f3 218 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 95 4.0E-39 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 28 348 1.6E-93 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 PIRSF PIRSF002756 4 351 3.5E-99 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 Gene3D G3DSA:3.40.190.10 206 354 8.7E-14 T 29-03-2018 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 Gene3D G3DSA:3.40.190.10 27 194 6.0E-30 T 29-03-2018 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 SUPERFAMILY SSF53850 28 352 2.08E-79 T 29-03-2018 MSG_RS04520 a85b5b8794264aef905cc86822ffbe37 360 Pfam PF12849 PBP superfamily domain 25 315 9.6E-51 T 29-03-2018 IPR024370 PBP domain MSG_RS22705 12cf283138249214f5724d111c495bc7 477 Pfam PF00890 FAD binding domain 102 198 1.2E-4 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS22705 12cf283138249214f5724d111c495bc7 477 Gene3D G3DSA:3.50.50.60 7 456 6.6E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22705 12cf283138249214f5724d111c495bc7 477 SUPERFAMILY SSF51905 312 359 2.16E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS22705 12cf283138249214f5724d111c495bc7 477 SUPERFAMILY SSF51905 8 206 2.16E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS09205 f2c5e8db61d638b7fada78f2f29e04b5 183 SUPERFAMILY SSF55729 7 182 2.96E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS09205 f2c5e8db61d638b7fada78f2f29e04b5 183 Pfam PF00583 Acetyltransferase (GNAT) family 49 157 9.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS09205 f2c5e8db61d638b7fada78f2f29e04b5 183 Gene3D G3DSA:3.40.630.30 5 183 3.8E-33 T 29-03-2018 MSG_RS06265 0919f850c2bf931dd5bcb5d04992b7c6 102 Gene3D G3DSA:1.10.10.10 4 98 6.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06265 0919f850c2bf931dd5bcb5d04992b7c6 102 SUPERFAMILY SSF46767 6 82 4.58E-16 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS06265 0919f850c2bf931dd5bcb5d04992b7c6 102 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 10 82 1.1E-17 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MSG_RS15845 fd2a537e168631bf6baf2603c3f2c39d 187 SUPERFAMILY SSF54427 16 142 6.36E-25 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS15845 fd2a537e168631bf6baf2603c3f2c39d 187 Gene3D G3DSA:3.10.450.50 11 144 1.0E-21 T 29-03-2018 MSG_RS15845 fd2a537e168631bf6baf2603c3f2c39d 187 Pfam PF07366 SnoaL-like polyketide cyclase 21 142 2.1E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS10575 e8f739f7514b58bd2728b3fa039a52ee 394 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 100 378 6.1E-79 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MSG_RS10575 e8f739f7514b58bd2728b3fa039a52ee 394 SUPERFAMILY SSF101960 29 387 6.54E-87 T 29-03-2018 MSG_RS10575 e8f739f7514b58bd2728b3fa039a52ee 394 Pfam PF01458 Uncharacterized protein family (UPF0051) 135 361 2.7E-67 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MSG_RS22385 50e9ff3167dc52b02827136e9aef0678 343 SUPERFAMILY SSF51679 1 340 4.19E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS22385 50e9ff3167dc52b02827136e9aef0678 343 Gene3D G3DSA:3.20.20.30 1 343 1.1E-70 T 29-03-2018 MSG_RS22385 50e9ff3167dc52b02827136e9aef0678 343 Pfam PF00296 Luciferase-like monooxygenase 14 324 3.5E-72 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS22385 50e9ff3167dc52b02827136e9aef0678 343 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 329 7.3E-153 T 29-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 170 9.1E-7 T 29-03-2018 MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 Gene3D G3DSA:3.40.50.720 3 236 1.4E-73 T 29-03-2018 MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 233 1.0E-59 T 29-03-2018 MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 1.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 126 154 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 SUPERFAMILY SSF51735 4 234 6.59E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 127 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23605 e2b3b0d250f2350361d1089f5d86568b 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 158 2.6E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Pfam PF13247 4Fe-4S dicluster domain 196 235 2.8E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Pfam PF13247 4Fe-4S dicluster domain 122 181 8.6E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 PIRSF PIRSF036298 16 322 5.9E-55 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Gene3D G3DSA:3.30.70.20 202 317 4.1E-19 T 29-03-2018 MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Gene3D G3DSA:3.30.70.20 37 145 1.6E-36 T 29-03-2018 MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 SUPERFAMILY SSF54862 20 296 1.36E-57 T 29-03-2018 MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 162 173 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Gene3D G3DSA:3.30.70.20 12 36 0.012 T 29-03-2018 MSG_RS00715 a3ffc640e77554dea40ee3ddde7f49a6 324 Gene3D G3DSA:3.30.70.20 146 201 1.9E-14 T 29-03-2018 MSG_RS24035 2f466f8bd3d1466c2390f63503cb65ab 180 Pfam PF10759 Protein of unknown function (DUF2587) 33 167 2.7E-77 T 29-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 SUPERFAMILY SSF51905 1 165 3.27E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 SUPERFAMILY SSF51905 263 365 3.27E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-16 T 29-03-2018 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.4E-16 T 29-03-2018 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.4E-16 T 29-03-2018 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.4E-16 T 29-03-2018 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 Gene3D G3DSA:3.50.50.60 1 342 4.2E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15125 0f896674c7d495a703df97e48d853ca8 380 Pfam PF01494 FAD binding domain 3 333 2.6E-19 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 Pfam PF01022 Bacterial regulatory protein, arsR family 19 64 2.3E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 Gene3D G3DSA:1.10.10.10 2 98 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 9.0E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 9.0E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 9.0E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 SMART SM00418 12 90 4.3E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MSG_RS06005 5136a0b7fd53fd8226a672b8bf501170 102 SUPERFAMILY SSF46785 9 88 9.79E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00170 c2a831b2e43570b590990108d7065353 328 Pfam PF05726 Pirin C-terminal cupin domain 186 284 3.5E-10 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MSG_RS00170 c2a831b2e43570b590990108d7065353 328 Pfam PF02678 Pirin 38 134 9.3E-26 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MSG_RS00170 c2a831b2e43570b590990108d7065353 328 Gene3D G3DSA:2.60.120.10 32 260 1.4E-52 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS00170 c2a831b2e43570b590990108d7065353 328 SUPERFAMILY SSF51182 37 295 1.33E-58 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS00170 c2a831b2e43570b590990108d7065353 328 PIRSF PIRSF006232 17 297 1.0E-63 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 Gene3D G3DSA:3.10.25.10 204 309 7.1E-20 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 SUPERFAMILY SSF50486 206 304 1.52E-18 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 SUPERFAMILY SSF53328 1 203 5.23E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 130 153 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 Gene3D G3DSA:3.40.50.170 1 203 1.0E-51 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 Pfam PF00551 Formyl transferase 1 169 6.2E-30 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS05005 f649de2c44d789da1512792c0e24ea68 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 303 3.7E-16 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 Gene3D G3DSA:1.20.144.10 20 187 1.8E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 SUPERFAMILY SSF111331 213 492 1.44E-51 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 SMART SM00014 75 184 1.3E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 Pfam PF01569 PAP2 superfamily 80 185 6.3E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 Pfam PF00781 Diacylglycerol kinase catalytic domain 214 326 6.2E-19 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 SUPERFAMILY SSF48317 19 192 1.7E-36 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 Gene3D G3DSA:3.40.50.10330 206 333 3.8E-21 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MSG_RS02550 af6e0290c54e0ba2ea51cfcc574c5583 496 SMART SM00046 213 327 2.6E-6 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MSG_RS01730 3ac95f108af54ae3a7fd86bf2917aa4a 346 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 148 275 1.1E-6 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS01730 3ac95f108af54ae3a7fd86bf2917aa4a 346 Gene3D G3DSA:1.10.287.950 167 291 9.3E-5 T 29-03-2018 MSG_RS01730 3ac95f108af54ae3a7fd86bf2917aa4a 346 Pfam PF02470 MlaD protein 36 112 1.9E-17 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS01730 3ac95f108af54ae3a7fd86bf2917aa4a 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 6.3E-84 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS11890 11249732a292b4915eda035b94c97ff9 128 Pfam PF14087 Domain of unknown function (DUF4267) 16 123 2.3E-22 T 29-03-2018 IPR025363 Protein of unknown function DUF4267 MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 Gene3D G3DSA:3.40.50.720 1 217 6.2E-49 T 29-03-2018 MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 Pfam PF00106 short chain dehydrogenase 8 180 4.1E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 SUPERFAMILY SSF51735 1 204 7.06E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 1.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01005 b000169d24687efc795f78b819f79b5d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.4E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 Gene3D G3DSA:1.10.357.10 68 200 1.0E-13 T 29-03-2018 MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 Gene3D G3DSA:1.10.10.60 7 67 1.6E-17 T 29-03-2018 MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 1.2E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 SUPERFAMILY SSF46689 10 85 3.14E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14820 30664bc1bfcfef3b1b8107bc520e09e1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.0E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS13410 d6cb45d5f2dd7eda1317432c05350cd2 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 148 1.4E-21 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS13410 d6cb45d5f2dd7eda1317432c05350cd2 151 Gene3D G3DSA:3.30.530.20 1 151 3.4E-19 T 29-03-2018 IPR023393 START-like domain MSG_RS13410 d6cb45d5f2dd7eda1317432c05350cd2 151 SUPERFAMILY SSF55961 7 144 7.54E-18 T 29-03-2018 MSG_RS13435 c6a7ef8f6e34bc006a1c9b4cd0094094 255 Pfam PF09844 Uncharacterized conserved protein (COG2071) 34 244 3.2E-59 T 29-03-2018 IPR018644 Protein of unknown function DUF2071 MSG_RS13435 c6a7ef8f6e34bc006a1c9b4cd0094094 255 SUPERFAMILY SSF160104 18 160 1.26E-8 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 MSG_RS13435 c6a7ef8f6e34bc006a1c9b4cd0094094 255 Gene3D G3DSA:2.40.400.10 16 246 2.2E-24 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 MSG_RS06070 d0fdc2eba125026373a5c0a09a0b4647 258 SUPERFAMILY SSF143081 2 247 4.84E-63 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) MSG_RS06070 d0fdc2eba125026373a5c0a09a0b4647 258 Pfam PF02586 SOS response associated peptidase (SRAP) 1 236 1.9E-64 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) MSG_RS06070 d0fdc2eba125026373a5c0a09a0b4647 258 Gene3D G3DSA:3.90.1680.10 1 256 1.3E-74 T 29-03-2018 IPR003738 SOS response associated peptidase (SRAP) MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 SMART SM00448 1 112 1.7E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 SUPERFAMILY SSF52172 2 182 2.85E-44 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 Pfam PF00072 Response regulator receiver domain 3 112 1.4E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 3.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 Gene3D G3DSA:1.10.10.10 123 227 1.9E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 SMART SM00862 148 223 1.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MSG_RS20240 afbb5abc35a8f64e1628df02f181fa7c 228 Gene3D G3DSA:3.40.50.2300 1 122 8.8E-42 T 29-03-2018 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 Pfam PF03466 LysR substrate binding domain 87 292 6.7E-29 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.2E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 Gene3D G3DSA:3.40.190.10 88 176 1.7E-13 T 29-03-2018 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 Gene3D G3DSA:3.40.190.10 177 268 5.8E-14 T 29-03-2018 MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 SUPERFAMILY SSF46785 3 87 5.39E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 Gene3D G3DSA:1.10.10.10 1 83 3.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01205 08e550efb7f79cdcbc94fbc04d597586 310 SUPERFAMILY SSF53850 88 294 3.08E-30 T 29-03-2018 MSG_RS04090 9f86517475b279e4a7e9f62bdae17ed4 166 SUPERFAMILY SSF54637 15 147 1.91E-29 T 29-03-2018 IPR029069 HotDog domain MSG_RS04090 9f86517475b279e4a7e9f62bdae17ed4 166 Hamap MF_00799 UPF0336 protein . 1 148 32.593 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS04090 9f86517475b279e4a7e9f62bdae17ed4 166 PIRSF PIRSF018072 1 150 6.9E-50 T 29-03-2018 IPR016709 Uncharacterised protein family UPF0336 MSG_RS04090 9f86517475b279e4a7e9f62bdae17ed4 166 Pfam PF13452 N-terminal half of MaoC dehydratase 13 136 5.6E-29 T 29-03-2018 MSG_RS04090 9f86517475b279e4a7e9f62bdae17ed4 166 Gene3D G3DSA:3.10.129.10 7 151 9.6E-28 T 29-03-2018 MSG_RS10215 5ffc39fbbf81c1dc5ccfd78833205277 191 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 10 187 35.168 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MSG_RS10215 5ffc39fbbf81c1dc5ccfd78833205277 191 Pfam PF00156 Phosphoribosyl transferase domain 22 160 4.0E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS10215 5ffc39fbbf81c1dc5ccfd78833205277 191 Gene3D G3DSA:3.40.50.2020 6 190 4.9E-32 T 29-03-2018 MSG_RS10215 5ffc39fbbf81c1dc5ccfd78833205277 191 SUPERFAMILY SSF53271 12 181 7.34E-39 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS16400 c4908494a7cfe857f8474590d1351f32 505 Pfam PF01523 Putative modulator of DNA gyrase 34 345 6.1E-52 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MSG_RS16400 c4908494a7cfe857f8474590d1351f32 505 SUPERFAMILY SSF111283 17 496 1.23E-93 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MSG_RS16400 c4908494a7cfe857f8474590d1351f32 505 Gene3D G3DSA:3.30.2290.10 15 243 3.2E-47 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PIRSF PIRSF001467 6 182 1.4E-59 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 Gene3D G3DSA:2.40.100.10 2 182 2.9E-65 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 66 83 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 SUPERFAMILY SSF50891 16 181 6.28E-62 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 17 180 9.2E-48 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 30 45 2.8E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 111 126 2.8E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 126 138 2.8E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 71 83 2.8E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS00075 8556efff5b5f31a1bac2681cdbd95a5c 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 139 154 2.8E-25 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 Gene3D G3DSA:1.10.357.10 10 216 2.7E-29 T 29-03-2018 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 4.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 SUPERFAMILY SSF46689 17 82 7.56E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS07315 4e98a03574edda6588dbdcd36196cace 216 SUPERFAMILY SSF48498 92 212 2.51E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21830 c1cc255c37fb74f225972f97be75628e 339 SUPERFAMILY SSF54909 5 306 8.58E-102 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS21830 c1cc255c37fb74f225972f97be75628e 339 Pfam PF04261 Dyp-type peroxidase family 7 303 2.1E-98 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MSG_RS21830 c1cc255c37fb74f225972f97be75628e 339 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 7 303 8.8E-85 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MSG_RS21830 c1cc255c37fb74f225972f97be75628e 339 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 326 336 0.067 T 29-03-2018 MSG_RS04195 0ac1c101ee08f82e3a396c497debdded 503 Pfam PF03055 Retinal pigment epithelial membrane protein 19 501 1.5E-102 T 29-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 MSG_RS04195 0ac1c101ee08f82e3a396c497debdded 503 Gene3D G3DSA:2.60.40.10 18 210 0.0026 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS22680 2747bbc8cac006b6a2c2f0ad312549f4 286 Pfam PF00950 ABC 3 transport family 24 274 1.1E-39 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MSG_RS22680 2747bbc8cac006b6a2c2f0ad312549f4 286 Gene3D G3DSA:1.10.3470.10 1 286 1.1E-24 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MSG_RS22680 2747bbc8cac006b6a2c2f0ad312549f4 286 SUPERFAMILY SSF81345 12 273 3.01E-30 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MSG_RS21130 cbf4b692b558860ca0f9dae4945312f5 269 Pfam PF02405 Permease MlaE 49 261 7.3E-56 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS16935 87693a8967c91fc9ccfa6562c1d3638b 279 Pfam PF01841 Transglutaminase-like superfamily 127 232 2.5E-22 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS16935 87693a8967c91fc9ccfa6562c1d3638b 279 SUPERFAMILY SSF54001 9 268 4.63E-33 T 29-03-2018 MSG_RS16935 87693a8967c91fc9ccfa6562c1d3638b 279 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 4 82 4.2E-18 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MSG_RS16935 87693a8967c91fc9ccfa6562c1d3638b 279 Gene3D G3DSA:3.90.260.10 163 272 2.7E-6 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS16935 87693a8967c91fc9ccfa6562c1d3638b 279 SMART SM00460 167 234 8.4E-16 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS02150 af10ff197b8609923c770a5c73ceddf5 379 Gene3D G3DSA:3.20.20.300 42 373 1.5E-58 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS02150 af10ff197b8609923c770a5c73ceddf5 379 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 368 9.2E-84 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MSG_RS02150 af10ff197b8609923c770a5c73ceddf5 379 SUPERFAMILY SSF51445 59 371 1.16E-59 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS06645 f70d880d256ce451ddc1eccc08c789d4 452 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 6 431 1.6E-162 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS06645 f70d880d256ce451ddc1eccc08c789d4 452 Gene3D G3DSA:3.20.20.30 1 452 4.1E-109 T 29-03-2018 MSG_RS06645 f70d880d256ce451ddc1eccc08c789d4 452 PIRSF PIRSF000337 1 443 1.3E-141 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS06645 f70d880d256ce451ddc1eccc08c789d4 452 Pfam PF00296 Luciferase-like monooxygenase 33 389 1.5E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS06645 f70d880d256ce451ddc1eccc08c789d4 452 SUPERFAMILY SSF51679 4 437 1.31E-122 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS18640 7083aef867b10e167bdb553dfcb46176 56 Gene3D G3DSA:2.60.120.260 1 51 5.0E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS18640 7083aef867b10e167bdb553dfcb46176 56 SUPERFAMILY SSF49785 1 51 1.02E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like MSG_RS13850 b9f92fd2182d53784ed6829ce10f217f 509 SUPERFAMILY SSF52540 331 456 1.68E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS13850 b9f92fd2182d53784ed6829ce10f217f 509 Gene3D G3DSA:3.90.1200.10 115 330 1.5E-9 T 29-03-2018 MSG_RS13850 b9f92fd2182d53784ed6829ce10f217f 509 Pfam PF13671 AAA domain 330 456 5.7E-17 T 29-03-2018 MSG_RS13850 b9f92fd2182d53784ed6829ce10f217f 509 Gene3D G3DSA:3.40.50.300 331 504 2.4E-20 T 29-03-2018 MSG_RS13850 b9f92fd2182d53784ed6829ce10f217f 509 SUPERFAMILY SSF56112 26 293 6.56E-14 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 TIGRFAM TIGR01068 thioredoxin: thioredoxin 14 111 2.1E-39 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 PRINTS PR00421 Thioredoxin family signature 37 46 1.1E-8 T 29-03-2018 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 PRINTS PR00421 Thioredoxin family signature 29 37 1.1E-8 T 29-03-2018 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 PRINTS PR00421 Thioredoxin family signature 77 88 1.1E-8 T 29-03-2018 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 SUPERFAMILY SSF52833 10 113 2.76E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 Pfam PF00085 Thioredoxin 11 109 1.4E-32 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 Gene3D G3DSA:3.40.30.10 1 116 3.0E-35 T 29-03-2018 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 PIRSF PIRSF000077 7 113 2.9E-44 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MSG_RS24665 80ccfca97e00fb42d96b80e46a99afa7 117 ProSitePatterns PS00194 Thioredoxin family active site. 30 48 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 Pfam PF04542 Sigma-70 region 2 35 105 6.2E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 SUPERFAMILY SSF88946 14 123 1.53E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 SUPERFAMILY SSF88659 120 191 7.66E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 Gene3D G3DSA:1.10.10.10 116 198 2.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 Gene3D G3DSA:1.10.1740.10 9 115 1.4E-18 T 29-03-2018 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 190 5.9E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 59 91 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS05100 33b1ec15977b0842c5479c5805901e11 198 Pfam PF08281 Sigma-70, region 4 138 187 2.2E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS15985 657fffb7c30a2d438c7806fb3bbf4b05 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 57 8.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS15985 657fffb7c30a2d438c7806fb3bbf4b05 210 Gene3D G3DSA:1.10.357.10 58 201 1.4E-17 T 29-03-2018 MSG_RS15985 657fffb7c30a2d438c7806fb3bbf4b05 210 SUPERFAMILY SSF46689 3 76 2.44E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS15985 657fffb7c30a2d438c7806fb3bbf4b05 210 Gene3D G3DSA:1.10.10.60 2 57 1.3E-14 T 29-03-2018 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 SUPERFAMILY SSF51206 23 158 1.57E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 Gene3D G3DSA:1.10.10.10 162 241 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 SUPERFAMILY SSF46785 163 239 7.81E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 Gene3D G3DSA:2.60.120.10 18 161 1.7E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 PRINTS PR00103 cAMP-dependent protein kinase signature 64 78 3.8E-6 T 29-03-2018 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 PRINTS PR00103 cAMP-dependent protein kinase signature 94 103 3.8E-6 T 29-03-2018 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 PRINTS PR00103 cAMP-dependent protein kinase signature 106 117 3.8E-6 T 29-03-2018 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 PRINTS PR00103 cAMP-dependent protein kinase signature 49 63 3.8E-6 T 29-03-2018 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 Pfam PF00027 Cyclic nucleotide-binding domain 48 133 2.5E-21 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 SMART SM00100 28 146 3.3E-23 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 Pfam PF13545 Crp-like helix-turn-helix domain 167 238 4.8E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MSG_RS24140 a1cf9fb90930a8e4a864836e80659ac3 262 SMART SM00419 185 233 2.4E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MSG_RS12625 7c6fd2ce8c3f017b4e54d2ceede0d9a9 720 Pfam PF02446 4-alpha-glucanotransferase 180 684 1.7E-114 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS12625 7c6fd2ce8c3f017b4e54d2ceede0d9a9 720 Gene3D G3DSA:3.20.20.80 169 700 2.5E-168 T 29-03-2018 MSG_RS12625 7c6fd2ce8c3f017b4e54d2ceede0d9a9 720 SUPERFAMILY SSF51445 172 600 1.19E-136 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS12625 7c6fd2ce8c3f017b4e54d2ceede0d9a9 720 SUPERFAMILY SSF51445 629 705 1.19E-136 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS12625 7c6fd2ce8c3f017b4e54d2ceede0d9a9 720 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 133 687 3.2E-87 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MSG_RS11725 acef3514917472de5d278f4acb5ada4e 207 Pfam PF00293 NUDIX domain 45 156 1.0E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS11725 acef3514917472de5d278f4acb5ada4e 207 Gene3D G3DSA:3.90.79.10 2 185 1.1E-35 T 29-03-2018 MSG_RS11725 acef3514917472de5d278f4acb5ada4e 207 SUPERFAMILY SSF55811 8 178 4.33E-44 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 291 1.6E-23 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 PIRSF PIRSF000103 3 300 2.5E-47 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 Gene3D G3DSA:3.40.50.720 2 178 2.2E-20 T 29-03-2018 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 SUPERFAMILY SSF51735 12 173 7.43E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 SUPERFAMILY SSF48179 169 294 5.55E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 168 2.9E-18 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MSG_RS01420 eb4c0024a17db926e08cdc4e8c86a5b1 320 Gene3D G3DSA:1.10.1040.10 179 296 2.5E-26 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MSG_RS15060 fb6df8df52ac367996d3b0437eba92b6 218 Pfam PF04472 Cell division protein SepF 130 201 2.5E-24 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 MSG_RS15060 fb6df8df52ac367996d3b0437eba92b6 218 Hamap MF_01197 Cell division protein SepF [sepF]. 1 209 21.101 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 MSG_RS19570 1699908e4142f36fb94d415a2c1ef1dc 275 Pfam PF03405 Fatty acid desaturase 12 269 2.9E-32 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS19570 1699908e4142f36fb94d415a2c1ef1dc 275 SUPERFAMILY SSF47240 1 271 1.01E-57 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS19570 1699908e4142f36fb94d415a2c1ef1dc 275 Gene3D G3DSA:1.10.620.20 1 272 2.1E-50 T 29-03-2018 MSG_RS19570 1699908e4142f36fb94d415a2c1ef1dc 275 PIRSF PIRSF000346 1 272 5.7E-72 T 29-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 263 271 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 SUPERFAMILY SSF52343 99 224 8.12E-21 T 29-03-2018 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 235 304 6.8E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 Gene3D G3DSA:3.10.20.30 217 313 1.5E-20 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 SUPERFAMILY SSF63380 4 98 9.59E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 Gene3D G3DSA:2.40.30.10 2 99 4.3E-12 T 29-03-2018 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 186 194 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 30 40 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 89 103 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 89 2.3E-24 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 SUPERFAMILY SSF54292 208 309 8.78E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MSG_RS09980 f7da314bef626a4a471d45d527361ac0 314 Gene3D G3DSA:3.40.50.80 101 216 1.8E-15 T 29-03-2018 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 SUPERFAMILY SSF52172 16 140 7.54E-27 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 Pfam PF00072 Response regulator receiver domain 19 127 9.7E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 SMART SM00448 16 129 3.9E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 Gene3D G3DSA:3.60.40.10 140 395 4.4E-18 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 Gene3D G3DSA:3.40.50.2300 11 139 2.0E-28 T 29-03-2018 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 SMART SM00331 172 393 1.2E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS05740 7efde4f7dbe0f289cc949a2e3c22a7dc 395 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 393 1.1E-29 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 SUPERFAMILY SSF54506 2 259 2.97E-66 T 29-03-2018 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 Gene3D G3DSA:3.10.310.10 121 248 5.4E-33 T 29-03-2018 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 Gene3D G3DSA:3.10.310.10 1 120 1.1E-28 T 29-03-2018 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 Pfam PF02567 Phenazine biosynthesis-like protein 6 256 6.2E-51 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 PIRSF PIRSF016184 1 260 8.2E-44 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS00145 15fbf0483fd82eb588a4fc248d8c817c 265 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 257 1.2E-29 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MSG_RS09735 3f7e1d36bb49a8ccc82fae7b1e530902 300 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 228 243 9.1E-7 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS09735 3f7e1d36bb49a8ccc82fae7b1e530902 300 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 148 163 9.1E-7 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS09735 3f7e1d36bb49a8ccc82fae7b1e530902 300 Gene3D G3DSA:2.40.100.10 117 299 2.9E-38 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS09735 3f7e1d36bb49a8ccc82fae7b1e530902 300 SUPERFAMILY SSF50891 135 298 3.65E-34 T 29-03-2018 IPR029000 Cyclophilin-like domain MSG_RS09735 3f7e1d36bb49a8ccc82fae7b1e530902 300 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 136 296 1.8E-24 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MSG_RS09775 ff2dcc8b6a337d5fc421d22666300238 128 PIRSF PIRSF021591 1 128 2.4E-54 T 29-03-2018 IPR016793 Uncharacterised conserved protein UCP021591 MSG_RS02245 a1b9a8bfd2ddbc958a4e4cf37fb5deb3 250 Pfam PF01903 CbiX 124 215 9.6E-9 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MSG_RS02245 a1b9a8bfd2ddbc958a4e4cf37fb5deb3 250 Pfam PF01903 CbiX 8 104 1.6E-14 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MSG_RS02245 a1b9a8bfd2ddbc958a4e4cf37fb5deb3 250 SUPERFAMILY SSF53800 3 221 6.3E-28 T 29-03-2018 MSG_RS02245 a1b9a8bfd2ddbc958a4e4cf37fb5deb3 250 Gene3D G3DSA:3.40.50.1400 115 226 1.2E-17 T 29-03-2018 MSG_RS02245 a1b9a8bfd2ddbc958a4e4cf37fb5deb3 250 Gene3D G3DSA:3.40.50.1400 1 114 8.7E-23 T 29-03-2018 MSG_RS10310 81b1a8bc70105f71e0f7835c0ee424c5 650 Hamap MF_00983 Probable primosomal protein N' [priA]. 1 649 21.317 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MSG_RS20910 99038a2c4fa638049a4fef7d46e9bb86 327 Gene3D G3DSA:3.20.20.30 1 327 5.6E-81 T 29-03-2018 MSG_RS20910 99038a2c4fa638049a4fef7d46e9bb86 327 SUPERFAMILY SSF51679 1 326 3.42E-79 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20910 99038a2c4fa638049a4fef7d46e9bb86 327 Pfam PF00296 Luciferase-like monooxygenase 1 299 1.1E-51 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS20910 99038a2c4fa638049a4fef7d46e9bb86 327 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 16 235 4.4E-85 T 29-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 SUPERFAMILY SSF50615 14 97 2.35E-24 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 SUPERFAMILY SSF47917 383 511 8.11E-47 T 29-03-2018 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 49.801 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 4.2E-16 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 SUPERFAMILY SSF52540 99 381 7.38E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 PIRSF PIRSF039088 4 514 1.2E-233 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.2E-253 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 7.2E-69 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Gene3D G3DSA:2.40.30.20 6 85 1.4E-30 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Gene3D G3DSA:3.40.50.300 86 375 2.5E-107 T 29-03-2018 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.2E-48 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18255 21ea4c043d28de3c134e29b33e048854 550 Gene3D G3DSA:1.20.150.20 384 511 6.7E-52 T 29-03-2018 MSG_RS12520 82045699f077080d194dacdab93bf039 85 SUPERFAMILY SSF50090 23 83 7.85E-6 T 29-03-2018 IPR008990 Electron transport accessory protein-like domain MSG_RS12520 82045699f077080d194dacdab93bf039 85 Gene3D G3DSA:1.10.472.20 6 85 1.6E-9 T 29-03-2018 MSG_RS19385 a6cde86a6d40b635d6164bdc506e536d 143 Pfam PF00011 Hsp20/alpha crystallin family 43 139 2.5E-22 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MSG_RS19385 a6cde86a6d40b635d6164bdc506e536d 143 SUPERFAMILY SSF49764 15 129 4.53E-26 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS19385 a6cde86a6d40b635d6164bdc506e536d 143 Gene3D G3DSA:2.60.40.790 27 140 1.1E-25 T 29-03-2018 IPR008978 HSP20-like chaperone MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 376 2.0E-27 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 SUPERFAMILY SSF55961 169 377 2.59E-31 T 29-03-2018 MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 SUPERFAMILY SSF50022 21 164 2.36E-36 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 Gene3D G3DSA:3.90.380.10 155 376 7.7E-36 T 29-03-2018 MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 Pfam PF00355 Rieske [2Fe-2S] domain 54 134 1.4E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17650 c38a6a7dc12ece1ec3e50baa57297b55 378 Gene3D G3DSA:2.102.10.10 52 154 4.7E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS10785 2c3825a4426b5630a3d82d5dc6e52d3e 365 Pfam PF01757 Acyltransferase family 12 328 1.6E-15 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS04405 352935636069a62658ca9ae1543c999d 110 Pfam PF05666 Fels-1 Prophage Protein-like 66 110 1.0E-8 T 29-03-2018 IPR008617 Uncharacterised protein family, YcgJ MSG_RS04405 352935636069a62658ca9ae1543c999d 110 Pfam PF05666 Fels-1 Prophage Protein-like 16 53 1.7E-12 T 29-03-2018 IPR008617 Uncharacterised protein family, YcgJ MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 Gene3D G3DSA:3.40.309.10 268 461 3.2E-71 T 29-03-2018 MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 SUPERFAMILY SSF53720 8 476 1.7E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 Pfam PF00171 Aldehyde dehydrogenase family 24 475 6.6E-166 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 Gene3D G3DSA:3.40.605.10 1 267 2.0E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS04225 96a9c7a7898d6d81671fc2771dc4344e 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS18050 1997fcbd4dc368069e5e78ad5728443a 210 Pfam PF13523 Acetyltransferase (GNAT) domain 50 193 5.8E-43 T 29-03-2018 MSG_RS18050 1997fcbd4dc368069e5e78ad5728443a 210 Gene3D G3DSA:3.40.630.30 1 209 1.9E-20 T 29-03-2018 MSG_RS18050 1997fcbd4dc368069e5e78ad5728443a 210 SUPERFAMILY SSF55729 13 206 1.35E-48 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS18050 1997fcbd4dc368069e5e78ad5728443a 210 SMART SM01006 46 92 1.9E-9 T 29-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain MSG_RS10775 4da3135daff634bfd3b62c843b33b1df 303 SUPERFAMILY SSF52540 1 38 7.77E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10775 4da3135daff634bfd3b62c843b33b1df 303 SUPERFAMILY SSF52540 81 202 7.77E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10775 4da3135daff634bfd3b62c843b33b1df 303 Gene3D G3DSA:3.40.50.300 1 217 4.0E-13 T 29-03-2018 MSG_RS24375 9fd2d900e4ac8a3a70e00af34fd98ee5 489 SUPERFAMILY SSF51905 1 388 1.98E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24375 9fd2d900e4ac8a3a70e00af34fd98ee5 489 Gene3D G3DSA:3.50.50.60 166 458 9.4E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24375 9fd2d900e4ac8a3a70e00af34fd98ee5 489 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 57 3.1E-7 T 29-03-2018 MSG_RS24375 9fd2d900e4ac8a3a70e00af34fd98ee5 489 Gene3D G3DSA:3.50.50.60 5 165 7.4E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24375 9fd2d900e4ac8a3a70e00af34fd98ee5 489 Pfam PF00743 Flavin-binding monooxygenase-like 80 344 2.0E-9 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS19705 7e2f6c20e0b78aef5f545e92d982b1ca 289 Gene3D G3DSA:3.40.1090.10 2 209 1.5E-27 T 29-03-2018 MSG_RS19705 7e2f6c20e0b78aef5f545e92d982b1ca 289 SUPERFAMILY SSF52151 4 75 3.14E-26 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS19705 7e2f6c20e0b78aef5f545e92d982b1ca 289 SUPERFAMILY SSF52151 112 216 3.14E-26 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS19705 7e2f6c20e0b78aef5f545e92d982b1ca 289 Pfam PF01734 Patatin-like phospholipase 7 206 3.2E-18 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MSG_RS10780 8f3250bdbdae1163aa94dfa45ed44102 277 SUPERFAMILY SSF53335 85 142 1.33E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10780 8f3250bdbdae1163aa94dfa45ed44102 277 SUPERFAMILY SSF53335 183 249 1.33E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS10780 8f3250bdbdae1163aa94dfa45ed44102 277 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 8 277 7.5E-106 T 29-03-2018 IPR008884 Macrocin-O-methyltransferase MSG_RS10780 8f3250bdbdae1163aa94dfa45ed44102 277 Gene3D G3DSA:3.40.50.150 57 269 9.5E-10 T 29-03-2018 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 SUPERFAMILY SSF46894 140 205 1.77E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 Pfam PF00072 Response regulator receiver domain 10 116 2.8E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 205 6.4E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 Gene3D G3DSA:3.40.50.2300 7 136 3.7E-19 T 29-03-2018 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 SUPERFAMILY SSF52172 7 144 7.68E-19 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 SMART SM00421 156 213 2.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 6.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 6.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 6.1E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 SMART SM00448 8 128 3.0E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS06950 5ea08921da29b2e619d9d2088a8412cb 226 Gene3D G3DSA:1.10.10.10 137 226 1.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS18885 28641ce977c413f610910ca7b8ed3300 186 SUPERFAMILY SSF102405 10 182 1.83E-52 T 29-03-2018 MSG_RS18885 28641ce977c413f610910ca7b8ed3300 186 Gene3D G3DSA:3.40.50.450 3 185 1.5E-50 T 29-03-2018 MSG_RS18885 28641ce977c413f610910ca7b8ed3300 186 Pfam PF03641 Possible lysine decarboxylase 54 183 8.6E-37 T 29-03-2018 IPR031100 LOG family MSG_RS18885 28641ce977c413f610910ca7b8ed3300 186 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 11 185 2.1E-66 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MSG_RS10545 0f272dc06eb4c9ec0b177793e31a1ff0 264 Gene3D G3DSA:3.60.15.10 1 257 9.1E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10545 0f272dc06eb4c9ec0b177793e31a1ff0 264 SUPERFAMILY SSF56281 1 77 3.25E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10545 0f272dc06eb4c9ec0b177793e31a1ff0 264 SUPERFAMILY SSF56281 114 236 3.25E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10545 0f272dc06eb4c9ec0b177793e31a1ff0 264 Pfam PF12706 Beta-lactamase superfamily domain 38 223 5.8E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00412 Epoxide hydrolase signature 252 274 3.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00412 Epoxide hydrolase signature 219 235 3.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00412 Epoxide hydrolase signature 29 47 3.8E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 Pfam PF00561 alpha/beta hydrolase fold 24 263 1.5E-30 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 Gene3D G3DSA:3.40.50.1820 2 286 4.7E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 2.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13605 d2e6014564dfc74e3997d257c28f02d3 293 SUPERFAMILY SSF53474 5 278 6.51E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.3E-20 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 SUPERFAMILY SSF51735 1 245 8.27E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 Gene3D G3DSA:3.40.50.720 1 248 1.9E-56 T 29-03-2018 MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 203 8.6E-6 T 29-03-2018 MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 4.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS01525 9ae8399ad5efb1ed759c25e317c8c8e3 287 Pfam PF00106 short chain dehydrogenase 8 204 1.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06175 735ecd5d39948f823de8cc86e8ca48ef 71 Pfam PF00364 Biotin-requiring enzyme 10 70 3.4E-15 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS06175 735ecd5d39948f823de8cc86e8ca48ef 71 Gene3D G3DSA:2.40.50.100 1 71 6.1E-15 T 29-03-2018 MSG_RS06175 735ecd5d39948f823de8cc86e8ca48ef 71 SUPERFAMILY SSF51230 5 70 1.19E-17 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 SUPERFAMILY SSF47203 285 438 1.93E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 Gene3D G3DSA:1.20.140.10 269 441 1.5E-32 T 29-03-2018 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 436 5.1E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 SUPERFAMILY SSF56645 56 289 5.1E-35 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 269 1.2E-13 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 395 414 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MSG_RS04245 23be02aa47715f6a4c2983975723ac78 542 Gene3D G3DSA:2.40.110.10 166 268 1.9E-21 T 29-03-2018 MSG_RS06335 313d451fbacee7e9de74a0cd7cc4a303 340 SUPERFAMILY SSF54211 232 328 9.86E-19 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS06335 313d451fbacee7e9de74a0cd7cc4a303 340 SUPERFAMILY SSF50156 136 237 1.45E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS06335 313d451fbacee7e9de74a0cd7cc4a303 340 Pfam PF13180 PDZ domain 135 194 1.6E-10 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS06335 313d451fbacee7e9de74a0cd7cc4a303 340 Gene3D G3DSA:3.30.230.10 40 338 3.1E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS06335 313d451fbacee7e9de74a0cd7cc4a303 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 236 305 1.3E-8 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 Gene3D G3DSA:1.10.10.10 114 204 2.3E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 36 197 1.1E-30 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 SUPERFAMILY SSF46785 32 110 1.74E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 Gene3D G3DSA:1.10.10.10 24 113 7.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 SUPERFAMILY SSF46785 115 187 1.95E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 Pfam PF04079 Segregation and condensation complex subunit ScpB 39 195 2.6E-48 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MSG_RS11755 2cccd02ee4ef1488fd7b4f7b2734f5e0 239 PIRSF PIRSF019345 21 235 3.5E-60 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MSG_RS24520 d2ef1167c49d1fe77bf5073c2e39fa22 488 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 1 485 1.2E-121 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS24520 d2ef1167c49d1fe77bf5073c2e39fa22 488 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 1 83 1.4E-14 T 29-03-2018 IPR024962 YukD-like MSG_RS24520 d2ef1167c49d1fe77bf5073c2e39fa22 488 PIRSF PIRSF017804 1 488 2.2E-155 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS19850 d1eb21d1b89938e2082f25f94c5c2311 243 SUPERFAMILY SSF53955 70 241 3.37E-33 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS19850 d1eb21d1b89938e2082f25f94c5c2311 243 Pfam PF13406 Transglycosylase SLT domain 160 201 5.0E-7 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 MSG_RS19850 d1eb21d1b89938e2082f25f94c5c2311 243 Gene3D G3DSA:1.10.530.10 66 242 2.7E-26 T 29-03-2018 MSG_RS06235 ba87e566f457bfef5172d4ffacd797ea 242 Pfam PF05423 Mycobacterium membrane protein 148 237 3.4E-6 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 Gene3D G3DSA:3.50.50.60 246 331 3.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 Gene3D G3DSA:3.50.50.60 134 245 7.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 45 60 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 201 217 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 134 146 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 6.8E-79 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 141 161 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 12 311 1.2E-125 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 SUPERFAMILY SSF51905 7 311 1.3E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 300 2.3E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 Gene3D G3DSA:3.50.50.60 3 133 4.4E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 2.4E-36 T 29-03-2018 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 2.4E-36 T 29-03-2018 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.4E-36 T 29-03-2018 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 2.4E-36 T 29-03-2018 MSG_RS24660 62bff575bc23e83b1dec7649e0dee819 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.4E-36 T 29-03-2018 MSG_RS01900 34999866a5b09f7c3314b64747e86145 171 Gene3D G3DSA:1.10.260.40 95 157 1.3E-6 T 29-03-2018 MSG_RS01900 34999866a5b09f7c3314b64747e86145 171 SUPERFAMILY SSF47413 100 152 2.84E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS09225 c759c4c052be9acfd3c99c46b7ace7f0 122 Pfam PF05305 Protein of unknown function (DUF732) 6 109 4.8E-24 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS08065 09441384eee4bd2dcfaac88f63d9dfd6 245 Gene3D G3DSA:1.20.5.620 156 206 3.8E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS08065 09441384eee4bd2dcfaac88f63d9dfd6 245 Gene3D G3DSA:1.20.5.620 60 89 2.0E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS08065 09441384eee4bd2dcfaac88f63d9dfd6 245 Gene3D G3DSA:1.20.5.620 90 155 7.6E-10 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MSG_RS07645 83005d7fbb54b3852a68764d13286207 253 SMART SM00563 70 178 8.9E-25 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS07645 83005d7fbb54b3852a68764d13286207 253 SUPERFAMILY SSF69593 10 182 7.72E-18 T 29-03-2018 MSG_RS07645 83005d7fbb54b3852a68764d13286207 253 Gene3D G3DSA:3.40.1130.10 37 214 7.6E-17 T 29-03-2018 MSG_RS07645 83005d7fbb54b3852a68764d13286207 253 Pfam PF01553 Acyltransferase 57 174 1.2E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS20625 3ca00173f96118da9f3d635439d7fbbc 527 Gene3D G3DSA:3.40.710.10 51 406 3.3E-69 T 29-03-2018 MSG_RS20625 3ca00173f96118da9f3d635439d7fbbc 527 Pfam PF00144 Beta-lactamase 59 387 1.3E-60 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS20625 3ca00173f96118da9f3d635439d7fbbc 527 SUPERFAMILY SSF56601 52 401 2.44E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS20625 3ca00173f96118da9f3d635439d7fbbc 527 Pfam PF11954 Domain of unknown function (DUF3471) 434 499 2.5E-9 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 SMART SM01374 1 122 3.1E-86 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 4.6E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 Gene3D G3DSA:2.40.150.20 1 122 7.8E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.3E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 SUPERFAMILY SSF50193 2 122 7.72E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MSG_RS04555 842cb09940db4cc453ca06f4fb7503d8 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.794 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 8.7E-16 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.3E-9 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Gene3D G3DSA:2.40.110.10 160 274 1.5E-24 T 29-03-2018 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 148 3.1E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Gene3D G3DSA:1.10.540.10 28 156 2.4E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Gene3D G3DSA:1.20.140.10 275 476 3.4E-35 T 29-03-2018 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 475 604 3.6E-33 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 SUPERFAMILY SSF56645 36 295 3.93E-43 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 SUPERFAMILY SSF47203 292 469 1.08E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS10605 bfc01d51d4fe6d7389703da688a7c474 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 456 3.0E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS05595 339fb5911408dfb78a3b7c7c665b35b0 268 Gene3D G3DSA:3.30.2350.10 65 264 3.8E-48 T 29-03-2018 MSG_RS05595 339fb5911408dfb78a3b7c7c665b35b0 268 Pfam PF00849 RNA pseudouridylate synthase 73 216 4.6E-21 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS05595 339fb5911408dfb78a3b7c7c665b35b0 268 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 112 126 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS05595 339fb5911408dfb78a3b7c7c665b35b0 268 SUPERFAMILY SSF55120 59 264 2.56E-49 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS21160 962feccd3db535939df00947d987715b 332 Gene3D G3DSA:1.10.540.10 1 102 3.7E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS21160 962feccd3db535939df00947d987715b 332 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 194 325 2.4E-24 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21160 962feccd3db535939df00947d987715b 332 Gene3D G3DSA:1.20.140.10 184 310 1.0E-29 T 29-03-2018 MSG_RS21160 962feccd3db535939df00947d987715b 332 SUPERFAMILY SSF47203 190 326 4.03E-32 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS21160 962feccd3db535939df00947d987715b 332 SUPERFAMILY SSF56645 1 179 1.41E-13 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS12025 29d7f8a5659dc4bfdf90a96ab03c6ad2 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 269 3.4E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS12025 29d7f8a5659dc4bfdf90a96ab03c6ad2 272 Gene3D G3DSA:1.10.3720.10 8 270 7.5E-37 T 29-03-2018 MSG_RS12025 29d7f8a5659dc4bfdf90a96ab03c6ad2 272 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 8 262 1.7E-101 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MSG_RS12025 29d7f8a5659dc4bfdf90a96ab03c6ad2 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 261 2.9E-98 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MSG_RS12025 29d7f8a5659dc4bfdf90a96ab03c6ad2 272 SUPERFAMILY SSF161098 16 256 4.67E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS24685 77aa49ff249ba6974e19768bf63e34f5 299 SUPERFAMILY SSF52540 46 297 5.94E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS24685 77aa49ff249ba6974e19768bf63e34f5 299 Gene3D G3DSA:3.40.50.300 45 298 3.4E-61 T 29-03-2018 MSG_RS24685 77aa49ff249ba6974e19768bf63e34f5 299 Pfam PF13614 AAA domain 46 224 4.7E-58 T 29-03-2018 IPR025669 AAA domain MSG_RS07900 35d0f9c462895d0d385442cd9123906b 236 Pfam PF07510 Protein of unknown function (DUF1524) 89 211 1.6E-10 T 29-03-2018 IPR011089 Domain of unknown function DUF1524 MSG_RS07200 43caca67afed1481cc763970fd99f63e 236 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 185 195 - T 29-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 MSG_RS07200 43caca67afed1481cc763970fd99f63e 236 Gene3D G3DSA:3.90.70.10 57 236 4.9E-11 T 29-03-2018 MSG_RS07200 43caca67afed1481cc763970fd99f63e 236 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 38 236 6.0E-67 T 29-03-2018 MSG_RS01230 3fbaf947356ba822a907f26f46fb07fa 147 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 3 146 9.2E-65 T 29-03-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable MSG_RS01230 3fbaf947356ba822a907f26f46fb07fa 147 SUPERFAMILY SSF50475 7 146 3.55E-23 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS01230 3fbaf947356ba822a907f26f46fb07fa 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 108 7.2E-17 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS01230 3fbaf947356ba822a907f26f46fb07fa 147 Gene3D G3DSA:2.30.110.10 6 147 3.2E-26 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS10425 a201b9f15c042964d1a0aa2e7289ad44 418 SUPERFAMILY SSF53474 137 393 5.27E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10425 a201b9f15c042964d1a0aa2e7289ad44 418 Gene3D G3DSA:3.40.50.1820 105 414 1.7E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS10425 a201b9f15c042964d1a0aa2e7289ad44 418 Pfam PF07859 alpha/beta hydrolase fold 179 387 3.4E-18 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS16920 b92d37e949d2872e709f30724ec07110 200 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 95 194 9.1E-8 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MSG_RS16920 b92d37e949d2872e709f30724ec07110 200 SUPERFAMILY SSF50118 93 195 4.14E-8 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MSG_RS16920 b92d37e949d2872e709f30724ec07110 200 Gene3D G3DSA:2.30.30.110 92 197 2.7E-16 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MSG_RS14355 172b008d5da8dfc3efaa2904bdedd497 439 SUPERFAMILY SSF54909 82 431 6.44E-82 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS14355 172b008d5da8dfc3efaa2904bdedd497 439 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 83 427 5.4E-75 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MSG_RS14355 172b008d5da8dfc3efaa2904bdedd497 439 Pfam PF04261 Dyp-type peroxidase family 83 427 4.7E-89 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MSG_RS14355 172b008d5da8dfc3efaa2904bdedd497 439 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 21 438 1.1E-130 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 MSG_RS14585 d853cb53f51d3d5106f058a6337dd3cc 1195 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 7 1190 0.0 T 29-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 MSG_RS14585 d853cb53f51d3d5106f058a6337dd3cc 1195 Pfam PF02514 CobN/Magnesium Chelatase 108 1177 0.0 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 PRINTS PR00412 Epoxide hydrolase signature 50 68 2.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 PRINTS PR00412 Epoxide hydrolase signature 274 296 2.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 PRINTS PR00412 Epoxide hydrolase signature 114 127 2.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 Gene3D G3DSA:3.40.50.1820 23 296 5.5E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 SUPERFAMILY SSF53474 29 295 6.04E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00650 25e580a18a5c9e3729a849917e70c629 297 Pfam PF12697 Alpha/beta hydrolase family 46 292 2.7E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS17580 461080d8587e3ae9a9822b2928006282 155 Pfam PF04075 F420H(2)-dependent quinone reductase 13 143 2.6E-44 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS17580 461080d8587e3ae9a9822b2928006282 155 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 29 142 4.3E-35 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS17580 461080d8587e3ae9a9822b2928006282 155 Gene3D G3DSA:2.30.110.10 5 145 6.8E-34 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS21400 3728d6ae4943dd8baca64968fcc35948 391 Gene3D G3DSA:3.20.20.140 34 391 1.9E-49 T 29-03-2018 MSG_RS21400 3728d6ae4943dd8baca64968fcc35948 391 SUPERFAMILY SSF51556 106 390 2.98E-54 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21400 3728d6ae4943dd8baca64968fcc35948 391 SUPERFAMILY SSF51556 39 75 2.98E-54 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21400 3728d6ae4943dd8baca64968fcc35948 391 Pfam PF04909 Amidohydrolase 138 390 2.5E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 SUPERFAMILY SSF50331 240 354 5.78E-11 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 SMART SM00382 31 214 9.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 Pfam PF08402 TOBE domain 276 355 6.1E-11 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 Pfam PF00005 ABC transporter 23 165 2.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 SUPERFAMILY SSF52540 7 246 1.39E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS10105 6b28a46eee46060149b8471e68e6dd6a 355 Gene3D G3DSA:3.40.50.300 2 246 3.1E-71 T 29-03-2018 MSG_RS09030 6ad3d400cee8565eba9f648c78592a9b 125 SUPERFAMILY SSF55298 6 121 6.13E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS09030 6ad3d400cee8565eba9f648c78592a9b 125 Pfam PF01042 Endoribonuclease L-PSP 13 120 1.2E-24 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MSG_RS09030 6ad3d400cee8565eba9f648c78592a9b 125 Gene3D G3DSA:3.30.1330.40 2 121 2.4E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS16695 25e0262014101be2fdffe1d7dcdaa3a4 194 Gene3D G3DSA:1.20.120.520 3 177 1.4E-17 T 29-03-2018 MSG_RS16695 25e0262014101be2fdffe1d7dcdaa3a4 194 Pfam PF01814 Hemerythrin HHE cation binding domain 3 124 6.5E-12 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 Pfam PF00582 Universal stress protein family 2 132 6.0E-16 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 SUPERFAMILY SSF52402 1 141 1.0E-19 T 29-03-2018 MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 PRINTS PR01438 Universal stress protein signature 110 132 1.7E-10 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 PRINTS PR01438 Universal stress protein signature 1 18 1.7E-10 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 PRINTS PR01438 Universal stress protein signature 92 104 1.7E-10 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 SUPERFAMILY SSF52402 145 264 5.27E-6 T 29-03-2018 MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 Gene3D G3DSA:3.40.50.620 1 132 9.8E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS14060 836b1f6871cb814f6524229b84e85cee 266 Gene3D G3DSA:3.40.50.620 133 263 1.6E-7 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS08775 37cc9c3630cf046b2c1868bd577e5afd 228 Gene3D G3DSA:1.20.1170.10 18 226 5.1E-4 T 29-03-2018 MSG_RS08775 37cc9c3630cf046b2c1868bd577e5afd 228 Pfam PF05103 DivIVA protein 9 120 3.6E-6 T 29-03-2018 IPR007793 DivIVA family MSG_RS20275 2df7613b1ade40fbed7544139aba16a2 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 270 8.2E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS20275 2df7613b1ade40fbed7544139aba16a2 275 Gene3D G3DSA:3.90.226.10 2 274 8.3E-69 T 29-03-2018 MSG_RS20275 2df7613b1ade40fbed7544139aba16a2 275 SUPERFAMILY SSF52096 3 271 4.69E-65 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 Gene3D G3DSA:3.50.50.60 2 180 5.5E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 SUPERFAMILY SSF51905 73 239 5.18E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 SUPERFAMILY SSF51905 4 38 5.18E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 Gene3D G3DSA:3.50.50.60 194 413 1.2E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 SUPERFAMILY SSF51735 196 233 5.51E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 SUPERFAMILY SSF51735 271 336 5.51E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS16765 ab774d95c572e03d3ac30b67174d412f 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 87 283 2.4E-11 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase MSG_RS21760 e6de7fd4674b943dbe6cd91453df08d2 62 Pfam PF11273 Protein of unknown function (DUF3073) 2 59 1.2E-22 T 29-03-2018 IPR021426 Protein of unknown function DUF3073 MSG_RS18190 e26ad8f1ad582c0e80d87a313d72c11c 302 SUPERFAMILY SSF54637 24 130 1.6E-28 T 29-03-2018 IPR029069 HotDog domain MSG_RS18190 e26ad8f1ad582c0e80d87a313d72c11c 302 Gene3D G3DSA:3.10.129.10 150 298 2.3E-31 T 29-03-2018 MSG_RS18190 e26ad8f1ad582c0e80d87a313d72c11c 302 Gene3D G3DSA:3.10.129.10 23 136 1.4E-30 T 29-03-2018 MSG_RS18190 e26ad8f1ad582c0e80d87a313d72c11c 302 SUPERFAMILY SSF54637 137 297 1.74E-34 T 29-03-2018 IPR029069 HotDog domain MSG_RS18190 e26ad8f1ad582c0e80d87a313d72c11c 302 Pfam PF13622 Thioesterase-like superfamily 57 297 3.5E-41 T 29-03-2018 MSG_RS00530 d60151484833fc0c936ae88ac441f196 407 Gene3D G3DSA:1.20.1250.20 204 405 2.6E-18 T 29-03-2018 MSG_RS00530 d60151484833fc0c936ae88ac441f196 407 Pfam PF07690 Major Facilitator Superfamily 26 244 1.2E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS00530 d60151484833fc0c936ae88ac441f196 407 Pfam PF07690 Major Facilitator Superfamily 252 403 9.2E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS00530 d60151484833fc0c936ae88ac441f196 407 Gene3D G3DSA:1.20.1250.20 15 203 1.0E-26 T 29-03-2018 MSG_RS00530 d60151484833fc0c936ae88ac441f196 407 SUPERFAMILY SSF103473 14 400 7.85E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS23750 f15cbe12180cfe994e7c79fab07b3552 423 Pfam PF13469 Sulfotransferase family 121 370 1.0E-37 T 29-03-2018 MSG_RS23750 f15cbe12180cfe994e7c79fab07b3552 423 Gene3D G3DSA:3.40.50.300 118 400 1.4E-24 T 29-03-2018 MSG_RS23750 f15cbe12180cfe994e7c79fab07b3552 423 SUPERFAMILY SSF52540 117 156 6.54E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS23750 f15cbe12180cfe994e7c79fab07b3552 423 SUPERFAMILY SSF52540 254 405 6.54E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 SUPERFAMILY SSF53720 27 436 6.28E-71 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.309 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 Gene3D G3DSA:3.40.50.1980 234 380 4.1E-59 T 29-03-2018 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PIRSF PIRSF000099 2 438 1.4E-148 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 2.1E-139 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 Pfam PF00815 Histidinol dehydrogenase 23 436 1.0E-154 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 3.7E-86 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MSG_RS11155 ee3536bcf89b6150a68cc0d5d3ee603e 438 Gene3D G3DSA:3.40.50.1980 28 233 4.7E-82 T 29-03-2018 MSG_RS15835 5d24ae817ccaf143f3099ff3beb98cfc 114 Pfam PF05423 Mycobacterium membrane protein 32 112 2.4E-8 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 SUPERFAMILY SSF51717 6 270 4.45E-91 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 Pfam PF00809 Pterin binding enzyme 9 255 2.6E-85 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 7 269 9.1E-94 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 8 23 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 42 55 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MSG_RS22855 2d159c85a49ad9c885f70fd45422a8a0 280 Gene3D G3DSA:3.20.20.20 2 277 1.8E-102 T 29-03-2018 MSG_RS18745 b635ee419b33fcb0cde745297a9438a3 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 271 9.2E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18745 b635ee419b33fcb0cde745297a9438a3 279 SUPERFAMILY SSF161098 9 279 1.21E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18745 b635ee419b33fcb0cde745297a9438a3 279 Gene3D G3DSA:1.10.3720.10 3 266 4.5E-42 T 29-03-2018 MSG_RS12715 d1609f9aeb663000655e4c00267f226a 403 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 310 399 2.1E-17 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12715 d1609f9aeb663000655e4c00267f226a 403 Gene3D G3DSA:1.10.287.1060 22 106 3.5E-7 T 29-03-2018 MSG_RS12715 d1609f9aeb663000655e4c00267f226a 403 SUPERFAMILY SSF140459 4 173 1.15E-60 T 29-03-2018 MSG_RS12715 d1609f9aeb663000655e4c00267f226a 403 Pfam PF00823 PPE family 7 162 7.0E-61 T 29-03-2018 IPR000030 PPE family MSG_RS06130 e14cb665c54542b16b1c06d67b7d207f 392 Gene3D G3DSA:1.10.10.10 251 373 1.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06130 e14cb665c54542b16b1c06d67b7d207f 392 Pfam PF13556 PucR C-terminal helix-turn-helix domain 324 380 7.0E-12 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 SUPERFAMILY SSF51735 9 244 2.9E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 Gene3D G3DSA:3.40.50.720 4 264 2.0E-49 T 29-03-2018 MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 Pfam PF00106 short chain dehydrogenase 12 198 2.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS17490 146582d05826b70c46aab1fe9575719c 268 PIRSF PIRSF000126 4 266 5.6E-67 T 29-03-2018 MSG_RS20610 8fde577b8cebc8cc9918613542e7b168 157 Gene3D G3DSA:3.30.530.20 2 146 1.9E-12 T 29-03-2018 IPR023393 START-like domain MSG_RS20610 8fde577b8cebc8cc9918613542e7b168 157 SUPERFAMILY SSF55961 1 141 2.42E-18 T 29-03-2018 MSG_RS20610 8fde577b8cebc8cc9918613542e7b168 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 141 4.4E-19 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS16430 ab5721e2a6c41384e8e41c346e73c831 295 SUPERFAMILY SSF55909 28 293 8.05E-58 T 29-03-2018 MSG_RS16430 ab5721e2a6c41384e8e41c346e73c831 295 Gene3D G3DSA:3.75.10.10 26 294 1.1E-57 T 29-03-2018 MSG_RS16430 ab5721e2a6c41384e8e41c346e73c831 295 Pfam PF02274 Amidinotransferase 90 295 3.1E-14 T 29-03-2018 MSG_RS03695 a9468933cdee30f1a5ab04458bf12882 526 Pfam PF05140 ResB-like family 1 498 2.7E-131 T 29-03-2018 IPR007816 ResB-like domain MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 Pfam PF02515 CoA-transferase family III 8 357 6.9E-55 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 Pfam PF02515 CoA-transferase family III 379 747 2.0E-93 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 SUPERFAMILY SSF89796 376 772 1.57E-94 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 SUPERFAMILY SSF89796 5 361 5.76E-61 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 Gene3D G3DSA:3.40.50.10540 374 777 1.6E-101 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS00840 10f5411d2a3fd12779b7e533777d6a21 779 Gene3D G3DSA:3.40.50.10540 1 362 7.2E-64 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.6E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.6E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 SUPERFAMILY SSF55811 3 126 2.98E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 Gene3D G3DSA:3.90.79.10 4 130 4.1E-22 T 29-03-2018 MSG_RS19120 ac35e8f187996047a7385dacd9fbe2c8 130 Pfam PF00293 NUDIX domain 6 123 4.6E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS00200 967e56b38e5a5d3807979cc4283306e5 472 Pfam PF10774 Domain of unknown function (DUF4226) 76 185 8.1E-34 T 29-03-2018 IPR019710 Protein of unknown function DUF4226 MSG_RS13125 b02154767715308755a6796dd0d48609 320 Pfam PF03466 LysR substrate binding domain 94 300 6.0E-44 T 29-03-2018 IPR005119 LysR, substrate-binding MSG_RS13125 b02154767715308755a6796dd0d48609 320 Gene3D G3DSA:3.40.190.10 95 182 4.7E-23 T 29-03-2018 MSG_RS13125 b02154767715308755a6796dd0d48609 320 Gene3D G3DSA:3.40.190.10 183 272 9.6E-25 T 29-03-2018 MSG_RS13125 b02154767715308755a6796dd0d48609 320 SUPERFAMILY SSF46785 4 117 3.15E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS13125 b02154767715308755a6796dd0d48609 320 SUPERFAMILY SSF53850 94 303 1.02E-39 T 29-03-2018 MSG_RS13125 b02154767715308755a6796dd0d48609 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 2.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MSG_RS13125 b02154767715308755a6796dd0d48609 320 Gene3D G3DSA:1.10.10.10 5 90 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23655 9968dc2dd910894aec971b4d8e69ecfe 161 SUPERFAMILY SSF55811 2 149 1.35E-18 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS23655 9968dc2dd910894aec971b4d8e69ecfe 161 Gene3D G3DSA:3.90.79.10 1 152 3.3E-23 T 29-03-2018 MSG_RS23655 9968dc2dd910894aec971b4d8e69ecfe 161 Pfam PF00293 NUDIX domain 2 147 7.3E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 Pfam PF13365 Trypsin-like peptidase domain 68 210 2.6E-25 T 29-03-2018 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 Gene3D G3DSA:2.30.42.10 245 337 8.3E-14 T 29-03-2018 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 SMART SM00228 255 326 1.8E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 Pfam PF13180 PDZ domain 257 333 2.2E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 203 220 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 181 198 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 77 89 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 284 296 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 138 162 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 PRINTS PR00834 HtrA/DegQ protease family signature 99 119 1.0E-23 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 Gene3D G3DSA:2.40.10.10 43 140 3.2E-20 T 29-03-2018 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 SUPERFAMILY SSF50494 48 237 1.4E-38 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 Gene3D G3DSA:2.40.10.10 141 238 8.7E-22 T 29-03-2018 MSG_RS01235 eb7480570d22cbce4d4f3fce2f2cfea3 341 SUPERFAMILY SSF50156 266 339 4.47E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MSG_RS14840 1b91dae4e835b31ec619ed13650cb0b0 351 Pfam PF02470 MlaD protein 39 111 2.7E-16 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS14840 1b91dae4e835b31ec619ed13650cb0b0 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 281 1.5E-56 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS24215 aadeb2a7d74d930b56c3ddaa40766d73 297 Pfam PF01744 GLTT repeat (6 copies) 75 101 3.1E-6 T 29-03-2018 IPR008164 Repeat of unknown function XGLTT MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 SUPERFAMILY SSF51735 13 257 9.71E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 Gene3D G3DSA:3.40.50.720 9 279 3.2E-69 T 29-03-2018 MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.4E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.2E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12250 505016cd8766107c2877745cc80fb5ba 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 256 3.0E-62 T 29-03-2018 MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 5.7E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 223 5.7E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 5.7E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 242 5.7E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 194 5.7E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 SUPERFAMILY SSF51735 53 284 4.08E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 204 223 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 184 192 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 Gene3D G3DSA:3.40.50.720 48 332 2.8E-56 T 29-03-2018 MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 Pfam PF00106 short chain dehydrogenase 54 243 4.4E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10980 2984f89891e86607a6ec6f873323d69d 338 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 54 239 0.0061 T 29-03-2018 MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.3E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 Gene3D G3DSA:3.40.50.720 1 249 7.2E-46 T 29-03-2018 MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 SUPERFAMILY SSF51735 3 245 1.08E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 Pfam PF00106 short chain dehydrogenase 5 198 6.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20395 83e26f13eb44fb1621bed9673e90846a 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS10720 451f39b74fcd19b3bb60dda7759ff20f 253 Pfam PF09335 SNARE associated Golgi protein 84 200 6.8E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 SUPERFAMILY SSF46689 7 67 1.94E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 Gene3D G3DSA:1.10.10.60 2 58 1.0E-17 T 29-03-2018 MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 Gene3D G3DSA:1.10.357.10 59 214 3.9E-12 T 29-03-2018 MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS04380 96d70ec2c7a54109a0d0a60db11da3ae 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS09870 9c01483d2a73f63e89bda541943270d1 207 Gene3D G3DSA:3.30.70.100 101 204 6.1E-5 T 29-03-2018 MSG_RS09870 9c01483d2a73f63e89bda541943270d1 207 Gene3D G3DSA:3.30.70.100 3 100 0.01 T 29-03-2018 MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 SUPERFAMILY SSF51735 6 277 2.99E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 1.1E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 Gene3D G3DSA:3.40.50.720 1 279 1.7E-66 T 29-03-2018 MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 275 5.5E-53 T 29-03-2018 MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 5 278 1.6E-117 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 260 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS21365 aed03e234d43361347dff5440a5c5f4e 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 4.2E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 167 180 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 382 396 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 299 319 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 221 236 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 243 271 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PRINTS PR00143 Citrate synthase signature 362 378 1.9E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 SUPERFAMILY SSF48256 7 431 1.96E-160 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 Pfam PF00285 Citrate synthase, C-terminal domain 48 414 4.0E-138 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 425 4.4E-182 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 PIRSF PIRSF001369 39 431 4.9E-158 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 Gene3D G3DSA:1.10.230.10 285 382 1.4E-35 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain MSG_RS20690 6841f837969a1c99734bbda65deac5e0 431 Gene3D G3DSA:1.10.580.10 33 284 3.2E-93 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 Pfam PF00890 FAD binding domain 12 536 7.9E-109 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 Gene3D G3DSA:3.50.50.60 10 344 2.7E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 Gene3D G3DSA:3.50.50.60 348 552 1.0E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 PIRSF PIRSF036654 6 554 6.5E-304 T 29-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 SUPERFAMILY SSF51905 11 282 1.01E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21925 5a89b2eb83a1acf4b6ec6cc221848bee 555 SUPERFAMILY SSF51905 491 553 1.01E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 Hamap MF_00384 Homoserine kinase [thrB]. 8 303 27.646 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 Gene3D G3DSA:3.30.230.10 8 171 1.2E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PIRSF PIRSF000676 5 295 6.7E-78 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 Gene3D G3DSA:3.30.70.890 172 294 1.2E-18 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 Pfam PF00288 GHMP kinases N terminal domain 85 149 9.7E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 SUPERFAMILY SSF55060 176 276 2.11E-21 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 91 102 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 TIGRFAM TIGR00191 thrB: homoserine kinase 12 278 2.7E-58 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 SUPERFAMILY SSF54211 11 154 4.25E-26 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PRINTS PR00958 Homoserine kinase signature 15 30 1.3E-36 T 29-03-2018 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PRINTS PR00958 Homoserine kinase signature 98 113 1.3E-36 T 29-03-2018 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PRINTS PR00958 Homoserine kinase signature 256 271 1.3E-36 T 29-03-2018 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PRINTS PR00958 Homoserine kinase signature 136 149 1.3E-36 T 29-03-2018 MSG_RS18320 6589af782ec7305351d65d2031effa7b 311 PRINTS PR00958 Homoserine kinase signature 179 196 1.3E-36 T 29-03-2018 MSG_RS06350 b574746369767682d15a66502a091ae1 217 Gene3D G3DSA:1.10.3210.10 17 206 3.3E-10 T 29-03-2018 MSG_RS06350 b574746369767682d15a66502a091ae1 217 Pfam PF01966 HD domain 37 121 1.7E-6 T 29-03-2018 IPR006674 HD domain MSG_RS06350 b574746369767682d15a66502a091ae1 217 SUPERFAMILY SSF109604 27 136 1.4E-12 T 29-03-2018 MSG_RS01780 c29f43bae952c7067043a3736cee9d21 365 Pfam PF09992 Phosphodiester glycosidase 146 341 5.9E-8 T 29-03-2018 IPR018711 Phosphodiester glycosidase MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 8 217 3.8E-59 T 29-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 SUPERFAMILY SSF56784 7 245 3.25E-38 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 136 216 5.9E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 212 5.6E-16 T 29-03-2018 IPR023214 HAD-like domain MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 Gene3D G3DSA:1.10.150.240 21 105 3.1E-24 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MSG_RS05145 ebfb3b72da21c4855dc0e754fe590c1e 252 Gene3D G3DSA:3.40.50.1000 106 250 1.1E-21 T 29-03-2018 IPR023214 HAD-like domain MSG_RS04250 2bbc8d52bad69994e10fd9eb5e3b02c8 312 SUPERFAMILY SSF52096 10 279 2.99E-52 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04250 2bbc8d52bad69994e10fd9eb5e3b02c8 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 83 1.5E-10 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS04250 2bbc8d52bad69994e10fd9eb5e3b02c8 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 124 272 7.7E-20 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS04250 2bbc8d52bad69994e10fd9eb5e3b02c8 312 Gene3D G3DSA:3.90.226.10 8 312 8.5E-59 T 29-03-2018 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-21 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.0E-21 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.0E-21 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 30.805 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 Pfam PF01197 Ribosomal protein L31 1 66 2.2E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.3E-32 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS18305 8da9966d126899c6fcb5e3f1b2c058fa 78 SUPERFAMILY SSF143800 1 66 4.32E-26 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 ProSitePatterns PS00893 Nudix box signature. 197 218 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 44 128 1.9E-5 T 29-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 Gene3D G3DSA:3.90.79.10 163 307 1.0E-33 T 29-03-2018 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 SUPERFAMILY SSF55811 117 280 4.6E-40 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 131 161 5.6E-6 T 29-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MSG_RS06290 a06181a60ee064d146bcb6970185aa18 307 Pfam PF00293 NUDIX domain 166 277 1.6E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS23850 ffe59bf2d453e38c6983c1f256cf5684 217 SUPERFAMILY SSF53335 8 182 3.68E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23850 ffe59bf2d453e38c6983c1f256cf5684 217 Gene3D G3DSA:3.40.50.150 1 202 3.8E-23 T 29-03-2018 MSG_RS23850 ffe59bf2d453e38c6983c1f256cf5684 217 Pfam PF13649 Methyltransferase domain 40 138 5.1E-15 T 29-03-2018 MSG_RS20795 b2f8a8def77e8a57a1abfc628f55d009 92 Gene3D G3DSA:3.10.20.30 13 92 3.6E-23 T 29-03-2018 IPR012675 Beta-grasp domain MSG_RS20795 b2f8a8def77e8a57a1abfc628f55d009 92 SUPERFAMILY SSF54285 13 90 1.21E-13 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MSG_RS20795 b2f8a8def77e8a57a1abfc628f55d009 92 Pfam PF02597 ThiS family 15 92 1.4E-11 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MSG_RS17355 14783c7320f4494b2445ab797ddf5149 415 Gene3D G3DSA:3.40.50.1820 111 399 4.0E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17355 14783c7320f4494b2445ab797ddf5149 415 Pfam PF07859 alpha/beta hydrolase fold 167 373 2.1E-22 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS17355 14783c7320f4494b2445ab797ddf5149 415 SUPERFAMILY SSF53474 124 376 9.98E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01740 e2221ff45474588cff8dbafc49b745d8 530 Gene3D G3DSA:3.90.20.10 144 315 1.2E-5 T 29-03-2018 MSG_RS01740 e2221ff45474588cff8dbafc49b745d8 530 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 312 6.4E-91 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01740 e2221ff45474588cff8dbafc49b745d8 530 Pfam PF02470 MlaD protein 47 120 4.4E-12 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS11745 8de7552200e648be4b84203501f67ef6 287 Pfam PF13614 AAA domain 34 210 1.6E-60 T 29-03-2018 IPR025669 AAA domain MSG_RS11745 8de7552200e648be4b84203501f67ef6 287 SUPERFAMILY SSF52540 33 285 8.28E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11745 8de7552200e648be4b84203501f67ef6 287 Gene3D G3DSA:3.40.50.300 32 287 2.4E-61 T 29-03-2018 MSG_RS06430 2a09dc7cb8680a10cf8023ca99bca6bc 157 Pfam PF04138 GtrA-like protein 42 155 1.2E-12 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 MSG_RS01175 586b28a2c53e9c969fb0b8d8e0a9bb10 581 Pfam PF01566 Natural resistance-associated macrophage protein 72 425 3.6E-71 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MSG_RS14855 66a5ee5cc9ebd5c2ba828b6193cca1a4 419 Pfam PF02470 MlaD protein 45 119 3.0E-13 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS12580 b846e0a52ae14f4a9de919f811543854 96 Pfam PF03861 ANTAR domain 18 61 8.9E-7 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS12580 b846e0a52ae14f4a9de919f811543854 96 SMART SM01012 6 61 9.5E-6 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 MSG_RS12580 b846e0a52ae14f4a9de919f811543854 96 Gene3D G3DSA:1.10.10.10 16 62 1.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 PIRSF PIRSF018005 2 321 9.3E-135 T 29-03-2018 IPR017804 Methyltransferase EgtD-like MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 SUPERFAMILY SSF53335 37 219 8.08E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 19 320 9.8E-110 T 29-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 318 5.1E-111 T 29-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 Gene3D G3DSA:3.40.50.150 6 319 6.1E-19 T 29-03-2018 MSG_RS23340 725a732bb442bfd966c218d994a5a1df 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 5 321 54.332 T 29-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 MSG_RS10740 d8e1c5d64405f922e55957f0ffdb75d9 405 Pfam PF00144 Beta-lactamase 23 358 3.1E-62 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS10740 d8e1c5d64405f922e55957f0ffdb75d9 405 SUPERFAMILY SSF56601 251 358 2.41E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS10740 d8e1c5d64405f922e55957f0ffdb75d9 405 SUPERFAMILY SSF56601 9 215 2.41E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS10740 d8e1c5d64405f922e55957f0ffdb75d9 405 Gene3D G3DSA:3.40.710.10 9 364 6.5E-70 T 29-03-2018 MSG_RS04785 dc72f892a163f01e0dac14591aa85b06 162 Gene3D G3DSA:3.40.190.10 2 157 1.8E-5 T 29-03-2018 MSG_RS04785 dc72f892a163f01e0dac14591aa85b06 162 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 55 161 1.1E-27 T 29-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 MSG_RS01410 ce4d318c5cba15ab97fd3a209085b324 122 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 26 85 1.0E-7 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS01410 ce4d318c5cba15ab97fd3a209085b324 122 SUPERFAMILY SSF117916 14 82 2.83E-13 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS01410 ce4d318c5cba15ab97fd3a209085b324 122 Gene3D G3DSA:3.30.300.130 11 92 4.9E-15 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MSG_RS01410 ce4d318c5cba15ab97fd3a209085b324 122 Pfam PF01106 NifU-like domain 20 84 2.9E-12 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MSG_RS09770 0025836c017c93847c2869aa832a3600 528 Gene3D G3DSA:2.60.40.380 60 158 4.9E-14 T 29-03-2018 MSG_RS09770 0025836c017c93847c2869aa832a3600 528 Pfam PF00149 Calcineurin-like phosphoesterase 204 385 2.8E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MSG_RS09770 0025836c017c93847c2869aa832a3600 528 SUPERFAMILY SSF49363 50 147 2.35E-21 T 29-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 MSG_RS09770 0025836c017c93847c2869aa832a3600 528 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 63 144 1.9E-16 T 29-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 MSG_RS09770 0025836c017c93847c2869aa832a3600 528 SUPERFAMILY SSF56300 163 487 4.68E-44 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS09770 0025836c017c93847c2869aa832a3600 528 Gene3D G3DSA:3.60.21.10 159 526 9.0E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MSG_RS07335 f0d5c72f1f8cb6f065078f755a240f9f 185 Gene3D G3DSA:3.40.50.360 1 184 6.2E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS07335 f0d5c72f1f8cb6f065078f755a240f9f 185 SUPERFAMILY SSF52218 5 172 1.12E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain MSG_RS07335 f0d5c72f1f8cb6f065078f755a240f9f 185 Pfam PF03358 NADPH-dependent FMN reductase 5 154 1.0E-31 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 101 113 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 55 67 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 26 38 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 373 385 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 39 49 5.8E-29 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 378 388 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 506 3.6E-14 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 31 48 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 Pfam PF01266 FAD dependent oxidoreductase 27 354 2.3E-45 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 SUPERFAMILY SSF51905 27 353 3.89E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15760 48369441388421e3888f1d202c9c09b7 510 Gene3D G3DSA:3.50.50.60 5 420 1.4E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12730 a3b514ab9b82e2b5699cdd948434f3c6 466 Gene3D G3DSA:1.10.287.1060 20 105 9.7E-8 T 29-03-2018 MSG_RS12730 a3b514ab9b82e2b5699cdd948434f3c6 466 Gene3D G3DSA:1.10.357.10 183 443 0.0051 T 29-03-2018 MSG_RS12730 a3b514ab9b82e2b5699cdd948434f3c6 466 SUPERFAMILY SSF140459 3 173 2.25E-61 T 29-03-2018 MSG_RS12730 a3b514ab9b82e2b5699cdd948434f3c6 466 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 396 1.3E-11 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12730 a3b514ab9b82e2b5699cdd948434f3c6 466 Pfam PF00823 PPE family 5 161 4.1E-62 T 29-03-2018 IPR000030 PPE family MSG_RS05395 43309fc6acccef5f965d4ab8b9f95a3c 342 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 21 289 1.1E-91 T 29-03-2018 IPR005274 Inner membrane protein YhjD MSG_RS05395 43309fc6acccef5f965d4ab8b9f95a3c 342 PIRSF PIRSF035875 11 309 2.3E-22 T 29-03-2018 IPR017039 Virulence factor BrkB MSG_RS05395 43309fc6acccef5f965d4ab8b9f95a3c 342 Pfam PF03631 Virulence factor BrkB 36 289 8.7E-41 T 29-03-2018 IPR017039 Virulence factor BrkB MSG_RS12970 f389111a965c4abb7b356f77fc1d4b2a 214 Pfam PF01774 UreD urease accessory protein 33 160 9.2E-17 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 725 0.0 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Hamap MF_00641 Malate synthase G [glcB]. 1 728 404.052 T 29-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Pfam PF01274 Malate synthase 17 700 1.2E-195 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Gene3D G3DSA:1.20.1220.12 592 728 2.1E-43 T 29-03-2018 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Gene3D G3DSA:3.20.20.360 219 591 2.5E-102 T 29-03-2018 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Gene3D G3DSA:3.20.20.360 89 213 3.4E-26 T 29-03-2018 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 Gene3D G3DSA:1.10.1860.10 1 88 1.6E-36 T 29-03-2018 MSG_RS12905 17a0ec4d7bb50cee13146dcf1c388d0f 728 SUPERFAMILY SSF51645 2 725 9.16E-301 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MSG_RS14785 866442f0d586d20dd5f6161357047173 90 Pfam PF04456 Protein of unknown function (DUF503) 3 89 6.9E-30 T 29-03-2018 IPR007546 Protein of unknown function DUF503 MSG_RS14785 866442f0d586d20dd5f6161357047173 90 Gene3D G3DSA:3.30.70.1120 2 90 1.0E-31 T 29-03-2018 MSG_RS14785 866442f0d586d20dd5f6161357047173 90 SUPERFAMILY SSF103007 1 89 3.27E-28 T 29-03-2018 IPR007546 Protein of unknown function DUF503 MSG_RS03530 a72acf192d13d4ab3d249b0a5fe8339d 33 SMART SM01155 1 33 2.8E-8 T 29-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS03530 a72acf192d13d4ab3d249b0a5fe8339d 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 4.1E-12 T 29-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 5.7E-87 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 SUPERFAMILY SSF52540 1 220 8.65E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 Gene3D G3DSA:3.40.50.300 1 222 6.0E-64 T 29-03-2018 MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 SMART SM00382 28 215 1.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS06880 4989ec594a7445df1b8b6ba06cfad583 229 Pfam PF00005 ABC transporter 19 166 2.9E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18495 833b1684a24c67ccc7cb6102ddece4e8 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 1.6E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18495 833b1684a24c67ccc7cb6102ddece4e8 308 SUPERFAMILY SSF161098 95 282 9.16E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18495 833b1684a24c67ccc7cb6102ddece4e8 308 Gene3D G3DSA:1.10.3720.10 18 287 6.4E-35 T 29-03-2018 MSG_RS18495 833b1684a24c67ccc7cb6102ddece4e8 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 73 2.8E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 320 340 7.3E-5 T 29-03-2018 MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 64 84 7.3E-5 T 29-03-2018 MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 PRINTS PR01036 Tetracycline resistance protein TetB signature 94 118 7.3E-5 T 29-03-2018 MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 SUPERFAMILY SSF103473 1 153 8.11E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 SUPERFAMILY SSF103473 209 428 8.11E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 Pfam PF07690 Major Facilitator Superfamily 1 371 1.6E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 Gene3D G3DSA:1.20.1250.20 1 155 3.7E-30 T 29-03-2018 MSG_RS08285 791fb32724eaba863752f70a542cc77e 473 Gene3D G3DSA:1.20.1250.20 213 443 9.2E-20 T 29-03-2018 MSG_RS18285 4873542e34d81754eed8cb13b5fc8a69 395 Pfam PF00953 Glycosyl transferase family 4 100 264 2.0E-34 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MSG_RS21425 bf0a4b734f856dba24eecdcfce013499 249 Gene3D G3DSA:3.90.25.10 145 227 6.7E-5 T 29-03-2018 MSG_RS21425 bf0a4b734f856dba24eecdcfce013499 249 Gene3D G3DSA:3.40.50.720 1 144 1.2E-9 T 29-03-2018 MSG_RS21425 bf0a4b734f856dba24eecdcfce013499 249 SUPERFAMILY SSF51735 1 218 9.9E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS21425 bf0a4b734f856dba24eecdcfce013499 249 Pfam PF13460 NAD(P)H-binding 7 173 2.8E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS03155 b84285d0f5c2878ff035bcbed50f5e1a 340 Pfam PF00296 Luciferase-like monooxygenase 12 304 1.6E-47 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS03155 b84285d0f5c2878ff035bcbed50f5e1a 340 Gene3D G3DSA:3.20.20.30 1 340 2.0E-51 T 29-03-2018 MSG_RS03155 b84285d0f5c2878ff035bcbed50f5e1a 340 SUPERFAMILY SSF51679 7 322 2.71E-52 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS03155 b84285d0f5c2878ff035bcbed50f5e1a 340 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 18 334 1.1E-139 T 29-03-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 Gene3D G3DSA:3.40.50.720 1 260 1.3E-60 T 29-03-2018 MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 SUPERFAMILY SSF51735 6 257 1.27E-69 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 5.3E-53 T 29-03-2018 MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS22430 354fe7dafe988f4c40e2c5453d8fb0f3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 254 2.6E-43 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 Gene3D G3DSA:3.40.47.10 5 266 1.0E-55 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 374 2.1E-34 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 SUPERFAMILY SSF53901 12 259 3.29E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 SUPERFAMILY SSF53901 221 417 8.65E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 SMART SM00825 Beta-ketoacyl synthase 13 408 4.0E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MSG_RS05185 cbc3f103d07c38639e600217d65b8101 417 Gene3D G3DSA:3.40.47.10 270 417 4.3E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 58 535 1.5E-104 T 29-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 305 524 3.6E-53 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 PIRSF PIRSF001217 2 580 5.1E-162 T 29-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 SUPERFAMILY SSF52096 53 154 1.41E-21 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 SUPERFAMILY SSF52096 187 248 1.41E-21 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 Gene3D G3DSA:3.90.226.10 295 539 2.6E-47 T 29-03-2018 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 Pfam PF01343 Peptidase family S49 107 259 2.9E-41 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 Pfam PF01343 Peptidase family S49 375 526 2.6E-51 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 SUPERFAMILY SSF52096 452 512 4.57E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 SUPERFAMILY SSF52096 290 423 4.57E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS04610 d0512aeed4d7336222cd854dbb8517d7 594 Gene3D G3DSA:3.90.226.10 33 271 1.5E-19 T 29-03-2018 MSG_RS07025 6c3810c1a08284059fd7244af8f98c7d 678 Pfam PF11175 Protein of unknown function (DUF2961) 275 521 2.0E-52 T 29-03-2018 IPR021345 Protein of unknown function DUF2961 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 Pfam PF04679 ATP dependent DNA ligase C terminal region 216 328 2.8E-15 T 29-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 Gene3D G3DSA:3.30.470.30 2 136 1.7E-30 T 29-03-2018 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 Pfam PF01068 ATP dependent DNA ligase domain 11 197 1.7E-37 T 29-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 SUPERFAMILY SSF56091 6 196 2.64E-41 T 29-03-2018 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 Gene3D G3DSA:2.40.50.140 197 343 6.3E-31 T 29-03-2018 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 Gene3D G3DSA:3.30.1490.70 137 196 6.6E-9 T 29-03-2018 MSG_RS23640 ef4166e2ab097858a9fd0718a1b50096 354 SUPERFAMILY SSF50249 200 337 5.14E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS17870 d3d8ba4b66a90d513d2ba870d1b7f151 151 Gene3D G3DSA:3.10.450.50 1 147 6.2E-30 T 29-03-2018 MSG_RS17870 d3d8ba4b66a90d513d2ba870d1b7f151 151 Pfam PF13577 SnoaL-like domain 11 138 3.3E-24 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS17870 d3d8ba4b66a90d513d2ba870d1b7f151 151 SUPERFAMILY SSF54427 9 143 2.43E-31 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS11240 67799bc374219b66e41e4a4212d23aa4 680 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 143 155 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MSG_RS11240 67799bc374219b66e41e4a4212d23aa4 680 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 279 15.222 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MSG_RS11240 67799bc374219b66e41e4a4212d23aa4 680 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 15 273 2.6E-60 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MSG_RS11240 67799bc374219b66e41e4a4212d23aa4 680 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 14 273 4.4E-39 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MSG_RS18100 02299a06693759843d0c785d54265c2b 101 SUPERFAMILY SSF54736 25 98 5.75E-24 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MSG_RS18100 02299a06693759843d0c785d54265c2b 101 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 6 101 17.174 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MSG_RS18100 02299a06693759843d0c785d54265c2b 101 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 26 95 1.2E-21 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MSG_RS18100 02299a06693759843d0c785d54265c2b 101 Gene3D G3DSA:3.30.1390.10 26 97 3.6E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MSG_RS12110 4bfc5acf647087e625a034a74ab62ba2 261 Pfam PF13529 Peptidase_C39 like family 84 229 3.7E-6 T 29-03-2018 MSG_RS12110 4bfc5acf647087e625a034a74ab62ba2 261 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 72 257 3.0E-53 T 29-03-2018 MSG_RS12110 4bfc5acf647087e625a034a74ab62ba2 261 Gene3D G3DSA:3.90.70.10 85 261 1.5E-13 T 29-03-2018 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 Pfam PF01791 DeoC/LacD family aldolase 10 218 5.0E-14 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 Gene3D G3DSA:3.20.20.70 1 223 2.1E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 10 216 7.0E-60 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 SMART SM01133 9 222 5.4E-75 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 SUPERFAMILY SSF51569 6 222 3.77E-65 T 29-03-2018 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 8 224 31.492 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 MSG_RS03415 25a163d80c23e818429601d665e78a34 225 PIRSF PIRSF001357 3 223 3.4E-66 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MSG_RS17670 f90f584ab1802c256c95683742a6eabc 192 SUPERFAMILY SSF54637 30 189 2.35E-22 T 29-03-2018 IPR029069 HotDog domain MSG_RS17670 f90f584ab1802c256c95683742a6eabc 192 Gene3D G3DSA:3.10.129.10 27 192 3.7E-29 T 29-03-2018 MSG_RS17670 f90f584ab1802c256c95683742a6eabc 192 Pfam PF13452 N-terminal half of MaoC dehydratase 36 178 4.4E-18 T 29-03-2018 MSG_RS18535 187f884a123ad941c067c9b75fec43bb 180 Pfam PF12079 Protein of unknown function (DUF3558) 17 177 5.6E-29 T 29-03-2018 IPR024520 Protein of unknown function DUF3558 MSG_RS02435 625896cc709739f7de632ac18b9d2f01 256 SUPERFAMILY SSF55469 23 231 3.53E-49 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS02435 625896cc709739f7de632ac18b9d2f01 256 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 21 221 1.5E-74 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 MSG_RS02435 625896cc709739f7de632ac18b9d2f01 256 Gene3D G3DSA:3.40.109.10 19 233 3.3E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MSG_RS02435 625896cc709739f7de632ac18b9d2f01 256 Pfam PF00881 Nitroreductase family 33 197 5.0E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 Gene3D G3DSA:3.90.470.20 13 114 3.6E-13 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 SUPERFAMILY SSF56214 106 224 3.14E-15 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 PRINTS PR01399 Enterobactin synthetase component D signature 74 92 1.2E-27 T 29-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 PRINTS PR01399 Enterobactin synthetase component D signature 44 64 1.2E-27 T 29-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 PRINTS PR01399 Enterobactin synthetase component D signature 149 165 1.2E-27 T 29-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 108 185 1.6E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS08590 ac9bec6aafe6636452d6d13fa69424e6 225 Gene3D G3DSA:3.90.470.20 115 224 8.8E-9 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 Gene3D G3DSA:3.30.70.660 156 293 3.4E-33 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 PIRSF PIRSF001430 37 310 9.6E-73 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 40 289 1.3E-50 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 38 294 31.305 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 Gene3D G3DSA:3.30.70.580 35 155 3.4E-32 T 29-03-2018 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 SUPERFAMILY SSF55120 38 303 1.09E-74 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS04855 37e7c22c03caba564cee6050a6a9158b 314 Pfam PF01416 tRNA pseudouridine synthase 194 295 1.1E-25 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MSG_RS15515 acac5feabad9906cce0f7b0e856df301 463 SUPERFAMILY SSF52777 29 166 6.23E-9 T 29-03-2018 MSG_RS15515 acac5feabad9906cce0f7b0e856df301 463 Gene3D G3DSA:3.30.559.10 2 186 4.4E-6 T 29-03-2018 MSG_RS15515 acac5feabad9906cce0f7b0e856df301 463 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 462 1.3E-156 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS15515 acac5feabad9906cce0f7b0e856df301 463 Pfam PF06974 Protein of unknown function (DUF1298) 310 458 3.9E-34 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS15515 acac5feabad9906cce0f7b0e856df301 463 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 269 1.2E-78 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 SUPERFAMILY SSF51905 8 222 5.83E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 Pfam PF13454 FAD-NAD(P)-binding 8 146 4.2E-6 T 29-03-2018 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 Gene3D G3DSA:3.50.50.60 1 169 2.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 3.3E-5 T 29-03-2018 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 3.3E-5 T 29-03-2018 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.3E-5 T 29-03-2018 MSG_RS17300 9e2d185eae34783c7e1fe4c9a12072d0 345 Gene3D G3DSA:3.40.50.720 170 300 0.0011 T 29-03-2018 MSG_RS18515 87179c873741ccfd4403b282bd7e862b 872 Gene3D G3DSA:3.40.50.300 536 868 6.2E-11 T 29-03-2018 MSG_RS18515 87179c873741ccfd4403b282bd7e862b 872 SUPERFAMILY SSF52540 743 860 1.47E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18515 87179c873741ccfd4403b282bd7e862b 872 SUPERFAMILY SSF52540 2 228 1.47E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18515 87179c873741ccfd4403b282bd7e862b 872 Gene3D G3DSA:3.40.50.300 1 535 1.7E-17 T 29-03-2018 MSG_RS18515 87179c873741ccfd4403b282bd7e862b 872 Pfam PF13175 AAA ATPase domain 2 60 4.1E-9 T 29-03-2018 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 SUPERFAMILY SSF55486 8 663 9.08E-212 T 29-03-2018 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 Gene3D G3DSA:3.40.390.10 15 252 4.0E-12 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 Gene3D G3DSA:3.40.390.10 327 664 6.4E-113 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 487 503 4.6E-23 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 561 572 4.6E-23 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 448 460 4.6E-23 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 466 478 4.6E-23 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 Pfam PF01431 Peptidase family M13 456 660 2.1E-78 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MSG_RS01885 81eced71ca0504a17417f3d619fe7235 664 Pfam PF05649 Peptidase family M13 21 404 5.1E-98 T 29-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MSG_RS14145 6b44ee65a490682ac0f88bac3b35ab84 252 Gene3D G3DSA:3.40.50.700 1 175 1.5E-34 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14145 6b44ee65a490682ac0f88bac3b35ab84 252 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 151 3.5E-23 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14145 6b44ee65a490682ac0f88bac3b35ab84 252 SUPERFAMILY SSF56770 2 213 6.67E-43 T 29-03-2018 MSG_RS09265 83de398041c49fdb37d84ad54bfbb4b3 119 Pfam PF05305 Protein of unknown function (DUF732) 15 109 5.5E-14 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS24440 9f6d1915b27a45cdf4e1020c11ee00e3 284 SUPERFAMILY SSF51735 2 265 1.71E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24440 9f6d1915b27a45cdf4e1020c11ee00e3 284 Pfam PF13460 NAD(P)H-binding 7 175 2.3E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24440 9f6d1915b27a45cdf4e1020c11ee00e3 284 Gene3D G3DSA:3.40.50.720 60 284 5.2E-11 T 29-03-2018 MSG_RS24440 9f6d1915b27a45cdf4e1020c11ee00e3 284 Gene3D G3DSA:3.40.50.720 1 59 6.1E-10 T 29-03-2018 MSG_RS08305 56ef082999a3c071ba39d6339f7ebe0d 168 Gene3D G3DSA:2.70.70.10 14 158 2.3E-16 T 29-03-2018 MSG_RS08305 56ef082999a3c071ba39d6339f7ebe0d 168 Pfam PF01551 Peptidase family M23 54 140 9.7E-10 T 29-03-2018 IPR016047 Peptidase M23 MSG_RS08305 56ef082999a3c071ba39d6339f7ebe0d 168 SUPERFAMILY SSF51261 47 156 2.77E-11 T 29-03-2018 IPR011055 Duplicated hybrid motif MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 8.4E-14 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 SUPERFAMILY SSF55048 129 183 1.1E-10 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 SUPERFAMILY SSF52151 183 300 1.02E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 SUPERFAMILY SSF52151 2 121 1.02E-59 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 Gene3D G3DSA:3.40.366.10 185 302 8.9E-24 T 29-03-2018 MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 Pfam PF00698 Acyl transferase domain 7 283 9.0E-22 T 29-03-2018 IPR014043 Acyl transferase MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 Gene3D G3DSA:3.30.70.250 139 184 1.1E-9 T 29-03-2018 MSG_RS15725 58a1dcd843a7fbd3d460c7bcaf9234c1 302 Gene3D G3DSA:3.40.366.10 1 138 8.1E-24 T 29-03-2018 MSG_RS13460 7db2d4380a41cd242db2aa6df02a8e69 102 Pfam PF14230 Domain of unknown function (DUF4333) 19 88 1.9E-14 T 29-03-2018 IPR025637 Domain of unknown function DUF4333 MSG_RS04200 3e8e7c3bde448a756b4436bf9a8054cb 336 SUPERFAMILY SSF52540 5 232 5.65E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS04200 3e8e7c3bde448a756b4436bf9a8054cb 336 Gene3D G3DSA:3.40.50.300 1 327 2.3E-58 T 29-03-2018 MSG_RS04200 3e8e7c3bde448a756b4436bf9a8054cb 336 Pfam PF00005 ABC transporter 21 168 5.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS04200 3e8e7c3bde448a756b4436bf9a8054cb 336 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS04200 3e8e7c3bde448a756b4436bf9a8054cb 336 SMART SM00382 29 225 4.2E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS19015 f72544a1daebd504d3ba553d5c4aefc5 267 Pfam PF09037 Stf0 sulphotransferase 7 259 2.6E-102 T 29-03-2018 IPR024628 Sulphotransferase Stf0, domain MetaCyc: PWY-7746 MSG_RS19015 f72544a1daebd504d3ba553d5c4aefc5 267 Gene3D G3DSA:3.40.50.300 3 267 6.8E-30 T 29-03-2018 MSG_RS19015 f72544a1daebd504d3ba553d5c4aefc5 267 PIRSF PIRSF021497 1 267 4.4E-108 T 29-03-2018 IPR015124 Trehalose 2-sulfotransferase GO:0016740 MetaCyc: PWY-7746 MSG_RS19015 f72544a1daebd504d3ba553d5c4aefc5 267 SUPERFAMILY SSF52540 3 266 8.35E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03010 2fd0255766e367a1858d75ab1e8ff13f 202 Gene3D G3DSA:3.90.79.10 11 147 4.1E-22 T 29-03-2018 MSG_RS03010 2fd0255766e367a1858d75ab1e8ff13f 202 SUPERFAMILY SSF55811 7 144 6.36E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS03010 2fd0255766e367a1858d75ab1e8ff13f 202 Pfam PF00293 NUDIX domain 14 132 3.6E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS03010 2fd0255766e367a1858d75ab1e8ff13f 202 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 PIRSF PIRSF005917 1 278 2.1E-86 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 85 96 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 208 2.5E-27 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 Gene3D G3DSA:3.30.950.10 116 228 2.0E-39 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 5 225 32.213 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 SUPERFAMILY SSF53790 4 223 6.54E-67 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9 273 1.5E-56 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MSG_RS20085 a0360740b9d2353315fdf796a3276d50 278 Gene3D G3DSA:3.40.1010.10 3 115 1.2E-29 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MSG_RS17945 f26f4e2d73820438820f1355e3646925 280 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 272 2.3E-49 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS17945 f26f4e2d73820438820f1355e3646925 280 SUPERFAMILY SSF52096 10 273 3.83E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS17945 f26f4e2d73820438820f1355e3646925 280 Gene3D G3DSA:3.90.226.10 3 279 1.7E-71 T 29-03-2018 MSG_RS07625 c141aa41fb94b657bdc2f46014ecf094 276 Pfam PF08241 Methyltransferase domain 66 157 6.8E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS07625 c141aa41fb94b657bdc2f46014ecf094 276 Gene3D G3DSA:3.40.50.150 33 254 6.9E-31 T 29-03-2018 MSG_RS07625 c141aa41fb94b657bdc2f46014ecf094 276 SUPERFAMILY SSF53335 43 212 6.54E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 SUPERFAMILY SSF53335 43 232 3.7E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 34 230 23.758 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 47 218 6.3E-41 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 PIRSF PIRSF003078 23 236 6.9E-45 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 Pfam PF02527 rRNA small subunit methyltransferase G 43 220 5.2E-53 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MSG_RS24690 a545a66312dc7461c37f2eca85c58ccc 249 Gene3D G3DSA:3.40.50.150 31 249 4.3E-34 T 29-03-2018 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 Gene3D G3DSA:3.60.120.10 22 501 6.2E-160 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 Pfam PF04715 Anthranilate synthase component I, N terminal region 33 174 1.1E-32 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 Pfam PF00425 chorismate binding enzyme 231 489 3.1E-93 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 SUPERFAMILY SSF56322 22 498 1.44E-150 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 32 497 7.4E-164 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 PRINTS PR00095 Anthranilate synthase component I signature 337 350 2.8E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 PRINTS PR00095 Anthranilate synthase component I signature 431 445 2.8E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 PRINTS PR00095 Anthranilate synthase component I signature 446 460 2.8E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS11215 81378377f9c221e97ad03b26502f8f7f 512 PRINTS PR00095 Anthranilate synthase component I signature 351 364 2.8E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MSG_RS00325 a6eda480919d14ae75babf4c27d1c66a 180 Pfam PF03551 Transcriptional regulator PadR-like family 6 81 2.8E-22 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal MSG_RS00325 a6eda480919d14ae75babf4c27d1c66a 180 SUPERFAMILY SSF46785 2 170 1.25E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00325 a6eda480919d14ae75babf4c27d1c66a 180 Gene3D G3DSA:1.10.10.10 1 90 2.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 Pfam PF00311 Phosphoenolpyruvate carboxylase 153 932 1.8E-264 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 Gene3D G3DSA:1.20.1440.90 296 418 3.6E-25 T 29-03-2018 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 583 595 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 SUPERFAMILY SSF51621 28 932 6.59E-285 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 20 932 19.176 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 156 167 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 416 436 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 155 168 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 758 784 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 623 652 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 267 282 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 581 601 5.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MSG_RS10470 bc0deee94edf4879426b0625a8ff01a2 932 Gene3D G3DSA:3.20.20.60 447 688 7.1E-4 T 29-03-2018 MSG_RS04685 cc17a4901f4fb4c956872c405cf1044c 306 Gene3D G3DSA:3.40.50.150 7 285 1.1E-59 T 29-03-2018 MSG_RS04685 cc17a4901f4fb4c956872c405cf1044c 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 22 278 3.3E-84 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS04685 cc17a4901f4fb4c956872c405cf1044c 306 SUPERFAMILY SSF53335 20 291 3.53E-79 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS04685 cc17a4901f4fb4c956872c405cf1044c 306 Pfam PF04072 Leucine carboxyl methyltransferase 24 206 4.9E-67 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS19460 98011ea7f82b704ea02d0a21c9e6a743 142 Pfam PF12120 Rifampin ADP-ribosyl transferase 17 114 1.1E-46 T 29-03-2018 IPR021975 DNA/RNA tunnel of bacterial DNA dependent RNA polymerase MSG_RS09255 5519d06eedbf2b2fba365430a13ad687 112 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 112 4.0E-12 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS09255 5519d06eedbf2b2fba365430a13ad687 112 PIRSF PIRSF010611 1 112 1.5E-45 T 29-03-2018 IPR016572 Uncharacterised conserved protein UCP010611 MSG_RS02460 72cff83eb246322c2c77cd4d445dc521 226 Pfam PF03734 L,D-transpeptidase catalytic domain 85 222 1.4E-5 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS02460 72cff83eb246322c2c77cd4d445dc521 226 Gene3D G3DSA:2.40.440.10 43 225 4.5E-8 T 29-03-2018 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 475 607 4.8E-30 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 SUPERFAMILY SSF56645 37 296 9.42E-43 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.3E-7 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 2.5E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 SUPERFAMILY SSF47203 292 467 5.32E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Gene3D G3DSA:1.10.540.10 32 150 3.0E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Gene3D G3DSA:2.40.110.10 160 274 2.3E-26 T 29-03-2018 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Gene3D G3DSA:1.20.140.10 275 475 5.2E-31 T 29-03-2018 MSG_RS02180 cea3410c8a0f1f5d88f04e6cf8aaae06 611 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 3.9E-18 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MSG_RS21725 0f990be17117b08f020df6ec6ecd0e39 100 SUPERFAMILY SSF49464 23 75 2.59E-8 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain MSG_RS21725 0f990be17117b08f020df6ec6ecd0e39 100 Gene3D G3DSA:2.60.40.10 17 98 1.9E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS21725 0f990be17117b08f020df6ec6ecd0e39 100 Pfam PF07210 Protein of unknown function (DUF1416) 2 99 4.1E-43 T 29-03-2018 IPR010814 Protein of unknown function DUF1416 MSG_RS05780 940773de155a55d6da12e914fc92d206 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 12 84 5.0E-29 T 29-03-2018 IPR009963 Protein of unknown function DUF1490 MSG_RS05780 940773de155a55d6da12e914fc92d206 93 Pfam PF07371 Protein of unknown function (DUF1490) 1 87 9.0E-40 T 29-03-2018 IPR009963 Protein of unknown function DUF1490 MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 30 50 3.1E-15 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 3.1E-15 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 3.1E-15 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 93 109 3.1E-15 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 293 8.1E-81 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 Gene3D G3DSA:1.20.120.570 134 299 2.1E-7 T 29-03-2018 MSG_RS22270 f6cc5d5d19d1506ec7896356a4535e80 354 Pfam PF02470 MlaD protein 41 115 4.9E-15 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 PIRSF PIRSF005624 4 222 1.2E-44 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 SUPERFAMILY SSF52540 17 218 1.53E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 Hamap MF_01389 Urease accessory protein UreG [ureG]. 24 222 44.1 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 26 219 3.3E-86 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 28 196 1.8E-35 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MSG_RS12965 b56c0d8e9ada201572d0b22c29c1b086 223 Gene3D G3DSA:3.40.50.300 25 221 1.7E-18 T 29-03-2018 MSG_RS24540 13ba9c5352e70fde8a1108fd75c892aa 227 Pfam PF05050 Methyltransferase FkbM domain 10 180 8.7E-16 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS24540 13ba9c5352e70fde8a1108fd75c892aa 227 Gene3D G3DSA:3.40.50.150 2 187 6.2E-26 T 29-03-2018 MSG_RS24540 13ba9c5352e70fde8a1108fd75c892aa 227 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 7 155 1.3E-27 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS24540 13ba9c5352e70fde8a1108fd75c892aa 227 SUPERFAMILY SSF53335 4 181 1.52E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS17065 32af4d801b784b22a336c7ad8ce5fda6 297 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS17065 32af4d801b784b22a336c7ad8ce5fda6 297 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 252 1.6E-47 T 29-03-2018 MSG_RS17065 32af4d801b784b22a336c7ad8ce5fda6 297 Gene3D G3DSA:3.20.20.60 2 294 5.9E-81 T 29-03-2018 MSG_RS17065 32af4d801b784b22a336c7ad8ce5fda6 297 SUPERFAMILY SSF51621 6 291 4.49E-86 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS18490 248156b45bcc214a3d50cd138e6a9605 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 323 3.7E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18490 248156b45bcc214a3d50cd138e6a9605 325 SUPERFAMILY SSF161098 89 159 5.49E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18490 248156b45bcc214a3d50cd138e6a9605 325 SUPERFAMILY SSF161098 187 306 5.49E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18490 248156b45bcc214a3d50cd138e6a9605 325 Gene3D G3DSA:1.10.3720.10 3 312 1.0E-37 T 29-03-2018 MSG_RS21540 c7990eba6f63b078d4a4551fa767a0bf 102 SUPERFAMILY SSF54909 8 87 6.74E-11 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS21540 c7990eba6f63b078d4a4551fa767a0bf 102 Gene3D G3DSA:3.30.70.100 1 87 5.8E-9 T 29-03-2018 MSG_RS02420 af4a7df428d8a89055a2e2e7e1a1b0dd 261 Pfam PF13489 Methyltransferase domain 11 179 8.4E-14 T 29-03-2018 MSG_RS02420 af4a7df428d8a89055a2e2e7e1a1b0dd 261 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 254 42.758 T 29-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS02420 af4a7df428d8a89055a2e2e7e1a1b0dd 261 Gene3D G3DSA:3.40.50.150 1 178 3.3E-27 T 29-03-2018 MSG_RS02420 af4a7df428d8a89055a2e2e7e1a1b0dd 261 SUPERFAMILY SSF53335 16 246 1.7E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS02420 af4a7df428d8a89055a2e2e7e1a1b0dd 261 Gene3D G3DSA:1.10.150.290 179 233 2.3E-24 T 29-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MSG_RS21555 f5a57c9dbf1ccfb6911302bc890a9f5d 146 Pfam PF02310 B12 binding domain 4 114 4.8E-22 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS21555 f5a57c9dbf1ccfb6911302bc890a9f5d 146 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 125 5.1E-44 T 29-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS21555 f5a57c9dbf1ccfb6911302bc890a9f5d 146 SUPERFAMILY SSF52242 3 124 1.83E-41 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS21555 f5a57c9dbf1ccfb6911302bc890a9f5d 146 Gene3D G3DSA:3.40.50.280 2 143 2.0E-34 T 29-03-2018 MSG_RS06555 ae6bfcba523cdeafc451209ff230d3e8 239 Gene3D G3DSA:3.90.550.10 2 225 3.4E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS06555 ae6bfcba523cdeafc451209ff230d3e8 239 Pfam PF00535 Glycosyl transferase family 2 14 176 2.1E-13 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS06555 ae6bfcba523cdeafc451209ff230d3e8 239 SUPERFAMILY SSF53448 11 220 7.03E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS19435 e7d7287cde83969e1d0d1d7d338eaa4f 226 Gene3D G3DSA:3.90.1720.10 7 204 4.8E-22 T 29-03-2018 MSG_RS19435 e7d7287cde83969e1d0d1d7d338eaa4f 226 SUPERFAMILY SSF54001 10 129 1.18E-24 T 29-03-2018 MSG_RS19435 e7d7287cde83969e1d0d1d7d338eaa4f 226 SUPERFAMILY SSF54001 169 218 1.18E-24 T 29-03-2018 MSG_RS01865 71e017ed1050554a642363d5d8d4bcae 413 Pfam PF07690 Major Facilitator Superfamily 227 394 5.2E-9 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS01865 71e017ed1050554a642363d5d8d4bcae 413 Pfam PF07690 Major Facilitator Superfamily 28 196 2.0E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS01865 71e017ed1050554a642363d5d8d4bcae 413 Gene3D G3DSA:1.20.1250.20 212 408 2.9E-12 T 29-03-2018 MSG_RS01865 71e017ed1050554a642363d5d8d4bcae 413 Gene3D G3DSA:1.20.1250.20 11 204 1.6E-23 T 29-03-2018 MSG_RS01865 71e017ed1050554a642363d5d8d4bcae 413 SUPERFAMILY SSF103473 12 398 6.93E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS11590 b81a5761b8a306f5cafa883afddbfbf6 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 96 7.0E-38 T 29-03-2018 MSG_RS11590 b81a5761b8a306f5cafa883afddbfbf6 96 SUPERFAMILY SSF140453 2 95 2.62E-20 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS11590 b81a5761b8a306f5cafa883afddbfbf6 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 92 7.7E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS11590 b81a5761b8a306f5cafa883afddbfbf6 96 Gene3D G3DSA:1.10.287.1060 1 96 3.1E-13 T 29-03-2018 MSG_RS11590 b81a5761b8a306f5cafa883afddbfbf6 96 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.5E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS00630 b51daeb08cfff693269b77464ec5d3e2 243 Gene3D G3DSA:1.10.3720.10 1 243 1.9E-23 T 29-03-2018 MSG_RS00630 b51daeb08cfff693269b77464ec5d3e2 243 SUPERFAMILY SSF161098 45 226 5.36E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS00630 b51daeb08cfff693269b77464ec5d3e2 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 239 1.2E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS00235 1df93305b3d3c795382f437b82b64a0d 101 Pfam PF00934 PE family 10 94 1.2E-4 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS18130 a67c31ccf5f9fef2183c6151c7d88211 306 SUPERFAMILY SSF52833 46 153 2.28E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS18130 a67c31ccf5f9fef2183c6151c7d88211 306 Pfam PF14561 Tetratricopeptide repeat 229 306 1.1E-17 T 29-03-2018 MSG_RS18130 a67c31ccf5f9fef2183c6151c7d88211 306 Gene3D G3DSA:3.40.30.10 42 242 2.9E-29 T 29-03-2018 MSG_RS18130 a67c31ccf5f9fef2183c6151c7d88211 306 Pfam PF00085 Thioredoxin 49 149 2.9E-10 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 493 3.4E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 29-03-2018 IPR020845 AMP-binding, conserved site MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Pfam PF00501 AMP-binding enzyme 9 406 1.1E-72 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Gene3D G3DSA:3.40.50.980 164 317 2.8E-33 T 29-03-2018 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Gene3D G3DSA:2.30.38.10 318 399 1.9E-19 T 29-03-2018 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Gene3D G3DSA:3.40.50.980 7 163 3.7E-32 T 29-03-2018 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 Gene3D G3DSA:3.30.300.30 401 505 1.1E-23 T 29-03-2018 MSG_RS01960 92df8c5323476ef1f79532beef44ca56 505 SUPERFAMILY SSF56801 9 503 1.44E-124 T 29-03-2018 MSG_RS24230 0f7c9172fb82eff95bf94fbe5d2035e3 261 Gene3D G3DSA:3.40.1130.10 1 216 2.9E-42 T 29-03-2018 MSG_RS24230 0f7c9172fb82eff95bf94fbe5d2035e3 261 Pfam PF01553 Acyltransferase 24 149 4.3E-30 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS24230 0f7c9172fb82eff95bf94fbe5d2035e3 261 SMART SM00563 38 152 1.8E-31 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS24230 0f7c9172fb82eff95bf94fbe5d2035e3 261 SUPERFAMILY SSF69593 5 207 2.22E-31 T 29-03-2018 MSG_RS08455 8a31b02b0d50762b5abe7a292005e27c 157 SUPERFAMILY SSF46785 15 149 3.99E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08455 8a31b02b0d50762b5abe7a292005e27c 157 Pfam PF01475 Ferric uptake regulator family 23 129 2.6E-16 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MSG_RS08455 8a31b02b0d50762b5abe7a292005e27c 157 Gene3D G3DSA:1.10.10.10 16 104 2.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 Gene3D G3DSA:2.40.110.10 131 229 2.1E-9 T 29-03-2018 MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 SUPERFAMILY SSF56645 19 208 2.23E-23 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 SUPERFAMILY SSF47203 238 390 1.61E-22 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 Gene3D G3DSA:1.20.140.10 230 389 3.8E-14 T 29-03-2018 MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 Gene3D G3DSA:1.10.540.10 4 130 9.6E-4 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS02085 9e6fc738890ed230b4999cbea60cba8f 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 387 9.4E-13 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS16755 709c45ae66202575faa93ef4cfd9705e 174 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 38 174 2.0E-47 T 29-03-2018 IPR020235 Low molecular weight antigen MTB12 MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 77 140 9.6E-11 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 233 297 3.6E-13 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 SUPERFAMILY SSF50249 15 148 1.27E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 Gene3D G3DSA:2.40.50.140 236 302 8.7E-18 T 29-03-2018 MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 Gene3D G3DSA:2.40.50.140 80 148 8.5E-17 T 29-03-2018 MSG_RS22390 f202ab0008a81b7bf28f02b330c46d3c 329 SUPERFAMILY SSF50249 168 303 1.1E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS17450 5ea2285d4ddf309624f45d8adf2f560f 270 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 211 1.2E-28 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MSG_RS17450 5ea2285d4ddf309624f45d8adf2f560f 270 Gene3D G3DSA:3.20.20.60 2 223 9.5E-47 T 29-03-2018 MSG_RS17450 5ea2285d4ddf309624f45d8adf2f560f 270 SUPERFAMILY SSF51621 10 223 6.63E-63 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS17450 5ea2285d4ddf309624f45d8adf2f560f 270 PIRSF PIRSF015582 1 270 1.5E-75 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like MSG_RS10040 66b32b8367a6316957ea4c69c7ad04da 362 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 284 358 4.0E-16 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS10040 66b32b8367a6316957ea4c69c7ad04da 362 SUPERFAMILY SSF140459 12 185 8.89E-56 T 29-03-2018 MSG_RS10040 66b32b8367a6316957ea4c69c7ad04da 362 Pfam PF00823 PPE family 16 173 3.6E-55 T 29-03-2018 IPR000030 PPE family MSG_RS10040 66b32b8367a6316957ea4c69c7ad04da 362 Gene3D G3DSA:1.10.287.1060 30 116 2.8E-5 T 29-03-2018 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 Pfam PF00444 Ribosomal protein L36 2 37 4.7E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 1.2E-20 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 4.0E-9 T 29-03-2018 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 SUPERFAMILY SSF57840 2 37 6.93E-16 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04825 5068a9d24c4512125ff4483074c69312 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.573 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 Gene3D G3DSA:3.50.50.60 3 321 4.7E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 Gene3D G3DSA:3.90.700.10 322 450 1.3E-29 T 29-03-2018 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 SUPERFAMILY SSF56425 289 457 6.58E-30 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 Pfam PF00890 FAD binding domain 11 501 3.5E-83 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 SUPERFAMILY SSF51905 458 518 4.92E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 SUPERFAMILY SSF51905 6 139 4.92E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05705 08cd57badcbdb7147a4054ed48a4dad7 522 SUPERFAMILY SSF51905 171 249 4.92E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11150 39e2eb7516196b59170bdcc4d1d40ddd 137 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 128 6.9E-20 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS11150 39e2eb7516196b59170bdcc4d1d40ddd 137 Gene3D G3DSA:2.30.110.10 20 130 1.6E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS03460 68d73823e819b2db1675d75f9e9de9f2 168 Gene3D G3DSA:3.30.1460.10 1 141 3.0E-42 T 29-03-2018 MSG_RS03460 68d73823e819b2db1675d75f9e9de9f2 168 SUPERFAMILY SSF69635 3 133 9.1E-28 T 29-03-2018 MSG_RS03460 68d73823e819b2db1675d75f9e9de9f2 168 Pfam PF10722 Putative bacterial sensory transduction regulator 6 131 3.8E-26 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN MSG_RS05245 74b004b5a30a7b7bef2272dca006bec5 154 SUPERFAMILY SSF75217 4 152 1.31E-40 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS05245 74b004b5a30a7b7bef2272dca006bec5 154 Gene3D G3DSA:3.40.1280.10 2 153 3.6E-36 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS05245 74b004b5a30a7b7bef2272dca006bec5 154 Pfam PF00588 SpoU rRNA Methylase family 4 142 1.0E-29 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MSG_RS05245 74b004b5a30a7b7bef2272dca006bec5 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 29.988 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MSG_RS05245 74b004b5a30a7b7bef2272dca006bec5 154 PIRSF PIRSF029256 1 154 5.9E-56 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 SUPERFAMILY SSF90002 238 298 9.02E-7 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 SUPERFAMILY SSF90002 325 351 9.02E-7 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 SMART SM00833 235 351 9.1E-37 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 48 173 2.7E-10 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 Gene3D G3DSA:3.30.1220.10 206 351 2.3E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 Gene3D G3DSA:3.40.50.300 2 200 9.2E-7 T 29-03-2018 MSG_RS01065 54c22421f789279ec9993b87fae458f8 398 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 238 350 1.7E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MSG_RS14860 6ffa57e008baa35e71f10a4af10c2f73 419 Pfam PF02470 MlaD protein 55 128 3.5E-12 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS13090 95ebc447a7ac1fe6ff822c6714d4b718 183 Pfam PF11706 CGNR zinc finger 136 178 4.6E-17 T 29-03-2018 IPR021005 Zinc finger, CGNR MSG_RS13090 95ebc447a7ac1fe6ff822c6714d4b718 183 SUPERFAMILY SSF160904 4 177 2.88E-43 T 29-03-2018 MSG_RS13090 95ebc447a7ac1fe6ff822c6714d4b718 183 Gene3D G3DSA:1.10.3300.10 2 180 1.0E-44 T 29-03-2018 IPR023286 ABATE domain MSG_RS13090 95ebc447a7ac1fe6ff822c6714d4b718 183 Pfam PF07336 Putative stress-induced transcription regulator 8 130 1.5E-21 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 Gene3D G3DSA:3.40.50.720 1 258 9.0E-54 T 29-03-2018 MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 9.2E-43 T 29-03-2018 MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.5E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20855 15d9e43aaa6f4b0642f17be6f76e6007 261 SUPERFAMILY SSF51735 7 257 1.3E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13130 95cf63a2f64025cbca978f648ac68996 233 SUPERFAMILY SSF54909 117 192 4.83E-6 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS13130 95cf63a2f64025cbca978f648ac68996 233 Gene3D G3DSA:3.30.70.100 106 221 1.4E-13 T 29-03-2018 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 SUPERFAMILY SSF51905 507 563 4.13E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 SUPERFAMILY SSF51905 8 142 4.13E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 SUPERFAMILY SSF51905 212 333 4.13E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 Gene3D G3DSA:3.90.700.10 362 497 2.1E-30 T 29-03-2018 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 Pfam PF00890 FAD binding domain 20 548 2.8E-87 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 SUPERFAMILY SSF56425 324 500 4.53E-31 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS12170 7368e7ae03ab23f0096845b7753dd897 565 Gene3D G3DSA:3.50.50.60 2 361 7.6E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS03095 24683b108878a59dfcce0788299d0c77 548 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 82 506 3.7E-208 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MSG_RS03095 24683b108878a59dfcce0788299d0c77 548 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 81 508 55.937 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MSG_RS03095 24683b108878a59dfcce0788299d0c77 548 Pfam PF13667 ThiC-associated domain 19 72 9.7E-10 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MSG_RS03095 24683b108878a59dfcce0788299d0c77 548 Pfam PF01964 Radical SAM ThiC family 82 502 1.9E-200 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MSG_RS01510 6960fbd8564f74b77b3c8d60b3fc6a94 313 SUPERFAMILY SSF53335 17 294 1.25E-82 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01510 6960fbd8564f74b77b3c8d60b3fc6a94 313 Pfam PF04072 Leucine carboxyl methyltransferase 21 207 1.1E-65 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS01510 6960fbd8564f74b77b3c8d60b3fc6a94 313 Gene3D G3DSA:3.40.50.150 4 301 1.4E-61 T 29-03-2018 MSG_RS01510 6960fbd8564f74b77b3c8d60b3fc6a94 313 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 287 5.2E-92 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 Gene3D G3DSA:3.40.50.1820 6 274 1.1E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.7E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00412 Epoxide hydrolase signature 59 74 1.7E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00412 Epoxide hydrolase signature 227 243 1.7E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00412 Epoxide hydrolase signature 118 131 1.7E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 Pfam PF00561 alpha/beta hydrolase fold 33 133 6.9E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 SUPERFAMILY SSF53474 14 273 4.09E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 8.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 229 243 8.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 8.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS17615 28a1c6f463fdedcf2aecbb3c83985108 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 8.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS14245 354c9d4168d8e5cd2e2a270c9fd252f4 264 Pfam PF02405 Permease MlaE 50 255 8.9E-56 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS00355 30e0f8973d8332df22530435976af5e5 180 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 16 177 2.0E-27 T 29-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like MSG_RS00355 30e0f8973d8332df22530435976af5e5 180 Pfam PF10862 FcoT-like thioesterase domain 23 172 3.2E-49 T 29-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like MSG_RS20845 34e6272774cd957a020957f5db7ad529 471 SUPERFAMILY SSF75304 2 458 4.45E-116 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS20845 34e6272774cd957a020957f5db7ad529 471 ProSitePatterns PS00571 Amidases signature. 153 184 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MSG_RS20845 34e6272774cd957a020957f5db7ad529 471 Pfam PF01425 Amidase 24 446 9.0E-97 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS20845 34e6272774cd957a020957f5db7ad529 471 Gene3D G3DSA:3.90.1300.10 3 470 7.6E-121 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS22840 b3f3b5f18346ea86ec383dc331dd5fa7 158 Pfam PF11377 Protein of unknown function (DUF3180) 9 147 2.9E-37 T 29-03-2018 IPR021517 Protein of unknown function DUF3180 MSG_RS17470 a9b557ed96c7e7e597507ce978240560 535 Pfam PF01039 Carboxyl transferase domain 48 525 6.0E-151 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS17470 a9b557ed96c7e7e597507ce978240560 535 Gene3D G3DSA:3.90.226.10 273 529 1.5E-70 T 29-03-2018 MSG_RS17470 a9b557ed96c7e7e597507ce978240560 535 Gene3D G3DSA:3.90.226.10 15 272 5.3E-66 T 29-03-2018 MSG_RS17470 a9b557ed96c7e7e597507ce978240560 535 SUPERFAMILY SSF52096 237 517 1.06E-85 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS17470 a9b557ed96c7e7e597507ce978240560 535 SUPERFAMILY SSF52096 26 271 1.81E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 Gene3D G3DSA:3.40.50.720 3 251 1.0E-66 T 29-03-2018 MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 249 1.4E-58 T 29-03-2018 MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 SUPERFAMILY SSF51735 12 250 1.64E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS18380 7eeb74a03d0bc6d7fd60d9b772018f8f 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.9E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS20260 33539176c08e7432f9b81f96f386ba1a 529 Pfam PF01039 Carboxyl transferase domain 46 518 1.0E-139 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS20260 33539176c08e7432f9b81f96f386ba1a 529 SUPERFAMILY SSF52096 22 261 2.49E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS20260 33539176c08e7432f9b81f96f386ba1a 529 Gene3D G3DSA:3.90.226.10 20 259 3.2E-55 T 29-03-2018 MSG_RS20260 33539176c08e7432f9b81f96f386ba1a 529 Gene3D G3DSA:3.90.226.10 270 523 1.2E-56 T 29-03-2018 MSG_RS20260 33539176c08e7432f9b81f96f386ba1a 529 SUPERFAMILY SSF52096 230 510 8.48E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS06605 3c13d350b502f8f4c3bef634ea027c4a 132 Pfam PF16525 Haemophore, haem-binding 38 114 3.1E-28 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS06605 3c13d350b502f8f4c3bef634ea027c4a 132 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 40 115 1.4E-24 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 Gene3D G3DSA:1.10.630.10 7 405 1.3E-68 T 29-03-2018 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 196 218 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 138 154 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 277 288 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 322 337 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 344 353 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 89 100 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 155 170 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 294 321 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 PRINTS PR00359 B-class P450 signature 353 364 3.7E-41 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 SUPERFAMILY SSF48264 13 405 4.06E-92 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22015 097dcd74bfd7ebb7133db02a20f7f895 405 Pfam PF00067 Cytochrome P450 195 373 1.4E-20 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 5.0E-31 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.7E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 SUPERFAMILY SSF51735 14 255 6.84E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 Gene3D G3DSA:3.40.50.720 9 50 2.2E-8 T 29-03-2018 MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 Gene3D G3DSA:3.40.50.720 51 264 7.2E-56 T 29-03-2018 MSG_RS07185 15d7ce68fee1da69afbf93737d6dfcdb 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 253 1.4E-55 T 29-03-2018 MSG_RS03235 030ea2c9d29e6f93dd35852288ef5864 275 SUPERFAMILY SSF140459 6 173 1.05E-52 T 29-03-2018 MSG_RS03235 030ea2c9d29e6f93dd35852288ef5864 275 Pfam PF00823 PPE family 9 164 1.9E-53 T 29-03-2018 IPR000030 PPE family MSG_RS03235 030ea2c9d29e6f93dd35852288ef5864 275 Gene3D G3DSA:1.10.287.1060 25 113 6.8E-8 T 29-03-2018 MSG_RS12700 4880ab710b718ce9054df45a8d30046b 394 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 15 360 4.1E-100 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS12700 4880ab710b718ce9054df45a8d30046b 394 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 193 282 1.2E-23 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS10965 d67f9356e72c325b83495ba9df47be5d 252 Gene3D G3DSA:3.40.50.150 9 252 9.5E-16 T 29-03-2018 MSG_RS10965 d67f9356e72c325b83495ba9df47be5d 252 Pfam PF08241 Methyltransferase domain 53 139 4.3E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS10965 d67f9356e72c325b83495ba9df47be5d 252 SUPERFAMILY SSF53335 20 251 1.35E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23045 acdf1053f3fd1f56e95d2a83019e7216 281 SUPERFAMILY SSF56784 20 238 2.14E-29 T 29-03-2018 IPR023214 HAD-like domain MSG_RS23045 acdf1053f3fd1f56e95d2a83019e7216 281 Gene3D G3DSA:3.40.50.1000 20 243 7.0E-19 T 29-03-2018 IPR023214 HAD-like domain MSG_RS23045 acdf1053f3fd1f56e95d2a83019e7216 281 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 23 211 8.6E-24 T 29-03-2018 MSG_RS23045 acdf1053f3fd1f56e95d2a83019e7216 281 Pfam PF12710 haloacid dehalogenase-like hydrolase 24 209 9.4E-32 T 29-03-2018 MSG_RS23045 acdf1053f3fd1f56e95d2a83019e7216 281 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 23 222 2.0E-71 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MSG_RS23960 a10e516654f6647f9db872fa6942fc96 128 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 43 118 4.0E-27 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS23960 a10e516654f6647f9db872fa6942fc96 128 Pfam PF16525 Haemophore, haem-binding 41 117 2.3E-31 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS06545 753e7f919ce8243fe6509dd9cc0ed50d 257 Gene3D G3DSA:3.40.50.10320 45 240 2.1E-42 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS06545 753e7f919ce8243fe6509dd9cc0ed50d 257 Pfam PF02585 GlcNAc-PI de-N-acetylase 49 174 1.4E-26 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MSG_RS06545 753e7f919ce8243fe6509dd9cc0ed50d 257 SUPERFAMILY SSF102588 46 234 2.75E-43 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 MSG_RS09340 df870d592a546b9e3b359aca000fb513 119 Pfam PF05305 Protein of unknown function (DUF732) 6 95 2.6E-17 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS03650 aa3e00fd4a5f1e13ab4b36536dc4ce0e 381 Pfam PF00296 Luciferase-like monooxygenase 5 331 1.3E-78 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS03650 aa3e00fd4a5f1e13ab4b36536dc4ce0e 381 Gene3D G3DSA:3.20.20.30 1 367 4.4E-83 T 29-03-2018 MSG_RS03650 aa3e00fd4a5f1e13ab4b36536dc4ce0e 381 SUPERFAMILY SSF51679 4 360 1.77E-86 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS02015 99319d5d2d283e1c66d065c2816bdc26 261 SUPERFAMILY SSF52096 10 260 1.72E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS02015 99319d5d2d283e1c66d065c2816bdc26 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MSG_RS02015 99319d5d2d283e1c66d065c2816bdc26 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 260 4.9E-48 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS02015 99319d5d2d283e1c66d065c2816bdc26 261 Gene3D G3DSA:3.90.226.10 12 218 6.4E-60 T 29-03-2018 MSG_RS02015 99319d5d2d283e1c66d065c2816bdc26 261 Gene3D G3DSA:1.10.12.10 219 261 2.4E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal MSG_RS11735 cfce5f38076e3674eaf685e21526cf6e 250 Pfam PF01596 O-methyltransferase 57 208 6.6E-15 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MSG_RS11735 cfce5f38076e3674eaf685e21526cf6e 250 SUPERFAMILY SSF53335 34 218 4.69E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS11735 cfce5f38076e3674eaf685e21526cf6e 250 Gene3D G3DSA:3.40.50.150 57 243 1.9E-28 T 29-03-2018 MSG_RS18635 309d6f4545b3daec8a9fde78278bf6b1 201 Gene3D G3DSA:1.10.357.10 63 197 9.8E-15 T 29-03-2018 MSG_RS18635 309d6f4545b3daec8a9fde78278bf6b1 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 52 1.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS18635 309d6f4545b3daec8a9fde78278bf6b1 201 SUPERFAMILY SSF46689 9 78 1.8E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18635 309d6f4545b3daec8a9fde78278bf6b1 201 SUPERFAMILY SSF48498 75 195 9.89E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS18635 309d6f4545b3daec8a9fde78278bf6b1 201 Gene3D G3DSA:1.10.10.60 2 62 6.7E-12 T 29-03-2018 MSG_RS15555 a5f2b5cb6cbdf6b25d2fcb477f47cca0 245 Gene3D G3DSA:1.20.5.1070 11 71 0.038 T 29-03-2018 MSG_RS15555 a5f2b5cb6cbdf6b25d2fcb477f47cca0 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 2.8E-11 T 29-03-2018 IPR003743 C4-type zinc ribbon domain MSG_RS15555 a5f2b5cb6cbdf6b25d2fcb477f47cca0 245 Gene3D G3DSA:1.20.5.320 72 179 3.2E-6 T 29-03-2018 MSG_RS24505 70b0629197a3aea09fb816efd92ce292 100 Pfam PF06013 Proteins of 100 residues with WXG 4 88 8.2E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24505 70b0629197a3aea09fb816efd92ce292 100 Gene3D G3DSA:1.10.287.1060 1 96 1.6E-11 T 29-03-2018 MSG_RS24505 70b0629197a3aea09fb816efd92ce292 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 2.3E-13 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24505 70b0629197a3aea09fb816efd92ce292 100 SUPERFAMILY SSF140453 3 99 7.98E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS05105 fcaab1ee97931fc62f3d79413c77e236 262 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 12 56 2.0E-17 T 29-03-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region MSG_RS15215 8612b8096312a15d9a1ed04017578e6d 461 Pfam PF01474 Class-II DAHP synthetase family 31 456 7.7E-188 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MSG_RS15215 8612b8096312a15d9a1ed04017578e6d 461 Gene3D G3DSA:3.20.20.70 236 403 2.9E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS15215 8612b8096312a15d9a1ed04017578e6d 461 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 26 461 1.2E-222 T 29-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MSG_RS15215 8612b8096312a15d9a1ed04017578e6d 461 SUPERFAMILY SSF51569 6 460 4.03E-190 T 29-03-2018 MSG_RS11790 87a57f05beac10fa1d3dc1b936eaf5a5 276 Pfam PF04199 Putative cyclase 17 168 2.1E-35 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MSG_RS11790 87a57f05beac10fa1d3dc1b936eaf5a5 276 Gene3D G3DSA:3.50.30.50 12 265 4.4E-68 T 29-03-2018 MSG_RS11790 87a57f05beac10fa1d3dc1b936eaf5a5 276 SUPERFAMILY SSF102198 207 262 1.44E-57 T 29-03-2018 MSG_RS11790 87a57f05beac10fa1d3dc1b936eaf5a5 276 SUPERFAMILY SSF102198 14 169 1.44E-57 T 29-03-2018 MSG_RS07290 8e7c3de4968f0d8aca8101ae7bfb026b 254 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 17 249 4.1E-28 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MSG_RS12430 41111471cc802ec80faa5704ed206d9a 305 Gene3D G3DSA:1.20.120.450 42 178 5.8E-16 T 29-03-2018 MSG_RS12430 41111471cc802ec80faa5704ed206d9a 305 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 47 279 4.0E-14 T 29-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MSG_RS12430 41111471cc802ec80faa5704ed206d9a 305 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 48 154 3.6E-13 T 29-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MSG_RS12430 41111471cc802ec80faa5704ed206d9a 305 SUPERFAMILY SSF109854 46 176 2.44E-18 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MSG_RS21510 19904628464c2cb1322af3ac59fe0065 80 Gene3D G3DSA:1.10.1470.10 9 79 2.4E-8 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS21510 19904628464c2cb1322af3ac59fe0065 80 SUPERFAMILY SSF69047 12 62 6.41E-5 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 Pfam PF13439 Glycosyltransferase Family 4 15 176 1.3E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 Gene3D G3DSA:3.40.50.2000 1 171 1.2E-17 T 29-03-2018 MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 Pfam PF00534 Glycosyl transferases group 1 194 364 3.1E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 Gene3D G3DSA:3.40.50.2000 172 381 5.2E-46 T 29-03-2018 MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 SUPERFAMILY SSF53756 1 385 3.34E-82 T 29-03-2018 MSG_RS18845 68376fd036a9374505eff81f75c3835c 387 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 385 9.7E-192 T 29-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 6.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 6.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 6.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 Pfam PF00106 short chain dehydrogenase 5 189 1.1E-53 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 SUPERFAMILY SSF51735 3 243 4.25E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12150 82b503325644838be7fa51afb978ef32 276 Gene3D G3DSA:3.40.50.720 2 276 1.4E-69 T 29-03-2018 MSG_RS12150 82b503325644838be7fa51afb978ef32 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12150 82b503325644838be7fa51afb978ef32 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.6E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS16445 57435795247973b11ab0c6723e6440f4 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 146 5.3E-26 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS16445 57435795247973b11ab0c6723e6440f4 150 Gene3D G3DSA:3.30.530.20 1 148 8.4E-29 T 29-03-2018 IPR023393 START-like domain MSG_RS16445 57435795247973b11ab0c6723e6440f4 150 SUPERFAMILY SSF55961 4 148 3.37E-25 T 29-03-2018 MSG_RS14190 072bbfe2ec5d88719e397aa3cfd2c153 72 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 21 68 6.0E-5 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 MSG_RS14190 072bbfe2ec5d88719e397aa3cfd2c153 72 SUPERFAMILY SSF143212 12 69 4.97E-9 T 29-03-2018 MSG_RS14190 072bbfe2ec5d88719e397aa3cfd2c153 72 Pfam PF08962 Domain of unknown function (DUF1876) 13 68 4.7E-6 T 29-03-2018 IPR015057 Protein of unknown function DUF1876 MSG_RS11290 c8e1427e90e950db6112cd33ba5f5261 197 Pfam PF03729 Short repeat of unknown function (DUF308) 82 151 4.0E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS11290 c8e1427e90e950db6112cd33ba5f5261 197 Pfam PF03729 Short repeat of unknown function (DUF308) 25 95 5.3E-12 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS11290 c8e1427e90e950db6112cd33ba5f5261 197 Pfam PF03729 Short repeat of unknown function (DUF308) 139 187 2.2E-8 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 SUPERFAMILY SSF52210 146 291 1.31E-32 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 289 3.0E-41 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Gene3D G3DSA:3.40.50.261 129 293 7.3E-31 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 SUPERFAMILY SSF56059 482 681 4.89E-30 T 29-03-2018 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Gene3D G3DSA:3.40.50.261 294 466 3.9E-30 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Pfam PF13549 ATP-grasp domain 481 681 1.7E-53 T 29-03-2018 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Pfam PF13380 CoA binding domain 13 136 1.5E-20 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Gene3D G3DSA:3.30.1490.20 497 552 8.2E-9 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 SUPERFAMILY SSF52210 296 457 4.84E-23 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 SUPERFAMILY SSF51735 5 133 8.72E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Gene3D G3DSA:3.40.50.720 4 128 3.3E-33 T 29-03-2018 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 SMART SM00881 8 103 8.5E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MSG_RS10065 67ca3d8e18f611a3f21aab2b9a48dfe5 683 Gene3D G3DSA:3.30.470.20 553 683 3.4E-41 T 29-03-2018 MSG_RS12590 ed9a965f11ffab24c9d29fd6085feef0 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 35 68 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MSG_RS12590 ed9a965f11ffab24c9d29fd6085feef0 446 SUPERFAMILY SSF56176 20 201 1.31E-45 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MSG_RS12590 ed9a965f11ffab24c9d29fd6085feef0 446 Pfam PF01565 FAD binding domain 35 169 1.6E-29 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MSG_RS12590 ed9a965f11ffab24c9d29fd6085feef0 446 Gene3D G3DSA:3.30.465.10 90 228 3.6E-34 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MSG_RS12590 ed9a965f11ffab24c9d29fd6085feef0 446 Gene3D G3DSA:3.30.43.10 7 88 2.2E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MSG_RS09235 214f6f6dad6ffe01babeac1b6a822fe4 377 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 79 1.2E-8 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS09235 214f6f6dad6ffe01babeac1b6a822fe4 377 Gene3D G3DSA:3.40.50.2000 2 210 1.4E-28 T 29-03-2018 MSG_RS09235 214f6f6dad6ffe01babeac1b6a822fe4 377 SUPERFAMILY SSF53756 2 376 1.57E-76 T 29-03-2018 MSG_RS09235 214f6f6dad6ffe01babeac1b6a822fe4 377 Gene3D G3DSA:3.40.50.2000 211 364 5.0E-28 T 29-03-2018 MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 Gene3D G3DSA:1.10.10.60 14 103 7.3E-14 T 29-03-2018 MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 SUPERFAMILY SSF48498 128 241 3.93E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 Gene3D G3DSA:1.10.357.10 104 241 4.6E-21 T 29-03-2018 MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 SUPERFAMILY SSF46689 48 127 1.18E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 Pfam PF16925 Bacterial transcriptional repressor C-terminal 130 235 2.9E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21860 3b061f1af3273aaddbacf01a74307d3c 263 Pfam PF00440 Bacterial regulatory proteins, tetR family 60 104 1.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS06300 a1084f7cac51d888bdcc75be3d0520a6 84 Gene3D G3DSA:3.40.30.10 1 83 3.2E-16 T 29-03-2018 MSG_RS06300 a1084f7cac51d888bdcc75be3d0520a6 84 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 6 79 9.2E-39 T 29-03-2018 IPR011915 Glutaredoxin-like protein, actinobacteria MSG_RS06300 a1084f7cac51d888bdcc75be3d0520a6 84 Pfam PF00462 Glutaredoxin 6 61 8.2E-14 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MSG_RS06300 a1084f7cac51d888bdcc75be3d0520a6 84 ProSitePatterns PS00194 Thioredoxin family active site. 6 24 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS06300 a1084f7cac51d888bdcc75be3d0520a6 84 SUPERFAMILY SSF52833 6 72 2.48E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS02520 dc2269c7175e2ca55c4cf262a27a4516 506 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 66 214 4.2E-8 T 29-03-2018 MSG_RS15220 cb00cbc952e7932a8c32a408e9b756f3 167 Hamap MF_00977 3'-5' exoribonuclease. 1 164 42.815 T 29-03-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 MSG_RS15220 cb00cbc952e7932a8c32a408e9b756f3 167 SUPERFAMILY SSF53098 4 160 8.02E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS15220 cb00cbc952e7932a8c32a408e9b756f3 167 Pfam PF16473 3' exoribonuclease, RNase T-like 2 159 5.3E-18 T 29-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain MSG_RS02830 a93ceee95a53e33f1a50d078075a4ea7 222 Pfam PF09335 SNARE associated Golgi protein 40 165 1.4E-20 T 29-03-2018 IPR032816 SNARE associated Golgi protein MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 SUPERFAMILY SSF46689 2 82 3.54E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS08170 c2b996d1a4c679eea57b7a98856b82de 200 Gene3D G3DSA:1.10.357.10 1 196 2.0E-22 T 29-03-2018 MSG_RS15730 8e430d74ddc4a7d6644d7961fe9f1875 114 Pfam PF00550 Phosphopantetheine attachment site 12 77 3.8E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS15730 8e430d74ddc4a7d6644d7961fe9f1875 114 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 79 1.0E-16 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MSG_RS15730 8e430d74ddc4a7d6644d7961fe9f1875 114 SUPERFAMILY SSF47336 3 109 1.07E-25 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS15730 8e430d74ddc4a7d6644d7961fe9f1875 114 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.605 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MSG_RS15730 8e430d74ddc4a7d6644d7961fe9f1875 114 Gene3D G3DSA:1.10.1200.10 1 114 2.0E-24 T 29-03-2018 MSG_RS18715 dbc01d1b59ca81e3a72a3de7d7b50037 291 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 285 9.4E-23 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 MSG_RS18715 dbc01d1b59ca81e3a72a3de7d7b50037 291 Gene3D G3DSA:3.40.190.10 23 155 3.4E-15 T 29-03-2018 MSG_RS18715 dbc01d1b59ca81e3a72a3de7d7b50037 291 SUPERFAMILY SSF53850 34 289 7.82E-24 T 29-03-2018 MSG_RS18715 dbc01d1b59ca81e3a72a3de7d7b50037 291 Gene3D G3DSA:3.40.190.10 169 289 7.4E-11 T 29-03-2018 MSG_RS09100 7eb3dcfe740ded64a1f392c75501b65f 664 Pfam PF13520 Amino acid permease 57 460 6.3E-25 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS13570 08b91c1e741ca81aa5b18fa0f7971b0a 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 3 230 5.2E-35 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MSG_RS13570 08b91c1e741ca81aa5b18fa0f7971b0a 245 SUPERFAMILY SSF51695 2 236 7.85E-53 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS13570 08b91c1e741ca81aa5b18fa0f7971b0a 245 Gene3D G3DSA:3.20.20.190 1 244 1.1E-55 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS07580 7ed63d3b2dc5fdc54654beb8f1faebb9 103 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 6 96 8.6E-20 T 29-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 94 5.3E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 Gene3D G3DSA:1.20.140.10 197 322 3.1E-20 T 29-03-2018 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 SUPERFAMILY SSF56645 10 97 2.09E-13 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 SUPERFAMILY SSF47203 199 343 4.83E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 Gene3D G3DSA:1.10.540.10 2 109 9.8E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MSG_RS17925 374d4f9582b5f3a8b6ce904aea41712f 352 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 200 330 4.8E-16 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MSG_RS12480 706a85f36ede6470cf43e8d0d04c931c 123 Pfam PF16817 Domain of unknown function (DUF5073) 1 121 5.8E-63 T 29-03-2018 IPR031816 Protein of unknown function DUF5073 MSG_RS23595 16dafa40009b6874ccfcc677dee67ac0 381 Gene3D G3DSA:3.20.20.30 14 375 7.4E-65 T 29-03-2018 MSG_RS23595 16dafa40009b6874ccfcc677dee67ac0 381 SUPERFAMILY SSF51679 16 375 3.27E-56 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS23595 16dafa40009b6874ccfcc677dee67ac0 381 Pfam PF00296 Luciferase-like monooxygenase 34 347 1.7E-52 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 Gene3D G3DSA:3.40.50.300 2 202 7.0E-41 T 29-03-2018 MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 216 22.713 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 166 2.8E-26 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 SUPERFAMILY SSF52540 3 190 1.14E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 PIRSF PIRSF006755 1 197 3.1E-30 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MSG_RS11075 8bb05cfa39d45545532cc772d2908e59 226 Pfam PF13500 AAA domain 4 193 1.4E-26 T 29-03-2018 MSG_RS04085 4a1a9fc7c493c0c9fa64e5de41c2b9e1 142 Gene3D G3DSA:3.10.129.10 2 139 1.8E-31 T 29-03-2018 MSG_RS04085 4a1a9fc7c493c0c9fa64e5de41c2b9e1 142 SUPERFAMILY SSF54637 6 131 2.42E-25 T 29-03-2018 IPR029069 HotDog domain MSG_RS04085 4a1a9fc7c493c0c9fa64e5de41c2b9e1 142 Pfam PF01575 MaoC like domain 16 121 3.8E-28 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 Gene3D G3DSA:3.30.370.10 1 62 3.7E-7 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 Gene3D G3DSA:3.40.1800.10 70 138 6.7E-8 T 29-03-2018 MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 Pfam PF01844 HNH endonuclease 97 134 1.7E-4 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 SUPERFAMILY SSF52038 2 35 2.75E-7 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 Pfam PF02720 Domain of unknown function (DUF222) 33 88 1.2E-11 T 29-03-2018 IPR003870 Domain of unknown function DUF222 MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 Pfam PF01337 Barstar (barnase inhibitor) 2 28 7.5E-7 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MSG_RS07480 f333beb3997e69ab2ecfb4e50c70da4c 200 SMART SM00507 79 130 3.1E-10 T 29-03-2018 IPR003615 HNH nuclease MSG_RS24410 14a8ce681038f14113a776261c9c6a7f 292 Pfam PF12697 Alpha/beta hydrolase family 43 286 1.3E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS24410 14a8ce681038f14113a776261c9c6a7f 292 SUPERFAMILY SSF53474 17 288 1.88E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24410 14a8ce681038f14113a776261c9c6a7f 292 Gene3D G3DSA:3.40.50.1820 14 289 2.9E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS20580 187cc1112f21851210f09df916befe6d 498 Pfam PF13810 Domain of unknown function (DUF4185) 167 494 7.0E-120 T 29-03-2018 IPR025442 Domain of unknown function DUF4185 MSG_RS09740 706d638569a93b15accfc2761787a43d 224 SUPERFAMILY SSF56281 4 220 4.19E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS09740 706d638569a93b15accfc2761787a43d 224 Pfam PF00753 Metallo-beta-lactamase superfamily 9 203 1.1E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS09740 706d638569a93b15accfc2761787a43d 224 SMART SM00849 12 203 6.3E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS09740 706d638569a93b15accfc2761787a43d 224 Gene3D G3DSA:3.60.15.10 1 224 3.1E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13055 afdd0b97ecdc7901e2deb38f0c5a1fb1 704 SUPERFAMILY SSF51735 2 213 1.27E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13055 afdd0b97ecdc7901e2deb38f0c5a1fb1 704 Gene3D G3DSA:3.90.25.10 161 251 0.0014 T 29-03-2018 MSG_RS13055 afdd0b97ecdc7901e2deb38f0c5a1fb1 704 Gene3D G3DSA:3.40.50.720 1 160 9.9E-13 T 29-03-2018 MSG_RS13055 afdd0b97ecdc7901e2deb38f0c5a1fb1 704 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 115 3.5E-7 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS03185 05724ecabe3f7b7ebaa939d60b79793e 240 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 41 237 1.3E-44 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MSG_RS03185 05724ecabe3f7b7ebaa939d60b79793e 240 Pfam PF02666 Phosphatidylserine decarboxylase 69 236 1.4E-30 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MSG_RS03185 05724ecabe3f7b7ebaa939d60b79793e 240 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 32 240 34.7 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 470 1.0E-20 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 Gene3D G3DSA:3.90.76.10 44 196 7.7E-8 T 29-03-2018 MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 SUPERFAMILY SSF53850 239 564 9.46E-53 T 29-03-2018 MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 SUPERFAMILY SSF53850 48 208 9.46E-53 T 29-03-2018 MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 Gene3D G3DSA:3.40.190.10 197 342 1.2E-16 T 29-03-2018 MSG_RS09710 f9418e3d5ae1c2438dc62d318cd3ce92 568 Gene3D G3DSA:3.10.105.10 343 536 1.2E-25 T 29-03-2018 MSG_RS22120 597100a0564d8c79d3a9eb1cec892a73 265 Pfam PF05305 Protein of unknown function (DUF732) 135 218 3.1E-12 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS02010 53e334defb8669c0035b134a01bf1ab7 469 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 263 2.2E-81 T 29-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS02010 53e334defb8669c0035b134a01bf1ab7 469 Gene3D G3DSA:3.30.559.10 2 199 5.3E-5 T 29-03-2018 MSG_RS02010 53e334defb8669c0035b134a01bf1ab7 469 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 453 2.6E-142 T 29-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS02010 53e334defb8669c0035b134a01bf1ab7 469 Pfam PF06974 Protein of unknown function (DUF1298) 302 447 7.3E-33 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS02010 53e334defb8669c0035b134a01bf1ab7 469 SUPERFAMILY SSF52777 32 167 7.56E-10 T 29-03-2018 MSG_RS02565 ee120be73a37b6f2b31662698789ae67 268 Pfam PF03734 L,D-transpeptidase catalytic domain 165 266 1.9E-13 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS02565 ee120be73a37b6f2b31662698789ae67 268 SUPERFAMILY SSF141523 164 266 9.68E-25 T 29-03-2018 MSG_RS02565 ee120be73a37b6f2b31662698789ae67 268 Gene3D G3DSA:2.40.440.10 117 268 3.7E-22 T 29-03-2018 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 Pfam PF03176 MMPL family 58 388 4.9E-109 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 Pfam PF03176 MMPL family 610 944 2.4E-103 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 SUPERFAMILY SSF82866 149 360 3.27E-27 T 29-03-2018 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 TIGRFAM TIGR00833 actII: transport protein 25 936 0.0 T 29-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 Gene3D G3DSA:1.20.1640.10 152 360 7.2E-29 T 29-03-2018 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 Gene3D G3DSA:1.20.1640.10 717 933 1.0E-26 T 29-03-2018 MSG_RS10875 b940fc1c199f761fa997b9fc4a98dc97 968 SUPERFAMILY SSF82866 708 936 8.89E-27 T 29-03-2018 MSG_RS17195 443df75e6b3fff3402f23731fcf3f288 364 SUPERFAMILY SSF52518 33 363 6.61E-80 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS17195 443df75e6b3fff3402f23731fcf3f288 364 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 79 226 2.3E-29 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MSG_RS17195 443df75e6b3fff3402f23731fcf3f288 364 Gene3D G3DSA:3.40.50.970 21 105 2.2E-19 T 29-03-2018 MSG_RS17195 443df75e6b3fff3402f23731fcf3f288 364 Gene3D G3DSA:3.40.50.970 106 350 3.6E-40 T 29-03-2018 MSG_RS02820 04be235466aa38b286abca664a94f189 380 Pfam PF03663 Glycosyl hydrolase family 76 10 349 4.7E-32 T 29-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 MSG_RS02820 04be235466aa38b286abca664a94f189 380 Gene3D G3DSA:1.50.10.20 3 375 2.1E-44 T 29-03-2018 MSG_RS02820 04be235466aa38b286abca664a94f189 380 PIRSF PIRSF021505 1 378 2.9E-88 T 29-03-2018 IPR014512 Predicted O-glycosyl hydrolase MSG_RS02820 04be235466aa38b286abca664a94f189 380 SUPERFAMILY SSF48208 23 305 2.47E-25 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 SUPERFAMILY SSF89963 5 89 3.4E-26 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 7.9E-62 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 SUPERFAMILY SSF89963 91 163 8.63E-26 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 Gene3D G3DSA:3.30.70.860 98 163 1.8E-31 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 26.679 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MSG_RS03930 ca3d0ab1aa19a0ea375badc8b1fe782a 163 Gene3D G3DSA:3.30.70.990 12 97 4.8E-30 T 29-03-2018 IPR035570 UPF0234 N-terminal domain MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 Gene3D G3DSA:3.20.20.100 5 94 1.6E-18 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 Pfam PF00248 Aldo/keto reductase family 31 87 3.9E-6 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 Pfam PF00248 Aldo/keto reductase family 131 192 3.5E-8 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 Gene3D G3DSA:3.20.20.100 95 208 1.7E-22 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 160 175 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MSG_RS07945 dce92cc012948a12d4602a92b09461a9 209 SUPERFAMILY SSF51430 9 198 2.49E-43 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS04895 7bf9b9ace916d3b206f98d59bc023633 108 Pfam PF06013 Proteins of 100 residues with WXG 10 94 6.1E-14 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS04895 7bf9b9ace916d3b206f98d59bc023633 108 Gene3D G3DSA:1.10.287.850 8 100 5.6E-14 T 29-03-2018 MSG_RS04895 7bf9b9ace916d3b206f98d59bc023633 108 SUPERFAMILY SSF140453 9 101 4.58E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 Pfam PF00561 alpha/beta hydrolase fold 30 284 4.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 SUPERFAMILY SSF53474 5 297 2.96E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 Gene3D G3DSA:3.40.50.1820 2 296 5.8E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 PRINTS PR00412 Epoxide hydrolase signature 33 51 2.5E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 PRINTS PR00412 Epoxide hydrolase signature 99 112 2.5E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 PRINTS PR00412 Epoxide hydrolase signature 273 295 2.5E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS19370 e0311cdd8b5e79dfb86d990157d1efa6 300 PRINTS PR00412 Epoxide hydrolase signature 53 68 2.5E-19 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS09250 8f957f22513bd9fffd81f383f6d18ec3 350 Gene3D G3DSA:3.20.20.370 54 338 3.0E-38 T 29-03-2018 MSG_RS09250 8f957f22513bd9fffd81f383f6d18ec3 350 Pfam PF01522 Polysaccharide deacetylase 94 297 2.2E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS09250 8f957f22513bd9fffd81f383f6d18ec3 350 SUPERFAMILY SSF88713 221 313 2.03E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS09250 8f957f22513bd9fffd81f383f6d18ec3 350 SUPERFAMILY SSF88713 59 137 2.03E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 35 105 6.0E-27 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 SMART SM01409 42 106 1.8E-12 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 Gene3D G3DSA:3.90.940.10 36 110 2.9E-19 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 Pfam PF01192 RNA polymerase Rpb6 42 104 1.3E-13 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 SUPERFAMILY SSF63562 35 106 5.58E-22 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MSG_RS10260 60a3758266ef2b20d353d274f016fef6 110 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 35 107 14.335 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 364 379 2.8E-8 T 29-03-2018 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 26 48 2.8E-8 T 29-03-2018 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 2.8E-8 T 29-03-2018 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 SUPERFAMILY SSF51905 25 248 6.59E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 SUPERFAMILY SSF51905 295 470 5.18E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 4.5E-5 T 29-03-2018 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 4.5E-5 T 29-03-2018 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 Gene3D G3DSA:3.50.50.60 185 503 1.6E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 Gene3D G3DSA:3.50.50.60 21 184 1.0E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00935 b10e2b7a49f3d599e8440bcbb6a27de8 521 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 29 232 1.1E-16 T 29-03-2018 MSG_RS14280 5cb270a0a05a04b1186e8e3c027799d4 516 Pfam PF02470 MlaD protein 39 112 4.3E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS14280 5cb270a0a05a04b1186e8e3c027799d4 516 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 294 3.1E-79 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS14280 5cb270a0a05a04b1186e8e3c027799d4 516 Gene3D G3DSA:1.10.287.500 136 287 0.0013 T 29-03-2018 MSG_RS08690 d34bd547a9781c0235c4b2af4ae0bb02 154 Gene3D G3DSA:1.25.40.10 16 152 8.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 5 625 9.8E-236 T 29-03-2018 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 368 393 - T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 Gene3D G3DSA:3.40.50.280 492 625 1.4E-19 T 29-03-2018 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 Gene3D G3DSA:3.20.20.240 47 486 8.4E-124 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 SUPERFAMILY SSF52242 477 625 2.75E-31 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 Pfam PF01642 Methylmalonyl-CoA mutase 49 534 5.5E-125 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS10725 cc4d4265e863f56f5c3dcdf17562ee82 625 SUPERFAMILY SSF51703 35 528 1.86E-128 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MSG_RS22600 dab9806b3d422daee53f4e006eb2aa8e 389 Pfam PF00155 Aminotransferase class I and II 32 381 3.6E-55 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS22600 dab9806b3d422daee53f4e006eb2aa8e 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MSG_RS22600 dab9806b3d422daee53f4e006eb2aa8e 389 Gene3D G3DSA:3.90.1150.10 274 386 6.4E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS22600 dab9806b3d422daee53f4e006eb2aa8e 389 SUPERFAMILY SSF53383 9 385 9.47E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS22600 dab9806b3d422daee53f4e006eb2aa8e 389 Gene3D G3DSA:3.40.640.10 41 273 2.5E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 65 118 2.0E-22 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 83 104 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 Pfam PF00374 Nickel-dependent hydrogenase 180 246 1.3E-7 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 SUPERFAMILY SSF143243 9 156 2.09E-30 T 29-03-2018 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 Gene3D G3DSA:1.10.645.10 140 333 2.1E-43 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 10 117 5.8E-17 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 256 412 5.5E-20 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 SUPERFAMILY SSF56762 139 488 3.79E-80 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18455 6ad5a0a97ab2a48473d3b3f2a946e52a 491 Gene3D G3DSA:1.10.645.10 334 481 7.1E-21 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS17400 69c40b148e7855c07a763f8e35e64226 185 SUPERFAMILY SSF46689 3 66 5.13E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS17400 69c40b148e7855c07a763f8e35e64226 185 Gene3D G3DSA:1.10.357.10 58 180 5.4E-18 T 29-03-2018 MSG_RS17400 69c40b148e7855c07a763f8e35e64226 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 53 3.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17400 69c40b148e7855c07a763f8e35e64226 185 Gene3D G3DSA:1.10.10.60 2 57 3.1E-9 T 29-03-2018 MSG_RS17400 69c40b148e7855c07a763f8e35e64226 185 SUPERFAMILY SSF48498 71 177 4.82E-18 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS16065 7964151251cfe3e922e83836e7f54c8e 243 Pfam PF10851 Protein of unknown function (DUF2652) 34 149 1.7E-42 T 29-03-2018 IPR020503 Uncharacterised protein family Rv2561 MSG_RS16065 7964151251cfe3e922e83836e7f54c8e 243 ProDom PD066345 MB2591 RV2561/RV2562/MT2638 34 239 3.0E-74 T 29-03-2018 IPR020503 Uncharacterised protein family Rv2561 MSG_RS16065 7964151251cfe3e922e83836e7f54c8e 243 Gene3D G3DSA:3.30.70.1230 2 193 2.0E-5 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS15370 760f1b7f89ea0c278dd8f8d675be1427 178 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 172 1.5E-54 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15370 760f1b7f89ea0c278dd8f8d675be1427 178 PIRSF PIRSF006135 1 176 3.4E-55 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MSG_RS15370 760f1b7f89ea0c278dd8f8d675be1427 178 Gene3D G3DSA:3.40.50.300 3 174 3.1E-55 T 29-03-2018 MSG_RS15370 760f1b7f89ea0c278dd8f8d675be1427 178 SUPERFAMILY SSF52540 3 174 2.48E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS19065 2a4502f84c877edcceea8b11817fd970 425 SUPERFAMILY SSF53474 138 387 1.13E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19065 2a4502f84c877edcceea8b11817fd970 425 Gene3D G3DSA:3.40.50.1820 109 415 4.5E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS19065 2a4502f84c877edcceea8b11817fd970 425 Pfam PF07859 alpha/beta hydrolase fold 177 385 4.1E-18 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS22805 d8cc8283421034e8e3a1c6a101dff43c 112 Pfam PF11774 Lsr2 1 111 3.7E-43 T 29-03-2018 IPR024412 Lsr2 MSG_RS22805 d8cc8283421034e8e3a1c6a101dff43c 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 108 2.0E-40 T 29-03-2018 IPR024412 Lsr2 MSG_RS21415 605c0bac6b7455b9916f424e795b67fb 220 SUPERFAMILY SSF46689 6 84 1.33E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21415 605c0bac6b7455b9916f424e795b67fb 220 Gene3D G3DSA:1.10.357.10 1 220 4.1E-27 T 29-03-2018 MSG_RS21415 605c0bac6b7455b9916f424e795b67fb 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 66 2.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS23165 6494adfc7065d6ef48c1efd22ae74a40 116 Pfam PF02467 Transcription factor WhiB 31 93 1.5E-21 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS23165 6494adfc7065d6ef48c1efd22ae74a40 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 20 98 16.827 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 Gene3D G3DSA:3.20.20.80 37 500 1.6E-121 T 29-03-2018 MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 Pfam PF16657 Maltogenic Amylase, C-terminal domain 501 580 3.0E-23 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 43 583 2.2E-286 T 29-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 SMART SM00642 51 453 7.5E-119 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 SUPERFAMILY SSF51011 506 583 1.36E-16 T 29-03-2018 MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 SUPERFAMILY SSF51445 391 498 1.23E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 SUPERFAMILY SSF51445 41 364 1.23E-131 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 Gene3D G3DSA:2.60.40.1180 501 591 8.3E-23 T 29-03-2018 MSG_RS01240 5a9779a0bbfde00f0fcf42e07f362769 591 Pfam PF00128 Alpha amylase, catalytic domain 66 422 1.5E-77 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 Pfam PF00067 Cytochrome P450 287 375 3.0E-13 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 SUPERFAMILY SSF48264 10 408 9.04E-81 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 165 180 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 148 164 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 351 360 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 301 328 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 329 344 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 360 371 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 205 227 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 102 113 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 PRINTS PR00359 B-class P450 signature 284 295 6.5E-46 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS22500 43f5f32499b9cc33cc79d70d7f2f84dd 416 Gene3D G3DSA:1.10.630.10 3 415 6.6E-64 T 29-03-2018 MSG_RS14910 082819117cd25e9dbe1a7cf601b0429f 271 Pfam PF00459 Inositol monophosphatase family 50 265 3.4E-24 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MSG_RS14910 082819117cd25e9dbe1a7cf601b0429f 271 Gene3D G3DSA:3.40.190.80 163 270 7.9E-20 T 29-03-2018 MSG_RS14910 082819117cd25e9dbe1a7cf601b0429f 271 Gene3D G3DSA:3.30.540.10 12 162 3.1E-23 T 29-03-2018 MSG_RS14910 082819117cd25e9dbe1a7cf601b0429f 271 SUPERFAMILY SSF56655 15 268 7.98E-46 T 29-03-2018 MSG_RS14910 082819117cd25e9dbe1a7cf601b0429f 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 88 101 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MSG_RS12010 5a373f9fbb290b5f4d102486bbfd4b06 491 Gene3D G3DSA:1.20.1250.20 22 229 4.1E-35 T 29-03-2018 MSG_RS12010 5a373f9fbb290b5f4d102486bbfd4b06 491 SUPERFAMILY SSF103473 8 473 4.05E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS12010 5a373f9fbb290b5f4d102486bbfd4b06 491 Gene3D G3DSA:1.20.1250.20 267 486 1.2E-24 T 29-03-2018 MSG_RS12010 5a373f9fbb290b5f4d102486bbfd4b06 491 Pfam PF00083 Sugar (and other) transporter 67 474 4.8E-49 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MSG_RS06685 08d52b8f36fe1ab291022c731d30a43c 329 PIRSF PIRSF002849 1 321 3.2E-128 T 29-03-2018 MSG_RS06685 08d52b8f36fe1ab291022c731d30a43c 329 SUPERFAMILY SSF52540 19 296 1.08E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06685 08d52b8f36fe1ab291022c731d30a43c 329 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 175 5.3E-63 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MSG_RS06685 08d52b8f36fe1ab291022c731d30a43c 329 Gene3D G3DSA:1.10.8.300 208 316 3.4E-31 T 29-03-2018 MSG_RS06685 08d52b8f36fe1ab291022c731d30a43c 329 Gene3D G3DSA:3.40.50.300 27 193 1.6E-27 T 29-03-2018 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 SUPERFAMILY SSF69864 172 395 5.76E-83 T 29-03-2018 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 Gene3D G3DSA:3.40.50.620 3 161 3.2E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 Pfam PF00764 Arginosuccinate synthase 6 392 1.1E-183 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 Gene3D G3DSA:3.90.1260.10 162 353 1.0E-73 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 394 6.3E-142 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 397 50.947 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 Gene3D G3DSA:1.20.5.470 363 395 2.1E-6 T 29-03-2018 MSG_RS11525 b882b027d82293a611f23e639d5b6fc3 401 SUPERFAMILY SSF52402 3 171 5.73E-41 T 29-03-2018 MSG_RS02065 85c087915ae6f6cd23defaa20d63b72c 373 Pfam PF01757 Acyltransferase family 1 333 6.5E-23 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS24340 0cdff17a04cd67109d81728f334b6f81 230 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 4.0E-18 T 29-03-2018 IPR001727 Gdt1 family MSG_RS24340 0cdff17a04cd67109d81728f334b6f81 230 Pfam PF01169 Uncharacterized protein family UPF0016 105 178 2.1E-19 T 29-03-2018 IPR001727 Gdt1 family MSG_RS19345 0a37118953bdb7bf54ebdcbc4a576079 174 Pfam PF07681 DoxX 11 96 6.4E-21 T 29-03-2018 IPR032808 DoxX family MSG_RS02815 21352488a8d294bb500622e9632c2fdb 468 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 452 2.2E-205 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MSG_RS02815 21352488a8d294bb500622e9632c2fdb 468 Gene3D G3DSA:1.10.220.70 56 143 1.4E-37 T 29-03-2018 MSG_RS02815 21352488a8d294bb500622e9632c2fdb 468 PIRSF PIRSF018788 1 467 3.7E-223 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MSG_RS02815 21352488a8d294bb500622e9632c2fdb 468 Gene3D G3DSA:3.20.20.70 146 455 1.3E-149 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS02815 21352488a8d294bb500622e9632c2fdb 468 Gene3D G3DSA:2.30.170.30 1 53 1.6E-23 T 29-03-2018 MSG_RS07425 97c1eee0b88be3e7292d49e4ff99d6a1 97 Pfam PF11829 Protein of unknown function (DUF3349) 6 95 1.1E-29 T 29-03-2018 IPR021784 Protein of unknown function DUF3349 MSG_RS15365 00b9d17f04dac3a1cd1531236c32b7d6 224 Pfam PF11241 Protein of unknown function (DUF3043) 36 220 1.3E-55 T 29-03-2018 IPR021403 Protein of unknown function DUF3043 MSG_RS02315 f00709069ca49bfb027aeddf53172b34 377 SUPERFAMILY SSF53474 28 160 9.84E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02315 f00709069ca49bfb027aeddf53172b34 377 SUPERFAMILY SSF53474 208 213 9.84E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02315 f00709069ca49bfb027aeddf53172b34 377 SUPERFAMILY SSF53474 304 375 9.84E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02315 f00709069ca49bfb027aeddf53172b34 377 Gene3D G3DSA:3.40.50.1820 5 375 9.4E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03360 72dc6ca3d1e6c7ad31f4b02cafeb6747 268 Gene3D G3DSA:3.10.129.10 14 142 6.5E-12 T 29-03-2018 MSG_RS03360 72dc6ca3d1e6c7ad31f4b02cafeb6747 268 SUPERFAMILY SSF54637 158 234 2.26E-12 T 29-03-2018 IPR029069 HotDog domain MSG_RS03360 72dc6ca3d1e6c7ad31f4b02cafeb6747 268 Gene3D G3DSA:3.10.129.10 155 263 2.2E-8 T 29-03-2018 MSG_RS03360 72dc6ca3d1e6c7ad31f4b02cafeb6747 268 SUPERFAMILY SSF54637 15 141 3.62E-20 T 29-03-2018 IPR029069 HotDog domain MSG_RS03360 72dc6ca3d1e6c7ad31f4b02cafeb6747 268 Pfam PF01643 Acyl-ACP thioesterase 16 266 5.4E-63 T 29-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 MSG_RS23275 a44320358ca2d659b1dcc368758efd9b 154 SUPERFAMILY SSF89095 4 154 4.34E-33 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 MSG_RS23275 a44320358ca2d659b1dcc368758efd9b 154 Gene3D G3DSA:1.10.1510.10 2 93 1.4E-27 T 29-03-2018 MSG_RS23275 a44320358ca2d659b1dcc368758efd9b 154 Gene3D G3DSA:1.10.10.410 94 154 8.2E-14 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MSG_RS23275 a44320358ca2d659b1dcc368758efd9b 154 Pfam PF09424 Yqey-like protein 5 154 3.6E-48 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial MSG_RS09060 de2c4b187a85da5e4daa37a11552daf0 158 Pfam PF11292 Protein of unknown function (DUF3093) 12 156 2.2E-50 T 29-03-2018 IPR021443 Protein of unknown function DUF3093 MSG_RS08940 74e0b2c2033ea6c0a0f85fa86d74ed29 747 Pfam PF08310 LGFP repeat 105 161 3.9E-9 T 29-03-2018 IPR013207 LGFP MSG_RS08940 74e0b2c2033ea6c0a0f85fa86d74ed29 747 Pfam PF08310 LGFP repeat 242 282 3.2E-8 T 29-03-2018 IPR013207 LGFP MSG_RS08940 74e0b2c2033ea6c0a0f85fa86d74ed29 747 Pfam PF08310 LGFP repeat 57 100 2.4E-6 T 29-03-2018 IPR013207 LGFP MSG_RS08940 74e0b2c2033ea6c0a0f85fa86d74ed29 747 Pfam PF08310 LGFP repeat 287 343 4.9E-8 T 29-03-2018 IPR013207 LGFP MSG_RS08940 74e0b2c2033ea6c0a0f85fa86d74ed29 747 Gene3D G3DSA:3.40.10.10 656 747 0.023 T 29-03-2018 IPR035451 Ada-like domain MSG_RS13050 7467aaf198971f27310e22d1b2437356 494 Gene3D G3DSA:3.40.47.10 6 258 8.5E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS13050 7467aaf198971f27310e22d1b2437356 494 Gene3D G3DSA:3.40.47.10 259 388 1.9E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS13050 7467aaf198971f27310e22d1b2437356 494 SUPERFAMILY SSF53901 282 395 1.65E-18 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS13050 7467aaf198971f27310e22d1b2437356 494 SUPERFAMILY SSF53901 28 123 7.79E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS13050 7467aaf198971f27310e22d1b2437356 494 SUPERFAMILY SSF53901 233 260 7.79E-5 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS16530 fc136bb31bdf58ec9ec1d79a981f58c6 373 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 161 295 7.4E-8 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS16530 fc136bb31bdf58ec9ec1d79a981f58c6 373 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 298 3.1E-74 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS16530 fc136bb31bdf58ec9ec1d79a981f58c6 373 Pfam PF02470 MlaD protein 40 113 1.5E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 Pfam PF00106 short chain dehydrogenase 6 191 9.1E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 179 0.0039 T 29-03-2018 MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 Gene3D G3DSA:3.40.50.720 1 242 1.6E-51 T 29-03-2018 MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.4E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS10285 68f93c26aa13248f1f2bc05034b1bc32 252 SUPERFAMILY SSF51735 1 228 1.93E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 Pfam PF08281 Sigma-70, region 4 122 173 4.3E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 49 80 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 SUPERFAMILY SSF88946 5 103 2.16E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 Gene3D G3DSA:1.10.1740.10 4 109 2.5E-22 T 29-03-2018 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 SUPERFAMILY SSF88659 117 174 8.94E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 Gene3D G3DSA:1.10.10.10 121 182 2.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 Pfam PF04542 Sigma-70 region 2 29 91 3.4E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS14625 4794ba5db6542e823fbc1333505cc2c2 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 173 5.6E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MSG_RS20355 5f1188175ab0d08b6b8fe726b175dce3 373 Pfam PF01551 Peptidase family M23 263 357 5.1E-31 T 29-03-2018 IPR016047 Peptidase M23 MSG_RS20355 5f1188175ab0d08b6b8fe726b175dce3 373 SUPERFAMILY SSF51261 234 361 1.6E-48 T 29-03-2018 IPR011055 Duplicated hybrid motif MSG_RS20355 5f1188175ab0d08b6b8fe726b175dce3 373 Gene3D G3DSA:2.70.70.10 138 364 1.0E-46 T 29-03-2018 MSG_RS02725 c6c0b0d2ae5dcdd3451c8b8f668af8e3 380 SUPERFAMILY SSF52540 203 373 2.98E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02725 c6c0b0d2ae5dcdd3451c8b8f668af8e3 380 SUPERFAMILY SSF52540 78 153 2.98E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS02725 c6c0b0d2ae5dcdd3451c8b8f668af8e3 380 Pfam PF13469 Sulfotransferase family 82 325 2.8E-40 T 29-03-2018 MSG_RS02725 c6c0b0d2ae5dcdd3451c8b8f668af8e3 380 Gene3D G3DSA:3.40.50.300 70 370 2.6E-36 T 29-03-2018 MSG_RS16825 0a131d6db8e5a1ff2d77b90f614a0306 310 Pfam PF13411 MerR HTH family regulatory protein 56 123 4.3E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS16825 0a131d6db8e5a1ff2d77b90f614a0306 310 Gene3D G3DSA:1.10.1660.10 46 307 7.1E-19 T 29-03-2018 MSG_RS16825 0a131d6db8e5a1ff2d77b90f614a0306 310 SUPERFAMILY SSF46955 56 128 9.89E-16 T 29-03-2018 IPR009061 Putative DNA-binding domain MSG_RS16825 0a131d6db8e5a1ff2d77b90f614a0306 310 SMART SM00422 56 124 5.3E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MSG_RS12080 d6fdfa7c332ef2d0d235a7e09d9edbee 252 Gene3D G3DSA:3.40.430.10 24 251 1.8E-35 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS12080 d6fdfa7c332ef2d0d235a7e09d9edbee 252 Pfam PF01872 RibD C-terminal domain 40 219 1.5E-22 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MSG_RS12080 d6fdfa7c332ef2d0d235a7e09d9edbee 252 SUPERFAMILY SSF53597 39 250 1.57E-29 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MSG_RS17025 bafe5ebf016c5d1dc5816532cc02776f 482 Gene3D G3DSA:3.40.50.410 278 472 3.0E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS17025 bafe5ebf016c5d1dc5816532cc02776f 482 PIRSF PIRSF010256 2 482 1.5E-133 T 29-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 MSG_RS17025 bafe5ebf016c5d1dc5816532cc02776f 482 Pfam PF05762 VWA domain containing CoxE-like protein 255 475 2.9E-60 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like MSG_RS07505 e8bb259dc38bd621889abb6cdc31b1ec 228 Gene3D G3DSA:3.90.640.20 143 227 2.1E-6 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 MSG_RS07505 e8bb259dc38bd621889abb6cdc31b1ec 228 Pfam PF11738 Protein of unknown function (DUF3298) 146 220 5.5E-13 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 MSG_RS15645 bea53e1f48e507c3e4c44c8771efcc9f 289 SUPERFAMILY SSF51197 8 280 1.03E-50 T 29-03-2018 MSG_RS15645 bea53e1f48e507c3e4c44c8771efcc9f 289 Gene3D G3DSA:3.60.130.10 2 281 7.5E-38 T 29-03-2018 MSG_RS15645 bea53e1f48e507c3e4c44c8771efcc9f 289 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 265 2.6E-29 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MSG_RS21970 ca3acda8976c9f64dd085cc7f1d862c4 226 Gene3D G3DSA:1.10.357.10 20 223 2.1E-21 T 29-03-2018 MSG_RS21970 ca3acda8976c9f64dd085cc7f1d862c4 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 5.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21970 ca3acda8976c9f64dd085cc7f1d862c4 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 5.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21970 ca3acda8976c9f64dd085cc7f1d862c4 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 3.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21970 ca3acda8976c9f64dd085cc7f1d862c4 226 SUPERFAMILY SSF46689 28 97 6.16E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS06535 db1fa72491d16875e8ebd5d5cce3ecc9 254 Gene3D G3DSA:3.60.10.10 1 252 9.2E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS06535 db1fa72491d16875e8ebd5d5cce3ecc9 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 244 1.2E-14 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS06535 db1fa72491d16875e8ebd5d5cce3ecc9 254 SUPERFAMILY SSF56219 1 251 2.36E-29 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MSG_RS00895 606e5307af830e2bc31a58a59a1852ff 460 SUPERFAMILY SSF53474 160 442 1.18E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00895 606e5307af830e2bc31a58a59a1852ff 460 Pfam PF00756 Putative esterase 183 366 1.6E-12 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS00895 606e5307af830e2bc31a58a59a1852ff 460 Gene3D G3DSA:3.40.50.1820 147 445 1.7E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05165 092cb6573b4f0f4a1a0f180d0505c020 213 Gene3D G3DSA:3.30.1050.10 111 212 9.7E-4 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MSG_RS05165 092cb6573b4f0f4a1a0f180d0505c020 213 Gene3D G3DSA:1.10.10.10 3 110 6.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05165 092cb6573b4f0f4a1a0f180d0505c020 213 SUPERFAMILY SSF46785 5 111 7.98E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS05165 092cb6573b4f0f4a1a0f180d0505c020 213 Pfam PF01638 HxlR-like helix-turn-helix 18 105 2.4E-17 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS22280 9ee7f316897b9de1efd1910b2c5ca0fa 400 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 298 9.1E-78 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS22280 9ee7f316897b9de1efd1910b2c5ca0fa 400 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 146 389 2.9E-52 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS22280 9ee7f316897b9de1efd1910b2c5ca0fa 400 Pfam PF02470 MlaD protein 41 117 5.2E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS06990 68ae48bb4a838036bef429b59b18b282 260 SUPERFAMILY SSF52096 4 228 2.11E-62 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS06990 68ae48bb4a838036bef429b59b18b282 260 Gene3D G3DSA:3.90.226.10 3 236 1.4E-60 T 29-03-2018 MSG_RS06990 68ae48bb4a838036bef429b59b18b282 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 215 4.0E-49 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 1.1E-15 T 29-03-2018 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 1.1E-15 T 29-03-2018 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-15 T 29-03-2018 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.1E-15 T 29-03-2018 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 SUPERFAMILY SSF51905 3 169 3.37E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 SUPERFAMILY SSF51905 268 350 3.37E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 Pfam PF01494 FAD binding domain 2 323 6.0E-17 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS18600 2ca05c3c2956f37f27d35ca9f67c0ea0 376 Gene3D G3DSA:3.50.50.60 1 319 2.1E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 Gene3D G3DSA:3.90.470.20 2 130 8.4E-32 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 SUPERFAMILY SSF56214 3 128 2.62E-22 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 106 6.2E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 129 21.102 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 129 3.1E-39 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MSG_RS17630 94ee436e1092a8aab7103a3181e12058 132 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 128 7.0E-5 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MSG_RS17850 a56e5dfa60cd3ae91ff6eb87620eca22 498 Gene3D G3DSA:3.90.226.10 249 495 1.8E-45 T 29-03-2018 MSG_RS17850 a56e5dfa60cd3ae91ff6eb87620eca22 498 SUPERFAMILY SSF52096 212 476 1.43E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS17850 a56e5dfa60cd3ae91ff6eb87620eca22 498 Gene3D G3DSA:3.90.226.10 1 248 7.1E-49 T 29-03-2018 MSG_RS17850 a56e5dfa60cd3ae91ff6eb87620eca22 498 Pfam PF01039 Carboxyl transferase domain 33 472 1.8E-83 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS17850 a56e5dfa60cd3ae91ff6eb87620eca22 498 SUPERFAMILY SSF52096 5 245 3.22E-52 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS14660 fe2acb9f509fee145942cbccbf1a1a76 802 Gene3D G3DSA:3.90.176.10 633 799 5.6E-36 T 29-03-2018 MSG_RS14660 fe2acb9f509fee145942cbccbf1a1a76 802 SUPERFAMILY SSF56399 648 798 8.0E-29 T 29-03-2018 MSG_RS14660 fe2acb9f509fee145942cbccbf1a1a76 802 Gene3D G3DSA:1.10.287.850 3 92 3.6E-4 T 29-03-2018 MSG_RS14660 fe2acb9f509fee145942cbccbf1a1a76 802 Gene3D G3DSA:1.10.287.1060 142 233 1.4E-4 T 29-03-2018 MSG_RS14660 fe2acb9f509fee145942cbccbf1a1a76 802 Pfam PF03496 ADP-ribosyltransferase exoenzyme 651 784 2.8E-12 T 29-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 MSG_RS02795 14581bb950dcabacd4cde9c869e44589 177 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 177 25.953 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS02795 14581bb950dcabacd4cde9c869e44589 177 SUPERFAMILY SSF53271 7 174 4.06E-35 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS02795 14581bb950dcabacd4cde9c869e44589 177 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 16 173 1.5E-36 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MSG_RS02795 14581bb950dcabacd4cde9c869e44589 177 Pfam PF00156 Phosphoribosyl transferase domain 44 155 2.1E-11 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MSG_RS02795 14581bb950dcabacd4cde9c869e44589 177 Gene3D G3DSA:3.40.50.2020 1 177 7.5E-35 T 29-03-2018 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 SUPERFAMILY SSF52540 745 1105 2.32E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 Gene3D G3DSA:3.40.50.300 940 1108 4.8E-31 T 29-03-2018 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 Pfam PF13482 RNase_H superfamily 304 493 2.7E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 Gene3D G3DSA:3.40.50.300 737 939 6.3E-24 T 29-03-2018 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 SUPERFAMILY SSF53098 347 498 9.43E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 Pfam PF13087 AAA domain 925 1099 9.3E-25 T 29-03-2018 MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 69 493 3.0E-50 T 29-03-2018 IPR019993 RecB family nuclease, TM0106, putative MSG_RS18690 3181f3c14b1eaa5a40723d4bfd57ebf9 1131 Pfam PF13604 AAA domain 751 907 3.1E-13 T 29-03-2018 MSG_RS06140 000c4f7ff5137a8a32478e3281803a39 150 Pfam PF13556 PucR C-terminal helix-turn-helix domain 87 144 2.1E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MSG_RS06140 000c4f7ff5137a8a32478e3281803a39 150 Gene3D G3DSA:1.10.10.10 54 143 9.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS00945 b49ae77be5539b693feb75705ece271e 360 SUPERFAMILY SSF53850 46 348 4.74E-63 T 29-03-2018 MSG_RS00945 b49ae77be5539b693feb75705ece271e 360 Pfam PF13531 Bacterial extracellular solute-binding protein 58 303 4.2E-39 T 29-03-2018 MSG_RS00945 b49ae77be5539b693feb75705ece271e 360 Gene3D G3DSA:3.40.190.10 44 149 3.8E-18 T 29-03-2018 MSG_RS00945 b49ae77be5539b693feb75705ece271e 360 Gene3D G3DSA:3.40.190.10 150 352 1.1E-36 T 29-03-2018 MSG_RS00945 b49ae77be5539b693feb75705ece271e 360 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 44 348 8.4E-94 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 Gene3D G3DSA:3.40.640.10 37 244 2.0E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 SUPERFAMILY SSF53383 19 346 1.36E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 350 46.281 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 Gene3D G3DSA:3.90.1150.10 245 350 8.6E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 351 44.814 T 29-03-2018 IPR024892 Putative phenylalanine aminotransferase MSG_RS23980 48078d42397a68275aef58800ffc78b7 355 Pfam PF00155 Aminotransferase class I and II 25 342 3.6E-45 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS06505 aa4ef0adcbb4822ec18f9add6826b00a 351 Pfam PF13828 Domain of unknown function (DUF4190) 67 118 3.6E-11 T 29-03-2018 IPR025241 Domain of unknown function DUF4190 MSG_RS06505 aa4ef0adcbb4822ec18f9add6826b00a 351 Pfam PF14032 PknH-like extracellular domain 153 348 5.9E-31 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS12940 a1db95860c87d28b1269d516f11213f3 137 Gene3D G3DSA:3.10.129.10 7 131 1.4E-24 T 29-03-2018 MSG_RS12940 a1db95860c87d28b1269d516f11213f3 137 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 128 6.5E-22 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MSG_RS12940 a1db95860c87d28b1269d516f11213f3 137 SUPERFAMILY SSF54637 13 131 7.07E-27 T 29-03-2018 IPR029069 HotDog domain MSG_RS12940 a1db95860c87d28b1269d516f11213f3 137 Pfam PF03061 Thioesterase superfamily 46 125 6.9E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 6.0E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 Gene3D G3DSA:3.40.50.720 4 48 3.4E-9 T 29-03-2018 MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 Gene3D G3DSA:3.40.50.720 49 256 7.9E-49 T 29-03-2018 MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.8E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 6.8E-54 T 29-03-2018 MSG_RS23690 e7311bf124bf52c4efe040688eedc296 257 SUPERFAMILY SSF51735 11 253 7.75E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS24390 65d9b461ee9eb55517d2c38f7bf0cf36 252 Pfam PF06912 Protein of unknown function (DUF1275) 23 229 2.0E-24 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 MSG_RS23635 5de22a6cea9c0a3cc19133bc62781a1d 341 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 264 2.6E-66 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain MSG_RS19525 e77692f07c943a33a3c41d7e3f0d0d79 364 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 18 277 5.8E-57 T 29-03-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 MSG_RS19525 e77692f07c943a33a3c41d7e3f0d0d79 364 SUPERFAMILY SSF51735 320 351 2.64E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19525 e77692f07c943a33a3c41d7e3f0d0d79 364 SUPERFAMILY SSF51735 16 291 2.64E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19525 e77692f07c943a33a3c41d7e3f0d0d79 364 Gene3D G3DSA:3.40.50.720 9 353 1.5E-57 T 29-03-2018 MSG_RS21680 052cfd5ab6a4bfdb3654aee3682546db 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 26 297 3.4E-79 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MSG_RS21680 052cfd5ab6a4bfdb3654aee3682546db 304 SUPERFAMILY SSF161098 35 290 3.66E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS21680 052cfd5ab6a4bfdb3654aee3682546db 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 302 3.4E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS21680 052cfd5ab6a4bfdb3654aee3682546db 304 Gene3D G3DSA:1.10.3720.10 27 304 1.3E-35 T 29-03-2018 MSG_RS22710 0f6549bc8d5e2a81c89f5c087ac9feba 328 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 38 308 2.1E-43 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MSG_RS22710 0f6549bc8d5e2a81c89f5c087ac9feba 328 Gene3D G3DSA:3.20.20.190 27 321 3.6E-70 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS22710 0f6549bc8d5e2a81c89f5c087ac9feba 328 SUPERFAMILY SSF51695 33 314 3.66E-64 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MSG_RS13120 0f033766d1de56c4b68f8232e84cc689 195 Gene3D G3DSA:3.30.1020.10 162 194 1.9E-5 T 29-03-2018 MSG_RS13120 0f033766d1de56c4b68f8232e84cc689 195 Pfam PF00578 AhpC/TSA family 6 146 2.9E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS13120 0f033766d1de56c4b68f8232e84cc689 195 PIRSF PIRSF000239 1 195 1.4E-48 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MSG_RS13120 0f033766d1de56c4b68f8232e84cc689 195 SUPERFAMILY SSF52833 4 188 3.16E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS13120 0f033766d1de56c4b68f8232e84cc689 195 Gene3D G3DSA:3.40.30.10 1 161 3.4E-38 T 29-03-2018 MSG_RS02260 f95922c3895a7a09f43cbc6112c199b1 469 Pfam PF07690 Major Facilitator Superfamily 40 407 6.6E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS02260 f95922c3895a7a09f43cbc6112c199b1 469 Gene3D G3DSA:1.20.1250.20 221 452 1.1E-16 T 29-03-2018 MSG_RS02260 f95922c3895a7a09f43cbc6112c199b1 469 Gene3D G3DSA:1.20.1250.20 22 218 3.1E-14 T 29-03-2018 MSG_RS02260 f95922c3895a7a09f43cbc6112c199b1 469 SUPERFAMILY SSF103473 24 448 9.81E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 31 126 2.6E-17 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 28 234 22.177 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 SUPERFAMILY SSF69754 30 139 2.88E-21 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 29 132 7.6E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 175 230 1.4E-23 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal MSG_RS05925 c1e0b3dc445b377b99c1bfe393842491 234 Gene3D G3DSA:3.30.160.100 27 132 2.4E-22 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MSG_RS18470 359e87f7f75cd99a86cbfa9e26b93a44 316 Pfam PF00146 NADH dehydrogenase 12 305 2.4E-39 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14695 f0d4a10e68b96d086505462e32618bbe 101 ProDom PD069409 MB2104 RV2078/MT2139 1 98 6.0E-26 T 29-03-2018 IPR022534 Protein of unknown function DUF2563 MSG_RS14695 f0d4a10e68b96d086505462e32618bbe 101 Pfam PF10817 Protein of unknown function (DUF2563) 1 100 3.3E-38 T 29-03-2018 IPR022534 Protein of unknown function DUF2563 MSG_RS14695 f0d4a10e68b96d086505462e32618bbe 101 Gene3D G3DSA:1.10.287.1060 1 98 3.1E-8 T 29-03-2018 MSG_RS16345 00ec7f55256dabc973d2ac234f17b44d 456 Pfam PF00296 Luciferase-like monooxygenase 47 404 1.3E-53 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS16345 00ec7f55256dabc973d2ac234f17b44d 456 SUPERFAMILY SSF51679 23 454 1.27E-113 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS16345 00ec7f55256dabc973d2ac234f17b44d 456 PIRSF PIRSF000337 21 456 5.0E-140 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS16345 00ec7f55256dabc973d2ac234f17b44d 456 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 27 448 1.1E-143 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MSG_RS16345 00ec7f55256dabc973d2ac234f17b44d 456 Gene3D G3DSA:3.20.20.30 16 456 7.1E-95 T 29-03-2018 MSG_RS06495 5d82a1f503f022152734a30843e48204 256 Pfam PF00106 short chain dehydrogenase 1 166 4.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS06495 5d82a1f503f022152734a30843e48204 256 Gene3D G3DSA:3.40.50.720 1 246 9.0E-40 T 29-03-2018 MSG_RS06495 5d82a1f503f022152734a30843e48204 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MSG_RS06495 5d82a1f503f022152734a30843e48204 256 SUPERFAMILY SSF51735 1 230 4.51E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07470 febe44289670a205626dfe975c6ef2d3 275 Gene3D G3DSA:3.90.79.10 6 233 2.8E-29 T 29-03-2018 MSG_RS07470 febe44289670a205626dfe975c6ef2d3 275 SUPERFAMILY SSF55811 5 59 5.9E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS07470 febe44289670a205626dfe975c6ef2d3 275 SUPERFAMILY SSF55811 87 98 5.9E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS07470 febe44289670a205626dfe975c6ef2d3 275 SUPERFAMILY SSF55811 147 210 5.9E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS01795 fb4e48d1ff1436c37588d124c99cf8b4 287 Gene3D G3DSA:1.10.10.10 2 68 6.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01795 fb4e48d1ff1436c37588d124c99cf8b4 287 SUPERFAMILY SSF46785 12 74 2.46E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS01795 fb4e48d1ff1436c37588d124c99cf8b4 287 Gene3D G3DSA:3.30.450.40 76 286 7.4E-22 T 29-03-2018 IPR029016 GAF domain-like MSG_RS01795 fb4e48d1ff1436c37588d124c99cf8b4 287 SUPERFAMILY SSF55781 65 185 3.14E-7 T 29-03-2018 IPR029016 GAF domain-like MSG_RS20885 87822689deb0b5bbf93b82356bec5436 137 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 13 43 8.3E-7 T 29-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal MSG_RS20885 87822689deb0b5bbf93b82356bec5436 137 Gene3D G3DSA:2.40.50.140 52 118 3.4E-7 T 29-03-2018 MSG_RS20885 87822689deb0b5bbf93b82356bec5436 137 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 117 1.8E-14 T 29-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal MSG_RS20885 87822689deb0b5bbf93b82356bec5436 137 SUPERFAMILY SSF50249 14 123 1.03E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS19710 f94f7755e4b5516e5efe9c1dd0779a75 293 Pfam PF13230 Glutamine amidotransferases class-II 1 255 6.9E-21 T 29-03-2018 IPR026869 Putative glutamine amidotransferase type 2 MSG_RS19710 f94f7755e4b5516e5efe9c1dd0779a75 293 Gene3D G3DSA:3.60.20.10 1 262 9.2E-37 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS19710 f94f7755e4b5516e5efe9c1dd0779a75 293 SUPERFAMILY SSF56235 2 253 7.72E-32 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 Gene3D G3DSA:1.10.630.10 2 401 7.5E-67 T 29-03-2018 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 SUPERFAMILY SSF48264 18 400 1.7E-83 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 Pfam PF00067 Cytochrome P450 275 374 1.7E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 351 362 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 158 173 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 276 287 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 293 320 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 141 157 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 94 105 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 321 336 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 195 217 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS17885 6fe2d46ee22c87bc74d6ddd6b5e55f2f 403 PRINTS PR00359 B-class P450 signature 342 351 9.7E-38 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS19365 b0b14af238d810eee346b0a78bbae1e4 413 Pfam PF06974 Protein of unknown function (DUF1298) 270 413 1.1E-4 T 29-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 259 431 5.6E-43 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 231 4.2E-24 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 487 172.041 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 SUPERFAMILY SSF52540 4 242 1.04E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 Gene3D G3DSA:3.40.50.880 252 477 2.9E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 SUPERFAMILY SSF52317 260 437 1.39E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 Gene3D G3DSA:3.40.50.300 2 241 2.0E-48 T 29-03-2018 MSG_RS08430 71b08849a428bec45f4b9bd44d02c19e 501 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 478 8.5E-134 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MSG_RS10715 3627d9702caf7acb64faa6de1557afd9 271 Gene3D G3DSA:2.40.10.10 58 160 2.1E-14 T 29-03-2018 MSG_RS10715 3627d9702caf7acb64faa6de1557afd9 271 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 201 212 - T 29-03-2018 IPR033116 Serine proteases, trypsin family, serine active site MSG_RS10715 3627d9702caf7acb64faa6de1557afd9 271 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 93 98 - T 29-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 MSG_RS10715 3627d9702caf7acb64faa6de1557afd9 271 SUPERFAMILY SSF50494 72 231 1.62E-16 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS23815 2c4f891391eead3d7f68c0264d852c51 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 206 2.7E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS23815 2c4f891391eead3d7f68c0264d852c51 247 SUPERFAMILY SSF161098 25 205 2.09E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS23815 2c4f891391eead3d7f68c0264d852c51 247 Gene3D G3DSA:1.10.3720.10 2 210 1.1E-22 T 29-03-2018 MSG_RS10480 0aa0285e99a450f7800812c5f153af30 133 Gene3D G3DSA:1.20.120.330 11 107 1.5E-8 T 29-03-2018 MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 68 307 2.7E-58 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 SUPERFAMILY SSF55315 60 142 4.71E-16 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 SMART SM00967 69 145 1.5E-14 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 Gene3D G3DSA:3.40.1280.10 142 309 1.8E-46 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 Pfam PF00588 SpoU rRNA Methylase family 161 300 2.7E-35 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 Gene3D G3DSA:3.30.1330.30 44 141 3.0E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 SUPERFAMILY SSF75217 133 308 4.77E-44 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MSG_RS22715 91ced4612a675cb147754e59e4db8ab3 309 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 70 144 1.3E-16 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MSG_RS21020 6b09d56bffcec4c6da8e7f55fc7cadf6 139 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 27 139 4.1E-29 T 29-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 MSG_RS01600 d96803f048239c79ad42f154ff6a112f 277 Pfam PF13622 Thioesterase-like superfamily 30 270 1.6E-33 T 29-03-2018 MSG_RS01600 d96803f048239c79ad42f154ff6a112f 277 SUPERFAMILY SSF54637 135 272 3.8E-12 T 29-03-2018 IPR029069 HotDog domain MSG_RS02145 f001d25d518fe39d687a247b3d85e294 68 Pfam PF11021 Protein of unknown function (DUF2613) 4 57 1.7E-6 T 29-03-2018 IPR022566 Protein of unknown function DUF2613 MSG_RS18605 983781731fd9616977ad4110d85e4e5b 275 Pfam PF03167 Uracil DNA glycosylase superfamily 96 266 5.1E-28 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18605 983781731fd9616977ad4110d85e4e5b 275 SUPERFAMILY SSF52141 63 270 4.91E-43 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18605 983781731fd9616977ad4110d85e4e5b 275 Gene3D G3DSA:3.40.470.10 52 274 1.0E-55 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18605 983781731fd9616977ad4110d85e4e5b 275 SMART SM00986 96 265 1.8E-30 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MSG_RS18605 983781731fd9616977ad4110d85e4e5b 275 SMART SM00987 96 265 1.8E-30 T 29-03-2018 MSG_RS14215 97c5eaef02384f8f59694585a97c8a41 370 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 188 1.2E-24 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS14215 97c5eaef02384f8f59694585a97c8a41 370 SUPERFAMILY SSF51735 5 306 2.09E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS14215 97c5eaef02384f8f59694585a97c8a41 370 Gene3D G3DSA:3.40.50.720 1 317 1.2E-37 T 29-03-2018 MSG_RS06445 12da871890ff5199da2e41c7a3dab4d7 142 Gene3D G3DSA:2.30.110.10 4 142 2.3E-19 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS06445 12da871890ff5199da2e41c7a3dab4d7 142 SUPERFAMILY SSF50475 7 138 7.3E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS06445 12da871890ff5199da2e41c7a3dab4d7 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 87 2.1E-8 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS21045 3da62352d2b5157de73961efa24854d8 93 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 9 82 5.5E-9 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MSG_RS06885 047734d792cd8e60dcd501daf90dca51 297 Gene3D G3DSA:1.10.357.20 4 294 0.002 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MSG_RS06885 047734d792cd8e60dcd501daf90dca51 297 Pfam PF02687 FtsX-like permease family 200 290 4.7E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MSG_RS06885 047734d792cd8e60dcd501daf90dca51 297 PIRSF PIRSF003097 1 297 5.4E-57 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 MSG_RS13470 0612257badaf13a999f73e2c900cff8d 126 Pfam PF05991 YacP-like NYN domain 4 121 1.8E-12 T 29-03-2018 IPR010298 Protein of unknown function DUF901 MSG_RS19745 945941269747465202ab67c5c5d3904f 411 Pfam PF13847 Methyltransferase domain 57 154 1.3E-13 T 29-03-2018 IPR025714 Methyltransferase domain MSG_RS19745 945941269747465202ab67c5c5d3904f 411 SUPERFAMILY SSF53335 36 164 1.14E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19745 945941269747465202ab67c5c5d3904f 411 SUPERFAMILY SSF53335 220 260 1.14E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS19745 945941269747465202ab67c5c5d3904f 411 Gene3D G3DSA:3.40.50.150 25 307 2.1E-20 T 29-03-2018 MSG_RS07500 c82bc813016f91388a8fcb27d86f69d6 359 Gene3D G3DSA:3.40.50.150 51 228 2.4E-13 T 29-03-2018 MSG_RS07500 c82bc813016f91388a8fcb27d86f69d6 359 SUPERFAMILY SSF53335 52 187 9.39E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS00165 f989f9001581b3650c5cb5d58d3f4fe6 110 Gene3D G3DSA:3.40.630.30 4 103 3.0E-19 T 29-03-2018 MSG_RS00165 f989f9001581b3650c5cb5d58d3f4fe6 110 SUPERFAMILY SSF55729 11 97 7.32E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS00165 f989f9001581b3650c5cb5d58d3f4fe6 110 Pfam PF14542 GCN5-related N-acetyl-transferase 19 95 8.5E-24 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 60 288 36.553 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 SUPERFAMILY SSF64005 56 282 7.72E-81 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 233 250 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 Gene3D G3DSA:3.40.1180.10 46 289 6.4E-82 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 Pfam PF01255 Putative undecaprenyl diphosphate synthase 67 287 9.8E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS16675 7bbb8fea9d36b80cd71618b68a3152bd 289 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 60 287 2.6E-70 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 Pfam PF07969 Amidohydrolase family 26 508 7.9E-93 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 Gene3D G3DSA:3.20.20.140 146 442 3.8E-41 T 29-03-2018 MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 SUPERFAMILY SSF51338 1 55 4.32E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 SUPERFAMILY SSF51556 36 96 7.48E-32 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 SUPERFAMILY SSF51556 162 441 7.48E-32 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS14560 6dd28ff2112190cca83dababc8d059f1 510 Gene3D G3DSA:2.30.40.10 1 87 3.8E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS00890 09fcde3e83149b1ad1b12d042dbe3016 272 Gene3D G3DSA:3.20.20.370 69 271 9.1E-34 T 29-03-2018 MSG_RS00890 09fcde3e83149b1ad1b12d042dbe3016 272 SUPERFAMILY SSF88713 70 267 2.6E-39 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS00890 09fcde3e83149b1ad1b12d042dbe3016 272 Pfam PF01522 Polysaccharide deacetylase 78 201 3.7E-23 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS16480 6ccc17a831afd79a9051a6a14bd6f15a 155 Pfam PF14041 LppP/LprE lipoprotein 59 141 5.9E-24 T 29-03-2018 IPR025971 LppP/LprE lipoprotein MSG_RS16480 6ccc17a831afd79a9051a6a14bd6f15a 155 ProDom PD091785 LIPOPROTEIN LPPP PALMITATE MEMBRANE PRECURSOR SIGNAL 3 155 2.0E-61 T 29-03-2018 IPR020217 Uncharacterised protein family, lipoprotein LppP MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 Pfam PF17384 RimP C-terminal SH3 domain 89 154 3.5E-10 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 Gene3D G3DSA:2.30.30.180 90 152 1.7E-5 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 SUPERFAMILY SSF74942 87 154 6.41E-6 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 9 154 19.414 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 Pfam PF02576 RimP N-terminal domain 20 86 1.5E-12 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 SUPERFAMILY SSF75420 9 86 5.62E-15 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MSG_RS08520 864a0ebb46d27f37ff0b361b8e5f595d 177 Gene3D G3DSA:3.30.300.70 6 83 4.3E-14 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MSG_RS16305 0f1dd6b24b6b315ff5639bf4907342ad 300 Gene3D G3DSA:1.20.5.100 161 200 3.2E-4 T 29-03-2018 MSG_RS16305 0f1dd6b24b6b315ff5639bf4907342ad 300 Pfam PF04536 TPM domain 37 154 9.5E-20 T 29-03-2018 IPR007621 TPM domain MSG_RS16405 3a9ba1292d07712e57ad8b3cd4f5e5e3 294 Gene3D G3DSA:1.10.3720.10 15 292 3.7E-46 T 29-03-2018 MSG_RS16405 3a9ba1292d07712e57ad8b3cd4f5e5e3 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 287 7.9E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16405 3a9ba1292d07712e57ad8b3cd4f5e5e3 294 SUPERFAMILY SSF161098 57 279 1.83E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS04720 2b397731e98f1103d993bb0cea7721f4 166 Pfam PF01047 MarR family 58 114 4.3E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS04720 2b397731e98f1103d993bb0cea7721f4 166 Gene3D G3DSA:1.10.10.10 2 165 8.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04720 2b397731e98f1103d993bb0cea7721f4 166 SUPERFAMILY SSF46785 31 163 7.66E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04720 2b397731e98f1103d993bb0cea7721f4 166 SMART SM00347 48 149 1.2E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 PRINTS PR00723 Subtilisin serine protease family (S8) signature 436 452 2.4E-10 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 PRINTS PR00723 Subtilisin serine protease family (S8) signature 136 149 2.4E-10 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 PRINTS PR00723 Subtilisin serine protease family (S8) signature 101 120 2.4E-10 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 Gene3D G3DSA:3.40.50.200 74 495 1.6E-61 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 Pfam PF00082 Subtilase family 244 486 1.3E-20 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 SUPERFAMILY SSF52743 240 494 1.67E-44 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 SUPERFAMILY SSF52743 86 154 1.67E-44 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24595 1b3ae9b9f682b8bd22ed3813685ff625 554 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 240 549 2.0E-84 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 PRINTS PR01438 Universal stress protein signature 156 174 6.3E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 PRINTS PR01438 Universal stress protein signature 272 294 6.3E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 PRINTS PR01438 Universal stress protein signature 254 266 6.3E-16 T 29-03-2018 IPR006015 Universal stress protein A MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 Pfam PF00582 Universal stress protein family 158 294 4.8E-23 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 Pfam PF00582 Universal stress protein family 9 145 1.3E-20 T 29-03-2018 IPR006016 UspA GO:0006950 MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 SUPERFAMILY SSF52402 9 147 5.78E-24 T 29-03-2018 MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 Gene3D G3DSA:3.40.50.620 2 151 4.1E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 SUPERFAMILY SSF52402 158 297 5.61E-30 T 29-03-2018 MSG_RS06980 5249a0932cf0c225051b7470bc461b33 306 Gene3D G3DSA:3.40.50.620 157 294 4.2E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MSG_RS11030 794c3710c76df0cb30500c2ba1447462 409 Gene3D G3DSA:3.40.710.10 19 394 5.9E-74 T 29-03-2018 MSG_RS11030 794c3710c76df0cb30500c2ba1447462 409 SUPERFAMILY SSF56601 271 381 6.02E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS11030 794c3710c76df0cb30500c2ba1447462 409 SUPERFAMILY SSF56601 19 230 6.02E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS11030 794c3710c76df0cb30500c2ba1447462 409 Pfam PF00144 Beta-lactamase 24 389 1.8E-63 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS15005 6937ca09a5a44a1f84a76e6ff4de9c65 352 Gene3D G3DSA:1.10.10.10 46 239 4.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS15005 6937ca09a5a44a1f84a76e6ff4de9c65 352 SUPERFAMILY SSF46785 142 198 9.73E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19505 b238510455245e76c33e37c39f067167 335 Pfam PF02401 LytB protein 25 302 3.6E-89 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MSG_RS19505 b238510455245e76c33e37c39f067167 335 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 25 304 3.1E-97 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MSG_RS19505 b238510455245e76c33e37c39f067167 335 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 23 306 36.676 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MSG_RS23515 a79e8cf34df7ce780d0ec6f372e1e8f5 486 Pfam PF00324 Amino acid permease 26 460 1.5E-93 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MSG_RS23515 a79e8cf34df7ce780d0ec6f372e1e8f5 486 PIRSF PIRSF006060 4 475 5.7E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS23515 a79e8cf34df7ce780d0ec6f372e1e8f5 486 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MSG_RS20770 7c038ea17ca7e15bcc492cbf83e82012 162 Pfam PF10969 Protein of unknown function (DUF2771) 6 159 2.4E-53 T 29-03-2018 IPR024495 Protein of unknown function DUF2771 MSG_RS20770 7c038ea17ca7e15bcc492cbf83e82012 162 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 29 162 1.0E-61 T 29-03-2018 IPR024495 Protein of unknown function DUF2771 MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 SUPERFAMILY SSF53850 49 253 5.59E-50 T 29-03-2018 MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 SMART SM00062 32 243 0.0014 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 34 301 1.1E-69 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 Pfam PF09084 NMT1/THI5 like 54 246 1.0E-24 T 29-03-2018 IPR015168 SsuA/THI5-like MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 Gene3D G3DSA:3.40.190.10 28 122 3.2E-10 T 29-03-2018 MSG_RS00625 8ff9cf4fc838ca3b9aec4bff4ce220ac 321 Gene3D G3DSA:3.40.190.10 123 251 5.8E-32 T 29-03-2018 MSG_RS18890 7566049843ba58e6fa58add785c03ebb 683 Gene3D G3DSA:1.25.40.10 382 618 2.7E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS18890 7566049843ba58e6fa58add785c03ebb 683 Gene3D G3DSA:3.40.50.300 1 43 9.0E-5 T 29-03-2018 MSG_RS18890 7566049843ba58e6fa58add785c03ebb 683 SUPERFAMILY SSF52540 2 119 8.04E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18890 7566049843ba58e6fa58add785c03ebb 683 Gene3D G3DSA:1.25.40.10 53 377 5.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS09830 33607475649fff9a14b4f2b949ea652b 336 SUPERFAMILY SSF53474 40 334 2.42E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09830 33607475649fff9a14b4f2b949ea652b 336 Pfam PF07859 alpha/beta hydrolase fold 103 312 1.7E-57 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS09830 33607475649fff9a14b4f2b949ea652b 336 Gene3D G3DSA:3.40.50.1820 16 336 4.2E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24465 6f51d0b8b796dcd22853cb307829b40a 104 Gene3D G3DSA:1.10.287.1060 1 99 1.4E-7 T 29-03-2018 MSG_RS24465 6f51d0b8b796dcd22853cb307829b40a 104 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 3 99 5.8E-22 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 MSG_RS09860 a2f37855a4d3a2b0614ab8b9065a61d0 355 PRINTS PR01217 Proline rich extensin signature 80 97 2.3E-9 T 29-03-2018 MSG_RS09860 a2f37855a4d3a2b0614ab8b9065a61d0 355 PRINTS PR01217 Proline rich extensin signature 58 74 2.3E-9 T 29-03-2018 MSG_RS09860 a2f37855a4d3a2b0614ab8b9065a61d0 355 PRINTS PR01217 Proline rich extensin signature 34 55 2.3E-9 T 29-03-2018 MSG_RS09860 a2f37855a4d3a2b0614ab8b9065a61d0 355 PRINTS PR01217 Proline rich extensin signature 19 31 2.3E-9 T 29-03-2018 MSG_RS00330 7bc672c4fa201bbf63a77d713774c127 141 Pfam PF17249 Family of unknown function (DUF5318) 1 123 3.7E-64 T 29-03-2018 IPR035169 Protein of unknown function DUF5318 MSG_RS16930 1b502458180dac120e17bc3c4a099668 282 Pfam PF12706 Beta-lactamase superfamily domain 32 241 6.9E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16930 1b502458180dac120e17bc3c4a099668 282 SMART SM00849 19 218 3.8E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16930 1b502458180dac120e17bc3c4a099668 282 SUPERFAMILY SSF56281 3 275 1.28E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16930 1b502458180dac120e17bc3c4a099668 282 Gene3D G3DSA:3.60.15.10 2 282 2.1E-50 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS16930 1b502458180dac120e17bc3c4a099668 282 Hamap MF_01818 Ribonuclease BN [rbn]. 2 276 23.169 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MSG_RS07935 598c2256c7c43facd2711f092b4339f4 243 Pfam PF11139 Sap, sulfolipid-1-addressing protein 2 209 9.7E-42 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS09430 784f1fd70ce986c24878b07fa28b7742 388 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 305 384 8.2E-16 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS09430 784f1fd70ce986c24878b07fa28b7742 388 Pfam PF00823 PPE family 5 161 6.8E-61 T 29-03-2018 IPR000030 PPE family MSG_RS09430 784f1fd70ce986c24878b07fa28b7742 388 SUPERFAMILY SSF140459 3 173 3.92E-62 T 29-03-2018 MSG_RS09430 784f1fd70ce986c24878b07fa28b7742 388 Gene3D G3DSA:1.10.287.1060 21 100 3.3E-4 T 29-03-2018 MSG_RS16840 257e9858d5bcf5aad66b16f4c53ebfd7 412 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 16 403 8.0E-108 T 29-03-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily MSG_RS16840 257e9858d5bcf5aad66b16f4c53ebfd7 412 Gene3D G3DSA:1.20.1250.20 67 400 3.3E-6 T 29-03-2018 MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 PRINTS PR00069 Aldo-keto reductase signature 54 78 4.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 PRINTS PR00069 Aldo-keto reductase signature 149 166 4.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 PRINTS PR00069 Aldo-keto reductase signature 118 136 4.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 PRINTS PR00069 Aldo-keto reductase signature 220 244 4.4E-8 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 Gene3D G3DSA:3.20.20.100 14 289 1.5E-75 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 Pfam PF00248 Aldo/keto reductase family 24 285 2.9E-61 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS09565 9ad1ee0a346061eb4f2f9eec4384e762 289 SUPERFAMILY SSF51430 14 285 2.62E-78 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 Pfam PF00005 ABC transporter 21 151 1.8E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 Pfam PF00005 ABC transporter 302 438 2.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 SMART SM00382 29 207 9.6E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 SMART SM00382 311 490 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 SUPERFAMILY SSF52540 11 201 4.1E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 SUPERFAMILY SSF52540 277 486 1.12E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 Gene3D G3DSA:3.40.50.300 2 236 9.0E-43 T 29-03-2018 MSG_RS11565 1da7db373a420e2a5ae960a3fe37b4e9 591 Gene3D G3DSA:3.40.50.300 264 517 5.0E-48 T 29-03-2018 MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 PIRSF PIRSF002122 4 156 2.7E-57 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.3E-62 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 SUPERFAMILY SSF47973 1 149 5.36E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 Gene3D G3DSA:1.10.455.10 6 156 9.9E-58 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.4E-68 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04285 a53082ab313f5e6a1755952358d0180f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.807 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MSG_RS16420 c5fecbe5ee74ca67ad4b6e020fc8bc46 474 Pfam PF13520 Amino acid permease 35 441 2.9E-50 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS16420 c5fecbe5ee74ca67ad4b6e020fc8bc46 474 PIRSF PIRSF006060 23 473 7.7E-84 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 Pfam PF16884 N-terminal domain of oxidoreductase 6 108 6.5E-37 T 29-03-2018 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 SMART SM00829 19 333 2.8E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 SUPERFAMILY SSF50129 5 145 1.91E-32 T 29-03-2018 IPR011032 GroES-like MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 Gene3D G3DSA:3.90.180.10 1 150 5.4E-38 T 29-03-2018 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 Gene3D G3DSA:3.40.50.720 151 277 6.8E-26 T 29-03-2018 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 Pfam PF00107 Zinc-binding dehydrogenase 160 293 2.8E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MSG_RS13530 7ec590fc5722c731156deb5011e4775e 336 SUPERFAMILY SSF51735 124 301 1.35E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 SMART SM00387 510 625 6.9E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 SMART SM00304 331 398 0.0018 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 Gene3D G3DSA:3.30.565.10 431 624 8.3E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 SUPERFAMILY SSF55874 499 624 1.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 515 623 2.8E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS05265 8de9108e61fbb15497a58834254b14e0 898 Pfam PF00672 HAMP domain 331 392 4.1E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MSG_RS08510 cfcd51d5cea2dcda1be70b26377d8911 162 Pfam PF14530 Domain of unknown function (DUF4439) 25 161 9.5E-42 T 29-03-2018 IPR029447 Domain of unknown function DUF4439 MSG_RS08510 cfcd51d5cea2dcda1be70b26377d8911 162 Gene3D G3DSA:1.20.1260.10 17 151 8.2E-17 T 29-03-2018 IPR012347 Ferritin-related MSG_RS08510 cfcd51d5cea2dcda1be70b26377d8911 162 SUPERFAMILY SSF47240 19 158 9.12E-43 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS14620 a9c3b34f3f42b098f6453db8d0f7232d 90 Pfam PF13490 Putative zinc-finger 9 43 3.9E-9 T 29-03-2018 IPR027383 Putative zinc-finger MSG_RS06550 53065a9ced3f4d6573952860d4beebca 314 Gene3D G3DSA:2.40.110.10 73 163 1.7E-10 T 29-03-2018 MSG_RS06550 53065a9ced3f4d6573952860d4beebca 314 SUPERFAMILY SSF56645 5 167 2.75E-15 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 SUPERFAMILY SSF53901 272 393 1.35E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 Pfam PF00108 Thiolase, N-terminal domain 10 263 2.1E-60 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 392 6.1E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 Gene3D G3DSA:3.40.47.10 6 264 7.5E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 Pfam PF02803 Thiolase, C-terminal domain 272 393 1.4E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 PIRSF PIRSF000429 4 395 8.1E-122 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 SUPERFAMILY SSF53901 7 269 5.97E-67 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS06050 b2ad0f85ebda752856e592325200f2a5 395 Gene3D G3DSA:3.40.47.10 265 391 4.6E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS22785 e89b95fc77157bb878d35b2a17ff6086 183 SUPERFAMILY SSF53254 6 182 6.64E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS22785 e89b95fc77157bb878d35b2a17ff6086 183 SMART SM00855 6 147 1.1E-14 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS22785 e89b95fc77157bb878d35b2a17ff6086 183 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 182 3.6E-25 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MSG_RS22785 e89b95fc77157bb878d35b2a17ff6086 183 Gene3D G3DSA:3.40.50.1240 2 183 2.7E-24 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MSG_RS01550 c2f1fe14a03b95559b89b42d826ccb8c 105 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 93 2.3E-31 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MSG_RS04470 42c97835b81b77fb2b7c7165d37ae51a 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 80 95 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04470 42c97835b81b77fb2b7c7165d37ae51a 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 21.559 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MSG_RS04470 42c97835b81b77fb2b7c7165d37ae51a 100 Gene3D G3DSA:3.30.70.330 5 99 4.3E-31 T 29-03-2018 MSG_RS04470 42c97835b81b77fb2b7c7165d37ae51a 100 SUPERFAMILY SSF54189 5 95 1.26E-32 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MSG_RS04470 42c97835b81b77fb2b7c7165d37ae51a 100 Pfam PF00276 Ribosomal protein L23 9 91 5.2E-31 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MSG_RS08850 2c89b36b5e2b1564d6cfe9d70f918bb7 112 Gene3D G3DSA:1.10.260.40 2 79 7.8E-16 T 29-03-2018 MSG_RS08850 2c89b36b5e2b1564d6cfe9d70f918bb7 112 SUPERFAMILY SSF47413 5 71 1.24E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MSG_RS08850 2c89b36b5e2b1564d6cfe9d70f918bb7 112 Pfam PF13560 Helix-turn-helix domain 9 63 7.1E-14 T 29-03-2018 MSG_RS08850 2c89b36b5e2b1564d6cfe9d70f918bb7 112 SMART SM00530 12 67 3.3E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MSG_RS13975 e22443313aca45df73fd2a6eae948240 92 Gene3D G3DSA:1.10.1200.10 1 84 1.7E-10 T 29-03-2018 MSG_RS13975 e22443313aca45df73fd2a6eae948240 92 SUPERFAMILY SSF47336 5 87 1.31E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS13975 e22443313aca45df73fd2a6eae948240 92 Pfam PF00550 Phosphopantetheine attachment site 22 77 3.3E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MSG_RS08450 d95c60a0819fdbdaa0859aebc5ee6213 377 Pfam PF03824 High-affinity nickel-transport protein 69 361 5.9E-91 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MSG_RS08450 d95c60a0819fdbdaa0859aebc5ee6213 377 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 71 356 1.4E-121 T 29-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 SUPERFAMILY SSF56601 368 735 6.04E-90 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 SUPERFAMILY SSF56601 314 336 6.04E-90 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 Pfam PF00905 Penicillin binding protein transpeptidase domain 426 689 5.7E-30 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 Pfam PF00912 Transglycosylase 157 332 5.1E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 Gene3D G3DSA:3.40.710.10 351 735 9.4E-89 T 29-03-2018 MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 Gene3D G3DSA:1.10.3810.10 144 347 1.8E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MSG_RS00335 5cd213538c41170acd1161b67a5dbbf7 809 SUPERFAMILY SSF53955 140 350 4.22E-62 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS22030 1d615ba83dee962d5b865c667f4c6bb5 67 SUPERFAMILY SSF54862 4 63 2.44E-12 T 29-03-2018 MSG_RS22030 1d615ba83dee962d5b865c667f4c6bb5 67 Pfam PF13459 4Fe-4S single cluster domain 5 63 4.0E-13 T 29-03-2018 MSG_RS22030 1d615ba83dee962d5b865c667f4c6bb5 67 Gene3D G3DSA:3.30.70.20 2 66 6.8E-8 T 29-03-2018 MSG_RS07390 07558be061adee2507fa6e9cd4d96f50 181 Gene3D G3DSA:1.10.10.60 47 136 2.5E-8 T 29-03-2018 MSG_RS07390 07558be061adee2507fa6e9cd4d96f50 181 Gene3D G3DSA:1.10.10.60 2 46 2.6E-15 T 29-03-2018 MSG_RS07390 07558be061adee2507fa6e9cd4d96f50 181 SUPERFAMILY SSF46689 3 73 1.54E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS07390 07558be061adee2507fa6e9cd4d96f50 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS17795 2d43a569c15c1b2da77fa5dd05222c9d 388 Pfam PF04909 Amidohydrolase 22 371 2.5E-34 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS17795 2d43a569c15c1b2da77fa5dd05222c9d 388 Gene3D G3DSA:3.20.20.140 10 371 2.5E-41 T 29-03-2018 MSG_RS17795 2d43a569c15c1b2da77fa5dd05222c9d 388 SUPERFAMILY SSF51556 20 49 4.77E-52 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS17795 2d43a569c15c1b2da77fa5dd05222c9d 388 SUPERFAMILY SSF51556 80 371 4.77E-52 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS05340 c1fde71ed8f63a8b02362a9a416f8ce6 621 Pfam PF13520 Amino acid permease 30 430 1.1E-16 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS18735 c662eaf40024fc2ccb78417a601cea95 193 Pfam PF05076 Suppressor of fused protein (SUFU) 25 188 3.9E-33 T 29-03-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 MSG_RS00980 98383a25d38bc47e652855218dcf0fec 468 SUPERFAMILY SSF103378 6 448 2.62E-89 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS00980 98383a25d38bc47e652855218dcf0fec 468 Gene3D G3DSA:1.10.4100.10 2 308 2.0E-64 T 29-03-2018 MSG_RS00980 98383a25d38bc47e652855218dcf0fec 468 Pfam PF03972 MmgE/PrpD family 8 437 2.0E-105 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS10530 4b7fb7dee0233723023bdd5683ac972b 230 Gene3D G3DSA:3.30.420.40 114 220 2.9E-4 T 29-03-2018 MSG_RS02840 d58281f0b2001fa3f1d2daa2144623b1 287 SUPERFAMILY SSF54427 175 282 3.15E-5 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS02840 d58281f0b2001fa3f1d2daa2144623b1 287 Gene3D G3DSA:3.10.450.50 170 284 2.8E-5 T 29-03-2018 MSG_RS19440 3133c2d320dc27e6c5974df2b0723f20 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.4E-16 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MSG_RS19440 3133c2d320dc27e6c5974df2b0723f20 107 Gene3D G3DSA:3.30.70.100 1 98 1.3E-17 T 29-03-2018 MSG_RS19440 3133c2d320dc27e6c5974df2b0723f20 107 SUPERFAMILY SSF54909 1 96 1.36E-24 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS01145 6b564daf4d09194d3087257ce39afc15 395 Gene3D G3DSA:3.40.50.10540 1 377 1.7E-117 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS01145 6b564daf4d09194d3087257ce39afc15 395 SUPERFAMILY SSF89796 1 373 3.53E-114 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS01145 6b564daf4d09194d3087257ce39afc15 395 Pfam PF02515 CoA-transferase family III 1 364 4.4E-112 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS03955 3c36a68f9d027fed46803ab007a93d08 380 Gene3D G3DSA:2.102.10.10 21 126 4.1E-23 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS03955 3c36a68f9d027fed46803ab007a93d08 380 SUPERFAMILY SSF55961 123 342 7.97E-29 T 29-03-2018 MSG_RS03955 3c36a68f9d027fed46803ab007a93d08 380 Pfam PF00355 Rieske [2Fe-2S] domain 24 110 5.9E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS03955 3c36a68f9d027fed46803ab007a93d08 380 Gene3D G3DSA:3.90.380.10 127 347 2.1E-33 T 29-03-2018 MSG_RS03955 3c36a68f9d027fed46803ab007a93d08 380 SUPERFAMILY SSF50022 16 132 1.05E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS16415 6070302ddd929423f18c3bc463ffcaf4 445 Pfam PF01547 Bacterial extracellular solute-binding protein 51 356 7.5E-38 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 MSG_RS16415 6070302ddd929423f18c3bc463ffcaf4 445 Gene3D G3DSA:3.40.190.10 169 445 1.6E-29 T 29-03-2018 MSG_RS16415 6070302ddd929423f18c3bc463ffcaf4 445 SUPERFAMILY SSF53850 46 440 5.38E-53 T 29-03-2018 MSG_RS16415 6070302ddd929423f18c3bc463ffcaf4 445 Gene3D G3DSA:3.40.190.10 40 168 1.6E-22 T 29-03-2018 MSG_RS19195 2e0ff8f40fef001b4d40e3bbe724ad7d 121 SUPERFAMILY SSF46785 10 84 1.87E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19195 2e0ff8f40fef001b4d40e3bbe724ad7d 121 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 80 2.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS19195 2e0ff8f40fef001b4d40e3bbe724ad7d 121 Gene3D G3DSA:1.10.10.10 3 94 6.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS19195 2e0ff8f40fef001b4d40e3bbe724ad7d 121 SMART SM00345 21 80 3.4E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MSG_RS04425 7f0922772d8d4b823b7b1a48e456f092 71 Gene3D G3DSA:3.30.920.30 2 62 1.3E-8 T 29-03-2018 MSG_RS10920 ae504fd6a62d63c6771365876f8c752d 197 SUPERFAMILY SSF69118 12 178 4.2E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS10920 ae504fd6a62d63c6771365876f8c752d 197 Gene3D G3DSA:1.20.1290.10 11 182 9.4E-31 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS10920 ae504fd6a62d63c6771365876f8c752d 197 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 123 3.7E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS11980 96e4fc6997441194915c369296c6a440 292 Pfam PF00990 Diguanylate cyclase, GGDEF domain 153 286 4.3E-28 T 29-03-2018 IPR000160 GGDEF domain MSG_RS11980 96e4fc6997441194915c369296c6a440 292 SUPERFAMILY SSF55073 158 286 2.12E-31 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS11980 96e4fc6997441194915c369296c6a440 292 Gene3D G3DSA:3.30.70.270 136 290 3.5E-38 T 29-03-2018 MSG_RS11980 96e4fc6997441194915c369296c6a440 292 SMART SM00267 142 291 4.3E-29 T 29-03-2018 IPR000160 GGDEF domain MSG_RS11980 96e4fc6997441194915c369296c6a440 292 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 151 286 8.5E-27 T 29-03-2018 IPR000160 GGDEF domain MSG_RS07495 2f1e3f0469894308f2d5da8d75a1e17e 320 SUPERFAMILY SSF53335 217 319 1.81E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07495 2f1e3f0469894308f2d5da8d75a1e17e 320 SUPERFAMILY SSF53335 34 184 1.81E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS07495 2f1e3f0469894308f2d5da8d75a1e17e 320 Pfam PF08241 Methyltransferase domain 75 172 1.1E-22 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS07495 2f1e3f0469894308f2d5da8d75a1e17e 320 Gene3D G3DSA:3.40.50.150 19 276 3.4E-34 T 29-03-2018 MSG_RS16310 a414d41601f9b9bedc05c189e0f5497d 178 Gene3D G3DSA:2.60.40.1240 33 176 1.0E-4 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain MSG_RS05125 001443128cc14d744bc9c07db6e73abb 578 Gene3D G3DSA:3.50.50.60 1 549 1.9E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05125 001443128cc14d744bc9c07db6e73abb 578 Pfam PF05199 GMC oxidoreductase 468 525 1.4E-11 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MSG_RS05125 001443128cc14d744bc9c07db6e73abb 578 Pfam PF01266 FAD dependent oxidoreductase 6 299 3.2E-10 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MSG_RS05125 001443128cc14d744bc9c07db6e73abb 578 SUPERFAMILY SSF51905 470 531 4.92E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05125 001443128cc14d744bc9c07db6e73abb 578 SUPERFAMILY SSF51905 1 300 4.92E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS12740 3f70f5a231cd902730defb52eb3cb4ff 107 Pfam PF05305 Protein of unknown function (DUF732) 3 97 4.7E-25 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS07055 a119b7a8b796ce1260083a8f56b0b1ab 188 Gene3D G3DSA:1.20.120.520 6 168 2.1E-16 T 29-03-2018 MSG_RS07055 a119b7a8b796ce1260083a8f56b0b1ab 188 Pfam PF01814 Hemerythrin HHE cation binding domain 13 128 4.5E-10 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MSG_RS04415 f59fe8e3f415b41633a272bcceda565c 71 SUPERFAMILY SSF46689 19 67 1.27E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS04415 f59fe8e3f415b41633a272bcceda565c 71 Gene3D G3DSA:1.10.10.10 15 71 3.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS04415 f59fe8e3f415b41633a272bcceda565c 71 Pfam PF01527 Transposase 17 70 1.3E-7 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MSG_RS09635 28609b6cb7f71e5cb6d93c6113730e8f 531 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 311 324 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MSG_RS09635 28609b6cb7f71e5cb6d93c6113730e8f 531 Gene3D G3DSA:3.40.50.150 286 510 1.3E-41 T 29-03-2018 MSG_RS09635 28609b6cb7f71e5cb6d93c6113730e8f 531 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 233 513 23.277 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MSG_RS09635 28609b6cb7f71e5cb6d93c6113730e8f 531 SUPERFAMILY SSF53335 233 505 3.48E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS09635 28609b6cb7f71e5cb6d93c6113730e8f 531 Pfam PF01564 Spermine/spermidine synthase domain 307 468 3.7E-30 T 29-03-2018 MSG_RS13350 1ef2b07201cb7edcb8199c81e2b79c5d 326 Pfam PF03060 Nitronate monooxygenase 80 308 3.9E-31 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS13350 1ef2b07201cb7edcb8199c81e2b79c5d 326 Pfam PF03060 Nitronate monooxygenase 3 56 4.0E-10 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS13350 1ef2b07201cb7edcb8199c81e2b79c5d 326 SUPERFAMILY SSF51412 1 310 2.59E-51 T 29-03-2018 MSG_RS13350 1ef2b07201cb7edcb8199c81e2b79c5d 326 Gene3D G3DSA:3.20.20.70 1 319 3.1E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS15905 2bb6f41760f52cd698182bb9cfec3200 291 Pfam PF00775 Dioxygenase 103 287 5.7E-44 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MSG_RS15905 2bb6f41760f52cd698182bb9cfec3200 291 Pfam PF04444 Catechol dioxygenase N terminus 23 91 1.5E-25 T 29-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 MSG_RS15905 2bb6f41760f52cd698182bb9cfec3200 291 SUPERFAMILY SSF49482 3 288 6.02E-87 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MSG_RS15905 2bb6f41760f52cd698182bb9cfec3200 291 Gene3D G3DSA:2.60.130.10 1 290 3.5E-82 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 Gene3D G3DSA:1.20.1640.10 502 719 4.4E-26 T 29-03-2018 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 PRINTS PR00702 Acriflavin resistance protein family signature 205 226 3.8E-6 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 PRINTS PR00702 Acriflavin resistance protein family signature 311 334 3.8E-6 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 Pfam PF03176 MMPL family 45 374 1.8E-39 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 Pfam PF03176 MMPL family 410 731 1.6E-34 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 SUPERFAMILY SSF82866 505 721 5.49E-25 T 29-03-2018 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 SUPERFAMILY SSF82866 118 340 3.66E-27 T 29-03-2018 MSG_RS07105 c51c85c913a13b8e0d752c9c4a2712e2 735 Gene3D G3DSA:1.20.1640.10 133 351 3.7E-29 T 29-03-2018 MSG_RS21665 cd2fc8ca3c5679b790404558a07f5204 709 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 280 453 1.8E-46 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS21665 cd2fc8ca3c5679b790404558a07f5204 709 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 582 666 1.1E-14 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS21665 cd2fc8ca3c5679b790404558a07f5204 709 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 279 454 5.2E-60 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS11420 223daa2fb44d0a856735c0a38f80b304 291 Pfam PF01936 NYN domain 8 174 7.8E-24 T 29-03-2018 IPR021139 NYN domain, limkain-b1-type MSG_RS11420 223daa2fb44d0a856735c0a38f80b304 291 Pfam PF12872 OST-HTH/LOTUS domain 221 281 2.3E-10 T 29-03-2018 IPR025605 OST-HTH/LOTUS domain MSG_RS11420 223daa2fb44d0a856735c0a38f80b304 291 Gene3D G3DSA:3.40.50.1010 1 177 3.3E-33 T 29-03-2018 IPR029060 PIN domain-like MSG_RS21300 b664cb75082f854bc5b30da745847273 432 SUPERFAMILY SSF51556 67 383 4.99E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21300 b664cb75082f854bc5b30da745847273 432 SUPERFAMILY SSF51556 7 36 4.99E-79 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS21300 b664cb75082f854bc5b30da745847273 432 Pfam PF04909 Amidohydrolase 81 374 1.2E-35 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS21300 b664cb75082f854bc5b30da745847273 432 Gene3D G3DSA:3.20.20.140 1 378 2.7E-68 T 29-03-2018 MSG_RS07705 92abf79b3fc45090d8f2b6abb09bd3ca 218 SUPERFAMILY SSF55021 3 71 8.33E-6 T 29-03-2018 MSG_RS07705 92abf79b3fc45090d8f2b6abb09bd3ca 218 Gene3D G3DSA:3.30.70.260 2 94 3.1E-6 T 29-03-2018 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 Pfam PF00005 ABC transporter 352 503 1.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 Gene3D G3DSA:1.20.1560.10 2 317 7.9E-69 T 29-03-2018 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 SUPERFAMILY SSF52540 328 574 7.31E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 SMART SM00382 361 550 2.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 SUPERFAMILY SSF90123 6 316 8.11E-66 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 Pfam PF00664 ABC transporter transmembrane region 20 288 7.6E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MSG_RS18545 72916a9eb01946afa9a8608f7998e3a4 582 Gene3D G3DSA:3.40.50.300 325 579 1.3E-65 T 29-03-2018 MSG_RS11475 f3d4ebe7e90a4b3bb6aafd8050dd97d6 301 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 129 279 1.4E-11 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS11475 f3d4ebe7e90a4b3bb6aafd8050dd97d6 301 SMART SM00044 84 286 1.8E-24 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS11475 f3d4ebe7e90a4b3bb6aafd8050dd97d6 301 SUPERFAMILY SSF55073 126 269 2.67E-35 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS11475 f3d4ebe7e90a4b3bb6aafd8050dd97d6 301 Gene3D G3DSA:3.30.70.1230 116 289 3.4E-26 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS14935 b9c34504c481c7b5ceab5e70d983003d 331 Gene3D G3DSA:2.130.10.10 43 331 4.5E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MSG_RS14935 b9c34504c481c7b5ceab5e70d983003d 331 SUPERFAMILY SSF63829 90 327 1.24E-22 T 29-03-2018 MSG_RS09675 05b2199a457497febf60752aa53aca3b 128 Pfam PF06993 Protein of unknown function (DUF1304) 10 122 1.3E-34 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 MSG_RS19160 307c8779e00f92034af0c1f7b0e41c29 195 Gene3D G3DSA:1.10.340.30 18 143 5.0E-12 T 29-03-2018 MSG_RS19160 307c8779e00f92034af0c1f7b0e41c29 195 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 188 1.3E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MSG_RS19160 307c8779e00f92034af0c1f7b0e41c29 195 SUPERFAMILY SSF48150 13 146 1.36E-12 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MSG_RS19160 307c8779e00f92034af0c1f7b0e41c29 195 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 5 195 1.7E-96 T 29-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD MSG_RS05755 0990c23e3ea730e070bd13c90d4ccf68 396 Gene3D G3DSA:3.40.50.10540 8 395 5.6E-106 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS05755 0990c23e3ea730e070bd13c90d4ccf68 396 SUPERFAMILY SSF89796 12 393 1.44E-106 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS05755 0990c23e3ea730e070bd13c90d4ccf68 396 Pfam PF02515 CoA-transferase family III 14 392 4.4E-114 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS20750 9f4cca68308954d86afc07f66c398417 91 Pfam PF10745 Protein of unknown function (DUF2530) 10 84 5.3E-26 T 29-03-2018 IPR019681 Protein of unknown function DUF2530 MSG_RS09050 20b7a8fe9217613d446c6cfa6f4c874e 217 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 91 180 3.3E-13 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 309 336 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 337 352 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 368 379 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 110 121 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 213 235 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 173 188 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 292 303 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 156 172 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 PRINTS PR00359 B-class P450 signature 359 368 2.2E-43 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 Pfam PF00067 Cytochrome P450 295 383 1.1E-12 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 Gene3D G3DSA:1.10.630.10 2 419 1.2E-59 T 29-03-2018 MSG_RS13230 5d19ae964be8a5cfcbd5bb55f4c531d5 423 SUPERFAMILY SSF48264 11 414 2.75E-79 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS16160 26f6ad787f01b0f0ea878b91ca171d5d 280 Gene3D G3DSA:3.10.129.10 10 123 1.8E-5 T 29-03-2018 MSG_RS16160 26f6ad787f01b0f0ea878b91ca171d5d 280 Pfam PF13622 Thioesterase-like superfamily 37 260 4.3E-17 T 29-03-2018 MSG_RS16220 765eaa010300483d8def00eba18b217e 476 Gene3D G3DSA:3.30.559.10 23 225 1.1E-7 T 29-03-2018 MSG_RS16220 765eaa010300483d8def00eba18b217e 476 SUPERFAMILY SSF52777 64 216 1.78E-15 T 29-03-2018 MSG_RS16220 765eaa010300483d8def00eba18b217e 476 SUPERFAMILY SSF52777 229 462 2.11E-20 T 29-03-2018 MSG_RS16220 765eaa010300483d8def00eba18b217e 476 Pfam PF00668 Condensation domain 69 368 5.6E-17 T 29-03-2018 IPR001242 Condensation domain MSG_RS11125 145443074e00f1036524f3949f4e2a2f 239 Pfam PF00293 NUDIX domain 36 136 4.1E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS11125 145443074e00f1036524f3949f4e2a2f 239 SUPERFAMILY SSF46785 156 228 2.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11125 145443074e00f1036524f3949f4e2a2f 239 Gene3D G3DSA:1.10.10.10 163 232 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11125 145443074e00f1036524f3949f4e2a2f 239 Gene3D G3DSA:3.90.79.10 20 162 3.7E-25 T 29-03-2018 MSG_RS11125 145443074e00f1036524f3949f4e2a2f 239 SUPERFAMILY SSF55811 32 152 5.82E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 ProSitePatterns PS00450 Aconitase family signature 1. 460 476 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Gene3D G3DSA:3.30.499.10 19 228 1.1E-72 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Pfam PF00694 Aconitase C-terminal domain 724 854 7.9E-42 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 ProSitePatterns PS01244 Aconitase family signature 2. 526 539 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 139 152 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 206 221 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 361 375 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 163 171 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 464 475 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 192 205 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 282 295 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 268 281 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 PRINTS PR00415 Aconitase family signature 526 539 2.6E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 SUPERFAMILY SSF53732 434 660 1.44E-223 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 SUPERFAMILY SSF53732 2 395 1.44E-223 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Gene3D G3DSA:3.30.499.10 361 609 6.9E-68 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Gene3D G3DSA:3.20.19.10 686 934 3.3E-89 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Pfam PF00330 Aconitase family (aconitate hydratase) 62 595 1.8E-176 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 SUPERFAMILY SSF52016 664 933 2.94E-81 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MSG_RS10635 dd80d4bb2dc8f61edf30a4a2d02741cd 936 Gene3D G3DSA:3.40.1060.10 229 360 7.7E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MSG_RS19295 6e9c34a8b7ef637269643ba25002a4e6 213 Gene3D G3DSA:3.40.50.720 2 213 4.4E-29 T 29-03-2018 MSG_RS19295 6e9c34a8b7ef637269643ba25002a4e6 213 Pfam PF13460 NAD(P)H-binding 8 189 3.8E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS19295 6e9c34a8b7ef637269643ba25002a4e6 213 SUPERFAMILY SSF51735 3 202 1.19E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS13955 725bea519dec9193804cf53c4768c315 129 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 111 4.5E-15 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS13955 725bea519dec9193804cf53c4768c315 129 Gene3D G3DSA:2.30.110.10 5 123 2.3E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13955 725bea519dec9193804cf53c4768c315 129 Pfam PF04075 F420H(2)-dependent quinone reductase 32 96 1.4E-5 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS07440 eddc7d1bac49b3184bf4248f7898f1dc 123 Pfam PF11829 Protein of unknown function (DUF3349) 1 90 1.7E-25 T 29-03-2018 IPR021784 Protein of unknown function DUF3349 MSG_RS06945 1c301e14b66255ae326a7809c326a942 124 SMART SM00448 6 119 3.5E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS06945 1c301e14b66255ae326a7809c326a942 124 SUPERFAMILY SSF52172 6 119 2.28E-24 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS06945 1c301e14b66255ae326a7809c326a942 124 Gene3D G3DSA:3.40.50.2300 1 124 7.2E-25 T 29-03-2018 MSG_RS06945 1c301e14b66255ae326a7809c326a942 124 Pfam PF00072 Response regulator receiver domain 8 117 2.7E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 Pfam PF00571 CBS domain 77 127 1.4E-9 T 29-03-2018 IPR000644 CBS domain MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 Pfam PF00571 CBS domain 18 66 0.0032 T 29-03-2018 IPR000644 CBS domain MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 SMART SM00116 83 130 0.21 T 29-03-2018 IPR000644 CBS domain MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 SMART SM00116 19 66 8.9 T 29-03-2018 IPR000644 CBS domain MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 SUPERFAMILY SSF54631 12 131 2.78E-21 T 29-03-2018 MSG_RS05605 c6f52e868b898f1bb8706228e913dce0 141 Gene3D G3DSA:3.10.580.10 10 131 1.2E-18 T 29-03-2018 MSG_RS21835 60802e946bc13d2686e832cac059bc28 266 Pfam PF04454 Encapsulating protein for peroxidase 3 252 2.9E-95 T 29-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 MSG_RS21835 60802e946bc13d2686e832cac059bc28 266 PIRSF PIRSF019254 1 266 8.5E-94 T 29-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 Pfam PF00561 alpha/beta hydrolase fold 61 261 2.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 Gene3D G3DSA:3.30.70.1230 273 444 6.0E-26 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 SUPERFAMILY SSF55073 284 444 7.22E-36 T 29-03-2018 IPR029787 Nucleotide cyclase MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 Gene3D G3DSA:3.40.50.1820 3 272 2.8E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 SUPERFAMILY SSF53474 7 270 4.1E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 3.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 3.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 3.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 3.7E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 290 440 5.0E-7 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS02600 8f196e5a7349ccf94e00595b8df45425 451 SMART SM00044 232 424 0.002 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MSG_RS20670 c0dc51806629f349183ed97536573c84 119 Pfam PF04972 BON domain 68 105 9.0E-4 T 29-03-2018 IPR007055 BON domain MSG_RS21370 83c0b4c9d25b69a73fae49f907065023 138 Pfam PF17240 Family of unknown function (DUF5313) 5 126 2.1E-52 T 29-03-2018 IPR035197 Protein of unknown function DUF5313 MSG_RS22330 96f549fc4f75f3ed25ccfce2e6885141 274 SUPERFAMILY SSF51556 11 270 2.04E-59 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS22330 96f549fc4f75f3ed25ccfce2e6885141 274 Gene3D G3DSA:3.20.20.140 3 273 8.3E-45 T 29-03-2018 MSG_RS22330 96f549fc4f75f3ed25ccfce2e6885141 274 Pfam PF04909 Amidohydrolase 35 270 2.2E-38 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 SUPERFAMILY SSF48498 79 181 7.11E-21 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 SUPERFAMILY SSF46689 4 63 1.44E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 Gene3D G3DSA:1.10.357.10 60 184 1.2E-17 T 29-03-2018 MSG_RS00560 89122a9a4be01c75269e3c0476863159 185 Gene3D G3DSA:1.10.10.60 1 59 3.1E-19 T 29-03-2018 MSG_RS09520 03c6ee00c733c1b73446f0fe4cc1cc73 269 Pfam PF01522 Polysaccharide deacetylase 68 190 9.7E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS09520 03c6ee00c733c1b73446f0fe4cc1cc73 269 SUPERFAMILY SSF88713 61 257 1.63E-37 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS09520 03c6ee00c733c1b73446f0fe4cc1cc73 269 Gene3D G3DSA:3.20.20.370 55 264 8.9E-30 T 29-03-2018 MSG_RS10290 80875dcc4f532ff346dece8c6f377f1d 285 Pfam PF00296 Luciferase-like monooxygenase 20 250 7.7E-35 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS10290 80875dcc4f532ff346dece8c6f377f1d 285 Gene3D G3DSA:3.20.20.30 12 285 1.1E-50 T 29-03-2018 MSG_RS10290 80875dcc4f532ff346dece8c6f377f1d 285 SUPERFAMILY SSF51679 16 282 1.02E-45 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS12310 f94e7f3b94db9dc5bb9125454c1dea0b 147 Gene3D G3DSA:3.10.129.10 4 147 9.7E-32 T 29-03-2018 MSG_RS12310 f94e7f3b94db9dc5bb9125454c1dea0b 147 SUPERFAMILY SSF54637 2 139 5.83E-24 T 29-03-2018 IPR029069 HotDog domain MSG_RS12310 f94e7f3b94db9dc5bb9125454c1dea0b 147 Pfam PF01575 MaoC like domain 16 111 8.2E-5 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS23220 fda9a98e917639ae8df00460bcc78446 121 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 108 6.4E-20 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MSG_RS23220 fda9a98e917639ae8df00460bcc78446 121 SUPERFAMILY SSF52091 11 115 9.61E-21 T 29-03-2018 IPR002645 STAS domain MSG_RS23220 fda9a98e917639ae8df00460bcc78446 121 Pfam PF01740 STAS domain 12 110 3.3E-14 T 29-03-2018 IPR002645 STAS domain MSG_RS23220 fda9a98e917639ae8df00460bcc78446 121 Gene3D G3DSA:3.30.750.24 3 121 1.7E-22 T 29-03-2018 IPR002645 STAS domain MSG_RS20410 32c0de08cbdc6962e777cf5b58841fe0 301 Gene3D G3DSA:1.10.620.20 8 262 8.5E-29 T 29-03-2018 MSG_RS20410 32c0de08cbdc6962e777cf5b58841fe0 301 SUPERFAMILY SSF47240 33 226 4.54E-11 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS20410 32c0de08cbdc6962e777cf5b58841fe0 301 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 10 285 6.2E-99 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF MSG_RS20930 73a9fd6bb2dc5d2b31dcb076cd932bde 207 SUPERFAMILY SSF53335 11 181 1.03E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS20930 73a9fd6bb2dc5d2b31dcb076cd932bde 207 Pfam PF13649 Methyltransferase domain 47 138 8.2E-17 T 29-03-2018 MSG_RS20930 73a9fd6bb2dc5d2b31dcb076cd932bde 207 Gene3D G3DSA:3.40.50.150 18 206 2.1E-27 T 29-03-2018 MSG_RS03280 5269963aa93bbe6fee4e4631bb08a59d 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 2.9E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS03280 5269963aa93bbe6fee4e4631bb08a59d 226 Gene3D G3DSA:1.10.357.10 17 219 7.2E-23 T 29-03-2018 MSG_RS03280 5269963aa93bbe6fee4e4631bb08a59d 226 SUPERFAMILY SSF46689 16 86 5.64E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19720 3269122c12591e579dfc5adb770d204d 381 Gene3D G3DSA:2.130.10.10 17 86 4.4E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MSG_RS19720 3269122c12591e579dfc5adb770d204d 381 Gene3D G3DSA:2.130.10.10 228 376 7.7E-17 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MSG_RS19720 3269122c12591e579dfc5adb770d204d 381 Gene3D G3DSA:2.130.10.10 87 216 3.2E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MSG_RS19720 3269122c12591e579dfc5adb770d204d 381 SUPERFAMILY SSF51004 24 372 3.14E-38 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MSG_RS02140 0d59f3c26d57fa42ecd9da0d00f4164b 57 Pfam PF11021 Protein of unknown function (DUF2613) 3 56 1.5E-22 T 29-03-2018 IPR022566 Protein of unknown function DUF2613 MSG_RS02140 0d59f3c26d57fa42ecd9da0d00f4164b 57 ProDom PD383784 PRECURSOR SIGNAL SECRETED MB0242C RV0236.1/MT0250 ML2569.1 3 56 3.0E-17 T 29-03-2018 MSG_RS17770 83c5bbff7875c290a72b2f8b29d476b0 401 Pfam PF04909 Amidohydrolase 99 384 2.8E-26 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS17770 83c5bbff7875c290a72b2f8b29d476b0 401 Gene3D G3DSA:3.20.20.140 3 394 1.3E-60 T 29-03-2018 MSG_RS17770 83c5bbff7875c290a72b2f8b29d476b0 401 SUPERFAMILY SSF51556 8 37 8.81E-67 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS17770 83c5bbff7875c290a72b2f8b29d476b0 401 SUPERFAMILY SSF51556 91 390 8.81E-67 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS10800 3cec526d32093ada5c835ae39236d904 298 Pfam PF13489 Methyltransferase domain 95 233 2.2E-17 T 29-03-2018 MSG_RS10800 3cec526d32093ada5c835ae39236d904 298 Gene3D G3DSA:3.40.50.150 86 250 8.0E-17 T 29-03-2018 MSG_RS10800 3cec526d32093ada5c835ae39236d904 298 SUPERFAMILY SSF53335 91 274 8.2E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS23860 a67f19934b7ca6ee2dbabbc440640c84 351 SUPERFAMILY SSF56112 7 300 1.46E-47 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS23860 a67f19934b7ca6ee2dbabbc440640c84 351 Gene3D G3DSA:3.90.1200.10 115 298 2.0E-21 T 29-03-2018 MSG_RS23860 a67f19934b7ca6ee2dbabbc440640c84 351 Gene3D G3DSA:3.30.200.20 8 110 8.6E-16 T 29-03-2018 MSG_RS23860 a67f19934b7ca6ee2dbabbc440640c84 351 Pfam PF01636 Phosphotransferase enzyme family 32 258 7.9E-29 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS09365 87829d80d49223838701651b6be302fc 287 Pfam PF05065 Phage capsid family 12 284 1.5E-37 T 29-03-2018 IPR024455 Phage capsid MSG_RS09365 87829d80d49223838701651b6be302fc 287 SUPERFAMILY SSF56563 1 285 1.44E-42 T 29-03-2018 MSG_RS09365 87829d80d49223838701651b6be302fc 287 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 1 284 2.4E-41 T 29-03-2018 IPR024455 Phage capsid MSG_RS09365 87829d80d49223838701651b6be302fc 287 Gene3D G3DSA:3.30.2320.10 155 252 1.2E-16 T 29-03-2018 MSG_RS09365 87829d80d49223838701651b6be302fc 287 Gene3D G3DSA:3.30.2400.10 34 154 2.6E-20 T 29-03-2018 MSG_RS23010 f25007a7cc8aa3e79073d23a8ab122d4 101 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 1 97 4.3E-21 T 29-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like MSG_RS23010 f25007a7cc8aa3e79073d23a8ab122d4 101 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 1 38 2.0E-6 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal MSG_RS03400 90b13c273fcd373a4a4edbabd7fca730 200 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 2 159 9.0E-52 T 29-03-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 MSG_RS03400 90b13c273fcd373a4a4edbabd7fca730 200 Gene3D G3DSA:1.20.120.20 16 180 9.0E-7 T 29-03-2018 MSG_RS03400 90b13c273fcd373a4a4edbabd7fca730 200 SUPERFAMILY SSF58113 26 102 5.89E-5 T 29-03-2018 MSG_RS16410 33a51190e4640cdb88884e9b887a57bb 274 SUPERFAMILY SSF161098 5 274 7.85E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16410 33a51190e4640cdb88884e9b887a57bb 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 266 2.3E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16410 33a51190e4640cdb88884e9b887a57bb 274 Gene3D G3DSA:1.10.3720.10 4 262 2.0E-37 T 29-03-2018 MSG_RS00595 17a28d9ad2f3a26ba663e0db9dcfe5d4 356 Gene3D G3DSA:3.20.20.30 1 348 3.2E-74 T 29-03-2018 MSG_RS00595 17a28d9ad2f3a26ba663e0db9dcfe5d4 356 SUPERFAMILY SSF51679 1 339 1.7E-70 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS00595 17a28d9ad2f3a26ba663e0db9dcfe5d4 356 Pfam PF00296 Luciferase-like monooxygenase 1 304 1.6E-61 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS12805 32950edc35e9efef65bc043c9421d559 307 Pfam PF05949 Bacterial protein of unknown function (DUF881) 149 303 4.5E-32 T 29-03-2018 IPR010273 Protein of unknown function DUF881 MSG_RS17060 1a7c3273109ea045c8d52fe56d7d88f5 476 SUPERFAMILY SSF103378 14 461 1.29E-108 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS17060 1a7c3273109ea045c8d52fe56d7d88f5 476 Gene3D G3DSA:1.10.4100.10 1 323 7.2E-85 T 29-03-2018 MSG_RS17060 1a7c3273109ea045c8d52fe56d7d88f5 476 Pfam PF03972 MmgE/PrpD family 16 450 3.9E-116 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MSG_RS16905 44965b131d3378fd97ed9d6d53fd6c24 687 Pfam PF00723 Glycosyl hydrolases family 15 299 612 7.0E-51 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 MSG_RS16905 44965b131d3378fd97ed9d6d53fd6c24 687 SUPERFAMILY SSF48208 270 667 2.27E-97 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 MSG_RS16905 44965b131d3378fd97ed9d6d53fd6c24 687 Gene3D G3DSA:1.50.10.10 280 624 4.6E-91 T 29-03-2018 MSG_RS02060 0a2de269363ac56f8fe559afd91bdc36 421 Pfam PF11271 Protein of unknown function (DUF3068) 6 338 1.1E-93 T 29-03-2018 IPR021424 Porin PorA MSG_RS06120 1d7425207272620b12c559c950283487 473 Gene3D G3DSA:3.50.50.60 1 472 2.7E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06120 1d7425207272620b12c559c950283487 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 58 9.4E-11 T 29-03-2018 MSG_RS06120 1d7425207272620b12c559c950283487 473 SUPERFAMILY SSF51905 3 301 1.79E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS06120 1d7425207272620b12c559c950283487 473 SUPERFAMILY SSF51905 433 462 1.79E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 Gene3D G3DSA:3.20.20.60 14 583 2.2E-143 T 29-03-2018 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 ProSitePatterns PS00161 Isocitrate lyase signature. 213 218 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 SUPERFAMILY SSF51621 426 600 1.73E-113 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 SUPERFAMILY SSF51621 14 275 1.73E-113 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 Pfam PF00463 Isocitrate lyase family 22 284 1.7E-71 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS13390 aecd01bf87a3a5078fbaa8ff5be7204c 766 Pfam PF00463 Isocitrate lyase family 360 599 2.3E-47 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MSG_RS17420 acdd4f9bce915a42e3d087200dad371c 124 SUPERFAMILY SSF54427 1 117 3.76E-13 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS17420 acdd4f9bce915a42e3d087200dad371c 124 Gene3D G3DSA:3.10.450.50 1 124 4.3E-12 T 29-03-2018 MSG_RS17420 acdd4f9bce915a42e3d087200dad371c 124 Pfam PF12680 SnoaL-like domain 16 113 2.3E-9 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS15925 937adaf0e5d3b794bd53994ee6d6acd2 150 ProSitePatterns PS00934 Glyoxalase I signature 1. 10 31 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MSG_RS15925 937adaf0e5d3b794bd53994ee6d6acd2 150 SUPERFAMILY SSF54593 8 139 1.18E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS15925 937adaf0e5d3b794bd53994ee6d6acd2 150 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 137 4.8E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS15925 937adaf0e5d3b794bd53994ee6d6acd2 150 Gene3D G3DSA:3.10.180.10 2 141 2.1E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS06730 13f6a1012de6570305f627297ac30e15 427 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 221 234 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06730 13f6a1012de6570305f627297ac30e15 427 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 344 24.354 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06730 13f6a1012de6570305f627297ac30e15 427 Pfam PF00146 NADH dehydrogenase 19 337 2.8E-123 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06730 13f6a1012de6570305f627297ac30e15 427 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 57 72 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS01685 104d1e63e1fe4a1d75550e9f863cf9d1 310 Gene3D G3DSA:3.40.50.1820 4 308 3.8E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01685 104d1e63e1fe4a1d75550e9f863cf9d1 310 SUPERFAMILY SSF53474 67 304 3.3E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01685 104d1e63e1fe4a1d75550e9f863cf9d1 310 Pfam PF07859 alpha/beta hydrolase fold 81 283 3.3E-60 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS15745 e10f1c3bc0bf0b647af34c98e6251f6d 477 SUPERFAMILY SSF52096 14 209 6.49E-46 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS15745 e10f1c3bc0bf0b647af34c98e6251f6d 477 SUPERFAMILY SSF52096 184 462 6.53E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS15745 e10f1c3bc0bf0b647af34c98e6251f6d 477 Gene3D G3DSA:3.90.226.10 221 473 3.1E-61 T 29-03-2018 MSG_RS15745 e10f1c3bc0bf0b647af34c98e6251f6d 477 Pfam PF01039 Carboxyl transferase domain 38 463 7.9E-125 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MSG_RS15745 e10f1c3bc0bf0b647af34c98e6251f6d 477 Gene3D G3DSA:3.90.226.10 3 220 7.4E-40 T 29-03-2018 MSG_RS18235 9f6e204e0242f8c643ffc001bf20b7e0 147 Pfam PF10739 Protein of unknown function (DUF2550) 11 139 2.0E-41 T 29-03-2018 IPR019675 Protein of unknown function DUF2550 MSG_RS14770 672b0b22778f69f453ea589c67732375 201 PIRSF PIRSF021573 1 200 2.1E-83 T 29-03-2018 IPR016792 Uncharacterised conserved protein UCP021573 MSG_RS14420 af0250b05f0ad13ffb3bc59a9c0a76f1 318 SUPERFAMILY SSF88713 1 296 3.89E-81 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS14420 af0250b05f0ad13ffb3bc59a9c0a76f1 318 Gene3D G3DSA:3.20.20.370 1 300 1.5E-54 T 29-03-2018 MSG_RS14420 af0250b05f0ad13ffb3bc59a9c0a76f1 318 Pfam PF01522 Polysaccharide deacetylase 67 154 1.6E-10 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS14420 af0250b05f0ad13ffb3bc59a9c0a76f1 318 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 1 296 2.1E-147 T 29-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 MSG_RS10900 e39570bea5ae039d3dea41415b56d8b9 76 SMART SM00923 4 54 4.3E-36 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS10900 e39570bea5ae039d3dea41415b56d8b9 76 Pfam PF03621 MbtH-like protein 4 54 1.7E-30 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS10900 e39570bea5ae039d3dea41415b56d8b9 76 Gene3D G3DSA:3.90.820.10 3 69 3.9E-37 T 29-03-2018 MSG_RS10900 e39570bea5ae039d3dea41415b56d8b9 76 SUPERFAMILY SSF160582 3 70 1.57E-32 T 29-03-2018 MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 10 126 1.6E-32 T 29-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 SUPERFAMILY SSF51197 8 280 8.24E-72 T 29-03-2018 MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 Gene3D G3DSA:2.60.120.330 2 301 6.2E-78 T 29-03-2018 IPR027443 Isopenicillin N synthase-like MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 PRINTS PR00682 Isopenicillin N synthase signature 260 278 1.8E-8 T 29-03-2018 MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 PRINTS PR00682 Isopenicillin N synthase signature 148 164 1.8E-8 T 29-03-2018 MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 PRINTS PR00682 Isopenicillin N synthase signature 26 43 1.8E-8 T 29-03-2018 MSG_RS02185 eef18c361119f9cd16d29ba7df4920c2 341 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 188 272 4.8E-17 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MSG_RS23740 a3175d5050ab6d2d1a0ab8374c824f50 161 SUPERFAMILY SSF54593 8 153 3.8E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23740 a3175d5050ab6d2d1a0ab8374c824f50 161 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 126 1.8E-16 T 29-03-2018 MSG_RS23740 a3175d5050ab6d2d1a0ab8374c824f50 161 Gene3D G3DSA:3.10.180.10 1 142 3.0E-15 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.6E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 PIRSF PIRSF002599 1 67 1.6E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 SMART SM00357 3 67 4.4E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 SUPERFAMILY SSF50249 1 65 6.0E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS22995 dc6359d232d38aa1411487f9eeb6f8a4 67 Gene3D G3DSA:2.40.50.140 1 67 5.8E-29 T 29-03-2018 MSG_RS07030 b08d636cfae8a10d0a27ccb9ecf8318e 213 Pfam PF05305 Protein of unknown function (DUF732) 125 206 6.4E-16 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS02325 d8219018fc8c46fe8f4c52a4de932b4d 193 Gene3D G3DSA:3.10.180.10 9 190 2.0E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS02325 d8219018fc8c46fe8f4c52a4de932b4d 193 SUPERFAMILY SSF54593 13 180 4.7E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS02325 d8219018fc8c46fe8f4c52a4de932b4d 193 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 163 1.4E-21 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS13720 e159194f98cc252baf0b9ca61a31cf4e 272 Gene3D G3DSA:3.90.1720.10 101 271 7.9E-14 T 29-03-2018 MSG_RS13720 e159194f98cc252baf0b9ca61a31cf4e 272 Pfam PF00877 NlpC/P60 family 159 245 1.4E-10 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MSG_RS13720 e159194f98cc252baf0b9ca61a31cf4e 272 SUPERFAMILY SSF54001 163 271 2.55E-12 T 29-03-2018 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 Hamap MF_01393 ATP synthase subunit a [atpB]. 15 248 13.68 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 Gene3D G3DSA:1.20.120.220 84 250 1.1E-37 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 PRINTS PR00123 ATP synthase A subunit signature 181 203 1.4E-19 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 PRINTS PR00123 ATP synthase A subunit signature 92 108 1.4E-19 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 PRINTS PR00123 ATP synthase A subunit signature 228 243 1.4E-19 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 PRINTS PR00123 ATP synthase A subunit signature 165 180 1.4E-19 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 SUPERFAMILY SSF81336 87 242 1.57E-35 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 ProSitePatterns PS00449 ATP synthase a subunit signature. 184 193 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 Pfam PF00119 ATP synthase A chain 33 242 4.1E-48 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS18275 5ec997a8915c85bf91a56c1da0e2d410 252 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 244 1.4E-37 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MSG_RS04270 a2c6940662eac141135ab8d1d11b39d9 122 Pfam PF11259 Protein of unknown function (DUF3060) 52 110 7.6E-22 T 29-03-2018 IPR021417 Protein of unknown function DUF3060 MSG_RS14365 0f59a0aebe636a06193a5d044473214f 534 Pfam PF03239 Iron permease FTR1 family 9 264 1.7E-42 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 214 2.5E-5 T 29-03-2018 MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.7E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 Gene3D G3DSA:3.40.50.720 53 261 2.1E-52 T 29-03-2018 MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 Gene3D G3DSA:3.40.50.720 6 52 2.2E-11 T 29-03-2018 MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 252 2.0E-52 T 29-03-2018 MSG_RS10055 2d2dfed515cb2c465f22d518100a0704 274 SUPERFAMILY SSF51735 12 252 2.21E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS11680 edd502e1476f5ac56ff5f76a915f4d73 277 Gene3D G3DSA:1.25.40.10 144 270 4.7E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11680 edd502e1476f5ac56ff5f76a915f4d73 277 SUPERFAMILY SSF48452 103 262 1.71E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS11680 edd502e1476f5ac56ff5f76a915f4d73 277 Gene3D G3DSA:1.25.40.10 68 143 0.0072 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS07665 236100b0d10a5b5eefee527d8ea08002 211 Pfam PF14032 PknH-like extracellular domain 43 197 1.3E-12 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS01345 df593aa5cfac372acc73805fc03f4b2d 411 Gene3D G3DSA:3.40.50.300 97 391 2.7E-26 T 29-03-2018 MSG_RS01345 df593aa5cfac372acc73805fc03f4b2d 411 Pfam PF13469 Sulfotransferase family 115 363 1.2E-32 T 29-03-2018 MSG_RS01345 df593aa5cfac372acc73805fc03f4b2d 411 SUPERFAMILY SSF52540 106 188 1.2E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01345 df593aa5cfac372acc73805fc03f4b2d 411 SUPERFAMILY SSF52540 237 382 1.2E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06135 ff8ca4154e4f6eb49668e047d3d24b07 195 Pfam PF03729 Short repeat of unknown function (DUF308) 26 96 1.7E-11 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS06135 ff8ca4154e4f6eb49668e047d3d24b07 195 Pfam PF03729 Short repeat of unknown function (DUF308) 139 189 5.8E-7 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS06135 ff8ca4154e4f6eb49668e047d3d24b07 195 Pfam PF03729 Short repeat of unknown function (DUF308) 83 153 5.7E-9 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 4.6E-64 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 203 1.6E-69 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 11 210 32.65 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 SUPERFAMILY SSF52166 4 203 8.5E-72 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 Gene3D G3DSA:3.40.1370.10 145 204 1.6E-11 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MSG_RS04465 ee47b28677f0256fc298b9af06eb75fe 222 Gene3D G3DSA:3.40.1370.10 4 144 1.0E-51 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MSG_RS21170 916fa3f6bbdc6499b26fe1d178ffed4e 238 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 30 236 3.1E-59 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 MSG_RS21170 916fa3f6bbdc6499b26fe1d178ffed4e 238 Pfam PF03006 Haemolysin-III related 28 230 4.1E-40 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MSG_RS23225 af50bee84100818512e321c614d1b650 299 SUPERFAMILY SSF52091 173 282 3.14E-19 T 29-03-2018 IPR002645 STAS domain MSG_RS23225 af50bee84100818512e321c614d1b650 299 Gene3D G3DSA:3.30.750.24 169 290 1.9E-15 T 29-03-2018 IPR002645 STAS domain MSG_RS23225 af50bee84100818512e321c614d1b650 299 Pfam PF01740 STAS domain 175 266 1.5E-10 T 29-03-2018 IPR002645 STAS domain MSG_RS14575 7d2639adcef903621e9c5e65a5986f11 285 SUPERFAMILY SSF52317 81 219 1.78E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS14575 7d2639adcef903621e9c5e65a5986f11 285 SUPERFAMILY SSF52317 255 284 1.78E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS14575 7d2639adcef903621e9c5e65a5986f11 285 SUPERFAMILY SSF52317 3 51 1.78E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS14575 7d2639adcef903621e9c5e65a5986f11 285 Pfam PF17124 ThiJ/PfpI family-like 9 201 1.6E-21 T 29-03-2018 IPR032633 ThiJ/PfpI family-like MSG_RS14575 7d2639adcef903621e9c5e65a5986f11 285 Gene3D G3DSA:3.40.50.880 4 285 1.5E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS10850 6ee44c9f7d1925f19d9cbebeed1b20a7 328 Pfam PF00535 Glycosyl transferase family 2 21 154 4.1E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MSG_RS10850 6ee44c9f7d1925f19d9cbebeed1b20a7 328 SUPERFAMILY SSF53448 18 252 6.47E-45 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS10850 6ee44c9f7d1925f19d9cbebeed1b20a7 328 Gene3D G3DSA:3.90.550.10 3 263 5.0E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS07585 67158c6e0330ff4f6b02691dc59aab97 107 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 5 94 1.2E-20 T 29-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 Pfam PF02515 CoA-transferase family III 617 704 9.8E-13 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 Pfam PF02515 CoA-transferase family III 358 608 3.2E-65 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 Pfam PF02515 CoA-transferase family III 5 343 3.2E-68 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 SUPERFAMILY SSF89796 355 727 3.66E-88 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 Gene3D G3DSA:3.40.50.10540 353 732 8.7E-97 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 Gene3D G3DSA:3.40.50.10540 1 352 1.8E-72 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS18930 324d4036f397f16f1c3cdfc1189b67bc 734 SUPERFAMILY SSF89796 2 351 1.57E-72 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS22150 89138c560b81140bc97ccc23a385ec82 296 Gene3D G3DSA:1.10.530.10 135 265 1.1E-22 T 29-03-2018 MSG_RS22150 89138c560b81140bc97ccc23a385ec82 296 SUPERFAMILY SSF53955 119 250 2.25E-23 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS22150 89138c560b81140bc97ccc23a385ec82 296 Pfam PF01464 Transglycosylase SLT domain 149 239 3.2E-6 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MSG_RS11970 43e3d49129670b2bde73185a4dd0f1ed 71 Pfam PF05305 Protein of unknown function (DUF732) 1 66 7.2E-11 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS24470 b71c4406335da6a3393cea131f8b76e6 291 Pfam PF14011 EspG family 22 258 1.1E-46 T 29-03-2018 IPR025734 EspG family MSG_RS12610 6b8ec9c0d58f31baae01843aabbf3245 142 SUPERFAMILY SSF55961 6 140 5.79E-17 T 29-03-2018 MSG_RS12610 6b8ec9c0d58f31baae01843aabbf3245 142 Gene3D G3DSA:3.30.530.20 3 141 5.6E-14 T 29-03-2018 IPR023393 START-like domain MSG_RS12610 6b8ec9c0d58f31baae01843aabbf3245 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 140 1.7E-17 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 Pfam PF12697 Alpha/beta hydrolase family 24 267 5.4E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 Gene3D G3DSA:3.40.50.1820 1 272 7.8E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS00875 7cc0348bf7aa825a36e6c5286967e065 276 SUPERFAMILY SSF53474 1 269 6.95E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04525 3f09fef86bd1c6edea86de5c9481fba4 299 Pfam PF14494 Domain of unknown function (DUF4436) 52 296 5.9E-95 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS21065 f99796c2bc5fe10efe06971f6410c019 200 SUPERFAMILY SSF46689 17 92 2.67E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21065 f99796c2bc5fe10efe06971f6410c019 200 Gene3D G3DSA:1.10.357.10 13 200 4.9E-29 T 29-03-2018 MSG_RS21065 f99796c2bc5fe10efe06971f6410c019 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21065 f99796c2bc5fe10efe06971f6410c019 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21065 f99796c2bc5fe10efe06971f6410c019 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS05940 049e898b7ff81a43f8cbc873907e0d21 160 Gene3D G3DSA:3.30.70.1450 86 160 8.3E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS05940 049e898b7ff81a43f8cbc873907e0d21 160 PIRSF PIRSF005028 1 160 5.2E-59 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT MSG_RS05940 049e898b7ff81a43f8cbc873907e0d21 160 SUPERFAMILY SSF116726 86 157 2.22E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS05940 049e898b7ff81a43f8cbc873907e0d21 160 Pfam PF02080 TrkA-C domain 90 157 2.5E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MSG_RS18435 0b54ab835384327e42107978e806b55d 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 133 5.0E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS18435 0b54ab835384327e42107978e806b55d 137 Gene3D G3DSA:3.10.180.10 2 136 2.3E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS18435 0b54ab835384327e42107978e806b55d 137 SUPERFAMILY SSF54593 6 136 6.44E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS23230 1feaf6f16c3c316d3110e383d4e6eb76 129 SUPERFAMILY SSF52091 1 113 3.34E-17 T 29-03-2018 IPR002645 STAS domain MSG_RS23230 1feaf6f16c3c316d3110e383d4e6eb76 129 Pfam PF01740 STAS domain 8 101 8.1E-12 T 29-03-2018 IPR002645 STAS domain MSG_RS23230 1feaf6f16c3c316d3110e383d4e6eb76 129 Gene3D G3DSA:3.30.750.24 1 120 2.6E-15 T 29-03-2018 IPR002645 STAS domain MSG_RS09650 d9aac45894aa9b2adf45bef1bb846cd7 167 Pfam PF10936 Protein of unknown function DUF2617 4 165 7.0E-53 T 29-03-2018 IPR024486 Protein of unknown function DUF2617 MSG_RS09650 d9aac45894aa9b2adf45bef1bb846cd7 167 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 3 161 6.0E-37 T 29-03-2018 IPR024486 Protein of unknown function DUF2617 MSG_RS02655 ff34877c362e2beb016bd5e57ef55f69 429 SUPERFAMILY SSF53383 28 424 3.09E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS02655 ff34877c362e2beb016bd5e57ef55f69 429 Gene3D G3DSA:3.40.640.10 77 305 2.4E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS02655 ff34877c362e2beb016bd5e57ef55f69 429 Pfam PF00155 Aminotransferase class I and II 60 405 6.6E-47 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS02655 ff34877c362e2beb016bd5e57ef55f69 429 Gene3D G3DSA:3.90.1150.10 306 429 5.2E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS13030 3f06d9b14720b4ee24bc14afc249456d 241 PIRSF PIRSF026622 6 241 5.8E-111 T 29-03-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type MSG_RS13030 3f06d9b14720b4ee24bc14afc249456d 241 Pfam PF02517 CAAX protease self-immunity 115 227 7.2E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MSG_RS03150 6fd03f1ea3ea798ad8de73007ed6df1a 214 SUPERFAMILY SSF88697 6 199 1.49E-37 T 29-03-2018 IPR015947 PUA-like domain MSG_RS03150 6fd03f1ea3ea798ad8de73007ed6df1a 214 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 195 1.0E-18 T 29-03-2018 IPR003111 Lon, substrate-binding domain MSG_RS03150 6fd03f1ea3ea798ad8de73007ed6df1a 214 SMART SM00464 6 203 3.4E-31 T 29-03-2018 IPR003111 Lon, substrate-binding domain MSG_RS03150 6fd03f1ea3ea798ad8de73007ed6df1a 214 Gene3D G3DSA:2.30.130.40 4 113 2.6E-24 T 29-03-2018 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 SUPERFAMILY SSF53720 7 526 3.27E-118 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 Gene3D G3DSA:3.40.605.10 36 311 5.6E-62 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 Pfam PF00171 Aldehyde dehydrogenase family 53 523 3.3E-92 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 540 4.9E-263 T 29-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 MSG_RS18990 e8e9868050de364af539e1a9a60134a3 543 Gene3D G3DSA:3.40.309.10 312 504 4.3E-43 T 29-03-2018 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 11 120 28.835 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 SUPERFAMILY SSF54843 11 120 6.28E-41 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 Gene3D G3DSA:3.90.470.10 2 174 9.0E-49 T 29-03-2018 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 ProSitePatterns PS00464 Ribosomal protein L22 signature. 93 117 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 15 117 2.9E-50 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MSG_RS04485 861d20d3e5e47315dc0604c3c75fee1c 184 Pfam PF00237 Ribosomal protein L22p/L17e 15 117 1.0E-35 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MSG_RS14105 877e6b27360a7f1b7602bb47dcae7e4c 374 Gene3D G3DSA:3.30.1330.30 252 364 6.0E-9 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MSG_RS14105 877e6b27360a7f1b7602bb47dcae7e4c 374 Gene3D G3DSA:3.30.420.60 117 247 1.2E-16 T 29-03-2018 MSG_RS12935 909bb46cc772154e201100d43b677d1a 138 SUPERFAMILY SSF46785 4 123 9.09E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12935 909bb46cc772154e201100d43b677d1a 138 Pfam PF03965 Penicillinase repressor 7 120 7.4E-30 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MSG_RS12935 909bb46cc772154e201100d43b677d1a 138 Gene3D G3DSA:1.10.10.10 8 71 8.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS12935 909bb46cc772154e201100d43b677d1a 138 PIRSF PIRSF019455 1 131 7.8E-22 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MSG_RS23510 5610ec02fa9ef31c35e3fdccb232107b 247 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 28 127 4.0E-20 T 29-03-2018 IPR013559 YheO-like MSG_RS23510 5610ec02fa9ef31c35e3fdccb232107b 247 Gene3D G3DSA:1.10.10.60 197 240 7.3E-5 T 29-03-2018 MSG_RS23510 5610ec02fa9ef31c35e3fdccb232107b 247 Gene3D G3DSA:1.10.357.10 17 196 8.4E-4 T 29-03-2018 MSG_RS23510 5610ec02fa9ef31c35e3fdccb232107b 247 Pfam PF13309 HTH domain 179 238 9.3E-21 T 29-03-2018 MSG_RS23510 5610ec02fa9ef31c35e3fdccb232107b 247 Pfam PF08348 YheO-like PAS domain 25 129 2.9E-24 T 29-03-2018 IPR013559 YheO-like MSG_RS00700 e7f45bcaae5ecff7bcbf7bb7d1346dee 320 Gene3D G3DSA:3.20.20.70 23 319 4.1E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS00700 e7f45bcaae5ecff7bcbf7bb7d1346dee 320 SUPERFAMILY SSF51569 28 319 1.67E-86 T 29-03-2018 MSG_RS00700 e7f45bcaae5ecff7bcbf7bb7d1346dee 320 Pfam PF00274 Fructose-bisphosphate aldolase class-I 31 205 2.6E-10 T 29-03-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MSG_RS06815 faa598f07281fa7bae38d6e3cdf1e4d7 401 SUPERFAMILY SSF53474 216 235 1.32E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06815 faa598f07281fa7bae38d6e3cdf1e4d7 401 SUPERFAMILY SSF53474 305 395 1.32E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06815 faa598f07281fa7bae38d6e3cdf1e4d7 401 SUPERFAMILY SSF53474 43 170 1.32E-26 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06815 faa598f07281fa7bae38d6e3cdf1e4d7 401 Pfam PF12697 Alpha/beta hydrolase family 59 374 3.3E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06815 faa598f07281fa7bae38d6e3cdf1e4d7 401 Gene3D G3DSA:3.40.50.1820 25 398 4.9E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS05695 97334a4747f7ea81e1bbd9d7150e7ac6 85 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 19 65 5.5E-10 T 29-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit MSG_RS06560 358ec56940de59af803b29b3fc88ad6e 191 Gene3D G3DSA:3.10.180.10 6 118 6.4E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS06560 358ec56940de59af803b29b3fc88ad6e 191 SUPERFAMILY SSF81301 15 148 9.48E-26 T 29-03-2018 MSG_RS06560 358ec56940de59af803b29b3fc88ad6e 191 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 19 144 1.2E-4 T 29-03-2018 IPR018700 Protein of unknown function DUF2204 MSG_RS02935 c43da8a04a3fa21263491e9df6caec66 162 SUPERFAMILY SSF55729 7 141 2.87E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS02935 c43da8a04a3fa21263491e9df6caec66 162 Gene3D G3DSA:3.40.630.30 3 145 6.2E-21 T 29-03-2018 MSG_RS02935 c43da8a04a3fa21263491e9df6caec66 162 Pfam PF00583 Acetyltransferase (GNAT) family 43 139 2.0E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS01985 87e8b94470148b30078e199eeb00f694 392 SUPERFAMILY SSF89796 7 143 1.16E-5 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS01985 87e8b94470148b30078e199eeb00f694 392 Gene3D G3DSA:3.40.50.10540 160 386 7.1E-45 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS01985 87e8b94470148b30078e199eeb00f694 392 Pfam PF02515 CoA-transferase family III 165 346 5.0E-29 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS01985 87e8b94470148b30078e199eeb00f694 392 SUPERFAMILY SSF89796 163 352 2.49E-33 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 Pfam PF11967 Recombination protein O N terminal 1 79 2.0E-27 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 Pfam PF02565 Recombination protein O C terminal 85 237 9.9E-30 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 SUPERFAMILY SSF50249 1 79 6.85E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 Gene3D G3DSA:2.40.50.140 1 81 2.0E-29 T 29-03-2018 MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 25.018 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 184 5.0E-29 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MSG_RS16680 9e1c9c7690487f513e0f68f5cd1e2e4f 265 SUPERFAMILY SSF57863 82 232 1.39E-35 T 29-03-2018 MSG_RS19605 cf9955e0bff2deabcbe57ecde041d12f 127 Gene3D G3DSA:3.10.450.50 3 126 2.1E-23 T 29-03-2018 MSG_RS19605 cf9955e0bff2deabcbe57ecde041d12f 127 SUPERFAMILY SSF54427 11 124 2.75E-26 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS19605 cf9955e0bff2deabcbe57ecde041d12f 127 Pfam PF12680 SnoaL-like domain 15 113 8.8E-16 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS10100 8792390c8db1f001a8898ef84bff9123 273 Gene3D G3DSA:1.10.3720.10 11 266 3.5E-41 T 29-03-2018 MSG_RS10100 8792390c8db1f001a8898ef84bff9123 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 8.0E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS10100 8792390c8db1f001a8898ef84bff9123 273 SUPERFAMILY SSF161098 11 255 1.57E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS08805 282d7f94e6710aa3222843690e782625 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 17 558 1.4E-129 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MSG_RS08805 282d7f94e6710aa3222843690e782625 561 Hamap MF_01491 Ribonuclease J [rnj]. 11 561 39.075 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MSG_RS08805 282d7f94e6710aa3222843690e782625 561 SUPERFAMILY SSF56281 16 434 1.44E-89 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS08805 282d7f94e6710aa3222843690e782625 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 414 5.0E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MSG_RS08805 282d7f94e6710aa3222843690e782625 561 SMART SM00849 28 225 2.5E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS08805 282d7f94e6710aa3222843690e782625 561 PIRSF PIRSF004803 11 561 5.6E-180 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MSG_RS08805 282d7f94e6710aa3222843690e782625 561 Pfam PF12706 Beta-lactamase superfamily domain 56 172 1.7E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS08805 282d7f94e6710aa3222843690e782625 561 Gene3D G3DSA:3.60.15.10 9 458 2.9E-56 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13695 82ac5f62f776a63e0d38446a6e5beff1 191 Gene3D G3DSA:3.10.50.40 77 191 4.9E-19 T 29-03-2018 MSG_RS13695 82ac5f62f776a63e0d38446a6e5beff1 191 SUPERFAMILY SSF54534 86 187 1.77E-19 T 29-03-2018 MSG_RS13695 82ac5f62f776a63e0d38446a6e5beff1 191 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 102 187 1.3E-10 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MSG_RS20970 8eea01aeaf8c0acbef60874bd6d321f4 151 Gene3D G3DSA:3.30.530.20 4 145 1.7E-18 T 29-03-2018 IPR023393 START-like domain MSG_RS20970 8eea01aeaf8c0acbef60874bd6d321f4 151 SUPERFAMILY SSF55961 4 146 6.35E-23 T 29-03-2018 MSG_RS20970 8eea01aeaf8c0acbef60874bd6d321f4 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 141 5.7E-12 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS00905 36ae6da8ccf64e71f374c2863ca0bd10 156 SUPERFAMILY SSF55961 12 155 9.24E-22 T 29-03-2018 MSG_RS00905 36ae6da8ccf64e71f374c2863ca0bd10 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 12 154 8.0E-12 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS00905 36ae6da8ccf64e71f374c2863ca0bd10 156 Gene3D G3DSA:3.30.530.20 3 156 2.3E-23 T 29-03-2018 IPR023393 START-like domain MSG_RS20340 50dc7de55263f5cb1ee51ca700839732 507 Gene3D G3DSA:3.40.47.10 6 263 2.2E-9 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20340 50dc7de55263f5cb1ee51ca700839732 507 SUPERFAMILY SSF53901 28 145 1.4E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20340 50dc7de55263f5cb1ee51ca700839732 507 SUPERFAMILY SSF53901 249 265 1.4E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20340 50dc7de55263f5cb1ee51ca700839732 507 Gene3D G3DSA:3.40.47.10 264 399 1.7E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS20340 50dc7de55263f5cb1ee51ca700839732 507 SUPERFAMILY SSF53901 290 405 5.21E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MSG_RS08665 9abf4bda8d3e279377ab221649558a05 190 Gene3D G3DSA:1.10.357.10 1 189 8.4E-18 T 29-03-2018 MSG_RS08665 9abf4bda8d3e279377ab221649558a05 190 SUPERFAMILY SSF46689 2 59 9.75E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS18420 0236c80f302630157af6105770ac7aaf 178 Gene3D G3DSA:3.90.79.10 5 176 7.2E-31 T 29-03-2018 MSG_RS18420 0236c80f302630157af6105770ac7aaf 178 Pfam PF00293 NUDIX domain 44 154 1.2E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MSG_RS18420 0236c80f302630157af6105770ac7aaf 178 SUPERFAMILY SSF55811 5 175 1.9E-37 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MSG_RS09900 045e98040bb037f0a105dab9860727ac 139 Pfam PF01478 Type IV leader peptidase family 9 110 1.9E-13 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MSG_RS07430 37e34c06fa8e80a14992aacbe1d8a1b3 125 SUPERFAMILY SSF109755 26 121 1.44E-8 T 29-03-2018 MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 Gene3D G3DSA:1.20.1250.20 5 189 4.0E-34 T 29-03-2018 MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 Gene3D G3DSA:1.20.1250.20 197 398 4.0E-20 T 29-03-2018 MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 SUPERFAMILY SSF103473 7 396 4.32E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 Pfam PF07690 Major Facilitator Superfamily 17 247 1.1E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS13300 b800442de5ce4cbd186e6b66f7b48d62 415 Pfam PF07690 Major Facilitator Superfamily 249 393 8.4E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS01700 c93cca262cc92431652eabb1c3f5374b 146 SUPERFAMILY SSF55961 1 144 4.58E-25 T 29-03-2018 MSG_RS01700 c93cca262cc92431652eabb1c3f5374b 146 Gene3D G3DSA:3.30.530.20 1 146 5.9E-22 T 29-03-2018 IPR023393 START-like domain MSG_RS01700 c93cca262cc92431652eabb1c3f5374b 146 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 137 4.3E-12 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 MSG_RS13345 d3fd19214c84f76f4ef0a19def2e9e3a 232 Gene3D G3DSA:3.30.70.100 2 106 1.7E-5 T 29-03-2018 MSG_RS13465 39a9852ac44dcbfa5c674ca414bcbb18 314 SUPERFAMILY SSF51412 4 302 1.05E-57 T 29-03-2018 MSG_RS13465 39a9852ac44dcbfa5c674ca414bcbb18 314 Gene3D G3DSA:3.20.20.70 4 311 6.3E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS13465 39a9852ac44dcbfa5c674ca414bcbb18 314 Pfam PF03060 Nitronate monooxygenase 81 294 4.5E-40 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS13465 39a9852ac44dcbfa5c674ca414bcbb18 314 Pfam PF03060 Nitronate monooxygenase 8 72 1.5E-15 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS03700 6067a657bf47fc594b78ef07ab54e337 325 Pfam PF01578 Cytochrome C assembly protein 108 319 6.9E-46 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MSG_RS03700 6067a657bf47fc594b78ef07ab54e337 325 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 85 322 6.9E-77 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 MSG_RS22145 fca09af9467cc90e3b547d795c84e28f 88 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 13 70 6.8E-19 T 29-03-2018 MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 44 259 1.1E-35 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 1.1E-9 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.1E-9 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 1.1E-9 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 SUPERFAMILY SSF56601 1 282 7.57E-57 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS08175 780ea444d19617bb60156cd5ec00a4c3 293 Gene3D G3DSA:3.40.710.10 9 291 3.1E-49 T 29-03-2018 MSG_RS09460 585d60c12fcf7cae5eaadb08114bf9e2 271 SUPERFAMILY SSF56281 15 255 6.17E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS09460 585d60c12fcf7cae5eaadb08114bf9e2 271 Gene3D G3DSA:3.60.15.10 1 271 8.7E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS09460 585d60c12fcf7cae5eaadb08114bf9e2 271 Pfam PF12706 Beta-lactamase superfamily domain 29 227 9.1E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS14415 765b055e3922afc8aade82572ca93174 511 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 49 488 5.3E-87 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 MSG_RS17305 305bbc6cdc7bb9f3526c062233e9ea1f 221 PIRSF PIRSF012637 2 221 3.9E-86 T 29-03-2018 IPR016601 Uncharacterised conserved protein UCP012637 MSG_RS04335 dfbe23b42247713ef58a1f167788fce8 29 TIGRFAM TIGR03969 mycofactocin: mycofactocin precursor 8 29 2.4E-15 T 29-03-2018 IPR023988 Mycofactocin MSG_RS17995 17517ba8f1a191cea6db6e7d6ed1f925 396 SUPERFAMILY SSF89796 1 394 8.24E-80 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17995 17517ba8f1a191cea6db6e7d6ed1f925 396 Gene3D G3DSA:3.40.50.10540 1 396 3.1E-84 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS17995 17517ba8f1a191cea6db6e7d6ed1f925 396 Pfam PF02515 CoA-transferase family III 5 370 8.7E-60 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS07360 54a806f1cdf8ea607ed1102f5bf77765 333 SUPERFAMILY SSF51735 2 324 4.93E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS07360 54a806f1cdf8ea607ed1102f5bf77765 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 235 4.2E-20 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS07360 54a806f1cdf8ea607ed1102f5bf77765 333 Gene3D G3DSA:3.40.50.720 1 331 5.6E-44 T 29-03-2018 MSG_RS17455 c9724efb39f189cf34c9d4e6642a578b 164 Gene3D G3DSA:3.10.129.10 1 159 2.9E-37 T 29-03-2018 MSG_RS17455 c9724efb39f189cf34c9d4e6642a578b 164 SUPERFAMILY SSF54637 8 159 4.06E-45 T 29-03-2018 IPR029069 HotDog domain MSG_RS17455 c9724efb39f189cf34c9d4e6642a578b 164 Pfam PF01575 MaoC like domain 18 137 3.9E-27 T 29-03-2018 IPR002539 MaoC-like domain MSG_RS02255 a925829a67e64747f21cc384ce0fe76f 479 Pfam PF07690 Major Facilitator Superfamily 40 405 9.6E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS02255 a925829a67e64747f21cc384ce0fe76f 479 SUPERFAMILY SSF103473 1 446 3.92E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS02255 a925829a67e64747f21cc384ce0fe76f 479 Gene3D G3DSA:1.20.1250.20 25 221 3.0E-12 T 29-03-2018 MSG_RS02255 a925829a67e64747f21cc384ce0fe76f 479 Gene3D G3DSA:1.20.1250.20 222 450 1.9E-19 T 29-03-2018 MSG_RS17645 9433fdd669d848db21e237478e0518d9 239 SUPERFAMILY SSF51445 56 198 2.0E-6 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MSG_RS17645 9433fdd669d848db21e237478e0518d9 239 Pfam PF08924 Domain of unknown function (DUF1906) 50 175 2.7E-28 T 29-03-2018 IPR015020 Protein of unknown function DUF1906 MSG_RS17645 9433fdd669d848db21e237478e0518d9 239 Gene3D G3DSA:3.20.20.80 41 228 7.5E-19 T 29-03-2018 MSG_RS17845 058f5e231429ed1804e81583de3aca68 340 SUPERFAMILY SSF51679 17 323 8.24E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS17845 058f5e231429ed1804e81583de3aca68 340 Pfam PF00296 Luciferase-like monooxygenase 16 317 3.4E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS17845 058f5e231429ed1804e81583de3aca68 340 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 25 339 1.9E-154 T 29-03-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted MSG_RS17845 058f5e231429ed1804e81583de3aca68 340 Gene3D G3DSA:3.20.20.30 12 338 1.1E-52 T 29-03-2018 MSG_RS21790 95575e4eadbf1ddfe733feb5b0805032 166 Gene3D G3DSA:3.30.429.10 2 144 8.3E-22 T 29-03-2018 MSG_RS17585 ecb17968da7cae42d5f1f9649bc96fbd 375 Pfam PF01594 AI-2E family transporter 59 363 8.6E-48 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like MSG_RS20285 899ca1e2f3fb029dfe6279a99cb92cde 108 SUPERFAMILY SSF140453 4 96 1.2E-9 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS20285 899ca1e2f3fb029dfe6279a99cb92cde 108 Gene3D G3DSA:1.10.287.1060 1 98 7.6E-10 T 29-03-2018 MSG_RS11965 0ab19b0fa5526ff273cec770a302a0d6 121 SUPERFAMILY SSF57850 10 86 2.35E-24 T 29-03-2018 MSG_RS11965 0ab19b0fa5526ff273cec770a302a0d6 121 Gene3D G3DSA:3.30.40.10 2 83 6.0E-17 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type MSG_RS11965 0ab19b0fa5526ff273cec770a302a0d6 121 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 16 83 5.6E-11 T 29-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 MSG_RS05455 1b129963586b3d02b6f14712e70852a9 145 SUPERFAMILY SSF52777 24 137 9.0E-12 T 29-03-2018 MSG_RS05455 1b129963586b3d02b6f14712e70852a9 145 Gene3D G3DSA:3.30.559.10 7 144 4.1E-12 T 29-03-2018 MSG_RS17405 fc410058d03b59d379a7344637222d39 142 Pfam PF04075 F420H(2)-dependent quinone reductase 42 116 7.0E-14 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS17405 fc410058d03b59d379a7344637222d39 142 Gene3D G3DSA:2.30.110.10 6 137 8.7E-14 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS17405 fc410058d03b59d379a7344637222d39 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 42 118 2.6E-14 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS02340 a1ebf39726dcb6c3d7e36df68baa0bb4 302 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 39 269 2.9E-49 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 28 42 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 7.0E-55 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Gene3D G3DSA:3.40.50.800 361 462 1.6E-25 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Pfam PF03129 Anticodon binding domain 369 456 4.1E-21 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 160 286 2.9E-8 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Gene3D G3DSA:3.30.930.10 7 226 2.3E-51 T 29-03-2018 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Gene3D G3DSA:3.30.930.10 227 360 1.1E-38 T 29-03-2018 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 SUPERFAMILY SSF55681 9 372 3.94E-120 T 29-03-2018 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 10 233 1.9E-78 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 6 461 48.98 T 29-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 MSG_RS16655 18ead9c1a8de574b21485b12ae1a200f 463 SUPERFAMILY SSF52954 356 461 1.19E-32 T 29-03-2018 IPR004154 Anticodon-binding MSG_RS05920 1b9e6da062a9404b2bcf367a74f1a989 212 Gene3D G3DSA:3.40.50.2020 54 212 1.2E-20 T 29-03-2018 MSG_RS05920 1b9e6da062a9404b2bcf367a74f1a989 212 SUPERFAMILY SSF53271 42 211 9.97E-15 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MSG_RS05195 d0e181b3fbca9f30f29d7baf81175b13 142 SUPERFAMILY SSF54593 4 137 3.85E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS05195 d0e181b3fbca9f30f29d7baf81175b13 142 Gene3D G3DSA:3.10.180.10 1 140 3.1E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS05195 d0e181b3fbca9f30f29d7baf81175b13 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 130 2.1E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS06355 c6770779edb020d64b7818b6dc34bd1f 175 Gene3D G3DSA:2.60.120.10 12 150 1.4E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS06355 c6770779edb020d64b7818b6dc34bd1f 175 SUPERFAMILY SSF51182 8 133 1.57E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS06355 c6770779edb020d64b7818b6dc34bd1f 175 Pfam PF07883 Cupin domain 46 109 2.3E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MSG_RS04645 641c0e8c952044e7b679766762c5c231 271 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 31 212 6.0E-32 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MSG_RS04645 641c0e8c952044e7b679766762c5c231 271 Gene3D G3DSA:3.30.420.40 14 270 2.2E-52 T 29-03-2018 MSG_RS04645 641c0e8c952044e7b679766762c5c231 271 SUPERFAMILY SSF53067 23 260 7.34E-50 T 29-03-2018 MSG_RS04645 641c0e8c952044e7b679766762c5c231 271 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 124 144 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MSG_RS24070 1d6afc6430f17816ee08cfca9cfb3b11 376 Pfam PF01145 SPFH domain / Band 7 family 24 186 6.6E-12 T 29-03-2018 IPR001107 Band 7 domain MSG_RS24070 1d6afc6430f17816ee08cfca9cfb3b11 376 SUPERFAMILY SSF117892 37 176 1.96E-24 T 29-03-2018 IPR001107 Band 7 domain MSG_RS23710 2f4583a3f40ef54911a6b33ffdb62a23 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 1.1E-21 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS23710 2f4583a3f40ef54911a6b33ffdb62a23 157 SMART SM00226 5 130 2.1E-47 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS23710 2f4583a3f40ef54911a6b33ffdb62a23 157 Gene3D G3DSA:3.40.50.2300 3 135 6.8E-37 T 29-03-2018 MSG_RS23710 2f4583a3f40ef54911a6b33ffdb62a23 157 SUPERFAMILY SSF52788 5 128 3.92E-35 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 SUPERFAMILY SSF56425 290 466 9.77E-27 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 Pfam PF00890 FAD binding domain 8 514 1.1E-75 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 SUPERFAMILY SSF51905 2 117 4.64E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 SUPERFAMILY SSF51905 191 305 4.64E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 SUPERFAMILY SSF51905 472 530 4.64E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS21480 fcba758cae59b1dd4ce3caf838d5887d 537 Gene3D G3DSA:3.50.50.60 2 530 3.9E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS19640 395c9346da067eda67e7359a4885f0de 224 Pfam PF06271 RDD family 72 216 2.8E-25 T 29-03-2018 IPR010432 RDD MSG_RS24360 38b36b4bf4ed626d7a40bd88476c75be 170 Gene3D G3DSA:2.60.40.1220 30 125 1.7E-24 T 29-03-2018 MSG_RS24360 38b36b4bf4ed626d7a40bd88476c75be 170 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 140 169 0.0018 T 29-03-2018 MSG_RS24360 38b36b4bf4ed626d7a40bd88476c75be 170 Pfam PF04234 CopC domain 31 123 1.8E-20 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MSG_RS24360 38b36b4bf4ed626d7a40bd88476c75be 170 SUPERFAMILY SSF81296 30 123 3.57E-22 T 29-03-2018 IPR014756 Immunoglobulin E-set MSG_RS17090 191d427e8b855b07bfafa67533ccc124 141 SUPERFAMILY SSF52499 2 137 1.22E-16 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS17090 191d427e8b855b07bfafa67533ccc124 141 Gene3D G3DSA:3.40.50.850 1 115 2.8E-11 T 29-03-2018 MSG_RS17090 191d427e8b855b07bfafa67533ccc124 141 Pfam PF00857 Isochorismatase family 4 108 1.0E-6 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS04060 6ea445832ddb9217d4db6d4a65ce2d66 66 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 51 3.3E-18 T 29-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 SUPERFAMILY SSF53474 7 187 2.57E-76 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 SUPERFAMILY SSF53474 214 319 2.57E-76 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 Pfam PF00561 alpha/beta hydrolase fold 29 305 1.9E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 35 53 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 101 114 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 294 316 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 260 276 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 55 70 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 PRINTS PR00412 Epoxide hydrolase signature 115 128 2.5E-33 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS22875 19da614bec6e48644c3b0f02c1cf63da 323 Gene3D G3DSA:3.40.50.1820 7 322 8.8E-72 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13355 b499c496029a9968f9543dd67873b6ff 130 Gene3D G3DSA:3.30.429.10 1 130 9.9E-30 T 29-03-2018 MSG_RS13355 b499c496029a9968f9543dd67873b6ff 130 SUPERFAMILY SSF55331 2 128 1.83E-37 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily MSG_RS13355 b499c496029a9968f9543dd67873b6ff 130 Pfam PF14552 Tautomerase enzyme 38 118 8.4E-27 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 MSG_RS02990 408e6b2bc08c86f5d351182ee9120a63 283 Gene3D G3DSA:3.40.960.10 179 281 3.0E-13 T 29-03-2018 MSG_RS02990 408e6b2bc08c86f5d351182ee9120a63 283 SUPERFAMILY SSF52980 177 263 1.82E-6 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MSG_RS02990 408e6b2bc08c86f5d351182ee9120a63 283 Pfam PF04480 Protein of unknown function (DUF559) 220 262 8.1E-5 T 29-03-2018 IPR007569 Domain of unknown function DUF559 MSG_RS22835 143d9e101412ec2f722c434abc9b4b9b 474 PRINTS PR01217 Proline rich extensin signature 383 400 3.1E-9 T 29-03-2018 MSG_RS22835 143d9e101412ec2f722c434abc9b4b9b 474 PRINTS PR01217 Proline rich extensin signature 402 427 3.1E-9 T 29-03-2018 MSG_RS22835 143d9e101412ec2f722c434abc9b4b9b 474 PRINTS PR01217 Proline rich extensin signature 260 276 3.1E-9 T 29-03-2018 MSG_RS22835 143d9e101412ec2f722c434abc9b4b9b 474 PRINTS PR01217 Proline rich extensin signature 342 363 3.1E-9 T 29-03-2018 MSG_RS24080 0f022e22cb0e467a125a25850d00294d 142 Pfam PF04138 GtrA-like protein 23 139 2.7E-20 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 MSG_RS09640 5705141b28b224eeecc5af56cdb5c308 151 Pfam PF03994 Domain of Unknown Function (DUF350) 96 150 4.5E-8 T 29-03-2018 IPR007140 Protein of unknown function DUF350 MSG_RS09640 5705141b28b224eeecc5af56cdb5c308 151 Pfam PF03994 Domain of Unknown Function (DUF350) 25 79 1.1E-13 T 29-03-2018 IPR007140 Protein of unknown function DUF350 MSG_RS18180 fe9634b8c64030444e51ac52f56442e8 116 Gene3D G3DSA:2.30.110.10 4 115 7.5E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS04775 1e010a66c0b7f5061dd8799723677900 358 Pfam PF01757 Acyltransferase family 12 326 3.2E-16 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS23530 f2dfd3316f5015df067fe2d813347091 161 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 40 160 9.2E-27 T 29-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 MSG_RS04530 326b99ae57f8fa293fdd480cbc54b3d9 299 Pfam PF03781 Sulfatase-modifying factor enzyme 1 3 293 1.3E-85 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MSG_RS04530 326b99ae57f8fa293fdd480cbc54b3d9 299 Gene3D G3DSA:3.90.1580.10 1 299 4.6E-86 T 29-03-2018 MSG_RS04530 326b99ae57f8fa293fdd480cbc54b3d9 299 SUPERFAMILY SSF56436 3 295 1.55E-88 T 29-03-2018 IPR016187 C-type lectin fold MSG_RS09085 30abfffc97107c4b7785e9a7578d806f 225 PIRSF PIRSF010219 2 215 2.6E-84 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 MSG_RS09085 30abfffc97107c4b7785e9a7578d806f 225 Pfam PF11361 Protein of unknown function (DUF3159) 18 202 3.0E-66 T 29-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 Gene3D G3DSA:3.40.50.200 71 416 5.7E-62 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 122 135 5.9E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 5.9E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 PRINTS PR00723 Subtilisin serine protease family (S8) signature 86 105 5.9E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 Pfam PF00082 Subtilase family 86 392 3.1E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 SUPERFAMILY SSF52743 69 242 2.88E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 SUPERFAMILY SSF52743 273 401 2.88E-57 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 126 136 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site MSG_RS02405 77d6646bad6758b295b77a530c1fc63d 463 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 75 458 5.9E-119 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin MSG_RS16570 d19e1dc2ce930fa2ee869bf6c1789cd3 307 SUPERFAMILY SSF56563 36 296 1.16E-7 T 29-03-2018 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SUPERFAMILY SSF52540 337 554 6.71E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Gene3D G3DSA:2.60.200.20 2 100 1.4E-15 T 29-03-2018 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SUPERFAMILY SSF49879 15 109 9.18E-19 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Pfam PF00498 FHA domain 251 314 9.5E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Pfam PF00498 FHA domain 19 82 5.5E-12 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Gene3D G3DSA:3.40.50.300 338 607 2.5E-61 T 29-03-2018 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SMART SM00382 365 549 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Pfam PF00005 ABC transporter 356 503 2.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SMART SM00240 250 300 6.4E-15 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SMART SM00240 18 68 4.2E-11 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Pfam PF01061 ABC-2 type transporter 617 832 1.1E-18 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 Gene3D G3DSA:2.60.200.20 130 335 2.6E-19 T 29-03-2018 MSG_RS12265 d7e8da3ad558f93369346d4008645b7b 887 SUPERFAMILY SSF49879 200 321 3.83E-24 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MSG_RS11355 09943f90877266a77968402281083d72 188 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 3 160 3.3E-49 T 29-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain MSG_RS11355 09943f90877266a77968402281083d72 188 Pfam PF13298 DNA polymerase Ligase (LigD) 38 142 1.7E-32 T 29-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 SUPERFAMILY SSF69593 61 211 4.58E-13 T 29-03-2018 MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 SUPERFAMILY SSF69593 251 301 4.58E-13 T 29-03-2018 MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 SMART SM00563 88 208 3.9E-4 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 Pfam PF01553 Acyltransferase 76 204 6.9E-8 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 Gene3D G3DSA:3.40.1130.10 51 307 3.0E-12 T 29-03-2018 MSG_RS08340 7053b129b2d11f4c89c5d4f6b108265c 311 PIRSF PIRSF016753 15 311 3.1E-96 T 29-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted MSG_RS13935 cf3c59760d7862d2d309d7a22e966f01 432 Pfam PF00067 Cytochrome P450 43 134 2.2E-5 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13935 cf3c59760d7862d2d309d7a22e966f01 432 Pfam PF00067 Cytochrome P450 247 397 1.2E-17 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13935 cf3c59760d7862d2d309d7a22e966f01 432 SUPERFAMILY SSF48264 44 407 7.2E-44 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MSG_RS13935 cf3c59760d7862d2d309d7a22e966f01 432 Gene3D G3DSA:1.10.630.10 26 168 9.1E-11 T 29-03-2018 MSG_RS13935 cf3c59760d7862d2d309d7a22e966f01 432 Gene3D G3DSA:1.10.630.10 169 432 4.0E-32 T 29-03-2018 MSG_RS13000 6e9612ce95445d21357da2ffc794f9db 248 Gene3D G3DSA:1.10.3720.10 2 245 2.6E-35 T 29-03-2018 MSG_RS13000 6e9612ce95445d21357da2ffc794f9db 248 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 14 234 2.1E-86 T 29-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 MSG_RS13000 6e9612ce95445d21357da2ffc794f9db 248 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 36 237 7.9E-67 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MSG_RS13000 6e9612ce95445d21357da2ffc794f9db 248 SUPERFAMILY SSF161098 4 235 4.06E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS13000 6e9612ce95445d21357da2ffc794f9db 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 235 6.4E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS16390 80d57392bfc47bcff9f73dc71d928ee2 288 Gene3D G3DSA:1.20.1290.10 25 121 0.37 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16390 80d57392bfc47bcff9f73dc71d928ee2 288 Gene3D G3DSA:1.20.1290.10 123 276 2.9E-16 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16390 80d57392bfc47bcff9f73dc71d928ee2 288 SUPERFAMILY SSF69118 142 264 5.9E-21 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS23240 0c29ac967eeb82129d9fe14b64bf59be 208 SMART SM00331 9 203 5.3E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23240 0c29ac967eeb82129d9fe14b64bf59be 208 Gene3D G3DSA:3.60.40.10 4 208 3.9E-17 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23240 0c29ac967eeb82129d9fe14b64bf59be 208 SUPERFAMILY SSF81606 26 183 2.35E-10 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS23240 0c29ac967eeb82129d9fe14b64bf59be 208 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 36 192 2.7E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MSG_RS18775 4b4e33311609139e898c05572a4487f5 180 Pfam PF06210 Protein of unknown function (DUF1003) 39 139 2.0E-38 T 29-03-2018 IPR010406 Protein of unknown function DUF1003 MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 SUPERFAMILY SSF55729 83 138 3.61E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 TIGRFAM TIGR01248 drrC: daunorubicin resistance protein C 91 242 5.0E-53 T 29-03-2018 IPR005943 Daunorubicin resistance protein C MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 47 274 3.9E-51 T 29-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 Pfam PF01061 ABC-2 type transporter 29 237 1.1E-16 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 Gene3D G3DSA:3.40.630.30 83 221 4.2E-5 T 29-03-2018 MSG_RS08025 7f34b574f0cfb6570e6136b3722d2e52 277 PIRSF PIRSF006648 4 275 2.9E-60 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS06405 0bd4354312df44f099d04d36f223f828 155 Gene3D G3DSA:2.60.120.10 1 155 1.7E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS06405 0bd4354312df44f099d04d36f223f828 155 Pfam PF12973 ChrR Cupin-like domain 43 108 2.7E-6 T 29-03-2018 IPR025979 ChrR-like cupin domain MSG_RS06405 0bd4354312df44f099d04d36f223f828 155 SUPERFAMILY SSF51182 6 136 1.5E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS14955 99f32affe3a4fdc4d2d6bc9fccc2b7ff 140 Pfam PF12695 Alpha/beta hydrolase family 11 121 9.0E-9 T 29-03-2018 IPR029059 Alpha/beta hydrolase fold-5 MSG_RS14955 99f32affe3a4fdc4d2d6bc9fccc2b7ff 140 Gene3D G3DSA:3.40.50.1820 1 140 1.1E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14955 99f32affe3a4fdc4d2d6bc9fccc2b7ff 140 SUPERFAMILY SSF53474 8 138 7.43E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11885 2757f5bfc9c60fa41dc4dc415850690e 103 SUPERFAMILY SSF54909 2 101 2.49E-8 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS11885 2757f5bfc9c60fa41dc4dc415850690e 103 Gene3D G3DSA:3.30.70.100 1 103 1.1E-10 T 29-03-2018 MSG_RS11885 2757f5bfc9c60fa41dc4dc415850690e 103 Pfam PF07978 NIPSNAP 3 100 8.7E-9 T 29-03-2018 IPR012577 NIPSNAP MSG_RS17560 8ae487a4610a3d8790dc9dbf42710c79 75 Pfam PF12277 Protein of unknown function (DUF3618) 3 48 9.0E-16 T 29-03-2018 IPR022062 Protein of unknown function DUF3618 MSG_RS03390 d01a1d67760f0bbdd23daeff7f29230c 450 SUPERFAMILY SSF48371 171 375 3.41E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 MSG_RS03390 d01a1d67760f0bbdd23daeff7f29230c 450 Gene3D G3DSA:1.25.10.10 155 406 1.7E-5 T 29-03-2018 IPR011989 Armadillo-like helical MSG_RS03390 d01a1d67760f0bbdd23daeff7f29230c 450 Pfam PF04286 Protein of unknown function (DUF445) 86 448 1.1E-104 T 29-03-2018 IPR007383 Protein of unknown function DUF445 MSG_RS03705 0fc1a403885757fdfa868febf53f71a4 411 Gene3D G3DSA:3.40.50.300 158 405 2.1E-28 T 29-03-2018 MSG_RS03705 0fc1a403885757fdfa868febf53f71a4 411 SUPERFAMILY SSF52540 160 395 1.62E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS03705 0fc1a403885757fdfa868febf53f71a4 411 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 161 371 1.0E-10 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MSG_RS02580 bc96747984a3ec0d3204593afb75f2aa 185 Gene3D G3DSA:1.20.1290.10 16 185 1.3E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS02580 bc96747984a3ec0d3204593afb75f2aa 185 SUPERFAMILY SSF69118 15 180 8.93E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS02580 bc96747984a3ec0d3204593afb75f2aa 185 Pfam PF02627 Carboxymuconolactone decarboxylase family 53 109 4.1E-7 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS20600 75c40549dc0eb1cafb72c0083c5ad83f 159 Gene3D G3DSA:3.10.180.10 17 137 9.2E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS20600 75c40549dc0eb1cafb72c0083c5ad83f 159 SUPERFAMILY SSF54593 23 136 3.86E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS13100 f6b146b73492ed8694c55ab1fd84314b 412 PIRSF PIRSF000138 15 406 5.1E-125 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 MSG_RS13100 f6b146b73492ed8694c55ab1fd84314b 412 SUPERFAMILY SSF51395 35 401 1.94E-96 T 29-03-2018 MSG_RS13100 f6b146b73492ed8694c55ab1fd84314b 412 Pfam PF01070 FMN-dependent dehydrogenase 44 402 1.2E-124 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MSG_RS13100 f6b146b73492ed8694c55ab1fd84314b 412 Gene3D G3DSA:3.20.20.70 33 406 1.9E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS13100 f6b146b73492ed8694c55ab1fd84314b 412 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 299 305 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 MSG_RS04950 ff6eb5bc172ac7208fcf07155473675a 255 Pfam PF14494 Domain of unknown function (DUF4436) 3 246 2.1E-85 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS05840 d9c5e884d841fae13bf435248ab94f2e 140 Pfam PF06262 Zincin-like metallopeptidase 86 130 4.2E-5 T 29-03-2018 IPR010428 Zincin-like metallopeptidase MSG_RS05840 d9c5e884d841fae13bf435248ab94f2e 140 SUPERFAMILY SSF55486 13 135 6.59E-19 T 29-03-2018 MSG_RS01800 3ae0600ebf689c96cec38d3fd0b87398 379 SUPERFAMILY SSF51735 2 102 3.51E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS01800 3ae0600ebf689c96cec38d3fd0b87398 379 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 72 1.5E-9 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS01800 3ae0600ebf689c96cec38d3fd0b87398 379 Gene3D G3DSA:3.40.50.720 1 132 4.3E-19 T 29-03-2018 MSG_RS04420 3cfcbec3f6266e9ddfa8a5ec8f59d3f2 257 Pfam PF01925 Sulfite exporter TauE/SafE 11 248 2.7E-32 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MSG_RS19600 b76d9a71a7836581856f38ed3a0231c1 245 Pfam PF03006 Haemolysin-III related 35 237 1.2E-40 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MSG_RS19600 b76d9a71a7836581856f38ed3a0231c1 245 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 37 244 3.6E-64 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 MSG_RS08105 8e72e8aa29eafe1d7fb58bdabe38d5cb 97 Gene3D G3DSA:3.30.70.100 3 97 5.9E-25 T 29-03-2018 MSG_RS08105 8e72e8aa29eafe1d7fb58bdabe38d5cb 97 SUPERFAMILY SSF54975 5 95 2.62E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS08105 8e72e8aa29eafe1d7fb58bdabe38d5cb 97 ProSitePatterns PS00151 Acylphosphatase signature 2. 36 52 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS08105 8e72e8aa29eafe1d7fb58bdabe38d5cb 97 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS08105 8e72e8aa29eafe1d7fb58bdabe38d5cb 97 Pfam PF00708 Acylphosphatase 9 94 7.5E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MSG_RS04375 8859c01fabc21e9784073d17777205ce 267 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 264 2.3E-49 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS18810 dec55d717fcaf9b88ab83f0e1fc9ed95 222 Gene3D G3DSA:3.40.50.150 13 222 3.8E-32 T 29-03-2018 MSG_RS18810 dec55d717fcaf9b88ab83f0e1fc9ed95 222 SUPERFAMILY SSF53335 45 221 5.03E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS18810 dec55d717fcaf9b88ab83f0e1fc9ed95 222 Pfam PF01596 O-methyltransferase 42 219 4.8E-27 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MSG_RS22455 23fbfbe4eba289e9011b4098008784a3 261 Gene3D G3DSA:3.90.850.10 1 261 2.7E-51 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS22455 23fbfbe4eba289e9011b4098008784a3 261 SUPERFAMILY SSF56529 2 260 7.17E-76 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS22455 23fbfbe4eba289e9011b4098008784a3 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 103 258 4.6E-10 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MSG_RS14610 14db6d61056bc7fab929dd1d4931a8ed 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 1.3E-68 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MSG_RS14610 14db6d61056bc7fab929dd1d4931a8ed 208 Gene3D G3DSA:3.40.50.10230 2 208 1.2E-74 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MSG_RS14610 14db6d61056bc7fab929dd1d4931a8ed 208 SUPERFAMILY SSF63965 2 205 4.71E-69 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MSG_RS07755 d82094f0476c133c5c1e27a9afc5433d 112 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 1 112 3.0E-36 T 29-03-2018 IPR020535 Low molecular weight antigen Cfp6 MSG_RS07755 d82094f0476c133c5c1e27a9afc5433d 112 Pfam PF10756 Bacterial PH domain 39 109 2.8E-21 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 MSG_RS02220 b9997da60e35efb4581b7ebde2314cdd 176 Gene3D G3DSA:3.30.310.70 15 167 3.4E-25 T 29-03-2018 IPR005180 Domain of unknown function DUF302 MSG_RS02220 b9997da60e35efb4581b7ebde2314cdd 176 SUPERFAMILY SSF103247 68 164 1.24E-12 T 29-03-2018 IPR005180 Domain of unknown function DUF302 MSG_RS14480 e1630c2979e78edd1123c32697b5c27b 185 Pfam PF00857 Isochorismatase family 3 183 1.3E-30 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS14480 e1630c2979e78edd1123c32697b5c27b 185 SUPERFAMILY SSF52499 2 183 1.15E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MSG_RS14480 e1630c2979e78edd1123c32697b5c27b 185 Gene3D G3DSA:3.40.50.850 1 185 5.1E-57 T 29-03-2018 MSG_RS14780 f1cfb505c18d38ebddbfb84c61c6cfea 201 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 60 166 1.0E-44 T 29-03-2018 IPR020235 Low molecular weight antigen MTB12 MSG_RS01300 5b8481a1b54fcf511fa93b0ba9f6575a 365 SUPERFAMILY SSF51679 48 364 9.29E-65 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS01300 5b8481a1b54fcf511fa93b0ba9f6575a 365 TIGRFAM TIGR04465 ArgArg_F420: TAT-translocated F420-dependent dehydrogenase, FGD2 family 4 365 2.8E-209 T 29-03-2018 IPR031017 TAT-translocated F420-dependent dehydrogenase, FGD2 family MSG_RS01300 5b8481a1b54fcf511fa93b0ba9f6575a 365 Gene3D G3DSA:3.20.20.30 45 365 5.5E-66 T 29-03-2018 MSG_RS01300 5b8481a1b54fcf511fa93b0ba9f6575a 365 Pfam PF00296 Luciferase-like monooxygenase 58 338 4.5E-57 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS01300 5b8481a1b54fcf511fa93b0ba9f6575a 365 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 49 364 2.5E-74 T 29-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related MSG_RS22425 dd7550b0e7e405e852aa767a31dfe906 381 Pfam PF13469 Sulfotransferase family 90 338 1.5E-59 T 29-03-2018 MSG_RS22425 dd7550b0e7e405e852aa767a31dfe906 381 Gene3D G3DSA:3.40.50.300 54 375 3.7E-33 T 29-03-2018 MSG_RS22425 dd7550b0e7e405e852aa767a31dfe906 381 SUPERFAMILY SSF52540 212 354 7.21E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22425 dd7550b0e7e405e852aa767a31dfe906 381 SUPERFAMILY SSF52540 84 150 7.21E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS21715 8a7e0d4c465e5e695038d65d30e3b9ee 154 PIRSF PIRSF030042 4 62 0.005 T 29-03-2018 IPR016942 Uncharacterised conserved protein UCP030042 MSG_RS21715 8a7e0d4c465e5e695038d65d30e3b9ee 154 PIRSF PIRSF030042 70 153 3.9E-9 T 29-03-2018 IPR016942 Uncharacterised conserved protein UCP030042 MSG_RS21715 8a7e0d4c465e5e695038d65d30e3b9ee 154 Pfam PF14340 Domain of unknown function (DUF4395) 13 148 5.8E-45 T 29-03-2018 IPR025508 Domain of unknown function DUF4395 MSG_RS01000 e644e226655c0f5191435bcfe8bea2dc 190 Pfam PF07336 Putative stress-induced transcription regulator 2 104 1.9E-5 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator MSG_RS01000 e644e226655c0f5191435bcfe8bea2dc 190 Pfam PF11706 CGNR zinc finger 123 166 1.2E-12 T 29-03-2018 IPR021005 Zinc finger, CGNR MSG_RS01000 e644e226655c0f5191435bcfe8bea2dc 190 Gene3D G3DSA:1.10.3300.10 1 168 6.6E-23 T 29-03-2018 IPR023286 ABATE domain MSG_RS01000 e644e226655c0f5191435bcfe8bea2dc 190 SUPERFAMILY SSF160904 1 165 1.23E-24 T 29-03-2018 MSG_RS00960 0509a08755c6b48e6fb9f96ea6cea3f5 434 Pfam PF01699 Sodium/calcium exchanger protein 52 201 1.8E-10 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MSG_RS00960 0509a08755c6b48e6fb9f96ea6cea3f5 434 Pfam PF01699 Sodium/calcium exchanger protein 234 371 2.4E-9 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MSG_RS24575 080d7ebb99bb0f3e44123f22b778964c 466 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 13 332 1.6E-78 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS24575 080d7ebb99bb0f3e44123f22b778964c 466 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 176 265 5.3E-19 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 TIGRFAM TIGR04284 aldehy_Rv0768: aldehyde dehydrogenase, Rv0768 family 10 487 1.3E-282 T 29-03-2018 IPR026460 Aldehyde dehydrogenase, Rv0768 family MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 Pfam PF00171 Aldehyde dehydrogenase family 21 484 2.6E-145 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 Gene3D G3DSA:3.40.605.10 7 274 3.3E-78 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 SUPERFAMILY SSF53720 10 485 6.41E-147 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS22005 51d19c7d973bbdd619c3a5c4611891db 488 Gene3D G3DSA:3.40.309.10 275 470 8.8E-64 T 29-03-2018 MSG_RS01670 4f35f43c6a1a28636ee352fefd7cf9ac 247 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 230 5.8E-31 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MSG_RS01670 4f35f43c6a1a28636ee352fefd7cf9ac 247 SUPERFAMILY SSF51621 6 244 3.49E-58 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MSG_RS01670 4f35f43c6a1a28636ee352fefd7cf9ac 247 Gene3D G3DSA:3.20.20.60 4 245 6.6E-30 T 29-03-2018 MSG_RS05630 f7884d0972e8abb19238da3543ccff73 130 Pfam PF05305 Protein of unknown function (DUF732) 20 109 2.1E-23 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS09075 fb29e53e5d2f070c47e61ead9132d3e8 236 SUPERFAMILY SSF53474 9 214 4.25E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09075 fb29e53e5d2f070c47e61ead9132d3e8 236 Gene3D G3DSA:3.40.50.1820 1 232 1.1E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24600 b4f013ec8afa74ffc6740850371c3929 493 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 12 491 1.9E-97 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS24600 b4f013ec8afa74ffc6740850371c3929 493 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 10 89 5.3E-11 T 29-03-2018 IPR024962 YukD-like MSG_RS15880 bf2fb65b6629249be250ecedf4522b11 249 SUPERFAMILY SSF53474 40 231 7.69E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15880 bf2fb65b6629249be250ecedf4522b11 249 Gene3D G3DSA:3.40.50.1820 36 235 7.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS15880 bf2fb65b6629249be250ecedf4522b11 249 SMART SM01110 39 231 6.3E-89 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS15880 bf2fb65b6629249be250ecedf4522b11 249 Pfam PF01083 Cutinase 40 230 5.8E-44 T 29-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 MSG_RS06530 c4d3b34dab9d3d4ef6c34e4732389e0f 102 Pfam PF11829 Protein of unknown function (DUF3349) 7 93 4.2E-18 T 29-03-2018 IPR021784 Protein of unknown function DUF3349 MSG_RS21735 a6cb3990ed9e64e66317bcafb6722297 222 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 53 221 30.545 T 29-03-2018 IPR022939 Uncharacterised protein family UPF0678 MSG_RS21735 a6cb3990ed9e64e66317bcafb6722297 222 Gene3D G3DSA:2.40.128.20 23 222 1.1E-57 T 29-03-2018 IPR012674 Calycin MSG_RS21735 a6cb3990ed9e64e66317bcafb6722297 222 SUPERFAMILY SSF50814 56 219 8.12E-36 T 29-03-2018 IPR012674 Calycin MSG_RS21735 a6cb3990ed9e64e66317bcafb6722297 222 Pfam PF08768 Domain of unknown function (DUF1794) 61 219 1.4E-42 T 29-03-2018 IPR014878 Domain of unknown function DUF1794 MSG_RS24055 0013e566a2c17802d8ddb9349b702608 514 SUPERFAMILY SSF56317 228 472 4.97E-38 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS24055 0013e566a2c17802d8ddb9349b702608 514 Gene3D G3DSA:3.60.110.10 216 476 3.9E-40 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS24055 0013e566a2c17802d8ddb9349b702608 514 Pfam PF00795 Carbon-nitrogen hydrolase 233 471 1.1E-14 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MSG_RS02365 a9695d3512b525c75c2ebd29da864195 533 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 31 518 6.9E-180 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS02365 a9695d3512b525c75c2ebd29da864195 533 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 33 505 2.6E-167 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS20615 de598f658ce858ad9d10c03c4c89ff7b 62 Pfam PF14013 MT0933-like antitoxin protein 4 52 3.5E-19 T 29-03-2018 IPR028037 Antitoxin Rv0909/MT0933 MSG_RS16525 3ab58dadca1b15ffa8ef9d2625798fe9 491 Pfam PF02470 MlaD protein 42 116 9.7E-15 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS16525 3ab58dadca1b15ffa8ef9d2625798fe9 491 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 303 2.1E-65 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS07305 222c64ec121865adb5a9f639494acde3 182 SUPERFAMILY SSF110921 86 178 3.27E-12 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MSG_RS10020 904ba06b5a266c3f697f8c316dc85db6 444 SUPERFAMILY SSF51395 15 425 4.15E-92 T 29-03-2018 MSG_RS10020 904ba06b5a266c3f697f8c316dc85db6 444 PIRSF PIRSF500061 2 444 1.6E-166 T 29-03-2018 MSG_RS10020 904ba06b5a266c3f697f8c316dc85db6 444 PIRSF PIRSF006429 5 442 3.1E-147 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein MSG_RS10020 904ba06b5a266c3f697f8c316dc85db6 444 Pfam PF01645 Conserved region in glutamate synthase 84 335 1.1E-79 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MSG_RS10020 904ba06b5a266c3f697f8c316dc85db6 444 Gene3D G3DSA:3.20.20.70 5 434 1.8E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS05985 1f878210b494fa2ac85aafcf4d03799f 201 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 201 2.0E-29 T 29-03-2018 MSG_RS05985 1f878210b494fa2ac85aafcf4d03799f 201 Pfam PF17197 Domain of unknown function (DUF5134) 36 200 3.1E-29 T 29-03-2018 IPR033458 Protein of unknown function DUF5134 MSG_RS14825 5c8410c09476a07da5d8512ab62a28b1 279 Pfam PF02405 Permease MlaE 58 269 1.4E-52 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS19815 98aab4e75b0564852522d369a66b105e 307 Pfam PF02669 K+-transporting ATPase, c chain 11 103 3.5E-25 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MSG_RS19815 98aab4e75b0564852522d369a66b105e 307 Pfam PF02669 K+-transporting ATPase, c chain 229 300 2.1E-30 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MSG_RS19815 98aab4e75b0564852522d369a66b105e 307 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 7 302 27.632 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MSG_RS05790 6e6918e7d2f897ec4c8f64766c866aaf 228 Pfam PF00501 AMP-binding enzyme 27 80 2.5E-5 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MSG_RS05790 6e6918e7d2f897ec4c8f64766c866aaf 228 SUPERFAMILY SSF56801 21 226 3.66E-16 T 29-03-2018 MSG_RS05790 6e6918e7d2f897ec4c8f64766c866aaf 228 Gene3D G3DSA:3.40.50.980 162 228 3.2E-6 T 29-03-2018 MSG_RS05790 6e6918e7d2f897ec4c8f64766c866aaf 228 Gene3D G3DSA:3.40.50.980 1 161 5.0E-9 T 29-03-2018 MSG_RS05790 6e6918e7d2f897ec4c8f64766c866aaf 228 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 1 225 1.9E-69 T 29-03-2018 IPR017523 Conserved hypothetical protein CHP03089 MSG_RS04045 e8457c541d40aa5f641857d70bb83f8f 231 Gene3D G3DSA:3.90.226.10 1 228 3.2E-38 T 29-03-2018 MSG_RS04045 e8457c541d40aa5f641857d70bb83f8f 231 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 220 6.5E-27 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS04045 e8457c541d40aa5f641857d70bb83f8f 231 SUPERFAMILY SSF52096 4 222 4.81E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 SUPERFAMILY SSF51905 279 370 1.86E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 SUPERFAMILY SSF51905 6 172 1.86E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.3E-40 T 29-03-2018 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 Pfam PF01494 FAD binding domain 6 356 2.6E-62 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MSG_RS15990 ae1f93fdd98ac5a1834d7d70122e76d2 507 Gene3D G3DSA:3.50.50.60 1 402 3.3E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05190 5014c9ebd64711b44517f604d6a41446 341 Gene3D G3DSA:3.90.245.10 1 334 1.5E-96 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MSG_RS05190 5014c9ebd64711b44517f604d6a41446 341 SUPERFAMILY SSF53590 3 332 5.1E-85 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MSG_RS05190 5014c9ebd64711b44517f604d6a41446 341 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 326 1.6E-80 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MSG_RS11345 8b56cd89c8ffe122d26376e32df68f29 296 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 6 249 2.0E-75 T 29-03-2018 IPR014145 DNA ligase D, polymerase domain MSG_RS19360 524d147ca711968de32036b5c3c828e8 201 Gene3D G3DSA:1.10.10.10 1 73 7.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS20995 1639d90205ea3e62d1c981d2e739f1a8 211 Gene3D G3DSA:3.30.70.100 119 200 0.028 T 29-03-2018 MSG_RS15635 d11411b9e656f78c9de288fbff18442f 269 Pfam PF04072 Leucine carboxyl methyltransferase 17 169 2.8E-9 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS15635 d11411b9e656f78c9de288fbff18442f 269 PIRSF PIRSF028177 4 266 1.9E-61 T 29-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MSG_RS15635 d11411b9e656f78c9de288fbff18442f 269 SUPERFAMILY SSF53335 12 253 1.11E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS15635 d11411b9e656f78c9de288fbff18442f 269 Gene3D G3DSA:3.40.50.150 6 222 1.5E-27 T 29-03-2018 MSG_RS18685 377b30d2c71361eb104dca22ee5dd7d9 193 Pfam PF14041 LppP/LprE lipoprotein 103 181 3.7E-14 T 29-03-2018 IPR025971 LppP/LprE lipoprotein MSG_RS18685 377b30d2c71361eb104dca22ee5dd7d9 193 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 189 1.0E-73 T 29-03-2018 MSG_RS04655 c2b32cd545ffd2b5947d5621f0811150 308 SMART SM00849 56 281 3.8E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04655 c2b32cd545ffd2b5947d5621f0811150 308 Gene3D G3DSA:3.60.15.10 4 293 5.7E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04655 c2b32cd545ffd2b5947d5621f0811150 308 SUPERFAMILY SSF56281 38 297 6.81E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS04655 c2b32cd545ffd2b5947d5621f0811150 308 Pfam PF00753 Metallo-beta-lactamase superfamily 56 281 8.1E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13070 474e0b453150f832ea78c72375fe3070 110 Pfam PF04993 TfoX N-terminal domain 13 101 5.1E-16 T 29-03-2018 IPR007076 TfoX, N-terminal MSG_RS13070 474e0b453150f832ea78c72375fe3070 110 SUPERFAMILY SSF159894 6 102 6.54E-12 T 29-03-2018 MSG_RS13070 474e0b453150f832ea78c72375fe3070 110 Gene3D G3DSA:3.30.1460.30 3 105 2.0E-27 T 29-03-2018 MSG_RS17695 9bc2d531e97970d4ef3a746274cbe939 146 SUPERFAMILY SSF54427 30 140 3.58E-23 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS17695 9bc2d531e97970d4ef3a746274cbe939 146 Gene3D G3DSA:3.10.450.50 5 142 3.1E-17 T 29-03-2018 MSG_RS17695 9bc2d531e97970d4ef3a746274cbe939 146 Pfam PF12680 SnoaL-like domain 32 126 7.9E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS21975 a0fe3480856380043ec0395d9315a644 303 Gene3D G3DSA:3.40.50.1820 43 300 1.1E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21975 a0fe3480856380043ec0395d9315a644 303 SUPERFAMILY SSF53474 60 298 2.1E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21975 a0fe3480856380043ec0395d9315a644 303 Pfam PF00756 Putative esterase 97 262 9.7E-6 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS05310 0d216bac2a451c694b9ea764104d0bd5 94 Pfam PF11222 Protein of unknown function (DUF3017) 15 87 4.4E-23 T 29-03-2018 IPR021385 Protein of unknown function DUF3017 MSG_RS12725 95fc407a575c93f2c955d03aab96fefe 417 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 314 386 1.6E-7 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12725 95fc407a575c93f2c955d03aab96fefe 417 SUPERFAMILY SSF140459 3 174 2.01E-64 T 29-03-2018 MSG_RS12725 95fc407a575c93f2c955d03aab96fefe 417 Gene3D G3DSA:1.10.287.1060 22 106 2.6E-8 T 29-03-2018 MSG_RS12725 95fc407a575c93f2c955d03aab96fefe 417 Pfam PF00823 PPE family 6 162 5.5E-62 T 29-03-2018 IPR000030 PPE family MSG_RS04150 1b8468c54601235b6687f610e5984c7c 282 SUPERFAMILY SSF53474 2 275 6.68E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04150 1b8468c54601235b6687f610e5984c7c 282 Gene3D G3DSA:3.40.50.1820 1 281 3.9E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS04150 1b8468c54601235b6687f610e5984c7c 282 Pfam PF00561 alpha/beta hydrolase fold 7 261 6.9E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06215 07d08fa8f0a6c5d8ab7e01ea89bbf3a4 266 SUPERFAMILY SSF52540 5 254 2.83E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS06215 07d08fa8f0a6c5d8ab7e01ea89bbf3a4 266 Pfam PF13614 AAA domain 5 178 8.4E-55 T 29-03-2018 IPR025669 AAA domain MSG_RS06215 07d08fa8f0a6c5d8ab7e01ea89bbf3a4 266 Gene3D G3DSA:3.40.50.300 5 260 5.8E-56 T 29-03-2018 MSG_RS16030 c1254e5a93221c1a738bbfd2d38cfb07 288 SUPERFAMILY SSF51679 13 280 1.06E-54 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS16030 c1254e5a93221c1a738bbfd2d38cfb07 288 Pfam PF00296 Luciferase-like monooxygenase 11 220 2.8E-46 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS16030 c1254e5a93221c1a738bbfd2d38cfb07 288 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 32 257 6.8E-67 T 29-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted MSG_RS16030 c1254e5a93221c1a738bbfd2d38cfb07 288 Gene3D G3DSA:3.20.20.30 4 261 9.3E-60 T 29-03-2018 MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 Pfam PF00561 alpha/beta hydrolase fold 47 301 6.3E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 SUPERFAMILY SSF53474 14 314 5.31E-57 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 PRINTS PR00412 Epoxide hydrolase signature 289 311 1.1E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.1E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 PRINTS PR00412 Epoxide hydrolase signature 53 71 1.1E-10 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS23105 3e726dc6f02ea31b8ef9dc3b7d1d76e8 321 Gene3D G3DSA:3.40.50.1820 8 319 2.8E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS01425 591d80df059a2960449c273d0ac53b6b 197 Pfam PF00823 PPE family 10 157 8.8E-26 T 29-03-2018 IPR000030 PPE family MSG_RS01425 591d80df059a2960449c273d0ac53b6b 197 SUPERFAMILY SSF140459 9 156 1.57E-22 T 29-03-2018 MSG_RS08265 e3daf3a80a33644f4a4d866c4b639de7 388 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 70 297 8.8E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MSG_RS08265 e3daf3a80a33644f4a4d866c4b639de7 388 Pfam PF02481 DNA recombination-mediator protein A 73 289 2.1E-68 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MSG_RS08265 e3daf3a80a33644f4a4d866c4b639de7 388 Gene3D G3DSA:1.10.10.10 278 373 3.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08265 e3daf3a80a33644f4a4d866c4b639de7 388 SUPERFAMILY SSF102405 104 297 3.51E-32 T 29-03-2018 MSG_RS08265 e3daf3a80a33644f4a4d866c4b639de7 388 Gene3D G3DSA:3.40.50.450 122 270 2.9E-33 T 29-03-2018 MSG_RS13625 c677f0bbb5e493027fd7c6575f5cfb2b 347 SUPERFAMILY SSF53335 104 310 1.47E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS13625 c677f0bbb5e493027fd7c6575f5cfb2b 347 Pfam PF13649 Methyltransferase domain 149 245 1.3E-11 T 29-03-2018 MSG_RS13625 c677f0bbb5e493027fd7c6575f5cfb2b 347 Gene3D G3DSA:3.40.50.150 10 325 7.7E-22 T 29-03-2018 MSG_RS22225 889c763bfd36bf540bfdd2407a907107 336 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 4.3E-12 T 29-03-2018 IPR019933 DivIVA domain MSG_RS22225 889c763bfd36bf540bfdd2407a907107 336 Gene3D G3DSA:1.10.287.620 36 116 0.057 T 29-03-2018 MSG_RS22225 889c763bfd36bf540bfdd2407a907107 336 Gene3D G3DSA:1.10.287.620 117 336 2.2E-4 T 29-03-2018 MSG_RS22225 889c763bfd36bf540bfdd2407a907107 336 Pfam PF05103 DivIVA protein 3 108 3.2E-8 T 29-03-2018 IPR007793 DivIVA family MSG_RS12550 5f9938123abc6bc8d88b2e50efa7774c 78 SUPERFAMILY SSF51230 4 77 1.44E-13 T 29-03-2018 IPR011053 Single hybrid motif MSG_RS12550 5f9938123abc6bc8d88b2e50efa7774c 78 Gene3D G3DSA:2.40.50.100 3 78 9.4E-10 T 29-03-2018 MSG_RS12550 5f9938123abc6bc8d88b2e50efa7774c 78 Pfam PF00364 Biotin-requiring enzyme 6 75 1.2E-10 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 276 2.3E-34 T 29-03-2018 MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 SUPERFAMILY SSF51735 1 280 3.74E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 Gene3D G3DSA:3.40.50.720 1 280 7.6E-57 T 29-03-2018 MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 278 1.6E-99 T 29-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS12565 010242ccb7971a5ea117f6fdc28c2341 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MSG_RS15615 2bcc76df1b93b4e514e74ca7a96156cf 72 SUPERFAMILY SSF55008 3 63 6.68E-11 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS15615 2bcc76df1b93b4e514e74ca7a96156cf 72 Gene3D G3DSA:3.30.70.100 1 70 4.1E-12 T 29-03-2018 MSG_RS15615 2bcc76df1b93b4e514e74ca7a96156cf 72 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MSG_RS15615 2bcc76df1b93b4e514e74ca7a96156cf 72 Pfam PF00403 Heavy-metal-associated domain 5 49 2.9E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MSG_RS16060 4d7f822c58c8e31d15c01f2e9e3b190f 400 Gene3D G3DSA:3.40.640.10 41 268 1.7E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MSG_RS16060 4d7f822c58c8e31d15c01f2e9e3b190f 400 Gene3D G3DSA:3.90.1150.10 269 399 4.0E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MSG_RS16060 4d7f822c58c8e31d15c01f2e9e3b190f 400 SUPERFAMILY SSF53383 20 396 1.38E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MSG_RS16060 4d7f822c58c8e31d15c01f2e9e3b190f 400 Pfam PF00155 Aminotransferase class I and II 98 390 1.0E-29 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MSG_RS19760 3f36784fb84eea58daf236c90a10934f 283 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 197 280 9.7E-15 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS19760 3f36784fb84eea58daf236c90a10934f 283 Pfam PF00934 PE family 8 93 1.5E-8 T 29-03-2018 IPR000084 PE-PGRS family, N-terminal MSG_RS20030 c59e0242e70eeb0a52cbf097890cb0ec 307 Pfam PF00248 Aldo/keto reductase family 6 175 6.1E-28 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20030 c59e0242e70eeb0a52cbf097890cb0ec 307 SUPERFAMILY SSF51430 2 79 1.03E-35 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20030 c59e0242e70eeb0a52cbf097890cb0ec 307 SUPERFAMILY SSF51430 112 221 1.03E-35 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS20030 c59e0242e70eeb0a52cbf097890cb0ec 307 Gene3D G3DSA:3.20.20.100 1 302 5.1E-37 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MSG_RS17275 ed13180391b7eac771d8928827b3739c 155 Pfam PF17174 Domain of unknown function (DUF5130) 14 149 4.7E-61 T 29-03-2018 IPR033437 Protein of unknown function DUF5130 MSG_RS19890 616a0f9c637e363f48a2749677f16a07 118 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 8 118 1.3E-40 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MSG_RS19890 616a0f9c637e363f48a2749677f16a07 118 Pfam PF03960 ArsC family 11 117 4.1E-13 T 29-03-2018 IPR006660 Arsenate reductase-like MSG_RS19890 616a0f9c637e363f48a2749677f16a07 118 Gene3D G3DSA:3.40.30.10 6 118 5.8E-34 T 29-03-2018 MSG_RS19890 616a0f9c637e363f48a2749677f16a07 118 SUPERFAMILY SSF52833 7 118 1.17E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS12870 b4a26080e5b4a865c50430709c5689bf 111 SUPERFAMILY SSF50022 5 107 2.23E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12870 b4a26080e5b4a865c50430709c5689bf 111 Gene3D G3DSA:2.102.10.10 6 111 5.8E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS12870 b4a26080e5b4a865c50430709c5689bf 111 Pfam PF00355 Rieske [2Fe-2S] domain 6 93 2.5E-16 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS05945 385f85289408ab250cdae3b51eb99e57 380 Gene3D G3DSA:1.20.91.10 229 316 3.6E-6 T 29-03-2018 MSG_RS05945 385f85289408ab250cdae3b51eb99e57 380 Pfam PF00999 Sodium/hydrogen exchanger family 15 367 9.7E-40 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 Gene3D G3DSA:3.20.20.140 72 491 8.8E-39 T 29-03-2018 MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 Pfam PF07969 Amidohydrolase family 50 532 2.4E-77 T 29-03-2018 IPR013108 Amidohydrolase 3 MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51556 316 492 1.22E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51556 61 87 1.22E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51556 114 133 1.22E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51556 200 284 1.22E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 Gene3D G3DSA:2.30.40.10 1 71 1.8E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51338 491 533 3.12E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS03830 14e8007b5cfeee5e0842295406c6b724 534 SUPERFAMILY SSF51338 6 62 3.12E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MSG_RS10375 65f504021ca1b8ba3d3033b5f78cd795 155 Pfam PF10756 Bacterial PH domain 73 142 2.3E-24 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 MSG_RS00110 bd91b61f5fa67db6b31d6dacd79f6fe2 493 Gene3D G3DSA:3.90.1310.10 17 138 8.1E-15 T 29-03-2018 MSG_RS00110 bd91b61f5fa67db6b31d6dacd79f6fe2 493 Gene3D G3DSA:3.40.710.10 139 493 8.4E-87 T 29-03-2018 MSG_RS00110 bd91b61f5fa67db6b31d6dacd79f6fe2 493 SUPERFAMILY SSF56601 138 490 4.35E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS00110 bd91b61f5fa67db6b31d6dacd79f6fe2 493 Pfam PF00905 Penicillin binding protein transpeptidase domain 161 486 1.1E-77 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MSG_RS00085 96a1bc51580ffb985cef6eb8b43e6abe 93 Pfam PF06781 Cell division protein CrgA 1 93 2.8E-30 T 29-03-2018 IPR009619 Cell division protein CrgA MSG_RS00085 96a1bc51580ffb985cef6eb8b43e6abe 93 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 93 21.307 T 29-03-2018 IPR009619 Cell division protein CrgA MSG_RS12760 b976a5e50e31c504509ddaa5333052a8 228 SUPERFAMILY SSF50494 41 197 3.51E-19 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS12760 b976a5e50e31c504509ddaa5333052a8 228 Gene3D G3DSA:2.40.10.10 35 124 5.3E-12 T 29-03-2018 MSG_RS12760 b976a5e50e31c504509ddaa5333052a8 228 Gene3D G3DSA:2.40.10.10 127 208 1.1E-5 T 29-03-2018 MSG_RS09550 757618dcd8b9477d0b17b32a7af125b4 115 SUPERFAMILY SSF51182 19 105 1.5E-12 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS09550 757618dcd8b9477d0b17b32a7af125b4 115 Gene3D G3DSA:2.60.120.10 9 113 7.9E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS24485 7ee520ee442eb1cee59630b93b8f18ee 481 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 7 454 4.4E-154 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS24485 7ee520ee442eb1cee59630b93b8f18ee 481 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 5 466 1.4E-149 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS23890 ebfa6ed46c4fabe7b04bd83b760c757d 156 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 41 155 3.7E-37 T 29-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 MSG_RS06630 6cea9c6bd3e8e7f4f548d648f8903606 318 Gene3D G3DSA:3.40.50.1820 7 306 8.9E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS06630 6cea9c6bd3e8e7f4f548d648f8903606 318 Pfam PF00561 alpha/beta hydrolase fold 44 293 1.6E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS06630 6cea9c6bd3e8e7f4f548d648f8903606 318 SUPERFAMILY SSF53474 12 304 3.95E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS16395 dc8c721e1ae15e3a852e240aacd2fb43 457 Pfam PF01523 Putative modulator of DNA gyrase 26 320 1.3E-29 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MSG_RS16395 dc8c721e1ae15e3a852e240aacd2fb43 457 Gene3D G3DSA:3.30.2290.10 3 208 1.2E-28 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MSG_RS16395 dc8c721e1ae15e3a852e240aacd2fb43 457 SUPERFAMILY SSF111283 5 450 1.07E-58 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MSG_RS06315 197cd57625c447c2536537eee7f08f0e 446 Gene3D G3DSA:1.10.510.10 252 369 1.4E-6 T 29-03-2018 MSG_RS06315 197cd57625c447c2536537eee7f08f0e 446 Gene3D G3DSA:3.30.200.20 106 243 2.3E-24 T 29-03-2018 MSG_RS06315 197cd57625c447c2536537eee7f08f0e 446 Pfam PF03109 ABC1 family 117 231 4.3E-33 T 29-03-2018 IPR004147 UbiB domain MSG_RS06315 197cd57625c447c2536537eee7f08f0e 446 SUPERFAMILY SSF56112 194 308 1.26E-25 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS06315 197cd57625c447c2536537eee7f08f0e 446 SUPERFAMILY SSF56112 99 162 1.26E-25 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS03565 6f96d9996616ce4d0e7c9e72fe305a3b 142 Pfam PF14021 Tuberculosis necrotizing toxin 48 139 1.0E-16 T 29-03-2018 IPR025331 Tuberculosis necrotizing toxin MSG_RS11750 d22f7a4f2dd7d240ce40e79a1e2f7f93 275 Pfam PF02616 Segregation and condensation protein ScpA 36 260 5.8E-80 T 29-03-2018 IPR003768 Segregation and condensation protein A MSG_RS11750 d22f7a4f2dd7d240ce40e79a1e2f7f93 275 Gene3D G3DSA:1.10.10.580 188 259 1.1E-12 T 29-03-2018 MSG_RS13160 0681994e38b0ddb97668e29e003c792b 164 SUPERFAMILY SSF69118 11 152 3.26E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS13160 0681994e38b0ddb97668e29e003c792b 164 Pfam PF02627 Carboxymuconolactone decarboxylase family 20 101 1.6E-6 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13160 0681994e38b0ddb97668e29e003c792b 164 Gene3D G3DSA:1.20.1290.10 10 157 4.5E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS08905 e0876fd05cd16ffe24a136e0b60d25be 451 Pfam PF03993 Domain of Unknown Function (DUF349) 220 292 1.2E-18 T 29-03-2018 IPR007139 Protein of unknown function DUF349 MSG_RS08905 e0876fd05cd16ffe24a136e0b60d25be 451 Pfam PF03993 Domain of Unknown Function (DUF349) 297 369 3.0E-20 T 29-03-2018 IPR007139 Protein of unknown function DUF349 MSG_RS08905 e0876fd05cd16ffe24a136e0b60d25be 451 Pfam PF03993 Domain of Unknown Function (DUF349) 142 216 2.1E-13 T 29-03-2018 IPR007139 Protein of unknown function DUF349 MSG_RS16360 70d173ac76b2cb0fd066b7d9dfa29842 148 Pfam PF13643 Domain of unknown function (DUF4145) 30 118 5.6E-17 T 29-03-2018 IPR025285 Domain of unknown function DUF4145 MSG_RS12245 6d7aaa6fef64742803b2e6d14e6bd1ac 167 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 75 164 8.0E-25 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 252 276 7.2E-32 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 7.2E-32 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 171 195 7.2E-32 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 340 359 7.2E-32 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 392 418 7.2E-32 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 498 6.8E-163 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS06705 1f51c5fc08502f40ea573b324a75fb21 533 Pfam PF00361 Proton-conducting membrane transporter 134 433 1.5E-65 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS16940 99eb5cb2e27940a7a9f4436e3232d892 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 301 6.9E-75 T 29-03-2018 IPR007296 Domain of unknown function DUF403 MSG_RS22890 854289c5c051c3c127bf9d313642e366 187 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 41 179 1.1E-12 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS22890 854289c5c051c3c127bf9d313642e366 187 SUPERFAMILY SSF55961 40 180 3.87E-14 T 29-03-2018 MSG_RS22890 854289c5c051c3c127bf9d313642e366 187 Gene3D G3DSA:3.30.530.20 32 184 1.7E-15 T 29-03-2018 IPR023393 START-like domain MSG_RS17950 6d5e0c8f85b651cf56c3f11dd6ab2c81 90 Pfam PF04226 Transglycosylase associated protein 36 85 1.7E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MSG_RS21645 15abc537c1f9a04e5c41ef8b9f9e4ed7 352 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 60 295 9.2E-55 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS19450 4eaa27a25752f1cc3caa75be13a59844 122 Pfam PF10708 Protein of unknown function (DUF2510) 8 38 1.4E-11 T 29-03-2018 IPR018929 Domain of unknown function DUF2510 MSG_RS05845 5af0bb236e9f8534329906aaee0ebfd1 164 Pfam PF12005 Protein of unknown function (DUF3499) 22 161 2.6E-48 T 29-03-2018 IPR021888 Protein of unknown function DUF3499 MSG_RS00580 32ce250ef2c41d0e26e93560287c9908 191 Gene3D G3DSA:1.20.120.520 2 146 1.8E-15 T 29-03-2018 MSG_RS00580 32ce250ef2c41d0e26e93560287c9908 191 Pfam PF01814 Hemerythrin HHE cation binding domain 7 121 2.5E-11 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MSG_RS10550 24ca3b423b7e2f652f0856dca7d119f8 261 PIRSF PIRSF006648 7 259 4.3E-17 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS10550 24ca3b423b7e2f652f0856dca7d119f8 261 Pfam PF01061 ABC-2 type transporter 34 231 9.0E-12 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS10550 24ca3b423b7e2f652f0856dca7d119f8 261 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 38 261 6.8E-67 T 29-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 MSG_RS19895 2181638c6c38bf798ee3a350ae355c78 198 Pfam PF10738 Probable lipoprotein LpqN 28 196 9.6E-57 T 29-03-2018 IPR019674 Lipoprotein LpqT, predicted MSG_RS19895 2181638c6c38bf798ee3a350ae355c78 198 Gene3D G3DSA:3.40.1000.10 55 196 1.0E-15 T 29-03-2018 MSG_RS23745 19cab22e7e8a95422808951168d56dfe 415 SUPERFAMILY SSF56281 21 407 1.97E-69 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23745 19cab22e7e8a95422808951168d56dfe 415 Gene3D G3DSA:3.60.15.10 4 289 3.3E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23745 19cab22e7e8a95422808951168d56dfe 415 SMART SM00849 36 246 3.3E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23745 19cab22e7e8a95422808951168d56dfe 415 Pfam PF00753 Metallo-beta-lactamase superfamily 34 246 1.4E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS23745 19cab22e7e8a95422808951168d56dfe 415 Pfam PF14863 Alkyl sulfatase dimerisation 298 408 4.0E-15 T 29-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 MSG_RS00150 43b956b7cc2b40d7a2b80a0c950423b3 123 SUPERFAMILY SSF54427 5 113 1.13E-20 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS00150 43b956b7cc2b40d7a2b80a0c950423b3 123 Pfam PF12680 SnoaL-like domain 11 88 1.5E-14 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS00150 43b956b7cc2b40d7a2b80a0c950423b3 123 Gene3D G3DSA:3.10.450.50 2 118 4.1E-19 T 29-03-2018 MSG_RS12745 de3fbd8c3540b5496df6bd79af987fa7 236 PRINTS PR01837 MgtC/SapB protein signature 60 82 5.3E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MSG_RS12745 de3fbd8c3540b5496df6bd79af987fa7 236 PRINTS PR01837 MgtC/SapB protein signature 16 35 5.3E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MSG_RS12745 de3fbd8c3540b5496df6bd79af987fa7 236 PRINTS PR01837 MgtC/SapB protein signature 87 111 5.3E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MSG_RS12745 de3fbd8c3540b5496df6bd79af987fa7 236 PRINTS PR01837 MgtC/SapB protein signature 35 53 5.3E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MSG_RS12745 de3fbd8c3540b5496df6bd79af987fa7 236 Pfam PF02308 MgtC family 13 133 1.6E-32 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MSG_RS10010 9c6423db4213ee0a5057226e22222961 298 SUPERFAMILY SSF56235 117 296 1.16E-39 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS10010 9c6423db4213ee0a5057226e22222961 298 SUPERFAMILY SSF56235 2 45 1.16E-39 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS10010 9c6423db4213ee0a5057226e22222961 298 Gene3D G3DSA:3.60.20.10 2 298 4.2E-44 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MSG_RS10010 9c6423db4213ee0a5057226e22222961 298 Pfam PF13522 Glutamine amidotransferase domain 145 270 2.5E-15 T 29-03-2018 MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 105 115 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 Gene3D G3DSA:3.40.50.200 82 574 4.6E-60 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 Pfam PF00082 Subtilase family 337 555 8.6E-18 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 PRINTS PR00723 Subtilisin serine protease family (S8) signature 136 149 6.3E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 119 6.3E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 PRINTS PR00723 Subtilisin serine protease family (S8) signature 505 521 6.3E-9 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 SUPERFAMILY SSF52743 301 565 1.69E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS12695 f0447536d63cd790e65c96e611a87cd6 626 SUPERFAMILY SSF52743 82 153 1.69E-43 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS13995 d415402ef43898e76e334590a6fedc70 483 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 154 449 8.3E-59 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal MSG_RS13995 d415402ef43898e76e334590a6fedc70 483 Gene3D G3DSA:3.40.630.30 258 441 4.8E-5 T 29-03-2018 MSG_RS19005 06225d1806dc56c58363bd8bf62f5b17 116 Pfam PF05305 Protein of unknown function (DUF732) 16 104 1.7E-12 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS14010 51f7d059a46d345e054ee1e72d79b47a 599 Pfam PF00374 Nickel-dependent hydrogenase 181 577 4.7E-45 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MSG_RS14010 51f7d059a46d345e054ee1e72d79b47a 599 Pfam PF00374 Nickel-dependent hydrogenase 57 153 4.4E-18 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MSG_RS14010 51f7d059a46d345e054ee1e72d79b47a 599 Gene3D G3DSA:1.10.645.10 16 577 3.0E-131 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS14010 51f7d059a46d345e054ee1e72d79b47a 599 SUPERFAMILY SSF56762 18 577 1.83E-103 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS03260 27effddcff6112dcab2b53ce74326065 234 Pfam PF10099 Anti-sigma-K factor rskA 66 229 1.3E-20 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MSG_RS05425 0d0b12b0697ee96115415247800bcafb 409 Gene3D G3DSA:3.40.710.10 66 372 1.1E-54 T 29-03-2018 MSG_RS05425 0d0b12b0697ee96115415247800bcafb 409 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 95 316 2.2E-38 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MSG_RS05425 0d0b12b0697ee96115415247800bcafb 409 SUPERFAMILY SSF56601 82 337 1.29E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS05425 0d0b12b0697ee96115415247800bcafb 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 174 191 2.7E-6 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MSG_RS05425 0d0b12b0697ee96115415247800bcafb 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 137 2.7E-6 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MSG_RS01775 a83dda36100f6944f410573df3d300e7 233 Pfam PF06912 Protein of unknown function (DUF1275) 16 213 7.6E-30 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 MSG_RS16185 9a2719065f48634bc8d2a8f9e4c86cff 488 SUPERFAMILY SSF103473 247 449 1.07E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS16185 9a2719065f48634bc8d2a8f9e4c86cff 488 SUPERFAMILY SSF103473 11 201 1.07E-52 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS16185 9a2719065f48634bc8d2a8f9e4c86cff 488 Gene3D G3DSA:1.20.1250.20 9 198 3.3E-30 T 29-03-2018 MSG_RS16185 9a2719065f48634bc8d2a8f9e4c86cff 488 Pfam PF07690 Major Facilitator Superfamily 17 406 9.1E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MSG_RS16185 9a2719065f48634bc8d2a8f9e4c86cff 488 Gene3D G3DSA:1.20.1250.20 250 456 5.4E-19 T 29-03-2018 MSG_RS23830 96a4b705444796b3bf75e486c192f6de 315 Gene3D G3DSA:3.40.190.120 156 249 1.1E-27 T 29-03-2018 MSG_RS23830 96a4b705444796b3bf75e486c192f6de 315 Gene3D G3DSA:3.40.190.10 37 155 5.7E-17 T 29-03-2018 MSG_RS23830 96a4b705444796b3bf75e486c192f6de 315 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 42 305 4.6E-50 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 MSG_RS23830 96a4b705444796b3bf75e486c192f6de 315 SUPERFAMILY SSF53850 42 309 1.68E-45 T 29-03-2018 MSG_RS06435 f367713cd91aca3af3e40d8d35fcdcc1 110 Pfam PF05305 Protein of unknown function (DUF732) 12 105 1.1E-21 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS14595 0f8100cf1440b676667ced692198e22b 120 Pfam PF05305 Protein of unknown function (DUF732) 26 113 4.0E-14 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS07130 7711abf17bff064efad7a335770ca4e3 405 SUPERFAMILY SSF140459 2 174 4.18E-65 T 29-03-2018 MSG_RS07130 7711abf17bff064efad7a335770ca4e3 405 Pfam PF00823 PPE family 6 161 5.6E-63 T 29-03-2018 IPR000030 PPE family MSG_RS07130 7711abf17bff064efad7a335770ca4e3 405 Gene3D G3DSA:1.10.287.1060 22 102 6.7E-4 T 29-03-2018 MSG_RS22535 6c2956a77f8a879a12f3d700f1124116 252 SUPERFAMILY SSF52096 6 247 2.34E-55 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS22535 6c2956a77f8a879a12f3d700f1124116 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 209 3.6E-35 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS22535 6c2956a77f8a879a12f3d700f1124116 252 Gene3D G3DSA:3.90.226.10 2 252 7.0E-49 T 29-03-2018 MSG_RS14895 06ba8589960b6c65da8e7d2731929617 282 Pfam PF14494 Domain of unknown function (DUF4436) 35 277 2.9E-80 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS09230 c2e3204b6f3327d1ba15718ce827cdb5 313 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 32 268 9.3E-51 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MSG_RS09505 6177760a077c50ff5368ecc47d97ba08 294 Gene3D G3DSA:3.40.50.1110 16 213 2.9E-30 T 29-03-2018 MSG_RS09505 6177760a077c50ff5368ecc47d97ba08 294 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 28 199 2.3E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS09505 6177760a077c50ff5368ecc47d97ba08 294 SUPERFAMILY SSF52266 23 210 1.83E-33 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS15720 c31bfc6f83ab6c8f4c9e5ccf1dddf79b 444 Gene3D G3DSA:1.10.10.60 340 388 1.7E-6 T 29-03-2018 MSG_RS15720 c31bfc6f83ab6c8f4c9e5ccf1dddf79b 444 Pfam PF13556 PucR C-terminal helix-turn-helix domain 352 408 1.3E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MSG_RS18920 36b69a139a1158b3b9513f9a928ba59c 302 Gene3D G3DSA:3.40.50.1820 11 302 1.2E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18920 36b69a139a1158b3b9513f9a928ba59c 302 SUPERFAMILY SSF53474 14 296 3.02E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS18920 36b69a139a1158b3b9513f9a928ba59c 302 Pfam PF00561 alpha/beta hydrolase fold 38 132 8.5E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS05475 27a16bf82270a48f2b5723422a654cad 155 SUPERFAMILY SSF81343 27 152 3.05E-32 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS05475 27a16bf82270a48f2b5723422a654cad 155 Gene3D G3DSA:1.20.1300.10 14 151 4.6E-21 T 29-03-2018 MSG_RS05475 27a16bf82270a48f2b5723422a654cad 155 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 29 140 5.8E-17 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MSG_RS02690 09cc673f4b4735c89184c26e6690f205 556 Pfam PF00012 Hsp70 protein 100 338 1.5E-15 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MSG_RS02690 09cc673f4b4735c89184c26e6690f205 556 Gene3D G3DSA:3.30.420.40 163 321 1.6E-18 T 29-03-2018 MSG_RS02690 09cc673f4b4735c89184c26e6690f205 556 SUPERFAMILY SSF53067 155 338 1.7E-27 T 29-03-2018 MSG_RS02690 09cc673f4b4735c89184c26e6690f205 556 Gene3D G3DSA:3.30.420.40 1 162 9.9E-5 T 29-03-2018 MSG_RS12140 2d11422a3d533f56918cdadcc64e178b 405 Pfam PF13469 Sulfotransferase family 86 349 2.0E-35 T 29-03-2018 MSG_RS12140 2d11422a3d533f56918cdadcc64e178b 405 Gene3D G3DSA:3.40.50.300 67 404 2.3E-27 T 29-03-2018 MSG_RS12140 2d11422a3d533f56918cdadcc64e178b 405 SUPERFAMILY SSF52540 214 361 2.16E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS12140 2d11422a3d533f56918cdadcc64e178b 405 SUPERFAMILY SSF52540 60 134 2.16E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01090 eae6fe5ef5f31ff61573ec747699cd4d 123 Gene3D G3DSA:3.10.450.50 5 123 1.6E-13 T 29-03-2018 MSG_RS01090 eae6fe5ef5f31ff61573ec747699cd4d 123 SUPERFAMILY SSF54427 7 115 6.83E-17 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS01090 eae6fe5ef5f31ff61573ec747699cd4d 123 Pfam PF12680 SnoaL-like domain 8 110 9.2E-8 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS14360 ad5264201320a943c7df31a3c6c2484e 360 Pfam PF09375 Imelysin 107 347 3.3E-29 T 29-03-2018 IPR018976 Peptidase M75, Imelysin MSG_RS10970 5e6c74ec96f484fa3929bfbeae94801e 210 SUPERFAMILY SSF141488 134 208 2.88E-14 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MSG_RS10970 5e6c74ec96f484fa3929bfbeae94801e 210 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 138 204 2.0E-12 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MSG_RS10970 5e6c74ec96f484fa3929bfbeae94801e 210 Gene3D G3DSA:3.40.190.10 1 201 8.6E-5 T 29-03-2018 MSG_RS18755 b17aa88b681eafac2dba6d5bd42e7087 490 Pfam PF01547 Bacterial extracellular solute-binding protein 101 401 7.7E-29 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 MSG_RS18755 b17aa88b681eafac2dba6d5bd42e7087 490 Gene3D G3DSA:3.40.190.10 171 486 2.2E-41 T 29-03-2018 MSG_RS18755 b17aa88b681eafac2dba6d5bd42e7087 490 SUPERFAMILY SSF53850 106 311 2.04E-51 T 29-03-2018 MSG_RS18755 b17aa88b681eafac2dba6d5bd42e7087 490 SUPERFAMILY SSF53850 353 461 2.04E-51 T 29-03-2018 MSG_RS05075 636f2f580f1bb92e17baa6c7e27d9cfc 212 Gene3D G3DSA:2.60.40.200 41 181 3.3E-21 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS05075 636f2f580f1bb92e17baa6c7e27d9cfc 212 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 54 180 7.2E-19 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS05075 636f2f580f1bb92e17baa6c7e27d9cfc 212 SUPERFAMILY SSF49329 45 180 1.2E-26 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MSG_RS24345 f36a767168a56fae3e033af646966a3c 132 Gene3D G3DSA:1.10.260.40 1 92 2.1E-11 T 29-03-2018 MSG_RS20840 a54c0689638a2a3950b9fd894e1b959f 300 Gene3D G3DSA:3.20.20.370 9 299 4.9E-37 T 29-03-2018 MSG_RS20840 a54c0689638a2a3950b9fd894e1b959f 300 Pfam PF01522 Polysaccharide deacetylase 76 177 2.5E-5 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MSG_RS20840 a54c0689638a2a3950b9fd894e1b959f 300 SUPERFAMILY SSF88713 7 291 2.22E-53 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MSG_RS16665 2c7157b22a9c4bcff63727c1ee58144e 130 Gene3D G3DSA:1.10.10.10 1 82 9.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS16665 2c7157b22a9c4bcff63727c1ee58144e 130 Pfam PF01475 Ferric uptake regulator family 5 121 1.1E-36 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MSG_RS16665 2c7157b22a9c4bcff63727c1ee58144e 130 SUPERFAMILY SSF46785 4 126 3.77E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS22545 ddcd12b302ac1b8f3d1bf049bc67920b 249 SMART SM00882 8 208 0.0014 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MSG_RS22545 ddcd12b302ac1b8f3d1bf049bc67920b 249 SUPERFAMILY SSF100950 2 245 8.37E-50 T 29-03-2018 MSG_RS22545 ddcd12b302ac1b8f3d1bf049bc67920b 249 Gene3D G3DSA:3.40.1080.10 1 247 1.5E-28 T 29-03-2018 MSG_RS19140 fff3332945984210800c1aacd6e43e2f 440 Pfam PF09594 Glycosyltransferase family 87 101 332 3.8E-51 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MSG_RS15585 590d152aab736c0e77f723288cbcea16 271 Pfam PF02104 SURF1 family 23 225 9.7E-25 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MSG_RS06955 af07138bb6f515d80a9ba5c0ccb2c885 111 Pfam PF12587 Protein of unknown function (DUF3761) 33 111 4.5E-13 T 29-03-2018 IPR022236 Protein of unknown function DUF3761 MSG_RS23930 e050657844c797031ebaf6965250b202 331 Gene3D G3DSA:3.90.1200.10 103 288 6.3E-30 T 29-03-2018 MSG_RS23930 e050657844c797031ebaf6965250b202 331 Pfam PF01636 Phosphotransferase enzyme family 15 255 5.0E-37 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MSG_RS23930 e050657844c797031ebaf6965250b202 331 SUPERFAMILY SSF56112 7 323 2.21E-51 T 29-03-2018 IPR011009 Protein kinase-like domain MSG_RS23930 e050657844c797031ebaf6965250b202 331 Gene3D G3DSA:3.30.200.20 1 93 2.7E-15 T 29-03-2018 MSG_RS01020 0032785783c0a1e94f8c92213e4dc014 246 SUPERFAMILY SSF53335 64 237 4.8E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS01020 0032785783c0a1e94f8c92213e4dc014 246 Pfam PF08241 Methyltransferase domain 94 190 1.1E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS01020 0032785783c0a1e94f8c92213e4dc014 246 Gene3D G3DSA:3.40.50.150 52 244 5.6E-36 T 29-03-2018 MSG_RS16230 2de841543aee7aae22f2891f3223f4f2 166 Pfam PF11259 Protein of unknown function (DUF3060) 92 149 6.0E-11 T 29-03-2018 IPR021417 Protein of unknown function DUF3060 MSG_RS01160 8ac7b8d807f67fa2e1fb5fda573b85c4 667 Gene3D G3DSA:3.40.50.1110 444 667 1.3E-18 T 29-03-2018 MSG_RS01160 8ac7b8d807f67fa2e1fb5fda573b85c4 667 SUPERFAMILY SSF52266 453 666 6.78E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MSG_RS01160 8ac7b8d807f67fa2e1fb5fda573b85c4 667 Pfam PF01757 Acyltransferase family 20 374 2.6E-18 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS12660 7c9aaed1c830603d938e4069f3dfd293 404 Pfam PF00823 PPE family 5 161 2.5E-64 T 29-03-2018 IPR000030 PPE family MSG_RS12660 7c9aaed1c830603d938e4069f3dfd293 404 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 318 400 2.1E-14 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS12660 7c9aaed1c830603d938e4069f3dfd293 404 Gene3D G3DSA:1.10.287.1060 22 104 1.6E-7 T 29-03-2018 MSG_RS12660 7c9aaed1c830603d938e4069f3dfd293 404 SUPERFAMILY SSF140459 2 170 1.86E-62 T 29-03-2018 MSG_RS23680 5600a5fdc50a3d579bf93315f6962f9a 359 Gene3D G3DSA:3.40.50.720 3 128 1.7E-17 T 29-03-2018 MSG_RS23680 5600a5fdc50a3d579bf93315f6962f9a 359 SUPERFAMILY SSF51735 4 106 3.7E-9 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS02515 fa96a71ad436bd74fc206fc33b1a901d 277 Pfam PF00722 Glycosyl hydrolases family 16 84 224 9.1E-14 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 MSG_RS02515 fa96a71ad436bd74fc206fc33b1a901d 277 SUPERFAMILY SSF49899 33 277 8.04E-42 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MSG_RS02515 fa96a71ad436bd74fc206fc33b1a901d 277 Gene3D G3DSA:2.60.120.200 42 277 5.3E-40 T 29-03-2018 MSG_RS06295 10da88f4cce807bd287deb5508f0b2fc 209 Pfam PF14032 PknH-like extracellular domain 34 207 1.4E-18 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS01725 2acb3dde0e11c825a04eb10e9dd77da4 433 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 433 6.4E-104 T 29-03-2018 IPR024516 Mammalian cell entry, C-terminal MSG_RS01725 2acb3dde0e11c825a04eb10e9dd77da4 433 Pfam PF02470 MlaD protein 45 124 7.4E-14 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS01725 2acb3dde0e11c825a04eb10e9dd77da4 433 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 303 1.4E-76 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS10000 1c53d8301501bfbc422d8978f7e53cf5 505 Pfam PF13520 Amino acid permease 35 441 1.1E-49 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS10000 1c53d8301501bfbc422d8978f7e53cf5 505 PIRSF PIRSF006060 10 490 6.0E-54 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS10160 60d17a2a13808022109bf644302a5301 76 Pfam PF12838 4Fe-4S dicluster domain 20 66 1.8E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MSG_RS10160 60d17a2a13808022109bf644302a5301 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MSG_RS10160 60d17a2a13808022109bf644302a5301 76 SUPERFAMILY SSF54862 9 69 2.54E-16 T 29-03-2018 MSG_RS10160 60d17a2a13808022109bf644302a5301 76 Gene3D G3DSA:3.30.70.20 2 39 2.7E-8 T 29-03-2018 MSG_RS10160 60d17a2a13808022109bf644302a5301 76 Gene3D G3DSA:3.30.70.20 40 72 1.5E-6 T 29-03-2018 MSG_RS02510 84f20b362cb36c1154ca26c147b8db75 278 Gene3D G3DSA:2.60.120.200 38 278 1.3E-41 T 29-03-2018 MSG_RS02510 84f20b362cb36c1154ca26c147b8db75 278 SUPERFAMILY SSF49899 29 277 2.18E-42 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain MSG_RS02510 84f20b362cb36c1154ca26c147b8db75 278 Pfam PF00722 Glycosyl hydrolases family 16 89 208 1.0E-12 T 29-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 MSG_RS11650 b68c883da0c83009d384087185e3a3f2 271 PIRSF PIRSF006648 4 271 1.5E-22 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MSG_RS11650 b68c883da0c83009d384087185e3a3f2 271 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 47 270 9.4E-71 T 29-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 MSG_RS11650 b68c883da0c83009d384087185e3a3f2 271 Pfam PF01061 ABC-2 type transporter 30 233 2.6E-32 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS03875 c84dc1694cbb5160a0b4fc69fcaed55a 224 SUPERFAMILY SSF53335 26 197 1.24E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS03875 c84dc1694cbb5160a0b4fc69fcaed55a 224 Gene3D G3DSA:3.40.50.150 27 193 5.9E-26 T 29-03-2018 MSG_RS03875 c84dc1694cbb5160a0b4fc69fcaed55a 224 Pfam PF13649 Methyltransferase domain 50 144 1.0E-16 T 29-03-2018 MSG_RS20565 2d935f9bcad0ae6516e9b38b2853f9bd 61 Gene3D G3DSA:1.10.10.60 8 60 1.1E-4 T 29-03-2018 MSG_RS12305 fb2f517024b7e79a3fb1b54bdeda72d3 166 Gene3D G3DSA:3.10.129.10 6 166 1.7E-27 T 29-03-2018 MSG_RS12305 fb2f517024b7e79a3fb1b54bdeda72d3 166 SUPERFAMILY SSF54637 14 165 1.6E-22 T 29-03-2018 IPR029069 HotDog domain MSG_RS12305 fb2f517024b7e79a3fb1b54bdeda72d3 166 Pfam PF13452 N-terminal half of MaoC dehydratase 15 157 2.0E-18 T 29-03-2018 MSG_RS17080 4a5e011ff4540e618354b768624a52cb 181 Gene3D G3DSA:3.90.280.10 13 181 3.8E-34 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS17080 4a5e011ff4540e618354b768624a52cb 181 SUPERFAMILY SSF49777 31 181 1.31E-30 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS17080 4a5e011ff4540e618354b768624a52cb 181 Pfam PF01161 Phosphatidylethanolamine-binding protein 53 179 1.2E-23 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein MSG_RS08570 fc7e630c83c9f770d2d24d10124d74ed 186 Pfam PF08819 Domain of unknown function (DUF1802) 9 175 7.2E-58 T 29-03-2018 IPR014923 Protein of unknown function DUF1802 MSG_RS08570 fc7e630c83c9f770d2d24d10124d74ed 186 PIRSF PIRSF018957 1 186 5.0E-82 T 29-03-2018 IPR008307 Uncharacterised conserved protein UCP018957 MSG_RS08890 f794d9c394dceaff8d449a8f4be0da87 173 Hamap MF_01114 Regulatory protein RecX [recX]. 14 167 14.927 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MSG_RS08890 f794d9c394dceaff8d449a8f4be0da87 173 Gene3D G3DSA:1.10.10.10 115 165 2.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08890 f794d9c394dceaff8d449a8f4be0da87 173 Gene3D G3DSA:1.10.10.10 9 64 3.9E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08890 f794d9c394dceaff8d449a8f4be0da87 173 Gene3D G3DSA:1.10.10.10 65 110 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08890 f794d9c394dceaff8d449a8f4be0da87 173 Pfam PF02631 RecX family 41 160 6.6E-27 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MSG_RS14250 2962e3657cc0e5b0aa75b687430b42bb 290 Pfam PF02405 Permease MlaE 71 277 1.6E-49 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS16760 5ce27b5ced2a0a3a7e502320b386fdcc 75 SMART SM00923 4 54 6.5E-33 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS16760 5ce27b5ced2a0a3a7e502320b386fdcc 75 SUPERFAMILY SSF160582 3 70 1.57E-30 T 29-03-2018 MSG_RS16760 5ce27b5ced2a0a3a7e502320b386fdcc 75 Pfam PF03621 MbtH-like protein 4 54 2.9E-29 T 29-03-2018 IPR005153 MbtH-like protein MSG_RS16760 5ce27b5ced2a0a3a7e502320b386fdcc 75 Gene3D G3DSA:3.90.820.10 3 69 2.5E-34 T 29-03-2018 MSG_RS19750 4fb264fa8a648e0a243663d0290378c0 111 Pfam PF05305 Protein of unknown function (DUF732) 12 105 2.8E-21 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS00265 ccf47e82cd0597965f8487a07fe225cc 118 ProDom PD029828 TRANSMEMBRANE MEMBRANE ML0030 POSSIBLE RV0039C/MT0044 1 117 1.0E-31 T 29-03-2018 MSG_RS10695 97dc8c1f4185ecbe73a7d9f29688ee0b 144 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 2.1E-26 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain MSG_RS10695 97dc8c1f4185ecbe73a7d9f29688ee0b 144 Gene3D G3DSA:2.40.50.140 75 142 1.2E-15 T 29-03-2018 MSG_RS10695 97dc8c1f4185ecbe73a7d9f29688ee0b 144 SUPERFAMILY SSF141322 84 140 9.94E-6 T 29-03-2018 MSG_RS23565 66f8386b7be095313289da639095d664 116 Pfam PF05305 Protein of unknown function (DUF732) 13 107 7.0E-16 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS13580 4f0ee90a1baa0e81de22e0da62cdbb7a 224 Gene3D G3DSA:3.40.50.150 7 205 1.3E-17 T 29-03-2018 MSG_RS13580 4f0ee90a1baa0e81de22e0da62cdbb7a 224 SUPERFAMILY SSF53335 18 194 1.65E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS13580 4f0ee90a1baa0e81de22e0da62cdbb7a 224 Pfam PF13578 Methyltransferase domain 42 170 1.6E-22 T 29-03-2018 MSG_RS15675 dade02158cafb9668846f1c71600ef04 216 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 201 7.0E-15 T 29-03-2018 MSG_RS15675 dade02158cafb9668846f1c71600ef04 216 Pfam PF17197 Domain of unknown function (DUF5134) 37 214 1.9E-36 T 29-03-2018 IPR033458 Protein of unknown function DUF5134 MSG_RS10755 75a45c1ae61d30caa8e2fa952df0fa7c 256 Gene3D G3DSA:3.40.50.150 64 231 1.1E-10 T 29-03-2018 MSG_RS10755 75a45c1ae61d30caa8e2fa952df0fa7c 256 Pfam PF13578 Methyltransferase domain 92 197 4.7E-13 T 29-03-2018 MSG_RS10755 75a45c1ae61d30caa8e2fa952df0fa7c 256 SUPERFAMILY SSF53335 72 207 1.2E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS15055 99cbb3d02edc7763fd2b469073e55d98 96 Pfam PF02325 YGGT family 10 88 1.6E-11 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 MSG_RS14130 f01e1e7640e20c8aec4f256680629777 88 SUPERFAMILY SSF50118 1 77 1.24E-26 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MSG_RS14130 f01e1e7640e20c8aec4f256680629777 88 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 1.9E-25 T 29-03-2018 IPR015035 Domain of unknown function DUF1918 MSG_RS05315 d1134022933f5a106b7b549a478f39b9 197 Pfam PF05305 Protein of unknown function (DUF732) 26 119 4.6E-22 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS24155 bca32336cb40e276ff3adaa8c2f3f596 288 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 284 1.9E-112 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS24155 bca32336cb40e276ff3adaa8c2f3f596 288 SUPERFAMILY SSF53335 13 288 5.52E-71 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS24155 bca32336cb40e276ff3adaa8c2f3f596 288 Gene3D G3DSA:3.40.50.150 1 288 1.6E-53 T 29-03-2018 MSG_RS24155 bca32336cb40e276ff3adaa8c2f3f596 288 PIRSF PIRSF003085 2 288 7.1E-105 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MSG_RS18475 b9e636d81105f41bf07b3f56e9fe8cc4 678 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 176 200 8.0E-8 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18475 b9e636d81105f41bf07b3f56e9fe8cc4 678 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 8.0E-8 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18475 b9e636d81105f41bf07b3f56e9fe8cc4 678 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 243 267 8.0E-8 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS18475 b9e636d81105f41bf07b3f56e9fe8cc4 678 Pfam PF00361 Proton-conducting membrane transporter 139 422 1.9E-54 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS23040 fff451473aecb098a3ef1545620b799f 349 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 1 337 4.2E-109 T 29-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like MSG_RS23040 fff451473aecb098a3ef1545620b799f 349 Gene3D G3DSA:3.40.50.300 111 338 1.0E-22 T 29-03-2018 MSG_RS23040 fff451473aecb098a3ef1545620b799f 349 SUPERFAMILY SSF52540 114 318 1.82E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22480 b90e5a86664281273580d27c20471cda 133 Gene3D G3DSA:3.10.129.10 2 132 4.4E-20 T 29-03-2018 MSG_RS22480 b90e5a86664281273580d27c20471cda 133 SUPERFAMILY SSF54637 5 124 2.64E-17 T 29-03-2018 IPR029069 HotDog domain MSG_RS16690 82566c08489cd4285916eb8a8ebb4de1 297 Pfam PF05067 Manganese containing catalase 1 259 7.8E-69 T 29-03-2018 IPR007760 Manganese catalase MSG_RS16690 82566c08489cd4285916eb8a8ebb4de1 297 Gene3D G3DSA:1.20.1260.10 1 209 8.4E-70 T 29-03-2018 IPR012347 Ferritin-related MSG_RS16690 82566c08489cd4285916eb8a8ebb4de1 297 SUPERFAMILY SSF47240 1 261 8.25E-82 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS01415 13a3ce5931acdfa0f1412492c336f9fd 382 Gene3D G3DSA:3.20.20.140 25 374 1.8E-30 T 29-03-2018 MSG_RS01415 13a3ce5931acdfa0f1412492c336f9fd 382 Pfam PF04909 Amidohydrolase 104 362 8.1E-29 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS01415 13a3ce5931acdfa0f1412492c336f9fd 382 SUPERFAMILY SSF51556 74 369 9.64E-33 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS11870 f7cb68417256cbd524231233302302f9 143 Gene3D G3DSA:1.10.10.10 9 72 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS11870 f7cb68417256cbd524231233302302f9 143 Pfam PF03965 Penicillinase repressor 8 120 6.7E-24 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MSG_RS11870 f7cb68417256cbd524231233302302f9 143 SUPERFAMILY SSF46785 8 122 4.32E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS06325 2bf1caca91d98980b72e0c81b5db828e 283 SUPERFAMILY SSF101898 28 280 5.75E-41 T 29-03-2018 MSG_RS06325 2bf1caca91d98980b72e0c81b5db828e 283 Gene3D G3DSA:2.120.10.30 18 146 2.8E-14 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS06325 2bf1caca91d98980b72e0c81b5db828e 283 Gene3D G3DSA:2.120.10.30 147 282 4.4E-15 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS06325 2bf1caca91d98980b72e0c81b5db828e 283 Pfam PF01436 NHL repeat 255 279 2.5E-6 T 29-03-2018 IPR001258 NHL repeat GO:0005515 MSG_RS22435 cc3c4bbed15c3bcc34dd7af3708a8b1a 375 Gene3D G3DSA:2.60.120.600 47 149 5.5E-4 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS22435 cc3c4bbed15c3bcc34dd7af3708a8b1a 375 Gene3D G3DSA:2.60.120.600 222 350 4.7E-11 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 MSG_RS01195 ecffdefd816d37e547c638758bbdea5f 255 SUPERFAMILY SSF141523 132 253 3.92E-31 T 29-03-2018 MSG_RS01195 ecffdefd816d37e547c638758bbdea5f 255 Gene3D G3DSA:2.40.440.10 126 255 1.5E-27 T 29-03-2018 MSG_RS01195 ecffdefd816d37e547c638758bbdea5f 255 Pfam PF03734 L,D-transpeptidase catalytic domain 134 253 1.9E-19 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MSG_RS23025 af38f2ef97ca6e5b412475b10e49f21b 187 Pfam PF00482 Type II secretion system (T2SS), protein F 45 167 3.7E-14 T 29-03-2018 IPR018076 Type II secretion system F domain MSG_RS19030 b5e8303718b4ef884c1702d33bf90054 367 Pfam PF00823 PPE family 1 147 2.0E-50 T 29-03-2018 IPR000030 PPE family MSG_RS19030 b5e8303718b4ef884c1702d33bf90054 367 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 283 362 2.1E-9 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS19030 b5e8303718b4ef884c1702d33bf90054 367 SUPERFAMILY SSF140459 1 160 1.02E-50 T 29-03-2018 MSG_RS19030 b5e8303718b4ef884c1702d33bf90054 367 Gene3D G3DSA:1.10.287.1060 7 89 1.2E-5 T 29-03-2018 MSG_RS23965 c2a630338a6daf92f9783283a808c5f7 223 Pfam PF11139 Sap, sulfolipid-1-addressing protein 12 221 2.0E-57 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS04215 98dec438e5f083550435cbe183ac733d 493 PIRSF PIRSF006060 1 491 1.3E-44 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS04215 98dec438e5f083550435cbe183ac733d 493 Pfam PF13520 Amino acid permease 19 459 9.5E-28 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS19990 763fdea8cfce46415ccf697804424b37 486 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 340 470 8.0E-12 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MSG_RS19990 763fdea8cfce46415ccf697804424b37 486 Pfam PF01943 Polysaccharide biosynthesis protein 29 269 1.0E-16 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MSG_RS03080 c3842e74b6be8097c7f1c5a10ad820a0 144 Gene3D G3DSA:1.10.287.100 113 144 3.5E-10 T 29-03-2018 MSG_RS03080 c3842e74b6be8097c7f1c5a10ad820a0 144 Gene3D G3DSA:1.10.10.10 7 112 5.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03080 c3842e74b6be8097c7f1c5a10ad820a0 144 SUPERFAMILY SSF46785 13 143 5.27E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS03080 c3842e74b6be8097c7f1c5a10ad820a0 144 SMART SM00347 28 129 1.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS03080 c3842e74b6be8097c7f1c5a10ad820a0 144 Pfam PF01047 MarR family 35 91 2.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MSG_RS02540 5ea52afcf24e989b3f6b273e03d0e731 229 Pfam PF11139 Sap, sulfolipid-1-addressing protein 18 227 3.0E-55 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS10360 0129cabfc641e12d4885471ffb9fd9f8 109 Pfam PF05154 TM2 domain 40 92 3.4E-17 T 29-03-2018 IPR007829 TM2 domain MSG_RS09820 1468168f6e84245b3b198aac4753c6ba 312 Gene3D G3DSA:3.90.260.10 167 271 6.6E-5 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS09820 1468168f6e84245b3b198aac4753c6ba 312 SMART SM00460 186 260 1.3E-21 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS09820 1468168f6e84245b3b198aac4753c6ba 312 Pfam PF01841 Transglutaminase-like superfamily 157 258 5.9E-16 T 29-03-2018 IPR002931 Transglutaminase-like MSG_RS09820 1468168f6e84245b3b198aac4753c6ba 312 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 14 92 3.2E-22 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal MSG_RS09820 1468168f6e84245b3b198aac4753c6ba 312 SUPERFAMILY SSF54001 73 308 1.15E-37 T 29-03-2018 MSG_RS23070 9c7550d01fbb7dc2666770a7f17be39c 308 Gene3D G3DSA:1.10.3720.10 4 295 1.2E-34 T 29-03-2018 MSG_RS23070 9c7550d01fbb7dc2666770a7f17be39c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 1.8E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS23070 9c7550d01fbb7dc2666770a7f17be39c 308 SUPERFAMILY SSF161098 89 289 1.98E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS18360 7001ebb7b37c090e39e9d4694cef4690 222 Gene3D G3DSA:2.40.10.10 40 123 2.4E-14 T 29-03-2018 MSG_RS18360 7001ebb7b37c090e39e9d4694cef4690 222 SUPERFAMILY SSF50494 45 213 4.57E-20 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS02685 d571b08833474bf5088117325599c1ed 498 Gene3D G3DSA:3.40.50.300 28 374 1.2E-21 T 29-03-2018 MSG_RS02685 d571b08833474bf5088117325599c1ed 498 Pfam PF00350 Dynamin family 47 93 4.9E-8 T 29-03-2018 IPR022812 Dynamin superfamily MSG_RS02685 d571b08833474bf5088117325599c1ed 498 SUPERFAMILY SSF52540 41 232 7.04E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS22790 9776928b8d3cc0daee6325969e271538 263 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 3 245 2.1E-76 T 29-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative MSG_RS14075 97566732c8fa122483194f615cc6efed 224 SUPERFAMILY SSF52172 26 149 1.99E-20 T 29-03-2018 IPR011006 CheY-like superfamily MSG_RS14075 97566732c8fa122483194f615cc6efed 224 SMART SM00448 25 137 2.0E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS14075 97566732c8fa122483194f615cc6efed 224 Gene3D G3DSA:3.40.50.2300 18 218 5.8E-21 T 29-03-2018 MSG_RS14075 97566732c8fa122483194f615cc6efed 224 Pfam PF00072 Response regulator receiver domain 28 137 8.0E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MSG_RS13020 9269086e8b8a410466f3a6422c876939 92 Pfam PF04226 Transglycosylase associated protein 36 86 1.4E-8 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MSG_RS05915 288cb477a8e1febe9444c7ec63d192cb 591 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 329 590 8.9E-70 T 29-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal MSG_RS05915 288cb477a8e1febe9444c7ec63d192cb 591 Pfam PF10646 Sporulation and spore germination 174 296 1.5E-12 T 29-03-2018 IPR019606 GerMN domain MSG_RS05915 288cb477a8e1febe9444c7ec63d192cb 591 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 3 591 25.132 T 29-03-2018 IPR023959 Lipoprotein LpqB MSG_RS05915 288cb477a8e1febe9444c7ec63d192cb 591 Gene3D G3DSA:2.130.10.10 150 565 6.9E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MSG_RS05915 288cb477a8e1febe9444c7ec63d192cb 591 SMART SM00909 201 299 2.1E-14 T 29-03-2018 IPR019606 GerMN domain MSG_RS02575 f2dbf83f7a45ac24f0afdb242c5e829a 111 Pfam PF01638 HxlR-like helix-turn-helix 25 104 5.1E-8 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MSG_RS02575 f2dbf83f7a45ac24f0afdb242c5e829a 111 Gene3D G3DSA:1.10.10.10 10 110 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS02575 f2dbf83f7a45ac24f0afdb242c5e829a 111 SUPERFAMILY SSF46785 15 106 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08380 cbe8a7ca8c755fea35a6e6703988b276 288 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 221 2.4E-14 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MSG_RS19835 6c5949dd4b710a8271ee453983e8db22 162 Pfam PF04417 Protein of unknown function (DUF501) 25 144 7.3E-33 T 29-03-2018 IPR007511 Protein of unknown function DUF501 MSG_RS11620 2de61d12bfcba4577baab221397e3855 334 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 12 300 9.9E-59 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS11620 2de61d12bfcba4577baab221397e3855 334 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 136 205 1.8E-13 T 29-03-2018 IPR021368 Type VII secretion system protein EccE MSG_RS05155 32fcd0e2ca43e26614a67d5825f0ae03 278 Pfam PF13847 Methyltransferase domain 46 153 9.6E-23 T 29-03-2018 IPR025714 Methyltransferase domain MSG_RS05155 32fcd0e2ca43e26614a67d5825f0ae03 278 SUPERFAMILY SSF53335 12 171 1.01E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05155 32fcd0e2ca43e26614a67d5825f0ae03 278 Gene3D G3DSA:3.40.50.150 16 262 2.8E-32 T 29-03-2018 MSG_RS01270 c366f0f8691caaed949eec49c6394ddc 275 SUPERFAMILY SSF52540 9 230 3.15E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MSG_RS01270 c366f0f8691caaed949eec49c6394ddc 275 Gene3D G3DSA:3.40.50.300 5 274 1.4E-66 T 29-03-2018 MSG_RS01270 c366f0f8691caaed949eec49c6394ddc 275 SMART SM00382 33 218 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MSG_RS01270 c366f0f8691caaed949eec49c6394ddc 275 Pfam PF00005 ABC transporter 25 167 8.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MSG_RS13760 d617870edaf61aaa6afcf2647f86879a 103 Gene3D G3DSA:2.30.30.110 2 102 7.4E-20 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MSG_RS13760 d617870edaf61aaa6afcf2647f86879a 103 SUPERFAMILY SSF50118 2 103 1.8E-16 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MSG_RS13760 d617870edaf61aaa6afcf2647f86879a 103 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 101 3.5E-14 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MSG_RS23810 ed18c4ccde0490580903e7c131a3b5dc 198 SUPERFAMILY SSF159275 10 198 8.89E-53 T 29-03-2018 MSG_RS23810 ed18c4ccde0490580903e7c131a3b5dc 198 Pfam PF06475 Putative glycolipid-binding 15 197 7.6E-52 T 29-03-2018 IPR009467 Putative glycolipid-binding protein MSG_RS08200 c3b3263b934a3bfbfc2c7839856aefa3 80 SUPERFAMILY SSF54814 19 63 5.82E-8 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MSG_RS08200 c3b3263b934a3bfbfc2c7839856aefa3 80 Gene3D G3DSA:3.30.300.20 2 77 1.7E-13 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MSG_RS08200 c3b3263b934a3bfbfc2c7839856aefa3 80 Hamap MF_00088 UPF0109 protein . 5 76 20.905 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 MSG_RS08200 c3b3263b934a3bfbfc2c7839856aefa3 80 Pfam PF13083 KH domain 7 67 4.9E-20 T 29-03-2018 MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 SUPERFAMILY SSF46689 2 83 1.18E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 7.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 Gene3D G3DSA:1.10.357.10 1 226 1.4E-31 T 29-03-2018 MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 SUPERFAMILY SSF48498 81 217 1.4E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS19965 c1a330c6f32439682ff32bfe37d20183 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.6E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS11585 a1da6bb476a33d6dd1e207bef3a6d7d7 97 Gene3D G3DSA:1.10.287.1060 1 97 4.4E-12 T 29-03-2018 MSG_RS11585 a1da6bb476a33d6dd1e207bef3a6d7d7 97 Pfam PF06013 Proteins of 100 residues with WXG 10 87 6.5E-7 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS11585 a1da6bb476a33d6dd1e207bef3a6d7d7 97 SUPERFAMILY SSF140453 4 93 1.83E-9 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS04935 8bff78973710d3dde99a3fe2b1eb0953 347 Gene3D G3DSA:3.20.20.30 1 344 4.1E-64 T 29-03-2018 MSG_RS04935 8bff78973710d3dde99a3fe2b1eb0953 347 SUPERFAMILY SSF51679 1 340 3.53E-64 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS04935 8bff78973710d3dde99a3fe2b1eb0953 347 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 325 1.0E-159 T 29-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c MSG_RS04935 8bff78973710d3dde99a3fe2b1eb0953 347 Pfam PF00296 Luciferase-like monooxygenase 6 320 5.5E-73 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS09795 170a530082e1b149570dc5b14f3adb01 319 Gene3D G3DSA:3.40.50.1820 6 315 2.1E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09795 170a530082e1b149570dc5b14f3adb01 319 SUPERFAMILY SSF53474 43 299 2.63E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS09795 170a530082e1b149570dc5b14f3adb01 319 Pfam PF07859 alpha/beta hydrolase fold 88 294 3.3E-59 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MSG_RS17095 d1841f413dc17e342d56d9758bc98f6c 153 Pfam PF05305 Protein of unknown function (DUF732) 30 122 1.7E-11 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS24615 7814267697f56569e5444f451f83ec5b 97 Gene3D G3DSA:1.10.287.1060 1 96 2.3E-7 T 29-03-2018 MSG_RS24615 7814267697f56569e5444f451f83ec5b 97 ProDom PD065399 ESAT-6-LIKE ESAT-6 ORF3890C LIKE 1 95 7.0E-18 T 29-03-2018 IPR020167 ESAT-6-like protein EsxC MSG_RS24615 7814267697f56569e5444f451f83ec5b 97 SUPERFAMILY SSF140453 5 95 2.35E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24615 7814267697f56569e5444f451f83ec5b 97 Pfam PF06013 Proteins of 100 residues with WXG 5 88 4.8E-8 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS20010 b2522ab6547fff204e4df821d17998dc 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 4.2E-48 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MSG_RS20010 b2522ab6547fff204e4df821d17998dc 317 Gene3D G3DSA:3.40.50.720 2 190 2.5E-29 T 29-03-2018 MSG_RS20010 b2522ab6547fff204e4df821d17998dc 317 Gene3D G3DSA:3.90.25.10 191 315 5.1E-36 T 29-03-2018 MSG_RS20010 b2522ab6547fff204e4df821d17998dc 317 SUPERFAMILY SSF51735 2 312 1.17E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS08825 fa73f49591043229fea36c6d200dbad7 290 SUPERFAMILY SSF53335 8 283 2.02E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS08825 fa73f49591043229fea36c6d200dbad7 290 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 270 1.3E-68 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS08825 fa73f49591043229fea36c6d200dbad7 290 Gene3D G3DSA:3.40.50.150 7 283 1.5E-35 T 29-03-2018 MSG_RS08825 fa73f49591043229fea36c6d200dbad7 290 Pfam PF04072 Leucine carboxyl methyltransferase 11 193 8.5E-38 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 79 170 1.4E-7 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 Gene3D G3DSA:1.10.10.60 3 68 2.7E-12 T 29-03-2018 MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 Gene3D G3DSA:1.10.357.10 69 193 7.0E-18 T 29-03-2018 MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 62 2.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 SUPERFAMILY SSF48498 77 188 2.74E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS16025 4e4f9a0bf9f0109daab9aa190880f228 193 SUPERFAMILY SSF46689 9 74 1.18E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS03405 b8c3ac0fe81be76bd6d8463aed34257e 87 Pfam PF10724 Protein of unknown function (DUF2516) 1 84 9.2E-27 T 29-03-2018 IPR019662 Protein of unknown function DUF2516 MSG_RS24320 5a5d886f6e8e104949c31631b527e6bc 343 Pfam PF14219 Domain of unknown function (DUF4328) 153 305 6.3E-24 T 29-03-2018 IPR025565 Domain of unknown function DUF4328 MSG_RS21485 78f7e906298a0406d3b08af0d63f5e66 409 SUPERFAMILY SSF55874 267 403 1.96E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21485 78f7e906298a0406d3b08af0d63f5e66 409 Gene3D G3DSA:3.30.565.10 271 409 1.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS21125 e575da4305d70a4b3cdd1a7ce4ad4b9f 282 Pfam PF02405 Permease MlaE 65 268 8.3E-52 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS11055 6e1c98a755b69306aaf120a26098da5e 270 Gene3D G3DSA:3.90.1720.10 33 179 3.1E-27 T 29-03-2018 MSG_RS11055 6e1c98a755b69306aaf120a26098da5e 270 SUPERFAMILY SSF54001 36 161 1.32E-22 T 29-03-2018 MSG_RS11055 6e1c98a755b69306aaf120a26098da5e 270 Pfam PF00877 NlpC/P60 family 52 164 1.9E-25 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MSG_RS24355 93d93d3214ce43c7d4e971bb6eb244ec 222 Pfam PF07987 Domain of unkown function (DUF1775) 35 168 2.1E-32 T 29-03-2018 IPR012533 YcnI-like MSG_RS07175 84d210ccf9ace89c7315e20e69b12740 117 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 109 1.1E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MSG_RS07175 84d210ccf9ace89c7315e20e69b12740 117 SUPERFAMILY SSF54593 8 114 9.67E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS07175 84d210ccf9ace89c7315e20e69b12740 117 Gene3D G3DSA:3.10.180.10 2 117 2.4E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS24180 11e1240afb41a6fea433cd0643a28e9f 300 Pfam PF00756 Putative esterase 45 294 2.2E-50 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS24180 11e1240afb41a6fea433cd0643a28e9f 300 SUPERFAMILY SSF53474 38 295 3.46E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS24180 11e1240afb41a6fea433cd0643a28e9f 300 Gene3D G3DSA:3.40.50.1820 29 295 3.7E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS14565 8c8632c3f6947daf2fbdb72bcfe88016 176 Pfam PF04186 FxsA cytoplasmic membrane protein 5 105 4.6E-16 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MSG_RS08190 ef99aa3b4cb7a887a477d1270ceb7016 139 Gene3D G3DSA:3.10.450.50 2 137 1.7E-30 T 29-03-2018 MSG_RS08190 ef99aa3b4cb7a887a477d1270ceb7016 139 Pfam PF13577 SnoaL-like domain 6 129 6.0E-28 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS08190 ef99aa3b4cb7a887a477d1270ceb7016 139 SUPERFAMILY SSF54427 4 135 6.11E-34 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS23725 155c0cba6e9aa995fba846efcf0c1045 404 Gene3D G3DSA:2.102.10.10 64 181 0.011 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS18150 63fcc8b11accbeeb931930c12cf62cff 223 Gene3D G3DSA:3.40.1350.10 101 219 5.0E-4 T 29-03-2018 MSG_RS18150 63fcc8b11accbeeb931930c12cf62cff 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.826 T 29-03-2018 IPR002793 Endonuclease NucS MSG_RS18150 63fcc8b11accbeeb931930c12cf62cff 223 Pfam PF01939 Endonuclease NucS 1 223 1.8E-98 T 29-03-2018 IPR002793 Endonuclease NucS MSG_RS04540 2579ea5f7e75bd7004763321e74ca192 278 Pfam PF14494 Domain of unknown function (DUF4436) 34 276 2.1E-98 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS13560 07bc0876c6f2e1e46659b0eb07b0ef50 213 Pfam PF02627 Carboxymuconolactone decarboxylase family 68 133 1.4E-7 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS13560 07bc0876c6f2e1e46659b0eb07b0ef50 213 SUPERFAMILY SSF69118 1 186 1.54E-33 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS13560 07bc0876c6f2e1e46659b0eb07b0ef50 213 Gene3D G3DSA:1.20.1290.10 42 189 4.1E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS17900 ad73866ca354387ac50d7c8ba245cc80 129 Gene3D G3DSA:1.20.1290.10 2 124 1.2E-23 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS17900 ad73866ca354387ac50d7c8ba245cc80 129 SUPERFAMILY SSF69118 9 110 2.09E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS17900 ad73866ca354387ac50d7c8ba245cc80 129 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 91 4.4E-15 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS17900 ad73866ca354387ac50d7c8ba245cc80 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 26 106 7.5E-22 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS21515 0bf71cdb98dcf8bd330c663ffbe5da91 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 250 3.7E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MSG_RS21515 0bf71cdb98dcf8bd330c663ffbe5da91 255 SUPERFAMILY SSF52096 3 251 3.08E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS21515 0bf71cdb98dcf8bd330c663ffbe5da91 255 Gene3D G3DSA:3.90.226.10 2 255 5.0E-57 T 29-03-2018 MSG_RS19670 b09a78a01ff37ee72c09941186676aa0 362 Gene3D G3DSA:3.90.226.10 7 347 1.9E-88 T 29-03-2018 MSG_RS19670 b09a78a01ff37ee72c09941186676aa0 362 Pfam PF16113 Enoyl-CoA hydratase/isomerase 33 353 4.7E-121 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MSG_RS19670 b09a78a01ff37ee72c09941186676aa0 362 SUPERFAMILY SSF52096 262 339 1.72E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS19670 b09a78a01ff37ee72c09941186676aa0 362 SUPERFAMILY SSF52096 24 206 1.72E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MSG_RS03790 9584ddae4ab5ba73cea7c077137bdbdf 403 Pfam PF01384 Phosphate transporter family 22 321 5.8E-76 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MSG_RS03300 0dfe5a9db54d20e2ddc5853179f6c432 150 Pfam PF16877 Domain of unknown function (DUF5078) 33 149 7.1E-57 T 29-03-2018 IPR031702 Protein of unknown function DUF5078 MSG_RS20630 b2a9d4ccee0a861135a58d82aba4ee7e 372 Pfam PF12706 Beta-lactamase superfamily domain 124 321 1.6E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20630 b2a9d4ccee0a861135a58d82aba4ee7e 372 SUPERFAMILY SSF56281 106 182 6.68E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20630 b2a9d4ccee0a861135a58d82aba4ee7e 372 SUPERFAMILY SSF56281 210 362 6.68E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS20630 b2a9d4ccee0a861135a58d82aba4ee7e 372 PIRSF PIRSF038896 1 369 2.5E-102 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 MSG_RS20630 b2a9d4ccee0a861135a58d82aba4ee7e 372 Gene3D G3DSA:3.60.15.10 99 362 1.2E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 PRINTS PR00163 Rubredoxin signature 3 19 3.8E-5 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 PRINTS PR00163 Rubredoxin signature 33 49 3.8E-5 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 Gene3D G3DSA:2.20.28.10 1 54 1.1E-20 T 29-03-2018 MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 Pfam PF00301 Rubredoxin 4 50 1.3E-19 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 MSG_RS05880 72aa3e3c7ec6167cdeeb43e67cf63630 57 SUPERFAMILY SSF57802 1 54 5.5E-18 T 29-03-2018 MSG_RS24610 45a89865053ed994b6ee03a9c7ca1fe7 278 Pfam PF14011 EspG family 5 259 3.1E-40 T 29-03-2018 IPR025734 EspG family MSG_RS05615 527790d1d17de012ec606c89b6843e7c 207 Gene3D G3DSA:3.10.180.10 28 139 8.6E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MSG_RS03480 87844cf723b506f33da60d0ed04c2c49 423 SUPERFAMILY SSF140459 2 174 1.07E-61 T 29-03-2018 MSG_RS03480 87844cf723b506f33da60d0ed04c2c49 423 Gene3D G3DSA:1.10.287.1060 22 105 2.2E-6 T 29-03-2018 MSG_RS03480 87844cf723b506f33da60d0ed04c2c49 423 Pfam PF00823 PPE family 6 161 2.3E-61 T 29-03-2018 IPR000030 PPE family MSG_RS12105 577c841ec1f0e20896f38fa8488747f4 277 Pfam PF06966 Protein of unknown function (DUF1295) 31 256 4.3E-42 T 29-03-2018 IPR010721 Protein of unknown function DUF1295 MSG_RS24580 335be400cf27258f961be26a01d5d829 450 PRINTS PR00723 Subtilisin serine protease family (S8) signature 332 348 3.4E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24580 335be400cf27258f961be26a01d5d829 450 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 102 3.4E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24580 335be400cf27258f961be26a01d5d829 450 PRINTS PR00723 Subtilisin serine protease family (S8) signature 119 132 3.4E-12 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related MSG_RS24580 335be400cf27258f961be26a01d5d829 450 SUPERFAMILY SSF52743 66 391 5.24E-60 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24580 335be400cf27258f961be26a01d5d829 450 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 73 447 4.3E-114 T 29-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin MSG_RS24580 335be400cf27258f961be26a01d5d829 450 Gene3D G3DSA:3.40.50.200 41 396 2.4E-64 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS24580 335be400cf27258f961be26a01d5d829 450 Pfam PF00082 Subtilase family 83 382 7.9E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MSG_RS13045 8573992792d9a7c09824abf66f70f398 303 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 300 15.638 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MSG_RS13045 8573992792d9a7c09824abf66f70f398 303 Pfam PF02673 Bacitracin resistance protein BacA 10 294 6.3E-77 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MSG_RS18760 698d9c9c5504a7ada66fd98f0ac92de3 175 Gene3D G3DSA:1.20.1250.20 1 150 1.3E-4 T 29-03-2018 MSG_RS21740 039da24508c92eaebd4ba854a7094242 791 Gene3D G3DSA:3.40.50.720 142 339 9.1E-6 T 29-03-2018 MSG_RS14690 d72199ae5f603d5aefeb2a555668f5a8 222 Gene3D G3DSA:1.20.1250.20 2 90 7.2E-4 T 29-03-2018 MSG_RS20785 4c1d2483e858fc091a0ce257ece94069 134 PIRSF PIRSF028777 1 129 1.5E-48 T 29-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 MSG_RS20785 4c1d2483e858fc091a0ce257ece94069 134 Pfam PF03733 Inner membrane component domain 68 118 4.6E-17 T 29-03-2018 IPR005185 Inner membrane component domain MSG_RS20785 4c1d2483e858fc091a0ce257ece94069 134 Pfam PF03733 Inner membrane component domain 4 54 8.5E-17 T 29-03-2018 IPR005185 Inner membrane component domain MSG_RS10690 f7071c1cf8a2e7c72cbe0f93d2b2fa97 312 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 1 291 3.0E-114 T 29-03-2018 MSG_RS11245 149243923e502e0756f35a08410cb563 127 Pfam PF05154 TM2 domain 56 108 5.2E-13 T 29-03-2018 IPR007829 TM2 domain MSG_RS17805 d8366f1ca5b95f49d1177da1f49dfec0 131 Pfam PF00355 Rieske [2Fe-2S] domain 19 118 2.4E-13 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17805 d8366f1ca5b95f49d1177da1f49dfec0 131 Gene3D G3DSA:2.102.10.10 15 131 2.5E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS17805 d8366f1ca5b95f49d1177da1f49dfec0 131 SUPERFAMILY SSF50022 16 130 1.31E-28 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MSG_RS19270 280635d4b4004b3cb91ee8bd28658115 494 SUPERFAMILY SSF53720 9 492 8.12E-139 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MSG_RS19270 280635d4b4004b3cb91ee8bd28658115 494 Pfam PF00171 Aldehyde dehydrogenase family 21 489 7.2E-142 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MSG_RS19270 280635d4b4004b3cb91ee8bd28658115 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MSG_RS19270 280635d4b4004b3cb91ee8bd28658115 494 Gene3D G3DSA:3.40.309.10 278 474 1.9E-61 T 29-03-2018 MSG_RS19270 280635d4b4004b3cb91ee8bd28658115 494 Gene3D G3DSA:3.40.605.10 1 277 6.8E-72 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MSG_RS15975 2b260d9aeeec3e8a27b626b8c222824d 528 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 6 524 2.5E-184 T 29-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 MSG_RS15975 2b260d9aeeec3e8a27b626b8c222824d 528 Pfam PF00999 Sodium/hydrogen exchanger family 7 405 6.0E-66 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MSG_RS16845 771e8cde7a31d8d67a5dbfa5b43f3b1a 413 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 16 403 9.5E-106 T 29-03-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily MSG_RS10275 6872ded20a2e8e2780311d94a1ad7c75 193 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 101 3.9E-11 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS10275 6872ded20a2e8e2780311d94a1ad7c75 193 Gene3D G3DSA:2.30.110.10 1 135 1.7E-21 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS10275 6872ded20a2e8e2780311d94a1ad7c75 193 SUPERFAMILY SSF50475 8 131 5.58E-13 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13195 742effd4c42fd69e6da5349bcc7da4e2 151 SUPERFAMILY SSF55961 3 150 1.61E-23 T 29-03-2018 MSG_RS13195 742effd4c42fd69e6da5349bcc7da4e2 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 149 1.7E-19 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS13195 742effd4c42fd69e6da5349bcc7da4e2 151 Gene3D G3DSA:3.30.530.20 2 151 4.4E-29 T 29-03-2018 IPR023393 START-like domain MSG_RS22355 6ac690d844331928e0ba19eda3e3d5ca 429 Pfam PF01757 Acyltransferase family 24 356 1.7E-15 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS23800 9acb52ed9fcc8a572a3072989f299dbb 173 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 18 166 1.3E-50 T 29-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative MSG_RS23300 aac65069732086328134ba9f172be7a4 440 Pfam PF01882 Protein of unknown function DUF58 187 280 1.2E-18 T 29-03-2018 IPR002881 Domain of unknown function DUF58 MSG_RS23300 aac65069732086328134ba9f172be7a4 440 Gene3D G3DSA:3.40.50.410 199 416 2.7E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A MSG_RS09240 8cbca5f4b0e4d0e8a1cc56055c7e9c0b 177 Pfam PF05305 Protein of unknown function (DUF732) 82 172 3.0E-16 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS21550 f0f297bc45ad7c7406f80484aafba972 318 Pfam PF00296 Luciferase-like monooxygenase 3 283 1.1E-50 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS21550 f0f297bc45ad7c7406f80484aafba972 318 Gene3D G3DSA:3.20.20.30 1 317 6.2E-48 T 29-03-2018 MSG_RS21550 f0f297bc45ad7c7406f80484aafba972 318 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 21 286 5.8E-106 T 29-03-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted MSG_RS21550 f0f297bc45ad7c7406f80484aafba972 318 SUPERFAMILY SSF51679 10 292 4.12E-49 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS07690 8245c1a9c1cb175bb9934d4e8da32ce1 252 Pfam PF14494 Domain of unknown function (DUF4436) 82 247 1.1E-59 T 29-03-2018 IPR027948 Protein of unknown function (DUF4436) MSG_RS15895 3459485f823e9c7777b2f91e5d4f10ce 184 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 102 1.5E-8 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MSG_RS15895 3459485f823e9c7777b2f91e5d4f10ce 184 SUPERFAMILY SSF69118 1 171 6.42E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS15895 3459485f823e9c7777b2f91e5d4f10ce 184 Gene3D G3DSA:1.20.1290.10 26 177 1.8E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MSG_RS16265 87781e60eaa419e6095e2cfe93d1a95e 172 Gene3D G3DSA:3.10.450.50 66 172 1.7E-5 T 29-03-2018 MSG_RS16265 87781e60eaa419e6095e2cfe93d1a95e 172 SUPERFAMILY SSF54427 64 168 6.27E-7 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS13330 95ee8735e1192f9f2d6364c146fff8f2 164 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 140 3.8E-6 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS13330 95ee8735e1192f9f2d6364c146fff8f2 164 SUPERFAMILY SSF55961 1 141 1.12E-13 T 29-03-2018 MSG_RS13330 95ee8735e1192f9f2d6364c146fff8f2 164 Gene3D G3DSA:3.30.530.20 2 158 8.9E-16 T 29-03-2018 IPR023393 START-like domain MSG_RS08250 17b048a38051bea31d9b1f37cdf68009 57 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 17 38 0.0028 T 29-03-2018 IPR006530 YD repeat MSG_RS14540 83031974668a0fb068609b17c4e3c0fa 133 Gene3D G3DSA:3.30.50.10 20 81 0.0016 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MSG_RS15705 9d0ee489940e8ce8b11cda75721d6bc8 140 Pfam PF11253 Protein of unknown function (DUF3052) 11 134 4.7E-56 T 29-03-2018 IPR021412 Protein of unknown function DUF3052 MSG_RS03985 8e6eaca1056281e0ab723daec3ce951c 721 Pfam PF13515 Fusaric acid resistance protein-like 389 515 3.4E-17 T 29-03-2018 MSG_RS03050 2bf5652e3d1094a3ea37fb58a97b7377 141 Pfam PF10825 Protein of unknown function (DUF2752) 44 91 5.7E-18 T 29-03-2018 IPR021215 Protein of unknown function DUF2752 MSG_RS21710 9d62dbe144c057ba0a61395b3d0fa675 140 SUPERFAMILY SSF52833 45 139 3.15E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS21710 9d62dbe144c057ba0a61395b3d0fa675 140 Pfam PF00085 Thioredoxin 52 131 7.5E-12 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MSG_RS21710 9d62dbe144c057ba0a61395b3d0fa675 140 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MSG_RS21710 9d62dbe144c057ba0a61395b3d0fa675 140 Gene3D G3DSA:3.40.30.10 28 65 0.0039 T 29-03-2018 MSG_RS21710 9d62dbe144c057ba0a61395b3d0fa675 140 Gene3D G3DSA:3.40.30.10 66 138 5.5E-17 T 29-03-2018 MSG_RS23235 572874f64b53248b3e80cb70e660d119 136 SUPERFAMILY SSF55874 26 128 1.78E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23235 572874f64b53248b3e80cb70e660d119 136 SMART SM00387 34 134 4.2E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23235 572874f64b53248b3e80cb70e660d119 136 Pfam PF13581 Histidine kinase-like ATPase domain 14 129 4.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS23235 572874f64b53248b3e80cb70e660d119 136 Gene3D G3DSA:3.30.565.10 6 135 9.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MSG_RS22755 8e615b52fab4a0d2f08c31933152e430 266 Gene3D G3DSA:2.60.40.10 107 223 0.0011 T 29-03-2018 IPR013783 Immunoglobulin-like fold MSG_RS23390 973d797b31c53919373bba0776b4680b 375 Pfam PF13810 Domain of unknown function (DUF4185) 53 368 7.7E-55 T 29-03-2018 IPR025442 Domain of unknown function DUF4185 MSG_RS05855 ac38b060e6d166d07cc3a1494e12760d 362 Gene3D G3DSA:3.40.50.10490 23 178 1.5E-5 T 29-03-2018 MSG_RS05855 ac38b060e6d166d07cc3a1494e12760d 362 SUPERFAMILY SSF53697 65 362 2.05E-56 T 29-03-2018 MSG_RS05855 ac38b060e6d166d07cc3a1494e12760d 362 Gene3D G3DSA:3.40.50.10490 197 362 2.0E-31 T 29-03-2018 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 Pfam PF13459 4Fe-4S single cluster domain 3 59 1.3E-14 T 29-03-2018 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 SUPERFAMILY SSF54862 2 61 6.58E-11 T 29-03-2018 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 6.4E-5 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MSG_RS22300 06d98472d593a226f64abe6e04f7cc5b 63 Gene3D G3DSA:3.30.70.20 1 63 2.6E-7 T 29-03-2018 MSG_RS11845 b6c187a6cbb3d69558e1c38b8da79adc 367 Pfam PF01924 Hydrogenase formation hypA family 13 359 5.1E-147 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MSG_RS11845 b6c187a6cbb3d69558e1c38b8da79adc 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 362 4.9E-140 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MSG_RS11845 b6c187a6cbb3d69558e1c38b8da79adc 367 PIRSF PIRSF005622 1 364 1.3E-151 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MSG_RS02130 1227ef1c1f4793ef78f2dd6fcbfaa0f0 482 Pfam PF06762 Lipase maturation factor 121 274 3.0E-59 T 29-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 MSG_RS02130 1227ef1c1f4793ef78f2dd6fcbfaa0f0 482 Pfam PF06762 Lipase maturation factor 290 471 5.9E-65 T 29-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 MSG_RS11610 4dd3d5b495f6590774cdc043fd4016e2 474 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 8 94 8.9E-20 T 29-03-2018 IPR024962 YukD-like MSG_RS11610 4dd3d5b495f6590774cdc043fd4016e2 474 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 473 4.2E-102 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS11610 4dd3d5b495f6590774cdc043fd4016e2 474 PIRSF PIRSF017804 1 474 1.4E-91 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS05435 cf1c17b7e29c33ab38fd2788df4b39c2 334 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 49 243 2.4E-19 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MSG_RS05435 cf1c17b7e29c33ab38fd2788df4b39c2 334 Gene3D G3DSA:2.120.10.30 25 333 4.5E-36 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS05435 cf1c17b7e29c33ab38fd2788df4b39c2 334 SUPERFAMILY SSF63829 277 332 1.8E-43 T 29-03-2018 MSG_RS05435 cf1c17b7e29c33ab38fd2788df4b39c2 334 SUPERFAMILY SSF63829 8 243 1.8E-43 T 29-03-2018 MSG_RS06010 5a81710b6ed014cf5ec0cd582835dd4e 244 Pfam PF01988 VIT family 29 237 3.2E-55 T 29-03-2018 IPR008217 Ccc1 family MSG_RS13730 4fcb9bf46b7c53481db02324da9205f3 202 Pfam PF08310 LGFP repeat 86 136 2.6E-5 T 29-03-2018 IPR013207 LGFP MSG_RS23430 d15bd4da34d74556953789eec2e945ee 235 SUPERFAMILY SSF52317 19 213 1.74E-20 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS23430 d15bd4da34d74556953789eec2e945ee 235 Gene3D G3DSA:3.40.50.880 5 214 6.2E-16 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MSG_RS23430 d15bd4da34d74556953789eec2e945ee 235 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 201 8.6E-36 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MSG_RS09015 5a7589f2cf1876d2646a1643b1a6e3e5 335 Pfam PF03631 Virulence factor BrkB 27 284 1.8E-40 T 29-03-2018 IPR017039 Virulence factor BrkB MSG_RS09015 5a7589f2cf1876d2646a1643b1a6e3e5 335 PIRSF PIRSF035875 2 304 3.0E-53 T 29-03-2018 IPR017039 Virulence factor BrkB MSG_RS20800 26d8c2e152b890dcb5d80f26d848946a 256 SUPERFAMILY SSF53955 39 116 6.28E-32 T 29-03-2018 IPR023346 Lysozyme-like domain MSG_RS20800 26d8c2e152b890dcb5d80f26d848946a 256 Gene3D G3DSA:1.10.530.10 13 119 3.6E-31 T 29-03-2018 MSG_RS20800 26d8c2e152b890dcb5d80f26d848946a 256 Pfam PF06737 Transglycosylase-like domain 38 114 3.9E-35 T 29-03-2018 IPR010618 Transglycosylase-like MSG_RS07145 531208dffeaed67b706f257a8d77fb60 259 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 138 225 1.3E-10 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MSG_RS07145 531208dffeaed67b706f257a8d77fb60 259 Gene3D G3DSA:2.30.110.10 2 127 2.9E-8 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS07145 531208dffeaed67b706f257a8d77fb60 259 SUPERFAMILY SSF50475 8 99 8.16E-5 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS07145 531208dffeaed67b706f257a8d77fb60 259 SUPERFAMILY SSF50475 136 226 1.06E-7 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS07145 531208dffeaed67b706f257a8d77fb60 259 Gene3D G3DSA:2.30.110.10 128 234 3.9E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS23095 a0ec4502a6d8334fc591bc95ed68d5ad 219 SUPERFAMILY SSF50494 27 189 1.98E-24 T 29-03-2018 IPR009003 Peptidase S1, PA clan MSG_RS23095 a0ec4502a6d8334fc591bc95ed68d5ad 219 Gene3D G3DSA:2.40.10.10 22 108 3.0E-15 T 29-03-2018 MSG_RS12710 7c6aaa1362aae667eddbcdc5d37b09f9 405 SUPERFAMILY SSF140459 5 173 2.07E-65 T 29-03-2018 MSG_RS12710 7c6aaa1362aae667eddbcdc5d37b09f9 405 Gene3D G3DSA:1.10.287.1060 24 105 1.8E-7 T 29-03-2018 MSG_RS12710 7c6aaa1362aae667eddbcdc5d37b09f9 405 Pfam PF00823 PPE family 7 164 3.2E-65 T 29-03-2018 IPR000030 PPE family MSG_RS12710 7c6aaa1362aae667eddbcdc5d37b09f9 405 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 319 401 4.0E-16 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS23100 d93c31de968e77b6e9c30442a042147d 181 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 32 145 2.6E-32 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MSG_RS20730 089b68018cc4775f76df74d47c39f382 264 Pfam PF11268 Protein of unknown function (DUF3071) 1 171 6.8E-53 T 29-03-2018 IPR021421 Protein of unknown function DUF3071 MSG_RS10705 cf0174a72f1230200a3dbe506cdeed05 118 Pfam PF13564 DoxX-like family 13 109 2.7E-11 T 29-03-2018 IPR032808 DoxX family MSG_RS10745 222be16b036708f916164af66eb1d656 425 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 91 1.5E-8 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MSG_RS10745 222be16b036708f916164af66eb1d656 425 Gene3D G3DSA:3.40.50.2000 257 408 9.1E-26 T 29-03-2018 MSG_RS10745 222be16b036708f916164af66eb1d656 425 SUPERFAMILY SSF53756 1 416 1.43E-91 T 29-03-2018 MSG_RS10745 222be16b036708f916164af66eb1d656 425 Gene3D G3DSA:3.40.50.2000 1 256 2.1E-37 T 29-03-2018 MSG_RS19770 fd894424e15ef6798b1aaf334d6291bc 98 SUPERFAMILY SSF140453 4 97 4.97E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS19770 fd894424e15ef6798b1aaf334d6291bc 98 Gene3D G3DSA:1.10.287.1060 1 98 4.6E-14 T 29-03-2018 MSG_RS19770 fd894424e15ef6798b1aaf334d6291bc 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 1.3E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS19770 fd894424e15ef6798b1aaf334d6291bc 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.6E-19 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 6.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 SUPERFAMILY SSF46689 12 94 6.48E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 Gene3D G3DSA:1.10.10.60 10 51 2.9E-13 T 29-03-2018 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 3.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 Gene3D G3DSA:1.10.357.10 72 199 1.1E-11 T 29-03-2018 MSG_RS14305 b052db499ec1aef37f157dc807a46994 217 Gene3D G3DSA:1.10.260.40 52 71 1.2E-5 T 29-03-2018 MSG_RS03750 8741d4e2122a00147d70802aade4416b 567 Gene3D G3DSA:3.30.420.40 72 264 4.8E-5 T 29-03-2018 MSG_RS03750 8741d4e2122a00147d70802aade4416b 567 SUPERFAMILY SSF53067 149 211 1.81E-5 T 29-03-2018 MSG_RS07155 57f6128319517086de322e351e7af0a5 147 Pfam PF05423 Mycobacterium membrane protein 12 147 1.8E-31 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS02385 67888f903d99173acb9c8643393b26af 97 SUPERFAMILY SSF140453 4 93 8.76E-10 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS02385 67888f903d99173acb9c8643393b26af 97 Gene3D G3DSA:1.10.287.1060 1 97 6.7E-12 T 29-03-2018 MSG_RS02385 67888f903d99173acb9c8643393b26af 97 Pfam PF06013 Proteins of 100 residues with WXG 10 87 1.8E-7 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS02400 dfd16fd1fbdf98c84013701779228bd7 470 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 6 469 4.6E-108 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS02400 dfd16fd1fbdf98c84013701779228bd7 470 PIRSF PIRSF017804 1 470 2.7E-93 T 29-03-2018 IPR006707 Type VII secretion system membrane protein EccD MSG_RS02400 dfd16fd1fbdf98c84013701779228bd7 470 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 88 1.1E-21 T 29-03-2018 IPR024962 YukD-like MSG_RS17310 dceb080b3d8e7304b9b5b446869a6f46 138 Pfam PF13279 Thioesterase-like superfamily 11 111 2.2E-8 T 29-03-2018 MSG_RS17310 dceb080b3d8e7304b9b5b446869a6f46 138 Gene3D G3DSA:3.10.129.10 2 138 3.0E-25 T 29-03-2018 MSG_RS17310 dceb080b3d8e7304b9b5b446869a6f46 138 SUPERFAMILY SSF54637 5 136 5.6E-23 T 29-03-2018 IPR029069 HotDog domain MSG_RS17260 1aa7ba72abc21ea3baac54854323b91b 207 Gene3D G3DSA:3.40.30.10 63 167 4.3E-12 T 29-03-2018 MSG_RS17260 1aa7ba72abc21ea3baac54854323b91b 207 Pfam PF01323 DSBA-like thioredoxin domain 12 165 3.1E-9 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 MSG_RS17260 1aa7ba72abc21ea3baac54854323b91b 207 SUPERFAMILY SSF52833 10 167 2.46E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold MSG_RS17260 1aa7ba72abc21ea3baac54854323b91b 207 Gene3D G3DSA:3.40.30.10 8 62 5.4E-10 T 29-03-2018 MSG_RS02955 fd29c50cbc8cd48e26fe5dbf9c14f253 115 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 114 5.8E-39 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 MSG_RS02955 fd29c50cbc8cd48e26fe5dbf9c14f253 115 SUPERFAMILY SSF103481 10 113 7.72E-7 T 29-03-2018 MSG_RS02955 fd29c50cbc8cd48e26fe5dbf9c14f253 115 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 113 20.576 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 MSG_RS08640 b48a611defad7d85a815a1dd24a76a88 342 SUPERFAMILY SSF51412 109 291 6.26E-48 T 29-03-2018 MSG_RS08640 b48a611defad7d85a815a1dd24a76a88 342 SUPERFAMILY SSF51412 4 72 6.26E-48 T 29-03-2018 MSG_RS08640 b48a611defad7d85a815a1dd24a76a88 342 Pfam PF03060 Nitronate monooxygenase 8 339 6.7E-95 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MSG_RS08640 b48a611defad7d85a815a1dd24a76a88 342 Gene3D G3DSA:3.20.20.70 6 341 3.7E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MSG_RS20140 de637e32e3d42482d9b2e3c2f72c7ef2 240 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 22 239 1.7E-48 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 MSG_RS20140 de637e32e3d42482d9b2e3c2f72c7ef2 240 Pfam PF09323 Domain of unknown function (DUF1980) 9 102 1.8E-8 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 MSG_RS00950 92e78a6c7891ca132f5b1750b283f0ca 591 Pfam PF01740 STAS domain 447 546 5.7E-11 T 29-03-2018 IPR002645 STAS domain MSG_RS00950 92e78a6c7891ca132f5b1750b283f0ca 591 Pfam PF00916 Sulfate permease family 13 392 9.5E-87 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MSG_RS00950 92e78a6c7891ca132f5b1750b283f0ca 591 SUPERFAMILY SSF52091 446 544 4.71E-13 T 29-03-2018 IPR002645 STAS domain MSG_RS00950 92e78a6c7891ca132f5b1750b283f0ca 591 Gene3D G3DSA:3.30.750.24 433 568 3.5E-16 T 29-03-2018 IPR002645 STAS domain MSG_RS05720 df33483557ba829aa4a29b508256b631 226 Pfam PF04138 GtrA-like protein 27 157 6.2E-23 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 MSG_RS19085 db37ba01de3e8c95701f95788daadf30 94 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 23 94 1.0E-19 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS19085 db37ba01de3e8c95701f95788daadf30 94 PIRSF PIRSF010611 1 94 1.3E-39 T 29-03-2018 IPR016572 Uncharacterised conserved protein UCP010611 MSG_RS05975 f70e073b9ff87db57a8597dc487c9756 427 Pfam PF00487 Fatty acid desaturase 69 339 3.7E-37 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MSG_RS23030 63280a3b19049abb798824961b09d362 268 Pfam PF00482 Type II secretion system (T2SS), protein F 97 219 1.3E-9 T 29-03-2018 IPR018076 Type II secretion system F domain MSG_RS11205 c39373ab7a4a3ca82cb18371136e3dba 364 Pfam PF01699 Sodium/calcium exchanger protein 34 184 1.3E-12 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MSG_RS11205 c39373ab7a4a3ca82cb18371136e3dba 364 Pfam PF01699 Sodium/calcium exchanger protein 221 362 3.2E-13 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MSG_RS15195 e9e669c5e3134cf5aa77aab7d8707e42 514 TIGRFAM TIGR03459 crt_membr: carotene biosynthesis associated membrane protein 37 496 6.6E-191 T 29-03-2018 IPR017822 Carotene biosynthesis-associated membrane protein, type-1 MSG_RS00720 e60d66e603dc4565d69473e4de0c4c2a 355 Gene3D G3DSA:1.20.1630.10 39 325 2.9E-45 T 29-03-2018 MSG_RS00720 e60d66e603dc4565d69473e4de0c4c2a 355 Pfam PF03916 Polysulphide reductase, NrfD 50 226 6.4E-17 T 29-03-2018 IPR005614 NrfD family MSG_RS12755 eb1baf425c588c292a66716fb0810896 296 Pfam PF04116 Fatty acid hydroxylase superfamily 90 223 1.1E-25 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MSG_RS22775 507ad397bba34b457547f0e93a52e98e 106 SUPERFAMILY SSF54909 4 99 6.56E-24 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MSG_RS22775 507ad397bba34b457547f0e93a52e98e 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 76 1.1E-18 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MSG_RS22775 507ad397bba34b457547f0e93a52e98e 106 Gene3D G3DSA:3.30.70.100 2 105 5.9E-28 T 29-03-2018 MSG_RS20065 4fd5552404e46b5ee185d519b210d739 264 SUPERFAMILY SSF53335 27 217 5.32E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS20065 4fd5552404e46b5ee185d519b210d739 264 Gene3D G3DSA:3.40.50.150 41 230 6.0E-32 T 29-03-2018 MSG_RS20065 4fd5552404e46b5ee185d519b210d739 264 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 54 192 1.2E-26 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS20065 4fd5552404e46b5ee185d519b210d739 264 Pfam PF05050 Methyltransferase FkbM domain 56 213 4.2E-17 T 29-03-2018 IPR006342 Methyltransferase FkbM MSG_RS01745 021574456734fbb9e2c204903fb5d04b 387 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 305 2.8E-85 T 29-03-2018 IPR005693 Virulence factor Mce protein MSG_RS01745 021574456734fbb9e2c204903fb5d04b 387 Pfam PF02470 MlaD protein 48 121 7.4E-11 T 29-03-2018 IPR003399 Mce/MlaD MSG_RS09145 5b8fb8c58bbeb4e84cf9f74add83896e 211 Pfam PF11452 Protein of unknown function (DUF3000) 24 203 6.4E-72 T 29-03-2018 IPR021555 Protein of unknown function DUF3000 MSG_RS02895 927d467d177f36d46de306ef48023487 236 Pfam PF13827 Domain of unknown function (DUF4189) 142 221 6.3E-9 T 29-03-2018 IPR025240 Domain of unknown function DUF4189 MSG_RS07870 e391f525993a7080caa46fdb388e4b4b 175 Pfam PF12028 Protein of unknown function (DUF3515) 5 168 4.9E-54 T 29-03-2018 IPR021903 Protein of unknown function DUF3515 MSG_RS15030 d6c3f2fd6f745f6c8866c5d076a9df22 318 SUPERFAMILY SSF53335 17 312 8.31E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS15030 d6c3f2fd6f745f6c8866c5d076a9df22 318 Gene3D G3DSA:3.40.50.150 4 296 8.3E-54 T 29-03-2018 MSG_RS15030 d6c3f2fd6f745f6c8866c5d076a9df22 318 Pfam PF04072 Leucine carboxyl methyltransferase 21 212 2.2E-64 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MSG_RS15030 d6c3f2fd6f745f6c8866c5d076a9df22 318 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 293 5.7E-80 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MSG_RS21565 cb7a6daeda4ebf322abeefcdad4bd5b2 508 Gene3D G3DSA:3.90.1300.10 76 508 1.5E-125 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS21565 cb7a6daeda4ebf322abeefcdad4bd5b2 508 SUPERFAMILY SSF75304 36 506 5.89E-115 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS21565 cb7a6daeda4ebf322abeefcdad4bd5b2 508 Pfam PF01425 Amidase 42 491 6.6E-111 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MSG_RS21565 cb7a6daeda4ebf322abeefcdad4bd5b2 508 ProSitePatterns PS00571 Amidases signature. 169 200 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MSG_RS24260 ff1e281930598a02a940fe860102d7f9 520 Pfam PF01593 Flavin containing amine oxidoreductase 216 328 2.9E-7 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MSG_RS24260 ff1e281930598a02a940fe860102d7f9 520 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 68 6.5E-9 T 29-03-2018 MSG_RS24260 ff1e281930598a02a940fe860102d7f9 520 Gene3D G3DSA:3.50.50.60 2 517 3.3E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24260 ff1e281930598a02a940fe860102d7f9 520 SUPERFAMILY SSF51905 368 397 1.83E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS24260 ff1e281930598a02a940fe860102d7f9 520 SUPERFAMILY SSF51905 1 332 1.83E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS11600 18cf3e07d775ed70b13cec4a12565736 526 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 33 500 1.1E-161 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS11600 18cf3e07d775ed70b13cec4a12565736 526 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 31 513 1.2E-172 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS06650 cb0a88928eeae4cefb1295d4f675e76c 371 SUPERFAMILY SSF159245 22 267 1.83E-7 T 29-03-2018 MSG_RS07050 765195e26964ea385df71bf92dfcd53a 487 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 27 456 1.0E-104 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 MSG_RS07050 765195e26964ea385df71bf92dfcd53a 487 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 473 43.651 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 MSG_RS02590 fdfc6c6e7e725b46a5a81c90aa557a58 369 SUPERFAMILY SSF47240 91 319 5.58E-70 T 29-03-2018 IPR009078 Ferritin-like superfamily MSG_RS02590 fdfc6c6e7e725b46a5a81c90aa557a58 369 Gene3D G3DSA:1.10.620.20 18 303 3.2E-58 T 29-03-2018 MSG_RS02590 fdfc6c6e7e725b46a5a81c90aa557a58 369 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 36 306 2.3E-12 T 29-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF MSG_RS06240 4a641ef1e7cb3f46579b272a1e177a78 86 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 1.5E-29 T 29-03-2018 IPR021456 Protein of unknown function DUF3107 MSG_RS06875 23ae9ac12c3a85988630ff41af6128ec 154 PRINTS PR01217 Proline rich extensin signature 130 154 1.4E-10 T 29-03-2018 MSG_RS06875 23ae9ac12c3a85988630ff41af6128ec 154 PRINTS PR01217 Proline rich extensin signature 84 100 1.4E-10 T 29-03-2018 MSG_RS06875 23ae9ac12c3a85988630ff41af6128ec 154 PRINTS PR01217 Proline rich extensin signature 53 74 1.4E-10 T 29-03-2018 MSG_RS06875 23ae9ac12c3a85988630ff41af6128ec 154 PRINTS PR01217 Proline rich extensin signature 106 123 1.4E-10 T 29-03-2018 MSG_RS00155 5e927873e878d9b05df61b8341a0b02c 295 Gene3D G3DSA:1.10.10.10 134 274 2.6E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MSG_RS08420 ab4ec85da93c00a32307bfbc736ce6ee 198 Pfam PF08044 Domain of unknown function (DUF1707) 14 66 1.4E-17 T 29-03-2018 IPR012551 Protein of unknown function DUF1707 MSG_RS24115 07232a40978978ac8c5a20f07468fc0a 1109 Pfam PF14896 EmbC C-terminal domain 712 1106 1.7E-148 T 29-03-2018 IPR032731 Arabinosyltransferase, C-terminal MSG_RS24115 07232a40978978ac8c5a20f07468fc0a 1109 Gene3D G3DSA:2.60.120.610 33 204 5.9E-52 T 29-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 MSG_RS24115 07232a40978978ac8c5a20f07468fc0a 1109 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 12 677 1.3E-258 T 29-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 MSG_RS06125 f4a2ccc5321340a3d1665d20c6242dce 591 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 579 3.9E-263 T 29-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane MSG_RS20185 fe8815cce7b1ac8917f223f903c4da18 203 Gene3D G3DSA:3.40.630.30 4 189 8.1E-25 T 29-03-2018 MSG_RS20185 fe8815cce7b1ac8917f223f903c4da18 203 SUPERFAMILY SSF55729 13 181 1.62E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MSG_RS20185 fe8815cce7b1ac8917f223f903c4da18 203 Pfam PF13302 Acetyltransferase (GNAT) domain 14 158 1.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MSG_RS10035 b7bf95db6c4593d23f7f64b71f0db314 211 SUPERFAMILY SSF56281 12 203 9.07E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10035 b7bf95db6c4593d23f7f64b71f0db314 211 Pfam PF00753 Metallo-beta-lactamase superfamily 28 190 4.8E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10035 b7bf95db6c4593d23f7f64b71f0db314 211 SMART SM00849 27 190 1.7E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS10035 b7bf95db6c4593d23f7f64b71f0db314 211 Gene3D G3DSA:3.60.15.10 19 209 2.8E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS07395 6120cfeba8b0be723957a6a9a7a210fc 148 SUPERFAMILY SSF55961 1 138 7.4E-33 T 29-03-2018 MSG_RS07395 6120cfeba8b0be723957a6a9a7a210fc 148 Gene3D G3DSA:3.30.530.20 1 140 4.4E-25 T 29-03-2018 IPR023393 START-like domain MSG_RS07395 6120cfeba8b0be723957a6a9a7a210fc 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 138 2.0E-18 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS03120 86ff81221ca2eb5ca84fbcfc207b91ef 254 Gene3D G3DSA:3.40.630.30 200 254 3.7E-5 T 29-03-2018 MSG_RS13620 50e2db6a570cfdafbb03a5c9a947518c 182 SUPERFAMILY SSF51182 44 169 2.26E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain MSG_RS13620 50e2db6a570cfdafbb03a5c9a947518c 182 Gene3D G3DSA:2.60.120.10 37 182 4.0E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MSG_RS12765 06e1b10d5153f2e491f94260dd3bb328 148 Pfam PF04075 F420H(2)-dependent quinone reductase 26 111 1.4E-8 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS12765 06e1b10d5153f2e491f94260dd3bb328 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 33 113 8.5E-14 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS12765 06e1b10d5153f2e491f94260dd3bb328 148 Gene3D G3DSA:2.30.110.10 6 147 1.0E-17 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS13145 63f72db89c496556148fc2d48379958a 63 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 3.1E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MSG_RS21495 7be4154cb97ea953705547b6182458b2 294 SUPERFAMILY SSF52518 3 281 2.74E-37 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MSG_RS21495 7be4154cb97ea953705547b6182458b2 294 Pfam PF00676 Dehydrogenase E1 component 36 243 1.1E-21 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MSG_RS21495 7be4154cb97ea953705547b6182458b2 294 Gene3D G3DSA:3.40.50.970 1 287 1.2E-25 T 29-03-2018 MSG_RS15790 3604527991bc66398f446c815a17e4b0 170 Pfam PF11343 Protein of unknown function (DUF3145) 14 167 6.5E-71 T 29-03-2018 IPR021491 Protein of unknown function DUF3145 MSG_RS22205 71759436e7c5603bd595e689bb80f5b8 523 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 383 468 6.3E-11 T 29-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MSG_RS22205 71759436e7c5603bd595e689bb80f5b8 523 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 280 6.9E-28 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS22205 71759436e7c5603bd595e689bb80f5b8 523 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 281 3.1E-41 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MSG_RS05090 dbf170b20ecbdda933ff8c4b3901ab7f 102 Pfam PF02467 Transcription factor WhiB 17 85 1.5E-24 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS05090 dbf170b20ecbdda933ff8c4b3901ab7f 102 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.94 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS12735 46c1e3459059c4332fff81e828de42b4 107 Pfam PF05305 Protein of unknown function (DUF732) 6 104 3.7E-24 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS03645 9691af272fc53abe3dd8a72188f7682b 291 SUPERFAMILY SSF53474 63 290 1.79E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03645 9691af272fc53abe3dd8a72188f7682b 291 Gene3D G3DSA:3.40.50.1820 44 291 1.7E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03645 9691af272fc53abe3dd8a72188f7682b 291 Pfam PF00756 Putative esterase 76 288 4.6E-7 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MSG_RS12505 015b91d77f7fdfb14af9ac5d398cf87f 181 Gene3D G3DSA:3.40.50.150 2 140 2.1E-17 T 29-03-2018 MSG_RS12505 015b91d77f7fdfb14af9ac5d398cf87f 181 Pfam PF13649 Methyltransferase domain 44 115 3.2E-10 T 29-03-2018 MSG_RS12505 015b91d77f7fdfb14af9ac5d398cf87f 181 SUPERFAMILY SSF53335 5 162 3.65E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 Gene3D G3DSA:3.40.50.1820 4 273 6.0E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 SUPERFAMILY SSF53474 5 273 2.63E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 217 233 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 30 48 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 250 272 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 50 65 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00412 Epoxide hydrolase signature 108 121 2.1E-17 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS13490 75f424993fbc6ea1f000505a1f9d5fd1 273 Pfam PF00561 alpha/beta hydrolase fold 24 261 3.1E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MSG_RS18160 6fcc47b3a1a0801bc192f1060d3d45ce 464 SUPERFAMILY SSF52777 35 230 5.0E-17 T 29-03-2018 MSG_RS18160 6fcc47b3a1a0801bc192f1060d3d45ce 464 Gene3D G3DSA:3.30.559.10 16 219 7.7E-13 T 29-03-2018 MSG_RS18160 6fcc47b3a1a0801bc192f1060d3d45ce 464 SUPERFAMILY SSF52777 225 457 8.56E-15 T 29-03-2018 MSG_RS18160 6fcc47b3a1a0801bc192f1060d3d45ce 464 Pfam PF00668 Condensation domain 68 363 5.5E-18 T 29-03-2018 IPR001242 Condensation domain MSG_RS01715 612c3b79d69457395d4454e381f818c6 259 Pfam PF02405 Permease MlaE 40 250 2.2E-56 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS18645 d5eef593858b555a2975f60996d44ed2 333 Gene3D G3DSA:3.40.50.720 12 324 6.3E-16 T 29-03-2018 MSG_RS18645 d5eef593858b555a2975f60996d44ed2 333 SUPERFAMILY SSF51735 20 290 1.62E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS18645 d5eef593858b555a2975f60996d44ed2 333 Pfam PF05368 NmrA-like family 23 249 1.8E-18 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 MSG_RS07575 6774d9c52ff1f5eaaca1498d4555d97c 241 Pfam PF01209 ubiE/COQ5 methyltransferase family 43 223 1.5E-20 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MSG_RS07575 6774d9c52ff1f5eaaca1498d4555d97c 241 Gene3D G3DSA:3.40.50.150 10 235 5.8E-35 T 29-03-2018 MSG_RS07575 6774d9c52ff1f5eaaca1498d4555d97c 241 SUPERFAMILY SSF53335 13 230 4.65E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS24475 00d831c7c935b3862ab9ce0566f7fba9 201 Gene3D G3DSA:3.30.1310.10 56 161 4.8E-4 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MSG_RS00255 586b4ca9c58c53020fcdc82583e80379 202 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 18 199 25.678 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 MSG_RS00255 586b4ca9c58c53020fcdc82583e80379 202 Gene3D G3DSA:3.40.1740.10 116 190 4.9E-11 T 29-03-2018 MSG_RS00255 586b4ca9c58c53020fcdc82583e80379 202 Gene3D G3DSA:3.40.1740.10 6 101 4.5E-16 T 29-03-2018 MSG_RS00255 586b4ca9c58c53020fcdc82583e80379 202 SUPERFAMILY SSF143456 17 196 8.76E-45 T 29-03-2018 MSG_RS00255 586b4ca9c58c53020fcdc82583e80379 202 Pfam PF02622 Uncharacterized ACR, COG1678 31 185 5.7E-35 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 MSG_RS20875 0b4e43d84dd0cdd24f54541b7ea913cc 110 SUPERFAMILY SSF55298 1 105 3.46E-23 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS20875 0b4e43d84dd0cdd24f54541b7ea913cc 110 Pfam PF01042 Endoribonuclease L-PSP 1 103 2.9E-19 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MSG_RS20875 0b4e43d84dd0cdd24f54541b7ea913cc 110 Gene3D G3DSA:3.30.1330.40 1 106 1.6E-21 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MSG_RS13700 eafbed17db5bf7dacc4a4b6c89ef8f87 393 Gene3D G3DSA:3.40.710.10 64 391 3.4E-38 T 29-03-2018 MSG_RS13700 eafbed17db5bf7dacc4a4b6c89ef8f87 393 SUPERFAMILY SSF56601 8 381 7.1E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS13700 eafbed17db5bf7dacc4a4b6c89ef8f87 393 Pfam PF00144 Beta-lactamase 74 384 8.0E-36 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS08875 569af74f14e01d2f51d2753e2b68da8c 68 Pfam PF11248 Protein of unknown function (DUF3046) 5 65 1.6E-28 T 29-03-2018 IPR021408 Protein of unknown function DUF3046 MSG_RS01930 91af76fcc510a3500f4e38865705c595 244 Gene3D G3DSA:3.40.50.1010 28 208 3.1E-25 T 29-03-2018 IPR029060 PIN domain-like MSG_RS00195 23897956db9e69da7658295853dd1737 120 Pfam PF10774 Domain of unknown function (DUF4226) 4 115 5.8E-37 T 29-03-2018 IPR019710 Protein of unknown function DUF4226 MSG_RS14870 bcd51c1529881cc9c68455ef74ed79c2 255 Pfam PF12151 Mannan-binding protein 22 57 7.0E-15 T 29-03-2018 IPR021992 Mannan-binding protein MSG_RS14870 bcd51c1529881cc9c68455ef74ed79c2 255 Pfam PF11738 Protein of unknown function (DUF3298) 148 247 7.2E-13 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 MSG_RS17675 561e22f63bd686c5210546ab4b974ecc 141 Gene3D G3DSA:3.10.450.50 8 138 2.0E-8 T 29-03-2018 MSG_RS17675 561e22f63bd686c5210546ab4b974ecc 141 Pfam PF13577 SnoaL-like domain 18 126 3.9E-7 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS17675 561e22f63bd686c5210546ab4b974ecc 141 SUPERFAMILY SSF54427 1 138 4.55E-15 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS00930 f75d39213c1437474d219b550b4d0d94 602 SUPERFAMILY SSF51905 390 483 1.43E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00930 f75d39213c1437474d219b550b4d0d94 602 SUPERFAMILY SSF51905 64 292 1.43E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00930 f75d39213c1437474d219b550b4d0d94 602 Gene3D G3DSA:3.50.50.60 55 227 7.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00930 f75d39213c1437474d219b550b4d0d94 602 Gene3D G3DSA:3.50.50.60 228 596 5.5E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS00930 f75d39213c1437474d219b550b4d0d94 602 Pfam PF00743 Flavin-binding monooxygenase-like 65 275 2.3E-10 T 29-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MSG_RS21855 9e38891393949f57f803b30757c44df6 230 SUPERFAMILY SSF46689 12 84 7.7E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MSG_RS21855 9e38891393949f57f803b30757c44df6 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MSG_RS21855 9e38891393949f57f803b30757c44df6 230 SUPERFAMILY SSF48498 99 206 1.1E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS21855 9e38891393949f57f803b30757c44df6 230 Gene3D G3DSA:1.10.10.60 13 69 3.0E-15 T 29-03-2018 MSG_RS21855 9e38891393949f57f803b30757c44df6 230 Gene3D G3DSA:1.10.357.10 70 215 1.7E-15 T 29-03-2018 MSG_RS17430 013f2a7db3d90532b6e820cee0a00613 409 Pfam PF04909 Amidohydrolase 99 391 1.6E-25 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MSG_RS17430 013f2a7db3d90532b6e820cee0a00613 409 Gene3D G3DSA:3.20.20.140 3 396 1.5E-61 T 29-03-2018 MSG_RS17430 013f2a7db3d90532b6e820cee0a00613 409 SUPERFAMILY SSF51556 8 37 2.44E-65 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS17430 013f2a7db3d90532b6e820cee0a00613 409 SUPERFAMILY SSF51556 91 392 2.44E-65 T 29-03-2018 IPR032466 Metal-dependent hydrolase MSG_RS08435 b92dba7d5512ab5adbf92746592324c7 184 SUPERFAMILY SSF53474 3 115 5.09E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS08435 b92dba7d5512ab5adbf92746592324c7 184 Gene3D G3DSA:3.40.50.1820 4 180 9.4E-8 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS12600 f2636fe0d72e9b651ad19b21e44da346 592 Pfam PF14362 Domain of unknown function (DUF4407) 33 312 3.7E-51 T 29-03-2018 IPR025519 Protein of unknown function DUF4407 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 SUPERFAMILY SSF141130 20 173 2.09E-73 T 29-03-2018 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 SUPERFAMILY SSF141130 222 393 2.09E-73 T 29-03-2018 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 Gene3D G3DSA:2.60.120.580 8 157 1.8E-30 T 29-03-2018 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 Gene3D G3DSA:2.60.120.580 158 290 2.6E-32 T 29-03-2018 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 Pfam PF03069 Acetamidase/Formamidase family 9 394 2.4E-165 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 MSG_RS06370 573ad1b2b60414e7bd5c0ad1f5c5c7e7 417 Gene3D G3DSA:3.10.28.20 304 393 3.4E-15 T 29-03-2018 MSG_RS04340 696bb3494d3f59b8b3f74737272d4d66 103 TIGRFAM TIGR03967 mycofact_MftB: putative mycofactocin binding protein MftB 17 96 1.8E-29 T 29-03-2018 IPR023850 Putative mycofactocin binding protein MftB MSG_RS22795 817413983a29ccf42638fd1b47f2d8a7 74 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 20 74 1.1E-15 T 29-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative MSG_RS05865 b36958a5ad6ef4f431bf100f727caa38 465 SUPERFAMILY SSF51905 2 194 1.49E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05865 b36958a5ad6ef4f431bf100f727caa38 465 SUPERFAMILY SSF51905 300 400 1.49E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS05865 b36958a5ad6ef4f431bf100f727caa38 465 Gene3D G3DSA:3.50.50.60 1 463 2.3E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MSG_RS04435 3d217ab017cf7b6a2bf7dac5c552f742 287 Gene3D G3DSA:3.30.420.10 54 271 5.2E-11 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MSG_RS04435 3d217ab017cf7b6a2bf7dac5c552f742 287 Gene3D G3DSA:1.10.10.60 6 46 3.6E-5 T 29-03-2018 MSG_RS20890 0968be0076b8b08db3c670ff1e6b59d0 271 SUPERFAMILY SSF161098 73 258 1.7E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS20890 0968be0076b8b08db3c670ff1e6b59d0 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 266 7.6E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MSG_RS20890 0968be0076b8b08db3c670ff1e6b59d0 271 Gene3D G3DSA:1.10.3720.10 27 271 4.9E-26 T 29-03-2018 MSG_RS10190 d3fac33fa4a5fa27f557626c3c6a3737 401 Pfam PF00144 Beta-lactamase 19 371 9.4E-68 T 29-03-2018 IPR001466 Beta-lactamase-related MSG_RS10190 d3fac33fa4a5fa27f557626c3c6a3737 401 SUPERFAMILY SSF56601 7 370 1.26E-82 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS10190 d3fac33fa4a5fa27f557626c3c6a3737 401 Gene3D G3DSA:3.40.710.10 6 390 9.1E-80 T 29-03-2018 MSG_RS03690 92a25adecef7faef3d04b353aa8102b7 263 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 241 1.1E-38 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MSG_RS17165 246ef982fa2f4ed165406e06e525e1e4 130 Pfam PF14017 Protein of unknown function (DUF4233) 21 122 6.2E-27 T 29-03-2018 IPR025327 Protein of unknown function DUF4233 MSG_RS12455 d6b1bda684d572e99905cb64bfcb14a3 206 Gene3D G3DSA:3.40.190.10 4 202 3.1E-4 T 29-03-2018 MSG_RS06720 ad3aed00b6ecb25b31aaae0a44e12a99 263 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 36 181 2.3E-28 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MSG_RS07750 3428f3824892feddb4f5edc12db6e397 280 Pfam PF07681 DoxX 116 196 1.4E-15 T 29-03-2018 IPR032808 DoxX family MSG_RS03330 32f1f4e6a49752e4cbe5800423978f2d 79 Pfam PF16936 Putative holin 1 78 3.2E-34 T 29-03-2018 IPR031614 Putative holin MSG_RS04430 cc59038322cd796fc00dc7c745490e45 124 Gene3D G3DSA:1.10.10.60 83 119 1.9E-5 T 29-03-2018 MSG_RS04430 cc59038322cd796fc00dc7c745490e45 124 Gene3D G3DSA:3.30.2390.10 2 82 1.1E-5 T 29-03-2018 IPR035069 TTHA1013/TTHA0281-like MSG_RS17535 b73c19d2ebbd89504d5c1121c4df7d09 598 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 575 4.2E-264 T 29-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane MSG_RS00565 0cfb25f824504232570e4a267cded0bd 138 SUPERFAMILY SSF54427 3 108 1.09E-23 T 29-03-2018 IPR032710 NTF2-like domain MSG_RS00565 0cfb25f824504232570e4a267cded0bd 138 Gene3D G3DSA:3.10.450.50 2 136 7.0E-22 T 29-03-2018 MSG_RS00565 0cfb25f824504232570e4a267cded0bd 138 Pfam PF12680 SnoaL-like domain 5 99 1.7E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MSG_RS01250 45abfa841c8ed6d7606309723e4a303e 226 Pfam PF06912 Protein of unknown function (DUF1275) 13 213 4.6E-27 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 MSG_RS22090 625bb26ecd598a43a41c3d4adf058d90 400 SUPERFAMILY SSF51197 8 296 1.65E-42 T 29-03-2018 MSG_RS22090 625bb26ecd598a43a41c3d4adf058d90 400 Pfam PF08007 Cupin superfamily protein 16 238 1.5E-39 T 29-03-2018 IPR003347 JmjC domain MSG_RS22090 625bb26ecd598a43a41c3d4adf058d90 400 Gene3D G3DSA:2.60.120.650 3 229 2.4E-21 T 29-03-2018 MSG_RS19625 21b9bd7d7368e8064497c8a3e22463ee 144 Pfam PF14155 Domain of unknown function (DUF4307) 23 133 9.5E-35 T 29-03-2018 IPR025443 Protein of unknown function DUF4307 MSG_RS13385 973f7e67e48b4884031ed0eac8b7c843 240 Pfam PF00753 Metallo-beta-lactamase superfamily 19 215 8.1E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13385 973f7e67e48b4884031ed0eac8b7c843 240 Gene3D G3DSA:3.60.15.10 6 238 1.5E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13385 973f7e67e48b4884031ed0eac8b7c843 240 SMART SM00849 21 215 6.1E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS13385 973f7e67e48b4884031ed0eac8b7c843 240 SUPERFAMILY SSF56281 5 233 2.98E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase MSG_RS00090 76b8f39b126a46757156149b4b53191e 247 Pfam PF05949 Bacterial protein of unknown function (DUF881) 89 239 1.5E-36 T 29-03-2018 IPR010273 Protein of unknown function DUF881 MSG_RS13765 54ebebedfc5774c4b72bddb057ee0cdd 165 Pfam PF04075 F420H(2)-dependent quinone reductase 63 115 1.6E-4 T 29-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 MSG_RS13765 54ebebedfc5774c4b72bddb057ee0cdd 165 Gene3D G3DSA:2.30.110.10 35 157 1.1E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MSG_RS08015 6df438a7639951d9c8f3f9d9e8e103e2 416 Gene3D G3DSA:3.40.50.720 2 135 8.4E-22 T 29-03-2018 MSG_RS08015 6df438a7639951d9c8f3f9d9e8e103e2 416 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 8 135 3.9E-13 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MSG_RS08015 6df438a7639951d9c8f3f9d9e8e103e2 416 SUPERFAMILY SSF51735 8 164 5.24E-16 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS20145 4b0a25902b8c6c600cbec95867b6fc19 320 Pfam PF03773 Predicted permease 29 307 1.2E-43 T 29-03-2018 IPR005524 Predicted permease DUF318 MSG_RS22880 b68f1d94f2d653532c7a2229999c33c6 395 Gene3D G3DSA:3.20.20.30 13 391 1.7E-68 T 29-03-2018 MSG_RS22880 b68f1d94f2d653532c7a2229999c33c6 395 SUPERFAMILY SSF51679 5 351 2.36E-75 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS22880 b68f1d94f2d653532c7a2229999c33c6 395 Pfam PF00296 Luciferase-like monooxygenase 5 317 6.9E-45 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MSG_RS01350 15c7578e0dedf83984a39e4213ce086b 112 Gene3D G3DSA:1.10.1470.10 9 110 7.5E-4 T 29-03-2018 IPR008462 CsbD-like domain MSG_RS11120 8bc9275af2a4117c53127185d542bf38 446 PIRSF PIRSF029171 27 407 2.0E-34 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 MSG_RS11120 8bc9275af2a4117c53127185d542bf38 446 SUPERFAMILY SSF53474 297 398 1.99E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11120 8bc9275af2a4117c53127185d542bf38 446 SUPERFAMILY SSF53474 141 239 1.99E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11120 8bc9275af2a4117c53127185d542bf38 446 Gene3D G3DSA:3.40.50.1820 64 405 2.3E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS11120 8bc9275af2a4117c53127185d542bf38 446 Pfam PF03583 Secretory lipase 129 406 1.8E-88 T 29-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 MSG_RS07745 41c1566549be9904b57b677c7b5a6bb1 373 Pfam PF07995 Glucose / Sorbosone dehydrogenase 79 224 7.2E-15 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase MSG_RS07745 41c1566549be9904b57b677c7b5a6bb1 373 Gene3D G3DSA:2.120.10.30 66 279 3.1E-15 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MSG_RS07745 41c1566549be9904b57b677c7b5a6bb1 373 SUPERFAMILY SSF50952 54 336 1.57E-14 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MSG_RS24620 eb2e075bdc7c4ca323dc6f008f18c34f 106 SUPERFAMILY SSF140453 6 100 9.81E-9 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24620 eb2e075bdc7c4ca323dc6f008f18c34f 106 Pfam PF06013 Proteins of 100 residues with WXG 6 89 1.3E-9 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like MSG_RS24620 eb2e075bdc7c4ca323dc6f008f18c34f 106 Gene3D G3DSA:1.10.287.1060 1 99 1.5E-8 T 29-03-2018 MSG_RS02490 6136b1bcf539329a0d67da1e0cd52917 250 Pfam PF11259 Protein of unknown function (DUF3060) 187 242 1.2E-22 T 29-03-2018 IPR021417 Protein of unknown function DUF3060 MSG_RS09480 f9c1a21b05a1555b3176669b29e7a769 260 Pfam PF01925 Sulfite exporter TauE/SafE 11 252 1.1E-38 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MSG_RS15710 1a468d4f03a61f18cf1f23442696b006 195 Gene3D G3DSA:1.10.287.1060 73 170 0.0016 T 29-03-2018 MSG_RS11715 35748fea65e3ff087b16e8023a774b46 314 Pfam PF11382 Copper transport outer membrane protein, MctB 1 311 5.8E-92 T 29-03-2018 IPR021522 Copper transporter MctB GO:0006810 MSG_RS08820 05e83efb7623bf5e2d3b02a882530724 104 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 2 98 2.1E-22 T 29-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 MSG_RS08820 05e83efb7623bf5e2d3b02a882530724 104 Gene3D G3DSA:1.10.287.1060 1 99 7.3E-7 T 29-03-2018 MSG_RS07695 39ad73b9afd755eb8a92b0de11a1fc72 134 Pfam PF05423 Mycobacterium membrane protein 2 133 1.5E-53 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS05150 6d5d3862cfe6c47afaa9ec3454517d62 268 SUPERFAMILY SSF53335 38 219 3.5E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS05150 6d5d3862cfe6c47afaa9ec3454517d62 268 Gene3D G3DSA:3.40.50.150 3 267 9.4E-34 T 29-03-2018 MSG_RS05150 6d5d3862cfe6c47afaa9ec3454517d62 268 Pfam PF08241 Methyltransferase domain 67 163 7.1E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS23570 03b8b9812f3bd1e524823efb6fd15c22 227 Pfam PF11139 Sap, sulfolipid-1-addressing protein 10 219 2.9E-9 T 29-03-2018 IPR021315 Glycolipid exporter Gap/Sap MSG_RS14920 3265e6bfcc7bacde7a112107da28da66 195 Pfam PF11290 Protein of unknown function (DUF3090) 6 175 3.0E-68 T 29-03-2018 IPR021441 Protein of unknown function DUF3090 MSG_RS14920 3265e6bfcc7bacde7a112107da28da66 195 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 179 4.1E-78 T 29-03-2018 IPR021441 Protein of unknown function DUF3090 MSG_RS19725 1a08cba9c3b20ce99af6eeeae7163e24 260 Pfam PF04248 Domain of unknown function (DUF427) 27 109 1.3E-8 T 29-03-2018 IPR007361 Domain of unknown function DUF427 MSG_RS19725 1a08cba9c3b20ce99af6eeeae7163e24 260 Pfam PF04248 Domain of unknown function (DUF427) 144 241 2.4E-28 T 29-03-2018 IPR007361 Domain of unknown function DUF427 MSG_RS24270 8e1a9387bef572bcc346b381ef88d3af 161 Pfam PF11196 Protein of unknown function (DUF2834) 41 148 2.1E-32 T 29-03-2018 IPR021362 Protein of unknown function DUF2834 MSG_RS16750 e08be068ddb87e181c46cd61bfd1eeff 177 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 65 172 6.0E-46 T 29-03-2018 IPR020235 Low molecular weight antigen MTB12 MSG_RS03870 3e05d09328230676347d1c7fa9b8479d 131 Pfam PF05305 Protein of unknown function (DUF732) 12 121 2.7E-21 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS21030 99e24713a07de11ad2e0c300ae19e784 142 PIRSF PIRSF021591 2 142 3.6E-39 T 29-03-2018 IPR016793 Uncharacterised conserved protein UCP021591 MSG_RS15170 857e9f7dc4b172bf7e0c25faf19fda7c 133 Pfam PF11239 Protein of unknown function (DUF3040) 1 87 4.7E-29 T 29-03-2018 IPR021401 Protein of unknown function DUF3040 MSG_RS02240 b7c27b79547eee3a3fba0e3a41a51217 150 Gene3D G3DSA:1.10.357.10 20 148 6.1E-24 T 29-03-2018 MSG_RS02240 b7c27b79547eee3a3fba0e3a41a51217 150 SUPERFAMILY SSF48498 37 147 1.07E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MSG_RS22320 894ab108925ec459abe516edbbbe5ee3 235 Gene3D G3DSA:3.40.710.10 45 229 3.9E-7 T 29-03-2018 MSG_RS22320 894ab108925ec459abe516edbbbe5ee3 235 SUPERFAMILY SSF56601 47 227 4.44E-7 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MSG_RS22900 d645c0ba162d8c80f99807eae636f51a 245 Pfam PF04402 Protein of unknown function (DUF541) 46 242 3.2E-40 T 29-03-2018 IPR007497 Protein of unknown function DUF541 MSG_RS00340 77e72e1e86dd22c399ea3627518c431b 548 Pfam PF09594 Glycosyltransferase family 87 190 414 4.6E-14 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MSG_RS00340 77e72e1e86dd22c399ea3627518c431b 548 PIRSF PIRSF010361 27 516 4.0E-182 T 29-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane MSG_RS17570 ec4bbbd1a8e0a063ef60af2fe39cd702 149 Gene3D G3DSA:3.30.530.20 1 148 4.0E-21 T 29-03-2018 IPR023393 START-like domain MSG_RS17570 ec4bbbd1a8e0a063ef60af2fe39cd702 149 SUPERFAMILY SSF55961 4 140 9.59E-21 T 29-03-2018 MSG_RS17570 ec4bbbd1a8e0a063ef60af2fe39cd702 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 120 1.7E-17 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase MSG_RS16910 8161ccf6c53caf57243f05a766674d2a 244 Pfam PF14032 PknH-like extracellular domain 41 238 2.6E-30 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS06030 79ac55162e91cddccbd1ff6005bcafc6 265 Pfam PF13560 Helix-turn-helix domain 20 62 1.6E-8 T 29-03-2018 MSG_RS06030 79ac55162e91cddccbd1ff6005bcafc6 265 Gene3D G3DSA:1.10.260.40 17 77 6.2E-7 T 29-03-2018 MSG_RS06390 4bb715c90b2e04e88c8dad9d857a0b92 90 SUPERFAMILY SSF103473 3 86 1.57E-7 T 29-03-2018 IPR020846 Major facilitator superfamily domain MSG_RS06390 4bb715c90b2e04e88c8dad9d857a0b92 90 Gene3D G3DSA:1.20.1250.20 1 87 4.6E-7 T 29-03-2018 MSG_RS03085 35af93502630ffe66df2da7b463fdfce 208 Gene3D G3DSA:3.40.50.1820 3 207 6.8E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS03085 35af93502630ffe66df2da7b463fdfce 208 SUPERFAMILY SSF53474 7 205 3.04E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MSG_RS21135 099b68ccb7e71ba4bb3d08dfe612a0d8 401 Gene3D G3DSA:3.40.50.10540 1 401 2.1E-96 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21135 099b68ccb7e71ba4bb3d08dfe612a0d8 401 SUPERFAMILY SSF89796 1 400 6.93E-95 T 29-03-2018 IPR023606 CoA-transferase family III domain MSG_RS21135 099b68ccb7e71ba4bb3d08dfe612a0d8 401 Pfam PF02515 CoA-transferase family III 4 376 3.8E-81 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 MSG_RS06320 344033294c73381ea5d9354be0c286a5 286 Gene3D G3DSA:3.40.50.720 44 286 6.5E-13 T 29-03-2018 MSG_RS06565 f51719c3c00d8894872f6bbb061b2d14 85 Gene3D G3DSA:1.10.720.10 48 85 9.1E-8 T 29-03-2018 MSG_RS05835 d5a3a375512863de9c02448d7212559f 112 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 112 18.752 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS05835 d5a3a375512863de9c02448d7212559f 112 Pfam PF02467 Transcription factor WhiB 44 107 1.1E-26 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS18280 857f2cf29682f8e90e7bcb520d0a206d 154 Pfam PF03899 ATP synthase I chain 21 114 5.4E-9 T 29-03-2018 IPR005598 ATP synthase protein I MSG_RS24450 c31a3ff690ea36338210a54ac17b1f00 93 Pfam PF02467 Transcription factor WhiB 16 59 2.9E-7 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS23755 a81e77b2a8c9f123b25bb2e2128db7b6 128 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 4 117 2.8E-49 T 29-03-2018 IPR018714 Protein of unknown function DUF2237 MSG_RS05175 b536cf1f09f5cd16d2f431202ddf5b9f 228 Gene3D G3DSA:3.40.50.300 67 172 4.3E-5 T 29-03-2018 MSG_RS18405 8303845d64bae445acd4a9a594654043 215 Pfam PF07077 Protein of unknown function (DUF1345) 38 203 5.8E-53 T 29-03-2018 IPR009781 Protein of unknown function DUF1345 MSG_RS09185 e3de7dc017449d542dbd62fd044d2b41 447 Pfam PF09594 Glycosyltransferase family 87 94 329 8.8E-38 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MSG_RS14735 4c5bb1ea959fc58bc3d19b8b0fa782a4 335 Pfam PF13280 WYL domain 154 329 1.1E-31 T 29-03-2018 IPR026881 WYL domain MSG_RS02770 6405ed1d67db7ac7f6f21fd634118158 296 Gene3D G3DSA:2.70.98.10 1 296 3.7E-42 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MSG_RS02770 6405ed1d67db7ac7f6f21fd634118158 296 Pfam PF01263 Aldose 1-epimerase 33 274 5.4E-19 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MSG_RS02770 6405ed1d67db7ac7f6f21fd634118158 296 SUPERFAMILY SSF74650 3 295 4.58E-38 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MSG_RS20250 cebeb2b3bd9a8e5fa7b935e0a9a9e3fb 570 Gene3D G3DSA:3.10.450.50 319 518 0.0013 T 29-03-2018 MSG_RS20250 cebeb2b3bd9a8e5fa7b935e0a9a9e3fb 570 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 13 338 1.1E-129 T 29-03-2018 IPR010839 Acyclic terpene utilisation MSG_RS09070 e05e98e4a4b3c133ed57137fa66a4100 246 Pfam PF12502 Protein of unknown function (DUF3710) 34 203 6.7E-57 T 29-03-2018 IPR022183 Protein of unknown function DUF3710 MSG_RS05345 333270247f6dd0b3902879442f16561a 663 Pfam PF13520 Amino acid permease 63 454 7.1E-20 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MSG_RS16560 9307dc6b595eb89983173ad6b872a285 255 Pfam PF02405 Permease MlaE 38 248 6.9E-56 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MSG_RS12630 0707a6c6208ee20fd714aae190380a14 505 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 18 481 8.6E-151 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS12630 0707a6c6208ee20fd714aae190380a14 505 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 16 493 8.8E-149 T 29-03-2018 IPR007795 Type VII secretion system EccB MSG_RS11325 1343457eaf8bdb1b513448b097ca08ba 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 144 1.6E-34 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ MSG_RS13010 ece148ca8fc73ca55e1af6df2c7a8bda 345 Pfam PF07174 Fibronectin-attachment protein (FAP) 1 307 1.2E-123 T 29-03-2018 IPR010801 Fibronectin-attachment GO:0005576|GO:0050840 MSG_RS10445 614ab5af3554ed4f8debc476412b7429 582 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 576 4.6E-262 T 29-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane MSG_RS21965 29d9edb97d47b769c5f6306babada951 251 PIRSF PIRSF018008 1 249 3.7E-80 T 29-03-2018 IPR008306 Uncharacterised conserved protein UCP018008 MSG_RS21965 29d9edb97d47b769c5f6306babada951 251 Pfam PF04250 Protein of unknown function (DUF429) 5 231 9.1E-38 T 29-03-2018 IPR007362 Protein of unknown function DUF429 MSG_RS16135 d3e0526044782a1d20c4c4af340c863e 120 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 52 88 1.1E-4 T 29-03-2018 IPR022171 PPE family, C-terminal MSG_RS06340 b0d87eab8482990f2797945c1cc56230 993 Hamap MF_01600 UPF0182 protein . 11 904 17.688 T 29-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 MSG_RS06340 b0d87eab8482990f2797945c1cc56230 993 Pfam PF03699 Uncharacterised protein family (UPF0182) 21 820 2.4E-267 T 29-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 MSG_RS13310 f7500c043b027ac50d761735abd26936 133 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 119 5.9E-28 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MSG_RS16990 e2e42a2a81b6107fa5d472e63ca1437f 145 Pfam PF05423 Mycobacterium membrane protein 8 145 1.2E-50 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS18830 9e8192fd9f576d331b9957d07bb0bd9b 224 Pfam PF04191 Phospholipid methyltransferase 110 201 2.1E-13 T 29-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 MSG_RS05715 e2c373d358c65e06c7108d836cb67206 172 Pfam PF03703 Bacterial PH domain 82 154 5.8E-18 T 29-03-2018 IPR005182 Domain of unknown function DUF304 MSG_RS01625 08d62452a29a2b2139510a4e075c5b93 242 Pfam PF02535 ZIP Zinc transporter 95 233 2.9E-10 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MSG_RS13245 b7cf1610085be5855e71515ee7a7c8d6 75 Gene3D G3DSA:1.10.287.700 6 69 5.8E-6 T 29-03-2018 MSG_RS09930 e62c637fec452c7ffe3c5aedc0e5bdf9 237 Gene3D G3DSA:1.20.1250.20 2 176 7.1E-4 T 29-03-2018 MSG_RS01320 1279a6e284d9399690cd140a6d2df7bf 376 Pfam PF00487 Fatty acid desaturase 65 331 7.3E-34 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MSG_RS09210 dbff31c7d15bcab07bb194bea154c1c1 177 Gene3D G3DSA:2.60.40.1240 33 177 6.7E-22 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain MSG_RS08855 46e6b0074960e42239a569d528a98ed0 275 Pfam PF04012 PspA/IM30 family 3 241 5.3E-61 T 29-03-2018 IPR007157 PspA/IM30 MSG_RS19250 119724ef30c30e71cb9b96d70532e8a7 166 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 74 163 1.4E-26 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 MSG_RS03780 deb02dc93964459445b6844467aaf147 112 Pfam PF11829 Protein of unknown function (DUF3349) 4 91 3.2E-32 T 29-03-2018 IPR021784 Protein of unknown function DUF3349 MSG_RS15830 3ea82354a3c7a710f3c41354dd5cdfd8 361 SUPERFAMILY SSF51735 8 111 2.2E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain MSG_RS15830 3ea82354a3c7a710f3c41354dd5cdfd8 361 Gene3D G3DSA:3.40.50.720 2 113 3.8E-14 T 29-03-2018 MSG_RS15830 3ea82354a3c7a710f3c41354dd5cdfd8 361 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 8 84 5.0E-6 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MSG_RS19170 4813f7319b0f815fe06b27423419d7a6 63 Pfam PF17227 Family of unknown function (DUF5302) 13 63 1.4E-19 T 29-03-2018 IPR035172 Protein of unknown function DUF5302 MSG_RS06310 11c7b15b623f3d15e9f684cc5b3d6cb6 89 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 78 15.521 T 29-03-2018 IPR003482 Transcription factor WhiB MSG_RS06310 11c7b15b623f3d15e9f684cc5b3d6cb6 89 Pfam PF02467 Transcription factor WhiB 16 64 3.8E-15 T 29-03-2018 IPR034768 WhiB-like iron-sulfur binding domain MSG_RS02045 cfed426899bf9d41b0d551128e08896e 256 SUPERFAMILY SSF53335 52 217 2.17E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MSG_RS02045 cfed426899bf9d41b0d551128e08896e 256 Gene3D G3DSA:3.40.50.150 9 206 6.1E-22 T 29-03-2018 MSG_RS02045 cfed426899bf9d41b0d551128e08896e 256 Pfam PF08241 Methyltransferase domain 63 155 1.7E-17 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MSG_RS00080 01352f9d9017d672400361ddc7cd4d53 143 Pfam PF10756 Bacterial PH domain 58 135 1.6E-21 T 29-03-2018 IPR019692 Protein of unknown function DUF2581 MSG_RS09655 2e51ec157527b6a2e341779c2bb12d09 203 Pfam PF13785 Domain of unknown function (DUF4178) 55 189 1.6E-33 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 MSG_RS19135 a677d80aeb440a281c5cd20f010618f2 94 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 20.285 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MSG_RS19135 a677d80aeb440a281c5cd20f010618f2 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 90 1.2E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MSG_RS19135 a677d80aeb440a281c5cd20f010618f2 94 Gene3D G3DSA:3.30.1360.20 2 94 2.3E-27 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MSG_RS19135 a677d80aeb440a281c5cd20f010618f2 94 SUPERFAMILY SSF55248 3 92 3.27E-28 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MSG_RS04715 5135d7f64e35b3a693965db151a41228 252 Pfam PF13490 Putative zinc-finger 33 58 4.1E-8 T 29-03-2018 IPR027383 Putative zinc-finger MSG_RS24550 766340a151db59497fedc55796a92371 258 SUPERFAMILY SSF53448 31 181 2.62E-5 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MSG_RS04770 4c75e9757f09cd789b28258799235496 354 Pfam PF01757 Acyltransferase family 12 327 5.4E-18 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS09215 c988019111e548b153944b847b0e3a94 115 Pfam PF05305 Protein of unknown function (DUF732) 7 97 1.4E-27 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS20525 c5a99ff8d5a109a54beea3898db0f954 101 Gene3D G3DSA:1.10.10.620 43 99 1.5E-5 T 29-03-2018 MSG_RS09285 adb3663e63b98d03b88a6e459e00ff89 85 Pfam PF12587 Protein of unknown function (DUF3761) 30 61 5.1E-14 T 29-03-2018 IPR022236 Protein of unknown function DUF3761 MSG_RS08235 34dd349d9a12c21b47f6519c1d0b9f13 101 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 3.1E-52 T 29-03-2018 IPR019592 Protein of unknown function DUF2469 MSG_RS06915 e67a83fb8fa1098865f914cc16ca3816 141 Pfam PF05423 Mycobacterium membrane protein 5 141 4.5E-35 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS02395 b3b507ae10371fccac2f0cd94100360c 292 Pfam PF14011 EspG family 11 266 1.9E-61 T 29-03-2018 IPR025734 EspG family MSG_RS07435 9ac566b289a090aef72c05b70241bb21 106 Pfam PF11829 Protein of unknown function (DUF3349) 10 103 8.2E-31 T 29-03-2018 IPR021784 Protein of unknown function DUF3349 MSG_RS01970 8987144615a91ec7989325f89aebe3a6 150 Pfam PF04505 Interferon-induced transmembrane protein 55 121 1.2E-24 T 29-03-2018 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 MSG_RS01290 c8d842c99b65a088322b464c1b8b14fc 93 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 9 45 2.3E-11 T 29-03-2018 IPR019933 DivIVA domain MSG_RS01290 c8d842c99b65a088322b464c1b8b14fc 93 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 51 84 9.6E-12 T 29-03-2018 IPR019933 DivIVA domain MSG_RS18165 7bf45014979359b473525bbc02b7b39f 556 Pfam PF01061 ABC-2 type transporter 16 222 3.5E-13 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS18165 7bf45014979359b473525bbc02b7b39f 556 Pfam PF01061 ABC-2 type transporter 314 514 3.1E-16 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MSG_RS10415 4c95801b2961357f1d4666d07dc5e5e6 121 Pfam PF05305 Protein of unknown function (DUF732) 6 107 3.6E-23 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS05095 a1503414ffd10be5fedaff6edb2b538d 274 Gene3D G3DSA:1.25.40.10 9 176 2.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MSG_RS05095 a1503414ffd10be5fedaff6edb2b538d 274 Gene3D G3DSA:1.25.40.120 177 244 0.0011 T 29-03-2018 MSG_RS22950 565cdb52086b26f4b8ffca9909d97a7e 111 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 3 106 5.9E-28 T 29-03-2018 IPR019277 Protein of unknown function DUF2304 MSG_RS07610 555730a209445288c83aa270d252a3dc 79 Gene3D G3DSA:3.40.50.720 14 76 5.4E-4 T 29-03-2018 MSG_RS15475 f7d3e5bbc6b5aa440ee91e259beaec49 65 Gene3D G3DSA:3.40.190.10 8 56 4.2E-4 T 29-03-2018 MSG_RS19480 bcd0cdd2aa0dca25918493da6decdbd0 126 Pfam PF05305 Protein of unknown function (DUF732) 5 98 4.4E-23 T 29-03-2018 IPR007969 Domain of unknown function DUF732 MSG_RS23835 8df582550d48c4cf704e64622bac29ca 123 Pfam PF06305 Lipopolysaccharide assembly protein A domain 52 106 3.7E-11 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MSG_RS17915 020a46654275126ddd385a7e25d8461a 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 83 1.5E-23 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MSG_RS03900 e6ec3b61d2df186acc2d8d8a4623c4e8 495 Pfam PF00916 Sulfate permease family 6 356 1.2E-75 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MSG_RS23200 8a698320a22e4788ae6452002eb4b0d1 126 Pfam PF04134 Protein of unknown function, DUF393 6 113 1.6E-18 T 29-03-2018 IPR007263 Protein of unknown function DUF393 MSG_RS04265 4f528bc93649df641439775cd78ea27c 144 Pfam PF11259 Protein of unknown function (DUF3060) 79 137 5.7E-23 T 29-03-2018 IPR021417 Protein of unknown function DUF3060 MSG_RS13825 967c62bdf1cd103a3fe435e9c70ff2e1 144 Pfam PF05423 Mycobacterium membrane protein 9 144 8.2E-54 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS09515 c6260483ef8c8254c7a474d9bec77f10 357 Pfam PF03773 Predicted permease 72 349 1.1E-26 T 29-03-2018 IPR005524 Predicted permease DUF318 MSG_RS23360 a2c0119151c46e96c9a7680a26afed17 215 Pfam PF14032 PknH-like extracellular domain 29 210 1.1E-35 T 29-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MSG_RS10670 71bae4ddd8a16d5d31163cfc260d6182 286 Gene3D G3DSA:3.40.960.10 177 282 1.5E-8 T 29-03-2018 MSG_RS09995 38c6f968c9a013bb83730b5b9a9404b9 341 Pfam PF11927 Protein of unknown function (DUF3445) 63 297 5.5E-48 T 29-03-2018 IPR021848 Protein of unknown function DUF3445 MSG_RS12685 6930148e7456e184d7fb83047e594acc 300 Pfam PF14011 EspG family 14 283 1.6E-44 T 29-03-2018 IPR025734 EspG family MSG_RS18615 b08c6b6602293bae93ec9ec35a54c5ec 81 Pfam PF09851 Short C-terminal domain 52 79 4.7E-10 T 29-03-2018 IPR018649 SHOCT domain MSG_RS16125 bec6a94fe6ef8ed8cff6178432bd3530 38 Pfam PF05901 Excalibur calcium-binding domain 24 35 1.9E-5 T 29-03-2018 IPR008613 Excalibur calcium-binding domain MSG_RS18860 0c9cc58665c9027da7292ce36257ac19 117 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 82 3.6E-12 T 29-03-2018 IPR019933 DivIVA domain MSG_RS03070 fc786ae91d7e887190f778007b94b6f1 148 Pfam PF13828 Domain of unknown function (DUF4190) 50 109 8.1E-20 T 29-03-2018 IPR025241 Domain of unknown function DUF4190 MSG_RS19535 ac4c766c4a14e190a7990234090ab40c 223 Pfam PF14030 Protein of unknown function (DUF4245) 25 213 3.2E-54 T 29-03-2018 IPR025339 Protein of unknown function DUF4245 MSG_RS20385 14d42cd50e470cbd8927b7279539701d 439 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 152 325 6.5E-23 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 MSG_RS22620 286b191fbb3e6875719eff9cb5d74dbd 148 Gene3D G3DSA:1.20.5.900 2 50 1.2E-4 T 29-03-2018 MSG_RS22935 e31ae7e5fcf4f9e14b4d5281445f8353 358 Pfam PF04332 Protein of unknown function (DUF475) 45 353 1.8E-131 T 29-03-2018 IPR007427 Protein of unknown function DUF475 MSG_RS02070 3d26ff3d93d6f8a356fabc4c90aa4b31 159 Pfam PF10722 Putative bacterial sensory transduction regulator 8 137 3.2E-11 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN MSG_RS22470 06f08364d023658771873c1e36bfeedc 279 Gene3D G3DSA:3.40.960.10 177 277 3.6E-9 T 29-03-2018 MSG_RS02625 8638ec8721ff32d595f2c44da23578ff 477 Gene3D G3DSA:3.30.420.40 69 289 1.5E-7 T 29-03-2018 MSG_RS03625 04a233438a9f57aadcc2a24ce2b1d81b 418 Pfam PF01757 Acyltransferase family 11 362 7.5E-24 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 MSG_RS08070 e5056549bb4931f989ee811849099499 187 Pfam PF02620 Uncharacterized ACR, COG1399 56 167 6.7E-29 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MSG_RS03225 b8d20665e4dcb9a97dfee8590b87c5b2 70 Pfam PF16525 Haemophore, haem-binding 31 66 4.0E-8 T 29-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 MSG_RS10880 e903e42e1d3209eec7a7c865aab01ef4 152 Pfam PF05423 Mycobacterium membrane protein 14 152 2.4E-65 T 29-03-2018 IPR008693 Transport accessory protein MmpS MSG_RS01760 e3203180a3306e4d419db26722a1d5fb 308 Pfam PF06271 RDD family 8 130 3.9E-11 T 29-03-2018 IPR010432 RDD MSG_RS01815 47f2b5524d4a33d3e448fa9e7db03019 472 Gene3D G3DSA:3.40.50.1820 53 314 1.6E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold