locus-tag	class	description
C0085_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0085_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
C0085_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C0085_RS00090	COG0515	serine threonine protein kinase
C0085_RS00115	COG1716	ATPase activity
C0085_RS00190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0085_RS00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS00250	COG0596	Alpha beta hydrolase
C0085_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0085_RS00255	COG1260	myo-inositol-1-phosphate synthase
C0085_RS00275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0085_RS00345	COG0277	FAD linked oxidase domain protein
C0085_RS00375	COG1309	transcriptional regulator
C0085_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS00395	COG3344	reverse transcriptase
C0085_RS00410	COG1228	amidohydrolase
C0085_RS00430	COG1309	transcriptional regulator
C0085_RS00460	COG3260	NADH ubiquinone oxidoreductase 20
C0085_RS00470	COG0650	Formate hydrogenlyase subunit 4
C0085_RS00480	COG0651	ATP synthesis coupled electron transport
C0085_RS00485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C0085_RS00485	COG3261	NADH dehydrogenase
C0085_RS00530	COG1403	HNH endonuclease
C0085_RS00560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS00605	COG0657	acetylesterase activity
C0085_RS00615	COG2755	lipolytic protein G-D-S-L family
C0085_RS00615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0085_RS00645	COG1376	ErfK ybiS ycfS ynhG family protein
C0085_RS00650	COG0583	DNA-binding transcription factor activity
C0085_RS00655	COG0028	Belongs to the TPP enzyme family
C0085_RS00690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0085_RS00730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS00740	COG0596	Alpha beta hydrolase
C0085_RS00785	COG0038	chloride channel
C0085_RS00790	COG1309	transcriptional regulator
C0085_RS00805	COG1012	belongs to the aldehyde dehydrogenase family
C0085_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS00815	COG3321	synthase
C0085_RS00815	COG0604	alcohol dehydrogenase
C0085_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS00840	COG3391	amine dehydrogenase activity
C0085_RS00845	COG2365	Tyrosine phosphatase family
C0085_RS00880	COG1309	transcriptional regulator
C0085_RS00885	COG0657	acetylesterase activity
C0085_RS00885	COG5651	PPE family
C0085_RS00890	COG0657	acetylesterase activity
C0085_RS00890	COG5651	PPE family
C0085_RS00895	COG0277	FAD linked oxidase domain protein
C0085_RS00900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C0085_RS00920	COG1802	Transcriptional regulator
C0085_RS00930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0085_RS00935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0085_RS00960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0085_RS01010	COG2267	carboxylic ester hydrolase activity
C0085_RS01025	COG1472	Belongs to the glycosyl hydrolase 3 family
C0085_RS01050	COG1937	Protein conserved in bacteria
C0085_RS01055	COG2814	Major facilitator Superfamily
C0085_RS01060	COG1376	ErfK ybiS ycfS ynhG family protein
C0085_RS01070	COG1132	(ABC) transporter
C0085_RS01085	COG0243	molybdopterin cofactor binding
C0085_RS01090	COG3590	peptidase
C0085_RS01130	COG2409	Drug exporters of the RND superfamily
C0085_RS01185	COG0657	acetylesterase activity
C0085_RS01190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0085_RS01200	COG0657	acetylesterase activity
C0085_RS01210	COG1024	Enoyl-CoA hydratase
C0085_RS01220	COG0500	methyltransferase
C0085_RS01225	COG0297	glycogen (starch) synthase activity
C0085_RS01245	COG1487	ribonuclease activity
C0085_RS01285	COG4981	capsule polysaccharide biosynthetic process
C0085_RS01295	COG1472	Belongs to the glycosyl hydrolase 3 family
C0085_RS01315	COG2030	dehydratase
C0085_RS01325	COG0183	Belongs to the thiolase family
C0085_RS01330	COG1960	acyl-CoA dehydrogenase activity
C0085_RS01350	COG1053	succinate dehydrogenase
C0085_RS01370	COG2146	nitrite reductase [NAD(P)H] activity
C0085_RS01370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0085_RS01390	COG5651	PPE family
C0085_RS01430	COG1984	allophanate hydrolase subunit 2
C0085_RS01450	COG2223	nitrite transmembrane transporter activity
C0085_RS01455	COG2161	toxin-antitoxin pair type II binding
C0085_RS01465	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS01470	COG1960	acyl-CoA dehydrogenase activity
C0085_RS01485	COG0346	lactoylglutathione lyase activity
C0085_RS01530	COG5651	PPE family
C0085_RS01585	COG1404	Belongs to the peptidase S8 family
C0085_RS01610	COG1368	sulfuric ester hydrolase activity
C0085_RS01615	COG3391	amine dehydrogenase activity
C0085_RS01655	COG0778	Nitroreductase
C0085_RS01665	COG0671	phosphoesterase, PA-phosphatase related
C0085_RS01735	COG0717	Belongs to the dCTP deaminase family
C0085_RS01740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C0085_RS01745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0085_RS01760	COG2226	methyltransferase
C0085_RS01775	COG2226	methyltransferase
C0085_RS01785	COG1252	NADH dehydrogenase
C0085_RS01825	COG2181	nitrate reductase activity
C0085_RS01825	COG0247	lactate metabolic process
C0085_RS01900	COG0789	Transcriptional regulator
C0085_RS01910	COG5651	PPE family
C0085_RS01910	COG5263	repeat protein
C0085_RS01930	COG1994	Peptidase M50
C0085_RS01945	COG2239	Acts as a magnesium transporter
C0085_RS01990	COG0746	molybdenum cofactor guanylyltransferase activity
C0085_RS02030	COG3360	Dodecin
C0085_RS02075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0085_RS02090	COG1252	NADH dehydrogenase
C0085_RS02095	COG1403	HNH endonuclease
C0085_RS02140	COG1960	acyl-CoA dehydrogenase activity
C0085_RS02165	COG3321	synthase
C0085_RS02165	COG0604	alcohol dehydrogenase
C0085_RS02165	COG3321	synthase
C0085_RS02165	COG0604	alcohol dehydrogenase
C0085_RS02170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0085_RS02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0085_RS02235	COG2234	aminopeptidase activity
C0085_RS02270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0085_RS02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0085_RS02325	COG1183	phosphatidylcholine synthase activity
C0085_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS02365	COG5343	regulation of RNA biosynthetic process
C0085_RS02380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS02430	COG1024	Enoyl-CoA hydratase
C0085_RS02435	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS02445	COG1505	serine-type exopeptidase activity
C0085_RS02505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS02530	COG2733	membrane
C0085_RS02735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0085_RS02735	COG1648	precorrin-2 dehydrogenase activity
C0085_RS02760	COG1366	Belongs to the anti-sigma-factor antagonist family
C0085_RS02765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0085_RS02765	COG2755	lipolytic protein G-D-S-L family
C0085_RS02770	COG2755	lipolytic protein G-D-S-L family
C0085_RS02795	COG1113	amino acid transport
C0085_RS02810	COG0406	alpha-ribazole phosphatase activity
C0085_RS02820	COG0785	Cytochrome C biogenesis protein
C0085_RS02830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0085_RS02855	COG3391	amine dehydrogenase activity
C0085_RS02870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C0085_RS02875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0085_RS02920	COG0306	phosphate transporter
C0085_RS02930	COG4221	oxidoreductase activity
C0085_RS02950	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS02955	COG1228	amidohydrolase
C0085_RS03005	COG0142	geranyltranstransferase activity
C0085_RS03020	COG2072	flavoprotein involved in K transport
C0085_RS03035	COG2345	Transcriptional regulator
C0085_RS03050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0085_RS03125	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0085_RS03135	COG3537	Alpha-1,2-mannosidase
C0085_RS03155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0085_RS03180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0085_RS03190	COG1487	ribonuclease activity
C0085_RS03210	COG2002	toxin-antitoxin pair type II binding
C0085_RS03220	COG2972	Histidine kinase
C0085_RS03225	COG0745	RESPONSE REGULATOR receiver
C0085_RS03295	COG0653	protein targeting
C0085_RS03330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C0085_RS03370	COG1487	ribonuclease activity
C0085_RS03390	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C0085_RS03435	COG2030	dehydratase
C0085_RS03465	COG0081	regulation of translation
C0085_RS03470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS03475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS03480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS03485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS03525	COG1309	transcriptional regulator
C0085_RS03605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C0085_RS03630	COG1960	acyl-CoA dehydrogenase activity
C0085_RS03645	COG1024	Enoyl-CoA hydratase
C0085_RS03660	COG1510	regulation of RNA biosynthetic process
C0085_RS03675	COG1309	transcriptional regulator
C0085_RS03740	COG0535	radical SAM domain protein
C0085_RS03855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0085_RS03910	COG0200	Binds to the 23S rRNA
C0085_RS03915	COG0616	signal peptide processing
C0085_RS03930	COG0235	Class ii aldolase
C0085_RS03935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0085_RS04020	COG0657	acetylesterase activity
C0085_RS04095	COG0406	alpha-ribazole phosphatase activity
C0085_RS04120	COG0745	RESPONSE REGULATOR receiver
C0085_RS04125	COG2205	protein histidine kinase activity
C0085_RS04160	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS04220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0085_RS04250	COG0477	Major facilitator Superfamily
C0085_RS04260	COG3573	Dehydrogenase
C0085_RS04275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0085_RS04295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS04300	COG2188	Transcriptional regulator
C0085_RS04305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C0085_RS04310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0085_RS04320	COG3547	Transposase (IS116 IS110 IS902 family)
C0085_RS04330	COG2837	iron assimilation
C0085_RS04380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0085_RS04425	COG0745	RESPONSE REGULATOR receiver
C0085_RS04475	COG0640	Transcriptional regulator
C0085_RS04480	COG0590	tRNA wobble adenosine to inosine editing
C0085_RS04520	COG3391	amine dehydrogenase activity
C0085_RS04570	COG4106	trans-aconitate 2-methyltransferase activity
C0085_RS04575	COG0596	Alpha beta hydrolase
C0085_RS04595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0085_RS04605	COG4585	Histidine kinase
C0085_RS04610	COG2132	Multicopper oxidase
C0085_RS04620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0085_RS04660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0085_RS04680	COG0183	Belongs to the thiolase family
C0085_RS04685	COG1024	Enoyl-CoA hydratase
C0085_RS04685	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0085_RS04715	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0085_RS04740	COG3304	Inner membrane component domain
C0085_RS04745	COG1278	Cold shock
C0085_RS04980	COG0183	Belongs to the thiolase family
C0085_RS05020	COG3328	transposase activity
C0085_RS05070	COG0581	inorganic phosphate transmembrane transporter activity
C0085_RS05110	COG3285	dna ligase
C0085_RS05110	COG1793	dna ligase
C0085_RS05140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0085_RS05155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C0085_RS05180	COG0739	heme binding
C0085_RS05185	COG0045	succinate-CoA ligase (ADP-forming) activity
C0085_RS05295	COG1024	Enoyl-CoA hydratase
C0085_RS05310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0085_RS05335	COG3391	amine dehydrogenase activity
C0085_RS05350	COG3391	amine dehydrogenase activity
C0085_RS05360	COG0745	RESPONSE REGULATOR receiver
C0085_RS05365	COG2205	protein histidine kinase activity
C0085_RS05365	COG2972	Histidine kinase
C0085_RS05370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0085_RS05375	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0085_RS05375	COG0315	cyclic pyranopterin monophosphate synthase activity
C0085_RS05380	COG1970	mechanosensitive ion channel activity
C0085_RS05390	COG0577	efflux transmembrane transporter activity
C0085_RS05400	COG0142	geranyltranstransferase activity
C0085_RS05415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0085_RS05420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0085_RS05460	COG4106	trans-aconitate 2-methyltransferase activity
C0085_RS05465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0085_RS05465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0085_RS05500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0085_RS05515	COG0084	hydrolase, TatD family'
C0085_RS05545	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS05590	COG3956	TIGRFAM MazG family protein
C0085_RS05660	COG2205	protein histidine kinase activity
C0085_RS05665	COG0745	RESPONSE REGULATOR receiver
C0085_RS05690	COG0657	acetylesterase activity
C0085_RS05720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0085_RS05740	COG3328	transposase activity
C0085_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS05810	COG3391	amine dehydrogenase activity
C0085_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS05895	COG0183	Belongs to the thiolase family
C0085_RS05900	COG2755	lipolytic protein G-D-S-L family
C0085_RS05905	COG0657	acetylesterase activity
C0085_RS05945	COG1331	Highly conserved protein containing a thioredoxin domain
C0085_RS05975	COG0657	acetylesterase activity
C0085_RS06020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0085_RS06105	COG0012	GTP binding
C0085_RS06155	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C0085_RS06165	COG0596	Alpha beta hydrolase
C0085_RS06180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0085_RS06180	COG0574	Belongs to the PEP-utilizing enzyme family
C0085_RS06185	COG1403	HNH endonuclease
C0085_RS06190	COG3800	Transcriptional regulator
C0085_RS06190	COG1396	sequence-specific DNA binding
C0085_RS06195	COG2079	MmgE PrpD family protein
C0085_RS06225	COG0183	Belongs to the thiolase family
C0085_RS06245	COG1755	Isoprenylcysteine carboxyl methyltransferase
C0085_RS06260	COG1024	Enoyl-CoA hydratase
C0085_RS06265	COG1024	Enoyl-CoA hydratase
C0085_RS06270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0085_RS06290	COG2409	Drug exporters of the RND superfamily
C0085_RS06295	COG2409	Drug exporters of the RND superfamily
C0085_RS06340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0085_RS06350	COG3467	pyridoxamine 5'-phosphate
C0085_RS06400	COG1140	nitrate reductase beta subunit
C0085_RS06415	COG1217	gtp-binding protein TYPA
C0085_RS06465	COG1902	pentaerythritol trinitrate reductase activity
C0085_RS06465	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0085_RS06475	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C0085_RS06490	COG0604	alcohol dehydrogenase
C0085_RS06490	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS06490	COG3321	synthase
C0085_RS06505	COG5651	PPE family
C0085_RS06515	COG2508	Transcriptional regulator
C0085_RS06515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0085_RS06520	COG1012	belongs to the aldehyde dehydrogenase family
C0085_RS06525	COG0506	proline dehydrogenase activity
C0085_RS06535	COG0596	Alpha beta hydrolase
C0085_RS06550	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS06565	COG0657	acetylesterase activity
C0085_RS06570	COG5651	PPE family
C0085_RS06575	COG4842	Belongs to the WXG100 family
C0085_RS06585	COG3328	transposase activity
C0085_RS06595	COG0477	Major facilitator Superfamily
C0085_RS06620	COG1611	Belongs to the LOG family
C0085_RS06625	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS06645	COG0519	Catalyzes the synthesis of GMP from XMP
C0085_RS06680	COG3559	Exporter of polyketide antibiotics
C0085_RS06685	COG1131	(ABC) transporter
C0085_RS06690	COG1309	transcriptional regulator
C0085_RS06710	COG5662	AntiSigma factor
C0085_RS06715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0085_RS06720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0085_RS06765	COG2239	Acts as a magnesium transporter
C0085_RS06800	COG0598	Magnesium transport protein CorA
C0085_RS06840	COG2026	Addiction module toxin, RelE StbE family
C0085_RS06845	COG2161	toxin-antitoxin pair type II binding
C0085_RS06850	COG0567	Dehydrogenase, E1 component
C0085_RS06850	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0085_RS06895	COG0277	FAD linked oxidase domain protein
C0085_RS07275	COG0346	lactoylglutathione lyase activity
C0085_RS07295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0085_RS07305	COG0058	SHG alpha-glucan phosphorylase activity
C0085_RS07355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C0085_RS07570	COG2226	methyltransferase
C0085_RS07650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0085_RS07655	COG2072	flavoprotein involved in K transport
C0085_RS07660	COG2124	cytochrome p450
C0085_RS07690	COG0657	acetylesterase activity
C0085_RS07820	COG0657	acetylesterase activity
C0085_RS07825	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS07840	COG5651	PPE family
C0085_RS07840	COG3391	amine dehydrogenase activity
C0085_RS07855	COG1376	ErfK ybiS ycfS ynhG family protein
C0085_RS07885	COG0149	triose-phosphate isomerase activity
C0085_RS07910	COG0657	acetylesterase activity
C0085_RS07955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0085_RS07960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0085_RS07970	COG0657	acetylesterase activity
C0085_RS07980	COG0657	acetylesterase activity
C0085_RS08010	COG1131	(ABC) transporter
C0085_RS08035	COG0396	ATPase activity
C0085_RS08050	COG2151	metal-sulfur cluster biosynthetic enzyme
C0085_RS08055	COG1960	acyl-CoA dehydrogenase activity
C0085_RS08075	COG3118	belongs to the thioredoxin family
C0085_RS08085	COG0488	(ABC) transporter
C0085_RS08095	COG1309	transcriptional regulator
C0085_RS08100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0085_RS08110	COG0791	NLP P60 protein
C0085_RS08110	COG3883	PFAM NLP P60 protein
C0085_RS08120	COG0714	Associated with various cellular activities
C0085_RS08130	COG2304	oxidoreductase activity
C0085_RS08220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0085_RS08225	COG2226	methyltransferase
C0085_RS08230	COG3360	Dodecin
C0085_RS08250	COG1621	beta-fructofuranosidase activity
C0085_RS08265	COG4106	trans-aconitate 2-methyltransferase activity
C0085_RS08285	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C0085_RS08305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C0085_RS08310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0085_RS08390	COG3321	synthase
C0085_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS08390	COG0604	alcohol dehydrogenase
C0085_RS08420	COG2070	2-Nitropropane dioxygenase
C0085_RS08475	COG0300	oxidoreductase activity
C0085_RS08590	COG0791	NLP P60 protein
C0085_RS08590	COG3883	PFAM NLP P60 protein
C0085_RS08725	COG1073	alpha beta
C0085_RS08785	COG0483	inositol monophosphate 1-phosphatase activity
C0085_RS08790	COG0107	imidazoleglycerol-phosphate synthase activity
C0085_RS08800	COG0387	Pfam Sodium calcium exchanger
C0085_RS08860	COG1946	Acyl-CoA thioesterase
C0085_RS08865	COG0456	acetyltransferase
C0085_RS08865	COG0454	-acetyltransferase
C0085_RS08870	COG1132	(ABC) transporter
C0085_RS08875	COG4988	ABC transporter
C0085_RS08880	COG1294	oxidase, subunit
C0085_RS08885	COG1271	oxidase subunit
C0085_RS08975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0085_RS09025	COG0657	acetylesterase activity
C0085_RS09040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0085_RS09050	COG3391	amine dehydrogenase activity
C0085_RS09100	COG0604	alcohol dehydrogenase
C0085_RS09100	COG3321	synthase
C0085_RS09105	COG3321	synthase
C0085_RS09105	COG0604	alcohol dehydrogenase
C0085_RS09110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS09110	COG3321	synthase
C0085_RS09110	COG0604	alcohol dehydrogenase
C0085_RS09110	COG4221	oxidoreductase activity
C0085_RS09115	COG3321	synthase
C0085_RS09115	COG0604	alcohol dehydrogenase
C0085_RS09115	COG3321	synthase
C0085_RS09115	COG0604	alcohol dehydrogenase
C0085_RS09130	COG0488	(ABC) transporter
C0085_RS09185	COG1960	acyl-CoA dehydrogenase activity
C0085_RS09190	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C0085_RS09210	COG2835	tetraacyldisaccharide 4'-kinase activity
C0085_RS09250	COG0647	UMP catabolic process
C0085_RS09290	COG0494	nUDIX hydrolase
C0085_RS09305	COG4122	O-methyltransferase activity
C0085_RS09310	COG1113	amino acid transport
C0085_RS09315	COG5651	PPE family
C0085_RS09330	COG0659	secondary active sulfate transmembrane transporter activity
C0085_RS09340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0085_RS09345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0085_RS09385	COG3246	L-lysine catabolic process to acetate
C0085_RS09535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C0085_RS09545	COG1131	(ABC) transporter
C0085_RS09545	COG0842	Transport permease protein
C0085_RS09545	COG1716	ATPase activity
C0085_RS09560	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS09575	COG5651	PPE family
C0085_RS09575	COG5263	repeat protein
C0085_RS09605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS09645	COG1937	Protein conserved in bacteria
C0085_RS09745	COG5651	PPE family
C0085_RS09755	COG5651	PPE family
C0085_RS09765	COG5651	PPE family
C0085_RS09795	COG1404	Belongs to the peptidase S8 family
C0085_RS09815	COG5651	PPE family
C0085_RS09835	COG0657	acetylesterase activity
C0085_RS09850	COG0657	acetylesterase activity
C0085_RS09865	COG5651	PPE family
C0085_RS09875	COG1285	pathogenesis
C0085_RS09960	COG0509	glycine decarboxylation via glycine cleavage system
C0085_RS09985	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0085_RS09985	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0085_RS10035	COG1253	flavin adenine dinucleotide binding
C0085_RS10040	COG1253	flavin adenine dinucleotide binding
C0085_RS10050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C0085_RS10085	COG0830	nickel cation binding
C0085_RS10105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS10155	COG4221	oxidoreductase activity
C0085_RS10160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0085_RS10170	COG0183	Belongs to the thiolase family
C0085_RS10235	COG0174	glutamine synthetase
C0085_RS10255	COG0300	oxidoreductase activity
C0085_RS10265	COG1652	LysM domain
C0085_RS10275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C0085_RS10300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0085_RS10305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0085_RS10330	COG2070	2-Nitropropane dioxygenase
C0085_RS10350	COG1490	D-aminoacyl-tRNA deacylase activity
C0085_RS10360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C0085_RS10380	COG1950	PFAM Membrane protein of
C0085_RS10385	COG1366	Belongs to the anti-sigma-factor antagonist family
C0085_RS10405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0085_RS10440	COG2224	Isocitrate lyase
C0085_RS10450	COG5263	repeat protein
C0085_RS10450	COG5651	PPE family
C0085_RS10455	COG5651	PPE family
C0085_RS10455	COG5263	repeat protein
C0085_RS10475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0085_RS10480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0085_RS10490	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS10520	COG4977	sequence-specific DNA binding
C0085_RS10535	COG1960	acyl-CoA dehydrogenase activity
C0085_RS10540	COG1024	Enoyl-CoA hydratase
C0085_RS10555	COG0543	2 iron, 2 sulfur cluster binding
C0085_RS10555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0085_RS10560	COG0596	Alpha beta hydrolase
C0085_RS10570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0085_RS10570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0085_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS10580	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS10590	COG0653	protein targeting
C0085_RS10635	COG4691	Plasmid stability protein
C0085_RS10695	COG1309	transcriptional regulator
C0085_RS10740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0085_RS10820	COG1872	DUF167
C0085_RS10865	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS11030	COG2442	InterPro IPR007367
C0085_RS11045	COG1396	sequence-specific DNA binding
C0085_RS11050	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C0085_RS11115	COG0640	Transcriptional regulator
C0085_RS11130	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0085_RS11135	COG3842	ATPase activity
C0085_RS11140	COG0395	ABC-type sugar transport system, permease component
C0085_RS11145	COG1175	transmembrane transport
C0085_RS11160	COG1335	isochorismatase
C0085_RS11185	COG0604	alcohol dehydrogenase
C0085_RS11185	COG3321	synthase
C0085_RS11240	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0085_RS11260	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS11285	COG2367	Beta-lactamase
C0085_RS11305	COG2242	protein methyltransferase activity
C0085_RS11305	COG2241	protein methyltransferase activity
C0085_RS11310	COG0300	oxidoreductase activity
C0085_RS11345	COG1511	domain protein
C0085_RS11380	COG2801	Transposase and inactivated derivatives
C0085_RS11395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0085_RS11445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0085_RS11450	COG4279	zinc finger
C0085_RS11455	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0085_RS11465	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C0085_RS11490	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
C0085_RS11560	COG5651	PPE family
C0085_RS11565	COG0646	methionine synthase
C0085_RS11565	COG1410	methionine synthase
C0085_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS11645	COG0167	dihydroorotate dehydrogenase activity
C0085_RS11655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0085_RS11710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C0085_RS11725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0085_RS11775	COG0768	penicillin binding
C0085_RS11825	COG0142	geranyltranstransferase activity
C0085_RS11855	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C0085_RS11885	COG0003	Pfam Anion-transporting ATPase
C0085_RS11900	COG1022	Amp-dependent synthetase and ligase
C0085_RS11980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0085_RS12010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C0085_RS12035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0085_RS12055	COG0321	lipoyl(octanoyl) transferase activity
C0085_RS12110	COG3025	triphosphatase activity
C0085_RS12110	COG5607	PFAM CHAD domain containing protein
C0085_RS12145	COG3744	PilT protein domain protein
C0085_RS12170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C0085_RS12315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C0085_RS12320	COG4221	oxidoreductase activity
C0085_RS12390	COG0584	glycerophosphoryl diester phosphodiesterase
C0085_RS12420	COG0657	acetylesterase activity
C0085_RS12550	COG1073	alpha beta
C0085_RS12575	COG2442	InterPro IPR007367
C0085_RS12645	COG0395	ABC-type sugar transport system, permease component
C0085_RS12660	COG0531	amino acid
C0085_RS12665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0085_RS12670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0085_RS12675	COG1834	amidinotransferase
C0085_RS12680	COG1522	sequence-specific DNA binding
C0085_RS12710	COG2223	nitrite transmembrane transporter activity
C0085_RS12735	COG0477	Major facilitator Superfamily
C0085_RS12745	COG1045	serine acetyltransferase
C0085_RS12760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0085_RS12940	COG0657	acetylesterase activity
C0085_RS12955	COG1420	regulation of RNA biosynthetic process
C0085_RS12985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS13000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C0085_RS13000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS13005	COG1021	2,3-dihydroxybenzoate-AMP ligase
C0085_RS13065	COG1297	OPT oligopeptide transporter protein
C0085_RS13090	COG4208	sulfate ABC transporter
C0085_RS13100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0085_RS13115	COG3387	PFAM Glycoside hydrolase 15-related
C0085_RS13140	COG1234	tRNA 3'-trailer cleavage
C0085_RS13160	COG1305	Transglutaminase-like
C0085_RS13190	COG1596	polysaccharide export
C0085_RS13190	COG1555	photosystem II stabilization
C0085_RS13205	COG2755	lipolytic protein G-D-S-L family
C0085_RS13215	COG0799	negative regulation of ribosome biogenesis
C0085_RS13220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0085_RS13250	COG0542	response to heat
C0085_RS13280	COG5651	PPE family
C0085_RS13300	COG0668	transmembrane transport
C0085_RS13305	COG5002	protein histidine kinase activity
C0085_RS13315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0085_RS13335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0085_RS13360	COG1301	dicarboxylic acid transport
C0085_RS13365	COG1530	ribonuclease E activity
C0085_RS13380	COG0285	dihydrofolate synthase activity
C0085_RS13390	COG3268	Saccharopine dehydrogenase
C0085_RS13395	COG1388	LysM domain
C0085_RS13415	COG1013	pyruvate-flavodoxin oxidoreductase activity
C0085_RS13420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C0085_RS13420	COG0674	pyruvate-flavodoxin oxidoreductase activity
C0085_RS13430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C0085_RS13435	COG2040	homocysteine
C0085_RS13455	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0085_RS13470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0085_RS13485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0085_RS13515	COG0366	Alpha amylase catalytic
C0085_RS13535	COG0824	Thioesterase
C0085_RS13540	COG2902	Dehydrogenase
C0085_RS13590	COG0657	acetylesterase activity
C0085_RS13645	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0085_RS13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0085_RS13670	COG2030	dehydratase
C0085_RS13675	COG1960	acyl-CoA dehydrogenase activity
C0085_RS13685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0085_RS13700	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS13720	COG0300	oxidoreductase activity
C0085_RS13725	COG0433	COG0433 Predicted ATPase
C0085_RS13745	COG3328	transposase activity
C0085_RS13795	COG1376	ErfK ybiS ycfS ynhG family protein
C0085_RS13840	COG3757	hydrolase, family 25
C0085_RS13860	COG1715	Restriction endonuclease
C0085_RS13890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0085_RS13960	COG1487	ribonuclease activity
C0085_RS14005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0085_RS14015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0085_RS14020	COG0432	Pfam Uncharacterised protein family UPF0047
C0085_RS14040	COG5473	translation initiation factor activity
C0085_RS14140	COG0596	Alpha beta hydrolase
C0085_RS14175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0085_RS14200	COG1022	Amp-dependent synthetase and ligase
C0085_RS14200	COG3320	Male sterility
C0085_RS14280	COG1946	Acyl-CoA thioesterase
C0085_RS14295	COG5651	PPE family
C0085_RS14335	COG3391	amine dehydrogenase activity
C0085_RS14340	COG4762	Protein conserved in bacteria
C0085_RS14455	COG1366	Belongs to the anti-sigma-factor antagonist family
C0085_RS14475	COG0640	Transcriptional regulator
C0085_RS14480	COG0798	PFAM Bile acid sodium symporter
C0085_RS14490	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS14520	COG4974	Belongs to the 'phage' integrase family
C0085_RS14670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0085_RS14745	COG1131	(ABC) transporter
C0085_RS14760	COG0531	amino acid
C0085_RS14765	COG0569	domain protein
C0085_RS14905	COG1388	LysM domain
C0085_RS14910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0085_RS14930	COG1960	acyl-CoA dehydrogenase activity
C0085_RS14935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0085_RS14965	COG1196	nuclear chromosome segregation
C0085_RS15020	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
C0085_RS15030	COG3391	amine dehydrogenase activity
C0085_RS15045	COG1842	Phage shock protein A
C0085_RS15060	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0085_RS15105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C0085_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS15195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0085_RS15225	COG1522	sequence-specific DNA binding
C0085_RS15230	COG0686	Belongs to the AlaDH PNT family
C0085_RS15275	COG1960	acyl-CoA dehydrogenase activity
C0085_RS15280	COG0183	Belongs to the thiolase family
C0085_RS15300	COG2977	Belongs to the P-Pant transferase superfamily
C0085_RS15305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0085_RS15335	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS15340	COG3609	addiction module antidote protein, CC2985 family
C0085_RS15445	COG1353	crispr-associated protein
C0085_RS15480	COG3744	PilT protein domain protein
C0085_RS15485	COG4118	positive regulation of growth
C0085_RS15495	COG3842	ATPase activity
C0085_RS15500	COG1653	transport
C0085_RS15505	COG0395	ABC-type sugar transport system, permease component
C0085_RS15520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0085_RS15570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0085_RS15570	COG1648	precorrin-2 dehydrogenase activity
C0085_RS15615	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
C0085_RS15640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0085_RS15675	COG2161	toxin-antitoxin pair type II binding
C0085_RS15680	COG2026	Addiction module toxin, RelE StbE family
C0085_RS15760	COG0233	cytoplasmic translational termination
C0085_RS15775	COG0745	RESPONSE REGULATOR receiver
C0085_RS15800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0085_RS15910	COG1686	Belongs to the peptidase S11 family
C0085_RS15945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C0085_RS16035	COG3321	synthase
C0085_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS16035	COG0604	alcohol dehydrogenase
C0085_RS16110	COG0604	alcohol dehydrogenase
C0085_RS16110	COG3321	synthase
C0085_RS16110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS16110	COG4221	oxidoreductase activity
C0085_RS16115	COG3321	synthase
C0085_RS16130	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS16180	COG1819	glycosyl
C0085_RS16205	COG0701	Predicted permease
C0085_RS16230	COG0742	ribosomal rna small subunit methyltransferase
C0085_RS16240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C0085_RS16255	COG0657	acetylesterase activity
C0085_RS16260	COG0656	L-ascorbic acid biosynthetic process
C0085_RS16265	COG0656	L-ascorbic acid biosynthetic process
C0085_RS16280	COG1461	Dihydroxyacetone kinase
C0085_RS16325	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0085_RS16360	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0085_RS16390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0085_RS16395	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0085_RS16405	COG0473	3-isopropylmalate dehydrogenase activity
C0085_RS16430	COG2972	Histidine kinase
C0085_RS16440	COG0390	transport system, permease component
C0085_RS16465	COG2259	Doxx family
C0085_RS16495	COG0154	amidase activity
C0085_RS16560	COG3328	transposase activity
C0085_RS16625	COG0110	maltose O-acetyltransferase activity
C0085_RS16630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0085_RS16660	COG1119	ATPase activity
C0085_RS16665	COG3830	Belongs to the UPF0237 family
C0085_RS16665	COG0560	Phosphoserine phosphatase
C0085_RS16710	COG1309	transcriptional regulator
C0085_RS16770	COG2186	Transcriptional regulator
C0085_RS16775	COG1960	acyl-CoA dehydrogenase activity
C0085_RS16785	COG1966	Carbon starvation protein
C0085_RS16870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS16945	COG2354	Protein conserved in bacteria
C0085_RS16970	COG0657	acetylesterase activity
C0085_RS16980	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0085_RS17000	COG2177	Part of the ABC transporter FtsEX involved in
C0085_RS17005	COG2884	Cell division ATP-binding protein ftsE
C0085_RS17015	COG0668	transmembrane transport
C0085_RS17030	COG0277	FAD linked oxidase domain protein
C0085_RS17045	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0085_RS17055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0085_RS17075	COG3328	transposase activity
C0085_RS17125	COG3629	intracellular signal transduction
C0085_RS17150	COG2801	Transposase and inactivated derivatives
C0085_RS17210	COG0483	inositol monophosphate 1-phosphatase activity
C0085_RS17225	COG1960	acyl-CoA dehydrogenase activity
C0085_RS17230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS17230	COG0604	alcohol dehydrogenase
C0085_RS17230	COG3321	synthase
C0085_RS17230	COG4221	oxidoreductase activity
C0085_RS17280	COG1034	ATP synthesis coupled electron transport
C0085_RS17290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0085_RS17345	COG0714	Associated with various cellular activities
C0085_RS17390	COG1309	transcriptional regulator
C0085_RS17400	COG0154	amidase activity
C0085_RS17415	COG0748	coenzyme F420 binding
C0085_RS17445	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C0085_RS17450	COG1396	sequence-specific DNA binding
C0085_RS17490	COG2826	transposase and inactivated derivatives, IS30 family
C0085_RS17515	COG1615	UPF0182 protein
C0085_RS17540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0085_RS17560	COG2816	NAD+ diphosphatase activity
C0085_RS17570	COG0210	DNA helicase
C0085_RS17585	COG0596	Alpha beta hydrolase
C0085_RS17590	COG3695	enzyme binding
C0085_RS17630	COG0513	Belongs to the DEAD box helicase family
C0085_RS17645	COG0406	alpha-ribazole phosphatase activity
C0085_RS17665	COG1597	lipid kinase activity
C0085_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS17715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0085_RS17725	COG2135	peptidase activity
C0085_RS17730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C0085_RS17735	COG1162	GTPase activity
C0085_RS17755	COG2326	polyphosphate kinase activity
C0085_RS17770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0085_RS17770	COG4651	solute:proton antiporter activity
C0085_RS17780	COG2020	methyltransferase activity
C0085_RS17795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0085_RS17815	COG5000	phosphorelay sensor kinase activity
C0085_RS17815	COG5002	protein histidine kinase activity
C0085_RS17850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0085_RS17855	COG0531	amino acid
C0085_RS17860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0085_RS17865	COG1482	cell wall glycoprotein biosynthetic process
C0085_RS17875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0085_RS17935	COG1316	TRANSCRIPTIONal
C0085_RS17960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0085_RS17965	COG0659	secondary active sulfate transmembrane transporter activity
C0085_RS18000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0085_RS18010	COG0424	maF-like protein
C0085_RS18025	COG4770	biotin carboxylase activity
C0085_RS18055	COG1522	sequence-specific DNA binding
C0085_RS18065	COG1012	belongs to the aldehyde dehydrogenase family
C0085_RS18075	COG1309	transcriptional regulator
C0085_RS18080	COG1201	RNA secondary structure unwinding
C0085_RS18095	COG3119	arylsulfatase activity
C0085_RS18095	COG3408	Glycogen debranching enzyme
C0085_RS18100	COG0564	pseudouridine synthase activity
C0085_RS18125	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C0085_RS18125	COG1473	amidohydrolase
C0085_RS18140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0085_RS18150	COG3511	phospholipase C
C0085_RS18190	COG2009	succinate dehydrogenase
C0085_RS18200	COG1053	succinate dehydrogenase
C0085_RS18205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0085_RS18245	COG3547	Transposase (IS116 IS110 IS902 family)
C0085_RS18250	COG1595	DNA-templated transcription, initiation
C0085_RS18255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0085_RS18260	COG1686	Belongs to the peptidase S11 family
C0085_RS18265	COG2814	Major facilitator Superfamily
C0085_RS18270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0085_RS18285	COG0789	Transcriptional regulator
C0085_RS18290	COG1295	ribonuclease BN
C0085_RS18310	COG2873	o-acetylhomoserine
C0085_RS18325	COG5651	PPE family
C0085_RS18340	COG5651	PPE family
C0085_RS18340	COG5651	PPE family
C0085_RS18370	COG5651	PPE family
C0085_RS18370	COG5651	PPE family
C0085_RS18370	COG5651	PPE family
C0085_RS18380	COG0277	FAD linked oxidase domain protein
C0085_RS18405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0085_RS18425	COG1716	ATPase activity
C0085_RS18425	COG1131	(ABC) transporter
C0085_RS18425	COG0842	Transport permease protein
C0085_RS18430	COG1357	PFAM Pentapeptide repeats (8 copies)
C0085_RS18445	COG2018	Roadblock/LC7 domain
C0085_RS18455	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0085_RS18480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS18495	COG1024	Enoyl-CoA hydratase
C0085_RS18515	COG1657	PFAM Prenyltransferase squalene oxidase
C0085_RS18525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0085_RS18530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0085_RS18545	COG0142	geranyltranstransferase activity
C0085_RS18550	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
C0085_RS18570	COG2030	dehydratase
C0085_RS18575	COG0406	alpha-ribazole phosphatase activity
C0085_RS18585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS18735	COG0456	acetyltransferase
C0085_RS18765	COG5651	PPE family
C0085_RS18780	COG4584	PFAM Integrase catalytic
C0085_RS18810	COG0076	glutamate decarboxylase activity
C0085_RS18870	COG4842	Belongs to the WXG100 family
C0085_RS18875	COG4842	Belongs to the WXG100 family
C0085_RS18885	COG1674	ftsk spoiiie
C0085_RS18895	COG1404	Belongs to the peptidase S8 family
C0085_RS18950	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0085_RS18965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0085_RS18995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0085_RS19000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0085_RS19005	COG0028	Belongs to the TPP enzyme family
C0085_RS19030	COG0477	Major facilitator Superfamily
C0085_RS19040	COG5651	PPE family
C0085_RS19045	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0085_RS19050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS19070	COG1316	TRANSCRIPTIONal
C0085_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS19085	COG2259	Doxx family
C0085_RS19090	COG0657	acetylesterase activity
C0085_RS19095	COG1695	Transcriptional regulator
C0085_RS19105	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C0085_RS19130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0085_RS19155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0085_RS19160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0085_RS19175	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19180	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS19190	COG0657	acetylesterase activity
C0085_RS19195	COG0657	acetylesterase activity
C0085_RS19200	COG0028	Belongs to the TPP enzyme family
C0085_RS19220	COG0657	acetylesterase activity
C0085_RS19235	COG1024	Enoyl-CoA hydratase
C0085_RS19245	COG2124	cytochrome p450
C0085_RS19255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0085_RS19265	COG0183	Belongs to the thiolase family
C0085_RS19270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C0085_RS19285	COG4638	Rieske (2fe-2S)
C0085_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS19345	COG3971	2-oxopent-4-enoate hydratase activity
C0085_RS19350	COG1053	succinate dehydrogenase
C0085_RS19355	COG2030	dehydratase
C0085_RS19375	COG2030	dehydratase
C0085_RS19380	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19385	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19395	COG0183	Belongs to the thiolase family
C0085_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS19420	COG1024	Enoyl-CoA hydratase
C0085_RS19440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0085_RS19450	COG0183	Belongs to the thiolase family
C0085_RS19470	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19475	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS19480	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19485	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19490	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19495	COG0436	Aminotransferase
C0085_RS19545	COG1960	acyl-CoA dehydrogenase activity
C0085_RS19550	COG1309	transcriptional regulator
C0085_RS19555	COG1609	Transcriptional regulator
C0085_RS19575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0085_RS19610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C0085_RS19630	COG0657	acetylesterase activity
C0085_RS19650	COG0739	heme binding
C0085_RS19730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0085_RS19770	COG2267	carboxylic ester hydrolase activity
C0085_RS19820	COG2027	D-alanyl-D-alanine carboxypeptidase
C0085_RS19835	COG2244	polysaccharide biosynthetic process
C0085_RS19880	COG3328	transposase activity
C0085_RS19885	COG2184	nucleotidyltransferase activity
C0085_RS19905	COG0470	DNA polymerase III
C0085_RS19930	COG1111	helicase
C0085_RS19930	COG1205	dead DEAH box helicase
C0085_RS19935	COG0657	acetylesterase activity
C0085_RS19955	COG0657	acetylesterase activity
C0085_RS20015	COG4172	Belongs to the ABC transporter superfamily
C0085_RS20020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0085_RS20025	COG0601	transmembrane transport
C0085_RS20065	COG0494	nUDIX hydrolase
C0085_RS20090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0085_RS20125	COG1408	metallophosphoesterase
C0085_RS20130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0085_RS20180	COG0714	Associated with various cellular activities
C0085_RS20205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C0085_RS20230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0085_RS20240	COG0121	glutamine amidotransferase
C0085_RS20245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0085_RS20295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C0085_RS20320	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0085_RS20335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0085_RS20345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0085_RS20375	COG1063	alcohol dehydrogenase
C0085_RS20380	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C0085_RS20380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0085_RS20385	COG0477	Major facilitator Superfamily
C0085_RS20390	COG2226	methyltransferase
C0085_RS20400	COG1793	dna ligase
C0085_RS20450	COG2072	flavoprotein involved in K transport
C0085_RS20460	COG0640	Transcriptional regulator
C0085_RS20485	COG1569	PIN domain
C0085_RS20490	COG3311	Transcriptional regulator
C0085_RS20510	COG0590	tRNA wobble adenosine to inosine editing
C0085_RS20520	COG0287	Prephenate dehydrogenase
C0085_RS20540	COG0517	IMP dehydrogenase activity
C0085_RS20540	COG1125	glycine betaine transport
C0085_RS20550	COG5416	Lipopolysaccharide assembly protein A domain
C0085_RS20560	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C0085_RS20570	COG2205	protein histidine kinase activity
C0085_RS20575	COG0745	RESPONSE REGULATOR receiver
C0085_RS20580	COG0739	heme binding
C0085_RS20625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0085_RS20690	COG1088	dTDP-glucose 4,6-dehydratase activity
C0085_RS20735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0085_RS20750	COG1234	tRNA 3'-trailer cleavage
C0085_RS20755	COG1960	acyl-CoA dehydrogenase activity
C0085_RS20765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0085_RS20770	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C0085_RS20770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0085_RS20770	COG3321	synthase
C0085_RS20775	COG0318	PFAM AMP-dependent synthetase and ligase
C0085_RS20780	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0085_RS20795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0085_RS20810	COG1216	Glycosyl transferase, family 2
C0085_RS20830	COG0657	acetylesterase activity
C0085_RS20845	COG0561	phosphatase activity
C0085_RS20880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0085_RS20890	COG5651	PPE family
C0085_RS20895	COG1511	domain protein
C0085_RS20895	COG2409	Drug exporters of the RND superfamily
C0085_RS20905	COG0604	alcohol dehydrogenase
C0085_RS20905	COG3321	synthase
C0085_RS20905	COG1028	Short-chain dehydrogenase reductase Sdr
C0085_RS20950	COG2207	Transcriptional regulator
C0085_RS20990	COG1316	TRANSCRIPTIONal
C0085_RS21060	COG2119	membrane
C0085_RS21100	COG1796	DNA polymerase
C0085_RS21100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C0085_RS21115	COG0069	glutamate synthase activity
C0085_RS21115	COG0067	glutamate synthase
C0085_RS21115	COG0070	glutamate synthase
C0085_RS21225	COG4932	domain protein
C0085_RS21245	COG1404	Belongs to the peptidase S8 family
C0085_RS21250	COG0464	growth
C0085_RS21260	COG1404	Belongs to the peptidase S8 family
C0085_RS21290	COG5651	PPE family
C0085_RS21300	COG1674	ftsk spoiiie
C0085_RS21390	COG1595	DNA-templated transcription, initiation
C0085_RS21410	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0085_RS21410	COG3409	Peptidoglycan-binding domain 1 protein
C0085_RS21430	COG1192	Involved in chromosome partitioning
C0085_RS21450	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0085_RS21460	COG0230	Belongs to the bacterial ribosomal protein bL34 family