locus-tag	class	description
FIV07_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIV07_RS00010	COG0592	DNA-directed DNA polymerase activity
FIV07_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FIV07_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIV07_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FIV07_RS00030	COG0187	DNA topoisomerase II activity
FIV07_RS00035	COG1372	Participates in initiation and elongation during chromosome replication
FIV07_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIV07_RS00055	COG4974	Belongs to the 'phage' integrase family
FIV07_RS00085	COG2255	four-way junction helicase activity
FIV07_RS00125	COG1760	l-serine dehydratase
FIV07_RS00170	COG0515	serine threonine protein kinase
FIV07_RS00170	COG2815	serine threonine protein kinase
FIV07_RS00175	COG0515	serine threonine protein kinase
FIV07_RS00180	COG0768	penicillin binding
FIV07_RS00195	COG1716	ATPase activity
FIV07_RS00200	COG1716	ATPase activity
FIV07_RS00240	COG2199	diguanylate cyclase activity
FIV07_RS00240	COG2200	EAL domain
FIV07_RS00250	COG2072	flavoprotein involved in K transport
FIV07_RS00275	COG1301	dicarboxylic acid transport
FIV07_RS00285	COG1115	amino acid carrier protein
FIV07_RS00310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV07_RS00325	COG2188	Transcriptional regulator
FIV07_RS00370	COG1673	EVE domain
FIV07_RS00380	COG1309	transcriptional regulator
FIV07_RS00445	COG2801	Transposase and inactivated derivatives
FIV07_RS00445	COG3415	Transposase
FIV07_RS00495	COG4842	Belongs to the WXG100 family
FIV07_RS00500	COG4842	Belongs to the WXG100 family
FIV07_RS00540	COG3415	Transposase
FIV07_RS00540	COG2801	Transposase and inactivated derivatives
FIV07_RS00570	COG1404	Belongs to the peptidase S8 family
FIV07_RS00580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV07_RS00585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV07_RS00585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIV07_RS00585	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIV07_RS00590	COG1105	Belongs to the carbohydrate kinase PfkB family
FIV07_RS00595	COG1349	DNA-binding transcription factor activity
FIV07_RS00600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIV07_RS00615	COG1233	COG1233 Phytoene dehydrogenase and related
FIV07_RS00630	COG1966	Carbon starvation protein
FIV07_RS00645	COG1741	Belongs to the pirin family
FIV07_RS00670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FIV07_RS00675	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS00685	COG3321	synthase
FIV07_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS00685	COG0604	alcohol dehydrogenase
FIV07_RS00705	COG2365	Tyrosine phosphatase family
FIV07_RS00740	COG4585	Histidine kinase
FIV07_RS00745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIV07_RS00770	COG1309	transcriptional regulator
FIV07_RS00775	COG1801	Protein of unknown function DUF72
FIV07_RS00785	COG1802	Transcriptional regulator
FIV07_RS00795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS00800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS00825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS00855	COG3001	Fructosamine kinase
FIV07_RS00890	COG2267	carboxylic ester hydrolase activity
FIV07_RS00910	COG4122	O-methyltransferase activity
FIV07_RS00925	COG1280	lysine exporter protein (LysE YggA)
FIV07_RS00940	COG1937	Protein conserved in bacteria
FIV07_RS00950	COG2801	Transposase and inactivated derivatives
FIV07_RS00960	COG1376	ErfK ybiS ycfS ynhG family protein
FIV07_RS00975	COG0714	Associated with various cellular activities
FIV07_RS00990	COG3590	peptidase
FIV07_RS01015	COG2409	Drug exporters of the RND superfamily
FIV07_RS01035	COG2205	protein histidine kinase activity
FIV07_RS01070	COG2409	Drug exporters of the RND superfamily
FIV07_RS01080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIV07_RS01095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FIV07_RS01100	COG3609	addiction module antidote protein, CC2985 family
FIV07_RS01105	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIV07_RS01115	COG1024	Enoyl-CoA hydratase
FIV07_RS01120	COG4221	oxidoreductase activity
FIV07_RS01130	COG2188	Transcriptional regulator
FIV07_RS01155	COG0657	acetylesterase activity
FIV07_RS01165	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS01170	COG0657	acetylesterase activity
FIV07_RS01180	COG0657	acetylesterase activity
FIV07_RS01185	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS01210	COG0500	methyltransferase
FIV07_RS01215	COG0297	glycogen (starch) synthase activity
FIV07_RS01255	COG4981	capsule polysaccharide biosynthetic process
FIV07_RS01265	COG1472	Belongs to the glycosyl hydrolase 3 family
FIV07_RS01275	COG2030	dehydratase
FIV07_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS01285	COG0183	Belongs to the thiolase family
FIV07_RS01290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS01295	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS01325	COG2409	Drug exporters of the RND superfamily
FIV07_RS01330	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS01335	COG5651	PPE family
FIV07_RS01375	COG1522	sequence-specific DNA binding
FIV07_RS01420	COG2146	nitrite reductase [NAD(P)H] activity
FIV07_RS01420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV07_RS01450	COG1984	allophanate hydrolase subunit 2
FIV07_RS01455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIV07_RS01475	COG1309	transcriptional regulator
FIV07_RS01550	COG1309	transcriptional regulator
FIV07_RS01645	COG1492	cobalamin metabolic process
FIV07_RS01665	COG0778	Nitroreductase
FIV07_RS01675	COG1309	transcriptional regulator
FIV07_RS01680	COG5001	Diguanylate cyclase
FIV07_RS01680	COG5002	protein histidine kinase activity
FIV07_RS01680	COG3447	MASE1 domain protein
FIV07_RS01690	COG2252	PERMEase
FIV07_RS01700	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS01705	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS01720	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS01730	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS01750	COG0346	lactoylglutathione lyase activity
FIV07_RS01765	COG0464	growth
FIV07_RS01770	COG3266	domain, Protein
FIV07_RS01775	COG1674	ftsk spoiiie
FIV07_RS01795	COG4842	Belongs to the WXG100 family
FIV07_RS01810	COG1404	Belongs to the peptidase S8 family
FIV07_RS01830	COG0702	epimerase
FIV07_RS01850	COG1597	lipid kinase activity
FIV07_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS01890	COG1174	glycine betaine transport
FIV07_RS01895	COG0517	IMP dehydrogenase activity
FIV07_RS01895	COG1125	glycine betaine transport
FIV07_RS01900	COG1174	glycine betaine transport
FIV07_RS01925	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV07_RS01940	COG3415	Transposase
FIV07_RS01940	COG2801	Transposase and inactivated derivatives
FIV07_RS01960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIV07_RS02045	COG0717	Belongs to the dCTP deaminase family
FIV07_RS02060	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIV07_RS02090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV07_RS02095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIV07_RS02100	COG2080	2 iron, 2 sulfur cluster binding
FIV07_RS02120	COG2181	nitrate reductase activity
FIV07_RS02120	COG0247	lactate metabolic process
FIV07_RS02130	COG0443	Heat shock 70 kDa protein
FIV07_RS02175	COG3387	PFAM Glycoside hydrolase 15-related
FIV07_RS02180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIV07_RS02195	COG1309	transcriptional regulator
FIV07_RS02200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS02220	COG0745	RESPONSE REGULATOR receiver
FIV07_RS02230	COG0443	Heat shock 70 kDa protein
FIV07_RS02235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIV07_RS02245	COG0789	Transcriptional regulator
FIV07_RS02275	COG0402	S-adenosylhomocysteine deaminase activity
FIV07_RS02290	COG1914	H( )-stimulated, divalent metal cation uptake system
FIV07_RS02295	COG4336	lyase activity
FIV07_RS02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV07_RS02315	COG1802	Transcriptional regulator
FIV07_RS02320	COG0277	FAD linked oxidase domain protein
FIV07_RS02335	COG0542	response to heat
FIV07_RS02375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIV07_RS02375	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV07_RS02420	COG1994	Peptidase M50
FIV07_RS02430	COG2132	Multicopper oxidase
FIV07_RS02435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIV07_RS02460	COG2124	cytochrome p450
FIV07_RS02465	COG2409	Drug exporters of the RND superfamily
FIV07_RS02500	COG4221	oxidoreductase activity
FIV07_RS02515	COG0640	Transcriptional regulator
FIV07_RS02540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS02555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIV07_RS02565	COG0515	serine threonine protein kinase
FIV07_RS02570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV07_RS02585	COG0352	thiamine-phosphate diphosphorylase activity
FIV07_RS02590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS02600	COG2022	thiamine diphosphate biosynthetic process
FIV07_RS02625	COG2234	aminopeptidase activity
FIV07_RS02630	COG2234	aminopeptidase activity
FIV07_RS02635	COG2233	PERMEase
FIV07_RS02675	COG2814	Major facilitator Superfamily
FIV07_RS02700	COG0242	peptide deformylase activity
FIV07_RS02720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV07_RS02735	COG1320	monovalent cation:proton antiporter activity
FIV07_RS02740	COG2212	antiporter activity
FIV07_RS02745	COG1863	multisubunit Na H antiporter MnhE subunit
FIV07_RS02750	COG0651	ATP synthesis coupled electron transport
FIV07_RS02755	COG1006	Multisubunit Na H antiporter MnhC subunit
FIV07_RS02760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIV07_RS02760	COG2111	Na H antiporter
FIV07_RS02770	COG3263	regulation of cellular component size
FIV07_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV07_RS02790	COG0688	phosphatidylethanolamine metabolic process
FIV07_RS02800	COG4221	oxidoreductase activity
FIV07_RS02815	COG0647	UMP catabolic process
FIV07_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS02850	COG0459	protein refolding
FIV07_RS02870	COG0300	oxidoreductase activity
FIV07_RS02875	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FIV07_RS02895	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS02905	COG2326	polyphosphate kinase activity
FIV07_RS02940	COG0586	Pfam SNARE associated Golgi protein
FIV07_RS02950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS02955	COG1024	Enoyl-CoA hydratase
FIV07_RS02985	COG1505	serine-type exopeptidase activity
FIV07_RS03000	COG1063	alcohol dehydrogenase
FIV07_RS03035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV07_RS03040	COG0444	Belongs to the ABC transporter superfamily
FIV07_RS03045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIV07_RS03105	COG2326	polyphosphate kinase activity
FIV07_RS03115	COG2733	membrane
FIV07_RS03155	COG0010	Belongs to the arginase family
FIV07_RS03175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIV07_RS03195	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS03210	COG5002	protein histidine kinase activity
FIV07_RS03215	COG0745	RESPONSE REGULATOR receiver
FIV07_RS03275	COG2030	dehydratase
FIV07_RS03290	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FIV07_RS03295	COG0181	hydroxymethylbilane synthase activity
FIV07_RS03300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV07_RS03375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIV07_RS03380	COG0406	alpha-ribazole phosphatase activity
FIV07_RS03390	COG0785	Cytochrome C biogenesis protein
FIV07_RS03400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIV07_RS03405	COG2894	cell division
FIV07_RS03450	COG0714	Associated with various cellular activities
FIV07_RS03465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIV07_RS03470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV07_RS03480	COG2070	2-Nitropropane dioxygenase
FIV07_RS03485	COG2205	protein histidine kinase activity
FIV07_RS03485	COG2202	Pas domain
FIV07_RS03490	COG0745	RESPONSE REGULATOR receiver
FIV07_RS03540	COG4221	oxidoreductase activity
FIV07_RS03545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIV07_RS03555	COG0546	phosphoglycolate phosphatase activity
FIV07_RS03580	COG4941	Belongs to the sigma-70 factor family
FIV07_RS03585	COG2807	transmembrane transport
FIV07_RS03590	COG2186	Transcriptional regulator
FIV07_RS03595	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS03610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS03660	COG1309	transcriptional regulator
FIV07_RS03690	COG4948	Mandelate Racemase Muconate Lactonizing
FIV07_RS03695	COG4977	sequence-specific DNA binding
FIV07_RS03710	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIV07_RS03725	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS03730	COG4221	oxidoreductase activity
FIV07_RS03735	COG2226	methyltransferase
FIV07_RS03750	COG0644	oxidoreductase
FIV07_RS03755	COG0142	geranyltranstransferase activity
FIV07_RS03760	COG0501	Belongs to the peptidase M48B family
FIV07_RS03790	COG1666	GTP binding
FIV07_RS03800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIV07_RS03815	COG2133	pyrroloquinoline quinone binding
FIV07_RS03825	COG1672	PFAM Archaeal ATPase
FIV07_RS03825	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FIV07_RS03880	COG2133	pyrroloquinoline quinone binding
FIV07_RS03890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV07_RS03890	COG4651	solute:proton antiporter activity
FIV07_RS03895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV07_RS03900	COG3391	amine dehydrogenase activity
FIV07_RS03900	COG5651	PPE family
FIV07_RS03915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV07_RS03920	COG4948	Mandelate Racemase Muconate Lactonizing
FIV07_RS03925	COG1414	Transcriptional regulator
FIV07_RS03935	COG4608	Belongs to the ABC transporter superfamily
FIV07_RS03940	COG0444	Belongs to the ABC transporter superfamily
FIV07_RS03945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV07_RS03950	COG0601	transmembrane transport
FIV07_RS03955	COG0747	negative chemotaxis
FIV07_RS03960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIV07_RS03965	COG3540	Alkaline phosphatase
FIV07_RS03970	COG0583	DNA-binding transcription factor activity
FIV07_RS03975	COG4948	Mandelate Racemase Muconate Lactonizing
FIV07_RS03980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV07_RS03990	COG1733	regulation of RNA biosynthetic process
FIV07_RS04015	COG2409	Drug exporters of the RND superfamily
FIV07_RS04030	COG1278	Cold shock
FIV07_RS04040	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS04130	COG1487	ribonuclease activity
FIV07_RS04195	COG0210	DNA helicase
FIV07_RS04215	COG3328	transposase activity
FIV07_RS04260	COG1484	DNA-dependent DNA replication
FIV07_RS04265	COG4584	PFAM Integrase catalytic
FIV07_RS04290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIV07_RS04305	COG2814	Major facilitator Superfamily
FIV07_RS04330	COG3654	unkown
FIV07_RS04335	COG0653	protein targeting
FIV07_RS04370	COG1073	alpha beta
FIV07_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS04380	COG1309	transcriptional regulator
FIV07_RS04405	COG1487	ribonuclease activity
FIV07_RS04425	COG3654	unkown
FIV07_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS04465	COG1309	transcriptional regulator
FIV07_RS04510	COG1309	transcriptional regulator
FIV07_RS04525	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS04540	COG0659	secondary active sulfate transmembrane transporter activity
FIV07_RS04545	COG0789	Transcriptional regulator
FIV07_RS04575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV07_RS04580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV07_RS04590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV07_RS04610	COG0531	amino acid
FIV07_RS04615	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIV07_RS04625	COG1309	transcriptional regulator
FIV07_RS04655	COG0058	SHG alpha-glucan phosphorylase activity
FIV07_RS04660	COG2203	Gaf domain
FIV07_RS04660	COG4251	negative regulation of phosphorylation
FIV07_RS04660	COG5001	Diguanylate cyclase
FIV07_RS04660	COG3706	GGDEF domain
FIV07_RS04665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV07_RS04670	COG1755	Isoprenylcysteine carboxyl methyltransferase
FIV07_RS04700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIV07_RS04725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIV07_RS04730	COG1074	ATP-dependent DNA helicase activity
FIV07_RS04735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIV07_RS04750	COG0598	Magnesium transport protein CorA
FIV07_RS04770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV07_RS04785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIV07_RS04790	COG2030	dehydratase
FIV07_RS04795	COG2030	dehydratase
FIV07_RS04810	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIV07_RS04820	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIV07_RS04825	COG0081	regulation of translation
FIV07_RS04835	COG4941	Belongs to the sigma-70 factor family
FIV07_RS04845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV07_RS04850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV07_RS04900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIV07_RS04925	COG0085	RNA polymerase activity
FIV07_RS04930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIV07_RS04935	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FIV07_RS04950	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS04965	COG1024	Enoyl-CoA hydratase
FIV07_RS04990	COG1309	transcriptional regulator
FIV07_RS04995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIV07_RS05010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIV07_RS05030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV07_RS05035	COG1834	amidinotransferase
FIV07_RS05040	COG1522	sequence-specific DNA binding
FIV07_RS05070	COG0535	radical SAM domain protein
FIV07_RS05105	COG0477	Major facilitator Superfamily
FIV07_RS05120	COG2272	Belongs to the type-B carboxylesterase lipase family
FIV07_RS05125	COG0051	transcription antitermination factor activity, RNA binding
FIV07_RS05130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIV07_RS05135	COG0088	Forms part of the polypeptide exit tunnel
FIV07_RS05140	COG0089	rRNA binding
FIV07_RS05150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIV07_RS05155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIV07_RS05160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIV07_RS05165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIV07_RS05170	COG0255	Belongs to the universal ribosomal protein uL29 family
FIV07_RS05175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIV07_RS05210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV07_RS05220	COG3619	membrane
FIV07_RS05225	COG3069	C4-dicarboxylate transmembrane transporter activity
FIV07_RS05230	COG2814	Major facilitator Superfamily
FIV07_RS05260	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS05265	COG2146	nitrite reductase [NAD(P)H] activity
FIV07_RS05270	COG0405	Gamma-glutamyltransferase
FIV07_RS05280	COG3069	C4-dicarboxylate transmembrane transporter activity
FIV07_RS05285	COG0154	amidase activity
FIV07_RS05295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIV07_RS05305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIV07_RS05310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIV07_RS05315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIV07_RS05320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIV07_RS05325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIV07_RS05330	COG1841	ribosomal large subunit assembly
FIV07_RS05345	COG0616	signal peptide processing
FIV07_RS05355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FIV07_RS05360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FIV07_RS05365	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FIV07_RS05375	COG0563	adenylate kinase activity
FIV07_RS05395	COG2197	response regulator
FIV07_RS05410	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS05420	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FIV07_RS05425	COG1088	dTDP-glucose 4,6-dehydratase activity
FIV07_RS05435	COG4191	Histidine kinase
FIV07_RS05485	COG1937	Protein conserved in bacteria
FIV07_RS05500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV07_RS05505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV07_RS05520	COG0450	alkyl hydroperoxide reductase
FIV07_RS05525	COG1253	flavin adenine dinucleotide binding
FIV07_RS05530	COG0561	phosphatase activity
FIV07_RS05540	COG4651	solute:proton antiporter activity
FIV07_RS05540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV07_RS05565	COG2239	Acts as a magnesium transporter
FIV07_RS05580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIV07_RS05585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIV07_RS05590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIV07_RS05595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIV07_RS05600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIV07_RS05610	COG0203	ribosomal protein L17
FIV07_RS05650	COG1404	Belongs to the peptidase S8 family
FIV07_RS05670	COG4842	Belongs to the WXG100 family
FIV07_RS05675	COG4842	Belongs to the WXG100 family
FIV07_RS05700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIV07_RS05710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIV07_RS05715	COG1648	precorrin-2 dehydrogenase activity
FIV07_RS05715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV07_RS05720	COG2197	response regulator
FIV07_RS05765	COG1280	lysine exporter protein (LysE YggA)
FIV07_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV07_RS05780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS05790	COG1396	sequence-specific DNA binding
FIV07_RS05800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV07_RS05805	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIV07_RS05815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIV07_RS05825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV07_RS05840	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS05860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS05870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIV07_RS05890	COG0076	glutamate decarboxylase activity
FIV07_RS05895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIV07_RS05910	COG0456	acetyltransferase
FIV07_RS05910	COG1214	PFAM Peptidase M22, glycoprotease
FIV07_RS05915	COG0456	acetyltransferase
FIV07_RS05920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIV07_RS05935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIV07_RS05940	COG0459	protein refolding
FIV07_RS05950	COG0604	alcohol dehydrogenase
FIV07_RS05995	COG0516	GMP reductase activity
FIV07_RS06015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIV07_RS06015	COG0519	Catalyzes the synthesis of GMP from XMP
FIV07_RS06025	COG2072	flavoprotein involved in K transport
FIV07_RS06040	COG0657	acetylesterase activity
FIV07_RS06060	COG4221	oxidoreductase activity
FIV07_RS06090	COG2030	dehydratase
FIV07_RS06100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS06105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS06130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS06150	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS06165	COG1024	Enoyl-CoA hydratase
FIV07_RS06170	COG1024	Enoyl-CoA hydratase
FIV07_RS06175	COG4638	Rieske (2fe-2S)
FIV07_RS06190	COG0183	Belongs to the thiolase family
FIV07_RS06200	COG0183	Belongs to the thiolase family
FIV07_RS06215	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS06220	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS06260	COG1233	COG1233 Phytoene dehydrogenase and related
FIV07_RS06270	COG1024	Enoyl-CoA hydratase
FIV07_RS06275	COG0596	Alpha beta hydrolase
FIV07_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS06320	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS06335	COG0427	acetyl-CoA hydrolase
FIV07_RS06345	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS06350	COG0183	Belongs to the thiolase family
FIV07_RS06355	COG1309	transcriptional regulator
FIV07_RS06360	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS06385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FIV07_RS06510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS06515	COG3328	transposase activity
FIV07_RS06540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV07_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS06560	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS06580	COG2124	cytochrome p450
FIV07_RS06625	COG1024	Enoyl-CoA hydratase
FIV07_RS06635	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS06655	COG3321	synthase
FIV07_RS06655	COG0604	alcohol dehydrogenase
FIV07_RS06685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV07_RS06770	COG3328	transposase activity
FIV07_RS06815	COG1716	ATPase activity
FIV07_RS06815	COG0842	Transport permease protein
FIV07_RS06815	COG1131	(ABC) transporter
FIV07_RS06825	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS06835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV07_RS06840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV07_RS06855	COG2124	cytochrome p450
FIV07_RS06875	COG0583	DNA-binding transcription factor activity
FIV07_RS06880	COG0183	Belongs to the thiolase family
FIV07_RS06885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV07_RS06925	COG3485	protocatechuate 3,4-dioxygenase
FIV07_RS06930	COG1414	Transcriptional regulator
FIV07_RS07000	COG2030	dehydratase
FIV07_RS07010	COG0587	DNA-directed DNA polymerase activity
FIV07_RS07025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIV07_RS07040	COG1953	Uracil, thiamine, allantoin
FIV07_RS07045	COG2205	protein histidine kinase activity
FIV07_RS07050	COG2018	Roadblock/LC7 domain
FIV07_RS07065	COG1357	PFAM Pentapeptide repeats (8 copies)
FIV07_RS07070	COG1959	2 iron, 2 sulfur cluster binding
FIV07_RS07075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV07_RS07075	COG1017	nitric oxide dioxygenase activity
FIV07_RS07085	COG0842	Transport permease protein
FIV07_RS07085	COG1716	ATPase activity
FIV07_RS07085	COG1131	(ABC) transporter
FIV07_RS07125	COG5285	phytanoyl-CoA dioxygenase
FIV07_RS07130	COG1917	Cupin 2, conserved barrel domain protein
FIV07_RS07135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS07175	COG1295	ribonuclease BN
FIV07_RS07180	COG1686	Belongs to the peptidase S11 family
FIV07_RS07185	COG1408	metallophosphoesterase
FIV07_RS07205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV07_RS07215	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS07230	COG1595	DNA-templated transcription, initiation
FIV07_RS07235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS07250	COG0142	geranyltranstransferase activity
FIV07_RS07275	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FIV07_RS07300	COG0789	Transcriptional regulator
FIV07_RS07305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIV07_RS07320	COG2009	succinate dehydrogenase
FIV07_RS07330	COG3415	Transposase
FIV07_RS07330	COG2801	Transposase and inactivated derivatives
FIV07_RS07345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIV07_RS07375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV07_RS07385	COG3180	Ammonia monooxygenase
FIV07_RS07400	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV07_RS07400	COG1473	amidohydrolase
FIV07_RS07410	COG0730	response to heat
FIV07_RS07425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS07430	COG2508	Transcriptional regulator
FIV07_RS07430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FIV07_RS07475	COG0564	pseudouridine synthase activity
FIV07_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS07495	COG1309	transcriptional regulator
FIV07_RS07520	COG5651	PPE family
FIV07_RS07520	COG3391	amine dehydrogenase activity
FIV07_RS07530	COG1201	RNA secondary structure unwinding
FIV07_RS07535	COG2909	trisaccharide binding
FIV07_RS07565	COG1309	transcriptional regulator
FIV07_RS07570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIV07_RS07570	COG2124	cytochrome p450
FIV07_RS07585	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS07590	COG1522	sequence-specific DNA binding
FIV07_RS07650	COG4770	biotin carboxylase activity
FIV07_RS07655	COG3706	GGDEF domain
FIV07_RS07680	COG3273	potassium ion transport
FIV07_RS07680	COG0471	metal ion transport
FIV07_RS07695	COG0659	secondary active sulfate transmembrane transporter activity
FIV07_RS07715	COG0477	Major facilitator Superfamily
FIV07_RS07720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS07740	COG2337	Toxic component of a toxin-antitoxin (TA) module
FIV07_RS07760	COG0277	FAD linked oxidase domain protein
FIV07_RS07760	COG0247	lactate metabolic process
FIV07_RS07780	COG0154	amidase activity
FIV07_RS07790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIV07_RS07790	COG2755	lipolytic protein G-D-S-L family
FIV07_RS07800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIV07_RS07810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV07_RS07835	COG0489	protein tyrosine kinase activity
FIV07_RS07840	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS07850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIV07_RS07860	COG2801	Transposase and inactivated derivatives
FIV07_RS07875	COG2244	polysaccharide biosynthetic process
FIV07_RS07885	COG1442	glycosyl transferase family 8
FIV07_RS07885	COG1216	Glycosyl transferase, family 2
FIV07_RS07890	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FIV07_RS07895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIV07_RS07905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV07_RS07955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIV07_RS07960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIV07_RS07965	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV07_RS08015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV07_RS08055	COG0657	acetylesterase activity
FIV07_RS08070	COG1316	TRANSCRIPTIONal
FIV07_RS08075	COG1091	dTDP-4-dehydrorhamnose reductase activity
FIV07_RS08100	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FIV07_RS08100	COG0778	Nitroreductase
FIV07_RS08125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIV07_RS08135	COG1482	cell wall glycoprotein biosynthetic process
FIV07_RS08145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS08150	COG0531	amino acid
FIV07_RS08160	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV07_RS08180	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIV07_RS08190	COG0657	acetylesterase activity
FIV07_RS08205	COG0745	RESPONSE REGULATOR receiver
FIV07_RS08210	COG5002	protein histidine kinase activity
FIV07_RS08215	COG5401	PFAM Sporulation and spore germination
FIV07_RS08220	COG0723	plastoquinol--plastocyanin reductase activity
FIV07_RS08220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS08235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIV07_RS08240	COG0653	protein targeting
FIV07_RS08255	COG2326	polyphosphate kinase activity
FIV07_RS08275	COG0656	L-ascorbic acid biosynthetic process
FIV07_RS08280	COG1162	GTPase activity
FIV07_RS08285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIV07_RS08290	COG2135	peptidase activity
FIV07_RS08300	COG2226	methyltransferase
FIV07_RS08310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIV07_RS08325	COG1595	DNA-templated transcription, initiation
FIV07_RS08330	COG5662	AntiSigma factor
FIV07_RS08340	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIV07_RS08355	COG1597	lipid kinase activity
FIV07_RS08385	COG0406	alpha-ribazole phosphatase activity
FIV07_RS08400	COG0513	Belongs to the DEAD box helicase family
FIV07_RS08445	COG0596	Alpha beta hydrolase
FIV07_RS08465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV07_RS08490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIV07_RS08505	COG3480	Lon protease (S16) C-terminal proteolytic domain
FIV07_RS08510	COG1615	UPF0182 protein
FIV07_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS08580	COG2720	vancomycin resistance protein
FIV07_RS08590	COG3290	protein histidine kinase activity
FIV07_RS08655	COG4251	negative regulation of phosphorylation
FIV07_RS08660	COG0640	Transcriptional regulator
FIV07_RS08670	COG2217	Heavy metal translocating P-type atpase
FIV07_RS08675	COG0640	Transcriptional regulator
FIV07_RS08685	COG0745	RESPONSE REGULATOR receiver
FIV07_RS08730	COG0247	lactate metabolic process
FIV07_RS08740	COG1556	Lactate utilization protein
FIV07_RS08745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIV07_RS08750	COG3383	formate dehydrogenase (NAD+) activity
FIV07_RS08755	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
FIV07_RS08760	COG3259	Nickel-dependent hydrogenase
FIV07_RS08770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIV07_RS08795	COG0469	pyruvate kinase activity
FIV07_RS08800	COG1063	alcohol dehydrogenase
FIV07_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS08870	COG2197	response regulator
FIV07_RS08875	COG0604	alcohol dehydrogenase
FIV07_RS08875	COG3321	synthase
FIV07_RS08890	COG2072	flavoprotein involved in K transport
FIV07_RS08925	COG1024	Enoyl-CoA hydratase
FIV07_RS08945	COG0713	ATP synthesis coupled electron transport
FIV07_RS08960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIV07_RS08965	COG1034	ATP synthesis coupled electron transport
FIV07_RS08980	COG0649	NAD binding
FIV07_RS08985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV07_RS08990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV07_RS09010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIV07_RS09035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV07_RS09040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS09060	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIV07_RS09075	COG0604	alcohol dehydrogenase
FIV07_RS09080	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09090	COG0483	inositol monophosphate 1-phosphatase activity
FIV07_RS09105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIV07_RS09110	COG0668	transmembrane transport
FIV07_RS09120	COG2884	Cell division ATP-binding protein ftsE
FIV07_RS09130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIV07_RS09140	COG5001	Diguanylate cyclase
FIV07_RS09155	COG4974	Belongs to the 'phage' integrase family
FIV07_RS09275	COG4584	PFAM Integrase catalytic
FIV07_RS09280	COG1484	DNA-dependent DNA replication
FIV07_RS09310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIV07_RS09380	COG0424	maF-like protein
FIV07_RS09395	COG3707	response regulator
FIV07_RS09410	COG1793	dna ligase
FIV07_RS09410	COG3285	dna ligase
FIV07_RS09415	COG2354	Protein conserved in bacteria
FIV07_RS09435	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS09450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIV07_RS09465	COG0477	Major facilitator Superfamily
FIV07_RS09475	COG1403	HNH endonuclease
FIV07_RS09480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIV07_RS09510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIV07_RS09520	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIV07_RS09530	COG0713	ATP synthesis coupled electron transport
FIV07_RS09535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIV07_RS09585	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09590	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09620	COG2072	flavoprotein involved in K transport
FIV07_RS09630	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09640	COG0183	Belongs to the thiolase family
FIV07_RS09645	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09650	COG1802	Transcriptional regulator
FIV07_RS09655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS09665	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS09670	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS09675	COG1024	Enoyl-CoA hydratase
FIV07_RS09680	COG1024	Enoyl-CoA hydratase
FIV07_RS09685	COG1024	Enoyl-CoA hydratase
FIV07_RS09695	COG1024	Enoyl-CoA hydratase
FIV07_RS09710	COG1024	Enoyl-CoA hydratase
FIV07_RS09715	COG0300	oxidoreductase activity
FIV07_RS09720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV07_RS09735	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS09750	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS09755	COG0183	Belongs to the thiolase family
FIV07_RS09770	COG0243	molybdopterin cofactor binding
FIV07_RS09775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS09785	COG2124	cytochrome p450
FIV07_RS09840	COG2072	flavoprotein involved in K transport
FIV07_RS09865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV07_RS09885	COG0477	Major facilitator Superfamily
FIV07_RS09890	COG1793	dna ligase
FIV07_RS09955	COG0431	NADPH-dependent FMN reductase
FIV07_RS09970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV07_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS10020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV07_RS10040	COG1404	Belongs to the peptidase S8 family
FIV07_RS10045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV07_RS10065	COG1132	(ABC) transporter
FIV07_RS10090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV07_RS10095	COG0644	oxidoreductase
FIV07_RS10100	COG1309	transcriptional regulator
FIV07_RS10120	COG1064	alcohol dehydrogenase
FIV07_RS10125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIV07_RS10135	COG0560	Phosphoserine phosphatase
FIV07_RS10135	COG3830	Belongs to the UPF0237 family
FIV07_RS10140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV07_RS10145	COG1119	ATPase activity
FIV07_RS10175	COG1115	amino acid carrier protein
FIV07_RS10180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIV07_RS10185	COG0110	maltose O-acetyltransferase activity
FIV07_RS10190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIV07_RS10205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIV07_RS10215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FIV07_RS10235	COG0482	sulfurtransferase activity
FIV07_RS10300	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS10310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIV07_RS10320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIV07_RS10325	COG0154	amidase activity
FIV07_RS10365	COG0440	acetolactate synthase activity
FIV07_RS10370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIV07_RS10380	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIV07_RS10395	COG0473	3-isopropylmalate dehydrogenase activity
FIV07_RS10405	COG2271	Major facilitator Superfamily
FIV07_RS10410	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV07_RS10415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV07_RS10435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIV07_RS10440	COG0066	3-isopropylmalate dehydratase activity
FIV07_RS10450	COG0494	nUDIX hydrolase
FIV07_RS10450	COG0406	alpha-ribazole phosphatase activity
FIV07_RS10455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIV07_RS10460	COG1920	GTP binding
FIV07_RS10465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIV07_RS10470	COG0626	cystathionine gamma-synthase activity
FIV07_RS10475	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIV07_RS10495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIV07_RS10510	COG1461	Dihydroxyacetone kinase
FIV07_RS10530	COG1122	ATPase activity
FIV07_RS10535	COG4721	ABC-type cobalt transport system, permease component
FIV07_RS10545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV07_RS10545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV07_RS10550	COG0730	response to heat
FIV07_RS10555	COG0656	L-ascorbic acid biosynthetic process
FIV07_RS10560	COG0657	acetylesterase activity
FIV07_RS10575	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIV07_RS10580	COG0742	ribosomal rna small subunit methyltransferase
FIV07_RS10585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIV07_RS10590	COG3599	regulation of cell shape
FIV07_RS10600	COG0571	ribonuclease III activity
FIV07_RS10605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV07_RS10615	COG1254	Belongs to the acylphosphatase family
FIV07_RS10645	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIV07_RS10660	COG1686	Belongs to the peptidase S11 family
FIV07_RS10665	COG1686	Belongs to the peptidase S11 family
FIV07_RS10675	COG2239	Acts as a magnesium transporter
FIV07_RS10680	COG0228	four-way junction DNA binding
FIV07_RS10690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIV07_RS10715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIV07_RS10730	COG0656	L-ascorbic acid biosynthetic process
FIV07_RS10735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS10750	COG0792	nuclease activity
FIV07_RS10775	COG4974	Belongs to the 'phage' integrase family
FIV07_RS10790	COG0052	Belongs to the universal ribosomal protein uS2 family
FIV07_RS10805	COG0154	amidase activity
FIV07_RS10820	COG1136	(ABC) transporter
FIV07_RS10835	COG0528	UMP kinase activity
FIV07_RS10840	COG0233	cytoplasmic translational termination
FIV07_RS10850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIV07_RS10890	COG3293	Transposase
FIV07_RS10950	COG0657	acetylesterase activity
FIV07_RS10960	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS10975	COG2130	NADP-dependent
FIV07_RS10980	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS11010	COG0415	Belongs to the DNA photolyase family
FIV07_RS11030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIV07_RS11035	COG0750	zinc metalloprotease
FIV07_RS11105	COG0367	asparagine synthase
FIV07_RS11115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIV07_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS11130	COG2186	Transcriptional regulator
FIV07_RS11150	COG0310	cobalt ion transport
FIV07_RS11165	COG1122	ATPase activity
FIV07_RS11170	COG2205	protein histidine kinase activity
FIV07_RS11175	COG0745	RESPONSE REGULATOR receiver
FIV07_RS11200	COG0579	oxidoreductase
FIV07_RS11225	COG1648	precorrin-2 dehydrogenase activity
FIV07_RS11225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIV07_RS11250	COG0779	Required for maturation of 30S ribosomal subunits
FIV07_RS11255	COG0195	Participates in both transcription termination and antitermination
FIV07_RS11265	COG0481	GTPase activity
FIV07_RS11275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIV07_RS11285	COG2226	methyltransferase
FIV07_RS11290	COG0789	Transcriptional regulator
FIV07_RS11290	COG4978	Transcriptional regulator
FIV07_RS11295	COG1116	anion transmembrane transporter activity
FIV07_RS11300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIV07_RS11305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV07_RS11315	COG0673	inositol 2-dehydrogenase activity
FIV07_RS11330	COG1024	Enoyl-CoA hydratase
FIV07_RS11355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIV07_RS11360	COG2977	Belongs to the P-Pant transferase superfamily
FIV07_RS11385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIV07_RS11395	COG1185	polyribonucleotide nucleotidyltransferase activity
FIV07_RS11410	COG3293	Transposase
FIV07_RS11425	COG3012	SEC-C Motif Domain Protein
FIV07_RS11430	COG0686	Belongs to the AlaDH PNT family
FIV07_RS11435	COG1522	sequence-specific DNA binding
FIV07_RS11445	COG0375	protein maturation
FIV07_RS11450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FIV07_RS11455	COG0298	carbon dioxide binding
FIV07_RS11460	COG0409	Hydrogenase expression formation protein
FIV07_RS11505	COG0316	Belongs to the HesB IscA family
FIV07_RS11505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIV07_RS11565	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIV07_RS11575	COG3214	Protein conserved in bacteria
FIV07_RS11580	COG0596	Alpha beta hydrolase
FIV07_RS11585	COG3706	GGDEF domain
FIV07_RS11600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIV07_RS11605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FIV07_RS11635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIV07_RS11645	COG1546	Belongs to the CinA family
FIV07_RS11645	COG1058	Belongs to the CinA family
FIV07_RS11650	COG1396	sequence-specific DNA binding
FIV07_RS11655	COG1842	Phage shock protein A
FIV07_RS11665	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
FIV07_RS11685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIV07_RS11685	COG1372	Participates in initiation and elongation during chromosome replication
FIV07_RS11690	COG2137	regulation of response to DNA damage stimulus
FIV07_RS11705	COG0765	amino acid transport
FIV07_RS11710	COG0765	amino acid transport
FIV07_RS11715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV07_RS11720	COG1126	abc transporter atp-binding protein
FIV07_RS11725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIV07_RS11735	COG1196	nuclear chromosome segregation
FIV07_RS11740	COG0697	spore germination
FIV07_RS11750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIV07_RS11755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIV07_RS11760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIV07_RS11765	COG0513	Belongs to the DEAD box helicase family
FIV07_RS11780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIV07_RS11785	COG1388	LysM domain
FIV07_RS11790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIV07_RS11875	COG0483	inositol monophosphate 1-phosphatase activity
FIV07_RS11895	COG0756	dUTP diphosphatase activity
FIV07_RS11925	COG0569	domain protein
FIV07_RS11930	COG0531	amino acid
FIV07_RS11935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIV07_RS11940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIV07_RS11945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIV07_RS11950	COG1802	Transcriptional regulator
FIV07_RS11990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIV07_RS12020	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS12030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIV07_RS12040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIV07_RS12050	COG3253	May function as heme-dependent peroxidase
FIV07_RS12060	COG3706	GGDEF domain
FIV07_RS12060	COG2203	Gaf domain
FIV07_RS12060	COG4251	negative regulation of phosphorylation
FIV07_RS12060	COG5001	Diguanylate cyclase
FIV07_RS12065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV07_RS12195	COG2801	Transposase and inactivated derivatives
FIV07_RS12195	COG3415	Transposase
FIV07_RS12265	COG0028	Belongs to the TPP enzyme family
FIV07_RS12270	COG0247	lactate metabolic process
FIV07_RS12270	COG0277	FAD linked oxidase domain protein
FIV07_RS12330	COG1609	Transcriptional regulator
FIV07_RS12335	COG0366	Alpha amylase catalytic
FIV07_RS12370	COG4762	Protein conserved in bacteria
FIV07_RS12385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIV07_RS12395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIV07_RS12400	COG1560	Kdo2-lipid A biosynthetic process
FIV07_RS12405	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS12415	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FIV07_RS12430	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS12435	COG1309	transcriptional regulator
FIV07_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS12455	COG0217	transcriptional regulatory protein
FIV07_RS12465	COG0632	four-way junction helicase activity
FIV07_RS12470	COG2255	four-way junction helicase activity
FIV07_RS12485	COG1022	Amp-dependent synthetase and ligase
FIV07_RS12485	COG3320	Male sterility
FIV07_RS12495	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS12515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIV07_RS12520	COG0747	negative chemotaxis
FIV07_RS12525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIV07_RS12530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIV07_RS12545	COG1126	abc transporter atp-binding protein
FIV07_RS12550	COG0765	amino acid transport
FIV07_RS12555	COG0765	amino acid transport
FIV07_RS12565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIV07_RS12575	COG0124	histidyl-tRNA synthetase
FIV07_RS12615	COG0683	leucine binding
FIV07_RS12625	COG3973	AAA domain
FIV07_RS12640	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS12650	COG1309	transcriptional regulator
FIV07_RS12670	COG2272	Belongs to the type-B carboxylesterase lipase family
FIV07_RS12680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIV07_RS12695	COG0183	Belongs to the thiolase family
FIV07_RS12700	COG1733	regulation of RNA biosynthetic process
FIV07_RS12705	COG0434	BtpA family
FIV07_RS12715	COG3842	ATPase activity
FIV07_RS12720	COG0395	ABC-type sugar transport system, permease component
FIV07_RS12740	COG1349	DNA-binding transcription factor activity
FIV07_RS12775	COG2261	transglycosylase associated protein
FIV07_RS12790	COG0038	chloride channel
FIV07_RS12795	COG0432	Pfam Uncharacterised protein family UPF0047
FIV07_RS12800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIV07_RS12805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIV07_RS12810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIV07_RS12815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV07_RS12820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FIV07_RS12825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIV07_RS12835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIV07_RS12845	COG0006	proline dipeptidase activity
FIV07_RS12850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIV07_RS12855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIV07_RS12875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FIV07_RS12880	COG0540	Belongs to the ATCase OTCase family
FIV07_RS12895	COG0505	Belongs to the CarA family
FIV07_RS12900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIV07_RS12905	COG0284	orotidine-5'-phosphate decarboxylase activity
FIV07_RS12920	COG1758	RNA polymerase activity
FIV07_RS12930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIV07_RS12940	COG2072	flavoprotein involved in K transport
FIV07_RS12950	COG0657	acetylesterase activity
FIV07_RS12970	COG1216	Glycosyl transferase, family 2
FIV07_RS13010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIV07_RS13020	COG1704	LemA family
FIV07_RS13025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIV07_RS13045	COG0477	Major facilitator Superfamily
FIV07_RS13060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV07_RS13060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIV07_RS13065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIV07_RS13075	COG0322	excinuclease ABC activity
FIV07_RS13080	COG1660	Displays ATPase and GTPase activities
FIV07_RS13090	COG1481	regulation of sporulation
FIV07_RS13100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIV07_RS13105	COG0126	phosphoglycerate kinase activity
FIV07_RS13110	COG0149	triose-phosphate isomerase activity
FIV07_RS13120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIV07_RS13150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIV07_RS13160	COG0109	protoheme IX farnesyltransferase activity
FIV07_RS13185	COG1131	(ABC) transporter
FIV07_RS13210	COG0396	ATPase activity
FIV07_RS13225	COG2151	metal-sulfur cluster biosynthetic enzyme
FIV07_RS13255	COG0129	dihydroxy-acid dehydratase activity
FIV07_RS13260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV07_RS13270	COG0488	(ABC) transporter
FIV07_RS13280	COG1309	transcriptional regulator
FIV07_RS13285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FIV07_RS13295	COG3883	PFAM NLP P60 protein
FIV07_RS13295	COG0791	NLP P60 protein
FIV07_RS13305	COG0714	Associated with various cellular activities
FIV07_RS13315	COG2304	oxidoreductase activity
FIV07_RS13325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIV07_RS13330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIV07_RS13375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIV07_RS13395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIV07_RS13400	COG2501	S4 domain
FIV07_RS13410	COG0252	asparaginase activity
FIV07_RS13415	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIV07_RS13480	COG0156	8-amino-7-oxononanoate synthase activity
FIV07_RS13485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIV07_RS13495	COG1309	transcriptional regulator
FIV07_RS13500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIV07_RS13525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIV07_RS13535	COG0157	Belongs to the NadC ModD family
FIV07_RS13545	COG1280	lysine exporter protein (LysE YggA)
FIV07_RS13560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV07_RS13565	COG0131	Imidazoleglycerol-phosphate dehydratase
FIV07_RS13575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIV07_RS13580	COG0483	inositol monophosphate 1-phosphatase activity
FIV07_RS13585	COG0107	imidazoleglycerol-phosphate synthase activity
FIV07_RS13590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIV07_RS13600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIV07_RS13610	COG0134	indole-3-glycerol-phosphate synthase activity
FIV07_RS13620	COG0159	tryptophan synthase activity
FIV07_RS13650	COG0070	glutamate synthase
FIV07_RS13650	COG0069	glutamate synthase activity
FIV07_RS13650	COG0067	glutamate synthase
FIV07_RS13665	COG1946	Acyl-CoA thioesterase
FIV07_RS13675	COG4988	ABC transporter
FIV07_RS13680	COG4988	ABC transporter
FIV07_RS13685	COG1294	oxidase, subunit
FIV07_RS13690	COG1271	oxidase subunit
FIV07_RS13700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIV07_RS13730	COG0783	Belongs to the Dps family
FIV07_RS13740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIV07_RS13780	COG1872	DUF167
FIV07_RS13805	COG2860	membrane
FIV07_RS13815	COG0539	negative regulation of cytoplasmic translation
FIV07_RS13820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIV07_RS13820	COG0237	dephospho-CoA kinase activity
FIV07_RS13830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV07_RS13855	COG2076	Multidrug Resistance protein
FIV07_RS13870	COG3588	fructose-bisphosphate aldolase
FIV07_RS13890	COG1842	Phage shock protein A
FIV07_RS13895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIV07_RS13895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FIV07_RS13905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIV07_RS13915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIV07_RS13935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIV07_RS13940	COG0072	phenylalanine-tRNA ligase activity
FIV07_RS13940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIV07_RS13945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIV07_RS13950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIV07_RS13955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIV07_RS13960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIV07_RS13965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIV07_RS13970	COG1438	arginine binding
FIV07_RS13975	COG0137	argininosuccinate synthase activity
FIV07_RS13980	COG0165	Argininosuccinate lyase
FIV07_RS13985	COG0488	(ABC) transporter
FIV07_RS14000	COG2835	tetraacyldisaccharide 4'-kinase activity
FIV07_RS14005	COG1309	transcriptional regulator
FIV07_RS14015	COG1131	(ABC) transporter
FIV07_RS14020	COG0657	acetylesterase activity
FIV07_RS14055	COG0647	UMP catabolic process
FIV07_RS14090	COG0504	CTP synthase activity
FIV07_RS14095	COG0494	nUDIX hydrolase
FIV07_RS14115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIV07_RS14120	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIV07_RS14130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIV07_RS14135	COG1160	GTP binding
FIV07_RS14150	COG0730	response to heat
FIV07_RS14155	COG3046	protein related to deoxyribodipyrimidine photolyase
FIV07_RS14165	COG0582	viral genome integration into host DNA
FIV07_RS14185	COG1484	DNA-dependent DNA replication
FIV07_RS14190	COG4584	PFAM Integrase catalytic
FIV07_RS14275	COG2161	toxin-antitoxin pair type II binding
FIV07_RS14290	COG3328	transposase activity
FIV07_RS14325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIV07_RS14405	COG1376	ErfK ybiS ycfS ynhG family protein
FIV07_RS14420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV07_RS14425	COG1121	(ABC) transporter
FIV07_RS14430	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIV07_RS14435	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS14455	COG2822	iron ion transport
FIV07_RS14465	COG0668	transmembrane transport
FIV07_RS14470	COG5002	protein histidine kinase activity
FIV07_RS14490	COG5002	protein histidine kinase activity
FIV07_RS14530	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIV07_RS14545	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS14570	COG4303	Ethanolamine ammonia lyase large subunit
FIV07_RS14590	COG2814	Major facilitator Superfamily
FIV07_RS14685	COG2272	Belongs to the type-B carboxylesterase lipase family
FIV07_RS14695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS14720	COG1053	succinate dehydrogenase
FIV07_RS14735	COG0653	protein targeting
FIV07_RS14760	COG0509	glycine decarboxylation via glycine cleavage system
FIV07_RS14765	COG1716	ATPase activity
FIV07_RS14785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV07_RS14785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIV07_RS14795	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS14800	COG3321	synthase
FIV07_RS14800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV07_RS14805	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS14845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV07_RS14875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS14885	COG3391	amine dehydrogenase activity
FIV07_RS14885	COG5651	PPE family
FIV07_RS14905	COG3391	amine dehydrogenase activity
FIV07_RS14905	COG5651	PPE family
FIV07_RS14915	COG2072	flavoprotein involved in K transport
FIV07_RS14925	COG4221	oxidoreductase activity
FIV07_RS14930	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIV07_RS14940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIV07_RS14950	COG1253	flavin adenine dinucleotide binding
FIV07_RS14955	COG1253	flavin adenine dinucleotide binding
FIV07_RS14960	COG1840	ABC-type Fe3 transport system, periplasmic component
FIV07_RS14965	COG1178	ABC-type Fe3 transport system permease component
FIV07_RS14970	COG3842	ATPase activity
FIV07_RS14980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIV07_RS15005	COG0831	urea catabolic process
FIV07_RS15010	COG0832	Belongs to the urease beta subunit family
FIV07_RS15015	COG0804	urea catabolic process
FIV07_RS15020	COG0830	nickel cation binding
FIV07_RS15035	COG1252	NADH dehydrogenase
FIV07_RS15040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS15065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FIV07_RS15070	COG0183	Belongs to the thiolase family
FIV07_RS15075	COG0039	L-malate dehydrogenase activity
FIV07_RS15100	COG4221	oxidoreductase activity
FIV07_RS15105	COG4221	oxidoreductase activity
FIV07_RS15115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIV07_RS15160	COG1335	isochorismatase
FIV07_RS15170	COG1802	Transcriptional regulator
FIV07_RS15195	COG1024	Enoyl-CoA hydratase
FIV07_RS15225	COG0174	glutamine synthetase
FIV07_RS15255	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS15310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIV07_RS15325	COG1376	ErfK ybiS ycfS ynhG family protein
FIV07_RS15345	COG1403	HNH endonuclease
FIV07_RS15370	COG2070	2-Nitropropane dioxygenase
FIV07_RS15400	COG1058	Belongs to the CinA family
FIV07_RS15400	COG1546	Belongs to the CinA family
FIV07_RS15440	COG3022	response to hydroperoxide
FIV07_RS15455	COG0784	Response regulator, receiver
FIV07_RS15460	COG4251	negative regulation of phosphorylation
FIV07_RS15470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIV07_RS15475	COG2755	lipolytic protein G-D-S-L family
FIV07_RS15480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIV07_RS15525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIV07_RS15540	COG0791	NLP P60 protein
FIV07_RS15540	COG3883	PFAM NLP P60 protein
FIV07_RS15545	COG5651	PPE family
FIV07_RS15545	COG3391	amine dehydrogenase activity
FIV07_RS15550	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS15560	COG3415	Transposase
FIV07_RS15560	COG2801	Transposase and inactivated derivatives
FIV07_RS15595	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS15600	COG2318	DinB family
FIV07_RS15610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIV07_RS15610	COG0116	Belongs to the methyltransferase superfamily
FIV07_RS15630	COG1252	NADH dehydrogenase
FIV07_RS15645	COG1363	Peptidase, m42
FIV07_RS15655	COG3265	gluconokinase activity
FIV07_RS15660	COG2610	gluconate transmembrane transporter activity
FIV07_RS15680	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV07_RS15690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIV07_RS15730	COG3119	arylsulfatase activity
FIV07_RS15785	COG1846	Transcriptional regulator
FIV07_RS15845	COG1309	transcriptional regulator
FIV07_RS15870	COG4651	solute:proton antiporter activity
FIV07_RS15870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIV07_RS15895	COG0243	molybdopterin cofactor binding
FIV07_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS15955	COG3842	ATPase activity
FIV07_RS15965	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIV07_RS15970	COG1177	transmembrane transport
FIV07_RS15985	COG1024	Enoyl-CoA hydratase
FIV07_RS16015	COG1742	UPF0060 membrane protein
FIV07_RS16020	COG2272	Belongs to the type-B carboxylesterase lipase family
FIV07_RS16040	COG0596	Alpha beta hydrolase
FIV07_RS16055	COG0463	Glycosyl transferase, family 2
FIV07_RS16060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIV07_RS16065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIV07_RS16165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV07_RS16170	COG2378	regulation of single-species biofilm formation
FIV07_RS16190	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FIV07_RS16205	COG1414	Transcriptional regulator
FIV07_RS16225	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FIV07_RS16230	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FIV07_RS16240	COG4122	O-methyltransferase activity
FIV07_RS16255	COG2197	response regulator
FIV07_RS16275	COG1222	aaa ATPase
FIV07_RS16310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIV07_RS16320	COG0640	Transcriptional regulator
FIV07_RS16330	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIV07_RS16335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIV07_RS16350	COG0140	phosphoribosyl-ATP diphosphatase activity
FIV07_RS16355	COG0477	Major facilitator Superfamily
FIV07_RS16360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIV07_RS16365	COG2233	PERMEase
FIV07_RS16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS16390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV07_RS16405	COG0646	methionine synthase
FIV07_RS16405	COG1410	methionine synthase
FIV07_RS16415	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIV07_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS16425	COG0215	cysteine-tRNA ligase activity
FIV07_RS16430	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIV07_RS16445	COG3415	Transposase
FIV07_RS16445	COG2801	Transposase and inactivated derivatives
FIV07_RS16455	COG1968	undecaprenyl-diphosphatase activity
FIV07_RS16475	COG0167	dihydroorotate dehydrogenase activity
FIV07_RS16485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV07_RS16495	COG0243	molybdopterin cofactor binding
FIV07_RS16500	COG2223	nitrite transmembrane transporter activity
FIV07_RS16510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIV07_RS16515	COG2146	nitrite reductase [NAD(P)H] activity
FIV07_RS16525	COG0589	response to stress
FIV07_RS16545	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FIV07_RS16585	COG1799	cell septum assembly
FIV07_RS16605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIV07_RS16615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIV07_RS16625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIV07_RS16630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV07_RS16645	COG0768	penicillin binding
FIV07_RS16655	COG0275	rRNA processing
FIV07_RS16660	COG2001	Belongs to the MraZ family
FIV07_RS16680	COG0142	geranyltranstransferase activity
FIV07_RS16700	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIV07_RS16715	COG5650	phosphatidylinositol metabolic process
FIV07_RS16730	COG0003	Pfam Anion-transporting ATPase
FIV07_RS16745	COG1022	Amp-dependent synthetase and ligase
FIV07_RS16750	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS16775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIV07_RS16780	COG1845	cytochrome c oxidase, subunit III
FIV07_RS16825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV07_RS16850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIV07_RS16855	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIV07_RS16860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS16865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIV07_RS16895	COG0321	lipoyl(octanoyl) transferase activity
FIV07_RS16900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIV07_RS16920	COG0174	glutamine synthetase
FIV07_RS16930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS16940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIV07_RS16945	COG0174	glutamine synthetase
FIV07_RS16975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIV07_RS16980	COG1024	Enoyl-CoA hydratase
FIV07_RS16985	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS17105	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIV07_RS17120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV07_RS17125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIV07_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS17180	COG0668	transmembrane transport
FIV07_RS17190	COG2197	response regulator
FIV07_RS17230	COG0747	negative chemotaxis
FIV07_RS17240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIV07_RS17245	COG4172	Belongs to the ABC transporter superfamily
FIV07_RS17285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FIV07_RS17295	COG3227	Zinc metalloprotease (Elastase)
FIV07_RS17315	COG3104	oligopeptide transport
FIV07_RS17325	COG0024	Methionine aminopeptidase
FIV07_RS17340	COG2199	diguanylate cyclase activity
FIV07_RS17340	COG2203	Gaf domain
FIV07_RS17400	COG2814	Major facilitator Superfamily
FIV07_RS17445	COG0358	DNA primase activity
FIV07_RS17450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIV07_RS17460	COG0423	glycine-tRNA ligase activity
FIV07_RS17480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIV07_RS17485	COG1381	Involved in DNA repair and RecF pathway recombination
FIV07_RS17515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIV07_RS17540	COG0484	heat shock protein binding
FIV07_RS17545	COG1420	regulation of RNA biosynthetic process
FIV07_RS17555	COG1073	alpha beta
FIV07_RS17580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV07_RS17605	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIV07_RS17665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIV07_RS17675	COG1937	Protein conserved in bacteria
FIV07_RS17690	COG3387	PFAM Glycoside hydrolase 15-related
FIV07_RS17710	COG0481	GTPase activity
FIV07_RS17725	COG0516	GMP reductase activity
FIV07_RS17725	COG0517	IMP dehydrogenase activity
FIV07_RS17730	COG1234	tRNA 3'-trailer cleavage
FIV07_RS17735	COG1305	Transglutaminase-like
FIV07_RS17745	COG2308	Evidence 4 Homologs of previously reported genes of
FIV07_RS17750	COG0268	Binds directly to 16S ribosomal RNA
FIV07_RS17765	COG1596	polysaccharide export
FIV07_RS17765	COG1555	photosystem II stabilization
FIV07_RS17775	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS17805	COG2755	lipolytic protein G-D-S-L family
FIV07_RS17810	COG0406	alpha-ribazole phosphatase activity
FIV07_RS17815	COG0799	negative regulation of ribosome biogenesis
FIV07_RS17820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIV07_RS17835	COG0542	response to heat
FIV07_RS17840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIV07_RS17845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV07_RS17875	COG3387	PFAM Glycoside hydrolase 15-related
FIV07_RS17880	COG1063	alcohol dehydrogenase
FIV07_RS17900	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIV07_RS17905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIV07_RS17910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIV07_RS17920	COG1530	ribonuclease E activity
FIV07_RS17920	COG1530	ribonuclease E activity
FIV07_RS17925	COG0105	UTP biosynthetic process
FIV07_RS17935	COG0285	dihydrofolate synthase activity
FIV07_RS17940	COG0525	valine-tRNA ligase activity
FIV07_RS17945	COG3268	Saccharopine dehydrogenase
FIV07_RS17950	COG0823	Involved in the tonB-independent uptake of proteins
FIV07_RS17950	COG1506	peptidase
FIV07_RS17955	COG0004	ammonium transporteR
FIV07_RS17970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV07_RS17990	COG1388	LysM domain
FIV07_RS17995	COG0746	molybdenum cofactor guanylyltransferase activity
FIV07_RS18000	COG1013	pyruvate-flavodoxin oxidoreductase activity
FIV07_RS18005	COG0674	pyruvate-flavodoxin oxidoreductase activity
FIV07_RS18005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FIV07_RS18010	COG0673	inositol 2-dehydrogenase activity
FIV07_RS18015	COG2197	response regulator
FIV07_RS18040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS18070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS18095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIV07_RS18100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIV07_RS18115	COG0740	serine-type endopeptidase activity
FIV07_RS18125	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIV07_RS18165	COG0723	plastoquinol--plastocyanin reductase activity
FIV07_RS18170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV07_RS18215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIV07_RS18235	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FIV07_RS18265	COG2902	Dehydrogenase
FIV07_RS18275	COG0629	single-stranded DNA binding
FIV07_RS18295	COG0204	Acyl-transferase
FIV07_RS18315	COG3549	Plasmid maintenance system killer
FIV07_RS18320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIV07_RS18325	COG0798	PFAM Bile acid sodium symporter
FIV07_RS18375	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS18380	COG3415	Transposase
FIV07_RS18380	COG2801	Transposase and inactivated derivatives
FIV07_RS18390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV07_RS18425	COG0300	oxidoreductase activity
FIV07_RS18430	COG0433	COG0433 Predicted ATPase
FIV07_RS18445	COG1376	ErfK ybiS ycfS ynhG family protein
FIV07_RS18455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV07_RS18480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV07_RS18490	COG0154	amidase activity
FIV07_RS18510	COG2271	Major facilitator Superfamily
FIV07_RS18520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIV07_RS18525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIV07_RS18525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIV07_RS18540	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS18555	COG1024	Enoyl-CoA hydratase
FIV07_RS18565	COG0183	Belongs to the thiolase family
FIV07_RS18600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS18625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS18630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS18640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS18665	COG2124	cytochrome p450
FIV07_RS18695	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS18730	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIV07_RS18750	COG2084	Dehydrogenase
FIV07_RS18760	COG2124	cytochrome p450
FIV07_RS18770	COG2124	cytochrome p450
FIV07_RS18780	COG1141	Ferredoxin
FIV07_RS18810	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS18830	COG1309	transcriptional regulator
FIV07_RS18835	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS18840	COG0183	Belongs to the thiolase family
FIV07_RS18845	COG1024	Enoyl-CoA hydratase
FIV07_RS18870	COG4638	Rieske (2fe-2S)
FIV07_RS18880	COG1228	amidohydrolase
FIV07_RS18890	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS18900	COG1024	Enoyl-CoA hydratase
FIV07_RS18910	COG2124	cytochrome p450
FIV07_RS18915	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS18925	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS18945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS18950	COG1024	Enoyl-CoA hydratase
FIV07_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS19015	COG1053	succinate dehydrogenase
FIV07_RS19020	COG3384	dioxygenase
FIV07_RS19025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS19030	COG2267	carboxylic ester hydrolase activity
FIV07_RS19040	COG1053	succinate dehydrogenase
FIV07_RS19065	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19070	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS19090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS19095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIV07_RS19100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIV07_RS19100	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIV07_RS19105	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS19135	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19145	COG1309	transcriptional regulator
FIV07_RS19155	COG3119	arylsulfatase activity
FIV07_RS19200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIV07_RS19205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIV07_RS19210	COG1234	tRNA 3'-trailer cleavage
FIV07_RS19215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIV07_RS19255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FIV07_RS19270	COG4257	antibiotic catabolic process
FIV07_RS19275	COG0058	SHG alpha-glucan phosphorylase activity
FIV07_RS19280	COG0366	Alpha amylase catalytic
FIV07_RS19295	COG2409	Drug exporters of the RND superfamily
FIV07_RS19300	COG0183	Belongs to the thiolase family
FIV07_RS19305	COG0346	lactoylglutathione lyase activity
FIV07_RS19315	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FIV07_RS19325	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19330	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS19340	COG0583	DNA-binding transcription factor activity
FIV07_RS19345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FIV07_RS19345	COG2066	Belongs to the glutaminase family
FIV07_RS19350	COG4221	oxidoreductase activity
FIV07_RS19360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIV07_RS19385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIV07_RS19400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIV07_RS19405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIV07_RS19410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIV07_RS19415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIV07_RS19425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIV07_RS19430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIV07_RS19435	COG0356	it plays a direct role in the translocation of protons across the membrane
FIV07_RS19445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIV07_RS19455	COG2890	protein-(glutamine-N5) methyltransferase activity
FIV07_RS19460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIV07_RS19465	COG0254	rRNA binding
FIV07_RS19470	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS19475	COG1309	transcriptional regulator
FIV07_RS19485	COG0083	homoserine kinase activity
FIV07_RS19490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIV07_RS19495	COG0460	homoserine dehydrogenase
FIV07_RS19500	COG0019	diaminopimelate decarboxylase activity
FIV07_RS19505	COG0018	arginyl-trna synthetase
FIV07_RS19560	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19565	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS19605	COG2197	response regulator
FIV07_RS19620	COG2070	2-Nitropropane dioxygenase
FIV07_RS19640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV07_RS19655	COG0175	sulfate reduction
FIV07_RS19660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIV07_RS19660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIV07_RS19670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIV07_RS19675	COG2205	protein histidine kinase activity
FIV07_RS19680	COG0745	RESPONSE REGULATOR receiver
FIV07_RS19750	COG0243	molybdopterin cofactor binding
FIV07_RS19755	COG0346	lactoylglutathione lyase activity
FIV07_RS19770	COG1490	D-aminoacyl-tRNA deacylase activity
FIV07_RS19805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS19830	COG0277	FAD linked oxidase domain protein
FIV07_RS19835	COG2080	2 iron, 2 sulfur cluster binding
FIV07_RS19840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIV07_RS19845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIV07_RS19860	COG2375	cellular response to nickel ion
FIV07_RS19860	COG1132	(ABC) transporter
FIV07_RS19895	COG2814	Major facilitator Superfamily
FIV07_RS19905	COG0567	Dehydrogenase, E1 component
FIV07_RS19905	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV07_RS19940	COG0598	Magnesium transport protein CorA
FIV07_RS19970	COG2301	Belongs to the HpcH HpaI aldolase family
FIV07_RS19975	COG2239	Acts as a magnesium transporter
FIV07_RS19995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIV07_RS20000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV07_RS20005	COG5662	AntiSigma factor
FIV07_RS20010	COG1595	DNA-templated transcription, initiation
FIV07_RS20015	COG4122	O-methyltransferase activity
FIV07_RS20025	COG1309	transcriptional regulator
FIV07_RS20030	COG1131	(ABC) transporter
FIV07_RS20035	COG3559	Exporter of polyketide antibiotics
FIV07_RS20045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIV07_RS20050	COG0297	glycogen (starch) synthase activity
FIV07_RS20060	COG0519	Catalyzes the synthesis of GMP from XMP
FIV07_RS20070	COG0463	Glycosyl transferase, family 2
FIV07_RS20080	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS20085	COG1611	Belongs to the LOG family
FIV07_RS20100	COG0488	(ABC) transporter
FIV07_RS20105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIV07_RS20120	COG0583	DNA-binding transcription factor activity
FIV07_RS20130	COG3706	GGDEF domain
FIV07_RS20150	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS20170	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS20180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIV07_RS20190	COG1902	pentaerythritol trinitrate reductase activity
FIV07_RS20190	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIV07_RS20195	COG2364	Membrane
FIV07_RS20200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV07_RS20205	COG2353	YceI-like domain
FIV07_RS20230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIV07_RS20255	COG0038	chloride channel
FIV07_RS20260	COG0747	negative chemotaxis
FIV07_RS20265	COG1217	gtp-binding protein TYPA
FIV07_RS20285	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIV07_RS20290	COG5001	Diguanylate cyclase
FIV07_RS20295	COG1051	belongs to the nudix hydrolase family
FIV07_RS20340	COG3275	phosphorelay sensor kinase activity
FIV07_RS20345	COG3279	Response regulator of the LytR AlgR family
FIV07_RS20355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV07_RS20365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIV07_RS20380	COG3467	pyridoxamine 5'-phosphate
FIV07_RS20400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIV07_RS20415	COG2409	Drug exporters of the RND superfamily
FIV07_RS20440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS20445	COG1024	Enoyl-CoA hydratase
FIV07_RS20460	COG3415	Transposase
FIV07_RS20460	COG2801	Transposase and inactivated derivatives
FIV07_RS20470	COG0702	epimerase
FIV07_RS20490	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS20495	COG1024	Enoyl-CoA hydratase
FIV07_RS20500	COG0183	Belongs to the thiolase family
FIV07_RS20505	COG0427	acetyl-CoA hydrolase
FIV07_RS20520	COG2186	Transcriptional regulator
FIV07_RS20575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS20600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS20605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS20630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS20675	COG2161	toxin-antitoxin pair type II binding
FIV07_RS20685	COG0012	GTP binding
FIV07_RS20700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIV07_RS20710	COG1570	exodeoxyribonuclease VII activity
FIV07_RS20725	COG3119	arylsulfatase activity
FIV07_RS20735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV07_RS20750	COG3119	arylsulfatase activity
FIV07_RS20765	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS20800	COG1914	H( )-stimulated, divalent metal cation uptake system
FIV07_RS20810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIV07_RS20825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIV07_RS20835	COG0572	uridine kinase
FIV07_RS20865	COG3631	Ketosteroid isomerase-related protein
FIV07_RS20870	COG1331	Highly conserved protein containing a thioredoxin domain
FIV07_RS20880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FIV07_RS20890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIV07_RS20910	COG5473	translation initiation factor activity
FIV07_RS20925	COG0657	acetylesterase activity
FIV07_RS20930	COG2755	lipolytic protein G-D-S-L family
FIV07_RS20935	COG0183	Belongs to the thiolase family
FIV07_RS21000	COG3804	dihydrodipicolinate reductase
FIV07_RS21010	COG0183	Belongs to the thiolase family
FIV07_RS21015	COG1301	dicarboxylic acid transport
FIV07_RS21020	COG3290	protein histidine kinase activity
FIV07_RS21025	COG4565	transcriptional regulatory protein
FIV07_RS21035	COG1366	Belongs to the anti-sigma-factor antagonist family
FIV07_RS21065	COG1846	Transcriptional regulator
FIV07_RS21070	COG1764	response to oxidative stress
FIV07_RS21080	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FIV07_RS21090	COG0038	chloride channel
FIV07_RS21105	COG3263	regulation of cellular component size
FIV07_RS21115	COG0530	calcium, potassium:sodium antiporter activity
FIV07_RS21200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FIV07_RS21225	COG1846	Transcriptional regulator
FIV07_RS21290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS21290	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIV07_RS21295	COG5651	PPE family
FIV07_RS21330	COG4974	Belongs to the 'phage' integrase family
FIV07_RS21350	COG4584	PFAM Integrase catalytic
FIV07_RS21355	COG1484	DNA-dependent DNA replication
FIV07_RS21390	COG0464	growth
FIV07_RS21405	COG2217	Heavy metal translocating P-type atpase
FIV07_RS21410	COG1937	Protein conserved in bacteria
FIV07_RS21450	COG0789	Transcriptional regulator
FIV07_RS21500	COG1376	ErfK ybiS ycfS ynhG family protein
FIV07_RS21520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV07_RS21550	COG0745	RESPONSE REGULATOR receiver
FIV07_RS21555	COG2205	protein histidine kinase activity
FIV07_RS21590	COG1196	nuclear chromosome segregation
FIV07_RS21665	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS21720	COG0569	domain protein
FIV07_RS21725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIV07_RS21760	COG0148	phosphopyruvate hydratase activity
FIV07_RS21770	COG3956	TIGRFAM MazG family protein
FIV07_RS21795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIV07_RS21810	COG1393	Belongs to the ArsC family
FIV07_RS21825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIV07_RS21840	COG0640	Transcriptional regulator
FIV07_RS21870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV07_RS21875	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS21880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIV07_RS21885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIV07_RS21890	COG3583	domain protein
FIV07_RS21895	COG0084	hydrolase, TatD family'
FIV07_RS21910	COG1595	DNA-templated transcription, initiation
FIV07_RS21930	COG2235	arginine
FIV07_RS21960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIV07_RS21965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIV07_RS21965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIV07_RS21980	COG0477	Major facilitator Superfamily
FIV07_RS21985	COG2272	Belongs to the type-B carboxylesterase lipase family
FIV07_RS22005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS22030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIV07_RS22035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIV07_RS22070	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIV07_RS22070	COG0315	cyclic pyranopterin monophosphate synthase activity
FIV07_RS22075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV07_RS22080	COG2205	protein histidine kinase activity
FIV07_RS22085	COG0745	RESPONSE REGULATOR receiver
FIV07_RS22110	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS22115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV07_RS22130	COG1024	Enoyl-CoA hydratase
FIV07_RS22145	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FIV07_RS22195	COG0739	heme binding
FIV07_RS22220	COG2755	lipolytic protein G-D-S-L family
FIV07_RS22220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIV07_RS22230	COG0166	Belongs to the GPI family
FIV07_RS22250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIV07_RS22255	COG1950	PFAM Membrane protein of
FIV07_RS22260	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS22280	COG2814	Major facilitator Superfamily
FIV07_RS22290	COG0328	RNA-DNA hybrid ribonuclease activity
FIV07_RS22305	COG1403	HNH endonuclease
FIV07_RS22320	COG3285	dna ligase
FIV07_RS22320	COG1793	dna ligase
FIV07_RS22325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIV07_RS22330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FIV07_RS22370	COG1595	DNA-templated transcription, initiation
FIV07_RS22375	COG5343	regulation of RNA biosynthetic process
FIV07_RS22380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIV07_RS22385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIV07_RS22395	COG1845	cytochrome c oxidase, subunit III
FIV07_RS22410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIV07_RS22485	COG0596	Alpha beta hydrolase
FIV07_RS22500	COG0183	Belongs to the thiolase family
FIV07_RS22505	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FIV07_RS22545	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FIV07_RS22570	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS22575	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS22580	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS22585	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS22595	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS22605	COG2072	flavoprotein involved in K transport
FIV07_RS22615	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS22630	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS22635	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS22640	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS22645	COG5001	Diguanylate cyclase
FIV07_RS22645	COG3300	MHYT domain
FIV07_RS22655	COG0243	molybdopterin cofactor binding
FIV07_RS22680	COG0714	Associated with various cellular activities
FIV07_RS22695	COG2124	cytochrome p450
FIV07_RS22700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIV07_RS22710	COG0702	epimerase
FIV07_RS22725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIV07_RS22740	COG1024	Enoyl-CoA hydratase
FIV07_RS22755	COG4133	protoheme IX ABC transporter activity
FIV07_RS22770	COG0596	Alpha beta hydrolase
FIV07_RS22775	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS22780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV07_RS22785	COG2197	response regulator
FIV07_RS22790	COG1132	(ABC) transporter
FIV07_RS22795	COG1132	(ABC) transporter
FIV07_RS22800	COG1132	(ABC) transporter
FIV07_RS22815	COG0545	Peptidyl-prolyl cis-trans isomerase
FIV07_RS22850	COG1309	transcriptional regulator
FIV07_RS22855	COG0259	pyridoxamine-phosphate oxidase activity
FIV07_RS22875	COG2723	6-phospho-beta-galactosidase activity
FIV07_RS22890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIV07_RS22905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV07_RS22925	COG2814	Major facilitator Superfamily
FIV07_RS22935	COG0435	Glutathione S-transferase
FIV07_RS22940	COG1278	Cold shock
FIV07_RS22970	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIV07_RS22990	COG1061	Type III restriction enzyme res subunit
FIV07_RS23000	COG2801	Transposase and inactivated derivatives
FIV07_RS23000	COG3415	Transposase
FIV07_RS23010	COG3328	transposase activity
FIV07_RS23015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS23030	COG1024	Enoyl-CoA hydratase
FIV07_RS23030	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV07_RS23035	COG0183	Belongs to the thiolase family
FIV07_RS23045	COG1902	pentaerythritol trinitrate reductase activity
FIV07_RS23060	COG0831	urea catabolic process
FIV07_RS23060	COG0832	Belongs to the urease beta subunit family
FIV07_RS23065	COG0804	urea catabolic process
FIV07_RS23070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIV07_RS23075	COG0829	nickel cation binding
FIV07_RS23080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIV07_RS23095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIV07_RS23125	COG2084	Dehydrogenase
FIV07_RS23130	COG1137	ATPase activity
FIV07_RS23135	COG0411	ABC transporter
FIV07_RS23150	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS23165	COG1609	Transcriptional regulator
FIV07_RS23180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIV07_RS23200	COG1233	COG1233 Phytoene dehydrogenase and related
FIV07_RS23215	COG1605	Chorismate mutase
FIV07_RS23245	COG0515	serine threonine protein kinase
FIV07_RS23275	COG1316	TRANSCRIPTIONal
FIV07_RS23285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIV07_RS23290	COG0581	inorganic phosphate transmembrane transporter activity
FIV07_RS23305	COG0456	acetyltransferase
FIV07_RS23310	COG0745	RESPONSE REGULATOR receiver
FIV07_RS23320	COG0492	ferredoxin-NADP+ reductase activity
FIV07_RS23320	COG3118	belongs to the thioredoxin family
FIV07_RS23325	COG2897	thiosulfate sulfurtransferase activity
FIV07_RS23345	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FIV07_RS23360	COG0354	folic acid binding
FIV07_RS23370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIV07_RS23380	COG0702	epimerase
FIV07_RS23385	COG2801	Transposase and inactivated derivatives
FIV07_RS23385	COG3415	Transposase
FIV07_RS23410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV07_RS23420	COG1362	aminopeptidase activity
FIV07_RS23425	COG2837	iron assimilation
FIV07_RS23440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIV07_RS23450	COG3573	Dehydrogenase
FIV07_RS23460	COG0386	Belongs to the glutathione peroxidase family
FIV07_RS23475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIV07_RS23495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIV07_RS23510	COG0531	amino acid
FIV07_RS23515	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS23535	COG2124	cytochrome p450
FIV07_RS23575	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS23590	COG0300	oxidoreductase activity
FIV07_RS23595	COG2124	cytochrome p450
FIV07_RS23620	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS23625	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS23640	COG2205	protein histidine kinase activity
FIV07_RS23645	COG0745	RESPONSE REGULATOR receiver
FIV07_RS23770	COG2084	Dehydrogenase
FIV07_RS23780	COG1024	Enoyl-CoA hydratase
FIV07_RS23790	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FIV07_RS23810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIV07_RS23835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS23840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIV07_RS23845	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS23855	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS23860	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS23865	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS23870	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS23875	COG1053	succinate dehydrogenase
FIV07_RS23890	COG0028	Belongs to the TPP enzyme family
FIV07_RS23895	COG1012	belongs to the aldehyde dehydrogenase family
FIV07_RS23900	COG2070	2-Nitropropane dioxygenase
FIV07_RS23910	COG1024	Enoyl-CoA hydratase
FIV07_RS23915	COG2124	cytochrome p450
FIV07_RS23925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS23935	COG0183	Belongs to the thiolase family
FIV07_RS23960	COG1309	transcriptional regulator
FIV07_RS23970	COG4638	Rieske (2fe-2S)
FIV07_RS23985	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24005	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24020	COG0514	ATP-dependent DNA helicase (RecQ)
FIV07_RS24040	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FIV07_RS24045	COG3971	2-oxopent-4-enoate hydratase activity
FIV07_RS24050	COG1053	succinate dehydrogenase
FIV07_RS24055	COG2030	dehydratase
FIV07_RS24090	COG2030	dehydratase
FIV07_RS24095	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24100	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24105	COG2124	cytochrome p450
FIV07_RS24110	COG0183	Belongs to the thiolase family
FIV07_RS24125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIV07_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24135	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24140	COG1024	Enoyl-CoA hydratase
FIV07_RS24175	COG0183	Belongs to the thiolase family
FIV07_RS24185	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24190	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24195	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS24200	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24210	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24215	COG0436	Aminotransferase
FIV07_RS24230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIV07_RS24235	COG3002	Belongs to the UPF0753 family
FIV07_RS24245	COG0288	reversible hydration of carbon dioxide
FIV07_RS24250	COG4214	carbohydrate transport
FIV07_RS24260	COG4213	ABC transporter substrate-binding protein
FIV07_RS24265	COG2115	Belongs to the xylose isomerase family
FIV07_RS24270	COG1940	carbohydrate kinase activity
FIV07_RS24275	COG1070	Carbohydrate kinase
FIV07_RS24280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV07_RS24285	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS24325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIV07_RS24335	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS24340	COG1309	transcriptional regulator
FIV07_RS24355	COG1609	Transcriptional regulator
FIV07_RS24365	COG1121	(ABC) transporter
FIV07_RS24370	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIV07_RS24375	COG0523	cobalamin synthesis protein
FIV07_RS24410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIV07_RS24415	COG1121	(ABC) transporter
FIV07_RS24420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIV07_RS24425	COG0640	Transcriptional regulator
FIV07_RS24445	COG0701	Predicted permease
FIV07_RS24465	COG0254	rRNA binding
FIV07_RS24475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIV07_RS24485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIV07_RS24490	COG0215	cysteine-tRNA ligase activity
FIV07_RS24495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIV07_RS24500	COG1329	Transcriptional regulator
FIV07_RS24505	COG2847	Copper chaperone PCu(A)C
FIV07_RS24510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIV07_RS24515	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FIV07_RS24530	COG1194	a g-specific adenine glycosylase
FIV07_RS24555	COG0596	Alpha beta hydrolase
FIV07_RS24570	COG0310	cobalt ion transport
FIV07_RS24575	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
FIV07_RS24585	COG1122	ATPase activity
FIV07_RS24590	COG0542	response to heat
FIV07_RS24600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIV07_RS24610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIV07_RS24615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FIV07_RS24620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIV07_RS24650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIV07_RS24655	COG0302	gtp cyclohydrolase
FIV07_RS24665	COG2267	carboxylic ester hydrolase activity
FIV07_RS24675	COG0243	molybdopterin cofactor binding
FIV07_RS24685	COG0037	tRNA processing
FIV07_RS24695	COG2027	D-alanyl-D-alanine carboxypeptidase
FIV07_RS24710	COG4266	Belongs to the allantoicase family
FIV07_RS24755	COG0470	DNA polymerase III
FIV07_RS24765	COG1754	DNA topoisomerase type I activity
FIV07_RS24765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIV07_RS24775	COG1278	Cold shock
FIV07_RS24780	COG1205	dead DEAH box helicase
FIV07_RS24780	COG1111	helicase
FIV07_RS24840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIV07_RS24865	COG0494	nUDIX hydrolase
FIV07_RS24875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIV07_RS24890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIV07_RS24920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIV07_RS24925	COG1408	metallophosphoesterase
FIV07_RS24930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIV07_RS24970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIV07_RS24990	COG0714	Associated with various cellular activities
FIV07_RS25025	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FIV07_RS25040	COG0667	Aldo Keto reductase
FIV07_RS25080	COG4585	Histidine kinase
FIV07_RS25085	COG1454	alcohol dehydrogenase
FIV07_RS25105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIV07_RS25110	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FIV07_RS25120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIV07_RS25125	COG3572	ergothioneine biosynthetic process
FIV07_RS25150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIV07_RS25155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIV07_RS25165	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS25210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIV07_RS25215	COG2218	PFAM glutamate synthase alpha subunit domain protein
FIV07_RS25220	COG0069	glutamate synthase activity
FIV07_RS25235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIV07_RS25255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIV07_RS25260	COG1492	cobalamin metabolic process
FIV07_RS25270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIV07_RS25275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIV07_RS25280	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIV07_RS25295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIV07_RS25310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV07_RS25330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIV07_RS25335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIV07_RS25355	COG1793	dna ligase
FIV07_RS25360	COG1793	dna ligase
FIV07_RS25365	COG3119	arylsulfatase activity
FIV07_RS25415	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIV07_RS25435	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FIV07_RS25445	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS25450	COG2188	Transcriptional regulator
FIV07_RS25455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIV07_RS25460	COG1231	oxidoreductase activity
FIV07_RS25465	COG2124	cytochrome p450
FIV07_RS25470	COG0343	queuine tRNA-ribosyltransferase activity
FIV07_RS25510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIV07_RS25510	COG2213	PTS system mannitol-specific
FIV07_RS25515	COG1063	alcohol dehydrogenase
FIV07_RS25530	COG0590	tRNA wobble adenosine to inosine editing
FIV07_RS25540	COG0287	Prephenate dehydrogenase
FIV07_RS25555	COG1174	glycine betaine transport
FIV07_RS25570	COG5416	Lipopolysaccharide assembly protein A domain
FIV07_RS25575	COG1305	Transglutaminase-like
FIV07_RS25595	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS25600	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIV07_RS25620	COG2318	DinB family
FIV07_RS25635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIV07_RS25655	COG0477	Major facilitator Superfamily
FIV07_RS25755	COG1216	Glycosyl transferase, family 2
FIV07_RS25770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIV07_RS25805	COG0277	FAD linked oxidase domain protein
FIV07_RS25810	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS25855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIV07_RS25860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIV07_RS25860	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FIV07_RS25860	COG3321	synthase
FIV07_RS25865	COG0318	PFAM AMP-dependent synthetase and ligase
FIV07_RS25870	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FIV07_RS25885	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIV07_RS25890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIV07_RS25895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIV07_RS25900	COG0671	phosphoesterase, PA-phosphatase related
FIV07_RS25905	COG1216	Glycosyl transferase, family 2
FIV07_RS25925	COG0561	phosphatase activity
FIV07_RS25935	COG0204	Acyl-transferase
FIV07_RS25940	COG2146	nitrite reductase [NAD(P)H] activity
FIV07_RS25940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIV07_RS25960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIV07_RS25985	COG0077	Prephenate dehydratase
FIV07_RS26005	COG1316	TRANSCRIPTIONal
FIV07_RS26010	COG1528	Iron-storage protein
FIV07_RS26045	COG2119	membrane
FIV07_RS26085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIV07_RS26090	COG2072	flavoprotein involved in K transport
FIV07_RS26100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIV07_RS26105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIV07_RS26105	COG1796	DNA polymerase
FIV07_RS26130	COG0067	glutamate synthase
FIV07_RS26130	COG0069	glutamate synthase activity
FIV07_RS26130	COG0070	glutamate synthase
FIV07_RS26140	COG0783	Belongs to the Dps family
FIV07_RS26155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIV07_RS26175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIV07_RS26205	COG2226	methyltransferase
FIV07_RS26210	COG0438	transferase activity, transferring glycosyl groups
FIV07_RS26215	COG3467	pyridoxamine 5'-phosphate
FIV07_RS26230	COG1960	acyl-CoA dehydrogenase activity
FIV07_RS26240	COG1335	isochorismatase
FIV07_RS26255	COG0366	Alpha amylase catalytic
FIV07_RS26270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIV07_RS26275	COG3842	ATPase activity
FIV07_RS26315	COG0477	Major facilitator Superfamily
FIV07_RS26355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIV07_RS26375	COG1063	alcohol dehydrogenase
FIV07_RS26380	COG1643	Atp-dependent helicase
FIV07_RS26395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIV07_RS26400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIV07_RS26470	COG0494	nUDIX hydrolase
FIV07_RS26480	COG0693	protein deglycase activity
FIV07_RS26495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIV07_RS26510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIV07_RS26515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIV07_RS26520	COG0824	Thioesterase
FIV07_RS26545	COG1301	dicarboxylic acid transport
FIV07_RS26560	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS26570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIV07_RS26605	COG1024	Enoyl-CoA hydratase
FIV07_RS26610	COG2208	phosphoserine phosphatase activity
FIV07_RS26610	COG2770	Histidine kinase
FIV07_RS26660	COG2124	cytochrome p450
FIV07_RS26660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIV07_RS26670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIV07_RS26695	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIV07_RS26715	COG1846	Transcriptional regulator
FIV07_RS26775	COG2030	dehydratase
FIV07_RS26780	COG1309	transcriptional regulator
FIV07_RS26840	COG0475	glutathione-regulated potassium exporter activity
FIV07_RS26860	COG3011	Protein conserved in bacteria
FIV07_RS26865	COG1252	NADH dehydrogenase
FIV07_RS26870	COG0471	metal ion transport
FIV07_RS26890	COG3629	intracellular signal transduction
FIV07_RS26890	COG3903	Transcriptional regulator
FIV07_RS26900	COG2149	membrane
FIV07_RS26910	COG1051	belongs to the nudix hydrolase family
FIV07_RS26925	COG0644	oxidoreductase
FIV07_RS26930	COG0531	amino acid
FIV07_RS26940	COG0149	triose-phosphate isomerase activity
FIV07_RS26945	COG0698	ribose 5-phosphate isomerase
FIV07_RS26950	COG2376	Dihydroxyacetone kinase
FIV07_RS26955	COG1802	Transcriptional regulator
FIV07_RS26965	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIV07_RS26970	COG2610	gluconate transmembrane transporter activity
FIV07_RS26975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS27000	COG3757	hydrolase, family 25
FIV07_RS27050	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIV07_RS27065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIV07_RS27075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIV07_RS27100	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FIV07_RS27100	COG1672	PFAM Archaeal ATPase
FIV07_RS27115	COG1595	DNA-templated transcription, initiation
FIV07_RS27125	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS27125	COG0604	alcohol dehydrogenase
FIV07_RS27125	COG3321	synthase
FIV07_RS27135	COG0346	lactoylglutathione lyase activity
FIV07_RS27160	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS27165	COG1595	DNA-templated transcription, initiation
FIV07_RS27170	COG2197	response regulator
FIV07_RS27215	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS27225	COG3852	Histidine kinase
FIV07_RS27230	COG2197	response regulator
FIV07_RS27235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIV07_RS27240	COG1309	transcriptional regulator
FIV07_RS27245	COG1028	Short-chain dehydrogenase reductase Sdr
FIV07_RS27270	COG0305	Participates in initiation and elongation during chromosome replication
FIV07_RS27275	COG0359	binds to the 23S rRNA
FIV07_RS27280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIV07_RS27290	COG0360	Binds together with S18 to 16S ribosomal RNA
FIV07_RS27300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIV07_RS27320	COG1260	myo-inositol-1-phosphate synthase
FIV07_RS27330	COG0596	Alpha beta hydrolase
FIV07_RS27330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIV07_RS27355	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FIV07_RS27360	COG4221	oxidoreductase activity
FIV07_RS27365	COG0495	leucyl-tRNA aminoacylation
FIV07_RS27380	COG1678	Uncharacterized ACR, COG1678
FIV07_RS27420	COG1595	DNA-templated transcription, initiation
FIV07_RS27440	COG3409	Peptidoglycan-binding domain 1 protein
FIV07_RS27440	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIV07_RS27455	COG1192	Involved in chromosome partitioning
FIV07_RS27460	COG0357	Ribosomal RNA small subunit methyltransferase G
FIV07_RS27470	COG0706	membrane insertase activity
FIV07_RS27475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIV07_RS27480	COG0594	ribonuclease P activity
FIV07_RS27525	COG1481	regulation of sporulation
FIV07_RS27655	COG3266	domain, Protein
FIV07_RS27665	COG1674	ftsk spoiiie
FIV07_RS27675	COG1192	Involved in chromosome partitioning
FIV07_RS27690	COG1404	Belongs to the peptidase S8 family
FIV07_RS27750	COG0464	growth
FIV07_RS27795	COG3177	Filamentation induced by cAMP protein fic
FIV07_RS27825	COG5651	PPE family
FIV07_RS27825	COG3391	amine dehydrogenase activity
FIV07_RS28075	COG0175	sulfate reduction
FIV07_RS28090	COG2267	carboxylic ester hydrolase activity
FIV07_RS28210	COG1404	Belongs to the peptidase S8 family
FIV07_RS28350	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIV07_RS28365	COG0303	'Molybdopterin
FIV07_RS28415	COG2252	PERMEase
FIV07_RS28420	COG1335	isochorismatase