locus-tag	class	description
TBMG_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TBMG_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
TBMG_RS00090	COG0515	serine threonine protein kinase
TBMG_RS00115	COG1716	ATPase activity
TBMG_RS00185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TBMG_RS00195	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS00245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TBMG_RS00245	COG0596	Alpha beta hydrolase
TBMG_RS00250	COG1260	myo-inositol-1-phosphate synthase
TBMG_RS00270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TBMG_RS00340	COG0277	FAD linked oxidase domain protein
TBMG_RS00365	COG1309	transcriptional regulator
TBMG_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS00385	COG3344	reverse transcriptase
TBMG_RS00400	COG1228	amidohydrolase
TBMG_RS00420	COG1309	transcriptional regulator
TBMG_RS00450	COG3260	NADH ubiquinone oxidoreductase 20
TBMG_RS00460	COG0650	Formate hydrogenlyase subunit 4
TBMG_RS00470	COG0651	ATP synthesis coupled electron transport
TBMG_RS00475	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBMG_RS00475	COG3261	NADH dehydrogenase
TBMG_RS00515	COG1403	HNH endonuclease
TBMG_RS00545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS00585	COG0657	acetylesterase activity
TBMG_RS00595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TBMG_RS00595	COG2755	lipolytic protein G-D-S-L family
TBMG_RS00625	COG1376	ErfK ybiS ycfS ynhG family protein
TBMG_RS00630	COG0583	DNA-binding transcription factor activity
TBMG_RS00635	COG0028	Belongs to the TPP enzyme family
TBMG_RS00675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBMG_RS00710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS00720	COG0596	Alpha beta hydrolase
TBMG_RS00765	COG0038	chloride channel
TBMG_RS00770	COG1309	transcriptional regulator
TBMG_RS00785	COG1012	belongs to the aldehyde dehydrogenase family
TBMG_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS00795	COG3321	synthase
TBMG_RS00795	COG0604	alcohol dehydrogenase
TBMG_RS00820	COG2365	Tyrosine phosphatase family
TBMG_RS00855	COG1309	transcriptional regulator
TBMG_RS00860	COG0657	acetylesterase activity
TBMG_RS00860	COG5651	PPE family
TBMG_RS00865	COG5651	PPE family
TBMG_RS00865	COG0657	acetylesterase activity
TBMG_RS00870	COG0277	FAD linked oxidase domain protein
TBMG_RS00875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TBMG_RS00890	COG1802	Transcriptional regulator
TBMG_RS00900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBMG_RS00905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBMG_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBMG_RS00980	COG2267	carboxylic ester hydrolase activity
TBMG_RS00995	COG1472	Belongs to the glycosyl hydrolase 3 family
TBMG_RS01005	COG4122	O-methyltransferase activity
TBMG_RS01020	COG1937	Protein conserved in bacteria
TBMG_RS01025	COG2814	Major facilitator Superfamily
TBMG_RS01030	COG1376	ErfK ybiS ycfS ynhG family protein
TBMG_RS01040	COG1132	(ABC) transporter
TBMG_RS01055	COG0243	molybdopterin cofactor binding
TBMG_RS01060	COG3590	peptidase
TBMG_RS01100	COG2409	Drug exporters of the RND superfamily
TBMG_RS01155	COG0657	acetylesterase activity
TBMG_RS01160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TBMG_RS01170	COG0657	acetylesterase activity
TBMG_RS01180	COG1024	Enoyl-CoA hydratase
TBMG_RS01190	COG0500	methyltransferase
TBMG_RS01195	COG0297	glycogen (starch) synthase activity
TBMG_RS01215	COG1487	ribonuclease activity
TBMG_RS01255	COG4981	capsule polysaccharide biosynthetic process
TBMG_RS01265	COG1472	Belongs to the glycosyl hydrolase 3 family
TBMG_RS01285	COG2030	dehydratase
TBMG_RS01295	COG0183	Belongs to the thiolase family
TBMG_RS01300	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS01320	COG1053	succinate dehydrogenase
TBMG_RS01340	COG2146	nitrite reductase [NAD(P)H] activity
TBMG_RS01340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TBMG_RS01360	COG5651	PPE family
TBMG_RS01395	COG1984	allophanate hydrolase subunit 2
TBMG_RS01415	COG2223	nitrite transmembrane transporter activity
TBMG_RS01420	COG2161	toxin-antitoxin pair type II binding
TBMG_RS01430	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS01435	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS01450	COG0346	lactoylglutathione lyase activity
TBMG_RS01480	COG3391	amine dehydrogenase activity
TBMG_RS01545	COG1404	Belongs to the peptidase S8 family
TBMG_RS01570	COG1368	sulfuric ester hydrolase activity
TBMG_RS01575	COG3391	amine dehydrogenase activity
TBMG_RS01615	COG0778	Nitroreductase
TBMG_RS01625	COG0671	phosphoesterase, PA-phosphatase related
TBMG_RS01695	COG0717	Belongs to the dCTP deaminase family
TBMG_RS01700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TBMG_RS01705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TBMG_RS01720	COG2226	methyltransferase
TBMG_RS01735	COG2226	methyltransferase
TBMG_RS01745	COG1252	NADH dehydrogenase
TBMG_RS01780	COG0247	lactate metabolic process
TBMG_RS01780	COG2181	nitrate reductase activity
TBMG_RS01855	COG0789	Transcriptional regulator
TBMG_RS01865	COG5651	PPE family
TBMG_RS01865	COG5263	repeat protein
TBMG_RS01885	COG1994	Peptidase M50
TBMG_RS01900	COG2239	Acts as a magnesium transporter
TBMG_RS01945	COG0746	molybdenum cofactor guanylyltransferase activity
TBMG_RS01970	COG3360	Dodecin
TBMG_RS02015	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
TBMG_RS02030	COG1252	NADH dehydrogenase
TBMG_RS02035	COG1403	HNH endonuclease
TBMG_RS02075	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS02100	COG0604	alcohol dehydrogenase
TBMG_RS02100	COG3321	synthase
TBMG_RS02100	COG0604	alcohol dehydrogenase
TBMG_RS02100	COG3321	synthase
TBMG_RS02105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBMG_RS02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TBMG_RS02165	COG2234	aminopeptidase activity
TBMG_RS02200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TBMG_RS02255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBMG_RS02260	COG1183	phosphatidylcholine synthase activity
TBMG_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS02300	COG5343	regulation of RNA biosynthetic process
TBMG_RS02315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS02360	COG1024	Enoyl-CoA hydratase
TBMG_RS02365	COG2337	Toxic component of a toxin-antitoxin (TA) module
TBMG_RS02375	COG1505	serine-type exopeptidase activity
TBMG_RS02435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS02460	COG2733	membrane
TBMG_RS02665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TBMG_RS02665	COG1648	precorrin-2 dehydrogenase activity
TBMG_RS02690	COG1366	Belongs to the anti-sigma-factor antagonist family
TBMG_RS02695	COG2755	lipolytic protein G-D-S-L family
TBMG_RS02695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TBMG_RS02700	COG2755	lipolytic protein G-D-S-L family
TBMG_RS02720	COG1113	amino acid transport
TBMG_RS02735	COG0406	alpha-ribazole phosphatase activity
TBMG_RS02745	COG0785	Cytochrome C biogenesis protein
TBMG_RS02755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TBMG_RS02775	COG3391	amine dehydrogenase activity
TBMG_RS02790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TBMG_RS02795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBMG_RS02850	COG4221	oxidoreductase activity
TBMG_RS02870	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS02875	COG1228	amidohydrolase
TBMG_RS02925	COG0142	geranyltranstransferase activity
TBMG_RS02940	COG2072	flavoprotein involved in K transport
TBMG_RS02955	COG2345	Transcriptional regulator
TBMG_RS02970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TBMG_RS03030	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
TBMG_RS03040	COG3537	Alpha-1,2-mannosidase
TBMG_RS03060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBMG_RS03085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBMG_RS03095	COG1487	ribonuclease activity
TBMG_RS03115	COG2002	toxin-antitoxin pair type II binding
TBMG_RS03125	COG2972	Histidine kinase
TBMG_RS03130	COG0745	RESPONSE REGULATOR receiver
TBMG_RS03195	COG0653	protein targeting
TBMG_RS03230	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TBMG_RS03270	COG1487	ribonuclease activity
TBMG_RS03290	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
TBMG_RS03335	COG2030	dehydratase
TBMG_RS03365	COG0081	regulation of translation
TBMG_RS03370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS03375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS03380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS03385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS03425	COG1309	transcriptional regulator
TBMG_RS03500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TBMG_RS03525	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS03540	COG1024	Enoyl-CoA hydratase
TBMG_RS03555	COG1510	regulation of RNA biosynthetic process
TBMG_RS03570	COG1309	transcriptional regulator
TBMG_RS03630	COG0535	radical SAM domain protein
TBMG_RS03740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TBMG_RS03795	COG0200	Binds to the 23S rRNA
TBMG_RS03800	COG0616	signal peptide processing
TBMG_RS03815	COG0235	Class ii aldolase
TBMG_RS03820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBMG_RS03890	COG0657	acetylesterase activity
TBMG_RS03960	COG0406	alpha-ribazole phosphatase activity
TBMG_RS03985	COG0745	RESPONSE REGULATOR receiver
TBMG_RS03990	COG2205	protein histidine kinase activity
TBMG_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS04090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TBMG_RS04120	COG0477	Major facilitator Superfamily
TBMG_RS04145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TBMG_RS04165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS04170	COG2188	Transcriptional regulator
TBMG_RS04175	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
TBMG_RS04180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TBMG_RS04190	COG3547	Transposase (IS116 IS110 IS902 family)
TBMG_RS04200	COG2837	iron assimilation
TBMG_RS04250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TBMG_RS04300	COG0745	RESPONSE REGULATOR receiver
TBMG_RS04345	COG0640	Transcriptional regulator
TBMG_RS04350	COG0590	tRNA wobble adenosine to inosine editing
TBMG_RS04410	COG2801	Transposase and inactivated derivatives
TBMG_RS04415	COG2963	transposase activity
TBMG_RS04425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TBMG_RS04435	COG2154	pterin-4-alpha-carbinolamine dehydratase
TBMG_RS04455	COG0277	FAD linked oxidase domain protein
TBMG_RS04470	COG0668	transmembrane transport
TBMG_RS04480	COG2884	Cell division ATP-binding protein ftsE
TBMG_RS04485	COG2177	Part of the ABC transporter FtsEX involved in
TBMG_RS04500	COG2337	Toxic component of a toxin-antitoxin (TA) module
TBMG_RS04510	COG0657	acetylesterase activity
TBMG_RS04535	COG2354	Protein conserved in bacteria
TBMG_RS04600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS04685	COG1966	Carbon starvation protein
TBMG_RS04700	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS04705	COG2186	Transcriptional regulator
TBMG_RS04755	COG1309	transcriptional regulator
TBMG_RS04800	COG3830	Belongs to the UPF0237 family
TBMG_RS04800	COG0560	Phosphoserine phosphatase
TBMG_RS04805	COG1119	ATPase activity
TBMG_RS04835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TBMG_RS04840	COG0110	maltose O-acetyltransferase activity
TBMG_RS04900	COG3328	transposase activity
TBMG_RS04965	COG0154	amidase activity
TBMG_RS04995	COG2259	Doxx family
TBMG_RS05020	COG0390	transport system, permease component
TBMG_RS05030	COG2972	Histidine kinase
TBMG_RS05055	COG2271	Major facilitator Superfamily
TBMG_RS05060	COG0179	Fumarylacetoacetate (FAA) hydrolase
TBMG_RS05065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TBMG_RS05095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TBMG_RS05170	COG1461	Dihydroxyacetone kinase
TBMG_RS05185	COG0656	L-ascorbic acid biosynthetic process
TBMG_RS05190	COG0656	L-ascorbic acid biosynthetic process
TBMG_RS05195	COG0657	acetylesterase activity
TBMG_RS05210	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TBMG_RS05215	COG0742	ribosomal rna small subunit methyltransferase
TBMG_RS05235	COG0701	Predicted permease
TBMG_RS05260	COG1819	glycosyl
TBMG_RS05305	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS05390	COG3321	synthase
TBMG_RS05390	COG0604	alcohol dehydrogenase
TBMG_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS05505	COG1686	Belongs to the peptidase S11 family
TBMG_RS05610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TBMG_RS05635	COG0745	RESPONSE REGULATOR receiver
TBMG_RS05645	COG0233	cytoplasmic translational termination
TBMG_RS05725	COG2026	Addiction module toxin, RelE StbE family
TBMG_RS05730	COG2161	toxin-antitoxin pair type II binding
TBMG_RS05765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TBMG_RS05790	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
TBMG_RS05835	COG1648	precorrin-2 dehydrogenase activity
TBMG_RS05835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TBMG_RS05885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TBMG_RS05900	COG0395	ABC-type sugar transport system, permease component
TBMG_RS05905	COG1653	transport
TBMG_RS05910	COG3842	ATPase activity
TBMG_RS05920	COG4118	positive regulation of growth
TBMG_RS05925	COG3744	PilT protein domain protein
TBMG_RS05960	COG1353	crispr-associated protein
TBMG_RS06000	COG2963	transposase activity
TBMG_RS06005	COG2801	Transposase and inactivated derivatives
TBMG_RS06070	COG3609	addiction module antidote protein, CC2985 family
TBMG_RS06075	COG2337	Toxic component of a toxin-antitoxin (TA) module
TBMG_RS06105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TBMG_RS06110	COG2977	Belongs to the P-Pant transferase superfamily
TBMG_RS06130	COG0183	Belongs to the thiolase family
TBMG_RS06135	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS06180	COG0686	Belongs to the AlaDH PNT family
TBMG_RS06185	COG1522	sequence-specific DNA binding
TBMG_RS06210	COG2801	Transposase and inactivated derivatives
TBMG_RS06215	COG2963	transposase activity
TBMG_RS06230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TBMG_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS06315	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TBMG_RS06360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TBMG_RS06375	COG1842	Phage shock protein A
TBMG_RS06390	COG3391	amine dehydrogenase activity
TBMG_RS06395	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
TBMG_RS06445	COG1196	nuclear chromosome segregation
TBMG_RS06475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TBMG_RS06480	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS06500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TBMG_RS06505	COG1388	LysM domain
TBMG_RS06645	COG0569	domain protein
TBMG_RS06650	COG0531	amino acid
TBMG_RS06730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TBMG_RS06770	COG3328	transposase activity
TBMG_RS06860	COG4974	Belongs to the 'phage' integrase family
TBMG_RS06895	COG0798	PFAM Bile acid sodium symporter
TBMG_RS06900	COG0640	Transcriptional regulator
TBMG_RS06920	COG1366	Belongs to the anti-sigma-factor antagonist family
TBMG_RS07035	COG4762	Protein conserved in bacteria
TBMG_RS07040	COG3391	amine dehydrogenase activity
TBMG_RS07080	COG5651	PPE family
TBMG_RS07095	COG1946	Acyl-CoA thioesterase
TBMG_RS07175	COG1022	Amp-dependent synthetase and ligase
TBMG_RS07175	COG3320	Male sterility
TBMG_RS07195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TBMG_RS07230	COG0596	Alpha beta hydrolase
TBMG_RS07345	COG0432	Pfam Uncharacterised protein family UPF0047
TBMG_RS07350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TBMG_RS07360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TBMG_RS07400	COG1487	ribonuclease activity
TBMG_RS07465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TBMG_RS07495	COG1715	Restriction endonuclease
TBMG_RS07510	COG3757	hydrolase, family 25
TBMG_RS07550	COG1376	ErfK ybiS ycfS ynhG family protein
TBMG_RS07590	COG3328	transposase activity
TBMG_RS07605	COG0433	COG0433 Predicted ATPase
TBMG_RS07610	COG0300	oxidoreductase activity
TBMG_RS07630	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS07645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBMG_RS07655	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS07660	COG2030	dehydratase
TBMG_RS07680	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBMG_RS07685	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
TBMG_RS07695	COG2801	Transposase and inactivated derivatives
TBMG_RS07700	COG2963	transposase activity
TBMG_RS07735	COG0657	acetylesterase activity
TBMG_RS07750	COG0657	acetylesterase activity
TBMG_RS07785	COG2902	Dehydrogenase
TBMG_RS07790	COG0824	Thioesterase
TBMG_RS07810	COG0366	Alpha amylase catalytic
TBMG_RS07840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TBMG_RS07855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TBMG_RS07870	COG0544	peptidyl-prolyl cis-trans isomerase activity
TBMG_RS07890	COG2040	homocysteine
TBMG_RS07895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TBMG_RS07905	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBMG_RS07905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TBMG_RS07910	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBMG_RS07930	COG1388	LysM domain
TBMG_RS07935	COG3268	Saccharopine dehydrogenase
TBMG_RS07945	COG0285	dihydrofolate synthase activity
TBMG_RS07960	COG1530	ribonuclease E activity
TBMG_RS07965	COG1301	dicarboxylic acid transport
TBMG_RS07985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TBMG_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBMG_RS08005	COG5002	protein histidine kinase activity
TBMG_RS08010	COG0668	transmembrane transport
TBMG_RS08030	COG5651	PPE family
TBMG_RS08060	COG0542	response to heat
TBMG_RS08095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TBMG_RS08100	COG0799	negative regulation of ribosome biogenesis
TBMG_RS08110	COG2755	lipolytic protein G-D-S-L family
TBMG_RS08125	COG1596	polysaccharide export
TBMG_RS08125	COG1555	photosystem II stabilization
TBMG_RS08155	COG1305	Transglutaminase-like
TBMG_RS08190	COG3387	PFAM Glycoside hydrolase 15-related
TBMG_RS08205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
TBMG_RS08215	COG4208	sulfate ABC transporter
TBMG_RS08240	COG1297	OPT oligopeptide transporter protein
TBMG_RS08300	COG1021	2,3-dihydroxybenzoate-AMP ligase
TBMG_RS08305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS08305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
TBMG_RS08320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS08350	COG1420	regulation of RNA biosynthetic process
TBMG_RS08365	COG0657	acetylesterase activity
TBMG_RS08460	COG2963	transposase activity
TBMG_RS08465	COG2801	Transposase and inactivated derivatives
TBMG_RS08545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TBMG_RS08560	COG1045	serine acetyltransferase
TBMG_RS08570	COG0477	Major facilitator Superfamily
TBMG_RS08595	COG2223	nitrite transmembrane transporter activity
TBMG_RS08625	COG1522	sequence-specific DNA binding
TBMG_RS08630	COG1834	amidinotransferase
TBMG_RS08635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TBMG_RS08640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TBMG_RS08645	COG0531	amino acid
TBMG_RS08660	COG0395	ABC-type sugar transport system, permease component
TBMG_RS08720	COG2442	InterPro IPR007367
TBMG_RS08740	COG1073	alpha beta
TBMG_RS08855	COG0657	acetylesterase activity
TBMG_RS08865	COG2963	transposase activity
TBMG_RS08870	COG2801	Transposase and inactivated derivatives
TBMG_RS08960	COG4221	oxidoreductase activity
TBMG_RS08965	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TBMG_RS09130	COG3744	PilT protein domain protein
TBMG_RS09215	COG0321	lipoyl(octanoyl) transferase activity
TBMG_RS09235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TBMG_RS09260	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TBMG_RS09290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBMG_RS09365	COG1022	Amp-dependent synthetase and ligase
TBMG_RS09380	COG0003	Pfam Anion-transporting ATPase
TBMG_RS09410	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
TBMG_RS09435	COG0142	geranyltranstransferase activity
TBMG_RS09475	COG0768	penicillin binding
TBMG_RS09530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TBMG_RS09545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TBMG_RS09600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBMG_RS09610	COG0167	dihydroorotate dehydrogenase activity
TBMG_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS09695	COG0646	methionine synthase
TBMG_RS09695	COG1410	methionine synthase
TBMG_RS09700	COG5651	PPE family
TBMG_RS09775	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TBMG_RS09790	COG2963	transposase activity
TBMG_RS09795	COG2801	Transposase and inactivated derivatives
TBMG_RS09800	COG2963	transposase activity
TBMG_RS09805	COG2801	Transposase and inactivated derivatives
TBMG_RS09810	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TBMG_RS09820	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
TBMG_RS09825	COG4279	zinc finger
TBMG_RS09830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TBMG_RS09910	COG2801	Transposase and inactivated derivatives
TBMG_RS09985	COG0300	oxidoreductase activity
TBMG_RS10010	COG2367	Beta-lactamase
TBMG_RS10035	COG2337	Toxic component of a toxin-antitoxin (TA) module
TBMG_RS10060	COG0803	Belongs to the bacterial solute-binding protein 9 family
TBMG_RS10120	COG0604	alcohol dehydrogenase
TBMG_RS10120	COG3321	synthase
TBMG_RS10145	COG1335	isochorismatase
TBMG_RS10160	COG1175	transmembrane transport
TBMG_RS10165	COG0395	ABC-type sugar transport system, permease component
TBMG_RS10170	COG3842	ATPase activity
TBMG_RS10175	COG1752	Esterase of the alpha-beta hydrolase superfamily
TBMG_RS10190	COG0640	Transcriptional regulator
TBMG_RS10265	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
TBMG_RS10270	COG1396	sequence-specific DNA binding
TBMG_RS10285	COG2801	Transposase and inactivated derivatives
TBMG_RS10290	COG2963	transposase activity
TBMG_RS10295	COG2442	InterPro IPR007367
TBMG_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS10485	COG1872	DUF167
TBMG_RS10565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBMG_RS10605	COG1309	transcriptional regulator
TBMG_RS10665	COG4691	Plasmid stability protein
TBMG_RS10710	COG0653	protein targeting
TBMG_RS10720	COG2337	Toxic component of a toxin-antitoxin (TA) module
TBMG_RS10725	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS10730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TBMG_RS10730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TBMG_RS10740	COG0596	Alpha beta hydrolase
TBMG_RS10745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TBMG_RS10745	COG0543	2 iron, 2 sulfur cluster binding
TBMG_RS10755	COG1024	Enoyl-CoA hydratase
TBMG_RS10760	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS10765	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS10775	COG4977	sequence-specific DNA binding
TBMG_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS10805	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS10815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TBMG_RS10820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TBMG_RS10840	COG5263	repeat protein
TBMG_RS10840	COG5651	PPE family
TBMG_RS10845	COG5651	PPE family
TBMG_RS10845	COG5263	repeat protein
TBMG_RS10855	COG2224	Isocitrate lyase
TBMG_RS10890	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
TBMG_RS10910	COG1366	Belongs to the anti-sigma-factor antagonist family
TBMG_RS10915	COG1950	PFAM Membrane protein of
TBMG_RS10945	COG1490	D-aminoacyl-tRNA deacylase activity
TBMG_RS10955	COG1063	alcohol dehydrogenase
TBMG_RS10960	COG2070	2-Nitropropane dioxygenase
TBMG_RS11000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
TBMG_RS11020	COG0300	oxidoreductase activity
TBMG_RS11040	COG0174	glutamine synthetase
TBMG_RS11095	COG0183	Belongs to the thiolase family
TBMG_RS11100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TBMG_RS11105	COG4221	oxidoreductase activity
TBMG_RS11155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS11175	COG0830	nickel cation binding
TBMG_RS11210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TBMG_RS11220	COG1253	flavin adenine dinucleotide binding
TBMG_RS11225	COG1253	flavin adenine dinucleotide binding
TBMG_RS11270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TBMG_RS11270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TBMG_RS11300	COG0509	glycine decarboxylation via glycine cleavage system
TBMG_RS11375	COG1285	pathogenesis
TBMG_RS11400	COG0657	acetylesterase activity
TBMG_RS11410	COG2963	transposase activity
TBMG_RS11415	COG2801	Transposase and inactivated derivatives
TBMG_RS11425	COG0657	acetylesterase activity
TBMG_RS11440	COG5651	PPE family
TBMG_RS11460	COG1404	Belongs to the peptidase S8 family
TBMG_RS11490	COG5651	PPE family
TBMG_RS11495	COG5651	PPE family
TBMG_RS11505	COG5651	PPE family
TBMG_RS11605	COG1937	Protein conserved in bacteria
TBMG_RS11650	COG2963	transposase activity
TBMG_RS11655	COG2801	Transposase and inactivated derivatives
TBMG_RS11665	COG5651	PPE family
TBMG_RS11665	COG5263	repeat protein
TBMG_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS11695	COG1716	ATPase activity
TBMG_RS11695	COG0842	Transport permease protein
TBMG_RS11695	COG1131	(ABC) transporter
TBMG_RS11705	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TBMG_RS11855	COG3246	L-lysine catabolic process to acetate
TBMG_RS11895	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TBMG_RS11900	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TBMG_RS11910	COG0659	secondary active sulfate transmembrane transporter activity
TBMG_RS11925	COG5651	PPE family
TBMG_RS11930	COG1113	amino acid transport
TBMG_RS11935	COG4122	O-methyltransferase activity
TBMG_RS11950	COG0494	nUDIX hydrolase
TBMG_RS11990	COG0647	UMP catabolic process
TBMG_RS12030	COG2835	tetraacyldisaccharide 4'-kinase activity
TBMG_RS12050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
TBMG_RS12055	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS12110	COG0488	(ABC) transporter
TBMG_RS12125	COG3321	synthase
TBMG_RS12125	COG0604	alcohol dehydrogenase
TBMG_RS12125	COG3321	synthase
TBMG_RS12125	COG0604	alcohol dehydrogenase
TBMG_RS12130	COG4221	oxidoreductase activity
TBMG_RS12130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS12130	COG0604	alcohol dehydrogenase
TBMG_RS12130	COG3321	synthase
TBMG_RS12135	COG0604	alcohol dehydrogenase
TBMG_RS12135	COG3321	synthase
TBMG_RS12140	COG3321	synthase
TBMG_RS12140	COG0604	alcohol dehydrogenase
TBMG_RS12190	COG3391	amine dehydrogenase activity
TBMG_RS12200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TBMG_RS12215	COG0657	acetylesterase activity
TBMG_RS12245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TBMG_RS12245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TBMG_RS12270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBMG_RS12345	COG1271	oxidase subunit
TBMG_RS12350	COG1294	oxidase, subunit
TBMG_RS12355	COG4988	ABC transporter
TBMG_RS12360	COG1132	(ABC) transporter
TBMG_RS12365	COG0456	acetyltransferase
TBMG_RS12365	COG0454	-acetyltransferase
TBMG_RS12370	COG1946	Acyl-CoA thioesterase
TBMG_RS12425	COG0387	Pfam Sodium calcium exchanger
TBMG_RS12435	COG0107	imidazoleglycerol-phosphate synthase activity
TBMG_RS12440	COG0483	inositol monophosphate 1-phosphatase activity
TBMG_RS12500	COG1073	alpha beta
TBMG_RS12550	COG0791	NLP P60 protein
TBMG_RS12550	COG3883	PFAM NLP P60 protein
TBMG_RS12660	COG0300	oxidoreductase activity
TBMG_RS12715	COG2070	2-Nitropropane dioxygenase
TBMG_RS12745	COG3321	synthase
TBMG_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS12745	COG0604	alcohol dehydrogenase
TBMG_RS12820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBMG_RS12825	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
TBMG_RS12840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
TBMG_RS12860	COG4106	trans-aconitate 2-methyltransferase activity
TBMG_RS12870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TBMG_RS12900	COG3360	Dodecin
TBMG_RS12905	COG2226	methyltransferase
TBMG_RS12910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TBMG_RS12995	COG2304	oxidoreductase activity
TBMG_RS13005	COG0714	Associated with various cellular activities
TBMG_RS13015	COG3883	PFAM NLP P60 protein
TBMG_RS13015	COG0791	NLP P60 protein
TBMG_RS13025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TBMG_RS13030	COG1309	transcriptional regulator
TBMG_RS13040	COG0488	(ABC) transporter
TBMG_RS13050	COG3118	belongs to the thioredoxin family
TBMG_RS13070	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS13075	COG2151	metal-sulfur cluster biosynthetic enzyme
TBMG_RS13090	COG0396	ATPase activity
TBMG_RS13115	COG1131	(ABC) transporter
TBMG_RS13145	COG0657	acetylesterase activity
TBMG_RS13155	COG0657	acetylesterase activity
TBMG_RS13170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TBMG_RS13210	COG0657	acetylesterase activity
TBMG_RS13230	COG0149	triose-phosphate isomerase activity
TBMG_RS13255	COG1376	ErfK ybiS ycfS ynhG family protein
TBMG_RS13270	COG5651	PPE family
TBMG_RS13270	COG3391	amine dehydrogenase activity
TBMG_RS13285	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS13290	COG0657	acetylesterase activity
TBMG_RS13305	COG1481	regulation of sporulation
TBMG_RS13420	COG0657	acetylesterase activity
TBMG_RS13460	COG2072	flavoprotein involved in K transport
TBMG_RS13465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TBMG_RS13545	COG2226	methyltransferase
TBMG_RS13620	COG5651	PPE family
TBMG_RS13745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TBMG_RS13795	COG0058	SHG alpha-glucan phosphorylase activity
TBMG_RS13805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TBMG_RS13825	COG0346	lactoylglutathione lyase activity
TBMG_RS14190	COG0277	FAD linked oxidase domain protein
TBMG_RS14235	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBMG_RS14235	COG0567	Dehydrogenase, E1 component
TBMG_RS14240	COG2161	toxin-antitoxin pair type II binding
TBMG_RS14245	COG2026	Addiction module toxin, RelE StbE family
TBMG_RS14280	COG0598	Magnesium transport protein CorA
TBMG_RS14315	COG2239	Acts as a magnesium transporter
TBMG_RS14355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TBMG_RS14365	COG5662	AntiSigma factor
TBMG_RS14380	COG1309	transcriptional regulator
TBMG_RS14385	COG1131	(ABC) transporter
TBMG_RS14390	COG3559	Exporter of polyketide antibiotics
TBMG_RS14425	COG0519	Catalyzes the synthesis of GMP from XMP
TBMG_RS14450	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS14455	COG1611	Belongs to the LOG family
TBMG_RS14480	COG0477	Major facilitator Superfamily
TBMG_RS14485	COG3328	transposase activity
TBMG_RS14500	COG5651	PPE family
TBMG_RS14505	COG0657	acetylesterase activity
TBMG_RS14515	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS14530	COG0596	Alpha beta hydrolase
TBMG_RS14540	COG0506	proline dehydrogenase activity
TBMG_RS14545	COG1012	belongs to the aldehyde dehydrogenase family
TBMG_RS14560	COG5651	PPE family
TBMG_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS14575	COG0604	alcohol dehydrogenase
TBMG_RS14575	COG3321	synthase
TBMG_RS14590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TBMG_RS14600	COG1902	pentaerythritol trinitrate reductase activity
TBMG_RS14600	COG0446	pyridine nucleotide-disulphide oxidoreductase
TBMG_RS14650	COG1217	gtp-binding protein TYPA
TBMG_RS14665	COG1140	nitrate reductase beta subunit
TBMG_RS14710	COG3467	pyridoxamine 5'-phosphate
TBMG_RS14720	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
TBMG_RS14775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TBMG_RS14780	COG1024	Enoyl-CoA hydratase
TBMG_RS14785	COG1024	Enoyl-CoA hydratase
TBMG_RS14795	COG1755	Isoprenylcysteine carboxyl methyltransferase
TBMG_RS14815	COG0183	Belongs to the thiolase family
TBMG_RS14850	COG3800	Transcriptional regulator
TBMG_RS14850	COG1396	sequence-specific DNA binding
TBMG_RS14855	COG1403	HNH endonuclease
TBMG_RS14860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TBMG_RS14860	COG0574	Belongs to the PEP-utilizing enzyme family
TBMG_RS14875	COG0596	Alpha beta hydrolase
TBMG_RS14885	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TBMG_RS14940	COG0012	GTP binding
TBMG_RS14980	COG2272	Belongs to the type-B carboxylesterase lipase family
TBMG_RS15025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TBMG_RS15070	COG0657	acetylesterase activity
TBMG_RS15095	COG1331	Highly conserved protein containing a thioredoxin domain
TBMG_RS15135	COG0657	acetylesterase activity
TBMG_RS15140	COG2755	lipolytic protein G-D-S-L family
TBMG_RS15145	COG0183	Belongs to the thiolase family
TBMG_RS15225	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS15230	COG3391	amine dehydrogenase activity
TBMG_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS15300	COG3328	transposase activity
TBMG_RS15320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBMG_RS15340	COG0657	acetylesterase activity
TBMG_RS15375	COG0745	RESPONSE REGULATOR receiver
TBMG_RS15445	COG3956	TIGRFAM MazG family protein
TBMG_RS15490	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS15515	COG0084	hydrolase, TatD family'
TBMG_RS15530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TBMG_RS15565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBMG_RS15565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TBMG_RS15570	COG4106	trans-aconitate 2-methyltransferase activity
TBMG_RS15605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TBMG_RS15610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TBMG_RS15625	COG0142	geranyltranstransferase activity
TBMG_RS15635	COG0577	efflux transmembrane transporter activity
TBMG_RS15645	COG1970	mechanosensitive ion channel activity
TBMG_RS15650	COG0315	cyclic pyranopterin monophosphate synthase activity
TBMG_RS15650	COG0521	Mo-molybdopterin cofactor biosynthetic process
TBMG_RS15655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBMG_RS15660	COG2972	Histidine kinase
TBMG_RS15660	COG2205	protein histidine kinase activity
TBMG_RS15665	COG0745	RESPONSE REGULATOR receiver
TBMG_RS15670	COG3391	amine dehydrogenase activity
TBMG_RS15685	COG3391	amine dehydrogenase activity
TBMG_RS15695	COG0657	acetylesterase activity
TBMG_RS15710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBMG_RS15725	COG1024	Enoyl-CoA hydratase
TBMG_RS15830	COG0045	succinate-CoA ligase (ADP-forming) activity
TBMG_RS15870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TBMG_RS15990	COG3328	transposase activity
TBMG_RS16030	COG0183	Belongs to the thiolase family
TBMG_RS16255	COG1278	Cold shock
TBMG_RS16260	COG3304	Inner membrane component domain
TBMG_RS16285	COG0521	Mo-molybdopterin cofactor biosynthetic process
TBMG_RS16310	COG1024	Enoyl-CoA hydratase
TBMG_RS16310	COG1250	3-hydroxyacyl-CoA dehydrogenase
TBMG_RS16315	COG0183	Belongs to the thiolase family
TBMG_RS16335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TBMG_RS16370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TBMG_RS16380	COG2132	Multicopper oxidase
TBMG_RS16385	COG4585	Histidine kinase
TBMG_RS16395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TBMG_RS16410	COG0596	Alpha beta hydrolase
TBMG_RS16415	COG4106	trans-aconitate 2-methyltransferase activity
TBMG_RS16435	COG2963	transposase activity
TBMG_RS16440	COG2801	Transposase and inactivated derivatives
TBMG_RS16455	COG3328	transposase activity
TBMG_RS16500	COG3629	intracellular signal transduction
TBMG_RS16525	COG2801	Transposase and inactivated derivatives
TBMG_RS16560	COG5651	PPE family
TBMG_RS16575	COG0483	inositol monophosphate 1-phosphatase activity
TBMG_RS16590	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS16595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS16595	COG3321	synthase
TBMG_RS16595	COG4221	oxidoreductase activity
TBMG_RS16595	COG0604	alcohol dehydrogenase
TBMG_RS16655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBMG_RS16710	COG0714	Associated with various cellular activities
TBMG_RS16755	COG1309	transcriptional regulator
TBMG_RS16765	COG0154	amidase activity
TBMG_RS16780	COG0748	coenzyme F420 binding
TBMG_RS16805	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
TBMG_RS16810	COG1396	sequence-specific DNA binding
TBMG_RS16840	COG2826	transposase and inactivated derivatives, IS30 family
TBMG_RS16860	COG1615	UPF0182 protein
TBMG_RS16885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TBMG_RS16905	COG2816	NAD+ diphosphatase activity
TBMG_RS16915	COG0210	DNA helicase
TBMG_RS16930	COG0596	Alpha beta hydrolase
TBMG_RS16935	COG3695	enzyme binding
TBMG_RS16975	COG0513	Belongs to the DEAD box helicase family
TBMG_RS16990	COG0406	alpha-ribazole phosphatase activity
TBMG_RS17010	COG1597	lipid kinase activity
TBMG_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS17055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TBMG_RS17065	COG2135	peptidase activity
TBMG_RS17070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TBMG_RS17075	COG1162	GTPase activity
TBMG_RS17095	COG2326	polyphosphate kinase activity
TBMG_RS17110	COG4651	solute:proton antiporter activity
TBMG_RS17110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TBMG_RS17120	COG2020	methyltransferase activity
TBMG_RS17135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TBMG_RS17190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TBMG_RS17195	COG0531	amino acid
TBMG_RS17200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TBMG_RS17205	COG1482	cell wall glycoprotein biosynthetic process
TBMG_RS17215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TBMG_RS17265	COG1316	TRANSCRIPTIONal
TBMG_RS17290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TBMG_RS17295	COG0659	secondary active sulfate transmembrane transporter activity
TBMG_RS17330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBMG_RS17340	COG0424	maF-like protein
TBMG_RS17355	COG4770	biotin carboxylase activity
TBMG_RS17385	COG1522	sequence-specific DNA binding
TBMG_RS17395	COG1012	belongs to the aldehyde dehydrogenase family
TBMG_RS17405	COG1309	transcriptional regulator
TBMG_RS17410	COG1201	RNA secondary structure unwinding
TBMG_RS17425	COG3408	Glycogen debranching enzyme
TBMG_RS17425	COG3119	arylsulfatase activity
TBMG_RS17430	COG0564	pseudouridine synthase activity
TBMG_RS17455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TBMG_RS17455	COG1473	amidohydrolase
TBMG_RS17470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TBMG_RS17480	COG3511	phospholipase C
TBMG_RS17515	COG2009	succinate dehydrogenase
TBMG_RS17525	COG1053	succinate dehydrogenase
TBMG_RS17530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TBMG_RS17560	COG2154	pterin-4-alpha-carbinolamine dehydratase
TBMG_RS17565	COG2801	Transposase and inactivated derivatives
TBMG_RS17570	COG2963	transposase activity
TBMG_RS17575	COG1595	DNA-templated transcription, initiation
TBMG_RS17580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TBMG_RS17585	COG1686	Belongs to the peptidase S11 family
TBMG_RS17590	COG2814	Major facilitator Superfamily
TBMG_RS17595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TBMG_RS17605	COG0789	Transcriptional regulator
TBMG_RS17630	COG2873	o-acetylhomoserine
TBMG_RS17645	COG5651	PPE family
TBMG_RS17655	COG0657	acetylesterase activity
TBMG_RS17665	COG5651	PPE family
TBMG_RS17665	COG5651	PPE family
TBMG_RS17685	COG5651	PPE family
TBMG_RS17685	COG5651	PPE family
TBMG_RS17685	COG5651	PPE family
TBMG_RS17695	COG0277	FAD linked oxidase domain protein
TBMG_RS17715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TBMG_RS17735	COG1716	ATPase activity
TBMG_RS17735	COG0842	Transport permease protein
TBMG_RS17735	COG1131	(ABC) transporter
TBMG_RS17740	COG1357	PFAM Pentapeptide repeats (8 copies)
TBMG_RS17755	COG2018	Roadblock/LC7 domain
TBMG_RS17765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TBMG_RS17790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS17800	COG1024	Enoyl-CoA hydratase
TBMG_RS17820	COG1657	PFAM Prenyltransferase squalene oxidase
TBMG_RS17830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TBMG_RS17845	COG0142	geranyltranstransferase activity
TBMG_RS17850	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
TBMG_RS17875	COG2030	dehydratase
TBMG_RS17880	COG0406	alpha-ribazole phosphatase activity
TBMG_RS17890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS18035	COG0456	acetyltransferase
TBMG_RS18065	COG2801	Transposase and inactivated derivatives
TBMG_RS18070	COG3328	transposase activity
TBMG_RS18075	COG0076	glutamate decarboxylase activity
TBMG_RS18135	COG4842	Belongs to the WXG100 family
TBMG_RS18140	COG4842	Belongs to the WXG100 family
TBMG_RS18150	COG1674	ftsk spoiiie
TBMG_RS18160	COG1404	Belongs to the peptidase S8 family
TBMG_RS18210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TBMG_RS18225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TBMG_RS18250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TBMG_RS18255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TBMG_RS18260	COG0028	Belongs to the TPP enzyme family
TBMG_RS18280	COG0477	Major facilitator Superfamily
TBMG_RS18290	COG5651	PPE family
TBMG_RS18295	COG1752	Esterase of the alpha-beta hydrolase superfamily
TBMG_RS18300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS18320	COG1316	TRANSCRIPTIONal
TBMG_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS18330	COG2259	Doxx family
TBMG_RS18335	COG0657	acetylesterase activity
TBMG_RS18340	COG1695	Transcriptional regulator
TBMG_RS18350	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TBMG_RS18375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBMG_RS18400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBMG_RS18405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBMG_RS18420	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18425	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18430	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS18435	COG0657	acetylesterase activity
TBMG_RS18440	COG0657	acetylesterase activity
TBMG_RS18445	COG0028	Belongs to the TPP enzyme family
TBMG_RS18455	COG0657	acetylesterase activity
TBMG_RS18465	COG0657	acetylesterase activity
TBMG_RS18475	COG1024	Enoyl-CoA hydratase
TBMG_RS18485	COG2124	cytochrome p450
TBMG_RS18495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBMG_RS18505	COG0183	Belongs to the thiolase family
TBMG_RS18510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TBMG_RS18525	COG4638	Rieske (2fe-2S)
TBMG_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS18580	COG3971	2-oxopent-4-enoate hydratase activity
TBMG_RS18585	COG1053	succinate dehydrogenase
TBMG_RS18590	COG2030	dehydratase
TBMG_RS18610	COG2030	dehydratase
TBMG_RS18615	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18620	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18630	COG0183	Belongs to the thiolase family
TBMG_RS18640	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS18650	COG1024	Enoyl-CoA hydratase
TBMG_RS18670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TBMG_RS18680	COG0183	Belongs to the thiolase family
TBMG_RS18700	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18705	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS18710	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18715	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18720	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18725	COG0436	Aminotransferase
TBMG_RS18770	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS18775	COG1309	transcriptional regulator
TBMG_RS18780	COG1609	Transcriptional regulator
TBMG_RS18800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TBMG_RS18835	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TBMG_RS18855	COG0657	acetylesterase activity
TBMG_RS18875	COG0739	heme binding
TBMG_RS18955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBMG_RS18985	COG2267	carboxylic ester hydrolase activity
TBMG_RS19035	COG2027	D-alanyl-D-alanine carboxypeptidase
TBMG_RS19095	COG2801	Transposase and inactivated derivatives
TBMG_RS19100	COG2963	transposase activity
TBMG_RS19110	COG3328	transposase activity
TBMG_RS19115	COG2184	nucleotidyltransferase activity
TBMG_RS19135	COG0470	DNA polymerase III
TBMG_RS19160	COG1205	dead DEAH box helicase
TBMG_RS19160	COG1111	helicase
TBMG_RS19165	COG0657	acetylesterase activity
TBMG_RS19180	COG0657	acetylesterase activity
TBMG_RS19230	COG4172	Belongs to the ABC transporter superfamily
TBMG_RS19235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TBMG_RS19240	COG0601	transmembrane transport
TBMG_RS19280	COG0494	nUDIX hydrolase
TBMG_RS19305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBMG_RS19340	COG1408	metallophosphoesterase
TBMG_RS19345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TBMG_RS19390	COG0714	Associated with various cellular activities
TBMG_RS19410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TBMG_RS19445	COG0121	glutamine amidotransferase
TBMG_RS19450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TBMG_RS19500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TBMG_RS19525	COG0860	N-Acetylmuramoyl-L-alanine amidase
TBMG_RS19540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TBMG_RS19550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TBMG_RS19575	COG1063	alcohol dehydrogenase
TBMG_RS19580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TBMG_RS19580	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
TBMG_RS19585	COG0477	Major facilitator Superfamily
TBMG_RS19590	COG2226	methyltransferase
TBMG_RS19600	COG1793	dna ligase
TBMG_RS19655	COG2072	flavoprotein involved in K transport
TBMG_RS19665	COG0640	Transcriptional regulator
TBMG_RS19690	COG1569	PIN domain
TBMG_RS19695	COG3311	Transcriptional regulator
TBMG_RS19710	COG0590	tRNA wobble adenosine to inosine editing
TBMG_RS19720	COG0287	Prephenate dehydrogenase
TBMG_RS19740	COG1125	glycine betaine transport
TBMG_RS19740	COG0517	IMP dehydrogenase activity
TBMG_RS19750	COG5416	Lipopolysaccharide assembly protein A domain
TBMG_RS19760	COG2015	COG2015, Alkyl sulfatase and related hydrolases
TBMG_RS19770	COG2205	protein histidine kinase activity
TBMG_RS19775	COG0745	RESPONSE REGULATOR receiver
TBMG_RS19780	COG0739	heme binding
TBMG_RS19830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TBMG_RS19900	COG1088	dTDP-glucose 4,6-dehydratase activity
TBMG_RS19945	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TBMG_RS19960	COG1234	tRNA 3'-trailer cleavage
TBMG_RS19965	COG1960	acyl-CoA dehydrogenase activity
TBMG_RS19975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TBMG_RS19980	COG3321	synthase
TBMG_RS19980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TBMG_RS19980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TBMG_RS19985	COG0318	PFAM AMP-dependent synthetase and ligase
TBMG_RS19990	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
TBMG_RS20005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TBMG_RS20020	COG1216	Glycosyl transferase, family 2
TBMG_RS20040	COG0657	acetylesterase activity
TBMG_RS20050	COG0561	phosphatase activity
TBMG_RS20085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TBMG_RS20095	COG5651	PPE family
TBMG_RS20100	COG1511	domain protein
TBMG_RS20100	COG2409	Drug exporters of the RND superfamily
TBMG_RS20110	COG3321	synthase
TBMG_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
TBMG_RS20110	COG0604	alcohol dehydrogenase
TBMG_RS20155	COG2207	Transcriptional regulator
TBMG_RS20190	COG1316	TRANSCRIPTIONal
TBMG_RS20235	COG2119	membrane
TBMG_RS20275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TBMG_RS20275	COG1796	DNA polymerase
TBMG_RS20290	COG0067	glutamate synthase
TBMG_RS20290	COG0069	glutamate synthase activity
TBMG_RS20290	COG0070	glutamate synthase
TBMG_RS20390	COG4932	domain protein
TBMG_RS20410	COG1404	Belongs to the peptidase S8 family
TBMG_RS20415	COG0464	growth
TBMG_RS20425	COG1404	Belongs to the peptidase S8 family
TBMG_RS20455	COG5651	PPE family
TBMG_RS20465	COG1674	ftsk spoiiie
TBMG_RS20550	COG1595	DNA-templated transcription, initiation
TBMG_RS20570	COG0860	N-Acetylmuramoyl-L-alanine amidase
TBMG_RS20570	COG3409	Peptidoglycan-binding domain 1 protein
TBMG_RS20585	COG1192	Involved in chromosome partitioning
TBMG_RS20605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TBMG_RS20615	COG0230	Belongs to the bacterial ribosomal protein bL34 family