locus-tag	class	description
MyAD_RS00005	COG1793	dna ligase
MyAD_RS00020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MyAD_RS00025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MyAD_RS00030	COG0765	amino acid transport
MyAD_RS00035	COG1126	abc transporter atp-binding protein
MyAD_RS00040	COG0427	acetyl-CoA hydrolase
MyAD_RS00050	COG0343	queuine tRNA-ribosyltransferase activity
MyAD_RS00075	COG1063	alcohol dehydrogenase
MyAD_RS00145	COG0287	Prephenate dehydrogenase
MyAD_RS00155	COG1174	glycine betaine transport
MyAD_RS00175	COG5416	Lipopolysaccharide assembly protein A domain
MyAD_RS00190	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MyAD_RS00220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MyAD_RS00275	COG0604	alcohol dehydrogenase
MyAD_RS00275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS00275	COG4221	oxidoreductase activity
MyAD_RS00275	COG3321	synthase
MyAD_RS00295	COG1216	Glycosyl transferase, family 2
MyAD_RS00315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MyAD_RS00320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MyAD_RS00335	COG0277	FAD linked oxidase domain protein
MyAD_RS00340	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS00360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MyAD_RS00395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MyAD_RS00400	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MyAD_RS00400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MyAD_RS00400	COG3321	synthase
MyAD_RS00405	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS00410	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MyAD_RS00425	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MyAD_RS00435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MyAD_RS00440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MyAD_RS00445	COG0671	phosphoesterase, PA-phosphatase related
MyAD_RS00450	COG1216	Glycosyl transferase, family 2
MyAD_RS00470	COG0561	phosphatase activity
MyAD_RS00475	COG0204	Acyl-transferase
MyAD_RS00480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MyAD_RS00480	COG2146	nitrite reductase [NAD(P)H] activity
MyAD_RS00500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MyAD_RS00535	COG1316	TRANSCRIPTIONal
MyAD_RS00540	COG1528	Iron-storage protein
MyAD_RS00555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MyAD_RS00605	COG0789	Transcriptional regulator
MyAD_RS00610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MyAD_RS00615	COG2072	flavoprotein involved in K transport
MyAD_RS00620	COG1309	transcriptional regulator
MyAD_RS00625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MyAD_RS00630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MyAD_RS00630	COG1796	DNA polymerase
MyAD_RS00645	COG0069	glutamate synthase activity
MyAD_RS00645	COG0067	glutamate synthase
MyAD_RS00645	COG0070	glutamate synthase
MyAD_RS00655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MyAD_RS00660	COG0783	Belongs to the Dps family
MyAD_RS00680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS00695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MyAD_RS00710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MyAD_RS00740	COG2226	methyltransferase
MyAD_RS00745	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS00770	COG1335	isochorismatase
MyAD_RS00775	COG0789	Transcriptional regulator
MyAD_RS00780	COG0659	secondary active sulfate transmembrane transporter activity
MyAD_RS00795	COG0842	Transport permease protein
MyAD_RS00810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MyAD_RS00815	COG3842	ATPase activity
MyAD_RS00840	COG1022	Amp-dependent synthetase and ligase
MyAD_RS00840	COG3320	Male sterility
MyAD_RS00850	COG3391	amine dehydrogenase activity
MyAD_RS00850	COG5651	PPE family
MyAD_RS00910	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MyAD_RS00925	COG1116	anion transmembrane transporter activity
MyAD_RS00945	COG3961	Belongs to the TPP enzyme family
MyAD_RS00955	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS00960	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS00965	COG2132	Multicopper oxidase
MyAD_RS00970	COG2197	response regulator
MyAD_RS01005	COG1643	Atp-dependent helicase
MyAD_RS01025	COG3384	dioxygenase
MyAD_RS01040	COG1063	alcohol dehydrogenase
MyAD_RS01060	COG1033	growth of symbiont in host cell
MyAD_RS01060	COG2409	Drug exporters of the RND superfamily
MyAD_RS01080	COG3263	regulation of cellular component size
MyAD_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS01160	COG0714	Associated with various cellular activities
MyAD_RS01190	COG2197	response regulator
MyAD_RS01195	COG0778	Nitroreductase
MyAD_RS01225	COG0702	epimerase
MyAD_RS01240	COG1403	HNH endonuclease
MyAD_RS01245	COG1595	DNA-templated transcription, initiation
MyAD_RS01255	COG0488	(ABC) transporter
MyAD_RS01265	COG2030	dehydratase
MyAD_RS01270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MyAD_RS01290	COG0477	Major facilitator Superfamily
MyAD_RS01300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MyAD_RS01300	COG4651	solute:proton antiporter activity
MyAD_RS01320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MyAD_RS01340	COG3011	Protein conserved in bacteria
MyAD_RS01345	COG0187	DNA topoisomerase II activity
MyAD_RS01350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MyAD_RS01380	COG2409	Drug exporters of the RND superfamily
MyAD_RS01400	COG3590	peptidase
MyAD_RS01405	COG1376	ErfK ybiS ycfS ynhG family protein
MyAD_RS01410	COG2814	Major facilitator Superfamily
MyAD_RS01420	COG1937	Protein conserved in bacteria
MyAD_RS01445	COG4122	O-methyltransferase activity
MyAD_RS01465	COG2267	carboxylic ester hydrolase activity
MyAD_RS01490	COG3119	arylsulfatase activity
MyAD_RS01540	COG0300	oxidoreductase activity
MyAD_RS01545	COG3619	membrane
MyAD_RS01575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS01600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS01605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS01615	COG1802	Transcriptional regulator
MyAD_RS01635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MyAD_RS01645	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS01665	COG1309	transcriptional regulator
MyAD_RS01675	COG4521	taurine ABC transporter
MyAD_RS01680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MyAD_RS01695	COG0598	Magnesium transport protein CorA
MyAD_RS01700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MyAD_RS01705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MyAD_RS01715	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS01725	COG0583	DNA-binding transcription factor activity
MyAD_RS01730	COG2814	Major facilitator Superfamily
MyAD_RS01735	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS01740	COG2365	Tyrosine phosphatase family
MyAD_RS01760	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS01770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MyAD_RS01775	COG1309	transcriptional regulator
MyAD_RS01785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MyAD_RS01790	COG1349	DNA-binding transcription factor activity
MyAD_RS01795	COG1105	Belongs to the carbohydrate kinase PfkB family
MyAD_RS01800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MyAD_RS01800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MyAD_RS01810	COG1404	Belongs to the peptidase S8 family
MyAD_RS01840	COG4842	Belongs to the WXG100 family
MyAD_RS01845	COG4842	Belongs to the WXG100 family
MyAD_RS01860	COG1674	ftsk spoiiie
MyAD_RS01875	COG0464	growth
MyAD_RS01895	COG1716	ATPase activity
MyAD_RS01925	COG2354	Protein conserved in bacteria
MyAD_RS01930	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MyAD_RS01940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MyAD_RS01980	COG0456	acetyltransferase
MyAD_RS01995	COG1716	ATPase activity
MyAD_RS02000	COG1716	ATPase activity
MyAD_RS02015	COG0768	penicillin binding
MyAD_RS02020	COG0515	serine threonine protein kinase
MyAD_RS02025	COG0515	serine threonine protein kinase
MyAD_RS02025	COG2815	serine threonine protein kinase
MyAD_RS02090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MyAD_RS02095	COG0187	DNA topoisomerase II activity
MyAD_RS02100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MyAD_RS02105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MyAD_RS02110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MyAD_RS02115	COG0592	DNA-directed DNA polymerase activity
MyAD_RS02125	COG0594	ribonuclease P activity
MyAD_RS02130	COG0706	membrane insertase activity
MyAD_RS02140	COG0357	Ribosomal RNA small subunit methyltransferase G
MyAD_RS02145	COG1192	Involved in chromosome partitioning
MyAD_RS02160	COG3409	Peptidoglycan-binding domain 1 protein
MyAD_RS02160	COG0860	N-Acetylmuramoyl-L-alanine amidase
MyAD_RS02180	COG1595	DNA-templated transcription, initiation
MyAD_RS02200	COG0617	tRNA 3'-terminal CCA addition
MyAD_RS02225	COG1678	Uncharacterized ACR, COG1678
MyAD_RS02240	COG0495	leucyl-tRNA aminoacylation
MyAD_RS02245	COG1063	alcohol dehydrogenase
MyAD_RS02250	COG0300	oxidoreductase activity
MyAD_RS02255	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MyAD_RS02265	COG1126	abc transporter atp-binding protein
MyAD_RS02270	COG0765	amino acid transport
MyAD_RS02275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS02285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MyAD_RS02285	COG0596	Alpha beta hydrolase
MyAD_RS02290	COG1260	myo-inositol-1-phosphate synthase
MyAD_RS02315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MyAD_RS02325	COG0360	Binds together with S18 to 16S ribosomal RNA
MyAD_RS02330	COG0629	single-stranded DNA binding
MyAD_RS02335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MyAD_RS02340	COG0359	binds to the 23S rRNA
MyAD_RS02375	COG3135	benzoate transporter
MyAD_RS02380	COG1396	sequence-specific DNA binding
MyAD_RS02400	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS02415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS02430	COG0456	acetyltransferase
MyAD_RS02460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MyAD_RS02465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MyAD_RS02475	COG0601	transmembrane transport
MyAD_RS02495	COG0363	glucosamine-6-phosphate deaminase activity
MyAD_RS02515	COG0477	Major facilitator Superfamily
MyAD_RS02550	COG0596	Alpha beta hydrolase
MyAD_RS02595	COG2072	flavoprotein involved in K transport
MyAD_RS02610	COG1285	pathogenesis
MyAD_RS02635	COG1072	(Pantothenic acid kinase))
MyAD_RS02640	COG1609	Transcriptional regulator
MyAD_RS02655	COG0644	oxidoreductase
MyAD_RS02665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MyAD_RS02670	COG2301	Belongs to the HpcH HpaI aldolase family
MyAD_RS02675	COG3757	hydrolase, family 25
MyAD_RS02680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MyAD_RS02715	COG2409	Drug exporters of the RND superfamily
MyAD_RS02725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MyAD_RS02740	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MyAD_RS02750	COG0702	epimerase
MyAD_RS02760	COG4221	oxidoreductase activity
MyAD_RS02770	COG0640	Transcriptional regulator
MyAD_RS02780	COG0657	acetylesterase activity
MyAD_RS02785	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS02790	COG0657	acetylesterase activity
MyAD_RS02805	COG0657	acetylesterase activity
MyAD_RS02810	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS02830	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS02845	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS02925	COG4981	capsule polysaccharide biosynthetic process
MyAD_RS02930	COG1472	Belongs to the glycosyl hydrolase 3 family
MyAD_RS02940	COG2030	dehydratase
MyAD_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS02950	COG0183	Belongs to the thiolase family
MyAD_RS02960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS02965	COG1396	sequence-specific DNA binding
MyAD_RS02970	COG0740	serine-type endopeptidase activity
MyAD_RS02975	COG0740	serine-type endopeptidase activity
MyAD_RS02980	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS03005	COG5651	PPE family
MyAD_RS03015	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS03020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MyAD_RS03030	COG1053	succinate dehydrogenase
MyAD_RS03055	COG2146	nitrite reductase [NAD(P)H] activity
MyAD_RS03055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MyAD_RS03080	COG1984	allophanate hydrolase subunit 2
MyAD_RS03085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MyAD_RS03105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MyAD_RS03110	COG2957	Belongs to the agmatine deiminase family
MyAD_RS03115	COG1764	response to oxidative stress
MyAD_RS03120	COG1846	Transcriptional regulator
MyAD_RS03125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS03130	COG1063	alcohol dehydrogenase
MyAD_RS03140	COG1309	transcriptional regulator
MyAD_RS03190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS03245	COG1454	alcohol dehydrogenase
MyAD_RS03245	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS03250	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MyAD_RS03270	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MyAD_RS03295	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MyAD_RS03320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS03325	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS03345	COG0477	Major facilitator Superfamily
MyAD_RS03360	COG0803	Belongs to the bacterial solute-binding protein 9 family
MyAD_RS03365	COG1121	(ABC) transporter
MyAD_RS03370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MyAD_RS03380	COG0596	Alpha beta hydrolase
MyAD_RS03390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MyAD_RS03410	COG0583	DNA-binding transcription factor activity
MyAD_RS03425	COG3958	Transketolase
MyAD_RS03430	COG3959	Transketolase, thiamine diphosphate binding domain
MyAD_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS03450	COG2376	Dihydroxyacetone kinase
MyAD_RS03455	COG0698	ribose 5-phosphate isomerase
MyAD_RS03465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MyAD_RS03465	COG0352	thiamine-phosphate diphosphorylase activity
MyAD_RS03465	COG0351	phosphomethylpyrimidine kinase
MyAD_RS03470	COG0693	protein deglycase activity
MyAD_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS03555	COG1129	ABC transporter
MyAD_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
MyAD_RS03565	COG3467	pyridoxamine 5'-phosphate
MyAD_RS03585	COG2144	transferase activity, transferring acyl groups
MyAD_RS03595	COG2072	flavoprotein involved in K transport
MyAD_RS03605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MyAD_RS03625	COG1309	transcriptional regulator
MyAD_RS03645	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS03655	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS03675	COG0346	lactoylglutathione lyase activity
MyAD_RS03690	COG0464	growth
MyAD_RS03695	COG3266	domain, Protein
MyAD_RS03700	COG1674	ftsk spoiiie
MyAD_RS03720	COG4842	Belongs to the WXG100 family
MyAD_RS03735	COG1404	Belongs to the peptidase S8 family
MyAD_RS03755	COG4106	trans-aconitate 2-methyltransferase activity
MyAD_RS03770	COG4424	Sulfotransferase
MyAD_RS03775	COG3119	arylsulfatase activity
MyAD_RS03780	COG0494	nUDIX hydrolase
MyAD_RS03795	COG0671	phosphoesterase, PA-phosphatase related
MyAD_RS03820	COG3800	Transcriptional regulator
MyAD_RS03820	COG1396	sequence-specific DNA binding
MyAD_RS03830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MyAD_RS03905	COG0243	molybdopterin cofactor binding
MyAD_RS03925	COG1522	sequence-specific DNA binding
MyAD_RS03955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MyAD_RS03960	COG3387	PFAM Glycoside hydrolase 15-related
MyAD_RS03975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MyAD_RS03985	COG0604	alcohol dehydrogenase
MyAD_RS03990	COG0747	negative chemotaxis
MyAD_RS03995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MyAD_RS04000	COG0601	transmembrane transport
MyAD_RS04005	COG0444	Belongs to the ABC transporter superfamily
MyAD_RS04010	COG4608	Belongs to the ABC transporter superfamily
MyAD_RS04040	COG3550	peptidyl-serine autophosphorylation
MyAD_RS04185	COG0717	Belongs to the dCTP deaminase family
MyAD_RS04195	COG2267	carboxylic ester hydrolase activity
MyAD_RS04240	COG0247	lactate metabolic process
MyAD_RS04240	COG2181	nitrate reductase activity
MyAD_RS04300	COG4399	Belongs to the UPF0754 family
MyAD_RS04315	COG0443	Heat shock 70 kDa protein
MyAD_RS04320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MyAD_RS04325	COG0484	heat shock protein binding
MyAD_RS04330	COG0789	Transcriptional regulator
MyAD_RS04410	COG0542	response to heat
MyAD_RS04445	COG0477	Major facilitator Superfamily
MyAD_RS04450	COG1309	transcriptional regulator
MyAD_RS04455	COG0586	Pfam SNARE associated Golgi protein
MyAD_RS04485	COG1994	Peptidase M50
MyAD_RS04495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MyAD_RS04525	COG2124	cytochrome p450
MyAD_RS04530	COG0596	Alpha beta hydrolase
MyAD_RS04535	COG2409	Drug exporters of the RND superfamily
MyAD_RS04545	COG0025	NhaP-type Na H and K H
MyAD_RS04580	COG0583	DNA-binding transcription factor activity
MyAD_RS04590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS04595	COG4221	oxidoreductase activity
MyAD_RS04605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS04620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MyAD_RS04625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS04630	COG2188	Transcriptional regulator
MyAD_RS04650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS04660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MyAD_RS04665	COG0515	serine threonine protein kinase
MyAD_RS04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MyAD_RS04685	COG0352	thiamine-phosphate diphosphorylase activity
MyAD_RS04690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS04690	COG2022	thiamine diphosphate biosynthetic process
MyAD_RS04700	COG2022	thiamine diphosphate biosynthetic process
MyAD_RS04715	COG2234	aminopeptidase activity
MyAD_RS04720	COG2234	aminopeptidase activity
MyAD_RS04725	COG2409	Drug exporters of the RND superfamily
MyAD_RS04735	COG1755	Isoprenylcysteine carboxyl methyltransferase
MyAD_RS04745	COG2233	PERMEase
MyAD_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS04775	COG2072	flavoprotein involved in K transport
MyAD_RS04790	COG0351	phosphomethylpyrimidine kinase
MyAD_RS04795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MyAD_RS04800	COG2814	Major facilitator Superfamily
MyAD_RS04860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MyAD_RS04870	COG2226	methyltransferase
MyAD_RS04890	COG0542	response to heat
MyAD_RS04905	COG0242	peptide deformylase activity
MyAD_RS04920	COG2032	superoxide dismutase activity
MyAD_RS04940	COG1320	monovalent cation:proton antiporter activity
MyAD_RS04945	COG2212	antiporter activity
MyAD_RS04955	COG0651	ATP synthesis coupled electron transport
MyAD_RS04960	COG1006	Multisubunit Na H antiporter MnhC subunit
MyAD_RS04965	COG2111	Na H antiporter
MyAD_RS04965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MyAD_RS04970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MyAD_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS04995	COG1024	Enoyl-CoA hydratase
MyAD_RS05000	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS05005	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS05040	COG0647	UMP catabolic process
MyAD_RS05055	COG4221	oxidoreductase activity
MyAD_RS05065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MyAD_RS05070	COG1116	anion transmembrane transporter activity
MyAD_RS05075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MyAD_RS05080	COG0459	protein refolding
MyAD_RS05095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MyAD_RS05110	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS05115	COG2326	polyphosphate kinase activity
MyAD_RS05140	COG1505	serine-type exopeptidase activity
MyAD_RS05150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS05155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS05200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS05205	COG2326	polyphosphate kinase activity
MyAD_RS05215	COG2733	membrane
MyAD_RS05280	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS05290	COG0588	phosphoglycerate mutase activity
MyAD_RS05295	COG5002	protein histidine kinase activity
MyAD_RS05300	COG0745	RESPONSE REGULATOR receiver
MyAD_RS05375	COG0181	hydroxymethylbilane synthase activity
MyAD_RS05380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MyAD_RS05440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MyAD_RS05445	COG0406	alpha-ribazole phosphatase activity
MyAD_RS05455	COG0785	Cytochrome C biogenesis protein
MyAD_RS05465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MyAD_RS05470	COG2894	cell division
MyAD_RS05505	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MyAD_RS05510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MyAD_RS05545	COG2070	2-Nitropropane dioxygenase
MyAD_RS05565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MyAD_RS05650	COG0531	amino acid
MyAD_RS05655	COG0300	oxidoreductase activity
MyAD_RS05680	COG4221	oxidoreductase activity
MyAD_RS05690	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MyAD_RS05710	COG4552	Acetyltransferase involved in intracellular survival and related
MyAD_RS05725	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS05735	COG1228	amidohydrolase
MyAD_RS05740	COG4948	Mandelate Racemase Muconate Lactonizing
MyAD_RS05750	COG4977	sequence-specific DNA binding
MyAD_RS05765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MyAD_RS05780	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS05830	COG1100	Small GTP-binding protein
MyAD_RS05865	COG4221	oxidoreductase activity
MyAD_RS05870	COG2226	methyltransferase
MyAD_RS05875	COG0523	cobalamin synthesis protein
MyAD_RS05895	COG0235	Class ii aldolase
MyAD_RS05905	COG3123	guanosine phosphorylase activity
MyAD_RS05915	COG0644	oxidoreductase
MyAD_RS05920	COG0142	geranyltranstransferase activity
MyAD_RS05925	COG0501	Belongs to the peptidase M48B family
MyAD_RS05945	COG1666	GTP binding
MyAD_RS06025	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS06040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MyAD_RS06045	COG1074	ATP-dependent DNA helicase activity
MyAD_RS06050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MyAD_RS06065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MyAD_RS06090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MyAD_RS06095	COG1959	2 iron, 2 sulfur cluster binding
MyAD_RS06120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MyAD_RS06130	COG2030	dehydratase
MyAD_RS06145	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MyAD_RS06155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MyAD_RS06160	COG0081	regulation of translation
MyAD_RS06170	COG1088	dTDP-glucose 4,6-dehydratase activity
MyAD_RS06215	COG0489	protein tyrosine kinase activity
MyAD_RS06235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS06240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS06300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MyAD_RS06305	COG0222	ribosome binding
MyAD_RS06315	COG0085	RNA polymerase activity
MyAD_RS06320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MyAD_RS06345	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS06380	COG1309	transcriptional regulator
MyAD_RS06385	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MyAD_RS06395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MyAD_RS06400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MyAD_RS06425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MyAD_RS06430	COG1834	amidinotransferase
MyAD_RS06435	COG1522	sequence-specific DNA binding
MyAD_RS06460	COG0535	radical SAM domain protein
MyAD_RS06490	COG0477	Major facilitator Superfamily
MyAD_RS06505	COG2272	Belongs to the type-B carboxylesterase lipase family
MyAD_RS06515	COG0051	transcription antitermination factor activity, RNA binding
MyAD_RS06520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MyAD_RS06525	COG0088	Forms part of the polypeptide exit tunnel
MyAD_RS06535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MyAD_RS06540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MyAD_RS06545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MyAD_RS06555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MyAD_RS06565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MyAD_RS06605	COG3619	membrane
MyAD_RS06610	COG3069	C4-dicarboxylate transmembrane transporter activity
MyAD_RS06645	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS06655	COG0405	Gamma-glutamyltransferase
MyAD_RS06670	COG0154	amidase activity
MyAD_RS06675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MyAD_RS06690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MyAD_RS06700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MyAD_RS06705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MyAD_RS06710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MyAD_RS06715	COG1841	ribosomal large subunit assembly
MyAD_RS06720	COG0200	Binds to the 23S rRNA
MyAD_RS06725	COG0616	signal peptide processing
MyAD_RS06730	COG2197	response regulator
MyAD_RS06740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MyAD_RS06755	COG1366	Belongs to the anti-sigma-factor antagonist family
MyAD_RS06760	COG0477	Major facilitator Superfamily
MyAD_RS06765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MyAD_RS06770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MyAD_RS06800	COG0563	adenylate kinase activity
MyAD_RS06815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MyAD_RS06830	COG2197	response regulator
MyAD_RS06855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MyAD_RS06860	COG1088	dTDP-glucose 4,6-dehydratase activity
MyAD_RS06875	COG3852	Histidine kinase
MyAD_RS06880	COG0492	ferredoxin-NADP+ reductase activity
MyAD_RS06900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MyAD_RS06905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MyAD_RS06910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MyAD_RS06915	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MyAD_RS06920	COG0202	RNA polymerase activity
MyAD_RS06925	COG0203	ribosomal protein L17
MyAD_RS06955	COG5006	permease, DMT superfamily
MyAD_RS06965	COG3268	Saccharopine dehydrogenase
MyAD_RS06995	COG0142	geranyltranstransferase activity
MyAD_RS07005	COG1404	Belongs to the peptidase S8 family
MyAD_RS07025	COG4842	Belongs to the WXG100 family
MyAD_RS07030	COG4842	Belongs to the WXG100 family
MyAD_RS07045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MyAD_RS07055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MyAD_RS07070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MyAD_RS07075	COG2197	response regulator
MyAD_RS07115	COG0531	amino acid
MyAD_RS07120	COG4303	Ethanolamine ammonia lyase large subunit
MyAD_RS07135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MyAD_RS07140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MyAD_RS07165	COG0513	Belongs to the DEAD box helicase family
MyAD_RS07170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS07180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MyAD_RS07195	COG2814	Major facilitator Superfamily
MyAD_RS07205	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MyAD_RS07220	COG1349	DNA-binding transcription factor activity
MyAD_RS07225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MyAD_RS07225	COG2213	PTS system mannitol-specific
MyAD_RS07230	COG1063	alcohol dehydrogenase
MyAD_RS07245	COG0076	glutamate decarboxylase activity
MyAD_RS07250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MyAD_RS07270	COG0456	acetyltransferase
MyAD_RS07275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MyAD_RS07290	COG1113	amino acid transport
MyAD_RS07310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MyAD_RS07365	COG0516	GMP reductase activity
MyAD_RS07390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MyAD_RS07395	COG0519	Catalyzes the synthesis of GMP from XMP
MyAD_RS07395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MyAD_RS07410	COG0657	acetylesterase activity
MyAD_RS07445	COG4221	oxidoreductase activity
MyAD_RS07450	COG1280	lysine exporter protein (LysE YggA)
MyAD_RS07465	COG0789	Transcriptional regulator
MyAD_RS07475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS07480	COG1120	ATPase activity
MyAD_RS07500	COG0753	catalase activity
MyAD_RS07520	COG0493	'glutamate synthase
MyAD_RS07520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MyAD_RS07525	COG4689	acetoacetate decarboxylase
MyAD_RS07530	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS07540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS07550	COG0179	Fumarylacetoacetate (FAA) hydrolase
MyAD_RS07560	COG0730	response to heat
MyAD_RS07585	COG1937	Protein conserved in bacteria
MyAD_RS07600	COG2030	dehydratase
MyAD_RS07635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MyAD_RS07650	COG2018	Roadblock/LC7 domain
MyAD_RS07665	COG1357	PFAM Pentapeptide repeats (8 copies)
MyAD_RS07670	COG1131	(ABC) transporter
MyAD_RS07670	COG1716	ATPase activity
MyAD_RS07670	COG0842	Transport permease protein
MyAD_RS07700	COG2873	o-acetylhomoserine
MyAD_RS07715	COG0708	Exodeoxyribonuclease III
MyAD_RS07730	COG1295	ribonuclease BN
MyAD_RS07740	COG2070	2-Nitropropane dioxygenase
MyAD_RS07745	COG1686	Belongs to the peptidase S11 family
MyAD_RS07750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MyAD_RS07775	COG1595	DNA-templated transcription, initiation
MyAD_RS07795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MyAD_RS07810	COG2009	succinate dehydrogenase
MyAD_RS07850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MyAD_RS07860	COG3180	Ammonia monooxygenase
MyAD_RS07885	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MyAD_RS07885	COG1473	amidohydrolase
MyAD_RS07905	COG0564	pseudouridine synthase activity
MyAD_RS07925	COG1309	transcriptional regulator
MyAD_RS07945	COG1201	RNA secondary structure unwinding
MyAD_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS07980	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS07990	COG1522	sequence-specific DNA binding
MyAD_RS08010	COG0640	Transcriptional regulator
MyAD_RS08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS08075	COG4770	biotin carboxylase activity
MyAD_RS08110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MyAD_RS08115	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS08125	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS08155	COG0489	protein tyrosine kinase activity
MyAD_RS08185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MyAD_RS08220	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS08235	COG1316	TRANSCRIPTIONal
MyAD_RS08265	COG0778	Nitroreductase
MyAD_RS08265	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MyAD_RS08290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MyAD_RS08300	COG1482	cell wall glycoprotein biosynthetic process
MyAD_RS08305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MyAD_RS08330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MyAD_RS08350	COG0745	RESPONSE REGULATOR receiver
MyAD_RS08355	COG5002	protein histidine kinase activity
MyAD_RS08360	COG5401	PFAM Sporulation and spore germination
MyAD_RS08370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MyAD_RS08390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MyAD_RS08410	COG1162	GTPase activity
MyAD_RS08415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MyAD_RS08420	COG2135	peptidase activity
MyAD_RS08430	COG2226	methyltransferase
MyAD_RS08440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MyAD_RS08445	COG1595	DNA-templated transcription, initiation
MyAD_RS08450	COG5662	AntiSigma factor
MyAD_RS08470	COG1597	lipid kinase activity
MyAD_RS08480	COG3012	SEC-C Motif Domain Protein
MyAD_RS08485	COG0583	DNA-binding transcription factor activity
MyAD_RS08490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS08495	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS08500	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS08505	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MyAD_RS08525	COG0406	alpha-ribazole phosphatase activity
MyAD_RS08540	COG0513	Belongs to the DEAD box helicase family
MyAD_RS08585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MyAD_RS08590	COG0596	Alpha beta hydrolase
MyAD_RS08610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MyAD_RS08620	COG0183	Belongs to the thiolase family
MyAD_RS08635	COG1414	Transcriptional regulator
MyAD_RS08650	COG0145	ligase activity
MyAD_RS08660	COG0145	ligase activity
MyAD_RS08685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MyAD_RS08700	COG3480	Lon protease (S16) C-terminal proteolytic domain
MyAD_RS08705	COG1615	UPF0182 protein
MyAD_RS08740	COG0582	viral genome integration into host DNA
MyAD_RS08820	COG1074	ATP-dependent DNA helicase activity
MyAD_RS08825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MyAD_RS08830	COG1316	TRANSCRIPTIONal
MyAD_RS08835	COG0346	lactoylglutathione lyase activity
MyAD_RS08875	COG0583	DNA-binding transcription factor activity
MyAD_RS08900	COG1454	alcohol dehydrogenase
MyAD_RS08930	COG5001	Diguanylate cyclase
MyAD_RS08945	COG1408	metallophosphoesterase
MyAD_RS08990	COG2208	phosphoserine phosphatase activity
MyAD_RS08990	COG2770	Histidine kinase
MyAD_RS09020	COG2199	diguanylate cyclase activity
MyAD_RS09025	COG1295	ribonuclease BN
MyAD_RS09035	COG4221	oxidoreductase activity
MyAD_RS09040	COG3622	Belongs to the hyi family
MyAD_RS09045	COG1408	metallophosphoesterase
MyAD_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS09075	COG3158	transport of potassium into the cell
MyAD_RS09105	COG1309	transcriptional regulator
MyAD_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS09225	COG0657	acetylesterase activity
MyAD_RS09245	COG0713	ATP synthesis coupled electron transport
MyAD_RS09255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MyAD_RS09260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MyAD_RS09265	COG1034	ATP synthesis coupled electron transport
MyAD_RS09285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MyAD_RS09290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MyAD_RS09340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MyAD_RS09345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS09365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MyAD_RS09370	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09380	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MyAD_RS09385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS09390	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09400	COG0483	inositol monophosphate 1-phosphatase activity
MyAD_RS09420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MyAD_RS09425	COG0668	transmembrane transport
MyAD_RS09435	COG2884	Cell division ATP-binding protein ftsE
MyAD_RS09440	COG2177	Part of the ABC transporter FtsEX involved in
MyAD_RS09445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MyAD_RS09470	COG3285	dna ligase
MyAD_RS09470	COG1793	dna ligase
MyAD_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS09515	COG1309	transcriptional regulator
MyAD_RS09545	COG0270	DNA (cytosine-5-)-methyltransferase activity
MyAD_RS09555	COG0210	DNA helicase
MyAD_RS09575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MyAD_RS09590	COG1201	RNA secondary structure unwinding
MyAD_RS09630	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MyAD_RS09635	COG0668	transmembrane transport
MyAD_RS09640	COG3654	unkown
MyAD_RS09650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MyAD_RS09680	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MyAD_RS09685	COG1605	Chorismate mutase
MyAD_RS09690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MyAD_RS09690	COG2190	(PTS) system
MyAD_RS09690	COG1263	PTS System
MyAD_RS09695	COG2190	(PTS) system
MyAD_RS09700	COG0363	glucosamine-6-phosphate deaminase activity
MyAD_RS09705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MyAD_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS09740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MyAD_RS09745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MyAD_RS09765	COG0477	Major facilitator Superfamily
MyAD_RS09780	COG1309	transcriptional regulator
MyAD_RS09815	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MyAD_RS09820	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MyAD_RS09825	COG1132	(ABC) transporter
MyAD_RS09830	COG1132	(ABC) transporter
MyAD_RS09855	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09860	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09890	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09900	COG0183	Belongs to the thiolase family
MyAD_RS09905	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS09910	COG1802	Transcriptional regulator
MyAD_RS09920	COG1966	Carbon starvation protein
MyAD_RS09975	COG0069	glutamate synthase activity
MyAD_RS09975	COG0070	glutamate synthase
MyAD_RS09975	COG0067	glutamate synthase
MyAD_RS09980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MyAD_RS10005	COG0431	NADPH-dependent FMN reductase
MyAD_RS10015	COG1780	Probably involved in ribonucleotide reductase function
MyAD_RS10045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MyAD_RS10085	COG1309	transcriptional regulator
MyAD_RS10090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MyAD_RS10110	COG2197	response regulator
MyAD_RS10120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MyAD_RS10125	COG2080	2 iron, 2 sulfur cluster binding
MyAD_RS10130	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MyAD_RS10150	COG1064	alcohol dehydrogenase
MyAD_RS10170	COG3830	Belongs to the UPF0237 family
MyAD_RS10170	COG0560	Phosphoserine phosphatase
MyAD_RS10175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MyAD_RS10185	COG2364	Membrane
MyAD_RS10190	COG1119	ATPase activity
MyAD_RS10220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MyAD_RS10225	COG0110	maltose O-acetyltransferase activity
MyAD_RS10245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MyAD_RS10255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MyAD_RS10275	COG0482	sulfurtransferase activity
MyAD_RS10285	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS10290	COG0596	Alpha beta hydrolase
MyAD_RS10310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MyAD_RS10320	COG3766	membrane
MyAD_RS10345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MyAD_RS10350	COG0154	amidase activity
MyAD_RS10355	COG0028	Belongs to the TPP enzyme family
MyAD_RS10365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MyAD_RS10390	COG0440	acetolactate synthase activity
MyAD_RS10420	COG0473	3-isopropylmalate dehydrogenase activity
MyAD_RS10430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MyAD_RS10435	COG0450	alkyl hydroperoxide reductase
MyAD_RS10440	COG2271	Major facilitator Superfamily
MyAD_RS10445	COG0179	Fumarylacetoacetate (FAA) hydrolase
MyAD_RS10450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MyAD_RS10480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MyAD_RS10495	COG0406	alpha-ribazole phosphatase activity
MyAD_RS10495	COG0494	nUDIX hydrolase
MyAD_RS10500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MyAD_RS10505	COG1920	GTP binding
MyAD_RS10515	COG0626	cystathionine gamma-synthase activity
MyAD_RS10520	COG1181	Belongs to the D-alanine--D-alanine ligase family
MyAD_RS10540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MyAD_RS10545	COG1461	Dihydroxyacetone kinase
MyAD_RS10560	COG2119	membrane
MyAD_RS10570	COG1366	Belongs to the anti-sigma-factor antagonist family
MyAD_RS10575	COG1215	transferase activity, transferring glycosyl groups
MyAD_RS10580	COG2208	phosphoserine phosphatase activity
MyAD_RS10600	COG1376	ErfK ybiS ycfS ynhG family protein
MyAD_RS10635	COG0656	L-ascorbic acid biosynthetic process
MyAD_RS10640	COG0656	L-ascorbic acid biosynthetic process
MyAD_RS10645	COG0657	acetylesterase activity
MyAD_RS10665	COG0742	ribosomal rna small subunit methyltransferase
MyAD_RS10670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MyAD_RS10690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS10700	COG0571	ribonuclease III activity
MyAD_RS10705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MyAD_RS10725	COG1196	nuclear chromosome segregation
MyAD_RS10760	COG1304	FMN binding
MyAD_RS10780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MyAD_RS10785	COG3383	formate dehydrogenase (NAD+) activity
MyAD_RS10790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MyAD_RS10800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MyAD_RS10805	COG1686	Belongs to the peptidase S11 family
MyAD_RS10810	COG1686	Belongs to the peptidase S11 family
MyAD_RS10815	COG0367	asparagine synthase
MyAD_RS10820	COG1181	Belongs to the D-alanine--D-alanine ligase family
MyAD_RS10820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MyAD_RS10825	COG1363	Peptidase, m42
MyAD_RS10890	COG0412	Dienelactone hydrolase
MyAD_RS10900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS10905	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS10910	COG3842	ATPase activity
MyAD_RS10980	COG4974	Belongs to the 'phage' integrase family
MyAD_RS10990	COG0052	Belongs to the universal ribosomal protein uS2 family
MyAD_RS10995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MyAD_RS11000	COG0154	amidase activity
MyAD_RS11015	COG0528	UMP kinase activity
MyAD_RS11030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MyAD_RS11040	COG1472	Belongs to the glycosyl hydrolase 3 family
MyAD_RS11050	COG0531	amino acid
MyAD_RS11070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MyAD_RS11075	COG0750	zinc metalloprotease
MyAD_RS11085	COG0456	acetyltransferase
MyAD_RS11090	COG0768	penicillin binding
MyAD_RS11125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MyAD_RS11130	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS11140	COG2186	Transcriptional regulator
MyAD_RS11150	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MyAD_RS11190	COG1648	precorrin-2 dehydrogenase activity
MyAD_RS11190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MyAD_RS11205	COG0442	prolyl-tRNA aminoacylation
MyAD_RS11220	COG0779	Required for maturation of 30S ribosomal subunits
MyAD_RS11230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MyAD_RS11230	COG0481	GTPase activity
MyAD_RS11240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MyAD_RS11255	COG1116	anion transmembrane transporter activity
MyAD_RS11265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MyAD_RS11270	COG1609	Transcriptional regulator
MyAD_RS11275	COG0673	inositol 2-dehydrogenase activity
MyAD_RS11290	COG1929	Belongs to the glycerate kinase type-1 family
MyAD_RS11295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MyAD_RS11300	COG1172	Belongs to the binding-protein-dependent transport system permease family
MyAD_RS11310	COG2390	Transcriptional regulator
MyAD_RS11315	COG1069	ribulokinase activity
MyAD_RS11320	COG1063	alcohol dehydrogenase
MyAD_RS11325	COG1879	ABC-type sugar transport system periplasmic component
MyAD_RS11330	COG1024	Enoyl-CoA hydratase
MyAD_RS11355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MyAD_RS11360	COG2977	Belongs to the P-Pant transferase superfamily
MyAD_RS11385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MyAD_RS11395	COG1185	polyribonucleotide nucleotidyltransferase activity
MyAD_RS11410	COG0686	Belongs to the AlaDH PNT family
MyAD_RS11415	COG1522	sequence-specific DNA binding
MyAD_RS11435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MyAD_RS11460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MyAD_RS11470	COG3214	Protein conserved in bacteria
MyAD_RS11475	COG3300	MHYT domain
MyAD_RS11475	COG5001	Diguanylate cyclase
MyAD_RS11480	COG4221	oxidoreductase activity
MyAD_RS11510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MyAD_RS11515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MyAD_RS11535	COG0659	secondary active sulfate transmembrane transporter activity
MyAD_RS11540	COG1674	ftsk spoiiie
MyAD_RS11545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MyAD_RS11555	COG1396	sequence-specific DNA binding
MyAD_RS11560	COG1842	Phage shock protein A
MyAD_RS11575	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MyAD_RS11595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MyAD_RS11600	COG2137	regulation of response to DNA damage stimulus
MyAD_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS11625	COG2814	Major facilitator Superfamily
MyAD_RS11630	COG0765	amino acid transport
MyAD_RS11635	COG0765	amino acid transport
MyAD_RS11640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MyAD_RS11645	COG1126	abc transporter atp-binding protein
MyAD_RS11650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MyAD_RS11660	COG1196	nuclear chromosome segregation
MyAD_RS11665	COG0697	spore germination
MyAD_RS11675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MyAD_RS11685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MyAD_RS11690	COG5651	PPE family
MyAD_RS11690	COG3391	amine dehydrogenase activity
MyAD_RS11705	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS11720	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS11730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MyAD_RS11735	COG1764	response to oxidative stress
MyAD_RS11740	COG1846	Transcriptional regulator
MyAD_RS11745	COG1388	LysM domain
MyAD_RS11750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MyAD_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS11840	COG0483	inositol monophosphate 1-phosphatase activity
MyAD_RS11860	COG0756	dUTP diphosphatase activity
MyAD_RS11890	COG0569	domain protein
MyAD_RS11895	COG0531	amino acid
MyAD_RS11900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MyAD_RS11925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MyAD_RS11930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MyAD_RS11950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MyAD_RS11960	COG3253	May function as heme-dependent peroxidase
MyAD_RS11970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MyAD_RS11985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MyAD_RS11985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MyAD_RS12020	COG2226	methyltransferase
MyAD_RS12030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MyAD_RS12085	COG2801	Transposase and inactivated derivatives
MyAD_RS12145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MyAD_RS12150	COG2267	carboxylic ester hydrolase activity
MyAD_RS12165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS12170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS12180	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MyAD_RS12185	COG0058	SHG alpha-glucan phosphorylase activity
MyAD_RS12195	COG4762	Protein conserved in bacteria
MyAD_RS12220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MyAD_RS12225	COG1560	Kdo2-lipid A biosynthetic process
MyAD_RS12230	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS12240	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MyAD_RS12245	COG1946	Acyl-CoA thioesterase
MyAD_RS12250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MyAD_RS12255	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS12260	COG0217	transcriptional regulatory protein
MyAD_RS12265	COG0702	epimerase
MyAD_RS12280	COG2255	four-way junction helicase activity
MyAD_RS12310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MyAD_RS12315	COG0747	negative chemotaxis
MyAD_RS12325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MyAD_RS12335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MyAD_RS12345	COG0124	histidyl-tRNA synthetase
MyAD_RS12350	COG1490	D-aminoacyl-tRNA deacylase activity
MyAD_RS12360	COG0411	ABC transporter
MyAD_RS12375	COG0683	leucine binding
MyAD_RS12405	COG1309	transcriptional regulator
MyAD_RS12430	COG2272	Belongs to the type-B carboxylesterase lipase family
MyAD_RS12440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MyAD_RS12450	COG0183	Belongs to the thiolase family
MyAD_RS12520	COG0432	Pfam Uncharacterised protein family UPF0047
MyAD_RS12525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MyAD_RS12530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MyAD_RS12540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MyAD_RS12550	COG1929	Belongs to the glycerate kinase type-1 family
MyAD_RS12555	COG1609	Transcriptional regulator
MyAD_RS12590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MyAD_RS12600	COG0006	proline dipeptidase activity
MyAD_RS12605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MyAD_RS12610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MyAD_RS12620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MyAD_RS12635	COG1403	HNH endonuclease
MyAD_RS12640	COG2188	Transcriptional regulator
MyAD_RS12655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MyAD_RS12675	COG0477	Major facilitator Superfamily
MyAD_RS12680	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MyAD_RS12685	COG0540	Belongs to the ATCase OTCase family
MyAD_RS12700	COG0505	Belongs to the CarA family
MyAD_RS12705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MyAD_RS12710	COG0284	orotidine-5'-phosphate decarboxylase activity
MyAD_RS12725	COG1758	RNA polymerase activity
MyAD_RS12740	COG2072	flavoprotein involved in K transport
MyAD_RS12750	COG0657	acetylesterase activity
MyAD_RS12770	COG1704	LemA family
MyAD_RS12775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MyAD_RS12820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS12820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MyAD_RS12855	COG0477	Major facilitator Superfamily
MyAD_RS12880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MyAD_RS12880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MyAD_RS12885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MyAD_RS12895	COG3153	acetyltransferase
MyAD_RS12895	COG0456	acetyltransferase
MyAD_RS12905	COG1365	unkown
MyAD_RS12910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MyAD_RS12915	COG0322	excinuclease ABC activity
MyAD_RS12920	COG1660	Displays ATPase and GTPase activities
MyAD_RS12935	COG1132	(ABC) transporter
MyAD_RS12940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MyAD_RS12945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MyAD_RS12950	COG0126	phosphoglycerate kinase activity
MyAD_RS12955	COG0149	triose-phosphate isomerase activity
MyAD_RS12965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MyAD_RS13000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MyAD_RS13010	COG0109	protoheme IX farnesyltransferase activity
MyAD_RS13015	COG1301	dicarboxylic acid transport
MyAD_RS13040	COG3842	ATPase activity
MyAD_RS13045	COG0395	ABC-type sugar transport system, permease component
MyAD_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS13065	COG1070	Carbohydrate kinase
MyAD_RS13070	COG0434	BtpA family
MyAD_RS13075	COG0483	inositol monophosphate 1-phosphatase activity
MyAD_RS13080	COG1349	DNA-binding transcription factor activity
MyAD_RS13125	COG0396	ATPase activity
MyAD_RS13140	COG2151	metal-sulfur cluster biosynthetic enzyme
MyAD_RS13150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MyAD_RS13160	COG0488	(ABC) transporter
MyAD_RS13170	COG1309	transcriptional regulator
MyAD_RS13175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MyAD_RS13185	COG0791	NLP P60 protein
MyAD_RS13185	COG3883	PFAM NLP P60 protein
MyAD_RS13195	COG0714	Associated with various cellular activities
MyAD_RS13205	COG2304	oxidoreductase activity
MyAD_RS13210	COG0667	Aldo Keto reductase
MyAD_RS13215	COG2207	Transcriptional regulator
MyAD_RS13225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MyAD_RS13230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MyAD_RS13275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MyAD_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS13280	COG3321	synthase
MyAD_RS13280	COG0604	alcohol dehydrogenase
MyAD_RS13340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MyAD_RS13345	COG2501	S4 domain
MyAD_RS13355	COG0252	asparaginase activity
MyAD_RS13360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MyAD_RS13380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MyAD_RS13390	COG1051	belongs to the nudix hydrolase family
MyAD_RS13420	COG0789	Transcriptional regulator
MyAD_RS13460	COG0156	8-amino-7-oxononanoate synthase activity
MyAD_RS13475	COG1309	transcriptional regulator
MyAD_RS13480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MyAD_RS13520	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS13525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS13530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS13555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS13585	COG3383	formate dehydrogenase (NAD+) activity
MyAD_RS13590	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS13600	COG2124	cytochrome p450
MyAD_RS13620	COG2197	response regulator
MyAD_RS13635	COG1280	lysine exporter protein (LysE YggA)
MyAD_RS13650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MyAD_RS13655	COG0131	Imidazoleglycerol-phosphate dehydratase
MyAD_RS13665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MyAD_RS13670	COG0483	inositol monophosphate 1-phosphatase activity
MyAD_RS13680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MyAD_RS13695	COG1119	ATPase activity
MyAD_RS13705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MyAD_RS13715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MyAD_RS13725	COG0134	indole-3-glycerol-phosphate synthase activity
MyAD_RS13735	COG0159	tryptophan synthase activity
MyAD_RS13760	COG0243	molybdopterin cofactor binding
MyAD_RS13780	COG0129	dihydroxy-acid dehydratase activity
MyAD_RS13795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MyAD_RS13805	COG0167	dihydroorotate dehydrogenase activity
MyAD_RS13825	COG1968	undecaprenyl-diphosphatase activity
MyAD_RS13850	COG0215	cysteine-tRNA ligase activity
MyAD_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS13865	COG0646	methionine synthase
MyAD_RS13865	COG1410	methionine synthase
MyAD_RS13875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MyAD_RS13885	COG0477	Major facilitator Superfamily
MyAD_RS13890	COG0140	phosphoribosyl-ATP diphosphatase activity
MyAD_RS13895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MyAD_RS13905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MyAD_RS13935	COG0640	Transcriptional regulator
MyAD_RS13995	COG2205	protein histidine kinase activity
MyAD_RS14000	COG0745	RESPONSE REGULATOR receiver
MyAD_RS14005	COG0456	acetyltransferase
MyAD_RS14010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS14015	COG1917	Cupin 2, conserved barrel domain protein
MyAD_RS14020	COG5285	phytanoyl-CoA dioxygenase
MyAD_RS14025	COG4122	O-methyltransferase activity
MyAD_RS14035	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MyAD_RS14040	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MyAD_RS14045	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MyAD_RS14055	COG2378	regulation of single-species biofilm formation
MyAD_RS14060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MyAD_RS14095	COG0300	oxidoreductase activity
MyAD_RS14180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MyAD_RS14185	COG0463	Glycosyl transferase, family 2
MyAD_RS14205	COG2272	Belongs to the type-B carboxylesterase lipase family
MyAD_RS14220	COG1742	UPF0060 membrane protein
MyAD_RS14235	COG3265	gluconokinase activity
MyAD_RS14250	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MyAD_RS14250	COG0778	Nitroreductase
MyAD_RS14260	COG1177	transmembrane transport
MyAD_RS14265	COG1176	ABC-type spermidine putrescine transport system, permease component I
MyAD_RS14285	COG0596	Alpha beta hydrolase
MyAD_RS14305	COG2011	ABC-type metal ion transport system permease component
MyAD_RS14310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MyAD_RS14315	COG1464	Belongs to the NlpA lipoprotein family
MyAD_RS14320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS14375	COG2828	Protein conserved in bacteria
MyAD_RS14390	COG2828	Protein conserved in bacteria
MyAD_RS14395	COG3842	ATPase activity
MyAD_RS14410	COG2200	EAL domain
MyAD_RS14410	COG3287	FIST C domain
MyAD_RS14410	COG2199	diguanylate cyclase activity
MyAD_RS14415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MyAD_RS14420	COG1953	Uracil, thiamine, allantoin
MyAD_RS14430	COG3257	ureidoglycine aminohydrolase activity
MyAD_RS14440	COG1414	Transcriptional regulator
MyAD_RS14475	COG3002	Belongs to the UPF0753 family
MyAD_RS14480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MyAD_RS14515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MyAD_RS14525	COG0747	negative chemotaxis
MyAD_RS14530	COG0477	Major facilitator Superfamily
MyAD_RS14555	COG4221	oxidoreductase activity
MyAD_RS14560	COG1309	transcriptional regulator
MyAD_RS14580	COG2801	Transposase and inactivated derivatives
MyAD_RS14605	COG2337	Toxic component of a toxin-antitoxin (TA) module
MyAD_RS14615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MyAD_RS14660	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS14750	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS14760	COG0477	Major facilitator Superfamily
MyAD_RS14800	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MyAD_RS14810	COG3546	catalase activity
MyAD_RS14830	COG0545	Peptidyl-prolyl cis-trans isomerase
MyAD_RS14875	COG1278	Cold shock
MyAD_RS14900	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
MyAD_RS14910	COG2124	cytochrome p450
MyAD_RS14930	COG2755	lipolytic protein G-D-S-L family
MyAD_RS14950	COG2807	transmembrane transport
MyAD_RS14955	COG2186	Transcriptional regulator
MyAD_RS14965	COG3022	response to hydroperoxide
MyAD_RS15015	COG1546	Belongs to the CinA family
MyAD_RS15015	COG1058	Belongs to the CinA family
MyAD_RS15060	COG2070	2-Nitropropane dioxygenase
MyAD_RS15070	COG3383	formate dehydrogenase (NAD+) activity
MyAD_RS15095	COG0745	RESPONSE REGULATOR receiver
MyAD_RS15100	COG5002	protein histidine kinase activity
MyAD_RS15135	COG1376	ErfK ybiS ycfS ynhG family protein
MyAD_RS15145	COG3104	oligopeptide transport
MyAD_RS15185	COG0745	RESPONSE REGULATOR receiver
MyAD_RS15195	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS15245	COG1024	Enoyl-CoA hydratase
MyAD_RS15265	COG1802	Transcriptional regulator
MyAD_RS15275	COG1335	isochorismatase
MyAD_RS15315	COG1252	NADH dehydrogenase
MyAD_RS15325	COG0668	transmembrane transport
MyAD_RS15345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS15370	COG0039	L-malate dehydrogenase activity
MyAD_RS15385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS15420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS15425	COG1252	NADH dehydrogenase
MyAD_RS15435	COG0829	nickel cation binding
MyAD_RS15445	COG0830	nickel cation binding
MyAD_RS15460	COG0831	urea catabolic process
MyAD_RS15485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MyAD_RS15495	COG1253	flavin adenine dinucleotide binding
MyAD_RS15500	COG1253	flavin adenine dinucleotide binding
MyAD_RS15530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MyAD_RS15530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MyAD_RS15550	COG1716	ATPase activity
MyAD_RS15555	COG0509	glycine decarboxylation via glycine cleavage system
MyAD_RS15590	COG1053	succinate dehydrogenase
MyAD_RS15590	COG3976	FMN-binding domain protein
MyAD_RS15615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS15625	COG2272	Belongs to the type-B carboxylesterase lipase family
MyAD_RS15635	COG2076	Multidrug Resistance protein
MyAD_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS15710	COG2814	Major facilitator Superfamily
MyAD_RS15740	COG1937	Protein conserved in bacteria
MyAD_RS15760	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS15790	COG0659	secondary active sulfate transmembrane transporter activity
MyAD_RS15845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MyAD_RS15860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MyAD_RS15865	COG1122	ATPase activity
MyAD_RS15870	COG1268	BioY protein
MyAD_RS15880	COG2814	Major facilitator Superfamily
MyAD_RS15895	COG0667	Aldo Keto reductase
MyAD_RS15905	COG1914	H( )-stimulated, divalent metal cation uptake system
MyAD_RS15925	COG0596	Alpha beta hydrolase
MyAD_RS15945	COG0456	acetyltransferase
MyAD_RS15945	COG0454	-acetyltransferase
MyAD_RS15995	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MyAD_RS16015	COG1845	cytochrome c oxidase, subunit III
MyAD_RS16020	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS16025	COG1309	transcriptional regulator
MyAD_RS16030	COG0183	Belongs to the thiolase family
MyAD_RS16045	COG0427	acetyl-CoA hydrolase
MyAD_RS16060	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS16065	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS16090	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MyAD_RS16110	COG2301	Belongs to the HpcH HpaI aldolase family
MyAD_RS16115	COG1233	COG1233 Phytoene dehydrogenase and related
MyAD_RS16150	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS16160	COG0183	Belongs to the thiolase family
MyAD_RS16170	COG0183	Belongs to the thiolase family
MyAD_RS16185	COG4638	Rieske (2fe-2S)
MyAD_RS16190	COG1024	Enoyl-CoA hydratase
MyAD_RS16195	COG1024	Enoyl-CoA hydratase
MyAD_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS16220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS16245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS16250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS16260	COG2030	dehydratase
MyAD_RS16325	COG2329	Antibiotic biosynthesis monooxygenase
MyAD_RS16340	COG1176	ABC-type spermidine putrescine transport system, permease component I
MyAD_RS16345	COG1177	transmembrane transport
MyAD_RS16350	COG3842	ATPase activity
MyAD_RS16380	COG2223	nitrite transmembrane transporter activity
MyAD_RS16390	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS16395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MyAD_RS16400	COG0583	DNA-binding transcription factor activity
MyAD_RS16405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MyAD_RS16425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS16430	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS16445	COG0833	amino acid
MyAD_RS16450	COG3395	kinase activity
MyAD_RS16455	COG0235	Class ii aldolase
MyAD_RS16475	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MyAD_RS16480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS16485	COG0531	amino acid
MyAD_RS16500	COG2197	response regulator
MyAD_RS16510	COG2814	Major facilitator Superfamily
MyAD_RS16515	COG1846	Transcriptional regulator
MyAD_RS16525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS16530	COG1414	Transcriptional regulator
MyAD_RS16580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MyAD_RS16585	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MyAD_RS16590	COG3971	2-oxopent-4-enoate hydratase activity
MyAD_RS16605	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS16610	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS16615	COG3384	dioxygenase
MyAD_RS16635	COG1064	alcohol dehydrogenase
MyAD_RS16640	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS16645	COG0508	dehydrogenase complex catalyzes the overall conversion of
MyAD_RS16645	COG0596	Alpha beta hydrolase
MyAD_RS16660	COG2801	Transposase and inactivated derivatives
MyAD_RS16665	COG0582	viral genome integration into host DNA
MyAD_RS16675	COG3046	protein related to deoxyribodipyrimidine photolyase
MyAD_RS16680	COG0730	response to heat
MyAD_RS16690	COG1160	GTP binding
MyAD_RS16695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MyAD_RS16705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MyAD_RS16725	COG0494	nUDIX hydrolase
MyAD_RS16780	COG0647	UMP catabolic process
MyAD_RS16810	COG2094	Belongs to the DNA glycosylase MPG family
MyAD_RS16815	COG2835	tetraacyldisaccharide 4'-kinase activity
MyAD_RS16830	COG0488	(ABC) transporter
MyAD_RS16835	COG0165	Argininosuccinate lyase
MyAD_RS16840	COG0137	argininosuccinate synthase activity
MyAD_RS16850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MyAD_RS16855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MyAD_RS16860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MyAD_RS16865	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MyAD_RS16870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MyAD_RS16875	COG0072	phenylalanine-tRNA ligase activity
MyAD_RS16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MyAD_RS16880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MyAD_RS16895	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS16900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MyAD_RS16910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MyAD_RS16930	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MyAD_RS16965	COG1842	Phage shock protein A
MyAD_RS16975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MyAD_RS16990	COG3237	CsbD-like
MyAD_RS17030	COG0640	Transcriptional regulator
MyAD_RS17040	COG0798	PFAM Bile acid sodium symporter
MyAD_RS17090	COG0539	negative regulation of cytoplasmic translation
MyAD_RS17110	COG0583	DNA-binding transcription factor activity
MyAD_RS17135	COG1872	DUF167
MyAD_RS17175	COG2860	membrane
MyAD_RS17190	COG0783	Belongs to the Dps family
MyAD_RS17220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MyAD_RS17230	COG1271	oxidase subunit
MyAD_RS17235	COG1294	oxidase, subunit
MyAD_RS17240	COG4988	ABC transporter
MyAD_RS17245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MyAD_RS17255	COG1946	Acyl-CoA thioesterase
MyAD_RS17270	COG0070	glutamate synthase
MyAD_RS17270	COG0069	glutamate synthase activity
MyAD_RS17270	COG0067	glutamate synthase
MyAD_RS17285	COG0579	oxidoreductase
MyAD_RS17290	COG0583	DNA-binding transcription factor activity
MyAD_RS17315	COG0475	glutathione-regulated potassium exporter activity
MyAD_RS17325	COG1403	HNH endonuclease
MyAD_RS17330	COG0589	response to stress
MyAD_RS17350	COG3290	protein histidine kinase activity
MyAD_RS17360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MyAD_RS17360	COG0519	Catalyzes the synthesis of GMP from XMP
MyAD_RS17385	COG1799	cell septum assembly
MyAD_RS17405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MyAD_RS17415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MyAD_RS17435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MyAD_RS17440	COG0768	penicillin binding
MyAD_RS17450	COG0275	rRNA processing
MyAD_RS17475	COG0142	geranyltranstransferase activity
MyAD_RS17495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MyAD_RS17510	COG5650	phosphatidylinositol metabolic process
MyAD_RS17525	COG0003	Pfam Anion-transporting ATPase
MyAD_RS17540	COG1022	Amp-dependent synthetase and ligase
MyAD_RS17545	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS17570	COG1845	cytochrome c oxidase, subunit III
MyAD_RS17590	COG2318	DinB family
MyAD_RS17620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MyAD_RS17650	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MyAD_RS17655	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MyAD_RS17660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MyAD_RS17670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS17675	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MyAD_RS17710	COG0321	lipoyl(octanoyl) transferase activity
MyAD_RS17735	COG0174	glutamine synthetase
MyAD_RS17760	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MyAD_RS17765	COG0174	glutamine synthetase
MyAD_RS17790	COG1024	Enoyl-CoA hydratase
MyAD_RS17810	COG0492	ferredoxin-NADP+ reductase activity
MyAD_RS17915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MyAD_RS17925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MyAD_RS17930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MyAD_RS17955	COG0583	DNA-binding transcription factor activity
MyAD_RS18000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MyAD_RS18025	COG0028	Belongs to the TPP enzyme family
MyAD_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS18055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MyAD_RS18060	COG2252	PERMEase
MyAD_RS18070	COG1305	Transglutaminase-like
MyAD_RS18085	COG5001	Diguanylate cyclase
MyAD_RS18085	COG5002	protein histidine kinase activity
MyAD_RS18085	COG3447	MASE1 domain protein
MyAD_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS18105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MyAD_RS18105	COG2124	cytochrome p450
MyAD_RS18130	COG2963	transposase activity
MyAD_RS18135	COG2801	Transposase and inactivated derivatives
MyAD_RS18165	COG0765	amino acid transport
MyAD_RS18170	COG0765	amino acid transport
MyAD_RS18180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MyAD_RS18185	COG4948	Mandelate Racemase Muconate Lactonizing
MyAD_RS18190	COG0800	Aldolase
MyAD_RS18215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS18240	COG2814	Major facilitator Superfamily
MyAD_RS18280	COG0358	DNA primase activity
MyAD_RS18285	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MyAD_RS18310	COG0423	glycine-tRNA ligase activity
MyAD_RS18335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MyAD_RS18340	COG1381	Involved in DNA repair and RecF pathway recombination
MyAD_RS18370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MyAD_RS18385	COG0484	heat shock protein binding
MyAD_RS18390	COG1420	regulation of RNA biosynthetic process
MyAD_RS18420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS18445	COG1021	2,3-dihydroxybenzoate-AMP ligase
MyAD_RS18475	COG1309	transcriptional regulator
MyAD_RS18495	COG4208	sulfate ABC transporter
MyAD_RS18505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MyAD_RS18520	COG3387	PFAM Glycoside hydrolase 15-related
MyAD_RS18530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MyAD_RS18535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MyAD_RS18570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS18580	COG2011	ABC-type metal ion transport system permease component
MyAD_RS18595	COG1120	ATPase activity
MyAD_RS18600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS18620	COG0517	IMP dehydrogenase activity
MyAD_RS18620	COG0516	GMP reductase activity
MyAD_RS18625	COG1234	tRNA 3'-trailer cleavage
MyAD_RS18630	COG1305	Transglutaminase-like
MyAD_RS18660	COG1596	polysaccharide export
MyAD_RS18660	COG1555	photosystem II stabilization
MyAD_RS18665	COG0346	lactoylglutathione lyase activity
MyAD_RS18695	COG2755	lipolytic protein G-D-S-L family
MyAD_RS18700	COG0406	alpha-ribazole phosphatase activity
MyAD_RS18705	COG0799	negative regulation of ribosome biogenesis
MyAD_RS18720	COG0542	response to heat
MyAD_RS18725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MyAD_RS18730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MyAD_RS18765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MyAD_RS18770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MyAD_RS18775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MyAD_RS18780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MyAD_RS18785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MyAD_RS18790	COG1530	ribonuclease E activity
MyAD_RS18795	COG0105	UTP biosynthetic process
MyAD_RS18805	COG0285	dihydrofolate synthase activity
MyAD_RS18810	COG0525	valine-tRNA ligase activity
MyAD_RS18815	COG3268	Saccharopine dehydrogenase
MyAD_RS18820	COG1506	peptidase
MyAD_RS18820	COG0823	Involved in the tonB-independent uptake of proteins
MyAD_RS18825	COG0004	ammonium transporteR
MyAD_RS18855	COG1388	LysM domain
MyAD_RS18860	COG1388	LysM domain
MyAD_RS18865	COG0746	molybdenum cofactor guanylyltransferase activity
MyAD_RS18870	COG1013	pyruvate-flavodoxin oxidoreductase activity
MyAD_RS18875	COG0674	pyruvate-flavodoxin oxidoreductase activity
MyAD_RS18875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MyAD_RS18880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MyAD_RS18885	COG1609	Transcriptional regulator
MyAD_RS18890	COG0673	inositol 2-dehydrogenase activity
MyAD_RS18895	COG1082	Xylose isomerase domain protein TIM barrel
MyAD_RS18910	COG1172	Belongs to the binding-protein-dependent transport system permease family
MyAD_RS18920	COG2188	Transcriptional regulator
MyAD_RS18925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MyAD_RS18935	COG3718	enzyme involved in inositol metabolism
MyAD_RS18940	COG3962	Belongs to the TPP enzyme family
MyAD_RS18955	COG1403	HNH endonuclease
MyAD_RS18970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MyAD_RS18975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MyAD_RS18985	COG0740	serine-type endopeptidase activity
MyAD_RS18990	COG0740	serine-type endopeptidase activity
MyAD_RS18995	COG0544	peptidyl-prolyl cis-trans isomerase activity
MyAD_RS19030	COG4974	Belongs to the 'phage' integrase family
MyAD_RS19110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MyAD_RS19145	COG4221	oxidoreductase activity
MyAD_RS19165	COG2239	Acts as a magnesium transporter
MyAD_RS19170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MyAD_RS19185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MyAD_RS19205	COG0366	Alpha amylase catalytic
MyAD_RS19220	COG2902	Dehydrogenase
MyAD_RS19230	COG0629	single-stranded DNA binding
MyAD_RS19275	COG4251	negative regulation of phosphorylation
MyAD_RS19315	COG0508	dehydrogenase complex catalyzes the overall conversion of
MyAD_RS19340	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS19350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MyAD_RS19370	COG0300	oxidoreductase activity
MyAD_RS19375	COG0433	COG0433 Predicted ATPase
MyAD_RS19405	COG1376	ErfK ybiS ycfS ynhG family protein
MyAD_RS19415	COG1414	Transcriptional regulator
MyAD_RS19425	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS19465	COG3321	synthase
MyAD_RS19465	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MyAD_RS19465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MyAD_RS19485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MyAD_RS19490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MyAD_RS19505	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS19510	COG0183	Belongs to the thiolase family
MyAD_RS19515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS19605	COG0477	Major facilitator Superfamily
MyAD_RS19610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MyAD_RS19615	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MyAD_RS19645	COG3191	aminopeptidase activity
MyAD_RS19655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MyAD_RS19660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MyAD_RS19675	COG4257	antibiotic catabolic process
MyAD_RS19680	COG0058	SHG alpha-glucan phosphorylase activity
MyAD_RS19685	COG0366	Alpha amylase catalytic
MyAD_RS19690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MyAD_RS19700	COG2409	Drug exporters of the RND superfamily
MyAD_RS19705	COG0183	Belongs to the thiolase family
MyAD_RS19710	COG0346	lactoylglutathione lyase activity
MyAD_RS19720	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MyAD_RS19730	COG2066	Belongs to the glutaminase family
MyAD_RS19730	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MyAD_RS19745	COG0586	Pfam SNARE associated Golgi protein
MyAD_RS19755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MyAD_RS19775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MyAD_RS19790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MyAD_RS19795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MyAD_RS19800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MyAD_RS19805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MyAD_RS19810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MyAD_RS19810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MyAD_RS19815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MyAD_RS19820	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MyAD_RS19825	COG0356	it plays a direct role in the translocation of protons across the membrane
MyAD_RS19835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MyAD_RS19845	COG2890	protein-(glutamine-N5) methyltransferase activity
MyAD_RS19850	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MyAD_RS19860	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS19865	COG1309	transcriptional regulator
MyAD_RS19870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MyAD_RS19880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MyAD_RS19885	COG0460	homoserine dehydrogenase
MyAD_RS19890	COG0019	diaminopimelate decarboxylase activity
MyAD_RS19895	COG0018	arginyl-trna synthetase
MyAD_RS19905	COG1309	transcriptional regulator
MyAD_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS19935	COG2197	response regulator
MyAD_RS19955	COG0247	lactate metabolic process
MyAD_RS19955	COG0277	FAD linked oxidase domain protein
MyAD_RS19970	COG2318	DinB family
MyAD_RS19975	COG1218	3'(2'),5'-bisphosphate nucleotidase
MyAD_RS19985	COG0175	sulfate reduction
MyAD_RS19990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MyAD_RS20000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MyAD_RS20005	COG2205	protein histidine kinase activity
MyAD_RS20010	COG0745	RESPONSE REGULATOR receiver
MyAD_RS20135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS20155	COG0277	FAD linked oxidase domain protein
MyAD_RS20160	COG1132	(ABC) transporter
MyAD_RS20165	COG1132	(ABC) transporter
MyAD_RS20165	COG2375	cellular response to nickel ion
MyAD_RS20170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MyAD_RS20220	COG2814	Major facilitator Superfamily
MyAD_RS20230	COG0508	dehydrogenase complex catalyzes the overall conversion of
MyAD_RS20230	COG0567	Dehydrogenase, E1 component
MyAD_RS20255	COG0598	Magnesium transport protein CorA
MyAD_RS20305	COG2239	Acts as a magnesium transporter
MyAD_RS20330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MyAD_RS20335	COG5662	AntiSigma factor
MyAD_RS20340	COG1595	DNA-templated transcription, initiation
MyAD_RS20355	COG1309	transcriptional regulator
MyAD_RS20360	COG1131	(ABC) transporter
MyAD_RS20365	COG3559	Exporter of polyketide antibiotics
MyAD_RS20375	COG5001	Diguanylate cyclase
MyAD_RS20380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MyAD_RS20385	COG0297	glycogen (starch) synthase activity
MyAD_RS20390	COG0519	Catalyzes the synthesis of GMP from XMP
MyAD_RS20400	COG0463	Glycosyl transferase, family 2
MyAD_RS20410	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS20415	COG1611	Belongs to the LOG family
MyAD_RS20430	COG0488	(ABC) transporter
MyAD_RS20435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MyAD_RS20440	COG2171	N-acyltransferase activity
MyAD_RS20450	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS20465	COG0506	proline dehydrogenase activity
MyAD_RS20470	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS20490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MyAD_RS20500	COG1902	pentaerythritol trinitrate reductase activity
MyAD_RS20500	COG0446	pyridine nucleotide-disulphide oxidoreductase
MyAD_RS20505	COG2353	YceI-like domain
MyAD_RS20560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MyAD_RS20570	COG2376	Dihydroxyacetone kinase
MyAD_RS20575	COG0747	negative chemotaxis
MyAD_RS20585	COG1217	gtp-binding protein TYPA
MyAD_RS20605	COG1051	belongs to the nudix hydrolase family
MyAD_RS20640	COG3275	phosphorelay sensor kinase activity
MyAD_RS20645	COG3279	Response regulator of the LytR AlgR family
MyAD_RS20655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MyAD_RS20665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MyAD_RS20680	COG3467	pyridoxamine 5'-phosphate
MyAD_RS20695	COG2072	flavoprotein involved in K transport
MyAD_RS20710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MyAD_RS20725	COG2409	Drug exporters of the RND superfamily
MyAD_RS20740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS20745	COG1024	Enoyl-CoA hydratase
MyAD_RS20760	COG0702	epimerase
MyAD_RS20770	COG4977	sequence-specific DNA binding
MyAD_RS20775	COG2271	Major facilitator Superfamily
MyAD_RS20780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MyAD_RS20795	COG0183	Belongs to the thiolase family
MyAD_RS20800	COG2186	Transcriptional regulator
MyAD_RS20885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS20890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS20905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MyAD_RS20955	COG0012	GTP binding
MyAD_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS21040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MyAD_RS21050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MyAD_RS21060	COG0572	uridine kinase
MyAD_RS21075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MyAD_RS21085	COG3631	Ketosteroid isomerase-related protein
MyAD_RS21090	COG1331	Highly conserved protein containing a thioredoxin domain
MyAD_RS21100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MyAD_RS21110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MyAD_RS21125	COG5473	translation initiation factor activity
MyAD_RS21135	COG1714	RDD family
MyAD_RS21145	COG0657	acetylesterase activity
MyAD_RS21150	COG2755	lipolytic protein G-D-S-L family
MyAD_RS21155	COG0183	Belongs to the thiolase family
MyAD_RS21160	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MyAD_RS21175	COG1024	Enoyl-CoA hydratase
MyAD_RS21215	COG3804	dihydrodipicolinate reductase
MyAD_RS21235	COG0183	Belongs to the thiolase family
MyAD_RS21250	COG4565	transcriptional regulatory protein
MyAD_RS21255	COG3290	protein histidine kinase activity
MyAD_RS21260	COG1301	dicarboxylic acid transport
MyAD_RS21275	COG1126	abc transporter atp-binding protein
MyAD_RS21280	COG0765	amino acid transport
MyAD_RS21330	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS21350	COG1113	amino acid transport
MyAD_RS21360	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
MyAD_RS21450	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MyAD_RS21455	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MyAD_RS21490	COG3842	ATPase activity
MyAD_RS21505	COG2217	Heavy metal translocating P-type atpase
MyAD_RS21510	COG0640	Transcriptional regulator
MyAD_RS21550	COG2822	iron ion transport
MyAD_RS21575	COG2837	iron assimilation
MyAD_RS21590	COG0477	Major facilitator Superfamily
MyAD_RS21595	COG1309	transcriptional regulator
MyAD_RS21600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS21605	COG1024	Enoyl-CoA hydratase
MyAD_RS21610	COG1024	Enoyl-CoA hydratase
MyAD_RS21625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MyAD_RS21630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MyAD_RS21630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MyAD_RS21635	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS21645	COG3956	TIGRFAM MazG family protein
MyAD_RS21665	COG1309	transcriptional regulator
MyAD_RS21700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MyAD_RS21715	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS21720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MyAD_RS21730	COG3583	domain protein
MyAD_RS21735	COG0084	hydrolase, TatD family'
MyAD_RS21745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MyAD_RS21750	COG1522	sequence-specific DNA binding
MyAD_RS21755	COG0446	pyridine nucleotide-disulphide oxidoreductase
MyAD_RS21765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MyAD_RS21800	COG0415	Belongs to the DNA photolyase family
MyAD_RS21805	COG2235	arginine
MyAD_RS21835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MyAD_RS21840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MyAD_RS21840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MyAD_RS21855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MyAD_RS21870	COG5001	Diguanylate cyclase
MyAD_RS21890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MyAD_RS21925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MyAD_RS21930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MyAD_RS21960	COG0521	Mo-molybdopterin cofactor biosynthetic process
MyAD_RS21960	COG0315	cyclic pyranopterin monophosphate synthase activity
MyAD_RS21965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MyAD_RS21975	COG0745	RESPONSE REGULATOR receiver
MyAD_RS21995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MyAD_RS22010	COG1024	Enoyl-CoA hydratase
MyAD_RS22085	COG0045	succinate-CoA ligase (ADP-forming) activity
MyAD_RS22115	COG0166	Belongs to the GPI family
MyAD_RS22135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MyAD_RS22140	COG1289	transmembrane transporter activity
MyAD_RS22145	COG1950	PFAM Membrane protein of
MyAD_RS22175	COG2814	Major facilitator Superfamily
MyAD_RS22185	COG0142	geranyltranstransferase activity
MyAD_RS22200	COG2226	methyltransferase
MyAD_RS22215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MyAD_RS22220	COG3706	GGDEF domain
MyAD_RS22230	COG0328	RNA-DNA hybrid ribonuclease activity
MyAD_RS22240	COG1793	dna ligase
MyAD_RS22240	COG3285	dna ligase
MyAD_RS22245	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MyAD_RS22265	COG0531	amino acid
MyAD_RS22270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MyAD_RS22275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MyAD_RS22305	COG3415	Transposase
MyAD_RS22305	COG2801	Transposase and inactivated derivatives
MyAD_RS22345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS22350	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS22375	COG1017	nitric oxide dioxygenase activity
MyAD_RS22375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MyAD_RS22380	COG1335	isochorismatase
MyAD_RS22390	COG4251	negative regulation of phosphorylation
MyAD_RS22395	COG0784	Response regulator, receiver
MyAD_RS22410	COG0747	negative chemotaxis
MyAD_RS22420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MyAD_RS22425	COG4172	Belongs to the ABC transporter superfamily
MyAD_RS22435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MyAD_RS22440	COG1595	DNA-templated transcription, initiation
MyAD_RS22465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MyAD_RS22495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MyAD_RS22510	COG1024	Enoyl-CoA hydratase
MyAD_RS22520	COG2205	protein histidine kinase activity
MyAD_RS22525	COG0745	RESPONSE REGULATOR receiver
MyAD_RS22535	COG2259	Doxx family
MyAD_RS22555	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS22560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MyAD_RS22565	COG2197	response regulator
MyAD_RS22570	COG1132	(ABC) transporter
MyAD_RS22595	COG0545	Peptidyl-prolyl cis-trans isomerase
MyAD_RS22605	COG1846	Transcriptional regulator
MyAD_RS22620	COG1309	transcriptional regulator
MyAD_RS22625	COG1309	transcriptional regulator
MyAD_RS22680	COG1403	HNH endonuclease
MyAD_RS22695	COG1819	glycosyl
MyAD_RS22745	COG0435	Glutathione S-transferase
MyAD_RS22750	COG1278	Cold shock
MyAD_RS22780	COG0315	cyclic pyranopterin monophosphate synthase activity
MyAD_RS22780	COG0521	Mo-molybdopterin cofactor biosynthetic process
MyAD_RS22810	COG1846	Transcriptional regulator
MyAD_RS22825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS22840	COG4977	sequence-specific DNA binding
MyAD_RS22845	COG1250	3-hydroxyacyl-CoA dehydrogenase
MyAD_RS22845	COG1024	Enoyl-CoA hydratase
MyAD_RS22850	COG0183	Belongs to the thiolase family
MyAD_RS22855	COG1902	pentaerythritol trinitrate reductase activity
MyAD_RS22870	COG0831	urea catabolic process
MyAD_RS22870	COG0832	Belongs to the urease beta subunit family
MyAD_RS22875	COG0804	urea catabolic process
MyAD_RS22880	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MyAD_RS22885	COG0829	nickel cation binding
MyAD_RS22910	COG0531	amino acid
MyAD_RS22925	COG1953	Uracil, thiamine, allantoin
MyAD_RS22935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS22945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MyAD_RS22960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS22985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS22990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS23000	COG1233	COG1233 Phytoene dehydrogenase and related
MyAD_RS23050	COG2815	serine threonine protein kinase
MyAD_RS23050	COG0515	serine threonine protein kinase
MyAD_RS23090	COG1064	alcohol dehydrogenase
MyAD_RS23095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MyAD_RS23115	COG0456	acetyltransferase
MyAD_RS23120	COG0745	RESPONSE REGULATOR receiver
MyAD_RS23130	COG3118	belongs to the thioredoxin family
MyAD_RS23140	COG2897	thiosulfate sulfurtransferase activity
MyAD_RS23150	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MyAD_RS23160	COG0354	folic acid binding
MyAD_RS23170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MyAD_RS23205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MyAD_RS23220	COG1362	aminopeptidase activity
MyAD_RS23225	COG2837	iron assimilation
MyAD_RS23245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MyAD_RS23270	COG0386	Belongs to the glutathione peroxidase family
MyAD_RS23290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS23295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MyAD_RS23300	COG1120	ATPase activity
MyAD_RS23305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MyAD_RS23320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MyAD_RS23325	COG0531	amino acid
MyAD_RS23345	COG2124	cytochrome p450
MyAD_RS23375	COG1012	belongs to the aldehyde dehydrogenase family
MyAD_RS23390	COG4221	oxidoreductase activity
MyAD_RS23395	COG2124	cytochrome p450
MyAD_RS23425	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS23435	COG2205	protein histidine kinase activity
MyAD_RS23440	COG0745	RESPONSE REGULATOR receiver
MyAD_RS23480	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MyAD_RS23480	COG3608	succinylglutamate desuccinylase aspartoacylase
MyAD_RS23495	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MyAD_RS23515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS23530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MyAD_RS23560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS23565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MyAD_RS23590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS23595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MyAD_RS23600	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS23610	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS23615	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS23620	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS23640	COG1309	transcriptional regulator
MyAD_RS23645	COG2070	2-Nitropropane dioxygenase
MyAD_RS23655	COG1024	Enoyl-CoA hydratase
MyAD_RS23675	COG0477	Major facilitator Superfamily
MyAD_RS23685	COG0745	RESPONSE REGULATOR receiver
MyAD_RS23690	COG2124	cytochrome p450
MyAD_RS23695	COG4689	acetoacetate decarboxylase
MyAD_RS23700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MyAD_RS23715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MyAD_RS23730	COG4638	Rieske (2fe-2S)
MyAD_RS23760	COG0514	ATP-dependent DNA helicase (RecQ)
MyAD_RS23785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MyAD_RS23795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MyAD_RS23800	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MyAD_RS23810	COG1053	succinate dehydrogenase
MyAD_RS23815	COG2030	dehydratase
MyAD_RS23845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS23860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MyAD_RS23865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MyAD_RS23870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MyAD_RS23905	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS23910	COG2244	polysaccharide biosynthetic process
MyAD_RS23940	COG0438	transferase activity, transferring glycosyl groups
MyAD_RS23955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MyAD_RS23960	COG1231	oxidoreductase activity
MyAD_RS23970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MyAD_RS23975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MyAD_RS23980	COG2201	protein-glutamate methylesterase activity
MyAD_RS24015	COG2030	dehydratase
MyAD_RS24020	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24025	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24030	COG2124	cytochrome p450
MyAD_RS24035	COG0183	Belongs to the thiolase family
MyAD_RS24055	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS24065	COG1024	Enoyl-CoA hydratase
MyAD_RS24090	COG2233	PERMEase
MyAD_RS24105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MyAD_RS24110	COG0402	S-adenosylhomocysteine deaminase activity
MyAD_RS24130	COG1309	transcriptional regulator
MyAD_RS24140	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS24145	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24150	COG0318	PFAM AMP-dependent synthetase and ligase
MyAD_RS24155	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24160	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24165	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24175	COG0436	Aminotransferase
MyAD_RS24190	COG1070	Carbohydrate kinase
MyAD_RS24195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MyAD_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
MyAD_RS24210	COG0583	DNA-binding transcription factor activity
MyAD_RS24225	COG0346	lactoylglutathione lyase activity
MyAD_RS24240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MyAD_RS24250	COG1960	acyl-CoA dehydrogenase activity
MyAD_RS24255	COG1309	transcriptional regulator
MyAD_RS24270	COG1609	Transcriptional regulator
MyAD_RS24275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MyAD_RS24280	COG1121	(ABC) transporter
MyAD_RS24290	COG0523	cobalamin synthesis protein
MyAD_RS24300	COG0803	Belongs to the bacterial solute-binding protein 9 family
MyAD_RS24305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MyAD_RS24310	COG1121	(ABC) transporter
MyAD_RS24315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MyAD_RS24330	COG0701	Predicted permease
MyAD_RS24340	COG0640	Transcriptional regulator
MyAD_RS24350	COG0778	Nitroreductase
MyAD_RS24355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MyAD_RS24360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MyAD_RS24365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MyAD_RS24390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MyAD_RS24395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MyAD_RS24405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MyAD_RS24410	COG1329	Transcriptional regulator
MyAD_RS24420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MyAD_RS24425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MyAD_RS24435	COG0288	reversible hydration of carbon dioxide
MyAD_RS24440	COG1194	a g-specific adenine glycosylase
MyAD_RS24495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MyAD_RS24500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MyAD_RS24510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MyAD_RS24545	COG0302	gtp cyclohydrolase
MyAD_RS24550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MyAD_RS24555	COG2267	carboxylic ester hydrolase activity
MyAD_RS24565	COG1063	alcohol dehydrogenase
MyAD_RS24570	COG2968	Membrane
MyAD_RS24580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MyAD_RS24595	COG2027	D-alanyl-D-alanine carboxypeptidase
MyAD_RS24615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MyAD_RS24620	COG4948	Mandelate Racemase Muconate Lactonizing
MyAD_RS24625	COG1414	Transcriptional regulator
MyAD_RS24635	COG4608	Belongs to the ABC transporter superfamily
MyAD_RS24640	COG0444	Belongs to the ABC transporter superfamily
MyAD_RS24650	COG0601	transmembrane transport
MyAD_RS24655	COG0747	negative chemotaxis
MyAD_RS24660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MyAD_RS24665	COG0583	DNA-binding transcription factor activity
MyAD_RS24685	COG4948	Mandelate Racemase Muconate Lactonizing
MyAD_RS24690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MyAD_RS24750	COG0470	DNA polymerase III
MyAD_RS24760	COG1754	DNA topoisomerase type I activity
MyAD_RS24760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MyAD_RS24770	COG1278	Cold shock
MyAD_RS24775	COG1111	helicase
MyAD_RS24775	COG1205	dead DEAH box helicase
MyAD_RS24830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MyAD_RS24855	COG0494	nUDIX hydrolase
MyAD_RS24865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MyAD_RS24880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MyAD_RS24885	COG0251	oxidation-reduction process
MyAD_RS24915	COG1408	metallophosphoesterase
MyAD_RS24920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MyAD_RS24945	COG1946	Acyl-CoA thioesterase
MyAD_RS24970	COG0714	Associated with various cellular activities
MyAD_RS24990	COG1309	transcriptional regulator
MyAD_RS24995	COG0477	Major facilitator Superfamily
MyAD_RS25000	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
MyAD_RS25040	COG4585	Histidine kinase
MyAD_RS25045	COG1454	alcohol dehydrogenase
MyAD_RS25055	COG0542	response to heat
MyAD_RS25065	COG1403	HNH endonuclease
MyAD_RS25075	COG1733	regulation of RNA biosynthetic process
MyAD_RS25080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MyAD_RS25085	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
MyAD_RS25090	COG0121	glutamine amidotransferase
MyAD_RS25095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MyAD_RS25100	COG3572	ergothioneine biosynthetic process
MyAD_RS25150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MyAD_RS25155	COG2218	PFAM glutamate synthase alpha subunit domain protein
MyAD_RS25160	COG0069	glutamate synthase activity
MyAD_RS25165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MyAD_RS25210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MyAD_RS25215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MyAD_RS25220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MyAD_RS25230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MyAD_RS25235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MyAD_RS25240	COG0860	N-Acetylmuramoyl-L-alanine amidase
MyAD_RS25255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MyAD_RS25265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MyAD_RS25285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MyAD_RS25295	COG3285	dna ligase
MyAD_RS25295	COG1793	dna ligase
MyAD_RS25300	COG1793	dna ligase
MyAD_RS25305	COG1960	acyl-CoA dehydrogenase activity