locus-tag	class	description
CP464_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP464_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP464_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP464_RS00090	COG0515	serine threonine protein kinase
CP464_RS00115	COG1716	ATPase activity
CP464_RS00190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP464_RS00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS00250	COG0596	Alpha beta hydrolase
CP464_RS00250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP464_RS00255	COG1260	myo-inositol-1-phosphate synthase
CP464_RS00275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP464_RS00345	COG0277	FAD linked oxidase domain protein
CP464_RS00375	COG1309	transcriptional regulator
CP464_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS00395	COG3344	reverse transcriptase
CP464_RS00410	COG1228	amidohydrolase
CP464_RS00430	COG1309	transcriptional regulator
CP464_RS00460	COG3260	NADH ubiquinone oxidoreductase 20
CP464_RS00470	COG0650	Formate hydrogenlyase subunit 4
CP464_RS00480	COG0651	ATP synthesis coupled electron transport
CP464_RS00485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CP464_RS00485	COG3261	NADH dehydrogenase
CP464_RS00530	COG1403	HNH endonuclease
CP464_RS00560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS00600	COG0657	acetylesterase activity
CP464_RS00610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP464_RS00610	COG2755	lipolytic protein G-D-S-L family
CP464_RS00640	COG1376	ErfK ybiS ycfS ynhG family protein
CP464_RS00645	COG0583	DNA-binding transcription factor activity
CP464_RS00650	COG0028	Belongs to the TPP enzyme family
CP464_RS00685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP464_RS00720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS00775	COG0038	chloride channel
CP464_RS00780	COG1309	transcriptional regulator
CP464_RS00795	COG1012	belongs to the aldehyde dehydrogenase family
CP464_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS00805	COG0604	alcohol dehydrogenase
CP464_RS00805	COG3321	synthase
CP464_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS00830	COG3391	amine dehydrogenase activity
CP464_RS00835	COG2365	Tyrosine phosphatase family
CP464_RS00870	COG1309	transcriptional regulator
CP464_RS00875	COG0657	acetylesterase activity
CP464_RS00875	COG5651	PPE family
CP464_RS00880	COG0657	acetylesterase activity
CP464_RS00880	COG5651	PPE family
CP464_RS00885	COG0277	FAD linked oxidase domain protein
CP464_RS00890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CP464_RS00920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP464_RS00925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP464_RS00950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP464_RS01000	COG2267	carboxylic ester hydrolase activity
CP464_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
CP464_RS01040	COG1937	Protein conserved in bacteria
CP464_RS01045	COG2814	Major facilitator Superfamily
CP464_RS01050	COG1376	ErfK ybiS ycfS ynhG family protein
CP464_RS01060	COG1132	(ABC) transporter
CP464_RS01075	COG0243	molybdopterin cofactor binding
CP464_RS01080	COG3590	peptidase
CP464_RS01120	COG2409	Drug exporters of the RND superfamily
CP464_RS01175	COG0657	acetylesterase activity
CP464_RS01180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP464_RS01190	COG0657	acetylesterase activity
CP464_RS01200	COG1024	Enoyl-CoA hydratase
CP464_RS01210	COG0500	methyltransferase
CP464_RS01215	COG0297	glycogen (starch) synthase activity
CP464_RS01235	COG1487	ribonuclease activity
CP464_RS01275	COG4981	capsule polysaccharide biosynthetic process
CP464_RS01285	COG1472	Belongs to the glycosyl hydrolase 3 family
CP464_RS01305	COG2030	dehydratase
CP464_RS01315	COG0183	Belongs to the thiolase family
CP464_RS01320	COG1960	acyl-CoA dehydrogenase activity
CP464_RS01340	COG1053	succinate dehydrogenase
CP464_RS01360	COG2146	nitrite reductase [NAD(P)H] activity
CP464_RS01360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP464_RS01380	COG5651	PPE family
CP464_RS01420	COG1984	allophanate hydrolase subunit 2
CP464_RS01440	COG2223	nitrite transmembrane transporter activity
CP464_RS01445	COG2161	toxin-antitoxin pair type II binding
CP464_RS01455	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS01460	COG1960	acyl-CoA dehydrogenase activity
CP464_RS01475	COG0346	lactoylglutathione lyase activity
CP464_RS01505	COG3391	amine dehydrogenase activity
CP464_RS01505	COG3391	amine dehydrogenase activity
CP464_RS01515	COG5651	PPE family
CP464_RS01570	COG1404	Belongs to the peptidase S8 family
CP464_RS01595	COG1368	sulfuric ester hydrolase activity
CP464_RS01600	COG3391	amine dehydrogenase activity
CP464_RS01640	COG0778	Nitroreductase
CP464_RS01650	COG0671	phosphoesterase, PA-phosphatase related
CP464_RS01720	COG0717	Belongs to the dCTP deaminase family
CP464_RS01725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP464_RS01730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP464_RS01745	COG2226	methyltransferase
CP464_RS01760	COG2226	methyltransferase
CP464_RS01770	COG1252	NADH dehydrogenase
CP464_RS01810	COG0247	lactate metabolic process
CP464_RS01810	COG2181	nitrate reductase activity
CP464_RS01885	COG0789	Transcriptional regulator
CP464_RS01910	COG1994	Peptidase M50
CP464_RS01925	COG2239	Acts as a magnesium transporter
CP464_RS01970	COG0746	molybdenum cofactor guanylyltransferase activity
CP464_RS02010	COG3360	Dodecin
CP464_RS02060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CP464_RS02075	COG1252	NADH dehydrogenase
CP464_RS02080	COG1403	HNH endonuclease
CP464_RS02125	COG1960	acyl-CoA dehydrogenase activity
CP464_RS02150	COG0604	alcohol dehydrogenase
CP464_RS02150	COG3321	synthase
CP464_RS02150	COG0604	alcohol dehydrogenase
CP464_RS02150	COG3321	synthase
CP464_RS02155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP464_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP464_RS02220	COG2234	aminopeptidase activity
CP464_RS02255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP464_RS02305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP464_RS02310	COG1183	phosphatidylcholine synthase activity
CP464_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS02350	COG5343	regulation of RNA biosynthetic process
CP464_RS02365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS02415	COG1024	Enoyl-CoA hydratase
CP464_RS02420	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS02430	COG1505	serine-type exopeptidase activity
CP464_RS02490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS02515	COG2733	membrane
CP464_RS02725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP464_RS02725	COG1648	precorrin-2 dehydrogenase activity
CP464_RS02750	COG1366	Belongs to the anti-sigma-factor antagonist family
CP464_RS02755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP464_RS02755	COG2755	lipolytic protein G-D-S-L family
CP464_RS02760	COG2755	lipolytic protein G-D-S-L family
CP464_RS02785	COG1113	amino acid transport
CP464_RS02800	COG0406	alpha-ribazole phosphatase activity
CP464_RS02810	COG0785	Cytochrome C biogenesis protein
CP464_RS02820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP464_RS02845	COG3391	amine dehydrogenase activity
CP464_RS02860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP464_RS02865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP464_RS02910	COG0306	phosphate transporter
CP464_RS02920	COG4221	oxidoreductase activity
CP464_RS02940	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS02945	COG1228	amidohydrolase
CP464_RS02995	COG0142	geranyltranstransferase activity
CP464_RS03010	COG2072	flavoprotein involved in K transport
CP464_RS03025	COG2345	Transcriptional regulator
CP464_RS03040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP464_RS03110	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
CP464_RS03120	COG3537	Alpha-1,2-mannosidase
CP464_RS03140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP464_RS03165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP464_RS03175	COG1487	ribonuclease activity
CP464_RS03195	COG2002	toxin-antitoxin pair type II binding
CP464_RS03205	COG2972	Histidine kinase
CP464_RS03210	COG0745	RESPONSE REGULATOR receiver
CP464_RS03280	COG0653	protein targeting
CP464_RS03315	COG1085	galactose-1-phosphate uridylyltransferase
CP464_RS03320	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP464_RS03360	COG1487	ribonuclease activity
CP464_RS03380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CP464_RS03425	COG2030	dehydratase
CP464_RS03455	COG0081	regulation of translation
CP464_RS03460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS03465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS03470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS03475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS03515	COG1309	transcriptional regulator
CP464_RS03595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP464_RS03620	COG1960	acyl-CoA dehydrogenase activity
CP464_RS03635	COG1024	Enoyl-CoA hydratase
CP464_RS03650	COG1510	regulation of RNA biosynthetic process
CP464_RS03665	COG1309	transcriptional regulator
CP464_RS03730	COG0535	radical SAM domain protein
CP464_RS03845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP464_RS03900	COG0200	Binds to the 23S rRNA
CP464_RS03905	COG0616	signal peptide processing
CP464_RS03920	COG0235	Class ii aldolase
CP464_RS03925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP464_RS04010	COG0657	acetylesterase activity
CP464_RS04085	COG0406	alpha-ribazole phosphatase activity
CP464_RS04110	COG0745	RESPONSE REGULATOR receiver
CP464_RS04115	COG2205	protein histidine kinase activity
CP464_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS04210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP464_RS04240	COG0477	Major facilitator Superfamily
CP464_RS04250	COG3573	Dehydrogenase
CP464_RS04265	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP464_RS04285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS04290	COG2188	Transcriptional regulator
CP464_RS04295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CP464_RS04300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP464_RS04315	COG3547	Transposase (IS116 IS110 IS902 family)
CP464_RS04325	COG2837	iron assimilation
CP464_RS04375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP464_RS04425	COG0745	RESPONSE REGULATOR receiver
CP464_RS04470	COG0640	Transcriptional regulator
CP464_RS04475	COG0590	tRNA wobble adenosine to inosine editing
CP464_RS04515	COG3391	amine dehydrogenase activity
CP464_RS04565	COG4106	trans-aconitate 2-methyltransferase activity
CP464_RS04570	COG0596	Alpha beta hydrolase
CP464_RS04590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CP464_RS04600	COG4585	Histidine kinase
CP464_RS04605	COG2132	Multicopper oxidase
CP464_RS04615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP464_RS04655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP464_RS04675	COG0183	Belongs to the thiolase family
CP464_RS04680	COG1024	Enoyl-CoA hydratase
CP464_RS04680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP464_RS04705	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP464_RS04730	COG3304	Inner membrane component domain
CP464_RS04735	COG1278	Cold shock
CP464_RS04970	COG0183	Belongs to the thiolase family
CP464_RS05010	COG3328	transposase activity
CP464_RS05060	COG0581	inorganic phosphate transmembrane transporter activity
CP464_RS05100	COG1793	dna ligase
CP464_RS05100	COG3285	dna ligase
CP464_RS05130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP464_RS05145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP464_RS05170	COG0739	heme binding
CP464_RS05175	COG0045	succinate-CoA ligase (ADP-forming) activity
CP464_RS05285	COG1024	Enoyl-CoA hydratase
CP464_RS05300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP464_RS05315	COG0657	acetylesterase activity
CP464_RS05325	COG3391	amine dehydrogenase activity
CP464_RS05340	COG3391	amine dehydrogenase activity
CP464_RS05345	COG0745	RESPONSE REGULATOR receiver
CP464_RS05350	COG2205	protein histidine kinase activity
CP464_RS05350	COG2972	Histidine kinase
CP464_RS05355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP464_RS05360	COG0315	cyclic pyranopterin monophosphate synthase activity
CP464_RS05360	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP464_RS05365	COG1970	mechanosensitive ion channel activity
CP464_RS05375	COG0577	efflux transmembrane transporter activity
CP464_RS05385	COG0142	geranyltranstransferase activity
CP464_RS05400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP464_RS05405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP464_RS05445	COG4106	trans-aconitate 2-methyltransferase activity
CP464_RS05450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP464_RS05450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP464_RS05485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP464_RS05500	COG0084	hydrolase, TatD family'
CP464_RS05530	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS05575	COG3956	TIGRFAM MazG family protein
CP464_RS05645	COG2205	protein histidine kinase activity
CP464_RS05650	COG0745	RESPONSE REGULATOR receiver
CP464_RS05675	COG0657	acetylesterase activity
CP464_RS05700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP464_RS05720	COG3328	transposase activity
CP464_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS05790	COG3391	amine dehydrogenase activity
CP464_RS05795	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS05875	COG0183	Belongs to the thiolase family
CP464_RS05880	COG2755	lipolytic protein G-D-S-L family
CP464_RS05885	COG0657	acetylesterase activity
CP464_RS05925	COG1331	Highly conserved protein containing a thioredoxin domain
CP464_RS05955	COG0657	acetylesterase activity
CP464_RS06000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP464_RS06080	COG0012	GTP binding
CP464_RS06130	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP464_RS06140	COG0596	Alpha beta hydrolase
CP464_RS06155	COG0574	Belongs to the PEP-utilizing enzyme family
CP464_RS06155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP464_RS06160	COG1403	HNH endonuclease
CP464_RS06165	COG1396	sequence-specific DNA binding
CP464_RS06165	COG3800	Transcriptional regulator
CP464_RS06170	COG2079	MmgE PrpD family protein
CP464_RS06200	COG0183	Belongs to the thiolase family
CP464_RS06220	COG1755	Isoprenylcysteine carboxyl methyltransferase
CP464_RS06235	COG1024	Enoyl-CoA hydratase
CP464_RS06240	COG1024	Enoyl-CoA hydratase
CP464_RS06245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP464_RS06260	COG2409	Drug exporters of the RND superfamily
CP464_RS06265	COG2409	Drug exporters of the RND superfamily
CP464_RS06310	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP464_RS06320	COG3467	pyridoxamine 5'-phosphate
CP464_RS06370	COG1140	nitrate reductase beta subunit
CP464_RS06385	COG1217	gtp-binding protein TYPA
CP464_RS06435	COG1902	pentaerythritol trinitrate reductase activity
CP464_RS06435	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP464_RS06445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CP464_RS06460	COG3321	synthase
CP464_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS06460	COG0604	alcohol dehydrogenase
CP464_RS06475	COG5651	PPE family
CP464_RS06485	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CP464_RS06485	COG2508	Transcriptional regulator
CP464_RS06490	COG1012	belongs to the aldehyde dehydrogenase family
CP464_RS06495	COG0506	proline dehydrogenase activity
CP464_RS06505	COG0596	Alpha beta hydrolase
CP464_RS06520	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS06535	COG0657	acetylesterase activity
CP464_RS06540	COG5651	PPE family
CP464_RS06545	COG4842	Belongs to the WXG100 family
CP464_RS06555	COG3328	transposase activity
CP464_RS06565	COG0477	Major facilitator Superfamily
CP464_RS06590	COG1611	Belongs to the LOG family
CP464_RS06595	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS06615	COG0519	Catalyzes the synthesis of GMP from XMP
CP464_RS06650	COG3559	Exporter of polyketide antibiotics
CP464_RS06655	COG1131	(ABC) transporter
CP464_RS06660	COG1309	transcriptional regulator
CP464_RS06680	COG5662	AntiSigma factor
CP464_RS06685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP464_RS06690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP464_RS06735	COG2239	Acts as a magnesium transporter
CP464_RS06770	COG0598	Magnesium transport protein CorA
CP464_RS06810	COG2026	Addiction module toxin, RelE StbE family
CP464_RS06815	COG2161	toxin-antitoxin pair type II binding
CP464_RS06820	COG0567	Dehydrogenase, E1 component
CP464_RS06820	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP464_RS06865	COG0277	FAD linked oxidase domain protein
CP464_RS07240	COG0346	lactoylglutathione lyase activity
CP464_RS07260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP464_RS07270	COG0058	SHG alpha-glucan phosphorylase activity
CP464_RS07320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP464_RS07455	COG5651	PPE family
CP464_RS07535	COG2226	methyltransferase
CP464_RS07615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP464_RS07620	COG2072	flavoprotein involved in K transport
CP464_RS07625	COG2124	cytochrome p450
CP464_RS07655	COG0657	acetylesterase activity
CP464_RS07785	COG0657	acetylesterase activity
CP464_RS07790	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS07805	COG3391	amine dehydrogenase activity
CP464_RS07805	COG5651	PPE family
CP464_RS07820	COG1376	ErfK ybiS ycfS ynhG family protein
CP464_RS07850	COG0149	triose-phosphate isomerase activity
CP464_RS07880	COG0657	acetylesterase activity
CP464_RS07925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP464_RS07930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP464_RS07940	COG0657	acetylesterase activity
CP464_RS07950	COG0657	acetylesterase activity
CP464_RS07980	COG1131	(ABC) transporter
CP464_RS08005	COG0396	ATPase activity
CP464_RS08020	COG2151	metal-sulfur cluster biosynthetic enzyme
CP464_RS08025	COG1960	acyl-CoA dehydrogenase activity
CP464_RS08045	COG3118	belongs to the thioredoxin family
CP464_RS08055	COG0488	(ABC) transporter
CP464_RS08065	COG1309	transcriptional regulator
CP464_RS08070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP464_RS08080	COG0791	NLP P60 protein
CP464_RS08080	COG3883	PFAM NLP P60 protein
CP464_RS08090	COG0714	Associated with various cellular activities
CP464_RS08100	COG2304	oxidoreductase activity
CP464_RS08190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP464_RS08195	COG2226	methyltransferase
CP464_RS08200	COG3360	Dodecin
CP464_RS08220	COG1621	beta-fructofuranosidase activity
CP464_RS08235	COG4106	trans-aconitate 2-methyltransferase activity
CP464_RS08255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP464_RS08275	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP464_RS08280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP464_RS08360	COG3321	synthase
CP464_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS08360	COG0604	alcohol dehydrogenase
CP464_RS08390	COG2070	2-Nitropropane dioxygenase
CP464_RS08445	COG0300	oxidoreductase activity
CP464_RS08560	COG3883	PFAM NLP P60 protein
CP464_RS08560	COG0791	NLP P60 protein
CP464_RS08680	COG1403	HNH endonuclease
CP464_RS08700	COG1073	alpha beta
CP464_RS08760	COG0483	inositol monophosphate 1-phosphatase activity
CP464_RS08765	COG0107	imidazoleglycerol-phosphate synthase activity
CP464_RS08775	COG0387	Pfam Sodium calcium exchanger
CP464_RS08835	COG1946	Acyl-CoA thioesterase
CP464_RS08840	COG0456	acetyltransferase
CP464_RS08840	COG0454	-acetyltransferase
CP464_RS08845	COG1132	(ABC) transporter
CP464_RS08850	COG4988	ABC transporter
CP464_RS08855	COG1294	oxidase, subunit
CP464_RS08860	COG1271	oxidase subunit
CP464_RS08945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP464_RS08995	COG0657	acetylesterase activity
CP464_RS09010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP464_RS09020	COG3391	amine dehydrogenase activity
CP464_RS09070	COG0604	alcohol dehydrogenase
CP464_RS09070	COG3321	synthase
CP464_RS09075	COG0604	alcohol dehydrogenase
CP464_RS09075	COG3321	synthase
CP464_RS09080	COG0604	alcohol dehydrogenase
CP464_RS09080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS09080	COG3321	synthase
CP464_RS09080	COG4221	oxidoreductase activity
CP464_RS09085	COG3321	synthase
CP464_RS09085	COG0604	alcohol dehydrogenase
CP464_RS09085	COG3321	synthase
CP464_RS09085	COG0604	alcohol dehydrogenase
CP464_RS09100	COG0488	(ABC) transporter
CP464_RS09155	COG1960	acyl-CoA dehydrogenase activity
CP464_RS09160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CP464_RS09180	COG2835	tetraacyldisaccharide 4'-kinase activity
CP464_RS09220	COG0647	UMP catabolic process
CP464_RS09260	COG0494	nUDIX hydrolase
CP464_RS09275	COG4122	O-methyltransferase activity
CP464_RS09280	COG1113	amino acid transport
CP464_RS09285	COG5651	PPE family
CP464_RS09300	COG0659	secondary active sulfate transmembrane transporter activity
CP464_RS09310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP464_RS09315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP464_RS09355	COG3246	L-lysine catabolic process to acetate
CP464_RS09505	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP464_RS09515	COG0842	Transport permease protein
CP464_RS09515	COG1131	(ABC) transporter
CP464_RS09515	COG1716	ATPase activity
CP464_RS09530	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS09545	COG5263	repeat protein
CP464_RS09545	COG5651	PPE family
CP464_RS09575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS09615	COG1937	Protein conserved in bacteria
CP464_RS09715	COG5651	PPE family
CP464_RS09725	COG5651	PPE family
CP464_RS09735	COG5651	PPE family
CP464_RS09765	COG1404	Belongs to the peptidase S8 family
CP464_RS09785	COG5651	PPE family
CP464_RS09805	COG0657	acetylesterase activity
CP464_RS09820	COG0657	acetylesterase activity
CP464_RS09835	COG5651	PPE family
CP464_RS09845	COG1285	pathogenesis
CP464_RS09925	COG0509	glycine decarboxylation via glycine cleavage system
CP464_RS09950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP464_RS09950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP464_RS10000	COG1253	flavin adenine dinucleotide binding
CP464_RS10005	COG1253	flavin adenine dinucleotide binding
CP464_RS10015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP464_RS10050	COG0830	nickel cation binding
CP464_RS10070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS10120	COG4221	oxidoreductase activity
CP464_RS10125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP464_RS10135	COG0183	Belongs to the thiolase family
CP464_RS10200	COG0174	glutamine synthetase
CP464_RS10220	COG0300	oxidoreductase activity
CP464_RS10230	COG1652	LysM domain
CP464_RS10240	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP464_RS10265	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP464_RS10270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP464_RS10295	COG2070	2-Nitropropane dioxygenase
CP464_RS10315	COG1490	D-aminoacyl-tRNA deacylase activity
CP464_RS10325	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP464_RS10345	COG1950	PFAM Membrane protein of
CP464_RS10350	COG1366	Belongs to the anti-sigma-factor antagonist family
CP464_RS10370	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP464_RS10405	COG2224	Isocitrate lyase
CP464_RS10415	COG5651	PPE family
CP464_RS10415	COG5263	repeat protein
CP464_RS10425	COG5263	repeat protein
CP464_RS10425	COG5651	PPE family
CP464_RS10445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP464_RS10450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP464_RS10460	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS10490	COG4977	sequence-specific DNA binding
CP464_RS10505	COG1960	acyl-CoA dehydrogenase activity
CP464_RS10510	COG1024	Enoyl-CoA hydratase
CP464_RS10525	COG0543	2 iron, 2 sulfur cluster binding
CP464_RS10525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP464_RS10530	COG0596	Alpha beta hydrolase
CP464_RS10540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP464_RS10540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP464_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS10550	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS10560	COG0653	protein targeting
CP464_RS10605	COG4691	Plasmid stability protein
CP464_RS10665	COG1309	transcriptional regulator
CP464_RS10710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP464_RS10790	COG1872	DUF167
CP464_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS11000	COG2442	InterPro IPR007367
CP464_RS11015	COG1396	sequence-specific DNA binding
CP464_RS11020	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CP464_RS11085	COG0640	Transcriptional regulator
CP464_RS11100	COG1752	Esterase of the alpha-beta hydrolase superfamily
CP464_RS11105	COG3842	ATPase activity
CP464_RS11110	COG0395	ABC-type sugar transport system, permease component
CP464_RS11115	COG1175	transmembrane transport
CP464_RS11130	COG1335	isochorismatase
CP464_RS11155	COG3321	synthase
CP464_RS11155	COG0604	alcohol dehydrogenase
CP464_RS11235	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS11260	COG2367	Beta-lactamase
CP464_RS11280	COG2241	protein methyltransferase activity
CP464_RS11280	COG2242	protein methyltransferase activity
CP464_RS11285	COG0300	oxidoreductase activity
CP464_RS11320	COG1511	domain protein
CP464_RS11355	COG2801	Transposase and inactivated derivatives
CP464_RS11370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP464_RS11420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP464_RS11425	COG4279	zinc finger
CP464_RS11430	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CP464_RS11440	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP464_RS11465	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP464_RS11535	COG5651	PPE family
CP464_RS11540	COG0646	methionine synthase
CP464_RS11540	COG1410	methionine synthase
CP464_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS11620	COG0167	dihydroorotate dehydrogenase activity
CP464_RS11630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP464_RS11685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP464_RS11700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP464_RS11750	COG0768	penicillin binding
CP464_RS11800	COG0142	geranyltranstransferase activity
CP464_RS11830	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP464_RS11860	COG0003	Pfam Anion-transporting ATPase
CP464_RS11875	COG1022	Amp-dependent synthetase and ligase
CP464_RS11955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP464_RS11985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP464_RS12010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP464_RS12030	COG0321	lipoyl(octanoyl) transferase activity
CP464_RS12085	COG3025	triphosphatase activity
CP464_RS12085	COG5607	PFAM CHAD domain containing protein
CP464_RS12120	COG3744	PilT protein domain protein
CP464_RS12145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP464_RS12290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP464_RS12295	COG4221	oxidoreductase activity
CP464_RS12365	COG0584	glycerophosphoryl diester phosphodiesterase
CP464_RS12395	COG0657	acetylesterase activity
CP464_RS12525	COG1073	alpha beta
CP464_RS12550	COG2442	InterPro IPR007367
CP464_RS12620	COG0395	ABC-type sugar transport system, permease component
CP464_RS12635	COG0531	amino acid
CP464_RS12640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP464_RS12645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP464_RS12650	COG1834	amidinotransferase
CP464_RS12655	COG1522	sequence-specific DNA binding
CP464_RS12685	COG2223	nitrite transmembrane transporter activity
CP464_RS12710	COG0477	Major facilitator Superfamily
CP464_RS12720	COG1045	serine acetyltransferase
CP464_RS12735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CP464_RS12915	COG0657	acetylesterase activity
CP464_RS12930	COG1420	regulation of RNA biosynthetic process
CP464_RS12960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS12975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP464_RS12975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS12980	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP464_RS13045	COG1297	OPT oligopeptide transporter protein
CP464_RS13070	COG4208	sulfate ABC transporter
CP464_RS13080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CP464_RS13095	COG3387	PFAM Glycoside hydrolase 15-related
CP464_RS13120	COG1234	tRNA 3'-trailer cleavage
CP464_RS13140	COG1305	Transglutaminase-like
CP464_RS13170	COG1555	photosystem II stabilization
CP464_RS13170	COG1596	polysaccharide export
CP464_RS13185	COG2755	lipolytic protein G-D-S-L family
CP464_RS13195	COG0799	negative regulation of ribosome biogenesis
CP464_RS13200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP464_RS13230	COG0542	response to heat
CP464_RS13260	COG5651	PPE family
CP464_RS13280	COG0668	transmembrane transport
CP464_RS13285	COG5002	protein histidine kinase activity
CP464_RS13295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP464_RS13315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP464_RS13340	COG1301	dicarboxylic acid transport
CP464_RS13345	COG1530	ribonuclease E activity
CP464_RS13360	COG0285	dihydrofolate synthase activity
CP464_RS13370	COG3268	Saccharopine dehydrogenase
CP464_RS13375	COG1388	LysM domain
CP464_RS13395	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP464_RS13400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP464_RS13400	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP464_RS13410	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP464_RS13415	COG2040	homocysteine
CP464_RS13435	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP464_RS13450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP464_RS13465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP464_RS13495	COG0366	Alpha amylase catalytic
CP464_RS13515	COG0824	Thioesterase
CP464_RS13520	COG2902	Dehydrogenase
CP464_RS13570	COG0657	acetylesterase activity
CP464_RS13585	COG0657	acetylesterase activity
CP464_RS13625	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CP464_RS13630	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP464_RS13650	COG2030	dehydratase
CP464_RS13655	COG1960	acyl-CoA dehydrogenase activity
CP464_RS13665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP464_RS13680	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS13700	COG0300	oxidoreductase activity
CP464_RS13705	COG0433	COG0433 Predicted ATPase
CP464_RS13725	COG3328	transposase activity
CP464_RS13775	COG1376	ErfK ybiS ycfS ynhG family protein
CP464_RS13820	COG3757	hydrolase, family 25
CP464_RS13840	COG1715	Restriction endonuclease
CP464_RS13870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP464_RS13940	COG1487	ribonuclease activity
CP464_RS13985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP464_RS13995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP464_RS14000	COG0432	Pfam Uncharacterised protein family UPF0047
CP464_RS14020	COG5473	translation initiation factor activity
CP464_RS14120	COG0596	Alpha beta hydrolase
CP464_RS14155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP464_RS14180	COG3320	Male sterility
CP464_RS14180	COG1022	Amp-dependent synthetase and ligase
CP464_RS14260	COG1946	Acyl-CoA thioesterase
CP464_RS14275	COG5651	PPE family
CP464_RS14315	COG3391	amine dehydrogenase activity
CP464_RS14320	COG4762	Protein conserved in bacteria
CP464_RS14435	COG1366	Belongs to the anti-sigma-factor antagonist family
CP464_RS14455	COG0640	Transcriptional regulator
CP464_RS14460	COG0798	PFAM Bile acid sodium symporter
CP464_RS14470	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS14500	COG4974	Belongs to the 'phage' integrase family
CP464_RS14650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP464_RS14725	COG1131	(ABC) transporter
CP464_RS14740	COG0531	amino acid
CP464_RS14745	COG0569	domain protein
CP464_RS14885	COG1388	LysM domain
CP464_RS14890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP464_RS14910	COG1960	acyl-CoA dehydrogenase activity
CP464_RS14915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP464_RS14945	COG1196	nuclear chromosome segregation
CP464_RS15000	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
CP464_RS15010	COG3391	amine dehydrogenase activity
CP464_RS15025	COG1842	Phage shock protein A
CP464_RS15040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP464_RS15085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CP464_RS15135	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS15175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP464_RS15205	COG1522	sequence-specific DNA binding
CP464_RS15210	COG0686	Belongs to the AlaDH PNT family
CP464_RS15255	COG1960	acyl-CoA dehydrogenase activity
CP464_RS15260	COG0183	Belongs to the thiolase family
CP464_RS15280	COG2977	Belongs to the P-Pant transferase superfamily
CP464_RS15285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP464_RS15315	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS15320	COG3609	addiction module antidote protein, CC2985 family
CP464_RS15425	COG1353	crispr-associated protein
CP464_RS15460	COG3744	PilT protein domain protein
CP464_RS15465	COG4118	positive regulation of growth
CP464_RS15475	COG3842	ATPase activity
CP464_RS15480	COG1653	transport
CP464_RS15485	COG0395	ABC-type sugar transport system, permease component
CP464_RS15500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CP464_RS15550	COG1648	precorrin-2 dehydrogenase activity
CP464_RS15550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP464_RS15595	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CP464_RS15615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP464_RS15650	COG2161	toxin-antitoxin pair type II binding
CP464_RS15655	COG2026	Addiction module toxin, RelE StbE family
CP464_RS15735	COG0233	cytoplasmic translational termination
CP464_RS15750	COG0745	RESPONSE REGULATOR receiver
CP464_RS15775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP464_RS15885	COG1686	Belongs to the peptidase S11 family
CP464_RS15920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP464_RS16010	COG3321	synthase
CP464_RS16010	COG0604	alcohol dehydrogenase
CP464_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS16080	COG0604	alcohol dehydrogenase
CP464_RS16080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS16080	COG4221	oxidoreductase activity
CP464_RS16080	COG3321	synthase
CP464_RS16085	COG3321	synthase
CP464_RS16100	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS16150	COG1819	glycosyl
CP464_RS16175	COG0701	Predicted permease
CP464_RS16200	COG0742	ribosomal rna small subunit methyltransferase
CP464_RS16205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CP464_RS16220	COG0657	acetylesterase activity
CP464_RS16225	COG0656	L-ascorbic acid biosynthetic process
CP464_RS16230	COG0656	L-ascorbic acid biosynthetic process
CP464_RS16245	COG1461	Dihydroxyacetone kinase
CP464_RS16285	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP464_RS16320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP464_RS16350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP464_RS16355	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP464_RS16365	COG0473	3-isopropylmalate dehydrogenase activity
CP464_RS16390	COG2972	Histidine kinase
CP464_RS16400	COG0390	transport system, permease component
CP464_RS16425	COG2259	Doxx family
CP464_RS16455	COG0154	amidase activity
CP464_RS16510	COG5651	PPE family
CP464_RS16520	COG3328	transposase activity
CP464_RS16585	COG0110	maltose O-acetyltransferase activity
CP464_RS16590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP464_RS16620	COG1119	ATPase activity
CP464_RS16625	COG3830	Belongs to the UPF0237 family
CP464_RS16625	COG0560	Phosphoserine phosphatase
CP464_RS16670	COG1309	transcriptional regulator
CP464_RS16730	COG2186	Transcriptional regulator
CP464_RS16735	COG1960	acyl-CoA dehydrogenase activity
CP464_RS16745	COG1966	Carbon starvation protein
CP464_RS16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS16905	COG2354	Protein conserved in bacteria
CP464_RS16930	COG0657	acetylesterase activity
CP464_RS16940	COG2337	Toxic component of a toxin-antitoxin (TA) module
CP464_RS16960	COG2177	Part of the ABC transporter FtsEX involved in
CP464_RS16965	COG2884	Cell division ATP-binding protein ftsE
CP464_RS16975	COG0668	transmembrane transport
CP464_RS16990	COG0277	FAD linked oxidase domain protein
CP464_RS17005	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP464_RS17015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CP464_RS17035	COG3328	transposase activity
CP464_RS17085	COG3629	intracellular signal transduction
CP464_RS17110	COG2801	Transposase and inactivated derivatives
CP464_RS17155	COG5651	PPE family
CP464_RS17170	COG0483	inositol monophosphate 1-phosphatase activity
CP464_RS17185	COG1960	acyl-CoA dehydrogenase activity
CP464_RS17190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS17190	COG0604	alcohol dehydrogenase
CP464_RS17190	COG4221	oxidoreductase activity
CP464_RS17190	COG3321	synthase
CP464_RS17240	COG1034	ATP synthesis coupled electron transport
CP464_RS17250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP464_RS17305	COG0714	Associated with various cellular activities
CP464_RS17350	COG1309	transcriptional regulator
CP464_RS17360	COG0154	amidase activity
CP464_RS17375	COG0748	coenzyme F420 binding
CP464_RS17405	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CP464_RS17410	COG1396	sequence-specific DNA binding
CP464_RS17450	COG2826	transposase and inactivated derivatives, IS30 family
CP464_RS17475	COG1615	UPF0182 protein
CP464_RS17500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP464_RS17520	COG2816	NAD+ diphosphatase activity
CP464_RS17530	COG0210	DNA helicase
CP464_RS17545	COG0596	Alpha beta hydrolase
CP464_RS17550	COG3695	enzyme binding
CP464_RS17590	COG0513	Belongs to the DEAD box helicase family
CP464_RS17605	COG0406	alpha-ribazole phosphatase activity
CP464_RS17625	COG1597	lipid kinase activity
CP464_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS17675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP464_RS17685	COG2135	peptidase activity
CP464_RS17690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP464_RS17695	COG1162	GTPase activity
CP464_RS17715	COG2326	polyphosphate kinase activity
CP464_RS17735	COG4651	solute:proton antiporter activity
CP464_RS17735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP464_RS17745	COG2020	methyltransferase activity
CP464_RS17760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP464_RS17780	COG5002	protein histidine kinase activity
CP464_RS17780	COG5000	phosphorelay sensor kinase activity
CP464_RS17815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP464_RS17820	COG0531	amino acid
CP464_RS17825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP464_RS17830	COG1482	cell wall glycoprotein biosynthetic process
CP464_RS17840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP464_RS17900	COG1316	TRANSCRIPTIONal
CP464_RS17925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP464_RS17930	COG0659	secondary active sulfate transmembrane transporter activity
CP464_RS17965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP464_RS17975	COG0424	maF-like protein
CP464_RS17990	COG4770	biotin carboxylase activity
CP464_RS18020	COG1522	sequence-specific DNA binding
CP464_RS18030	COG1012	belongs to the aldehyde dehydrogenase family
CP464_RS18040	COG1309	transcriptional regulator
CP464_RS18045	COG1201	RNA secondary structure unwinding
CP464_RS18060	COG3119	arylsulfatase activity
CP464_RS18060	COG3408	Glycogen debranching enzyme
CP464_RS18065	COG0564	pseudouridine synthase activity
CP464_RS18090	COG1473	amidohydrolase
CP464_RS18090	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP464_RS18105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP464_RS18115	COG3511	phospholipase C
CP464_RS18155	COG2009	succinate dehydrogenase
CP464_RS18165	COG1053	succinate dehydrogenase
CP464_RS18170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP464_RS18210	COG3547	Transposase (IS116 IS110 IS902 family)
CP464_RS18215	COG1595	DNA-templated transcription, initiation
CP464_RS18220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP464_RS18225	COG1686	Belongs to the peptidase S11 family
CP464_RS18230	COG2814	Major facilitator Superfamily
CP464_RS18235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP464_RS18250	COG0789	Transcriptional regulator
CP464_RS18255	COG1295	ribonuclease BN
CP464_RS18275	COG2873	o-acetylhomoserine
CP464_RS18290	COG5651	PPE family
CP464_RS18305	COG5651	PPE family
CP464_RS18305	COG5651	PPE family
CP464_RS18335	COG5651	PPE family
CP464_RS18335	COG5651	PPE family
CP464_RS18335	COG5651	PPE family
CP464_RS18345	COG0277	FAD linked oxidase domain protein
CP464_RS18370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP464_RS18390	COG1716	ATPase activity
CP464_RS18390	COG0842	Transport permease protein
CP464_RS18390	COG1131	(ABC) transporter
CP464_RS18395	COG1357	PFAM Pentapeptide repeats (8 copies)
CP464_RS18410	COG2018	Roadblock/LC7 domain
CP464_RS18420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CP464_RS18445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS18460	COG1024	Enoyl-CoA hydratase
CP464_RS18480	COG1657	PFAM Prenyltransferase squalene oxidase
CP464_RS18490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP464_RS18495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP464_RS18510	COG0142	geranyltranstransferase activity
CP464_RS18515	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CP464_RS18535	COG2030	dehydratase
CP464_RS18540	COG0406	alpha-ribazole phosphatase activity
CP464_RS18550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS18700	COG0456	acetyltransferase
CP464_RS18730	COG5651	PPE family
CP464_RS18735	COG5651	PPE family
CP464_RS18740	COG1484	DNA-dependent DNA replication
CP464_RS18745	COG4584	PFAM Integrase catalytic
CP464_RS18775	COG0076	glutamate decarboxylase activity
CP464_RS18835	COG4842	Belongs to the WXG100 family
CP464_RS18840	COG4842	Belongs to the WXG100 family
CP464_RS18850	COG1674	ftsk spoiiie
CP464_RS18860	COG1404	Belongs to the peptidase S8 family
CP464_RS18915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP464_RS18930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP464_RS18965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP464_RS18970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP464_RS18975	COG0028	Belongs to the TPP enzyme family
CP464_RS19000	COG0477	Major facilitator Superfamily
CP464_RS19015	COG1752	Esterase of the alpha-beta hydrolase superfamily
CP464_RS19020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS19040	COG1316	TRANSCRIPTIONal
CP464_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS19055	COG2259	Doxx family
CP464_RS19060	COG0657	acetylesterase activity
CP464_RS19065	COG1695	Transcriptional regulator
CP464_RS19075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CP464_RS19100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP464_RS19125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP464_RS19130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP464_RS19145	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19150	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19155	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS19160	COG0657	acetylesterase activity
CP464_RS19165	COG0657	acetylesterase activity
CP464_RS19170	COG0028	Belongs to the TPP enzyme family
CP464_RS19190	COG0657	acetylesterase activity
CP464_RS19205	COG1024	Enoyl-CoA hydratase
CP464_RS19215	COG2124	cytochrome p450
CP464_RS19225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP464_RS19235	COG0183	Belongs to the thiolase family
CP464_RS19240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP464_RS19255	COG4638	Rieske (2fe-2S)
CP464_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS19315	COG3971	2-oxopent-4-enoate hydratase activity
CP464_RS19320	COG1053	succinate dehydrogenase
CP464_RS19325	COG2030	dehydratase
CP464_RS19345	COG2030	dehydratase
CP464_RS19350	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19355	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19365	COG0183	Belongs to the thiolase family
CP464_RS19375	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS19390	COG1024	Enoyl-CoA hydratase
CP464_RS19410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP464_RS19420	COG0183	Belongs to the thiolase family
CP464_RS19440	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19445	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS19450	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19455	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19460	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19465	COG0436	Aminotransferase
CP464_RS19515	COG1960	acyl-CoA dehydrogenase activity
CP464_RS19520	COG1309	transcriptional regulator
CP464_RS19525	COG1609	Transcriptional regulator
CP464_RS19545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP464_RS19580	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP464_RS19600	COG0657	acetylesterase activity
CP464_RS19620	COG0739	heme binding
CP464_RS19695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP464_RS19740	COG2267	carboxylic ester hydrolase activity
CP464_RS19790	COG2027	D-alanyl-D-alanine carboxypeptidase
CP464_RS19805	COG2244	polysaccharide biosynthetic process
CP464_RS19850	COG3328	transposase activity
CP464_RS19855	COG2184	nucleotidyltransferase activity
CP464_RS19875	COG0470	DNA polymerase III
CP464_RS19900	COG1205	dead DEAH box helicase
CP464_RS19900	COG1111	helicase
CP464_RS19905	COG0657	acetylesterase activity
CP464_RS19925	COG0657	acetylesterase activity
CP464_RS19985	COG4172	Belongs to the ABC transporter superfamily
CP464_RS19990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP464_RS19995	COG0601	transmembrane transport
CP464_RS20035	COG0494	nUDIX hydrolase
CP464_RS20060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP464_RS20095	COG1408	metallophosphoesterase
CP464_RS20100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP464_RS20150	COG0714	Associated with various cellular activities
CP464_RS20175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP464_RS20200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP464_RS20210	COG0121	glutamine amidotransferase
CP464_RS20215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP464_RS20265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP464_RS20290	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP464_RS20305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP464_RS20315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP464_RS20345	COG1063	alcohol dehydrogenase
CP464_RS20350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP464_RS20350	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP464_RS20355	COG0477	Major facilitator Superfamily
CP464_RS20360	COG2226	methyltransferase
CP464_RS20370	COG1793	dna ligase
CP464_RS20420	COG2072	flavoprotein involved in K transport
CP464_RS20430	COG0640	Transcriptional regulator
CP464_RS20455	COG1569	PIN domain
CP464_RS20460	COG3311	Transcriptional regulator
CP464_RS20480	COG0590	tRNA wobble adenosine to inosine editing
CP464_RS20490	COG0287	Prephenate dehydrogenase
CP464_RS20510	COG0517	IMP dehydrogenase activity
CP464_RS20510	COG1125	glycine betaine transport
CP464_RS20520	COG5416	Lipopolysaccharide assembly protein A domain
CP464_RS20530	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CP464_RS20540	COG2205	protein histidine kinase activity
CP464_RS20545	COG0745	RESPONSE REGULATOR receiver
CP464_RS20550	COG0739	heme binding
CP464_RS20595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP464_RS20660	COG1088	dTDP-glucose 4,6-dehydratase activity
CP464_RS20705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP464_RS20720	COG1234	tRNA 3'-trailer cleavage
CP464_RS20725	COG1960	acyl-CoA dehydrogenase activity
CP464_RS20735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP464_RS20740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP464_RS20740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP464_RS20740	COG3321	synthase
CP464_RS20745	COG0318	PFAM AMP-dependent synthetase and ligase
CP464_RS20750	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CP464_RS20765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP464_RS20780	COG1216	Glycosyl transferase, family 2
CP464_RS20800	COG0657	acetylesterase activity
CP464_RS20815	COG0561	phosphatase activity
CP464_RS20850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP464_RS20860	COG5651	PPE family
CP464_RS20865	COG2409	Drug exporters of the RND superfamily
CP464_RS20865	COG1511	domain protein
CP464_RS20875	COG3321	synthase
CP464_RS20875	COG1028	Short-chain dehydrogenase reductase Sdr
CP464_RS20875	COG0604	alcohol dehydrogenase
CP464_RS20920	COG2207	Transcriptional regulator
CP464_RS20960	COG1316	TRANSCRIPTIONal
CP464_RS21025	COG2119	membrane
CP464_RS21065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP464_RS21065	COG1796	DNA polymerase
CP464_RS21080	COG0070	glutamate synthase
CP464_RS21080	COG0069	glutamate synthase activity
CP464_RS21080	COG0067	glutamate synthase
CP464_RS21190	COG4932	domain protein
CP464_RS21210	COG1404	Belongs to the peptidase S8 family
CP464_RS21215	COG0464	growth
CP464_RS21225	COG1404	Belongs to the peptidase S8 family
CP464_RS21255	COG5651	PPE family
CP464_RS21265	COG1674	ftsk spoiiie
CP464_RS21355	COG1595	DNA-templated transcription, initiation
CP464_RS21375	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP464_RS21375	COG3409	Peptidoglycan-binding domain 1 protein
CP464_RS21395	COG1192	Involved in chromosome partitioning
CP464_RS21415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP464_RS21425	COG0230	Belongs to the bacterial ribosomal protein bL34 family