CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 Gene3D G3DSA:3.40.50.1820 7 314 5.6E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 Pfam PF12697 Alpha/beta hydrolase family 45 306 1.1E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 PRINTS PR00412 Epoxide hydrolase signature 48 66 7.9E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 PRINTS PR00412 Epoxide hydrolase signature 68 83 7.9E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 PRINTS PR00412 Epoxide hydrolase signature 114 127 7.9E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 PRINTS PR00412 Epoxide hydrolase signature 289 311 7.9E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS06155 aae312e32872ec9b95bddb8bcd1b7d6e 316 SUPERFAMILY SSF53474 18 313 3.77E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 PRINTS PR00297 10kDa chaperonin signature 64 76 2.2E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 PRINTS PR00297 10kDa chaperonin signature 28 49 2.2E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 PRINTS PR00297 10kDa chaperonin signature 6 21 2.2E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 PRINTS PR00297 10kDa chaperonin signature 85 98 2.2E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 Hamap MF_00580 10 kDa chaperonin [groS]. 5 99 25.581 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 SMART SM00883 5 98 1.0E-55 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 Gene3D G3DSA:2.30.33.40 1 99 7.1E-40 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 Pfam PF00166 Chaperonin 10 Kd subunit 5 98 6.1E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CP478_RS18705 213a13f150f54909558fc71eb463d0db 100 SUPERFAMILY SSF50129 4 99 2.35E-35 T 28-03-2018 IPR011032 GroES-like CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 744 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 SUPERFAMILY SSF53659 5 743 0.0 T 28-03-2018 CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 PIRSF PIRSF009407 1 744 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 Gene3D G3DSA:3.40.718.10 426 715 5.0E-35 T 28-03-2018 CP478_RS00370 53bb04e930876bbd99c185cc7571144c 745 Gene3D G3DSA:3.40.718.10 79 367 4.4E-44 T 28-03-2018 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 Gene3D G3DSA:4.10.910.10 87 122 5.9E-25 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.833 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 Gene3D G3DSA:1.10.8.50 1 67 2.8E-23 T 28-03-2018 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 SUPERFAMILY SSF46946 2 121 7.07E-46 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.3E-51 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 PIRSF PIRSF002134 1 124 2.8E-44 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.4E-35 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18935 389c5d2acfaaf8ab7866d77f35b8bfef 124 Gene3D G3DSA:4.10.910.10 68 86 2.6E-16 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS00215 962723e0868ffb78f00eadc6a526b666 202 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 18 199 26.077 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CP478_RS00215 962723e0868ffb78f00eadc6a526b666 202 Gene3D G3DSA:3.40.1740.10 117 190 3.5E-10 T 28-03-2018 CP478_RS00215 962723e0868ffb78f00eadc6a526b666 202 Gene3D G3DSA:3.40.1740.10 6 101 8.0E-17 T 28-03-2018 CP478_RS00215 962723e0868ffb78f00eadc6a526b666 202 SUPERFAMILY SSF143456 16 196 4.19E-46 T 28-03-2018 CP478_RS00215 962723e0868ffb78f00eadc6a526b666 202 Pfam PF02622 Uncharacterized ACR, COG1678 31 185 3.6E-35 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 28 216 1.0E-22 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 SMART SM00342 259 341 2.2E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 325 341 3.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 325 3.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 Gene3D G3DSA:1.10.10.60 308 344 2.2E-11 T 28-03-2018 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 Gene3D G3DSA:1.10.10.10 235 307 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 SUPERFAMILY SSF46689 295 343 6.45E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS07645 32901b65154a5f3736da76f317d9d709 344 Pfam PF12833 Helix-turn-helix domain 266 343 8.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS14305 ad87babffddc6091b6cd0bb2d47032d9 316 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 12 302 1.6E-101 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CP478_RS04050 e4b6b96c3ddbcbec6e25bdccc79364a5 783 Pfam PF00934 PE family 1 93 4.1E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS04050 e4b6b96c3ddbcbec6e25bdccc79364a5 783 SUPERFAMILY SSF140459 8 84 3.14E-22 T 28-03-2018 CP478_RS20675 4ff4e36d1b8c60e821c47b784ee4d611 326 SUPERFAMILY SSF51735 1 314 1.05E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20675 4ff4e36d1b8c60e821c47b784ee4d611 326 Gene3D G3DSA:3.40.50.720 2 174 9.6E-42 T 28-03-2018 CP478_RS20675 4ff4e36d1b8c60e821c47b784ee4d611 326 Gene3D G3DSA:3.90.25.10 175 318 4.8E-37 T 28-03-2018 CP478_RS20675 4ff4e36d1b8c60e821c47b784ee4d611 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 7.6E-59 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 152 162 1.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 174 1.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 191 203 1.8E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 Gene3D G3DSA:2.10.109.10 121 236 1.4E-26 T 28-03-2018 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 SUPERFAMILY SSF46785 26 92 1.91E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 TIGRFAM TIGR00498 lexA: repressor LexA 25 236 7.9E-84 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 Pfam PF01726 LexA DNA binding domain 25 88 8.4E-30 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 SUPERFAMILY SSF51306 115 234 2.09E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 Gene3D G3DSA:1.10.10.10 25 91 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 Pfam PF00717 Peptidase S24-like 156 222 2.4E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CP478_RS14905 5f72dd87f134474995a39d528c783d39 236 Hamap MF_00015 LexA repressor [lexA]. 26 236 33.2 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 28 196 8.9E-35 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 Hamap MF_01389 Urease accessory protein UreG [ureG]. 24 222 43.323 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 SUPERFAMILY SSF52540 18 217 6.5E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 26 219 3.3E-82 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 PIRSF PIRSF005624 8 223 1.3E-42 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CP478_RS10070 4ba7d3c563dcbc890ab13432e3e100a7 224 Gene3D G3DSA:3.40.50.300 25 223 1.7E-17 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 SUPERFAMILY SSF81653 227 313 9.15E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Gene3D G3DSA:1.20.1110.10 128 431 1.2E-32 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 157 711 5.2E-168 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 228 689 3.1E-71 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Gene3D G3DSA:3.30.70.100 12 84 3.1E-5 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Gene3D G3DSA:3.40.50.1000 529 681 1.2E-38 T 28-03-2018 IPR023214 HAD-like domain CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 SUPERFAMILY SSF56784 464 708 1.92E-54 T 28-03-2018 IPR023214 HAD-like domain CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 SUPERFAMILY SSF56784 405 424 1.92E-54 T 28-03-2018 IPR023214 HAD-like domain CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Pfam PF00122 E1-E2 ATPase 227 386 5.9E-40 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 408 414 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Gene3D G3DSA:3.40.1110.10 432 528 1.9E-27 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 543 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 565 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 608 627 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 406 420 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 644 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 264 278 4.9E-26 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 Pfam PF00702 haloacid dehalogenase-like hydrolase 402 622 2.2E-45 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 138 711 8.9E-123 T 28-03-2018 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 SUPERFAMILY SSF81665 162 210 3.66E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS17930 0139be10806ad93d86190158130cdb5f 718 SUPERFAMILY SSF81665 315 424 3.66E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS20690 a14e65088b352efb6a9beeb46be5a472 308 Gene3D G3DSA:3.40.50.150 1 289 4.0E-56 T 28-03-2018 CP478_RS20690 a14e65088b352efb6a9beeb46be5a472 308 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 1.6E-65 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS20690 a14e65088b352efb6a9beeb46be5a472 308 SUPERFAMILY SSF53335 15 289 1.19E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20690 a14e65088b352efb6a9beeb46be5a472 308 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 284 1.6E-76 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 302 419 8.3E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 207 223 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 47 294 2.0E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Gene3D G3DSA:3.40.47.10 39 306 8.7E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 422 479 4.9E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 SMART SM00825 Beta-ketoacyl synthase 49 472 2.3E-215 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Pfam PF08990 Erythronolide synthase docking 18 40 9.9E-7 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 SUPERFAMILY SSF101173 14 47 6.15E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 Gene3D G3DSA:3.40.47.10 309 470 8.1E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16100 f409d7bb92f3b9a6e30693cb10ed752c 496 SUPERFAMILY SSF53901 41 415 3.49E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 Gene3D G3DSA:3.50.50.60 1 353 4.2E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 3.3E-13 T 28-03-2018 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.3E-13 T 28-03-2018 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.3E-13 T 28-03-2018 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 3.3E-13 T 28-03-2018 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 Pfam PF01494 FAD binding domain 1 332 7.1E-18 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 SUPERFAMILY SSF51905 2 167 1.86E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03080 06b8ab04f8693f2f64a5d36b0285f9ba 388 SUPERFAMILY SSF51905 262 369 1.86E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 Pfam PF13183 4Fe-4S dicluster domain 140 216 2.4E-15 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 SUPERFAMILY SSF54292 6 103 1.57E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 17 219 3.6E-43 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 SUPERFAMILY SSF46548 124 228 4.53E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 Gene3D G3DSA:1.10.1060.10 103 238 5.2E-12 T 28-03-2018 CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 Gene3D G3DSA:3.10.20.30 2 102 1.3E-27 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS01335 9fd5c44f12b80e2604f8ce2f9d853ffe 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 105 9.7E-27 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Gene3D G3DSA:2.40.50.140 1008 1100 1.7E-11 T 28-03-2018 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Gene3D G3DSA:1.10.150.280 814 920 1.0E-5 T 28-03-2018 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 SMART SM00481 11 78 1.2E-32 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 320 762 1.2E-160 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Pfam PF14579 Helix-hairpin-helix motif 835 922 2.9E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Pfam PF02811 PHP domain 12 198 3.6E-46 T 28-03-2018 IPR004013 PHP domain GO:0003824 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 Gene3D G3DSA:3.20.20.140 4 273 1.6E-46 T 28-03-2018 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 10 1061 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 SUPERFAMILY SSF89550 124 273 2.09E-27 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CP478_RS08475 568adbea791abb3430ef6a81594db5b3 1184 SUPERFAMILY SSF89550 10 96 2.09E-27 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 488 33.79 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 SMART SM00962 100 302 3.3E-109 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Pfam PF00448 SRP54-type protein, GTPase domain 100 302 1.4E-68 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 SMART SM00963 1 86 2.0E-33 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Pfam PF02978 Signal peptide binding domain 334 431 7.0E-30 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 5.8E-21 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 432 1.9E-180 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 275 288 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 SUPERFAMILY SSF52540 42 360 1.42E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Gene3D G3DSA:1.20.120.140 217 316 4.8E-31 T 28-03-2018 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 SUPERFAMILY SSF47446 334 434 1.36E-32 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Gene3D G3DSA:3.40.50.300 99 216 6.1E-17 T 28-03-2018 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Gene3D G3DSA:1.10.260.30 333 435 5.6E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 SMART SM00382 99 307 3.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS15925 ab6940120754884ad27a4f3456d94179 525 Gene3D G3DSA:1.20.120.140 1 91 5.7E-28 T 28-03-2018 CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 SUPERFAMILY SSF56281 280 619 1.82E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 Pfam PF00753 Metallo-beta-lactamase superfamily 353 554 3.8E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 SMART SM00849 355 554 2.9E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 Gene3D G3DSA:3.60.15.10 330 580 1.7E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 SUPERFAMILY SSF56529 72 300 3.01E-58 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 Gene3D G3DSA:3.90.850.10 35 299 1.4E-56 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS05120 64861e502b2590f183997515ea75ed5c 644 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 300 4.4E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.90.180.10 1602 1683 5.9E-4 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF00550 Phosphopantetheine attachment site 1984 2047 2.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF53901 32 406 1.29E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF13602 Zinc-binding dehydrogenase 1549 1679 3.6E-17 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2006 2021 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.366.10 561 697 4.6E-43 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF00698 Acyl transferase domain 564 884 1.6E-92 T 28-03-2018 IPR014043 Acyl transferase CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF47336 1972 2055 1.83E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF51735 1691 1944 1.89E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.90.180.10 1369 1496 4.6E-25 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.366.10 746 854 1.1E-23 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF51735 1214 1355 1.61E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00823 Phosphopantetheine attachment site 1979 2051 1.7E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00826 934 1096 2.1E-70 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.30.70.250 698 745 5.4E-17 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF50129 1381 1506 1.03E-22 T 28-03-2018 IPR011032 GroES-like CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF51735 1472 1608 9.87E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF14765 Polyketide synthase dehydratase 934 1204 1.5E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM01294 1980 2047 8.4E-5 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 408 2.8E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF52151 754 850 3.92E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF52151 561 690 3.92E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF08659 KR domain 1694 1872 2.7E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 528 6.1E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00829 1377 1679 2.2E-165 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1694 1874 6.0E-57 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.47.10 28 296 8.0E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1395 1449 1.3E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 284 6.7E-91 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:1.10.1200.10 1963 2060 5.7E-20 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.50.720 1497 1601 3.7E-20 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SUPERFAMILY SSF55048 689 753 1.44E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.50.720 1687 1934 4.3E-47 T 28-03-2018 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 Gene3D G3DSA:3.40.47.10 299 459 3.0E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00825 Beta-ketoacyl synthase 37 461 1.4E-212 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS09085 2b5bf9a6c705786c555cf99fde7f769f 2126 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 866 5.2E-119 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS07455 5115e89c5609c520d6325f0dc77ea7a8 250 Gene3D G3DSA:3.30.70.1230 32 198 5.9E-17 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07455 5115e89c5609c520d6325f0dc77ea7a8 250 SUPERFAMILY SSF55073 35 209 3.61E-23 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS14580 75ff2f9544578fde14d11010a640672d 375 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 77 128 1.7E-8 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CP478_RS14580 75ff2f9544578fde14d11010a640672d 375 Pfam PF00589 Phage integrase family 182 356 3.8E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS14580 75ff2f9544578fde14d11010a640672d 375 Gene3D G3DSA:1.10.443.10 179 358 4.2E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS14580 75ff2f9544578fde14d11010a640672d 375 SUPERFAMILY SSF56349 77 362 9.42E-54 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS14580 75ff2f9544578fde14d11010a640672d 375 Gene3D G3DSA:1.10.150.130 66 178 2.6E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CP478_RS05395 84abef588d6d336486a9ab18b18d4216 386 Gene3D G3DSA:2.40.370.10 251 386 5.5E-43 T 28-03-2018 IPR023374 AttH-like domain CP478_RS05395 84abef588d6d336486a9ab18b18d4216 386 Pfam PF07143 CrtC N-terminal lipocalin domain 71 246 1.4E-53 T 28-03-2018 IPR010791 AttH domain CP478_RS05395 84abef588d6d336486a9ab18b18d4216 386 Gene3D G3DSA:2.40.370.10 59 250 1.6E-56 T 28-03-2018 IPR023374 AttH-like domain CP478_RS05395 84abef588d6d336486a9ab18b18d4216 386 Pfam PF17186 Lipocalin-like domain 250 381 1.6E-40 T 28-03-2018 CP478_RS05395 84abef588d6d336486a9ab18b18d4216 386 SUPERFAMILY SSF159245 49 381 5.23E-96 T 28-03-2018 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 SMART SM00905 5 117 8.3E-50 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 Pfam PF02152 Dihydroneopterin aldolase 5 116 5.6E-35 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 TIGRFAM TIGR00526 folB_dom: FolB domain 2 120 5.0E-41 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 Gene3D G3DSA:3.30.1130.10 1 119 1.9E-37 T 28-03-2018 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 2.3E-44 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CP478_RS19695 f086ef7963f2fbdf41bb6257803e89bc 133 SUPERFAMILY SSF55620 3 119 4.67E-38 T 28-03-2018 CP478_RS13955 2bbda4041137995a135b6fa0526da878 137 Pfam PF01850 PIN domain 4 122 1.2E-14 T 28-03-2018 IPR002716 PIN domain CP478_RS13955 2bbda4041137995a135b6fa0526da878 137 SUPERFAMILY SSF88723 1 120 7.29E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13955 2bbda4041137995a135b6fa0526da878 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 127 15.002 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS13955 2bbda4041137995a135b6fa0526da878 137 Gene3D G3DSA:3.40.50.1010 2 136 4.9E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 7.8E-44 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 7.8E-44 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 7.8E-44 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 7.8E-44 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 7.8E-44 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 SUPERFAMILY SSF54919 2 135 6.55E-54 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 33.848 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 Gene3D G3DSA:3.30.70.141 1 54 1.1E-17 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 Gene3D G3DSA:3.30.70.141 55 136 2.7E-32 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 8.9E-54 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS13365 572fe9e7b8cfb0a215e5a59ba2a0fa1c 136 SMART SM00562 2 136 2.0E-77 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 SUPERFAMILY SSF51735 143 318 8.25E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 SMART SM01002 151 313 7.9E-77 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 SUPERFAMILY SSF52283 10 173 1.62E-45 T 28-03-2018 CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 Gene3D G3DSA:3.40.50.720 8 208 3.5E-40 T 28-03-2018 CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 SMART SM01003 12 142 5.8E-55 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 Gene3D G3DSA:3.40.50.720 209 365 7.2E-38 T 28-03-2018 CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 146 362 6.1E-66 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CP478_RS00850 2c49da1800c2147d39d64f1817bbb57a 366 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 12 141 2.1E-38 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1745 1924 2.5E-48 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00829 1409 1721 1.3E-152 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF14765 Polyketide synthase dehydratase 898 1175 9.3E-50 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 377 8.7E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF55048 660 726 4.58E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.50.720 1735 2008 2.5E-42 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.47.10 1 268 4.2E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.90.180.10 1630 1724 0.22 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.50.720 1552 1629 4.2E-15 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF51735 1741 1987 1.65E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.366.10 528 713 1.6E-44 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.90.180.10 1396 1551 4.9E-41 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF52151 538 662 3.14E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF52151 727 823 3.14E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF47336 2003 2083 3.53E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF51735 1516 1676 4.45E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF50129 1404 1537 9.43E-34 T 28-03-2018 IPR011032 GroES-like CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF00107 Zinc-binding dehydrogenase 1550 1640 3.3E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF08659 KR domain 1745 1923 1.1E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.47.10 271 429 1.4E-51 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:1.10.1200.10 2009 2083 7.0E-13 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00825 Beta-ketoacyl synthase 9 431 2.5E-185 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF00550 Phosphopantetheine attachment site 2010 2073 3.9E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 256 1.8E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF00698 Acyl transferase domain 538 853 3.3E-93 T 28-03-2018 IPR014043 Acyl transferase CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF53901 6 376 2.08E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00826 898 1059 6.3E-35 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.10.129.10 904 1019 3.4E-8 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Gene3D G3DSA:3.40.366.10 714 833 4.3E-22 T 28-03-2018 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SUPERFAMILY SSF51735 1186 1383 1.27E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 540 835 6.2E-89 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1426 1494 7.6E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 475 1.4E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS06475 7d3756d4d0babb609065e33f1f4a626c 2085 SMART SM00823 Phosphopantetheine attachment site 2012 2077 3.2E-13 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 SUPERFAMILY SSF50129 1 146 1.67E-36 T 28-03-2018 IPR011032 GroES-like CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 Pfam PF00107 Zinc-binding dehydrogenase 153 257 3.2E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 SUPERFAMILY SSF51735 114 274 2.46E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 SMART SM00829 10 326 4.4E-16 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 104 4.9E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 Gene3D G3DSA:3.40.50.720 138 296 6.1E-29 T 28-03-2018 CP478_RS07975 be53f69a62ba45e2010f7e483ec64c5c 328 Gene3D G3DSA:3.90.180.10 1 137 1.3E-38 T 28-03-2018 CP478_RS12655 f2b805d2f952f2414a613fee2db8e094 183 SUPERFAMILY SSF53383 1 178 9.31E-41 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS12655 f2b805d2f952f2414a613fee2db8e094 183 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 3 40 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS12655 f2b805d2f952f2414a613fee2db8e094 183 Pfam PF00202 Aminotransferase class-III 1 178 2.2E-40 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS12655 f2b805d2f952f2414a613fee2db8e094 183 Gene3D G3DSA:3.40.640.10 1 70 1.9E-21 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS12655 f2b805d2f952f2414a613fee2db8e094 183 Gene3D G3DSA:3.90.1150.10 71 182 6.2E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS13885 ecf69b968cc90884cd70ecc4d603c3fc 156 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 8 143 21.801 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CP478_RS13885 ecf69b968cc90884cd70ecc4d603c3fc 156 SUPERFAMILY SSF48013 10 138 1.24E-38 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS13885 ecf69b968cc90884cd70ecc4d603c3fc 156 Gene3D G3DSA:1.10.940.10 5 141 3.0E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS13885 ecf69b968cc90884cd70ecc4d603c3fc 156 Pfam PF01029 NusB family 11 138 1.6E-33 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS13885 ecf69b968cc90884cd70ecc4d603c3fc 156 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 10 139 3.7E-38 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 SUPERFAMILY SSF69593 304 482 5.49E-34 T 28-03-2018 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 40 226 1.1E-20 T 28-03-2018 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 Gene3D G3DSA:3.40.1130.10 301 547 7.9E-38 T 28-03-2018 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 Pfam PF01553 Acyltransferase 312 438 6.4E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 SUPERFAMILY SSF56784 36 227 3.36E-25 T 28-03-2018 IPR023214 HAD-like domain CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 40 238 6.7E-66 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 Gene3D G3DSA:3.40.50.1000 39 300 1.6E-12 T 28-03-2018 IPR023214 HAD-like domain CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 Pfam PF12710 haloacid dehalogenase-like hydrolase 40 223 2.5E-29 T 28-03-2018 CP478_RS13575 91af5b1e914e0f91ab5ad1a5e1c48408 580 SMART SM00563 327 441 1.8E-34 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS21265 dd4086bdb7d62ff704d7531a0b1df194 107 SUPERFAMILY SSF140453 4 99 2.22E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21265 dd4086bdb7d62ff704d7531a0b1df194 107 Gene3D G3DSA:1.10.287.1060 1 100 6.8E-6 T 28-03-2018 CP478_RS21265 dd4086bdb7d62ff704d7531a0b1df194 107 Pfam PF06013 Proteins of 100 residues with WXG 5 90 1.4E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19865 9216149d5e3c69beaa4dcc2471cf8fd7 409 Pfam PF00872 Transposase, Mutator family 6 379 1.1E-159 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 17 555 6.8E-130 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 Hamap MF_01491 Ribonuclease J [rnj]. 11 558 39.841 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 368 411 1.4E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 Gene3D G3DSA:3.60.15.10 9 455 6.0E-60 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 Pfam PF12706 Beta-lactamase superfamily domain 57 173 1.3E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 PIRSF PIRSF004803 11 558 1.7E-180 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 SMART SM00849 28 222 1.5E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS15080 306ecc779c4947bb6e5eb7cd5cee0c3e 558 SUPERFAMILY SSF56281 16 431 4.85E-89 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS14535 c2506d29c08b69f4180cd5ff9029352a 479 Pfam PF05065 Phage capsid family 196 475 5.1E-50 T 28-03-2018 IPR024455 Phage capsid CP478_RS14535 c2506d29c08b69f4180cd5ff9029352a 479 Gene3D G3DSA:3.30.2400.10 218 360 1.5E-15 T 28-03-2018 CP478_RS14535 c2506d29c08b69f4180cd5ff9029352a 479 SUPERFAMILY SSF56563 192 475 3.92E-32 T 28-03-2018 CP478_RS14535 c2506d29c08b69f4180cd5ff9029352a 479 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 177 475 2.7E-44 T 28-03-2018 IPR024455 Phage capsid CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 Gene3D G3DSA:1.10.12.10 240 288 7.5E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 294 1.3E-48 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 11 299 51.927 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 SUPERFAMILY SSF52096 20 296 3.03E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 Gene3D G3DSA:3.90.226.10 3 239 4.7E-68 T 28-03-2018 CP478_RS02935 177f51e27c0344824163ec668008a6c4 300 TIGRFAM TIGR01929 menB: naphthoate synthase 20 296 4.1E-134 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CP478_RS05315 0c7b954c33b01c15290f608ba9cfde90 529 Gene3D G3DSA:3.90.226.10 270 523 1.9E-57 T 28-03-2018 CP478_RS05315 0c7b954c33b01c15290f608ba9cfde90 529 Pfam PF01039 Carboxyl transferase domain 46 518 5.5E-144 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS05315 0c7b954c33b01c15290f608ba9cfde90 529 Gene3D G3DSA:3.90.226.10 8 269 3.8E-60 T 28-03-2018 CP478_RS05315 0c7b954c33b01c15290f608ba9cfde90 529 SUPERFAMILY SSF52096 22 260 3.95E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS05315 0c7b954c33b01c15290f608ba9cfde90 529 SUPERFAMILY SSF52096 230 510 5.65E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS08020 3c8f84f9461a147c37038eb006d7948c 266 Gene3D G3DSA:3.40.50.300 1 251 2.1E-38 T 28-03-2018 CP478_RS08020 3c8f84f9461a147c37038eb006d7948c 266 Pfam PF00005 ABC transporter 26 177 8.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08020 3c8f84f9461a147c37038eb006d7948c 266 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 249 8.6E-105 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CP478_RS08020 3c8f84f9461a147c37038eb006d7948c 266 SUPERFAMILY SSF52540 3 236 4.75E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08020 3c8f84f9461a147c37038eb006d7948c 266 SMART SM00382 35 229 0.0015 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 130 4.8E-50 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 SUPERFAMILY SSF48300 5 65 1.23E-14 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 130 7.4E-28 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 SUPERFAMILY SSF54736 58 130 1.36E-21 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 2.1E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 Gene3D G3DSA:3.30.1390.10 59 130 1.3E-28 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 130 24.177 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 103 8.0E-15 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03520 6062c70ec42b06dda547f366a5c87554 130 Gene3D G3DSA:1.20.5.710 4 58 6.8E-16 T 28-03-2018 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 45 56 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 SUPERFAMILY SSF102114 29 308 8.37E-66 T 28-03-2018 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 Gene3D G3DSA:3.20.20.70 26 360 1.6E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 30 360 3.9E-111 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 Pfam PF13353 4Fe-4S single cluster domain 46 122 6.3E-5 T 28-03-2018 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 30 360 39.565 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 SMART SM00729 39 244 3.3E-9 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 Pfam PF04055 Radical SAM superfamily 44 205 6.4E-26 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS04740 98a62b3e5240e38898ede779dd2dcc56 360 Pfam PF06463 Molybdenum Cofactor Synthesis C 211 342 3.6E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 759 34.321 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 12 315 1.0E-109 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 Gene3D G3DSA:3.20.20.210 392 759 9.0E-124 T 28-03-2018 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 Gene3D G3DSA:3.20.20.210 10 391 6.4E-135 T 28-03-2018 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 SUPERFAMILY SSF51726 12 396 8.24E-96 T 28-03-2018 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 SUPERFAMILY SSF51726 415 757 1.01E-113 T 28-03-2018 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 758 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 432 754 2.6E-154 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS06200 920f0e931d47e8bb42aa99a4a104f275 759 PIRSF PIRSF000382 9 759 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SMART SM01294 1427 1494 1.3E-5 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.40.47.10 27 295 2.1E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF55048 683 746 6.41E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF53901 433 454 8.49E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF53901 33 401 8.49E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.40.366.10 559 683 1.8E-33 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF51735 939 1142 2.04E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SMART SM00825 Beta-ketoacyl synthase 36 458 1.7E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 513 7.2E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.40.366.10 741 861 5.5E-18 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.40.50.720 1146 1398 5.4E-40 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF08659 KR domain 1153 1327 6.7E-46 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF00550 Phosphopantetheine attachment site 1431 1494 3.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.40.47.10 298 456 7.9E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 1.9E-97 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:1.10.1200.10 1418 1532 1.2E-15 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 865 8.8E-85 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1152 1329 1.0E-18 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Gene3D G3DSA:3.30.70.250 684 740 7.4E-17 T 28-03-2018 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 405 3.1E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF51735 1153 1379 2.23E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SMART SM00823 Phosphopantetheine attachment site 1426 1498 9.2E-20 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 Pfam PF00698 Acyl transferase domain 561 882 4.5E-109 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF47336 1421 1501 1.57E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF52151 560 685 9.42E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16020 a3eda989a5b42530a9f2d1ab622595da 1538 SUPERFAMILY SSF52151 748 847 9.42E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Gene3D G3DSA:2.40.30.10 207 303 5.0E-31 T 28-03-2018 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Gene3D G3DSA:3.40.50.300 77 204 5.6E-32 T 28-03-2018 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 PRINTS PR00315 GTP-binding elongation factor signature 96 107 3.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 PRINTS PR00315 GTP-binding elongation factor signature 80 90 3.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 PRINTS PR00315 GTP-binding elongation factor signature 133 142 3.9E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 SUPERFAMILY SSF52540 4 215 1.32E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 2.2E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 156 5.8E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Gene3D G3DSA:2.40.30.10 304 395 1.6E-32 T 28-03-2018 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Gene3D G3DSA:3.40.50.300 2 76 2.3E-11 T 28-03-2018 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Pfam PF03143 Elongation factor Tu C-terminal domain 301 394 2.1E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.171 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 3.0E-216 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 SUPERFAMILY SSF50465 304 396 8.35E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 SUPERFAMILY SSF50447 206 303 8.73E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 Pfam PF03144 Elongation factor Tu domain 2 226 296 1.2E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CP478_RS03700 b84c6639dcb8d43935952cd6dfae0e7e 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CP478_RS06880 74797396377eede710314807a3a7b83d 455 Gene3D G3DSA:3.30.465.10 94 238 3.3E-41 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS06880 74797396377eede710314807a3a7b83d 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 452 4.6E-65 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CP478_RS06880 74797396377eede710314807a3a7b83d 455 Gene3D G3DSA:3.30.43.10 1 93 6.3E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS06880 74797396377eede710314807a3a7b83d 455 SUPERFAMILY SSF56176 4 214 2.06E-69 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS06880 74797396377eede710314807a3a7b83d 455 Gene3D G3DSA:1.10.45.10 415 453 3.3E-15 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS06880 74797396377eede710314807a3a7b83d 455 SUPERFAMILY SSF55103 191 453 7.36E-56 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS06880 74797396377eede710314807a3a7b83d 455 Pfam PF01565 FAD binding domain 41 179 5.8E-42 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 SUPERFAMILY SSF54211 11 95 4.17E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 172 184 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 Gene3D G3DSA:3.30.230.40 99 210 1.5E-33 T 28-03-2018 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 Gene3D G3DSA:3.30.230.40 8 97 1.6E-31 T 28-03-2018 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 40 190 1.3E-57 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 11 210 41.288 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 SUPERFAMILY SSF54211 96 195 4.25E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS08760 e614cf35c54dc21ed38a44cd7a887e6e 210 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 70 83 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 Gene3D G3DSA:1.10.230.10 228 313 1.3E-21 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 Gene3D G3DSA:1.10.580.10 2 76 1.1E-11 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 Gene3D G3DSA:1.10.580.10 96 227 2.2E-34 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 Pfam PF00285 Citrate synthase, C-terminal domain 11 348 3.1E-82 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 ProSitePatterns PS00480 Citrate synthase signature. 247 259 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 PRINTS PR00143 Citrate synthase signature 165 180 1.5E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 PRINTS PR00143 Citrate synthase signature 299 315 1.5E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 PRINTS PR00143 Citrate synthase signature 319 333 1.5E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 PRINTS PR00143 Citrate synthase signature 240 260 1.5E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 PRINTS PR00143 Citrate synthase signature 187 215 1.5E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04850 8f1c1c8add2383dd3d7abfa911f4bdf4 373 SUPERFAMILY SSF48256 6 359 5.89E-94 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 366 4.2E-138 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 Hamap MF_00456 Glutamate 5-kinase [proB]. 13 265 34.024 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PIRSF PIRSF000729 8 369 1.1E-116 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 Pfam PF01472 PUA domain 281 351 7.3E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 SUPERFAMILY SSF53633 15 259 2.88E-57 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS13330 821ca460eb1b668882ec169b06388603 376 SMART SM00359 281 360 1.0E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 Gene3D G3DSA:2.30.130.10 279 367 2.2E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 Gene3D G3DSA:3.40.1160.10 2 269 2.9E-53 T 28-03-2018 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 SUPERFAMILY SSF88697 281 366 5.08E-15 T 28-03-2018 IPR015947 PUA-like domain CP478_RS13330 821ca460eb1b668882ec169b06388603 376 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 Pfam PF00696 Amino acid kinase family 15 239 1.1E-36 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PRINTS PR00474 Glutamate 5-kinase family signature 124 145 4.9E-52 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PRINTS PR00474 Glutamate 5-kinase family signature 84 112 4.9E-52 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 4.9E-52 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PRINTS PR00474 Glutamate 5-kinase family signature 50 64 4.9E-52 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS13330 821ca460eb1b668882ec169b06388603 376 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 4.9E-52 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 PIRSF PIRSF002162 1 178 2.6E-49 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 2.2E-73 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 Gene3D G3DSA:3.90.930.12 2 83 3.0E-27 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.0E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 Pfam PF00347 Ribosomal protein L6 91 165 7.4E-22 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 Pfam PF00347 Ribosomal protein L6 11 83 2.3E-16 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 Gene3D G3DSA:3.90.930.12 84 179 1.3E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.591 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 SUPERFAMILY SSF56053 84 178 4.97E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 SUPERFAMILY SSF56053 1 83 1.31E-24 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03895 0de1128a0a67f1fc52f88e60b125d44c 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS20795 689757eb6e67f32d43275d914efadade 637 Pfam PF13641 Glycosyltransferase like family 2 162 420 6.6E-50 T 28-03-2018 CP478_RS20795 689757eb6e67f32d43275d914efadade 637 Gene3D G3DSA:3.90.550.10 151 458 2.2E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20795 689757eb6e67f32d43275d914efadade 637 SUPERFAMILY SSF53448 335 440 1.59E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20795 689757eb6e67f32d43275d914efadade 637 SUPERFAMILY SSF53448 160 305 1.59E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS11655 8691cc02e1ba0ade5271d92183580ca5 105 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 92 2.1E-10 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CP478_RS13965 afec071c1deb2d551823af13c8ba2942 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 123 13.393 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS13965 afec071c1deb2d551823af13c8ba2942 125 Pfam PF01850 PIN domain 3 111 1.9E-11 T 28-03-2018 IPR002716 PIN domain CP478_RS13965 afec071c1deb2d551823af13c8ba2942 125 SUPERFAMILY SSF88723 3 122 1.85E-23 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13965 afec071c1deb2d551823af13c8ba2942 125 Gene3D G3DSA:3.40.50.1010 2 124 1.5E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 Gene3D G3DSA:1.20.1050.60 366 454 9.3E-23 T 28-03-2018 CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 39 755 1.6E-142 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 SUPERFAMILY SSF48208 289 689 9.3E-17 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 Gene3D G3DSA:3.30.2080.10 598 764 6.7E-51 T 28-03-2018 CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 Gene3D G3DSA:2.70.98.10 40 341 8.1E-84 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CP478_RS03130 95a81a66cb4e72a2335f380ac72ecf8a 877 Pfam PF07971 Glycosyl hydrolase family 92 266 749 2.0E-143 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CP478_RS04140 f0c1e9b8a3685e51399d2d182b48bf86 139 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 12 135 2.7E-17 T 28-03-2018 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 CP478_RS04140 f0c1e9b8a3685e51399d2d182b48bf86 139 Gene3D G3DSA:3.10.450.50 1 139 1.9E-18 T 28-03-2018 CP478_RS04140 f0c1e9b8a3685e51399d2d182b48bf86 139 SUPERFAMILY SSF54427 15 134 8.57E-22 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF53901 32 401 1.23E-99 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SMART SM00829 1356 1594 1.3E-108 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SMART SM00826 921 1081 3.9E-73 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SMART SM00825 Beta-ketoacyl synthase 36 457 1.0E-204 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF00698 Acyl transferase domain 561 872 1.3E-59 T 28-03-2018 IPR014043 Acyl transferase CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.40.50.720 1477 1590 1.4E-23 T 28-03-2018 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 854 5.5E-104 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.40.366.10 737 857 3.4E-29 T 28-03-2018 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1480 1501 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 2.3E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF52151 740 851 5.23E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF52151 560 681 5.23E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.40.366.10 559 696 2.5E-45 T 28-03-2018 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 526 3.9E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF08990 Erythronolide synthase docking 7 27 1.0E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF51735 1135 1334 3.9E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1373 1428 4.0E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF00107 Zinc-binding dehydrogenase 1491 1586 6.8E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.40.47.10 296 455 2.2E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF51735 1452 1585 4.26E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF14765 Polyketide synthase dehydratase 921 1188 7.1E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.30.70.250 697 736 7.6E-15 T 28-03-2018 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF50129 1355 1485 8.98E-29 T 28-03-2018 IPR011032 GroES-like CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 SUPERFAMILY SSF55048 686 747 4.05E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.90.180.10 1330 1476 4.6E-32 T 28-03-2018 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Gene3D G3DSA:3.40.47.10 26 293 1.2E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09090 7d2f8c76d53a6d9f2e0fc8728469c728 1602 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 281 7.9E-91 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS04490 d2ca7738ffa74dbbaee64ddba99ad966 140 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 20 57 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CP478_RS04490 d2ca7738ffa74dbbaee64ddba99ad966 140 Gene3D G3DSA:3.40.140.10 5 128 1.5E-14 T 28-03-2018 CP478_RS04490 d2ca7738ffa74dbbaee64ddba99ad966 140 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 68 1.2E-10 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CP478_RS04490 d2ca7738ffa74dbbaee64ddba99ad966 140 SUPERFAMILY SSF53927 7 86 2.84E-19 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS07550 b86fae1ca6130c06823f8f9b88724bcc 212 Pfam PF13649 Methyltransferase domain 49 142 1.2E-21 T 28-03-2018 CP478_RS07550 b86fae1ca6130c06823f8f9b88724bcc 212 Gene3D G3DSA:3.40.50.150 23 211 4.3E-32 T 28-03-2018 CP478_RS07550 b86fae1ca6130c06823f8f9b88724bcc 212 SUPERFAMILY SSF53335 34 191 2.28E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 Pfam PF01782 RimM N-terminal domain 4 92 1.5E-20 T 28-03-2018 IPR002676 RimM protein GO:0006364 CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 Pfam PF05239 PRC-barrel domain 101 172 6.3E-11 T 28-03-2018 IPR027275 PRC-barrel domain CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 Gene3D G3DSA:2.30.30.240 99 167 2.1E-19 T 28-03-2018 CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 SUPERFAMILY SSF50346 103 172 3.73E-16 T 28-03-2018 IPR011033 PRC-barrel-like CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 172 9.8E-41 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 Gene3D G3DSA:2.40.30.60 1 97 6.8E-26 T 28-03-2018 IPR002676 RimM protein GO:0006364 CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 172 22.114 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CP478_RS15880 844699867f610fe0beba7d4de7cf6ef2 176 SUPERFAMILY SSF50447 3 96 4.77E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 SMART SM00448 9 120 2.1E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 Gene3D G3DSA:1.10.10.10 132 234 7.3E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 Pfam PF00072 Response regulator receiver domain 11 120 4.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 SMART SM00862 156 230 2.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 SUPERFAMILY SSF52172 7 187 1.57E-41 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 4.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS20560 4deb1eb254a568f5e82ecd16744d702f 234 Gene3D G3DSA:3.40.50.2300 1 131 4.6E-38 T 28-03-2018 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Gene3D G3DSA:3.20.110.10 18 261 2.7E-39 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 20 258 9.7E-55 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 SUPERFAMILY SSF74650 350 586 4.55E-33 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 SUPERFAMILY SSF88713 23 256 1.05E-45 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 SUPERFAMILY SSF88688 256 355 4.9E-20 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 SUPERFAMILY SSF74650 799 985 3.14E-8 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1056 1130 5.2E-17 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 SMART SM00872 263 334 6.6E-18 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Gene3D G3DSA:2.60.40.10 1045 1152 0.003 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 799 994 2.3E-5 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 362 573 3.8E-10 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Gene3D G3DSA:1.20.1270.50 262 354 1.8E-19 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Pfam PF09261 Alpha mannosidase middle domain 264 332 7.0E-12 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CP478_RS03500 2c8c9c88923de5db674feb88190e7d80 1263 Gene3D G3DSA:2.60.40.1180 355 458 3.1E-15 T 28-03-2018 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 Gene3D G3DSA:3.40.190.10 131 221 1.8E-20 T 28-03-2018 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 46 255 6.1E-35 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 Gene3D G3DSA:3.40.190.10 2 130 2.4E-27 T 28-03-2018 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 Pfam PF13531 Bacterial extracellular solute-binding protein 41 258 2.2E-43 T 28-03-2018 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 SUPERFAMILY SSF53850 40 260 2.27E-53 T 28-03-2018 CP478_RS10095 3da3c5192dcea0adecadf95e7dc67c7e 261 PIRSF PIRSF004846 4 261 1.7E-60 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 Gene3D G3DSA:1.10.10.10 1 55 1.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 Pfam PF01037 Lrp/AsnC ligand binding domain 79 140 3.5E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 Gene3D G3DSA:3.30.70.920 57 138 2.1E-16 T 28-03-2018 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.2E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.2E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.2E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 SMART SM00344 4 111 5.0E-43 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 SUPERFAMILY SSF46785 3 64 1.94E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 9.4E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS12670 6e123d807341f95b6bd5228e75bc1ddb 148 SUPERFAMILY SSF54909 64 146 1.47E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS16450 63abf119f80c2c0909b8545809f6a349 204 SUPERFAMILY SSF50475 18 164 1.96E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS16450 63abf119f80c2c0909b8545809f6a349 204 Gene3D G3DSA:2.30.110.10 1 179 1.8E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS16450 63abf119f80c2c0909b8545809f6a349 204 Pfam PF01613 Flavin reductase like domain 22 162 4.4E-24 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS16450 63abf119f80c2c0909b8545809f6a349 204 SMART SM00903 22 168 8.3E-29 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS06305 219ff461c28cde314a9eb03b347a14e7 482 Pfam PF02720 Domain of unknown function (DUF222) 65 389 3.3E-98 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS06305 219ff461c28cde314a9eb03b347a14e7 482 Gene3D G3DSA:3.40.1800.10 371 448 0.001 T 28-03-2018 CP478_RS06305 219ff461c28cde314a9eb03b347a14e7 482 Gene3D G3DSA:1.10.10.10 86 175 3.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06305 219ff461c28cde314a9eb03b347a14e7 482 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 29 125 8.0E-48 T 28-03-2018 CP478_RS06305 219ff461c28cde314a9eb03b347a14e7 482 SMART SM00507 380 432 3.1E-7 T 28-03-2018 IPR003615 HNH nuclease CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 Gene3D G3DSA:3.20.20.80 37 500 1.6E-120 T 28-03-2018 CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 SUPERFAMILY SSF51445 54 501 2.63E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 Pfam PF16657 Maltogenic Amylase, C-terminal domain 501 581 2.7E-22 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 43 584 9.4E-283 T 28-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 Gene3D G3DSA:2.60.40.1180 502 589 1.5E-22 T 28-03-2018 CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 SMART SM00642 51 453 2.6E-115 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 SUPERFAMILY SSF51011 506 584 6.56E-17 T 28-03-2018 CP478_RS00690 6d3cf45d886779bd9daff0224c436128 601 Pfam PF00128 Alpha amylase, catalytic domain 66 422 5.1E-76 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 376 385 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 Gene3D G3DSA:1.10.630.10 2 440 1.1E-93 T 28-03-2018 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 251 268 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 341 365 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 373 383 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 36 55 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 301 319 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00463 E-class P450 group I signature 383 406 9.8E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00385 P450 superfamily signature 262 279 3.1E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00385 P450 superfamily signature 383 394 3.1E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00385 P450 superfamily signature 302 313 3.1E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 PRINTS PR00385 P450 superfamily signature 374 383 3.1E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 SUPERFAMILY SSF48264 8 436 8.12E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS01750 d04a1eddf8cfd19771fa65a4c7f4faec 449 Pfam PF00067 Cytochrome P450 10 420 1.4E-63 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 6.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 6.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 82 192 1.4E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 SUPERFAMILY SSF46689 21 78 1.7E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 Gene3D G3DSA:1.10.260.40 47 73 1.4E-12 T 28-03-2018 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 Gene3D G3DSA:1.10.357.10 74 201 4.8E-21 T 28-03-2018 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 9.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 Gene3D G3DSA:1.10.10.60 9 46 2.5E-10 T 28-03-2018 CP478_RS08525 482aa796ba8758ea93f9530547962c4a 202 SUPERFAMILY SSF48498 86 195 4.45E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 Pfam PF00122 E1-E2 ATPase 262 439 1.3E-40 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF81653 264 361 1.96E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 462 468 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF56784 547 749 2.99E-49 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF56784 459 478 2.99E-49 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 Gene3D G3DSA:3.40.1110.10 476 576 3.5E-25 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 728 1.9E-76 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 474 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 597 607 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 685 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 668 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 586 9.6E-28 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 211 752 2.1E-157 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 Gene3D G3DSA:3.40.50.1000 577 716 1.7E-37 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 Pfam PF00702 haloacid dehalogenase-like hydrolase 456 663 4.2E-40 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF81665 362 454 7.59E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF81665 699 726 7.59E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 SUPERFAMILY SSF81665 214 265 7.59E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 Gene3D G3DSA:1.20.1110.10 211 475 6.1E-26 T 28-03-2018 CP478_RS10865 bbc453d63aa185f5b27fa6a3685e7b75 771 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 212 751 4.1E-175 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS16475 4dc4bf3705b1eda391b26d718973e153 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 3.8E-31 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CP478_RS16475 4dc4bf3705b1eda391b26d718973e153 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.7E-16 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CP478_RS16475 4dc4bf3705b1eda391b26d718973e153 99 SUPERFAMILY SSF141000 3 94 3.27E-26 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CP478_RS16475 4dc4bf3705b1eda391b26d718973e153 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.898 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF00823 PPE family 6 161 1.8E-56 T 28-03-2018 IPR000030 PPE family CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 SUPERFAMILY SSF140459 2 170 9.68E-57 T 28-03-2018 CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 3038 3076 2.8E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1706 1744 2.5E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1940 1977 5.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1518 1556 5.2E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2412 2448 2.0E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2454 2490 3.7E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2887 2924 2.1E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1094 1131 2.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1675 1713 4.7E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 750 789 1.7E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1980 2017 4.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1594 1631 1.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 320 359 1.6E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 219 256 4.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1113 1151 1.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 643 681 5.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2997 3036 5.7E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1665 1704 1.9E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 361 399 2.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 702 738 2.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 199 237 1.4E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1637 1673 2.3E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2492 2531 1.1E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2558 2596 1.5E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 623 661 2.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1083 1121 1.7E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2391 2428 3.4E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 791 829 2.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2023 2059 8.6E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1176 1213 6.6E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2102 2140 4.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2959 2995 3.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1558 1596 7.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1255 1293 8.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2916 2954 9.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 1215 1253 8.4E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2527 2565 3.3E-12 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 659 697 1.5E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 282 318 1.2E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 771 808 5.7E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 2061 2100 5.5E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS01635 884700d3d012d6e9d6efe19412cdc713 3186 Pfam PF01469 Pentapeptide repeats (8 copies) 730 768 4.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Pfam PF00702 haloacid dehalogenase-like hydrolase 454 672 2.5E-52 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Gene3D G3DSA:3.40.1110.10 474 584 9.2E-36 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 231 737 5.8E-92 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 SUPERFAMILY SSF81653 263 358 8.89E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 198 760 4.9E-196 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 658 674 1.9E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 689 714 1.9E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 SUPERFAMILY SSF56784 456 476 3.68E-64 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 SUPERFAMILY SSF56784 515 758 3.68E-64 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 SUPERFAMILY SSF81665 359 450 4.45E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 SUPERFAMILY SSF81665 226 262 4.45E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Gene3D G3DSA:3.40.50.1000 585 722 7.5E-44 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 460 466 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Pfam PF00122 E1-E2 ATPase 260 436 9.8E-55 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 179 761 5.5E-180 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Gene3D G3DSA:3.30.70.100 14 74 9.3E-4 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 472 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 681 693 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 615 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 308 322 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 658 677 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 583 594 1.9E-30 T 28-03-2018 CP478_RS05290 cd85142c7a1d1507d893ff4c246a069d 770 Gene3D G3DSA:1.20.1110.10 217 473 2.6E-49 T 28-03-2018 CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 SUPERFAMILY SSF53686 2 305 4.58E-76 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 Gene3D G3DSA:3.40.50.1100 30 142 6.5E-36 T 28-03-2018 CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 287 9.4E-60 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 Gene3D G3DSA:3.40.50.1100 143 317 1.5E-31 T 28-03-2018 CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 40 58 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CP478_RS07325 2ff49a0e418faed188be3c825d0f92ec 323 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 306 2.5E-110 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Gene3D G3DSA:2.40.30.10 65 156 3.0E-18 T 28-03-2018 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 SUPERFAMILY SSF54292 279 380 2.88E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Gene3D G3DSA:3.40.50.80 161 286 2.0E-20 T 28-03-2018 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Pfam PF00970 Oxidoreductase FAD-binding domain 88 161 5.7E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 307 371 4.2E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00410 Phenol hydroxylase reductase family signature 156 165 9.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00410 Phenol hydroxylase reductase family signature 90 102 9.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00410 Phenol hydroxylase reductase family signature 256 264 9.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00410 Phenol hydroxylase reductase family signature 172 191 9.1E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Pfam PF00175 Oxidoreductase NAD-binding domain 173 266 2.7E-8 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 SUPERFAMILY SSF52343 152 279 1.83E-23 T 28-03-2018 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 172 191 5.0E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 90 100 5.0E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 109 116 5.0E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 Gene3D G3DSA:3.10.20.30 287 380 2.0E-18 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS17720 94a10d6e5e37f5268465f07d7455eb7f 380 SUPERFAMILY SSF63380 57 161 6.24E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS16700 e5188404e71d539dbf610e43b6e7bb28 79 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 7.4E-34 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 CP478_RS16700 e5188404e71d539dbf610e43b6e7bb28 79 Gene3D G3DSA:3.40.30.10 1 79 1.3E-15 T 28-03-2018 CP478_RS16700 e5188404e71d539dbf610e43b6e7bb28 79 Pfam PF00462 Glutaredoxin 3 61 2.3E-15 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CP478_RS16700 e5188404e71d539dbf610e43b6e7bb28 79 SUPERFAMILY SSF52833 1 73 9.38E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 SMART SM00220 14 276 4.1E-59 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 Pfam PF00069 Protein kinase domain 14 268 8.2E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 Gene3D G3DSA:1.10.510.10 98 274 5.0E-41 T 28-03-2018 CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 SUPERFAMILY SSF56112 12 282 6.34E-66 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 SUPERFAMILY SSF56112 323 331 6.34E-66 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 Gene3D G3DSA:3.30.200.20 8 97 1.1E-17 T 28-03-2018 CP478_RS11375 f4a8ec8d5e6ca50949b42179598d638d 589 Pfam PF14032 PknH-like extracellular domain 394 586 1.7E-36 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS15665 a77f18e0ddd35f8abea30572d160ca4e 93 Gene3D G3DSA:3.40.1620.10 1 56 7.5E-15 T 28-03-2018 CP478_RS15665 a77f18e0ddd35f8abea30572d160ca4e 93 SUPERFAMILY SSF143120 1 81 2.62E-21 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS15665 a77f18e0ddd35f8abea30572d160ca4e 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 6.7E-21 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS15665 a77f18e0ddd35f8abea30572d160ca4e 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 2.2E-20 T 28-03-2018 CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 23 765 0.0 T 28-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 Pfam PF09369 Domain of unknown function (DUF1998) 660 738 8.3E-19 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 SMART SM00490 321 402 2.5E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 SUPERFAMILY SSF52540 69 234 7.71E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 SUPERFAMILY SSF52540 266 413 7.71E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 Gene3D G3DSA:3.40.50.300 41 254 3.2E-25 T 28-03-2018 CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 Gene3D G3DSA:3.40.50.300 281 444 1.2E-19 T 28-03-2018 CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 Pfam PF00270 DEAD/DEAH box helicase 62 232 8.7E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 SMART SM00487 55 262 7.0E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS19915 d92deac96dc9b93315e5eaa37489acf7 771 Pfam PF00271 Helicase conserved C-terminal domain 295 402 6.7E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 Gene3D G3DSA:3.40.309.10 275 470 7.4E-64 T 28-03-2018 CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 Gene3D G3DSA:3.40.605.10 9 274 4.2E-76 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 SUPERFAMILY SSF53720 11 485 1.57E-145 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 TIGRFAM TIGR04284 aldehy_Rv0768: aldehyde dehydrogenase, Rv0768 family 9 488 6.6E-288 T 28-03-2018 IPR026460 Aldehyde dehydrogenase, Rv0768 family CP478_RS04180 9116ebe4b9c18ada19fa8b41dee4e60e 489 Pfam PF00171 Aldehyde dehydrogenase family 21 483 4.4E-145 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 4 265 2.9E-102 T 28-03-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 Gene3D G3DSA:3.40.50.720 112 268 8.4E-22 T 28-03-2018 CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 Gene3D G3DSA:3.40.50.10860 1 111 3.8E-34 T 28-03-2018 CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 SUPERFAMILY SSF53223 6 104 2.82E-24 T 28-03-2018 CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 SUPERFAMILY SSF51735 118 265 3.05E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13995 704f349de6e23d9036c30ff5b9637f5e 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 8.8E-18 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CP478_RS06705 09fbdbd6cf7393a6822c0f57397055be 131 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 4 84 8.6E-27 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CP478_RS06705 09fbdbd6cf7393a6822c0f57397055be 131 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 6.2E-11 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CP478_RS06705 09fbdbd6cf7393a6822c0f57397055be 131 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 6.2E-11 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CP478_RS06705 09fbdbd6cf7393a6822c0f57397055be 131 Pfam PF02416 mttA/Hcf106 family 5 48 1.1E-5 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CP478_RS06705 09fbdbd6cf7393a6822c0f57397055be 131 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 129 15.328 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CP478_RS08560 03de6f7a01f8ee4b27e8849ccc2d00aa 765 Pfam PF00128 Alpha amylase, catalytic domain 31 101 1.3E-15 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08560 03de6f7a01f8ee4b27e8849ccc2d00aa 765 SMART SM00642 20 654 6.8E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08560 03de6f7a01f8ee4b27e8849ccc2d00aa 765 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 6 762 2.4E-286 T 28-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CP478_RS08560 03de6f7a01f8ee4b27e8849ccc2d00aa 765 Gene3D G3DSA:3.20.20.80 10 676 2.7E-103 T 28-03-2018 CP478_RS08560 03de6f7a01f8ee4b27e8849ccc2d00aa 765 SUPERFAMILY SSF51445 14 680 2.02E-124 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 Gene3D G3DSA:3.50.50.60 1 439 1.2E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 PIRSF PIRSF000171 1 570 2.3E-41 T 28-03-2018 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 42 51 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.8E-9 T 28-03-2018 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 379 7.8E-9 T 28-03-2018 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 SUPERFAMILY SSF46977 447 581 2.22E-45 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 Pfam PF02910 Fumarate reductase flavoprotein C-term 455 581 1.3E-35 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 Gene3D G3DSA:1.20.58.100 440 535 1.9E-28 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 Pfam PF00890 FAD binding domain 7 394 5.0E-113 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 2 582 0.0 T 28-03-2018 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 SUPERFAMILY SSF56425 226 355 4.93E-37 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 Gene3D G3DSA:4.10.80.40 536 581 3.4E-12 T 28-03-2018 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 SUPERFAMILY SSF51905 358 426 3.56E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 SUPERFAMILY SSF51905 3 243 3.56E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08505 9381a24d7f0c9bbfbbf3919b59a5bdaa 583 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 1.5E-220 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS17320 d0dc8d66f886b838c701a47ac59ee924 320 Gene3D G3DSA:1.10.8.300 204 312 1.0E-29 T 28-03-2018 CP478_RS17320 d0dc8d66f886b838c701a47ac59ee924 320 SUPERFAMILY SSF52540 15 293 1.01E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17320 d0dc8d66f886b838c701a47ac59ee924 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 4.0E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CP478_RS17320 d0dc8d66f886b838c701a47ac59ee924 320 PIRSF PIRSF002849 2 317 8.5E-127 T 28-03-2018 CP478_RS17320 d0dc8d66f886b838c701a47ac59ee924 320 Gene3D G3DSA:3.40.50.300 23 189 1.3E-26 T 28-03-2018 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Gene3D G3DSA:4.10.860.10 638 691 1.5E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SMART SM00490 461 547 6.9E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SMART SM00487 11 426 1.7E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Gene3D G3DSA:3.40.50.300 416 590 1.2E-31 T 28-03-2018 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Pfam PF04851 Type III restriction enzyme, res subunit 18 140 1.7E-8 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SUPERFAMILY SSF52540 35 84 1.1E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SUPERFAMILY SSF52540 460 582 1.1E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SUPERFAMILY SSF46600 644 689 4.18E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Hamap MF_00204 UvrABC system protein B [uvrB]. 5 688 43.258 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Gene3D G3DSA:3.40.50.300 14 415 1.0E-32 T 28-03-2018 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 6 686 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Pfam PF00271 Helicase conserved C-terminal domain 442 545 1.3E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 SUPERFAMILY SSF52540 7 416 1.78E-131 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Pfam PF12344 Ultra-violet resistance protein B 553 594 3.9E-22 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CP478_RS08935 7aac4325f0909e394f084853c886cfdf 698 Pfam PF02151 UvrB/uvrC motif 655 687 3.4E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SMART SM01240 43 515 1.7E-302 T 28-03-2018 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SUPERFAMILY SSF54631 129 239 3.54E-30 T 28-03-2018 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 PIRSF PIRSF000130 35 529 3.7E-201 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 Gene3D G3DSA:3.20.20.70 34 510 1.3E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 Pfam PF00571 CBS domain 129 176 2.7E-9 T 28-03-2018 IPR000644 CBS domain CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 Pfam PF00571 CBS domain 185 238 3.1E-8 T 28-03-2018 IPR000644 CBS domain CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 44 515 1.1E-151 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 331 343 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 44 528 83.655 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SUPERFAMILY SSF51412 38 126 1.22E-112 T 28-03-2018 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SUPERFAMILY SSF51412 252 519 1.22E-112 T 28-03-2018 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 44 497 5.1E-180 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SMART SM00116 132 180 2.7E-7 T 28-03-2018 IPR000644 CBS domain CP478_RS18670 44f1e57aabceca8277d26f091198c852 529 SMART SM00116 193 241 8.8E-8 T 28-03-2018 IPR000644 CBS domain CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 6 290 3.6E-114 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 Gene3D G3DSA:3.40.190.10 96 194 6.8E-36 T 28-03-2018 CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.3E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 Gene3D G3DSA:1.10.10.10 1 87 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 Pfam PF03466 LysR substrate binding domain 97 267 1.6E-10 T 28-03-2018 IPR005119 LysR, substrate-binding CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 SUPERFAMILY SSF46785 5 113 1.02E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10810 ec5706bd0786e938a496939b559d3524 303 SUPERFAMILY SSF53850 95 291 1.55E-19 T 28-03-2018 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 SUPERFAMILY SSF53822 70 334 7.28E-36 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 Pfam PF13377 Periplasmic binding protein-like domain 183 333 5.0E-17 T 28-03-2018 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 Gene3D G3DSA:3.40.50.2300 62 185 5.6E-27 T 28-03-2018 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 53 1.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 Gene3D G3DSA:1.10.260.40 7 61 1.2E-16 T 28-03-2018 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 SMART SM00354 8 79 2.0E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 Gene3D G3DSA:3.40.50.2300 186 335 6.6E-31 T 28-03-2018 CP478_RS19540 7dc0d24920663c3e2a79ac10df02bbd4 359 SUPERFAMILY SSF47413 7 66 4.22E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS17755 a7c09de3de9dc1068f086d49de99797b 160 PIRSF PIRSF005028 1 160 2.1E-59 T 28-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CP478_RS17755 a7c09de3de9dc1068f086d49de99797b 160 SUPERFAMILY SSF116726 89 156 6.28E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS17755 a7c09de3de9dc1068f086d49de99797b 160 Pfam PF02080 TrkA-C domain 90 154 1.0E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS17755 a7c09de3de9dc1068f086d49de99797b 160 Gene3D G3DSA:3.30.70.1450 89 160 3.4E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 7 271 9.1E-98 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 Gene3D G3DSA:3.10.129.10 133 274 3.3E-44 T 28-03-2018 CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 Pfam PF13622 Thioesterase-like superfamily 32 269 3.8E-54 T 28-03-2018 CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 Gene3D G3DSA:3.10.129.10 1 114 2.6E-37 T 28-03-2018 CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 SUPERFAMILY SSF54637 2 112 6.78E-33 T 28-03-2018 IPR029069 HotDog domain CP478_RS14275 463eda25fe4517b1069e68e207bf9a34 281 SUPERFAMILY SSF54637 115 271 1.7E-45 T 28-03-2018 IPR029069 HotDog domain CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 304 4.8E-100 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 PIRSF PIRSF005963 2 311 2.1E-125 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 SMART SM00729 71 276 4.2E-11 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 1.1E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 Pfam PF04055 Radical SAM superfamily 81 232 3.3E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 SUPERFAMILY SSF102114 36 296 1.44E-62 T 28-03-2018 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 141.024 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12050 d8cc24de31674d7d9a92794f99c4bab1 311 Gene3D G3DSA:3.20.20.70 29 299 5.0E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 Gene3D G3DSA:1.20.1290.10 259 342 6.1E-5 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 Gene3D G3DSA:1.20.1290.10 3 131 1.0E-18 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 SUPERFAMILY SSF69118 208 322 2.3E-6 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 SUPERFAMILY SSF69118 2 161 7.33E-21 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 Pfam PF02627 Carboxymuconolactone decarboxylase family 49 121 7.7E-9 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS11745 8b115a466f60778ada5d352accfd3e5a 344 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 61 108 1.5E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 114 132 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 Gene3D G3DSA:1.10.1200.80 276 344 2.0E-19 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 Pfam PF01207 Dihydrouridine synthase (Dus) 25 337 1.3E-110 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 SUPERFAMILY SSF51395 23 340 1.63E-76 T 28-03-2018 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 PIRSF PIRSF006621 12 353 3.9E-118 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 15 344 1.3E-131 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CP478_RS04465 eead528c6260e96cf60997fa608d6964 389 Gene3D G3DSA:3.20.20.70 19 265 2.6E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 SUPERFAMILY SSF52518 868 1086 2.94E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 SMART SM00861 880 1079 2.2E-47 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 5 37 6.8E-11 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Pfam PF02779 Transketolase, pyrimidine binding domain 879 1080 2.4E-53 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Gene3D G3DSA:1.10.287.1150 362 447 1.5E-23 T 28-03-2018 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 358 1229 2.6E-297 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 103 335 5.0E-55 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 PIRSF PIRSF000157 1 1231 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Gene3D G3DSA:3.40.50.970 448 815 9.5E-92 T 28-03-2018 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Gene3D G3DSA:3.30.559.10 85 337 2.4E-50 T 28-03-2018 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Pfam PF00676 Dehydrogenase E1 component 489 817 4.3E-56 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1084 1230 1.6E-40 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 SUPERFAMILY SSF52518 403 816 3.53E-83 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 Gene3D G3DSA:3.40.50.970 876 1092 6.2E-52 T 28-03-2018 CP478_RS06835 c793ed3c1a93a89a34f9d114d8d355e2 1231 SUPERFAMILY SSF52777 94 335 1.16E-52 T 28-03-2018 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.355 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.6E-34 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CP478_RS03800 94bca9307156357f176770f87623b1c1 101 SUPERFAMILY SSF54999 5 100 2.62E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CP478_RS03800 94bca9307156357f176770f87623b1c1 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 8.3E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03800 94bca9307156357f176770f87623b1c1 101 Gene3D G3DSA:3.30.70.600 4 101 8.7E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CP478_RS03800 94bca9307156357f176770f87623b1c1 101 SMART SM01403 7 101 2.0E-54 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CP478_RS19135 38b312532cede0635138939b5758ccc2 400 Pfam PF02470 MlaD protein 41 117 2.5E-14 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS19135 38b312532cede0635138939b5758ccc2 400 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 298 2.6E-81 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19135 38b312532cede0635138939b5758ccc2 400 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 146 389 1.0E-49 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS08300 40564fa50d94427f5190c5eb544ad401 243 Pfam PF05050 Methyltransferase FkbM domain 45 215 9.7E-18 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS08300 40564fa50d94427f5190c5eb544ad401 243 Gene3D G3DSA:3.40.50.150 27 225 7.1E-25 T 28-03-2018 CP478_RS08300 40564fa50d94427f5190c5eb544ad401 243 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 43 190 3.6E-29 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS08300 40564fa50d94427f5190c5eb544ad401 243 SUPERFAMILY SSF53335 4 216 1.8E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 SUPERFAMILY SSF51735 1 151 8.69E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 297 3.0E-136 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 Gene3D G3DSA:3.40.50.720 1 139 1.1E-14 T 28-03-2018 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 SUPERFAMILY SSF55347 127 272 3.99E-58 T 28-03-2018 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 303 143.311 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 127 272 1.1E-62 T 28-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 117 9.9E-10 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 PIRSF PIRSF015689 1 302 3.6E-138 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 Gene3D G3DSA:3.30.360.10 140 272 4.3E-67 T 28-03-2018 CP478_RS19325 a3e5ebbe17d28c32a000fd9cbfe1369a 303 SMART SM00859 6 119 1.1E-7 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Gene3D G3DSA:3.30.565.10 22 259 3.7E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 675 1.2E-300 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 SUPERFAMILY SSF55874 12 214 1.96E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 SUPERFAMILY SSF56719 429 670 7.06E-81 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Pfam PF01751 Toprim domain 454 564 6.6E-16 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 SUPERFAMILY SSF54211 256 426 1.48E-60 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 177 6.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 SMART SM00387 37 179 5.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 675 98.978 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Gene3D G3DSA:3.40.50.670 437 672 4.3E-95 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Pfam PF00204 DNA gyrase B 256 425 7.5E-64 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 606 663 1.0E-25 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 539 556 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 76 89 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 118 132 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 455 469 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 303 316 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 607 623 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 559 571 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 521 537 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR00418 DNA topoisomerase II family signature 41 56 4.1E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 SMART SM00433 41 668 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 Gene3D G3DSA:3.30.230.10 260 427 1.0E-64 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 ProSitePatterns PS00177 DNA topoisomerase II signature. 457 465 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 12 22 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 628 640 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 199 212 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 347 363 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 255 277 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 409 429 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 644 660 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 395 409 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 184 199 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS00025 1f029391f0a0252dcd6048e2560c3f7b 675 PRINTS PR01159 DNA gyrase subunit B signature 505 514 2.6E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CP478_RS09920 da44a41108d95520c2e6dee4ae149831 209 PIRSF PIRSF000847 8 196 2.2E-48 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CP478_RS09920 da44a41108d95520c2e6dee4ae149831 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 55 77 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS09920 da44a41108d95520c2e6dee4ae149831 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 77 1.3E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS09610 75a1254a097cbb208c32a2efc1c114e5 365 Pfam PF02720 Domain of unknown function (DUF222) 22 306 1.3E-73 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS09610 75a1254a097cbb208c32a2efc1c114e5 365 Pfam PF01844 HNH endonuclease 314 352 2.4E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CP478_RS09610 75a1254a097cbb208c32a2efc1c114e5 365 SMART SM00507 297 348 2.5E-13 T 28-03-2018 IPR003615 HNH nuclease CP478_RS09610 75a1254a097cbb208c32a2efc1c114e5 365 Gene3D G3DSA:3.40.1800.10 288 361 1.0E-10 T 28-03-2018 CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 199 0.0029 T 28-03-2018 CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 Gene3D G3DSA:3.40.50.720 2 279 2.6E-57 T 28-03-2018 CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 Pfam PF00106 short chain dehydrogenase 15 203 8.9E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 5.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 5.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16725 26d56d45e20175f403068d5a2cb595c8 287 SUPERFAMILY SSF51735 10 277 3.23E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11685 419a9acf64e6e76162ca794eebe156d1 241 Hamap MF_01197 Cell division protein SepF [sepF]. 24 232 21.179 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CP478_RS11685 419a9acf64e6e76162ca794eebe156d1 241 Pfam PF04472 Cell division protein SepF 153 224 4.2E-24 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Gene3D G3DSA:1.10.601.10 1 364 1.4E-79 T 28-03-2018 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Pfam PF04545 Sigma-70, region 4 463 516 1.1E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 PRINTS PR00046 Major sigma-70 factor signature 319 332 4.7E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 PRINTS PR00046 Major sigma-70 factor signature 503 514 4.7E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 PRINTS PR00046 Major sigma-70 factor signature 467 479 4.7E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 PRINTS PR00046 Major sigma-70 factor signature 488 503 4.7E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 PRINTS PR00046 Major sigma-70 factor signature 343 351 4.7E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 110 528 35.329 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Pfam PF04539 Sigma-70 region 3 374 449 1.9E-28 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Pfam PF00140 Sigma-70 factor, region 1.2 226 259 4.7E-16 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 291 516 1.1E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Gene3D G3DSA:1.10.10.10 457 528 3.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 SUPERFAMILY SSF88659 368 441 2.13E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 488 514 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 SUPERFAMILY SSF88659 427 527 1.81E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Gene3D G3DSA:1.10.10.10 365 415 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 319 332 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 SUPERFAMILY SSF88946 223 365 7.29E-54 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 Pfam PF04542 Sigma-70 region 2 295 364 2.0E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14820 e06975e0c4909a4eb9ce6a48dfe7f347 528 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 291 527 1.0E-113 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 Pfam PF00464 Serine hydroxymethyltransferase 9 390 2.6E-159 T 28-03-2018 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 420 49.374 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 Gene3D G3DSA:3.90.1150.10 275 419 1.6E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 PIRSF PIRSF000412 1 425 3.1E-158 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 SUPERFAMILY SSF53383 3 422 1.17E-168 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS00390 774f3fca0edfda969da405cd0722b263 425 Gene3D G3DSA:3.40.640.10 37 274 6.8E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 SUPERFAMILY SSF82679 48 151 1.83E-35 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 PRINTS PR00338 Transcription termination factor NUSG signature 214 230 5.7E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 PRINTS PR00338 Transcription termination factor NUSG signature 196 211 5.7E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 PRINTS PR00338 Transcription termination factor NUSG signature 101 113 5.7E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 46 238 23.249 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 ProSitePatterns PS01014 Transcription termination factor nusG signature. 221 230 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 Gene3D G3DSA:3.30.70.940 47 153 1.1E-35 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 49 238 2.8E-67 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 Pfam PF02357 Transcription termination factor nusG 48 150 1.7E-24 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 SMART SM00738 46 154 1.1E-48 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 Gene3D G3DSA:2.30.30.30 180 238 1.5E-18 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CP478_RS03455 5312268cea851e4a1e43578b726df24c 238 SUPERFAMILY SSF50104 182 238 1.1E-16 T 28-03-2018 IPR008991 Translation protein SH3-like domain CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Pfam PF00175 Oxidoreductase NAD-binding domain 112 202 3.6E-5 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 263 271 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Gene3D G3DSA:3.10.20.30 212 309 1.4E-11 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 236 300 6.5E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 SUPERFAMILY SSF52343 97 223 1.18E-24 T 28-03-2018 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Gene3D G3DSA:2.40.30.10 1 100 1.9E-17 T 28-03-2018 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Gene3D G3DSA:3.40.50.80 101 211 8.0E-17 T 28-03-2018 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 SUPERFAMILY SSF54292 211 307 9.7E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 89 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 89 103 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 29 39 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 39 51 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 2.9E-28 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 Pfam PF00970 Oxidoreductase FAD-binding domain 7 101 5.4E-5 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS15205 04ab43899b2faf0a8d30d8dffcc04ace 309 SUPERFAMILY SSF63380 3 99 1.79E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 Pfam PF00107 Zinc-binding dehydrogenase 197 327 8.8E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 370 3.5E-176 T 28-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 SUPERFAMILY SSF50129 2 181 1.83E-58 T 28-03-2018 IPR011032 GroES-like CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 SUPERFAMILY SSF51735 158 337 3.13E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 Gene3D G3DSA:3.90.180.10 4 181 1.9E-47 T 28-03-2018 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 SUPERFAMILY SSF50129 321 370 1.07E-10 T 28-03-2018 IPR011032 GroES-like CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 Gene3D G3DSA:3.40.50.10730 182 311 9.1E-19 T 28-03-2018 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 155 8.4E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS04145 e5e5f8d1da7b0126da40dc74d61d0723 375 SMART SM00829 5 368 2.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 SUPERFAMILY SSF52467 167 366 6.76E-38 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 SUPERFAMILY SSF52518 371 561 4.27E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 182 2.7E-48 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 206 335 3.8E-31 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 552 3.8E-26 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 12 570 8.4E-279 T 28-03-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Gene3D G3DSA:3.40.50.970 8 196 6.0E-46 T 28-03-2018 CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Gene3D G3DSA:3.40.50.1220 197 355 1.1E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 SUPERFAMILY SSF52518 14 189 2.54E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS00650 f020175c4e50b54ab7afb4a59f369067 582 Gene3D G3DSA:3.40.50.970 356 575 3.7E-37 T 28-03-2018 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 Gene3D G3DSA:1.10.760.10 153 243 7.2E-15 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 SUPERFAMILY SSF46626 144 236 7.42E-25 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 PIRSF PIRSF000007 1 280 4.3E-147 T 28-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 163 235 1.4E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 Gene3D G3DSA:1.10.760.10 39 152 1.1E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 SUPERFAMILY SSF46626 28 142 1.49E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS11930 94e9a9f1cf9fcb096181913c2caaa680 280 Pfam PF00034 Cytochrome c 64 137 3.4E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CP478_RS08720 d9487f2c44522e524b86e8bc89cadcde 236 Pfam PF00293 NUDIX domain 32 136 2.1E-8 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS08720 d9487f2c44522e524b86e8bc89cadcde 236 SUPERFAMILY SSF46785 152 224 1.47E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08720 d9487f2c44522e524b86e8bc89cadcde 236 SUPERFAMILY SSF55811 28 148 1.11E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS08720 d9487f2c44522e524b86e8bc89cadcde 236 Gene3D G3DSA:1.10.10.10 160 228 8.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08720 d9487f2c44522e524b86e8bc89cadcde 236 Gene3D G3DSA:3.90.79.10 11 159 2.4E-25 T 28-03-2018 CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 SUPERFAMILY SSF54631 204 343 1.39E-23 T 28-03-2018 CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 SMART SM00116 227 275 3.4 T 28-03-2018 IPR000644 CBS domain CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 SMART SM00116 288 336 0.16 T 28-03-2018 IPR000644 CBS domain CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 Gene3D G3DSA:3.10.580.10 194 345 3.5E-28 T 28-03-2018 CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 Pfam PF00571 CBS domain 242 272 1.1E-4 T 28-03-2018 IPR000644 CBS domain CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 Pfam PF00571 CBS domain 286 334 6.8E-6 T 28-03-2018 IPR000644 CBS domain CP478_RS10015 c43fe082f514e9f621183132c7f7228c 345 Pfam PF01595 Domain of unknown function DUF21 8 198 7.3E-39 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CP478_RS15050 9869575771b793363b34c2f3aca55ad1 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 76 98 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS15050 9869575771b793363b34c2f3aca55ad1 209 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 28 199 4.6E-39 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CP478_RS15050 9869575771b793363b34c2f3aca55ad1 209 PIRSF PIRSF000847 24 206 6.4E-44 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CP478_RS15050 9869575771b793363b34c2f3aca55ad1 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 98 1.1E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 Gene3D G3DSA:1.10.10.10 1 83 5.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 SUPERFAMILY SSF46785 1 109 2.04E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 SUPERFAMILY SSF53850 89 292 1.19E-19 T 28-03-2018 CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 Pfam PF03466 LysR substrate binding domain 88 291 1.2E-22 T 28-03-2018 IPR005119 LysR, substrate-binding CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 Gene3D G3DSA:3.40.190.10 84 205 9.0E-13 T 28-03-2018 CP478_RS02010 1d2dacd0b124c5b645ce244ef757420d 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 9.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 PIRSF PIRSF039102 8 370 5.9E-108 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 SUPERFAMILY SSF56059 151 367 3.89E-55 T 28-03-2018 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 SUPERFAMILY SSF52440 10 150 1.63E-35 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Gene3D G3DSA:3.30.470.20 221 371 1.9E-41 T 28-03-2018 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Gene3D G3DSA:3.40.50.20 1 146 4.5E-47 T 28-03-2018 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Gene3D G3DSA:3.30.1490.20 147 220 4.1E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 118 129 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Pfam PF07478 D-ala D-ala ligase C-terminus 158 363 1.7E-73 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 309 336 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 11 366 41.241 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 12 365 4.4E-116 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS16300 99b088bd93a6218f6808aa00c85b3a73 373 Pfam PF01820 D-ala D-ala ligase N-terminus 12 140 2.2E-30 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.366.10 553 684 4.8E-33 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF08659 KR domain 1772 1950 3.7E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00823 Phosphopantetheine attachment site 2047 2113 1.0E-13 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1772 1951 2.1E-47 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF51735 1202 1410 9.05E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:1.10.1200.10 2028 2118 3.2E-14 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1453 1519 1.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.50.720 1764 2000 3.4E-43 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF55048 676 741 1.83E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.90.180.10 1678 1752 0.33 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF53901 23 394 1.31E-93 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.366.10 728 850 4.7E-25 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.90.180.10 1412 1562 2.2E-33 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.30.70.250 685 727 6.2E-9 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 282 395 1.0E-34 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF51735 1770 2010 2.23E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.50.720 1563 1677 5.8E-25 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 513 1.1E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 850 3.6E-85 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF51735 1542 1709 4.69E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.47.10 18 286 1.9E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00825 Beta-ketoacyl synthase 27 450 2.9E-182 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF00698 Acyl transferase domain 553 869 9.0E-97 T 28-03-2018 IPR014043 Acyl transferase CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF47336 2037 2122 9.55E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.40.47.10 289 448 5.1E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF50129 1431 1566 2.04E-30 T 28-03-2018 IPR011032 GroES-like CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF00107 Zinc-binding dehydrogenase 1577 1667 6.8E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00826 914 1077 5.7E-40 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 26 274 1.4E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 187 203 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF14765 Polyketide synthase dehydratase 914 1189 2.3E-49 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Gene3D G3DSA:3.10.129.10 925 1036 2.6E-7 T 28-03-2018 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 Pfam PF00550 Phosphopantetheine attachment site 2045 2109 9.2E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF52151 742 840 9.68E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SUPERFAMILY SSF52151 553 677 9.68E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2070 2085 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS20890 d3c301aea3a0d4e9c88d40857fc5f66a 2126 SMART SM00829 1436 1748 4.9E-160 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS07775 d7b072880e851f78d023f0f39d34ccb3 301 SUPERFAMILY SSF52540 19 168 2.07E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07775 d7b072880e851f78d023f0f39d34ccb3 301 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 17 300 40.276 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CP478_RS07775 d7b072880e851f78d023f0f39d34ccb3 301 Gene3D G3DSA:3.40.50.300 9 173 1.3E-9 T 28-03-2018 CP478_RS07775 d7b072880e851f78d023f0f39d34ccb3 301 PIRSF PIRSF005052 17 301 1.9E-114 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CP478_RS07775 d7b072880e851f78d023f0f39d34ccb3 301 Pfam PF03668 P-loop ATPase protein family 17 301 4.4E-140 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Gene3D G3DSA:2.30.38.10 353 437 5.8E-28 T 28-03-2018 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Gene3D G3DSA:3.40.50.980 24 199 5.9E-42 T 28-03-2018 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Gene3D G3DSA:3.40.50.980 200 352 1.5E-50 T 28-03-2018 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Pfam PF00501 AMP-binding enzyme 34 444 1.6E-111 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 SUPERFAMILY SSF56801 21 541 3.14E-156 T 28-03-2018 CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 529 3.1E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS13695 05fbbeedb1d13699b918e17466eddd71 547 Gene3D G3DSA:3.30.300.30 438 547 1.4E-26 T 28-03-2018 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 490 51.853 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 7 488 5.5E-262 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 SUPERFAMILY SSF51905 163 324 8.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 SUPERFAMILY SSF51905 6 97 8.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 Gene3D G3DSA:3.50.50.60 3 443 1.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15590 6b9de5fe5883bbc6653b560d8a8b1957 493 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 6 490 8.6E-209 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CP478_RS15175 80f5ab0572dcad3d9eaf97c7f4f5d7b5 382 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 301 378 1.2E-16 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS15175 80f5ab0572dcad3d9eaf97c7f4f5d7b5 382 SUPERFAMILY SSF140459 2 173 3.92E-58 T 28-03-2018 CP478_RS15175 80f5ab0572dcad3d9eaf97c7f4f5d7b5 382 Pfam PF00823 PPE family 5 161 3.1E-55 T 28-03-2018 IPR000030 PPE family CP478_RS08065 986de5b84e9e6c734e005cbf1e6e1424 285 SUPERFAMILY SSF52096 15 283 7.03E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS08065 986de5b84e9e6c734e005cbf1e6e1424 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS08065 986de5b84e9e6c734e005cbf1e6e1424 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 283 7.9E-47 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS08065 986de5b84e9e6c734e005cbf1e6e1424 285 Gene3D G3DSA:3.90.226.10 20 239 1.3E-55 T 28-03-2018 CP478_RS08065 986de5b84e9e6c734e005cbf1e6e1424 285 Gene3D G3DSA:1.10.12.10 240 285 1.1E-7 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:3.40.50.980 701 859 3.9E-34 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:2.30.38.10 864 941 4.6E-24 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF52777 98 266 5.78E-20 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF13193 AMP-binding enzyme C-terminal domain 959 1031 1.2E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:3.30.300.30 947 1068 4.2E-29 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF47336 1055 1131 1.18E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:1.10.1200.10 1069 1145 7.9E-19 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:1.10.1200.10 2 82 3.9E-11 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:3.40.50.1820 1170 1412 6.5E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF00501 AMP-binding enzyme 558 950 2.8E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:3.40.50.980 549 700 1.2E-36 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SMART SM00823 Phosphopantetheine attachment site 8 78 0.4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SMART SM00823 Phosphopantetheine attachment site 1063 1135 4.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF52777 281 522 4.89E-42 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 579 974 2.5E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF56801 551 1075 8.11E-133 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Gene3D G3DSA:3.30.559.10 83 295 9.1E-22 T 28-03-2018 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF00975 Thioesterase domain 1190 1411 1.2E-56 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1089 1104 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF47336 8 112 5.23E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 ProSitePatterns PS00455 Putative AMP-binding domain signature. 695 706 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF00550 Phosphopantetheine attachment site 1065 1131 5.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF00550 Phosphopantetheine attachment site 11 74 6.2E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 Pfam PF00668 Condensation domain 100 442 1.2E-26 T 28-03-2018 IPR001242 Condensation domain CP478_RS12990 f65ee355affcc88b9c6d5131080d912d 1414 SUPERFAMILY SSF53474 1167 1410 1.44E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 SUPERFAMILY SSF51905 161 298 3.84E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 SUPERFAMILY SSF51905 11 133 3.84E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 SUPERFAMILY SSF51905 423 485 3.84E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 SUPERFAMILY SSF56425 296 424 5.86E-26 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 Pfam PF00890 FAD binding domain 22 452 3.3E-51 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 455 1.9E-5 T 28-03-2018 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 1.9E-5 T 28-03-2018 CP478_RS09895 89dafd114679eb4a162f13d4f92e6ade 487 Gene3D G3DSA:3.50.50.60 7 484 2.1E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 SUPERFAMILY SSF46609 3 88 5.5E-30 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 Gene3D G3DSA:1.10.287.990 21 84 6.2E-18 T 28-03-2018 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PIRSF PIRSF000349 1 203 1.0E-74 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.2E-30 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 SUPERFAMILY SSF54719 84 198 2.1E-43 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.8E-20 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.8E-20 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 1.8E-20 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.8E-20 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 1.8E-20 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21025 d24e044fcdc46ed1d41e9e88ef663b45 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 9.8E-34 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CP478_RS21170 9a3ee1f1a47ce1cff8f53f049533de1c 98 Gene3D G3DSA:1.10.287.1060 10 98 3.8E-5 T 28-03-2018 CP478_RS21170 9a3ee1f1a47ce1cff8f53f049533de1c 98 Pfam PF00934 PE family 1 90 8.3E-13 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS21170 9a3ee1f1a47ce1cff8f53f049533de1c 98 SUPERFAMILY SSF140459 26 71 2.33E-6 T 28-03-2018 CP478_RS17105 e18458d372ea2231abf70de22053b78b 391 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 293 387 5.7E-11 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS17105 e18458d372ea2231abf70de22053b78b 391 Pfam PF00823 PPE family 7 163 1.6E-59 T 28-03-2018 IPR000030 PPE family CP478_RS17105 e18458d372ea2231abf70de22053b78b 391 Gene3D G3DSA:1.10.287.1060 24 112 5.4E-6 T 28-03-2018 CP478_RS17105 e18458d372ea2231abf70de22053b78b 391 SUPERFAMILY SSF140459 5 175 1.33E-60 T 28-03-2018 CP478_RS00905 2cbbebc32c234f4e824ff701dcb35da8 161 Gene3D G3DSA:3.30.530.20 16 161 1.2E-21 T 28-03-2018 IPR023393 START-like domain CP478_RS00905 2cbbebc32c234f4e824ff701dcb35da8 161 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 25 152 8.0E-13 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CP478_RS00905 2cbbebc32c234f4e824ff701dcb35da8 161 SUPERFAMILY SSF55961 16 159 1.71E-23 T 28-03-2018 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Gene3D G3DSA:1.10.3710.10 359 452 1.8E-28 T 28-03-2018 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Gene3D G3DSA:1.10.8.60 169 257 3.1E-18 T 28-03-2018 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 SUPERFAMILY SSF48019 263 446 2.04E-71 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 SUPERFAMILY SSF52540 26 247 1.52E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Pfam PF12002 MgsA AAA+ ATPase C terminal 278 443 9.7E-68 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Gene3D G3DSA:3.40.50.300 21 168 1.6E-23 T 28-03-2018 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 SMART SM00382 64 180 6.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Gene3D G3DSA:1.20.272.10 262 356 3.7E-38 T 28-03-2018 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 68 161 1.5E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS14030 79bb063519ca03d81ec4074c35fdb9c4 452 Pfam PF16193 AAA C-terminal domain 202 277 1.4E-26 T 28-03-2018 IPR032423 AAA C-terminal domain CP478_RS13280 bb04bfb4edd81abb4fa23a364ff2e4b9 99 Gene3D G3DSA:1.10.287.1060 1 99 9.7E-9 T 28-03-2018 CP478_RS13280 bb04bfb4edd81abb4fa23a364ff2e4b9 99 SUPERFAMILY SSF140459 8 84 4.18E-16 T 28-03-2018 CP478_RS13280 bb04bfb4edd81abb4fa23a364ff2e4b9 99 Pfam PF00934 PE family 1 92 4.3E-24 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00365 904e6a371a030876d888ce759a99963c 133 Pfam PF01850 PIN domain 5 122 8.0E-6 T 28-03-2018 IPR002716 PIN domain CP478_RS00365 904e6a371a030876d888ce759a99963c 133 Gene3D G3DSA:3.40.50.1010 2 133 1.3E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS00365 904e6a371a030876d888ce759a99963c 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 12.694 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS00365 904e6a371a030876d888ce759a99963c 133 SUPERFAMILY SSF88723 4 125 1.37E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06730 7d07602c85dc0ce57deef1c28e7f19e7 57 Gene3D G3DSA:3.40.1620.10 6 48 8.3E-9 T 28-03-2018 CP478_RS06730 7d07602c85dc0ce57deef1c28e7f19e7 57 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 46 6.6E-6 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS06730 7d07602c85dc0ce57deef1c28e7f19e7 57 SUPERFAMILY SSF143120 6 46 2.35E-5 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 SUPERFAMILY SSF56059 129 340 1.94E-37 T 28-03-2018 CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 SUPERFAMILY SSF52440 24 127 1.12E-17 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 Gene3D G3DSA:3.30.470.20 222 418 4.2E-19 T 28-03-2018 CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 Gene3D G3DSA:3.30.1490.20 133 221 4.2E-11 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 Gene3D G3DSA:3.40.50.20 20 132 6.7E-14 T 28-03-2018 CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 27 414 8.5E-158 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CP478_RS02070 da2f62e4b911aee0c93e46fa953b370c 419 Pfam PF02222 ATP-grasp domain 139 319 4.4E-22 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CP478_RS10785 6dfb240e1ff26e877df8cba5152e7854 139 Pfam PF01850 PIN domain 1 125 4.7E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS10785 6dfb240e1ff26e877df8cba5152e7854 139 Gene3D G3DSA:3.40.50.1010 1 132 2.0E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10785 6dfb240e1ff26e877df8cba5152e7854 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 132 15.124 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS10785 6dfb240e1ff26e877df8cba5152e7854 139 SUPERFAMILY SSF88723 1 127 2.45E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 PRINTS PR00419 Adrenodoxin reductase family signature 78 88 2.8E-12 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 PRINTS PR00419 Adrenodoxin reductase family signature 150 164 2.8E-12 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 2.8E-12 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 PIRSF PIRSF000362 1 455 2.7E-165 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 166 6.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 Gene3D G3DSA:3.40.50.720 1 104 4.1E-7 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 SUPERFAMILY SSF51971 3 216 3.41E-59 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 SUPERFAMILY SSF51971 264 324 3.41E-59 T 28-03-2018 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 Gene3D G3DSA:3.50.50.60 105 324 3.4E-76 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17000 9785624c7c2f494d0d9c4b99a39ed0a6 456 SUPERFAMILY SSF51971 308 444 7.06E-12 T 28-03-2018 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Gene3D G3DSA:3.40.50.1220 188 340 1.4E-29 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 336 4.3E-26 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 537 2.0E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 172 4.6E-44 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Gene3D G3DSA:3.40.50.970 1 184 1.5E-40 T 28-03-2018 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 SUPERFAMILY SSF52467 157 338 1.13E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 Gene3D G3DSA:3.40.50.970 354 544 4.2E-38 T 28-03-2018 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 SUPERFAMILY SSF52518 368 546 1.3E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS18990 8a77247bdf484d74923604806dc09af1 552 SUPERFAMILY SSF52518 2 173 9.82E-36 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS07510 2b08c35e2f45dccd7e61470c7993625e 261 SUPERFAMILY SSF89392 54 256 1.96E-48 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CP478_RS07510 2b08c35e2f45dccd7e61470c7993625e 261 Gene3D G3DSA:3.40.190.10 21 258 1.1E-4 T 28-03-2018 CP478_RS07510 2b08c35e2f45dccd7e61470c7993625e 261 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 22 256 5.0E-119 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS07510 2b08c35e2f45dccd7e61470c7993625e 261 Pfam PF07161 LppX_LprAFG lipoprotein 57 256 8.4E-70 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS15765 fc03b09989106311594188d415e23b89 252 SMART SM00862 159 233 2.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS15765 fc03b09989106311594188d415e23b89 252 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 232 3.0E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS15765 fc03b09989106311594188d415e23b89 252 Gene3D G3DSA:1.10.10.10 124 239 8.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15765 fc03b09989106311594188d415e23b89 252 SUPERFAMILY SSF46894 135 232 4.82E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00826 928 1093 7.5E-39 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 424 520 8.0E-8 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF53901 32 157 1.31E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF53901 184 411 1.31E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.30.70.250 707 751 7.0E-11 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF08659 KR domain 1802 1980 1.1E-61 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00829 1467 1778 5.5E-157 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF47336 2073 2156 1.83E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:1.10.1200.10 2054 2146 3.8E-17 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2100 2115 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF50129 1461 1596 6.92E-29 T 28-03-2018 IPR011032 GroES-like CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF51735 1801 2033 3.46E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00825 Beta-ketoacyl synthase 37 465 1.6E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.90.180.10 1450 1597 2.2E-35 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1802 1981 2.5E-38 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.47.10 303 463 4.0E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.366.10 752 875 1.7E-17 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF51735 1572 1738 4.25E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1485 1544 1.2E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 288 1.3E-94 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.47.10 27 299 7.9E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF00698 Acyl transferase domain 572 890 7.0E-103 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF55048 694 757 9.94E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.90.180.10 1708 1782 4.7E-7 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 412 4.5E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF00550 Phosphopantetheine attachment site 2078 2140 7.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF13602 Zinc-binding dehydrogenase 1639 1778 5.3E-23 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 201 217 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00823 Phosphopantetheine attachment site 2075 2145 1.6E-19 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Pfam PF14765 Polyketide synthase dehydratase 928 1219 3.2E-51 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.50.720 1798 2048 3.8E-43 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.50.720 1598 1707 8.4E-22 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.10.129.10 933 1049 2.7E-10 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF51735 1226 1431 2.36E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 Gene3D G3DSA:3.40.366.10 570 706 2.7E-33 T 28-03-2018 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 574 872 1.4E-83 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF52151 571 696 3.14E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16025 ba24954d8d5c6db42725e356fe600297 2188 SUPERFAMILY SSF52151 759 855 3.14E-54 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 SMART SM01232 10 97 1.4E-23 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 SUPERFAMILY SSF46946 10 90 5.63E-20 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 11 91 5.8E-17 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 Pfam PF06827 Zinc finger found in FPG and IleRS 115 142 8.6E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 SUPERFAMILY SSF57716 101 143 3.14E-11 T 28-03-2018 CP478_RS05145 e125a48e7fcc98a668327152e34c0da4 158 Gene3D G3DSA:1.10.8.50 10 153 1.9E-34 T 28-03-2018 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Gene3D G3DSA:3.30.300.30 439 542 5.4E-25 T 28-03-2018 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 527 3.8E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Gene3D G3DSA:2.30.38.10 366 438 1.9E-21 T 28-03-2018 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Pfam PF00501 AMP-binding enzyme 32 444 5.1E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Gene3D G3DSA:3.40.50.980 24 195 9.3E-31 T 28-03-2018 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 Gene3D G3DSA:3.40.50.980 196 357 1.7E-37 T 28-03-2018 CP478_RS00655 e9d86286a54c25c1e563d4c978091d38 542 SUPERFAMILY SSF56801 25 538 1.23E-124 T 28-03-2018 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 185 3.6E-28 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 416 2.2E-104 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 SUPERFAMILY SSF52518 352 519 1.41E-15 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 Gene3D G3DSA:3.40.50.970 326 554 3.1E-21 T 28-03-2018 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 Gene3D G3DSA:3.40.50.970 1 198 3.5E-53 T 28-03-2018 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 SUPERFAMILY SSF52518 5 197 3.21E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 554 30.228 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CP478_RS02970 2bdea05fcdf24ae1cf58ffdb92f3abcc 554 PIRSF PIRSF004983 1 554 2.6E-152 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 Gene3D G3DSA:3.30.1490.10 76 131 1.0E-19 T 28-03-2018 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 Gene3D G3DSA:3.30.1370.30 1 67 2.4E-26 T 28-03-2018 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.516 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 SUPERFAMILY SSF56047 3 132 5.49E-45 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03890 4affcf3623e8dbc26753fdf8dc041544 132 Pfam PF00410 Ribosomal protein S8 5 132 1.2E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 287 375 1.9E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 SMART SM00855 284 444 4.0E-7 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 Pfam PF00934 PE family 1 92 1.2E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 SUPERFAMILY SSF140459 9 84 1.83E-21 T 28-03-2018 CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 Gene3D G3DSA:3.40.50.1240 278 505 1.2E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS04100 fa1585e12c3b1c4998ccfd9beced79d4 584 SUPERFAMILY SSF53254 285 498 1.84E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 560 1.6E-35 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 SMART SM00663 310 589 5.8E-173 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Gene3D G3DSA:2.40.40.20 421 563 5.8E-40 T 28-03-2018 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 736 4.2E-27 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1278 17.398 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 SUPERFAMILY SSF64484 5 1268 0.0 T 28-03-2018 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Gene3D G3DSA:2.40.50.100 987 1116 2.2E-33 T 28-03-2018 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Pfam PF05000 RNA polymerase Rpb1, domain 4 754 828 6.2E-8 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1268 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 2.4E-82 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03605 ee7ce7f7c3eb03de4010ed72f5c07ffd 1316 Pfam PF04998 RNA polymerase Rpb1, domain 5 843 1216 7.5E-64 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 Gene3D G3DSA:3.30.565.10 1 232 2.1E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 166 1.2E-12 T 28-03-2018 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 26 35 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 644 30.246 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PIRSF PIRSF002583 1 646 3.9E-224 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 SUPERFAMILY SSF110942 525 643 5.36E-33 T 28-03-2018 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 SMART SM00387 28 185 1.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 SUPERFAMILY SSF55874 5 220 5.89E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 27 49 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 123 145 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 196 214 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 6 26 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 76 93 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 173 190 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 PRINTS PR00775 90kDa heat shock protein signature 94 111 2.0E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 Pfam PF00183 Hsp90 protein 235 645 3.6E-135 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CP478_RS12490 f57543b3006ccfd0e4fa36fb9b5ebda1 647 SUPERFAMILY SSF54211 247 500 8.34E-94 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Gene3D G3DSA:3.40.50.970 4 188 6.9E-41 T 28-03-2018 CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Gene3D G3DSA:3.40.50.1220 189 339 2.3E-22 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 SUPERFAMILY SSF52518 362 541 1.09E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 SUPERFAMILY SSF52467 192 346 3.71E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 SUPERFAMILY SSF52518 10 174 1.18E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 532 1.9E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 172 4.6E-45 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 326 2.4E-19 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CP478_RS09910 59161dd5338a542aa7fee14c45c01243 547 Gene3D G3DSA:3.40.50.970 340 547 1.7E-38 T 28-03-2018 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 187 371 2.7E-20 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 Pfam PF00355 Rieske [2Fe-2S] domain 52 136 3.2E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 Gene3D G3DSA:2.102.10.10 44 153 4.1E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 SUPERFAMILY SSF50022 20 166 3.8E-45 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 88 108 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 37 62 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 150 176 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 109 129 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 67 82 1.9E-25 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 Gene3D G3DSA:3.90.380.10 154 377 6.9E-40 T 28-03-2018 CP478_RS17305 7332a21884832e131feda6b260eb52b5 382 SUPERFAMILY SSF55961 167 368 2.35E-29 T 28-03-2018 CP478_RS11730 7606856c259b791fa04eaea176094419 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 350 22.833 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11730 7606856c259b791fa04eaea176094419 359 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11730 7606856c259b791fa04eaea176094419 359 ProSitePatterns PS01348 MraY family signature 2. 179 190 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11730 7606856c259b791fa04eaea176094419 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 2.1E-80 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11730 7606856c259b791fa04eaea176094419 359 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 3.3E-5 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11730 7606856c259b791fa04eaea176094419 359 Pfam PF00953 Glycosyl transferase family 4 86 276 8.8E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Pfam PF11798 IMS family HHH motif 170 200 3.2E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Gene3D G3DSA:3.30.1490.100 248 351 1.7E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Pfam PF11799 impB/mucB/samB family C-terminal domain 238 348 5.8E-18 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 SUPERFAMILY SSF100879 243 342 5.81E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Gene3D G3DSA:3.30.70.270 116 173 2.3E-13 T 28-03-2018 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Gene3D G3DSA:3.30.70.270 42 115 1.2E-12 T 28-03-2018 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Pfam PF00817 impB/mucB/samB family 9 156 4.7E-35 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Gene3D G3DSA:1.10.150.20 174 247 3.5E-21 T 28-03-2018 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 Hamap MF_01113 DNA polymerase IV [dinB]. 3 351 33.273 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CP478_RS08425 df44b2f148c55b4aa51fcc6e3e0742de 468 SUPERFAMILY SSF56672 3 241 6.23E-69 T 28-03-2018 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 Gene3D G3DSA:3.40.50.300 219 422 2.3E-37 T 28-03-2018 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 149 422 58.892 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 Gene3D G3DSA:1.20.120.140 114 208 5.4E-13 T 28-03-2018 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 Pfam PF00448 SRP54-type protein, GTPase domain 223 422 7.4E-73 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 150 421 2.9E-105 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 SMART SM00962 223 422 6.3E-101 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 SMART SM00382 222 398 3.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 SUPERFAMILY SSF52540 218 421 3.94E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 SUPERFAMILY SSF47364 121 200 2.22E-15 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 395 408 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 Pfam PF02881 SRP54-type protein, helical bundle domain 138 202 9.9E-6 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS15955 215e498604a42cd3578d5e900c3e8020 422 SMART SM00963 126 206 1.5E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Gene3D G3DSA:1.20.58.280 136 207 2.1E-16 T 28-03-2018 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Pfam PF11896 Domain of unknown function (DUF3416) 16 226 1.9E-56 T 28-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Gene3D G3DSA:3.20.20.80 229 596 2.1E-62 T 28-03-2018 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 SMART SM00642 232 573 0.0012 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 SUPERFAMILY SSF51445 222 593 2.44E-81 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Gene3D G3DSA:2.60.40.10 14 135 1.1E-37 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Pfam PF00128 Alpha amylase, catalytic domain 263 364 1.2E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Gene3D G3DSA:2.60.40.1180 597 696 2.4E-30 T 28-03-2018 CP478_RS07280 5e90895955e0de0c5d8eb79c7dfe60e0 701 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 14 688 45.392 T 28-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 2.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 SMART SM00862 148 223 6.1E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 Gene3D G3DSA:3.40.50.2300 1 112 9.4E-40 T 28-03-2018 CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 Pfam PF00072 Response regulator receiver domain 3 112 3.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 Gene3D G3DSA:1.10.10.10 113 227 1.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 SUPERFAMILY SSF52172 2 182 3.13E-44 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS05360 b0b9bb44e1016708d873150f970e1421 228 SMART SM00448 1 112 6.2E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS11010 3872153a39dac2ebfb78d5f7d0aae60d 346 SMART SM00530 7 62 2.8E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS11010 3872153a39dac2ebfb78d5f7d0aae60d 346 Gene3D G3DSA:1.10.3100.10 1 125 4.2E-17 T 28-03-2018 IPR027910 YdiL-like domain CP478_RS11010 3872153a39dac2ebfb78d5f7d0aae60d 346 SUPERFAMILY SSF47413 3 66 5.63E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS11010 3872153a39dac2ebfb78d5f7d0aae60d 346 Pfam PF01381 Helix-turn-helix 11 61 6.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS11010 3872153a39dac2ebfb78d5f7d0aae60d 346 Pfam PF06114 IrrE N-terminal-like domain 154 264 6.0E-23 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 PIRSF PIRSF001430 22 295 1.8E-69 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 Gene3D G3DSA:3.30.70.580 20 139 3.6E-31 T 28-03-2018 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 Gene3D G3DSA:3.30.70.660 140 277 2.1E-30 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 SUPERFAMILY SSF55120 21 288 2.16E-71 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 22 278 30.644 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 Pfam PF01416 tRNA pseudouridine synthase 178 279 3.4E-23 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18910 966f5d3d35658da2b91274375eac3c55 297 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 24 272 2.3E-45 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS14640 af9e2064746de47e3e37ff70b4d96b7f 369 SUPERFAMILY SSF52540 99 273 1.04E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14640 af9e2064746de47e3e37ff70b4d96b7f 369 Gene3D G3DSA:3.40.50.300 72 271 9.9E-6 T 28-03-2018 CP478_RS14640 af9e2064746de47e3e37ff70b4d96b7f 369 Pfam PF03969 AFG1-like ATPase 33 247 2.6E-72 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CP478_RS11560 04b2f26d7ad1fb73407538170a8b2d6c 292 Gene3D G3DSA:1.10.287.100 221 261 8.6E-12 T 28-03-2018 CP478_RS11560 04b2f26d7ad1fb73407538170a8b2d6c 292 Pfam PF09754 PAC2 family 22 238 1.1E-49 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CP478_RS11560 04b2f26d7ad1fb73407538170a8b2d6c 292 SUPERFAMILY SSF159659 9 262 1.23E-86 T 28-03-2018 CP478_RS11560 04b2f26d7ad1fb73407538170a8b2d6c 292 PIRSF PIRSF028754 1 290 1.6E-127 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CP478_RS10215 8ab3a47ec6ae509b1b56965d0d75760d 450 Gene3D G3DSA:3.30.590.10 108 445 6.3E-86 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CP478_RS10215 8ab3a47ec6ae509b1b56965d0d75760d 450 Gene3D G3DSA:3.10.20.70 13 107 2.7E-11 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS10215 8ab3a47ec6ae509b1b56965d0d75760d 450 SUPERFAMILY SSF55931 111 435 1.13E-78 T 28-03-2018 CP478_RS10215 8ab3a47ec6ae509b1b56965d0d75760d 450 SMART SM01230 111 358 1.1E-69 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS10215 8ab3a47ec6ae509b1b56965d0d75760d 450 Pfam PF00120 Glutamine synthetase, catalytic domain 112 432 8.7E-64 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS18360 006ec281b2f53c1f6ac7152bf0362316 123 Pfam PF01565 FAD binding domain 1 68 1.6E-8 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS18360 006ec281b2f53c1f6ac7152bf0362316 123 Gene3D G3DSA:3.30.465.10 1 122 1.3E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS18360 006ec281b2f53c1f6ac7152bf0362316 123 SUPERFAMILY SSF56176 1 101 2.85E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 Gene3D G3DSA:3.30.540.10 150 315 2.7E-56 T 28-03-2018 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 Gene3D G3DSA:3.30.540.10 1 149 1.7E-49 T 28-03-2018 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 PIRSF PIRSF004532 1 315 2.4E-150 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 309 6.0E-110 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 SUPERFAMILY SSF56655 1 307 3.66E-109 T 28-03-2018 CP478_RS06035 3294c6bfbaed5efbadaf595e8c81e923 328 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 1 304 1.3E-138 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CP478_RS06165 56af62632b70373997a42e08e0a1032f 201 SUPERFAMILY SSF46785 3 52 3.62E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06165 56af62632b70373997a42e08e0a1032f 201 Gene3D G3DSA:1.10.10.10 1 136 3.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01585 afc499a6a0de0ab147bd681252c01e9e 261 Pfam PF13489 Methyltransferase domain 14 135 7.1E-13 T 28-03-2018 CP478_RS01585 afc499a6a0de0ab147bd681252c01e9e 261 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 254 46.048 T 28-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS01585 afc499a6a0de0ab147bd681252c01e9e 261 Gene3D G3DSA:3.40.50.150 1 177 1.1E-28 T 28-03-2018 CP478_RS01585 afc499a6a0de0ab147bd681252c01e9e 261 SUPERFAMILY SSF53335 15 246 3.91E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01585 afc499a6a0de0ab147bd681252c01e9e 261 Gene3D G3DSA:1.10.150.290 178 233 5.1E-24 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.2E-59 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 Gene3D G3DSA:3.40.50.10860 8 144 5.8E-42 T 28-03-2018 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 120 5.5E-34 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 Gene3D G3DSA:3.40.50.720 145 263 3.5E-31 T 28-03-2018 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 SUPERFAMILY SSF53223 3 121 1.44E-34 T 28-03-2018 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 4.4E-60 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 SUPERFAMILY SSF51735 122 279 4.6E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18385 814cbc1899f35c872169524af30fc2e0 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 34.811 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 Gene3D G3DSA:1.10.10.10 272 379 1.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 SMART SM00862 301 372 1.3E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 Gene3D G3DSA:3.40.50.10090 43 175 3.3E-19 T 28-03-2018 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 SUPERFAMILY SSF46894 286 372 1.19E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 268 2.3E-38 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 Gene3D G3DSA:3.40.50.10090 176 271 5.7E-12 T 28-03-2018 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 Pfam PF00486 Transcriptional regulatory protein, C terminal 306 372 5.5E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS01405 3cfbb5e96ebb6299985ee189d9dcf2e2 381 SUPERFAMILY SSF69618 11 276 7.85E-54 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS15315 f9e0499e482152dcf0ce07e340c3f4a3 108 Gene3D G3DSA:1.10.287.1060 1 95 3.8E-8 T 28-03-2018 CP478_RS15315 f9e0499e482152dcf0ce07e340c3f4a3 108 SUPERFAMILY SSF140453 2 93 1.27E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 Gene3D G3DSA:3.40.50.1480 3 268 4.3E-109 T 28-03-2018 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 275 291 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 92 106 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SUPERFAMILY SSF52283 19 167 1.64E-111 T 28-03-2018 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SUPERFAMILY SSF52283 416 495 1.64E-111 T 28-03-2018 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SUPERFAMILY SSF52283 205 252 1.64E-111 T 28-03-2018 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 Gene3D G3DSA:3.40.50.1480 269 468 1.7E-77 T 28-03-2018 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 PIRSF PIRSF001109 7 495 3.8E-196 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 21 487 4.3E-208 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 253 415 1.8E-78 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SMART SM00996 20 494 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 16 487 47.899 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SUPERFAMILY SSF51735 253 415 1.46E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 SMART SM00997 253 415 2.9E-101 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS17810 2225ef8fa9cc978fde8a933b8631076d 495 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 20 494 1.7E-146 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CP478_RS00940 676091c5fc3c480987c88c312608984d 515 Pfam PF02470 MlaD protein 40 112 2.9E-11 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS00940 676091c5fc3c480987c88c312608984d 515 Gene3D G3DSA:1.20.1420.10 116 275 6.8E-4 T 28-03-2018 CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 2.8E-100 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00940 676091c5fc3c480987c88c312608984d 515 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 292 1.9E-84 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS09185 5e59e5a61af4547cbdaa021df5763bd9 305 Gene3D G3DSA:1.20.5.170 78 135 0.048 T 28-03-2018 CP478_RS09185 5e59e5a61af4547cbdaa021df5763bd9 305 Gene3D G3DSA:1.20.5.490 62 77 5.3E-4 T 28-03-2018 CP478_RS09185 5e59e5a61af4547cbdaa021df5763bd9 305 Pfam PF05103 DivIVA protein 34 148 2.9E-6 T 28-03-2018 IPR007793 DivIVA family CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 Gene3D G3DSA:1.10.630.10 78 486 3.3E-64 T 28-03-2018 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 172 183 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 405 420 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 218 234 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 235 250 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 360 371 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 426 435 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 435 446 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 PRINTS PR00359 B-class P450 signature 377 404 2.4E-31 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 SUPERFAMILY SSF48264 102 486 2.49E-78 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 428 437 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS12335 91db16e793636d3934f52ecb7c923999 489 Pfam PF00067 Cytochrome P450 358 455 6.4E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 SUPERFAMILY SSF51011 628 730 3.45E-34 T 28-03-2018 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 SUPERFAMILY SSF51445 191 621 6.1E-112 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 130 216 8.1E-23 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Gene3D G3DSA:2.60.40.10 117 232 5.5E-29 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 106 731 43.282 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Gene3D G3DSA:3.20.20.80 248 639 1.4E-79 T 28-03-2018 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 PIRSF PIRSF000463 15 731 6.9E-278 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Gene3D G3DSA:2.60.40.10 12 113 1.6E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 114 728 2.9E-266 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 SUPERFAMILY SSF81296 23 119 7.56E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 SUPERFAMILY SSF81296 148 209 2.59E-11 T 28-03-2018 IPR014756 Immunoglobulin E-set CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Pfam PF00128 Alpha amylase, catalytic domain 280 349 3.9E-10 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 SMART SM00642 259 611 1.1E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 633 730 1.2E-21 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CP478_RS07275 9ca38d46c0d564237f6de12fea441790 731 Gene3D G3DSA:2.60.40.1180 640 731 2.8E-35 T 28-03-2018 CP478_RS16600 e12135cf768666692ab8be2699f3d2fe 300 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 219 253 1.9E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS16600 e12135cf768666692ab8be2699f3d2fe 300 Gene3D G3DSA:2.160.10.10 23 299 2.2E-31 T 28-03-2018 CP478_RS16600 e12135cf768666692ab8be2699f3d2fe 300 SUPERFAMILY SSF51161 90 276 2.75E-33 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS09555 326ae192a7ab52b43d92aa07275aca41 149 SUPERFAMILY SSF55347 1 88 3.11E-15 T 28-03-2018 CP478_RS09555 326ae192a7ab52b43d92aa07275aca41 149 Gene3D G3DSA:3.30.360.10 1 139 2.7E-12 T 28-03-2018 CP478_RS13835 16c78a2bab5950588071997e86dd3930 240 SUPERFAMILY SSF51445 56 204 6.95E-8 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS13835 16c78a2bab5950588071997e86dd3930 240 Pfam PF08924 Domain of unknown function (DUF1906) 51 176 4.1E-29 T 28-03-2018 IPR015020 Protein of unknown function DUF1906 CP478_RS13835 16c78a2bab5950588071997e86dd3930 240 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 28 7.1E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CP478_RS13835 16c78a2bab5950588071997e86dd3930 240 Gene3D G3DSA:3.20.20.80 42 232 3.9E-19 T 28-03-2018 CP478_RS06395 1d15847152f7d6acc5e976f5d5fda8c8 246 Gene3D G3DSA:1.20.950.20 5 220 2.1E-43 T 28-03-2018 CP478_RS06395 1d15847152f7d6acc5e976f5d5fda8c8 246 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 8 228 1.9E-57 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CP478_RS06395 1d15847152f7d6acc5e976f5d5fda8c8 246 Pfam PF02665 Nitrate reductase gamma subunit 9 228 6.8E-84 T 28-03-2018 IPR023234 NarG-like domain CP478_RS06395 1d15847152f7d6acc5e976f5d5fda8c8 246 SUPERFAMILY SSF103501 9 228 7.85E-63 T 28-03-2018 IPR023234 NarG-like domain CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 332 7.1E-76 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 SUPERFAMILY SSF51905 555 652 7.56E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 SUPERFAMILY SSF51905 462 520 7.56E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 Gene3D G3DSA:3.40.50.720 372 479 2.6E-25 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 378 636 8.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 SUPERFAMILY SSF51971 335 517 3.85E-41 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 400 3.6E-7 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 621 635 3.6E-7 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 514 523 3.6E-7 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 Gene3D G3DSA:3.20.20.70 4 371 1.5E-105 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 SUPERFAMILY SSF51395 1 368 2.53E-105 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 620 636 1.4E-9 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 379 398 1.4E-9 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 499 517 1.4E-9 T 28-03-2018 CP478_RS06450 3f6aa45c92a2927fa80dc61eec4d555c 674 Gene3D G3DSA:3.50.50.60 480 627 1.1E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02245 7878661138114b56a719bd4a92749567 209 SUPERFAMILY SSF53474 5 188 1.77E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02245 7878661138114b56a719bd4a92749567 209 Gene3D G3DSA:3.40.50.1820 2 203 1.3E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 SUPERFAMILY SSF140459 3 169 8.37E-57 T 28-03-2018 CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF00823 PPE family 5 162 1.3E-55 T 28-03-2018 IPR000030 PPE family CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 339 376 4.0E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 378 416 5.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 260 299 1.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 190 229 4.8E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 448 483 1.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 250 288 5.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Pfam PF01469 Pentapeptide repeats (8 copies) 210 249 1.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS17295 d97d234cdbf146ce63d6c9bde6d0f942 590 Gene3D G3DSA:1.10.287.1060 23 111 1.2E-4 T 28-03-2018 CP478_RS05595 dc9516c46e532d313c992bd8c1dab3a8 243 SUPERFAMILY SSF53955 49 242 1.2E-33 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS05595 dc9516c46e532d313c992bd8c1dab3a8 243 Gene3D G3DSA:1.10.530.10 76 242 1.6E-24 T 28-03-2018 CP478_RS05595 dc9516c46e532d313c992bd8c1dab3a8 243 Pfam PF13406 Transglycosylase SLT domain 156 201 1.5E-5 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 SUPERFAMILY SSF48498 89 200 2.93E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 Gene3D G3DSA:1.10.357.10 84 201 3.4E-21 T 28-03-2018 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 Gene3D G3DSA:1.10.260.40 55 83 1.3E-8 T 28-03-2018 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 SUPERFAMILY SSF46689 10 77 3.39E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS09200 c1e926ed1310f8dc1a3fb5adf8ac69ef 207 Gene3D G3DSA:1.10.10.60 5 54 4.3E-21 T 28-03-2018 CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 8 422 3.3E-129 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 SUPERFAMILY SSF56436 168 424 2.45E-70 T 28-03-2018 IPR016187 C-type lectin fold CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 Gene3D G3DSA:1.20.120.450 1 143 2.9E-14 T 28-03-2018 CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 425 47.64 T 28-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 SUPERFAMILY SSF109854 5 133 4.21E-15 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 Pfam PF03781 Sulfatase-modifying factor enzyme 1 166 422 2.1E-63 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 Pfam PF12867 DinB superfamily 11 137 2.7E-17 T 28-03-2018 IPR024775 DinB-like domain CP478_RS20230 07627d1930d55dd7e853d08b2a061675 425 Gene3D G3DSA:3.90.1580.10 153 425 1.1E-63 T 28-03-2018 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 SUPERFAMILY SSF56176 54 278 1.26E-43 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 Gene3D G3DSA:3.30.43.10 38 156 4.7E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 SUPERFAMILY SSF55103 280 528 1.26E-38 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 Gene3D G3DSA:3.30.465.10 160 297 2.6E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 Gene3D G3DSA:1.10.45.10 489 527 3.5E-14 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 Pfam PF01565 FAD binding domain 106 237 1.1E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS12245 a3d518d1da4760731ce8bdad664ebfec 529 Pfam PF02913 FAD linked oxidases, C-terminal domain 277 527 4.2E-45 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CP478_RS20810 85265cd0b05c9e06243c22a637fb2a17 539 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 221 373 6.5E-15 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS20810 85265cd0b05c9e06243c22a637fb2a17 539 Pfam PF08310 LGFP repeat 420 471 7.5E-16 T 28-03-2018 IPR013207 LGFP CP478_RS20810 85265cd0b05c9e06243c22a637fb2a17 539 SMART SM00701 196 344 3.3E-70 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS20810 85265cd0b05c9e06243c22a637fb2a17 539 SUPERFAMILY SSF55846 196 388 1.02E-48 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS20810 85265cd0b05c9e06243c22a637fb2a17 539 Gene3D G3DSA:3.40.80.10 187 395 1.7E-45 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS00495 fc4a712496be954e44d16dc4ac46a060 197 SUPERFAMILY SSF53335 10 158 1.06E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS00495 fc4a712496be954e44d16dc4ac46a060 197 Pfam PF08241 Methyltransferase domain 27 120 6.8E-20 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS00495 fc4a712496be954e44d16dc4ac46a060 197 Gene3D G3DSA:3.40.50.150 3 176 1.9E-31 T 28-03-2018 CP478_RS17425 0c8818cf125da0fbf33037846dbf70db 109 SUPERFAMILY SSF47413 30 105 5.07E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS17425 0c8818cf125da0fbf33037846dbf70db 109 Pfam PF13744 Helix-turn-helix domain 35 98 1.8E-10 T 28-03-2018 CP478_RS17425 0c8818cf125da0fbf33037846dbf70db 109 SMART SM00530 40 97 2.6E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS17425 0c8818cf125da0fbf33037846dbf70db 109 Gene3D G3DSA:3.30.1190.10 64 109 3.3E-11 T 28-03-2018 CP478_RS17425 0c8818cf125da0fbf33037846dbf70db 109 Gene3D G3DSA:1.10.10.60 36 63 5.9E-9 T 28-03-2018 CP478_RS08035 63756ec84e88feedb01d49d9afc0a367 115 Gene3D G3DSA:3.30.300.130 8 110 1.5E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CP478_RS08035 63756ec84e88feedb01d49d9afc0a367 115 Pfam PF01883 Iron-sulfur cluster assembly protein 13 87 5.8E-19 T 28-03-2018 IPR002744 MIP18 family-like CP478_RS08035 63756ec84e88feedb01d49d9afc0a367 115 SUPERFAMILY SSF117916 13 109 1.05E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 Gene3D G3DSA:3.40.50.1100 155 343 5.0E-47 T 28-03-2018 CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 TIGRFAM TIGR00260 thrC: threonine synthase 17 334 2.6E-93 T 28-03-2018 IPR004450 Threonine synthase-like CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 327 4.3E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 Gene3D G3DSA:3.40.50.1100 47 154 9.9E-28 T 28-03-2018 CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 60 73 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 PIRSF PIRSF038945 1 359 3.2E-178 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CP478_RS07085 1f5553e738c9acb9792914ba08067e1e 360 SUPERFAMILY SSF53686 12 341 1.83E-102 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS11030 dc0230ae0fb2f4dec311ad1b6f110f2a 101 SUPERFAMILY SSF47413 33 97 1.3E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS11030 dc0230ae0fb2f4dec311ad1b6f110f2a 101 SMART SM00530 34 90 2.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS11030 dc0230ae0fb2f4dec311ad1b6f110f2a 101 Gene3D G3DSA:1.10.260.40 13 93 4.8E-13 T 28-03-2018 CP478_RS11030 dc0230ae0fb2f4dec311ad1b6f110f2a 101 Pfam PF13744 Helix-turn-helix domain 32 92 3.9E-13 T 28-03-2018 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 Pfam PF01795 MraW methylase family 63 379 8.8E-119 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 Gene3D G3DSA:3.40.50.150 61 151 3.1E-5 T 28-03-2018 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 65 380 36.424 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 SUPERFAMILY SSF81799 184 285 1.09E-33 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 SUPERFAMILY SSF53335 65 183 2.61E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 SUPERFAMILY SSF53335 285 380 2.61E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 89 379 1.3E-85 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS11775 87d3b0eddfa655abacc1fecf410c1e22 396 Gene3D G3DSA:1.10.150.170 182 287 2.0E-37 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS15695 d98ba70d531d7d143a1da9609363ff92 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 38 2.0E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS15695 d98ba70d531d7d143a1da9609363ff92 85 Gene3D G3DSA:1.10.1220.10 1 39 4.2E-11 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS15695 d98ba70d531d7d143a1da9609363ff92 85 SUPERFAMILY SSF47598 2 43 1.72E-7 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS03425 973b820aa10fb34c75fb9f947ed89656 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03425 973b820aa10fb34c75fb9f947ed89656 55 SUPERFAMILY SSF57829 5 55 7.94E-20 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CP478_RS03425 973b820aa10fb34c75fb9f947ed89656 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 6 55 2.4E-21 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03425 973b820aa10fb34c75fb9f947ed89656 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 19.619 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03425 973b820aa10fb34c75fb9f947ed89656 55 Pfam PF00471 Ribosomal protein L33 10 55 2.3E-23 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08885 8da6820360895942acab1414e86f67b8 443 ProSitePatterns PS00452 Guanylate cyclase signature. 355 378 - T 28-03-2018 IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site GO:0009190|GO:0016849|GO:0035556 CP478_RS08885 8da6820360895942acab1414e86f67b8 443 Gene3D G3DSA:3.30.70.1230 227 424 7.9E-65 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS08885 8da6820360895942acab1414e86f67b8 443 SMART SM00044 214 412 9.5E-87 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS08885 8da6820360895942acab1414e86f67b8 443 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 244 422 2.2E-58 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS08885 8da6820360895942acab1414e86f67b8 443 SUPERFAMILY SSF55073 240 422 1.57E-62 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS10920 f50837d364f7db25e6bc84e021b8aad7 285 Pfam PF08241 Methyltransferase domain 102 187 4.3E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS10920 f50837d364f7db25e6bc84e021b8aad7 285 SUPERFAMILY SSF53335 66 242 2.95E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10920 f50837d364f7db25e6bc84e021b8aad7 285 Gene3D G3DSA:3.40.50.150 70 243 1.7E-20 T 28-03-2018 CP478_RS08715 59288036e8176eced68dd2c90fd1dc0b 446 PIRSF PIRSF029171 25 407 3.5E-31 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CP478_RS08715 59288036e8176eced68dd2c90fd1dc0b 446 Gene3D G3DSA:3.40.50.1820 65 402 9.2E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS08715 59288036e8176eced68dd2c90fd1dc0b 446 Pfam PF03583 Secretory lipase 129 406 5.0E-101 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CP478_RS08715 59288036e8176eced68dd2c90fd1dc0b 446 SUPERFAMILY SSF53474 92 239 2.1E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS08715 59288036e8176eced68dd2c90fd1dc0b 446 SUPERFAMILY SSF53474 294 398 2.1E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04770 244698bd584276048de26203773d0932 386 SMART SM01204 221 365 3.4E-30 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS04770 244698bd584276048de26203773d0932 386 PIRSF PIRSF018953 1 386 3.1E-149 T 28-03-2018 IPR016741 Uncharacterised conserved protein UCP018953 CP478_RS04770 244698bd584276048de26203773d0932 386 Pfam PF10442 FIST C domain 222 364 1.1E-24 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS04770 244698bd584276048de26203773d0932 386 SMART SM00897 33 220 1.8E-20 T 28-03-2018 IPR013702 FIST domain, N-terminal CP478_RS04770 244698bd584276048de26203773d0932 386 Pfam PF08495 FIST N domain 35 219 5.6E-22 T 28-03-2018 IPR013702 FIST domain, N-terminal CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Gene3D G3DSA:1.10.60.10 75 129 2.6E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 SMART SM00899 152 229 1.3E-11 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.3E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 SUPERFAMILY SSF47979 65 134 4.05E-27 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Gene3D G3DSA:2.30.30.90 130 229 1.1E-17 T 28-03-2018 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Gene3D G3DSA:1.10.10.10 1 73 5.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 SUPERFAMILY SSF46785 2 62 8.28E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Pfam PF04023 FeoA domain 152 228 2.1E-9 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 3.4E-21 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 SUPERFAMILY SSF50037 130 230 1.12E-23 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CP478_RS14860 c32541dbbb3edb7ae8661e485f2b60b2 230 SMART SM00529 26 125 3.5E-47 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CP478_RS12960 0d3f5585f1699204a1304c69530e560a 71 SMART SM00923 4 54 4.7E-34 T 28-03-2018 IPR005153 MbtH-like protein CP478_RS12960 0d3f5585f1699204a1304c69530e560a 71 Gene3D G3DSA:3.90.820.10 3 69 1.9E-37 T 28-03-2018 CP478_RS12960 0d3f5585f1699204a1304c69530e560a 71 SUPERFAMILY SSF160582 3 70 7.72E-33 T 28-03-2018 CP478_RS12960 0d3f5585f1699204a1304c69530e560a 71 Pfam PF03621 MbtH-like protein 2 53 5.6E-30 T 28-03-2018 IPR005153 MbtH-like protein CP478_RS15495 03d5ad41feee925b21dc82c82eaf45a1 436 Gene3D G3DSA:3.40.190.10 171 362 1.2E-28 T 28-03-2018 CP478_RS15495 03d5ad41feee925b21dc82c82eaf45a1 436 Pfam PF13416 Bacterial extracellular solute-binding protein 67 356 1.5E-41 T 28-03-2018 CP478_RS15495 03d5ad41feee925b21dc82c82eaf45a1 436 Gene3D G3DSA:3.40.190.10 39 170 1.1E-17 T 28-03-2018 CP478_RS15495 03d5ad41feee925b21dc82c82eaf45a1 436 SUPERFAMILY SSF53850 39 420 1.25E-64 T 28-03-2018 CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 235 312 1.4E-13 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 SUPERFAMILY SSF81464 39 142 1.36E-20 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 SUPERFAMILY SSF49503 147 170 1.0E-35 T 28-03-2018 IPR008972 Cupredoxin CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 SUPERFAMILY SSF49503 229 352 1.0E-35 T 28-03-2018 IPR008972 Cupredoxin CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 Gene3D G3DSA:1.10.287.90 54 142 2.2E-18 T 28-03-2018 CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 252 306 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS11960 238c1cc1d4d1342f191fc0955644ad37 363 Gene3D G3DSA:2.60.40.420 148 326 1.5E-43 T 28-03-2018 IPR008972 Cupredoxin CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 4.0E-52 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 SUPERFAMILY SSF54913 212 283 9.89E-21 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 283 9.3E-28 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Gene3D G3DSA:3.40.190.10 1 111 2.3E-36 T 28-03-2018 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 284 32.075 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Pfam PF01634 ATP phosphoribosyltransferase 49 204 2.9E-39 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 SUPERFAMILY SSF53850 1 208 1.02E-62 T 28-03-2018 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Gene3D G3DSA:3.30.70.120 212 276 3.2E-25 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Pfam PF08029 HisG, C-terminal domain 210 279 5.0E-24 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 Gene3D G3DSA:3.40.190.10 112 209 6.9E-21 T 28-03-2018 CP478_RS11540 f8dad4126181f884ae0f413a6d240bbd 284 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 Gene3D G3DSA:2.40.110.10 115 209 1.1E-16 T 28-03-2018 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 Gene3D G3DSA:1.20.140.10 222 394 5.4E-16 T 28-03-2018 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 SUPERFAMILY SSF56645 11 208 1.7E-34 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 SUPERFAMILY SSF47203 230 384 1.58E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 372 2.7E-41 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 PIRSF PIRSF016578 1 394 8.3E-142 T 28-03-2018 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 Gene3D G3DSA:1.10.540.10 2 112 4.0E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19515 1e69afbac5a977b7d46a6ced9caf7620 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 88 2.2E-4 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 2.9E-6 T 28-03-2018 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.9E-6 T 28-03-2018 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 SUPERFAMILY SSF51905 303 414 6.37E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 SUPERFAMILY SSF51905 11 234 6.37E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 Pfam PF00743 Flavin-binding monooxygenase-like 12 225 4.9E-16 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 Gene3D G3DSA:3.50.50.60 172 433 2.7E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03020 0dceb506458a05dda23bf7af87e884fb 486 Gene3D G3DSA:3.50.50.60 10 171 1.7E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16230 6cca1f651f0e3cb8c55cbab9849577df 255 Pfam PF13462 Thioredoxin 73 235 2.5E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS16230 6cca1f651f0e3cb8c55cbab9849577df 255 SUPERFAMILY SSF52833 72 232 1.43E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS16230 6cca1f651f0e3cb8c55cbab9849577df 255 Gene3D G3DSA:3.40.30.10 69 245 1.9E-29 T 28-03-2018 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Gene3D G3DSA:3.30.1490.20 21 87 1.0E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Gene3D G3DSA:3.40.50.261 232 385 5.9E-37 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Pfam PF00549 CoA-ligase 256 378 4.9E-12 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 SUPERFAMILY SSF56059 1 226 2.3E-63 T 28-03-2018 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 SUPERFAMILY SSF52210 231 385 3.92E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Pfam PF08442 ATP-grasp domain 2 194 1.6E-69 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 37.089 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 5.5E-122 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 PIRSF PIRSF001554 1 387 3.7E-134 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05190 2e550913744944f15aeee897cf2ca4d6 387 Gene3D G3DSA:3.30.470.20 88 231 8.8E-48 T 28-03-2018 CP478_RS07300 c3e483c097e32113836339d16f29ea86 101 SUPERFAMILY SSF54736 25 98 2.41E-23 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CP478_RS07300 c3e483c097e32113836339d16f29ea86 101 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 25 95 8.1E-21 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CP478_RS07300 c3e483c097e32113836339d16f29ea86 101 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 19 101 17.185 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CP478_RS07300 c3e483c097e32113836339d16f29ea86 101 Gene3D G3DSA:3.30.1390.10 26 97 1.3E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CP478_RS15885 daff7021f820a8cfb21c3c09a035cd2a 80 Hamap MF_00088 UPF0109 protein . 5 76 20.924 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CP478_RS15885 daff7021f820a8cfb21c3c09a035cd2a 80 SUPERFAMILY SSF54814 19 63 5.3E-8 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CP478_RS15885 daff7021f820a8cfb21c3c09a035cd2a 80 Pfam PF13083 KH domain 7 67 4.7E-20 T 28-03-2018 CP478_RS15885 daff7021f820a8cfb21c3c09a035cd2a 80 Gene3D G3DSA:3.30.300.20 2 77 2.0E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS21320 867bbe556cd26b68a3f049d94080a193 176 Pfam PF15598 Immunity protein 61 14 167 5.4E-57 T 28-03-2018 IPR028953 Immunity protein IFT-like CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 SUPERFAMILY SSF51735 4 192 4.47E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 SUPERFAMILY SSF52413 312 434 9.68E-34 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 419 2.1E-131 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 SUPERFAMILY SSF48179 204 302 4.87E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Gene3D G3DSA:1.20.5.100 205 227 3.0E-13 T 28-03-2018 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 298 3.3E-31 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 PIRSF PIRSF500134 1 441 1.2E-151 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Gene3D G3DSA:3.40.50.720 2 201 2.0E-51 T 28-03-2018 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Gene3D G3DSA:3.40.50.720 228 435 5.9E-66 T 28-03-2018 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 422 6.6E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 181 2.1E-60 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 SMART SM00984 322 423 5.5E-43 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CP478_RS01725 a5835cdcf154f856d69d83b4c6449584 443 PIRSF PIRSF000124 1 438 4.4E-117 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CP478_RS03805 12252257de8d196a42851deec256219f 217 Pfam PF00297 Ribosomal protein L3 92 187 8.4E-18 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03805 12252257de8d196a42851deec256219f 217 SUPERFAMILY SSF50447 3 215 3.18E-82 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS03805 12252257de8d196a42851deec256219f 217 Gene3D G3DSA:4.10.960.10 59 170 7.4E-35 T 28-03-2018 CP478_RS03805 12252257de8d196a42851deec256219f 217 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 3 212 39.591 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03805 12252257de8d196a42851deec256219f 217 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 209 2.5E-87 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03805 12252257de8d196a42851deec256219f 217 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 Gene3D G3DSA:3.40.1360.10 76 174 1.4E-37 T 28-03-2018 CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 SMART SM00493 79 168 1.9E-16 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 Pfam PF02132 RecR protein 39 77 4.6E-13 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 Pfam PF13662 Toprim domain 79 175 6.9E-22 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 9.8E-84 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 Gene3D G3DSA:1.10.150.20 10 45 0.0072 T 28-03-2018 CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 SMART SM00278 11 30 0.0059 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 SUPERFAMILY SSF111304 2 202 3.01E-68 T 28-03-2018 IPR023627 Recombination protein RecR CP478_RS20295 271fb0ed3471656bb1e54c2c76e7080d 203 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 99.577 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CP478_RS05185 3b099e16636925dfd3b330c6257caef0 332 Pfam PF01551 Peptidase family M23 222 316 6.6E-30 T 28-03-2018 IPR016047 Peptidase M23 CP478_RS05185 3b099e16636925dfd3b330c6257caef0 332 SUPERFAMILY SSF51261 197 320 5.36E-48 T 28-03-2018 IPR011055 Duplicated hybrid motif CP478_RS05185 3b099e16636925dfd3b330c6257caef0 332 Gene3D G3DSA:2.70.70.10 108 323 2.1E-43 T 28-03-2018 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 215 241 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 267 291 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 311 327 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 60 76 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 242 266 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 292 310 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 PRINTS PR01050 Pyruvate kinase family signature 185 199 5.5E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Pfam PF00224 Pyruvate kinase, barrel domain 3 335 5.4E-118 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 SUPERFAMILY SSF51621 2 76 2.65E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 SUPERFAMILY SSF51621 166 336 2.65E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Pfam PF02887 Pyruvate kinase, alpha/beta domain 354 465 2.4E-22 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 SUPERFAMILY SSF52935 322 468 2.62E-33 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Gene3D G3DSA:3.40.1380.20 320 468 1.3E-39 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 3.3E-172 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 SUPERFAMILY SSF50800 71 164 1.17E-22 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Gene3D G3DSA:2.40.33.10 82 158 4.1E-25 T 28-03-2018 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Gene3D G3DSA:3.20.20.60 159 319 3.3E-63 T 28-03-2018 CP478_RS08845 92e9237c01435eccc0a193a3b97c2cd0 472 Gene3D G3DSA:3.20.20.60 1 81 2.8E-15 T 28-03-2018 CP478_RS05430 716b49206a634d20790577bbf2265e30 203 Pfam PF13302 Acetyltransferase (GNAT) domain 14 158 6.6E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS05430 716b49206a634d20790577bbf2265e30 203 SUPERFAMILY SSF55729 13 181 3.47E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS05430 716b49206a634d20790577bbf2265e30 203 Gene3D G3DSA:3.40.630.30 4 189 3.4E-25 T 28-03-2018 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Pfam PF00925 GTP cyclohydrolase II 210 381 5.2E-73 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 SUPERFAMILY SSF142695 207 384 2.22E-69 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 200 3.3E-84 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 206 37.631 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 210 404 2.6E-74 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 403 57.839 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 407 40.334 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 PIRSF PIRSF001259 2 413 1.6E-175 T 28-03-2018 CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 Gene3D G3DSA:3.90.870.10 1 215 1.3E-94 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 SUPERFAMILY SSF55821 5 208 7.78E-82 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS07745 70146f5ff4c7c97e00c41d7c352c36f7 425 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 202 1.2E-71 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS03475 c9a24fff6aa1adc7813f82a0dd148aba 293 SUPERFAMILY SSF53335 19 293 7.83E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03475 c9a24fff6aa1adc7813f82a0dd148aba 293 Gene3D G3DSA:3.40.50.150 7 293 3.3E-56 T 28-03-2018 CP478_RS03475 c9a24fff6aa1adc7813f82a0dd148aba 293 Pfam PF02353 Mycolic acid cyclopropane synthetase 10 289 1.2E-125 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03475 c9a24fff6aa1adc7813f82a0dd148aba 293 PIRSF PIRSF003085 2 293 1.2E-107 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS16405 d8aebee8f65cf42bc1437e3b81c64545 94 SUPERFAMILY SSF158472 25 73 9.94E-6 T 28-03-2018 CP478_RS16405 d8aebee8f65cf42bc1437e3b81c64545 94 SMART SM00304 22 75 1.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS16405 d8aebee8f65cf42bc1437e3b81c64545 94 Gene3D G3DSA:1.10.287.130 66 94 9.2E-6 T 28-03-2018 CP478_RS16405 d8aebee8f65cf42bc1437e3b81c64545 94 SUPERFAMILY SSF47384 59 93 4.12E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Gene3D G3DSA:3.30.420.40 172 334 1.8E-47 T 28-03-2018 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 SUPERFAMILY SSF53067 4 160 3.33E-57 T 28-03-2018 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 620 36.163 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Pfam PF00012 Hsp70 protein 80 583 1.5E-219 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Pfam PF00012 Hsp70 protein 4 78 2.6E-28 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Gene3D G3DSA:3.30.420.40 1 171 8.2E-67 T 28-03-2018 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 582 3.3E-274 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 SUPERFAMILY SSF53067 162 356 2.06E-63 T 28-03-2018 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Gene3D G3DSA:2.60.34.10 364 505 1.2E-70 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 Gene3D G3DSA:1.20.1270.10 506 596 1.1E-21 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 31 43 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 54 62 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 114 134 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 443 459 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 362 381 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 307 323 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 339 359 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 PRINTS PR00301 70kDa heat shock protein signature 174 184 4.2E-76 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 SUPERFAMILY SSF100920 358 514 1.16E-63 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CP478_RS01870 bf5ca57f8bf45a7bc23a450242a58b32 625 SUPERFAMILY SSF100934 481 583 5.23E-14 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CP478_RS20575 e18237aabd90b2118781bf4a59c47e44 119 Gene3D G3DSA:3.10.450.50 3 114 9.6E-15 T 28-03-2018 CP478_RS20575 e18237aabd90b2118781bf4a59c47e44 119 SUPERFAMILY SSF54427 8 114 2.06E-18 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS20575 e18237aabd90b2118781bf4a59c47e44 119 Pfam PF12680 SnoaL-like domain 18 109 5.9E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS20085 7b410c424758bf6757d2b27b59f5f42b 53 Pfam PF13783 Domain of unknown function (DUF4177) 7 42 5.3E-6 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 Pfam PF00834 Ribulose-phosphate 3 epimerase family 13 207 2.6E-83 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 38 52 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 PIRSF PIRSF001461 7 232 4.5E-96 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 12 220 1.9E-86 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 SUPERFAMILY SSF51366 12 222 1.41E-67 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 140 162 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CP478_RS07710 b4dbe3d1d8abbda4a768e44c867880f2 232 Gene3D G3DSA:3.20.20.70 3 223 5.1E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 10 934 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 SUPERFAMILY SSF53383 10 438 6.14E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Gene3D G3DSA:3.90.1150.10 343 443 8.7E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Gene3D G3DSA:3.40.640.10 97 342 2.2E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Gene3D G3DSA:3.40.640.10 508 755 1.9E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Pfam PF02347 Glycine cleavage system P-protein 9 438 2.6E-185 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Pfam PF02347 Glycine cleavage system P-protein 461 720 2.7E-11 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 SUPERFAMILY SSF53383 913 936 1.63E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 SUPERFAMILY SSF53383 467 870 1.63E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Gene3D G3DSA:3.90.1150.10 756 888 3.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS09965 7aac94a3b83463d30923dff3994f9717 941 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 940 24.759 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CP478_RS15675 5b58647b252465b3c9282b3baa03d166 284 Gene3D G3DSA:3.40.630.30 142 281 3.2E-15 T 28-03-2018 CP478_RS15675 5b58647b252465b3c9282b3baa03d166 284 Pfam PF13312 Domain of unknown function (DUF4081) 54 156 1.0E-39 T 28-03-2018 IPR025289 Domain of unknown function DUF4081 CP478_RS15675 5b58647b252465b3c9282b3baa03d166 284 SUPERFAMILY SSF55729 145 278 6.2E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS15675 5b58647b252465b3c9282b3baa03d166 284 PIRSF PIRSF021603 1 283 1.7E-145 T 28-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like CP478_RS15675 5b58647b252465b3c9282b3baa03d166 284 Pfam PF08445 FR47-like protein 214 275 1.5E-8 T 28-03-2018 IPR013653 FR47-like GO:0016747 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 SUPERFAMILY SSF53254 155 302 9.64E-21 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 PRINTS PR00502 NUDIX hydrolase family signature 49 63 6.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 PRINTS PR00502 NUDIX hydrolase family signature 63 78 6.3E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 SUPERFAMILY SSF55811 13 149 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 SMART SM00855 155 269 1.6E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 Gene3D G3DSA:3.90.79.10 10 160 1.3E-31 T 28-03-2018 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 Pfam PF00293 NUDIX domain 35 146 5.5E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 157 236 3.8E-12 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS16320 5f24f659f8ac9928d03521c47971922a 317 Gene3D G3DSA:3.40.50.1240 161 307 3.4E-17 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 311 469 1.3E-69 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 SUPERFAMILY SSF47413 4 69 9.01E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 Pfam PF01381 Helix-turn-helix 10 63 1.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 PIRSF PIRSF019251 1 474 3.3E-197 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 SMART SM00530 9 64 8.4E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 Pfam PF06114 IrrE N-terminal-like domain 188 310 8.7E-28 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CP478_RS02480 6f1ce6c73fa68d6ad50250912d74aec8 474 Gene3D G3DSA:1.10.260.40 1 73 2.4E-15 T 28-03-2018 CP478_RS12685 bb8bef3909966b7414f329a2c3ae6c0b 163 Pfam PF01047 MarR family 44 101 4.3E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS12685 bb8bef3909966b7414f329a2c3ae6c0b 163 Gene3D G3DSA:1.10.10.10 30 114 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12685 bb8bef3909966b7414f329a2c3ae6c0b 163 SMART SM00347 38 136 9.9E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS12685 bb8bef3909966b7414f329a2c3ae6c0b 163 Gene3D G3DSA:1.10.287.100 115 151 6.9E-7 T 28-03-2018 CP478_RS12685 bb8bef3909966b7414f329a2c3ae6c0b 163 SUPERFAMILY SSF46785 29 151 3.46E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 71 3.5E-15 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 74 153 1.7E-37 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 75 154 1.4E-35 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 Gene3D G3DSA:1.10.10.10 69 156 5.0E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 124 130 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 SUPERFAMILY SSF53155 2 79 4.51E-21 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 Gene3D G3DSA:3.30.160.70 1 68 8.8E-22 T 28-03-2018 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 154 45.596 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CP478_RS07220 3ec616c0e9ad6f12dbe339eb8062e145 165 SUPERFAMILY SSF46767 73 154 1.11E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 Pfam PF00561 alpha/beta hydrolase fold 55 309 1.6E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 Gene3D G3DSA:3.40.50.1820 5 327 1.3E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 SUPERFAMILY SSF53474 14 322 4.5E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 PRINTS PR00412 Epoxide hydrolase signature 123 136 8.7E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 PRINTS PR00412 Epoxide hydrolase signature 61 79 8.7E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS20040 fd93568f43e7c531ea3fc9dee11ed335 327 PRINTS PR00412 Epoxide hydrolase signature 297 319 8.7E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 SUPERFAMILY SSF81593 842 993 8.63E-37 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Pfam PF08335 GlnD PII-uridylyltransferase 849 992 4.4E-22 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Pfam PF08335 GlnD PII-uridylyltransferase 336 483 4.1E-34 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:1.10.4050.10 63 169 2.6E-16 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:1.10.4050.10 563 673 3.7E-17 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:1.20.120.330 324 487 3.2E-43 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:1.20.120.330 839 994 3.7E-44 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 SUPERFAMILY SSF81301 561 833 1.34E-65 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 86 983 17.123 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 90 315 3.0E-33 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 589 828 4.9E-72 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:3.30.460.10 177 323 5.8E-49 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 Gene3D G3DSA:3.30.460.10 674 835 1.6E-52 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 SUPERFAMILY SSF81593 329 483 1.41E-33 T 28-03-2018 CP478_RS12070 6374914a388cdbe4a4934aaa2ca08a05 994 SUPERFAMILY SSF81301 75 324 3.07E-58 T 28-03-2018 CP478_RS13405 4d117dfe07dffa5e5f6753c2960a7796 201 Pfam PF12804 MobA-like NTP transferase domain 13 166 1.8E-28 T 28-03-2018 IPR025877 MobA-like NTP transferase CP478_RS13405 4d117dfe07dffa5e5f6753c2960a7796 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 9 196 22.022 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CP478_RS13405 4d117dfe07dffa5e5f6753c2960a7796 201 Gene3D G3DSA:3.90.550.10 4 197 1.5E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS13405 4d117dfe07dffa5e5f6753c2960a7796 201 SUPERFAMILY SSF53448 11 192 3.75E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 SUPERFAMILY SSF56112 100 163 5.05E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 SUPERFAMILY SSF56112 196 372 5.05E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 Pfam PF03109 ABC1 family 118 232 7.9E-34 T 28-03-2018 IPR004147 UbiB domain CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 Pfam PF01636 Phosphotransferase enzyme family 256 312 2.0E-7 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 Gene3D G3DSA:1.10.510.10 251 370 1.7E-7 T 28-03-2018 CP478_RS17515 900a6477f7880405afeb8e5317450b5e 447 Gene3D G3DSA:3.30.200.20 107 244 1.7E-23 T 28-03-2018 CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 207 271 2.9E-13 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 46 111 4.0E-10 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 SUPERFAMILY SSF50249 144 276 1.44E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 SUPERFAMILY SSF50249 2 119 1.03E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 Gene3D G3DSA:2.40.50.140 49 116 6.2E-16 T 28-03-2018 CP478_RS19245 ac6e3561e1a75ce90d92b9031b9bb3fd 303 Gene3D G3DSA:2.40.50.140 210 279 2.4E-18 T 28-03-2018 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 142 30.326 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 70 1.0E-13 T 28-03-2018 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 Gene3D G3DSA:3.30.1550.10 5 73 3.9E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 SUPERFAMILY SSF54747 4 74 1.7E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 SUPERFAMILY SSF46906 69 142 1.44E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 SMART SM00649 11 142 1.1E-85 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 2.3E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 2.0E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 2.5E-63 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 Gene3D G3DSA:1.10.10.250 74 142 4.5E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03460 211796f7fa29a0172e901e1d9bdbff96 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 Gene3D G3DSA:3.40.50.720 108 258 4.1E-9 T 28-03-2018 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 105 3.7E-14 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 Gene3D G3DSA:3.40.50.720 2 106 5.6E-23 T 28-03-2018 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 Gene3D G3DSA:3.50.30.10 735 846 2.0E-29 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 SUPERFAMILY SSF52009 735 836 1.15E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 Pfam PF00391 PEP-utilising enzyme, mobile domain 761 832 1.8E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS11165 faaff23ea3388ce35b2df6c18652ab0d 854 SUPERFAMILY SSF51735 2 252 1.41E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PRINTS PR00958 Homoserine kinase signature 20 35 7.0E-38 T 28-03-2018 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PRINTS PR00958 Homoserine kinase signature 184 201 7.0E-38 T 28-03-2018 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PRINTS PR00958 Homoserine kinase signature 141 154 7.0E-38 T 28-03-2018 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PRINTS PR00958 Homoserine kinase signature 103 118 7.0E-38 T 28-03-2018 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PRINTS PR00958 Homoserine kinase signature 261 276 7.0E-38 T 28-03-2018 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 PIRSF PIRSF000676 10 302 1.2E-78 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 SUPERFAMILY SSF54211 16 159 9.87E-27 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 Hamap MF_00384 Homoserine kinase [thrB]. 13 307 27.94 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 Gene3D G3DSA:3.30.70.890 177 296 4.8E-20 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 SUPERFAMILY SSF55060 180 280 3.6E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 Gene3D G3DSA:3.30.230.10 12 176 2.0E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 Pfam PF00288 GHMP kinases N terminal domain 90 154 2.2E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 TIGRFAM TIGR00191 thrB: homoserine kinase 17 281 2.2E-58 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CP478_RS07095 22b32d0901df49508f0ec2a271f73d4d 316 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CP478_RS13725 0bfb435672ca5330e47dd6fedf19a94b 215 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 37.901 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 CP478_RS13725 0bfb435672ca5330e47dd6fedf19a94b 215 Pfam PF00929 Exonuclease 6 169 8.2E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS13725 0bfb435672ca5330e47dd6fedf19a94b 215 SMART SM00479 4 179 3.3E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS13725 0bfb435672ca5330e47dd6fedf19a94b 215 SUPERFAMILY SSF53098 4 178 9.87E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS13725 0bfb435672ca5330e47dd6fedf19a94b 215 Gene3D G3DSA:3.30.420.10 1 179 2.5E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS21065 8412930777dad21c65ee64a03fd5335b 157 SUPERFAMILY SSF89562 8 157 6.93E-45 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CP478_RS21065 8412930777dad21c65ee64a03fd5335b 157 Gene3D G3DSA:3.50.30.40 2 157 2.2E-41 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CP478_RS21065 8412930777dad21c65ee64a03fd5335b 157 TIGRFAM TIGR01935 NOT-MenG: RraA family 8 157 1.5E-64 T 28-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 CP478_RS21065 8412930777dad21c65ee64a03fd5335b 157 Pfam PF03737 Aldolase/RraA 8 156 1.5E-41 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 Gene3D G3DSA:3.40.50.300 469 658 2.2E-6 T 28-03-2018 CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 461 616 2.13E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 198 269 2.13E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 38 92 2.13E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 407 421 2.13E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 208 252 4.63E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SUPERFAMILY SSF52540 8 120 4.63E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SMART SM00491 497 626 9.0E-45 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 Pfam PF13307 Helicase C-terminal domain 480 639 6.9E-27 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 Gene3D G3DSA:3.40.50.300 23 436 5.9E-26 T 28-03-2018 CP478_RS07290 76486adeaae5957bf9d05e78ab4e2497 664 SMART SM00487 21 286 1.0E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Pfam PF00009 Elongation factor Tu GTP binding domain 23 286 1.4E-37 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF54211 501 616 8.85E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SMART SM00838 621 709 1.4E-25 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Pfam PF14492 Elongation Factor G, domain II 425 497 1.7E-23 T 28-03-2018 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Gene3D G3DSA:3.40.50.300 19 293 1.5E-40 T 28-03-2018 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Pfam PF03764 Elongation factor G, domain IV 501 617 1.3E-40 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Gene3D G3DSA:3.30.70.870 422 511 1.2E-18 T 28-03-2018 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF54980 425 502 3.91E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 154 3.9E-15 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SMART SM00889 501 619 4.7E-59 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Gene3D G3DSA:3.30.70.240 630 707 4.5E-22 T 28-03-2018 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Pfam PF00679 Elongation factor G C-terminus 621 706 5.1E-23 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF52540 23 287 1.2E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Gene3D G3DSA:2.40.30.10 303 421 3.6E-30 T 28-03-2018 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Pfam PF03144 Elongation factor Tu domain 2 329 411 2.5E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF50447 310 422 3.28E-22 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF50447 254 280 3.28E-22 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 Gene3D G3DSA:3.30.230.10 512 629 1.7E-38 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS00660 b60c4c1a251eeb84e47599f4b3118c32 714 SUPERFAMILY SSF54980 624 709 6.23E-22 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS11445 2d0f2abf17c5921e879ae75ac68a8e7b 144 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 142 1.9E-47 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS11445 2d0f2abf17c5921e879ae75ac68a8e7b 144 Pfam PF01850 PIN domain 3 133 8.8E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS11445 2d0f2abf17c5921e879ae75ac68a8e7b 144 Gene3D G3DSA:3.40.50.1010 3 137 4.7E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS11445 2d0f2abf17c5921e879ae75ac68a8e7b 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 17.083 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS11445 2d0f2abf17c5921e879ae75ac68a8e7b 144 SUPERFAMILY SSF88723 1 137 3.92E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01520 367a37291ce394f1f59e085739a014e3 302 Pfam PF04072 Leucine carboxyl methyltransferase 18 198 1.7E-60 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS01520 367a37291ce394f1f59e085739a014e3 302 Gene3D G3DSA:3.40.50.150 1 280 3.0E-53 T 28-03-2018 CP478_RS01520 367a37291ce394f1f59e085739a014e3 302 SUPERFAMILY SSF53335 14 283 3.65E-69 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01520 367a37291ce394f1f59e085739a014e3 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 279 2.6E-84 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 117 5.4E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 367 2.4E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 SUPERFAMILY SSF47203 223 368 1.61E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 Gene3D G3DSA:1.10.540.10 1 111 3.7E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 SUPERFAMILY SSF56645 1 214 1.96E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 Gene3D G3DSA:2.40.110.10 112 215 9.6E-8 T 28-03-2018 CP478_RS19165 b41aa5043043f1eba4d248c945b46607 373 Gene3D G3DSA:1.20.140.10 226 372 3.1E-28 T 28-03-2018 CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 Pfam PF00106 short chain dehydrogenase 54 246 3.4E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 54 242 4.3E-4 T 28-03-2018 CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 SUPERFAMILY SSF51735 52 287 5.57E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 226 1.1E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 72 1.1E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 197 1.1E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 143 1.1E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 245 1.1E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 Gene3D G3DSA:3.40.50.720 52 336 7.7E-55 T 28-03-2018 CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 143 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 207 226 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08455 78ec5b07a771f55768a1a1a0465a5ac0 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 187 195 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Pfam PF02811 PHP domain 48 219 3.1E-30 T 28-03-2018 IPR004013 PHP domain GO:0003824 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 SUPERFAMILY SSF89550 47 303 6.18E-23 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Gene3D G3DSA:2.40.50.140 978 1071 1.2E-5 T 28-03-2018 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Gene3D G3DSA:1.10.150.280 838 909 3.4E-4 T 28-03-2018 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 SMART SM00481 47 114 4.0E-26 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 338 749 2.6E-142 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Gene3D G3DSA:3.20.20.140 44 276 6.5E-39 T 28-03-2018 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 47 915 7.0E-196 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 46 1079 12.994 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS18455 9063f2f33b082cd0cafcaf745e23818c 1079 Pfam PF14579 Helix-hairpin-helix motif 825 913 2.2E-25 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS04860 430f60f84efbd634fd61ae090c398906 285 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 87 237 2.1E-11 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS04860 430f60f84efbd634fd61ae090c398906 285 Gene3D G3DSA:3.30.70.1230 88 256 1.6E-29 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS04860 430f60f84efbd634fd61ae090c398906 285 SMART SM00044 34 228 0.0019 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS04860 430f60f84efbd634fd61ae090c398906 285 SUPERFAMILY SSF55073 86 258 1.35E-40 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS16550 79e4e8d0ccd0d4ec5fbe824f60152cbe 393 SUPERFAMILY SSF53383 2 378 7.98E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS16550 79e4e8d0ccd0d4ec5fbe824f60152cbe 393 Gene3D G3DSA:3.40.640.10 13 245 4.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS16550 79e4e8d0ccd0d4ec5fbe824f60152cbe 393 Gene3D G3DSA:3.90.1150.10 246 375 1.7E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS16550 79e4e8d0ccd0d4ec5fbe824f60152cbe 393 PIRSF PIRSF005572 1 385 3.2E-111 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CP478_RS16550 79e4e8d0ccd0d4ec5fbe824f60152cbe 393 Pfam PF00266 Aminotransferase class-V 3 369 2.4E-62 T 28-03-2018 IPR000192 Aminotransferase class V domain CP478_RS18850 a5b49bdef694afb3f5e7834d7285bbee 100 Gene3D G3DSA:1.10.287.1060 4 100 1.3E-15 T 28-03-2018 CP478_RS18850 a5b49bdef694afb3f5e7834d7285bbee 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 95 1.5E-21 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS18850 a5b49bdef694afb3f5e7834d7285bbee 100 Pfam PF06013 Proteins of 100 residues with WXG 17 92 2.2E-10 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS18850 a5b49bdef694afb3f5e7834d7285bbee 100 SUPERFAMILY SSF140453 6 98 3.53E-21 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Gene3D G3DSA:3.30.300.10 279 403 1.8E-45 T 28-03-2018 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 SUPERFAMILY SSF55973 126 252 6.28E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 SUPERFAMILY SSF55973 6 114 5.89E-41 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 279 287 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Pfam PF02772 S-adenosylmethionine synthetase, central domain 130 251 2.2E-44 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 403 56.953 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 PIRSF PIRSF000497 1 403 1.2E-159 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 SUPERFAMILY SSF55973 253 401 2.94E-66 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 403 1.5E-162 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 131 141 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Gene3D G3DSA:3.30.300.10 13 152 2.6E-38 T 28-03-2018 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Gene3D G3DSA:3.30.300.10 159 278 1.0E-39 T 28-03-2018 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 7 106 3.0E-37 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS07630 7ce98ff9aa6bef65c8e1ebff9d15357b 403 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 253 392 3.4E-65 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF51735 471 639 2.17E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Gene3D G3DSA:3.40.50.720 668 899 4.3E-32 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Pfam PF08659 KR domain 670 840 4.5E-34 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Gene3D G3DSA:3.30.70.250 237 282 7.2E-8 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF52151 291 384 1.12E-46 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF52151 97 227 1.12E-46 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 ProSitePatterns PS00012 Phosphopantetheine attachment site. 945 960 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Gene3D G3DSA:3.40.366.10 283 389 8.3E-17 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Gene3D G3DSA:3.40.366.10 93 236 2.9E-28 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF55048 227 289 2.88E-5 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Pfam PF00698 Acyl transferase domain 99 404 4.5E-48 T 28-03-2018 IPR014043 Acyl transferase CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SMART SM00823 Phosphopantetheine attachment site 918 974 5.0E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF47336 917 987 6.81E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 100 403 2.2E-61 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 667 842 1.8E-9 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 SUPERFAMILY SSF51735 669 878 1.83E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Gene3D G3DSA:1.10.1200.10 900 999 1.3E-13 T 28-03-2018 CP478_RS12980 f92fa84b09bc362d0ac36abb035873d3 1004 Pfam PF00550 Phosphopantetheine attachment site 919 977 4.7E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 7.8E-101 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 SUPERFAMILY SSF75625 3 246 1.02E-87 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 Pfam PF01709 Transcriptional regulator 5 238 5.3E-88 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.243 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 Gene3D G3DSA:1.10.10.200 1 78 5.1E-28 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 Gene3D G3DSA:3.30.70.980 84 177 1.8E-29 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS14265 c4bb64d942b80c13b143bb08573ff60b 251 Gene3D G3DSA:3.30.70.980 178 249 1.1E-11 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 SUPERFAMILY SSF46946 122 187 9.86E-18 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 186 6.2E-11 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 Gene3D G3DSA:1.10.8.50 118 255 1.4E-45 T 28-03-2018 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 SUPERFAMILY SSF81624 2 124 1.44E-24 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 Gene3D G3DSA:3.20.190.10 1 117 3.9E-25 T 28-03-2018 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 93 2.0E-11 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 SMART SM00898 2 109 3.3E-16 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 ProSitePatterns PS01242 Zinc finger FPG-type signature. 230 254 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 SMART SM01232 123 211 1.1E-20 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS18065 441d994ccd93b228759047e200897cdc 255 SUPERFAMILY SSF57716 215 254 2.22E-10 T 28-03-2018 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 SUPERFAMILY SSF47203 234 399 1.43E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Gene3D G3DSA:2.40.110.10 127 231 2.1E-32 T 28-03-2018 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Gene3D G3DSA:1.10.540.10 1 126 7.8E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 397 2.3E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 124 6.0E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Gene3D G3DSA:1.20.140.10 232 406 2.0E-33 T 28-03-2018 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 SUPERFAMILY SSF56645 2 245 3.27E-74 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS10520 f8bf2c3063164cc06713cabec92ab90c 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 219 3.1E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 228 247 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 101 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 172 184 1.4E-21 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 ProSitePatterns PS00761 Signal peptidases I signature 3. 233 246 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 94 101 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 Gene3D G3DSA:2.10.109.10 81 293 1.7E-45 T 28-03-2018 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 Pfam PF00717 Peptidase S24-like 92 138 4.1E-8 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 Pfam PF10502 Signal peptidase, peptidase S26 163 251 2.0E-5 T 28-03-2018 IPR019533 Peptidase S26 CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 SUPERFAMILY SSF51306 167 289 1.15E-47 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 SUPERFAMILY SSF51306 84 136 1.15E-47 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CP478_RS15860 40a51012a7abf8bb2e50ed739dce7f9a 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 71 278 1.3E-36 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CP478_RS01010 6b0d8cb979b568edbd397df7337bacbd 169 TIGRFAM TIGR04338 HEXXH_Rv0185: putative metallohydrolase, TIGR04338 family 8 168 5.8E-72 T 28-03-2018 IPR027595 Conserved hypothetical protein CHP04338 CP478_RS17190 3f0e17e1b5791cd8d3679db41a6de9d4 362 Gene3D G3DSA:3.20.20.70 63 282 4.4E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS17190 3f0e17e1b5791cd8d3679db41a6de9d4 362 PIRSF PIRSF004869 5 317 1.5E-89 T 28-03-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted CP478_RS17190 3f0e17e1b5791cd8d3679db41a6de9d4 362 SUPERFAMILY SSF102114 52 320 1.94E-38 T 28-03-2018 CP478_RS17190 3f0e17e1b5791cd8d3679db41a6de9d4 362 Pfam PF04055 Radical SAM superfamily 84 235 6.8E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS17190 3f0e17e1b5791cd8d3679db41a6de9d4 362 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 9 355 2.8E-194 T 28-03-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme CP478_RS03200 993ab00a9525837d0da9c960ea1afcc6 137 Pfam PF01850 PIN domain 7 126 2.4E-12 T 28-03-2018 IPR002716 PIN domain CP478_RS03200 993ab00a9525837d0da9c960ea1afcc6 137 Gene3D G3DSA:3.40.50.1010 4 137 2.4E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03200 993ab00a9525837d0da9c960ea1afcc6 137 SUPERFAMILY SSF88723 6 134 7.85E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03200 993ab00a9525837d0da9c960ea1afcc6 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 133 15.075 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS08640 ea4ad2d73e5f105a9964fd56d3b35b48 156 Pfam PF05119 Phage terminase, small subunit 48 142 2.0E-25 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CP478_RS08640 ea4ad2d73e5f105a9964fd56d3b35b48 156 ProSitePatterns PS00221 MIP family signature. 106 114 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CP478_RS08640 ea4ad2d73e5f105a9964fd56d3b35b48 156 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 39 151 2.3E-35 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 Gene3D G3DSA:3.40.50.10540 398 801 8.7E-95 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 Gene3D G3DSA:3.40.50.10540 3 389 6.8E-80 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 SUPERFAMILY SSF89796 6 385 7.98E-76 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 Pfam PF02515 CoA-transferase family III 402 772 2.2E-93 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 Pfam PF02515 CoA-transferase family III 8 378 5.0E-70 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CP478_RS10140 078079365571ef91cff1011aa7fd1051 804 SUPERFAMILY SSF89796 400 796 1.31E-89 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS09880 f1d8cf785172d32038dfb4cc97f16af0 221 SUPERFAMILY SSF50494 34 197 2.0E-18 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS09880 f1d8cf785172d32038dfb4cc97f16af0 221 Gene3D G3DSA:2.40.10.10 32 122 2.3E-11 T 28-03-2018 CP478_RS09880 f1d8cf785172d32038dfb4cc97f16af0 221 Gene3D G3DSA:2.40.10.10 126 197 0.0014 T 28-03-2018 CP478_RS19840 448eaae5e8832c931bd5fa4aff8639a0 314 Gene3D G3DSA:3.90.25.10 172 314 3.8E-41 T 28-03-2018 CP478_RS19840 448eaae5e8832c931bd5fa4aff8639a0 314 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 7.1E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19840 448eaae5e8832c931bd5fa4aff8639a0 314 SUPERFAMILY SSF51735 2 311 1.87E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19840 448eaae5e8832c931bd5fa4aff8639a0 314 Gene3D G3DSA:3.40.50.720 1 171 1.3E-34 T 28-03-2018 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 611 628 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 107 2.5E-39 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Gene3D G3DSA:3.40.50.20 2 121 3.3E-47 T 28-03-2018 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 SMART SM00878 329 445 5.5E-43 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Gene3D G3DSA:3.30.1490.20 122 198 2.2E-11 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Gene3D G3DSA:3.30.470.20 199 448 5.1E-88 T 28-03-2018 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 317 7.3E-57 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Gene3D G3DSA:2.40.50.100 579 655 7.0E-19 T 28-03-2018 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Pfam PF02785 Biotin carboxylase C-terminal domain 329 445 2.7E-27 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 SUPERFAMILY SSF51230 586 655 4.32E-21 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 SUPERFAMILY SSF56059 81 326 4.6E-54 T 28-03-2018 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 SUPERFAMILY SSF52440 3 111 5.32E-41 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 SUPERFAMILY SSF51246 324 447 1.1E-30 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 281 288 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS05310 1084e81b97130d06ffcce905e2014e47 667 Pfam PF00364 Biotin-requiring enzyme 590 653 9.1E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS09205 8b5a32cbf965e00a2d14e6db91b45a17 239 Pfam PF01061 ABC-2 type transporter 12 201 5.8E-31 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CP478_RS09205 8b5a32cbf965e00a2d14e6db91b45a17 239 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 15 238 1.6E-85 T 28-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 CP478_RS09205 8b5a32cbf965e00a2d14e6db91b45a17 239 PIRSF PIRSF006648 1 239 1.3E-19 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CP478_RS12270 588f5f2c712562eb7ee5a32c8a1334ba 72 Pfam PF01037 Lrp/AsnC ligand binding domain 1 69 3.7E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CP478_RS12270 588f5f2c712562eb7ee5a32c8a1334ba 72 Gene3D G3DSA:3.30.70.920 1 67 1.6E-10 T 28-03-2018 CP478_RS12270 588f5f2c712562eb7ee5a32c8a1334ba 72 SUPERFAMILY SSF54909 1 70 8.18E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 Gene3D G3DSA:3.40.470.10 2 227 2.4E-79 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 SMART SM00986 53 214 9.8E-33 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 SMART SM00987 53 214 9.8E-33 T 28-03-2018 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 Pfam PF03167 Uracil DNA glycosylase superfamily 55 213 1.1E-17 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 SUPERFAMILY SSF52141 9 226 5.23E-74 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 225 34.31 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS16275 39869c4a5600abfc37e96b1754433ab1 227 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 13 216 4.3E-61 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 SUPERFAMILY SSF56601 78 452 8.71E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 332 346 2.3E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 347 361 2.3E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 110 129 2.3E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 415 428 2.3E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 275 297 2.3E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 97 232 3.6E-47 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 231 438 5.8E-81 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 Gene3D G3DSA:3.40.710.10 68 455 1.3E-29 T 28-03-2018 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 73 238 2.7E-53 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS19805 2760f5dd41631f333f39a360d0c62593 461 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 239 453 4.8E-78 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CP478_RS11150 de50f24777649450adeb2064df80cebe 105 Pfam PF10861 Protein of Unknown function (DUF2784) 1 99 2.7E-31 T 28-03-2018 IPR021218 Protein of unknown function DUF2784 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Pfam PF00175 Oxidoreductase NAD-binding domain 456 562 1.7E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 SUPERFAMILY SSF63380 341 439 3.05E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 632 640 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Gene3D G3DSA:2.40.30.10 335 430 3.2E-19 T 28-03-2018 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Pfam PF00970 Oxidoreductase FAD-binding domain 344 439 2.2E-12 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 SUPERFAMILY SSF54292 571 682 3.1E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Gene3D G3DSA:3.40.50.80 431 573 2.9E-27 T 28-03-2018 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Gene3D G3DSA:3.10.20.30 574 685 1.7E-25 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 SUPERFAMILY SSF52343 443 580 1.31E-31 T 28-03-2018 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 601 675 8.1E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS19425 49cc52fb7503f4852bde7bfa1774d4e3 685 Pfam PF00487 Fatty acid desaturase 67 299 9.7E-36 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CP478_RS04225 5301327020889250a82422efcbb34825 472 Pfam PF00206 Lyase 30 296 5.2E-24 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CP478_RS04225 5301327020889250a82422efcbb34825 472 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CP478_RS04225 5301327020889250a82422efcbb34825 472 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 449 8.8E-14 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04225 5301327020889250a82422efcbb34825 472 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 7.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS04225 5301327020889250a82422efcbb34825 472 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 7.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS04225 5301327020889250a82422efcbb34825 472 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 7.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS04225 5301327020889250a82422efcbb34825 472 Gene3D G3DSA:1.10.275.10 5 98 1.0E-14 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CP478_RS04225 5301327020889250a82422efcbb34825 472 SMART SM00998 365 450 2.3E-22 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04225 5301327020889250a82422efcbb34825 472 Gene3D G3DSA:1.20.200.10 99 378 3.2E-57 T 28-03-2018 CP478_RS04225 5301327020889250a82422efcbb34825 472 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 450 3.4E-145 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04225 5301327020889250a82422efcbb34825 472 Gene3D G3DSA:1.10.40.30 379 449 1.1E-16 T 28-03-2018 CP478_RS04225 5301327020889250a82422efcbb34825 472 SUPERFAMILY SSF48557 6 451 5.65E-82 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 404 571 7.5E-49 T 28-03-2018 IPR001162 UvrC family homology region CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Pfam PF01541 GIY-YIG catalytic domain 18 92 2.5E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SUPERFAMILY SSF82771 18 101 1.31E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Gene3D G3DSA:1.10.150.20 583 643 8.2E-16 T 28-03-2018 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 618 1.1E-149 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SMART SM00278 585 604 200.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SMART SM00278 617 636 1.4 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SMART SM00465 17 99 1.0E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SUPERFAMILY SSF46600 194 247 6.93E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Gene3D G3DSA:4.10.860.10 187 248 8.1E-15 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Pfam PF02151 UvrB/uvrC motif 210 242 8.7E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 SUPERFAMILY SSF47781 519 638 4.77E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 636 30.821 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Gene3D G3DSA:3.40.1440.10 6 102 1.2E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS07770 8a6917c4e4bf5c6cf938f9665d94b8f1 646 Pfam PF12826 Helix-hairpin-helix motif 590 638 1.4E-9 T 28-03-2018 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 Gene3D G3DSA:1.20.1640.10 720 926 1.4E-24 T 28-03-2018 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 Gene3D G3DSA:1.20.1640.10 142 370 5.0E-27 T 28-03-2018 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 TIGRFAM TIGR00833 actII: transport protein 21 929 3.1E-297 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 SUPERFAMILY SSF82866 726 929 1.31E-25 T 28-03-2018 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 Pfam PF03176 MMPL family 54 382 8.7E-111 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 Pfam PF03176 MMPL family 602 937 2.1E-105 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02715 b224943bd4df81f4b178e444bd4e6dba 968 SUPERFAMILY SSF82866 134 350 1.14E-25 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Gene3D G3DSA:3.10.150.10 265 400 6.4E-33 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 SMART SM00480 29 380 2.3E-137 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 SUPERFAMILY SSF55979 15 130 6.28E-23 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 SUPERFAMILY SSF55979 262 400 8.24E-26 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 PIRSF PIRSF000804 13 401 6.9E-89 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Gene3D G3DSA:3.10.150.10 1 133 5.4E-32 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 15 400 2.5E-110 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 SUPERFAMILY SSF55979 139 263 1.49E-16 T 28-03-2018 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Pfam PF02767 DNA polymerase III beta subunit, central domain 139 260 1.9E-33 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 14 130 1.7E-36 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 371 1.2E-33 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS00010 113888c3dbad96b1f4c37f848b93071c 402 Gene3D G3DSA:3.10.150.10 134 264 3.7E-29 T 28-03-2018 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 50.408 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Gene3D G3DSA:2.40.30.20 6 85 3.0E-31 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 6.9E-17 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Gene3D G3DSA:1.20.150.20 384 511 1.2E-52 T 28-03-2018 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Gene3D G3DSA:3.40.50.300 86 375 1.1E-107 T 28-03-2018 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.1E-49 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 9.5E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 SUPERFAMILY SSF52540 99 381 1.7E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 SUPERFAMILY SSF47917 383 511 4.19E-47 T 28-03-2018 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.7E-258 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 SUPERFAMILY SSF50615 14 97 2.75E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07165 d1c7b618557bc756433ffa539b8417e0 549 PIRSF PIRSF039088 4 514 6.9E-233 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 Pfam PF00106 short chain dehydrogenase 10 186 5.7E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 Gene3D G3DSA:3.40.50.720 8 241 8.6E-51 T 28-03-2018 CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 SUPERFAMILY SSF51735 6 234 2.77E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02580 26845d6fc2d05b18ef24a69ef2772e84 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07335 18fa6954387934908f0b253dce215d20 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 1.7E-30 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 Hamap MF_00258 Glutamate racemase [murI]. 6 258 36.668 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 Gene3D G3DSA:3.40.50.1860 4 122 1.3E-25 T 28-03-2018 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 Gene3D G3DSA:3.40.50.1860 123 270 1.0E-44 T 28-03-2018 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 SUPERFAMILY SSF53681 7 109 2.81E-31 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 254 1.8E-65 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07335 18fa6954387934908f0b253dce215d20 271 SUPERFAMILY SSF53681 111 257 5.23E-39 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS19035 35274d1da17e027b04377246d8d5688b 497 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 8 298 1.1E-103 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS19035 35274d1da17e027b04377246d8d5688b 497 Gene3D G3DSA:3.30.559.10 28 161 0.001 T 28-03-2018 CP478_RS19035 35274d1da17e027b04377246d8d5688b 497 SUPERFAMILY SSF52777 76 156 5.45E-5 T 28-03-2018 CP478_RS19035 35274d1da17e027b04377246d8d5688b 497 Pfam PF06974 Protein of unknown function (DUF1298) 338 486 9.4E-35 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS19035 35274d1da17e027b04377246d8d5688b 497 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 8 489 2.6E-129 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS14150 a30c9caf68e4d55538cf746488227260 308 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 156 171 2.3E-6 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS14150 a30c9caf68e4d55538cf746488227260 308 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 236 251 2.3E-6 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS14150 a30c9caf68e4d55538cf746488227260 308 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 143 305 1.0E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS14150 a30c9caf68e4d55538cf746488227260 308 SUPERFAMILY SSF50891 142 306 2.48E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS14150 a30c9caf68e4d55538cf746488227260 308 Gene3D G3DSA:2.40.100.10 124 307 2.0E-42 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS15145 18b1359cd2fd59606f7db52c7edfc429 245 Gene3D G3DSA:3.40.50.1820 3 242 6.0E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15145 18b1359cd2fd59606f7db52c7edfc429 245 SUPERFAMILY SSF53474 1 241 5.36E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15145 18b1359cd2fd59606f7db52c7edfc429 245 Pfam PF01738 Dienelactone hydrolase family 17 242 1.4E-65 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 Pfam PF07883 Cupin domain 14 74 2.8E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 SMART SM00342 163 245 2.1E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 Gene3D G3DSA:2.60.120.10 2 130 5.8E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 SUPERFAMILY SSF46689 199 248 5.38E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 Pfam PF12833 Helix-turn-helix domain 172 244 2.1E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 SUPERFAMILY SSF51182 11 168 1.6E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 Gene3D G3DSA:1.10.10.60 145 198 3.7E-17 T 28-03-2018 CP478_RS20935 36d40b7fab48f51df3939239acf93b50 263 Gene3D G3DSA:1.10.10.60 199 252 1.7E-7 T 28-03-2018 CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 SUPERFAMILY SSF55326 411 581 1.01E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 754 307.993 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 751 2.7E-252 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 PIRSF PIRSF001587 6 754 2.7E-279 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Pfam PF02769 AIR synthase related protein, C-terminal domain 588 725 9.0E-22 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Pfam PF02769 AIR synthase related protein, C-terminal domain 212 368 2.5E-35 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Gene3D G3DSA:3.30.1330.10 407 579 5.4E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Gene3D G3DSA:3.30.1330.10 22 204 3.1E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Gene3D G3DSA:3.90.650.10 583 754 1.9E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Gene3D G3DSA:3.90.650.10 209 386 4.1E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Pfam PF00586 AIR synthase related protein, N-terminal domain 470 574 2.0E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 Pfam PF00586 AIR synthase related protein, N-terminal domain 97 198 3.8E-24 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 SUPERFAMILY SSF55326 18 204 2.54E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 SUPERFAMILY SSF56042 211 441 8.37E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04360 43519a8e286c7504854d7eaa9f787b48 754 SUPERFAMILY SSF56042 587 753 1.18E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.7E-9 T 28-03-2018 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 128 146 2.7E-9 T 28-03-2018 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 2.7E-9 T 28-03-2018 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 SUPERFAMILY SSF51905 340 402 3.97E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 SUPERFAMILY SSF51905 10 224 3.97E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 Gene3D G3DSA:1.20.58.100 410 517 1.0E-17 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 SUPERFAMILY SSF46977 424 514 3.53E-17 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 Pfam PF00890 FAD binding domain 11 381 3.4E-88 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 SUPERFAMILY SSF56425 227 341 1.29E-32 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 359 366 2.9E-6 T 28-03-2018 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.9E-6 T 28-03-2018 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 497 3.6E-212 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 498 2.2E-5 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 Gene3D G3DSA:3.50.50.60 296 397 2.4E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08730 55f12f15f3c44b554060ad6cb8cbf4b4 527 Gene3D G3DSA:3.50.50.60 1 295 1.6E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12605 15067549bada79c2cb80962e97ef31bc 174 Gene3D G3DSA:3.40.50.300 14 128 1.7E-5 T 28-03-2018 CP478_RS12605 15067549bada79c2cb80962e97ef31bc 174 SUPERFAMILY SSF52540 33 124 2.34E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00830 a21d6b94c9ab465a44c04f02c285aa05 74 SUPERFAMILY SSF140459 8 73 1.05E-19 T 28-03-2018 CP478_RS00830 a21d6b94c9ab465a44c04f02c285aa05 74 Pfam PF00934 PE family 1 73 1.1E-24 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 4.1E-59 T 28-03-2018 CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 Gene3D G3DSA:3.40.50.720 50 255 1.7E-54 T 28-03-2018 CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 Gene3D G3DSA:3.40.50.720 1 49 1.0E-11 T 28-03-2018 CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 SUPERFAMILY SSF51735 4 252 1.01E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10560 86db40be99bd7cbcc5f42ff808d05455 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05785 c49036709ec7e3d2908c11f3cf6d09a1 104 SUPERFAMILY SSF56349 5 69 2.91E-7 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS05785 c49036709ec7e3d2908c11f3cf6d09a1 104 Gene3D G3DSA:1.10.443.10 2 93 2.8E-6 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS05785 c49036709ec7e3d2908c11f3cf6d09a1 104 PIRSF PIRSF004338 1 104 6.7E-65 T 28-03-2018 IPR014417 Integrase, predicted CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 312 2.7E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 8.7E-16 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.7E-16 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 8.7E-16 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 8.7E-16 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 Gene3D G3DSA:3.40.50.720 161 383 3.7E-28 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 Gene3D G3DSA:3.40.50.720 2 125 3.1E-14 T 28-03-2018 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 Gene3D G3DSA:3.50.50.60 126 160 0.016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 3.4E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.4E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 3.4E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS09865 22461b0ada5ee2a54d5b8382e6ebcb78 400 SUPERFAMILY SSF51905 3 339 2.88E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18700 18596cc801b205eb87226545b1581950 539 Gene3D G3DSA:1.10.560.10 1 183 6.7E-37 T 28-03-2018 IPR027413 GroEL-like equatorial domain CP478_RS18700 18596cc801b205eb87226545b1581950 539 SUPERFAMILY SSF48592 6 133 3.5E-68 T 28-03-2018 CP478_RS18700 18596cc801b205eb87226545b1581950 539 SUPERFAMILY SSF48592 404 521 3.5E-68 T 28-03-2018 CP478_RS18700 18596cc801b205eb87226545b1581950 539 Gene3D G3DSA:3.50.7.10 184 371 1.1E-80 T 28-03-2018 IPR027409 GroEL-like apical domain CP478_RS18700 18596cc801b205eb87226545b1581950 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 4.4E-87 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CP478_RS18700 18596cc801b205eb87226545b1581950 539 SUPERFAMILY SSF54849 136 202 3.2E-22 T 28-03-2018 CP478_RS18700 18596cc801b205eb87226545b1581950 539 PRINTS PR00298 60kDa chaperonin signature 26 52 1.4E-65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 PRINTS PR00298 60kDa chaperonin signature 396 417 1.4E-65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 PRINTS PR00298 60kDa chaperonin signature 266 289 1.4E-65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 PRINTS PR00298 60kDa chaperonin signature 348 373 1.4E-65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 PRINTS PR00298 60kDa chaperonin signature 82 109 1.4E-65 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 37.815 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS18700 18596cc801b205eb87226545b1581950 539 SUPERFAMILY SSF52029 183 374 1.94E-71 T 28-03-2018 IPR027409 GroEL-like apical domain CP478_RS18700 18596cc801b205eb87226545b1581950 539 Gene3D G3DSA:1.10.560.10 372 516 1.7E-24 T 28-03-2018 IPR027413 GroEL-like equatorial domain CP478_RS18700 18596cc801b205eb87226545b1581950 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 9.8E-213 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 SMART SM00836 429 550 3.9E-54 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Gene3D G3DSA:3.40.50.620 108 356 5.1E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Gene3D G3DSA:3.30.1360.70 3 107 6.4E-29 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 SUPERFAMILY SSF52374 116 438 1.24E-80 T 28-03-2018 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 SUPERFAMILY SSF47323 423 550 7.19E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 SUPERFAMILY SSF55190 5 113 1.22E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 16 93 1.4E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 25.398 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Gene3D G3DSA:1.10.730.10 395 550 4.9E-52 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 550 2.3E-123 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Pfam PF05746 DALR anticodon binding domain 429 550 6.8E-40 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 Pfam PF00750 tRNA synthetases class I (R) 120 390 2.0E-17 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 3.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 3.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 3.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 3.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS07070 b22e2ff5ca4319f76db9d34c02b05da7 550 SMART SM01016 4 93 4.4E-34 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 Gene3D G3DSA:3.40.50.1820 198 426 4.3E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 Pfam PF07859 alpha/beta hydrolase fold 235 416 6.0E-19 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 Pfam PF00934 PE family 3 93 1.3E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 SUPERFAMILY SSF53474 176 420 4.63E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 Gene3D G3DSA:1.10.287.1060 2 101 9.4E-5 T 28-03-2018 CP478_RS16945 505a5ccd891715c87b7fe7114e4e6419 437 SUPERFAMILY SSF140459 9 85 4.45E-24 T 28-03-2018 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 SUPERFAMILY SSF48498 80 185 5.26E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 181 7.3E-11 T 28-03-2018 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.6E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 Gene3D G3DSA:1.10.357.10 58 194 3.7E-17 T 28-03-2018 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 Gene3D G3DSA:1.10.10.60 2 57 2.5E-18 T 28-03-2018 CP478_RS01755 9971204ab3fdd421ba3dd26d5bf017e0 200 SUPERFAMILY SSF46689 4 75 2.26E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 Gene3D G3DSA:2.30.38.10 382 465 1.5E-19 T 28-03-2018 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 SUPERFAMILY SSF56801 5 576 2.35E-96 T 28-03-2018 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 Gene3D G3DSA:3.40.50.980 2 179 7.2E-29 T 28-03-2018 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 Pfam PF00501 AMP-binding enzyme 11 472 2.0E-73 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 Gene3D G3DSA:3.40.50.980 180 356 2.3E-30 T 28-03-2018 CP478_RS08385 6a549caab1f4735270d74e40dfc4c9bf 584 Gene3D G3DSA:3.30.300.30 466 574 6.9E-14 T 28-03-2018 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 Pfam PF00072 Response regulator receiver domain 23 132 2.9E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 SMART SM00862 169 243 1.5E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 SMART SM00448 21 132 3.8E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 SUPERFAMILY SSF52172 18 144 1.57E-42 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 Gene3D G3DSA:3.40.50.2300 8 142 2.6E-37 T 28-03-2018 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 243 4.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 SUPERFAMILY SSF46894 147 244 2.49E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS04125 349695f395ff0b2d3cc030483bdae110 247 Gene3D G3DSA:1.10.10.10 143 247 7.6E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 Gene3D G3DSA:3.40.190.10 96 187 4.6E-18 T 28-03-2018 CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 2.7E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 Gene3D G3DSA:3.40.190.10 188 284 3.3E-19 T 28-03-2018 CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 Gene3D G3DSA:1.10.10.10 5 90 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 SUPERFAMILY SSF46785 6 117 1.36E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 Pfam PF03466 LysR substrate binding domain 95 309 4.4E-44 T 28-03-2018 IPR005119 LysR, substrate-binding CP478_RS12400 28bb2e5aa1be315786e91eb2822d9f08 312 SUPERFAMILY SSF53850 97 308 3.93E-30 T 28-03-2018 CP478_RS08740 e9ffcfe821f8b1964feaaee318b86e3a 252 Pfam PF08241 Methyltransferase domain 53 140 3.6E-6 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS08740 e9ffcfe821f8b1964feaaee318b86e3a 252 Gene3D G3DSA:3.40.50.150 39 251 1.0E-12 T 28-03-2018 CP478_RS08740 e9ffcfe821f8b1964feaaee318b86e3a 252 SUPERFAMILY SSF53335 38 251 3.5E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Gene3D G3DSA:1.10.10.10 253 323 3.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Gene3D G3DSA:1.10.601.10 3 159 8.6E-67 T 28-03-2018 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Pfam PF04545 Sigma-70, region 4 258 311 2.9E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Gene3D G3DSA:1.10.10.10 160 210 2.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Pfam PF04539 Sigma-70 region 3 169 245 1.6E-25 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 SUPERFAMILY SSF88946 25 160 1.44E-50 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 283 309 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 SUPERFAMILY SSF88659 220 320 9.81E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 114 127 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 SUPERFAMILY SSF88659 163 236 5.67E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Pfam PF04542 Sigma-70 region 2 90 159 7.3E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 PRINTS PR00046 Major sigma-70 factor signature 138 146 1.2E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 PRINTS PR00046 Major sigma-70 factor signature 262 274 1.2E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 PRINTS PR00046 Major sigma-70 factor signature 283 298 1.2E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 PRINTS PR00046 Major sigma-70 factor signature 298 309 1.2E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 PRINTS PR00046 Major sigma-70 factor signature 114 127 1.2E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 Pfam PF00140 Sigma-70 factor, region 1.2 25 58 6.8E-12 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS14855 88b03b09fea8cfcfef19603dbde2a45e 323 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 86 311 4.5E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.3E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 PRINTS PR00986 Valyl-tRNA synthetase signature 439 460 1.3E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 PRINTS PR00986 Valyl-tRNA synthetase signature 347 360 1.3E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 1.3E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 PRINTS PR00986 Valyl-tRNA synthetase signature 470 488 1.3E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:1.10.730.10 528 745 4.0E-64 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 876 14.824 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 SUPERFAMILY SSF47323 582 825 4.11E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 SUPERFAMILY SSF52374 342 580 1.73E-132 T 28-03-2018 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 SUPERFAMILY SSF52374 3 192 1.73E-132 T 28-03-2018 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:1.10.287.380 804 874 2.0E-19 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:3.40.50.620 432 527 9.1E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Pfam PF08264 Anticodon-binding domain of tRNA 611 750 2.7E-36 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 426 6.1E-149 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 436 569 1.1E-46 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:3.90.740.10 236 431 7.7E-58 T 28-03-2018 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:3.90.740.10 195 235 2.8E-10 T 28-03-2018 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 SUPERFAMILY SSF50677 191 336 2.09E-52 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 811 875 3.2E-16 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 854 2.9E-299 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 Gene3D G3DSA:3.40.50.620 16 194 8.8E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS13380 e847c435a27bf97a14819fb9c8b8a07e 876 SUPERFAMILY SSF46589 811 875 1.83E-13 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 Pfam PF00464 Serine hydroxymethyltransferase 5 386 2.1E-157 T 28-03-2018 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 416 48.502 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 SUPERFAMILY SSF53383 3 416 1.97E-164 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 Gene3D G3DSA:3.40.640.10 34 270 4.3E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 Gene3D G3DSA:3.90.1150.10 271 415 1.0E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS06005 7c6d8393432f76ffa448dbdf701bf6f6 426 PIRSF PIRSF000412 1 416 2.2E-149 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 Gene3D G3DSA:3.40.47.10 270 416 3.8E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 SMART SM00825 Beta-ketoacyl synthase 14 407 1.4E-10 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 373 5.1E-30 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 Gene3D G3DSA:3.40.47.10 5 266 5.4E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 SUPERFAMILY SSF53901 13 259 4.45E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 SUPERFAMILY SSF53901 222 416 2.98E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12215 fe74783c26acc2130e93b574002ad770 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 253 2.0E-49 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS01565 ba6725dac0fd47740955e865cde3cf09 472 PIRSF PIRSF017804 1 472 2.5E-94 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS01565 ba6725dac0fd47740955e865cde3cf09 472 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 8 90 7.4E-22 T 28-03-2018 IPR024962 YukD-like CP478_RS01565 ba6725dac0fd47740955e865cde3cf09 472 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 471 1.9E-122 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 247 273 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 304 320 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 337 351 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 353 371 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 394 412 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 28 51 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00465 E-class P450 group IV signature 378 394 5.3E-33 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 Pfam PF00067 Cytochrome P450 17 440 1.3E-66 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 Gene3D G3DSA:1.10.630.10 2 450 1.9E-101 T 28-03-2018 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 SUPERFAMILY SSF48264 12 448 1.96E-96 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 387 396 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00385 P450 superfamily signature 385 394 2.7E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00385 P450 superfamily signature 256 273 2.7E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00385 P450 superfamily signature 394 405 2.7E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04160 6e69b0eb21619113d8c9b5b721b00e6d 451 PRINTS PR00385 P450 superfamily signature 309 320 2.7E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03815 bb96de5bb59cffe7236ee660ded417ad 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 80 95 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03815 bb96de5bb59cffe7236ee660ded417ad 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 21.537 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CP478_RS03815 bb96de5bb59cffe7236ee660ded417ad 100 SUPERFAMILY SSF54189 5 94 3.6E-32 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03815 bb96de5bb59cffe7236ee660ded417ad 100 Gene3D G3DSA:3.30.70.330 5 99 6.9E-31 T 28-03-2018 CP478_RS03815 bb96de5bb59cffe7236ee660ded417ad 100 Pfam PF00276 Ribosomal protein L23 9 91 5.4E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 SUPERFAMILY SSF140459 2 172 6.8E-58 T 28-03-2018 CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF00823 PPE family 5 161 4.8E-57 T 28-03-2018 IPR000030 PPE family CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Gene3D G3DSA:1.10.287.1060 19 107 7.0E-7 T 28-03-2018 CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 300 339 1.6E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 490 524 6.2E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 453 489 4.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 379 416 1.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 260 298 3.5E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 515 552 5.1E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 335 373 9.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08480 53d3286632c718ab1bdb00c061895908 678 Pfam PF01469 Pentapeptide repeats (8 copies) 220 259 4.4E-12 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS02675 ca318b1604a500dc6dc2b141decce4b3 78 Pfam PF12728 Helix-turn-helix domain 24 72 4.1E-14 T 28-03-2018 CP478_RS02675 ca318b1604a500dc6dc2b141decce4b3 78 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 24 71 2.9E-19 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CP478_RS02675 ca318b1604a500dc6dc2b141decce4b3 78 Gene3D G3DSA:1.10.1660.20 37 67 1.9E-11 T 28-03-2018 CP478_RS02675 ca318b1604a500dc6dc2b141decce4b3 78 SUPERFAMILY SSF46955 24 72 2.01E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS02675 ca318b1604a500dc6dc2b141decce4b3 78 Gene3D G3DSA:1.10.10.60 3 36 9.1E-4 T 28-03-2018 CP478_RS02310 bdb7cb44da91b4bf8b9c7b6c56a9c2e0 217 SMART SM00464 8 206 4.9E-46 T 28-03-2018 IPR003111 Lon, substrate-binding domain CP478_RS02310 bdb7cb44da91b4bf8b9c7b6c56a9c2e0 217 Gene3D G3DSA:2.30.130.40 7 116 1.3E-25 T 28-03-2018 CP478_RS02310 bdb7cb44da91b4bf8b9c7b6c56a9c2e0 217 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 204 4.4E-23 T 28-03-2018 IPR003111 Lon, substrate-binding domain CP478_RS02310 bdb7cb44da91b4bf8b9c7b6c56a9c2e0 217 SUPERFAMILY SSF88697 8 205 4.97E-39 T 28-03-2018 IPR015947 PUA-like domain CP478_RS05505 3158bb873dfe7eae84c30bd79ea5eabe 567 Gene3D G3DSA:3.20.20.80 87 455 4.5E-8 T 28-03-2018 CP478_RS05505 3158bb873dfe7eae84c30bd79ea5eabe 567 SUPERFAMILY SSF51445 110 208 4.21E-5 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS20845 dbbf89e9695d0dfd591a267c2bfe0c26 259 Gene3D G3DSA:3.40.1130.10 2 212 3.1E-44 T 28-03-2018 CP478_RS20845 dbbf89e9695d0dfd591a267c2bfe0c26 259 Pfam PF01553 Acyltransferase 22 150 4.7E-34 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS20845 dbbf89e9695d0dfd591a267c2bfe0c26 259 SUPERFAMILY SSF69593 13 204 1.83E-36 T 28-03-2018 CP478_RS20845 dbbf89e9695d0dfd591a267c2bfe0c26 259 SMART SM00563 37 153 1.3E-37 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1519 1906 6.1E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.30.559.10 1001 1231 5.9E-45 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:1.10.1200.10 1994 2066 1.6E-19 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 577 588 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF56801 1455 2003 9.55E-141 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:2.30.38.10 747 821 2.4E-4 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF52777 6 153 2.89E-5 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF00501 AMP-binding enzyme 473 828 7.1E-36 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF00501 AMP-binding enzyme 1499 1882 1.6E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:2.30.38.10 1794 1875 2.1E-21 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF56801 466 918 6.28E-65 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.40.50.980 584 746 7.2E-30 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.30.559.10 15 175 6.5E-4 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2014 2029 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.40.50.720 2105 2464 5.0E-29 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF47336 938 1035 1.14E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SMART SM00823 Phosphopantetheine attachment site 1990 2059 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF00668 Condensation domain 1023 1475 8.1E-85 T 28-03-2018 IPR001242 Condensation domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.40.50.980 1489 1640 4.4E-42 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.40.50.980 442 583 4.4E-10 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF52777 1212 1459 2.67E-55 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF47336 1982 2055 3.93E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:1.10.1200.10 940 1000 6.3E-7 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF52777 204 419 1.22E-6 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF13193 AMP-binding enzyme C-terminal domain 1890 1965 1.4E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2109 2511 2.8E-123 T 28-03-2018 IPR010080 Thioester reductase-like domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.30.300.30 824 939 1.1E-10 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.30.300.30 1877 1993 6.5E-35 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF07993 Male sterility protein 2112 2372 1.4E-59 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Gene3D G3DSA:3.40.50.980 1641 1783 4.8E-32 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF51735 2108 2426 4.56E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 SUPERFAMILY SSF52777 1025 1200 7.45E-49 T 28-03-2018 CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF00550 Phosphopantetheine attachment site 1992 2055 1.7E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 Pfam PF00550 Phosphopantetheine attachment site 938 998 6.1E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00560 b85d32e6473719ccd894a65072758345 2512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1636 1647 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 SUPERFAMILY SSF143800 1 67 3.73E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 Pfam PF01197 Ribosomal protein L31 1 66 2.0E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 6.8E-33 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 PRINTS PR01249 Ribosomal protein L31 signature 32 47 5.8E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 PRINTS PR01249 Ribosomal protein L31 signature 47 65 5.8E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.8E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS07115 057445ebfd947f65a289a37af9d8f37a 80 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.877 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Gene3D G3DSA:1.20.1560.10 2 323 5.9E-56 T 28-03-2018 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Gene3D G3DSA:1.20.1560.10 593 928 3.3E-49 T 28-03-2018 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Pfam PF00005 ABC transporter 350 499 1.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Pfam PF00005 ABC transporter 960 1107 1.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SUPERFAMILY SSF52540 327 566 8.84E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SMART SM00382 359 553 2.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SMART SM00382 968 1154 3.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Pfam PF00664 ABC transporter transmembrane region 20 285 6.0E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Pfam PF00664 ABC transporter transmembrane region 628 897 1.7E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SUPERFAMILY SSF90123 8 325 4.71E-64 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SUPERFAMILY SSF90123 613 923 7.06E-60 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 SUPERFAMILY SSF52540 934 1177 3.73E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Gene3D G3DSA:3.40.50.300 324 571 9.6E-65 T 28-03-2018 CP478_RS01060 6973c3819b13850a615e76f70c3051d2 1194 Gene3D G3DSA:3.40.50.300 933 1182 1.2E-66 T 28-03-2018 CP478_RS13630 d1391c7b22a33bab5abd1753579ea68d 250 SUPERFAMILY SSF55831 18 237 4.06E-27 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS13630 d1391c7b22a33bab5abd1753579ea68d 250 Gene3D G3DSA:3.30.572.10 60 248 4.6E-11 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 Gene3D G3DSA:2.70.70.10 244 375 5.4E-22 T 28-03-2018 CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 Gene3D G3DSA:3.90.550.10 4 243 7.2E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 SUPERFAMILY SSF51261 262 373 6.8E-20 T 28-03-2018 IPR011055 Duplicated hybrid motif CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 SUPERFAMILY SSF53448 7 198 2.63E-11 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 Pfam PF01551 Peptidase family M23 275 369 1.6E-15 T 28-03-2018 IPR016047 Peptidase M23 CP478_RS20685 4bb0b71f54a9694e27bd06b1f5b5653c 407 Pfam PF13704 Glycosyl transferase family 2 11 105 3.3E-9 T 28-03-2018 CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 SUPERFAMILY SSF46548 375 420 5.49E-20 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 SUPERFAMILY SSF46548 279 326 5.49E-20 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 392 403 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 Gene3D G3DSA:1.10.1060.10 260 429 6.4E-32 T 28-03-2018 CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 Gene3D G3DSA:1.20.950.20 3 246 5.2E-35 T 28-03-2018 CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 Pfam PF13183 4Fe-4S dicluster domain 292 406 4.5E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 Pfam PF02754 Cysteine-rich domain 607 693 5.6E-18 T 28-03-2018 IPR004017 Cysteine-rich domain CP478_RS01810 ab5b4b9c88c32d7a8412ec45565a3d24 882 Pfam PF02754 Cysteine-rich domain 477 568 7.9E-18 T 28-03-2018 IPR004017 Cysteine-rich domain CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 SMART SM00740 697 762 1.0E-12 T 28-03-2018 IPR005543 PASTA domain CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 Gene3D G3DSA:3.40.710.10 287 738 3.8E-69 T 28-03-2018 CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 Pfam PF03793 PASTA domain 702 761 2.5E-9 T 28-03-2018 IPR005543 PASTA domain CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 SUPERFAMILY SSF56601 295 691 1.51E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 SUPERFAMILY SSF56601 238 260 1.51E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 Pfam PF00912 Transglycosylase 70 256 1.3E-53 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 Gene3D G3DSA:1.10.3810.10 62 273 1.6E-63 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 Pfam PF00905 Penicillin binding protein transpeptidase domain 364 620 3.3E-20 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CP478_RS20105 2dec606b17d6be198b033aa03454a781 810 SUPERFAMILY SSF53955 59 284 1.6E-59 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 SUPERFAMILY SSF52402 10 139 6.03E-20 T 28-03-2018 CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 Pfam PF00582 Universal stress protein family 8 137 3.1E-20 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 Gene3D G3DSA:3.40.50.620 142 253 0.008 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 Gene3D G3DSA:3.40.50.620 1 137 1.4E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 PRINTS PR01438 Universal stress protein signature 7 25 2.1E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 PRINTS PR01438 Universal stress protein signature 115 137 2.1E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS17155 58948f0d7f2576e43e4fb7ea70b74b56 268 PRINTS PR01438 Universal stress protein signature 98 110 2.1E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 SUPERFAMILY SSF48498 85 192 6.3E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 SUPERFAMILY SSF46689 11 75 1.54E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 Gene3D G3DSA:1.10.10.60 1 67 2.6E-13 T 28-03-2018 CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 9.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 Gene3D G3DSA:1.10.357.10 68 201 1.1E-19 T 28-03-2018 CP478_RS06410 94eeeea83da7ad44fda7d75616685fe3 201 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 190 2.4E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01885 2b407ee1ee17c69355cbbecf7c0b7e49 126 Gene3D G3DSA:1.10.1660.10 2 116 3.7E-25 T 28-03-2018 CP478_RS01885 2b407ee1ee17c69355cbbecf7c0b7e49 126 SMART SM00422 13 82 4.8E-27 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS01885 2b407ee1ee17c69355cbbecf7c0b7e49 126 SUPERFAMILY SSF46955 14 103 1.51E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS01885 2b407ee1ee17c69355cbbecf7c0b7e49 126 Pfam PF13411 MerR HTH family regulatory protein 15 80 5.3E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS07660 5d1aded11ff833bc41e32725e97a4f62 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 40 2.0E-10 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS07660 5d1aded11ff833bc41e32725e97a4f62 85 Gene3D G3DSA:1.10.1220.10 1 79 3.8E-13 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS07660 5d1aded11ff833bc41e32725e97a4f62 85 SUPERFAMILY SSF47598 1 38 7.04E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS11755 f39922157511da519f24d369d8c7650e 288 Pfam PF00296 Luciferase-like monooxygenase 19 248 3.1E-41 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS11755 f39922157511da519f24d369d8c7650e 288 SUPERFAMILY SSF51679 19 272 1.62E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS11755 f39922157511da519f24d369d8c7650e 288 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 19 254 4.4E-65 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CP478_RS11755 f39922157511da519f24d369d8c7650e 288 Gene3D G3DSA:3.20.20.30 18 283 8.7E-52 T 28-03-2018 CP478_RS16710 da97a16584d0033566dad5aae52893da 184 Pfam PF03358 NADPH-dependent FMN reductase 9 155 7.2E-34 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CP478_RS16710 da97a16584d0033566dad5aae52893da 184 Gene3D G3DSA:3.40.50.360 2 184 3.6E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS16710 da97a16584d0033566dad5aae52893da 184 SUPERFAMILY SSF52218 9 157 2.1E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 Hamap MF_01227 CTP synthase [pyrG]. 9 549 48.503 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 Pfam PF06418 CTP synthase N-terminus 10 278 7.9E-120 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 Gene3D G3DSA:3.40.50.880 298 552 4.7E-66 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 Pfam PF00117 Glutamine amidotransferase class-I 313 542 5.1E-44 T 28-03-2018 IPR017926 Glutamine amidotransferase CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 TIGRFAM TIGR00337 PyrG: CTP synthase 9 544 2.0E-222 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 Gene3D G3DSA:3.40.50.300 1 297 2.0E-126 T 28-03-2018 CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 SUPERFAMILY SSF52317 301 549 3.64E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS09270 404a9e01e36e0c8f8430f3977c3dfdd0 586 SUPERFAMILY SSF52540 9 278 3.52E-116 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13135 dae703f35495ffbb4c7791770ab1adc1 273 SMART SM00849 19 211 4.5E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS13135 dae703f35495ffbb4c7791770ab1adc1 273 Hamap MF_01818 Ribonuclease BN [rbn]. 2 269 21.204 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CP478_RS13135 dae703f35495ffbb4c7791770ab1adc1 273 SUPERFAMILY SSF56281 3 268 2.71E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS13135 dae703f35495ffbb4c7791770ab1adc1 273 Gene3D G3DSA:3.60.15.10 2 273 2.2E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS13135 dae703f35495ffbb4c7791770ab1adc1 273 Pfam PF12706 Beta-lactamase superfamily domain 32 234 1.2E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 Gene3D G3DSA:3.40.640.10 27 263 1.2E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 Gene3D G3DSA:3.90.1150.10 264 376 1.7E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 SUPERFAMILY SSF53383 22 375 1.52E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 Pfam PF00266 Aminotransferase class-V 41 335 3.7E-16 T 28-03-2018 IPR000192 Aminotransferase class V domain CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 PIRSF PIRSF000525 6 376 3.3E-85 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 16 376 7.4E-224 T 28-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CP478_RS04820 ffbbf232a3e96f3228eb1ff77cdadc08 376 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 10 376 24.57 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CP478_RS11860 b0706848133d8a4b475a8d2503459aaf 427 Pfam PF09594 Glycosyltransferase family 87 80 324 1.8E-60 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 SUPERFAMILY SSF53738 206 319 2.75E-14 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 442 1.7E-27 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Gene3D G3DSA:3.30.310.50 446 547 2.8E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Gene3D G3DSA:3.40.120.10 329 441 3.2E-26 T 28-03-2018 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 SUPERFAMILY SSF53738 25 233 1.71E-47 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Gene3D G3DSA:3.40.120.10 28 215 1.1E-43 T 28-03-2018 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 SUPERFAMILY SSF55957 435 547 2.09E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 493 540 1.3E-6 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 209 318 8.5E-11 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 181 7.2E-38 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 547 0.0 T 28-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 SUPERFAMILY SSF53738 308 450 2.67E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS16790 995f04544d6c934ff9ddac7bca3fedeb 547 Gene3D G3DSA:3.40.120.10 216 328 2.6E-20 T 28-03-2018 CP478_RS06260 b43c0706039eccbe1f0032e46d4147a0 360 SUPERFAMILY SSF89796 3 359 4.97E-112 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS06260 b43c0706039eccbe1f0032e46d4147a0 360 Pfam PF02515 CoA-transferase family III 5 343 3.5E-80 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CP478_RS06260 b43c0706039eccbe1f0032e46d4147a0 360 Gene3D G3DSA:3.40.50.10540 1 359 1.6E-108 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 454 3.8E-28 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 SUPERFAMILY SSF55424 342 456 1.19E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 308 3.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 Gene3D G3DSA:3.30.390.30 334 459 1.5E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 Gene3D G3DSA:3.40.50.720 165 330 3.2E-29 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PIRSF PIRSF000350 1 443 6.9E-76 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 SUPERFAMILY SSF51905 1 375 6.02E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 3 458 7.0E-245 T 28-03-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 Gene3D G3DSA:3.50.50.60 1 164 2.3E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 1.8E-22 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 1.8E-22 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 1.8E-22 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-22 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.8E-22 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-40 T 28-03-2018 CP478_RS15605 f0c33e728bf0f17835e8fea49e84a19e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 1.6E-40 T 28-03-2018 CP478_RS07780 db160cac1ae389afdeec886c6da7057b 342 Pfam PF01933 Uncharacterised protein family UPF0052 5 281 2.7E-70 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CP478_RS07780 db160cac1ae389afdeec886c6da7057b 342 Gene3D G3DSA:3.40.50.10680 84 314 6.3E-51 T 28-03-2018 CP478_RS07780 db160cac1ae389afdeec886c6da7057b 342 Hamap MF_00973 Gluconeogenesis factor. 1 313 32.073 T 28-03-2018 IPR010119 Gluconeogenesis factor CP478_RS07780 db160cac1ae389afdeec886c6da7057b 342 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 5 311 1.9E-105 T 28-03-2018 IPR010119 Gluconeogenesis factor CP478_RS07780 db160cac1ae389afdeec886c6da7057b 342 SUPERFAMILY SSF142338 4 307 7.46E-84 T 28-03-2018 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 SMART SM00382 55 186 3.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 63 82 9.6E-6 T 28-03-2018 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 318 334 9.6E-6 T 28-03-2018 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 344 162.474 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 257 330 3.2E-29 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Gene3D G3DSA:3.40.50.300 22 185 1.6E-24 T 28-03-2018 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Gene3D G3DSA:1.10.8.60 188 258 3.0E-30 T 28-03-2018 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 11 239 4.9E-106 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 Gene3D G3DSA:1.10.10.10 261 331 4.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 331 8.5E-141 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 SUPERFAMILY SSF52540 24 255 3.6E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 257 332 4.0E-27 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CP478_RS14205 05e045e6cbf27583500c41762bfc3921 344 SUPERFAMILY SSF46785 260 334 1.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15835 beee3da10daca3138eb44747f704f9c6 128 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 10 112 4.4E-24 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CP478_RS15835 beee3da10daca3138eb44747f704f9c6 128 Hamap MF_00048 UPF0102 protein YraN [yraN]. 9 121 23.186 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CP478_RS15835 beee3da10daca3138eb44747f704f9c6 128 Pfam PF02021 Uncharacterised protein family UPF0102 16 108 2.0E-28 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CP478_RS15835 beee3da10daca3138eb44747f704f9c6 128 Gene3D G3DSA:3.40.1350.10 15 127 7.1E-33 T 28-03-2018 CP478_RS15835 beee3da10daca3138eb44747f704f9c6 128 SUPERFAMILY SSF52980 16 112 8.58E-19 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 192 25.658 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 191 1.2E-58 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 Gene3D G3DSA:3.40.50.620 1 193 1.5E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 61 9.3E-13 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 Pfam PF01467 Cytidylyltransferase-like 2 166 1.3E-31 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CP478_RS13215 9c8b8d2e8ea8dd46b1113ceb444f1198 211 SUPERFAMILY SSF52374 2 191 5.32E-48 T 28-03-2018 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Gene3D G3DSA:2.10.230.10 145 195 6.6E-12 T 28-03-2018 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SMART SM00271 3 60 1.1E-30 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Gene3D G3DSA:2.60.260.20 196 254 1.3E-14 T 28-03-2018 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SUPERFAMILY SSF49493 188 268 8.24E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SUPERFAMILY SSF49493 112 136 8.24E-17 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Pfam PF00226 DnaJ domain 4 65 1.3E-24 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SUPERFAMILY SSF46565 3 102 1.57E-32 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 378 36.52 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Gene3D G3DSA:2.60.260.20 256 368 3.4E-28 T 28-03-2018 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Pfam PF00684 DnaJ central domain 145 209 2.9E-12 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SUPERFAMILY SSF49493 260 347 2.09E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Pfam PF01556 DnaJ C terminal domain 121 336 4.6E-37 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 SUPERFAMILY SSF57938 132 212 2.62E-17 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 Gene3D G3DSA:1.10.287.110 1 107 1.7E-30 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 PRINTS PR00625 DnaJ domain signature 24 39 1.5E-22 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 PRINTS PR00625 DnaJ domain signature 60 79 1.5E-22 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 PRINTS PR00625 DnaJ domain signature 6 24 1.5E-22 T 28-03-2018 IPR001623 DnaJ domain CP478_RS12940 201281d0463f987f9e6ab64f3c1432ad 382 PRINTS PR00625 DnaJ domain signature 40 60 1.5E-22 T 28-03-2018 IPR001623 DnaJ domain CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 Gene3D G3DSA:3.30.420.40 98 272 4.5E-52 T 28-03-2018 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 Pfam PF03309 Type III pantothenate kinase 2 206 2.7E-55 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 257 5.5E-94 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 SUPERFAMILY SSF53067 2 123 1.39E-23 T 28-03-2018 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 SUPERFAMILY SSF53067 126 260 2.89E-30 T 28-03-2018 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 Gene3D G3DSA:3.30.420.40 1 97 8.9E-4 T 28-03-2018 CP478_RS19660 3101e04bd10205cfde6a9bed22714ae3 272 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 261 31.258 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Gene3D G3DSA:2.40.30.10 291 404 2.9E-29 T 28-03-2018 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SMART SM00838 607 694 6.3E-58 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SUPERFAMILY SSF54980 610 696 4.8E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SUPERFAMILY SSF50447 268 408 1.41E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SMART SM00889 484 605 1.3E-66 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 698 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Pfam PF03144 Elongation factor Tu domain 2 328 394 1.0E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 183 6.3E-35 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SUPERFAMILY SSF54211 483 606 2.15E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Gene3D G3DSA:3.30.70.240 621 698 6.4E-32 T 28-03-2018 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Pfam PF03764 Elongation factor G, domain IV 483 604 3.4E-45 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Gene3D G3DSA:3.30.70.870 405 497 7.0E-38 T 28-03-2018 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 PRINTS PR00315 GTP-binding elongation factor signature 97 108 1.0E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 PRINTS PR00315 GTP-binding elongation factor signature 133 142 1.0E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 PRINTS PR00315 GTP-binding elongation factor signature 81 91 1.0E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.0E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 PRINTS PR00315 GTP-binding elongation factor signature 61 69 1.0E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Gene3D G3DSA:3.40.50.300 8 290 3.4E-57 T 28-03-2018 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Pfam PF00009 Elongation factor Tu GTP binding domain 12 285 9.6E-68 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SUPERFAMILY SSF52540 9 285 1.23E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Gene3D G3DSA:3.30.230.10 498 620 3.2E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Pfam PF00679 Elongation factor G C-terminus 607 693 4.2E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Hamap MF_00054_B Elongation factor G [fusA]. 9 698 108.418 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 Pfam PF14492 Elongation Factor G, domain II 408 482 1.4E-33 T 28-03-2018 CP478_RS03695 e75211547b28819242d50058fab48dd1 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CP478_RS03695 e75211547b28819242d50058fab48dd1 701 SUPERFAMILY SSF54980 406 484 9.35E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS09730 140870eae0fcb5fb4aa0b465e1615875 365 SUPERFAMILY SSF140459 2 174 5.49E-64 T 28-03-2018 CP478_RS09730 140870eae0fcb5fb4aa0b465e1615875 365 Pfam PF00823 PPE family 5 161 6.6E-62 T 28-03-2018 IPR000030 PPE family CP478_RS09730 140870eae0fcb5fb4aa0b465e1615875 365 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 282 361 2.2E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS17135 8596e2fa59c3bb3b2bd49985998f0b31 463 SUPERFAMILY SSF52777 38 153 6.11E-9 T 28-03-2018 CP478_RS17135 8596e2fa59c3bb3b2bd49985998f0b31 463 Pfam PF06974 Protein of unknown function (DUF1298) 299 443 3.9E-28 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS17135 8596e2fa59c3bb3b2bd49985998f0b31 463 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 445 1.2E-146 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS17135 8596e2fa59c3bb3b2bd49985998f0b31 463 Gene3D G3DSA:3.30.559.10 3 171 2.6E-5 T 28-03-2018 CP478_RS17135 8596e2fa59c3bb3b2bd49985998f0b31 463 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 256 5.0E-79 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS09615 f436c9052b0821a767e5741e6e044b85 79 Pfam PF00665 Integrase core domain 4 79 5.1E-11 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS09615 f436c9052b0821a767e5741e6e044b85 79 SUPERFAMILY SSF53098 4 79 1.01E-13 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS09615 f436c9052b0821a767e5741e6e044b85 79 Gene3D G3DSA:3.30.420.10 1 79 1.7E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS18855 0a108696c3be998fce3a250a5d0f1d89 125 SUPERFAMILY SSF140453 26 118 2.09E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS18855 0a108696c3be998fce3a250a5d0f1d89 125 Pfam PF06013 Proteins of 100 residues with WXG 27 111 1.5E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS18855 0a108696c3be998fce3a250a5d0f1d89 125 Gene3D G3DSA:1.10.287.1060 23 120 5.2E-13 T 28-03-2018 CP478_RS09815 2d4c72ea9cf738a3de7b188067e66051 463 Gene3D G3DSA:1.10.287.1060 22 104 1.8E-7 T 28-03-2018 CP478_RS09815 2d4c72ea9cf738a3de7b188067e66051 463 Pfam PF00823 PPE family 5 160 2.8E-63 T 28-03-2018 IPR000030 PPE family CP478_RS09815 2d4c72ea9cf738a3de7b188067e66051 463 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 308 379 4.5E-11 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09815 2d4c72ea9cf738a3de7b188067e66051 463 SUPERFAMILY SSF140459 2 173 1.6E-65 T 28-03-2018 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Gene3D G3DSA:3.30.930.10 26 258 3.7E-54 T 28-03-2018 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Gene3D G3DSA:3.30.930.10 400 470 3.4E-8 T 28-03-2018 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 7.5E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 7.5E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 7.5E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 7.5E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.235 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 SUPERFAMILY SSF52954 476 564 9.32E-22 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Gene3D G3DSA:3.40.50.800 471 579 3.3E-25 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 566 3.7E-163 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 471 5.2E-38 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Gene3D G3DSA:3.90.960.10 259 399 1.9E-33 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Pfam PF03129 Anticodon binding domain 491 565 2.3E-12 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 SUPERFAMILY SSF55826 221 392 6.02E-11 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 Pfam PF04073 Aminoacyl-tRNA editing domain 261 391 1.3E-20 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 SUPERFAMILY SSF55681 419 489 5.36E-86 T 28-03-2018 CP478_RS15555 c1d104fbbe83ee9655da8816c25ef5be 582 SUPERFAMILY SSF55681 12 239 5.36E-86 T 28-03-2018 CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 SUPERFAMILY SSF46785 37 103 3.23E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 Gene3D G3DSA:3.30.420.40 107 246 1.7E-22 T 28-03-2018 CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 Gene3D G3DSA:3.30.420.40 247 393 4.1E-17 T 28-03-2018 CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 SUPERFAMILY SSF53067 109 406 1.06E-26 T 28-03-2018 CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 Pfam PF00480 ROK family 110 378 1.1E-17 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CP478_RS02585 32c2fc1ce0935fc82473396cca7bd87e 438 Gene3D G3DSA:1.10.10.10 32 104 7.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00565 750427edbb4b428cce1e90f72cd120b2 661 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 381 625 5.3E-80 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CP478_RS00565 750427edbb4b428cce1e90f72cd120b2 661 Pfam PF05425 Copper resistance protein D 117 234 1.6E-12 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 ProSitePatterns PS01229 Hypothetical cof family signature 2. 542 564 - T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00941 Cadmium-transporting ATPase signature 122 142 8.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00941 Cadmium-transporting ATPase signature 51 68 8.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00941 Cadmium-transporting ATPase signature 204 220 8.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00941 Cadmium-transporting ATPase signature 68 80 8.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00941 Cadmium-transporting ATPase signature 223 237 8.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF81660 356 476 1.5E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 Gene3D G3DSA:2.70.150.10 20 239 1.1E-27 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 111 608 3.4E-67 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 499 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 477 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 578 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 188 202 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 561 3.8E-23 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF56784 438 642 2.31E-47 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF56784 337 356 2.31E-47 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 87 645 4.5E-165 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 Gene3D G3DSA:3.40.1110.10 355 467 4.4E-29 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF81653 145 238 4.58E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 Pfam PF00122 E1-E2 ATPase 138 317 6.1E-47 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 555 6.3E-39 T 28-03-2018 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 Gene3D G3DSA:3.40.50.1000 468 608 1.6E-32 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF81665 89 141 1.57E-7 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF81665 239 332 1.57E-7 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS20440 0155cae4488e8b7793c24529de3ecbb5 660 SUPERFAMILY SSF81665 595 626 1.57E-7 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS02640 b28186936df97d74a56af524358cc204 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 3.1E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS02640 b28186936df97d74a56af524358cc204 242 SMART SM00895 108 229 1.4E-9 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS02640 b28186936df97d74a56af524358cc204 242 SUPERFAMILY SSF48008 104 236 1.28E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS02640 b28186936df97d74a56af524358cc204 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 2.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS02640 b28186936df97d74a56af524358cc204 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 2.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS02640 b28186936df97d74a56af524358cc204 242 Pfam PF07729 FCD domain 108 228 1.8E-13 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS02640 b28186936df97d74a56af524358cc204 242 SMART SM00345 23 82 4.3E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS02640 b28186936df97d74a56af524358cc204 242 SUPERFAMILY SSF46785 12 86 3.37E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02640 b28186936df97d74a56af524358cc204 242 Gene3D G3DSA:1.10.10.10 3 84 4.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02640 b28186936df97d74a56af524358cc204 242 Gene3D G3DSA:1.20.120.530 102 242 4.9E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS18690 02848acd7505e88ae9eb26e30386d12f 275 Gene3D G3DSA:1.25.40.10 144 262 0.0013 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS18690 02848acd7505e88ae9eb26e30386d12f 275 Gene3D G3DSA:1.25.40.10 16 138 2.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Gene3D G3DSA:3.30.300.30 456 570 6.9E-30 T 28-03-2018 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Gene3D G3DSA:3.40.50.980 50 220 1.2E-21 T 28-03-2018 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 SUPERFAMILY SSF56801 52 565 3.01E-127 T 28-03-2018 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Pfam PF00501 AMP-binding enzyme 59 461 1.3E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Gene3D G3DSA:3.40.50.980 221 371 1.0E-38 T 28-03-2018 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Gene3D G3DSA:2.30.38.10 372 454 8.1E-27 T 28-03-2018 CP478_RS02950 f5d42a116c098acde9f1715c29540b59 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 552 1.0E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS15970 e1d22b5ad1c579d477e1dfae59795abb 137 Gene3D G3DSA:3.30.300.20 2 136 1.3E-19 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS15970 e1d22b5ad1c579d477e1dfae59795abb 137 Pfam PF02566 OsmC-like protein 34 130 3.2E-9 T 28-03-2018 IPR003718 OsmC/Ohr family CP478_RS15970 e1d22b5ad1c579d477e1dfae59795abb 137 SUPERFAMILY SSF82784 3 133 5.23E-20 T 28-03-2018 IPR003718 OsmC/Ohr family CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 SUPERFAMILY SSF48498 84 192 9.54E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 SUPERFAMILY SSF46689 5 87 3.85E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 Gene3D G3DSA:1.10.10.60 4 64 1.7E-18 T 28-03-2018 CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 9.1E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 Gene3D G3DSA:1.10.357.10 65 197 1.0E-23 T 28-03-2018 CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01290 a97dc6dfb7b0ea470a113b971cd52973 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04300 3cfea3dfc58fbb59d4cd71c12e695d19 347 Pfam PF00296 Luciferase-like monooxygenase 23 277 2.1E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS04300 3cfea3dfc58fbb59d4cd71c12e695d19 347 SUPERFAMILY SSF51679 86 341 7.71E-76 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS04300 3cfea3dfc58fbb59d4cd71c12e695d19 347 SUPERFAMILY SSF51679 8 58 7.71E-76 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS04300 3cfea3dfc58fbb59d4cd71c12e695d19 347 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 31 319 4.0E-54 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CP478_RS04300 3cfea3dfc58fbb59d4cd71c12e695d19 347 Gene3D G3DSA:3.20.20.30 1 343 2.7E-78 T 28-03-2018 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 PIRSF PIRSF000429 1 403 2.0E-109 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 401 6.8E-130 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 SUPERFAMILY SSF53901 281 402 5.76E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 SUPERFAMILY SSF53901 2 274 6.43E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 Pfam PF00108 Thiolase, N-terminal domain 6 226 2.0E-46 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 Gene3D G3DSA:3.40.47.10 279 403 2.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 3.7E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS04690 010fe76060076e26acec39b453b1a982 403 Gene3D G3DSA:3.40.47.10 1 278 5.6E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16845 77be12ba7c1d13f69ae7f67402b48d4b 275 Gene3D G3DSA:3.20.20.30 16 236 2.1E-50 T 28-03-2018 CP478_RS16845 77be12ba7c1d13f69ae7f67402b48d4b 275 SUPERFAMILY SSF51679 17 267 3.93E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16845 77be12ba7c1d13f69ae7f67402b48d4b 275 Pfam PF00296 Luciferase-like monooxygenase 18 218 3.8E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16845 77be12ba7c1d13f69ae7f67402b48d4b 275 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 251 6.1E-78 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 6 408 6.3E-206 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 274 293 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 Gene3D G3DSA:3.40.718.10 4 409 4.5E-133 T 28-03-2018 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 SMART SM01329 12 399 3.4E-135 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 PIRSF PIRSF000108 1 409 3.6E-223 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 SUPERFAMILY SSF53659 5 407 2.11E-152 T 28-03-2018 CP478_RS18285 c0ba20cc0aff3154e4f841b71d252df1 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 12 399 4.5E-73 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 292 302 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 SUPERFAMILY SSF64153 3 231 4.45E-47 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 200 19.51 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Gene3D G3DSA:3.40.50.10260 2 213 6.1E-51 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 SUPERFAMILY SSF53613 213 470 3.27E-59 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 471 20.295 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 PIRSF PIRSF017184 1 472 4.4E-93 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Pfam PF01256 Carbohydrate kinase 234 462 3.8E-73 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Pfam PF03853 YjeF-related protein N-terminus 25 182 1.4E-35 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 Gene3D G3DSA:3.40.1190.20 214 473 1.1E-45 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 226 448 5.7E-42 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 408 418 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CP478_RS18795 c95d4df9100f57f95dce6e9f6de70cad 473 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 21 200 1.9E-28 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CP478_RS08925 502a0cee0388637add42d4edb7682da0 147 Pfam PF04167 Protein of unknown function (DUF402) 28 95 1.5E-15 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CP478_RS08925 502a0cee0388637add42d4edb7682da0 147 PIRSF PIRSF012622 1 147 1.7E-80 T 28-03-2018 IPR014465 Uncharacterised conserved protein UCP012622 CP478_RS08925 502a0cee0388637add42d4edb7682da0 147 Gene3D G3DSA:2.40.380.10 1 140 8.1E-44 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CP478_RS08925 502a0cee0388637add42d4edb7682da0 147 SUPERFAMILY SSF159234 1 144 1.96E-45 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CP478_RS21205 b9ca396a2b6507f11565128d4807e867 729 SUPERFAMILY SSF140453 21 114 5.1E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS08070 ef77ec719f8707021743391f19a57827 542 SMART SM00382 28 242 1.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS08070 ef77ec719f8707021743391f19a57827 542 SMART SM00382 360 526 3.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS08070 ef77ec719f8707021743391f19a57827 542 SUPERFAMILY SSF52540 5 239 1.57E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08070 ef77ec719f8707021743391f19a57827 542 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 Gene3D G3DSA:3.40.50.300 303 541 2.7E-49 T 28-03-2018 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 Pfam PF00005 ABC transporter 353 481 5.4E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 Pfam PF00005 ABC transporter 23 197 5.0E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 Gene3D G3DSA:3.40.50.300 1 302 1.2E-43 T 28-03-2018 CP478_RS08070 ef77ec719f8707021743391f19a57827 542 Pfam PF12848 ABC transporter 242 314 4.3E-8 T 28-03-2018 IPR032781 ABC-transporter extension domain CP478_RS08070 ef77ec719f8707021743391f19a57827 542 SUPERFAMILY SSF52540 341 525 1.63E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02325 205dd72b614d1e825289dd1c66ec5cf0 231 Gene3D G3DSA:2.40.50.100 112 229 0.33 T 28-03-2018 CP478_RS02325 205dd72b614d1e825289dd1c66ec5cf0 231 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 30 229 7.1E-46 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CP478_RS02325 205dd72b614d1e825289dd1c66ec5cf0 231 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 23 231 35.057 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CP478_RS02325 205dd72b614d1e825289dd1c66ec5cf0 231 Pfam PF02666 Phosphatidylserine decarboxylase 59 227 7.0E-32 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CP478_RS19780 8469f253056a3aa72770c9af3ec25eae 99 Pfam PF00934 PE family 1 93 6.1E-27 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19780 8469f253056a3aa72770c9af3ec25eae 99 SUPERFAMILY SSF140459 8 84 1.28E-20 T 28-03-2018 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Gene3D G3DSA:1.20.120.430 333 452 5.2E-12 T 28-03-2018 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Hamap MF_00900 GTPase HflX [hflX]. 92 465 47.648 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 PIRSF PIRSF006809 64 494 8.4E-172 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Gene3D G3DSA:3.40.50.300 81 332 7.2E-16 T 28-03-2018 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 73 435 4.9E-131 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Pfam PF13167 GTP-binding GTPase N-terminal 90 177 9.5E-33 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Pfam PF16360 GTP-binding GTPase Middle Region 179 265 3.6E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 340 358 5.7E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 273 293 5.7E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 SUPERFAMILY SSF52540 272 460 6.04E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14930 ebf25958b0b4f30aface6441585ac3e9 495 Pfam PF01926 50S ribosome-binding GTPase 273 395 1.3E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS13775 420d7b8c681d5e18adfcd24e618bea20 267 Gene3D G3DSA:1.10.10.10 73 109 7.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13775 420d7b8c681d5e18adfcd24e618bea20 267 Gene3D G3DSA:1.10.10.10 110 156 4.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05885 a3f95c9ecf76a8316d1ceac3ef60cd51 283 Gene3D G3DSA:3.40.960.10 178 283 1.0E-9 T 28-03-2018 CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 SMART SM00100 378 493 1.3E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 SUPERFAMILY SSF51735 196 290 1.66E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 Pfam PF00027 Cyclic nucleotide-binding domain 397 475 2.9E-17 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 SUPERFAMILY SSF52283 16 184 8.67E-8 T 28-03-2018 CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 Gene3D G3DSA:3.40.50.720 23 310 1.5E-9 T 28-03-2018 CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 SUPERFAMILY SSF51206 379 487 4.84E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS00575 f7e8c7cd21d3c6551b4ef6bd4026d658 504 Gene3D G3DSA:2.60.120.10 379 498 6.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS16170 1cd96cfe308f3cf92222780811b86dd7 245 Pfam PF04989 Cephalosporin hydroxylase 50 244 3.6E-72 T 28-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 CP478_RS16170 1cd96cfe308f3cf92222780811b86dd7 245 Gene3D G3DSA:3.40.50.150 64 232 3.9E-6 T 28-03-2018 CP478_RS16170 1cd96cfe308f3cf92222780811b86dd7 245 SUPERFAMILY SSF53335 33 244 1.87E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.0E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 2.0E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.0E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.0E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.0E-52 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 155 2.1E-60 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 Gene3D G3DSA:3.40.50.620 1 157 1.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 76 0.002 T 28-03-2018 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.014 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 8.0E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 Pfam PF01467 Cytidylyltransferase-like 6 131 5.4E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CP478_RS16210 66b61500ff1d341abc41e827e3fadf6a 161 SUPERFAMILY SSF52374 1 154 3.84E-44 T 28-03-2018 CP478_RS16155 9b2ec9edd6c0fd5672ca3d8e26b5a97b 275 Pfam PF00535 Glycosyl transferase family 2 26 148 1.2E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS16155 9b2ec9edd6c0fd5672ca3d8e26b5a97b 275 SUPERFAMILY SSF53448 23 219 8.44E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS16155 9b2ec9edd6c0fd5672ca3d8e26b5a97b 275 Gene3D G3DSA:3.90.550.10 4 261 3.9E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS04685 d163a3e7d6bb9b8da0d7de0c48837757 397 SUPERFAMILY SSF53383 4 389 1.02E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS04685 d163a3e7d6bb9b8da0d7de0c48837757 397 Pfam PF00155 Aminotransferase class I and II 27 388 5.4E-61 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS04685 d163a3e7d6bb9b8da0d7de0c48837757 397 Gene3D G3DSA:3.40.640.10 40 291 1.0E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS04685 d163a3e7d6bb9b8da0d7de0c48837757 397 Gene3D G3DSA:3.90.1150.10 292 395 5.0E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS09015 4622c516f6ff24adaefcb47ec1e3f4c6 316 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 127 265 1.1E-11 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS09015 4622c516f6ff24adaefcb47ec1e3f4c6 316 SUPERFAMILY SSF55073 124 272 7.69E-36 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS09015 4622c516f6ff24adaefcb47ec1e3f4c6 316 Gene3D G3DSA:3.30.70.1230 119 310 2.8E-27 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS09015 4622c516f6ff24adaefcb47ec1e3f4c6 316 SMART SM00044 82 284 2.2E-36 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 SUPERFAMILY SSF56645 5 253 4.58E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Gene3D G3DSA:2.40.110.10 128 229 7.8E-34 T 28-03-2018 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Gene3D G3DSA:1.20.140.10 230 403 7.2E-50 T 28-03-2018 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 390 9.8E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 227 1.2E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 5.7E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 SUPERFAMILY SSF47203 238 395 5.32E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS00840 4bf243e36138577a0de60abb77eb7c93 403 Gene3D G3DSA:1.10.540.10 1 127 4.6E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF51735 1761 1991 1.82E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1446 1512 8.3E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.90.180.10 1656 1738 7.3E-5 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF51735 1186 1403 2.09E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.50.720 1739 1981 1.2E-41 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 376 9.6E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.366.10 523 714 1.1E-41 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.366.10 715 835 4.7E-22 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF52151 534 659 1.88E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF52151 724 822 1.88E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:1.10.1200.10 2023 2111 1.5E-15 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.47.10 1 267 3.6E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1765 1944 6.4E-43 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 832 4.4E-91 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00825 Beta-ketoacyl synthase 8 431 5.5E-194 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF00550 Phosphopantetheine attachment site 2031 2096 1.2E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.47.10 270 429 2.5E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF47336 2023 2109 2.62E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 497 2.1E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.90.180.10 1408 1555 5.6E-34 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.40.50.720 1556 1655 1.9E-24 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2055 2070 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00823 Phosphopantetheine attachment site 2032 2100 4.3E-12 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF08659 KR domain 1765 1942 1.9E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF50129 1423 1560 6.29E-31 T 28-03-2018 IPR011032 GroES-like CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00826 896 1057 5.5E-38 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SMART SM00829 1429 1741 3.9E-159 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Gene3D G3DSA:3.10.129.10 896 1017 2.2E-7 T 28-03-2018 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF51735 1530 1687 5.19E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF14765 Polyketide synthase dehydratase 896 1175 4.1E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 168 184 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF00698 Acyl transferase domain 534 850 2.7E-114 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF55048 658 723 1.83E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF53901 6 372 9.56E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 SUPERFAMILY SSF53901 406 416 9.56E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF00107 Zinc-binding dehydrogenase 1570 1660 1.8E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS16060 dd7081000e34a01cbd4e3bb9ba01d9ad 2111 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 255 3.4E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 Gene3D G3DSA:3.30.420.10 21 225 2.6E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 SUPERFAMILY SSF53098 18 242 6.68E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 SMART SM00474 31 202 1.2E-33 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 SUPERFAMILY SSF47819 231 323 7.85E-22 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 Pfam PF01612 3'-5' exonuclease 43 201 2.4E-31 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 SMART SM00341 245 325 4.1E-25 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 Pfam PF00570 HRDC domain 249 314 4.3E-13 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CP478_RS14700 1a51b0ea0cfdc9f5a7d0618f1c240c86 438 Gene3D G3DSA:1.10.150.80 229 343 1.9E-27 T 28-03-2018 CP478_RS02035 0a4f8562ef99efd2e8dd4793ede6546f 179 SUPERFAMILY SSF53271 10 175 2.36E-34 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS02035 0a4f8562ef99efd2e8dd4793ede6546f 179 Gene3D G3DSA:3.40.50.2020 3 179 2.8E-33 T 28-03-2018 CP478_RS02035 0a4f8562ef99efd2e8dd4793ede6546f 179 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 19 175 1.4E-35 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS02035 0a4f8562ef99efd2e8dd4793ede6546f 179 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 179 25.355 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS02035 0a4f8562ef99efd2e8dd4793ede6546f 179 Pfam PF00156 Phosphoribosyl transferase domain 45 158 1.9E-11 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 1.5E-39 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 PRINTS PR00423 Cell division protein FtsZ signature 186 208 7.7E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 PRINTS PR00423 Cell division protein FtsZ signature 123 144 7.7E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 PRINTS PR00423 Cell division protein FtsZ signature 95 115 7.7E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 PRINTS PR00423 Cell division protein FtsZ signature 209 230 7.7E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 1.2E-125 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 SUPERFAMILY SSF55307 201 314 9.16E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 SMART SM00864 10 202 3.2E-107 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 327 38.103 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 Gene3D G3DSA:3.30.1330.20 212 318 3.0E-44 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 SUPERFAMILY SSF52490 9 205 1.23E-66 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 Gene3D G3DSA:3.40.50.1440 5 211 2.9E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 SMART SM00865 204 321 6.7E-54 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CP478_RS11700 5c94138ce690b155f86dd3e81cde21f8 379 Pfam PF12327 FtsZ family, C-terminal domain 219 313 6.5E-35 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CP478_RS01765 6e23090c25a2bec8b16256604a5fc8ff 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 5.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01765 6e23090c25a2bec8b16256604a5fc8ff 246 Gene3D G3DSA:1.10.260.40 35 101 1.7E-6 T 28-03-2018 CP478_RS01765 6e23090c25a2bec8b16256604a5fc8ff 246 Gene3D G3DSA:1.10.357.10 102 246 6.4E-9 T 28-03-2018 CP478_RS01765 6e23090c25a2bec8b16256604a5fc8ff 246 SUPERFAMILY SSF46689 6 66 2.15E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS01765 6e23090c25a2bec8b16256604a5fc8ff 246 Gene3D G3DSA:1.10.10.60 2 34 3.8E-8 T 28-03-2018 CP478_RS04580 5b590c45f7f3ba07c7a3e0b6ab28d0d4 270 SUPERFAMILY SSF53335 6 212 9.21E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS04580 5b590c45f7f3ba07c7a3e0b6ab28d0d4 270 Pfam PF13847 Methyltransferase domain 40 146 2.4E-27 T 28-03-2018 IPR025714 Methyltransferase domain CP478_RS04580 5b590c45f7f3ba07c7a3e0b6ab28d0d4 270 Gene3D G3DSA:3.40.50.150 3 260 6.3E-40 T 28-03-2018 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 359 366 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 SUPERFAMILY SSF52949 27 179 3.65E-23 T 28-03-2018 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 Gene3D G3DSA:3.40.630.10 177 515 5.7E-128 T 28-03-2018 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 13 513 34.436 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 Gene3D G3DSA:3.40.220.10 12 172 3.2E-28 T 28-03-2018 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 SUPERFAMILY SSF53187 188 511 4.71E-106 T 28-03-2018 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 193 504 9.9E-115 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 PRINTS PR00481 Cytosol aminopeptidase signature 355 375 1.1E-47 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 PRINTS PR00481 Cytosol aminopeptidase signature 333 354 1.1E-47 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 PRINTS PR00481 Cytosol aminopeptidase signature 274 291 1.1E-47 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 PRINTS PR00481 Cytosol aminopeptidase signature 296 317 1.1E-47 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 PRINTS PR00481 Cytosol aminopeptidase signature 383 398 1.1E-47 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CP478_RS12025 55431c144eee6b83bdbd77b991dda779 515 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 30 157 1.4E-26 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 312 9.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 Gene3D G3DSA:1.10.287.130 225 309 3.1E-16 T 28-03-2018 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SUPERFAMILY SSF55874 302 468 4.71E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SMART SM00304 181 234 1.0E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SUPERFAMILY SSF158472 181 231 1.7E-7 T 28-03-2018 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SUPERFAMILY SSF47384 238 313 5.3E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 4.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 4.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 4.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 4.1E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 468 6.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 Pfam PF00672 HAMP domain 181 231 1.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SMART SM00387 358 470 4.5E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 SMART SM00388 249 313 1.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04130 5cdd5288c844c681fa2acac34430e24f 485 Gene3D G3DSA:3.30.565.10 327 481 1.1E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17600 e4f95b2b18046bc4c405b3b306cb3fc5 231 Gene3D G3DSA:1.20.1260.10 21 231 4.1E-36 T 28-03-2018 IPR012347 Ferritin-related CP478_RS17600 e4f95b2b18046bc4c405b3b306cb3fc5 231 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 24 202 7.6E-59 T 28-03-2018 CP478_RS17600 e4f95b2b18046bc4c405b3b306cb3fc5 231 SUPERFAMILY SSF47240 19 137 3.76E-8 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS11180 6a2b5a70f8f2b35f37fcdbc70c98eb89 111 Pfam PF13397 RNA polymerase-binding protein 4 106 6.5E-40 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CP478_RS11180 6a2b5a70f8f2b35f37fcdbc70c98eb89 111 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 22.774 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 Gene3D G3DSA:1.20.1290.10 1 177 8.5E-46 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 177 79.109 T 28-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 2 177 1.7E-96 T 28-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 101 174 7.7E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 111 159 2.5E-20 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS13270 1dc85c872f2f50b56aedb1e82333ecf8 177 SUPERFAMILY SSF69118 3 174 5.04E-49 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 PIRSF PIRSF004848 8 258 1.0E-71 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 16 253 1.1E-32 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 Pfam PF01168 Alanine racemase, N-terminal domain 19 253 1.8E-14 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 SUPERFAMILY SSF51419 10 251 3.05E-57 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 Gene3D G3DSA:3.20.20.10 2 257 8.8E-53 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS11690 6140affa82229c638c9b89d93e63c283 258 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 97 111 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CP478_RS11885 df84349bb8667f28aa79d8cd3331a80f 129 Gene3D G3DSA:3.30.530.20 50 119 1.4E-4 T 28-03-2018 IPR023393 START-like domain CP478_RS11885 df84349bb8667f28aa79d8cd3331a80f 129 SUPERFAMILY SSF55961 5 93 9.7E-11 T 28-03-2018 CP478_RS11885 df84349bb8667f28aa79d8cd3331a80f 129 Gene3D G3DSA:3.30.530.20 2 49 1.4E-4 T 28-03-2018 IPR023393 START-like domain CP478_RS15725 ff2c778f33ad4ace4a14aca30db61df0 104 Pfam PF10939 Protein of unknown function (DUF2631) 18 85 5.4E-30 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CP478_RS15725 ff2c778f33ad4ace4a14aca30db61df0 104 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 17 104 1.0E-44 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CP478_RS08770 1e1ae2c760d67559276ef578b1a89779 245 Gene3D G3DSA:3.20.20.70 5 245 3.7E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08770 1e1ae2c760d67559276ef578b1a89779 245 SUPERFAMILY SSF51366 4 241 2.96E-59 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS08770 1e1ae2c760d67559276ef578b1a89779 245 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 244 4.2E-141 T 28-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CP478_RS08770 1e1ae2c760d67559276ef578b1a89779 245 Pfam PF00977 Histidine biosynthesis protein 6 235 2.2E-59 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CP478_RS08770 1e1ae2c760d67559276ef578b1a89779 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 242 31.031 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 29 617 4.2E-198 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 SUPERFAMILY SSF52518 249 509 3.11E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 37 225 3.2E-25 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 269 486 3.7E-60 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Gene3D G3DSA:3.40.50.970 249 510 1.3E-56 T 28-03-2018 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Gene3D G3DSA:3.40.920.10 26 241 2.6E-39 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 SUPERFAMILY SSF53323 31 251 3.01E-16 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Gene3D G3DSA:3.40.50.920 522 630 2.7E-8 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 SUPERFAMILY SSF52922 524 626 7.69E-15 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS13415 dc89bd9d76e194a769191d07571691dc 653 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 526 620 4.9E-8 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CP478_RS05075 e297bf43c0bb84127e7ffcf2333c1ca1 304 SUPERFAMILY SSF161098 40 290 3.55E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05075 e297bf43c0bb84127e7ffcf2333c1ca1 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 31 297 1.0E-77 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CP478_RS05075 e297bf43c0bb84127e7ffcf2333c1ca1 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 300 2.2E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05075 e297bf43c0bb84127e7ffcf2333c1ca1 304 Gene3D G3DSA:1.10.3720.10 22 295 7.0E-36 T 28-03-2018 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 SUPERFAMILY SSF54111 1 99 1.96E-45 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 4.0E-33 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 4.9E-49 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 PIRSF PIRSF001223 1 100 5.4E-50 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 Pfam PF00547 Urease, gamma subunit 1 99 8.8E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 Gene3D G3DSA:3.30.280.10 2 99 1.2E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10050 3503e10e8a78a61b1ec1de1390d68656 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.78 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS03190 5eec47edaa9cabc3b47feaaf7449772a 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 47 1.0E-11 T 28-03-2018 CP478_RS03190 5eec47edaa9cabc3b47feaaf7449772a 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 52 2.1E-10 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS03190 5eec47edaa9cabc3b47feaaf7449772a 85 SUPERFAMILY SSF143120 4 48 1.83E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS03190 5eec47edaa9cabc3b47feaaf7449772a 85 Gene3D G3DSA:3.40.1620.10 2 75 1.6E-13 T 28-03-2018 CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 SUPERFAMILY SSF54631 277 362 7.95E-7 T 28-03-2018 CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 Gene3D G3DSA:3.40.50.300 1 241 8.7E-66 T 28-03-2018 CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 SUPERFAMILY SSF52540 1 239 2.28E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 SMART SM00382 27 213 3.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 Pfam PF00005 ABC transporter 19 163 4.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS20525 f04fb7b8c87967e24f57ce2618b3af03 376 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS19235 2992cceb0f36348b378a3523b0f0fe8f 236 Gene3D G3DSA:2.40.400.10 1 236 5.1E-44 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CP478_RS19235 2992cceb0f36348b378a3523b0f0fe8f 236 Pfam PF06314 Acetoacetate decarboxylase (ADC) 14 228 4.9E-38 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CP478_RS19235 2992cceb0f36348b378a3523b0f0fe8f 236 SUPERFAMILY SSF160104 4 236 7.19E-44 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CP478_RS00210 badc00933675dc1d9e9c6c4d53cf6c0c 441 Gene3D G3DSA:1.20.1250.20 16 231 9.6E-11 T 28-03-2018 CP478_RS00210 badc00933675dc1d9e9c6c4d53cf6c0c 441 Pfam PF07690 Major Facilitator Superfamily 65 384 1.7E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS00210 badc00933675dc1d9e9c6c4d53cf6c0c 441 SUPERFAMILY SSF103473 28 434 1.57E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS00210 badc00933675dc1d9e9c6c4d53cf6c0c 441 Gene3D G3DSA:1.20.1250.20 239 435 1.4E-6 T 28-03-2018 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Hamap MF_00952 DNA topoisomerase 1 [topA]. 18 805 55.35 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF13368 Topoisomerase C-terminal repeat 793 846 6.7E-17 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF13368 Topoisomerase C-terminal repeat 714 788 2.1E-12 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF13368 Topoisomerase C-terminal repeat 651 708 1.2E-5 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF13368 Topoisomerase C-terminal repeat 860 912 2.9E-21 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 SMART SM00493 18 132 2.5E-38 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Gene3D G3DSA:1.10.460.10 503 610 4.0E-26 T 28-03-2018 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 8.8E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 530 544 8.8E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 8.8E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 337 346 8.8E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 419 435 8.8E-34 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 332 346 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Gene3D G3DSA:3.40.50.140 17 157 1.5E-38 T 28-03-2018 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 SMART SM00436 132 220 6.9E-46 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 SUPERFAMILY SSF56712 18 608 7.32E-172 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 SMART SM00437 295 567 6.7E-134 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF01751 Toprim domain 20 141 7.0E-28 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Gene3D G3DSA:1.10.460.10 163 370 5.3E-41 T 28-03-2018 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 20 669 3.4E-264 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Gene3D G3DSA:2.70.20.10 371 502 5.1E-35 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CP478_RS19900 e97dc4ade933c64181edb8f8364dfcad 934 Pfam PF01131 DNA topoisomerase 156 604 2.2E-115 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Pfam PF00571 CBS domain 221 275 4.1E-4 T 28-03-2018 IPR000644 CBS domain CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Pfam PF00571 CBS domain 292 340 0.0036 T 28-03-2018 IPR000644 CBS domain CP478_RS10020 4071435fd96ada0213d072569d24da92 455 SMART SM01091 354 444 8.3E-23 T 28-03-2018 IPR005170 Transporter-associated domain CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Pfam PF01595 Domain of unknown function DUF21 12 203 1.2E-34 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Pfam PF03471 Transporter associated domain 357 441 4.5E-19 T 28-03-2018 IPR005170 Transporter-associated domain CP478_RS10020 4071435fd96ada0213d072569d24da92 455 SUPERFAMILY SSF54631 215 355 4.8E-25 T 28-03-2018 CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Gene3D G3DSA:3.30.465.10 350 444 9.2E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS10020 4071435fd96ada0213d072569d24da92 455 SUPERFAMILY SSF56176 357 450 6.0E-19 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS10020 4071435fd96ada0213d072569d24da92 455 Gene3D G3DSA:3.10.580.10 201 349 8.4E-28 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 124 130 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 SUPERFAMILY SSF53335 28 252 1.47E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 Gene3D G3DSA:3.40.50.150 43 247 7.9E-21 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 57 2.6E-17 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 64 78 2.6E-17 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 160 184 2.6E-17 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 121 133 2.6E-17 T 28-03-2018 CP478_RS17895 140e00f1d30b5ee87678953f67e52680 553 Gene3D G3DSA:3.90.220.10 283 491 1.0E-4 T 28-03-2018 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 318 1.2E-33 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Gene3D G3DSA:2.170.190.11 44 140 1.5E-31 T 28-03-2018 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 SUPERFAMILY SSF63882 2 175 1.83E-50 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 SMART SM00852 179 322 3.3E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Gene3D G3DSA:3.40.980.10 149 332 1.7E-47 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 SUPERFAMILY SSF53218 177 327 5.1E-36 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Pfam PF03454 MoeA C-terminal region (domain IV) 336 404 7.9E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Gene3D G3DSA:2.40.340.10 335 405 8.3E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 SUPERFAMILY SSF63867 331 404 2.49E-14 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 166 8.2E-43 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02330 952bfa5adcf2b7e3b040010a13b96ea3 405 Pfam PF00994 Probable molybdopterin binding domain 180 321 5.6E-25 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:3.40.50.1000 117 252 9.9E-11 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 SUPERFAMILY SSF74650 530 794 3.14E-71 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:2.60.420.10 1245 1318 1.5E-10 T 28-03-2018 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:1.50.10.10 841 1244 1.0E-99 T 28-03-2018 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 SUPERFAMILY SSF56784 283 522 6.67E-40 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 SUPERFAMILY SSF48208 797 1313 1.36E-106 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Pfam PF02358 Trehalose-phosphatase 285 510 5.8E-69 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 284 487 1.2E-18 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 847 1259 5.3E-156 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 540 793 3.3E-68 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 SUPERFAMILY SSF56784 22 250 1.52E-17 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 1263 1314 1.3E-10 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:3.40.50.1000 281 530 3.3E-22 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:2.70.98.40 531 796 4.1E-77 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 Gene3D G3DSA:1.10.150.240 36 116 1.0E-9 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CP478_RS10935 434614ed1d5c7db4cc16337ce6c0fb38 1327 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 279 522 2.3E-63 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 76 478 6.4E-106 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 21 516 14.686 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 Gene3D G3DSA:3.60.110.10 232 511 3.2E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 Gene3D G3DSA:3.90.550.10 579 854 8.3E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 SUPERFAMILY SSF53448 612 841 8.72E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 SUPERFAMILY SSF56317 239 509 5.89E-44 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 Pfam PF00535 Glycosyl transferase family 2 614 779 1.4E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS11185 e99dd66202b34c71f7588f06c27b2a79 874 Pfam PF00795 Carbon-nitrogen hydrolase 286 486 1.9E-14 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 SUPERFAMILY SSF53300 452 612 3.56E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 Pfam PF07728 AAA domain (dynein-related subfamily) 32 166 4.6E-13 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 Gene3D G3DSA:3.40.50.410 439 604 6.5E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 SUPERFAMILY SSF52540 2 295 7.21E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 SMART SM00327 449 626 1.7E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 Pfam PF13519 von Willebrand factor type A domain 452 558 6.9E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 Gene3D G3DSA:1.10.8.80 218 306 1.3E-24 T 28-03-2018 CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 Gene3D G3DSA:3.40.50.300 1 173 2.5E-19 T 28-03-2018 CP478_RS15580 1a2fc46acfc06c8d07d0cf9dd91a1a75 629 SMART SM00382 27 176 8.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 SUPERFAMILY SSF52016 675 940 4.51E-81 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 ProSitePatterns PS01244 Aconitase family signature 2. 537 550 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 SUPERFAMILY SSF53732 6 400 1.1E-224 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 SUPERFAMILY SSF53732 445 671 1.1E-224 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Gene3D G3DSA:3.40.1060.10 234 365 4.1E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 273 286 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 144 157 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 168 176 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 287 300 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 197 210 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 211 226 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 366 380 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 537 550 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 PRINTS PR00415 Aconitase family signature 475 486 1.1E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Pfam PF00694 Aconitase C-terminal domain 735 865 3.9E-42 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Gene3D G3DSA:3.30.499.10 366 620 2.6E-68 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 ProSitePatterns PS00450 Aconitase family signature 1. 471 487 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Pfam PF00330 Aconitase family (aconitate hydratase) 67 606 7.2E-178 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Gene3D G3DSA:3.20.19.10 697 941 2.1E-88 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CP478_RS08085 543597892d83bbe87fd01ff56874a4ae 943 Gene3D G3DSA:3.30.499.10 24 233 1.3E-73 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS03885 58b7e40153b926d955544d57b6b0320e 60 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03885 58b7e40153b926d955544d57b6b0320e 60 SUPERFAMILY SSF57716 5 60 1.78E-19 T 28-03-2018 CP478_RS03885 58b7e40153b926d955544d57b6b0320e 60 Pfam PF00253 Ribosomal protein S14p/S29e 11 60 7.5E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03885 58b7e40153b926d955544d57b6b0320e 60 Gene3D G3DSA:4.10.830.10 1 60 3.1E-21 T 28-03-2018 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 SMART SM00322 59 124 1.3E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.2E-36 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.8E-94 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 SUPERFAMILY SSF54814 2 105 2.62E-36 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 SUPERFAMILY SSF54821 106 206 3.79E-36 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 Gene3D G3DSA:3.30.300.20 17 106 5.0E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 Pfam PF07650 KH domain 38 109 1.3E-18 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.048 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CP478_RS03835 b12a2fc6ad32795b54d6d69a816c43fb 274 Gene3D G3DSA:3.30.1140.32 107 208 1.7E-35 T 28-03-2018 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 Gene3D G3DSA:1.10.10.10 3 139 2.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 99 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 Pfam PF01047 MarR family 33 90 3.2E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 SMART SM00347 26 126 1.3E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS15780 70f81efe2e633d3049babd7e342e9b08 139 SUPERFAMILY SSF46785 6 136 4.26E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 124 139 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 15 279 1.5E-94 T 28-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 Pfam PF00494 Squalene/phytoene synthase 16 268 1.3E-58 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 SUPERFAMILY SSF48576 7 283 6.04E-64 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 154 179 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CP478_RS18595 da6c88b04b4078db7a2c67afc8adee77 302 Gene3D G3DSA:1.10.600.10 1 285 1.5E-72 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS17850 5f7d354cc06e2f01a95ad968f8ad3795 346 SUPERFAMILY SSF53697 65 346 7.41E-53 T 28-03-2018 CP478_RS17850 5f7d354cc06e2f01a95ad968f8ad3795 346 Gene3D G3DSA:3.40.50.10490 197 346 9.6E-26 T 28-03-2018 CP478_RS17850 5f7d354cc06e2f01a95ad968f8ad3795 346 Gene3D G3DSA:3.40.50.10490 21 172 5.3E-4 T 28-03-2018 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 17 448 58.588 T 28-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Pfam PF00881 Nitroreductase family 260 428 1.8E-26 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Gene3D G3DSA:3.40.109.10 254 446 1.7E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 SUPERFAMILY SSF144010 13 247 3.79E-69 T 28-03-2018 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Gene3D G3DSA:3.30.1330.100 7 119 5.8E-29 T 28-03-2018 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Gene3D G3DSA:3.30.1330.100 121 227 7.9E-28 T 28-03-2018 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 Pfam PF01996 F420-0:Gamma-glutamyl ligase 19 219 1.0E-39 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 SUPERFAMILY SSF55469 256 444 1.05E-36 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 12 242 2.1E-88 T 28-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CP478_RS17885 a66c345f5eae804e3375b960a918c3db 448 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 255 447 1.7E-103 T 28-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 274 1.3E-54 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 SUPERFAMILY SSF53901 242 438 5.1E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 283 395 5.2E-33 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 Gene3D G3DSA:3.40.47.10 291 438 7.9E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 SUPERFAMILY SSF53901 34 282 1.03E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 Gene3D G3DSA:3.40.47.10 28 287 4.9E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12220 a65dfc445f2d73e6c2c8559767a61fee 438 SMART SM00825 Beta-ketoacyl synthase 34 429 6.1E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16000 4d027bd48469889491f369a737e04b3b 261 SUPERFAMILY SSF53474 25 243 1.34E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16000 4d027bd48469889491f369a737e04b3b 261 SMART SM00824 Thioesterase 35 254 4.8E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CP478_RS16000 4d027bd48469889491f369a737e04b3b 261 Gene3D G3DSA:3.40.50.1820 20 252 4.3E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16000 4d027bd48469889491f369a737e04b3b 261 Pfam PF00975 Thioesterase domain 30 253 2.7E-61 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Gene3D G3DSA:2.60.120.10 533 691 1.7E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 SUPERFAMILY SSF52151 802 1059 2.88E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Gene3D G3DSA:1.20.1250.20 32 227 7.1E-36 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Pfam PF01734 Patatin-like phospholipase 806 963 3.6E-24 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 SMART SM00100 524 645 3.1E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Pfam PF00027 Cyclic nucleotide-binding domain 547 630 2.6E-19 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 SUPERFAMILY SSF51206 545 630 1.44E-19 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 43 446 1.1E-71 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 PRINTS PR01036 Tetracycline resistance protein TetB signature 45 69 7.6E-6 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 156 7.6E-6 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 PRINTS PR01036 Tetracycline resistance protein TetB signature 166 190 7.6E-6 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Gene3D G3DSA:1.20.1250.20 289 493 1.3E-17 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Pfam PF07690 Major Facilitator Superfamily 47 347 9.5E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 Gene3D G3DSA:3.40.1090.10 795 973 2.4E-35 T 28-03-2018 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 SUPERFAMILY SSF103473 34 225 1.4E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 SUPERFAMILY SSF103473 277 484 1.4E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 ProSitePatterns PS00216 Sugar transport proteins signature 1. 96 112 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS20370 69aad8271f41ced629ce16059ef136a0 1065 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 595 612 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CP478_RS11285 8c475b095b9428a520c99ac16c32d55e 244 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 242 2.7E-96 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CP478_RS11285 8c475b095b9428a520c99ac16c32d55e 244 Gene3D G3DSA:3.40.50.2300 64 241 2.1E-22 T 28-03-2018 CP478_RS11285 8c475b095b9428a520c99ac16c32d55e 244 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 3 238 7.4E-69 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.6E-31 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 143 6.7E-48 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 SUPERFAMILY SSF52080 6 144 2.75E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 Gene3D G3DSA:3.100.10.10 37 146 1.6E-29 T 28-03-2018 CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 146 18.967 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CP478_RS03915 c16d7758b8190ee33b694571f356436a 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Gene3D G3DSA:3.30.160.40 213 305 1.1E-22 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Gene3D G3DSA:3.40.190.10 99 191 2.2E-33 T 28-03-2018 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 SUPERFAMILY SSF54782 212 306 1.96E-19 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 2 296 4.5E-87 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 219 296 9.4E-22 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 PIRSF PIRSF001438 1 309 5.5E-104 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 SUPERFAMILY SSF53850 2 210 5.43E-63 T 28-03-2018 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 5.6E-24 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 5.6E-24 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 PRINTS PR00151 Porphobilinogen deaminase signature 68 87 5.6E-24 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 5.6E-24 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 1 298 34.191 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 2 204 1.8E-64 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02730 2674d15a46034e07fbf2e9e38de4f2ae 309 Gene3D G3DSA:3.40.190.10 1 98 8.4E-31 T 28-03-2018 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SMART SM00958 264 381 5.1E-24 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SMART SM00957 46 425 2.0E-140 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Pfam PF07516 SecA Wing and Scaffold domain 670 752 3.4E-14 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SUPERFAMILY SSF81767 273 389 2.62E-29 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 ProSitePatterns PS01312 SecA family signature. 523 538 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Gene3D G3DSA:1.10.3060.10 605 765 1.3E-24 T 28-03-2018 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Gene3D G3DSA:3.40.50.300 49 305 5.6E-30 T 28-03-2018 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 43 808 0.0 T 28-03-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Pfam PF01043 SecA preprotein cross-linking domain 284 381 3.6E-21 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SUPERFAMILY SSF81886 618 770 7.06E-31 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Hamap MF_01382 Protein translocase subunit SecA [secA]. 45 766 15.29 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Pfam PF07517 SecA DEAD-like domain 49 423 9.5E-82 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SUPERFAMILY SSF52540 98 264 4.28E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SUPERFAMILY SSF52540 554 593 4.28E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 207 227 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 138 152 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 100 124 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 436 449 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 154 164 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 362 384 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 PRINTS PR00906 SecA protein signature 399 416 1.6E-41 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 SUPERFAMILY SSF52540 440 598 5.55E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Gene3D G3DSA:3.40.50.300 440 539 1.2E-18 T 28-03-2018 CP478_RS09915 708f50c7fe7366eecba5ee68e135b011 808 Gene3D G3DSA:3.40.50.300 541 604 2.0E-13 T 28-03-2018 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 Gene3D G3DSA:3.40.50.170 118 308 1.2E-53 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 33 59 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 66 78 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 284 309 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 139 166 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 117 139 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 262 284 1.3E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 Gene3D G3DSA:3.30.70.260 31 117 1.9E-20 T 28-03-2018 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 Pfam PF01842 ACT domain 33 91 3.6E-10 T 28-03-2018 IPR002912 ACT domain CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 PIRSF PIRSF036480 29 310 9.2E-110 T 28-03-2018 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 SUPERFAMILY SSF55021 32 107 6.66E-13 T 28-03-2018 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 Pfam PF00551 Formyl transferase 116 292 1.1E-36 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 28 310 43.52 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 SUPERFAMILY SSF53328 116 310 8.24E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS16195 71be1dbb7c5ce8af73cc420856538ace 310 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 32 310 1.6E-129 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 Gene3D G3DSA:3.30.70.360 217 371 1.8E-40 T 28-03-2018 CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 Pfam PF01546 Peptidase family M20/M25/M40 102 457 5.7E-33 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 Pfam PF07687 Peptidase dimerisation domain 211 360 7.4E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 SUPERFAMILY SSF53187 374 461 1.63E-57 T 28-03-2018 CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 SUPERFAMILY SSF53187 23 213 1.63E-57 T 28-03-2018 CP478_RS13815 92fe417f6de4de7e869fb1a47193c56e 470 Gene3D G3DSA:3.40.630.10 24 216 2.1E-34 T 28-03-2018 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 1.7E-24 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 2.9E-33 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 125 24.181 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 9.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 9.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 9.7E-10 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 SUPERFAMILY SSF81330 11 118 4.05E-27 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CP478_RS05380 2e0d34e59e29cdf0d5bbde9cc1131f64 151 Gene3D G3DSA:1.20.5.220 104 125 1.2E-14 T 28-03-2018 CP478_RS03630 55737ed5fe8918862571946dbdffd268 280 SUPERFAMILY SSF53474 251 279 1.32E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03630 55737ed5fe8918862571946dbdffd268 280 SUPERFAMILY SSF53474 39 202 1.32E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03630 55737ed5fe8918862571946dbdffd268 280 Gene3D G3DSA:3.40.50.1820 32 280 2.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03630 55737ed5fe8918862571946dbdffd268 280 Pfam PF10503 Esterase PHB depolymerase 45 175 4.9E-18 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 230 346 1.4E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Pfam PF00550 Phosphopantetheine attachment site 877 938 9.2E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SMART SM00825 Beta-ketoacyl synthase 6 397 2.2E-151 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF53901 372 393 8.9E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF53901 3 342 8.9E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:3.40.366.10 502 639 1.4E-47 T 28-03-2018 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF52151 691 776 4.71E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF52151 502 630 4.71E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:3.40.47.10 238 395 8.0E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 506 785 1.8E-103 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:3.40.47.10 8 235 1.8E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 221 7.2E-59 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:3.30.70.250 640 682 1.5E-17 T 28-03-2018 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:3.40.366.10 683 793 2.3E-25 T 28-03-2018 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 351 469 4.9E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Pfam PF00698 Acyl transferase domain 504 777 1.9E-63 T 28-03-2018 IPR014043 Acyl transferase CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SMART SM00823 Phosphopantetheine attachment site 867 942 4.5E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 ProSitePatterns PS00012 Phosphopantetheine attachment site. 894 909 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 Gene3D G3DSA:1.10.1200.10 850 951 2.8E-14 T 28-03-2018 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF55048 629 690 1.31E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS09100 75015fbc59ea729463ef164d8398f30a 1017 SUPERFAMILY SSF47336 860 945 2.09E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20835 6acb641b3d082daa8335c2160d0b9481 261 Pfam PF01553 Acyltransferase 23 149 2.9E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS20835 6acb641b3d082daa8335c2160d0b9481 261 SUPERFAMILY SSF69593 19 207 1.96E-29 T 28-03-2018 CP478_RS20835 6acb641b3d082daa8335c2160d0b9481 261 Gene3D G3DSA:3.40.1130.10 2 217 1.2E-40 T 28-03-2018 CP478_RS20835 6acb641b3d082daa8335c2160d0b9481 261 SMART SM00563 38 152 1.0E-31 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 115 127 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 46 63 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 19 657 2.1E-166 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SUPERFAMILY SSF54292 16 89 1.71E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 163 173 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 90 1.7E-19 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 101 139 5.3E-15 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:3.30.70.20 123 222 0.0065 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:3.40.50.740 291 443 2.3E-24 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SMART SM00926 233 287 9.0E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SMART SM00929 100 140 7.8E-18 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:2.40.40.20 721 806 1.3E-19 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:3.40.50.740 451 701 6.1E-31 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:3.10.20.30 13 122 1.1E-14 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SUPERFAMILY SSF50692 705 784 2.3E-12 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Gene3D G3DSA:2.20.25.90 233 288 3.2E-9 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Pfam PF01568 Molydopterin dinucleotide binding domain 729 785 1.7E-9 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SUPERFAMILY SSF54862 93 229 2.39E-30 T 28-03-2018 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 Pfam PF00384 Molybdopterin oxidoreductase 291 432 2.2E-9 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17255 970a45425d00d07348a9bb85764a365b 806 SUPERFAMILY SSF53706 224 688 1.16E-74 T 28-03-2018 CP478_RS08235 e28e610608113de22262f40f82aada90 299 Gene3D G3DSA:2.115.10.20 164 299 2.6E-24 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CP478_RS08235 e28e610608113de22262f40f82aada90 299 SUPERFAMILY SSF75005 69 295 2.9E-33 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CP478_RS08235 e28e610608113de22262f40f82aada90 299 Gene3D G3DSA:2.115.10.20 74 163 1.4E-12 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CP478_RS08235 e28e610608113de22262f40f82aada90 299 Gene3D G3DSA:2.115.10.20 1 73 0.069 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 PIRSF PIRSF000437 11 621 6.6E-160 T 28-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 SMART SM00563 117 244 0.001 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 PIRSF PIRSF500064 7 621 2.8E-168 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 Gene3D G3DSA:3.40.1130.10 70 325 3.3E-13 T 28-03-2018 CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 Pfam PF01553 Acyltransferase 105 241 1.0E-7 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS08495 a6d2009e62bdfadf51a30e756e6bd29d 621 SUPERFAMILY SSF69593 119 300 9.68E-6 T 28-03-2018 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 Pfam PF00171 Aldehyde dehydrogenase family 4 447 5.4E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 SUPERFAMILY SSF53720 3 449 5.37E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 Gene3D G3DSA:3.40.309.10 247 433 5.9E-64 T 28-03-2018 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS15625 1f41b074b41b99c22b70ea8025d6de38 455 Gene3D G3DSA:3.40.605.10 1 246 5.7E-88 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:1.10.1780.10 1 78 1.7E-27 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:3.40.50.300 500 721 1.4E-52 T 28-03-2018 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF02151 UvrB/uvrC motif 425 457 3.1E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:1.10.8.60 352 495 2.7E-42 T 28-03-2018 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SUPERFAMILY SSF81923 3 144 1.37E-31 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 802 3.6E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SUPERFAMILY SSF52540 494 807 9.66E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 8.1E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.2E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 716 4.3E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:1.10.8.60 722 811 8.9E-23 T 28-03-2018 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:3.40.50.300 201 350 1.7E-17 T 28-03-2018 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SMART SM01086 722 818 5.5E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Gene3D G3DSA:1.10.1780.10 79 200 6.2E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SUPERFAMILY SSF52540 171 479 4.08E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 2.0E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 2.0E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 2.0E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 2.0E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SMART SM00382 545 723 5.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 SMART SM00382 208 353 9.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 325 6.1E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS19645 353bcd17fa21899a086361fc3000d5e5 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 303 315 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 PIRSF PIRSF006107 191 690 7.5E-159 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 PIRSF PIRSF006107 3 186 2.9E-11 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Pfam PF13500 AAA domain 6 202 2.3E-20 T 28-03-2018 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Gene3D G3DSA:3.40.718.10 379 660 1.2E-64 T 28-03-2018 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 SUPERFAMILY SSF53659 366 685 2.8E-94 T 28-03-2018 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Pfam PF01515 Phosphate acetyl/butaryl transferase 365 682 1.3E-134 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 SUPERFAMILY SSF52540 6 207 6.37E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Pfam PF07085 DRTGG domain 207 319 4.2E-23 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Gene3D G3DSA:3.40.50.300 2 203 2.7E-28 T 28-03-2018 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 Gene3D G3DSA:3.40.1390.20 204 342 2.8E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 381 682 9.3E-122 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CP478_RS02175 7c6891ea29d567db217d972892d1a051 690 SUPERFAMILY SSF75138 202 325 3.37E-21 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 394 406 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 SUPERFAMILY SSF54368 5 103 1.09E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 477 2.1E-211 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 265 280 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 1.1E-27 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 Pfam PF00120 Glutamine synthetase, catalytic domain 106 475 6.7E-134 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 Gene3D G3DSA:3.30.590.10 108 466 5.4E-123 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 Gene3D G3DSA:3.10.20.70 5 107 2.9E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 SUPERFAMILY SSF55931 106 477 4.22E-136 T 28-03-2018 CP478_RS12065 a7632b31ce95ad4f254a418119179938 478 SMART SM01230 105 387 6.5E-144 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12815 d0fabad4fc0b5ca3b912c67bcc715124 508 Gene3D G3DSA:3.40.720.10 132 429 6.8E-11 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS12815 d0fabad4fc0b5ca3b912c67bcc715124 508 Pfam PF04185 Phosphoesterase family 43 424 4.1E-128 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF51735 1436 1676 1.8E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF51735 1203 1425 1.84E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.366.10 742 864 1.8E-21 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.50.720 1064 1432 0.002 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF14765 Polyketide synthase dehydratase 910 1196 1.8E-61 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:1.10.1200.10 1703 1822 3.6E-14 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 285 2.7E-96 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF08659 KR domain 1439 1616 6.3E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.10.129.10 910 1040 7.2E-8 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF00698 Acyl transferase domain 566 873 1.8E-95 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SMART SM00826 910 1076 1.2E-40 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF52151 566 690 1.05E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF52151 753 851 1.05E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 411 1.6E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.47.10 31 297 1.9E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.47.10 300 462 6.4E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.30.70.250 698 741 1.2E-13 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 520 2.9E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 857 2.4E-98 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1740 1755 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.50.720 1433 1684 7.9E-41 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF47336 1703 1791 3.14E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SMART SM00823 Phosphopantetheine attachment site 1709 1785 1.5E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF53901 35 410 1.87E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Gene3D G3DSA:3.40.366.10 565 697 7.6E-35 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 Pfam PF00550 Phosphopantetheine attachment site 1712 1779 6.4E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1439 1617 3.9E-40 T 28-03-2018 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SUPERFAMILY SSF55048 688 752 1.44E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16030 0e9c0b38c35fa00567582e86fbf1bdf7 1827 SMART SM00825 Beta-ketoacyl synthase 38 464 3.8E-217 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 PIRSF PIRSF000980 2 1088 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 SUPERFAMILY SSF52540 3 322 2.5E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 Gene3D G3DSA:1.10.10.160 89 195 5.5E-18 T 28-03-2018 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 Gene3D G3DSA:1.10.486.10 413 618 5.8E-55 T 28-03-2018 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 SUPERFAMILY SSF52540 327 764 4.91E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 2 1097 15.94 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 3 1046 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 3 750 7.9E-200 T 28-03-2018 CP478_RS03390 c324e6960c748f78d0962e41a8946b2a 1097 SUPERFAMILY SSF52980 784 1093 1.29E-65 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS06635 ba62ed6459718a65966d81972d8990d8 75 Pfam PF11314 Protein of unknown function (DUF3117) 24 73 3.3E-28 T 28-03-2018 IPR021465 Protein of unknown function DUF3117 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 Gene3D G3DSA:1.10.8.100 230 291 9.9E-16 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 293 48.331 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 SUPERFAMILY SSF53335 28 290 1.02E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 Pfam PF00398 Ribosomal RNA adenine dimethylase 30 287 7.0E-39 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 SMART SM00650 44 219 1.2E-71 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 Gene3D G3DSA:3.40.50.150 16 226 6.0E-48 T 28-03-2018 CP478_RS05525 653aa56ded34cdcf86628a056a0356d1 317 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 290 2.4E-82 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CP478_RS05105 16172d909506a0aaf574f0aa9679e4d6 301 SUPERFAMILY SSF161098 38 287 1.44E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05105 16172d909506a0aaf574f0aa9679e4d6 301 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 32 291 4.9E-62 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CP478_RS05105 16172d909506a0aaf574f0aa9679e4d6 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 297 6.5E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05105 16172d909506a0aaf574f0aa9679e4d6 301 Gene3D G3DSA:1.10.3720.10 29 301 4.9E-37 T 28-03-2018 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 24 402 2.5E-183 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 SUPERFAMILY SSF53686 24 403 2.23E-144 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 Gene3D G3DSA:3.40.50.1100 212 406 4.2E-41 T 28-03-2018 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 65 391 1.8E-51 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 Gene3D G3DSA:3.40.50.1100 23 82 5.4E-6 T 28-03-2018 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 Gene3D G3DSA:3.40.50.1100 83 211 4.0E-41 T 28-03-2018 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 404 52.158 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 PIRSF PIRSF001413 3 407 5.9E-160 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08815 730e13a4e7625f457e6a33de2b885160 410 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 94 108 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS01190 76e18e99938d9f8d9b1243de08a5cd20 403 SUPERFAMILY SSF53474 124 371 7.13E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01190 76e18e99938d9f8d9b1243de08a5cd20 403 Gene3D G3DSA:3.40.50.1820 97 399 1.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01190 76e18e99938d9f8d9b1243de08a5cd20 403 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 224 239 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CP478_RS01190 76e18e99938d9f8d9b1243de08a5cd20 403 Pfam PF07859 alpha/beta hydrolase fold 160 369 1.4E-24 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 SUPERFAMILY SSF56801 10 529 7.98E-108 T 28-03-2018 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Gene3D G3DSA:2.30.38.10 336 423 4.1E-19 T 28-03-2018 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Pfam PF00501 AMP-binding enzyme 21 430 1.7E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Gene3D G3DSA:3.40.50.980 13 178 9.6E-34 T 28-03-2018 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Gene3D G3DSA:3.30.300.30 425 540 4.5E-18 T 28-03-2018 CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 519 3.8E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS00550 b58f544fb1d9a29b4ba3bc00c5352cc6 540 Gene3D G3DSA:3.40.50.980 179 335 3.3E-31 T 28-03-2018 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 TIGRFAM TIGR00833 actII: transport protein 27 934 0.0 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 SUPERFAMILY SSF82866 725 934 4.71E-29 T 28-03-2018 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 Gene3D G3DSA:1.20.120.330 511 723 8.5E-4 T 28-03-2018 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 SUPERFAMILY SSF82866 158 357 1.15E-26 T 28-03-2018 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 Pfam PF03176 MMPL family 59 387 4.8E-114 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 Pfam PF03176 MMPL family 607 942 1.0E-105 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 Gene3D G3DSA:1.20.1640.10 151 369 8.0E-27 T 28-03-2018 CP478_RS12760 f085aa644e9b38ae9175b865f77b9e9d 962 Gene3D G3DSA:1.20.1640.10 724 931 6.6E-27 T 28-03-2018 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Pfam PF00154 recA bacterial DNA recombination protein 9 252 5.9E-131 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SUPERFAMILY SSF52540 6 258 4.1E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:3.40.50.300 28 251 1.9E-42 T 28-03-2018 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Hamap MF_00268 Protein RecA [recA]. 7 771 43.141 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 95 124 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 212 240 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 685 714 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 129 158 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 167 196 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00142 RecA protein signature 739 756 3.1E-81 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SUPERFAMILY SSF51294 251 374 2.75E-36 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SUPERFAMILY SSF51294 627 691 2.75E-36 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SMART SM00305 652 697 1.1E-9 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:3.10.28.10 462 575 1.7E-14 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:2.170.16.10 252 353 2.4E-8 T 28-03-2018 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 253 1.3E-136 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SMART SM00382 59 230 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:2.170.16.10 576 691 2.4E-6 T 28-03-2018 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SUPERFAMILY SSF55608 458 563 2.72E-12 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 671 692 2.1E-7 T 28-03-2018 IPR030934 Intein C-terminal splicing region CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Pfam PF14890 Intein splicing domain 265 691 3.2E-10 T 28-03-2018 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SMART SM00306 250 348 1.0E-18 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 ProSitePatterns PS00321 recA signature. 215 223 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 495 510 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 315 328 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 686 695 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 363 375 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 464 476 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 PRINTS PR00379 Intein signature 668 685 3.3E-20 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Pfam PF14528 LAGLIDADG-like domain 464 554 9.6E-15 T 28-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:3.10.28.10 354 412 0.0023 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 Gene3D G3DSA:3.30.250.10 710 768 3.5E-25 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 252 328 2.9E-11 T 28-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS14995 6a64f717527eb4eec2bdfd8fa60ef758 790 SUPERFAMILY SSF54752 710 768 6.93E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 SUPERFAMILY SSF110921 495 642 3.4E-43 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 SUPERFAMILY SSF89000 437 489 9.81E-15 T 28-03-2018 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 79 95 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 282 295 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 Gene3D G3DSA:3.20.20.70 49 425 2.2E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 SUPERFAMILY SSF51569 61 369 3.85E-96 T 28-03-2018 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 43 644 54.125 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 Gene3D G3DSA:3.20.20.150 468 577 0.058 T 28-03-2018 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 SMART SM00917 474 643 8.9E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 42 644 0.0 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 Pfam PF08502 LeuA allosteric (dimerisation) domain 474 642 2.7E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CP478_RS20270 14523ba3e32fc6718c05f3f4cee3bb7b 644 Pfam PF00682 HMGL-like 73 352 1.8E-75 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 740 6.4E-223 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 SUPERFAMILY SSF52540 813 1062 5.95E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 Pfam PF01580 FtsK/SpoIIIE family 834 1096 1.9E-84 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 Pfam PF01580 FtsK/SpoIIIE family 518 702 1.2E-15 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 SUPERFAMILY SSF52540 1161 1333 8.13E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 Gene3D G3DSA:3.40.50.300 448 712 6.0E-16 T 28-03-2018 CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 Gene3D G3DSA:3.40.50.300 1124 1322 3.3E-8 T 28-03-2018 CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 801 1387 5.9E-173 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 SUPERFAMILY SSF52540 503 705 2.26E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21280 62f9b0726ec9ec0f76ff32323b2c83ba 1396 Gene3D G3DSA:3.40.50.300 875 1078 0.036 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.40.366.10 82 218 4.7E-44 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF55048 209 270 2.35E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF00550 Phosphopantetheine attachment site 1524 1585 1.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM00826 445 605 6.4E-80 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.40.50.720 612 904 0.2 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF52151 263 373 7.59E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF52151 84 204 7.59E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF14765 Polyketide synthase dehydratase 445 719 3.4E-58 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1228 1409 4.1E-58 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF50129 912 1042 1.98E-26 T 28-03-2018 IPR011032 GroES-like CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.40.50.720 1220 1483 4.5E-49 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1544 1559 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM00823 Phosphopantetheine attachment site 1517 1589 1.2E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 86 377 5.1E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.40.366.10 260 378 2.7E-29 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:1.10.1200.10 1509 1616 4.3E-22 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 930 985 1.5E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF47336 1511 1594 1.03E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.90.180.10 905 1218 5.9E-59 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF51735 735 890 1.22E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF00698 Acyl transferase domain 86 395 1.0E-58 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Gene3D G3DSA:3.30.70.250 219 259 2.2E-17 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM01294 1518 1585 5.4E-5 T 28-03-2018 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF51735 1224 1462 1.15E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF00107 Zinc-binding dehydrogenase 1048 1139 1.5E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SUPERFAMILY SSF51735 1008 1144 6.72E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 SMART SM00829 910 1215 1.8E-178 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS16095 bf7bda490a8c1c31c20f4411b16bc88d 1616 Pfam PF08659 KR domain 1228 1407 1.7E-60 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 Gene3D G3DSA:3.40.50.1370 141 305 1.4E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 1.8E-47 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 Gene3D G3DSA:3.40.50.1370 1 140 1.7E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 1.6E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 1.6E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 1.6E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 1.6E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 1.6E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 76.948 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 SUPERFAMILY SSF53671 2 305 1.57E-100 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 2.8E-52 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 3.8E-115 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 3.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 3.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 3.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS09060 e875e39ecfc849e0b0fccf3955ca9676 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 3.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS04730 d7d91e6a0aff0c3a5a8cb01192744c8c 407 Pfam PF06737 Transglycosylase-like domain 39 114 2.3E-34 T 28-03-2018 IPR010618 Transglycosylase-like CP478_RS04730 d7d91e6a0aff0c3a5a8cb01192744c8c 407 Gene3D G3DSA:1.10.530.10 6 120 7.3E-29 T 28-03-2018 CP478_RS04730 d7d91e6a0aff0c3a5a8cb01192744c8c 407 SUPERFAMILY SSF53955 39 117 1.01E-30 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS15090 fd1c89f1809d06a531acf144ac803d90 250 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 7 238 28.488 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS15090 fd1c89f1809d06a531acf144ac803d90 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 5.5E-68 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS15090 fd1c89f1809d06a531acf144ac803d90 250 SUPERFAMILY SSF69796 33 237 1.83E-63 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS15090 fd1c89f1809d06a531acf144ac803d90 250 Pfam PF02511 Thymidylate synthase complementing protein 32 224 2.3E-56 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 Pfam PF11856 Protein of unknown function (DUF3376) 377 852 4.3E-30 T 28-03-2018 IPR024282 Domain of unknown function DUF3376 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 Gene3D G3DSA:3.40.1090.10 38 444 1.1E-27 T 28-03-2018 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 Pfam PF01734 Patatin-like phospholipase 52 318 2.4E-17 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 SUPERFAMILY SSF52151 110 354 9.94E-17 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 SUPERFAMILY SSF52151 54 78 9.94E-17 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS19030 511898966b5eb1945a6ea0a724bf014b 1082 TIGRFAM TIGR03607 TIGR03607: patatin-related protein 45 754 1.3E-186 T 28-03-2018 IPR019894 Patatin-related protein CP478_RS01720 0be0a39c3bf6bbf573464568544b5dff 190 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.467 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CP478_RS01720 0be0a39c3bf6bbf573464568544b5dff 190 SUPERFAMILY SSF51283 2 184 4.71E-55 T 28-03-2018 IPR029054 dUTPase-like CP478_RS01720 0be0a39c3bf6bbf573464568544b5dff 190 Gene3D G3DSA:2.70.40.10 1 159 7.0E-46 T 28-03-2018 CP478_RS01720 0be0a39c3bf6bbf573464568544b5dff 190 Pfam PF00692 dUTPase 70 177 1.2E-10 T 28-03-2018 IPR029054 dUTPase-like CP478_RS01720 0be0a39c3bf6bbf573464568544b5dff 190 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 3.2E-64 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CP478_RS18445 3381263874cacd4d8a2d3a14f9d6c0bc 214 SUPERFAMILY SSF55469 7 211 1.1E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS18445 3381263874cacd4d8a2d3a14f9d6c0bc 214 Pfam PF00881 Nitroreductase family 14 189 4.6E-23 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CP478_RS18445 3381263874cacd4d8a2d3a14f9d6c0bc 214 Gene3D G3DSA:3.40.109.10 5 213 8.7E-36 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 537 6.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Gene3D G3DSA:3.30.450.40 208 379 2.8E-16 T 28-03-2018 IPR029016 GAF domain-like CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Pfam PF13185 GAF domain 62 199 1.1E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Pfam PF07730 Histidine kinase 384 444 3.4E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SUPERFAMILY SSF55781 218 394 6.11E-16 T 28-03-2018 IPR029016 GAF domain-like CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SUPERFAMILY SSF55874 467 572 4.19E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SMART SM00065 61 208 6.6E-22 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SMART SM00065 209 376 0.012 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Pfam PF13492 GAF domain 310 365 2.4E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Gene3D G3DSA:3.30.565.10 451 573 1.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SMART SM00387 485 573 0.0084 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 SUPERFAMILY SSF55781 43 225 3.27E-40 T 28-03-2018 IPR029016 GAF domain-like CP478_RS11065 5f966ad6a2c3b1e017c055e231f03c65 573 Gene3D G3DSA:3.30.450.40 17 207 5.3E-33 T 28-03-2018 IPR029016 GAF domain-like CP478_RS16140 262c41725e242de8314aefe4c4b5c182 241 Gene3D G3DSA:3.40.50.150 9 166 2.9E-19 T 28-03-2018 CP478_RS16140 262c41725e242de8314aefe4c4b5c182 241 SUPERFAMILY SSF53335 14 154 2.43E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16140 262c41725e242de8314aefe4c4b5c182 241 Pfam PF13649 Methyltransferase domain 43 123 4.4E-11 T 28-03-2018 CP478_RS04340 d73ebd8f502396df74f6ba116fd305f6 335 SUPERFAMILY SSF54909 7 307 2.68E-103 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS04340 d73ebd8f502396df74f6ba116fd305f6 335 Pfam PF04261 Dyp-type peroxidase family 9 305 2.0E-103 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CP478_RS04340 d73ebd8f502396df74f6ba116fd305f6 335 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 9 305 4.0E-91 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CP478_RS04340 d73ebd8f502396df74f6ba116fd305f6 335 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 322 332 0.075 T 28-03-2018 CP478_RS12160 d2a8815a5a22b842ddf9db8def7b6957 313 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 13 308 6.3E-52 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CP478_RS12160 d2a8815a5a22b842ddf9db8def7b6957 313 Pfam PF03186 CobD/Cbib protein 14 292 5.4E-88 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CP478_RS12160 d2a8815a5a22b842ddf9db8def7b6957 313 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 313 87.665 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.1E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 SUPERFAMILY SSF51735 4 246 2.17E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 243 3.7E-67 T 28-03-2018 CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 Gene3D G3DSA:3.40.50.720 1 42 6.0E-11 T 28-03-2018 CP478_RS04185 3b4c3f460f73b44b300d3b16e52a2810 248 Gene3D G3DSA:3.40.50.720 43 248 1.5E-59 T 28-03-2018 CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 SUPERFAMILY SSF52540 20 333 8.83E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 25 567 43.015 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 17 569 3.4E-183 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 Gene3D G3DSA:3.40.50.300 338 558 9.6E-26 T 28-03-2018 CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 SUPERFAMILY SSF52540 281 349 2.12E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 SUPERFAMILY SSF52540 402 567 2.12E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 Pfam PF13604 AAA domain 151 360 6.9E-37 T 28-03-2018 CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 Pfam PF13538 UvrD-like helicase C-terminal domain 499 545 3.4E-15 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CP478_RS03380 ee5b4832810bf5bdffc55fb67cf75ac2 575 Gene3D G3DSA:3.40.50.300 115 337 3.2E-41 T 28-03-2018 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 340 361 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 263 281 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 2.4E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Gene3D G3DSA:1.10.1390.10 513 553 1.8E-16 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Pfam PF00342 Phosphoglucose isomerase 54 542 7.7E-201 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 267 280 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 40.932 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Gene3D G3DSA:3.40.50.10490 261 512 2.2E-110 T 28-03-2018 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 SUPERFAMILY SSF53697 8 549 1.0E-201 T 28-03-2018 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Gene3D G3DSA:3.40.50.10490 146 260 4.0E-52 T 28-03-2018 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 Gene3D G3DSA:3.40.50.10490 2 145 1.1E-44 T 28-03-2018 CP478_RS05155 d23a9af8e3587c3ebcbc69b7d74f5f9a 553 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 Pfam PF01546 Peptidase family M20/M25/M40 75 384 2.0E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 SUPERFAMILY SSF55031 184 301 2.84E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 PIRSF PIRSF005962 6 389 8.3E-96 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 375 7.7E-98 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 SUPERFAMILY SSF53187 8 199 2.74E-71 T 28-03-2018 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 SUPERFAMILY SSF53187 300 385 2.74E-71 T 28-03-2018 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 Gene3D G3DSA:3.40.630.10 237 389 4.0E-19 T 28-03-2018 CP478_RS18105 dc7796a53b511c401779442a69d0af2b 389 Gene3D G3DSA:3.40.630.10 1 236 7.3E-44 T 28-03-2018 CP478_RS18195 f5be9ba47b5bb469175c2c826f4be62f 80 Gene3D G3DSA:1.10.1220.10 1 45 1.7E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Gene3D G3DSA:3.30.450.20 11 147 3.9E-21 T 28-03-2018 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Pfam PF13466 STAS domain 559 630 7.6E-11 T 28-03-2018 IPR002645 STAS domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 SUPERFAMILY SSF52091 559 630 1.49E-9 T 28-03-2018 IPR002645 STAS domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 SMART SM00331 173 396 1.4E-58 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Pfam PF08448 PAS fold 21 135 3.0E-12 T 28-03-2018 IPR013656 PAS fold-4 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 SUPERFAMILY SSF55785 16 131 1.28E-8 T 28-03-2018 IPR000014 PAS domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Pfam PF13581 Histidine kinase-like ATPase domain 409 522 1.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Gene3D G3DSA:3.60.40.10 168 397 1.4E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 SUPERFAMILY SSF55874 430 526 3.83E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Gene3D G3DSA:3.30.565.10 398 539 2.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 202 396 1.3E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 Gene3D G3DSA:3.30.750.24 555 650 1.3E-9 T 28-03-2018 IPR002645 STAS domain CP478_RS07485 ef7f9d599a957bd01ef93e5db246f76e 653 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 139 1.9E-7 T 28-03-2018 IPR000014 PAS domain CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 Gene3D G3DSA:1.10.357.10 66 202 2.5E-18 T 28-03-2018 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 Gene3D G3DSA:1.10.10.60 4 65 9.2E-21 T 28-03-2018 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 89 203 6.6E-8 T 28-03-2018 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 4.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 SUPERFAMILY SSF48498 93 202 2.97E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 SUPERFAMILY SSF46689 6 88 1.54E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01625 fe07e3729698ddffbc314e4f37b0e926 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 Gene3D G3DSA:1.10.10.10 1 83 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 SUPERFAMILY SSF46785 3 87 1.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 SUPERFAMILY SSF53850 88 298 4.71E-24 T 28-03-2018 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 Pfam PF03466 LysR substrate binding domain 87 296 1.4E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 Gene3D G3DSA:3.40.190.10 88 176 1.7E-11 T 28-03-2018 CP478_RS00645 40139ba8f6434d44d3918c62e4d5ec3c 314 Gene3D G3DSA:3.40.190.10 177 272 3.4E-11 T 28-03-2018 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 Gene3D G3DSA:3.30.460.10 206 402 1.2E-53 T 28-03-2018 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 SUPERFAMILY SSF81301 213 401 5.56E-39 T 28-03-2018 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 SUPERFAMILY SSF52540 1 195 8.56E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 23.965 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 Gene3D G3DSA:3.40.50.300 1 196 1.7E-38 T 28-03-2018 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 Pfam PF01121 Dephospho-CoA kinase 4 178 5.3E-61 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 184 1.1E-40 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CP478_RS08920 c87baa6c899e3c0d46d1973a6407a980 407 Pfam PF04229 GrpB protein 211 395 3.7E-40 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 Pfam PF00069 Protein kinase domain 13 261 2.1E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 PIRSF PIRSF000654 19 262 3.0E-25 T 28-03-2018 CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 Gene3D G3DSA:1.10.510.10 102 270 5.7E-49 T 28-03-2018 CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 Gene3D G3DSA:3.30.200.20 4 101 3.5E-20 T 28-03-2018 CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 SUPERFAMILY SSF56112 11 274 7.69E-76 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS00090 040e8f7c0d67313ac985aa4e141b99fa 431 SMART SM00220 13 272 7.8E-64 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS05125 486e08cf71de037e5e0658feefacd0cb 288 SUPERFAMILY SSF51679 6 285 2.09E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS05125 486e08cf71de037e5e0658feefacd0cb 288 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 255 1.0E-50 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CP478_RS05125 486e08cf71de037e5e0658feefacd0cb 288 Gene3D G3DSA:3.20.20.30 2 241 1.9E-58 T 28-03-2018 CP478_RS05125 486e08cf71de037e5e0658feefacd0cb 288 Pfam PF00296 Luciferase-like monooxygenase 10 226 4.1E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 SUPERFAMILY SSF51735 4 251 3.23E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 Pfam PF00106 short chain dehydrogenase 9 202 5.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.9E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 Gene3D G3DSA:3.40.50.720 168 229 6.0E-9 T 28-03-2018 CP478_RS05150 aa1d60849f76c407468870fb4b94d217 253 Gene3D G3DSA:3.40.50.720 5 167 1.5E-34 T 28-03-2018 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF47336 18 131 3.53E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 118 366 3.1E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF00698 Acyl transferase domain 713 1034 1.2E-52 T 28-03-2018 IPR014043 Acyl transferase CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:3.40.50.1820 1457 1720 1.4E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SMART SM00823 Phosphopantetheine attachment site 1235 1290 0.0011 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SMART SM00823 Phosphopantetheine attachment site 24 95 1.4E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:3.40.47.10 110 378 3.8E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:3.40.366.10 712 1033 1.2E-52 T 28-03-2018 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 278 294 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:1.10.1200.10 1187 1312 2.9E-15 T 28-03-2018 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:3.40.47.10 381 542 4.3E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF53474 1458 1719 1.38E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF55048 845 901 1.44E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF52151 906 1000 2.51E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF52151 713 837 2.51E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF53901 519 540 1.7E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF53901 118 487 1.7E-91 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 494 552 1.1E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 715 1019 3.3E-76 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:1.10.1200.10 1313 1453 0.15 T 28-03-2018 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF00550 Phosphopantetheine attachment site 1241 1283 1.1E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF00550 Phosphopantetheine attachment site 25 91 1.1E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SUPERFAMILY SSF47336 1232 1310 5.63E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 SMART SM00825 Beta-ketoacyl synthase 119 544 9.4E-182 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF00975 Thioesterase domain 1470 1565 2.9E-17 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Gene3D G3DSA:1.10.1200.10 2 99 2.3E-12 T 28-03-2018 CP478_RS20755 957aa8f23e3bd6efb17d5eb07ba60aa7 1733 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 374 491 2.8E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 Pfam PF00582 Universal stress protein family 10 141 7.3E-18 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 Gene3D G3DSA:3.40.50.620 1 141 1.9E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 SUPERFAMILY SSF52402 154 274 7.03E-7 T 28-03-2018 CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 PRINTS PR01438 Universal stress protein signature 101 113 2.2E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 PRINTS PR01438 Universal stress protein signature 7 25 2.2E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 PRINTS PR01438 Universal stress protein signature 119 141 2.2E-6 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 Gene3D G3DSA:3.40.50.620 152 275 4.6E-5 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11070 ac3814d672301962db4e64c47944c2e9 279 SUPERFAMILY SSF52402 9 147 7.45E-20 T 28-03-2018 CP478_RS17860 d4ccc6046f361853967d3b9d24aaa592 163 Pfam PF12005 Protein of unknown function (DUF3499) 22 160 2.1E-47 T 28-03-2018 IPR021888 Protein of unknown function DUF3499 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 17 445 1.2E-235 T 28-03-2018 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 PIRSF PIRSF000521 2 448 3.8E-166 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 SUPERFAMILY SSF53383 39 445 8.5E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 Pfam PF00202 Aminotransferase class-III 34 444 1.6E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 268 305 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 Gene3D G3DSA:3.40.640.10 62 337 3.4E-70 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS18030 4045e6559d1b00d87f6e3ec62b77bf35 449 Gene3D G3DSA:3.90.1150.10 338 449 1.3E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS08400 f1a97c6cbec43811a9d064f734b1fd03 144 SUPERFAMILY SSF54637 14 144 3.64E-27 T 28-03-2018 IPR029069 HotDog domain CP478_RS08400 f1a97c6cbec43811a9d064f734b1fd03 144 Gene3D G3DSA:3.10.129.10 3 144 2.8E-29 T 28-03-2018 CP478_RS08400 f1a97c6cbec43811a9d064f734b1fd03 144 Pfam PF03061 Thioesterase superfamily 59 134 3.9E-12 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CP478_RS08400 f1a97c6cbec43811a9d064f734b1fd03 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 28 141 6.4E-13 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CP478_RS13770 0a3ea529c3c0fa550fd8fdaaa45855a0 415 Pfam PF01381 Helix-turn-helix 29 82 1.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS13770 0a3ea529c3c0fa550fd8fdaaa45855a0 415 Pfam PF06114 IrrE N-terminal-like domain 190 325 6.4E-21 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CP478_RS13770 0a3ea529c3c0fa550fd8fdaaa45855a0 415 Gene3D G3DSA:1.10.260.40 20 92 1.6E-10 T 28-03-2018 CP478_RS13770 0a3ea529c3c0fa550fd8fdaaa45855a0 415 SMART SM00530 28 83 1.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS13770 0a3ea529c3c0fa550fd8fdaaa45855a0 415 SUPERFAMILY SSF47413 27 90 1.69E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS14740 5c5e91c369e8e8cb698a014279bec114 301 Gene3D G3DSA:3.40.50.300 14 256 1.7E-59 T 28-03-2018 CP478_RS14740 5c5e91c369e8e8cb698a014279bec114 301 SUPERFAMILY SSF52540 17 233 2.03E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14740 5c5e91c369e8e8cb698a014279bec114 301 SMART SM00382 44 222 3.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS14740 5c5e91c369e8e8cb698a014279bec114 301 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS14740 5c5e91c369e8e8cb698a014279bec114 301 Pfam PF00005 ABC transporter 36 175 1.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS19985 aa377c5a41850ee6aed21cd5f7f5bc33 287 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 27 226 2.4E-73 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CP478_RS19985 aa377c5a41850ee6aed21cd5f7f5bc33 287 Gene3D G3DSA:3.40.50.1000 24 248 2.8E-18 T 28-03-2018 IPR023214 HAD-like domain CP478_RS19985 aa377c5a41850ee6aed21cd5f7f5bc33 287 Pfam PF12710 haloacid dehalogenase-like hydrolase 28 213 1.8E-32 T 28-03-2018 CP478_RS19985 aa377c5a41850ee6aed21cd5f7f5bc33 287 SUPERFAMILY SSF56784 24 236 5.11E-29 T 28-03-2018 IPR023214 HAD-like domain CP478_RS19985 aa377c5a41850ee6aed21cd5f7f5bc33 287 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 27 215 1.6E-22 T 28-03-2018 CP478_RS16090 ca0d02ecf14567d84b4af1641fcc117e 233 Pfam PF07161 LppX_LprAFG lipoprotein 48 232 4.6E-59 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS16090 ca0d02ecf14567d84b4af1641fcc117e 233 SUPERFAMILY SSF89392 47 233 2.35E-59 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CP478_RS16090 ca0d02ecf14567d84b4af1641fcc117e 233 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 1 233 5.0E-121 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 PIRSF PIRSF000728 14 293 4.2E-97 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 TIGRFAM TIGR00761 argB: acetylglutamate kinase 30 268 1.1E-82 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 Hamap MF_00082_B Acetylglutamate kinase [argB]. 27 293 33.017 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 Gene3D G3DSA:3.40.1160.10 2 294 8.1E-72 T 28-03-2018 CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 Pfam PF00696 Amino acid kinase family 29 270 8.7E-47 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 SUPERFAMILY SSF53633 12 293 3.27E-83 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 5.8E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS09050 e437699d3f6a9c505a009872d5a26d84 294 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 5.8E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CP478_RS20010 f6200403804ba5e804aafcb733a06444 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 9.6E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20010 f6200403804ba5e804aafcb733a06444 308 SUPERFAMILY SSF161098 91 289 5.01E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20010 f6200403804ba5e804aafcb733a06444 308 Gene3D G3DSA:1.10.3720.10 4 295 1.3E-37 T 28-03-2018 CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 Gene3D G3DSA:3.40.50.300 1 173 1.3E-34 T 28-03-2018 CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 191 2.0E-19 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 SUPERFAMILY SSF52317 254 448 7.43E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 SUPERFAMILY SSF52540 4 199 3.55E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 450 2.3E-112 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 Gene3D G3DSA:3.40.50.880 174 402 2.0E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 256 435 1.4E-24 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CP478_RS15570 e61aee197c32683b3a8ad53371e65bc6 457 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 3 440 40.871 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CP478_RS06050 83429e595e99a8408adc1d8138a655da 103 Gene3D G3DSA:2.30.30.110 5 101 2.8E-13 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS06050 83429e595e99a8408adc1d8138a655da 103 SUPERFAMILY SSF50118 8 98 1.2E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS06050 83429e595e99a8408adc1d8138a655da 103 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 84 1.0E-9 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 SUPERFAMILY SSF140459 8 84 6.8E-25 T 28-03-2018 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 PRINTS PR01228 Eggshell protein signature 445 463 5.6E-5 T 28-03-2018 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 PRINTS PR01228 Eggshell protein signature 305 316 5.6E-5 T 28-03-2018 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 PRINTS PR01228 Eggshell protein signature 402 412 5.6E-5 T 28-03-2018 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 PRINTS PR01228 Eggshell protein signature 371 386 5.6E-5 T 28-03-2018 CP478_RS15595 cb7f188c93576e5cc948b632fb09d881 615 Pfam PF00934 PE family 1 93 2.7E-32 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS13615 b2d12b0378846edc70bbf8a1a2c99fca 1660 SUPERFAMILY SSF140459 8 84 3.14E-25 T 28-03-2018 CP478_RS13615 b2d12b0378846edc70bbf8a1a2c99fca 1660 Pfam PF00934 PE family 1 92 8.1E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS20790 d281342ae3b71e7584099ae8a4f0c99a 165 Gene3D G3DSA:1.20.144.10 4 163 2.6E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS20790 d281342ae3b71e7584099ae8a4f0c99a 165 SMART SM00014 51 153 3.2E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS20790 d281342ae3b71e7584099ae8a4f0c99a 165 Pfam PF01569 PAP2 superfamily 53 152 1.8E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS20790 d281342ae3b71e7584099ae8a4f0c99a 165 SUPERFAMILY SSF48317 3 152 5.23E-37 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS13845 ecccabd0e0f605ac1b595d801395895a 75 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 4 44 4.5E-8 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS10500 e174e62c5b6a854ce46dcfd67c03bd2b 174 Gene3D G3DSA:3.40.50.880 1 37 1.9E-4 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS10500 e174e62c5b6a854ce46dcfd67c03bd2b 174 SUPERFAMILY SSF52317 36 113 3.62E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS10500 e174e62c5b6a854ce46dcfd67c03bd2b 174 Gene3D G3DSA:3.40.50.880 38 156 2.6E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Gene3D G3DSA:1.10.10.10 2 87 5.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 SMART SM00899 152 228 6.8E-12 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 72 140 5.5E-31 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 SMART SM00529 33 132 1.3E-47 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 SUPERFAMILY SSF46785 11 71 1.37E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 61 3.2E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 42 3.2E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 SUPERFAMILY SSF47979 72 145 1.7E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 SUPERFAMILY SSF50037 156 226 2.15E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Gene3D G3DSA:2.30.30.90 133 228 8.0E-26 T 28-03-2018 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Pfam PF04023 FeoA domain 152 226 6.9E-21 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Gene3D G3DSA:1.10.60.10 88 132 9.0E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CP478_RS15265 32f12a951d65069940ab83eea45869f0 228 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 9 69 3.3E-23 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 94 643 1.2E-170 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 94 644 3.0E-153 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 SUPERFAMILY SSF81653 150 245 3.66E-27 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 Gene3D G3DSA:2.70.150.10 23 246 3.1E-31 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 119 610 3.7E-59 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 Pfam PF00702 haloacid dehalogenase-like hydrolase 343 554 1.6E-35 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 Pfam PF00122 E1-E2 ATPase 145 324 3.6E-47 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 Gene3D G3DSA:3.40.1110.10 358 468 1.9E-22 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 SUPERFAMILY SSF81665 246 339 2.75E-7 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 SUPERFAMILY SSF81665 96 148 2.75E-7 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 Gene3D G3DSA:3.40.50.1000 469 607 1.7E-28 T 28-03-2018 IPR023214 HAD-like domain CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 347 353 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 560 5.8E-18 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 195 209 5.8E-18 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 488 498 5.8E-18 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 476 5.8E-18 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 5.8E-18 T 28-03-2018 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 SUPERFAMILY SSF56784 404 640 9.42E-42 T 28-03-2018 IPR023214 HAD-like domain CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 SUPERFAMILY SSF56784 343 363 9.42E-42 T 28-03-2018 IPR023214 HAD-like domain CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00941 Cadmium-transporting ATPase signature 129 149 1.2E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00941 Cadmium-transporting ATPase signature 230 244 1.2E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS08050 3ddb9ed786e8ec2663908a80727743df 657 PRINTS PR00941 Cadmium-transporting ATPase signature 211 227 1.2E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 Gene3D G3DSA:3.40.50.300 40 275 3.6E-15 T 28-03-2018 CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 10 574 1.5E-201 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 SMART SM00382 368 550 0.0064 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 SMART SM00382 76 254 0.46 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 Gene3D G3DSA:3.40.50.300 341 526 4.6E-6 T 28-03-2018 CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 SUPERFAMILY SSF52540 27 268 7.45E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 SUPERFAMILY SSF52540 320 521 2.23E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 Pfam PF01580 FtsK/SpoIIIE family 361 449 4.9E-11 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS21165 85b634d3f614e49788b5fa99c3cd9819 591 Pfam PF01580 FtsK/SpoIIIE family 57 289 1.6E-43 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 577 5.6E-269 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Hamap MF_01953 Urease subunit alpha [ureC]. 2 577 55.848 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 SUPERFAMILY SSF51338 2 183 1.73E-56 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 SUPERFAMILY SSF51556 491 577 9.59E-183 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 SUPERFAMILY SSF51556 136 442 9.59E-183 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 ProSitePatterns PS00145 Urease active site. 324 340 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 SUPERFAMILY SSF51338 419 489 3.11E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Gene3D G3DSA:2.30.40.10 58 149 1.4E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 9.8E-53 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 2.1E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 2.1E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 411 426 2.1E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 437 450 2.1E-32 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Gene3D G3DSA:3.20.20.140 432 563 6.4E-43 T 28-03-2018 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Gene3D G3DSA:3.20.20.140 150 431 2.9E-155 T 28-03-2018 CP478_RS10060 2ef46c16cd8c693a3d8001da4612e5aa 577 Pfam PF01979 Amidohydrolase family 132 458 6.7E-69 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 Gene3D G3DSA:2.30.30.60 146 200 1.5E-8 T 28-03-2018 CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 Pfam PF00924 Mechanosensitive ion channel 89 292 5.3E-42 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 SUPERFAMILY SSF50182 131 196 5.56E-11 T 28-03-2018 IPR010920 LSM domain CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 Gene3D G3DSA:3.30.70.100 201 297 3.8E-8 T 28-03-2018 CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 SUPERFAMILY SSF82689 200 295 1.03E-7 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CP478_RS16990 4a4908ce93f1c814ac7e631d6546430a 308 SUPERFAMILY SSF82861 41 129 2.88E-6 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Gene3D G3DSA:4.10.80.40 536 590 1.1E-17 T 28-03-2018 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Gene3D G3DSA:3.50.50.60 303 417 4.0E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Pfam PF02910 Fumarate reductase flavoprotein C-term 456 590 1.9E-43 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 8 590 6.8E-257 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 SUPERFAMILY SSF51905 4 260 9.32E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 SUPERFAMILY SSF51905 359 433 9.32E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 PIRSF PIRSF000171 1 564 7.9E-44 T 28-03-2018 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 SUPERFAMILY SSF56425 237 355 6.73E-41 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Pfam PF00890 FAD binding domain 8 401 2.3E-110 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Gene3D G3DSA:3.50.50.60 4 302 7.7E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 SUPERFAMILY SSF46977 447 590 1.7E-45 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 5 590 0.0 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18180 cac110330a9d1c220afa5465ff622003 590 Gene3D G3DSA:1.20.58.100 426 535 3.5E-33 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01650 cc2f23ef3e8c87ea8eb6f80faf052abb 238 Pfam PF01569 PAP2 superfamily 92 204 1.4E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS01650 cc2f23ef3e8c87ea8eb6f80faf052abb 238 Gene3D G3DSA:1.20.144.10 12 219 2.3E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS01650 cc2f23ef3e8c87ea8eb6f80faf052abb 238 SMART SM00014 71 202 3.3E-29 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS01650 cc2f23ef3e8c87ea8eb6f80faf052abb 238 SUPERFAMILY SSF48317 12 210 2.22E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CP478_RS10965 3fd1a0c2a8086492c81e5fd0c4e3d60b 164 Pfam PF07166 Protein of unknown function (DUF1398) 44 147 1.4E-9 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CP478_RS10965 3fd1a0c2a8086492c81e5fd0c4e3d60b 164 Gene3D G3DSA:3.30.1810.10 26 150 7.7E-27 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CP478_RS10965 3fd1a0c2a8086492c81e5fd0c4e3d60b 164 SUPERFAMILY SSF160419 35 147 5.49E-19 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 SUPERFAMILY SSF50249 681 812 1.96E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 76 290 2.5E-80 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 688 1172 33.985 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 PRINTS PR00982 Lysyl-tRNA synthetase signature 857 867 2.4E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 PRINTS PR00982 Lysyl-tRNA synthetase signature 920 937 2.4E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 PRINTS PR00982 Lysyl-tRNA synthetase signature 902 915 2.4E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 PRINTS PR00982 Lysyl-tRNA synthetase signature 1055 1071 2.4E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 PRINTS PR00982 Lysyl-tRNA synthetase signature 873 889 2.4E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 684 1171 6.3E-135 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Gene3D G3DSA:2.40.50.140 682 813 3.3E-24 T 28-03-2018 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Gene3D G3DSA:3.30.930.10 814 1169 3.6E-82 T 28-03-2018 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 309 607 1.4E-102 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 SUPERFAMILY SSF55681 820 1169 1.1E-94 T 28-03-2018 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Pfam PF00152 tRNA synthetases class II (D, K and N) 822 1168 6.9E-67 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Gene3D G3DSA:3.40.630.30 417 557 2.4E-5 T 28-03-2018 CP478_RS08980 abdc49efadb96c1b12a6b089a000719c 1172 Pfam PF01336 OB-fold nucleic acid binding domain 726 804 3.9E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Pfam PF08278 DNA primase DnaG DnaB-binding 487 614 1.3E-30 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Hamap MF_00974 DNA primase [dnaG]. 4 620 25.607 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Gene3D G3DSA:1.20.50.20 375 428 6.1E-21 T 28-03-2018 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 SMART SM00400 37 91 6.3E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 SMART SM00766 486 615 3.3E-37 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 PIRSF PIRSF002811 2 626 1.3E-138 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Pfam PF10410 DnaB-helicase binding domain of primase 376 429 4.1E-18 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 1.1E-111 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Gene3D G3DSA:1.10.860.10 470 619 1.3E-40 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 SUPERFAMILY SSF56731 117 432 7.72E-93 T 28-03-2018 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Gene3D G3DSA:3.40.1360.10 244 374 2.7E-26 T 28-03-2018 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Gene3D G3DSA:3.90.980.10 110 243 4.3E-39 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Pfam PF13662 Toprim domain 263 337 7.5E-13 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 SUPERFAMILY SSF57783 4 100 8.67E-32 T 28-03-2018 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 SMART SM00493 262 340 1.8E-13 T 28-03-2018 IPR006171 TOPRIM domain CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Pfam PF01807 CHC2 zinc finger 6 100 1.8E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 1.2E-35 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CP478_RS12785 b2f501e76fc9137babd947ad11565f4c 639 Gene3D G3DSA:3.90.580.10 1 103 1.8E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 Gene3D G3DSA:1.20.1410.10 454 698 7.1E-4 T 28-03-2018 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 TIGRFAM TIGR00833 actII: transport protein 1 967 4.0E-280 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 Pfam PF03176 MMPL family 30 357 1.3E-105 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 Pfam PF03176 MMPL family 635 967 3.2E-88 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 SUPERFAMILY SSF82866 126 332 2.22E-26 T 28-03-2018 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 Gene3D G3DSA:1.20.1640.10 126 339 1.6E-25 T 28-03-2018 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 SUPERFAMILY SSF82866 742 967 1.24E-24 T 28-03-2018 CP478_RS06485 d3c9e7f2a759b18f26228de0245c6823 1002 Gene3D G3DSA:1.20.1640.10 741 963 2.1E-20 T 28-03-2018 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 Gene3D G3DSA:3.40.50.620 2 306 1.2E-83 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 SUPERFAMILY SSF47323 321 462 4.97E-29 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 7 461 2.3E-127 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 21 314 3.0E-126 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 SMART SM00840 342 403 3.5E-10 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 7 464 34.192 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 1.1E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 1.1E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 30 41 1.1E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 1.1E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 Gene3D G3DSA:1.20.120.640 307 394 1.3E-12 T 28-03-2018 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 Pfam PF09190 DALR domain 342 394 1.4E-6 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CP478_RS19565 301aebe000fb3db68dbbb0f5f3778878 469 SUPERFAMILY SSF52374 11 314 1.18E-88 T 28-03-2018 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 SUPERFAMILY SSF51395 13 196 4.95E-80 T 28-03-2018 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 SUPERFAMILY SSF51395 226 378 4.95E-80 T 28-03-2018 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 TIGRFAM TIGR03966 actino_HemFlav: heme/flavin dehydrogenase, mycofactocin system 3 385 1.1E-214 T 28-03-2018 IPR023989 Heme/flavin dehydrogenase, Rv0694 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 Pfam PF01070 FMN-dependent dehydrogenase 16 376 4.4E-108 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 PIRSF PIRSF000138 5 383 1.1E-103 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CP478_RS03755 2b2a946fd7efe6053991a7969d5cef5c 396 Gene3D G3DSA:3.20.20.70 7 382 6.0E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS12130 7234170111bf7866606d367d45e6615c 364 Gene3D G3DSA:3.90.1150.10 248 359 1.6E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS12130 7234170111bf7866606d367d45e6615c 364 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 217 230 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CP478_RS12130 7234170111bf7866606d367d45e6615c 364 Pfam PF00155 Aminotransferase class I and II 42 332 2.8E-23 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS12130 7234170111bf7866606d367d45e6615c 364 Gene3D G3DSA:3.40.640.10 54 247 1.8E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS12130 7234170111bf7866606d367d45e6615c 364 SUPERFAMILY SSF53383 38 354 2.07E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 ProSitePatterns PS00397 Site-specific recombinases active site. 55 63 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 Gene3D G3DSA:1.10.1660.20 1 42 9.6E-6 T 28-03-2018 CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 SMART SM00857 52 187 4.2E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 Pfam PF00239 Resolvase, N terminal domain 53 189 3.9E-17 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 Gene3D G3DSA:3.40.50.1390 46 192 1.2E-21 T 28-03-2018 CP478_RS15285 a1aa2a14138777fa3a29b9840596e1fe 193 SUPERFAMILY SSF53041 51 182 2.75E-20 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS00110 6c6b5305865fb0b64ed15e3d1c22f9f0 155 SMART SM00240 82 132 1.5E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS00110 6c6b5305865fb0b64ed15e3d1c22f9f0 155 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 66 154 3.0E-16 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CP478_RS00110 6c6b5305865fb0b64ed15e3d1c22f9f0 155 Gene3D G3DSA:2.60.200.20 52 154 1.6E-21 T 28-03-2018 CP478_RS00110 6c6b5305865fb0b64ed15e3d1c22f9f0 155 SUPERFAMILY SSF49879 58 153 9.95E-24 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS17700 a19f79d4df070bceac4beab74971c691 252 Gene3D G3DSA:3.90.1680.10 1 250 4.5E-74 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CP478_RS17700 a19f79d4df070bceac4beab74971c691 252 SUPERFAMILY SSF143081 2 241 1.24E-65 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CP478_RS17700 a19f79d4df070bceac4beab74971c691 252 Pfam PF02586 SOS response associated peptidase (SRAP) 1 231 5.0E-65 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CP478_RS15715 367e239789fb9f2ab62d00ebc6405cbb 695 Gene3D G3DSA:2.60.120.260 567 694 9.6E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS15715 367e239789fb9f2ab62d00ebc6405cbb 695 SUPERFAMILY SSF52833 410 544 8.75E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS15715 367e239789fb9f2ab62d00ebc6405cbb 695 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 122 338 8.5E-21 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CP478_RS15715 367e239789fb9f2ab62d00ebc6405cbb 695 Pfam PF00578 AhpC/TSA family 412 522 3.2E-12 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS15715 367e239789fb9f2ab62d00ebc6405cbb 695 Gene3D G3DSA:3.40.30.10 365 562 4.1E-24 T 28-03-2018 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Pfam PF01926 50S ribosome-binding GTPase 5 115 2.4E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 SUPERFAMILY SSF81271 273 357 1.53E-34 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 SUPERFAMILY SSF52540 4 295 3.17E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 357 42.526 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 PIRSF PIRSF006641 1 357 1.4E-136 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.3E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Gene3D G3DSA:1.10.150.300 110 196 7.5E-21 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Pfam PF06071 Protein of unknown function (DUF933) 273 356 4.0E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Gene3D G3DSA:3.10.20.30 257 356 2.5E-44 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 357 2.4E-128 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CP478_RS06095 e3483f45fb6f696cffdd824d36eb1a64 357 Gene3D G3DSA:3.40.50.300 2 80 4.5E-9 T 28-03-2018 CP478_RS14920 d8c35502af2e154a081619438af79793 397 Pfam PF03741 Integral membrane protein TerC family 69 276 2.7E-43 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CP478_RS14920 d8c35502af2e154a081619438af79793 397 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 322 3.6E-93 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 SUPERFAMILY SSF52540 153 311 1.87E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 Gene3D G3DSA:3.40.50.620 2 155 1.3E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 TIGRFAM TIGR01526 nadR_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 307 1.5E-132 T 28-03-2018 IPR006417 Nicotinamide-nucleotide adenylyltransferase GO:0003677|GO:0006355|GO:0006810|GO:0019363 KEGG: 00760+2.7.7.1+2.7.1.22 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 Pfam PF13521 AAA domain 154 307 1.4E-28 T 28-03-2018 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 Gene3D G3DSA:3.40.50.300 156 310 6.4E-10 T 28-03-2018 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 1.4E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 SUPERFAMILY SSF52374 4 145 6.95E-13 T 28-03-2018 CP478_RS01150 530d55ecd2b4fd5f439a460baeef5f29 323 PIRSF PIRSF004776 1 323 6.0E-132 T 28-03-2018 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 Gene3D G3DSA:3.90.1150.10 3 173 2.5E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 Pfam PF00202 Aminotransferase class-III 38 445 2.0E-132 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 299 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 Gene3D G3DSA:3.40.640.10 196 332 2.8E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 24 448 7.0E-229 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 PIRSF PIRSF000521 2 144 4.9E-9 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 PIRSF PIRSF000521 137 449 4.5E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 SUPERFAMILY SSF53383 38 448 7.5E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS14190 c53406b5814797f60a42243f3fe46bc2 449 Gene3D G3DSA:3.90.1150.10 333 449 7.0E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS02025 1be457f654bb822f0ccee990928ed229 183 Pfam PF00588 SpoU rRNA Methylase family 34 170 1.9E-22 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CP478_RS02025 1be457f654bb822f0ccee990928ed229 183 SUPERFAMILY SSF75217 18 177 4.38E-36 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS02025 1be457f654bb822f0ccee990928ed229 183 Gene3D G3DSA:3.40.1280.10 18 182 4.5E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Pfam PF00289 Biotin carboxylase, N-terminal domain 12 120 4.7E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Gene3D G3DSA:3.30.470.20 214 458 6.2E-93 T 28-03-2018 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Gene3D G3DSA:3.40.50.20 11 141 7.8E-48 T 28-03-2018 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Pfam PF02785 Biotin carboxylase C-terminal domain 345 455 7.9E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Pfam PF00364 Biotin-requiring enzyme 534 599 2.3E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 SMART SM00878 345 455 1.2E-60 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Gene3D G3DSA:3.30.1490.20 144 213 5.2E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 SUPERFAMILY SSF51246 339 459 1.99E-38 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 SUPERFAMILY SSF51230 527 599 3.27E-20 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 556 573 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Gene3D G3DSA:2.40.50.100 531 600 9.1E-18 T 28-03-2018 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 SUPERFAMILY SSF52440 9 123 2.81E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 125 333 5.7E-78 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS18005 f0fe4c5b54736fb1d06a444514349622 600 SUPERFAMILY SSF56059 125 335 4.07E-57 T 28-03-2018 CP478_RS05655 944f341978ba2b99f0619428e31482e3 189 PIRSF PIRSF001296 1 189 3.3E-76 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CP478_RS05655 944f341978ba2b99f0619428e31482e3 189 Pfam PF02669 K+-transporting ATPase, c chain 6 188 1.3E-73 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CP478_RS05655 944f341978ba2b99f0619428e31482e3 189 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 189 3.8E-98 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CP478_RS05655 944f341978ba2b99f0619428e31482e3 189 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 35.342 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CP478_RS00745 0c86a0aa43fa5cd13692e5d51802d63e 182 SUPERFAMILY SSF55068 3 162 1.02E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CP478_RS00745 0c86a0aa43fa5cd13692e5d51802d63e 182 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 4 159 33.871 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CP478_RS00745 0c86a0aa43fa5cd13692e5d51802d63e 182 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 153 7.2E-50 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CP478_RS00745 0c86a0aa43fa5cd13692e5d51802d63e 182 Gene3D G3DSA:3.30.1060.10 3 170 1.5E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CP478_RS00745 0c86a0aa43fa5cd13692e5d51802d63e 182 Pfam PF01625 Peptide methionine sulfoxide reductase 6 153 2.0E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Gene3D G3DSA:1.20.970.10 3 72 8.0E-21 T 28-03-2018 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 340 411 2.4E-19 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 SMART SM00941 338 412 1.8E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 SUPERFAMILY SSF47648 7 74 1.96E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Gene3D G3DSA:3.40.1030.10 73 329 1.4E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 SUPERFAMILY SSF54680 325 426 2.49E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 115 130 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 411 8.3E-161 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 71 7.4E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Pfam PF00591 Glycosyl transferase family, a/b domain 83 291 1.5E-32 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 PIRSF PIRSF000478 5 427 1.1E-154 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 SUPERFAMILY SSF52418 75 319 3.4E-79 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS18160 bc609d48c0bc81f48f151c6411dd02ae 427 Gene3D G3DSA:3.90.1170.30 330 417 2.1E-23 T 28-03-2018 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 Pfam PF00501 AMP-binding enzyme 455 861 4.5E-28 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 Pfam PF00561 alpha/beta hydrolase fold 125 340 1.1E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 Gene3D G3DSA:3.40.50.980 446 612 2.5E-19 T 28-03-2018 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 Gene3D G3DSA:3.40.50.980 613 781 3.9E-16 T 28-03-2018 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 SUPERFAMILY SSF56801 443 960 8.77E-45 T 28-03-2018 CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 SUPERFAMILY SSF53474 53 360 3.0E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09190 9abb26dfb816e42b7aa49574d612b07b 999 Gene3D G3DSA:3.40.50.1820 29 360 2.6E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF52777 1222 1460 3.11E-14 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:1.10.1200.10 971 1038 2.5E-14 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 ProSitePatterns PS00455 Putative AMP-binding domain signature. 603 614 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF52777 1045 1232 1.56E-22 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF52777 200 448 2.89E-42 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Pfam PF00668 Condensation domain 1068 1345 7.4E-16 T 28-03-2018 IPR001242 Condensation domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Pfam PF00668 Condensation domain 17 455 2.4E-60 T 28-03-2018 IPR001242 Condensation domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Pfam PF00501 AMP-binding enzyme 477 862 1.3E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Pfam PF00550 Phosphopantetheine attachment site 970 1031 1.8E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:3.40.50.980 610 772 1.1E-28 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF47336 961 1032 5.61E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:3.30.559.10 11 216 1.8E-37 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Pfam PF13193 AMP-binding enzyme C-terminal domain 870 943 3.6E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SMART SM00823 Phosphopantetheine attachment site 966 1035 0.0017 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF56801 440 978 3.53E-129 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 498 885 4.6E-103 T 28-03-2018 IPR010071 Amino acid adenylation domain CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 SUPERFAMILY SSF52777 14 214 3.78E-40 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:3.30.300.30 857 970 1.9E-31 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:2.30.38.10 775 855 4.0E-23 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:3.30.559.10 1039 1221 8.4E-18 T 28-03-2018 CP478_RS12970 47cf49b24ea23d5f8c9b581828638918 1461 Gene3D G3DSA:3.40.50.980 468 609 3.3E-35 T 28-03-2018 CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 Gene3D G3DSA:3.30.1120.10 495 586 2.4E-12 T 28-03-2018 CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 Gene3D G3DSA:2.60.120.200 600 767 8.1E-7 T 28-03-2018 CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 SUPERFAMILY SSF53649 37 575 1.17E-128 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 ProSitePatterns PS00523 Sulfatases signature 1. 81 93 - T 28-03-2018 IPR024607 Sulfatase, conserved site CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 Pfam PF00884 Sulfatase 37 466 1.9E-97 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 ProSitePatterns PS00149 Sulfatases signature 2. 133 143 - T 28-03-2018 IPR024607 Sulfatase, conserved site CP478_RS03855 e823ef34314662213de43159d91a9dc8 787 Gene3D G3DSA:3.40.720.10 34 494 3.7E-96 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 4 239 2.2E-104 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 Hamap MF_00564 Ribonuclease PH [rph]. 3 240 45.518 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 SUPERFAMILY SSF54211 3 184 3.14E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 ProSitePatterns PS01277 Ribonuclease PH signature. 118 131 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 Pfam PF03725 3' exoribonuclease family, domain 2 161 225 1.9E-9 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 SUPERFAMILY SSF55666 157 247 1.26E-20 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 Gene3D G3DSA:3.30.230.70 1 241 1.8E-56 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS07345 846a879c6a7cae7781434665c0f92d1a 259 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 7.6E-25 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 SUPERFAMILY SSF51338 7 62 1.96E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 SUPERFAMILY SSF51338 491 533 1.96E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 Gene3D G3DSA:3.20.20.140 71 471 1.6E-39 T 28-03-2018 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 Gene3D G3DSA:2.30.40.10 3 70 1.1E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 SUPERFAMILY SSF51556 200 492 2.04E-22 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 SUPERFAMILY SSF51556 61 93 2.04E-22 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 Gene3D G3DSA:3.20.20.140 472 533 0.015 T 28-03-2018 CP478_RS02955 7717969aaaeee97b36c3ff1b621345b1 534 Pfam PF07969 Amidohydrolase family 50 532 2.5E-79 T 28-03-2018 IPR013108 Amidohydrolase 3 CP478_RS05615 8d2c8752b9b72b27f39982ce8201f6a6 319 Gene3D G3DSA:3.30.420.150 128 317 1.3E-52 T 28-03-2018 CP478_RS05615 8d2c8752b9b72b27f39982ce8201f6a6 319 SUPERFAMILY SSF53067 140 317 5.44E-36 T 28-03-2018 CP478_RS05615 8d2c8752b9b72b27f39982ce8201f6a6 319 Pfam PF02541 Ppx/GppA phosphatase family 20 316 1.4E-91 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CP478_RS05615 8d2c8752b9b72b27f39982ce8201f6a6 319 Gene3D G3DSA:3.30.420.40 2 127 1.7E-42 T 28-03-2018 CP478_RS05615 8d2c8752b9b72b27f39982ce8201f6a6 319 SUPERFAMILY SSF53067 5 134 1.3E-28 T 28-03-2018 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Gene3D G3DSA:3.40.50.980 33 194 1.4E-31 T 28-03-2018 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Gene3D G3DSA:2.30.38.10 350 431 3.3E-18 T 28-03-2018 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Gene3D G3DSA:3.30.300.30 433 537 8.4E-24 T 28-03-2018 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 525 8.8E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Pfam PF00501 AMP-binding enzyme 42 438 2.3E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 SUPERFAMILY SSF56801 40 535 3.14E-125 T 28-03-2018 CP478_RS01160 93f605bb0180368886ad8f7271e366ba 537 Gene3D G3DSA:3.40.50.980 195 349 1.2E-36 T 28-03-2018 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Gene3D G3DSA:3.40.1190.10 104 329 2.5E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Pfam PF01225 Mur ligase family, catalytic domain 13 115 7.1E-23 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Gene3D G3DSA:3.40.50.720 2 103 1.6E-13 T 28-03-2018 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 10 480 38.549 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Pfam PF08245 Mur ligase middle domain 120 309 4.8E-26 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 SUPERFAMILY SSF51984 11 102 7.72E-20 T 28-03-2018 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 421 3.3E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 474 7.4E-163 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 SUPERFAMILY SSF53244 328 477 2.38E-42 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 SUPERFAMILY SSF53623 102 327 1.23E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11710 2d34b8c34f7145313438b2c0d3ecc3d6 494 Gene3D G3DSA:3.90.190.20 330 480 7.3E-39 T 28-03-2018 CP478_RS18885 f9140d71b5b4b106e3c24f2a0afe5776 262 ProSitePatterns PS00155 Cutinase, serine active site. 115 127 - T 28-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CP478_RS18885 f9140d71b5b4b106e3c24f2a0afe5776 262 Gene3D G3DSA:3.40.50.1820 39 230 6.3E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18885 f9140d71b5b4b106e3c24f2a0afe5776 262 SMART SM01110 42 226 8.6E-88 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS18885 f9140d71b5b4b106e3c24f2a0afe5776 262 SUPERFAMILY SSF53474 35 227 2.34E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18885 f9140d71b5b4b106e3c24f2a0afe5776 262 Pfam PF01083 Cutinase 44 226 6.6E-56 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS10705 339428beb1f99a2f37de030df18b7ae0 425 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 150 411 1.1E-96 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS10705 339428beb1f99a2f37de030df18b7ae0 425 Gene3D G3DSA:1.10.287.1060 167 249 4.2E-5 T 28-03-2018 CP478_RS10705 339428beb1f99a2f37de030df18b7ae0 425 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 304 9.1E-83 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10705 339428beb1f99a2f37de030df18b7ae0 425 Pfam PF02470 MlaD protein 42 121 5.1E-15 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS08325 482b2f60fafc06207e6ac5898255a63b 319 Pfam PF00535 Glycosyl transferase family 2 20 156 1.4E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS08325 482b2f60fafc06207e6ac5898255a63b 319 SUPERFAMILY SSF53448 17 244 1.97E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08325 482b2f60fafc06207e6ac5898255a63b 319 Gene3D G3DSA:3.90.550.10 5 262 1.0E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS00325 c1dd089f1dcaf594f1fd0e9301281d44 352 Pfam PF01661 Macro domain 18 131 2.6E-23 T 28-03-2018 IPR002589 Macro domain CP478_RS00325 c1dd089f1dcaf594f1fd0e9301281d44 352 SUPERFAMILY SSF52949 1 148 3.03E-44 T 28-03-2018 CP478_RS00325 c1dd089f1dcaf594f1fd0e9301281d44 352 Gene3D G3DSA:3.40.220.10 1 211 1.5E-37 T 28-03-2018 CP478_RS00325 c1dd089f1dcaf594f1fd0e9301281d44 352 SMART SM00506 1 132 2.1E-34 T 28-03-2018 IPR002589 Macro domain CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Gene3D G3DSA:3.40.50.300 1 36 3.5E-6 T 28-03-2018 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Gene3D G3DSA:3.40.50.300 37 80 0.0019 T 28-03-2018 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 ProSitePatterns PS00211 ABC transporters family signature. 843 857 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Gene3D G3DSA:3.40.50.300 623 961 2.0E-55 T 28-03-2018 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Gene3D G3DSA:1.20.1580.10 92 501 8.1E-89 T 28-03-2018 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 ProSitePatterns PS00211 ABC transporters family signature. 501 515 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Pfam PF00005 ABC transporter 637 873 1.0E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 SUPERFAMILY SSF52540 444 583 8.91E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 SUPERFAMILY SSF52540 11 205 8.91E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 953 23.11 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 938 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CP478_RS08965 f84d737fdd0073e92dd6b49f48d87279 972 SUPERFAMILY SSF52540 628 927 1.66E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 132 4.4E-24 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 SUPERFAMILY SSF46548 10 155 4.97E-40 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Gene3D G3DSA:3.50.50.60 334 404 0.016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Gene3D G3DSA:3.50.50.60 242 332 2.0E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.2E-23 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 PRINTS PR00419 Adrenodoxin reductase family signature 290 304 1.2E-23 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.2E-23 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.2E-23 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 477 1.5E-243 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Gene3D G3DSA:1.10.1060.10 7 144 4.0E-44 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 SUPERFAMILY SSF51971 143 404 8.83E-68 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 SUPERFAMILY SSF51971 371 471 2.24E-12 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Gene3D G3DSA:3.40.50.720 145 241 1.9E-21 T 28-03-2018 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Gene3D G3DSA:3.50.50.60 405 486 9.6E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21090 bc7c645c12bdcd353f24f500b243d37b 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 459 1.3E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS13865 68f6d016154b635a7445e93e828f67a9 139 SUPERFAMILY SSF88723 3 128 6.45E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13865 68f6d016154b635a7445e93e828f67a9 139 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 138 2.9E-47 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS13865 68f6d016154b635a7445e93e828f67a9 139 Pfam PF01850 PIN domain 4 128 1.3E-7 T 28-03-2018 IPR002716 PIN domain CP478_RS13865 68f6d016154b635a7445e93e828f67a9 139 Gene3D G3DSA:3.40.50.1010 1 134 3.4E-12 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13865 68f6d016154b635a7445e93e828f67a9 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 137 15.758 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS09960 117994b5ca0d2623c5b93f59c7d24e53 225 Gene3D G3DSA:1.10.1660.10 65 141 2.9E-14 T 28-03-2018 CP478_RS09960 117994b5ca0d2623c5b93f59c7d24e53 225 Pfam PF13411 MerR HTH family regulatory protein 69 134 8.3E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS09960 117994b5ca0d2623c5b93f59c7d24e53 225 SUPERFAMILY SSF46955 70 153 7.33E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS09960 117994b5ca0d2623c5b93f59c7d24e53 225 SMART SM00422 65 137 2.3E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS16350 e56916fb84cba823515bb689304a3676 163 SUPERFAMILY SSF50475 7 148 6.73E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS16350 e56916fb84cba823515bb689304a3676 163 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 100 3.1E-22 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS16350 e56916fb84cba823515bb689304a3676 163 PIRSF PIRSF004633 1 140 4.1E-6 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain CP478_RS16350 e56916fb84cba823515bb689304a3676 163 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 143 6.0E-37 T 28-03-2018 IPR019920 F420-binding domain, putative CP478_RS16350 e56916fb84cba823515bb689304a3676 163 Gene3D G3DSA:2.30.110.10 5 158 5.3E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 226 7.2E-87 T 28-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 226 34.981 T 28-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 SUPERFAMILY SSF56235 2 225 1.12E-21 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 Pfam PF13522 Glutamine amidotransferase domain 69 197 7.5E-14 T 28-03-2018 CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 Gene3D G3DSA:3.60.20.10 1 188 1.7E-22 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS20225 2600a52e3a9daa01650f448ef1090dfb 233 Gene3D G3DSA:3.60.20.10 189 227 0.22 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 22 374 4.4E-91 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 SUPERFAMILY SSF101790 286 375 3.92E-23 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 SUPERFAMILY SSF103025 21 293 1.43E-85 T 28-03-2018 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Gene3D G3DSA:2.40.30.110 294 379 6.3E-21 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Pfam PF01571 Aminomethyltransferase folate-binding domain 24 272 1.0E-81 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Hamap MF_00259 Aminomethyltransferase [gcvT]. 18 376 41.335 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 279 370 9.7E-21 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 PIRSF PIRSF006487 12 379 1.3E-80 T 28-03-2018 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Gene3D G3DSA:4.10.1250.10 250 292 1.1E-12 T 28-03-2018 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Gene3D G3DSA:3.30.1360.120 19 146 3.1E-29 T 28-03-2018 CP478_RS12015 2d49be908eb859e30a5bae8def0ac358 379 Gene3D G3DSA:3.30.1360.120 147 249 5.2E-22 T 28-03-2018 CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 PIRSF PIRSF000535 11 321 1.6E-122 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 SUPERFAMILY SSF53613 14 307 7.79E-64 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 Pfam PF00294 pfkB family carbohydrate kinase 19 305 1.8E-56 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 Gene3D G3DSA:2.20.150.10 21 55 6.1E-10 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 48 72 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 14 312 6.6E-79 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CP478_RS11075 45c0a064175c44929a779d9510eb502d 339 Gene3D G3DSA:3.40.1190.20 56 319 7.1E-39 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 SUPERFAMILY SSF46689 2 82 8.72E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15905 1881b69994f90ff61c90a41180cf678c 195 Gene3D G3DSA:1.10.357.10 2 194 1.4E-21 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:3.40.50.300 391 576 4.0E-36 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 SUPERFAMILY SSF52540 397 563 1.11E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 PRINTS PR00315 GTP-binding elongation factor signature 400 413 6.2E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 PRINTS PR00315 GTP-binding elongation factor signature 468 479 6.2E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 PRINTS PR00315 GTP-binding elongation factor signature 452 462 6.2E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 PRINTS PR00315 GTP-binding elongation factor signature 504 513 6.2E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Pfam PF00009 Elongation factor Tu GTP binding domain 401 561 3.7E-32 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 308 899 3.9E-221 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 SUPERFAMILY SSF50447 574 657 4.91E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 399 557 2.1E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 5 53 1.3E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 316 362 4.4E-6 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:3.30.56.50 316 356 0.0078 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:3.30.56.50 7 48 3.9E-12 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 ProSitePatterns PS01176 Initiation factor 2 signature. 853 875 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:2.40.30.10 577 703 4.4E-34 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:2.40.30.10 802 900 2.2E-25 T 28-03-2018 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Pfam PF11987 Translation-initiation factor 2 689 791 2.0E-32 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Gene3D G3DSA:3.40.50.10050 704 780 1.4E-23 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 SUPERFAMILY SSF52156 681 808 1.57E-34 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 5 899 16.571 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CP478_RS15525 07ee604d69098b45a3b7d95ec7b388ab 900 SUPERFAMILY SSF50447 802 899 2.55E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 Gene3D G3DSA:3.40.50.200 47 389 6.0E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 SUPERFAMILY SSF52743 77 385 5.11E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 94 104 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 129 139 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 327 337 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 Pfam PF00082 Subtilase family 89 376 5.1E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 79 448 5.0E-126 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 PRINTS PR00723 Subtilisin serine protease family (S8) signature 326 342 7.3E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 PRINTS PR00723 Subtilisin serine protease family (S8) signature 125 138 7.3E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS18875 05fe58d6e38307f19b55196d74a2037c 455 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 108 7.3E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 Gene3D G3DSA:3.90.1150.10 263 371 2.2E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 229 238 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 17 364 2.3E-103 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 Gene3D G3DSA:3.40.640.10 56 262 2.0E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 SUPERFAMILY SSF53383 33 365 1.53E-69 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 Pfam PF00155 Aminotransferase class I and II 34 355 2.9E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS08755 3b88ac7b2f0f5590d1e29b1a7ed8ec47 380 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 14 366 52.15 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 Pfam PF00581 Rhodanese-like domain 164 279 7.9E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 Pfam PF00581 Rhodanese-like domain 22 131 4.5E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 SUPERFAMILY SSF52821 14 152 2.75E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 Gene3D G3DSA:3.40.250.10 157 293 8.1E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 SMART SM00450 21 135 8.3E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 SMART SM00450 158 283 2.3E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 Gene3D G3DSA:3.40.250.10 12 154 3.6E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 ProSitePatterns PS00683 Rhodanese C-terminal signature. 267 277 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 ProSitePatterns PS00380 Rhodanese signature 1. 47 58 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS17995 5935dfbd5b9918c5590376537e7d0977 297 SUPERFAMILY SSF52821 163 287 9.95E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS06010 4a753dfc0db8b88ba16384b98103c788 275 PIRSF PIRSF000346 1 272 9.8E-80 T 28-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CP478_RS06010 4a753dfc0db8b88ba16384b98103c788 275 Gene3D G3DSA:1.10.620.20 1 271 1.2E-60 T 28-03-2018 CP478_RS06010 4a753dfc0db8b88ba16384b98103c788 275 SUPERFAMILY SSF47240 1 271 1.83E-68 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS06010 4a753dfc0db8b88ba16384b98103c788 275 Pfam PF03405 Fatty acid desaturase 13 264 1.8E-34 T 28-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CP478_RS08655 da765560a060ebb699b80733bb9acddb 131 SUPERFAMILY SSF46565 96 130 9.68E-5 T 28-03-2018 IPR001623 DnaJ domain CP478_RS17040 e55acd7f577b77b9795da903779287a7 176 SUPERFAMILY SSF53927 16 166 1.77E-25 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS17040 e55acd7f577b77b9795da903779287a7 176 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 22 113 5.3E-15 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CP478_RS17040 e55acd7f577b77b9795da903779287a7 176 Gene3D G3DSA:3.40.140.10 13 169 3.1E-20 T 28-03-2018 CP478_RS18365 f6d4fe070cbb1fe6a185bd1bf58fd852 136 Pfam PF01565 FAD binding domain 56 104 1.8E-6 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS18365 f6d4fe070cbb1fe6a185bd1bf58fd852 136 Gene3D G3DSA:3.30.43.10 54 127 1.7E-7 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS18365 f6d4fe070cbb1fe6a185bd1bf58fd852 136 SUPERFAMILY SSF56176 56 106 1.92E-6 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS21385 987867196aa60e869b89f424a2180065 116 Gene3D G3DSA:3.40.30.10 1 115 1.4E-34 T 28-03-2018 CP478_RS21385 987867196aa60e869b89f424a2180065 116 TIGRFAM TIGR01068 thioredoxin: thioredoxin 13 110 8.5E-40 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CP478_RS21385 987867196aa60e869b89f424a2180065 116 SUPERFAMILY SSF52833 8 112 1.33E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS21385 987867196aa60e869b89f424a2180065 116 Pfam PF00085 Thioredoxin 10 108 4.0E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CP478_RS21385 987867196aa60e869b89f424a2180065 116 PRINTS PR00421 Thioredoxin family signature 28 36 1.1E-8 T 28-03-2018 CP478_RS21385 987867196aa60e869b89f424a2180065 116 PRINTS PR00421 Thioredoxin family signature 36 45 1.1E-8 T 28-03-2018 CP478_RS21385 987867196aa60e869b89f424a2180065 116 PRINTS PR00421 Thioredoxin family signature 76 87 1.1E-8 T 28-03-2018 CP478_RS21385 987867196aa60e869b89f424a2180065 116 PIRSF PIRSF000077 6 112 5.0E-45 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CP478_RS21385 987867196aa60e869b89f424a2180065 116 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CP478_RS08405 8beeddff5f003b3cd55afafa1f5ea499 375 Gene3D G3DSA:3.20.20.70 1 371 5.7E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08405 8beeddff5f003b3cd55afafa1f5ea499 375 SUPERFAMILY SSF51412 1 70 1.53E-48 T 28-03-2018 CP478_RS08405 8beeddff5f003b3cd55afafa1f5ea499 375 SUPERFAMILY SSF51412 120 367 1.53E-48 T 28-03-2018 CP478_RS08405 8beeddff5f003b3cd55afafa1f5ea499 375 Pfam PF03060 Nitronate monooxygenase 23 361 3.7E-56 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:2.70.150.10 618 865 1.8E-31 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 725 985 2.7E-29 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1196 1311 4.4E-23 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1228 1244 2.1E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1077 1095 2.1E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1200 1216 2.1E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1260 1285 2.1E-13 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:1.20.1110.10 1254 1472 1.3E-28 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF81660 975 1134 4.05E-6 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1252 1264 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 803 817 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 963 977 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1126 1137 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1228 1247 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1148 1158 3.6E-25 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Pfam PF00702 haloacid dehalogenase-like hydrolase 960 1241 1.8E-21 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF81653 765 864 9.42E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Pfam PF00122 E1-E2 ATPase 754 941 1.5E-44 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:3.40.50.1000 1132 1253 4.6E-21 T 28-03-2018 IPR023214 HAD-like domain CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:3.30.70.100 77 146 0.006 T 28-03-2018 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:3.40.1110.10 922 1131 5.4E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF81665 864 957 7.72E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF81665 627 751 7.72E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF81665 1278 1462 7.72E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Gene3D G3DSA:3.40.50.1000 342 570 0.2 T 28-03-2018 IPR023214 HAD-like domain CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 Pfam PF00689 Cation transporting ATPase, C-terminus 1313 1461 2.0E-15 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF56784 961 981 5.34E-39 T 28-03-2018 IPR023214 HAD-like domain CP478_RS02265 19e2f7af3d4d2f500df35a4f064e41f7 1539 SUPERFAMILY SSF56784 1074 1333 5.34E-39 T 28-03-2018 IPR023214 HAD-like domain CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 SMART SM00382 349 520 1.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 486 1.2E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 42 593 1.4E-237 T 28-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 Gene3D G3DSA:3.40.50.300 286 486 8.9E-19 T 28-03-2018 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 SUPERFAMILY SSF52540 314 579 7.92E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 458 475 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 352 367 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 404 423 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 312 326 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 390 404 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 437 449 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 545 557 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 PRINTS PR00819 CbxX/CfqX superfamily signature 475 494 7.1E-33 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 Gene3D G3DSA:1.25.40.10 164 267 5.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 SUPERFAMILY SSF48452 34 58 2.39E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 SUPERFAMILY SSF48452 118 256 2.39E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS09790 89cda2cc8d6118ddc6266134352cf5b1 610 Gene3D G3DSA:1.25.40.10 4 163 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 56 69 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 SUPERFAMILY SSF51366 10 256 1.26E-77 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 Pfam PF00290 Tryptophan synthase alpha chain 16 249 1.9E-68 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 Gene3D G3DSA:3.20.20.70 10 269 3.6E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 22 263 32.002 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS08820 6fd0e3900d3ddea1d329d09b0479f5c7 270 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 16 251 7.4E-62 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CP478_RS02555 64ff1f712bc53eebbf08cb5cc2c3dbf0 348 Pfam PF11209 Protein of unknown function (DUF2993) 130 326 6.6E-17 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Gene3D G3DSA:3.30.43.10 11 87 1.1E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 230 365 1.0E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Gene3D G3DSA:3.30.465.10 88 242 1.5E-46 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Gene3D G3DSA:3.90.78.10 249 369 4.2E-37 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 365 1.7E-47 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 SUPERFAMILY SSF56176 20 202 8.72E-33 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 369 73.813 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 Pfam PF01565 FAD binding domain 34 167 5.1E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS02570 bf1aac2183b3d3e131fc02a03e4d5628 369 SUPERFAMILY SSF56194 226 367 1.05E-34 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS15550 3b55a51e83440b694282eaa2ca29d9d0 162 SUPERFAMILY SSF47240 19 158 1.07E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS15550 3b55a51e83440b694282eaa2ca29d9d0 162 Pfam PF14530 Domain of unknown function (DUF4439) 25 161 2.0E-44 T 28-03-2018 IPR029447 Domain of unknown function DUF4439 CP478_RS15550 3b55a51e83440b694282eaa2ca29d9d0 162 Gene3D G3DSA:1.20.1260.10 17 151 7.3E-17 T 28-03-2018 IPR012347 Ferritin-related CP478_RS15105 7c69631ade47f97f632285c8fe5ce5fd 138 SUPERFAMILY SSF88723 4 125 1.88E-12 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15105 7c69631ade47f97f632285c8fe5ce5fd 138 Gene3D G3DSA:3.40.50.1010 1 138 7.7E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15105 7c69631ade47f97f632285c8fe5ce5fd 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 128 13.994 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS15105 7c69631ade47f97f632285c8fe5ce5fd 138 Pfam PF01850 PIN domain 5 123 1.3E-12 T 28-03-2018 IPR002716 PIN domain CP478_RS10660 6829055a2e2f65abf3067c984ceefc15 83 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 2 80 3.0E-42 T 28-03-2018 IPR022789 Antitoxin ParD CP478_RS10660 6829055a2e2f65abf3067c984ceefc15 83 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 72 1.9E-27 T 28-03-2018 IPR022789 Antitoxin ParD CP478_RS10660 6829055a2e2f65abf3067c984ceefc15 83 SUPERFAMILY SSF47598 5 46 3.78E-8 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS10660 6829055a2e2f65abf3067c984ceefc15 83 Gene3D G3DSA:1.10.1220.10 6 45 7.1E-10 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS17390 0a542776ca9c8164accf88e8779f62f8 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 23 129 3.6E-27 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS17390 0a542776ca9c8164accf88e8779f62f8 131 Gene3D G3DSA:2.30.110.10 1 131 3.7E-30 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS17390 0a542776ca9c8164accf88e8779f62f8 131 Pfam PF04075 F420H(2)-dependent quinone reductase 2 129 1.9E-30 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Gene3D G3DSA:3.10.580.10 181 332 4.8E-35 T 28-03-2018 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 SUPERFAMILY SSF56176 340 430 2.67E-13 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Pfam PF03471 Transporter associated domain 341 406 6.9E-12 T 28-03-2018 IPR005170 Transporter-associated domain CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Pfam PF00571 CBS domain 202 255 5.0E-5 T 28-03-2018 IPR000644 CBS domain CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Pfam PF00571 CBS domain 269 323 1.1E-5 T 28-03-2018 IPR000644 CBS domain CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Pfam PF01595 Domain of unknown function DUF21 10 185 5.3E-33 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Gene3D G3DSA:1.20.1250.20 1 124 9.7E-6 T 28-03-2018 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 Gene3D G3DSA:3.30.465.10 333 417 1.8E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 SMART SM01091 339 422 3.8E-19 T 28-03-2018 IPR005170 Transporter-associated domain CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 SUPERFAMILY SSF54631 195 335 5.68E-34 T 28-03-2018 CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 SMART SM00116 209 258 1.6 T 28-03-2018 IPR000644 CBS domain CP478_RS12905 1d7f95775702cc1c71aaf025ce771494 435 SMART SM00116 275 323 5.0 T 28-03-2018 IPR000644 CBS domain CP478_RS04575 a51e3bc6fa87120c621d2b47d6fa2b7c 256 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 65 254 26.452 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CP478_RS04575 a51e3bc6fa87120c621d2b47d6fa2b7c 256 PIRSF PIRSF026671 37 251 7.6E-55 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CP478_RS04575 a51e3bc6fa87120c621d2b47d6fa2b7c 256 Gene3D G3DSA:3.30.1380.10 62 256 1.2E-39 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS04575 a51e3bc6fa87120c621d2b47d6fa2b7c 256 SUPERFAMILY SSF55166 64 248 3.14E-48 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS04575 a51e3bc6fa87120c621d2b47d6fa2b7c 256 Pfam PF01427 D-ala-D-ala dipeptidase 63 255 1.1E-79 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 SUPERFAMILY SSF52507 9 176 1.11E-53 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 191 384 3.2E-65 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 Gene3D G3DSA:3.40.50.10300 186 416 3.8E-64 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 Pfam PF02441 Flavoprotein 9 174 1.8E-36 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 9 409 6.1E-111 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 Gene3D G3DSA:3.40.50.1950 2 185 7.0E-49 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CP478_RS07625 968a01e1c0de4aef9958b8d9f0d6fe2a 418 SUPERFAMILY SSF102645 182 412 8.89E-64 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CP478_RS08485 faf478bc31a1fb3faf2620d334c5ee16 182 SUPERFAMILY SSF56801 31 177 3.66E-30 T 28-03-2018 CP478_RS08485 faf478bc31a1fb3faf2620d334c5ee16 182 Gene3D G3DSA:3.40.50.980 45 181 8.7E-29 T 28-03-2018 CP478_RS08485 faf478bc31a1fb3faf2620d334c5ee16 182 Pfam PF00501 AMP-binding enzyme 53 178 1.3E-24 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 163 289 3.1E-8 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 Gene3D G3DSA:1.20.120.20 136 197 5.7E-4 T 28-03-2018 CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 Gene3D G3DSA:1.10.287.1060 198 306 0.0043 T 28-03-2018 CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 302 2.2E-86 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 Pfam PF02470 MlaD protein 39 113 3.3E-13 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS19120 ebadb94581697a85b6727acba8e245db 451 SUPERFAMILY SSF58104 191 294 2.22E-5 T 28-03-2018 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 Gene3D G3DSA:3.10.25.10 208 312 2.9E-24 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 306 29.657 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 303 1.1E-20 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 Pfam PF00551 Formyl transferase 7 179 2.3E-31 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 SUPERFAMILY SSF53328 2 204 2.22E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 Gene3D G3DSA:3.40.50.170 1 206 7.9E-58 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 304 8.6E-65 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CP478_RS07700 c43d4104bfa537673485c7c4a389349b 312 SUPERFAMILY SSF50486 205 301 3.14E-24 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 Gene3D G3DSA:1.10.10.10 121 225 9.6E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 SUPERFAMILY SSF46894 127 218 1.08E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 3.9E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 SUPERFAMILY SSF52172 20 118 1.87E-6 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 Gene3D G3DSA:3.40.50.2300 20 120 4.2E-5 T 28-03-2018 CP478_RS04440 fa5e969d7f421b44a58872aa8b25ffca 255 SMART SM00862 145 219 4.2E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS15545 ee8fead179df0b59030da76d2a2f27aa 181 Gene3D G3DSA:1.20.1260.10 58 153 0.0012 T 28-03-2018 IPR012347 Ferritin-related CP478_RS03510 86cdd0fe87c3e9d8a66118aa47254e35 302 SUPERFAMILY SSF53067 1 301 4.32E-62 T 28-03-2018 CP478_RS03510 86cdd0fe87c3e9d8a66118aa47254e35 302 Gene3D G3DSA:3.30.420.40 2 123 3.5E-34 T 28-03-2018 CP478_RS03510 86cdd0fe87c3e9d8a66118aa47254e35 302 Gene3D G3DSA:3.30.420.40 124 302 1.6E-51 T 28-03-2018 CP478_RS03510 86cdd0fe87c3e9d8a66118aa47254e35 302 ProSitePatterns PS01125 ROK family signature. 134 161 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CP478_RS03510 86cdd0fe87c3e9d8a66118aa47254e35 302 Pfam PF00480 ROK family 4 299 5.6E-61 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 SUPERFAMILY SSF52540 5 244 2.74E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 Pfam PF00005 ABC transporter 22 163 2.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 SUPERFAMILY SSF50331 239 359 7.29E-17 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 Gene3D G3DSA:2.40.50.140 281 341 5.5E-11 T 28-03-2018 CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 Gene3D G3DSA:2.40.50.100 242 278 4.1E-6 T 28-03-2018 CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 SMART SM00382 30 213 1.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 Gene3D G3DSA:3.40.50.300 2 239 2.9E-67 T 28-03-2018 CP478_RS15490 0a8931f66a55f47a0878a2507ba64838 360 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 SUPERFAMILY SSF48452 100 260 2.8E-37 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 Gene3D G3DSA:1.10.10.10 1 95 1.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 SMART SM01043 101 246 2.0E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 SMART SM00862 15 93 6.3E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 93 5.4E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 Pfam PF03704 Bacterial transcriptional activator domain 101 246 1.6E-46 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 Gene3D G3DSA:1.25.40.10 98 257 3.3E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS17100 69546ad977b702e23c55c599ba33f79d 289 SUPERFAMILY SSF46894 3 93 3.4E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS19205 2d01a18654abc0e141d9db4ef7e83090 1489 SUPERFAMILY SSF140459 8 84 2.54E-24 T 28-03-2018 CP478_RS19205 2d01a18654abc0e141d9db4ef7e83090 1489 Pfam PF00934 PE family 1 93 1.8E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Gene3D G3DSA:1.10.10.10 1015 1085 2.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Gene3D G3DSA:3.40.50.300 182 331 2.3E-14 T 28-03-2018 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SMART SM00421 1024 1081 1.1E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Gene3D G3DSA:1.25.40.10 543 770 3.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Gene3D G3DSA:1.25.40.10 771 1004 2.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SUPERFAMILY SSF48452 638 806 6.07E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SUPERFAMILY SSF52540 185 447 3.41E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SUPERFAMILY SSF46894 1017 1083 5.1E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1041 1068 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SUPERFAMILY SSF48452 857 969 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00364 Disease resistance protein signature 379 393 4.6E-6 T 28-03-2018 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00364 Disease resistance protein signature 284 298 4.6E-6 T 28-03-2018 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00364 Disease resistance protein signature 216 231 4.6E-6 T 28-03-2018 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1057 1069 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1041 1057 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1027 1041 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Gene3D G3DSA:3.30.70.1230 5 173 8.8E-26 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 8 135 1.6E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 Pfam PF00196 Bacterial regulatory proteins, luxR family 1026 1080 4.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS02055 565fa629731a359032289acb18e9f9ab 1085 SUPERFAMILY SSF55073 6 179 1.73E-36 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SUPERFAMILY SSF49493 289 370 1.03E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Gene3D G3DSA:1.10.287.110 6 146 1.6E-28 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SUPERFAMILY SSF49493 143 199 5.1E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SUPERFAMILY SSF49493 243 291 5.1E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Pfam PF00684 DnaJ central domain 177 237 7.0E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Pfam PF01556 DnaJ C terminal domain 151 362 8.6E-37 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 379 3.8E-123 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Pfam PF00226 DnaJ domain 10 72 1.1E-24 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SUPERFAMILY SSF57938 164 240 1.44E-18 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SUPERFAMILY SSF46565 8 103 9.94E-29 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Gene3D G3DSA:2.10.230.10 174 226 1.3E-16 T 28-03-2018 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Gene3D G3DSA:2.60.260.20 227 284 8.6E-19 T 28-03-2018 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 SMART SM00271 9 67 1.7E-26 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Gene3D G3DSA:2.60.260.20 285 389 1.1E-25 T 28-03-2018 CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 PRINTS PR00625 DnaJ domain signature 67 86 4.0E-21 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 PRINTS PR00625 DnaJ domain signature 47 67 4.0E-21 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 PRINTS PR00625 DnaJ domain signature 12 30 4.0E-21 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 PRINTS PR00625 DnaJ domain signature 30 45 4.0E-21 T 28-03-2018 IPR001623 DnaJ domain CP478_RS01880 b1895da06184714c7799eb3c8aefa6df 395 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 391 37.536 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 3.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 SMART SM00448 2 112 2.1E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 SMART SM00862 148 224 3.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 Gene3D G3DSA:3.40.50.2300 2 121 3.4E-37 T 28-03-2018 CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 SUPERFAMILY SSF52172 3 185 1.57E-42 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS05625 d8d9b0d58a6c001ddef12ae8539ccb35 226 Gene3D G3DSA:1.10.10.10 122 226 2.0E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 SMART SM00729 27 235 5.0E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 Pfam PF04055 Radical SAM superfamily 33 196 1.4E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 Pfam PF13353 4Fe-4S single cluster domain 34 123 1.8E-5 T 28-03-2018 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 19 332 5.1E-102 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 33 44 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 18 359 38.409 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 Pfam PF06463 Molybdenum Cofactor Synthesis C 203 326 2.9E-34 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 Gene3D G3DSA:3.20.20.70 15 359 2.0E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS17015 fb4e79253a56682d9dffb4dc113e4b6d 359 SUPERFAMILY SSF102114 20 304 2.75E-66 T 28-03-2018 CP478_RS20390 afa4b7b19e04e3f1a8bb9c2823635d0b 352 Pfam PF10092 Uncharacterized protein conserved in bacteria (DUF2330) 29 246 1.5E-68 T 28-03-2018 IPR019283 Protein of unknown function DUF2330 CP478_RS03535 fa2d3831dedbab48a29d9cb2fdbe209b 359 SUPERFAMILY SSF52540 28 255 5.21E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03535 fa2d3831dedbab48a29d9cb2fdbe209b 359 Gene3D G3DSA:3.40.50.300 24 353 1.9E-56 T 28-03-2018 CP478_RS03535 fa2d3831dedbab48a29d9cb2fdbe209b 359 SMART SM00382 52 248 3.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS03535 fa2d3831dedbab48a29d9cb2fdbe209b 359 Pfam PF00005 ABC transporter 44 191 8.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS03535 fa2d3831dedbab48a29d9cb2fdbe209b 359 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 PIRSF PIRSF005303 13 323 3.3E-98 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 18 320 29.663 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 Gene3D G3DSA:3.90.650.10 161 323 2.0E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 SUPERFAMILY SSF56042 159 311 9.57E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 SUPERFAMILY SSF55326 15 153 5.58E-30 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 Gene3D G3DSA:3.30.1330.10 13 157 2.3E-30 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 19 323 4.5E-92 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 43 152 1.3E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS16280 3604b4d84ea077575245d30100cd51a6 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 166 250 1.5E-5 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Gene3D G3DSA:1.10.40.30 381 438 9.2E-27 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Gene3D G3DSA:1.10.275.10 7 112 2.6E-27 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Pfam PF00206 Lyase 16 306 6.9E-59 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 1.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 1.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 1.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 1.1E-24 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 459 38.791 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Gene3D G3DSA:1.20.200.10 113 380 6.6E-89 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 457 2.5E-190 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 SUPERFAMILY SSF48557 11 457 8.48E-129 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 Pfam PF14698 Argininosuccinate lyase C-terminal 369 436 3.3E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 3.4E-52 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 3.4E-52 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 3.4E-52 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 3.4E-52 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 3.4E-52 T 28-03-2018 CP478_RS09075 460baf738d33e8af72f0ef70295fe5bc 470 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 3.4E-52 T 28-03-2018 CP478_RS02355 1c56ad21b09fbac9a683833e29a698a1 171 SUPERFAMILY SSF109854 10 168 1.19E-29 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS02355 1c56ad21b09fbac9a683833e29a698a1 171 Pfam PF04978 Protein of unknown function (DUF664) 12 169 3.2E-41 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CP478_RS02355 1c56ad21b09fbac9a683833e29a698a1 171 Gene3D G3DSA:1.20.120.450 3 171 4.5E-32 T 28-03-2018 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Pfam PF00271 Helicase conserved C-terminal domain 508 628 1.8E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Gene3D G3DSA:3.40.50.300 271 485 3.4E-36 T 28-03-2018 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Gene3D G3DSA:3.40.50.300 491 670 1.0E-27 T 28-03-2018 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SUPERFAMILY SSF52540 204 481 9.58E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 706 4.5E-246 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SMART SM00490 544 629 8.9E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Gene3D G3DSA:2.40.50.140 47 145 4.0E-13 T 28-03-2018 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SMART SM00487 284 488 1.1E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SUPERFAMILY SSF50249 169 199 7.71E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SUPERFAMILY SSF50249 13 142 7.71E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Pfam PF00270 DEAD/DEAH box helicase 292 464 1.4E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 Pfam PF17191 RecG wedge domain 21 135 4.3E-6 T 28-03-2018 IPR033454 RecG, wedge domain CP478_RS16255 e56f9bcd59899f6ce77d2c6515e38e4e 737 SUPERFAMILY SSF52540 418 636 1.36E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Gene3D G3DSA:3.30.365.10 488 616 2.0E-38 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 SUPERFAMILY SSF56003 138 793 2.36E-199 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 170 729 9.0E-171 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 SMART SM01008 37 146 1.1E-48 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Gene3D G3DSA:3.30.365.10 617 797 1.4E-50 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 TIGRFAM TIGR02416 CO_dehy_Mo_lg: carbon-monoxide dehydrogenase, large subunit 31 790 0.0 T 28-03-2018 IPR012780 Carbon-monoxide dehydrogenase, large subunit GO:0005507|GO:0018492|GO:0030151 MetaCyc: PWY-7750 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 SUPERFAMILY SSF54665 26 166 4.58E-44 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Gene3D G3DSA:3.30.365.10 288 452 1.7E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 38 145 2.2E-36 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Gene3D G3DSA:3.30.365.10 178 287 1.7E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CP478_RS01990 328283992a43b08e45ea1ab91d6bf8af 799 Gene3D G3DSA:3.90.1170.50 3 146 1.3E-38 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 Gene3D G3DSA:3.40.50.150 249 457 2.5E-48 T 28-03-2018 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 SUPERFAMILY SSF53335 156 455 9.03E-55 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 Gene3D G3DSA:1.10.940.10 12 153 1.0E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 335 346 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 Pfam PF01189 16S rRNA methyltransferase RsmB/F 260 454 3.1E-66 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 Pfam PF01029 NusB family 15 137 2.6E-24 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 SUPERFAMILY SSF48013 15 170 1.7E-31 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 240 254 1.1E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 273 283 1.1E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 386 402 1.1E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 438 455 1.1E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS07705 d49ea301991905053ed5917c330b5f5b 457 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 336 348 1.1E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CP478_RS09290 717cdda7f1ec5abd6c31bb64df67a9fc 249 SUPERFAMILY SSF53335 34 217 6.69E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS09290 717cdda7f1ec5abd6c31bb64df67a9fc 249 Pfam PF01596 O-methyltransferase 56 204 4.1E-14 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CP478_RS09290 717cdda7f1ec5abd6c31bb64df67a9fc 249 Gene3D G3DSA:3.40.50.150 56 237 2.2E-25 T 28-03-2018 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 Pfam PF01266 FAD dependent oxidoreductase 37 366 8.2E-48 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 385 395 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 Gene3D G3DSA:3.50.50.60 15 95 3.8E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 59 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 65 77 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 380 392 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 48 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 111 123 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 350 356 4.5E-34 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 SUPERFAMILY SSF51905 299 360 6.09E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 SUPERFAMILY SSF51905 35 262 6.09E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 41 58 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 413 536 9.6E-28 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 Gene3D G3DSA:3.30.9.10 115 221 4.9E-20 T 28-03-2018 CP478_RS18090 724338dd47dbd7b0d69ea89dea61b3a7 585 Gene3D G3DSA:3.30.9.10 222 357 2.3E-38 T 28-03-2018 CP478_RS13210 3d69ea93e090d52adb31be13aec8915b 126 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 22.468 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CP478_RS13210 3d69ea93e090d52adb31be13aec8915b 126 SUPERFAMILY SSF81301 7 118 5.23E-38 T 28-03-2018 CP478_RS13210 3d69ea93e090d52adb31be13aec8915b 126 Pfam PF02410 Ribosomal silencing factor during starvation 16 108 4.0E-24 T 28-03-2018 CP478_RS13210 3d69ea93e090d52adb31be13aec8915b 126 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 108 1.5E-31 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CP478_RS13210 3d69ea93e090d52adb31be13aec8915b 126 Gene3D G3DSA:3.30.460.10 4 112 5.3E-31 T 28-03-2018 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SUPERFAMILY SSF52540 435 702 1.85E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 753 1309 2.1E-165 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 Gene3D G3DSA:3.40.50.300 440 692 3.5E-21 T 28-03-2018 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 Gene3D G3DSA:3.40.50.300 795 1001 1.7E-7 T 28-03-2018 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 Gene3D G3DSA:3.40.50.300 1072 1310 8.0E-6 T 28-03-2018 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SUPERFAMILY SSF52540 822 1001 3.6E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SMART SM00382 1099 1302 0.02 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SMART SM00382 471 661 0.66 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SMART SM00382 821 995 0.41 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 Pfam PF01580 FtsK/SpoIIIE family 787 1037 7.7E-73 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 Pfam PF01580 FtsK/SpoIIIE family 441 635 2.1E-19 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 SUPERFAMILY SSF52540 1078 1307 3.55E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01535 0d04d00b92b1ff5593489a7d8e9609bd 1330 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 705 3.7E-225 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 Gene3D G3DSA:1.10.10.10 2 109 2.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 SMART SM00347 25 125 1.1E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 SUPERFAMILY SSF46785 5 140 1.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 Gene3D G3DSA:1.10.287.100 110 140 1.3E-10 T 28-03-2018 CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CP478_RS04800 c13a3add5208e9a6796f61455548f05c 143 Pfam PF01047 MarR family 33 90 9.4E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS10670 3c068e39f2ca3cfcd86f73cc5c5f40ed 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 128 13.124 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS10670 3c068e39f2ca3cfcd86f73cc5c5f40ed 135 SUPERFAMILY SSF88723 2 124 1.4E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10670 3c068e39f2ca3cfcd86f73cc5c5f40ed 135 Pfam PF01850 PIN domain 2 122 1.3E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS10670 3c068e39f2ca3cfcd86f73cc5c5f40ed 135 Gene3D G3DSA:3.40.50.1010 1 134 1.4E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01365 a63f0eafd50113758b2daeb6c97650d2 118 SUPERFAMILY SSF50022 10 114 9.98E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS01365 a63f0eafd50113758b2daeb6c97650d2 118 Gene3D G3DSA:2.102.10.10 2 118 1.7E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS01365 a63f0eafd50113758b2daeb6c97650d2 118 Pfam PF13806 Rieske-like [2Fe-2S] domain 10 113 7.0E-35 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CP478_RS01365 a63f0eafd50113758b2daeb6c97650d2 118 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 10 114 1.4E-27 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CP478_RS02815 33f5c894be245760ff3568bcaea7a765 216 Gene3D G3DSA:3.40.30.10 73 206 6.8E-24 T 28-03-2018 CP478_RS02815 33f5c894be245760ff3568bcaea7a765 216 ProSitePatterns PS00194 Thioredoxin family active site. 91 109 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CP478_RS02815 33f5c894be245760ff3568bcaea7a765 216 Pfam PF00578 AhpC/TSA family 78 184 6.6E-16 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS02815 33f5c894be245760ff3568bcaea7a765 216 SUPERFAMILY SSF52833 17 199 1.76E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS05040 ea7735bee1fcb8c9cdd8eaaec4a0278d 354 SUPERFAMILY SSF110857 4 135 1.03E-24 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CP478_RS05040 ea7735bee1fcb8c9cdd8eaaec4a0278d 354 Pfam PF05908 Poly-gamma-glutamate hydrolase 168 322 2.0E-42 T 28-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CP478_RS05040 ea7735bee1fcb8c9cdd8eaaec4a0278d 354 Pfam PF13772 AIG2-like family 57 137 6.0E-14 T 28-03-2018 CP478_RS05040 ea7735bee1fcb8c9cdd8eaaec4a0278d 354 Gene3D G3DSA:3.10.490.10 1 150 9.0E-39 T 28-03-2018 CP478_RS09850 aea647d516c75fdb90a60af39e179328 468 SUPERFAMILY SSF140459 2 174 4.18E-62 T 28-03-2018 CP478_RS09850 aea647d516c75fdb90a60af39e179328 468 Gene3D G3DSA:1.10.287.1060 21 105 6.3E-5 T 28-03-2018 CP478_RS09850 aea647d516c75fdb90a60af39e179328 468 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 316 384 2.7E-12 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09850 aea647d516c75fdb90a60af39e179328 468 Pfam PF00823 PPE family 7 161 2.8E-60 T 28-03-2018 IPR000030 PPE family CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Gene3D G3DSA:1.20.140.10 275 476 2.4E-34 T 28-03-2018 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Gene3D G3DSA:2.40.110.10 160 274 6.6E-26 T 28-03-2018 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Gene3D G3DSA:1.10.540.10 31 156 1.1E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 5.3E-9 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 SUPERFAMILY SSF56645 37 278 1.31E-43 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 474 604 1.2E-29 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 SUPERFAMILY SSF47203 292 467 3.7E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 3.7E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS08040 d11c52c74bd7bbd93f4837d29bcaf8a8 609 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.3E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS02400 f576c6391e707c636a7d08ffb65cd621 236 SUPERFAMILY SSF46689 17 90 8.72E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS02400 f576c6391e707c636a7d08ffb65cd621 236 Gene3D G3DSA:1.10.357.10 19 226 3.1E-23 T 28-03-2018 CP478_RS02400 f576c6391e707c636a7d08ffb65cd621 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 3.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 Gene3D G3DSA:3.40.50.300 251 458 1.4E-40 T 28-03-2018 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 Gene3D G3DSA:3.40.50.300 476 692 1.4E-43 T 28-03-2018 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 SMART SM00382 277 434 2.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 SMART SM00382 506 683 1.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 SUPERFAMILY SSF52540 469 685 2.72E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 ProSitePatterns PS00211 ABC transporters family signature. 374 388 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 Pfam PF00005 ABC transporter 268 401 4.4E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 Pfam PF00005 ABC transporter 497 634 7.8E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 SUPERFAMILY SSF52540 245 448 1.02E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12680 1272693b038e9d4802ac0175c6950f7a 697 ProSitePatterns PS00211 ABC transporters family signature. 607 621 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS19330 1333b8fe02080611d253b4798acca265 261 SUPERFAMILY SSF56529 5 260 2.29E-73 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS19330 1333b8fe02080611d253b4798acca265 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 92 257 1.1E-11 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS19330 1333b8fe02080611d253b4798acca265 261 Gene3D G3DSA:3.90.850.10 1 261 1.5E-51 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 SUPERFAMILY SSF48295 399 503 8.11E-31 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Gene3D G3DSA:1.10.1750.10 409 504 6.9E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 502 32.297 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 SMART SM00760 412 480 2.1E-31 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 SMART SM00382 200 328 1.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 299 326 1.0E-48 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 461 480 1.0E-48 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 201 221 1.0E-48 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 233 247 1.0E-48 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 265 279 1.0E-48 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 415 480 7.8E-27 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 SUPERFAMILY SSF52540 167 379 1.43E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 ProSitePatterns PS01008 DnaA protein signature. 462 480 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Gene3D G3DSA:3.40.50.300 165 332 2.3E-21 T 28-03-2018 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Pfam PF00308 Bacterial dnaA protein 168 385 2.3E-103 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 43 501 3.1E-151 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CP478_RS00005 3f563a825492be0ef2389e44bb6fea04 507 Gene3D G3DSA:1.10.8.60 334 405 3.8E-26 T 28-03-2018 CP478_RS09295 f70a04b546c1a1539fe69c3be03f062c 556 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CP478_RS09295 f70a04b546c1a1539fe69c3be03f062c 556 PIRSF PIRSF006060 4 467 2.4E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS09295 f70a04b546c1a1539fe69c3be03f062c 556 Pfam PF00324 Amino acid permease 25 433 7.1E-97 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 Pfam PF00137 ATP synthase subunit C 11 70 8.1E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.4E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 PRINTS PR00124 ATP synthase C subunit signature 50 75 1.4E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.4E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 13.676 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 21 77 1.9E-14 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 SUPERFAMILY SSF81333 5 78 3.4E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CP478_RS07150 c0928eadf8e5ae19c66441b17ae1bcc1 81 Gene3D G3DSA:1.20.20.10 5 77 2.7E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CP478_RS13680 3b43db0a826b8f0f26a84a16247aee88 529 SUPERFAMILY SSF52096 19 257 5.58E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS13680 3b43db0a826b8f0f26a84a16247aee88 529 Pfam PF01039 Carboxyl transferase domain 42 518 2.3E-148 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS13680 3b43db0a826b8f0f26a84a16247aee88 529 SUPERFAMILY SSF52096 231 511 3.32E-85 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS13680 3b43db0a826b8f0f26a84a16247aee88 529 Gene3D G3DSA:3.90.226.10 265 522 1.0E-69 T 28-03-2018 CP478_RS13680 3b43db0a826b8f0f26a84a16247aee88 529 Gene3D G3DSA:3.90.226.10 11 264 4.8E-66 T 28-03-2018 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 403 1.5E-133 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 413 40.604 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 320 341 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 SUPERFAMILY SSF53720 13 413 1.7E-111 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 Gene3D G3DSA:3.40.605.10 3 245 7.2E-43 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 Pfam PF00171 Aldehyde dehydrogenase family 12 301 1.5E-13 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 Pfam PF00171 Aldehyde dehydrogenase family 316 404 1.5E-6 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 PIRSF PIRSF000151 7 414 4.3E-167 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CP478_RS13250 4978e5a0218b975bc2273c383ec8d9c3 415 Gene3D G3DSA:3.40.605.10 246 415 1.4E-39 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 291 6.0E-69 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 Gene3D G3DSA:1.10.287.890 198 282 1.1E-19 T 28-03-2018 CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 SUPERFAMILY SSF52540 5 150 2.44E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 3 308 25.548 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 Pfam PF01715 IPP transferase 40 286 7.2E-70 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CP478_RS14940 c9c4010d4484b350292c2dd2706aa8d8 314 Gene3D G3DSA:3.40.50.300 2 191 1.0E-56 T 28-03-2018 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 Gene3D G3DSA:1.10.10.10 23 135 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 82 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 99 114 1.9E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 SMART SM00418 50 128 2.3E-28 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 SUPERFAMILY SSF46785 38 123 3.01E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12865 17400644e548dfa2a96fc363f35033d3 135 Pfam PF01022 Bacterial regulatory protein, arsR family 58 102 6.4E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS05130 dc0cfb2ba32a0bca8d51bb1971a993da 257 Pfam PF01740 STAS domain 16 120 9.0E-11 T 28-03-2018 IPR002645 STAS domain CP478_RS05130 dc0cfb2ba32a0bca8d51bb1971a993da 257 Gene3D G3DSA:3.30.565.10 130 252 3.2E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05130 dc0cfb2ba32a0bca8d51bb1971a993da 257 Gene3D G3DSA:3.30.750.24 12 127 1.7E-10 T 28-03-2018 IPR002645 STAS domain CP478_RS05130 dc0cfb2ba32a0bca8d51bb1971a993da 257 SUPERFAMILY SSF52091 16 124 1.14E-11 T 28-03-2018 IPR002645 STAS domain CP478_RS16635 c33fdb54163494dbb38c6cb26c9d2535 287 Gene3D G3DSA:3.40.50.300 4 268 5.6E-44 T 28-03-2018 CP478_RS16635 c33fdb54163494dbb38c6cb26c9d2535 287 SUPERFAMILY SSF52540 18 252 8.04E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16635 c33fdb54163494dbb38c6cb26c9d2535 287 Pfam PF00005 ABC transporter 40 188 3.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS16635 c33fdb54163494dbb38c6cb26c9d2535 287 SMART SM00382 46 248 3.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS13500 59b40e61fdd062b109cf985f81191ca7 222 SMART SM00507 125 174 9.9E-16 T 28-03-2018 IPR003615 HNH nuclease CP478_RS13500 59b40e61fdd062b109cf985f81191ca7 222 Pfam PF14279 HNH endonuclease 138 184 2.6E-13 T 28-03-2018 IPR029471 HNH endonuclease 5 CP478_RS13500 59b40e61fdd062b109cf985f81191ca7 222 Gene3D G3DSA:3.40.1800.10 118 189 9.8E-19 T 28-03-2018 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 Gene3D G3DSA:3.40.47.10 3 247 5.9E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 SUPERFAMILY SSF53901 264 387 6.39E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 Gene3D G3DSA:3.40.47.10 257 393 1.1E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 PIRSF PIRSF000429 4 397 1.9E-70 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 Pfam PF00108 Thiolase, N-terminal domain 10 234 2.3E-21 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 Pfam PF02803 Thiolase, C-terminal domain 275 374 1.2E-9 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS15275 563d5de9ffca871f196150f4e25d3d60 401 SUPERFAMILY SSF53901 10 241 2.25E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 Gene3D G3DSA:3.40.50.980 181 349 1.1E-33 T 28-03-2018 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 Gene3D G3DSA:3.40.50.980 6 180 1.6E-21 T 28-03-2018 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 Pfam PF00501 AMP-binding enzyme 17 436 9.3E-52 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 Gene3D G3DSA:3.30.300.30 429 531 6.1E-6 T 28-03-2018 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 Gene3D G3DSA:2.30.38.10 350 428 2.8E-5 T 28-03-2018 CP478_RS00200 53cddb3952a2830d4dd6eecc82fbf7a3 562 SUPERFAMILY SSF56801 13 535 7.72E-75 T 28-03-2018 CP478_RS18070 be6eef4919951a41a9eaa2755407140e 304 Pfam PF10503 Esterase PHB depolymerase 43 174 1.4E-10 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CP478_RS18070 be6eef4919951a41a9eaa2755407140e 304 Gene3D G3DSA:3.40.50.1820 33 303 1.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18070 be6eef4919951a41a9eaa2755407140e 304 SUPERFAMILY SSF53474 245 270 1.59E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18070 be6eef4919951a41a9eaa2755407140e 304 SUPERFAMILY SSF53474 37 199 1.59E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Gene3D G3DSA:2.40.110.10 117 213 1.3E-15 T 28-03-2018 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Gene3D G3DSA:1.20.140.10 214 378 3.9E-30 T 28-03-2018 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Gene3D G3DSA:1.10.540.10 2 114 1.2E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 SUPERFAMILY SSF56645 5 220 1.96E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 370 4.9E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 211 2.0E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 SUPERFAMILY SSF47203 224 371 1.59E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS07375 b8fe043542fbb4efba7080dd045875d5 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 101 9.7E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS11485 f05a0220de5be1bf2d99f7e1070c0c9c 291 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 54 279 1.8E-107 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CP478_RS11485 f05a0220de5be1bf2d99f7e1070c0c9c 291 Pfam PF00227 Proteasome subunit 56 240 6.6E-27 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS11485 f05a0220de5be1bf2d99f7e1070c0c9c 291 Gene3D G3DSA:3.60.20.10 51 284 3.6E-34 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11485 f05a0220de5be1bf2d99f7e1070c0c9c 291 Hamap MF_02113_B Proteasome subunit beta [prcB]. 5 289 44.899 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CP478_RS11485 f05a0220de5be1bf2d99f7e1070c0c9c 291 SUPERFAMILY SSF56235 51 274 1.22E-48 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11875 19a31612a83b1b1ae726172ac91348e1 409 Pfam PF02374 Anion-transporting ATPase 3 309 4.8E-40 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CP478_RS11875 19a31612a83b1b1ae726172ac91348e1 409 SUPERFAMILY SSF52540 3 298 1.7E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11875 19a31612a83b1b1ae726172ac91348e1 409 Gene3D G3DSA:3.40.50.300 1 323 1.1E-46 T 28-03-2018 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 SUPERFAMILY SSF47323 355 514 1.81E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 SUPERFAMILY SSF52374 2 353 1.26E-105 T 28-03-2018 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 Gene3D G3DSA:1.10.730.10 347 512 8.1E-40 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 Pfam PF09334 tRNA synthetases class I (M) 4 137 5.6E-43 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 Pfam PF09334 tRNA synthetases class I (M) 149 362 3.6E-64 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 Gene3D G3DSA:3.40.50.620 1 346 1.6E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 511 46.901 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 483 6.8E-145 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 225 236 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS05510 959312011544cedbfbddf07d3918f0f3 519 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 4.9E-34 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 SMART SM00382 30 213 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 Gene3D G3DSA:3.40.50.300 1 238 6.8E-68 T 28-03-2018 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 SUPERFAMILY SSF52540 5 245 4.32E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 SUPERFAMILY SSF50331 238 355 2.3E-23 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 Gene3D G3DSA:2.40.50.140 290 339 5.3E-15 T 28-03-2018 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 Pfam PF08402 TOBE domain 275 348 1.6E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 Pfam PF00005 ABC transporter 21 163 1.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS11120 21e65093371a69f6e881d90b2f8045d8 357 Gene3D G3DSA:2.40.50.100 241 289 7.4E-7 T 28-03-2018 CP478_RS17940 43e62147482bcae074ed9fdae92bbd45 394 Gene3D G3DSA:3.40.50.10540 4 393 4.0E-109 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS17940 43e62147482bcae074ed9fdae92bbd45 394 SUPERFAMILY SSF89796 8 389 1.96E-107 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS17940 43e62147482bcae074ed9fdae92bbd45 394 Pfam PF02515 CoA-transferase family III 10 387 3.3E-122 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CP478_RS03930 2db787a0e306fbfa31c1eb01875fa377 367 SUPERFAMILY SSF53335 20 311 7.84E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03930 2db787a0e306fbfa31c1eb01875fa377 367 Gene3D G3DSA:3.40.50.150 8 300 1.0E-55 T 28-03-2018 CP478_RS03930 2db787a0e306fbfa31c1eb01875fa377 367 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 22 287 9.0E-83 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS03930 2db787a0e306fbfa31c1eb01875fa377 367 Pfam PF04072 Leucine carboxyl methyltransferase 24 209 2.8E-67 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS10365 66df289581ef423839110a0279be6c88 143 Gene3D G3DSA:3.30.750.24 28 135 4.3E-12 T 28-03-2018 IPR002645 STAS domain CP478_RS10365 66df289581ef423839110a0279be6c88 143 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 28 134 6.2E-33 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CP478_RS10365 66df289581ef423839110a0279be6c88 143 SUPERFAMILY SSF52091 32 137 6.67E-16 T 28-03-2018 IPR002645 STAS domain CP478_RS10365 66df289581ef423839110a0279be6c88 143 Pfam PF01740 STAS domain 32 135 1.8E-14 T 28-03-2018 IPR002645 STAS domain CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 99 1.2E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 Gene3D G3DSA:1.10.540.10 25 101 4.1E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 Gene3D G3DSA:1.20.140.10 189 337 2.8E-21 T 28-03-2018 CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 SUPERFAMILY SSF56645 1 190 6.28E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 327 8.1E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19370 8d66813f4b73c3dd848094c0831ad16c 339 SUPERFAMILY SSF47203 200 333 1.77E-23 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS00775 26818c66236e438d989631ee83029d92 492 PRINTS PR00762 Chloride channel signature 412 428 2.6E-14 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 PRINTS PR00762 Chloride channel signature 206 225 2.6E-14 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 PRINTS PR00762 Chloride channel signature 126 143 2.6E-14 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 PRINTS PR00762 Chloride channel signature 376 396 2.6E-14 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 PRINTS PR00762 Chloride channel signature 430 449 2.6E-14 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 Gene3D G3DSA:1.10.3080.10 36 484 7.8E-78 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 Pfam PF00654 Voltage gated chloride channel 113 460 4.1E-80 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CP478_RS00775 26818c66236e438d989631ee83029d92 492 SUPERFAMILY SSF81340 40 476 4.97E-89 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CP478_RS10910 fe882dfdd905cc05e6247f0f6fe91acb 250 SUPERFAMILY SSF54637 18 149 5.22E-14 T 28-03-2018 IPR029069 HotDog domain CP478_RS10910 fe882dfdd905cc05e6247f0f6fe91acb 250 Gene3D G3DSA:3.10.129.10 13 154 1.2E-9 T 28-03-2018 CP478_RS10910 fe882dfdd905cc05e6247f0f6fe91acb 250 SUPERFAMILY SSF54637 164 242 3.02E-10 T 28-03-2018 IPR029069 HotDog domain CP478_RS10910 fe882dfdd905cc05e6247f0f6fe91acb 250 Pfam PF01643 Acyl-ACP thioesterase 18 228 3.7E-36 T 28-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CP478_RS10910 fe882dfdd905cc05e6247f0f6fe91acb 250 Gene3D G3DSA:3.10.129.10 160 247 7.0E-7 T 28-03-2018 CP478_RS17300 47351510103424e59337fdeef71184e0 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17300 47351510103424e59337fdeef71184e0 213 Gene3D G3DSA:1.10.357.10 62 192 6.3E-11 T 28-03-2018 CP478_RS17300 47351510103424e59337fdeef71184e0 213 Gene3D G3DSA:1.10.10.60 6 61 4.9E-16 T 28-03-2018 CP478_RS17300 47351510103424e59337fdeef71184e0 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS17300 47351510103424e59337fdeef71184e0 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17300 47351510103424e59337fdeef71184e0 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17300 47351510103424e59337fdeef71184e0 213 SUPERFAMILY SSF48498 85 186 4.45E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS17300 47351510103424e59337fdeef71184e0 213 SUPERFAMILY SSF46689 7 77 1.6E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS07920 7b6f6da640b42a3e1e998dbbdb604834 136 Gene3D G3DSA:1.20.5.110 70 107 0.0083 T 28-03-2018 CP478_RS07920 7b6f6da640b42a3e1e998dbbdb604834 136 Pfam PF03670 Uncharacterised protein family (UPF0184) 44 77 2.1E-4 T 28-03-2018 IPR022788 Uncharacterised protein family UPF0184 CP478_RS07920 7b6f6da640b42a3e1e998dbbdb604834 136 Gene3D G3DSA:1.20.5.1070 5 69 4.1E-6 T 28-03-2018 CP478_RS13275 193709830cd48a945552cc3f18a731da 194 Pfam PF00823 PPE family 5 159 2.6E-50 T 28-03-2018 IPR000030 PPE family CP478_RS13275 193709830cd48a945552cc3f18a731da 194 SUPERFAMILY SSF140459 3 173 2.62E-51 T 28-03-2018 CP478_RS13275 193709830cd48a945552cc3f18a731da 194 Gene3D G3DSA:1.10.287.1060 20 109 1.0E-7 T 28-03-2018 CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 Gene3D G3DSA:3.40.50.620 3 148 2.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 PRINTS PR01438 Universal stress protein signature 271 293 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 PRINTS PR01438 Universal stress protein signature 253 265 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 PRINTS PR01438 Universal stress protein signature 159 177 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 Pfam PF00582 Universal stress protein family 162 293 9.1E-25 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 Pfam PF00582 Universal stress protein family 10 148 1.1E-21 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 SUPERFAMILY SSF52402 161 294 1.93E-28 T 28-03-2018 CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 Gene3D G3DSA:3.40.50.620 149 297 5.8E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS14370 bdc047082aa5a64ef923493514afe89f 297 SUPERFAMILY SSF52402 10 153 1.84E-25 T 28-03-2018 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 PIRSF PIRSF005578 1 263 3.6E-95 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 SUPERFAMILY SSF53335 62 244 2.24E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 Gene3D G3DSA:3.40.50.150 65 266 6.4E-54 T 28-03-2018 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 Pfam PF01479 S4 domain 6 46 4.1E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 7.0E-62 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 SUPERFAMILY SSF55174 4 63 1.43E-9 T 28-03-2018 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 SMART SM00363 5 68 2.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 Pfam PF01728 FtsJ-like methyltransferase 62 243 2.2E-22 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CP478_RS09245 95dad51d7685d3ec0223e214e1fcd69b 268 Gene3D G3DSA:3.10.290.10 2 64 2.0E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS18520 8eaea7e6c14f072ad8de09075122d2b5 329 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 20 301 7.6E-91 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS18520 8eaea7e6c14f072ad8de09075122d2b5 329 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 18 304 36.586 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS18520 8eaea7e6c14f072ad8de09075122d2b5 329 Gene3D G3DSA:3.40.50.2300 212 314 0.012 T 28-03-2018 CP478_RS18520 8eaea7e6c14f072ad8de09075122d2b5 329 Gene3D G3DSA:3.40.50.2300 106 211 0.056 T 28-03-2018 CP478_RS18520 8eaea7e6c14f072ad8de09075122d2b5 329 Pfam PF02401 LytB protein 20 300 3.0E-85 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS04310 d06f46e7281c41eee470814e3f7e23f5 101 SUPERFAMILY SSF54909 4 97 1.44E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS04310 d06f46e7281c41eee470814e3f7e23f5 101 Gene3D G3DSA:3.30.70.100 1 101 2.2E-23 T 28-03-2018 CP478_RS04310 d06f46e7281c41eee470814e3f7e23f5 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 78 4.3E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 232 264 1.1E-15 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 Gene3D G3DSA:3.30.60.70 111 150 2.8E-20 T 28-03-2018 CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 317 7.6E-160 T 28-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 111 150 2.3E-20 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 315 44.814 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 Gene3D G3DSA:2.160.10.10 151 280 6.2E-17 T 28-03-2018 CP478_RS06585 a832098e25eb8031d1065fd4f402b412 317 SUPERFAMILY SSF51161 71 297 1.04E-38 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 SUPERFAMILY SSF52540 329 568 2.15E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 Pfam PF00005 ABC transporter 349 498 1.6E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 Gene3D G3DSA:3.40.50.300 324 574 3.0E-70 T 28-03-2018 CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 SMART SM00382 358 544 2.1E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 Gene3D G3DSA:1.20.1560.10 2 313 1.4E-17 T 28-03-2018 CP478_RS07395 d3bced7cce4481669a2ac92d0e52fe5e 579 SUPERFAMILY SSF90123 11 307 4.58E-27 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Pfam PF04898 Glutamate synthase central domain 466 757 8.3E-113 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 SUPERFAMILY SSF51395 455 1225 1.34E-262 T 28-03-2018 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Pfam PF00310 Glutamine amidotransferases class-II 18 439 3.6E-180 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Gene3D G3DSA:3.60.20.10 18 449 2.1E-165 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Gene3D G3DSA:2.160.20.60 1246 1521 5.7E-114 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Pfam PF01493 GXGXG motif 1271 1458 3.8E-81 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Pfam PF01645 Conserved region in glutamate synthase 821 1190 1.4E-152 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Gene3D G3DSA:3.20.20.70 450 802 4.0E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 Gene3D G3DSA:3.20.20.70 803 1243 7.4E-158 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 SUPERFAMILY SSF56235 18 441 1.54E-146 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS21095 de8cb81294a538ba63f67bfe90bafc55 1527 SUPERFAMILY SSF69336 1240 1507 5.89E-93 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CP478_RS14650 572af4e3bd792b19fdec7d378d6aaf0a 528 SUPERFAMILY SSF53474 445 500 2.51E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14650 572af4e3bd792b19fdec7d378d6aaf0a 528 SUPERFAMILY SSF53474 127 186 2.51E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14650 572af4e3bd792b19fdec7d378d6aaf0a 528 SUPERFAMILY SSF53474 226 281 2.51E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14650 572af4e3bd792b19fdec7d378d6aaf0a 528 Gene3D G3DSA:3.40.50.1820 109 515 9.0E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14650 572af4e3bd792b19fdec7d378d6aaf0a 528 Pfam PF08386 TAP-like protein 425 526 1.4E-20 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 PRINTS PR00502 NUDIX hydrolase family signature 79 94 6.4E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 PRINTS PR00502 NUDIX hydrolase family signature 65 79 6.4E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 Pfam PF00293 NUDIX domain 43 153 8.6E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 SUPERFAMILY SSF55811 15 165 1.76E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS02200 b12895a04a679cf0d9fd929bdfd7dff4 217 Gene3D G3DSA:3.90.79.10 27 201 1.5E-23 T 28-03-2018 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 368 2.0E-27 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 SUPERFAMILY SSF55957 361 446 1.57E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Gene3D G3DSA:3.40.120.10 159 270 5.3E-30 T 28-03-2018 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 2.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 2.4E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 SUPERFAMILY SSF53738 3 183 2.98E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 4.1E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 256 1.5E-17 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Gene3D G3DSA:3.30.310.50 377 447 1.2E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 444 7.9E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 SUPERFAMILY SSF53738 161 258 4.71E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 4.1E-192 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 447 43.49 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Gene3D G3DSA:3.40.120.10 2 137 2.3E-43 T 28-03-2018 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 Gene3D G3DSA:3.40.120.10 271 376 8.9E-27 T 28-03-2018 CP478_RS18835 79bfc48e96300bcd1131d057d7a3ada0 448 SUPERFAMILY SSF53738 260 368 3.14E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Gene3D G3DSA:3.40.50.300 25 152 2.3E-23 T 28-03-2018 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SUPERFAMILY SSF55874 690 853 5.24E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 749 853 3.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 817 835 7.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 784 798 7.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 854 7.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 PRINTS PR00344 Bacterial sensor protein C-terminal signature 802 812 7.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SMART SM00388 632 700 9.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SUPERFAMILY SSF52402 255 368 1.03E-14 T 28-03-2018 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Gene3D G3DSA:1.10.287.130 622 683 2.1E-13 T 28-03-2018 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Pfam PF00582 Universal stress protein family 255 363 1.3E-10 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Pfam PF13493 Domain of unknown function (DUF4118) 400 507 1.5E-23 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 25 234 1.4E-98 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SUPERFAMILY SSF47384 623 700 2.16E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Gene3D G3DSA:3.40.50.620 231 378 2.8E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SUPERFAMILY SSF52540 31 150 6.34E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 SMART SM00387 748 857 3.6E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Gene3D G3DSA:3.30.565.10 684 859 8.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Pfam PF00512 His Kinase A (phospho-acceptor) domain 633 700 3.6E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05630 834d03a2936721d0cbefc55d4179c64a 860 Gene3D G3DSA:1.20.120.620 399 499 8.5E-20 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SUPERFAMILY SSF81271 439 511 8.83E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SUPERFAMILY SSF81301 238 456 1.8E-60 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SUPERFAMILY SSF55021 708 788 8.33E-15 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SMART SM00954 293 403 2.1E-60 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Pfam PF02824 TGS domain 452 511 4.6E-23 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SUPERFAMILY SSF109604 62 249 7.85E-70 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Gene3D G3DSA:3.30.70.260 713 790 1.1E-13 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Gene3D G3DSA:3.30.460.10 250 383 3.0E-42 T 28-03-2018 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Pfam PF13328 HD domain 86 233 1.5E-46 T 28-03-2018 IPR003607 HD/PDEase domain CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Pfam PF04607 Region found in RelA / SpoT proteins 293 402 4.2E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Gene3D G3DSA:3.10.20.30 446 518 1.5E-26 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 SMART SM00471 101 211 1.3E-13 T 28-03-2018 IPR003607 HD/PDEase domain CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 Pfam PF13291 ACT domain 709 785 1.2E-16 T 28-03-2018 IPR002912 ACT domain CP478_RS14155 93b056a2316aaefdc1964a8a382baf56 790 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 86 785 2.3E-282 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 SUPERFAMILY SSF82866 153 365 9.68E-6 T 28-03-2018 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 Gene3D G3DSA:1.10.287.950 483 577 3.1E-4 T 28-03-2018 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 Gene3D G3DSA:1.10.287.950 586 685 0.086 T 28-03-2018 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 Pfam PF03176 MMPL family 75 379 1.3E-63 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 Pfam PF03176 MMPL family 609 908 1.0E-10 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS16070 916c1d85c6fd87677ad8dfb7e13c6736 920 Gene3D G3DSA:1.20.1640.10 166 371 1.1E-6 T 28-03-2018 CP478_RS11115 5969baeb03538b49e3a775747ff34b35 324 Gene3D G3DSA:3.40.1090.10 5 260 2.0E-41 T 28-03-2018 CP478_RS11115 5969baeb03538b49e3a775747ff34b35 324 SUPERFAMILY SSF52151 8 310 1.05E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS11115 5969baeb03538b49e3a775747ff34b35 324 Pfam PF01734 Patatin-like phospholipase 11 209 8.5E-30 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 SUPERFAMILY SSF88659 178 234 8.41E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 SUPERFAMILY SSF88946 56 131 3.73E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 83 114 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Pfam PF04542 Sigma-70 region 2 63 129 2.3E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Gene3D G3DSA:1.10.1740.10 45 131 3.3E-23 T 28-03-2018 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Gene3D G3DSA:1.10.10.10 172 227 1.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Gene3D G3DSA:3.10.450.50 228 368 2.2E-20 T 28-03-2018 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 55 366 1.3E-140 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 SUPERFAMILY SSF54427 235 365 8.79E-20 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 234 1.3E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Pfam PF08281 Sigma-70, region 4 180 232 1.9E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS00995 df901767201f9333e8d5a53de928f1d8 370 Pfam PF12680 SnoaL-like domain 256 330 1.2E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 SUPERFAMILY SSF48179 507 647 5.87E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 328 505 2.1E-62 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 508 607 2.4E-20 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Gene3D G3DSA:3.40.50.720 277 506 1.7E-65 T 28-03-2018 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Gene3D G3DSA:1.10.1040.10 507 612 1.3E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Gene3D G3DSA:3.90.226.10 3 276 4.1E-51 T 28-03-2018 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 213 5.8E-32 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 Gene3D G3DSA:1.10.1040.10 634 720 3.9E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 SUPERFAMILY SSF48179 634 718 2.89E-12 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 SUPERFAMILY SSF51735 323 506 5.06E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04695 61e909852eb353767bbc22a823e5ea2a 720 SUPERFAMILY SSF52096 2 308 9.59E-59 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 Gene3D G3DSA:3.50.50.60 177 195 1.4E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 PIRSF PIRSF000183 1 371 1.9E-182 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 371 1.2E-208 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 Gene3D G3DSA:3.40.50.720 196 371 1.8E-42 T 28-03-2018 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 Gene3D G3DSA:3.40.50.720 1 176 8.3E-48 T 28-03-2018 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 SMART SM01002 149 297 1.2E-82 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 SUPERFAMILY SSF52283 305 360 2.47E-64 T 28-03-2018 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 SUPERFAMILY SSF52283 1 137 2.47E-64 T 28-03-2018 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 351 1.7E-80 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 28-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 SUPERFAMILY SSF51735 137 302 8.62E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 SMART SM01003 4 137 1.8E-78 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CP478_RS15225 a8a15dbd759e1d736363676a4befee71 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.2E-45 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CP478_RS02600 32655f0d1d95573530f2df0a8fc4894e 201 TIGRFAM TIGR00948 2a75: L-lysine exporter 4 178 4.5E-70 T 28-03-2018 IPR004777 L-lysine exporter/arginine exporter GO:0016021 CP478_RS02600 32655f0d1d95573530f2df0a8fc4894e 201 Pfam PF01810 LysE type translocator 3 187 8.6E-51 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CP478_RS10905 a90153edb0b3e4b160bd3837d1fb40c5 537 SUPERFAMILY SSF51971 154 287 1.53E-14 T 28-03-2018 CP478_RS10905 a90153edb0b3e4b160bd3837d1fb40c5 537 SUPERFAMILY SSF51971 48 118 1.53E-14 T 28-03-2018 CP478_RS10905 a90153edb0b3e4b160bd3837d1fb40c5 537 Pfam PF13450 NAD(P)-binding Rossmann-like domain 79 117 2.0E-5 T 28-03-2018 CP478_RS10905 a90153edb0b3e4b160bd3837d1fb40c5 537 Gene3D G3DSA:3.50.50.60 71 217 6.1E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10905 a90153edb0b3e4b160bd3837d1fb40c5 537 Gene3D G3DSA:3.50.50.60 232 394 7.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 SMART SM00116 363 411 0.0044 T 28-03-2018 IPR000644 CBS domain CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 SUPERFAMILY SSF50346 10 89 3.37E-9 T 28-03-2018 IPR011033 PRC-barrel-like CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Gene3D G3DSA:3.10.580.10 278 426 2.8E-18 T 28-03-2018 CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Pfam PF03448 MgtE intracellular N domain 186 285 2.8E-23 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 SUPERFAMILY SSF54631 286 412 4.04E-24 T 28-03-2018 CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 SMART SM00924 184 287 8.6E-32 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Gene3D G3DSA:1.25.60.10 167 277 1.1E-22 T 28-03-2018 CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Pfam PF00571 CBS domain 356 411 1.6E-6 T 28-03-2018 IPR000644 CBS domain CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Pfam PF00571 CBS domain 288 349 0.0013 T 28-03-2018 IPR000644 CBS domain CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 SUPERFAMILY SSF158791 170 282 1.57E-27 T 28-03-2018 CP478_RS06750 fec6654de916fdb8a586e2977ab6417f 435 Gene3D G3DSA:2.30.30.240 7 78 2.3E-7 T 28-03-2018 CP478_RS13155 2293736dee7d5bfa7853446bd7df63c2 279 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 82 2.4E-18 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CP478_RS13155 2293736dee7d5bfa7853446bd7df63c2 279 SUPERFAMILY SSF54001 8 268 3.08E-37 T 28-03-2018 CP478_RS13155 2293736dee7d5bfa7853446bd7df63c2 279 SMART SM00460 167 234 3.3E-21 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS13155 2293736dee7d5bfa7853446bd7df63c2 279 Pfam PF01841 Transglutaminase-like superfamily 126 232 4.2E-25 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS13155 2293736dee7d5bfa7853446bd7df63c2 279 Gene3D G3DSA:3.90.260.10 148 271 3.8E-9 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 34 627 1.1E-216 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 Gene3D G3DSA:2.60.120.260 405 626 1.0E-48 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 387 601 4.7E-40 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 SUPERFAMILY SSF49785 401 627 7.01E-47 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 38 351 5.5E-76 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 SMART SM00939 374 622 1.5E-70 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 SUPERFAMILY SSF53474 24 208 2.15E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 SUPERFAMILY SSF53474 242 410 2.15E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09980 12c525b857402edc9bdadbf1aae2872f 628 Gene3D G3DSA:3.40.50.1820 13 404 1.9E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 Gene3D G3DSA:1.10.1740.10 3 74 1.7E-12 T 28-03-2018 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 Pfam PF08281 Sigma-70, region 4 110 162 2.8E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 SUPERFAMILY SSF54427 175 283 9.61E-8 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 164 6.4E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 SUPERFAMILY SSF88946 9 87 4.71E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 Gene3D G3DSA:1.10.10.10 75 155 7.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 SUPERFAMILY SSF88659 95 165 1.2E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 Gene3D G3DSA:3.10.450.50 156 284 1.9E-11 T 28-03-2018 CP478_RS06515 b221ee7ce8b61f008dd46d2c19d1c1ff 290 Pfam PF04542 Sigma-70 region 2 12 74 1.6E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02870 4ad97d54bf8c06d4f46853aa0b1f9ceb 264 Gene3D G3DSA:3.40.50.1580 2 258 5.2E-40 T 28-03-2018 CP478_RS02870 4ad97d54bf8c06d4f46853aa0b1f9ceb 264 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 6 259 37.517 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CP478_RS02870 4ad97d54bf8c06d4f46853aa0b1f9ceb 264 Pfam PF01048 Phosphorylase superfamily 9 239 9.9E-37 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS02870 4ad97d54bf8c06d4f46853aa0b1f9ceb 264 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 7 240 2.3E-93 T 28-03-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112 CP478_RS02870 4ad97d54bf8c06d4f46853aa0b1f9ceb 264 SUPERFAMILY SSF53167 7 256 1.78E-72 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 3.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 3.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 SUPERFAMILY SSF46689 10 92 2.89E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 Gene3D G3DSA:1.10.10.60 3 51 6.5E-17 T 28-03-2018 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 Gene3D G3DSA:1.10.260.40 52 87 4.6E-8 T 28-03-2018 CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 SUPERFAMILY SSF48498 89 192 1.11E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS17365 8513838b751e0522c6753ce5741568f1 200 Gene3D G3DSA:1.10.357.10 88 198 2.4E-13 T 28-03-2018 CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 PIRSF PIRSF006728 4 428 4.8E-132 T 28-03-2018 IPR008135 Competence-induced protein CinA CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 SUPERFAMILY SSF53218 6 220 3.4E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 283 423 2.5E-44 T 28-03-2018 IPR008136 CinA, C-terminal CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 430 141.083 T 28-03-2018 IPR008135 Competence-induced protein CinA CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 SMART SM00852 8 185 3.0E-40 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 Gene3D G3DSA:3.90.950.20 261 426 4.9E-55 T 28-03-2018 CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 Pfam PF02464 Competence-damaged protein 273 423 5.2E-54 T 28-03-2018 IPR008136 CinA, C-terminal CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 6 423 2.7E-75 T 28-03-2018 IPR008135 Competence-induced protein CinA CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 Gene3D G3DSA:3.40.980.10 3 185 9.4E-46 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 SUPERFAMILY SSF142433 266 423 2.88E-51 T 28-03-2018 IPR008136 CinA, C-terminal CP478_RS10350 ae48a8fe8337e0e5e95d968b8ed8387f 430 Pfam PF00994 Probable molybdopterin binding domain 8 178 2.8E-36 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS18155 7403bef84a848cf2a4ee737ccbf0039a 365 SUPERFAMILY SSF51556 7 351 6.81E-72 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS18155 7403bef84a848cf2a4ee737ccbf0039a 365 Pfam PF00962 Adenosine/AMP deaminase 13 351 2.1E-110 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CP478_RS18155 7403bef84a848cf2a4ee737ccbf0039a 365 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 3.5E-70 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CP478_RS18155 7403bef84a848cf2a4ee737ccbf0039a 365 Gene3D G3DSA:3.20.20.140 2 353 3.1E-78 T 28-03-2018 CP478_RS18155 7403bef84a848cf2a4ee737ccbf0039a 365 Hamap MF_00540 Adenosine deaminase [add]. 8 353 54.49 T 28-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 SUPERFAMILY SSF52540 424 626 4.28E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 SMART SM00382 452 625 1.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 Gene3D G3DSA:3.40.50.300 410 627 4.5E-34 T 28-03-2018 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 Gene3D G3DSA:1.20.1560.10 23 409 3.7E-28 T 28-03-2018 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 Pfam PF06472 ABC transporter transmembrane region 2 44 358 3.6E-104 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 Pfam PF00005 ABC transporter 444 579 6.3E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 SUPERFAMILY SSF90123 555 564 1.96E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 SUPERFAMILY SSF90123 205 391 1.96E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 SUPERFAMILY SSF90123 65 163 1.96E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS09905 e475392a12c7aec338f32b8c5bef90fb 639 ProSitePatterns PS00211 ABC transporters family signature. 551 565 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 Pfam PF00106 short chain dehydrogenase 8 182 1.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 SUPERFAMILY SSF51735 1 205 1.48E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 5.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 5.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17370 a47649fd735bca066a4097ad4444aa0f 235 Gene3D G3DSA:3.40.50.720 1 234 1.4E-44 T 28-03-2018 CP478_RS11610 5735f83ce1306393a2d857ad380bdd11 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 198 2.3E-44 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS11610 5735f83ce1306393a2d857ad380bdd11 236 SMART SM00855 2 159 4.5E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS11610 5735f83ce1306393a2d857ad380bdd11 236 SUPERFAMILY SSF53254 1 200 7.92E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS11610 5735f83ce1306393a2d857ad380bdd11 236 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 2 203 9.6E-100 T 28-03-2018 IPR022492 Phosphomutase MSMEG4193, putative CP478_RS11610 5735f83ce1306393a2d857ad380bdd11 236 Gene3D G3DSA:3.40.50.1240 1 211 7.5E-38 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 Gene3D G3DSA:1.20.1250.20 266 509 1.1E-14 T 28-03-2018 CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 SUPERFAMILY SSF103473 252 433 1.06E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 SUPERFAMILY SSF103473 468 507 1.06E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 SUPERFAMILY SSF103473 3 198 1.06E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 Gene3D G3DSA:1.20.1250.20 1 202 7.2E-31 T 28-03-2018 CP478_RS07720 ea0e17b06956a4ac3db4c9656899acc1 518 Pfam PF07690 Major Facilitator Superfamily 14 424 7.6E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 SUPERFAMILY SSF56645 3 242 2.49E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Gene3D G3DSA:1.20.140.10 229 385 8.2E-37 T 28-03-2018 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 117 8.3E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Gene3D G3DSA:2.40.110.10 124 228 1.6E-31 T 28-03-2018 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 SUPERFAMILY SSF47203 231 379 1.37E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Gene3D G3DSA:1.10.540.10 2 122 9.2E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 2.3E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS19455 1ddaa083ed91d6edb74afb3227be2a5f 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 377 2.2E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS20725 f4284ca8e4d0c973ea189aa132362e58 1094 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 11 667 3.6E-264 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CP478_RS20725 f4284ca8e4d0c973ea189aa132362e58 1094 Pfam PF14896 EmbC C-terminal domain 702 1091 5.9E-149 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CP478_RS20725 f4284ca8e4d0c973ea189aa132362e58 1094 Gene3D G3DSA:2.60.120.610 33 205 4.6E-54 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CP478_RS17540 924366256765c04ff92265bc3459c54f 355 SUPERFAMILY SSF81324 27 167 3.27E-21 T 28-03-2018 CP478_RS17540 924366256765c04ff92265bc3459c54f 355 Pfam PF02254 TrkA-N domain 150 266 6.7E-27 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CP478_RS17540 924366256765c04ff92265bc3459c54f 355 Gene3D G3DSA:3.40.50.720 139 266 4.9E-24 T 28-03-2018 CP478_RS17540 924366256765c04ff92265bc3459c54f 355 SUPERFAMILY SSF51735 145 289 9.19E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17540 924366256765c04ff92265bc3459c54f 355 Pfam PF07885 Ion channel 49 129 1.2E-13 T 28-03-2018 IPR013099 Potassium channel domain CP478_RS17540 924366256765c04ff92265bc3459c54f 355 Gene3D G3DSA:1.10.287.70 37 138 2.0E-15 T 28-03-2018 CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 ProSitePatterns PS00523 Sulfatases signature 1. 87 99 - T 28-03-2018 IPR024607 Sulfatase, conserved site CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 Gene3D G3DSA:2.60.120.200 605 762 1.4E-12 T 28-03-2018 CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 SUPERFAMILY SSF49899 588 761 1.95E-7 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 Gene3D G3DSA:3.30.1120.10 489 584 2.0E-16 T 28-03-2018 CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 Gene3D G3DSA:3.40.720.10 40 488 3.0E-85 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 SUPERFAMILY SSF53649 43 573 2.62E-122 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS03575 133415e3a6362bc9b6a540d38011ac47 787 Pfam PF00884 Sulfatase 43 459 8.1E-94 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CP478_RS18050 9de8d81b98125bea69b8d5529573e8f5 269 Pfam PF13635 Domain of unknown function (DUF4143) 54 214 5.7E-26 T 28-03-2018 IPR025420 Domain of unknown function DUF4143 CP478_RS20665 d6081a3bb79bd8cebe47752bb656d459 304 SUPERFAMILY SSF53448 3 277 1.04E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20665 d6081a3bb79bd8cebe47752bb656d459 304 Gene3D G3DSA:3.90.550.10 2 272 1.2E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS20665 d6081a3bb79bd8cebe47752bb656d459 304 Pfam PF13641 Glycosyltransferase like family 2 6 213 1.9E-9 T 28-03-2018 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 SUPERFAMILY SSF47203 230 374 1.21E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Gene3D G3DSA:1.20.140.10 223 377 2.7E-37 T 28-03-2018 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 370 1.1E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Gene3D G3DSA:1.10.540.10 1 119 2.6E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Gene3D G3DSA:2.40.110.10 120 222 4.6E-28 T 28-03-2018 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 7.7E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 1.0E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS19465 e945e1e0d52ca8d7720955f700d16f0e 377 SUPERFAMILY SSF56645 2 239 9.03E-62 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS06595 66c7bc840da206a2a836ed1177f80dfb 194 Gene3D G3DSA:1.25.40.10 1 114 3.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 Pfam PF00902 Sec-independent protein translocase protein (TatC) 29 252 1.6E-59 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 27 260 2.3E-78 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 21 274 17.816 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 ProSitePatterns PS01218 TatC family signature. 187 206 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 26 53 8.7E-41 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 137 163 8.7E-41 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 187 215 8.7E-41 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS11400 517d5bd200042cc31bcbee04b6f8d362 308 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 119 137 8.7E-41 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CP478_RS09315 dbde003aa2ea43f092c73a83f4d77a02 486 Pfam PF00916 Sulfate permease family 141 353 5.1E-40 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CP478_RS09315 dbde003aa2ea43f092c73a83f4d77a02 486 Pfam PF00916 Sulfate permease family 7 133 5.9E-26 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CP478_RS09315 dbde003aa2ea43f092c73a83f4d77a02 486 Pfam PF01740 STAS domain 390 479 9.6E-9 T 28-03-2018 IPR002645 STAS domain CP478_RS09315 dbde003aa2ea43f092c73a83f4d77a02 486 Gene3D G3DSA:3.30.750.24 377 477 8.4E-10 T 28-03-2018 IPR002645 STAS domain CP478_RS09315 dbde003aa2ea43f092c73a83f4d77a02 486 SUPERFAMILY SSF52091 390 468 9.03E-11 T 28-03-2018 IPR002645 STAS domain CP478_RS13230 5a43f522fb759cf5eb9544698e1f40a1 348 Gene3D G3DSA:3.40.50.150 58 329 9.9E-21 T 28-03-2018 CP478_RS13230 5a43f522fb759cf5eb9544698e1f40a1 348 Pfam PF13649 Methyltransferase domain 150 245 1.4E-9 T 28-03-2018 CP478_RS13230 5a43f522fb759cf5eb9544698e1f40a1 348 SUPERFAMILY SSF53335 104 304 3.19E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 SUPERFAMILY SSF53067 159 348 7.92E-29 T 28-03-2018 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 Pfam PF00012 Hsp70 protein 154 347 1.0E-17 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 Gene3D G3DSA:3.30.420.40 4 387 4.4E-35 T 28-03-2018 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 PRINTS PR01217 Proline rich extensin signature 466 487 7.9E-12 T 28-03-2018 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 PRINTS PR01217 Proline rich extensin signature 513 530 7.9E-12 T 28-03-2018 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 PRINTS PR01217 Proline rich extensin signature 495 511 7.9E-12 T 28-03-2018 CP478_RS01670 b77cbf4e3b6550c6490480d5a5921757 620 PRINTS PR01217 Proline rich extensin signature 535 560 7.9E-12 T 28-03-2018 CP478_RS17175 5f6c188d109ae5b84c939343d9a599b4 380 Pfam PF00823 PPE family 6 162 1.3E-60 T 28-03-2018 IPR000030 PPE family CP478_RS17175 5f6c188d109ae5b84c939343d9a599b4 380 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 300 376 3.1E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS17175 5f6c188d109ae5b84c939343d9a599b4 380 Gene3D G3DSA:1.10.287.1060 20 103 9.0E-6 T 28-03-2018 CP478_RS17175 5f6c188d109ae5b84c939343d9a599b4 380 SUPERFAMILY SSF140459 2 174 5.75E-63 T 28-03-2018 CP478_RS03585 3999ce6b98d7cfa1d40093eb1b24c295 112 SUPERFAMILY SSF88723 10 109 4.25E-10 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03585 3999ce6b98d7cfa1d40093eb1b24c295 112 Pfam PF01850 PIN domain 10 109 2.7E-5 T 28-03-2018 IPR002716 PIN domain CP478_RS03585 3999ce6b98d7cfa1d40093eb1b24c295 112 Gene3D G3DSA:3.40.50.1010 9 111 2.4E-8 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 Gene3D G3DSA:2.40.50.140 293 372 6.8E-16 T 28-03-2018 CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 Gene3D G3DSA:2.40.50.100 240 292 7.1E-11 T 28-03-2018 CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 Pfam PF00005 ABC transporter 21 162 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 SUPERFAMILY SSF52540 4 243 7.37E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 SUPERFAMILY SSF50331 237 388 3.12E-22 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 SMART SM00382 29 220 3.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS06780 a3d2dc68b7aff7b140d041a2c9fbddc4 393 Gene3D G3DSA:3.40.50.300 1 237 3.7E-73 T 28-03-2018 CP478_RS16585 b29334e83fc6997513db6630cee343b0 414 Pfam PF13439 Glycosyltransferase Family 4 15 204 3.6E-30 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS16585 b29334e83fc6997513db6630cee343b0 414 Pfam PF00534 Glycosyl transferases group 1 213 372 2.8E-43 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS16585 b29334e83fc6997513db6630cee343b0 414 SUPERFAMILY SSF53756 1 390 3.38E-94 T 28-03-2018 CP478_RS16585 b29334e83fc6997513db6630cee343b0 414 Gene3D G3DSA:3.40.50.2000 1 203 4.5E-26 T 28-03-2018 CP478_RS16585 b29334e83fc6997513db6630cee343b0 414 Gene3D G3DSA:3.40.50.2000 204 389 3.8E-45 T 28-03-2018 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 Pfam PF03176 MMPL family 613 943 4.7E-103 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 Pfam PF03176 MMPL family 59 388 6.1E-121 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 TIGRFAM TIGR00833 actII: transport protein 27 935 0.0 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 Gene3D G3DSA:1.20.1640.10 723 932 1.2E-24 T 28-03-2018 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 Gene3D G3DSA:1.20.1640.10 150 359 8.1E-29 T 28-03-2018 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 SUPERFAMILY SSF82866 726 935 1.7E-28 T 28-03-2018 CP478_RS02390 66940788bbfdf2e649dc2a4530cea206 967 SUPERFAMILY SSF82866 160 355 5.89E-28 T 28-03-2018 CP478_RS06185 2c38b06254f8445f695d7ad8bc937acf 526 Pfam PF03972 MmgE/PrpD family 43 496 3.3E-126 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CP478_RS06185 2c38b06254f8445f695d7ad8bc937acf 526 Gene3D G3DSA:1.10.4100.10 32 350 6.2E-76 T 28-03-2018 CP478_RS06185 2c38b06254f8445f695d7ad8bc937acf 526 SUPERFAMILY SSF103378 44 504 3.53E-119 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 Gene3D G3DSA:3.40.250.10 102 223 1.0E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 ProSitePatterns PS00380 Rhodanese signature 1. 144 155 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 Pfam PF12840 Helix-turn-helix domain 17 74 1.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 2.8E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 2.8E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 2.8E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 SUPERFAMILY SSF46785 12 135 7.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 Pfam PF00581 Rhodanese-like domain 121 211 6.6E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 SMART SM00418 17 95 1.7E-25 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 Gene3D G3DSA:1.10.10.10 1 101 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 SUPERFAMILY SSF52821 117 220 3.6E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS01735 5336ee065d5e5bb8af5fb22eac935e9d 226 SMART SM00450 119 215 2.1E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS15445 a8ae961cfa9398d39f3cf3d10f5246ae 314 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 184 299 3.6E-17 T 28-03-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal CP478_RS15445 a8ae961cfa9398d39f3cf3d10f5246ae 314 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 175 300 1.6E-20 T 28-03-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Gene3D G3DSA:1.10.3060.10 630 709 1.6E-28 T 28-03-2018 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Pfam PF01043 SecA preprotein cross-linking domain 232 339 2.5E-35 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Gene3D G3DSA:3.40.50.300 398 629 7.1E-52 T 28-03-2018 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 320 342 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 357 374 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 394 407 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 116 126 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 169 189 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 100 114 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 PRINTS PR00906 SecA protein signature 62 86 2.9E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Pfam PF07517 SecA DEAD-like domain 6 382 8.7E-126 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SUPERFAMILY SSF52540 398 614 1.49E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SUPERFAMILY SSF81886 617 834 1.44E-74 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SMART SM00958 227 339 1.9E-61 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Pfam PF07516 SecA Wing and Scaffold domain 613 833 5.3E-67 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 836 19.729 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 820 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SUPERFAMILY SSF81767 226 349 1.96E-43 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 ProSitePatterns PS01312 SecA family signature. 481 496 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Gene3D G3DSA:3.40.50.300 5 270 1.1E-50 T 28-03-2018 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Gene3D G3DSA:3.40.50.300 287 397 2.8E-9 T 28-03-2018 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 Gene3D G3DSA:3.10.450.50 718 943 2.7E-35 T 28-03-2018 CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SUPERFAMILY SSF52540 4 227 6.01E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SUPERFAMILY SSF52540 349 396 6.01E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17770 dc9e83ed7774481bdaca137e9405cc2c 949 SMART SM00957 2 383 4.6E-275 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 PRINTS PR01228 Eggshell protein signature 244 254 2.0E-5 T 28-03-2018 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 PRINTS PR01228 Eggshell protein signature 219 234 2.0E-5 T 28-03-2018 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 PRINTS PR01228 Eggshell protein signature 132 143 2.0E-5 T 28-03-2018 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 PRINTS PR01228 Eggshell protein signature 268 286 2.0E-5 T 28-03-2018 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 SUPERFAMILY SSF140459 8 84 5.23E-22 T 28-03-2018 CP478_RS01505 e87dc9517cf94d9bf33e1d3ac0092924 837 Pfam PF00934 PE family 1 93 2.4E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS10100 972f12069651aa08dad158ea1b3df945 264 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 53 254 3.4E-67 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CP478_RS10100 972f12069651aa08dad158ea1b3df945 264 SUPERFAMILY SSF161098 9 251 3.27E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS10100 972f12069651aa08dad158ea1b3df945 264 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 30 250 1.8E-88 T 28-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CP478_RS10100 972f12069651aa08dad158ea1b3df945 264 Gene3D G3DSA:1.10.3720.10 42 256 8.3E-34 T 28-03-2018 CP478_RS10100 972f12069651aa08dad158ea1b3df945 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 249 3.6E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 SUPERFAMILY SSF58113 109 237 6.28E-7 T 28-03-2018 CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 Gene3D G3DSA:1.20.5.620 104 129 0.0055 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 Gene3D G3DSA:1.20.5.620 149 211 0.0077 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 Gene3D G3DSA:1.20.5.620 130 148 7.7E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 1.1E-14 T 28-03-2018 IPR019933 DivIVA domain CP478_RS11675 26deb24aebfbf75eea9ebb0537f4b5c7 260 Pfam PF05103 DivIVA protein 3 61 3.1E-12 T 28-03-2018 IPR007793 DivIVA family CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Gene3D G3DSA:2.60.200.20 286 386 6.6E-23 T 28-03-2018 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Pfam PF03704 Bacterial transcriptional activator domain 110 255 9.1E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Gene3D G3DSA:1.10.10.10 1 106 3.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SUPERFAMILY SSF46894 12 103 2.04E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SUPERFAMILY SSF49879 286 381 1.45E-23 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SMART SM00240 307 357 5.5E-14 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 103 2.8E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SUPERFAMILY SSF48452 105 279 1.73E-43 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SMART SM00862 25 103 4.0E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Pfam PF00498 FHA domain 309 371 1.1E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 Gene3D G3DSA:1.25.40.10 107 285 2.3E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS06930 da10c76aca08c5b65b190dfb388dc29c 388 SMART SM01043 110 255 3.6E-54 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CP478_RS00020 adfddfac6808f01e0815b66dcb7890c3 187 Pfam PF05258 Protein of unknown function (DUF721) 75 162 1.7E-23 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CP478_RS00020 adfddfac6808f01e0815b66dcb7890c3 187 Hamap MF_00630 UPF0232 protein . 3 174 33.91 T 28-03-2018 IPR023007 Uncharacterised protein family UPF0232, actinobacteria CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 SMART SM00947 572 743 2.0E-45 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 Pfam PF00916 Sulfate permease family 31 398 1.1E-84 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 Gene3D G3DSA:3.40.1050.10 539 746 1.5E-52 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 Pfam PF00484 Carbonic anhydrase 580 739 1.4E-40 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 SUPERFAMILY SSF53056 519 744 5.49E-47 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS17945 1f9c839940958e05fa399ddc67c1a0c9 764 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 584 591 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:3.40.50.300 802 873 5.0E-4 T 28-03-2018 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 794 816 4.8E-7 T 28-03-2018 IPR030934 Intein C-terminal splicing region CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SUPERFAMILY SSF51294 399 522 5.3E-43 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SUPERFAMILY SSF51294 751 815 5.3E-43 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Pfam PF03796 DnaB-like helicase C terminal domain 201 871 5.5E-96 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 873 3.4E-153 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Pfam PF14528 LAGLIDADG-like domain 615 694 1.2E-14 T 28-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SUPERFAMILY SSF52540 201 403 4.99E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SUPERFAMILY SSF48024 22 133 3.14E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:3.40.50.300 183 405 3.5E-49 T 28-03-2018 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 615 627 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 463 476 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 511 523 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 647 662 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 792 809 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 PRINTS PR00379 Intein signature 810 819 3.0E-18 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:1.10.860.10 16 167 1.2E-52 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:2.170.16.10 406 582 7.9E-29 T 28-03-2018 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:2.170.16.10 714 801 1.7E-14 T 28-03-2018 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SUPERFAMILY SSF55608 601 701 1.59E-16 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SMART SM00305 776 821 5.0E-14 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 400 475 1.0E-10 T 28-03-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SMART SM00306 398 496 1.3E-21 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Pfam PF00772 DnaB-like helicase N terminal domain 23 125 3.0E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Gene3D G3DSA:3.10.28.10 610 711 1.5E-15 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 SMART SM00382 218 411 2.8E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS00315 41c3f73b380e08557f1de55c63d7305e 874 Pfam PF14890 Intein splicing domain 411 815 2.1E-28 T 28-03-2018 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 291 402 1.2E-22 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 Gene3D G3DSA:3.30.420.40 220 447 2.4E-39 T 28-03-2018 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 Gene3D G3DSA:3.30.420.40 1 219 4.3E-22 T 28-03-2018 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 SUPERFAMILY SSF53067 223 443 4.05E-41 T 28-03-2018 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 104 8.0E-9 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 PIRSF PIRSF000538 4 132 1.9E-12 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 PIRSF PIRSF000538 146 443 6.8E-40 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CP478_RS03945 4c0bf5dc8478bd02ac70fa29db2b3dfb 448 SUPERFAMILY SSF53067 6 218 5.67E-24 T 28-03-2018 CP478_RS15825 8b0c05eb84ab0f78a441702bacdd3a28 389 Gene3D G3DSA:3.40.50.450 122 270 3.2E-34 T 28-03-2018 CP478_RS15825 8b0c05eb84ab0f78a441702bacdd3a28 389 Gene3D G3DSA:1.10.10.10 276 373 1.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15825 8b0c05eb84ab0f78a441702bacdd3a28 389 Pfam PF02481 DNA recombination-mediator protein A 70 287 4.6E-70 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CP478_RS15825 8b0c05eb84ab0f78a441702bacdd3a28 389 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 65 295 5.4E-82 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CP478_RS15825 8b0c05eb84ab0f78a441702bacdd3a28 389 SUPERFAMILY SSF102405 100 296 5.04E-34 T 28-03-2018 CP478_RS06565 9617ec0a5c2697ff409be00920e125de 94 Gene3D G3DSA:1.10.287.1060 1 94 1.5E-11 T 28-03-2018 CP478_RS06565 9617ec0a5c2697ff409be00920e125de 94 PIRSF PIRSF037656 1 94 7.5E-58 T 28-03-2018 IPR009416 ESAT-6-like protein, Mycobacterium CP478_RS06565 9617ec0a5c2697ff409be00920e125de 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 8.2E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS06565 9617ec0a5c2697ff409be00920e125de 94 SUPERFAMILY SSF140453 2 93 1.83E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16415 4ae9957ad5e321860768a3978843b836 219 Pfam PF00005 ABC transporter 21 106 9.1E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS16415 4ae9957ad5e321860768a3978843b836 219 Pfam PF03649 Uncharacterised protein family (UPF0014) 112 203 2.3E-31 T 28-03-2018 IPR005226 UPF0014 family CP478_RS16415 4ae9957ad5e321860768a3978843b836 219 Gene3D G3DSA:3.40.50.300 7 161 9.4E-22 T 28-03-2018 CP478_RS16415 4ae9957ad5e321860768a3978843b836 219 SUPERFAMILY SSF52540 8 126 2.13E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF53901 5 125 2.34E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF53901 158 382 2.34E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF53901 416 437 2.34E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.40.47.10 278 443 4.8E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.30.559.10 1018 1212 2.2E-15 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 844 3.7E-81 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SMART SM00825 Beta-ketoacyl synthase 8 441 5.5E-179 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:1.10.1200.10 928 1017 1.8E-20 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 392 501 3.4E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.40.366.10 728 843 5.2E-20 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.40.47.10 2 274 1.1E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.30.70.250 687 727 4.2E-17 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Gene3D G3DSA:3.40.366.10 549 686 3.4E-39 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF00550 Phosphopantetheine attachment site 938 1000 6.6E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF55048 675 733 2.35E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF00698 Acyl transferase domain 551 825 7.1E-47 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF52151 737 830 1.15E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF52151 549 677 1.15E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF00668 Condensation domain 1027 1359 2.7E-26 T 28-03-2018 IPR001242 Condensation domain CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF47336 933 1000 5.5E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF52777 1027 1199 2.45E-19 T 28-03-2018 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 389 3.1E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SMART SM00823 Phosphopantetheine attachment site 936 1004 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 261 4.6E-73 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16035 bfaedd17e3715245d8369ecc7fc34bb9 1488 SUPERFAMILY SSF52777 1209 1456 4.89E-30 T 28-03-2018 CP478_RS19770 1f40af30b81afdad5a627af54fca3dfc 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.9E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19770 1f40af30b81afdad5a627af54fca3dfc 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 5.6E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19770 1f40af30b81afdad5a627af54fca3dfc 98 Gene3D G3DSA:1.10.287.1060 1 98 2.5E-14 T 28-03-2018 CP478_RS19770 1f40af30b81afdad5a627af54fca3dfc 98 SUPERFAMILY SSF140453 4 97 3.79E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS18945 38159869be1e2bdac4ca5853b6278e9e 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.9E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CP478_RS18945 38159869be1e2bdac4ca5853b6278e9e 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.2E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CP478_RS18945 38159869be1e2bdac4ca5853b6278e9e 73 Gene3D G3DSA:2.40.50.140 1 73 7.1E-37 T 28-03-2018 CP478_RS18945 38159869be1e2bdac4ca5853b6278e9e 73 SUPERFAMILY SSF50249 4 72 1.47E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS18945 38159869be1e2bdac4ca5853b6278e9e 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.479 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CP478_RS15260 38587e0db31050a0d783eb94d4e876ba 587 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 322 483 1.5E-8 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS15260 38587e0db31050a0d783eb94d4e876ba 587 Gene3D G3DSA:1.25.40.10 5 240 8.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS15260 38587e0db31050a0d783eb94d4e876ba 587 SUPERFAMILY SSF52540 320 561 1.06E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15260 38587e0db31050a0d783eb94d4e876ba 587 Gene3D G3DSA:3.40.50.300 317 584 1.4E-24 T 28-03-2018 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Hamap MF_00641 Malate synthase G [glcB]. 1 741 399.836 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Gene3D G3DSA:1.10.1860.10 1 88 1.3E-36 T 28-03-2018 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Pfam PF01274 Malate synthase 17 699 6.4E-190 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Gene3D G3DSA:3.20.20.360 89 208 2.8E-25 T 28-03-2018 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Gene3D G3DSA:3.20.20.360 219 590 3.2E-102 T 28-03-2018 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 SUPERFAMILY SSF51645 2 724 6.15E-301 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 724 0.0 T 28-03-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CP478_RS09995 5cc9920f95f72c1645d3c0f9e4bdb1d3 741 Gene3D G3DSA:1.20.1220.12 591 732 5.4E-43 T 28-03-2018 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 ProSitePatterns PS00433 Phosphofructokinase signature. 267 285 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PIRSF PIRSF000532 1 341 6.7E-114 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 Gene3D G3DSA:3.40.50.450 243 333 1.9E-12 T 28-03-2018 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 Pfam PF00365 Phosphofructokinase 2 298 3.2E-103 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 SUPERFAMILY SSF53784 1 333 4.32E-121 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 263 285 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 3.9E-76 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 324 6.0E-139 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 Gene3D G3DSA:3.40.50.450 1 233 9.3E-78 T 28-03-2018 CP478_RS16465 47d25d48c4e3b3858d33bbcd85421704 343 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 343 44.148 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SMART SM00316 121 188 6.2E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SMART SM00316 34 105 3.9E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SMART SM00316 207 277 2.4E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SMART SM00316 292 363 5.8E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Gene3D G3DSA:2.40.50.140 201 283 2.4E-27 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Gene3D G3DSA:2.40.50.140 13 110 1.6E-18 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SUPERFAMILY SSF50249 28 130 1.57E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SUPERFAMILY SSF50249 277 365 2.4E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SUPERFAMILY SSF50249 207 289 2.11E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Gene3D G3DSA:2.40.50.140 120 197 9.6E-12 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 SUPERFAMILY SSF50249 122 202 2.43E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Pfam PF00575 S1 RNA binding domain 291 363 1.2E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Pfam PF00575 S1 RNA binding domain 121 188 3.9E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Pfam PF00575 S1 RNA binding domain 33 105 7.3E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Pfam PF00575 S1 RNA binding domain 206 277 2.1E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 Gene3D G3DSA:2.40.50.140 294 435 1.2E-24 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 229 250 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 102 121 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 346 364 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 143 160 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 54 68 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 172 192 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 126 142 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 307 326 2.0E-88 T 28-03-2018 CP478_RS08915 7a019278d0009c6f8a2c40f7bc604e5b 481 PRINTS PR00681 Ribosomal protein S1 signature 36 54 2.0E-88 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4025 4040 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF47336 3991 4076 5.1E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2584 2875 2.8E-113 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 561 861 1.0E-117 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF53901 2053 2420 2.95E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF50129 3535 3542 2.04E-22 T 28-03-2018 IPR011032 GroES-like CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF50129 3391 3501 2.04E-22 T 28-03-2018 IPR011032 GroES-like CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3710 3890 4.5E-60 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1680 1860 4.5E-60 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.90.180.10 1360 1501 2.0E-36 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.30.70.250 698 741 4.7E-17 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.30.70.250 2722 2758 1.2E-17 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF14765 Polyketide synthase dehydratase 926 1194 4.6E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF14765 Polyketide synthase dehydratase 2940 3215 2.9E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF55048 684 749 3.92E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.47.10 296 458 2.5E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.47.10 2319 2481 2.5E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 1132 1341 5.12E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.50.720 1502 1612 1.9E-16 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 1465 1642 2.96E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF47336 1963 2072 2.75E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 3495 3672 2.22E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00825 Beta-ketoacyl synthase 37 460 1.5E-206 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00825 Beta-ketoacyl synthase 2059 2483 2.1E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.50.720 3704 3967 1.1E-47 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.50.720 1675 1943 1.7E-46 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF55048 2707 2768 7.85E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.366.10 2577 2721 3.1E-50 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.366.10 554 697 5.4E-44 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2057 2304 1.4E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 281 1.2E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 407 5.3E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2312 2430 5.3E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.90.180.10 3387 3703 7.6E-55 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1993 2008 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00826 926 1086 5.7E-78 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00826 2940 3100 6.5E-78 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.366.10 742 852 8.2E-22 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF08659 KR domain 1680 1858 3.6E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF08659 KR domain 3710 3888 3.6E-59 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 1674 1938 6.72E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF52151 750 843 2.88E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF52151 557 686 2.88E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 3223 3369 2.36E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00829 3395 3701 2.2E-170 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00829 1366 1671 5.1E-171 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF51735 3704 3945 5.51E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:1.10.1200.10 3968 4072 3.5E-19 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00550 Phosphopantetheine attachment site 1970 2034 2.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00550 Phosphopantetheine attachment site 4000 4065 7.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:1.10.1200.10 1944 2047 2.8E-20 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1385 1440 7.8E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.90.180.10 1613 1674 0.13 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2217 2233 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00698 Acyl transferase domain 2582 2893 2.9E-60 T 28-03-2018 IPR014043 Acyl transferase CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF00698 Acyl transferase domain 559 880 9.6E-90 T 28-03-2018 IPR014043 Acyl transferase CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF50129 1366 1498 2.52E-25 T 28-03-2018 IPR011032 GroES-like CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.47.10 2049 2316 4.4E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.47.10 28 293 5.3E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF13602 Zinc-binding dehydrogenase 3570 3700 1.9E-19 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF13602 Zinc-binding dehydrogenase 1540 1670 5.6E-18 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Gene3D G3DSA:3.40.366.10 2759 2877 9.8E-28 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00823 Phosphopantetheine attachment site 1966 2038 8.3E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM00823 Phosphopantetheine attachment site 3998 4070 6.0E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF53901 32 397 1.72E-99 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 524 1.2E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2433 2547 1.2E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM01294 1967 2034 1.0E-6 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SMART SM01294 3999 4066 1.3E-6 T 28-03-2018 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF52151 2581 2702 1.1E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS11170 e7f278586e56ec35dc22c5200492a149 4151 SUPERFAMILY SSF52151 2761 2871 1.1E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 443 449 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Pfam PF00403 Heavy-metal-associated domain 18 76 7.6E-11 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 291 305 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 455 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 658 670 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 571 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 592 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 2.1E-25 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 738 4.4E-149 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF55008 11 81 2.36E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Pfam PF00122 E1-E2 ATPase 243 419 1.7E-45 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF81653 246 341 3.14E-18 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 164 737 7.9E-168 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 ProSitePatterns PS01047 Heavy-metal-associated domain. 20 48 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 191 208 9.8E-42 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 109 126 9.8E-42 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 244 263 9.8E-42 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 91 109 9.8E-42 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Gene3D G3DSA:3.40.1110.10 457 558 4.2E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF56784 439 459 7.22E-55 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF56784 494 735 7.22E-55 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Gene3D G3DSA:1.20.1110.10 202 456 6.9E-43 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 214 715 3.5E-80 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Gene3D G3DSA:3.40.50.1000 559 707 1.2E-36 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Pfam PF00702 haloacid dehalogenase-like hydrolase 437 649 1.9E-49 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 Gene3D G3DSA:3.30.70.100 13 84 4.0E-18 T 28-03-2018 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF81665 342 435 1.57E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF81665 684 705 1.57E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00515 477fd59d7e39f206118b6f167f14839b 761 SUPERFAMILY SSF81665 195 244 1.57E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS06600 08961fa57201e733686d5610c2d2a94a 562 Gene3D G3DSA:3.40.50.300 2 162 5.4E-8 T 28-03-2018 CP478_RS06600 08961fa57201e733686d5610c2d2a94a 562 SMART SM00382 15 159 0.0052 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS06600 08961fa57201e733686d5610c2d2a94a 562 SUPERFAMILY SSF52540 8 202 9.56E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06600 08961fa57201e733686d5610c2d2a94a 562 Gene3D G3DSA:1.25.40.10 339 557 2.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 SUPERFAMILY SSF81442 27 538 5.1E-176 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 483 3.8E-149 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 1.5E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 Gene3D G3DSA:1.20.210.10 26 539 5.0E-197 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS16645 7d062ff467f380443b267113f5a4ee24 573 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 535 1.3E-214 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 SMART SM00357 3 67 1.1E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 Gene3D G3DSA:2.40.50.140 1 67 1.3E-28 T 28-03-2018 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 SUPERFAMILY SSF50249 1 66 7.5E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 PIRSF PIRSF002599 1 67 2.2E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CP478_RS19910 6e0519e3915817b5426e133ea67c5aa5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.7E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS17355 a3a6151e753cc97636c84b7afeed4b10 299 SUPERFAMILY SSF53474 6 283 1.62E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17355 a3a6151e753cc97636c84b7afeed4b10 299 Gene3D G3DSA:3.40.50.1820 1 294 1.4E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17355 a3a6151e753cc97636c84b7afeed4b10 299 Pfam PF12146 Serine aminopeptidase, S33 24 258 1.9E-19 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 Pfam PF00934 PE family 1 93 7.4E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 SUPERFAMILY SSF140459 9 84 1.2E-23 T 28-03-2018 CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 PRINTS PR01228 Eggshell protein signature 398 416 1.3E-6 T 28-03-2018 CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 PRINTS PR01228 Eggshell protein signature 363 373 1.3E-6 T 28-03-2018 CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 PRINTS PR01228 Eggshell protein signature 256 267 1.3E-6 T 28-03-2018 CP478_RS06805 5e4361f24229c4d8cc381895424d58c6 562 PRINTS PR01228 Eggshell protein signature 336 351 1.3E-6 T 28-03-2018 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 SUPERFAMILY SSF51419 39 308 2.62E-71 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 243 260 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 Gene3D G3DSA:3.20.20.10 47 292 1.8E-65 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 Gene3D G3DSA:2.40.37.10 293 447 5.1E-40 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 SUPERFAMILY SSF50621 2 45 2.09E-7 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 316 403 1.4E-13 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 87 104 3.4E-26 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 413 435 3.4E-26 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 330 348 3.4E-26 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01181 Diaminopimelate decarboxylase signature 176 185 3.4E-26 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 69 87 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 87 3.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 403 416 3.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 204 217 3.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 89 101 3.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 297 316 3.6E-15 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 SUPERFAMILY SSF50621 289 446 1.0E-54 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 48 306 1.3E-56 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 28 446 39.54 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS07075 6c51fc72558f9c848f5d979a5b2b1f00 447 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 18 446 2.8E-155 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Pfam PF00069 Protein kinase domain 15 262 3.0E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Gene3D G3DSA:1.10.510.10 110 294 6.6E-44 T 28-03-2018 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Gene3D G3DSA:3.30.200.20 7 109 6.5E-21 T 28-03-2018 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 SUPERFAMILY SSF56112 12 276 1.35E-69 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 421 610 1.4E-8 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 SMART SM00220 15 276 5.9E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Gene3D G3DSA:2.120.10.30 503 592 2.3E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Gene3D G3DSA:2.120.10.30 593 664 1.6E-11 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Gene3D G3DSA:2.120.10.30 360 502 3.9E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 SUPERFAMILY SSF101898 423 662 1.57E-47 T 28-03-2018 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 Pfam PF01436 NHL repeat 635 661 4.2E-4 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS05080 4fa381e15ed43d49594da6975fbe3e94 664 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 Gene3D G3DSA:1.10.230.10 285 382 4.4E-34 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 425 1.3E-180 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 Gene3D G3DSA:1.10.580.10 55 284 3.2E-80 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 167 180 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 382 396 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 299 319 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 243 271 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 221 236 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PRINTS PR00143 Citrate synthase signature 362 378 3.2E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 PIRSF PIRSF001369 39 431 1.6E-155 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 Pfam PF00285 Citrate synthase, C-terminal domain 48 414 1.2E-133 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS04890 1994a5f6b7e23d4e9dcea733cac9754b 431 SUPERFAMILY SSF48256 6 431 4.71E-157 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS15870 6fd2d3e3bee7fe20aac5c8e36eba49ae 314 Gene3D G3DSA:3.40.710.10 71 312 1.9E-17 T 28-03-2018 CP478_RS15870 6fd2d3e3bee7fe20aac5c8e36eba49ae 314 SUPERFAMILY SSF56601 85 305 1.75E-18 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 SUPERFAMILY SSF48498 81 231 2.0E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 83 222 5.3E-14 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 Gene3D G3DSA:1.10.10.60 1 57 2.7E-11 T 28-03-2018 CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 Gene3D G3DSA:1.10.357.10 91 246 9.7E-25 T 28-03-2018 CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 SUPERFAMILY SSF46689 10 75 1.69E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS07425 2a0d86cb62a1ccb5280ed185be146a86 261 Gene3D G3DSA:1.10.10.60 58 90 8.5E-6 T 28-03-2018 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 SUPERFAMILY SSF88659 122 185 1.07E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 Pfam PF08281 Sigma-70, region 4 130 181 1.2E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 SUPERFAMILY SSF88946 17 119 1.32E-28 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 183 5.6E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 Gene3D G3DSA:1.10.10.10 137 195 1.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 Gene3D G3DSA:1.10.1740.10 14 136 3.4E-25 T 28-03-2018 CP478_RS21370 1a23de725ebb903b57059e5b5a6433ce 196 Pfam PF04542 Sigma-70 region 2 39 105 3.3E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 SUPERFAMILY SSF89000 289 337 7.85E-15 T 28-03-2018 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 276 334 5.0E-27 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 Gene3D G3DSA:1.10.8.60 281 338 1.9E-25 T 28-03-2018 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 SUPERFAMILY SSF51569 2 269 6.23E-59 T 28-03-2018 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 Pfam PF00682 HMGL-like 7 265 1.4E-49 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 Gene3D G3DSA:3.20.20.70 6 280 5.0E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 343 177.859 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 7 336 5.7E-153 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CP478_RS19320 87a6fe2a24068c0b1a0f5964020ef9fc 346 Pfam PF07836 DmpG-like communication domain 275 335 1.0E-27 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CP478_RS09140 84fbda7bc363df16c399bba2745822f0 310 Gene3D G3DSA:3.90.260.10 151 265 0.0015 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS09140 84fbda7bc363df16c399bba2745822f0 310 Pfam PF01841 Transglutaminase-like superfamily 133 244 6.7E-25 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS09140 84fbda7bc363df16c399bba2745822f0 310 SUPERFAMILY SSF54001 122 278 1.01E-26 T 28-03-2018 CP478_RS09140 84fbda7bc363df16c399bba2745822f0 310 SMART SM00460 177 246 2.2E-21 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS01050 1ab0fab5a56ea53492d80d583ecb54e9 366 Pfam PF03734 L,D-transpeptidase catalytic domain 226 348 1.9E-18 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CP478_RS01050 1ab0fab5a56ea53492d80d583ecb54e9 366 SUPERFAMILY SSF141523 220 348 2.49E-28 T 28-03-2018 CP478_RS01050 1ab0fab5a56ea53492d80d583ecb54e9 366 Gene3D G3DSA:2.40.440.10 222 349 2.1E-24 T 28-03-2018 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 Gene3D G3DSA:3.90.79.10 4 136 3.0E-23 T 28-03-2018 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 PRINTS PR00502 NUDIX hydrolase family signature 46 61 8.2E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 PRINTS PR00502 NUDIX hydrolase family signature 32 46 8.2E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 Pfam PF00293 NUDIX domain 7 124 3.3E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS06375 a79b54848fd5e62b81a14448974d6177 141 SUPERFAMILY SSF55811 5 129 1.18E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS10310 4b3c99081817e5d1b2460eec56a6455a 376 Pfam PF03060 Nitronate monooxygenase 21 311 1.7E-43 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS10310 4b3c99081817e5d1b2460eec56a6455a 376 SUPERFAMILY SSF51412 98 336 5.8E-47 T 28-03-2018 CP478_RS10310 4b3c99081817e5d1b2460eec56a6455a 376 SUPERFAMILY SSF51412 22 58 5.8E-47 T 28-03-2018 CP478_RS10310 4b3c99081817e5d1b2460eec56a6455a 376 Gene3D G3DSA:3.20.20.70 1 375 1.5E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 Pfam PF00156 Phosphoribosyl transferase domain 9 193 1.0E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 Pfam PF01738 Dienelactone hydrolase family 243 426 1.9E-5 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 Gene3D G3DSA:3.40.50.2020 2 212 1.4E-33 T 28-03-2018 CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 SUPERFAMILY SSF53271 3 210 4.98E-50 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 Gene3D G3DSA:3.40.50.1820 219 436 3.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03060 2fce814870edd0cdf67758d370647d73 443 SUPERFAMILY SSF53474 229 436 1.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18715 df79e657a5c6f4d51f29467b4a5a1d92 158 SUPERFAMILY SSF55729 4 140 2.33E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS18715 df79e657a5c6f4d51f29467b4a5a1d92 158 Pfam PF00583 Acetyltransferase (GNAT) family 33 130 3.1E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS18715 df79e657a5c6f4d51f29467b4a5a1d92 158 Gene3D G3DSA:3.40.630.30 1 153 7.1E-37 T 28-03-2018 CP478_RS18715 df79e657a5c6f4d51f29467b4a5a1d92 158 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 17 150 2.8E-42 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CP478_RS18510 095fbd2372884bf7e88bf5454db0f5bb 81 Gene3D G3DSA:3.40.50.970 1 81 5.4E-15 T 28-03-2018 CP478_RS18510 095fbd2372884bf7e88bf5454db0f5bb 81 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 62 1.2E-18 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS18510 095fbd2372884bf7e88bf5454db0f5bb 81 ProSitePatterns PS00801 Transketolase signature 1. 26 45 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS18510 095fbd2372884bf7e88bf5454db0f5bb 81 SUPERFAMILY SSF52518 4 62 2.36E-7 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 Gene3D G3DSA:3.40.50.980 31 202 9.8E-26 T 28-03-2018 CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 Pfam PF00501 AMP-binding enzyme 68 506 3.4E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 SUPERFAMILY SSF56801 34 614 2.49E-85 T 28-03-2018 CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 Gene3D G3DSA:3.40.50.980 203 370 1.9E-20 T 28-03-2018 CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 Gene3D G3DSA:3.30.300.30 503 612 3.8E-14 T 28-03-2018 CP478_RS10475 454c29eedc94fc0f0c14f83d8857b0d1 620 Gene3D G3DSA:2.30.38.10 403 501 7.8E-21 T 28-03-2018 CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 21 200 1.3E-63 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 Pfam PF00625 Guanylate kinase 22 200 6.7E-40 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 SUPERFAMILY SSF52540 21 201 2.7E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 Gene3D G3DSA:3.40.50.300 14 202 9.6E-54 T 28-03-2018 CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 ProSitePatterns PS00856 Guanylate kinase-like signature. 55 72 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 SMART SM00072 20 204 1.3E-76 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CP478_RS07615 84ce26f87cba4f7a77ee6bb219673b3c 208 Hamap MF_00328 Guanylate kinase [gmk]. 19 204 34.548 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CP478_RS16395 69a2f36f6c1ac1559f778e26dbe64f29 66 Pfam PF04255 Protein of unknown function (DUF433) 6 61 7.7E-23 T 28-03-2018 IPR007367 Protein of unknown function DUF433 CP478_RS16395 69a2f36f6c1ac1559f778e26dbe64f29 66 SUPERFAMILY SSF46689 3 63 1.4E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16395 69a2f36f6c1ac1559f778e26dbe64f29 66 Gene3D G3DSA:1.10.10.10 6 64 8.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 Gene3D G3DSA:3.40.50.360 8 139 1.2E-25 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 SUPERFAMILY SSF52218 7 139 2.32E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 PIRSF PIRSF005087 6 144 9.5E-56 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 TIGRFAM TIGR00333 nrdI: nrdI protein 9 138 1.3E-47 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 Pfam PF07972 NrdI Flavodoxin like 9 130 5.4E-46 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CP478_RS16695 13c89fb2530a856a5235d7baec24d60d 150 Hamap MF_00128 Protein NrdI [nrdI]. 7 140 35.406 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 SUPERFAMILY SSF47323 674 898 2.99E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 849 6.0E-245 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 7 1037 13.87 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 SUPERFAMILY SSF50677 209 391 8.06E-48 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 653 8.2E-180 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Gene3D G3DSA:1.10.730.10 616 834 1.2E-48 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Gene3D G3DSA:3.40.50.620 34 201 4.7E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 53 64 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Gene3D G3DSA:3.40.50.620 409 615 8.5E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 SUPERFAMILY SSF52374 14 203 9.55E-128 T 28-03-2018 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 SUPERFAMILY SSF52374 411 651 9.55E-128 T 28-03-2018 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Pfam PF08264 Anticodon-binding domain of tRNA 701 840 1.7E-23 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 235 258 1.4E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 538 551 1.4E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 578 587 1.4E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 46 57 1.4E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 409 424 1.4E-31 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CP478_RS08420 9fcc3443b80a4618209ff8acf60d4562 1041 Gene3D G3DSA:3.90.740.10 202 408 2.0E-63 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 SUPERFAMILY SSF51971 368 415 1.02E-46 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 SUPERFAMILY SSF51971 112 319 1.02E-46 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Pfam PF00037 4Fe-4S binding domain 40 61 3.9E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 PRINTS PR00419 Adrenodoxin reductase family signature 253 267 2.8E-19 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 PRINTS PR00419 Adrenodoxin reductase family signature 138 151 2.8E-19 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 PRINTS PR00419 Adrenodoxin reductase family signature 181 191 2.8E-19 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 PRINTS PR00419 Adrenodoxin reductase family signature 114 136 2.8E-19 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Gene3D G3DSA:3.40.50.720 103 207 4.1E-9 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 115 275 1.0E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Gene3D G3DSA:3.50.50.60 208 415 1.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 SUPERFAMILY SSF54862 1 87 1.52E-16 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Gene3D G3DSA:3.30.70.20 1 47 1.4E-12 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 Gene3D G3DSA:3.30.70.20 48 102 6.8E-7 T 28-03-2018 CP478_RS04830 9d597720034754df752a95c0dfb081aa 575 PIRSF PIRSF000362 107 549 3.0E-128 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 Gene3D G3DSA:3.40.50.300 332 569 4.5E-64 T 28-03-2018 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 Pfam PF00005 ABC transporter 352 501 3.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 SUPERFAMILY SSF90123 6 321 7.06E-67 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 SUPERFAMILY SSF52540 326 572 1.95E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 SMART SM00382 361 548 1.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 Pfam PF00664 ABC transporter transmembrane region 18 288 4.3E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS06965 e7ab7c8d9c9af7bf5fdcdc6cb92dc4aa 582 Gene3D G3DSA:1.20.1560.10 2 316 3.6E-67 T 28-03-2018 CP478_RS16270 7bb110802686eb0773805c6f4013f506 64 Pfam PF00830 Ribosomal L28 family 4 60 4.7E-23 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS16270 7bb110802686eb0773805c6f4013f506 64 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.6E-24 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS16270 7bb110802686eb0773805c6f4013f506 64 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 64 18.015 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS16270 7bb110802686eb0773805c6f4013f506 64 SUPERFAMILY SSF143800 1 63 8.24E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS16270 7bb110802686eb0773805c6f4013f506 64 Gene3D G3DSA:2.30.170.40 2 64 4.0E-22 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS14830 3f19f30e1c96e18a1c8a0edae65ee022 129 SUPERFAMILY SSF56399 9 115 2.5E-27 T 28-03-2018 CP478_RS14830 3f19f30e1c96e18a1c8a0edae65ee022 129 Pfam PF06108 Protein of unknown function (DUF952) 16 103 7.1E-26 T 28-03-2018 IPR009297 Protein of unknown function DUF952 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 99 20.691 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 Gene3D G3DSA:2.30.30.30 1 93 7.6E-34 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 SMART SM00739 2 29 1.5E-5 T 28-03-2018 IPR005824 KOW CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 Pfam PF00467 KOW motif 5 36 3.5E-11 T 28-03-2018 IPR005824 KOW CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 105 1.2E-23 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 105 1.3E-37 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03875 c2717f80de5e4f510420e2d434bb0fdf 105 SUPERFAMILY SSF50104 1 102 2.11E-30 T 28-03-2018 IPR008991 Translation protein SH3-like domain CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 292 30.904 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 PIRSF PIRSF010376 4 300 5.9E-81 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 Pfam PF08544 GHMP kinases C terminal 207 278 6.9E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 SUPERFAMILY SSF54211 5 159 4.17E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 Pfam PF00288 GHMP kinases N terminal domain 91 148 2.4E-8 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 SUPERFAMILY SSF55060 167 287 1.35E-19 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 Gene3D G3DSA:3.30.230.10 6 163 7.3E-47 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 274 5.3E-52 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CP478_RS05530 792da81eca07e1503a7be92915b8c779 306 Gene3D G3DSA:3.30.70.890 164 294 1.9E-27 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 SUPERFAMILY SSF64005 63 289 1.57E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 Gene3D G3DSA:3.40.1180.10 54 296 1.2E-85 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 67 294 5.3E-75 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 240 257 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 Pfam PF01255 Putative undecaprenyl diphosphate synthase 74 294 4.1E-73 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS12880 b78d2b183c399e0d163c297fbf0bbcb3 296 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 67 295 37.843 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS06130 92236d6b0e4dfca6967be24a35adbe0e 286 Gene3D G3DSA:3.90.1720.10 65 261 2.3E-21 T 28-03-2018 CP478_RS06130 92236d6b0e4dfca6967be24a35adbe0e 286 SUPERFAMILY SSF54001 67 187 3.04E-26 T 28-03-2018 CP478_RS06130 92236d6b0e4dfca6967be24a35adbe0e 286 SUPERFAMILY SSF54001 228 285 3.04E-26 T 28-03-2018 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 184 1.1E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 Pfam PF04545 Sigma-70, region 4 133 182 2.6E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 Pfam PF04542 Sigma-70 region 2 29 96 3.0E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 Gene3D G3DSA:1.10.10.10 95 187 8.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 SUPERFAMILY SSF88659 121 184 5.61E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 SUPERFAMILY SSF88946 10 97 4.32E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS02365 776833c54b74ce51055476955ec0d9e8 187 Gene3D G3DSA:1.10.1740.10 10 94 1.8E-18 T 28-03-2018 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Gene3D G3DSA:3.40.50.980 59 205 7.7E-28 T 28-03-2018 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Gene3D G3DSA:2.30.38.10 206 273 2.4E-6 T 28-03-2018 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Gene3D G3DSA:3.40.50.980 9 58 2.0E-6 T 28-03-2018 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 ProSitePatterns PS00455 Putative AMP-binding domain signature. 54 65 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Pfam PF00501 AMP-binding enzyme 48 279 9.0E-28 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Gene3D G3DSA:3.30.300.30 274 380 1.1E-22 T 28-03-2018 CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 Pfam PF13193 AMP-binding enzyme C-terminal domain 289 364 3.3E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS02905 a1acef6571049dee96048f4250fa0cbb 380 SUPERFAMILY SSF56801 48 377 7.72E-66 T 28-03-2018 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 SUPERFAMILY SSF52402 25 226 1.15E-39 T 28-03-2018 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 Pfam PF09179 TilS substrate binding domain 246 304 5.1E-10 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 10 308 18.111 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 SUPERFAMILY SSF82829 206 304 9.42E-14 T 28-03-2018 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 Pfam PF01171 PP-loop family 29 193 1.2E-28 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 Gene3D G3DSA:3.40.50.620 25 230 4.7E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS19795 a740e1b5133972d79321e095a3d81fd0 323 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 29 197 3.0E-33 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CP478_RS04335 cd6790497f4a0132109cd0f1ce4a5f66 265 Pfam PF04454 Encapsulating protein for peroxidase 1 251 2.6E-95 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CP478_RS04335 cd6790497f4a0132109cd0f1ce4a5f66 265 PIRSF PIRSF019254 1 265 5.8E-93 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 SUPERFAMILY SSF57716 232 267 2.72E-12 T 28-03-2018 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 Pfam PF06827 Zinc finger found in FPG and IleRS 240 267 4.2E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 126 213 4.8E-25 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 SMART SM00898 2 112 9.3E-17 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 Gene3D G3DSA:1.10.8.50 120 268 7.8E-46 T 28-03-2018 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 SMART SM01232 126 218 3.6E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 Gene3D G3DSA:3.20.190.10 2 119 2.5E-19 T 28-03-2018 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 SUPERFAMILY SSF81624 2 127 1.04E-22 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS13470 92df5fbdef0124760e6cd07733b50014 268 SUPERFAMILY SSF46946 125 209 1.21E-23 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 SUPERFAMILY SSF53448 8 229 5.63E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 Gene3D G3DSA:3.90.550.10 3 231 4.3E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 103 110 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 228 7.0E-70 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 230 2.6E-87 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CP478_RS19575 eb86c513f8c4338c0a54d8dace4bc616 231 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 229 41.641 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CP478_RS08145 a57f65adc38ef382fef7f2e21c288eb2 144 SUPERFAMILY SSF141322 77 141 1.05E-6 T 28-03-2018 CP478_RS08145 a57f65adc38ef382fef7f2e21c288eb2 144 Gene3D G3DSA:2.40.50.140 69 142 4.1E-17 T 28-03-2018 CP478_RS08145 a57f65adc38ef382fef7f2e21c288eb2 144 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 142 1.8E-29 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 SUPERFAMILY SSF46689 6 71 7.18E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 Gene3D G3DSA:1.10.260.40 37 80 5.5E-13 T 28-03-2018 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 Gene3D G3DSA:1.10.10.60 3 36 5.6E-12 T 28-03-2018 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 Gene3D G3DSA:1.10.357.10 81 189 0.001 T 28-03-2018 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 SUPERFAMILY SSF48498 79 184 6.67E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS12240 cf1ac1423df53baa207595f5ca539e78 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 4.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 SUPERFAMILY SSF52777 60 150 4.34E-6 T 28-03-2018 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 Gene3D G3DSA:3.30.559.10 68 154 7.6E-6 T 28-03-2018 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 1 445 5.1E-162 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 Pfam PF06974 Protein of unknown function (DUF1298) 297 442 2.7E-39 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 SUPERFAMILY SSF52777 234 442 4.67E-5 T 28-03-2018 CP478_RS20425 410fbad8f8503cde6f9db17f95b1179d 448 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 1 257 1.4E-96 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS06955 9c43d1667ac3b38f26667895578ea206 113 Gene3D G3DSA:3.40.1190.20 11 109 8.6E-4 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS06955 9c43d1667ac3b38f26667895578ea206 113 Pfam PF05305 Protein of unknown function (DUF732) 19 109 4.6E-23 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 Gene3D G3DSA:2.40.50.140 1 81 2.0E-29 T 28-03-2018 CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 SUPERFAMILY SSF50249 1 79 9.77E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 Pfam PF02565 Recombination protein O C terminal 86 237 5.3E-31 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 Pfam PF11967 Recombination protein O N terminal 1 79 2.5E-27 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 SUPERFAMILY SSF57863 82 232 3.4E-35 T 28-03-2018 CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 181 6.6E-29 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CP478_RS12885 7c053f30c10334eb5a45af2cb9dbb52b 265 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 25.408 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Pfam PF03176 MMPL family 601 939 8.6E-101 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Pfam PF03176 MMPL family 53 381 9.2E-113 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Gene3D G3DSA:1.20.58.70 588 681 0.024 T 28-03-2018 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 TIGRFAM TIGR00833 actII: transport protein 21 928 7.3E-301 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 SUPERFAMILY SSF82866 149 349 1.44E-25 T 28-03-2018 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 SUPERFAMILY SSF82866 719 928 1.2E-29 T 28-03-2018 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Gene3D G3DSA:1.20.5.50 481 567 0.0013 T 28-03-2018 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Gene3D G3DSA:1.20.1640.10 717 929 2.3E-25 T 28-03-2018 CP478_RS02145 f5f98eadcc889194c9ea115745bf30b6 958 Gene3D G3DSA:1.20.1640.10 141 366 1.8E-27 T 28-03-2018 CP478_RS13360 543981e585960c5187b60b66990233a2 953 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 351 766 6.9E-159 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CP478_RS13360 543981e585960c5187b60b66990233a2 953 SUPERFAMILY SSF50249 376 459 4.8E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS13360 543981e585960c5187b60b66990233a2 953 Pfam PF10150 Ribonuclease E/G family 455 736 9.0E-101 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CP478_RS13360 543981e585960c5187b60b66990233a2 953 SMART SM00316 374 453 2.3E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS13360 543981e585960c5187b60b66990233a2 953 Gene3D G3DSA:2.40.50.140 369 458 3.8E-26 T 28-03-2018 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 309 320 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 160 173 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 37 51 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 361 378 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 332 346 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PRINTS PR00148 Enolase signature 106 122 1.6E-48 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 PIRSF PIRSF001400 2 422 3.5E-186 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 SMART SM01193 4 133 1.1E-86 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 ProSitePatterns PS00164 Enolase signature. 332 345 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 Gene3D G3DSA:3.30.390.10 3 126 3.8E-50 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 418 1.5E-124 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 Gene3D G3DSA:3.20.20.120 127 429 4.3E-99 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 SUPERFAMILY SSF51604 137 418 3.13E-122 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 Hamap MF_00318 Enolase [eno]. 2 409 45.293 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 SUPERFAMILY SSF54826 3 137 4.84E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 SMART SM01192 138 423 1.2E-205 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 Pfam PF03952 Enolase, N-terminal domain 4 133 5.1E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS05600 dd5bc7bb25f01c13bc49a2c1144639bf 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 4.2E-205 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 Pfam PF03065 Glycosyl hydrolase family 57 14 280 2.3E-19 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 Pfam PF09210 Domain of unknown function (DUF1957) 444 522 1.0E-19 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 Gene3D G3DSA:1.20.1430.10 407 526 1.5E-33 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 SUPERFAMILY SSF88713 10 405 1.22E-99 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 Gene3D G3DSA:3.20.110.10 8 405 2.5E-81 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CP478_RS16580 d1c30827af477b8e6e5ac0cad8d6c620 526 SUPERFAMILY SSF88688 400 525 5.23E-21 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CP478_RS10775 133911f16a12534c7dffe7976af2fda2 228 Gene3D G3DSA:3.90.640.20 128 228 1.5E-8 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CP478_RS10775 133911f16a12534c7dffe7976af2fda2 228 Pfam PF11738 Protein of unknown function (DUF3298) 147 221 2.0E-15 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 Gene3D G3DSA:3.30.70.1450 147 220 2.8E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 Pfam PF02080 TrkA-C domain 149 216 2.2E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 SUPERFAMILY SSF116726 133 215 5.1E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 Gene3D G3DSA:3.40.50.720 1 146 2.3E-27 T 28-03-2018 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.6E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 PRINTS PR00335 TrkA potassium uptake protein signature 48 58 3.6E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.6E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 3.6E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 Pfam PF02254 TrkA-N domain 3 118 1.8E-27 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CP478_RS14765 032e1fac8dec5a487e98eb86890d5af4 220 SUPERFAMILY SSF51735 1 145 2.25E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Gene3D G3DSA:1.10.10.60 188 255 1.6E-10 T 28-03-2018 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Gene3D G3DSA:1.10.10.60 2 53 1.3E-19 T 28-03-2018 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Gene3D G3DSA:1.10.357.10 288 386 6.5E-6 T 28-03-2018 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 7.6E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Pfam PF00440 Bacterial regulatory proteins, tetR family 223 269 6.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 SUPERFAMILY SSF46689 7 75 7.48E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 SUPERFAMILY SSF46689 219 288 4.77E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Gene3D G3DSA:1.10.10.60 54 160 1.6E-8 T 28-03-2018 CP478_RS10680 d570397131afc8b6be223fbe470ee917 406 Gene3D G3DSA:1.10.10.60 256 287 1.9E-5 T 28-03-2018 CP478_RS17245 60410184d9c69860b2a7e6f818621163 252 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 145 163 - T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17245 60410184d9c69860b2a7e6f818621163 252 Gene3D G3DSA:3.40.30.10 106 195 3.2E-15 T 28-03-2018 CP478_RS17245 60410184d9c69860b2a7e6f818621163 252 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 45 187 2.2E-48 T 28-03-2018 CP478_RS17245 60410184d9c69860b2a7e6f818621163 252 SUPERFAMILY SSF52833 43 194 6.93E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS17245 60410184d9c69860b2a7e6f818621163 252 PIRSF PIRSF000216 18 246 5.5E-77 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS19960 69a54ef5dfd71ea90a6ec82705aab46c 191 Pfam PF00482 Type II secretion system (T2SS), protein F 46 172 3.8E-14 T 28-03-2018 IPR018076 Type II secretion system F domain CP478_RS15895 0038b450f3dc7ee5b1df0590fdd487ba 147 SUPERFAMILY SSF54427 12 143 5.35E-35 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS15895 0038b450f3dc7ee5b1df0590fdd487ba 147 Gene3D G3DSA:3.10.450.50 5 140 1.8E-33 T 28-03-2018 CP478_RS15895 0038b450f3dc7ee5b1df0590fdd487ba 147 Pfam PF13577 SnoaL-like domain 14 137 4.8E-30 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS05735 d378fa21295c4eeac6ab10f740e0840d 415 Pfam PF00872 Transposase, Mutator family 1 379 5.4E-154 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS05735 d378fa21295c4eeac6ab10f740e0840d 415 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS17050 d378fa21295c4eeac6ab10f740e0840d 415 Pfam PF00872 Transposase, Mutator family 1 379 5.4E-154 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS17050 d378fa21295c4eeac6ab10f740e0840d 415 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS16535 d378fa21295c4eeac6ab10f740e0840d 415 Pfam PF00872 Transposase, Mutator family 1 379 5.4E-154 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS16535 d378fa21295c4eeac6ab10f740e0840d 415 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS13580 e58fdb62fbefbde10a6d682440df147e 491 Gene3D G3DSA:3.30.559.10 13 193 4.0E-9 T 28-03-2018 CP478_RS13580 e58fdb62fbefbde10a6d682440df147e 491 SUPERFAMILY SSF52777 39 177 1.22E-12 T 28-03-2018 CP478_RS13580 e58fdb62fbefbde10a6d682440df147e 491 Pfam PF06974 Protein of unknown function (DUF1298) 321 460 8.9E-12 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS13580 e58fdb62fbefbde10a6d682440df147e 491 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 8 282 6.1E-85 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS13580 e58fdb62fbefbde10a6d682440df147e 491 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 14 464 6.7E-125 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 3.2E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Gene3D G3DSA:1.20.140.10 226 385 2.5E-48 T 28-03-2018 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 SUPERFAMILY SSF47203 234 384 3.38E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Gene3D G3DSA:2.40.110.10 128 225 1.2E-37 T 28-03-2018 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Gene3D G3DSA:1.10.540.10 3 127 9.5E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 SUPERFAMILY SSF56645 9 248 3.14E-81 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 1.0E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS14925 26cc9b97798fb32afe889cea946fe766 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 1.5E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 SUPERFAMILY SSF51690 117 285 1.22E-54 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 Gene3D G3DSA:3.20.20.70 143 275 9.1E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 SUPERFAMILY SSF54675 8 116 3.53E-27 T 28-03-2018 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 PIRSF PIRSF006250 5 285 9.5E-108 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 285 3.5E-98 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 284 7.0E-62 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 115 8.6E-20 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CP478_RS08735 87f385ae29a0a6c055b62b0be543ebe6 285 Gene3D G3DSA:3.90.1170.20 4 142 3.1E-40 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Gene3D G3DSA:3.40.228.10 232 649 6.3E-94 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Gene3D G3DSA:2.20.25.90 65 108 7.7E-28 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 76 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 773 790 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Pfam PF00384 Molybdopterin oxidoreductase 118 828 6.5E-133 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Gene3D G3DSA:3.40.50.740 118 224 2.3E-4 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Gene3D G3DSA:2.40.40.20 1045 1232 6.6E-43 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Pfam PF01568 Molydopterin dinucleotide binding domain 1086 1195 3.7E-21 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 19 1226 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 Gene3D G3DSA:3.40.50.740 650 786 2.9E-29 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 SMART SM00926 53 115 5.6E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 SUPERFAMILY SSF53706 15 1064 0.0 T 28-03-2018 CP478_RS06380 631fd6c3940729d779b2e85b08de3b9a 1232 SUPERFAMILY SSF50692 1086 1226 3.39E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 7.6E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 7.6E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 7.6E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 Gene3D G3DSA:1.10.10.10 18 115 6.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 SMART SM00418 34 114 3.9E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 Pfam PF01022 Bacterial regulatory protein, arsR family 41 90 4.0E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14460 f63db1b1ef8d2632b8102336a9c34d4e 119 SUPERFAMILY SSF46785 15 118 3.01E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18565 1ecd43f8053337ce7c78f954aeb0e23e 287 PIRSF PIRSF003085 2 287 1.0E-117 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS18565 1ecd43f8053337ce7c78f954aeb0e23e 287 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 283 1.5E-126 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18565 1ecd43f8053337ce7c78f954aeb0e23e 287 Gene3D G3DSA:3.40.50.150 2 287 2.1E-59 T 28-03-2018 CP478_RS18565 1ecd43f8053337ce7c78f954aeb0e23e 287 SUPERFAMILY SSF53335 13 287 2.05E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 589 31.71 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 SUPERFAMILY SSF55261 292 414 1.46E-33 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 SUPERFAMILY SSF50249 5 109 1.52E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Pfam PF02938 GAD domain 315 395 2.7E-12 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 523 537 1.6E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.6E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.6E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 479 495 1.6E-25 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 562 3.0E-99 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 SUPERFAMILY SSF55681 419 588 1.89E-96 T 28-03-2018 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 SUPERFAMILY SSF55681 117 295 1.89E-96 T 28-03-2018 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Gene3D G3DSA:2.40.50.140 3 112 3.8E-25 T 28-03-2018 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 587 2.6E-202 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Gene3D G3DSA:3.30.930.10 135 591 2.5E-97 T 28-03-2018 CP478_RS14100 67b1decd46ae980dfa82407632225f78 596 Pfam PF01336 OB-fold nucleic acid binding domain 21 106 8.9E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 60 74 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 Pfam PF00825 Ribonuclease P 12 117 4.9E-23 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 12 115 6.0E-23 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 SUPERFAMILY SSF54211 11 120 1.06E-22 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 11 120 14.7 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CP478_RS21435 f2a3f61ed7bb5583f483e757bc4674b8 125 Gene3D G3DSA:3.30.230.10 8 125 1.1E-24 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS00395 972850fd8c97fa32f49af3af1c18c5a6 235 Gene3D G3DSA:3.30.70.270 93 232 2.7E-7 T 28-03-2018 CP478_RS00395 972850fd8c97fa32f49af3af1c18c5a6 235 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 174 1.3E-17 T 28-03-2018 IPR000477 Reverse transcriptase domain CP478_RS00395 972850fd8c97fa32f49af3af1c18c5a6 235 SUPERFAMILY SSF56672 11 176 2.56E-24 T 28-03-2018 CP478_RS15705 9d1f47d1aeb7b590a14ded6144673441 220 SMART SM00554 123 218 2.2E-29 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15705 9d1f47d1aeb7b590a14ded6144673441 220 Pfam PF02469 Fasciclin domain 95 217 2.2E-26 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15705 9d1f47d1aeb7b590a14ded6144673441 220 SUPERFAMILY SSF82153 62 218 1.29E-36 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15705 9d1f47d1aeb7b590a14ded6144673441 220 Gene3D G3DSA:2.30.180.10 82 219 4.9E-26 T 28-03-2018 IPR000782 FAS1 domain CP478_RS17710 2d9437043f4632d24df85d46a7881c91 330 SUPERFAMILY SSF52540 113 289 2.63E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17710 2d9437043f4632d24df85d46a7881c91 330 Pfam PF03193 RsgA GTPase 97 267 2.3E-40 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CP478_RS17710 2d9437043f4632d24df85d46a7881c91 330 Gene3D G3DSA:1.10.40.50 268 330 6.9E-11 T 28-03-2018 CP478_RS17710 2d9437043f4632d24df85d46a7881c91 330 Gene3D G3DSA:3.40.50.300 110 267 7.2E-18 T 28-03-2018 CP478_RS17710 2d9437043f4632d24df85d46a7881c91 330 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 307 1.5E-38 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 150 511 9.6E-51 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 SUPERFAMILY SSF53850 85 588 2.79E-83 T 28-03-2018 CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 Gene3D G3DSA:3.40.190.10 253 346 5.4E-19 T 28-03-2018 CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 Gene3D G3DSA:3.10.105.10 347 561 1.1E-44 T 28-03-2018 CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 Gene3D G3DSA:3.90.76.10 99 247 4.7E-14 T 28-03-2018 CP478_RS07000 cbb141bacfb72019b056424c2ccfa9e6 591 PIRSF PIRSF002741 38 586 6.1E-51 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CP478_RS03515 77599c08630d10003b215444f968c651 178 SUPERFAMILY SSF160369 1 169 3.14E-49 T 28-03-2018 CP478_RS03515 77599c08630d10003b215444f968c651 178 Pfam PF00466 Ribosomal protein L10 1 98 8.6E-26 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CP478_RS03515 77599c08630d10003b215444f968c651 178 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.695 T 28-03-2018 IPR022973 Ribosomal protein L10 CP478_RS03515 77599c08630d10003b215444f968c651 178 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 SUPERFAMILY SSF63418 55 141 2.49E-16 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Gene3D G3DSA:3.40.1190.10 142 378 3.6E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 SUPERFAMILY SSF53244 374 529 1.83E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 SUPERFAMILY SSF53623 142 371 2.09E-68 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 60 528 3.6E-163 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Gene3D G3DSA:3.90.190.20 379 535 3.0E-47 T 28-03-2018 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Pfam PF02875 Mur ligase family, glutamate ligase domain 374 458 4.8E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Gene3D G3DSA:3.40.1390.10 32 141 3.4E-24 T 28-03-2018 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 34 528 32.462 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Pfam PF01225 Mur ligase family, catalytic domain 61 138 1.8E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CP478_RS11740 a7a5e9475071b341cbc1bf30e1a9dd33 535 Pfam PF08245 Mur ligase middle domain 151 354 3.3E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 PIRSF PIRSF004491 6 331 6.6E-94 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 25 328 1.2E-68 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 Pfam PF06574 FAD synthetase 20 167 4.9E-51 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 SUPERFAMILY SSF52374 23 186 4.5E-30 T 28-03-2018 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 Gene3D G3DSA:3.40.50.620 8 190 3.3E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 SUPERFAMILY SSF82114 185 329 9.37E-39 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 Pfam PF01687 Riboflavin kinase 195 328 1.6E-33 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 Gene3D G3DSA:2.40.30.30 191 331 7.2E-41 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CP478_RS15255 d40184aaea69a40a1f6e8475ea72a386 331 SMART SM00904 194 329 1.7E-49 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 SUPERFAMILY SSF56425 317 495 7.59E-34 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 SUPERFAMILY SSF51905 212 321 2.35E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 SUPERFAMILY SSF51905 3 153 2.35E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 SUPERFAMILY SSF51905 500 559 2.35E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 Pfam PF00890 FAD binding domain 7 541 1.2E-90 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 Gene3D G3DSA:3.50.50.60 405 558 3.7E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 Gene3D G3DSA:3.50.50.60 1 389 1.8E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.3E-7 T 28-03-2018 CP478_RS19335 0c793c55dd4a439f789e73856443a031 563 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 205 230 4.3E-7 T 28-03-2018 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 21 78 2.4E-12 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 SUPERFAMILY SSF55124 6 84 1.05E-20 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 7 358 7.0E-93 T 28-03-2018 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like CP478_RS11255 00a4db78334489125f582847ee5a0062 363 Gene3D G3DSA:3.30.413.10 295 360 0.0078 T 28-03-2018 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 Gene3D G3DSA:3.90.480.10 24 197 1.2E-29 T 28-03-2018 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 Gene3D G3DSA:3.90.480.10 198 294 9.6E-17 T 28-03-2018 CP478_RS11255 00a4db78334489125f582847ee5a0062 363 SUPERFAMILY SSF55124 174 291 2.47E-19 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.9E-67 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.2E-42 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 SUPERFAMILY SSF50249 2 123 7.28E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 4.6E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.616 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 PIRSF PIRSF002133 1 124 5.3E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03685 22e39403efec9c5a767f38bf33b44718 124 Gene3D G3DSA:2.40.50.140 1 124 6.7E-63 T 28-03-2018 CP478_RS12210 61ad67aff7a0bc11740e01f2b925ab7c 115 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 79 3.0E-17 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CP478_RS12210 61ad67aff7a0bc11740e01f2b925ab7c 115 Pfam PF00550 Phosphopantetheine attachment site 12 77 5.0E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12210 61ad67aff7a0bc11740e01f2b925ab7c 115 SUPERFAMILY SSF47336 3 110 9.81E-27 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12210 61ad67aff7a0bc11740e01f2b925ab7c 115 Gene3D G3DSA:1.10.1200.10 1 115 2.6E-25 T 28-03-2018 CP478_RS12210 61ad67aff7a0bc11740e01f2b925ab7c 115 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.462 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CP478_RS09340 1864006850fe0cd4260ec87813f74ab4 230 Hamap MF_00238 Cytidylate kinase [cmk]. 7 226 32.391 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CP478_RS09340 1864006850fe0cd4260ec87813f74ab4 230 Pfam PF02224 Cytidylate kinase 9 223 5.1E-82 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CP478_RS09340 1864006850fe0cd4260ec87813f74ab4 230 Gene3D G3DSA:3.40.50.300 4 225 4.2E-46 T 28-03-2018 CP478_RS09340 1864006850fe0cd4260ec87813f74ab4 230 SUPERFAMILY SSF52540 8 224 6.19E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09340 1864006850fe0cd4260ec87813f74ab4 230 TIGRFAM TIGR00017 cmk: cytidylate kinase 7 220 3.7E-67 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CP478_RS14890 25bd410c95c0ec0e76142b707074eaf6 164 SUPERFAMILY SSF50814 4 163 3.07E-47 T 28-03-2018 IPR012674 Calycin CP478_RS14890 25bd410c95c0ec0e76142b707074eaf6 164 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 1 164 27.543 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 CP478_RS14890 25bd410c95c0ec0e76142b707074eaf6 164 Gene3D G3DSA:2.40.128.20 1 164 1.5E-51 T 28-03-2018 IPR012674 Calycin CP478_RS14890 25bd410c95c0ec0e76142b707074eaf6 164 Pfam PF08768 Domain of unknown function (DUF1794) 9 162 3.8E-43 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 Gene3D G3DSA:3.40.50.720 2 188 6.1E-52 T 28-03-2018 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 SUPERFAMILY SSF51735 5 187 7.77E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 PIRSF PIRSF000105 2 286 9.7E-83 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 SUPERFAMILY SSF48179 190 286 1.62E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 1.2E-59 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 Gene3D G3DSA:1.10.1040.10 189 286 7.6E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS02495 6ca72f7ac6688b1184f6046b0e1757d9 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 3.1E-33 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 Pfam PF01580 FtsK/SpoIIIE family 501 702 3.9E-65 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 SUPERFAMILY SSF46785 804 869 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 173 291 2.1E-5 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 SMART SM00843 803 868 5.2E-32 T 28-03-2018 IPR018541 FtsK gamma domain CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 Gene3D G3DSA:3.40.50.300 491 741 1.5E-46 T 28-03-2018 CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 Pfam PF09397 Ftsk gamma domain 808 865 1.4E-23 T 28-03-2018 IPR018541 FtsK gamma domain CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 SUPERFAMILY SSF52540 476 772 2.34E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15060 b1ce6cdb3280be72b96a2eff642b08e5 883 Gene3D G3DSA:1.10.10.10 805 859 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08635 d62f2040be92aef7e54760598c3c3717 170 Gene3D G3DSA:3.20.16.10 8 162 2.0E-27 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CP478_RS08635 d62f2040be92aef7e54760598c3c3717 170 Pfam PF04586 Caudovirus prohead serine protease 9 154 3.0E-19 T 28-03-2018 IPR006433 Prohead protease CP478_RS08635 d62f2040be92aef7e54760598c3c3717 170 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 14 151 1.8E-44 T 28-03-2018 IPR006433 Prohead protease CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 Pfam PF01965 DJ-1/PfpI family 11 62 2.4E-7 T 28-03-2018 IPR002818 DJ-1/PfpI CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 Gene3D G3DSA:1.10.10.60 213 259 7.9E-11 T 28-03-2018 CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 Gene3D G3DSA:1.10.10.60 149 212 5.8E-11 T 28-03-2018 CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 SUPERFAMILY SSF46689 208 258 3.27E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 Gene3D G3DSA:3.40.50.880 3 118 2.9E-14 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 Pfam PF12833 Helix-turn-helix domain 178 256 2.5E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 SUPERFAMILY SSF52317 8 62 1.76E-11 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 SUPERFAMILY SSF46689 172 205 4.3E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS10505 3fe1d0f42081df3f8ce07e76b6792a62 259 SMART SM00342 172 255 2.3E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS08795 0751aaa71b548fad0bb8ad7c76cb3a3e 154 Pfam PF00578 AhpC/TSA family 4 127 3.4E-30 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS08795 0751aaa71b548fad0bb8ad7c76cb3a3e 154 SUPERFAMILY SSF52833 2 151 8.28E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS08795 0751aaa71b548fad0bb8ad7c76cb3a3e 154 PIRSF PIRSF000239 1 154 1.4E-20 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS08795 0751aaa71b548fad0bb8ad7c76cb3a3e 154 Gene3D G3DSA:3.40.30.10 1 151 3.0E-35 T 28-03-2018 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 Pfam PF02384 N-6 DNA Methylase 177 503 3.3E-125 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 Pfam PF12161 HsdM N-terminal domain 18 164 9.2E-26 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 217 9.9E-19 T 28-03-2018 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 9.9E-19 T 28-03-2018 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 299 311 9.9E-19 T 28-03-2018 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 9.9E-19 T 28-03-2018 CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 SUPERFAMILY SSF53335 16 55 9.01E-135 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 SUPERFAMILY SSF53335 89 539 9.01E-135 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15100 342799d38004c9bbf3054c0013417ea3 540 Gene3D G3DSA:3.40.50.150 199 496 2.8E-58 T 28-03-2018 CP478_RS04900 120bef713da387847dcf383e1b9c185a 87 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 9 85 7.0E-27 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c CP478_RS04900 120bef713da387847dcf383e1b9c185a 87 Pfam PF10944 Protein of unknown function (DUF2630) 8 86 1.1E-32 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF53474 1141 1394 1.04E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF53474 1050 1088 1.04E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SMART SM00823 Phosphopantetheine attachment site 1020 1092 5.2E-27 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SMART SM00823 Phosphopantetheine attachment site 12 83 0.35 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.30.70.250 767 807 9.4E-19 T 28-03-2018 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 354 469 3.3E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF53901 500 521 1.5E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF53901 106 467 1.5E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.40.366.10 808 927 3.2E-30 T 28-03-2018 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 107 346 3.3E-84 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 474 597 7.0E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF55048 757 818 1.05E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SMART SM00825 Beta-ketoacyl synthase 109 525 1.3E-185 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 634 925 2.6E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF00698 Acyl transferase domain 633 942 9.9E-62 T 28-03-2018 IPR014043 Acyl transferase CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:1.10.1200.10 2 87 1.2E-8 T 28-03-2018 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF47336 7 121 4.58E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF00975 Thioesterase domain 1180 1392 3.4E-13 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 259 275 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.40.50.1820 1109 1399 8.0E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.40.47.10 100 358 3.4E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1047 1062 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.40.47.10 361 523 9.7E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF52151 631 752 3.92E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF52151 811 922 3.92E-76 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:3.40.366.10 630 766 6.6E-46 T 28-03-2018 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SMART SM00824 Thioesterase 1167 1393 8.4E-83 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF00550 Phosphopantetheine attachment site 14 77 9.0E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Pfam PF00550 Phosphopantetheine attachment site 1022 1088 2.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 SUPERFAMILY SSF47336 1014 1103 2.09E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS02160 be152e952b6a6293f18cbbecf6546a18 1402 Gene3D G3DSA:1.10.1200.10 1002 1101 2.4E-17 T 28-03-2018 CP478_RS01850 2178d308cd3cefed9383e19fb86f7ad1 487 PIRSF PIRSF006060 8 478 8.6E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS01850 2178d308cd3cefed9383e19fb86f7ad1 487 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CP478_RS01850 2178d308cd3cefed9383e19fb86f7ad1 487 Pfam PF00324 Amino acid permease 27 435 7.2E-100 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 TIGRFAM TIGR01083 nth: endonuclease III 16 205 1.7E-80 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Gene3D G3DSA:1.10.1670.10 129 228 1.5E-28 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Hamap MF_00942 Endonuclease III [nth]. 7 220 36.683 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 SMART SM00478 49 196 1.5E-60 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 SUPERFAMILY SSF48150 18 216 6.12E-64 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 198 214 1.6E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Pfam PF00633 Helix-hairpin-helix motif 110 137 2.7E-9 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 179 3.0E-22 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 SMART SM00525 197 217 6.4E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 PIRSF PIRSF001435 13 222 4.9E-44 T 28-03-2018 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 198 214 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 Gene3D G3DSA:1.10.340.30 36 128 5.1E-24 T 28-03-2018 CP478_RS20060 3ba70bf48df903d63506ec9390236e67 245 ProSitePatterns PS01155 Endonuclease III family signature. 113 142 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CP478_RS16345 9852da19aa59b418e20a5f3eb5156160 286 SUPERFAMILY SSF53335 195 222 5.94E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16345 9852da19aa59b418e20a5f3eb5156160 286 SUPERFAMILY SSF53335 41 166 5.94E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16345 9852da19aa59b418e20a5f3eb5156160 286 Gene3D G3DSA:3.40.50.150 16 284 1.3E-12 T 28-03-2018 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.2E-52 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 PIRSF PIRSF000429 1 391 7.1E-118 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 Pfam PF02803 Thiolase, C-terminal domain 269 390 3.9E-39 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 Gene3D G3DSA:3.40.47.10 263 391 3.1E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 SUPERFAMILY SSF53901 5 268 3.33E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 4.2E-110 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 Gene3D G3DSA:3.40.47.10 1 145 3.2E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 Gene3D G3DSA:3.40.47.10 150 262 3.5E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19380 b0699ec4a9dcaa57b8d3e0cd56a622a6 391 SUPERFAMILY SSF53901 269 390 3.37E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1015 1030 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:3.30.559.10 1063 1273 1.2E-36 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF52777 1261 1504 6.23E-55 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 ProSitePatterns PS00455 Putative AMP-binding domain signature. 622 633 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 515 901 1.2E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF00550 Phosphopantetheine attachment site 1630 1692 1.2E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF00550 Phosphopantetheine attachment site 993 1056 3.0E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:3.40.50.980 601 782 7.9E-46 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:2.30.38.10 783 869 1.1E-21 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SMART SM01294 1629 1692 0.0046 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:3.30.559.10 31 227 4.7E-32 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF56801 1531 1604 1.16E-9 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SMART SM00823 Phosphopantetheine attachment site 1628 1696 0.0049 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SMART SM00823 Phosphopantetheine attachment site 991 1060 6.0E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:2.30.38.10 1527 1604 1.2E-9 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:3.40.50.980 486 600 1.1E-34 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF00501 AMP-binding enzyme 496 877 3.3E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:3.30.300.30 872 996 7.2E-35 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF52777 218 458 1.01E-43 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF47336 1623 1692 3.27E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF00668 Condensation domain 43 474 9.2E-56 T 28-03-2018 IPR001242 Condensation domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF00668 Condensation domain 1077 1520 4.0E-72 T 28-03-2018 IPR001242 Condensation domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:1.10.1200.10 1622 1710 3.7E-20 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Gene3D G3DSA:1.10.1200.10 997 1062 8.8E-24 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 Pfam PF13193 AMP-binding enzyme C-terminal domain 887 966 2.5E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF52777 1079 1249 4.78E-43 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF47336 984 1056 2.75E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF52777 43 226 1.11E-34 T 28-03-2018 CP478_RS12975 fb55c2ee15b14dec707ac76aaa2783b6 1731 SUPERFAMILY SSF56801 463 1003 6.54E-150 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Pfam PF00702 haloacid dehalogenase-like hydrolase 1047 1352 4.1E-25 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF81665 952 1045 4.97E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF81665 768 829 4.97E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF81665 1388 1595 4.97E-51 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF81653 854 951 2.75E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1237 1248 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 892 906 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1259 1269 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1051 1065 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1338 1357 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1362 1374 1.6E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1310 1326 1.8E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1370 1395 1.8E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1338 1354 1.8E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1189 1207 1.8E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Pfam PF00122 E1-E2 ATPase 851 1029 4.2E-37 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 1053 1059 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF56784 1049 1069 8.25E-46 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 SUPERFAMILY SSF56784 1186 1444 8.25E-46 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Gene3D G3DSA:2.70.150.10 779 954 2.0E-26 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Gene3D G3DSA:1.20.1110.10 1364 1606 3.6E-33 T 28-03-2018 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Gene3D G3DSA:3.40.1110.10 1013 1229 2.7E-37 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 854 1080 5.3E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1304 1419 7.3E-28 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Pfam PF00689 Cation transporting ATPase, C-terminus 1426 1597 4.1E-16 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CP478_RS00590 053fd1b9998c22d7701650dca6e0bb6d 1625 Gene3D G3DSA:3.40.50.1000 1230 1363 1.5E-21 T 28-03-2018 IPR023214 HAD-like domain CP478_RS11705 3cf4c6a6fd30cc6d3a4fe0958a17575c 314 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 94 314 18.687 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 CP478_RS11705 3cf4c6a6fd30cc6d3a4fe0958a17575c 314 Pfam PF03799 Cell division protein FtsQ 205 298 8.5E-8 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CP478_RS11705 3cf4c6a6fd30cc6d3a4fe0958a17575c 314 Pfam PF08478 POTRA domain, FtsQ-type 125 192 6.7E-15 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CP478_RS11705 3cf4c6a6fd30cc6d3a4fe0958a17575c 314 Gene3D G3DSA:1.10.8.50 127 206 1.6E-4 T 28-03-2018 CP478_RS13265 d4f8abf46e5a0337349489899b940f97 195 Gene3D G3DSA:3.30.1020.10 163 194 1.9E-5 T 28-03-2018 CP478_RS13265 d4f8abf46e5a0337349489899b940f97 195 PIRSF PIRSF000239 1 195 3.2E-48 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS13265 d4f8abf46e5a0337349489899b940f97 195 Pfam PF00578 AhpC/TSA family 6 146 4.7E-32 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS13265 d4f8abf46e5a0337349489899b940f97 195 SUPERFAMILY SSF52833 4 188 5.24E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS13265 d4f8abf46e5a0337349489899b940f97 195 Gene3D G3DSA:3.40.30.10 1 162 2.8E-37 T 28-03-2018 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 310 2.8E-59 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Pfam PF13361 UvrD-like helicase C-terminal domain 595 687 9.0E-7 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Gene3D G3DSA:3.40.50.300 321 459 3.0E-8 T 28-03-2018 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Pfam PF12705 PD-(D/E)XK nuclease superfamily 831 1052 2.5E-5 T 28-03-2018 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Gene3D G3DSA:3.90.320.10 764 1094 7.4E-70 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1088 16.701 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 199 1087 9.7E-292 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52980 775 1088 3.7E-60 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Gene3D G3DSA:3.40.50.300 11 319 7.1E-43 T 28-03-2018 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 Gene3D G3DSA:3.40.50.300 489 728 1.8E-22 T 28-03-2018 CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52540 15 70 2.79E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52540 204 346 2.79E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52540 110 167 2.79E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52540 376 640 2.79E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03385 a332cd445927732d70d3abbf0f7c28bc 1094 SUPERFAMILY SSF52540 668 694 2.79E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 PRINTS PR01217 Proline rich extensin signature 466 478 1.2E-9 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 PRINTS PR01217 Proline rich extensin signature 501 513 1.2E-9 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 PRINTS PR01217 Proline rich extensin signature 543 559 1.2E-9 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 PRINTS PR01217 Proline rich extensin signature 513 534 1.2E-9 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 PRINTS PR01217 Proline rich extensin signature 480 496 1.2E-9 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 Pfam PF00012 Hsp70 protein 150 363 1.2E-17 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 SUPERFAMILY SSF53067 167 349 1.49E-30 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 Gene3D G3DSA:3.30.420.40 177 327 3.4E-19 T 28-03-2018 CP478_RS12315 97fb8f56bdca2d1bdbff5e89ee2f5470 592 Gene3D G3DSA:3.30.420.40 8 176 2.3E-7 T 28-03-2018 CP478_RS10575 863bef97e6e89e8d0c4f326d54df9fba 196 Gene3D G3DSA:3.10.450.50 22 188 1.6E-11 T 28-03-2018 CP478_RS10575 863bef97e6e89e8d0c4f326d54df9fba 196 SUPERFAMILY SSF103642 167 186 8.34E-7 T 28-03-2018 CP478_RS10575 863bef97e6e89e8d0c4f326d54df9fba 196 Pfam PF02810 SEC-C motif 168 185 1.1E-9 T 28-03-2018 IPR004027 SEC-C motif CP478_RS07835 c2f1242b457b3a0baa17f6e2f7272093 271 SUPERFAMILY SSF141523 167 269 1.57E-25 T 28-03-2018 CP478_RS07835 c2f1242b457b3a0baa17f6e2f7272093 271 Gene3D G3DSA:2.40.440.10 118 271 2.2E-23 T 28-03-2018 CP478_RS07835 c2f1242b457b3a0baa17f6e2f7272093 271 Pfam PF03734 L,D-transpeptidase catalytic domain 167 269 5.2E-15 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Gene3D G3DSA:1.10.1200.70 342 427 1.7E-21 T 28-03-2018 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 328 426 4.4E-21 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 427 9.8E-158 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 SUPERFAMILY SSF69742 3 158 1.57E-41 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 314 6.0E-30 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 156 2.4E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 424 26.485 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 SUPERFAMILY SSF51735 163 314 2.41E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 SUPERFAMILY SSF69075 325 427 1.2E-15 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 Gene3D G3DSA:3.40.50.720 161 322 9.9E-28 T 28-03-2018 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS02725 f201383d4d5366b13fd8dca2de26c1a3 468 PIRSF PIRSF000445 1 437 3.0E-138 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CP478_RS09585 4adefa930657b6a04e278f8ba2ea4934 914 SUPERFAMILY SSF140459 8 84 7.85E-24 T 28-03-2018 CP478_RS09585 4adefa930657b6a04e278f8ba2ea4934 914 Pfam PF00934 PE family 1 93 2.9E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 Gene3D G3DSA:3.40.50.880 245 467 2.6E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 Gene3D G3DSA:3.40.50.300 2 244 2.9E-53 T 28-03-2018 CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 233 3.9E-23 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 473 9.8E-128 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 SUPERFAMILY SSF52317 255 439 4.73E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 SUPERFAMILY SSF52540 1 240 5.65E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 481 176.036 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CP478_RS01375 938accb94dc6f0f45903f4473130b050 494 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 429 8.4E-44 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CP478_RS03435 2e0972b8fef4a3d48ccfc683287c7cdb 142 Gene3D G3DSA:3.10.129.10 2 139 5.1E-33 T 28-03-2018 CP478_RS03435 2e0972b8fef4a3d48ccfc683287c7cdb 142 SUPERFAMILY SSF54637 6 132 3.92E-25 T 28-03-2018 IPR029069 HotDog domain CP478_RS03435 2e0972b8fef4a3d48ccfc683287c7cdb 142 Pfam PF01575 MaoC like domain 15 125 2.2E-29 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 Gene3D G3DSA:2.60.40.10 1 76 2.0E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 545 1.5E-233 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 Pfam PF11941 Domain of unknown function (DUF3459) 491 573 3.3E-15 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 SMART SM00642 102 447 7.5E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 SUPERFAMILY SSF51445 86 505 4.7E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 Gene3D G3DSA:3.20.20.80 92 429 5.8E-57 T 28-03-2018 CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 Pfam PF00128 Alpha amylase, catalytic domain 112 210 6.2E-13 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 Gene3D G3DSA:1.10.10.760 432 470 3.8E-15 T 28-03-2018 CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 SUPERFAMILY SSF81296 4 75 2.0E-13 T 28-03-2018 IPR014756 Immunoglobulin E-set CP478_RS08555 455d8a1198d8aaebacffb8431bc717c1 580 PIRSF PIRSF006337 1 577 1.4E-230 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 36 499 2.6E-142 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Pfam PF01225 Mur ligase family, catalytic domain 34 84 1.8E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Pfam PF02875 Mur ligase family, glutamate ligase domain 343 429 2.5E-27 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Gene3D G3DSA:3.40.1190.10 116 337 5.9E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 500 30.018 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Gene3D G3DSA:3.90.190.20 341 507 1.6E-46 T 28-03-2018 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 SUPERFAMILY SSF53623 129 337 2.09E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 SUPERFAMILY SSF63418 4 87 5.62E-16 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Pfam PF08245 Mur ligase middle domain 134 321 4.3E-39 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 SUPERFAMILY SSF53244 343 499 2.52E-29 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11735 7180778c4210d5ce9703e009f4c26368 510 Gene3D G3DSA:3.40.1390.10 2 115 3.5E-25 T 28-03-2018 CP478_RS16080 369a086d22942291cb3cadb674ad2ba5 413 Gene3D G3DSA:3.30.420.10 108 313 2.2E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS16080 369a086d22942291cb3cadb674ad2ba5 413 SUPERFAMILY SSF53098 141 282 5.88E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS16080 369a086d22942291cb3cadb674ad2ba5 413 Gene3D G3DSA:1.10.10.60 1 44 7.0E-9 T 28-03-2018 CP478_RS16080 369a086d22942291cb3cadb674ad2ba5 413 Pfam PF00665 Integrase core domain 116 244 2.0E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 ProSitePatterns PS01047 Heavy-metal-associated domain. 21 49 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF81653 249 344 1.7E-18 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF81665 200 247 1.31E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF81665 693 718 1.31E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF81665 345 438 1.31E-10 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF56784 536 744 7.81E-53 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF56784 442 462 7.81E-53 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Gene3D G3DSA:1.20.1110.10 201 462 3.4E-42 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Gene3D G3DSA:3.30.70.100 11 83 3.3E-17 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 446 452 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 SUPERFAMILY SSF55008 13 80 5.24E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 167 746 6.5E-164 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Pfam PF00702 haloacid dehalogenase-like hydrolase 440 658 2.0E-44 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Pfam PF00122 E1-E2 ATPase 249 422 8.2E-44 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00940 Cation-transporting P-type ATPase A signature 247 266 7.7E-41 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00940 Cation-transporting P-type ATPase A signature 194 211 7.7E-41 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00940 Cation-transporting P-type ATPase A signature 112 129 7.7E-41 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00940 Cation-transporting P-type ATPase A signature 94 112 7.7E-41 T 28-03-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Gene3D G3DSA:3.40.50.1000 568 716 9.1E-38 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00570 1567c6712671f6d723f345b756e456de 752 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 747 1.4E-142 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Pfam PF00403 Heavy-metal-associated domain 19 76 8.6E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 552 724 1.3E-37 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 217 480 8.2E-36 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 Gene3D G3DSA:3.40.1110.10 463 567 1.6E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 4.9E-24 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 679 4.9E-24 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 601 4.9E-24 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 458 4.9E-24 T 28-03-2018 CP478_RS00570 1567c6712671f6d723f345b756e456de 752 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 4.9E-24 T 28-03-2018 CP478_RS05485 d230fe9a87d0c302f984e3176bf605e2 503 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 100 280 2.2E-12 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CP478_RS05485 d230fe9a87d0c302f984e3176bf605e2 503 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 311 502 3.9E-17 T 28-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CP478_RS11845 b1ed79005818016e1e094ca1cb545572 462 Gene3D G3DSA:3.20.20.70 206 407 1.1E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS11845 b1ed79005818016e1e094ca1cb545572 462 Pfam PF01474 Class-II DAHP synthetase family 31 457 1.7E-186 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CP478_RS11845 b1ed79005818016e1e094ca1cb545572 462 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 25 462 8.6E-226 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CP478_RS11845 b1ed79005818016e1e094ca1cb545572 462 SUPERFAMILY SSF51569 4 461 7.18E-191 T 28-03-2018 CP478_RS01415 1efedefa82a798be4f6b4130e32978c6 181 Pfam PF13527 Acetyltransferase (GNAT) domain 18 131 6.1E-11 T 28-03-2018 CP478_RS01415 1efedefa82a798be4f6b4130e32978c6 181 Gene3D G3DSA:3.40.630.30 1 181 3.3E-29 T 28-03-2018 CP478_RS01415 1efedefa82a798be4f6b4130e32978c6 181 SUPERFAMILY SSF55729 13 181 2.42E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 9.9E-35 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 9.9E-35 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 9.9E-35 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 9.9E-35 T 28-03-2018 IPR000362 Fumarate lyase family CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Pfam PF00206 Lyase 18 342 1.6E-101 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Gene3D G3DSA:1.20.200.10 137 415 2.5E-80 T 28-03-2018 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Hamap MF_00743 Fumarate hydratase class II [fumC]. 10 466 79.755 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Gene3D G3DSA:1.10.40.30 416 469 4.4E-22 T 28-03-2018 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Pfam PF10415 Fumarase C C-terminus 408 464 5.0E-18 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 SUPERFAMILY SSF48557 10 465 2.67E-139 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CP478_RS06030 d3e2ba71ee2b7785851db35c6941fce4 474 Gene3D G3DSA:1.10.275.10 8 136 2.1E-51 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SMART SM00382 599 757 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SMART SM00382 198 343 2.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Gene3D G3DSA:3.40.50.300 554 755 1.9E-45 T 28-03-2018 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 840 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Gene3D G3DSA:1.10.1780.10 5 151 7.8E-34 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Gene3D G3DSA:1.10.8.60 756 847 3.8E-25 T 28-03-2018 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SUPERFAMILY SSF52540 548 838 5.63E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 6.9E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 9.4E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SUPERFAMILY SSF52540 157 547 2.91E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 756 835 2.5E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SUPERFAMILY SSF81923 7 155 1.77E-35 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 749 4.9E-49 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 3.8E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 3.8E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 3.8E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 3.8E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Gene3D G3DSA:3.40.50.300 157 343 3.9E-25 T 28-03-2018 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Gene3D G3DSA:1.10.8.60 344 549 3.5E-45 T 28-03-2018 CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 SMART SM01086 756 847 8.9E-36 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS02045 546070d9e1b445fc0e147bbb25afbe3b 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 334 1.6E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 SUPERFAMILY SSF54593 1 123 7.89E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 Gene3D G3DSA:3.10.180.10 133 299 6.0E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 Gene3D G3DSA:3.10.180.10 1 132 2.9E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 SUPERFAMILY SSF54593 135 292 8.59E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 267 9.8E-21 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS19505 d7e56802897df0fd4b597be72a3f4f2e 300 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 SUPERFAMILY SSF51569 4 340 1.54E-99 T 28-03-2018 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 PIRSF PIRSF001359 6 341 1.6E-64 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 4.8E-82 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 Gene3D G3DSA:3.20.20.70 1 344 2.2E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 1.8E-75 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CP478_RS01940 8b6e55befd28522000d1ae5c72b2b5bd 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 340 1.0E-159 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CP478_RS17075 291d6c641827ac2696d33712585aaebb 200 Gene3D G3DSA:3.40.50.150 10 197 2.8E-20 T 28-03-2018 CP478_RS17075 291d6c641827ac2696d33712585aaebb 200 Pfam PF13649 Methyltransferase domain 51 140 8.0E-10 T 28-03-2018 CP478_RS17075 291d6c641827ac2696d33712585aaebb 200 SUPERFAMILY SSF53335 18 188 2.6E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.90.180.10 1405 1556 1.8E-36 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF47336 2022 2107 1.15E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.50.720 1557 1710 2.0E-26 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 176 192 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 16 263 2.3E-89 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:1.10.1200.10 2014 2104 5.0E-12 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF14765 Polyketide synthase dehydratase 905 1186 8.7E-48 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.30.70.250 682 728 2.9E-9 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF08659 KR domain 1765 1942 2.4E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF50129 1424 1560 9.43E-34 T 28-03-2018 IPR011032 GroES-like CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF51735 1763 1990 4.93E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF00107 Zinc-binding dehydrogenase 1570 1660 7.1E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.47.10 278 437 1.5E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF51735 1196 1404 8.46E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.10.129.10 926 1025 1.8E-9 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF55048 669 734 5.1E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 271 384 3.6E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF00698 Acyl transferase domain 546 861 1.7E-102 T 28-03-2018 IPR014043 Acyl transferase CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00826 905 1070 5.7E-34 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF53901 12 383 6.98E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.366.10 729 846 4.9E-23 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 548 843 4.5E-86 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.366.10 545 681 6.0E-35 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.47.10 7 275 1.3E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1765 1944 7.6E-41 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1446 1512 1.5E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00823 Phosphopantetheine attachment site 2032 2098 1.7E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00825 Beta-ketoacyl synthase 17 439 1.0E-181 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Gene3D G3DSA:3.40.50.720 1748 1984 1.9E-41 T 28-03-2018 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SMART SM00829 1429 1741 4.4E-157 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 395 509 1.6E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF51735 1530 1692 2.21E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 Pfam PF00550 Phosphopantetheine attachment site 2029 2093 7.8E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF52151 546 670 1.46E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS08375 b5f638d0ff8646771ebdbd17309ca4d0 2108 SUPERFAMILY SSF52151 735 833 1.46E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS05420 7b1d37e600a0d04731dd0a42fcb5121d 306 Gene3D G3DSA:3.90.550.10 5 303 3.3E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS05420 7b1d37e600a0d04731dd0a42fcb5121d 306 Pfam PF00483 Nucleotidyl transferase 12 280 3.6E-26 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CP478_RS05420 7b1d37e600a0d04731dd0a42fcb5121d 306 SUPERFAMILY SSF53448 10 293 4.51E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 122 135 3.6E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 339 355 3.6E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 PRINTS PR00723 Subtilisin serine protease family (S8) signature 86 105 3.6E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 75 457 2.2E-122 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 SUPERFAMILY SSF52743 270 398 3.14E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 SUPERFAMILY SSF52743 72 241 3.14E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 Gene3D G3DSA:3.40.50.200 71 406 1.4E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 Pfam PF00082 Subtilase family 86 389 4.7E-36 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS01570 8d516e66ada5b47a5625633ed525bfda 461 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 126 136 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 SMART SM00100 20 140 5.6E-23 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 Pfam PF00027 Cyclic nucleotide-binding domain 40 119 1.1E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 87 104 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 Pfam PF13302 Acetyltransferase (GNAT) domain 156 289 4.1E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 SUPERFAMILY SSF51206 15 141 1.13E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 Gene3D G3DSA:2.60.120.10 11 145 1.1E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 SUPERFAMILY SSF55729 153 294 7.85E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS05465 4723d5fe69d67856e7e937764731274e 333 Gene3D G3DSA:3.40.630.30 146 331 2.8E-21 T 28-03-2018 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 325 2.6E-138 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 Gene3D G3DSA:3.40.50.10680 124 331 9.4E-40 T 28-03-2018 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 Pfam PF01933 Uncharacterised protein family UPF0052 3 294 1.7E-63 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 SUPERFAMILY SSF142338 3 327 4.97E-80 T 28-03-2018 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 Gene3D G3DSA:1.10.8.240 50 123 1.2E-38 T 28-03-2018 CP478_RS17880 da6b62c8da5938856e867f7a77258211 331 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 331 135.802 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 7 218 1.2E-70 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 SUPERFAMILY SSF88697 236 292 4.72E-14 T 28-03-2018 IPR015947 PUA-like domain CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Gene3D G3DSA:2.30.130.10 228 290 1.6E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Gene3D G3DSA:3.30.2350.10 5 226 3.6E-82 T 28-03-2018 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 27 179 6.2E-52 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 236 291 6.1E-22 T 28-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 221 1.5E-12 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 5 296 17.395 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS15290 e5022d66fc391ae31f70aa951fd58983 298 SUPERFAMILY SSF55120 7 222 3.04E-73 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Pfam PF12826 Helix-hairpin-helix motif 527 590 2.2E-22 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:1.10.150.20 523 588 1.1E-28 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SMART SM00292 609 686 1.1E-14 T 28-03-2018 IPR001357 BRCT domain CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:2.40.50.140 332 399 2.5E-29 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SUPERFAMILY SSF47781 413 600 9.27E-49 T 28-03-2018 IPR010994 RuvA domain 2-like CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 678 4.0E-252 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 PIRSF PIRSF001604 5 687 4.1E-232 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:1.10.287.610 3 76 8.5E-29 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 331 408 2.4E-31 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SMART SM00532 12 459 6.9E-278 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SUPERFAMILY SSF56091 12 326 1.22E-111 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:1.10.150.20 443 522 1.1E-17 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:3.30.1490.70 91 169 1.4E-19 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:3.30.1490.70 218 331 8.7E-28 T 28-03-2018 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Hamap MF_01588 DNA ligase [ligA]. 15 683 51.067 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SUPERFAMILY SSF50249 327 410 1.54E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 444 8.0E-8 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 SUPERFAMILY SSF52113 611 684 6.54E-18 T 28-03-2018 IPR001357 BRCT domain CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 611 682 1.7E-13 T 28-03-2018 IPR001357 BRCT domain CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 13 328 7.8E-126 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CP478_RS16485 4a47cb03d4c8053c5eb93d797a27ab33 691 Gene3D G3DSA:3.40.50.10190 589 686 5.4E-21 T 28-03-2018 IPR001357 BRCT domain CP478_RS13805 8611646cf1e763fe52d7065ff74cf74b 75 Pfam PF12277 Protein of unknown function (DUF3618) 3 48 3.6E-18 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 SUPERFAMILY SSF55347 158 320 1.2E-44 T 28-03-2018 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 169 323 7.2E-26 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 10 346 38.283 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 11 140 5.5E-20 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 153 169 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 Gene3D G3DSA:3.30.360.10 165 320 2.0E-52 T 28-03-2018 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 11 352 3.0E-114 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 SMART SM00859 11 148 1.2E-38 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 Gene3D G3DSA:3.40.50.720 1 164 1.8E-43 T 28-03-2018 CP478_RS09040 c9c2d4840f7cb61ed6b071229c4787fe 352 SUPERFAMILY SSF51735 9 183 2.96E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01690 316a219408fc15f4567758eda5f07b40 204 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 108 150 2.0E-6 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CP478_RS01690 316a219408fc15f4567758eda5f07b40 204 Pfam PF02426 Muconolactone delta-isomerase 108 199 2.1E-26 T 28-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CP478_RS01690 316a219408fc15f4567758eda5f07b40 204 Pfam PF02426 Muconolactone delta-isomerase 1 93 2.2E-31 T 28-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CP478_RS01690 316a219408fc15f4567758eda5f07b40 204 SUPERFAMILY SSF54909 108 202 3.75E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS01690 316a219408fc15f4567758eda5f07b40 204 SUPERFAMILY SSF54909 1 96 9.38E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SMART SM00482 660 867 1.2E-118 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Pfam PF00476 DNA polymerase family A 527 900 4.1E-144 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 ProSitePatterns PS00447 DNA polymerase family A signature. 729 748 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SMART SM00475 13 275 9.9E-142 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:3.40.50.1010 15 197 1.2E-68 T 28-03-2018 IPR029060 PIN domain-like CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SUPERFAMILY SSF56672 501 901 4.45E-141 T 28-03-2018 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SUPERFAMILY SSF53098 323 493 1.02E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SUPERFAMILY SSF47807 185 298 5.68E-30 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SMART SM00474 317 493 7.0E-28 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:1.20.1060.10 518 630 8.2E-24 T 28-03-2018 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SMART SM00279 187 222 6.0E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 186 279 4.7E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 TIGRFAM TIGR00593 pola: DNA polymerase I 17 902 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:3.30.420.10 343 517 3.7E-23 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:1.10.150.20 198 276 7.3E-25 T 28-03-2018 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 17 184 8.2E-54 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 667 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 718 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 850 863 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 766 777 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 651 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 788 799 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 729 754 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 820 836 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 675 698 2.7E-76 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 SUPERFAMILY SSF88723 11 184 3.92E-54 T 28-03-2018 IPR029060 PIN domain-like CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:3.30.70.370 631 725 1.8E-17 T 28-03-2018 CP478_RS08910 17bccfc494e78114f77ffbcbfe25e8aa 904 Gene3D G3DSA:3.30.70.370 729 904 5.8E-46 T 28-03-2018 CP478_RS20735 959fd64179265172ecd75b69c8f4a6c9 375 Pfam PF00753 Metallo-beta-lactamase superfamily 81 126 1.4E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20735 959fd64179265172ecd75b69c8f4a6c9 375 Pfam PF12706 Beta-lactamase superfamily domain 232 342 1.6E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20735 959fd64179265172ecd75b69c8f4a6c9 375 Gene3D G3DSA:3.60.15.10 61 375 9.5E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20735 959fd64179265172ecd75b69c8f4a6c9 375 SUPERFAMILY SSF56281 226 374 8.54E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20735 959fd64179265172ecd75b69c8f4a6c9 375 SUPERFAMILY SSF56281 69 198 8.54E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 Gene3D G3DSA:1.10.357.10 89 223 1.3E-18 T 28-03-2018 CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 SUPERFAMILY SSF46689 31 115 7.48E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 90 3.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 SUPERFAMILY SSF48498 110 222 7.56E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS17585 54c7f7fb7803a3875670aa4165b70f08 228 Gene3D G3DSA:1.10.10.60 5 88 3.2E-20 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 Gene3D G3DSA:3.30.390.30 361 495 1.9E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 1.3E-18 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.3E-18 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 24 43 1.3E-18 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 295 1.3E-18 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 Gene3D G3DSA:3.50.50.60 19 182 4.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 377 483 1.3E-19 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 22 339 5.3E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 SUPERFAMILY SSF51905 18 351 2.88E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 SUPERFAMILY SSF55424 373 494 1.7E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 Gene3D G3DSA:3.40.50.720 183 356 3.0E-27 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 331 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 373 394 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 55 70 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 455 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 294 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 23 45 5.7E-50 T 28-03-2018 CP478_RS04315 a2fffda05de7fe4649dc2f4bb8ff8b30 499 PIRSF PIRSF000350 3 488 1.8E-62 T 28-03-2018 CP478_RS02980 9187fcbb80b6163aca79fd9dddb3ee4b 378 Pfam PF00534 Glycosyl transferases group 1 203 340 4.1E-22 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS02980 9187fcbb80b6163aca79fd9dddb3ee4b 378 Gene3D G3DSA:3.40.50.2000 4 195 2.7E-27 T 28-03-2018 CP478_RS02980 9187fcbb80b6163aca79fd9dddb3ee4b 378 Gene3D G3DSA:3.40.50.2000 196 353 1.9E-31 T 28-03-2018 CP478_RS02980 9187fcbb80b6163aca79fd9dddb3ee4b 378 Pfam PF13439 Glycosyltransferase Family 4 17 187 3.5E-27 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS02980 9187fcbb80b6163aca79fd9dddb3ee4b 378 SUPERFAMILY SSF53756 5 368 1.12E-69 T 28-03-2018 CP478_RS00895 631994740a367df20c5f08e7b057b58b 151 Gene3D G3DSA:3.10.129.10 14 147 9.0E-32 T 28-03-2018 CP478_RS00895 631994740a367df20c5f08e7b057b58b 151 Pfam PF03061 Thioesterase superfamily 31 111 9.1E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CP478_RS00895 631994740a367df20c5f08e7b057b58b 151 SUPERFAMILY SSF54637 12 145 1.41E-35 T 28-03-2018 IPR029069 HotDog domain CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 Gene3D G3DSA:3.40.50.720 16 269 3.2E-61 T 28-03-2018 CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 SUPERFAMILY SSF51735 15 269 1.43E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 268 3.1E-49 T 28-03-2018 CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 5.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 5.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 57 68 5.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 57 68 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09350 4f0165b50dc5cc85e62e155b926968bd 270 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 23 202 3.1E-5 T 28-03-2018 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 PIRSF PIRSF001348 1 606 3.1E-293 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Gene3D G3DSA:3.40.449.10 7 244 4.6E-113 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 606 52.126 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 245 605 7.6E-171 T 28-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 SUPERFAMILY SSF68923 12 244 3.4E-100 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 SUPERFAMILY SSF53795 245 605 3.2E-154 T 28-03-2018 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 240 5.8E-102 T 28-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 28-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Gene3D G3DSA:3.90.228.20 245 316 3.7E-20 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CP478_RS01145 04b2df5735042c65b402843180fd2db2 606 Gene3D G3DSA:3.90.228.20 327 606 1.3E-121 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 SUPERFAMILY SSF56327 157 325 1.25E-59 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 Gene3D G3DSA:3.40.50.720 7 156 2.9E-22 T 28-03-2018 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 322 7.2E-145 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 SUPERFAMILY SSF51735 4 155 1.61E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 150 2.3E-30 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 323 9.7E-33 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 Gene3D G3DSA:3.90.110.10 157 325 1.8E-53 T 28-03-2018 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 PIRSF PIRSF000102 2 326 1.1E-54 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CP478_RS06790 00e3d6e3fc91d71569215dcd3c391fca 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.212 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 793 805 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 777 793 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 763 777 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 SUPERFAMILY SSF46894 752 817 4.42E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 Pfam PF00196 Bacterial regulatory proteins, luxR family 762 816 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 Gene3D G3DSA:1.10.10.10 177 243 0.014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 ProSitePatterns PS00622 LuxR-type HTH domain signature. 777 804 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 Gene3D G3DSA:1.10.10.10 752 831 8.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 Gene3D G3DSA:1.25.40.10 280 728 2.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 SUPERFAMILY SSF52540 30 121 9.5E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 Gene3D G3DSA:3.40.50.300 6 176 2.0E-5 T 28-03-2018 CP478_RS01815 97c67eecfcbcb60efce901d49c433afa 832 SMART SM00421 760 817 1.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04795 e0d8dc81d48049cb0caad4ed33917c25 91 Pfam PF10745 Protein of unknown function (DUF2530) 10 84 5.2E-30 T 28-03-2018 IPR019681 Protein of unknown function DUF2530 CP478_RS12180 14ce7ce856505c841db76adb1640a2cf 153 PIRSF PIRSF000239 1 143 3.2E-24 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS12180 14ce7ce856505c841db76adb1640a2cf 153 Gene3D G3DSA:3.40.30.10 1 153 2.5E-33 T 28-03-2018 CP478_RS12180 14ce7ce856505c841db76adb1640a2cf 153 Pfam PF00578 AhpC/TSA family 4 129 1.1E-32 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS12180 14ce7ce856505c841db76adb1640a2cf 153 SUPERFAMILY SSF52833 1 151 1.27E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS03395 d4b00d6455c46ad1baefd5bea498762a 231 SUPERFAMILY SSF52096 3 225 1.56E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03395 d4b00d6455c46ad1baefd5bea498762a 231 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 207 8.9E-28 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS03395 d4b00d6455c46ad1baefd5bea498762a 231 Gene3D G3DSA:3.90.226.10 1 227 2.0E-40 T 28-03-2018 CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 SMART SM00862 158 233 1.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 233 2.4E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 Gene3D G3DSA:3.40.50.2300 5 132 1.0E-39 T 28-03-2018 CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 Gene3D G3DSA:1.10.10.10 133 236 7.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 SUPERFAMILY SSF52172 10 184 3.17E-41 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 SMART SM00448 11 122 3.9E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS04925 44c16b5ae07c761cc7ccaddb2e93fd00 236 Pfam PF00072 Response regulator receiver domain 13 123 4.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF51569 517 828 8.24E-75 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1126 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SMART SM00878 339 445 9.8E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1083 1100 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF00364 Biotin-requiring enzyme 1068 1125 4.6E-14 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.20.20.70 524 838 9.5E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:2.40.50.100 1057 1127 2.0E-15 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF02436 Conserved carboxylase domain 820 1009 2.7E-54 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF89000 825 993 8.24E-39 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF51230 1051 1126 9.68E-17 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF00682 HMGL-like 524 795 6.7E-26 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF51246 333 451 3.45E-38 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.40.50.20 1 121 4.8E-45 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 111 1.0E-38 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 PIRSF PIRSF001594 1 1127 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.30.1490.20 122 201 3.8E-16 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF52440 2 112 3.96E-40 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.30.470.20 204 447 2.5E-98 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 3.0E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.10.600.10 967 1044 1.1E-20 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Gene3D G3DSA:3.10.600.10 457 523 2.6E-8 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 SUPERFAMILY SSF56059 84 350 3.01E-63 T 28-03-2018 CP478_RS16220 fc0d67300295dfc1b77339af0b581928 1127 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 323 1.3E-66 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS05230 7bdb7630ce57d3528753672cb34cbcd3 459 SUPERFAMILY SSF52540 48 335 5.12E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05230 7bdb7630ce57d3528753672cb34cbcd3 459 Gene3D G3DSA:3.40.50.300 45 263 5.6E-14 T 28-03-2018 CP478_RS05230 7bdb7630ce57d3528753672cb34cbcd3 459 Pfam PF00158 Sigma-54 interaction domain 170 227 4.2E-5 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 Pfam PF00106 short chain dehydrogenase 12 196 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 SUPERFAMILY SSF51735 9 254 3.27E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 Gene3D G3DSA:3.40.50.720 4 264 1.0E-49 T 28-03-2018 CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS13715 86ca71687dbc4d133978cf4251e54f4c 268 PIRSF PIRSF000126 4 266 2.1E-71 T 28-03-2018 CP478_RS18675 18311a751ecfe7ca09cc797d0e689378 136 Pfam PF17252 Family of unknown function (DUF5319) 9 122 3.5E-50 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CP478_RS18675 18311a751ecfe7ca09cc797d0e689378 136 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 25 120 8.0E-51 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 Gene3D G3DSA:3.40.50.1240 4 237 1.0E-56 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 135 6.0E-28 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 PIRSF PIRSF000709 134 214 0.0066 T 28-03-2018 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 PIRSF PIRSF000709 3 118 1.5E-5 T 28-03-2018 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 SUPERFAMILY SSF53254 6 226 1.8E-68 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 SMART SM00855 6 190 1.8E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 248 7.6E-114 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CP478_RS02605 fccb6df5d2a68c9279142bac4bfd46b5 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 4 231 41.113 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 Gene3D G3DSA:2.60.120.460 1 127 1.2E-29 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 SUPERFAMILY SSF111038 3 125 1.26E-30 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 90 108 - T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 6 124 8.3E-22 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 Pfam PF01894 Uncharacterised protein family UPF0047 13 124 9.8E-25 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS14015 4c78c419316ae39264be921022dcb8bd 129 PIRSF PIRSF004681 1 129 2.6E-32 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CP478_RS06555 992c69d3b4952b0ba61f421d792adac1 391 SUPERFAMILY SSF140459 3 174 4.45E-61 T 28-03-2018 CP478_RS06555 992c69d3b4952b0ba61f421d792adac1 391 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 306 386 1.3E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS06555 992c69d3b4952b0ba61f421d792adac1 391 Pfam PF00823 PPE family 6 162 1.7E-59 T 28-03-2018 IPR000030 PPE family CP478_RS02650 3e6f95affcc5cca62fb2687dc100852f 328 Gene3D G3DSA:3.30.420.40 1 108 1.5E-26 T 28-03-2018 CP478_RS02650 3e6f95affcc5cca62fb2687dc100852f 328 SUPERFAMILY SSF53067 3 109 2.63E-21 T 28-03-2018 CP478_RS02650 3e6f95affcc5cca62fb2687dc100852f 328 Pfam PF02541 Ppx/GppA phosphatase family 1 291 7.5E-94 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CP478_RS02650 3e6f95affcc5cca62fb2687dc100852f 328 Gene3D G3DSA:3.30.420.150 111 294 1.0E-37 T 28-03-2018 CP478_RS02650 3e6f95affcc5cca62fb2687dc100852f 328 SUPERFAMILY SSF53067 113 289 4.4E-35 T 28-03-2018 CP478_RS18790 5aeb3e29e2672d834ce997572af1efcf 460 Gene3D G3DSA:3.40.640.10 66 323 8.1E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS18790 5aeb3e29e2672d834ce997572af1efcf 460 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 15 444 2.1E-210 T 28-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 CP478_RS18790 5aeb3e29e2672d834ce997572af1efcf 460 Gene3D G3DSA:3.90.1150.10 324 446 5.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS18790 5aeb3e29e2672d834ce997572af1efcf 460 SUPERFAMILY SSF53383 13 443 3.72E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS18790 5aeb3e29e2672d834ce997572af1efcf 460 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 41 380 1.0E-70 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 Gene3D G3DSA:3.40.50.300 129 179 3.6E-7 T 28-03-2018 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 PRINTS PR00094 Adenylate kinase signature 32 46 2.5E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 PRINTS PR00094 Adenylate kinase signature 4 17 2.5E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 PRINTS PR00094 Adenylate kinase signature 129 144 2.5E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 PRINTS PR00094 Adenylate kinase signature 81 97 2.5E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 PRINTS PR00094 Adenylate kinase signature 146 160 2.5E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 Pfam PF00406 Adenylate kinase 5 158 2.4E-53 T 28-03-2018 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 Hamap MF_00235 Adenylate kinase [adk]. 1 180 45.499 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 Gene3D G3DSA:3.40.50.300 1 128 1.3E-40 T 28-03-2018 CP478_RS03965 63bca189cc678a028583b69c6aff0086 181 SUPERFAMILY SSF52540 2 180 2.23E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09945 20e80fd70a8fbfa5ee00fb7c84c17558 162 SMART SM00240 76 126 8.7E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09945 20e80fd70a8fbfa5ee00fb7c84c17558 162 SUPERFAMILY SSF49879 44 148 1.53E-31 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS09945 20e80fd70a8fbfa5ee00fb7c84c17558 162 Pfam PF00498 FHA domain 78 140 3.0E-19 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09945 20e80fd70a8fbfa5ee00fb7c84c17558 162 Gene3D G3DSA:2.60.200.20 28 149 1.8E-29 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 SUPERFAMILY SSF56801 24 537 7.46E-93 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Gene3D G3DSA:3.30.300.30 435 540 1.0E-13 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Gene3D G3DSA:2.30.38.10 345 434 4.5E-14 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Gene3D G3DSA:3.40.50.980 162 329 6.2E-35 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Gene3D G3DSA:3.40.50.980 4 161 1.1E-23 T 28-03-2018 CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Pfam PF14535 AMP-binding enzyme C-terminal domain 444 536 3.0E-6 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal CP478_RS05545 8ff5b2ba3084270d51dc79a7042f68e3 544 Pfam PF00501 AMP-binding enzyme 27 442 1.0E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 3.1E-15 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 3.1E-15 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 3.1E-15 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 3.1E-15 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 SUPERFAMILY SSF55424 327 397 3.94E-17 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 309 8.3E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Gene3D G3DSA:3.50.50.60 1 29 0.12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Gene3D G3DSA:3.40.50.720 138 317 3.4E-37 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Pfam PF14759 Reductase C-terminal 330 398 2.4E-12 T 28-03-2018 IPR028202 Reductase, C-terminal CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Gene3D G3DSA:3.30.390.30 326 405 2.4E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 Gene3D G3DSA:3.50.50.60 30 137 8.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.3E-23 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.3E-23 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 3.3E-23 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.3E-23 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 3.3E-23 T 28-03-2018 CP478_RS03715 42885431aee838162a5c0f4bf8937b8f 406 SUPERFAMILY SSF51905 18 298 2.16E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 224 243 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 Pfam PF00266 Aminotransferase class-V 32 403 3.6E-140 T 28-03-2018 IPR000192 Aminotransferase class V domain CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 Gene3D G3DSA:3.40.640.10 41 289 2.1E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 SUPERFAMILY SSF53383 9 409 2.62E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 415 3.5E-173 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CP478_RS08025 9ef76467830a192f5bc018496663eb62 417 Gene3D G3DSA:3.90.1150.10 290 410 3.4E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS01370 c6d4386173c403838e3ea194998f28d3 174 Gene3D G3DSA:3.40.50.300 3 174 5.0E-48 T 28-03-2018 CP478_RS01370 c6d4386173c403838e3ea194998f28d3 174 PIRSF PIRSF006135 1 174 5.0E-53 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS01370 c6d4386173c403838e3ea194998f28d3 174 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 174 1.3E-49 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS01370 c6d4386173c403838e3ea194998f28d3 174 SUPERFAMILY SSF52540 3 173 2.18E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 SUPERFAMILY SSF53223 12 264 1.58E-91 T 28-03-2018 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 Pfam PF00390 Malic enzyme, N-terminal domain 74 254 1.1E-66 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PIRSF PIRSF000106 3 548 3.4E-196 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 SMART SM01274 73 255 9.3E-86 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 Gene3D G3DSA:3.40.50.10380 8 262 1.0E-91 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 261 277 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 236 254 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 292 308 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 400 416 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 79 103 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 177 199 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 PRINTS PR00072 Malic enzyme signature 141 170 5.3E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 Pfam PF03949 Malic enzyme, NAD binding domain 265 521 3.0E-97 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 SMART SM00919 265 522 1.1E-112 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 SUPERFAMILY SSF51735 266 547 1.99E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 ProSitePatterns PS00331 Malic enzymes signature. 261 277 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CP478_RS12720 4b8f4dad06570feb71ee72d2cb90ba42 548 Gene3D G3DSA:3.40.50.720 263 548 3.1E-97 T 28-03-2018 CP478_RS18395 2b131b86fdbb722d2c4c862d32cce473 85 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 6 85 2.9E-37 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CP478_RS18395 2b131b86fdbb722d2c4c862d32cce473 85 SUPERFAMILY SSF143011 4 84 6.02E-27 T 28-03-2018 IPR035095 Toxin RelE-like domain CP478_RS18395 2b131b86fdbb722d2c4c862d32cce473 85 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 6 85 1.1E-39 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CP478_RS18395 2b131b86fdbb722d2c4c862d32cce473 85 Gene3D G3DSA:3.30.2310.20 3 85 1.9E-23 T 28-03-2018 CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 7.3E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 150 8.6E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 151 24.406 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 150 1.2E-34 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 SUPERFAMILY SSF55653 61 150 1.1E-20 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 Gene3D G3DSA:3.10.430.100 63 150 2.5E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 Gene3D G3DSA:3.40.5.10 1 49 4.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 SUPERFAMILY SSF55658 1 57 3.31E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CP478_RS00305 f22200ae24a51caaf420bcc16786c1dc 152 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 Pfam PF00106 short chain dehydrogenase 7 198 2.4E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 SUPERFAMILY SSF51735 7 246 2.8E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.7E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 Gene3D G3DSA:3.40.50.720 1 250 1.4E-51 T 28-03-2018 CP478_RS06265 a0367f036c8eb1ee00c5fac3ef60aacb 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS20645 0b5bbc02c1e23715ee850631b59edf3e 398 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 394 1.9E-161 T 28-03-2018 IPR011340 Cysteine desulfurase-related CP478_RS20645 0b5bbc02c1e23715ee850631b59edf3e 398 Gene3D G3DSA:3.40.640.10 28 276 6.5E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS20645 0b5bbc02c1e23715ee850631b59edf3e 398 SUPERFAMILY SSF53383 3 396 1.09E-58 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS20645 0b5bbc02c1e23715ee850631b59edf3e 398 Gene3D G3DSA:3.90.1150.10 277 397 8.7E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS20645 0b5bbc02c1e23715ee850631b59edf3e 398 Pfam PF00266 Aminotransferase class-V 21 390 1.6E-36 T 28-03-2018 IPR000192 Aminotransferase class V domain CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 3.8E-14 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 3.8E-14 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 3.8E-14 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 Pfam PF00117 Glutamine amidotransferase class-I 5 189 1.7E-48 T 28-03-2018 IPR017926 Glutamine amidotransferase CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 103 111 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 50 59 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 168 181 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 123 135 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 78 89 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.1E-35 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 189 4.1E-60 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 Gene3D G3DSA:3.40.50.880 1 194 9.9E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 SUPERFAMILY SSF52317 1 192 2.96E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 8.6E-10 T 28-03-2018 CP478_RS00080 facab11f22a06566b9e9cc2b40ce4666 232 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 8.6E-10 T 28-03-2018 CP478_RS12300 ba7f9dd85a6886ac45adf82a167fe32a 211 Pfam PF00753 Metallo-beta-lactamase superfamily 24 190 1.3E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12300 ba7f9dd85a6886ac45adf82a167fe32a 211 Gene3D G3DSA:3.60.15.10 18 209 1.4E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12300 ba7f9dd85a6886ac45adf82a167fe32a 211 SMART SM00849 23 190 3.6E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12300 ba7f9dd85a6886ac45adf82a167fe32a 211 SUPERFAMILY SSF56281 9 203 1.83E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 Gene3D G3DSA:3.40.50.720 167 335 6.5E-19 T 28-03-2018 CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 SUPERFAMILY SSF50129 7 190 6.83E-38 T 28-03-2018 IPR011032 GroES-like CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 SUPERFAMILY SSF51735 155 328 2.19E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 147 3.1E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 Pfam PF00107 Zinc-binding dehydrogenase 193 325 2.2E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS08390 f552c75d12bf62d0a1b3dd7dfff83010 367 Gene3D G3DSA:3.90.180.10 2 166 3.5E-35 T 28-03-2018 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Gene3D G3DSA:3.40.50.300 6 54 8.5E-16 T 28-03-2018 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Gene3D G3DSA:3.30.300.20 187 300 1.0E-42 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 100 2.7E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 9 29 2.7E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 169 2.0E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Pfam PF07650 KH domain 210 289 5.9E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Hamap MF_00367 GTPase Era [era]. 4 300 35.084 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 283 1.4E-72 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 SUPERFAMILY SSF52540 9 214 6.64E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Gene3D G3DSA:3.40.50.300 55 177 2.6E-16 T 28-03-2018 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 SUPERFAMILY SSF54814 184 300 5.75E-36 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CP478_RS12895 63b36f5489939ce12becc29450971cf9 300 Pfam PF01926 50S ribosome-binding GTPase 9 125 1.2E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 Gene3D G3DSA:3.90.180.10 1 166 7.3E-33 T 28-03-2018 CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 Gene3D G3DSA:3.40.50.720 167 330 3.0E-23 T 28-03-2018 CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 SUPERFAMILY SSF50129 2 174 2.2E-29 T 28-03-2018 IPR011032 GroES-like CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 Pfam PF00107 Zinc-binding dehydrogenase 175 345 6.3E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 SUPERFAMILY SSF51735 142 222 1.87E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 SUPERFAMILY SSF51735 264 351 1.87E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20360 9e7442da2ac71ef12b8668b58ebcb629 397 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 102 1.0E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 Gene3D G3DSA:1.10.510.10 232 449 1.3E-22 T 28-03-2018 CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 Gene3D G3DSA:3.40.630.30 10 184 1.0E-20 T 28-03-2018 CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 Pfam PF01636 Phosphotransferase enzyme family 210 432 3.5E-33 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 SUPERFAMILY SSF55729 15 157 6.23E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 SUPERFAMILY SSF56112 191 438 4.52E-42 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS17695 487ae1f5dfbaa3f810b44a3a089e797c 474 Pfam PF13302 Acetyltransferase (GNAT) domain 15 152 5.7E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SMART SM00490 871 955 1.2E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SMART SM01058 517 621 3.8E-44 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Pfam PF02559 CarD-like/TRCF domain 518 620 8.1E-28 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Gene3D G3DSA:3.40.50.300 836 1001 1.1E-22 T 28-03-2018 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Pfam PF00271 Helicase conserved C-terminal domain 853 954 3.8E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SMART SM00487 645 835 1.4E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Pfam PF03461 TRCF domain 1060 1136 3.0E-21 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF143517 1050 1203 6.54E-29 T 28-03-2018 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 171 1132 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Gene3D G3DSA:3.40.50.300 383 824 6.4E-33 T 28-03-2018 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF52540 570 828 2.6E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SMART SM00982 1059 1158 7.1E-34 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF52540 395 498 4.37E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF52540 827 1035 3.04E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Pfam PF00270 DEAD/DEAH box helicase 670 811 8.5E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF52540 45 342 4.65E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 47 1143 28.064 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CP478_RS05585 b5e326e38ab181fec98dffc9750a0521 1234 SUPERFAMILY SSF141259 510 588 2.75E-17 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS08470 19f19f64f3c0b25c3d8731b924729f2a 143 Gene3D G3DSA:3.30.530.20 2 142 2.3E-18 T 28-03-2018 IPR023393 START-like domain CP478_RS08470 19f19f64f3c0b25c3d8731b924729f2a 143 SUPERFAMILY SSF55961 1 142 4.3E-21 T 28-03-2018 CP478_RS08470 19f19f64f3c0b25c3d8731b924729f2a 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 141 8.2E-24 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 Gene3D G3DSA:3.40.640.10 16 300 2.2E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 SUPERFAMILY SSF53383 16 430 3.76E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 212 226 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 19 433 3.1E-137 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 PIRSF PIRSF001434 4 437 2.2E-125 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 18 433 2.1E-207 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CP478_RS18290 9d01afb4c25975e2463bdcb4cc60d00d 449 Gene3D G3DSA:3.90.1150.10 302 449 1.6E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS12040 d1f5082d4d4035517a9d9074610be9c2 301 Pfam PF08338 Domain of unknown function (DUF1731) 250 293 6.0E-14 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CP478_RS12040 d1f5082d4d4035517a9d9074610be9c2 301 Gene3D G3DSA:3.40.50.720 5 298 4.6E-29 T 28-03-2018 CP478_RS12040 d1f5082d4d4035517a9d9074610be9c2 301 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 6 293 9.2E-104 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CP478_RS12040 d1f5082d4d4035517a9d9074610be9c2 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 215 3.3E-10 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS12040 d1f5082d4d4035517a9d9074610be9c2 301 SUPERFAMILY SSF51735 5 286 2.27E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19240 cc7d5d4c6e29f520de17b0e373f6ad0e 347 SUPERFAMILY SSF51679 5 342 3.53E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS19240 cc7d5d4c6e29f520de17b0e373f6ad0e 347 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 6 333 5.9E-156 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CP478_RS19240 cc7d5d4c6e29f520de17b0e373f6ad0e 347 Gene3D G3DSA:3.20.20.30 2 347 5.2E-69 T 28-03-2018 CP478_RS19240 cc7d5d4c6e29f520de17b0e373f6ad0e 347 Pfam PF00296 Luciferase-like monooxygenase 17 328 2.1E-71 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 SUPERFAMILY SSF47203 285 438 6.12E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 269 3.2E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 Gene3D G3DSA:1.20.140.10 269 441 6.2E-34 T 28-03-2018 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 436 2.2E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 Gene3D G3DSA:2.40.110.10 167 268 1.4E-22 T 28-03-2018 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 395 414 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS03635 70b58938be56280a0f59c8512ef643b8 542 SUPERFAMILY SSF56645 58 289 8.64E-36 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS20915 e10df5e11d5561d74b24a3a304059ff8 536 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 63 9.3E-10 T 28-03-2018 CP478_RS20915 e10df5e11d5561d74b24a3a304059ff8 536 Gene3D G3DSA:3.50.50.60 2 533 1.6E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20915 e10df5e11d5561d74b24a3a304059ff8 536 SUPERFAMILY SSF51905 372 400 1.05E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20915 e10df5e11d5561d74b24a3a304059ff8 536 SUPERFAMILY SSF51905 1 336 1.05E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12510 2d08e61c1b78223cf0c3c7d0c57ee10c 307 Gene3D G3DSA:3.20.20.140 8 307 3.5E-40 T 28-03-2018 CP478_RS12510 2d08e61c1b78223cf0c3c7d0c57ee10c 307 Pfam PF04909 Amidohydrolase 11 305 8.2E-47 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS12510 2d08e61c1b78223cf0c3c7d0c57ee10c 307 SUPERFAMILY SSF51556 9 306 1.28E-53 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS17640 1a3e3a0e221ec996d006bb9259daf831 321 Gene3D G3DSA:3.40.50.10330 1 131 3.8E-25 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CP478_RS17640 1a3e3a0e221ec996d006bb9259daf831 321 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 119 4.2E-24 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CP478_RS17640 1a3e3a0e221ec996d006bb9259daf831 321 SMART SM00046 2 130 2.9E-27 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CP478_RS17640 1a3e3a0e221ec996d006bb9259daf831 321 SUPERFAMILY SSF111331 1 316 9.59E-48 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 85 669 2.7E-192 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 203 245 2.1E-12 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 SMART SM00863 189 245 2.4E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 SUPERFAMILY SSF55186 78 266 1.2E-51 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 79 675 33.346 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 364 570 3.0E-38 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Pfam PF03129 Anticodon binding domain 582 670 1.1E-15 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 SUPERFAMILY SSF52954 570 678 3.17E-26 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Gene3D G3DSA:3.30.930.10 249 568 2.0E-105 T 28-03-2018 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Gene3D G3DSA:3.40.50.800 569 680 2.6E-21 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Gene3D G3DSA:3.30.980.10 200 248 1.7E-13 T 28-03-2018 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Gene3D G3DSA:3.30.54.20 157 199 2.7E-15 T 28-03-2018 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 SUPERFAMILY SSF55681 269 566 2.11E-92 T 28-03-2018 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 Gene3D G3DSA:3.30.980.10 81 156 2.8E-18 T 28-03-2018 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 PRINTS PR01047 Threonyl-tRNA synthetase signature 369 397 1.4E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 533 1.4E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 PRINTS PR01047 Threonyl-tRNA synthetase signature 402 425 1.4E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 PRINTS PR01047 Threonyl-tRNA synthetase signature 575 587 1.4E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS14320 628d6a6cea4b3e563ac294473f9e7e52 692 PRINTS PR01047 Threonyl-tRNA synthetase signature 548 561 1.4E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CP478_RS13020 bc71520b6f27b95f4fa7c63592483017 390 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 23 352 2.4E-76 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CP478_RS13020 bc71520b6f27b95f4fa7c63592483017 390 Pfam PF04055 Radical SAM superfamily 26 197 1.1E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS13020 bc71520b6f27b95f4fa7c63592483017 390 SMART SM00729 20 243 1.3E-51 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS13020 bc71520b6f27b95f4fa7c63592483017 390 SUPERFAMILY SSF102114 13 389 1.31E-107 T 28-03-2018 CP478_RS13020 bc71520b6f27b95f4fa7c63592483017 390 Gene3D G3DSA:3.20.20.70 20 309 3.3E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 Pfam PF01966 HD domain 72 221 1.0E-20 T 28-03-2018 IPR006674 HD domain CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 35 411 3.1E-72 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 SMART SM00471 68 231 6.3E-15 T 28-03-2018 IPR003607 HD/PDEase domain CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 Gene3D G3DSA:1.10.3410.10 213 350 3.8E-25 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 3 423 31.626 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 Pfam PF13286 Phosphohydrolase-associated domain 330 417 1.9E-15 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 SUPERFAMILY SSF109604 35 172 1.5E-55 T 28-03-2018 CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 SUPERFAMILY SSF109604 202 241 1.5E-55 T 28-03-2018 CP478_RS12790 50edb06c5a6387ccb3a7e16015c92065 431 Gene3D G3DSA:1.10.3210.10 10 212 3.5E-59 T 28-03-2018 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 SUPERFAMILY SSF51905 425 470 8.58E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 SUPERFAMILY SSF51905 2 301 8.58E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 56 1.8E-12 T 28-03-2018 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 2.0E-5 T 28-03-2018 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 2.0E-5 T 28-03-2018 CP478_RS07830 31cab2049f5d5f10dd4af63898a72fd9 473 Gene3D G3DSA:3.50.50.60 2 473 3.6E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Gene3D G3DSA:3.90.190.20 315 483 6.2E-36 T 28-03-2018 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Gene3D G3DSA:3.40.1190.10 96 309 1.7E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 9 484 31.555 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 SUPERFAMILY SSF53244 312 397 4.58E-31 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 SUPERFAMILY SSF53244 437 483 4.58E-31 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Gene3D G3DSA:3.40.50.720 11 95 1.1E-13 T 28-03-2018 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 482 1.3E-149 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 SUPERFAMILY SSF53623 112 308 3.4E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Pfam PF08245 Mur ligase middle domain 118 290 1.2E-20 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 SUPERFAMILY SSF51984 8 95 1.0E-12 T 28-03-2018 CP478_RS11725 28b6c159398f0a63151355e0802ad63f 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 381 7.4E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 194 34.496 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 Pfam PF03719 Ribosomal protein S5, C-terminal domain 118 188 6.4E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 Pfam PF00333 Ribosomal protein S5, N-terminal domain 44 106 1.1E-27 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 Gene3D G3DSA:3.30.230.10 107 197 1.4E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 Gene3D G3DSA:3.30.160.20 41 102 2.4E-26 T 28-03-2018 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 SUPERFAMILY SSF54211 110 189 6.07E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 SUPERFAMILY SSF54768 40 107 2.41E-22 T 28-03-2018 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 40 194 3.4E-69 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CP478_RS03905 bf99e7d80fabf95e81fe3a92ec8ddbb4 220 ProSitePatterns PS00585 Ribosomal protein S5 signature. 59 91 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Gene3D G3DSA:3.40.50.620 7 129 1.7E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 323 1.9E-75 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 SUPERFAMILY SSF52374 7 319 1.15E-97 T 28-03-2018 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Gene3D G3DSA:1.10.8.70 337 381 4.8E-4 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Gene3D G3DSA:1.10.1160.10 252 335 5.3E-27 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Gene3D G3DSA:3.40.50.620 130 251 2.4E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 24 35 4.2E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 10 22 4.2E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 52 4.2E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 4.2E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 4.2E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 6 482 8.3E-130 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 6 484 30.334 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 SUPERFAMILY SSF48163 320 483 2.88E-35 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CP478_RS16365 993811ac0668d4d3d283d97f8c1ec910 490 Gene3D G3DSA:1.10.10.350 388 490 2.4E-26 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CP478_RS04375 08ee86bcbe246a69e54cf898b681f97f 532 Pfam PF17102 Stealth protein CR3, conserved region 3 389 435 9.9E-19 T 28-03-2018 IPR031357 Stealth protein CR3, conserved region 3 CP478_RS04375 08ee86bcbe246a69e54cf898b681f97f 532 Pfam PF11380 Stealth protein CR2, conserved region 2 239 342 7.0E-40 T 28-03-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 CP478_RS04375 08ee86bcbe246a69e54cf898b681f97f 532 Pfam PF17101 Stealth protein CR1, conserved region 1 201 223 1.0E-9 T 28-03-2018 IPR031358 Stealth protein CR1, conserved region 1 CP478_RS04375 08ee86bcbe246a69e54cf898b681f97f 532 Pfam PF17103 Stealth protein CR4, conserved region 4 465 518 1.3E-16 T 28-03-2018 IPR031356 Stealth protein CR4, conserved region 4 CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 Gene3D G3DSA:3.10.129.10 163 284 3.6E-25 T 28-03-2018 CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 Pfam PF13452 N-terminal half of MaoC dehydratase 9 138 7.6E-12 T 28-03-2018 CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 SUPERFAMILY SSF54637 164 281 6.93E-28 T 28-03-2018 IPR029069 HotDog domain CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 Gene3D G3DSA:3.10.129.10 12 162 1.2E-33 T 28-03-2018 CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 SUPERFAMILY SSF54637 9 159 1.43E-37 T 28-03-2018 IPR029069 HotDog domain CP478_RS19340 590c37ea8a7208c608c999ad7d47d623 286 Pfam PF01575 MaoC like domain 163 271 3.3E-26 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 SUPERFAMILY SSF56801 5 569 2.35E-94 T 28-03-2018 CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 Gene3D G3DSA:2.30.38.10 376 459 1.3E-20 T 28-03-2018 CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 Pfam PF00501 AMP-binding enzyme 11 466 1.1E-71 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 Gene3D G3DSA:3.40.50.980 174 351 1.9E-25 T 28-03-2018 CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 Gene3D G3DSA:3.30.300.30 460 569 1.1E-13 T 28-03-2018 CP478_RS06495 be8625db696baa5ffb90a493cd567504 578 Gene3D G3DSA:3.40.50.980 1 173 4.1E-29 T 28-03-2018 CP478_RS21010 66506baf0370985283d5d9f75b5e450f 148 Pfam PF01548 Transposase 7 145 2.2E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CP478_RS18330 66506baf0370985283d5d9f75b5e450f 148 Pfam PF01548 Transposase 7 145 2.2E-12 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CP478_RS01045 ad1e93c0310151866eb50896b96267d3 413 Pfam PF07690 Major Facilitator Superfamily 227 397 1.5E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS01045 ad1e93c0310151866eb50896b96267d3 413 Pfam PF07690 Major Facilitator Superfamily 26 222 4.4E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS01045 ad1e93c0310151866eb50896b96267d3 413 SUPERFAMILY SSF103473 10 396 3.27E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS01045 ad1e93c0310151866eb50896b96267d3 413 Gene3D G3DSA:1.20.1250.20 214 400 2.0E-14 T 28-03-2018 CP478_RS01045 ad1e93c0310151866eb50896b96267d3 413 Gene3D G3DSA:1.20.1250.20 18 213 2.0E-22 T 28-03-2018 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 Gene3D G3DSA:1.10.1740.10 1 85 5.4E-21 T 28-03-2018 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 SUPERFAMILY SSF88946 6 105 9.81E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 Pfam PF04542 Sigma-70 region 2 30 94 1.1E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 Gene3D G3DSA:1.10.10.10 86 180 1.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 Pfam PF08281 Sigma-70, region 4 123 174 3.0E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 SUPERFAMILY SSF88659 118 175 2.09E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 174 3.9E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11280 688a0aa7b2e663cc2a4871d70a0801a8 185 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 50 81 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS11665 55015886ef471a1d10945eb4a76b19f7 352 SUPERFAMILY SSF53271 138 344 2.16E-50 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS11665 55015886ef471a1d10945eb4a76b19f7 352 Gene3D G3DSA:3.40.50.2020 125 351 1.5E-35 T 28-03-2018 CP478_RS11665 55015886ef471a1d10945eb4a76b19f7 352 Gene3D G3DSA:3.20.20.140 2 124 1.5E-5 T 28-03-2018 CP478_RS11665 55015886ef471a1d10945eb4a76b19f7 352 SUPERFAMILY SSF51556 9 78 1.9E-9 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS11665 55015886ef471a1d10945eb4a76b19f7 352 Pfam PF00156 Phosphoribosyl transferase domain 144 331 3.5E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS01760 bd60778888f9b04a5ca2cdacfa0c5607 208 Pfam PF08241 Methyltransferase domain 55 151 4.9E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS01760 bd60778888f9b04a5ca2cdacfa0c5607 208 Gene3D G3DSA:3.40.50.150 24 207 4.5E-30 T 28-03-2018 CP478_RS01760 bd60778888f9b04a5ca2cdacfa0c5607 208 SUPERFAMILY SSF53335 26 203 2.52E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 SUPERFAMILY SSF52540 506 585 9.81E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 SUPERFAMILY SSF52540 383 438 9.81E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 SUPERFAMILY SSF52540 32 81 9.81E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 SUPERFAMILY SSF52540 117 198 9.81E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 Pfam PF04851 Type III restriction enzyme, res subunit 15 196 6.1E-17 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 Gene3D G3DSA:3.40.50.300 386 615 1.9E-6 T 28-03-2018 CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 SMART SM00487 12 227 5.7E-17 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS06470 332be291bd91bed074e5da2740cbde27 939 Gene3D G3DSA:3.40.50.300 15 210 7.2E-16 T 28-03-2018 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 SMART SM00829 8 341 5.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 SUPERFAMILY SSF50129 6 171 1.83E-53 T 28-03-2018 IPR011032 GroES-like CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 Gene3D G3DSA:3.90.180.10 1 191 6.5E-56 T 28-03-2018 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.3E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 7.4E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 Gene3D G3DSA:3.40.50.20 192 340 1.6E-20 T 28-03-2018 CP478_RS16660 4a7a3ace837ecd3ca15aa628f2fd71ec 346 SUPERFAMILY SSF51735 148 311 9.04E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 Pfam PF13186 Iron-sulfur cluster-binding domain 251 313 3.8E-5 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 Pfam PF04055 Radical SAM superfamily 26 179 1.5E-23 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 SMART SM00729 20 219 6.6E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 SUPERFAMILY SSF102114 19 323 9.81E-60 T 28-03-2018 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 Pfam PF13353 4Fe-4S single cluster domain 27 122 3.5E-5 T 28-03-2018 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 TIGRFAM TIGR03962 mycofact_rSAM: mycofactocin radical SAM maturase 9 348 3.7E-206 T 28-03-2018 IPR023913 Mycofactocin, radical SAM peptide maturase CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 251 331 1.1E-13 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 Gene3D G3DSA:3.20.20.70 6 308 2.0E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 PIRSF PIRSF037420 241 357 1.3E-10 T 28-03-2018 CP478_RS03750 2a2a7f43b52066326bd284f98b51ed57 391 PIRSF PIRSF037420 9 236 6.5E-53 T 28-03-2018 CP478_RS00860 a311bf1f5c333ce387619b43473964c4 475 SUPERFAMILY SSF52467 301 473 3.27E-70 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS00860 a311bf1f5c333ce387619b43473964c4 475 Gene3D G3DSA:3.40.50.1220 299 473 4.4E-81 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS00860 a311bf1f5c333ce387619b43473964c4 475 PIRSF PIRSF000204 2 474 1.5E-203 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CP478_RS00860 a311bf1f5c333ce387619b43473964c4 475 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 470 2.4E-174 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.3E-26 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 Gene3D G3DSA:4.10.520.10 1 94 1.3E-27 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 SUPERFAMILY SSF47729 1 92 2.06E-27 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.7E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.7E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.7E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CP478_RS16325 f260fcda2309f45c82f4522059592428 214 SMART SM00411 1 90 1.4E-39 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CP478_RS01925 0ec05487e252757e8ccba7998b2dbd08 145 Pfam PF11349 Protein of unknown function (DUF3151) 17 140 1.6E-58 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CP478_RS01925 0ec05487e252757e8ccba7998b2dbd08 145 PIRSF PIRSF017349 9 145 1.3E-71 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SMART SM00316 664 735 7.3E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 14 738 27.047 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 PIRSF PIRSF005499 12 752 1.5E-288 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Pfam PF01138 3' exoribonuclease family, domain 1 355 487 8.3E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Pfam PF01138 3' exoribonuclease family, domain 1 25 156 1.5E-15 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SMART SM00322 594 659 1.3E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF54791 597 683 2.89E-18 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Gene3D G3DSA:3.30.1370.10 591 658 6.8E-14 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 22 734 1.6E-264 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF50249 663 732 6.56E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF54211 13 156 1.47E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF55666 481 588 3.27E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Gene3D G3DSA:2.40.50.140 659 739 9.3E-18 T 28-03-2018 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Gene3D G3DSA:1.10.10.400 282 342 2.7E-22 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF54211 329 499 9.11E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF46915 258 356 5.62E-23 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 10 733 0.0 T 28-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Gene3D G3DSA:3.30.230.70 343 590 1.8E-52 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 SUPERFAMILY SSF55666 157 259 3.27E-25 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Pfam PF00013 KH domain 598 655 1.5E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Pfam PF00575 S1 RNA binding domain 663 732 7.3E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 274 350 1.9E-21 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CP478_RS15240 ce1b332d441f2a6124d982479e3f3de7 752 Gene3D G3DSA:3.30.230.70 23 281 2.1E-44 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Gene3D G3DSA:1.10.540.10 11 128 3.3E-38 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Gene3D G3DSA:1.20.140.10 232 392 7.2E-52 T 28-03-2018 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 SUPERFAMILY SSF56645 12 256 5.89E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 230 9.4E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Gene3D G3DSA:2.40.110.10 129 231 5.2E-32 T 28-03-2018 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 350 369 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 5.6E-36 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 391 2.7E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS13670 4f94c45c22a0b7a05e073e3fa7b1602c 394 SUPERFAMILY SSF47203 243 391 4.19E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 3.1E-44 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 160 28.359 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 PIRSF PIRSF006092 1 163 1.3E-31 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 5.8E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 Gene3D G3DSA:1.10.287.180 6 76 2.1E-25 T 28-03-2018 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 SUPERFAMILY SSF54534 82 159 1.7E-10 T 28-03-2018 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 SUPERFAMILY SSF46557 7 78 5.62E-23 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 160 7.7E-14 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CP478_RS05920 96932e563faab75c88906b893e9a09da 164 Gene3D G3DSA:3.10.50.30 77 164 1.2E-13 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CP478_RS05640 a70624de3e4dc0f5a88c2080c3572a1a 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 30 3.5E-9 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CP478_RS05640 a70624de3e4dc0f5a88c2080c3572a1a 30 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 30 1.4E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CP478_RS10840 e91b2ef75b1eddcef6b4964ab45f8018 113 ProDom PD030784 PRECURSOR SIGNAL TRANSCRIPTIONAL PROBABLE RV1990C/MT2044 REGULATORY MB3210 MB2012C 18 112 6.0E-50 T 28-03-2018 CP478_RS10840 e91b2ef75b1eddcef6b4964ab45f8018 113 Pfam PF09722 Protein of unknown function (DUF2384) 70 110 4.3E-7 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 CP478_RS10840 e91b2ef75b1eddcef6b4964ab45f8018 113 Gene3D G3DSA:1.10.260.40 4 94 8.0E-5 T 28-03-2018 CP478_RS00240 cb754d9982594c1214c3919ec2b4dfaf 244 Gene3D G3DSA:1.20.120.530 73 212 5.1E-6 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS00240 cb754d9982594c1214c3919ec2b4dfaf 244 Gene3D G3DSA:1.10.10.10 3 72 9.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00240 cb754d9982594c1214c3919ec2b4dfaf 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 8.3E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS00240 cb754d9982594c1214c3919ec2b4dfaf 244 SMART SM00345 13 71 2.0E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS00240 cb754d9982594c1214c3919ec2b4dfaf 244 SUPERFAMILY SSF46785 9 75 1.73E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00665 c91d49b7faf2fa650d0869547b331251 144 SUPERFAMILY SSF50475 10 143 1.5E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS00665 c91d49b7faf2fa650d0869547b331251 144 Gene3D G3DSA:2.30.110.10 8 144 1.3E-25 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS00665 c91d49b7faf2fa650d0869547b331251 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 106 4.0E-18 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS00665 c91d49b7faf2fa650d0869547b331251 144 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 3 143 2.6E-68 T 28-03-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable CP478_RS09030 ed5570004b39719443a340926343cad4 831 SMART SM00873 222 395 2.1E-73 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:2.40.50.140 43 140 2.4E-30 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 830 1.5E-161 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Pfam PF03147 Ferredoxin-fold anticodon binding domain 737 830 1.4E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:3.50.40.10 209 406 1.0E-61 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF55681 626 725 7.45E-34 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF55681 480 596 7.45E-34 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF50249 49 197 2.4E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS09030 ed5570004b39719443a340926343cad4 831 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 824 41.082 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SMART SM00896 737 830 4.7E-41 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Pfam PF03484 tRNA synthetase B5 domain 423 484 9.6E-15 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF56037 213 404 1.39E-58 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Pfam PF01588 Putative tRNA binding domain 50 152 1.6E-19 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:3.30.930.10 500 726 2.5E-30 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:3.30.56.10 141 191 2.6E-7 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:3.30.70.380 734 830 9.8E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Pfam PF03483 B3/4 domain 224 395 2.0E-56 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 Gene3D G3DSA:3.30.56.10 415 484 3.8E-17 T 28-03-2018 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF54991 735 830 4.18E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SMART SM00874 416 484 1.2E-19 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CP478_RS09030 ed5570004b39719443a340926343cad4 831 SUPERFAMILY SSF46955 416 488 3.2E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 Pfam PF00027 Cyclic nucleotide-binding domain 42 124 1.2E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 312 344 - T 28-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 SUPERFAMILY SSF52151 305 512 8.2E-42 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 Gene3D G3DSA:3.40.1090.10 300 527 5.1E-32 T 28-03-2018 CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 SMART SM00100 24 138 3.1E-26 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 Gene3D G3DSA:2.60.120.10 8 150 2.6E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 SUPERFAMILY SSF51206 16 142 2.09E-26 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS14065 73dabbffa03d9d70ecc1096cab662368 583 Pfam PF01734 Patatin-like phospholipase 309 467 1.2E-20 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS13640 e3c4004ff87a9991177acbcb556632da 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 134 15.262 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS13640 e3c4004ff87a9991177acbcb556632da 141 SUPERFAMILY SSF88723 3 136 6.73E-12 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13640 e3c4004ff87a9991177acbcb556632da 141 Pfam PF01850 PIN domain 3 122 1.5E-6 T 28-03-2018 IPR002716 PIN domain CP478_RS13640 e3c4004ff87a9991177acbcb556632da 141 Gene3D G3DSA:3.40.50.1010 2 138 2.3E-10 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13640 e3c4004ff87a9991177acbcb556632da 141 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 139 1.7E-41 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 Gene3D G3DSA:3.30.1310.10 7 122 4.5E-37 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 Pfam PF02575 YbaB/EbfC DNA-binding family 12 100 1.2E-31 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 PIRSF PIRSF004555 3 123 4.5E-45 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 5 92 4.1E-23 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 21.536 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS20300 c1def061a074793d5be42b5458bf75b6 133 SUPERFAMILY SSF82607 12 103 7.98E-29 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS19075 9535e0fe5380b4b0e91adcf9263a5dc0 277 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 84 96 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site CP478_RS19075 9535e0fe5380b4b0e91adcf9263a5dc0 277 SUPERFAMILY SSF53474 9 244 5.98E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19075 9535e0fe5380b4b0e91adcf9263a5dc0 277 Pfam PF07859 alpha/beta hydrolase fold 16 222 1.5E-42 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS19075 9535e0fe5380b4b0e91adcf9263a5dc0 277 Gene3D G3DSA:3.40.50.1820 2 258 1.5E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15045 e3c8520055748e6b5a2c1a8dcee4d11c 112 Pfam PF13560 Helix-turn-helix domain 10 65 8.9E-12 T 28-03-2018 CP478_RS15045 e3c8520055748e6b5a2c1a8dcee4d11c 112 Gene3D G3DSA:1.10.260.40 2 79 3.1E-14 T 28-03-2018 CP478_RS15045 e3c8520055748e6b5a2c1a8dcee4d11c 112 SMART SM00530 12 67 6.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS15045 e3c8520055748e6b5a2c1a8dcee4d11c 112 SUPERFAMILY SSF47413 5 72 1.01E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS09635 14d485dd38355f64408d8e9facc49aad 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 92 1.6E-17 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS09635 14d485dd38355f64408d8e9facc49aad 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 26 106 8.1E-22 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS09635 14d485dd38355f64408d8e9facc49aad 119 SUPERFAMILY SSF69118 16 109 2.22E-28 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS09635 14d485dd38355f64408d8e9facc49aad 119 Gene3D G3DSA:1.20.1290.10 3 118 7.3E-24 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Gene3D G3DSA:1.10.1240.10 630 717 8.6E-32 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Gene3D G3DSA:3.10.196.10 960 1192 7.5E-61 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SUPERFAMILY SSF51717 344 615 4.84E-75 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Gene3D G3DSA:3.40.50.280 718 897 3.7E-44 T 28-03-2018 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 PIRSF PIRSF000381 6 1192 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Pfam PF02574 Homocysteine S-methyltransferase 23 312 5.4E-59 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SUPERFAMILY SSF56507 901 1192 2.22E-87 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 978 1192 2.5E-32 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Pfam PF02607 B12 binding domain 645 717 5.1E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SMART SM01018 642 724 7.4E-42 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 TIGRFAM TIGR02082 metH: methionine synthase 17 1192 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SUPERFAMILY SSF82282 12 386 7.19E-101 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SUPERFAMILY SSF47644 641 723 3.92E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Pfam PF02310 B12 binding domain 731 848 6.8E-19 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Gene3D G3DSA:3.20.20.330 8 324 3.9E-85 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Gene3D G3DSA:3.20.20.20 332 629 7.2E-47 T 28-03-2018 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 SUPERFAMILY SSF52242 725 862 6.67E-38 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS11555 6a9d175ea4420daa81ece47eb6d4943d 1192 Pfam PF00809 Pterin binding enzyme 347 583 5.3E-48 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 SMART SM01400 12 128 9.4E-70 T 28-03-2018 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 Gene3D G3DSA:3.40.50.2020 162 315 3.1E-38 T 28-03-2018 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 SUPERFAMILY SSF53271 77 314 1.58E-59 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 3.1E-20 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.4E-45 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 Gene3D G3DSA:3.40.50.2020 9 161 2.3E-64 T 28-03-2018 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 45.096 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CP478_RS05565 579fb95544722fc81d68a4f8df044db1 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 323 6.6E-121 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CP478_RS18995 815e3d847d6b81178c0fedb82bbcbe45 177 Gene3D G3DSA:2.60.120.10 48 170 3.4E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS18995 815e3d847d6b81178c0fedb82bbcbe45 177 Pfam PF07883 Cupin domain 87 154 7.3E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CP478_RS18995 815e3d847d6b81178c0fedb82bbcbe45 177 SUPERFAMILY SSF51182 30 162 2.61E-29 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS18995 815e3d847d6b81178c0fedb82bbcbe45 177 SMART SM00835 52 173 0.0025 T 28-03-2018 IPR006045 Cupin 1 GO:0045735 CP478_RS00245 ee8f39a97fcd31067945895d3ca8c9f0 264 TIGRFAM TIGR03856 F420_MSMEG_2906: probable F420-dependent oxidoreductase, MSMEG_2906 family 11 262 2.6E-134 T 28-03-2018 IPR022480 F420-dependent oxidoreductase, MSMEG2906 CP478_RS00245 ee8f39a97fcd31067945895d3ca8c9f0 264 Pfam PF00296 Luciferase-like monooxygenase 12 214 2.2E-32 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS00245 ee8f39a97fcd31067945895d3ca8c9f0 264 SUPERFAMILY SSF51679 11 220 9.76E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS00245 ee8f39a97fcd31067945895d3ca8c9f0 264 Gene3D G3DSA:3.20.20.30 5 253 3.8E-47 T 28-03-2018 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Gene3D G3DSA:3.40.50.300 344 800 4.5E-46 T 28-03-2018 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 336 1.8E-38 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Gene3D G3DSA:3.90.320.10 877 1071 9.9E-17 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 SUPERFAMILY SSF52980 934 1057 4.45E-7 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Pfam PF13361 UvrD-like helicase C-terminal domain 391 503 6.6E-10 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Pfam PF13361 UvrD-like helicase C-terminal domain 653 770 2.8E-17 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Pfam PF12705 PD-(D/E)XK nuclease superfamily 919 1069 2.5E-12 T 28-03-2018 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 Gene3D G3DSA:3.40.50.300 18 343 2.7E-44 T 28-03-2018 CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 SUPERFAMILY SSF52540 537 701 2.32E-105 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 SUPERFAMILY SSF52540 748 794 2.32E-105 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 SUPERFAMILY SSF52540 21 191 2.32E-105 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17545 5f31bd28f33dddb3a002452eaf2b8e18 1101 SUPERFAMILY SSF52540 224 502 2.32E-105 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS10640 a2f78e9d6f7fcd0eef793625a9edac9a 149 Pfam PF01381 Helix-turn-helix 44 91 3.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS10640 a2f78e9d6f7fcd0eef793625a9edac9a 149 Gene3D G3DSA:3.30.1190.10 58 106 5.3E-11 T 28-03-2018 CP478_RS10640 a2f78e9d6f7fcd0eef793625a9edac9a 149 SMART SM00530 41 96 2.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS10640 a2f78e9d6f7fcd0eef793625a9edac9a 149 SUPERFAMILY SSF47413 36 100 2.17E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS10640 a2f78e9d6f7fcd0eef793625a9edac9a 149 Gene3D G3DSA:1.10.10.10 22 57 3.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 188 205 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 5 16 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 188 209 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 284 297 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 361 373 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 306 322 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PRINTS PR00471 Acetate kinase family signature 158 171 4.2E-44 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 SUPERFAMILY SSF53067 142 382 1.73E-80 T 28-03-2018 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 Gene3D G3DSA:3.30.420.40 181 385 6.7E-72 T 28-03-2018 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 Hamap MF_00020 Acetate kinase [ackA]. 1 383 159.222 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 TIGRFAM TIGR00016 ackA: acetate kinase 2 379 1.2E-122 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 SUPERFAMILY SSF53067 4 180 1.72E-56 T 28-03-2018 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 Pfam PF00871 Acetokinase family 5 374 5.0E-127 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 Gene3D G3DSA:3.30.420.40 4 180 2.2E-63 T 28-03-2018 CP478_RS02180 a9fa243dbd2635bd0ee0803654b85683 385 PIRSF PIRSF000722 1 383 7.8E-126 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CP478_RS01435 564fc522c34949c64c1199adb3e0ec90 1209 Gene3D G3DSA:3.30.420.40 265 653 0.023 T 28-03-2018 CP478_RS01435 564fc522c34949c64c1199adb3e0ec90 1209 Gene3D G3DSA:3.30.420.40 7 207 0.06 T 28-03-2018 CP478_RS01435 564fc522c34949c64c1199adb3e0ec90 1209 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 8 183 2.4E-58 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CP478_RS01435 564fc522c34949c64c1199adb3e0ec90 1209 Pfam PF02538 Hydantoinase B/oxoprolinase 694 1200 1.1E-203 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CP478_RS01435 564fc522c34949c64c1199adb3e0ec90 1209 Pfam PF01968 Hydantoinase/oxoprolinase 202 489 5.7E-115 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CP478_RS20815 604c079f1fdd3215f1375bd6ac1f8997 504 Pfam PF00934 PE family 2 93 2.8E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS20815 604c079f1fdd3215f1375bd6ac1f8997 504 SUPERFAMILY SSF140459 8 84 8.37E-24 T 28-03-2018 CP478_RS20815 604c079f1fdd3215f1375bd6ac1f8997 504 Gene3D G3DSA:1.10.287.1060 2 102 4.0E-5 T 28-03-2018 CP478_RS17690 bad74ab7a96f29708f218ccfb52d2cb0 72 SUPERFAMILY SSF55826 3 46 1.44E-11 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS17690 bad74ab7a96f29708f218ccfb52d2cb0 72 Gene3D G3DSA:3.90.960.10 1 52 9.1E-12 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS17690 bad74ab7a96f29708f218ccfb52d2cb0 72 Pfam PF04073 Aminoacyl-tRNA editing domain 3 46 1.4E-6 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CP478_RS05870 ae149051746a04159c831e0ec22235f1 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 256 3.6E-81 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS05870 ae149051746a04159c831e0ec22235f1 257 Gene3D G3DSA:1.10.12.10 218 255 7.3E-24 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS05870 ae149051746a04159c831e0ec22235f1 257 Gene3D G3DSA:3.90.226.10 2 217 2.4E-75 T 28-03-2018 CP478_RS05870 ae149051746a04159c831e0ec22235f1 257 SUPERFAMILY SSF52096 1 256 1.19E-91 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS05870 ae149051746a04159c831e0ec22235f1 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 SUPERFAMILY SSF53254 1 194 2.69E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 Gene3D G3DSA:3.40.50.1240 3 221 1.5E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 PIRSF PIRSF000709 1 182 3.2E-11 T 28-03-2018 CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 SMART SM00855 5 166 3.8E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS13205 c0e92b596f2b64d24893445300db3efc 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 213 1.4E-49 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 Pfam PF01565 FAD binding domain 40 178 6.7E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 Gene3D G3DSA:3.30.465.10 93 236 6.5E-38 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 SUPERFAMILY SSF55103 219 457 1.42E-50 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 SUPERFAMILY SSF56176 2 213 2.15E-62 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 454 1.9E-58 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 Gene3D G3DSA:3.30.43.10 1 92 2.6E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS12390 db744fe83e1ebf193e709146c9d7ef07 459 Gene3D G3DSA:1.10.45.10 416 455 1.4E-11 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 Pfam PF00588 SpoU rRNA Methylase family 161 300 2.3E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 70 144 3.2E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 Gene3D G3DSA:3.40.1280.10 142 321 8.8E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 SUPERFAMILY SSF55315 60 142 1.53E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 SMART SM00967 69 145 1.6E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 Gene3D G3DSA:3.30.1330.30 44 141 1.0E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 SUPERFAMILY SSF75217 133 311 3.14E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS19560 74e989f73153b1d08f230451c31c47d8 322 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 67 307 2.6E-56 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 SUPERFAMILY SSF109998 246 436 5.69E-38 T 28-03-2018 IPR027304 Trigger factor/SurA domain CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 PIRSF PIRSF003095 1 445 1.2E-118 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 SUPERFAMILY SSF102735 2 127 6.41E-33 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 Gene3D G3DSA:3.30.70.1050 1 117 3.9E-33 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 TIGRFAM TIGR00115 tig: trigger factor 12 416 7.6E-112 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 Pfam PF05697 Bacterial trigger factor protein (TF) 2 144 8.9E-37 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 418 1.7E-39 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 Gene3D G3DSA:1.10.3120.10 210 396 3.2E-39 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 SUPERFAMILY SSF54534 133 244 1.39E-20 T 28-03-2018 CP478_RS13450 30953309c9c1c9397c78b16a183dbc72 466 Hamap MF_00303 Trigger factor [tig]. 1 424 18.559 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 SUPERFAMILY SSF52540 122 301 1.54E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 SMART SM00322 19 82 6.1E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 Gene3D G3DSA:3.40.50.300 122 330 1.0E-29 T 28-03-2018 CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 Pfam PF02562 PhoH-like protein 126 328 2.3E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 SUPERFAMILY SSF54791 18 82 1.22E-5 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CP478_RS12915 7bede1c097ea9ef6dc737673c04d9b1b 352 Gene3D G3DSA:3.30.1370.10 9 96 5.4E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 407 444 7.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 309 346 2.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 357 395 1.9E-12 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 337 376 1.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 398 435 1.9E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF01469 Pentapeptide repeats (8 copies) 317 355 1.5E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Pfam PF00823 PPE family 5 161 1.5E-57 T 28-03-2018 IPR000030 PPE family CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 Gene3D G3DSA:1.10.287.1060 22 106 1.4E-4 T 28-03-2018 CP478_RS10440 836bf86d28c8b374589491fdea0d4a81 987 SUPERFAMILY SSF140459 3 171 2.28E-56 T 28-03-2018 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 358 372 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 338 355 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 154 172 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 182 197 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 381 399 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 5.8E-47 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 Pfam PF02274 Amidinotransferase 19 399 5.7E-103 T 28-03-2018 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 Hamap MF_00242 Arginine deiminase [arcA]. 2 402 41.298 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 SUPERFAMILY SSF55909 5 402 1.41E-114 T 28-03-2018 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 Gene3D G3DSA:3.75.10.10 4 400 1.4E-91 T 28-03-2018 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 PIRSF PIRSF006356 1 402 1.6E-144 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS05480 da158c75ed567c0aedb1db89d494639a 402 TIGRFAM TIGR01078 arcA: arginine deiminase 8 401 8.2E-162 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 436 455 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Gene3D G3DSA:2.40.110.10 227 323 1.7E-18 T 28-03-2018 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Gene3D G3DSA:1.10.540.10 94 222 3.3E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 228 314 3.2E-12 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 SUPERFAMILY SSF47203 338 465 8.54E-36 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 111 220 7.7E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 337 464 7.2E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 Gene3D G3DSA:1.20.140.10 324 467 7.8E-35 T 28-03-2018 CP478_RS17195 353aab17a9d5efe1b5511ee3df35e807 468 SUPERFAMILY SSF56645 104 327 1.7E-44 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Gene3D G3DSA:2.40.30.10 11 112 5.6E-21 T 28-03-2018 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 SUPERFAMILY SSF52343 112 245 3.4E-31 T 28-03-2018 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 SUPERFAMILY SSF63380 14 121 1.28E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 274 347 4.5E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Gene3D G3DSA:3.10.20.30 241 358 2.2E-28 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 4.3E-8 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 4.3E-8 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00410 Phenol hydroxylase reductase family signature 131 150 4.3E-8 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Pfam PF00175 Oxidoreductase NAD-binding domain 132 229 1.6E-12 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 3.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 131 150 3.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 155 164 3.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 72 79 3.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 305 313 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Gene3D G3DSA:3.40.50.80 113 240 2.8E-26 T 28-03-2018 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 SUPERFAMILY SSF54292 238 352 8.65E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS19520 ade5e89a05523580e3891e37ba79bdc2 358 Pfam PF00970 Oxidoreductase FAD-binding domain 47 121 3.4E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS08250 273e6765664a74686fe3e58d3b8be6ed 166 Gene3D G3DSA:3.40.50.150 2 108 1.3E-9 T 28-03-2018 CP478_RS08250 273e6765664a74686fe3e58d3b8be6ed 166 SUPERFAMILY SSF53335 14 63 8.67E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS08250 273e6765664a74686fe3e58d3b8be6ed 166 Pfam PF13649 Methyltransferase domain 14 64 4.5E-8 T 28-03-2018 CP478_RS05070 f9ae5eb1664af92b3a67de9ecc0b9294 324 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 23 318 7.2E-93 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CP478_RS05070 f9ae5eb1664af92b3a67de9ecc0b9294 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 317 2.0E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05070 f9ae5eb1664af92b3a67de9ecc0b9294 324 Gene3D G3DSA:1.10.3720.10 15 315 3.4E-33 T 28-03-2018 CP478_RS05070 f9ae5eb1664af92b3a67de9ecc0b9294 324 SUPERFAMILY SSF161098 45 313 7.2E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07190 2525f2ae45912bdfab99409933f30688 444 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 146 7.4E-12 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CP478_RS07190 2525f2ae45912bdfab99409933f30688 444 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 92 6.4E-9 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CP478_RS07190 2525f2ae45912bdfab99409933f30688 444 Pfam PF01610 Transposase 163 420 7.1E-71 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CP478_RS20745 2525f2ae45912bdfab99409933f30688 444 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 98 146 7.4E-12 T 28-03-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain CP478_RS20745 2525f2ae45912bdfab99409933f30688 444 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 47 92 6.4E-9 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CP478_RS20745 2525f2ae45912bdfab99409933f30688 444 Pfam PF01610 Transposase 163 420 7.1E-71 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 Pfam PF13439 Glycosyltransferase Family 4 65 245 5.7E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 Gene3D G3DSA:3.40.50.2000 60 255 6.1E-22 T 28-03-2018 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 45 449 50.482 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 SUPERFAMILY SSF53756 46 445 1.26E-82 T 28-03-2018 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 Gene3D G3DSA:3.40.50.2000 256 428 9.4E-43 T 28-03-2018 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 Pfam PF00534 Glycosyl transferases group 1 252 407 2.1E-34 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS02590 74db79cbae645a517da9cf97aaa6c001 480 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 46 445 6.9E-203 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS02210 6d937515e9c89ff4ef43a0954e1c6a7a 340 Gene3D G3DSA:3.40.50.20 1 169 2.9E-9 T 28-03-2018 CP478_RS02210 6d937515e9c89ff4ef43a0954e1c6a7a 340 Pfam PF01266 FAD dependent oxidoreductase 10 330 1.3E-48 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CP478_RS02210 6d937515e9c89ff4ef43a0954e1c6a7a 340 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 11 334 2.0E-109 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CP478_RS02210 6d937515e9c89ff4ef43a0954e1c6a7a 340 SUPERFAMILY SSF51905 11 268 5.96E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02210 6d937515e9c89ff4ef43a0954e1c6a7a 340 Gene3D G3DSA:3.30.9.10 170 293 1.0E-26 T 28-03-2018 CP478_RS06650 edd1c5a513736e5ebb6b0c1886ce1c04 110 Pfam PF00934 PE family 1 83 1.6E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06650 edd1c5a513736e5ebb6b0c1886ce1c04 110 SUPERFAMILY SSF140459 2 74 2.07E-24 T 28-03-2018 CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 SMART SM01120 1 132 1.5E-9 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 1 470 1.6E-124 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 SMART SM01121 161 470 1.6E-87 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 Pfam PF02734 DAK2 domain 2 131 2.4E-17 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 Pfam PF13684 Dihydroxyacetone kinase family 162 470 1.4E-74 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CP478_RS16260 0da55c04c03ff5e683a42c907dfb7aba 470 SUPERFAMILY SSF101473 2 133 3.66E-14 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CP478_RS10335 6789088cdf630c3ab9ab6298d3b5504a 102 SUPERFAMILY SSF89957 3 98 2.62E-28 T 28-03-2018 IPR029756 MTH1187/YkoF-like CP478_RS10335 6789088cdf630c3ab9ab6298d3b5504a 102 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 97 6.8E-16 T 28-03-2018 IPR002767 Thiamine-binding protein CP478_RS10335 6789088cdf630c3ab9ab6298d3b5504a 102 Gene3D G3DSA:3.30.70.930 1 97 1.1E-30 T 28-03-2018 IPR029756 MTH1187/YkoF-like CP478_RS10335 6789088cdf630c3ab9ab6298d3b5504a 102 Pfam PF01910 Thiamine-binding protein 5 95 1.5E-29 T 28-03-2018 IPR002767 Thiamine-binding protein CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 Pfam PF13456 Reverse transcriptase-like 7 129 4.0E-24 T 28-03-2018 CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 Gene3D G3DSA:3.30.420.10 2 162 8.8E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 167 359 5.9E-54 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 PIRSF PIRSF036922 1 364 1.6E-189 T 28-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 SUPERFAMILY SSF53254 164 363 1.7E-50 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 SUPERFAMILY SSF53098 3 127 5.44E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 Gene3D G3DSA:3.40.50.1240 163 364 7.0E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS12115 a98f944fd863e23a6e3d56578a972f48 364 SMART SM00855 166 320 5.3E-15 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS13095 aad6fdda87844b786a8bb28b0a780b1e 356 SUPERFAMILY SSF53850 56 351 5.24E-52 T 28-03-2018 CP478_RS13095 aad6fdda87844b786a8bb28b0a780b1e 356 Pfam PF13531 Bacterial extracellular solute-binding protein 59 303 2.5E-33 T 28-03-2018 CP478_RS13095 aad6fdda87844b786a8bb28b0a780b1e 356 Gene3D G3DSA:3.40.190.10 158 353 1.6E-37 T 28-03-2018 CP478_RS13095 aad6fdda87844b786a8bb28b0a780b1e 356 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 74 341 2.7E-47 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CP478_RS13095 aad6fdda87844b786a8bb28b0a780b1e 356 Gene3D G3DSA:3.40.190.10 57 157 3.4E-15 T 28-03-2018 CP478_RS02685 9824b47948187199aab4e26f29de43b5 376 Pfam PF01370 NAD dependent epimerase/dehydratase family 26 208 1.7E-19 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS02685 9824b47948187199aab4e26f29de43b5 376 SUPERFAMILY SSF51735 23 337 3.36E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02685 9824b47948187199aab4e26f29de43b5 376 Gene3D G3DSA:3.40.50.720 21 340 2.8E-37 T 28-03-2018 CP478_RS05930 e431fec0f23e0247a28fade1c808fff6 288 Gene3D G3DSA:3.40.50.10320 1 288 1.1E-71 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS05930 e431fec0f23e0247a28fade1c808fff6 288 SUPERFAMILY SSF102588 4 287 1.1E-72 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS05930 e431fec0f23e0247a28fade1c808fff6 288 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 7 287 50.444 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CP478_RS05930 e431fec0f23e0247a28fade1c808fff6 288 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 4 286 1.4E-154 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CP478_RS05930 e431fec0f23e0247a28fade1c808fff6 288 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 152 5.9E-26 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 ProSitePatterns PS01270 Band 7 protein family signature. 138 166 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 Pfam PF01145 SPFH domain / Band 7 family 29 208 2.4E-30 T 28-03-2018 IPR001107 Band 7 domain CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 158 176 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 177 198 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 31 53 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 114 131 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 79 100 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 PRINTS PR00721 Stomatin signature 134 157 2.3E-31 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 SMART SM00244 24 182 4.3E-56 T 28-03-2018 IPR001107 Band 7 domain CP478_RS08150 71ebd7cfda2903249c166b839c99b4d9 381 SUPERFAMILY SSF117892 55 189 3.66E-39 T 28-03-2018 IPR001107 Band 7 domain CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 SUPERFAMILY SSF51246 322 402 6.91E-18 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 SUPERFAMILY SSF56059 116 316 4.77E-57 T 28-03-2018 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 Gene3D G3DSA:3.30.470.20 197 395 2.9E-46 T 28-03-2018 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 20 384 3.0E-134 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 SMART SM01209 115 276 0.0022 T 28-03-2018 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 Gene3D G3DSA:3.30.1490.20 99 196 6.0E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 SUPERFAMILY SSF52440 19 111 4.75E-22 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 Gene3D G3DSA:3.40.50.20 18 98 6.2E-23 T 28-03-2018 CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 Pfam PF02222 ATP-grasp domain 125 297 5.2E-57 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CP478_RS17960 baf6cf0710748d14f23a168a9fb301c5 429 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 19 379 39.536 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Gene3D G3DSA:3.40.50.800 361 462 2.0E-23 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Pfam PF03129 Anticodon binding domain 369 456 9.0E-19 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 160 277 2.3E-7 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 SUPERFAMILY SSF52954 356 461 1.09E-29 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 SUPERFAMILY SSF55681 10 372 1.27E-118 T 28-03-2018 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 10 239 9.4E-79 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 28 42 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 4.8E-55 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 6 461 48.236 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Gene3D G3DSA:3.30.930.10 8 225 5.8E-51 T 28-03-2018 CP478_RS12860 3d4b6414db990978e13a5b1c46497ba6 463 Gene3D G3DSA:3.30.930.10 226 360 1.8E-37 T 28-03-2018 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SMART SM00304 235 287 5.8E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 Gene3D G3DSA:3.30.565.10 366 527 7.4E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 517 5.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SMART SM00387 408 519 6.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 Pfam PF00672 HAMP domain 235 283 5.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SUPERFAMILY SSF55874 351 521 6.81E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SMART SM00388 295 362 5.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 Pfam PF00512 His Kinase A (phospho-acceptor) domain 296 362 4.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SUPERFAMILY SSF158472 235 285 1.57E-8 T 28-03-2018 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 516 4.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 472 4.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 4.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 4.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 SUPERFAMILY SSF47384 278 362 7.06E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS17795 05c9f53f4d104e00d18bb2ae5a64d58c 567 Gene3D G3DSA:1.10.287.130 283 358 1.6E-14 T 28-03-2018 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 PIRSF PIRSF038994 36 381 2.7E-103 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 SUPERFAMILY SSF51556 52 350 3.25E-87 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 Pfam PF01979 Amidohydrolase family 48 379 3.3E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 Gene3D G3DSA:3.20.20.140 67 352 5.7E-100 T 28-03-2018 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 43 377 4.7E-73 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 Gene3D G3DSA:2.30.40.10 1 66 2.8E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 SUPERFAMILY SSF51338 352 381 6.62E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS18250 8aedc4aaaa43a45516556331a5e2d4bb 383 SUPERFAMILY SSF51338 9 51 6.62E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 200.888 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 428 1.2E-163 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 Gene3D G3DSA:3.40.440.10 1 156 4.4E-51 T 28-03-2018 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 Gene3D G3DSA:3.40.440.10 157 265 3.6E-22 T 28-03-2018 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 Pfam PF00709 Adenylosuccinate synthetase 4 422 5.0E-174 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 SUPERFAMILY SSF52540 1 428 7.75E-169 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 SMART SM00788 3 423 4.0E-272 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CP478_RS01910 c397d82c3c0130c0a20322b5af109940 432 Gene3D G3DSA:3.90.170.10 266 430 1.7E-70 T 28-03-2018 CP478_RS14180 537ed5f103bc202508034a9bf94986b4 115 Pfam PF02699 Preprotein translocase subunit 6 81 1.4E-15 T 28-03-2018 IPR003849 Preprotein translocase YajC CP478_RS14180 537ed5f103bc202508034a9bf94986b4 115 SMART SM01323 2 84 1.0E-23 T 28-03-2018 IPR003849 Preprotein translocase YajC CP478_RS14180 537ed5f103bc202508034a9bf94986b4 115 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 1.1E-27 T 28-03-2018 IPR003849 Preprotein translocase YajC CP478_RS12030 042780ce487c812c570bc5391a143da4 592 Pfam PF00561 alpha/beta hydrolase fold 30 286 1.3E-35 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS12030 042780ce487c812c570bc5391a143da4 592 SUPERFAMILY SSF51735 326 561 2.53E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 474 493 5.6E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 400 411 5.6E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 448 464 5.6E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 326 343 5.6E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 512 5.6E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 Gene3D G3DSA:3.40.50.1820 4 299 2.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12030 042780ce487c812c570bc5391a143da4 592 Gene3D G3DSA:3.40.50.720 322 577 5.7E-61 T 28-03-2018 CP478_RS12030 042780ce487c812c570bc5391a143da4 592 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 461 489 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS12030 042780ce487c812c570bc5391a143da4 592 SUPERFAMILY SSF53474 8 298 1.95E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12030 042780ce487c812c570bc5391a143da4 592 Pfam PF00106 short chain dehydrogenase 327 514 2.5E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 400 411 4.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 454 462 4.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 474 493 4.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12030 042780ce487c812c570bc5391a143da4 592 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 325 510 0.0094 T 28-03-2018 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 SMART SM00563 56 175 8.9E-16 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 SUPERFAMILY SSF69593 211 265 5.23E-13 T 28-03-2018 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 SUPERFAMILY SSF69593 30 178 5.23E-13 T 28-03-2018 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 Gene3D G3DSA:3.40.1130.10 17 271 1.6E-13 T 28-03-2018 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 Pfam PF01553 Acyltransferase 43 171 1.8E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS07810 53849087996f4ddb4b8b6b3a47f3e406 275 PIRSF PIRSF016753 2 275 6.4E-92 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted CP478_RS02990 f5b98d4a82b890ee9698f7c9755c733b 112 Pfam PF05305 Protein of unknown function (DUF732) 9 103 9.9E-24 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 SUPERFAMILY SSF55021 6 77 2.75E-22 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 78 6.0E-39 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 Pfam PF13710 ACT domain 14 76 8.5E-19 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 SUPERFAMILY SSF55021 82 163 1.6E-25 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 Gene3D G3DSA:3.30.70.1150 91 163 6.5E-28 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 Gene3D G3DSA:3.30.70.260 1 90 1.1E-25 T 28-03-2018 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 5 161 8.8E-62 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CP478_RS16425 1d5e9eeb60f07bebb4c9c79c88f8a081 168 Pfam PF10369 Small subunit of acetolactate synthase 87 160 1.7E-26 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CP478_RS15600 f43556b7157b945cab951afa0590623d 346 SUPERFAMILY SSF53474 49 314 1.63E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15600 f43556b7157b945cab951afa0590623d 346 Pfam PF12146 Serine aminopeptidase, S33 51 201 2.3E-17 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CP478_RS15600 f43556b7157b945cab951afa0590623d 346 Gene3D G3DSA:3.40.50.1820 40 330 4.8E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02375 60c294f867e5df4d84a006809425fbe6 427 SUPERFAMILY SSF53335 152 423 2.3E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02375 60c294f867e5df4d84a006809425fbe6 427 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 419 2.2E-105 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02375 60c294f867e5df4d84a006809425fbe6 427 PIRSF PIRSF003085 22 427 7.5E-136 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS02375 60c294f867e5df4d84a006809425fbe6 427 Gene3D G3DSA:3.40.50.150 138 423 1.4E-60 T 28-03-2018 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 Gene3D G3DSA:3.30.450.20 23 295 6.1E-11 T 28-03-2018 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 Gene3D G3DSA:3.30.70.1230 542 730 5.0E-38 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 Pfam PF00672 HAMP domain 466 513 2.6E-15 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 SMART SM00044 521 712 4.6E-33 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 Gene3D G3DSA:3.30.450.20 296 444 6.4E-9 T 28-03-2018 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 SUPERFAMILY SSF55073 544 723 8.32E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 550 719 4.7E-35 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 SUPERFAMILY SSF158472 467 514 4.97E-11 T 28-03-2018 CP478_RS13300 f272851974e327ca71881dc2cdc05fa7 730 SMART SM00304 465 517 1.5E-16 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS09455 b2bd1a58454b052f9b65d884b2b1c065 80 Gene3D G3DSA:3.30.559.10 1 76 1.2E-9 T 28-03-2018 CP478_RS09455 b2bd1a58454b052f9b65d884b2b1c065 80 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 2 71 5.8E-9 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS09455 b2bd1a58454b052f9b65d884b2b1c065 80 SUPERFAMILY SSF52777 1 71 2.0E-11 T 28-03-2018 CP478_RS17030 786e474222906cbc70729c122ab690c5 83 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 4 83 2.3E-20 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CP478_RS17030 786e474222906cbc70729c122ab690c5 83 SUPERFAMILY SSF54285 1 81 9.16E-19 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CP478_RS17030 786e474222906cbc70729c122ab690c5 83 Gene3D G3DSA:3.10.20.30 4 83 1.7E-21 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS17030 786e474222906cbc70729c122ab690c5 83 Pfam PF02597 ThiS family 6 83 5.6E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Pfam PF00005 ABC transporter 627 774 2.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Pfam PF04954 Siderophore-interacting protein 131 241 6.3E-23 T 28-03-2018 IPR007037 Siderophore-interacting protein CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Gene3D G3DSA:3.40.50.80 122 262 1.0E-27 T 28-03-2018 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Gene3D G3DSA:1.20.1560.10 280 596 2.3E-35 T 28-03-2018 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 SUPERFAMILY SSF90123 284 591 7.98E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 SMART SM00382 635 820 6.6E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 ProSitePatterns PS00211 ABC transporters family signature. 746 760 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Gene3D G3DSA:3.40.50.300 597 850 2.0E-68 T 28-03-2018 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Pfam PF08021 Siderophore-interacting FAD-binding domain 61 113 2.1E-10 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Gene3D G3DSA:2.40.30.10 12 114 2.2E-22 T 28-03-2018 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 Pfam PF00664 ABC transporter transmembrane region 294 552 3.9E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 SUPERFAMILY SSF52540 607 843 2.45E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07390 4cc2793d034e5c62ad1ce801d7017de5 859 SUPERFAMILY SSF63380 14 117 4.73E-10 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 Gene3D G3DSA:3.40.47.10 211 353 1.5E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 10 196 6.8E-20 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 PIRSF PIRSF000451 1 353 4.6E-116 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 SUPERFAMILY SSF53901 3 352 9.61E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 Gene3D G3DSA:3.40.47.10 1 206 6.2E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09080 9c9f6bb06315f52f43be4586f45bf3d4 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 219 351 1.2E-16 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CP478_RS09440 a22b107172a4b5a43953b40b5e33c98f 518 Pfam PF00171 Aldehyde dehydrogenase family 29 481 8.5E-137 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS09440 a22b107172a4b5a43953b40b5e33c98f 518 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS09440 a22b107172a4b5a43953b40b5e33c98f 518 Gene3D G3DSA:3.40.309.10 272 466 4.7E-62 T 28-03-2018 CP478_RS09440 a22b107172a4b5a43953b40b5e33c98f 518 SUPERFAMILY SSF53720 32 482 6.68E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS09440 a22b107172a4b5a43953b40b5e33c98f 518 Gene3D G3DSA:3.40.605.10 11 271 6.5E-75 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS01640 13879967f468dd5b1c188476cda0fc52 223 SUPERFAMILY SSF55469 10 210 6.54E-47 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS01640 13879967f468dd5b1c188476cda0fc52 223 Pfam PF00881 Nitroreductase family 14 178 2.9E-24 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CP478_RS01640 13879967f468dd5b1c188476cda0fc52 223 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 2 202 2.1E-69 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CP478_RS01640 13879967f468dd5b1c188476cda0fc52 223 Gene3D G3DSA:3.40.109.10 1 205 2.9E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS07365 a67eb0d8e9d06d7b798af3904e1c4c19 106 Gene3D G3DSA:1.10.1200.10 18 106 1.5E-14 T 28-03-2018 CP478_RS07365 a67eb0d8e9d06d7b798af3904e1c4c19 106 SUPERFAMILY SSF47336 28 103 3.01E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS07365 a67eb0d8e9d06d7b798af3904e1c4c19 106 Pfam PF00550 Phosphopantetheine attachment site 33 99 3.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 Gene3D G3DSA:3.30.70.20 1 63 3.4E-6 T 28-03-2018 CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 Pfam PF13459 4Fe-4S single cluster domain 3 59 4.9E-14 T 28-03-2018 CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 SUPERFAMILY SSF54862 2 60 3.29E-10 T 28-03-2018 CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CP478_RS19155 a434bdaf42da3e4f8c26168f6e752d21 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CP478_RS17260 a81b0c6c0374c813f349ecb464f1f522 410 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 8 341 24.434 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17260 a81b0c6c0374c813f349ecb464f1f522 410 Pfam PF00146 NADH dehydrogenase 15 334 7.8E-123 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17260 a81b0c6c0374c813f349ecb464f1f522 410 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 54 69 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17260 a81b0c6c0374c813f349ecb464f1f522 410 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 218 231 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS11520 3af29ab3d647d5ceace83c5d9382413d 97 SUPERFAMILY SSF103007 1 96 8.37E-30 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CP478_RS11520 3af29ab3d647d5ceace83c5d9382413d 97 Gene3D G3DSA:3.30.70.1120 2 92 1.2E-32 T 28-03-2018 CP478_RS11520 3af29ab3d647d5ceace83c5d9382413d 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 7.9E-31 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 PIRSF PIRSF000355 3 319 5.3E-75 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 100 116 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 Gene3D G3DSA:1.10.620.20 4 294 3.8E-76 T 28-03-2018 CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 SUPERFAMILY SSF47240 9 322 4.53E-100 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 Pfam PF00268 Ribonucleotide reductase, small chain 12 283 1.2E-82 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS10780 9ece6a7a68cdf26300263ae8b7becd7a 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 10 322 3.7E-138 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS14400 b0501d9773b2bcbeda45363d9d6d5245 374 SUPERFAMILY SSF55315 253 364 8.24E-6 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS14400 b0501d9773b2bcbeda45363d9d6d5245 374 Gene3D G3DSA:3.30.420.60 117 243 1.7E-18 T 28-03-2018 CP478_RS14400 b0501d9773b2bcbeda45363d9d6d5245 374 Gene3D G3DSA:3.30.1330.30 249 364 3.9E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 Pfam PF00069 Protein kinase domain 21 265 8.5E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 SUPERFAMILY SSF56112 17 277 2.6E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 Gene3D G3DSA:1.10.510.10 102 332 5.8E-48 T 28-03-2018 CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 Gene3D G3DSA:3.30.200.20 7 101 3.3E-18 T 28-03-2018 CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 PIRSF PIRSF000654 30 282 3.8E-22 T 28-03-2018 CP478_RS11830 3341dd3b37ec80864f9516e43fd7e0c6 399 SMART SM00220 19 283 3.8E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 5.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 SUPERFAMILY SSF48498 112 174 7.42E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 Gene3D G3DSA:1.10.10.60 7 39 2.5E-13 T 28-03-2018 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 SUPERFAMILY SSF46689 9 78 5.08E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 Gene3D G3DSA:1.10.260.40 40 90 8.6E-4 T 28-03-2018 CP478_RS06675 fbec9b67749b3678f87d517608fd9c89 212 Gene3D G3DSA:1.10.357.10 91 180 2.6E-6 T 28-03-2018 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 PRINTS PR00834 HtrA/DegQ protease family signature 261 285 2.1E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 PRINTS PR00834 HtrA/DegQ protease family signature 407 419 2.1E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 2.1E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 PRINTS PR00834 HtrA/DegQ protease family signature 190 202 2.1E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 PRINTS PR00834 HtrA/DegQ protease family signature 302 319 2.1E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 Gene3D G3DSA:2.40.10.10 151 261 4.7E-30 T 28-03-2018 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 SMART SM00228 377 449 1.7E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 SUPERFAMILY SSF50156 376 461 6.44E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 Gene3D G3DSA:2.30.42.10 379 464 2.1E-16 T 28-03-2018 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 Gene3D G3DSA:2.40.10.10 262 378 1.4E-36 T 28-03-2018 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 Pfam PF13365 Trypsin-like peptidase domain 181 331 5.3E-35 T 28-03-2018 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 Pfam PF13180 PDZ domain 378 459 5.4E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS05370 d2563f5b5bbdba407a36f4906e2c99cb 464 SUPERFAMILY SSF50494 142 385 1.88E-54 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS20195 59cd1f35c17281b3c565a2ea552aa33c 145 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 141 16.197 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS20195 59cd1f35c17281b3c565a2ea552aa33c 145 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 144 3.7E-50 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS20195 59cd1f35c17281b3c565a2ea552aa33c 145 Gene3D G3DSA:3.40.50.1010 4 141 6.0E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS20195 59cd1f35c17281b3c565a2ea552aa33c 145 SUPERFAMILY SSF88723 5 142 6.87E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS20195 59cd1f35c17281b3c565a2ea552aa33c 145 Pfam PF01850 PIN domain 6 135 4.1E-7 T 28-03-2018 IPR002716 PIN domain CP478_RS03495 9e6aceab2d36f1505edbfee7a5dd425c 488 Pfam PF03109 ABC1 family 150 271 8.3E-36 T 28-03-2018 IPR004147 UbiB domain CP478_RS03495 9e6aceab2d36f1505edbfee7a5dd425c 488 Gene3D G3DSA:3.30.200.20 140 279 3.8E-25 T 28-03-2018 CP478_RS03495 9e6aceab2d36f1505edbfee7a5dd425c 488 Gene3D G3DSA:1.10.510.10 280 416 3.2E-4 T 28-03-2018 CP478_RS03495 9e6aceab2d36f1505edbfee7a5dd425c 488 SUPERFAMILY SSF56112 230 355 2.97E-29 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS03495 9e6aceab2d36f1505edbfee7a5dd425c 488 SUPERFAMILY SSF56112 134 196 2.97E-29 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PRINTS PR00960 LmbP protein signature 8 23 4.6E-53 T 28-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PRINTS PR00960 LmbP protein signature 149 168 4.6E-53 T 28-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PRINTS PR00960 LmbP protein signature 258 282 4.6E-53 T 28-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PRINTS PR00960 LmbP protein signature 286 305 4.6E-53 T 28-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PRINTS PR00960 LmbP protein signature 107 128 4.6E-53 T 28-03-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 SUPERFAMILY SSF55060 195 345 2.4E-23 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 PIRSF PIRSF036406 2 346 4.5E-152 T 28-03-2018 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 Gene3D G3DSA:3.30.70.890 196 331 2.0E-16 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 SUPERFAMILY SSF54211 4 188 1.21E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 Gene3D G3DSA:3.30.230.10 4 195 3.7E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 Pfam PF08544 GHMP kinases C terminal 243 323 4.8E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS00630 aa62647d5d89b084655cff60f113580a 386 Pfam PF00288 GHMP kinases N terminal domain 106 169 2.2E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CP478_RS17530 28f9351ffd5a7bea5256102b97ee9f84 84 SUPERFAMILY SSF52833 6 76 6.72E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS17530 28f9351ffd5a7bea5256102b97ee9f84 84 Gene3D G3DSA:3.40.30.10 1 84 6.5E-15 T 28-03-2018 CP478_RS17530 28f9351ffd5a7bea5256102b97ee9f84 84 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 6 79 3.3E-34 T 28-03-2018 IPR011915 Glutaredoxin-like protein, actinobacteria CP478_RS17530 28f9351ffd5a7bea5256102b97ee9f84 84 Pfam PF00462 Glutaredoxin 7 61 6.0E-12 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 PIRSF PIRSF001456 1 389 2.9E-126 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 SUPERFAMILY SSF103263 2 389 2.22E-134 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 Pfam PF01264 Chorismate synthase 2 367 6.1E-118 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 Hamap MF_00300 Chorismate synthase [aroC]. 2 374 34.291 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 Gene3D G3DSA:3.60.150.10 1 401 4.5E-145 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 ProSitePatterns PS00789 Chorismate synthase signature 3. 341 357 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS13920 9537608a95d21a296bc4599dc13a570c 401 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 2.9E-125 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CP478_RS17865 f464d1395e8ec60057a1bdfe643dba1f 139 Pfam PF06262 Zincin-like metallopeptidase 86 132 1.9E-6 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CP478_RS17865 f464d1395e8ec60057a1bdfe643dba1f 139 SUPERFAMILY SSF55486 13 135 5.49E-21 T 28-03-2018 CP478_RS17910 6d15fde56f6dd036adb3436248186d15 304 Gene3D G3DSA:3.40.50.720 3 204 1.3E-35 T 28-03-2018 CP478_RS17910 6d15fde56f6dd036adb3436248186d15 304 SUPERFAMILY SSF51735 7 286 4.0E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17910 6d15fde56f6dd036adb3436248186d15 304 Gene3D G3DSA:3.90.25.10 205 274 6.5E-17 T 28-03-2018 CP478_RS17910 6d15fde56f6dd036adb3436248186d15 304 Pfam PF04321 RmlD substrate binding domain 7 288 1.7E-108 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CP478_RS17910 6d15fde56f6dd036adb3436248186d15 304 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 7 287 1.7E-109 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CP478_RS03720 2781d5b6d66d96a5889cbfacd321fa51 84 Gene3D G3DSA:3.10.180.10 1 84 2.3E-4 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS09655 605b99542eba1af70811994a10140636 428 Gene3D G3DSA:3.40.462.10 176 391 1.2E-49 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CP478_RS09655 605b99542eba1af70811994a10140636 428 SUPERFAMILY SSF56176 4 178 4.44E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS09655 605b99542eba1af70811994a10140636 428 Pfam PF01565 FAD binding domain 16 151 2.8E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS09655 605b99542eba1af70811994a10140636 428 Gene3D G3DSA:3.30.43.10 2 64 1.1E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS09655 605b99542eba1af70811994a10140636 428 Pfam PF04030 D-arabinono-1,4-lactone oxidase 172 425 4.1E-85 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CP478_RS09655 605b99542eba1af70811994a10140636 428 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 16 49 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CP478_RS09655 605b99542eba1af70811994a10140636 428 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 5 427 6.0E-221 T 28-03-2018 CP478_RS09655 605b99542eba1af70811994a10140636 428 Gene3D G3DSA:1.10.45.10 392 426 6.9E-4 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS09655 605b99542eba1af70811994a10140636 428 Gene3D G3DSA:3.30.465.10 65 175 1.4E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS09655 605b99542eba1af70811994a10140636 428 PIRSF PIRSF000136 1 428 4.7E-159 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CP478_RS10825 18230216def53b60b568ae1b03316a5f 179 SUPERFAMILY SSF53335 7 172 3.01E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10825 18230216def53b60b568ae1b03316a5f 179 SMART SM00650 20 172 2.0E-49 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CP478_RS10825 18230216def53b60b568ae1b03316a5f 179 Gene3D G3DSA:3.40.50.150 5 174 3.1E-26 T 28-03-2018 CP478_RS10825 18230216def53b60b568ae1b03316a5f 179 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 172 4.1E-19 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 Gene3D G3DSA:3.40.50.970 22 215 1.1E-56 T 28-03-2018 CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 SUPERFAMILY SSF52518 26 204 1.82E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 Pfam PF02780 Transketolase, C-terminal domain 215 336 8.1E-35 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 SMART SM00861 26 201 5.0E-63 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 SUPERFAMILY SSF52922 213 345 1.83E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 Pfam PF02779 Transketolase, pyrimidine binding domain 25 199 4.0E-40 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS13650 8f9c9a22f58100bc2d0511aacbdf03c0 348 Gene3D G3DSA:3.40.50.920 216 346 6.4E-28 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 2.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 SUPERFAMILY SSF51735 6 274 2.19E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 3.2E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 8 273 1.7E-108 T 28-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 271 5.9E-49 T 28-03-2018 CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 Gene3D G3DSA:3.40.50.720 3 274 5.7E-69 T 28-03-2018 CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 195 0.0031 T 28-03-2018 CP478_RS03710 37e482646e0753920c3b1dd9e6d26bd4 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 Gene3D G3DSA:3.30.70.20 45 104 8.8E-9 T 28-03-2018 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 SUPERFAMILY SSF54862 4 83 1.13E-19 T 28-03-2018 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 Gene3D G3DSA:3.30.70.20 2 44 1.1E-10 T 28-03-2018 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.7E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.7E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS06460 7bb92f2e7a2390ce7520ccfb46e63c6e 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.7E-18 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS08365 731ed82216eb338329f333054728bb0c 261 Gene3D G3DSA:3.90.550.10 3 252 9.2E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08365 731ed82216eb338329f333054728bb0c 261 SUPERFAMILY SSF53448 10 215 2.72E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08100 f37dd6ed6fe3bd2928b1215567233688 241 Pfam PF00877 NlpC/P60 family 124 238 5.8E-31 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CP478_RS08100 f37dd6ed6fe3bd2928b1215567233688 241 Gene3D G3DSA:3.90.1720.10 105 241 3.8E-36 T 28-03-2018 CP478_RS08100 f37dd6ed6fe3bd2928b1215567233688 241 SUPERFAMILY SSF54001 108 232 3.04E-33 T 28-03-2018 CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 Gene3D G3DSA:2.140.10.10 30 161 9.0E-6 T 28-03-2018 CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 SUPERFAMILY SSF50998 33 123 7.85E-15 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 SUPERFAMILY SSF50998 196 358 7.85E-15 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 Pfam PF13360 PQQ-like domain 189 340 9.1E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 Gene3D G3DSA:2.140.10.10 162 297 1.4E-10 T 28-03-2018 CP478_RS16605 1e6e59f9157404148c7865b9a1ef30ad 360 Gene3D G3DSA:2.140.10.10 298 360 9.1E-4 T 28-03-2018 CP478_RS10770 1a72391e5a352085a254e3acdb770bb1 481 PIRSF PIRSF006060 4 481 6.2E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS10770 1a72391e5a352085a254e3acdb770bb1 481 Pfam PF13520 Amino acid permease 14 457 1.4E-38 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 50 366 2.4E-148 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 Pfam PF01063 Amino-transferase class IV 76 323 1.2E-32 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 Gene3D G3DSA:3.30.470.10 2 187 1.9E-64 T 28-03-2018 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 Gene3D G3DSA:3.20.10.10 188 350 1.2E-52 T 28-03-2018 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 ProSitePatterns PS00770 Aminotransferases class-IV signature. 240 273 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 SUPERFAMILY SSF56752 4 364 3.14E-112 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CP478_RS12010 54c78a0056cfc881392b20daa239c47d 368 PIRSF PIRSF006468 6 368 4.5E-131 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CP478_RS07970 5b075d91cac99d775cbe7f2d96e7522b 421 Gene3D G3DSA:1.10.10.60 315 378 4.6E-5 T 28-03-2018 CP478_RS07970 5b075d91cac99d775cbe7f2d96e7522b 421 Pfam PF13556 PucR C-terminal helix-turn-helix domain 344 395 3.0E-11 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 1 128 1.5E-50 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 135 176 1.2E-9 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 SMART SM00861 212 375 9.2E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 SUPERFAMILY SSF52922 397 518 3.01E-18 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Gene3D G3DSA:3.40.50.920 385 519 5.9E-21 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 SUPERFAMILY SSF52518 3 274 1.09E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Pfam PF02779 Transketolase, pyrimidine binding domain 212 372 1.0E-35 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Gene3D G3DSA:3.40.50.970 192 382 4.9E-44 T 28-03-2018 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Gene3D G3DSA:3.40.50.970 1 191 6.0E-50 T 28-03-2018 CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 Pfam PF02780 Transketolase, C-terminal domain 396 509 3.6E-23 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CP478_RS18505 65edcfeb703da87ee4b956e15d5350f4 536 ProSitePatterns PS00802 Transketolase signature 2. 318 334 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 SUPERFAMILY SSF55486 4 147 1.37E-39 T 28-03-2018 CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 6.7E-33 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 Gene3D G3DSA:3.40.390.30 2 166 1.7E-43 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 158 21.234 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CP478_RS12910 6abfa3f0f17b1c4b0e82bf3171de0857 177 Pfam PF02130 Uncharacterized protein family UPF0054 20 147 9.4E-37 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 SUPERFAMILY SSF52518 291 476 1.25E-54 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 1 621 41.275 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 SUPERFAMILY SSF52922 501 619 5.5E-22 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 SMART SM00861 314 478 2.2E-54 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Gene3D G3DSA:3.40.50.970 1 306 3.1E-75 T 28-03-2018 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 2 278 1.5E-106 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 ProSitePatterns PS00801 Transketolase signature 1. 27 46 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Pfam PF02780 Transketolase, C-terminal domain 500 612 3.5E-26 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 SUPERFAMILY SSF52518 18 193 3.93E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 SUPERFAMILY SSF52518 238 361 3.93E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 620 3.5E-188 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Gene3D G3DSA:3.40.50.970 307 478 3.7E-38 T 28-03-2018 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Gene3D G3DSA:3.40.50.920 487 626 2.9E-27 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS14705 5b6dfcbde7a2fb76974ed5edd55bedf8 638 Pfam PF02779 Transketolase, pyrimidine binding domain 315 476 1.0E-37 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS10860 4a1918113e9ce71dabda477c98d54af0 82 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 38 4.4E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS10860 4a1918113e9ce71dabda477c98d54af0 82 SUPERFAMILY SSF47598 3 39 1.59E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS10860 4a1918113e9ce71dabda477c98d54af0 82 Gene3D G3DSA:1.10.1220.10 1 40 1.1E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS00930 89f0c0a20f4a3f8543433bb4e57f0782 454 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 454 1.7E-109 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS00930 89f0c0a20f4a3f8543433bb4e57f0782 454 Pfam PF02470 MlaD protein 45 124 1.1E-13 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS00930 89f0c0a20f4a3f8543433bb4e57f0782 454 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 305 8.3E-87 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS09810 5c9eceec7684640b0a9dfb54690c5be9 423 Gene3D G3DSA:1.10.287.1060 21 104 8.9E-6 T 28-03-2018 CP478_RS09810 5c9eceec7684640b0a9dfb54690c5be9 423 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 318 388 3.5E-8 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09810 5c9eceec7684640b0a9dfb54690c5be9 423 SUPERFAMILY SSF140459 2 173 8.63E-67 T 28-03-2018 CP478_RS09810 5c9eceec7684640b0a9dfb54690c5be9 423 Pfam PF00823 PPE family 6 160 3.7E-64 T 28-03-2018 IPR000030 PPE family CP478_RS20005 49d1831eb482cbb0b901cfa1836961b1 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 261 4.1E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20005 49d1831eb482cbb0b901cfa1836961b1 266 SUPERFAMILY SSF161098 55 245 1.11E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20005 49d1831eb482cbb0b901cfa1836961b1 266 Gene3D G3DSA:1.10.3720.10 1 263 7.3E-38 T 28-03-2018 CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 Gene3D G3DSA:1.10.510.10 82 466 3.6E-41 T 28-03-2018 CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 Pfam PF00069 Protein kinase domain 13 226 9.6E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 SUPERFAMILY SSF56112 11 367 2.83E-63 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 SMART SM00220 12 274 4.5E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS09525 177cd6b8d1392baca6174858ce2a45ab 476 Gene3D G3DSA:3.30.200.20 9 81 8.9E-15 T 28-03-2018 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 Pfam PF00425 chorismate binding enzyme 234 492 8.0E-93 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 PRINTS PR00095 Anthranilate synthase component I signature 340 353 3.7E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 PRINTS PR00095 Anthranilate synthase component I signature 434 448 3.7E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 PRINTS PR00095 Anthranilate synthase component I signature 354 367 3.7E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 PRINTS PR00095 Anthranilate synthase component I signature 449 463 3.7E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 SUPERFAMILY SSF56322 22 500 3.01E-149 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 Gene3D G3DSA:3.60.120.10 22 504 1.2E-158 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 32 500 9.6E-163 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS08800 182c0158542d45a029e51cb727b3c26e 516 Pfam PF04715 Anthranilate synthase component I, N terminal region 33 177 6.2E-32 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.40.366.10 630 761 1.7E-33 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.40.47.10 366 527 3.7E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF47336 1761 1843 2.09E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 264 280 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF55048 754 817 3.4E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1491 1685 2.0E-47 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.30.70.250 762 811 2.4E-15 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.40.50.720 1483 1761 4.3E-37 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF51735 1287 1476 6.69E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 102 351 2.2E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00826 991 1150 3.9E-5 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:1.10.1200.10 4 82 7.4E-13 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM01294 1766 1832 1.3E-6 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF00698 Acyl transferase domain 632 949 3.1E-118 T 28-03-2018 IPR014043 Acyl transferase CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 359 477 8.0E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF00550 Phosphopantetheine attachment site 14 79 1.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF00550 Phosphopantetheine attachment site 1767 1832 8.1E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 634 932 9.8E-83 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:1.10.1200.10 1762 1838 6.3E-21 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.40.366.10 812 938 4.1E-17 T 28-03-2018 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF51735 1489 1718 6.88E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF53901 504 525 2.08E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF53901 100 472 2.08E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF14765 Polyketide synthase dehydratase 1003 1261 1.9E-16 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00823 Phosphopantetheine attachment site 1765 1836 3.3E-20 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00823 Phosphopantetheine attachment site 12 83 4.0E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 480 584 4.3E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF52151 631 756 3.14E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF52151 819 916 3.14E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Pfam PF08659 KR domain 1491 1683 3.0E-61 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SMART SM00825 Beta-ketoacyl synthase 104 529 1.1E-221 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1791 1806 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 Gene3D G3DSA:3.40.47.10 94 363 2.8E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS16015 a1640fbd1bcbf1865a182382133e4aac 1876 SUPERFAMILY SSF47336 10 117 7.72E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS21115 5b47800d48830175135450c2cdd299da 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 89 13.109 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS21115 5b47800d48830175135450c2cdd299da 116 Pfam PF02467 Transcription factor WhiB 36 82 2.2E-7 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 9 289 22.316 T 28-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 SUPERFAMILY SSF51604 77 288 5.9E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 Gene3D G3DSA:3.20.20.120 97 292 1.5E-32 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 Gene3D G3DSA:3.30.390.10 14 96 8.9E-39 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 SMART SM00922 87 184 4.8E-17 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CP478_RS02960 f6ce8a906f225ce08c26511917fa59b6 326 Pfam PF13378 Enolase C-terminal domain-like 103 287 1.4E-30 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS02090 0cdaa8cc4c40b80ee575d5ca6af5d3d4 441 Gene3D G3DSA:3.40.50.2000 70 131 0.0022 T 28-03-2018 CP478_RS02090 0cdaa8cc4c40b80ee575d5ca6af5d3d4 441 Pfam PF02720 Domain of unknown function (DUF222) 100 281 6.0E-45 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS02090 0cdaa8cc4c40b80ee575d5ca6af5d3d4 441 Gene3D G3DSA:3.40.1800.10 266 333 2.3E-4 T 28-03-2018 CP478_RS02090 0cdaa8cc4c40b80ee575d5ca6af5d3d4 441 SMART SM00507 272 324 6.1E-9 T 28-03-2018 IPR003615 HNH nuclease CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 268 279 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 286 313 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 132 148 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 149 164 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 345 356 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 314 329 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 PRINTS PR00359 B-class P450 signature 336 345 4.9E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 Gene3D G3DSA:1.10.630.10 1 396 4.6E-42 T 28-03-2018 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 Pfam PF00067 Cytochrome P450 217 364 1.8E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS12375 672140e8a5b6f0e7cc6bdbd648f3574c 396 SUPERFAMILY SSF48264 17 396 1.57E-62 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 1.7E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 1.7E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.7E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.7E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 SUPERFAMILY SSF56655 3 258 1.28E-71 T 28-03-2018 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 Gene3D G3DSA:3.30.540.10 2 147 6.7E-42 T 28-03-2018 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 6 257 4.7E-84 T 28-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 Gene3D G3DSA:3.40.190.80 148 260 3.1E-23 T 28-03-2018 CP478_RS17185 c0d24782220d6767c9286d56486f89df 260 Pfam PF00459 Inositol monophosphatase family 9 251 7.4E-45 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 SUPERFAMILY SSF53474 25 285 5.63E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 Pfam PF12697 Alpha/beta hydrolase family 36 281 1.4E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 Gene3D G3DSA:3.40.50.1820 13 287 1.1E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 PRINTS PR00412 Epoxide hydrolase signature 263 285 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 PRINTS PR00412 Epoxide hydrolase signature 39 57 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09975 b043d000e9b68124c99390b5c1e819a9 288 PRINTS PR00412 Epoxide hydrolase signature 102 115 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12965 cafb70960f0d3f17d4d5b8bf26001769 431 SUPERFAMILY SSF51905 3 240 1.97E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12965 cafb70960f0d3f17d4d5b8bf26001769 431 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 88 284 1.2E-11 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CP478_RS12965 cafb70960f0d3f17d4d5b8bf26001769 431 Gene3D G3DSA:3.50.50.60 198 405 5.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12965 cafb70960f0d3f17d4d5b8bf26001769 431 Gene3D G3DSA:3.50.50.60 1 180 4.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 SUPERFAMILY SSF51735 113 270 1.95E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 Gene3D G3DSA:3.90.180.10 1 133 1.0E-36 T 28-03-2018 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 Gene3D G3DSA:3.40.50.720 134 312 1.4E-40 T 28-03-2018 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 SMART SM00829 10 326 3.1E-44 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 5 328 8.1E-140 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.0E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 Pfam PF00107 Zinc-binding dehydrogenase 151 266 2.3E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS20640 e161a5225bcfea6ea46bdade397a2681 328 SUPERFAMILY SSF50129 4 141 7.39E-37 T 28-03-2018 IPR011032 GroES-like CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 Pfam PF00162 Phosphoglycerate kinase 14 394 1.8E-132 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 SUPERFAMILY SSF53748 9 403 6.01E-134 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 Gene3D G3DSA:3.40.50.1260 4 189 1.9E-54 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 Gene3D G3DSA:3.40.50.1260 190 392 1.3E-73 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 404 38.419 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PIRSF PIRSF000724 1 408 1.8E-124 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 178 200 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 148 170 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 35 57 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 356 367 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 320 345 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 380 397 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07860 7fe635f0f78ffeb1c7264c605d65bd3a 412 PRINTS PR00477 Phosphoglycerate kinase family signature 201 220 4.8E-73 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 Pfam PF00083 Sugar (and other) transporter 28 219 1.1E-24 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 Pfam PF00083 Sugar (and other) transporter 223 435 1.4E-13 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 321 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 Gene3D G3DSA:1.20.1250.20 228 443 1.9E-23 T 28-03-2018 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 Gene3D G3DSA:1.20.1250.20 19 227 3.5E-24 T 28-03-2018 CP478_RS19015 cf19f50b91e051a4e9244757d98880ba 449 SUPERFAMILY SSF103473 8 434 2.09E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12795 184a8da4e0aed7f7c92cbb2d5dd4847e 660 Gene3D G3DSA:1.20.5.50 221 346 0.33 T 28-03-2018 CP478_RS12795 184a8da4e0aed7f7c92cbb2d5dd4847e 660 Gene3D G3DSA:1.20.5.50 472 573 0.054 T 28-03-2018 CP478_RS12795 184a8da4e0aed7f7c92cbb2d5dd4847e 660 Gene3D G3DSA:1.20.1480.30 347 455 0.0061 T 28-03-2018 CP478_RS12795 184a8da4e0aed7f7c92cbb2d5dd4847e 660 Pfam PF04536 TPM domain 36 153 3.5E-17 T 28-03-2018 IPR007621 TPM domain CP478_RS07690 a2ddc9b61910f9f4f566f296b60e4329 160 Pfam PF01047 MarR family 43 100 2.6E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS07690 a2ddc9b61910f9f4f566f296b60e4329 160 SUPERFAMILY SSF46785 17 149 3.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07690 a2ddc9b61910f9f4f566f296b60e4329 160 SMART SM00347 36 136 9.3E-30 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS07690 a2ddc9b61910f9f4f566f296b60e4329 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 74 109 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CP478_RS07690 a2ddc9b61910f9f4f566f296b60e4329 160 Gene3D G3DSA:1.10.10.10 2 151 2.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 ProSitePatterns PS00517 Ribonuclease III family signature. 41 49 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 SMART SM00535 19 155 7.2E-55 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 SUPERFAMILY SSF54768 116 232 3.93E-28 T 28-03-2018 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 Gene3D G3DSA:1.10.1520.10 16 156 1.3E-38 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 17 227 1.0E-70 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 Pfam PF14622 Ribonuclease-III-like 18 144 1.4E-35 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 SMART SM00358 162 228 9.5E-25 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 Gene3D G3DSA:3.30.160.20 160 229 5.2E-21 T 28-03-2018 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 224 28.98 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 Pfam PF00035 Double-stranded RNA binding motif 162 227 1.2E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CP478_RS15985 92399ae7e74c5672f4516c768714ec5a 240 SUPERFAMILY SSF69065 8 163 5.41E-43 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 78 18.064 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 75 7.9E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 8.5E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 8.5E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 8.5E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 8.5E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 Gene3D G3DSA:4.10.640.10 1 82 1.1E-26 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 Pfam PF01084 Ribosomal protein S18 24 73 5.2E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 SUPERFAMILY SSF46911 5 78 3.66E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 26 75 2.0E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11205 3f9457a3395bf0e42fea250d45069a25 88 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 SUPERFAMILY SSF109709 147 256 1.16E-31 T 28-03-2018 CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 SMART SM00470 61 155 1.3E-37 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 SUPERFAMILY SSF110849 54 158 8.37E-30 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 Pfam PF02195 ParB-like nuclease domain 62 155 6.0E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 Gene3D G3DSA:3.90.1530.10 51 155 3.0E-36 T 28-03-2018 CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 Gene3D G3DSA:1.10.10.730 156 203 2.4E-17 T 28-03-2018 CP478_RS21405 feeb1d1e0d879924752d4b025ec81f18 344 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 60 241 5.0E-65 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CP478_RS14805 18126ee56b1a1f619bd554b27b3e779a 216 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 90 179 4.6E-14 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 248 261 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 SUPERFAMILY SSF51735 2 136 1.37E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 PIRSF PIRSF001553 1 303 1.2E-120 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 Pfam PF00549 CoA-ligase 181 283 2.5E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 166 193 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 Gene3D G3DSA:3.40.50.720 2 133 1.8E-39 T 28-03-2018 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 6 300 6.1E-134 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 SMART SM00881 7 112 1.7E-28 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 Gene3D G3DSA:3.40.50.261 134 303 1.2E-47 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 Pfam PF02629 CoA binding domain 10 111 2.8E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 4 300 38.86 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 PRINTS PR01798 Succinyl-CoA synthase signature 94 111 9.1E-35 T 28-03-2018 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 PRINTS PR01798 Succinyl-CoA synthase signature 189 207 9.1E-35 T 28-03-2018 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 PRINTS PR01798 Succinyl-CoA synthase signature 220 233 9.1E-35 T 28-03-2018 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 PRINTS PR01798 Succinyl-CoA synthase signature 252 269 9.1E-35 T 28-03-2018 CP478_RS05195 9dbb06c2db94d1fea2588207968faeb7 303 SUPERFAMILY SSF52210 137 297 1.44E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CP478_RS14950 6226864bd5c021a82e8cebd44c0b2ad1 301 SUPERFAMILY SSF103481 46 125 1.96E-5 T 28-03-2018 CP478_RS15075 1571c3816a6f0f4dd7772d889ae0025f 296 Gene3D G3DSA:3.40.50.150 7 283 3.3E-37 T 28-03-2018 CP478_RS15075 1571c3816a6f0f4dd7772d889ae0025f 296 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 270 8.2E-78 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS15075 1571c3816a6f0f4dd7772d889ae0025f 296 Pfam PF04072 Leucine carboxyl methyltransferase 11 193 2.7E-41 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS15075 1571c3816a6f0f4dd7772d889ae0025f 296 SUPERFAMILY SSF53335 8 278 5.82E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01195 6e306b4a3817dc090d01c5df35b51f26 469 Gene3D G3DSA:3.30.559.10 2 199 6.6E-5 T 28-03-2018 CP478_RS01195 6e306b4a3817dc090d01c5df35b51f26 469 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 453 4.6E-139 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS01195 6e306b4a3817dc090d01c5df35b51f26 469 SUPERFAMILY SSF52777 32 172 8.89E-9 T 28-03-2018 CP478_RS01195 6e306b4a3817dc090d01c5df35b51f26 469 Pfam PF06974 Protein of unknown function (DUF1298) 302 449 2.0E-32 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS01195 6e306b4a3817dc090d01c5df35b51f26 469 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 263 5.4E-85 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS02250 18d109f378130d4acca296ff73ffc5ea 265 SUPERFAMILY SSF53613 1 262 4.52E-74 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS02250 18d109f378130d4acca296ff73ffc5ea 265 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 2.1E-87 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CP478_RS02250 18d109f378130d4acca296ff73ffc5ea 265 Gene3D G3DSA:3.40.1190.20 1 265 1.5E-60 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS02250 18d109f378130d4acca296ff73ffc5ea 265 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 259 3.7E-84 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CP478_RS13390 73f2bfb28fcc66b9636fa7f7a4210b74 172 Pfam PF06737 Transglycosylase-like domain 96 168 3.2E-34 T 28-03-2018 IPR010618 Transglycosylase-like CP478_RS13390 73f2bfb28fcc66b9636fa7f7a4210b74 172 Gene3D G3DSA:1.10.530.10 30 172 9.7E-31 T 28-03-2018 CP478_RS13390 73f2bfb28fcc66b9636fa7f7a4210b74 172 SUPERFAMILY SSF53955 95 171 4.44E-31 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS19480 b45d92fd4b4dc3031182fd093e3bdc11 388 Pfam PF00155 Aminotransferase class I and II 32 381 2.7E-55 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS19480 b45d92fd4b4dc3031182fd093e3bdc11 388 SUPERFAMILY SSF53383 9 385 7.76E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS19480 b45d92fd4b4dc3031182fd093e3bdc11 388 Gene3D G3DSA:3.90.1150.10 274 387 1.2E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS19480 b45d92fd4b4dc3031182fd093e3bdc11 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CP478_RS19480 b45d92fd4b4dc3031182fd093e3bdc11 388 Gene3D G3DSA:3.40.640.10 40 273 1.4E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 SUPERFAMILY SSF55874 303 443 4.58E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 Gene3D G3DSA:3.30.565.10 297 445 5.4E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 SMART SM00388 230 296 2.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 443 3.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 293 6.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 SUPERFAMILY SSF47384 215 292 1.71E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 Gene3D G3DSA:1.10.287.130 213 292 1.7E-9 T 28-03-2018 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 Gene3D G3DSA:1.20.5.1040 12 65 0.0015 T 28-03-2018 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 SMART SM00304 170 222 3.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 SMART SM00387 338 446 5.0E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS04920 0eab6d5deac212fa269ac28461bbd4e6 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 1.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS06205 eb2bc9e5ff3fe2d0e5d44c64a6aa9ce2 78 Gene3D G3DSA:3.30.70.1060 1 54 9.5E-6 T 28-03-2018 CP478_RS07350 6b12f8dce7a4a32a83cbc3a5144d5486 204 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 6 197 5.5E-44 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CP478_RS07350 6b12f8dce7a4a32a83cbc3a5144d5486 204 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 200 46.258 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CP478_RS07350 6b12f8dce7a4a32a83cbc3a5144d5486 204 Pfam PF01725 Ham1 family 7 195 2.8E-52 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CP478_RS07350 6b12f8dce7a4a32a83cbc3a5144d5486 204 SUPERFAMILY SSF52972 4 199 3.66E-60 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CP478_RS07350 6b12f8dce7a4a32a83cbc3a5144d5486 204 Gene3D G3DSA:3.90.950.10 2 203 1.4E-71 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Gene3D G3DSA:1.10.540.10 1 121 1.9E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 204 1.5E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 SUPERFAMILY SSF56645 5 244 4.58E-62 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 1.1E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 SUPERFAMILY SSF47203 231 386 3.38E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 379 1.1E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Gene3D G3DSA:1.20.140.10 224 388 7.2E-37 T 28-03-2018 CP478_RS05305 70dbc0d6c0b8399b968f838d95d7f7cb 388 Gene3D G3DSA:2.40.110.10 123 223 1.4E-26 T 28-03-2018 CP478_RS08195 049af4b6e78e0fd04ee1772ab44b44cc 105 Gene3D G3DSA:2.30.30.110 2 103 1.7E-15 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS08195 049af4b6e78e0fd04ee1772ab44b44cc 105 SUPERFAMILY SSF50118 5 102 8.94E-20 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS08195 049af4b6e78e0fd04ee1772ab44b44cc 105 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 6 99 3.1E-14 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 PRINTS PR01438 Universal stress protein signature 119 141 3.2E-5 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 PRINTS PR01438 Universal stress protein signature 101 113 3.2E-5 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 Gene3D G3DSA:3.40.50.620 151 292 1.8E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 Gene3D G3DSA:3.40.50.620 2 145 7.9E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 Pfam PF00582 Universal stress protein family 161 291 2.3E-9 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 Pfam PF00582 Universal stress protein family 3 141 2.0E-18 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 SUPERFAMILY SSF52402 157 291 4.02E-15 T 28-03-2018 CP478_RS12645 b6264efdb5bf822c7b677845ac8182b4 292 SUPERFAMILY SSF52402 2 144 1.76E-20 T 28-03-2018 CP478_RS04670 556db943ad45c70a15c72a0d5b390519 359 Pfam PF02515 CoA-transferase family III 7 349 8.3E-75 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CP478_RS04670 556db943ad45c70a15c72a0d5b390519 359 Gene3D G3DSA:3.40.50.10540 1 357 2.1E-100 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS04670 556db943ad45c70a15c72a0d5b390519 359 SUPERFAMILY SSF89796 5 350 1.12E-100 T 28-03-2018 IPR023606 CoA-transferase family III domain CP478_RS12225 141f3a59a8d7a9d13a792c78ab757cb3 473 SUPERFAMILY SSF52096 15 211 8.25E-46 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS12225 141f3a59a8d7a9d13a792c78ab757cb3 473 Gene3D G3DSA:3.90.226.10 221 468 5.0E-62 T 28-03-2018 CP478_RS12225 141f3a59a8d7a9d13a792c78ab757cb3 473 SUPERFAMILY SSF52096 184 458 4.39E-70 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS12225 141f3a59a8d7a9d13a792c78ab757cb3 473 Gene3D G3DSA:3.90.226.10 5 220 9.5E-40 T 28-03-2018 CP478_RS12225 141f3a59a8d7a9d13a792c78ab757cb3 473 Pfam PF01039 Carboxyl transferase domain 38 459 1.0E-123 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 387 1.5E-146 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 Gene3D G3DSA:3.40.640.10 13 258 2.4E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 PIRSF PIRSF001434 1 388 5.0E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 SUPERFAMILY SSF53383 17 387 5.44E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS05915 b6fb4d8d7b7f7d4820c365ffa177c087 388 Gene3D G3DSA:3.90.1150.10 260 388 1.4E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS14715 30313f152b52006d5236b12fa2b807f8 165 SUPERFAMILY SSF54631 22 160 1.82E-14 T 28-03-2018 CP478_RS14715 30313f152b52006d5236b12fa2b807f8 165 Pfam PF00571 CBS domain 116 162 1.4E-4 T 28-03-2018 IPR000644 CBS domain CP478_RS14715 30313f152b52006d5236b12fa2b807f8 165 Gene3D G3DSA:3.10.580.10 14 165 2.3E-15 T 28-03-2018 CP478_RS14715 30313f152b52006d5236b12fa2b807f8 165 SMART SM00116 27 75 11.0 T 28-03-2018 IPR000644 CBS domain CP478_RS14715 30313f152b52006d5236b12fa2b807f8 165 SMART SM00116 116 163 0.13 T 28-03-2018 IPR000644 CBS domain CP478_RS01025 e281c9e6f76de6d45608b39e070ca520 220 Gene3D G3DSA:3.40.50.150 3 220 2.9E-37 T 28-03-2018 CP478_RS01025 e281c9e6f76de6d45608b39e070ca520 220 SUPERFAMILY SSF53335 4 216 2.19E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01025 e281c9e6f76de6d45608b39e070ca520 220 Pfam PF01596 O-methyltransferase 37 189 3.7E-33 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Pfam PF01769 Divalent cation transporter 326 448 2.1E-25 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Pfam PF03448 MgtE intracellular N domain 37 134 1.8E-17 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Gene3D G3DSA:3.10.580.10 126 273 2.0E-17 T 28-03-2018 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SUPERFAMILY SSF54631 136 275 1.64E-23 T 28-03-2018 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Gene3D G3DSA:1.25.60.10 32 125 3.2E-12 T 28-03-2018 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Pfam PF00571 CBS domain 204 251 8.2E-4 T 28-03-2018 IPR000644 CBS domain CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SUPERFAMILY SSF161093 283 454 6.8E-45 T 28-03-2018 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 TIGRFAM TIGR00400 mgtE: magnesium transporter 38 454 4.2E-88 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SMART SM00116 143 200 13.0 T 28-03-2018 IPR000644 CBS domain CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SMART SM00116 211 259 0.005 T 28-03-2018 IPR000644 CBS domain CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SMART SM00924 33 136 6.7E-19 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 Gene3D G3DSA:1.10.357.20 282 457 1.5E-39 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CP478_RS01935 c46a4ae2612dcfeffe119c6944d01a90 460 SUPERFAMILY SSF158791 37 133 1.7E-15 T 28-03-2018 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 Pfam PF00557 Metallopeptidase family M24 142 344 1.4E-60 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 314 326 1.6E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 207 1.6E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 216 232 1.6E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 PRINTS PR00599 Methionine aminopeptidase-1 signature 283 295 1.6E-7 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 SUPERFAMILY SSF55920 134 372 1.83E-69 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 292 304 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 Gene3D G3DSA:3.90.230.10 121 372 7.5E-73 T 28-03-2018 CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 SUPERFAMILY SSF53092 5 132 2.96E-24 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 Gene3D G3DSA:3.40.350.10 1 120 4.3E-30 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CP478_RS13895 8ba2ff0c49224139faf321fd0ad86075 372 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 134 1.3E-23 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CP478_RS07930 2c7340cc373db127e8720f2ada3004b2 303 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 294 5.8E-76 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CP478_RS07930 2c7340cc373db127e8720f2ada3004b2 303 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 302 2.1E-130 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CP478_RS09215 9d155c7e8c73a2645859b3aff5354b16 203 Gene3D G3DSA:3.10.300.10 1 196 2.1E-55 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CP478_RS09215 9d155c7e8c73a2645859b3aff5354b16 203 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 188 29.394 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CP478_RS09215 9d155c7e8c73a2645859b3aff5354b16 203 SUPERFAMILY SSF50486 2 195 4.32E-55 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CP478_RS09215 9d155c7e8c73a2645859b3aff5354b16 203 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 1 188 1.8E-74 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CP478_RS09215 9d155c7e8c73a2645859b3aff5354b16 203 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 9 185 2.2E-54 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 Gene3D G3DSA:3.30.1320.10 2 84 4.5E-29 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 3.3E-30 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.277 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 Pfam PF00886 Ribosomal protein S16 9 67 3.4E-22 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15890 eb74cc3575d0a367761d641a29b518d3 162 SUPERFAMILY SSF54565 2 94 9.29E-32 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 417 3.2E-120 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 PIRSF PIRSF000505 1 429 1.7E-127 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 425 28.649 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 16 423 1.9E-102 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 Gene3D G3DSA:3.65.10.10 230 424 1.0E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 Gene3D G3DSA:3.65.10.10 23 229 9.0E-57 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 SUPERFAMILY SSF55205 10 421 1.8E-93 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CP478_RS17705 625c674d6efe8cc91c6b9307318ce9ac 450 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CP478_RS08055 a2b9924f3f8b1bb089c8e3d4cda210a0 124 SUPERFAMILY SSF52833 5 103 7.14E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS08055 a2b9924f3f8b1bb089c8e3d4cda210a0 124 Gene3D G3DSA:3.40.30.10 2 113 7.0E-21 T 28-03-2018 CP478_RS08055 a2b9924f3f8b1bb089c8e3d4cda210a0 124 Pfam PF00085 Thioredoxin 5 95 6.6E-18 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CP478_RS20400 90bf49834763aa14de57c3c6f9d64876 454 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 451 8.6E-149 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS20400 90bf49834763aa14de57c3c6f9d64876 454 Gene3D G3DSA:3.30.559.10 37 180 4.4E-7 T 28-03-2018 CP478_RS20400 90bf49834763aa14de57c3c6f9d64876 454 SUPERFAMILY SSF52777 54 161 2.45E-8 T 28-03-2018 CP478_RS20400 90bf49834763aa14de57c3c6f9d64876 454 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 262 1.7E-99 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS20400 90bf49834763aa14de57c3c6f9d64876 454 Pfam PF06974 Protein of unknown function (DUF1298) 303 448 3.5E-34 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS14785 f30ff453f003b562dae0ac86c21cd240 259 Pfam PF12502 Protein of unknown function (DUF3710) 52 221 4.0E-55 T 28-03-2018 IPR022183 Protein of unknown function DUF3710 CP478_RS09490 6299c2acfeef56958961a2450c3d0a04 560 Pfam PF01740 STAS domain 443 553 1.2E-17 T 28-03-2018 IPR002645 STAS domain CP478_RS09490 6299c2acfeef56958961a2450c3d0a04 560 SUPERFAMILY SSF52091 446 558 3.73E-12 T 28-03-2018 IPR002645 STAS domain CP478_RS09490 6299c2acfeef56958961a2450c3d0a04 560 Gene3D G3DSA:3.30.750.24 422 560 3.3E-27 T 28-03-2018 IPR002645 STAS domain CP478_RS09490 6299c2acfeef56958961a2450c3d0a04 560 Pfam PF00916 Sulfate permease family 25 392 2.3E-103 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CP478_RS09490 6299c2acfeef56958961a2450c3d0a04 560 TIGRFAM TIGR00815 sulP: sulfate permease 14 553 4.0E-134 T 28-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 ProSitePatterns PS00455 Putative AMP-binding domain signature. 134 145 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Gene3D G3DSA:3.40.50.980 10 139 3.3E-16 T 28-03-2018 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Gene3D G3DSA:3.30.300.30 375 472 8.7E-28 T 28-03-2018 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Pfam PF13193 AMP-binding enzyme C-terminal domain 390 463 3.4E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Gene3D G3DSA:3.40.50.980 140 286 4.0E-40 T 28-03-2018 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Gene3D G3DSA:2.30.38.10 287 373 7.2E-27 T 28-03-2018 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 Pfam PF00501 AMP-binding enzyme 46 374 2.1E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS06535 ada370593e5ec7c62fa97e47492f9352 473 SUPERFAMILY SSF56801 19 471 1.96E-112 T 28-03-2018 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 PIRSF PIRSF016262 7 225 7.6E-67 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 80 132 5.0E-24 T 28-03-2018 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 41 208 4.6E-40 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 Pfam PF03099 Biotin/lipoate A/B protein ligase family 68 166 1.8E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 Hamap MF_00013 Octanoyltransferase [lipB]. 11 214 34.116 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 76 91 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 SUPERFAMILY SSF55681 10 214 4.81E-69 T 28-03-2018 CP478_RS12045 e899ad413d6f22ae4b25e65b8a413688 230 Gene3D G3DSA:3.30.930.10 5 212 4.7E-70 T 28-03-2018 CP478_RS05025 d6e3a82a16004052e2bfa621d920969a 439 Gene3D G3DSA:1.10.10.10 7 190 3.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05025 d6e3a82a16004052e2bfa621d920969a 439 Pfam PF00872 Transposase, Mutator family 33 405 2.3E-145 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS05025 d6e3a82a16004052e2bfa621d920969a 439 ProSitePatterns PS01007 Transposases, Mutator family, signature. 264 288 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 SUPERFAMILY SSF51905 148 314 1.05E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 SUPERFAMILY SSF55424 318 409 2.75E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 304 5.7E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.1E-16 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.1E-16 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 1.1E-16 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.1E-16 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Pfam PF14759 Reductase C-terminal 326 408 5.0E-12 T 28-03-2018 IPR028202 Reductase, C-terminal CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Gene3D G3DSA:3.30.390.30 319 411 1.1E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.2E-28 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.2E-28 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.2E-28 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.2E-28 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.2E-28 T 28-03-2018 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Gene3D G3DSA:3.50.50.60 183 315 3.0E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Gene3D G3DSA:3.50.50.60 128 182 1.5E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 SUPERFAMILY SSF51905 3 182 2.45E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10160 b2314e74f57f99a91e3f5ad799d2e5f4 411 Gene3D G3DSA:3.50.50.60 2 127 4.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10410 d4446dd3b190344d5280b20da6cf8120 250 SMART SM00849 21 215 1.9E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS10410 d4446dd3b190344d5280b20da6cf8120 250 Pfam PF00753 Metallo-beta-lactamase superfamily 18 212 7.2E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS10410 d4446dd3b190344d5280b20da6cf8120 250 Gene3D G3DSA:3.60.15.10 1 236 3.1E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS10410 d4446dd3b190344d5280b20da6cf8120 250 SUPERFAMILY SSF56281 3 234 1.02E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02305 442bcb172aa0243071cc231842c059a7 376 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 376 106.386 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS02305 442bcb172aa0243071cc231842c059a7 376 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 20 297 2.1E-94 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS02305 442bcb172aa0243071cc231842c059a7 376 SUPERFAMILY SSF55931 10 374 2.26E-113 T 28-03-2018 CP478_RS02305 442bcb172aa0243071cc231842c059a7 376 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 19 302 2.2E-120 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS20110 647aaab20f652f8ea32ed088f144a5f3 319 Gene3D G3DSA:3.60.21.10 48 299 1.1E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS20110 647aaab20f652f8ea32ed088f144a5f3 319 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 52 233 2.4E-10 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CP478_RS20110 647aaab20f652f8ea32ed088f144a5f3 319 SUPERFAMILY SSF56300 47 290 8.07E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 SUPERFAMILY SSF56655 10 262 8.12E-61 T 28-03-2018 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 Pfam PF00459 Inositol monophosphatase family 16 259 1.0E-51 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 1.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 1.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 Gene3D G3DSA:3.30.540.10 3 146 8.6E-28 T 28-03-2018 CP478_RS08775 a10157b4fadec7d51aab61a2058152fc 270 Gene3D G3DSA:3.40.190.80 147 270 3.1E-26 T 28-03-2018 CP478_RS00990 a9f6ff5c04f82ff3486ee492f8313598 244 Gene3D G3DSA:2.60.120.10 135 243 1.1E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS00990 a9f6ff5c04f82ff3486ee492f8313598 244 Pfam PF02678 Pirin 12 122 1.1E-37 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CP478_RS00990 a9f6ff5c04f82ff3486ee492f8313598 244 SUPERFAMILY SSF51182 6 235 1.3E-62 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS00990 a9f6ff5c04f82ff3486ee492f8313598 244 PIRSF PIRSF006232 1 236 3.0E-52 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CP478_RS00990 a9f6ff5c04f82ff3486ee492f8313598 244 Gene3D G3DSA:2.60.120.10 15 134 3.2E-47 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS12620 1159c8cec0475b738e27702c4ae7b942 457 SUPERFAMILY SSF111283 6 450 1.26E-60 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CP478_RS12620 1159c8cec0475b738e27702c4ae7b942 457 Gene3D G3DSA:3.30.2290.10 3 212 8.8E-27 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CP478_RS12620 1159c8cec0475b738e27702c4ae7b942 457 Pfam PF01523 Putative modulator of DNA gyrase 26 320 1.0E-26 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 SUPERFAMILY SSF51445 152 490 9.75E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 SUPERFAMILY SSF51445 519 595 9.75E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 SMART SM00642 177 587 1.8E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 112 6.0E-21 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Gene3D G3DSA:2.60.40.10 22 155 7.6E-52 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 22 718 7.5E-297 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 SUPERFAMILY SSF51011 609 718 7.19E-26 T 28-03-2018 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Pfam PF00128 Alpha amylase, catalytic domain 328 549 5.7E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Pfam PF00128 Alpha amylase, catalytic domain 207 295 1.9E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 SUPERFAMILY SSF81296 21 165 2.58E-41 T 28-03-2018 IPR014756 Immunoglobulin E-set CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Gene3D G3DSA:2.60.40.1180 600 720 9.5E-32 T 28-03-2018 CP478_RS08565 b09340b5517c1c3534b0195350c8ba82 721 Gene3D G3DSA:3.20.20.80 156 599 1.9E-110 T 28-03-2018 CP478_RS12305 bd3eab69a4192d5db48cbc5420631244 502 Gene3D G3DSA:3.60.110.10 214 469 9.0E-34 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS12305 bd3eab69a4192d5db48cbc5420631244 502 Pfam PF00795 Carbon-nitrogen hydrolase 222 460 3.5E-17 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS12305 bd3eab69a4192d5db48cbc5420631244 502 SUPERFAMILY SSF56317 219 472 2.35E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS12305 bd3eab69a4192d5db48cbc5420631244 502 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 11 478 13.851 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CP478_RS12305 bd3eab69a4192d5db48cbc5420631244 502 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 66 440 3.9E-99 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CP478_RS05965 93832297af5f185c447e27c8b7fb8eec 106 Pfam PF01255 Putative undecaprenyl diphosphate synthase 18 47 9.6E-7 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05965 93832297af5f185c447e27c8b7fb8eec 106 SUPERFAMILY SSF64005 3 68 6.41E-11 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05965 93832297af5f185c447e27c8b7fb8eec 106 Gene3D G3DSA:3.40.1180.10 3 48 2.0E-8 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS15560 8c1f904194d10a64918709c46a9c6398 530 Gene3D G3DSA:1.20.1250.20 48 241 3.4E-29 T 28-03-2018 CP478_RS15560 8c1f904194d10a64918709c46a9c6398 530 SUPERFAMILY SSF103473 37 239 2.62E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS15560 8c1f904194d10a64918709c46a9c6398 530 SUPERFAMILY SSF103473 287 512 2.62E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS15560 8c1f904194d10a64918709c46a9c6398 530 Gene3D G3DSA:1.20.1250.20 291 526 6.5E-21 T 28-03-2018 CP478_RS15560 8c1f904194d10a64918709c46a9c6398 530 Pfam PF07690 Major Facilitator Superfamily 61 449 2.7E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 TIGRFAM TIGR03968 mycofact_TetR: mycofactocin system transcriptional regulator 6 193 4.2E-89 T 28-03-2018 IPR023851 Transcriptional regulator, TetR-type CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 SUPERFAMILY SSF46689 6 78 2.46E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 6.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 6.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 Gene3D G3DSA:1.10.10.60 2 58 6.4E-16 T 28-03-2018 CP478_RS03735 aa264e316f1bdb1d03b9ad77578c6b82 198 Gene3D G3DSA:1.10.357.10 59 192 1.5E-19 T 28-03-2018 CP478_RS03075 df95a2ec8d18069c9fe5f5294adb951a 380 SMART SM00854 9 291 4.5E-108 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CP478_RS03075 df95a2ec8d18069c9fe5f5294adb951a 380 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 9 291 1.2E-73 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CP478_RS03075 df95a2ec8d18069c9fe5f5294adb951a 380 SUPERFAMILY SSF56300 60 312 8.22E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS03075 df95a2ec8d18069c9fe5f5294adb951a 380 SUPERFAMILY SSF56300 8 19 8.22E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS03075 df95a2ec8d18069c9fe5f5294adb951a 380 Gene3D G3DSA:3.60.21.10 2 352 2.1E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 Gene3D G3DSA:1.20.1250.20 257 495 2.9E-22 T 28-03-2018 CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 SUPERFAMILY SSF103473 461 485 1.23E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 SUPERFAMILY SSF103473 253 425 1.23E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 SUPERFAMILY SSF103473 13 203 1.23E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 429 2.9E-80 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 Gene3D G3DSA:1.20.1250.20 12 205 1.6E-35 T 28-03-2018 CP478_RS06845 ae21fccd97df2b3f89b9e1f1b41ea612 579 Pfam PF07690 Major Facilitator Superfamily 25 415 2.6E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 Gene3D G3DSA:3.40.50.980 174 351 1.3E-28 T 28-03-2018 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 Gene3D G3DSA:2.30.38.10 374 460 6.6E-19 T 28-03-2018 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 Pfam PF00501 AMP-binding enzyme 13 467 1.0E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 SUPERFAMILY SSF56801 5 568 1.23E-93 T 28-03-2018 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 Gene3D G3DSA:3.30.300.30 461 566 2.9E-13 T 28-03-2018 CP478_RS20900 2b5099a1e93e27c9430ad89c4ca9c1f8 584 Gene3D G3DSA:3.40.50.980 3 173 1.1E-28 T 28-03-2018 CP478_RS16885 182a0fc2cc08413249334be6d9570552 472 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 268 1.1E-89 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS16885 182a0fc2cc08413249334be6d9570552 472 Gene3D G3DSA:3.30.559.10 4 190 1.9E-5 T 28-03-2018 CP478_RS16885 182a0fc2cc08413249334be6d9570552 472 SUPERFAMILY SSF52777 36 169 3.04E-10 T 28-03-2018 CP478_RS16885 182a0fc2cc08413249334be6d9570552 472 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 461 1.5E-153 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS16885 182a0fc2cc08413249334be6d9570552 472 Pfam PF06974 Protein of unknown function (DUF1298) 309 457 1.6E-20 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 SUPERFAMILY SSF90123 29 67 2.88E-82 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 SUPERFAMILY SSF90123 107 386 2.88E-82 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 Pfam PF00664 ABC transporter transmembrane region 55 353 6.3E-66 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 Gene3D G3DSA:1.20.1560.10 17 386 1.0E-81 T 28-03-2018 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 SUPERFAMILY SSF52540 388 629 1.46E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 Gene3D G3DSA:3.40.50.300 394 629 7.4E-70 T 28-03-2018 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 Pfam PF00005 ABC transporter 414 562 2.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 ProSitePatterns PS00211 ABC transporters family signature. 534 548 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS06960 6c76967f5d04ec361427a77d1f6cee5f 631 SMART SM00382 422 594 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS00885 38d64c06929af121f89c359c150a333b 449 Pfam PF01565 FAD binding domain 37 173 5.4E-34 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 Pfam PF02913 FAD linked oxidases, C-terminal domain 211 444 9.0E-55 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 SUPERFAMILY SSF55103 215 448 3.43E-39 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 Gene3D G3DSA:1.10.45.10 408 447 5.0E-10 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 Gene3D G3DSA:3.30.43.10 1 88 1.5E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 Gene3D G3DSA:3.30.465.10 94 235 1.4E-34 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS00885 38d64c06929af121f89c359c150a333b 449 SUPERFAMILY SSF56176 2 212 3.27E-61 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.781 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 SUPERFAMILY SSF50104 1 112 2.11E-45 T 28-03-2018 IPR008991 Translation protein SH3-like domain CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 7.5E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 Pfam PF01245 Ribosomal protein L19 6 112 2.5E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 PRINTS PR00061 Ribosomal protein L19 signature 87 112 3.5E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 PRINTS PR00061 Ribosomal protein L19 signature 3 32 3.5E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 PRINTS PR00061 Ribosomal protein L19 signature 33 62 3.5E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15865 e7c0140045d6867ece67e251f404ced7 113 PIRSF PIRSF002191 1 113 7.9E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18475 8e7835e2f2a27db002bd9b06980c06b1 213 Pfam PF00378 Enoyl-CoA hydratase/isomerase 46 213 7.7E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS18475 8e7835e2f2a27db002bd9b06980c06b1 213 Gene3D G3DSA:3.90.226.10 23 213 1.7E-50 T 28-03-2018 CP478_RS18475 8e7835e2f2a27db002bd9b06980c06b1 213 SUPERFAMILY SSF52096 39 213 1.18E-49 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS18475 8e7835e2f2a27db002bd9b06980c06b1 213 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 138 158 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS11895 427279f7eb5eea861e54b9ef3f96a83f 385 Pfam PF00534 Glycosyl transferases group 1 188 360 2.2E-44 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS11895 427279f7eb5eea861e54b9ef3f96a83f 385 SUPERFAMILY SSF53756 4 379 1.3E-76 T 28-03-2018 CP478_RS11895 427279f7eb5eea861e54b9ef3f96a83f 385 Gene3D G3DSA:3.40.50.2000 187 363 1.6E-51 T 28-03-2018 CP478_RS11895 427279f7eb5eea861e54b9ef3f96a83f 385 Pfam PF13439 Glycosyltransferase Family 4 16 177 7.3E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS11895 427279f7eb5eea861e54b9ef3f96a83f 385 Gene3D G3DSA:3.40.50.2000 2 186 3.3E-6 T 28-03-2018 CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 Pfam PF04452 RNA methyltransferase 20 240 8.6E-60 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 SUPERFAMILY SSF88697 5 71 1.34E-11 T 28-03-2018 IPR015947 PUA-like domain CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 SUPERFAMILY SSF75217 74 248 1.1E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 Gene3D G3DSA:2.40.240.20 1 71 8.0E-18 T 28-03-2018 CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 Gene3D G3DSA:3.40.1280.10 73 262 2.2E-54 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 PIRSF PIRSF015601 2 247 6.4E-44 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS12935 5fc59bc3bbd71181c5d1ff334af3b203 262 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 8 243 3.2E-32 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 SMART SM00342 250 332 2.1E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 Gene3D G3DSA:1.10.10.60 294 334 3.8E-13 T 28-03-2018 CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 Pfam PF12833 Helix-turn-helix domain 256 333 5.8E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 Gene3D G3DSA:1.10.10.10 144 293 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 207 4.2E-38 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CP478_RS16860 ceb54e81daacb6d0d5835ef8cb717598 340 SUPERFAMILY SSF46689 286 333 2.24E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 ProSitePatterns PS00674 AAA-protein family signature. 302 320 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 8 610 36.162 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 Gene3D G3DSA:3.40.50.300 144 343 1.1E-64 T 28-03-2018 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 SUPERFAMILY SSF140990 413 606 2.88E-68 T 28-03-2018 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 Pfam PF01434 Peptidase family M41 395 601 7.7E-79 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 Gene3D G3DSA:1.10.8.60 344 404 9.2E-18 T 28-03-2018 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 SMART SM00382 195 334 3.0E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 331 1.4E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 SUPERFAMILY SSF52540 155 403 2.84E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19710 d813b25e24b79c01fb6aaca04efdb9f1 760 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 115 602 4.1E-230 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Gene3D G3DSA:3.30.300.20 262 331 3.4E-16 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 SUPERFAMILY SSF54814 263 326 1.83E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Gene3D G3DSA:3.30.1480.10 1 99 1.4E-28 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 SUPERFAMILY SSF50249 109 183 4.71E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 SMART SM00316 110 182 0.0045 T 28-03-2018 IPR022967 RNA-binding domain, S1 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 SUPERFAMILY SSF69705 1 99 1.96E-28 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Pfam PF08529 NusA N-terminal domain 6 61 1.9E-8 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Pfam PF08529 NusA N-terminal domain 64 100 5.3E-6 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Gene3D G3DSA:2.40.50.140 112 182 2.2E-10 T 28-03-2018 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Gene3D G3DSA:3.30.300.20 183 260 2.9E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Pfam PF13184 NusA-like KH domain 214 281 1.8E-25 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 326 1.2E-109 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 347 25.901 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CP478_RS15535 683c078e74b152289055cb880c82ad2e 347 SUPERFAMILY SSF54814 184 262 1.64E-27 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CP478_RS14665 be2d8cdfce2cc6ca90706bc3e5a66289 136 SUPERFAMILY SSF51316 7 133 6.8E-56 T 28-03-2018 IPR011057 Mss4-like CP478_RS14665 be2d8cdfce2cc6ca90706bc3e5a66289 136 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 8 134 1.4E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CP478_RS14665 be2d8cdfce2cc6ca90706bc3e5a66289 136 Gene3D G3DSA:2.170.150.20 1 136 1.6E-57 T 28-03-2018 CP478_RS14665 be2d8cdfce2cc6ca90706bc3e5a66289 136 Pfam PF01641 SelR domain 12 132 1.8E-52 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 Gene3D G3DSA:1.20.1250.20 1 196 3.8E-32 T 28-03-2018 CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 Gene3D G3DSA:1.20.1250.20 249 508 3.0E-27 T 28-03-2018 CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 SUPERFAMILY SSF103473 478 506 4.32E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 SUPERFAMILY SSF103473 2 192 4.32E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 SUPERFAMILY SSF103473 244 414 4.32E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS13435 a22dc81cac958af531f50f0634c28efa 508 Pfam PF07690 Major Facilitator Superfamily 14 404 9.7E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS03900 8cd6c8e7c595d71937694fe14fb098d6 122 Gene3D G3DSA:3.30.420.100 3 122 1.4E-38 T 28-03-2018 CP478_RS03900 8cd6c8e7c595d71937694fe14fb098d6 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 8 122 26.363 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03900 8cd6c8e7c595d71937694fe14fb098d6 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 12 122 3.9E-37 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03900 8cd6c8e7c595d71937694fe14fb098d6 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 8 122 2.0E-47 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03900 8cd6c8e7c595d71937694fe14fb098d6 122 SUPERFAMILY SSF53137 9 120 6.98E-47 T 28-03-2018 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 SMART SM01133 9 222 5.1E-79 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 PIRSF PIRSF001357 4 223 2.2E-65 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 SUPERFAMILY SSF51569 6 222 2.09E-67 T 28-03-2018 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 8 224 32.013 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 9 216 8.1E-62 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 Gene3D G3DSA:3.20.20.70 3 223 9.8E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS02550 e9d527a792c298f19be75f20e2de399a 224 Pfam PF01791 DeoC/LacD family aldolase 13 218 1.3E-18 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CP478_RS12495 203138b6e53024abeb7bca0d5e86878f 310 Pfam PF00753 Metallo-beta-lactamase superfamily 70 268 2.7E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12495 203138b6e53024abeb7bca0d5e86878f 310 Gene3D G3DSA:3.60.15.10 49 310 1.5E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12495 203138b6e53024abeb7bca0d5e86878f 310 SMART SM00849 69 298 3.3E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12495 203138b6e53024abeb7bca0d5e86878f 310 SUPERFAMILY SSF56281 50 302 3.01E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 Gene3D G3DSA:3.40.50.2000 184 370 5.2E-41 T 28-03-2018 CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 SUPERFAMILY SSF53756 1 385 7.07E-81 T 28-03-2018 CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 Gene3D G3DSA:3.40.50.2000 1 183 2.1E-15 T 28-03-2018 CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 Pfam PF00534 Glycosyl transferases group 1 193 364 9.0E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 386 2.2E-202 T 28-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 CP478_RS06640 79086d1f8a08db0d1646d2e1c6619fcf 387 Pfam PF13439 Glycosyltransferase Family 4 15 176 2.7E-28 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS08785 dfeafc9eacbfdadf31f6e4a9650b405a 115 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 1.1E-33 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CP478_RS08785 dfeafc9eacbfdadf31f6e4a9650b405a 115 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 30.783 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CP478_RS08785 dfeafc9eacbfdadf31f6e4a9650b405a 115 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 2.0E-25 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CP478_RS08785 dfeafc9eacbfdadf31f6e4a9650b405a 115 SUPERFAMILY SSF141734 7 109 9.29E-45 T 28-03-2018 CP478_RS08535 4d2a6695a6c9668b39cca34c4d04045e 148 Pfam PF04075 F420H(2)-dependent quinone reductase 14 143 6.6E-58 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS08535 4d2a6695a6c9668b39cca34c4d04045e 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 2.8E-41 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS08535 4d2a6695a6c9668b39cca34c4d04045e 148 SUPERFAMILY SSF50475 33 145 3.75E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS08535 4d2a6695a6c9668b39cca34c4d04045e 148 Gene3D G3DSA:2.30.110.10 7 144 5.1E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS15805 ae5f082ae41af67dae650c4802d9ef6d 404 SUPERFAMILY SSF140459 2 168 2.88E-63 T 28-03-2018 CP478_RS15805 ae5f082ae41af67dae650c4802d9ef6d 404 Gene3D G3DSA:1.10.287.1060 18 98 2.8E-5 T 28-03-2018 CP478_RS15805 ae5f082ae41af67dae650c4802d9ef6d 404 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 321 400 2.3E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS15805 ae5f082ae41af67dae650c4802d9ef6d 404 Pfam PF00823 PPE family 1 157 1.2E-63 T 28-03-2018 IPR000030 PPE family CP478_RS12145 57111dca854b0493facf08fc3d8dce5f 291 SUPERFAMILY SSF56784 77 278 3.17E-45 T 28-03-2018 IPR023214 HAD-like domain CP478_RS12145 57111dca854b0493facf08fc3d8dce5f 291 Pfam PF13419 Haloacid dehalogenase-like hydrolase 82 258 2.7E-31 T 28-03-2018 IPR023214 HAD-like domain CP478_RS12145 57111dca854b0493facf08fc3d8dce5f 291 Gene3D G3DSA:3.40.50.1000 148 291 1.4E-26 T 28-03-2018 IPR023214 HAD-like domain CP478_RS12145 57111dca854b0493facf08fc3d8dce5f 291 Gene3D G3DSA:1.10.150.240 93 147 1.7E-14 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 SUPERFAMILY SSF103025 17 269 5.97E-52 T 28-03-2018 CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 215 280 3.5E-17 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 PIRSF PIRSF006487 13 333 7.0E-14 T 28-03-2018 CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 254 325 2.0E-5 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 Pfam PF01571 Aminomethyltransferase folate-binding domain 18 240 6.8E-22 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 Gene3D G3DSA:3.30.70.1400 41 267 1.9E-26 T 28-03-2018 CP478_RS04400 d570c3371a39ae4ca1294c0a6f119e24 368 Gene3D G3DSA:2.40.30.110 269 343 6.9E-8 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 SMART SM00419 167 215 1.2E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 1.6E-23 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 SMART SM00100 10 128 8.2E-29 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 SUPERFAMILY SSF46785 145 223 2.04E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 Gene3D G3DSA:1.10.10.10 144 224 9.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.3E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 SUPERFAMILY SSF51206 4 142 1.44E-36 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS20070 be9694e288fcb66ab93a3a623f9d98d9 224 Gene3D G3DSA:2.60.120.10 1 143 5.0E-37 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS05300 12ea50f9b5f059195f778517f04c5a16 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 261 8.5E-43 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS05300 12ea50f9b5f059195f778517f04c5a16 269 SUPERFAMILY SSF52096 14 262 3.17E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS05300 12ea50f9b5f059195f778517f04c5a16 269 Gene3D G3DSA:3.90.226.10 12 269 1.2E-67 T 28-03-2018 CP478_RS01205 7b4317bc2835afcd5349693ffa01cb01 487 Pfam PF00171 Aldehyde dehydrogenase family 17 478 1.5E-165 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS01205 7b4317bc2835afcd5349693ffa01cb01 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS01205 7b4317bc2835afcd5349693ffa01cb01 487 Gene3D G3DSA:3.40.309.10 272 464 2.0E-68 T 28-03-2018 CP478_RS01205 7b4317bc2835afcd5349693ffa01cb01 487 Gene3D G3DSA:3.40.605.10 3 271 1.2E-90 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS01205 7b4317bc2835afcd5349693ffa01cb01 487 SUPERFAMILY SSF53720 6 481 5.11E-159 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 SMART SM00829 10 320 1.7E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 SUPERFAMILY SSF50129 1 139 1.11E-32 T 28-03-2018 IPR011032 GroES-like CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 Gene3D G3DSA:3.40.50.720 142 261 3.7E-24 T 28-03-2018 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 SUPERFAMILY SSF51735 116 272 1.0E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 Gene3D G3DSA:3.90.180.10 1 141 1.9E-33 T 28-03-2018 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 Pfam PF00107 Zinc-binding dehydrogenase 150 265 2.9E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS00805 ca5ad51722f27d4b7b3dae98bf466f73 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 86 1.6E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS05790 573e1b625fe5e68eb1351d790bff7498 64 SUPERFAMILY SSF56349 2 34 1.85E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 293 529 2.6E-73 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 Pfam PF02355 Protein export membrane protein 366 539 2.9E-8 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 Gene3D G3DSA:1.20.1640.10 311 543 5.1E-26 T 28-03-2018 CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 550 38.194 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 SUPERFAMILY SSF82866 343 540 1.7E-28 T 28-03-2018 CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 537 4.2E-146 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CP478_RS14175 3ee9c7c7e2464543972cfa729769f14f 573 Pfam PF07549 SecD/SecF GG Motif 39 57 4.1E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 7.1E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 7.1E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 7.1E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 Gene3D G3DSA:1.10.10.10 3 99 1.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 Pfam PF01022 Bacterial regulatory protein, arsR family 24 67 1.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 ProSitePatterns PS00380 Rhodanese signature 1. 143 154 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 SUPERFAMILY SSF52821 110 217 3.8E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 SMART SM00418 14 95 3.6E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 SUPERFAMILY SSF46785 9 163 2.82E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 Pfam PF00581 Rhodanese-like domain 120 210 1.5E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 Gene3D G3DSA:3.40.250.10 100 218 2.3E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS09145 a26f7abcb2aa2622f1cff1d18f763f9c 218 SMART SM00450 118 214 2.3E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS02885 07ca19c984d1dbf96350f2d0790d9cec 548 Gene3D G3DSA:3.30.420.40 139 523 4.3E-5 T 28-03-2018 CP478_RS02885 07ca19c984d1dbf96350f2d0790d9cec 548 PRINTS PR01217 Proline rich extensin signature 435 460 1.2E-12 T 28-03-2018 CP478_RS02885 07ca19c984d1dbf96350f2d0790d9cec 548 PRINTS PR01217 Proline rich extensin signature 320 336 1.2E-12 T 28-03-2018 CP478_RS02885 07ca19c984d1dbf96350f2d0790d9cec 548 PRINTS PR01217 Proline rich extensin signature 375 396 1.2E-12 T 28-03-2018 CP478_RS02885 07ca19c984d1dbf96350f2d0790d9cec 548 PRINTS PR01217 Proline rich extensin signature 415 432 1.2E-12 T 28-03-2018 CP478_RS02275 cb657afca28dca3b9f69b7bf30e51d43 291 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 24 288 3.0E-83 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CP478_RS02275 cb657afca28dca3b9f69b7bf30e51d43 291 SUPERFAMILY SSF56219 24 288 2.09E-70 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS02275 cb657afca28dca3b9f69b7bf30e51d43 291 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 24 287 1.1E-57 T 28-03-2018 CP478_RS02275 cb657afca28dca3b9f69b7bf30e51d43 291 Gene3D G3DSA:3.60.10.10 23 289 6.4E-45 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS02275 cb657afca28dca3b9f69b7bf30e51d43 291 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 27 281 1.1E-20 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS09435 b60043df895764cbd20fa34115752144 517 Gene3D G3DSA:3.40.710.10 46 393 5.4E-77 T 28-03-2018 CP478_RS09435 b60043df895764cbd20fa34115752144 517 SUPERFAMILY SSF56601 56 389 1.53E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS09435 b60043df895764cbd20fa34115752144 517 Pfam PF00144 Beta-lactamase 60 383 3.7E-69 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS18425 3f71ebddbac19d67825b00b3afa82bff 130 Pfam PF03259 Roadblock/LC7 domain 10 100 8.0E-24 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CP478_RS18425 3f71ebddbac19d67825b00b3afa82bff 130 Gene3D G3DSA:3.30.450.30 7 130 5.2E-38 T 28-03-2018 CP478_RS18425 3f71ebddbac19d67825b00b3afa82bff 130 SUPERFAMILY SSF103196 8 127 3.79E-32 T 28-03-2018 CP478_RS18425 3f71ebddbac19d67825b00b3afa82bff 130 SMART SM00960 11 101 6.1E-29 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CP478_RS01210 d37d671d5bbe6061c9dad5c83d92169f 254 Pfam PF08241 Methyltransferase domain 63 155 5.6E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS01210 d37d671d5bbe6061c9dad5c83d92169f 254 SUPERFAMILY SSF53335 32 229 1.88E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01210 d37d671d5bbe6061c9dad5c83d92169f 254 Gene3D G3DSA:3.40.50.150 8 238 4.9E-21 T 28-03-2018 CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 28-03-2018 IPR019808 Histidine triad, conserved site CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 SUPERFAMILY SSF54197 1 132 6.81E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 Pfam PF01230 HIT domain 11 106 1.0E-26 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 PRINTS PR00332 Histidine triad family signature 92 102 2.3E-15 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 PRINTS PR00332 Histidine triad family signature 4 20 2.3E-15 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 PRINTS PR00332 Histidine triad family signature 25 43 2.3E-15 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS06905 e21c855461ffa4968ee8ce987a8ff486 144 Gene3D G3DSA:3.30.428.10 1 144 9.3E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS13130 a5d92104dd03afe785800948cb033251 142 SUPERFAMILY SSF54631 1 140 2.15E-31 T 28-03-2018 CP478_RS13130 a5d92104dd03afe785800948cb033251 142 SMART SM00116 13 60 6.9E-7 T 28-03-2018 IPR000644 CBS domain CP478_RS13130 a5d92104dd03afe785800948cb033251 142 SMART SM00116 78 125 4.4E-8 T 28-03-2018 IPR000644 CBS domain CP478_RS13130 a5d92104dd03afe785800948cb033251 142 Pfam PF00571 CBS domain 14 59 3.1E-9 T 28-03-2018 IPR000644 CBS domain CP478_RS13130 a5d92104dd03afe785800948cb033251 142 Pfam PF00571 CBS domain 71 123 2.0E-10 T 28-03-2018 IPR000644 CBS domain CP478_RS13130 a5d92104dd03afe785800948cb033251 142 Gene3D G3DSA:3.10.580.10 1 135 8.0E-27 T 28-03-2018 CP478_RS11970 8b565803b7570684346cf340c06d2f9d 324 Pfam PF00294 pfkB family carbohydrate kinase 15 295 6.4E-54 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CP478_RS11970 8b565803b7570684346cf340c06d2f9d 324 SUPERFAMILY SSF53613 2 297 1.51E-54 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS11970 8b565803b7570684346cf340c06d2f9d 324 Gene3D G3DSA:3.40.1190.20 1 322 1.5E-41 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS11970 8b565803b7570684346cf340c06d2f9d 324 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CP478_RS02775 5c9c4bcf3139c6f24352913369fba8f1 300 Gene3D G3DSA:3.40.50.1820 67 300 3.6E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02775 5c9c4bcf3139c6f24352913369fba8f1 300 SUPERFAMILY SSF53474 72 299 1.35E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02775 5c9c4bcf3139c6f24352913369fba8f1 300 Pfam PF00756 Putative esterase 90 297 1.6E-7 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 476 551 2.7E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 SUPERFAMILY SSF56801 68 560 1.44E-126 T 28-03-2018 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 224 235 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Gene3D G3DSA:3.40.50.980 63 228 3.4E-31 T 28-03-2018 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Gene3D G3DSA:3.40.50.980 229 380 5.9E-35 T 28-03-2018 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Gene3D G3DSA:2.30.38.10 381 460 6.5E-14 T 28-03-2018 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Gene3D G3DSA:3.30.300.30 461 560 2.2E-30 T 28-03-2018 CP478_RS01455 211687499e27c0dfe56a0a9c467e652e 560 Pfam PF00501 AMP-binding enzyme 69 467 1.6E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Gene3D G3DSA:3.30.1490.20 16 210 3.4E-41 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 SUPERFAMILY SSF56059 17 346 2.83E-97 T 28-03-2018 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Gene3D G3DSA:3.50.30.10 359 488 2.7E-29 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 79 259 3.4E-26 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 269 320 3.3E-5 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 SUPERFAMILY SSF52009 354 463 2.75E-29 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Gene3D G3DSA:1.10.189.10 310 356 2.5E-12 T 28-03-2018 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Pfam PF00391 PEP-utilising enzyme, mobile domain 389 458 2.6E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CP478_RS06170 d9823cb58dbb84d61a8ef848391a03ea 490 Gene3D G3DSA:3.30.470.20 211 308 9.8E-17 T 28-03-2018 CP478_RS16410 05d31aaf3167d8b3766a3ce94880063b 321 Gene3D G3DSA:3.40.190.10 5 275 5.4E-4 T 28-03-2018 CP478_RS16410 05d31aaf3167d8b3766a3ce94880063b 321 Pfam PF07485 Domain of Unknown Function (DUF1259) 53 173 2.2E-40 T 28-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CP478_RS16410 05d31aaf3167d8b3766a3ce94880063b 321 Pfam PF07485 Domain of Unknown Function (DUF1259) 196 314 2.5E-41 T 28-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CP478_RS14360 3919bf5fee2ef8c7d2fb01bf56f10cc8 224 SUPERFAMILY SSF46785 17 193 7.39E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14360 3919bf5fee2ef8c7d2fb01bf56f10cc8 224 Pfam PF12840 Helix-turn-helix domain 17 67 1.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14360 3919bf5fee2ef8c7d2fb01bf56f10cc8 224 Gene3D G3DSA:3.30.1380.20 90 205 4.8E-5 T 28-03-2018 CP478_RS14360 3919bf5fee2ef8c7d2fb01bf56f10cc8 224 Gene3D G3DSA:1.10.10.10 14 89 8.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 SUPERFAMILY SSF53474 2 255 1.89E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 PRINTS PR00412 Epoxide hydrolase signature 25 40 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 PRINTS PR00412 Epoxide hydrolase signature 198 214 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 PRINTS PR00412 Epoxide hydrolase signature 231 253 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 PRINTS PR00412 Epoxide hydrolase signature 5 23 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 Gene3D G3DSA:3.40.50.1820 1 257 1.3E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19005 e0a640c022b130ab9e1ea0e478535f08 261 Pfam PF12697 Alpha/beta hydrolase family 1 247 4.0E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19020 17531ec74f3920309e42874090f0aa4a 98 Gene3D G3DSA:1.10.287.1060 1 96 6.4E-6 T 28-03-2018 CP478_RS19020 17531ec74f3920309e42874090f0aa4a 98 Pfam PF00934 PE family 4 92 7.8E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19020 17531ec74f3920309e42874090f0aa4a 98 SUPERFAMILY SSF140459 7 83 1.41E-24 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 SUPERFAMILY SSF52021 2 138 5.62E-50 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 297 308 7.9E-31 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 185 199 7.9E-31 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 224 238 7.9E-31 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 255 271 7.9E-31 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 272 289 7.9E-31 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 Pfam PF00117 Glutamine amidotransferase class-I 189 369 1.2E-37 T 28-03-2018 IPR017926 Glutamine amidotransferase CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00097 Anthranilate synthase component II signature 255 266 5.9E-6 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00097 Anthranilate synthase component II signature 227 236 5.9E-6 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00097 Anthranilate synthase component II signature 346 359 5.9E-6 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 375 44.033 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 132 9.3E-48 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 SUPERFAMILY SSF52317 152 373 2.45E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 371 9.7E-130 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 Gene3D G3DSA:3.50.30.20 1 148 7.0E-58 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 Gene3D G3DSA:3.40.50.880 149 375 1.0E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 SMART SM01097 2 134 9.3E-77 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 255 266 2.3E-11 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 227 236 2.3E-11 T 28-03-2018 CP478_RS07580 95f970bfc0b07dfb2f92ff2c0cd1aed5 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 346 359 2.3E-11 T 28-03-2018 CP478_RS06885 24cb718b3715809aaa213084df5abf3f 419 Gene3D G3DSA:1.20.1250.20 1 204 4.1E-15 T 28-03-2018 CP478_RS06885 24cb718b3715809aaa213084df5abf3f 419 SUPERFAMILY SSF103473 1 398 7.19E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS06885 24cb718b3715809aaa213084df5abf3f 419 Pfam PF07690 Major Facilitator Superfamily 12 363 2.0E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS06885 24cb718b3715809aaa213084df5abf3f 419 Gene3D G3DSA:1.20.1250.20 211 402 1.2E-20 T 28-03-2018 CP478_RS12060 919161b96a491855732a555904b3dae6 140 PIRSF PIRSF021697 1 140 1.6E-59 T 28-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane CP478_RS12060 919161b96a491855732a555904b3dae6 140 Pfam PF06271 RDD family 25 116 3.0E-8 T 28-03-2018 IPR010432 RDD CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF01469 Pentapeptide repeats (8 copies) 443 481 3.6E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF01469 Pentapeptide repeats (8 copies) 321 360 1.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF01469 Pentapeptide repeats (8 copies) 483 521 2.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF01469 Pentapeptide repeats (8 copies) 403 441 2.2E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF01469 Pentapeptide repeats (8 copies) 365 401 1.0E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Pfam PF00823 PPE family 6 163 5.8E-59 T 28-03-2018 IPR000030 PPE family CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 Gene3D G3DSA:1.10.287.1060 24 107 1.9E-7 T 28-03-2018 CP478_RS04105 bc4dc093a6f17e43e10267e903e50b8a 645 SUPERFAMILY SSF140459 4 172 8.11E-59 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PIRSF PIRSF000350 1 464 1.8E-69 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Gene3D G3DSA:3.50.50.60 1 162 9.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 SUPERFAMILY SSF51905 1 318 1.3E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 1 461 62.553 T 28-03-2018 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 4.1E-57 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 SUPERFAMILY SSF55424 344 463 1.2E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Gene3D G3DSA:3.50.50.60 277 338 1.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Gene3D G3DSA:3.50.50.60 163 276 2.6E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 452 2.0E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.4E-31 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.4E-31 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.4E-31 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 1.4E-31 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.4E-31 T 28-03-2018 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 325 2.5E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14870 18803a388ed581746dbeba96ea461381 468 Gene3D G3DSA:3.30.390.30 339 462 1.4E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS12505 488b029068a519adba0f89d05c6977be 80 SUPERFAMILY SSF50118 1 77 6.08E-30 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS12505 488b029068a519adba0f89d05c6977be 80 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 7.4E-28 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 CP478_RS05850 42b3b96ca7b0d8996b23167390b6f459 131 Pfam PF00581 Rhodanese-like domain 26 116 1.0E-6 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS05850 42b3b96ca7b0d8996b23167390b6f459 131 SMART SM00450 17 122 7.4E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS05850 42b3b96ca7b0d8996b23167390b6f459 131 SUPERFAMILY SSF52821 13 118 6.68E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS05850 42b3b96ca7b0d8996b23167390b6f459 131 Gene3D G3DSA:3.40.250.10 1 124 1.2E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS09750 051b5c2d0be14c76aaa4d1987f2c97eb 350 Pfam PF00823 PPE family 5 161 6.0E-62 T 28-03-2018 IPR000030 PPE family CP478_RS09750 051b5c2d0be14c76aaa4d1987f2c97eb 350 SUPERFAMILY SSF140459 2 174 4.97E-64 T 28-03-2018 CP478_RS09750 051b5c2d0be14c76aaa4d1987f2c97eb 350 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 267 345 2.7E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 6.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 6.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 6.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 6 270 3.1E-112 T 28-03-2018 IPR023985 Mycofactocin-dependent oxidoreductase CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 268 6.0E-48 T 28-03-2018 CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 6.1E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 Gene3D G3DSA:3.40.50.720 2 271 3.0E-67 T 28-03-2018 CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS15070 67b6c795394181dc3a5bd73845161568 272 SUPERFAMILY SSF51735 5 270 1.83E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01215 8de903672994e04ce6368c5cafc19adc 384 Gene3D G3DSA:3.40.50.2000 8 177 6.3E-8 T 28-03-2018 CP478_RS01215 8de903672994e04ce6368c5cafc19adc 384 SUPERFAMILY SSF53756 7 373 1.23E-70 T 28-03-2018 CP478_RS01215 8de903672994e04ce6368c5cafc19adc 384 Pfam PF13439 Glycosyltransferase Family 4 21 186 2.3E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS01215 8de903672994e04ce6368c5cafc19adc 384 Pfam PF00534 Glycosyl transferases group 1 200 353 1.1E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CP478_RS01215 8de903672994e04ce6368c5cafc19adc 384 Gene3D G3DSA:3.40.50.2000 178 358 2.7E-39 T 28-03-2018 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 78 91 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 44 59 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 SUPERFAMILY SSF51717 38 307 4.06E-76 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 Pfam PF00809 Pterin binding enzyme 45 289 1.5E-72 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 44 303 4.1E-89 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CP478_RS06615 d3bb380333715c7148ce5a67e3123c8b 318 Gene3D G3DSA:3.20.20.20 29 318 2.4E-83 T 28-03-2018 CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 Pfam PF00934 PE family 1 93 2.0E-32 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 PRINTS PR01228 Eggshell protein signature 223 234 2.0E-5 T 28-03-2018 CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 PRINTS PR01228 Eggshell protein signature 339 357 2.0E-5 T 28-03-2018 CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 PRINTS PR01228 Eggshell protein signature 285 300 2.0E-5 T 28-03-2018 CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 PRINTS PR01228 Eggshell protein signature 312 322 2.0E-5 T 28-03-2018 CP478_RS08045 d91beab8d405faa3d806cde1f7692337 370 SUPERFAMILY SSF140459 9 84 7.85E-24 T 28-03-2018 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 127 144 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 243 29.148 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 Gene3D G3DSA:3.30.360.10 122 211 9.3E-36 T 28-03-2018 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 42 243 1.6E-57 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 105 1.9E-22 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 SUPERFAMILY SSF51735 1 132 5.9E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 PIRSF PIRSF000161 1 245 9.2E-62 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 108 235 7.2E-31 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 SUPERFAMILY SSF55347 106 214 7.63E-42 T 28-03-2018 CP478_RS15190 32fa3669a38c3b0b83718b7b07814861 245 Gene3D G3DSA:3.40.50.720 1 121 4.4E-22 T 28-03-2018 CP478_RS02660 17912a32ae25443c75a0c97ba2e861ea 280 SUPERFAMILY SSF51658 4 256 1.93E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CP478_RS02660 17912a32ae25443c75a0c97ba2e861ea 280 Gene3D G3DSA:3.20.20.150 2 280 9.2E-46 T 28-03-2018 CP478_RS02660 17912a32ae25443c75a0c97ba2e861ea 280 Pfam PF01261 Xylose isomerase-like TIM barrel 23 229 1.4E-14 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 Gene3D G3DSA:1.10.10.10 2 76 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 SMART SM00346 16 103 1.7E-29 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 SUPERFAMILY SSF46785 16 85 1.02E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 Gene3D G3DSA:3.30.450.40 85 243 6.9E-30 T 28-03-2018 IPR029016 GAF domain-like CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 Pfam PF01614 Bacterial transcriptional regulator 131 245 1.3E-25 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 Pfam PF09339 IclR helix-turn-helix domain 19 68 5.1E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS09665 020ea0172f963a24e5b5f4a207838734 248 SUPERFAMILY SSF55781 80 242 2.42E-29 T 28-03-2018 IPR029016 GAF domain-like CP478_RS06950 a6584f8e31b33bb3916216dcf812812f 244 SUPERFAMILY SSF89392 45 241 9.81E-50 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CP478_RS06950 a6584f8e31b33bb3916216dcf812812f 244 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 23 238 9.0E-116 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS06950 a6584f8e31b33bb3916216dcf812812f 244 Pfam PF07161 LppX_LprAFG lipoprotein 45 239 5.5E-67 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Gene3D G3DSA:3.30.413.10 171 282 4.4E-20 T 28-03-2018 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 100 160 2.5E-13 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 346 408 4.7E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 420 557 2.4E-10 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 321 4.6E-35 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 SUPERFAMILY SSF56014 170 328 1.44E-42 T 28-03-2018 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 PRINTS PR00397 Sirohaem Fe-binding site signature 469 487 8.1E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 PRINTS PR00397 Sirohaem Fe-binding site signature 420 438 8.1E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 SUPERFAMILY SSF56014 416 563 3.79E-37 T 28-03-2018 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 SUPERFAMILY SSF55124 19 169 1.08E-41 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Gene3D G3DSA:3.30.413.10 418 563 4.7E-29 T 28-03-2018 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 469 485 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 SUPERFAMILY SSF55124 336 412 1.14E-17 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS13040 27d9d8c5dd6a35abc9728658a1f601c7 563 Gene3D G3DSA:3.90.480.10 283 415 1.3E-25 T 28-03-2018 CP478_RS19190 cca8d36788a946e1a419aa2f46bfa6c8 278 SUPERFAMILY SSF51556 7 273 5.35E-60 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS19190 cca8d36788a946e1a419aa2f46bfa6c8 278 Pfam PF04909 Amidohydrolase 69 270 6.3E-38 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS19190 cca8d36788a946e1a419aa2f46bfa6c8 278 Gene3D G3DSA:3.20.20.140 3 273 1.1E-43 T 28-03-2018 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 SMART SM00475 78 359 2.1E-113 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 269 353 1.1E-18 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 Gene3D G3DSA:1.10.150.20 279 359 1.0E-18 T 28-03-2018 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 SMART SM00279 267 302 1.0E-9 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 SUPERFAMILY SSF47807 270 385 1.64E-19 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 Gene3D G3DSA:3.40.50.1010 78 278 1.5E-54 T 28-03-2018 IPR029060 PIN domain-like CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 80 260 2.7E-48 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CP478_RS11385 d0e35f30bffee1de23ecbdedc0dcac86 393 SUPERFAMILY SSF88723 78 238 2.8E-37 T 28-03-2018 IPR029060 PIN domain-like CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 8.7E-19 T 28-03-2018 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 203 218 8.7E-19 T 28-03-2018 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 344 8.7E-19 T 28-03-2018 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 54 76 8.7E-19 T 28-03-2018 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 Gene3D G3DSA:3.50.50.60 51 401 2.6E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 Pfam PF01494 FAD binding domain 53 393 7.3E-78 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 SUPERFAMILY SSF51905 54 224 2.13E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09550 100b5bc3a9691a879da3b2262f5a9c48 460 SUPERFAMILY SSF51905 316 406 2.13E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 SUPERFAMILY SSF56719 8 500 5.23E-169 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 15 818 0.0 T 28-03-2018 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Gene3D G3DSA:1.10.268.10 356 498 3.5E-46 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 565 608 1.5E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 773 816 5.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 515 562 4.4E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 669 717 1.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 622 666 2.0E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 722 769 1.4E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Gene3D G3DSA:3.30.1360.40 247 344 7.7E-32 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 10 820 23.661 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Gene3D G3DSA:2.120.10.90 508 820 2.4E-115 T 28-03-2018 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 SMART SM00434 18 476 3.9E-273 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 39 483 4.8E-147 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 Gene3D G3DSA:3.90.199.10 41 223 9.5E-81 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CP478_RS00030 0b1cc19ff0dc74bde5387e15081d56af 838 SUPERFAMILY SSF101904 510 826 3.92E-100 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 SUPERFAMILY SSF51905 471 527 4.4E-80 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 SUPERFAMILY SSF51905 1 290 4.4E-80 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 PIRSF PIRSF000137 1 528 9.9E-145 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 Pfam PF00732 GMC oxidoreductase 6 298 9.9E-103 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 Pfam PF05199 GMC oxidoreductase 383 522 1.5E-37 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 SUPERFAMILY SSF54373 292 472 2.06E-36 T 28-03-2018 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 Gene3D G3DSA:4.10.450.10 36 103 1.7E-31 T 28-03-2018 CP478_RS06995 2702d6505bb0ec99647d87d3352d480f 528 Gene3D G3DSA:3.30.560.10 104 484 1.9E-91 T 28-03-2018 CP478_RS17315 3546f91bbab3915fe4ce233bed637d41 423 Pfam PF01882 Protein of unknown function DUF58 188 270 9.1E-17 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CP478_RS17315 3546f91bbab3915fe4ce233bed637d41 423 Gene3D G3DSA:3.40.50.410 200 406 1.8E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS07695 59305aa7ac8ccc9927ffd2a889ac9522 274 SUPERFAMILY SSF53335 19 170 2.09E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS07695 59305aa7ac8ccc9927ffd2a889ac9522 274 Gene3D G3DSA:3.40.50.150 39 274 1.8E-30 T 28-03-2018 CP478_RS07695 59305aa7ac8ccc9927ffd2a889ac9522 274 Pfam PF08241 Methyltransferase domain 54 147 9.4E-20 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 260 271 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 617 8.5E-27 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 SUPERFAMILY SSF56801 23 649 5.89E-174 T 28-03-2018 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 26 79 3.4E-22 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Gene3D G3DSA:2.30.38.10 430 523 3.5E-14 T 28-03-2018 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 7 651 50.413 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 21 649 9.0E-292 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Gene3D G3DSA:3.40.50.980 266 429 4.7E-37 T 28-03-2018 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Gene3D G3DSA:3.30.300.30 524 636 1.5E-30 T 28-03-2018 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Pfam PF00501 AMP-binding enzyme 85 530 3.7E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS20025 9ff54a886ce96795a0ccfee924ba21bb 651 Gene3D G3DSA:3.40.50.980 72 265 1.4E-48 T 28-03-2018 CP478_RS10065 49aaad6d55cd5c049ff3e9a2d81a46ba 211 PIRSF PIRSF009467 1 211 7.4E-43 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CP478_RS10065 49aaad6d55cd5c049ff3e9a2d81a46ba 211 Pfam PF01730 UreF 38 171 6.6E-13 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CP478_RS10065 49aaad6d55cd5c049ff3e9a2d81a46ba 211 Hamap MF_01385 Urease accessory protein UreF [ureF]. 3 211 16.901 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 PIRSF PIRSF000429 1 408 2.0E-53 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 SUPERFAMILY SSF53901 5 242 1.79E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 Pfam PF00108 Thiolase, N-terminal domain 7 235 6.9E-9 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 Pfam PF02803 Thiolase, C-terminal domain 287 379 1.1E-7 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 Gene3D G3DSA:3.40.47.10 2 237 3.0E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 SUPERFAMILY SSF53901 273 396 3.15E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS04985 5c9f527c287a73fc156e22443209d842 412 Gene3D G3DSA:3.40.47.10 238 407 9.2E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 SUPERFAMILY SSF55124 517 654 3.2E-21 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Gene3D G3DSA:3.30.413.10 644 817 1.8E-38 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Gene3D G3DSA:3.50.50.60 266 332 1.8E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00397 Sirohaem Fe-binding site signature 649 667 1.6E-5 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00397 Sirohaem Fe-binding site signature 692 710 1.6E-5 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Gene3D G3DSA:3.50.50.60 113 262 1.9E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 SUPERFAMILY SSF51905 15 206 9.15E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Gene3D G3DSA:3.90.480.10 454 641 6.9E-19 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Gene3D G3DSA:3.50.50.60 4 112 9.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 2.6E-6 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 2.6E-6 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 2.6E-6 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 SUPERFAMILY SSF56014 646 818 2.09E-50 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 5.2E-16 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 5.2E-16 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 5.2E-16 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 5.2E-16 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 5.2E-16 T 28-03-2018 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 SUPERFAMILY SSF51905 165 328 5.76E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Pfam PF04324 BFD-like [2Fe-2S] binding domain 441 488 2.3E-9 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 302 1.0E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 16 812 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 573 633 1.7E-9 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 692 708 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 645 782 5.8E-20 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CP478_RS01360 75371ac68b885fca5ba94f797e3e1395 853 PIRSF PIRSF037149 8 846 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 52 1.5E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 SUPERFAMILY SSF47741 85 153 2.49E-30 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 Gene3D G3DSA:3.10.20.30 1 74 8.5E-24 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 Gene3D G3DSA:1.10.150.120 75 159 5.8E-33 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 SUPERFAMILY SSF54292 1 78 3.8E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS01995 61e71b9485920a5f70efab6a841c4148 159 Pfam PF01799 [2Fe-2S] binding domain 73 146 4.3E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 4 357 42.781 T 28-03-2018 IPR023763 DNA integrity scanning protein, DisA CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 SUPERFAMILY SSF47781 281 348 8.53E-11 T 28-03-2018 IPR010994 RuvA domain 2-like CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 SUPERFAMILY SSF143597 17 141 3.53E-27 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Gene3D G3DSA:1.10.150.20 293 355 3.5E-8 T 28-03-2018 CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Pfam PF10635 DisA bacterial checkpoint controller linker region 141 284 3.0E-47 T 28-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Pfam PF12826 Helix-hairpin-helix motif 299 347 2.0E-6 T 28-03-2018 CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Gene3D G3DSA:3.40.1700.10 6 141 2.7E-27 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CP478_RS19595 89208470348e48ae5ef13cad9dc02497 358 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 24 137 1.8E-24 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CP478_RS07035 24f2b486f97bbc877bf80a70fea2fbd5 161 Gene3D G3DSA:1.10.10.10 1 142 2.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07035 24f2b486f97bbc877bf80a70fea2fbd5 161 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.3E-40 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CP478_RS07035 24f2b486f97bbc877bf80a70fea2fbd5 161 SUPERFAMILY SSF46785 2 132 3.52E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS07035 24f2b486f97bbc877bf80a70fea2fbd5 161 Pfam PF02082 Transcriptional regulator 1 83 3.4E-25 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CP478_RS07035 24f2b486f97bbc877bf80a70fea2fbd5 161 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 6.8E-6 T 28-03-2018 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.8E-6 T 28-03-2018 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 SUPERFAMILY SSF56425 243 389 2.54E-30 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 SUPERFAMILY SSF51905 393 451 3.76E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 SUPERFAMILY SSF51905 4 270 3.76E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 415 2.6E-5 T 28-03-2018 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.6E-5 T 28-03-2018 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 PIRSF PIRSF000171 1 594 9.4E-36 T 28-03-2018 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 Gene3D G3DSA:1.20.58.100 468 574 8.8E-28 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 Pfam PF00890 FAD binding domain 10 429 5.0E-87 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 Gene3D G3DSA:3.50.50.60 2 467 4.4E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 SUPERFAMILY SSF46977 481 642 8.37E-40 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS01340 b01226d5e2021676644c41fcb595cbe0 646 Pfam PF02910 Fumarate reductase flavoprotein C-term 488 586 7.6E-21 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 Gene3D G3DSA:1.20.1560.10 8 323 6.7E-19 T 28-03-2018 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 SMART SM00382 367 563 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 SUPERFAMILY SSF52540 360 550 5.06E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 Gene3D G3DSA:3.40.50.300 353 557 3.7E-40 T 28-03-2018 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 SUPERFAMILY SSF90123 20 322 1.83E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 Pfam PF00005 ABC transporter 361 506 8.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08860 0e5ea65d9e1ccd6ab73c74ac0656e75f 576 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 18 541 1.5E-169 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CP478_RS02680 a72acf192d13d4ab3d249b0a5fe8339d 33 SMART SM01155 1 33 2.8E-8 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS02680 a72acf192d13d4ab3d249b0a5fe8339d 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 4.1E-12 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 Gene3D G3DSA:2.160.10.10 235 354 1.9E-20 T 28-03-2018 CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 286 0.0012 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 305 335 0.001 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 SUPERFAMILY SSF53448 8 308 1.59E-71 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 Gene3D G3DSA:3.90.550.10 1 234 4.1E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS17900 8d9658b6d89e8f9e062010f8e6d2765d 359 Pfam PF00483 Nucleotidyl transferase 8 235 8.6E-43 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CP478_RS04430 d0e6a706350b06ec28025c8b4a734096 140 Gene3D G3DSA:3.40.30.10 101 140 3.5E-4 T 28-03-2018 CP478_RS04430 d0e6a706350b06ec28025c8b4a734096 140 Pfam PF00085 Thioredoxin 53 135 5.6E-8 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CP478_RS04430 d0e6a706350b06ec28025c8b4a734096 140 Gene3D G3DSA:3.40.30.10 41 100 5.5E-11 T 28-03-2018 CP478_RS04430 d0e6a706350b06ec28025c8b4a734096 140 SUPERFAMILY SSF52833 49 139 1.44E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 28 707 41.206 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 SUPERFAMILY SSF81653 131 224 2.09E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 SUPERFAMILY SSF81665 225 316 1.18E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 SUPERFAMILY SSF81665 50 123 1.18E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Gene3D G3DSA:2.70.150.10 35 225 3.2E-27 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Pfam PF00122 E1-E2 ATPase 126 301 1.2E-35 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Gene3D G3DSA:3.40.1110.10 333 469 1.9E-17 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 SUPERFAMILY SSF56784 319 340 2.06E-35 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 SUPERFAMILY SSF56784 380 592 2.06E-35 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Gene3D G3DSA:3.40.50.1000 470 599 1.6E-31 T 28-03-2018 IPR023214 HAD-like domain CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 25 703 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 1.0E-23 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 490 500 1.0E-23 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 562 1.0E-23 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 578 1.0E-23 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 171 185 1.0E-23 T 28-03-2018 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 463 626 4.8E-38 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 358 3.8E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS05650 5a53a89573a39c6285d936470db80c5e 709 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 557 3.4E-31 T 28-03-2018 CP478_RS14745 d34eb692c20a69c574632a800c719691 405 Gene3D G3DSA:3.40.50.150 202 404 1.0E-29 T 28-03-2018 CP478_RS14745 d34eb692c20a69c574632a800c719691 405 SUPERFAMILY SSF50249 18 68 6.28E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS14745 d34eb692c20a69c574632a800c719691 405 Gene3D G3DSA:2.40.50.140 6 80 5.5E-19 T 28-03-2018 CP478_RS14745 d34eb692c20a69c574632a800c719691 405 Pfam PF01938 TRAM domain 15 60 1.2E-5 T 28-03-2018 IPR002792 TRAM domain CP478_RS14745 d34eb692c20a69c574632a800c719691 405 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 332 404 1.3E-7 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CP478_RS14745 d34eb692c20a69c574632a800c719691 405 SUPERFAMILY SSF53335 69 403 1.58E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 SUPERFAMILY SSF56059 345 489 3.59E-57 T 28-03-2018 CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 SUPERFAMILY SSF56059 59 238 3.59E-57 T 28-03-2018 CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 Pfam PF04174 A circularly permuted ATPgrasp 100 431 4.3E-164 T 28-03-2018 IPR007302 Circularly permuted ATPgrasp domain CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 Gene3D G3DSA:3.30.470.20 23 238 0.3 T 28-03-2018 CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 Gene3D G3DSA:3.30.470.20 261 519 2.3E-5 T 28-03-2018 CP478_RS13165 2329c1ecb3ecce1ba663e16f2838458e 551 PIRSF PIRSF005522 23 503 7.4E-221 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 Gene3D G3DSA:3.30.1330.60 164 326 2.4E-33 T 28-03-2018 IPR006665 OmpA-like domain CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 Pfam PF04972 BON domain 147 195 4.5E-6 T 28-03-2018 IPR007055 BON domain CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 Pfam PF00691 OmpA family 225 319 1.6E-20 T 28-03-2018 IPR006665 OmpA-like domain CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 30 54 5.5E-7 T 28-03-2018 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 288 307 5.5E-7 T 28-03-2018 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 270 287 5.5E-7 T 28-03-2018 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 308 326 5.5E-7 T 28-03-2018 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 ProSitePatterns PS01068 OmpA-like domain. 257 301 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 SUPERFAMILY SSF103088 219 325 4.45E-34 T 28-03-2018 IPR006665 OmpA-like domain CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01021 OMPA domain signature 255 270 8.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01021 OMPA domain signature 225 247 8.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CP478_RS04905 763f16d9c3da601e23e0772309ca5aa3 326 PRINTS PR01021 OMPA domain signature 270 286 8.4E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CP478_RS14085 80b73de871f6b61264db0256ca4876fd 314 SMART SM00460 188 262 1.3E-18 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14085 80b73de871f6b61264db0256ca4876fd 314 SUPERFAMILY SSF54001 82 310 6.13E-39 T 28-03-2018 CP478_RS14085 80b73de871f6b61264db0256ca4876fd 314 Pfam PF01841 Transglutaminase-like superfamily 158 260 1.2E-15 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14085 80b73de871f6b61264db0256ca4876fd 314 Gene3D G3DSA:3.90.260.10 165 274 6.6E-5 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14085 80b73de871f6b61264db0256ca4876fd 314 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 17 96 1.0E-22 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CP478_RS19220 1940c29046f2e1e0e422bc1360e06a9a 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 262 2.0E-56 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS19220 1940c29046f2e1e0e422bc1360e06a9a 263 SUPERFAMILY SSF52096 6 263 5.9E-78 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS19220 1940c29046f2e1e0e422bc1360e06a9a 263 Gene3D G3DSA:1.10.12.10 210 263 6.8E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS19220 1940c29046f2e1e0e422bc1360e06a9a 263 Gene3D G3DSA:3.90.226.10 1 209 1.3E-62 T 28-03-2018 CP478_RS04150 fb1d2aa2f4d1eb158b3c03793ea69272 181 SUPERFAMILY SSF54427 7 134 2.67E-21 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS04150 fb1d2aa2f4d1eb158b3c03793ea69272 181 Gene3D G3DSA:3.10.450.50 4 140 2.5E-16 T 28-03-2018 CP478_RS12455 1df6872b16a82c9fb5c979f87eb799e4 246 SUPERFAMILY SSF53167 39 147 1.25E-15 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS12455 1df6872b16a82c9fb5c979f87eb799e4 246 Gene3D G3DSA:3.40.50.1580 24 205 7.7E-19 T 28-03-2018 CP478_RS12455 1df6872b16a82c9fb5c979f87eb799e4 246 Pfam PF01048 Phosphorylase superfamily 40 148 6.4E-14 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 SMART SM00220 151 393 6.7E-27 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Pfam PF16918 Protein kinase G tetratricopeptide repeat 409 748 4.3E-152 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 272 284 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Pfam PF00069 Protein kinase domain 151 343 1.9E-31 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 SUPERFAMILY SSF48452 510 685 8.26E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 SUPERFAMILY SSF56112 131 402 2.34E-45 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Gene3D G3DSA:1.25.40.10 407 587 2.8E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Gene3D G3DSA:1.10.510.10 234 405 1.4E-31 T 28-03-2018 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Pfam PF16919 Protein kinase G rubredoxin domain 12 150 4.9E-62 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS02185 2a15568b0eb8539ee69c1cff477d468b 750 Gene3D G3DSA:3.30.200.20 140 233 1.4E-13 T 28-03-2018 CP478_RS12280 d9a7ec74c78c969071b38595a2a85de8 272 Pfam PF00144 Beta-lactamase 13 255 4.8E-34 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS12280 d9a7ec74c78c969071b38595a2a85de8 272 Gene3D G3DSA:3.40.710.10 2 272 3.5E-53 T 28-03-2018 CP478_RS12280 d9a7ec74c78c969071b38595a2a85de8 272 SUPERFAMILY SSF56601 10 267 2.73E-52 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 SUPERFAMILY SSF56801 5 573 8.24E-97 T 28-03-2018 CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 Gene3D G3DSA:3.40.50.980 178 351 4.4E-27 T 28-03-2018 CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 Gene3D G3DSA:2.30.38.10 379 461 1.2E-19 T 28-03-2018 CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 Pfam PF00501 AMP-binding enzyme 11 468 2.1E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 Gene3D G3DSA:3.30.300.30 462 571 2.5E-13 T 28-03-2018 CP478_RS16115 4de0fb8f6c4fcf889e2d616faa4cbf8b 582 Gene3D G3DSA:3.40.50.980 1 177 1.8E-29 T 28-03-2018 CP478_RS15745 f8bef0bed6a9e8fdaaaca8751223168b 306 Pfam PF01148 Cytidylyltransferase family 37 304 2.2E-60 T 28-03-2018 CP478_RS15745 f8bef0bed6a9e8fdaaaca8751223168b 306 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 263 289 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CP478_RS20220 73898bd9aa11561350911839d4192d96 321 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 5 321 53.411 T 28-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CP478_RS20220 73898bd9aa11561350911839d4192d96 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 18 320 5.3E-111 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent CP478_RS20220 73898bd9aa11561350911839d4192d96 321 SUPERFAMILY SSF53335 38 206 2.82E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20220 73898bd9aa11561350911839d4192d96 321 SUPERFAMILY SSF53335 256 312 2.82E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20220 73898bd9aa11561350911839d4192d96 321 PIRSF PIRSF018005 2 321 2.0E-141 T 28-03-2018 IPR017804 Methyltransferase EgtD-like CP478_RS20220 73898bd9aa11561350911839d4192d96 321 Gene3D G3DSA:3.40.50.150 13 320 1.7E-20 T 28-03-2018 CP478_RS20220 73898bd9aa11561350911839d4192d96 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 318 4.1E-112 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 SUPERFAMILY SSF52304 6 145 2.09E-53 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 Pfam PF01220 Dehydroquinase class II 6 141 4.4E-53 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 PIRSF PIRSF001399 2 147 5.5E-55 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 6 143 2.0E-73 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 Gene3D G3DSA:3.40.50.9100 2 147 1.1E-57 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 9 26 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 62.155 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS13905 60a2951e2823d786f14ebc135a192f16 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 144 7.1E-62 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CP478_RS20510 a36fddcb968e6457ee086302867051e1 199 SUPERFAMILY SSF159275 11 198 3.92E-56 T 28-03-2018 CP478_RS20510 a36fddcb968e6457ee086302867051e1 199 Pfam PF06475 Putative glycolipid-binding 16 198 3.8E-56 T 28-03-2018 IPR009467 Putative glycolipid-binding protein CP478_RS18940 75186ec217065a1a8c042703fc188460 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.457 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18940 75186ec217065a1a8c042703fc188460 37 SUPERFAMILY SSF57840 2 37 8.11E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18940 75186ec217065a1a8c042703fc188460 37 Pfam PF00444 Ribosomal protein L36 2 37 8.3E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18940 75186ec217065a1a8c042703fc188460 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 3.0E-9 T 28-03-2018 CP478_RS18940 75186ec217065a1a8c042703fc188460 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18940 75186ec217065a1a8c042703fc188460 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 9.8E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS19965 77c8749ab5f8da5c065aa2ac160bb96b 266 Pfam PF00482 Type II secretion system (T2SS), protein F 97 219 3.1E-9 T 28-03-2018 IPR018076 Type II secretion system F domain CP478_RS19965 77c8749ab5f8da5c065aa2ac160bb96b 266 Gene3D G3DSA:1.20.1560.10 41 257 8.5E-4 T 28-03-2018 CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 ProSitePatterns PS00892 HIT domain signature. 79 97 - T 28-03-2018 IPR019808 Histidine triad, conserved site CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 Pfam PF01230 HIT domain 10 100 1.3E-23 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 PRINTS PR00332 Histidine triad family signature 24 42 2.9E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 PRINTS PR00332 Histidine triad family signature 3 19 2.9E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 PRINTS PR00332 Histidine triad family signature 86 96 2.9E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 SUPERFAMILY SSF54197 2 131 4.18E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS04135 062b0f1be0810b85356e081ae896dd53 133 Gene3D G3DSA:3.30.428.10 2 133 2.5E-26 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 SUPERFAMILY SSF51395 1 351 3.1E-98 T 28-03-2018 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 288 308 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 332 47.851 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 353 5.8E-163 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 84 103 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 Pfam PF01180 Dihydroorotate dehydrogenase 49 336 2.0E-99 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CP478_RS11635 103eafca90234ac53ea6b4aa4610fdec 357 Gene3D G3DSA:3.20.20.70 1 357 2.0E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 SUPERFAMILY SSF51905 2 333 5.18E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Gene3D G3DSA:3.50.50.60 2 46 2.8E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.3E-63 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 324 2.7E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PIRSF PIRSF000350 1 457 6.5E-87 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Gene3D G3DSA:3.50.50.60 117 248 2.7E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Gene3D G3DSA:3.50.50.60 267 360 9.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 463 4.5E-161 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 452 3.3E-34 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.5E-34 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 3.5E-34 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 3.5E-34 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 3.5E-34 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 3.5E-34 T 28-03-2018 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 SUPERFAMILY SSF55424 341 463 5.33E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Gene3D G3DSA:3.30.390.30 361 457 7.5E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS02465 caac6d0811e964165c1edca22cecc356 464 Gene3D G3DSA:1.10.287.990 47 103 3.5E-16 T 28-03-2018 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Pfam PF01580 FtsK/SpoIIIE family 721 967 5.9E-76 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Pfam PF01580 FtsK/SpoIIIE family 388 515 1.1E-22 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Pfam PF01580 FtsK/SpoIIIE family 1009 1106 5.2E-8 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SUPERFAMILY SSF52540 705 990 2.75E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SUPERFAMILY SSF52540 385 646 3.43E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 688 1231 4.6E-229 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SUPERFAMILY SSF52540 983 1165 1.97E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Gene3D G3DSA:3.40.50.300 991 1186 5.1E-6 T 28-03-2018 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Gene3D G3DSA:3.40.50.300 365 617 4.6E-19 T 28-03-2018 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 Gene3D G3DSA:3.40.50.300 719 977 3.6E-17 T 28-03-2018 CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 15 645 1.6E-250 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SMART SM00382 757 987 0.23 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SMART SM00382 423 597 3.3 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS18865 b3e5087979903d9f813b37298669c858 1236 SMART SM00382 1027 1186 0.81 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS17565 4e7daaaa5194b9cb72a8cabcd117e52d 101 SUPERFAMILY SSF46767 6 82 8.11E-16 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CP478_RS17565 4e7daaaa5194b9cb72a8cabcd117e52d 101 Gene3D G3DSA:1.10.10.10 4 98 2.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17565 4e7daaaa5194b9cb72a8cabcd117e52d 101 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 12 82 8.0E-18 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 Pfam PF04851 Type III restriction enzyme, res subunit 174 320 5.0E-14 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 Gene3D G3DSA:3.40.50.300 166 348 5.1E-27 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 346 530 8.2E-42 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 SMART SM00487 171 346 6.9E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 Pfam PF13625 Helicase conserved C-terminal domain 1 127 8.2E-45 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 SUPERFAMILY SSF52540 134 338 2.57E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 SUPERFAMILY SSF52540 283 353 7.98E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 SUPERFAMILY SSF52540 386 503 7.98E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 Gene3D G3DSA:3.40.50.300 373 508 3.2E-16 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 SMART SM00490 416 493 2.3E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 468 493 1.6E-34 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 284 304 1.6E-34 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 349 371 1.6E-34 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 184 206 1.6E-34 T 28-03-2018 CP478_RS04700 2ffc59ce29bbca6b4de07d69d4d05fa8 542 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 449 467 1.6E-34 T 28-03-2018 CP478_RS03215 28d7104312d8dda6734c246632e82a6b 156 SUPERFAMILY SSF47384 104 149 9.61E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS03215 28d7104312d8dda6734c246632e82a6b 156 SMART SM00304 64 120 1.6E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS03215 28d7104312d8dda6734c246632e82a6b 156 SUPERFAMILY SSF158472 66 117 6.54E-6 T 28-03-2018 CP478_RS03215 28d7104312d8dda6734c246632e82a6b 156 Pfam PF00672 HAMP domain 64 117 3.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS03215 28d7104312d8dda6734c246632e82a6b 156 Gene3D G3DSA:1.10.287.130 111 150 9.6E-9 T 28-03-2018 CP478_RS16235 c76cb7ea83cbd2a5a0f8c58efd367ba1 376 SUPERFAMILY SSF53474 95 371 9.32E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16235 c76cb7ea83cbd2a5a0f8c58efd367ba1 376 Gene3D G3DSA:3.40.50.1820 56 376 6.5E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16235 c76cb7ea83cbd2a5a0f8c58efd367ba1 376 Pfam PF07859 alpha/beta hydrolase fold 137 349 4.0E-72 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS10895 264bda9eabe8859e72cb35835ab0ec61 258 SUPERFAMILY SSF51621 3 233 4.08E-44 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS10895 264bda9eabe8859e72cb35835ab0ec61 258 Gene3D G3DSA:3.20.20.60 1 251 1.9E-42 T 28-03-2018 CP478_RS10895 264bda9eabe8859e72cb35835ab0ec61 258 Pfam PF13714 Phosphoenolpyruvate phosphomutase 3 229 2.0E-60 T 28-03-2018 CP478_RS19620 2c585bc9268e33c4c00707be94acf4c5 257 Gene3D G3DSA:3.40.50.1820 4 257 8.8E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19620 2c585bc9268e33c4c00707be94acf4c5 257 Pfam PF12697 Alpha/beta hydrolase family 19 246 6.3E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19620 2c585bc9268e33c4c00707be94acf4c5 257 SUPERFAMILY SSF53474 10 252 1.54E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 SUPERFAMILY SSF88659 100 156 1.53E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Gene3D G3DSA:3.10.450.50 148 294 3.4E-18 T 28-03-2018 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 155 6.7E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Pfam PF12680 SnoaL-like domain 175 280 6.1E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 SUPERFAMILY SSF88946 6 82 8.63E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Gene3D G3DSA:1.10.1740.10 3 68 2.5E-13 T 28-03-2018 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Pfam PF04542 Sigma-70 region 2 6 68 9.0E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Gene3D G3DSA:1.10.10.10 69 147 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 SUPERFAMILY SSF54427 168 291 1.37E-17 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS18230 08f1288bf81b9d60bb4469e9a63c3f37 312 Pfam PF08281 Sigma-70, region 4 107 155 6.9E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 Gene3D G3DSA:3.40.1280.10 96 257 3.9E-46 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 Pfam PF00588 SpoU rRNA Methylase family 109 251 5.3E-37 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 SMART SM00967 28 98 2.1E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 28 93 8.5E-8 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 SUPERFAMILY SSF75217 102 257 3.53E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 SUPERFAMILY SSF55315 5 95 4.71E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS09000 cc4ff5b0c21aa4ffaec69aa6f2be7c48 260 Gene3D G3DSA:3.30.1330.30 2 95 8.5E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 Gene3D G3DSA:3.30.360.10 141 325 7.7E-63 T 28-03-2018 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 342 35.133 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 328 1.3E-45 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 SUPERFAMILY SSF55347 129 329 6.79E-58 T 28-03-2018 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 SUPERFAMILY SSF51735 3 156 3.73E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 343 2.7E-151 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 243 257 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 114 6.8E-29 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 PIRSF PIRSF000148 2 345 3.9E-107 T 28-03-2018 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 SMART SM00859 4 119 1.8E-37 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CP478_RS20260 873fd3662d826afeef4330112e31ad8b 345 Gene3D G3DSA:3.40.50.720 2 140 4.3E-33 T 28-03-2018 CP478_RS18805 3e0dc52241cfa21625d3e42eab89c515 284 Pfam PF14494 Domain of unknown function (DUF4436) 24 275 6.4E-101 T 28-03-2018 IPR027948 Protein of unknown function (DUF4436) CP478_RS15000 92faeb9069dee1a64e2929aa87710811 57 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 37 57 5.4E-11 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 38 401 30.915 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 231 392 3.0E-41 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 Gene3D G3DSA:3.40.50.2000 218 385 2.9E-33 T 28-03-2018 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 38 185 4.3E-39 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 34 395 2.2E-94 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 SUPERFAMILY SSF53756 38 400 1.55E-94 T 28-03-2018 CP478_RS11715 62a86329dd83067faa1670073e8fe848 410 Gene3D G3DSA:3.40.50.2000 31 217 3.7E-32 T 28-03-2018 CP478_RS00295 69cbf52db2ddfdab4e3b6684e93e0e5f 164 SUPERFAMILY SSF50249 6 164 4.41E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS00295 69cbf52db2ddfdab4e3b6684e93e0e5f 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 164 1.3E-40 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CP478_RS00295 69cbf52db2ddfdab4e3b6684e93e0e5f 164 Gene3D G3DSA:2.40.50.140 2 119 2.7E-41 T 28-03-2018 CP478_RS00295 69cbf52db2ddfdab4e3b6684e93e0e5f 164 Pfam PF00436 Single-strand binding protein family 6 106 1.4E-30 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CP478_RS00295 69cbf52db2ddfdab4e3b6684e93e0e5f 164 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 32.004 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CP478_RS21260 4bf4bf10a49e2fa425038d9038c4ad35 95 ProDom PD065399 ESAT-6-LIKE ESAT-6 ORF3890C LIKE 1 95 2.0E-40 T 28-03-2018 IPR020167 ESAT-6-like protein EsxC CP478_RS21260 4bf4bf10a49e2fa425038d9038c4ad35 95 SUPERFAMILY SSF140453 3 95 4.45E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21260 4bf4bf10a49e2fa425038d9038c4ad35 95 Gene3D G3DSA:1.10.287.1060 1 95 1.6E-11 T 28-03-2018 CP478_RS21260 4bf4bf10a49e2fa425038d9038c4ad35 95 Pfam PF06013 Proteins of 100 residues with WXG 4 79 6.7E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS08315 97a8492b5729b897bd8be01509627963 336 SUPERFAMILY SSF53448 7 223 7.19E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08315 97a8492b5729b897bd8be01509627963 336 Pfam PF00535 Glycosyl transferase family 2 10 170 1.9E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS08315 97a8492b5729b897bd8be01509627963 336 Gene3D G3DSA:3.90.550.10 2 238 6.0E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 Gene3D G3DSA:3.10.180.10 138 261 9.7E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 SUPERFAMILY SSF54593 144 255 2.82E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 123 5.5E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 149 252 1.1E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 SUPERFAMILY SSF54593 9 128 2.55E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS03090 dfe9228fbbba3b0f58a9c94379e9aaed 261 Gene3D G3DSA:3.10.180.10 1 137 1.7E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS01170 22f7db6e94869d3ec7799c55d4a64c3f 337 SUPERFAMILY SSF54637 10 181 1.45E-29 T 28-03-2018 IPR029069 HotDog domain CP478_RS01170 22f7db6e94869d3ec7799c55d4a64c3f 337 Gene3D G3DSA:3.10.129.10 2 160 3.0E-18 T 28-03-2018 CP478_RS01170 22f7db6e94869d3ec7799c55d4a64c3f 337 Gene3D G3DSA:3.10.129.10 191 337 5.6E-19 T 28-03-2018 CP478_RS01170 22f7db6e94869d3ec7799c55d4a64c3f 337 PIRSF PIRSF021494 6 337 3.6E-162 T 28-03-2018 IPR016790 Thiol ester hydratase, Rv0216, predicted KEGG: 00630+4.2.1.148|KEGG: 00660+4.2.1.148|KEGG: 00720+4.2.1.148|MetaCyc: PWY-5741|MetaCyc: PWY-5744|MetaCyc: PWY-6728|MetaCyc: PWY-7854 CP478_RS01170 22f7db6e94869d3ec7799c55d4a64c3f 337 SUPERFAMILY SSF54637 188 335 1.17E-30 T 28-03-2018 IPR029069 HotDog domain CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 PIRSF PIRSF036426 141 403 2.5E-89 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 PIRSF PIRSF036426 3 154 8.6E-29 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 Gene3D G3DSA:3.40.1010.10 159 284 8.6E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 Pfam PF13241 Putative NAD(P)-binding 10 114 1.3E-21 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 Gene3D G3DSA:3.30.950.10 285 399 4.6E-34 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 SUPERFAMILY SSF51735 7 104 2.06E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 162 372 1.8E-45 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 Gene3D G3DSA:3.40.50.720 6 129 2.9E-12 T 28-03-2018 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 160 396 4.9E-80 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS15565 d5d6ac0ea7111ec4c040d52c988c0d54 405 SUPERFAMILY SSF53790 156 396 7.2E-70 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02925 324dfdcd4a5da38eecd56bc766b1a493 128 SUPERFAMILY SSF54593 9 115 2.48E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS02925 324dfdcd4a5da38eecd56bc766b1a493 128 Gene3D G3DSA:3.10.180.10 8 128 4.1E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS02925 324dfdcd4a5da38eecd56bc766b1a493 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 111 3.4E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS18165 9a4a6446f972de570c56e73db4479199 133 Gene3D G3DSA:3.40.140.10 2 131 1.1E-37 T 28-03-2018 CP478_RS18165 9a4a6446f972de570c56e73db4479199 133 SUPERFAMILY SSF53927 2 128 1.39E-39 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS18165 9a4a6446f972de570c56e73db4479199 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 103 1.2E-10 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CP478_RS18530 6e0b9ea9adaf2e174a4f2204c56e2ea0 130 Gene3D G3DSA:3.40.50.1010 1 130 9.7E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18530 6e0b9ea9adaf2e174a4f2204c56e2ea0 130 Pfam PF01850 PIN domain 4 120 5.9E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS18530 6e0b9ea9adaf2e174a4f2204c56e2ea0 130 SUPERFAMILY SSF88723 4 127 7.01E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18530 6e0b9ea9adaf2e174a4f2204c56e2ea0 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 126 13.636 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Gene3D G3DSA:4.10.320.10 109 159 4.8E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 168 390 3.9E-67 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Gene3D G3DSA:2.40.50.100 10 83 5.7E-14 T 28-03-2018 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Gene3D G3DSA:3.30.559.10 160 393 2.2E-66 T 28-03-2018 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 SUPERFAMILY SSF47005 114 158 1.44E-7 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Pfam PF02817 e3 binding domain 118 154 2.8E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 SUPERFAMILY SSF51230 8 92 6.02E-22 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 Pfam PF00364 Biotin-requiring enzyme 10 81 1.5E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS13645 3395affd191b19ab6c3be99cb14d8800 393 SUPERFAMILY SSF52777 166 392 4.89E-63 T 28-03-2018 CP478_RS20310 53749b5781e9557bdb5f67146430794b 147 PIRSF PIRSF017371 1 145 6.1E-88 T 28-03-2018 IPR014488 Uncharacterised conserved protein UCP017371 CP478_RS20310 53749b5781e9557bdb5f67146430794b 147 SUPERFAMILY SSF55961 4 128 9.43E-14 T 28-03-2018 CP478_RS20310 53749b5781e9557bdb5f67146430794b 147 Gene3D G3DSA:3.30.530.20 2 147 3.4E-16 T 28-03-2018 IPR023393 START-like domain CP478_RS20310 53749b5781e9557bdb5f67146430794b 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 7.1E-23 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS04270 0c52f1e06e444e18b3a630fcf3e33504 212 SMART SM00849 7 177 2.7E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04270 0c52f1e06e444e18b3a630fcf3e33504 212 Gene3D G3DSA:3.60.15.10 2 195 1.1E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04270 0c52f1e06e444e18b3a630fcf3e33504 212 SUPERFAMILY SSF56281 1 179 2.88E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04270 0c52f1e06e444e18b3a630fcf3e33504 212 Pfam PF13483 Beta-lactamase superfamily domain 2 177 1.1E-18 T 28-03-2018 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 SUPERFAMILY SSF52943 3 301 1.7E-80 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Pfam PF00231 ATP synthase 4 301 1.0E-89 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Gene3D G3DSA:1.10.287.80 3 60 8.5E-13 T 28-03-2018 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Gene3D G3DSA:1.10.287.80 251 296 4.5E-11 T 28-03-2018 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 301 2.2E-112 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 287 300 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.2E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 PRINTS PR00126 ATP synthase gamma subunit signature 279 300 1.2E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 PRINTS PR00126 ATP synthase gamma subunit signature 248 267 1.2E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 PRINTS PR00126 ATP synthase gamma subunit signature 180 197 1.2E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Gene3D G3DSA:3.40.1380.10 63 192 1.4E-41 T 28-03-2018 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 301 34.519 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07170 14a09ffd9357475b6994a808b7ce7db3 305 Gene3D G3DSA:1.10.287.80 193 250 1.6E-16 T 28-03-2018 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 SUPERFAMILY SSF48179 183 335 1.05E-47 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PIRSF PIRSF000114 2 336 4.9E-104 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 324 7.5E-48 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 Gene3D G3DSA:1.10.1040.10 184 331 4.6E-49 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 Gene3D G3DSA:3.40.50.720 1 183 3.2E-34 T 28-03-2018 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 12 29 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 62 89 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 137 157 2.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 164 9.6E-48 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 8 326 35.756 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS03015 dd3b7b349846bc828ad32e25bd687ddd 341 SUPERFAMILY SSF51735 8 184 6.7E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 SUPERFAMILY SSF51735 352 570 8.95E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 Gene3D G3DSA:3.40.50.720 336 608 2.2E-52 T 28-03-2018 CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 Gene3D G3DSA:3.40.50.720 1 250 2.5E-36 T 28-03-2018 CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 SUPERFAMILY SSF51735 1 265 4.15E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 477 493 3.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 503 522 3.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 354 371 3.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 428 439 3.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 353 537 8.6E-5 T 28-03-2018 CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 503 522 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 428 439 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 483 491 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 Pfam PF00106 short chain dehydrogenase 354 543 1.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18560 ff0d69aa7fa2c4e6b231c18bd9506796 650 Pfam PF07993 Male sterility protein 5 218 8.8E-29 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 Pfam PF01381 Helix-turn-helix 22 76 1.8E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 323 479 4.7E-65 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 PIRSF PIRSF019251 10 484 1.7E-175 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 Gene3D G3DSA:1.10.260.40 14 84 1.5E-15 T 28-03-2018 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 SMART SM00530 21 76 5.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 SUPERFAMILY SSF47413 16 79 7.24E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS06180 662c6e2a4178c2b15829d73e51f02d1f 486 Pfam PF06114 IrrE N-terminal-like domain 200 322 1.2E-19 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CP478_RS00450 5b74d1c0f61ddc23d4ba6551742f2081 152 Gene3D G3DSA:2.30.110.10 5 150 1.3E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS00450 5b74d1c0f61ddc23d4ba6551742f2081 152 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 20 143 1.2E-22 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CP478_RS00450 5b74d1c0f61ddc23d4ba6551742f2081 152 SUPERFAMILY SSF50475 15 144 8.68E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS03955 d591ff87c8918f0b5dc0be2a15bd9ea2 318 Gene3D G3DSA:3.40.50.150 8 296 6.6E-55 T 28-03-2018 CP478_RS03955 d591ff87c8918f0b5dc0be2a15bd9ea2 318 Pfam PF04072 Leucine carboxyl methyltransferase 24 208 1.0E-64 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS03955 d591ff87c8918f0b5dc0be2a15bd9ea2 318 SUPERFAMILY SSF53335 20 309 4.15E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03955 d591ff87c8918f0b5dc0be2a15bd9ea2 318 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 22 290 2.4E-90 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 Gene3D G3DSA:3.40.50.1820 16 286 3.6E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 SUPERFAMILY SSF53474 19 285 1.03E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 Pfam PF00561 alpha/beta hydrolase fold 40 272 3.7E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 4.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 4.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 4.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17385 01b1ad16a51483a2885bf0a211263f03 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09580 584cf50110cb905a58e2568b426f885c 179 SUPERFAMILY SSF53474 25 178 1.67E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09580 584cf50110cb905a58e2568b426f885c 179 SMART SM01110 8 178 3.7E-68 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS09580 584cf50110cb905a58e2568b426f885c 179 Gene3D G3DSA:3.40.50.1820 5 179 4.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09580 584cf50110cb905a58e2568b426f885c 179 Pfam PF01083 Cutinase 16 177 9.4E-37 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS17140 36f00a0a3d58410c0381f04f2b549d6b 332 Gene3D G3DSA:3.40.109.30 3 88 4.1E-12 T 28-03-2018 CP478_RS17140 36f00a0a3d58410c0381f04f2b549d6b 332 SUPERFAMILY SSF55469 6 66 4.94E-18 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17140 36f00a0a3d58410c0381f04f2b549d6b 332 SUPERFAMILY SSF55469 226 323 4.94E-18 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17140 36f00a0a3d58410c0381f04f2b549d6b 332 Gene3D G3DSA:3.40.109.10 101 324 8.8E-29 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 SMART SM00448 2 115 2.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 Gene3D G3DSA:3.40.50.2300 1 133 6.8E-32 T 28-03-2018 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 SMART SM00421 147 204 8.0E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 Gene3D G3DSA:1.10.10.10 134 209 6.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 SUPERFAMILY SSF52172 3 129 1.57E-28 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 SUPERFAMILY SSF46894 137 208 2.65E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 Pfam PF00072 Response regulator receiver domain 4 115 3.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS17150 3d0f887a68ae8ef13cb89884632428d7 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS07265 e31a182b2592794d5a343b5b7d22042f 304 SUPERFAMILY SSF52833 35 151 1.59E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS07265 e31a182b2592794d5a343b5b7d22042f 304 Gene3D G3DSA:3.40.30.10 36 239 1.4E-29 T 28-03-2018 CP478_RS07265 e31a182b2592794d5a343b5b7d22042f 304 Pfam PF14561 Tetratricopeptide repeat 233 304 9.8E-17 T 28-03-2018 CP478_RS07265 e31a182b2592794d5a343b5b7d22042f 304 Pfam PF00085 Thioredoxin 45 147 2.8E-10 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CP478_RS18745 490aa6b5db014afa9aadd4a6b6a952a9 176 Pfam PF00823 PPE family 4 158 1.2E-48 T 28-03-2018 IPR000030 PPE family CP478_RS18745 490aa6b5db014afa9aadd4a6b6a952a9 176 SUPERFAMILY SSF140459 2 172 8.63E-52 T 28-03-2018 CP478_RS18745 490aa6b5db014afa9aadd4a6b6a952a9 176 Gene3D G3DSA:1.10.287.1060 20 103 5.3E-8 T 28-03-2018 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 Hamap MF_00323 Ferrochelatase [hemH]. 2 299 31.294 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 TIGRFAM TIGR00109 hemH: ferrochelatase 5 290 8.4E-41 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 ProSitePatterns PS00534 Ferrochelatase signature. 167 187 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 Gene3D G3DSA:3.40.50.1400 151 281 4.3E-42 T 28-03-2018 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 SUPERFAMILY SSF53800 2 328 1.24E-82 T 28-03-2018 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 Gene3D G3DSA:3.40.50.1400 1 150 2.0E-29 T 28-03-2018 CP478_RS08135 247e4ea03a7dc14cd0d62579eb5423f7 344 Pfam PF00762 Ferrochelatase 4 296 6.1E-93 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CP478_RS20515 00743df956b7bbc449519343cdbca26e 239 Gene3D G3DSA:1.10.3720.10 3 210 2.9E-22 T 28-03-2018 CP478_RS20515 00743df956b7bbc449519343cdbca26e 239 SUPERFAMILY SSF161098 26 204 4.71E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20515 00743df956b7bbc449519343cdbca26e 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 204 5.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS04040 bf96b6b52c439de68f461dccc8006aa9 48 SUPERFAMILY SSF48179 2 46 1.36E-5 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS04040 bf96b6b52c439de68f461dccc8006aa9 48 Gene3D G3DSA:1.10.1040.10 1 48 6.3E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 SUPERFAMILY SSF52518 505 733 2.12E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 SUPERFAMILY SSF52518 85 500 1.15E-130 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 Gene3D G3DSA:3.40.50.970 84 504 7.5E-84 T 28-03-2018 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 33 922 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 Gene3D G3DSA:3.40.50.970 505 739 8.6E-68 T 28-03-2018 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 PIRSF PIRSF000156 25 923 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 SUPERFAMILY SSF52922 737 920 6.46E-51 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 165 331 4.3E-10 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS12195 b3eb51c39ec80ed219c0c382df6c0af2 930 Gene3D G3DSA:3.40.50.920 741 923 1.8E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS02300 a47848fcb0ab2fe30346fe0cbbfca1ca 240 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 226 237 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CP478_RS02300 a47848fcb0ab2fe30346fe0cbbfca1ca 240 SUPERFAMILY SSF49329 73 238 4.06E-46 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CP478_RS02300 a47848fcb0ab2fe30346fe0cbbfca1ca 240 Gene3D G3DSA:2.60.40.200 67 238 5.9E-29 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CP478_RS02300 a47848fcb0ab2fe30346fe0cbbfca1ca 240 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 81 237 2.6E-28 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Gene3D G3DSA:3.30.70.260 724 803 3.2E-9 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Gene3D G3DSA:3.30.70.260 611 693 2.0E-8 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Gene3D G3DSA:1.20.120.330 156 294 1.1E-4 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 SUPERFAMILY SSF81301 54 157 4.91E-17 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Pfam PF08335 GlnD PII-uridylyltransferase 177 288 1.4E-8 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 SUPERFAMILY SSF109604 397 504 4.71E-15 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Pfam PF01966 HD domain 431 536 3.6E-12 T 28-03-2018 IPR006674 HD domain CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Gene3D G3DSA:3.30.460.10 45 155 4.8E-10 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 PIRSF PIRSF006288 584 801 4.8E-29 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 PIRSF PIRSF006288 1 596 8.2E-170 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Gene3D G3DSA:1.10.3090.10 335 585 4.1E-36 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 808 65.396 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 16 586 5.2E-219 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 SMART SM00471 426 559 3.9E-9 T 28-03-2018 IPR003607 HD/PDEase domain CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 SUPERFAMILY SSF55021 729 794 2.08E-8 T 28-03-2018 CP478_RS15935 7e2906fb75eaabf70db17d096af2d2ca 808 SUPERFAMILY SSF81593 185 283 4.24E-5 T 28-03-2018 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 SUPERFAMILY SSF50249 204 341 3.34E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 SUPERFAMILY SSF56091 6 201 4.03E-41 T 28-03-2018 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 Gene3D G3DSA:2.40.50.140 201 347 4.2E-30 T 28-03-2018 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 Pfam PF01068 ATP dependent DNA ligase domain 11 201 3.2E-39 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 332 1.2E-14 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 Gene3D G3DSA:3.30.1490.70 145 200 8.2E-8 T 28-03-2018 CP478_RS20385 70d12ecaa771932061fe3bd89ad174dd 358 Gene3D G3DSA:3.30.470.30 1 144 2.6E-30 T 28-03-2018 CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 Gene3D G3DSA:1.20.58.220 111 212 7.2E-16 T 28-03-2018 CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 Gene3D G3DSA:1.20.58.220 1 110 5.7E-16 T 28-03-2018 CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 SUPERFAMILY SSF109755 2 212 4.92E-53 T 28-03-2018 CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 PIRSF PIRSF003107 1 212 2.8E-48 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 Pfam PF01895 PhoU domain 122 204 3.3E-11 T 28-03-2018 IPR026022 PhoU domain CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 Pfam PF01895 PhoU domain 17 103 4.5E-12 T 28-03-2018 IPR026022 PhoU domain CP478_RS04455 a42622b4fc86ef3dffc45c5c21ccfdd8 213 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.8E-61 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 Gene3D G3DSA:2.40.100.10 86 210 3.7E-42 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 SMART SM00796 7 199 8.3E-75 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 Gene3D G3DSA:3.30.1360.40 4 82 2.1E-16 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 8 199 5.9E-52 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 SUPERFAMILY SSF160467 9 61 3.01E-6 T 28-03-2018 CP478_RS01425 0e6ef7a036dbc02f546eab47cc3f24e1 210 SUPERFAMILY SSF50891 89 209 4.55E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 Pfam PF01458 Uncharacterized protein family (UPF0051) 622 817 2.9E-70 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 Gene3D G3DSA:3.10.28.10 391 483 1.1E-7 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 Gene3D G3DSA:3.10.28.10 484 571 3.4E-5 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 609 837 5.7E-110 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 PRINTS PR00379 Intein signature 606 615 2.4E-7 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 PRINTS PR00379 Intein signature 588 605 2.4E-7 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 PRINTS PR00379 Intein signature 385 397 2.4E-7 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 PRINTS PR00379 Intein signature 485 497 2.4E-7 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 PRINTS PR00379 Intein signature 310 323 2.4E-7 T 28-03-2018 IPR006142 Intein GO:0016539 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 SMART SM00305 571 617 7.8E-9 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 SUPERFAMILY SSF101960 54 256 1.57E-47 T 28-03-2018 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 590 612 2.4E-7 T 28-03-2018 IPR030934 Intein C-terminal splicing region CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 SMART SM00306 251 371 1.6E-20 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 SUPERFAMILY SSF51294 252 421 3.14E-32 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 SUPERFAMILY SSF101960 609 843 1.27E-85 T 28-03-2018 CP478_RS08010 be3365f8d4a518b9e35c6e5e705caca4 846 Gene3D G3DSA:2.170.16.10 245 390 1.6E-13 T 28-03-2018 CP478_RS12600 95c762621ff04a38c96abff0cc1ff833 114 Gene3D G3DSA:1.10.10.60 4 32 0.0034 T 28-03-2018 CP478_RS12600 95c762621ff04a38c96abff0cc1ff833 114 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 19 66 1.8E-15 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CP478_RS12600 95c762621ff04a38c96abff0cc1ff833 114 SUPERFAMILY SSF46955 18 76 1.45E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS12600 95c762621ff04a38c96abff0cc1ff833 114 Gene3D G3DSA:1.10.10.10 33 78 2.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12600 95c762621ff04a38c96abff0cc1ff833 114 Pfam PF12728 Helix-turn-helix domain 20 69 4.0E-13 T 28-03-2018 CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 SUPERFAMILY SSF55718 510 626 3.3E-21 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 Pfam PF00753 Metallo-beta-lactamase superfamily 97 324 1.1E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 Pfam PF14863 Alkyl sulfatase dimerisation 361 499 6.1E-58 T 28-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 Pfam PF14864 Alkyl sulfatase C-terminal 510 626 1.8E-32 T 28-03-2018 IPR029229 Alkyl sulfatase, C-terminal CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 SUPERFAMILY SSF56281 19 501 1.54E-146 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 SMART SM00849 101 324 2.5E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 Gene3D G3DSA:3.30.1050.10 503 626 9.0E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS20545 e601b7aaac8c3ffb96e94fdd423f107c 626 Gene3D G3DSA:3.60.15.10 74 378 1.9E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS11820 1bd2650d6aad090a7d0a9a657a3bcf28 516 TIGRFAM TIGR03459 crt_membr: carotene biosynthesis associated membrane protein 37 496 2.1E-208 T 28-03-2018 IPR017822 Carotene biosynthesis-associated membrane protein, type-1 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 1.3E-37 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 Pfam PF00281 Ribosomal protein L5 31 87 2.8E-26 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 PIRSF PIRSF002161 4 187 1.1E-62 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 43.143 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 SUPERFAMILY SSF55282 10 185 5.18E-72 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03880 6184165a5f017e834a44d7e08387937c 187 Gene3D G3DSA:3.30.1440.10 8 186 6.0E-72 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 SUPERFAMILY SSF51717 6 272 1.57E-90 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 Pfam PF00809 Pterin binding enzyme 9 255 1.4E-85 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 8 23 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 42 55 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 7 269 4.3E-95 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CP478_RS19700 053b7df10761749a4ee0e12ec78fc3ba 280 Gene3D G3DSA:3.20.20.20 1 280 2.6E-100 T 28-03-2018 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 SUPERFAMILY SSF50692 1 120 2.36E-48 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS19665 425fad28c345b740abc8feea093bef73 139 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 73.251 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 PIRSF PIRSF006246 1 132 2.9E-52 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 1.3E-49 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 Gene3D G3DSA:2.40.40.20 1 117 9.1E-53 T 28-03-2018 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 Pfam PF02261 Aspartate decarboxylase 1 113 1.3E-50 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CP478_RS19665 425fad28c345b740abc8feea093bef73 139 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 3.0E-38 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 336 61.801 T 28-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 SUPERFAMILY SSF53659 2 336 7.87E-109 T 28-03-2018 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 SMART SM01329 2 332 2.0E-159 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 231 250 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 Gene3D G3DSA:3.40.718.10 1 336 4.9E-111 T 28-03-2018 CP478_RS16380 1f30b823d119a6318124a904e9baa11a 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 330 6.3E-86 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CP478_RS15480 7efdeb985d70e4908d67756ea913bbd0 71 SUPERFAMILY SSF143120 2 44 3.66E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS15480 7efdeb985d70e4908d67756ea913bbd0 71 Gene3D G3DSA:3.40.1620.10 1 36 7.5E-13 T 28-03-2018 CP478_RS15480 7efdeb985d70e4908d67756ea913bbd0 71 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 36 4.3E-9 T 28-03-2018 CP478_RS15480 7efdeb985d70e4908d67756ea913bbd0 71 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 46 2.0E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 Gene3D G3DSA:3.40.50.1820 1 273 1.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 Pfam PF00561 alpha/beta hydrolase fold 23 257 3.1E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 SUPERFAMILY SSF53474 1 269 1.57E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 7.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 219 233 7.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00425 89cbadeab93107c396c39d1e5347090f 276 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 7.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 Gene3D G3DSA:2.40.280.10 12 130 1.0E-49 T 28-03-2018 IPR023620 Small protein B CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 135 3.0E-68 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 158 69.341 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 SUPERFAMILY SSF74982 8 135 7.19E-50 T 28-03-2018 IPR023620 Small protein B CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 152 1.8E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CP478_RS16970 46c93ae708a94f75c6a4ef2ba2df6d18 160 Pfam PF01668 SmpB protein 12 152 1.9E-58 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 SUPERFAMILY SSF51230 122 210 4.32E-25 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 SUPERFAMILY SSF51230 1 92 1.96E-27 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 553 8.0E-272 T 28-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Gene3D G3DSA:3.30.559.10 293 546 1.0E-75 T 28-03-2018 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Gene3D G3DSA:4.10.320.10 247 289 9.7E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 SUPERFAMILY SSF47005 239 281 5.49E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 SUPERFAMILY SSF52777 304 544 7.12E-75 T 28-03-2018 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Gene3D G3DSA:3.90.1170.30 46 164 3.7E-37 T 28-03-2018 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Gene3D G3DSA:3.90.1170.30 2 45 1.0E-18 T 28-03-2018 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Gene3D G3DSA:3.90.1170.30 165 246 2.0E-9 T 28-03-2018 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Pfam PF00364 Biotin-requiring enzyme 5 76 1.0E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Pfam PF00364 Biotin-requiring enzyme 124 195 2.5E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 146 175 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Pfam PF02817 e3 binding domain 243 277 1.1E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS12035 7affc963ccda23e6d5cfde1e8b75f515 553 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 317 544 4.9E-71 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CP478_RS12625 138297bbb9b780e42e79ce7cb2f9d0cb 505 Pfam PF01523 Putative modulator of DNA gyrase 34 345 4.4E-50 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CP478_RS12625 138297bbb9b780e42e79ce7cb2f9d0cb 505 Gene3D G3DSA:3.30.2290.10 2 236 6.4E-46 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CP478_RS12625 138297bbb9b780e42e79ce7cb2f9d0cb 505 SUPERFAMILY SSF111283 16 496 7.98E-93 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CP478_RS16930 276e298701f739258514cacec0301b57 376 Gene3D G3DSA:2.40.110.10 110 191 2.6E-17 T 28-03-2018 CP478_RS16930 276e298701f739258514cacec0301b57 376 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 223 355 5.7E-35 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CP478_RS16930 276e298701f739258514cacec0301b57 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 85 1.9E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16930 276e298701f739258514cacec0301b57 376 SUPERFAMILY SSF47203 214 370 5.64E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS16930 276e298701f739258514cacec0301b57 376 Gene3D G3DSA:1.20.140.10 192 375 1.9E-18 T 28-03-2018 CP478_RS16930 276e298701f739258514cacec0301b57 376 PIRSF PIRSF016578 1 376 1.4E-121 T 28-03-2018 CP478_RS16930 276e298701f739258514cacec0301b57 376 SUPERFAMILY SSF56645 10 200 5.37E-30 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS16930 276e298701f739258514cacec0301b57 376 Gene3D G3DSA:1.10.540.10 3 106 7.1E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS07685 8e0dd72cdf58c8250b8678978248e9fd 274 SUPERFAMILY SSF53335 25 273 4.68E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS07685 8e0dd72cdf58c8250b8678978248e9fd 274 Pfam PF13649 Methyltransferase domain 53 145 8.8E-18 T 28-03-2018 CP478_RS07685 8e0dd72cdf58c8250b8678978248e9fd 274 Gene3D G3DSA:3.40.50.150 26 274 1.2E-28 T 28-03-2018 CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 262 6.7E-98 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 192 5.0E-41 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 SUPERFAMILY SSF100939 1 261 4.32E-57 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 PIRSF PIRSF006493 1 271 2.2E-100 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 SMART SM00559 52 184 4.6E-51 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 Gene3D G3DSA:2.40.290.10 1 186 5.4E-39 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CP478_RS05110 3bebc5415c5a260be4b02437b3d53251 273 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 260 32.123 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 SUPERFAMILY SSF140459 8 83 3.92E-22 T 28-03-2018 CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 Gene3D G3DSA:3.40.50.1820 116 322 3.0E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 Pfam PF00934 PE family 1 92 9.6E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 Pfam PF08237 PE-PPE domain 154 375 2.1E-71 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 Gene3D G3DSA:1.10.287.1060 1 101 1.9E-5 T 28-03-2018 CP478_RS00875 030c1160dc802c1674e33cce96e53435 468 SUPERFAMILY SSF53474 118 297 1.16E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS05960 da743157797d0074234935d7915dbfd8 764 SUPERFAMILY SSF140459 8 83 8.63E-26 T 28-03-2018 CP478_RS05960 da743157797d0074234935d7915dbfd8 764 PRINTS PR01228 Eggshell protein signature 379 389 2.7E-6 T 28-03-2018 CP478_RS05960 da743157797d0074234935d7915dbfd8 764 PRINTS PR01228 Eggshell protein signature 269 280 2.7E-6 T 28-03-2018 CP478_RS05960 da743157797d0074234935d7915dbfd8 764 PRINTS PR01228 Eggshell protein signature 405 423 2.7E-6 T 28-03-2018 CP478_RS05960 da743157797d0074234935d7915dbfd8 764 PRINTS PR01228 Eggshell protein signature 354 369 2.7E-6 T 28-03-2018 CP478_RS05960 da743157797d0074234935d7915dbfd8 764 Pfam PF00934 PE family 1 92 4.3E-36 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09885 aec9967902a76c0ee2e6fdc6e730f970 234 Gene3D G3DSA:1.10.10.60 8 63 1.9E-11 T 28-03-2018 CP478_RS09885 aec9967902a76c0ee2e6fdc6e730f970 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09885 aec9967902a76c0ee2e6fdc6e730f970 234 SUPERFAMILY SSF48498 93 228 1.89E-29 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS09885 aec9967902a76c0ee2e6fdc6e730f970 234 SUPERFAMILY SSF46689 10 84 1.12E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS09885 aec9967902a76c0ee2e6fdc6e730f970 234 Gene3D G3DSA:1.10.357.10 64 233 1.0E-33 T 28-03-2018 CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 16 112 2.0E-18 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 155 210 1.1E-25 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 14 214 22.864 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 15 118 3.3E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 SUPERFAMILY SSF69754 16 126 2.22E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CP478_RS17775 81fb4c47d0d59bd483d30340869826e2 214 Gene3D G3DSA:3.30.160.100 13 118 2.6E-23 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 SUPERFAMILY SSF54637 165 277 2.75E-24 T 28-03-2018 IPR029069 HotDog domain CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 Pfam PF01575 MaoC like domain 162 256 3.6E-26 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 Gene3D G3DSA:3.10.129.10 33 163 2.5E-23 T 28-03-2018 CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 PRINTS PR01483 Fatty acid synthase signature 178 200 1.3E-9 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 PRINTS PR01483 Fatty acid synthase signature 200 221 1.3E-9 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 Gene3D G3DSA:3.10.129.10 164 276 8.8E-22 T 28-03-2018 CP478_RS01305 bf291feaa5ae60090c14356b916221bf 280 SUPERFAMILY SSF54637 40 161 4.48E-9 T 28-03-2018 IPR029069 HotDog domain CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 SUPERFAMILY SSF52954 327 421 9.65E-22 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 Pfam PF13393 Histidyl-tRNA synthetase 12 311 1.0E-42 T 28-03-2018 CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 Pfam PF03129 Anticodon binding domain 331 419 1.8E-14 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 PIRSF PIRSF001549 3 421 2.2E-112 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 SUPERFAMILY SSF55681 8 316 9.19E-85 T 28-03-2018 CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 Gene3D G3DSA:3.40.50.800 326 422 2.6E-18 T 28-03-2018 IPR004154 Anticodon-binding CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 9 409 3.2E-134 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 Gene3D G3DSA:3.30.930.10 3 325 4.7E-66 T 28-03-2018 CP478_RS14140 2875dc360c5d51996beae96a4223f23a 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 5 420 31.218 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 SUPERFAMILY SSF53790 6 66 1.31E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 SUPERFAMILY SSF53790 99 298 1.31E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Gene3D G3DSA:3.30.950.10 167 309 5.1E-30 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 245 2.0E-40 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Pfam PF02602 Uroporphyrinogen-III synthase HemD 309 539 2.5E-62 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Gene3D G3DSA:3.40.50.10090 327 455 7.3E-30 T 28-03-2018 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 SUPERFAMILY SSF69618 295 546 5.75E-69 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Gene3D G3DSA:3.40.1010.10 10 166 1.1E-28 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS02735 7386060740bbd245f0cec9ace8af7f31 565 Gene3D G3DSA:3.40.50.10090 456 550 2.1E-21 T 28-03-2018 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 SUPERFAMILY SSF55874 334 501 4.58E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05660 596cbdc4205522751f914141752e0d42 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 457 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 1.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 SMART SM00388 277 344 7.5E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 SMART SM00387 387 502 2.2E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05660 596cbdc4205522751f914141752e0d42 509 Gene3D G3DSA:3.30.565.10 347 508 1.3E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05660 596cbdc4205522751f914141752e0d42 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 344 6.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 SMART SM00304 207 269 7.4E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 SUPERFAMILY SSF47384 268 344 4.71E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 499 3.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05660 596cbdc4205522751f914141752e0d42 509 Gene3D G3DSA:1.10.287.130 268 340 1.0E-15 T 28-03-2018 CP478_RS05660 596cbdc4205522751f914141752e0d42 509 Pfam PF00672 HAMP domain 208 264 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 Pfam PF00732 GMC oxidoreductase 9 299 9.3E-55 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 PIRSF PIRSF000137 411 479 8.2E-19 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 PIRSF PIRSF000137 3 317 7.2E-55 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 PIRSF PIRSF000137 326 407 7.6E-8 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 Pfam PF05199 GMC oxidoreductase 358 474 5.9E-29 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 SUPERFAMILY SSF51905 418 478 4.07E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 SUPERFAMILY SSF51905 7 287 4.07E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 Gene3D G3DSA:3.50.50.60 1 479 6.5E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 SUPERFAMILY SSF54373 295 433 2.22E-11 T 28-03-2018 CP478_RS03770 7247ef99d35181711c67651431b341c8 479 TIGRFAM TIGR03970 Rv0697: dehydrogenase, Rv0697 family 8 479 7.7E-230 T 28-03-2018 IPR023978 Glucose-methanol-choline oxidoreductase, actinobacteria CP478_RS18480 26fd70824d6b10723294e88bb8408e8a 82 SUPERFAMILY SSF52096 1 82 7.15E-11 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS18480 26fd70824d6b10723294e88bb8408e8a 82 Gene3D G3DSA:3.90.226.10 1 82 2.8E-10 T 28-03-2018 CP478_RS06500 bc97d244e790ad9d169aabdb1539a52b 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 475 533 7.2E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS06500 bc97d244e790ad9d169aabdb1539a52b 538 Gene3D G3DSA:1.10.10.60 434 512 1.7E-6 T 28-03-2018 CP478_RS12085 8cb20a3f0c2ee2843a0590fcc3ebf6ce 520 SUPERFAMILY SSF53474 77 165 1.73E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12085 8cb20a3f0c2ee2843a0590fcc3ebf6ce 520 SUPERFAMILY SSF53474 382 494 1.73E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12085 8cb20a3f0c2ee2843a0590fcc3ebf6ce 520 SUPERFAMILY SSF53474 206 273 1.73E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12085 8cb20a3f0c2ee2843a0590fcc3ebf6ce 520 Pfam PF00561 alpha/beta hydrolase fold 102 497 5.6E-90 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS12085 8cb20a3f0c2ee2843a0590fcc3ebf6ce 520 Gene3D G3DSA:3.40.50.1820 42 508 2.4E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16445 150e5fa87e34b27741f7586649adf663 373 Gene3D G3DSA:2.120.10.30 69 280 2.2E-14 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS16445 150e5fa87e34b27741f7586649adf663 373 SUPERFAMILY SSF50952 80 336 5.75E-13 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CP478_RS16445 150e5fa87e34b27741f7586649adf663 373 Pfam PF07995 Glucose / Sorbosone dehydrogenase 86 249 4.4E-15 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CP478_RS09370 98faf7b6b9b401f4ebb2712fc07dced8 272 Pfam PF05853 beta-keto acid cleavage enzyme 3 268 1.7E-86 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CP478_RS09370 98faf7b6b9b401f4ebb2712fc07dced8 272 Gene3D G3DSA:3.20.20.70 1 272 4.4E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS01380 644aa63f965eb490e7e7a96e266bf345 556 Pfam PF00823 PPE family 8 164 9.0E-57 T 28-03-2018 IPR000030 PPE family CP478_RS01380 644aa63f965eb490e7e7a96e266bf345 556 SUPERFAMILY SSF140459 5 177 2.22E-59 T 28-03-2018 CP478_RS01380 644aa63f965eb490e7e7a96e266bf345 556 Gene3D G3DSA:1.10.287.1060 24 112 2.4E-4 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 PRINTS PR01228 Eggshell protein signature 209 220 2.8E-6 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 PRINTS PR01228 Eggshell protein signature 318 328 2.8E-6 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 PRINTS PR01228 Eggshell protein signature 342 360 2.8E-6 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 PRINTS PR01228 Eggshell protein signature 292 307 2.8E-6 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 Pfam PF00934 PE family 1 93 2.6E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 SUPERFAMILY SSF140459 8 83 3.92E-24 T 28-03-2018 CP478_RS07895 7f6c2d0739030bd8125cc04506d9efe2 491 Gene3D G3DSA:1.10.287.1060 1 101 0.0016 T 28-03-2018 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 Gene3D G3DSA:3.60.120.10 1 450 3.8E-85 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 PRINTS PR00095 Anthranilate synthase component I signature 380 394 1.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 PRINTS PR00095 Anthranilate synthase component I signature 286 299 1.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 PRINTS PR00095 Anthranilate synthase component I signature 395 409 1.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 Pfam PF00425 chorismate binding enzyme 186 438 3.1E-61 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 28 448 2.2E-197 T 28-03-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS13005 a11316f389f71a8f75889ce5b19b8fb0 450 SUPERFAMILY SSF56322 34 446 5.76E-92 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 SUPERFAMILY SSF52540 11 201 1.89E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 Pfam PF00005 ABC transporter 21 151 7.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 Pfam PF00005 ABC transporter 305 441 4.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 Gene3D G3DSA:1.20.5.170 483 591 1.7E-4 T 28-03-2018 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 Gene3D G3DSA:3.40.50.300 2 236 3.8E-42 T 28-03-2018 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 SUPERFAMILY SSF52540 276 489 1.22E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 318 338 4.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 372 387 4.5E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 SMART SM00382 29 207 3.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 SMART SM00382 314 493 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09115 f534e58daba58e19fa6b6a118c8f4c01 591 Gene3D G3DSA:3.40.50.300 271 482 1.2E-38 T 28-03-2018 CP478_RS10405 e2e89210636132333e7749afb9883384 334 Pfam PF00107 Zinc-binding dehydrogenase 152 286 3.1E-18 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS10405 e2e89210636132333e7749afb9883384 334 SUPERFAMILY SSF50129 1 141 1.17E-36 T 28-03-2018 IPR011032 GroES-like CP478_RS10405 e2e89210636132333e7749afb9883384 334 SUPERFAMILY SSF51735 113 241 4.45E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10405 e2e89210636132333e7749afb9883384 334 SMART SM00829 10 332 3.0E-48 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS10405 e2e89210636132333e7749afb9883384 334 Gene3D G3DSA:3.90.180.10 1 138 3.1E-40 T 28-03-2018 CP478_RS10405 e2e89210636132333e7749afb9883384 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 91 3.4E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS10405 e2e89210636132333e7749afb9883384 334 Gene3D G3DSA:3.40.50.720 139 271 2.7E-25 T 28-03-2018 CP478_RS10405 e2e89210636132333e7749afb9883384 334 Gene3D G3DSA:3.90.180.10 272 333 0.032 T 28-03-2018 CP478_RS10405 e2e89210636132333e7749afb9883384 334 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.40.47.10 2824 2993 4.9E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 840 864 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1239 1260 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 435 453 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 730 748 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1345 1368 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1462 1483 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 560 579 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1217 1239 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1426 1445 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 1324 1343 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 409 429 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 PRINTS PR01483 Fatty acid synthase signature 540 558 2.2E-112 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.40.366.10 34 374 6.1E-29 T 28-03-2018 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2816 2941 6.9E-29 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF53901 2586 2815 1.25E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2575 2806 3.5E-38 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF52151 284 367 1.39E-17 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF52151 34 189 1.39E-17 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Pfam PF08354 Domain of unknown function (DUF1729) 846 898 5.3E-20 T 28-03-2018 IPR013565 Domain of unknown function DUF1729 GO:0004318|GO:0055114 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Pfam PF01575 MaoC like domain 1199 1317 7.2E-31 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF54637 1216 1325 1.13E-22 T 28-03-2018 IPR029069 HotDog domain CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF53901 2777 2991 3.94E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.20.20.70 392 915 6.4E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.10.129.10 1052 1196 4.8E-9 T 28-03-2018 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1335 1720 4.5E-5 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Pfam PF00698 Acyl transferase domain 1333 1536 3.2E-35 T 28-03-2018 IPR014043 Acyl transferase CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF52151 1563 1584 1.19E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF52151 1624 1704 1.19E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF52151 1331 1475 1.19E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF51412 396 669 1.56E-16 T 28-03-2018 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.10.129.10 1198 1330 4.0E-23 T 28-03-2018 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SUPERFAMILY SSF51735 2112 2363 5.2E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.40.366.10 1331 1725 2.6E-52 T 28-03-2018 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 SMART SM00825 Beta-ketoacyl synthase 2574 2943 0.0067 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.40.47.10 2434 2820 1.9E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS13825 60fc947a006c5c3c68bd9424ba573cac 3069 Gene3D G3DSA:3.40.50.720 2102 2359 3.2E-10 T 28-03-2018 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 Pfam PF01765 Ribosome recycling factor 21 183 3.0E-60 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.297 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-65 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 SUPERFAMILY SSF55194 3 184 2.09E-66 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 Gene3D G3DSA:1.10.132.20 75 184 1.4E-35 T 28-03-2018 CP478_RS15750 2f0582005d88e2ba983c8ad02cd809bf 185 Gene3D G3DSA:1.10.132.20 2 74 4.5E-9 T 28-03-2018 CP478_RS02295 b3e6b156a7bf82f678da1edd663a4cc6 164 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 78 163 3.8E-14 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Pfam PF06470 SMC proteins Flexible Hinge Domain 514 628 8.7E-20 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 PIRSF PIRSF005719 1 1200 8.0E-277 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1192 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1185 4.6E-74 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 SUPERFAMILY SSF52540 2 207 9.91E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 SUPERFAMILY SSF52540 994 1187 9.91E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Gene3D G3DSA:3.40.50.300 2 209 1.4E-39 T 28-03-2018 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Gene3D G3DSA:1.20.5.50 376 500 5.3E-7 T 28-03-2018 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1194 21.879 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 SMART SM00968 513 629 1.2E-19 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 Gene3D G3DSA:3.40.50.300 653 1197 2.9E-26 T 28-03-2018 CP478_RS15960 b8c463bc99f60ac194cb91428eab0936 1205 SUPERFAMILY SSF75553 467 674 3.4E-29 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 Gene3D G3DSA:1.10.357.10 71 224 2.3E-12 T 28-03-2018 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 9.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 SUPERFAMILY SSF48498 88 168 1.28E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 SUPERFAMILY SSF46689 3 85 1.33E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 Gene3D G3DSA:1.10.260.40 39 70 8.2E-10 T 28-03-2018 CP478_RS01255 00b8a69218025d70bcc9dbb29bd914b5 229 Gene3D G3DSA:1.10.10.60 1 38 4.3E-11 T 28-03-2018 CP478_RS05685 9ad98c57ae9ede9b887ee64b0a4cdfbf 391 Pfam PF00823 PPE family 5 161 3.1E-59 T 28-03-2018 IPR000030 PPE family CP478_RS05685 9ad98c57ae9ede9b887ee64b0a4cdfbf 391 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 310 387 2.1E-21 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS05685 9ad98c57ae9ede9b887ee64b0a4cdfbf 391 SUPERFAMILY SSF140459 2 174 2.46E-60 T 28-03-2018 CP478_RS05685 9ad98c57ae9ede9b887ee64b0a4cdfbf 391 Gene3D G3DSA:1.10.287.1060 20 104 9.7E-6 T 28-03-2018 CP478_RS21410 0bca6f65345c733ed9855ce6619f93f4 347 Pfam PF13614 AAA domain 85 263 7.7E-58 T 28-03-2018 IPR025669 AAA domain CP478_RS21410 0bca6f65345c733ed9855ce6619f93f4 347 SUPERFAMILY SSF52540 85 339 9.08E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21410 0bca6f65345c733ed9855ce6619f93f4 347 Gene3D G3DSA:3.40.50.300 84 340 2.7E-59 T 28-03-2018 CP478_RS10580 c6ac4e5b8ac353152e15bb7a18ec221c 454 Pfam PF02720 Domain of unknown function (DUF222) 37 361 1.4E-99 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS10580 c6ac4e5b8ac353152e15bb7a18ec221c 454 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 1 97 7.0E-48 T 28-03-2018 CP478_RS10580 c6ac4e5b8ac353152e15bb7a18ec221c 454 SMART SM00507 352 404 2.7E-7 T 28-03-2018 IPR003615 HNH nuclease CP478_RS10580 c6ac4e5b8ac353152e15bb7a18ec221c 454 Gene3D G3DSA:1.10.10.10 64 147 3.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10580 c6ac4e5b8ac353152e15bb7a18ec221c 454 Gene3D G3DSA:3.40.1800.10 343 421 4.0E-4 T 28-03-2018 CP478_RS06980 9700aae31c897d2c4b55116b511aa364 158 Gene3D G3DSA:3.40.50.1240 1 158 6.4E-27 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS06980 9700aae31c897d2c4b55116b511aa364 158 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 71 1.8E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS06980 9700aae31c897d2c4b55116b511aa364 158 SUPERFAMILY SSF53254 1 141 1.73E-19 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS06980 9700aae31c897d2c4b55116b511aa364 158 SMART SM00855 1 105 7.1E-4 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-36 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-36 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-36 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 Pfam PF00453 Ribosomal protein L20 3 109 1.1E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 Gene3D G3DSA:1.10.1900.20 56 116 3.2E-24 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 2.8E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 SUPERFAMILY SSF74731 3 117 7.46E-43 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 9.0E-22 T 28-03-2018 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.454 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS08995 e2929259cd2d70e604c73c9419f3bc0f 129 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS16165 ed7580a190207257591a9197e0782803 428 Gene3D G3DSA:3.40.50.2000 267 410 1.4E-32 T 28-03-2018 CP478_RS16165 ed7580a190207257591a9197e0782803 428 SUPERFAMILY SSF53756 32 410 2.9E-69 T 28-03-2018 CP478_RS16165 ed7580a190207257591a9197e0782803 428 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 281 406 1.9E-10 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CP478_RS16165 ed7580a190207257591a9197e0782803 428 Gene3D G3DSA:3.40.50.2000 32 266 5.9E-19 T 28-03-2018 CP478_RS05825 9afcbaa200ad0ed56b5256fa8dbab458 287 Pfam PF13230 Glutamine amidotransferases class-II 1 251 2.2E-22 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 CP478_RS05825 9afcbaa200ad0ed56b5256fa8dbab458 287 Gene3D G3DSA:3.60.20.10 1 261 4.7E-39 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS05825 9afcbaa200ad0ed56b5256fa8dbab458 287 SUPERFAMILY SSF56235 2 252 3.18E-33 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 SUPERFAMILY SSF51556 60 120 1.48E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 SUPERFAMILY SSF51556 186 465 1.48E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 Gene3D G3DSA:3.20.20.140 169 466 1.4E-40 T 28-03-2018 CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 Pfam PF07969 Amidohydrolase family 49 533 1.4E-106 T 28-03-2018 IPR013108 Amidohydrolase 3 CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 SUPERFAMILY SSF51338 8 78 1.23E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 Gene3D G3DSA:2.30.40.10 5 73 2.4E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS11190 9b2385ce59b742a4c44a9a126c0608e4 534 Gene3D G3DSA:3.20.20.140 74 140 0.28 T 28-03-2018 CP478_RS13970 d7223c210deae2ab1dc0c2da22fbd4f2 124 Gene3D G3DSA:1.20.5.190 4 36 0.0017 T 28-03-2018 CP478_RS13970 d7223c210deae2ab1dc0c2da22fbd4f2 124 Gene3D G3DSA:3.90.20.10 52 123 1.6E-6 T 28-03-2018 CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 PIRSF PIRSF000706 2 161 3.5E-38 T 28-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 PIRSF PIRSF000706 156 246 2.5E-33 T 28-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 SUPERFAMILY SSF56112 19 242 8.75E-34 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 Gene3D G3DSA:3.30.200.20 2 93 1.3E-19 T 28-03-2018 CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 Gene3D G3DSA:1.10.510.10 134 233 1.3E-11 T 28-03-2018 CP478_RS20850 c3c3ff7efdbc8af27cc521eb4b992fca 251 Pfam PF01636 Phosphotransferase enzyme family 151 239 4.8E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Pfam PF13840 ACT domain 341 403 1.2E-12 T 28-03-2018 IPR027795 GATS-like ACT domain CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 PIRSF PIRSF000726 54 414 1.1E-126 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 PIRSF PIRSF000726 1 60 5.1E-21 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Gene3D G3DSA:3.30.70.260 236 336 2.2E-22 T 28-03-2018 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Gene3D G3DSA:3.30.70.260 337 421 2.3E-19 T 28-03-2018 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 SUPERFAMILY SSF53633 4 243 2.49E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Pfam PF00696 Amino acid kinase family 3 231 3.1E-54 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Gene3D G3DSA:3.40.1160.10 1 235 7.9E-73 T 28-03-2018 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 2.3E-121 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 SUPERFAMILY SSF55021 332 409 1.03E-20 T 28-03-2018 CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 Pfam PF01842 ACT domain 268 330 5.1E-11 T 28-03-2018 IPR002912 ACT domain CP478_RS20265 84e21ae56adc8c55dad882c0dbca1129 421 SUPERFAMILY SSF55021 250 330 2.65E-18 T 28-03-2018 CP478_RS09670 3e96194717b1d7740ac2e7c0e96d6a92 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 35 68 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CP478_RS09670 3e96194717b1d7740ac2e7c0e96d6a92 446 SUPERFAMILY SSF56176 11 201 1.26E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS09670 3e96194717b1d7740ac2e7c0e96d6a92 446 Gene3D G3DSA:3.30.465.10 90 229 9.8E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS09670 3e96194717b1d7740ac2e7c0e96d6a92 446 Pfam PF01565 FAD binding domain 35 169 4.9E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS09670 3e96194717b1d7740ac2e7c0e96d6a92 446 Gene3D G3DSA:3.30.43.10 1 87 1.0E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS17220 37b7b43a4f94f02ef0294aefd6abde6b 409 Pfam PF00823 PPE family 5 161 5.8E-55 T 28-03-2018 IPR000030 PPE family CP478_RS17220 37b7b43a4f94f02ef0294aefd6abde6b 409 SUPERFAMILY SSF140459 3 169 4.97E-54 T 28-03-2018 CP478_RS17220 37b7b43a4f94f02ef0294aefd6abde6b 409 Gene3D G3DSA:1.10.287.1060 19 105 1.1E-5 T 28-03-2018 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SMART SM00240 229 279 8.9E-16 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SMART SM00240 28 78 8.3E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SMART SM00382 344 528 3.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Pfam PF00498 FHA domain 29 92 6.9E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Pfam PF00498 FHA domain 230 293 4.3E-15 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Gene3D G3DSA:2.60.200.20 1 105 3.6E-15 T 28-03-2018 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SUPERFAMILY SSF49879 5 115 1.03E-18 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SUPERFAMILY SSF49879 170 300 1.91E-26 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Gene3D G3DSA:2.60.200.20 144 302 6.8E-20 T 28-03-2018 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 SUPERFAMILY SSF52540 319 540 9.09E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Pfam PF01061 ABC-2 type transporter 596 810 9.9E-20 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Pfam PF00005 ABC transporter 335 482 5.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS09530 275a93292aba610fc84d28736a8d0ecb 865 Gene3D G3DSA:3.40.50.300 318 593 2.8E-63 T 28-03-2018 CP478_RS04935 9f2a973dd8c8c30d7da40c42d7d04c59 243 Gene3D G3DSA:1.10.12.10 189 243 5.9E-11 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS04935 9f2a973dd8c8c30d7da40c42d7d04c59 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 90 110 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS04935 9f2a973dd8c8c30d7da40c42d7d04c59 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 242 7.5E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS04935 9f2a973dd8c8c30d7da40c42d7d04c59 243 Gene3D G3DSA:3.90.226.10 2 188 3.0E-49 T 28-03-2018 CP478_RS04935 9f2a973dd8c8c30d7da40c42d7d04c59 243 SUPERFAMILY SSF52096 5 242 1.89E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 Pfam PF00005 ABC transporter 16 166 6.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 SMART SM00382 23 216 6.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 Pfam PF03459 TOBE domain 295 359 3.3E-14 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 Gene3D G3DSA:2.40.50.100 277 355 7.2E-15 T 28-03-2018 CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 Gene3D G3DSA:3.40.50.300 15 244 1.5E-58 T 28-03-2018 CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 SUPERFAMILY SSF50331 241 359 3.01E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CP478_RS10105 b1e5fec20efeca2212fab277a7670d3c 369 SUPERFAMILY SSF52540 11 240 1.42E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19675 60982287d2e9826a7520fd8850763303 303 SUPERFAMILY SSF51735 13 177 1.55E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19675 60982287d2e9826a7520fd8850763303 303 Pfam PF10727 Rossmann-like domain 8 128 3.1E-57 T 28-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CP478_RS19675 60982287d2e9826a7520fd8850763303 303 Pfam PF10728 Domain of unknown function (DUF2520) 145 286 9.4E-38 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CP478_RS19675 60982287d2e9826a7520fd8850763303 303 SUPERFAMILY SSF48179 179 292 8.84E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS19675 60982287d2e9826a7520fd8850763303 303 Gene3D G3DSA:3.40.50.720 10 177 3.6E-16 T 28-03-2018 CP478_RS19675 60982287d2e9826a7520fd8850763303 303 Gene3D G3DSA:1.10.1040.20 178 290 2.7E-29 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 137 149 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 Gene3D G3DSA:3.30.420.40 257 508 6.0E-78 T 28-03-2018 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 SUPERFAMILY SSF53067 262 505 2.48E-82 T 28-03-2018 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 Gene3D G3DSA:3.30.420.40 2 256 5.5E-84 T 28-03-2018 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 Hamap MF_00186 Glycerol kinase [glpK]. 5 505 55.007 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 PIRSF PIRSF000538 5 508 1.8E-158 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 370 390 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 268 458 6.4E-64 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 259 1.1E-69 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 504 1.5E-226 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CP478_RS20190 40f781d85e6bef88cdd25ab24017a48f 508 SUPERFAMILY SSF53067 7 262 5.46E-85 T 28-03-2018 CP478_RS13585 b232206900f36caa876a01dc4f89de04 421 Pfam PF07859 alpha/beta hydrolase fold 173 379 2.2E-21 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS13585 b232206900f36caa876a01dc4f89de04 421 SUPERFAMILY SSF53474 129 384 1.34E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS13585 b232206900f36caa876a01dc4f89de04 421 Gene3D G3DSA:3.40.50.1820 108 402 1.4E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 SUPERFAMILY SSF55681 2 248 4.97E-86 T 28-03-2018 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 SUPERFAMILY SSF50447 461 572 1.62E-15 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 880 2.9E-245 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 673 717 1.7E-16 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 SUPERFAMILY SSF101353 249 443 2.35E-53 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 903 164.344 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 SMART SM00863 673 717 2.0E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Pfam PF01411 tRNA synthetases class II (A) 5 574 1.3E-206 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Gene3D G3DSA:3.30.930.10 1 245 8.1E-95 T 28-03-2018 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 SUPERFAMILY SSF55186 577 723 4.06E-41 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Gene3D G3DSA:3.30.980.10 573 721 3.2E-38 T 28-03-2018 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 5.0E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 5.0E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 5.0E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 5.0E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 5.0E-27 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CP478_RS14010 96d22cf1294cf33a5876ef0b99692f61 904 Pfam PF02272 DHHA1 domain 754 896 1.9E-18 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00385 P450 superfamily signature 331 340 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00385 P450 superfamily signature 265 276 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00385 P450 superfamily signature 230 247 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00385 P450 superfamily signature 340 351 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 184 206 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 124 140 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 282 309 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 265 276 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 310 325 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 78 89 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 141 156 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 340 351 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 PRINTS PR00359 B-class P450 signature 331 340 3.8E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 SUPERFAMILY SSF48264 22 393 1.31E-85 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 Gene3D G3DSA:1.10.630.10 1 398 4.4E-71 T 28-03-2018 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 Pfam PF00067 Cytochrome P450 163 360 4.6E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19230 15db23b30c63affb3f100aa83a9701ba 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 38.261 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 409 4.2E-123 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PIRSF PIRSF001529 1 417 2.2E-130 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 1.5E-24 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 218 393 1.7E-24 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 Gene3D G3DSA:1.10.287.40 1 102 6.9E-21 T 28-03-2018 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 SUPERFAMILY SSF46589 2 111 1.99E-21 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 3.8E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 3.8E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 3.8E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 3.8E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 3.8E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 SUPERFAMILY SSF55681 124 418 9.95E-86 T 28-03-2018 CP478_RS20940 999505e470c15ab684f75dbf293b5e80 419 Gene3D G3DSA:3.30.930.10 104 419 1.0E-78 T 28-03-2018 CP478_RS10655 04e5a0ae66675f0ccc4ac112b7d60d48 98 PIRSF PIRSF029218 2 98 7.1E-34 T 28-03-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 CP478_RS10655 04e5a0ae66675f0ccc4ac112b7d60d48 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 93 2.6E-23 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CP478_RS10655 04e5a0ae66675f0ccc4ac112b7d60d48 98 Gene3D G3DSA:3.30.2310.20 2 97 2.5E-5 T 28-03-2018 CP478_RS09445 3dd4cad2d4d4ef5368ebfd27f991a055 182 SUPERFAMILY SSF52833 5 182 1.12E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS09445 3dd4cad2d4d4ef5368ebfd27f991a055 182 Gene3D G3DSA:3.40.30.10 2 182 1.1E-41 T 28-03-2018 CP478_RS09445 3dd4cad2d4d4ef5368ebfd27f991a055 182 Pfam PF00578 AhpC/TSA family 11 134 4.4E-20 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 535 1.1E-14 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 SUPERFAMILY SSF52540 16 50 2.05E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 SUPERFAMILY SSF52540 368 535 2.05E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 Gene3D G3DSA:3.40.50.300 1 559 1.0E-33 T 28-03-2018 CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 SUPERFAMILY SSF52540 1 224 1.84E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 579 1.2E-231 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CP478_RS09255 1282f1d74a5b8e6c74b2890e182cabdf 587 PIRSF PIRSF003128 1 584 1.5E-180 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CP478_RS15065 6591eed44db04be595fa8d2883f46537 104 SUPERFAMILY SSF54909 1 94 8.05E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS15065 6591eed44db04be595fa8d2883f46537 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 70 6.9E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CP478_RS15065 6591eed44db04be595fa8d2883f46537 104 Gene3D G3DSA:3.30.70.100 1 93 4.3E-23 T 28-03-2018 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 Gene3D G3DSA:1.20.1640.10 494 729 2.0E-30 T 28-03-2018 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 Gene3D G3DSA:1.20.1640.10 116 340 2.8E-28 T 28-03-2018 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 Pfam PF03176 MMPL family 427 738 1.9E-27 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 Pfam PF03176 MMPL family 48 396 4.4E-39 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 SUPERFAMILY SSF82866 135 339 5.89E-29 T 28-03-2018 CP478_RS01120 48efe5ad50c7ed39205ac5ac950f263d 944 SUPERFAMILY SSF82866 512 732 1.7E-30 T 28-03-2018 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Gene3D G3DSA:3.40.120.10 6 161 2.0E-30 T 28-03-2018 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 12 128 6.4E-31 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 SUPERFAMILY SSF53738 265 369 9.81E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 454 1.4E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Gene3D G3DSA:3.40.120.10 162 269 1.2E-29 T 28-03-2018 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Gene3D G3DSA:3.40.120.10 270 370 7.7E-27 T 28-03-2018 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 SUPERFAMILY SSF53738 7 127 1.65E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Gene3D G3DSA:3.30.310.50 371 464 1.9E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 259 5.2E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 268 373 9.8E-26 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 SUPERFAMILY SSF55957 374 455 9.42E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 6.1E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 6.1E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 223 6.1E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 6.1E-22 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS17855 68d278e9cdb79d72863022196749dca9 465 SUPERFAMILY SSF53738 159 261 6.28E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 321 1.0E-149 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 SUPERFAMILY SSF51735 2 321 3.58E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 325 55.639 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 315 1.6E-132 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 Gene3D G3DSA:3.90.25.10 245 329 6.1E-23 T 28-03-2018 CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 Gene3D G3DSA:3.90.25.10 203 244 1.0E-21 T 28-03-2018 CP478_RS08290 a1866140491d9cd9b262eb8a9b6d319c 340 Gene3D G3DSA:3.40.50.720 1 202 3.2E-22 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 525 1.5E-146 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 SUPERFAMILY SSF54810 404 525 2.62E-46 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Pfam PF00958 GMP synthase C terminal domain 432 524 2.4E-39 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 SUPERFAMILY SSF52402 191 445 5.29E-52 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Gene3D G3DSA:3.40.50.880 12 220 4.4E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 17 201 3.3E-74 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Gene3D G3DSA:3.40.50.620 221 399 2.5E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Gene3D G3DSA:3.30.300.10 400 525 1.3E-51 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 SUPERFAMILY SSF52317 7 235 2.52E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Pfam PF00117 Glutamine amidotransferase class-I 19 197 3.1E-37 T 28-03-2018 IPR017926 Glutamine amidotransferase CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00097 Anthranilate synthase component II signature 88 99 5.8E-7 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00097 Anthranilate synthase component II signature 175 188 5.8E-7 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00097 Anthranilate synthase component II signature 61 70 5.8E-7 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 1.8E-8 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 88 99 1.8E-8 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 61 70 1.8E-8 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Pfam PF02540 NAD synthase 215 257 1.0E-5 T 28-03-2018 IPR022310 NAD/GMP synthase CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 88 104 5.1E-5 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 58 72 5.1E-5 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 17 31 5.1E-5 T 28-03-2018 CP478_RS18590 e913ec1d485bce6a7731ad91215d4f69 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 14 525 52.954 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 8 504 4.1E-108 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 357 375 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 29 54 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 211 227 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 132 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 240 259 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 429 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 333 351 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 95 113 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 388 403 5.7E-40 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 Pfam PF01019 Gamma-glutamyltranspeptidase 22 507 3.2E-168 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS04205 6c008114e5d068798c392100fcb2158c 512 SUPERFAMILY SSF56235 6 511 1.68E-179 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11310 8336b09fa55653ed3fc6f69a551f0dbd 487 SUPERFAMILY SSF56436 384 433 4.55E-5 T 28-03-2018 IPR016187 C-type lectin fold CP478_RS11310 8336b09fa55653ed3fc6f69a551f0dbd 487 Gene3D G3DSA:3.20.20.190 92 292 3.1E-16 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS11310 8336b09fa55653ed3fc6f69a551f0dbd 487 SUPERFAMILY SSF51695 103 320 5.02E-22 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 367 487 7.7E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 SUPERFAMILY SSF52788 364 488 5.76E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 SMART SM00226 365 490 3.9E-55 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 Gene3D G3DSA:3.40.50.2300 363 496 1.7E-36 T 28-03-2018 CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 Pfam PF01758 Sodium Bile acid symporter family 62 258 4.9E-66 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CP478_RS14475 146804b3659916ec41b0ba0de78e2001 498 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 345 3.9E-138 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CP478_RS06280 13581404eec0362c31105bdd65cd3106 470 SUPERFAMILY SSF82866 196 419 1.27E-27 T 28-03-2018 CP478_RS06280 13581404eec0362c31105bdd65cd3106 470 Gene3D G3DSA:1.20.1640.10 186 417 7.3E-28 T 28-03-2018 CP478_RS06280 13581404eec0362c31105bdd65cd3106 470 Pfam PF03176 MMPL family 203 422 2.9E-24 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 SUPERFAMILY SSF46785 16 85 2.48E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 TIGRFAM TIGR01529 argR_whole: arginine repressor 20 169 2.1E-51 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 109 167 5.0E-27 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 Pfam PF02863 Arginine repressor, C-terminal domain 102 166 2.3E-24 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 SUPERFAMILY SSF55252 101 168 3.4E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 Gene3D G3DSA:1.10.10.10 10 84 7.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 Gene3D G3DSA:3.30.1360.40 95 166 4.9E-31 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 PRINTS PR01467 Bacterial arginine repressor signature 139 154 7.2E-28 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 PRINTS PR01467 Bacterial arginine repressor signature 36 49 7.2E-28 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 PRINTS PR01467 Bacterial arginine repressor signature 52 67 7.2E-28 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 PRINTS PR01467 Bacterial arginine repressor signature 109 122 7.2E-28 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 Hamap MF_00173 Arginine repressor [argR]. 1 170 59.237 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CP478_RS09065 87e5e3b28ff9e539dcac3ff1d93fc3a5 170 Pfam PF01316 Arginine repressor, DNA binding domain 16 85 2.2E-26 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 33 1134 12.251 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:3.90.1110.10 172 335 3.3E-68 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 373 1.4E-26 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF04563 RNA polymerase beta subunit 99 417 2.4E-21 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 ProSitePatterns PS01166 RNA polymerases beta chain signature. 876 888 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF04565 RNA polymerase Rpb2, domain 3 432 500 4.0E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF10385 RNA polymerase beta subunit external 1 domain 510 576 1.0E-27 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF00562 RNA polymerase Rpb2, domain 6 637 1056 3.5E-156 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:2.40.270.10 834 954 3.2E-47 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:2.40.270.10 706 806 1.5E-9 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:2.40.270.10 955 1034 1.5E-17 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:2.40.50.100 634 705 8.3E-25 T 28-03-2018 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:3.90.1100.10 566 633 4.4E-14 T 28-03-2018 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:3.90.1100.10 336 565 1.7E-80 T 28-03-2018 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Pfam PF04560 RNA polymerase Rpb2, domain 7 1058 1132 6.3E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 Gene3D G3DSA:3.90.1800.10 1059 1103 1.3E-10 T 28-03-2018 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 244 850 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS03600 f0cbddb7f56bbe144cafdf02e1d4a910 1172 SUPERFAMILY SSF64484 32 1142 0.0 T 28-03-2018 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 SUPERFAMILY SSF51064 134 188 3.4E-12 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 SUPERFAMILY SSF58014 48 127 4.97E-18 T 28-03-2018 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 Hamap MF_01151 Protein GrpE [grpE]. 2 188 15.044 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 Pfam PF01025 GrpE 47 187 4.8E-30 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 Gene3D G3DSA:2.30.22.10 132 193 5.8E-16 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 ProSitePatterns PS01071 grpE protein signature. 142 186 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 PRINTS PR00773 GrpE protein signature 139 154 1.1E-22 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 PRINTS PR00773 GrpE protein signature 91 106 1.1E-22 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 PRINTS PR00773 GrpE protein signature 167 186 1.1E-22 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 PRINTS PR00773 GrpE protein signature 63 79 1.1E-22 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CP478_RS01875 6cc6ff71153cdc3441b75268c63bd315 235 Gene3D G3DSA:3.90.20.20 42 131 1.1E-17 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CP478_RS18400 8aa030b74ddb95d52b63b7a55a1e371e 396 SUPERFAMILY SSF51395 301 387 7.57E-85 T 28-03-2018 CP478_RS18400 8aa030b74ddb95d52b63b7a55a1e371e 396 SUPERFAMILY SSF51395 8 266 7.57E-85 T 28-03-2018 CP478_RS18400 8aa030b74ddb95d52b63b7a55a1e371e 396 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 11 248 1.6E-41 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CP478_RS18400 8aa030b74ddb95d52b63b7a55a1e371e 396 Gene3D G3DSA:3.20.20.70 7 395 5.1E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS15460 a6dea5e71967532b49cf9df62305e8d2 295 SUPERFAMILY SSF46785 1 82 1.36E-47 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15460 a6dea5e71967532b49cf9df62305e8d2 295 Pfam PF09407 AbiEi antitoxin C-terminal domain 85 237 1.6E-48 T 28-03-2018 IPR018547 AbiEi antitoxin C-terminal domain CP478_RS15460 a6dea5e71967532b49cf9df62305e8d2 295 SUPERFAMILY SSF160887 83 294 1.83E-111 T 28-03-2018 CP478_RS15460 a6dea5e71967532b49cf9df62305e8d2 295 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 9 73 1.8E-18 T 28-03-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin CP478_RS14020 7f329698f212b64b7ee40828257ae894 224 Gene3D G3DSA:3.30.70.100 11 118 2.0E-10 T 28-03-2018 CP478_RS14020 7f329698f212b64b7ee40828257ae894 224 Gene3D G3DSA:3.30.70.100 119 217 5.5E-5 T 28-03-2018 CP478_RS14020 7f329698f212b64b7ee40828257ae894 224 SUPERFAMILY SSF54909 124 195 4.56E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS14020 7f329698f212b64b7ee40828257ae894 224 SUPERFAMILY SSF54909 39 110 1.07E-7 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS14020 7f329698f212b64b7ee40828257ae894 224 Pfam PF03992 Antibiotic biosynthesis monooxygenase 25 84 1.6E-4 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 Gene3D G3DSA:3.60.21.10 164 529 3.8E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 SUPERFAMILY SSF49363 51 152 3.92E-21 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 Gene3D G3DSA:2.60.40.380 66 162 2.0E-13 T 28-03-2018 CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 Pfam PF00149 Calcineurin-like phosphoesterase 212 389 4.5E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 SUPERFAMILY SSF56300 165 447 1.05E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS14125 e885b638366008165fb0efef5d2561e9 529 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 67 149 7.3E-16 T 28-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CP478_RS15340 b7da3edb1dda0aa7ef263bbaa51aefbd 347 Pfam PF10056 Uncharacterized conserved protein (DUF2293) 257 343 3.7E-25 T 28-03-2018 IPR018744 Domain of unknown function DUF2293 CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 Gene3D G3DSA:2.160.10.10 61 175 1.3E-33 T 28-03-2018 CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 2.7E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 6.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 1.5E-76 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 SUPERFAMILY SSF51161 4 170 4.44E-56 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS12735 8d610b9c85829a96a31c9a862007a01b 229 Gene3D G3DSA:1.10.3130.10 1 60 7.9E-26 T 28-03-2018 CP478_RS15830 2e91ee0762988de149de124998127849 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 143 3.0E-38 T 28-03-2018 CP478_RS15830 2e91ee0762988de149de124998127849 503 SUPERFAMILY SSF52540 190 498 1.56E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15830 2e91ee0762988de149de124998127849 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 393 2.6E-84 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CP478_RS15830 2e91ee0762988de149de124998127849 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 497 2.3E-139 T 28-03-2018 IPR004482 Mg chelatase-related protein CP478_RS15830 2e91ee0762988de149de124998127849 503 Gene3D G3DSA:3.40.50.300 186 433 1.1E-23 T 28-03-2018 CP478_RS15830 2e91ee0762988de149de124998127849 503 Gene3D G3DSA:3.30.230.10 2 185 3.8E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS15830 2e91ee0762988de149de124998127849 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 401 497 5.6E-23 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CP478_RS15830 2e91ee0762988de149de124998127849 503 SMART SM00382 210 392 7.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS15830 2e91ee0762988de149de124998127849 503 SUPERFAMILY SSF54211 3 168 1.4E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS10165 9e605858ea6bb869b42fc10bc0838384 211 Gene3D G3DSA:1.10.340.30 41 164 8.6E-8 T 28-03-2018 CP478_RS10165 9e605858ea6bb869b42fc10bc0838384 211 SUPERFAMILY SSF48150 44 166 1.92E-6 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Gene3D G3DSA:1.20.140.10 209 372 1.3E-25 T 28-03-2018 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Gene3D G3DSA:2.40.110.10 111 208 8.8E-17 T 28-03-2018 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 SUPERFAMILY SSF56645 9 215 6.81E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 SUPERFAMILY SSF47203 215 371 1.42E-23 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 85 1.7E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 PIRSF PIRSF016578 3 372 3.3E-24 T 28-03-2018 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 111 199 1.3E-11 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Gene3D G3DSA:1.10.540.10 6 110 7.8E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS09170 61da57c5121df772630e145ac0b06a51 373 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 353 1.3E-14 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS18955 c187ca8242a72d84d169f3e40d1066cb 331 Gene3D G3DSA:3.90.25.10 186 331 2.4E-39 T 28-03-2018 CP478_RS18955 c187ca8242a72d84d169f3e40d1066cb 331 SUPERFAMILY SSF51735 1 322 2.73E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18955 c187ca8242a72d84d169f3e40d1066cb 331 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 6.2E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18955 c187ca8242a72d84d169f3e40d1066cb 331 Gene3D G3DSA:3.40.50.720 1 185 3.5E-40 T 28-03-2018 CP478_RS18955 c187ca8242a72d84d169f3e40d1066cb 331 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 6.1E-151 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 SUPERFAMILY SSF50129 310 360 1.6E-7 T 28-03-2018 IPR011032 GroES-like CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 Gene3D G3DSA:3.90.180.10 1 188 2.0E-50 T 28-03-2018 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 SMART SM00829 14 359 3.9E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 SUPERFAMILY SSF50129 4 186 4.87E-52 T 28-03-2018 IPR011032 GroES-like CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 1.4E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 1.5E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 Gene3D G3DSA:3.40.50.720 189 307 1.2E-20 T 28-03-2018 CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 SUPERFAMILY SSF51735 153 326 3.52E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12295 fa588ca087b69a8c5758282cccac5352 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 5.7E-213 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CP478_RS09485 ce764846ad06b4f1f0aec772d2d710a6 94 Pfam PF08962 Domain of unknown function (DUF1876) 11 90 6.7E-33 T 28-03-2018 IPR015057 Protein of unknown function DUF1876 CP478_RS09485 ce764846ad06b4f1f0aec772d2d710a6 94 SUPERFAMILY SSF143212 7 89 5.23E-33 T 28-03-2018 CP478_RS09485 ce764846ad06b4f1f0aec772d2d710a6 94 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 13 93 3.0E-40 T 28-03-2018 IPR015057 Protein of unknown function DUF1876 CP478_RS11905 59f476dd2bf0b3b5c18da090b3554dc7 385 Gene3D G3DSA:3.90.1720.10 268 385 6.9E-34 T 28-03-2018 CP478_RS11905 59f476dd2bf0b3b5c18da090b3554dc7 385 SUPERFAMILY SSF54001 267 384 7.19E-37 T 28-03-2018 CP478_RS11905 59f476dd2bf0b3b5c18da090b3554dc7 385 Pfam PF00877 NlpC/P60 family 285 370 1.2E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 Hamap MF_01220_B Uridylate kinase [pyrH]. 28 260 41.49 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 30 260 1.4E-84 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 SUPERFAMILY SSF53633 30 260 5.89E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 PIRSF PIRSF005650 26 261 6.4E-82 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 Pfam PF00696 Amino acid kinase family 32 239 1.5E-28 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CP478_RS15760 98a1bf05221b86cdfa253b1911d5b42c 261 Gene3D G3DSA:3.40.1160.10 8 261 1.7E-45 T 28-03-2018 CP478_RS14145 dc842983de8f63a96ed214ad12ea0deb 224 SUPERFAMILY SSF56281 5 220 2.49E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS14145 dc842983de8f63a96ed214ad12ea0deb 224 Gene3D G3DSA:3.60.15.10 1 223 9.2E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS14145 dc842983de8f63a96ed214ad12ea0deb 224 SMART SM00849 12 203 3.4E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS14145 dc842983de8f63a96ed214ad12ea0deb 224 Pfam PF00753 Metallo-beta-lactamase superfamily 9 203 1.3E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02690 95d69adef4933d046dfcb0b23eb60ec3 358 SUPERFAMILY SSF69593 98 350 2.22E-45 T 28-03-2018 CP478_RS02690 95d69adef4933d046dfcb0b23eb60ec3 358 Gene3D G3DSA:3.40.1130.10 102 354 1.1E-29 T 28-03-2018 CP478_RS02690 95d69adef4933d046dfcb0b23eb60ec3 358 SMART SM00563 144 263 1.0E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS02690 95d69adef4933d046dfcb0b23eb60ec3 358 PIRSF PIRSF016753 46 358 3.6E-119 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted CP478_RS02690 95d69adef4933d046dfcb0b23eb60ec3 358 Pfam PF01553 Acyltransferase 129 260 1.6E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS01355 76573e8e2aa764232da68e66e2d7e082 159 Gene3D G3DSA:2.60.40.790 9 158 2.6E-26 T 28-03-2018 IPR008978 HSP20-like chaperone CP478_RS01355 76573e8e2aa764232da68e66e2d7e082 159 Pfam PF00011 Hsp20/alpha crystallin family 47 157 3.2E-14 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CP478_RS01355 76573e8e2aa764232da68e66e2d7e082 159 SUPERFAMILY SSF49764 13 142 1.71E-25 T 28-03-2018 IPR008978 HSP20-like chaperone CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 Gene3D G3DSA:1.10.10.10 1080 1129 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 SMART SM00421 1067 1124 6.9E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1100 1112 6.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1084 1100 6.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1070 1084 6.5E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 Gene3D G3DSA:3.30.70.1230 54 222 1.3E-19 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00364 Disease resistance protein signature 261 276 2.2E-6 T 28-03-2018 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00364 Disease resistance protein signature 424 438 2.2E-6 T 28-03-2018 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 PRINTS PR00364 Disease resistance protein signature 330 344 2.2E-6 T 28-03-2018 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 SUPERFAMILY SSF48452 683 843 9.86E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 Gene3D G3DSA:1.25.40.10 685 1079 7.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 SUPERFAMILY SSF46894 1063 1128 1.05E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 Gene3D G3DSA:3.40.50.300 231 378 1.4E-12 T 28-03-2018 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1084 1111 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 SUPERFAMILY SSF52540 236 483 1.14E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 SUPERFAMILY SSF55073 53 227 3.14E-28 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS13605 f5216202d2c627bfbac35fd61cbbec40 1137 Pfam PF00196 Bacterial regulatory proteins, luxR family 1070 1122 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 Gene3D G3DSA:3.40.640.10 171 290 1.5E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 PIRSF PIRSF000521 5 135 1.1E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 PIRSF PIRSF000521 170 396 1.4E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 PIRSF PIRSF000521 127 161 0.81 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 Pfam PF00202 Aminotransferase class-III 22 392 2.5E-105 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 16 394 42.834 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 Gene3D G3DSA:3.90.1150.10 291 396 1.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 393 2.4E-154 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 Gene3D G3DSA:3.90.1150.10 3 169 4.5E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS09055 8fd6d2a3401694cabceaae2762c35052 400 SUPERFAMILY SSF53383 18 394 3.09E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS17730 88285d3741f5619158feb277f9c77263 295 SUPERFAMILY SSF52540 64 247 1.01E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17730 88285d3741f5619158feb277f9c77263 295 Gene3D G3DSA:3.40.50.300 6 275 3.0E-98 T 28-03-2018 CP478_RS17730 88285d3741f5619158feb277f9c77263 295 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 33 259 4.7E-111 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CP478_RS17730 88285d3741f5619158feb277f9c77263 295 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 33 259 2.2E-113 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CP478_RS17730 88285d3741f5619158feb277f9c77263 295 PIRSF PIRSF028756 5 289 1.2E-127 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 Gene3D G3DSA:3.40.50.20 1 94 2.4E-8 T 28-03-2018 CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 5 207 8.4E-52 T 28-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 Gene3D G3DSA:2.160.10.10 158 208 8.1E-12 T 28-03-2018 CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 141 4.0E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 160 193 1.7E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 Gene3D G3DSA:2.160.10.10 96 157 5.8E-13 T 28-03-2018 CP478_RS08245 806a153ca12d842715f2cb9f3af0940a 221 SUPERFAMILY SSF51161 3 206 6.24E-34 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS02835 1c8d152e03cea4fc9016756795958ae0 405 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 153 340 3.5E-11 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS02835 1c8d152e03cea4fc9016756795958ae0 405 SUPERFAMILY SSF52540 151 384 1.16E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02835 1c8d152e03cea4fc9016756795958ae0 405 Gene3D G3DSA:3.40.50.300 150 393 3.3E-29 T 28-03-2018 CP478_RS05995 39b1f627da10d639d472c6baeac316d1 853 SUPERFAMILY SSF140459 8 84 2.62E-25 T 28-03-2018 CP478_RS05995 39b1f627da10d639d472c6baeac316d1 853 Pfam PF00934 PE family 1 93 3.0E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05925 67caef45273da5b082458148289f3fa0 144 Pfam PF14155 Domain of unknown function (DUF4307) 23 133 4.5E-35 T 28-03-2018 IPR025443 Protein of unknown function DUF4307 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 411 504 6.4E-14 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 383 393 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 SUPERFAMILY SSF51905 290 354 4.14E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 SUPERFAMILY SSF51905 28 256 4.14E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 Pfam PF01266 FAD dependent oxidoreductase 28 363 1.2E-48 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 102 114 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 27 39 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 40 50 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 344 350 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 56 68 7.1E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 Gene3D G3DSA:3.50.50.60 3 98 4.0E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 32 49 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 Gene3D G3DSA:3.30.9.10 106 202 1.0E-9 T 28-03-2018 CP478_RS12235 a3274e1948d056bcc4e6a9c7f4cfbdb5 516 Gene3D G3DSA:3.30.9.10 203 351 3.3E-32 T 28-03-2018 CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 SUPERFAMILY SSF51735 12 264 5.37E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 Pfam PF00106 short chain dehydrogenase 15 216 4.9E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.3E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS12310 5db2898cc65b0d0dc09bf33f019c861e 317 Gene3D G3DSA:3.40.50.720 3 315 1.3E-60 T 28-03-2018 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 Hamap MF_00297 NADH pyrophosphatase [nudC]. 31 307 37.915 T 28-03-2018 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 137 167 5.1E-9 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 50 134 3.1E-6 T 28-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 Pfam PF00293 NUDIX domain 172 284 1.7E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 ProSitePatterns PS00893 Nudix box signature. 203 224 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 SUPERFAMILY SSF55811 123 288 9.75E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS17535 211ccf93309825d8be111f5b89cf6211 313 Gene3D G3DSA:3.90.79.10 169 313 1.3E-32 T 28-03-2018 CP478_RS19110 5182256527a36a75b48bdd5294da8cc5 564 Pfam PF02470 MlaD protein 39 114 1.9E-17 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS19110 5182256527a36a75b48bdd5294da8cc5 564 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 5.6E-85 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 Gene3D G3DSA:3.40.50.880 3 198 7.7E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 SUPERFAMILY SSF52317 4 194 2.36E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 Pfam PF01174 SNO glutamine amidotransferase family 8 194 1.8E-58 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 5 192 4.9E-68 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 6 193 36.039 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 ProSitePatterns PS01236 PdxT/SNO family family signature. 43 53 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14270 0a9d6ff86fd86e2739f4636d9f98c43a 198 PIRSF PIRSF005639 1 198 5.3E-72 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14900 3543934946815feac99e88a3c28be08f 165 Gene3D G3DSA:3.10.350.10 113 164 3.9E-5 T 28-03-2018 CP478_RS14900 3543934946815feac99e88a3c28be08f 165 Pfam PF01476 LysM domain 116 163 3.8E-8 T 28-03-2018 IPR018392 LysM domain CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PIRSF PIRSF000109 6 483 1.1E-201 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 SUPERFAMILY SSF48179 184 478 2.0E-119 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 186 474 5.2E-124 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 12 475 5.7E-221 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 Gene3D G3DSA:1.20.5.320 443 483 1.1E-17 T 28-03-2018 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 364 386 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 74 103 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 257 284 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 175 203 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 127 152 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 11 34 1.1E-80 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 181 2.8E-49 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 261 273 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 Gene3D G3DSA:3.40.50.720 10 187 4.2E-38 T 28-03-2018 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 Gene3D G3DSA:1.10.1040.10 188 442 1.7E-104 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 SUPERFAMILY SSF51735 11 184 1.68E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10030 53e4cfd09f5b5414c0e14deb0e56202f 483 SMART SM01350 186 475 9.6E-206 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS05400 47230954b79ebb904622e91852ac8035 325 Gene3D G3DSA:1.10.600.10 5 323 1.7E-73 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS05400 47230954b79ebb904622e91852ac8035 325 Pfam PF00348 Polyprenyl synthetase 37 274 6.1E-41 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CP478_RS05400 47230954b79ebb904622e91852ac8035 325 SUPERFAMILY SSF48576 13 321 4.32E-58 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS12410 6a5aa07f0c43dabd6d3bb1ba0c341431 431 Pfam PF07859 alpha/beta hydrolase fold 185 392 8.9E-20 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS12410 6a5aa07f0c43dabd6d3bb1ba0c341431 431 Gene3D G3DSA:3.40.50.1820 144 419 1.8E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12410 6a5aa07f0c43dabd6d3bb1ba0c341431 431 SUPERFAMILY SSF53474 161 394 1.2E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 SUPERFAMILY SSF53300 94 297 4.73E-30 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 Pfam PF07584 Aerotolerance regulator N-terminal 13 86 1.1E-5 T 28-03-2018 IPR024163 Aerotolerance regulator, N-terminal CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 SMART SM00327 96 274 8.5E-29 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 Pfam PF13519 von Willebrand factor type A domain 99 212 9.6E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 Hamap MF_01340 UPF0353 protein . 9 335 57.096 T 28-03-2018 IPR022933 Uncharacterised protein family UPF0353 CP478_RS08115 201f60e008f24c11aa18f1a44f1fead4 335 Gene3D G3DSA:3.40.50.410 92 307 6.9E-39 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 43 292 1.1E-46 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 325 574 2.6E-55 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 SUPERFAMILY SSF51445 1 324 2.11E-79 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 SUPERFAMILY SSF52279 555 577 4.58E-50 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 SUPERFAMILY SSF52279 325 527 4.58E-50 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Gene3D G3DSA:3.40.50.1700 318 574 9.9E-75 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 SMART SM01217 606 673 7.3E-22 T 28-03-2018 IPR026891 Fibronectin type III-like domain CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Pfam PF14310 Fibronectin type III-like domain 607 672 1.8E-16 T 28-03-2018 IPR026891 Fibronectin type III-like domain CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 PRINTS PR00133 Glycosyl hydrolase family 3 signature 43 59 1.4E-28 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 PRINTS PR00133 Glycosyl hydrolase family 3 signature 72 91 1.4E-28 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 PRINTS PR00133 Glycosyl hydrolase family 3 signature 219 237 1.4E-28 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 PRINTS PR00133 Glycosyl hydrolase family 3 signature 149 165 1.4E-28 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 PRINTS PR00133 Glycosyl hydrolase family 3 signature 118 134 1.4E-28 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Gene3D G3DSA:3.20.20.300 23 317 1.3E-85 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01015 d1a07ac83a04285cfbffccf164bda132 691 Gene3D G3DSA:2.60.40.10 575 687 4.3E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS03860 68603bd2c7db1505b42ef571405a6137 299 SUPERFAMILY SSF56436 3 295 5.27E-86 T 28-03-2018 IPR016187 C-type lectin fold CP478_RS03860 68603bd2c7db1505b42ef571405a6137 299 Gene3D G3DSA:3.90.1580.10 1 299 8.4E-86 T 28-03-2018 CP478_RS03860 68603bd2c7db1505b42ef571405a6137 299 Pfam PF03781 Sulfatase-modifying factor enzyme 1 3 294 1.8E-90 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 567 712 3.8E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 204 328 2.4E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:1.20.140.10 203 330 2.5E-28 T 28-03-2018 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 367 455 2.0E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.4E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 SUPERFAMILY SSF56645 381 580 1.03E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 SUPERFAMILY SSF47203 567 713 4.35E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:1.10.540.10 3 118 6.9E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:1.10.540.10 349 454 6.2E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 SUPERFAMILY SSF47203 205 343 1.32E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:1.20.140.10 555 720 1.6E-30 T 28-03-2018 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 SUPERFAMILY SSF56645 1 199 3.66E-28 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:2.40.110.10 455 554 9.9E-31 T 28-03-2018 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Gene3D G3DSA:2.40.110.10 140 202 0.22 T 28-03-2018 CP478_RS16750 3d451624790c06c87428b74b8eb5d7f1 721 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 461 555 1.8E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS14135 91382922cb079dfb6c674936772df960 300 PRINTS PR00412 Epoxide hydrolase signature 105 118 2.1E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14135 91382922cb079dfb6c674936772df960 300 PRINTS PR00412 Epoxide hydrolase signature 268 290 2.1E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14135 91382922cb079dfb6c674936772df960 300 PRINTS PR00412 Epoxide hydrolase signature 37 55 2.1E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14135 91382922cb079dfb6c674936772df960 300 Pfam PF00561 alpha/beta hydrolase fold 32 155 1.4E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14135 91382922cb079dfb6c674936772df960 300 Gene3D G3DSA:3.40.50.1820 3 299 7.2E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14135 91382922cb079dfb6c674936772df960 300 SUPERFAMILY SSF53474 11 294 2.67E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14135 91382922cb079dfb6c674936772df960 300 Hamap MF_01231 Haloalkane dehalogenase [dhaA]. 2 294 54.7 T 28-03-2018 IPR023594 Haloalkane dehalogenase, subfamily 2 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 Pfam PF00067 Cytochrome P450 304 392 3.6E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 Gene3D G3DSA:1.10.630.10 3 432 6.0E-58 T 28-03-2018 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 119 130 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 368 377 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 165 181 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 377 388 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 222 244 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 301 312 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 182 197 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 318 345 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 PRINTS PR00359 B-class P450 signature 346 361 1.5E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS19375 48a5269e9b49ed4ad80124e04dd960d8 433 SUPERFAMILY SSF48264 16 428 1.2E-77 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS14465 67dfedf0e75f8aefeab74a1048eec876 152 SUPERFAMILY SSF54593 5 118 2.89E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS14465 67dfedf0e75f8aefeab74a1048eec876 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 114 1.1E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS14465 67dfedf0e75f8aefeab74a1048eec876 152 Gene3D G3DSA:3.10.180.10 4 137 3.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS06320 00ca6432b44760205cf87e5cce262877 121 Gene3D G3DSA:1.10.10.10 4 94 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06320 00ca6432b44760205cf87e5cce262877 121 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 80 2.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS06320 00ca6432b44760205cf87e5cce262877 121 SMART SM00345 21 80 2.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS06320 00ca6432b44760205cf87e5cce262877 121 SUPERFAMILY SSF46785 11 90 2.38E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14330 719a3c613c17796765877efa2392ef70 461 Pfam PF00934 PE family 1 92 7.6E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS14330 719a3c613c17796765877efa2392ef70 461 SUPERFAMILY SSF140459 8 82 3.4E-20 T 28-03-2018 CP478_RS14330 719a3c613c17796765877efa2392ef70 461 PRINTS PR01228 Eggshell protein signature 248 258 2.7E-7 T 28-03-2018 CP478_RS14330 719a3c613c17796765877efa2392ef70 461 PRINTS PR01228 Eggshell protein signature 134 145 2.7E-7 T 28-03-2018 CP478_RS14330 719a3c613c17796765877efa2392ef70 461 PRINTS PR01228 Eggshell protein signature 221 236 2.7E-7 T 28-03-2018 CP478_RS14330 719a3c613c17796765877efa2392ef70 461 PRINTS PR01228 Eggshell protein signature 300 318 2.7E-7 T 28-03-2018 CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 SUPERFAMILY SSF109755 2 214 4.81E-51 T 28-03-2018 CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 Gene3D G3DSA:1.20.58.220 1 110 3.1E-17 T 28-03-2018 CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 PIRSF PIRSF003107 1 218 3.5E-46 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 Pfam PF01895 PhoU domain 123 204 4.1E-8 T 28-03-2018 IPR026022 PhoU domain CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 Pfam PF01895 PhoU domain 17 104 2.5E-14 T 28-03-2018 IPR026022 PhoU domain CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 210 5.3E-50 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CP478_RS18085 9f870c3db6bc7c92c14e460eb52e4e7c 221 Gene3D G3DSA:1.20.58.220 111 220 1.2E-14 T 28-03-2018 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 SUPERFAMILY SSF55347 175 453 1.6E-88 T 28-03-2018 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 Gene3D G3DSA:3.30.360.10 183 465 8.1E-101 T 28-03-2018 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 SUPERFAMILY SSF51735 11 181 5.81E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 10 457 1.5E-167 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 183 452 2.1E-86 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 170 176 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 136 149 2.0E-41 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 230 246 2.0E-41 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 307 333 2.0E-41 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 160 188 2.0E-41 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 212 229 2.0E-41 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 461 78.638 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 178 5.3E-41 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 Gene3D G3DSA:3.40.50.720 8 182 2.0E-49 T 28-03-2018 CP478_RS06140 1283db0efe61791ecd02c8ecdd507c11 466 PIRSF PIRSF000110 4 459 7.6E-148 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 Gene3D G3DSA:3.40.47.10 288 438 8.6E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 ProSitePatterns PS00099 Thiolases active site. 422 435 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 Gene3D G3DSA:3.40.47.10 7 287 1.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 SUPERFAMILY SSF53901 15 290 2.09E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 Pfam PF02803 Thiolase, C-terminal domain 291 439 1.1E-28 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 PIRSF PIRSF000429 9 440 5.1E-98 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 Pfam PF00108 Thiolase, N-terminal domain 15 283 3.9E-43 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 SUPERFAMILY SSF53901 291 439 5.28E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01315 07cbdf02968802033d090d66b384fd3f 440 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 439 2.8E-121 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 Gene3D G3DSA:1.20.1250.20 290 531 5.2E-28 T 28-03-2018 CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 Pfam PF07690 Major Facilitator Superfamily 50 443 2.1E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 43 525 4.8E-191 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 Gene3D G3DSA:1.20.1250.20 42 231 6.9E-31 T 28-03-2018 CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 SUPERFAMILY SSF103473 45 233 1.96E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 SUPERFAMILY SSF103473 281 453 1.96E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS04255 c87d433b1064e9075cbd7518686aef26 540 SUPERFAMILY SSF103473 501 531 1.96E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12465 b2d66d1656182e9260d5b34baab003bb 407 Gene3D G3DSA:3.90.1150.10 273 407 5.4E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS12465 b2d66d1656182e9260d5b34baab003bb 407 Gene3D G3DSA:3.40.640.10 43 272 8.4E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS12465 b2d66d1656182e9260d5b34baab003bb 407 SUPERFAMILY SSF53383 21 401 1.83E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS12465 b2d66d1656182e9260d5b34baab003bb 407 Pfam PF00155 Aminotransferase class I and II 81 396 2.7E-28 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS20160 77fb83e9b498bb858991923d38ffbae7 333 Pfam PF14258 Domain of unknown function (DUF4350) 5 72 1.3E-7 T 28-03-2018 IPR025646 Domain of unknown function DUF4350 CP478_RS20160 77fb83e9b498bb858991923d38ffbae7 333 Gene3D G3DSA:3.40.50.720 9 332 5.6E-4 T 28-03-2018 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.8E-40 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 Gene3D G3DSA:1.10.287.10 2 89 6.0E-35 T 28-03-2018 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 SUPERFAMILY SSF47060 3 89 1.97E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.283 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 SMART SM01387 8 88 8.2E-48 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 Pfam PF00312 Ribosomal protein S15 8 88 4.4E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15250 2f2709506a74d1cb9ab3fd4fb79cac38 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 6.0E-29 T 28-03-2018 CP478_RS10815 1317b99c40069537df466770265d7b92 199 Pfam PF01810 LysE type translocator 14 197 9.7E-43 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CP478_RS10815 1317b99c40069537df466770265d7b92 199 TIGRFAM TIGR00948 2a75: L-lysine exporter 15 189 5.6E-70 T 28-03-2018 IPR004777 L-lysine exporter/arginine exporter GO:0016021 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 SUPERFAMILY SSF54292 4 105 9.7E-28 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 Gene3D G3DSA:1.10.1060.10 106 243 5.0E-25 T 28-03-2018 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 SUPERFAMILY SSF46548 108 229 3.14E-30 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 110 1.3E-32 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 229 5.2E-79 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 Pfam PF13183 4Fe-4S dicluster domain 146 219 2.1E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS08510 72afedd37dbf9b9f0249690700b7e3d5 247 Gene3D G3DSA:3.10.20.30 1 105 7.1E-29 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 Gene3D G3DSA:3.40.50.720 52 247 2.9E-62 T 28-03-2018 CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 Gene3D G3DSA:3.40.50.720 9 51 2.9E-8 T 28-03-2018 CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 189 2.2E-5 T 28-03-2018 CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.5E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 5.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 5.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 243 1.1E-56 T 28-03-2018 CP478_RS08125 69d1f12edaa9b44dee5338edb61264c7 247 SUPERFAMILY SSF51735 16 245 8.18E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01790 f53fe3b7e2ddd8afb6108bb43171d034 171 Pfam PF00934 PE family 70 125 5.0E-16 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS01790 f53fe3b7e2ddd8afb6108bb43171d034 171 SUPERFAMILY SSF140459 69 117 4.45E-13 T 28-03-2018 CP478_RS00620 eb0b71c67ec9e3004038bd50cfcfb5ea 196 Gene3D G3DSA:3.40.50.10490 2 195 9.4E-37 T 28-03-2018 CP478_RS00620 eb0b71c67ec9e3004038bd50cfcfb5ea 196 SUPERFAMILY SSF53697 8 192 1.43E-49 T 28-03-2018 CP478_RS00620 eb0b71c67ec9e3004038bd50cfcfb5ea 196 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 191 36.174 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 CP478_RS00620 eb0b71c67ec9e3004038bd50cfcfb5ea 196 Pfam PF13580 SIS domain 33 148 1.3E-25 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CP478_RS08370 26db4ebedd481804889221725d7bf1f9 426 SUPERFAMILY SSF53756 1 413 2.2E-87 T 28-03-2018 CP478_RS08370 26db4ebedd481804889221725d7bf1f9 426 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 51 1.5E-8 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS08370 26db4ebedd481804889221725d7bf1f9 426 Gene3D G3DSA:3.40.50.2000 1 252 4.3E-39 T 28-03-2018 CP478_RS08370 26db4ebedd481804889221725d7bf1f9 426 Gene3D G3DSA:3.40.50.2000 253 400 9.9E-24 T 28-03-2018 CP478_RS01950 04d99703cf9ba9c3b51400acba3eacdc 376 Gene3D G3DSA:1.50.10.20 1 375 1.9E-42 T 28-03-2018 CP478_RS01950 04d99703cf9ba9c3b51400acba3eacdc 376 PIRSF PIRSF021505 1 375 2.1E-114 T 28-03-2018 IPR014512 Predicted O-glycosyl hydrolase CP478_RS01950 04d99703cf9ba9c3b51400acba3eacdc 376 SUPERFAMILY SSF48208 21 284 1.19E-23 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS01950 04d99703cf9ba9c3b51400acba3eacdc 376 Pfam PF03663 Glycosyl hydrolase family 76 9 351 1.5E-30 T 28-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 Gene3D G3DSA:3.40.250.10 161 284 1.5E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 SUPERFAMILY SSF52821 169 282 1.44E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 Pfam PF00581 Rhodanese-like domain 10 131 5.2E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 Pfam PF00581 Rhodanese-like domain 166 273 2.8E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 SMART SM00450 10 135 4.2E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 SMART SM00450 159 277 6.9E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 SUPERFAMILY SSF52821 4 152 6.42E-37 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 ProSitePatterns PS00683 Rhodanese C-terminal signature. 261 271 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS12445 7519c0a46732f008ead613efe12336b2 284 Gene3D G3DSA:3.40.250.10 1 156 7.6E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS02485 b11a3ce6f00b877fbc03a88f62a1fb59 264 Pfam PF01643 Acyl-ACP thioesterase 16 263 1.2E-69 T 28-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CP478_RS02485 b11a3ce6f00b877fbc03a88f62a1fb59 264 SUPERFAMILY SSF54637 155 230 1.5E-13 T 28-03-2018 IPR029069 HotDog domain CP478_RS02485 b11a3ce6f00b877fbc03a88f62a1fb59 264 Gene3D G3DSA:3.10.129.10 14 142 1.4E-13 T 28-03-2018 CP478_RS02485 b11a3ce6f00b877fbc03a88f62a1fb59 264 Gene3D G3DSA:3.10.129.10 157 253 2.6E-8 T 28-03-2018 CP478_RS02485 b11a3ce6f00b877fbc03a88f62a1fb59 264 SUPERFAMILY SSF54637 15 142 1.52E-20 T 28-03-2018 IPR029069 HotDog domain CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 SUPERFAMILY SSF56645 2 259 7.98E-50 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Gene3D G3DSA:1.20.140.10 243 410 6.4E-46 T 28-03-2018 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 402 5.4E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 SUPERFAMILY SSF47203 252 406 2.09E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 241 8.6E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 134 4.8E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Gene3D G3DSA:1.10.540.10 1 138 5.8E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 Gene3D G3DSA:2.40.110.10 139 242 5.5E-30 T 28-03-2018 CP478_RS15270 f47d72b5b2e35f36a20fe93460ddbdd4 410 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 142 154 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 Pfam PF13305 WHG domain 86 163 1.2E-12 T 28-03-2018 IPR025996 WHG domain CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 Gene3D G3DSA:1.10.260.40 34 61 4.2E-5 T 28-03-2018 CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 SUPERFAMILY SSF48498 80 184 2.08E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 7.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 Gene3D G3DSA:1.10.357.10 62 186 7.6E-20 T 28-03-2018 CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 Gene3D G3DSA:1.10.10.60 2 33 2.0E-8 T 28-03-2018 CP478_RS03680 d9d28b02c78134d0cffaa78612e5627c 196 SUPERFAMILY SSF46689 7 71 3.18E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS20520 fd7ec2a275209dc1ccf9a22b9edd714d 229 SUPERFAMILY SSF161098 11 196 1.14E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20520 fd7ec2a275209dc1ccf9a22b9edd714d 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 3.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS20520 fd7ec2a275209dc1ccf9a22b9edd714d 229 Gene3D G3DSA:1.10.3720.10 2 210 2.0E-21 T 28-03-2018 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 SUPERFAMILY SSF56645 86 299 1.44E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 Gene3D G3DSA:1.20.140.10 302 468 3.7E-37 T 28-03-2018 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 Gene3D G3DSA:2.40.110.10 190 293 2.1E-25 T 28-03-2018 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 309 461 2.8E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 193 290 1.1E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS20740 3fd46c95ebf87ca41cb2deac17b27bc9 593 SUPERFAMILY SSF47203 309 461 3.38E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS03360 22a2b291bbbc4b8ce5023418bd9ff5a3 246 Pfam PF09335 SNARE associated Golgi protein 71 188 2.7E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 SUPERFAMILY SSF53597 151 334 1.06E-45 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 Gene3D G3DSA:3.40.430.10 260 339 3.9E-17 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 Gene3D G3DSA:3.40.140.10 4 129 2.9E-26 T 28-03-2018 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 SUPERFAMILY SSF53927 12 139 1.46E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 106 1.1E-16 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 Gene3D G3DSA:3.40.430.10 130 259 3.4E-35 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 95 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 334 6.6E-93 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 Pfam PF01872 RibD C-terminal domain 154 334 2.8E-50 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 PIRSF PIRSF006769 245 339 4.7E-12 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CP478_RS07715 a5b2159bb363f270af3e18553584d1cc 339 PIRSF PIRSF006769 4 267 7.7E-89 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 Gene3D G3DSA:3.40.50.300 1 175 9.3E-36 T 28-03-2018 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 26.438 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 SUPERFAMILY SSF52540 2 165 6.19E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 Pfam PF01202 Shikimate kinase 11 166 2.4E-45 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 PRINTS PR01100 Shikimate kinase family signature 75 84 1.1E-19 T 28-03-2018 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 PRINTS PR01100 Shikimate kinase family signature 95 112 1.1E-19 T 28-03-2018 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 PRINTS PR01100 Shikimate kinase family signature 5 20 1.1E-19 T 28-03-2018 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 PRINTS PR01100 Shikimate kinase family signature 29 42 1.1E-19 T 28-03-2018 CP478_RS13915 4ff17001f8ba46d414a7b47c925165f4 176 PRINTS PR01100 Shikimate kinase family signature 57 65 1.1E-19 T 28-03-2018 CP478_RS18655 1e8d636a6686d9f0f1e5b18926784a66 136 Pfam PF01850 PIN domain 2 118 2.1E-13 T 28-03-2018 IPR002716 PIN domain CP478_RS18655 1e8d636a6686d9f0f1e5b18926784a66 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 129 13.311 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS18655 1e8d636a6686d9f0f1e5b18926784a66 136 SUPERFAMILY SSF88723 2 124 1.18E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18655 1e8d636a6686d9f0f1e5b18926784a66 136 Gene3D G3DSA:3.40.50.1010 1 130 1.6E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 SMART SM00895 103 224 2.1E-7 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 SUPERFAMILY SSF48008 101 230 2.88E-10 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 Gene3D G3DSA:1.20.120.530 94 236 3.6E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 SUPERFAMILY SSF46785 4 78 1.07E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 7.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 7.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 SMART SM00345 15 74 3.7E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 Pfam PF07729 FCD domain 104 223 5.4E-9 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 5.2E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS03140 8db5ff396bd11f054113ded7ba56e272 240 Gene3D G3DSA:1.10.10.10 1 76 5.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.2E-54 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Gene3D G3DSA:4.10.950.10 198 273 2.6E-30 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.333 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 SUPERFAMILY SSF50104 127 271 1.99E-55 T 28-03-2018 IPR008991 Translation protein SH3-like domain CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Gene3D G3DSA:2.40.50.140 1 115 7.0E-46 T 28-03-2018 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Gene3D G3DSA:2.30.30.30 120 196 1.4E-28 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 SMART SM01383 42 119 7.7E-42 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 4.6E-130 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 SMART SM01382 125 253 1.2E-87 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 SUPERFAMILY SSF50249 2 126 6.51E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 8.0E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03820 72dd3ab0083911ea8f6c5e45e75104aa 280 PIRSF PIRSF002158 4 275 1.3E-93 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 SUPERFAMILY SSF55729 24 39 8.19E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 SUPERFAMILY SSF55729 97 212 8.19E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 SUPERFAMILY SSF56719 18 104 2.88E-5 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 Gene3D G3DSA:1.10.268.10 12 98 2.5E-10 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 Gene3D G3DSA:3.40.630.30 99 235 5.5E-14 T 28-03-2018 CP478_RS03950 dc4f4745712f6706bbd1b87b724b6c0b 242 Pfam PF13302 Acetyltransferase (GNAT) domain 114 212 6.5E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS07955 5331b8fa90d7e7c73dcd16f1b6129e74 1329 Gene3D G3DSA:1.10.287.1060 1 101 2.7E-4 T 28-03-2018 CP478_RS07955 5331b8fa90d7e7c73dcd16f1b6129e74 1329 Pfam PF00934 PE family 1 92 5.5E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS07955 5331b8fa90d7e7c73dcd16f1b6129e74 1329 SUPERFAMILY SSF140459 8 83 4.45E-25 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 SUPERFAMILY SSF56784 295 584 6.07E-37 T 28-03-2018 IPR023214 HAD-like domain CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 SUPERFAMILY SSF81665 6 101 9.55E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 SUPERFAMILY SSF81665 199 293 9.55E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 SUPERFAMILY SSF81665 583 789 9.55E-62 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 Gene3D G3DSA:1.20.1110.10 457 788 5.7E-47 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 319 1.0E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 508 611 3.5E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 301 307 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 Gene3D G3DSA:2.70.150.10 2 197 2.4E-27 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 Pfam PF00702 haloacid dehalogenase-like hydrolase 295 548 2.7E-19 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 Gene3D G3DSA:3.40.1110.10 256 453 2.7E-19 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 534 550 2.0E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 506 522 2.0E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 399 417 2.0E-6 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 468 2.5E-23 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 2.5E-23 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 2.5E-23 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 2.5E-23 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 148 162 2.5E-23 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 Pfam PF00122 E1-E2 ATPase 103 277 1.4E-40 T 28-03-2018 CP478_RS04950 8edf4d3eac40761ee72e265832710a58 797 SUPERFAMILY SSF81653 104 195 1.57E-19 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 262 272 - T 28-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 ProSitePatterns PS00436 Peroxidases active site signature. 99 110 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 76 101 3.7E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 270 293 3.7E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 61 74 3.7E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 484 510 3.7E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 35 57 3.7E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Gene3D G3DSA:1.10.520.10 65 223 5.7E-38 T 28-03-2018 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Pfam PF00141 Peroxidase 406 713 1.7E-37 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Pfam PF00141 Peroxidase 91 397 3.6E-48 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Gene3D G3DSA:1.10.520.10 450 604 2.9E-31 T 28-03-2018 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00458 Haem peroxidase superfamily signature 321 336 1.0E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00458 Haem peroxidase superfamily signature 262 277 1.0E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00458 Haem peroxidase superfamily signature 177 189 1.0E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00458 Haem peroxidase superfamily signature 159 176 1.0E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 PRINTS PR00458 Haem peroxidase superfamily signature 99 113 1.0E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 SUPERFAMILY SSF48113 26 433 4.86E-155 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Gene3D G3DSA:1.10.420.10 605 715 6.4E-32 T 28-03-2018 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Gene3D G3DSA:1.10.420.10 236 401 9.1E-33 T 28-03-2018 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 24 739 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 SUPERFAMILY SSF48113 435 739 1.47E-105 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CP478_RS10385 260e6191c4d4cecbef13d23ae747b2cc 740 Hamap MF_01961 Catalase-peroxidase [katG]. 15 740 40.923 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 SUPERFAMILY SSF51905 148 347 1.1E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 SUPERFAMILY SSF51905 1 218 8.12E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 Pfam PF00743 Flavin-binding monooxygenase-like 76 349 1.1E-13 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 61 9.4E-7 T 28-03-2018 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 Gene3D G3DSA:3.50.50.60 169 448 3.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16865 8dcf0cd9a3595b1c61024374c56a7941 495 Gene3D G3DSA:3.50.50.60 4 168 1.3E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07155 3e1c3d37b2f1578ddce2a562c6faf2af 171 SUPERFAMILY SSF81573 87 145 3.66E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS07155 3e1c3d37b2f1578ddce2a562c6faf2af 171 Pfam PF00430 ATP synthase B/B' CF(0) 30 160 1.0E-32 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CP478_RS07155 3e1c3d37b2f1578ddce2a562c6faf2af 171 Gene3D G3DSA:1.20.5.620 76 146 5.4E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS07155 3e1c3d37b2f1578ddce2a562c6faf2af 171 Hamap MF_01398 ATP synthase subunit b [atpF]. 19 162 11.328 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CP478_RS00640 77907ff45dfa18d929374c9da0045523 251 SUPERFAMILY SSF141523 128 249 1.1E-30 T 28-03-2018 CP478_RS00640 77907ff45dfa18d929374c9da0045523 251 Pfam PF03734 L,D-transpeptidase catalytic domain 129 249 2.6E-19 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CP478_RS00640 77907ff45dfa18d929374c9da0045523 251 Gene3D G3DSA:2.40.440.10 120 250 5.4E-27 T 28-03-2018 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 Gene3D G3DSA:3.40.50.720 2 49 6.4E-8 T 28-03-2018 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 Gene3D G3DSA:3.40.50.720 50 247 5.6E-64 T 28-03-2018 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 1.8E-65 T 28-03-2018 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 1.9E-5 T 28-03-2018 CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07405 f9f307eccfb2c0db6fbf1825daf76ab5 247 SUPERFAMILY SSF51735 8 246 3.12E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Pfam PF08544 GHMP kinases C terminal 262 339 1.4E-12 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Gene3D G3DSA:3.30.70.890 189 361 1.8E-44 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Pfam PF00288 GHMP kinases N terminal domain 95 160 8.6E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 TIGRFAM TIGR00131 gal_kin: galactokinase 6 336 1.2E-70 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 SUPERFAMILY SSF55060 187 360 1.04E-43 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00959 Mevalonate kinase family signature 308 325 2.0E-35 T 28-03-2018 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00959 Mevalonate kinase family signature 98 120 2.0E-35 T 28-03-2018 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00959 Mevalonate kinase family signature 7 31 2.0E-35 T 28-03-2018 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00959 Mevalonate kinase family signature 141 160 2.0E-35 T 28-03-2018 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 SUPERFAMILY SSF54211 3 182 3.87E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Gene3D G3DSA:3.30.230.10 2 188 7.6E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00473 Galactokinase signature 71 82 2.2E-21 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00473 Galactokinase signature 91 109 2.2E-21 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00473 Galactokinase signature 9 27 2.2E-21 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PRINTS PR00473 Galactokinase signature 245 259 2.2E-21 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 PIRSF PIRSF000530 1 363 9.1E-103 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Hamap MF_00246 Galactokinase [galK]. 7 361 39.814 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 Pfam PF10509 Galactokinase galactose-binding signature 6 38 4.0E-15 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS03330 3c36c89daf5814882678701c61e8972a 363 ProSitePatterns PS00106 Galactokinase signature. 9 20 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 SUPERFAMILY SSF117916 20 109 2.98E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 Pfam PF01883 Iron-sulfur cluster assembly protein 20 92 1.9E-17 T 28-03-2018 IPR002744 MIP18 family-like CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 Hamap MF_02040 Iron-sulfur cluster carrier protein. 117 372 32.818 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 Gene3D G3DSA:3.40.50.300 103 379 2.4E-52 T 28-03-2018 CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 Gene3D G3DSA:3.30.300.130 16 102 1.3E-17 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 ProSitePatterns PS01215 Mrp family signature. 230 246 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 126 370 5.6E-86 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CP478_RS06735 ecb188b7ba23379bdf3d85f6c09abd22 390 SUPERFAMILY SSF52540 126 374 4.41E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Pfam PF01469 Pentapeptide repeats (8 copies) 379 418 3.0E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Pfam PF01469 Pentapeptide repeats (8 copies) 311 348 2.4E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Pfam PF01469 Pentapeptide repeats (8 copies) 339 378 1.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Pfam PF01469 Pentapeptide repeats (8 copies) 409 446 2.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 SUPERFAMILY SSF140459 2 172 4.97E-56 T 28-03-2018 CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Gene3D G3DSA:1.10.287.1060 18 111 1.3E-5 T 28-03-2018 CP478_RS09560 b455a3edeb86440032aa6dc3c3b0f8d2 1053 Pfam PF00823 PPE family 5 161 9.2E-56 T 28-03-2018 IPR000030 PPE family CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 SUPERFAMILY SSF51679 4 333 8.77E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 Hamap MF_02123 F420-dependent glucose-6-phosphate dehydrogenase [fgd]. 3 335 69.857 T 28-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 Pfam PF00296 Luciferase-like monooxygenase 11 307 3.6E-65 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 Gene3D G3DSA:3.20.20.30 1 336 4.7E-76 T 28-03-2018 CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 6 333 3.0E-75 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CP478_RS02170 158feeb5373502950be9b8eb47193ccb 336 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 3 333 3.1E-222 T 28-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CP478_RS04990 46efc23d57005cb373cff1e2444733f1 423 Pfam PF00823 PPE family 6 161 5.5E-60 T 28-03-2018 IPR000030 PPE family CP478_RS04990 46efc23d57005cb373cff1e2444733f1 423 Gene3D G3DSA:1.10.287.1060 20 102 1.8E-8 T 28-03-2018 CP478_RS04990 46efc23d57005cb373cff1e2444733f1 423 SUPERFAMILY SSF140459 2 171 6.28E-61 T 28-03-2018 CP478_RS04990 46efc23d57005cb373cff1e2444733f1 423 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 319 395 3.6E-14 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS01395 5e66cb9e21b9ba9c1df61fbde35aeaf7 151 SUPERFAMILY SSF48498 37 147 4.45E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01395 5e66cb9e21b9ba9c1df61fbde35aeaf7 151 Gene3D G3DSA:1.10.357.10 20 148 4.6E-22 T 28-03-2018 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 19 575 45.592 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 137 147 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 483 494 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 SUPERFAMILY SSF52016 397 574 5.41E-54 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 SUPERFAMILY SSF143975 10 396 9.29E-137 T 28-03-2018 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 Pfam PF00920 Dehydratase family 49 572 1.2E-206 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CP478_RS01035 d0dbb479b299aef64bb347591e4b64ac 575 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 33 573 1.9E-214 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CP478_RS10180 8a7f7e4c5dba0206015630ab938c13fb 145 SUPERFAMILY SSF140736 6 143 8.24E-58 T 28-03-2018 IPR014937 Protein of unknown function DUF1810 CP478_RS10180 8a7f7e4c5dba0206015630ab938c13fb 145 PIRSF PIRSF008546 3 145 1.7E-72 T 28-03-2018 IPR014937 Protein of unknown function DUF1810 CP478_RS10180 8a7f7e4c5dba0206015630ab938c13fb 145 Pfam PF08837 Protein of unknown function (DUF1810) 8 142 1.9E-55 T 28-03-2018 IPR014937 Protein of unknown function DUF1810 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 SUPERFAMILY SSF56801 11 130 3.4E-79 T 28-03-2018 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 SUPERFAMILY SSF56801 183 445 3.4E-79 T 28-03-2018 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 Pfam PF00501 AMP-binding enzyme 17 312 3.7E-62 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 ProSitePatterns PS00455 Putative AMP-binding domain signature. 27 38 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 Gene3D G3DSA:2.30.38.10 234 306 2.6E-18 T 28-03-2018 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 Gene3D G3DSA:3.30.300.30 308 444 1.7E-10 T 28-03-2018 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 Gene3D G3DSA:3.40.50.980 4 33 5.8E-10 T 28-03-2018 CP478_RS08490 a0d411c97610a67649341c71930f0cb7 462 Gene3D G3DSA:3.40.50.980 34 233 1.6E-40 T 28-03-2018 CP478_RS09660 78a40a9c230a1fbeeec5d18b60907f69 103 SMART SM01012 15 70 1.4E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CP478_RS09660 78a40a9c230a1fbeeec5d18b60907f69 103 Pfam PF03861 ANTAR domain 27 70 4.3E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CP478_RS09660 78a40a9c230a1fbeeec5d18b60907f69 103 PIRSF PIRSF010636 3 103 1.2E-34 T 28-03-2018 IPR024189 ANTAR transcription anti-termination regulator CP478_RS09660 78a40a9c230a1fbeeec5d18b60907f69 103 Gene3D G3DSA:1.10.10.10 23 71 3.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13200 91d6ee7d664e564f105f0e3cb08453a2 247 Gene3D G3DSA:3.40.50.1110 2 239 7.5E-25 T 28-03-2018 CP478_RS13200 91d6ee7d664e564f105f0e3cb08453a2 247 SUPERFAMILY SSF52266 9 93 1.67E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS13200 91d6ee7d664e564f105f0e3cb08453a2 247 SUPERFAMILY SSF52266 137 237 1.67E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS13200 91d6ee7d664e564f105f0e3cb08453a2 247 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 16 226 7.2E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Gene3D G3DSA:3.40.50.980 195 363 4.3E-33 T 28-03-2018 CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 SUPERFAMILY SSF56801 31 551 2.62E-131 T 28-03-2018 CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 542 6.7E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Pfam PF00501 AMP-binding enzyme 48 457 2.2E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Gene3D G3DSA:2.30.38.10 377 451 6.0E-21 T 28-03-2018 CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Gene3D G3DSA:3.30.300.30 452 552 4.1E-18 T 28-03-2018 CP478_RS12995 9e498a8c6ef5c620de6ab24d5b1fdd5d 565 Gene3D G3DSA:3.40.50.980 37 194 7.2E-37 T 28-03-2018 CP478_RS04995 7721862028ddec345a9827bbe581d764 99 SUPERFAMILY SSF140459 8 79 1.05E-17 T 28-03-2018 CP478_RS04995 7721862028ddec345a9827bbe581d764 99 Pfam PF00934 PE family 1 92 2.1E-26 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS20055 ce33aadfcefedf6f164e8ab08d8afcab 227 Pfam PF00578 AhpC/TSA family 101 206 6.7E-10 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS20055 ce33aadfcefedf6f164e8ab08d8afcab 227 Gene3D G3DSA:3.40.30.10 86 224 2.5E-17 T 28-03-2018 CP478_RS20055 ce33aadfcefedf6f164e8ab08d8afcab 227 ProSitePatterns PS00194 Thioredoxin family active site. 118 136 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CP478_RS20055 ce33aadfcefedf6f164e8ab08d8afcab 227 SUPERFAMILY SSF52833 102 211 2.3E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS05245 079eb11eecd6df1eade06fb0a5f860d4 127 Pfam PF01850 PIN domain 2 115 3.2E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS05245 079eb11eecd6df1eade06fb0a5f860d4 127 SUPERFAMILY SSF88723 1 125 3.92E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS05245 079eb11eecd6df1eade06fb0a5f860d4 127 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 123 14.002 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS05245 079eb11eecd6df1eade06fb0a5f860d4 127 Gene3D G3DSA:3.40.50.1010 1 127 5.2E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS12425 8e515c5702be056f6374e2e2e8d965d3 542 Pfam PF00999 Sodium/hydrogen exchanger family 19 417 1.6E-74 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CP478_RS12425 8e515c5702be056f6374e2e2e8d965d3 542 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 17 537 1.9E-247 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CP478_RS07670 d86f7cd55098039a5a2b6ab5314b43fa 320 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 159 171 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site CP478_RS07670 d86f7cd55098039a5a2b6ab5314b43fa 320 Pfam PF07859 alpha/beta hydrolase fold 87 294 1.1E-71 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS07670 d86f7cd55098039a5a2b6ab5314b43fa 320 Gene3D G3DSA:3.40.50.1820 9 318 7.9E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07670 d86f7cd55098039a5a2b6ab5314b43fa 320 SUPERFAMILY SSF53474 46 308 2.17E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07670 d86f7cd55098039a5a2b6ab5314b43fa 320 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 87 103 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CP478_RS05140 483897a5e87922705496b987b8171682 346 SUPERFAMILY SSF51905 115 194 2.27E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS05140 483897a5e87922705496b987b8171682 346 SUPERFAMILY SSF51905 30 134 9.73E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS05140 483897a5e87922705496b987b8171682 346 Gene3D G3DSA:3.50.50.60 27 235 1.1E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS05140 483897a5e87922705496b987b8171682 346 Pfam PF16170 Domain of unknown function (DUF4873) 250 337 3.1E-29 T 28-03-2018 IPR032371 Domain of unknown function DUF4873 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 SMART SM00893 4 193 3.2E-27 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 Gene3D G3DSA:3.40.50.620 2 184 2.0E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 PIRSF PIRSF000089 1 318 1.9E-103 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 SUPERFAMILY SSF52402 4 184 6.2E-39 T 28-03-2018 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 257 283 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 SUPERFAMILY SSF52467 193 313 1.64E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 Gene3D G3DSA:3.40.50.1220 189 318 1.8E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 194 276 2.5E-35 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CP478_RS16565 1fef3d54fc3eaf374f28be91b62bf4d3 318 Pfam PF01012 Electron transfer flavoprotein domain 4 173 2.0E-28 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 SMART SM00518 1 181 2.4E-22 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 Gene3D G3DSA:3.20.20.150 2 180 5.9E-33 T 28-03-2018 CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 89 96 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 Pfam PF01261 Xylose isomerase-like TIM barrel 5 145 8.3E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 SUPERFAMILY SSF51658 2 179 1.44E-42 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CP478_RS03625 f6f4d0d1d1236b44161573d7be16e401 183 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 121 137 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CP478_RS08810 76fec3328d9c0df9f53d82de88b0f0e3 272 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 260 34.082 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CP478_RS08810 76fec3328d9c0df9f53d82de88b0f0e3 272 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 258 2.3E-78 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CP478_RS08810 76fec3328d9c0df9f53d82de88b0f0e3 272 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 54 71 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CP478_RS08810 76fec3328d9c0df9f53d82de88b0f0e3 272 Gene3D G3DSA:3.20.20.70 3 267 3.7E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08810 76fec3328d9c0df9f53d82de88b0f0e3 272 SUPERFAMILY SSF51366 15 260 1.41E-77 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SMART SM00065 28 181 3.7E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SUPERFAMILY SSF55781 31 183 1.52E-14 T 28-03-2018 IPR029016 GAF domain-like CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Gene3D G3DSA:3.30.70.270 183 350 1.2E-51 T 28-03-2018 CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Gene3D G3DSA:3.30.450.40 11 182 3.0E-13 T 28-03-2018 IPR029016 GAF domain-like CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Pfam PF00990 Diguanylate cyclase, GGDEF domain 184 338 4.3E-39 T 28-03-2018 IPR000160 GGDEF domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SMART SM00267 173 343 9.0E-62 T 28-03-2018 IPR000160 GGDEF domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Gene3D G3DSA:3.20.20.450 351 611 4.6E-90 T 28-03-2018 IPR001633 EAL domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SUPERFAMILY SSF55073 189 344 1.96E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Pfam PF13185 GAF domain 27 170 1.1E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SMART SM00052 353 600 9.5E-122 T 28-03-2018 IPR001633 EAL domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 Pfam PF00563 EAL domain 361 595 3.5E-67 T 28-03-2018 IPR001633 EAL domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 182 341 3.8E-33 T 28-03-2018 IPR000160 GGDEF domain CP478_RS07430 4c4085cffa7f46144008168936c7fbe8 623 SUPERFAMILY SSF141868 360 609 9.55E-82 T 28-03-2018 IPR001633 EAL domain CP478_RS15810 253d0d32573df5ae5610d1570650916f 325 Pfam PF00296 Luciferase-like monooxygenase 27 264 6.4E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS15810 253d0d32573df5ae5610d1570650916f 325 SUPERFAMILY SSF51679 12 317 1.85E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS15810 253d0d32573df5ae5610d1570650916f 325 Gene3D G3DSA:3.20.20.30 1 323 2.0E-48 T 28-03-2018 CP478_RS15810 253d0d32573df5ae5610d1570650916f 325 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 13 323 1.2E-123 T 28-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted CP478_RS06775 75bb46cebec07adc216e2bfb067dcf9c 274 Gene3D G3DSA:1.10.3720.10 7 265 2.2E-43 T 28-03-2018 CP478_RS06775 75bb46cebec07adc216e2bfb067dcf9c 274 SUPERFAMILY SSF161098 6 274 4.03E-70 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS06775 75bb46cebec07adc216e2bfb067dcf9c 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 266 1.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 SMART SM00357 3 65 6.6E-21 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 PRINTS PR00050 Cold shock protein signature 4 19 6.4E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 PRINTS PR00050 Cold shock protein signature 38 56 6.4E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 PRINTS PR00050 Cold shock protein signature 24 33 6.4E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 SUPERFAMILY SSF50249 2 68 8.81E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 Gene3D G3DSA:2.40.50.140 2 73 3.3E-18 T 28-03-2018 CP478_RS04750 955b5f29a6c9d36fcdf7f88e19f0d65c 135 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 3.4E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 Gene3D G3DSA:2.30.38.10 381 460 7.7E-19 T 28-03-2018 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 SUPERFAMILY SSF56801 5 572 6.54E-92 T 28-03-2018 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 Gene3D G3DSA:3.30.300.30 461 571 4.9E-16 T 28-03-2018 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 Gene3D G3DSA:3.40.50.980 173 362 1.6E-26 T 28-03-2018 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 Pfam PF00501 AMP-binding enzyme 14 467 3.5E-70 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS16065 b25e01926ebafa54379a74f6d562b2cf 580 Gene3D G3DSA:3.40.50.980 2 172 5.2E-28 T 28-03-2018 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 34.96 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 Gene3D G3DSA:3.40.50.1470 1 191 7.9E-72 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 189 8.2E-59 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 4.1E-56 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CP478_RS05550 46992d5434b83f18aa2eb9059bfb5174 191 SUPERFAMILY SSF53178 5 189 1.57E-64 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CP478_RS09845 ca289e72df0b512ee7bbcbbfefbed9bd 409 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 312 382 4.1E-9 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09845 ca289e72df0b512ee7bbcbbfefbed9bd 409 Gene3D G3DSA:1.10.287.1060 22 105 5.6E-6 T 28-03-2018 CP478_RS09845 ca289e72df0b512ee7bbcbbfefbed9bd 409 SUPERFAMILY SSF140459 2 174 2.88E-66 T 28-03-2018 CP478_RS09845 ca289e72df0b512ee7bbcbbfefbed9bd 409 Pfam PF00823 PPE family 5 161 3.2E-64 T 28-03-2018 IPR000030 PPE family CP478_RS17740 68ca85499ab3cb29ad479ca9b20a7901 271 SUPERFAMILY SSF52777 29 151 9.45E-7 T 28-03-2018 CP478_RS17740 68ca85499ab3cb29ad479ca9b20a7901 271 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 270 6.2E-88 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 191 1.2E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 Gene3D G3DSA:3.40.50.1000 1 202 1.0E-25 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 185 1.3E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 Pfam PF00702 haloacid dehalogenase-like hydrolase 3 185 3.2E-13 T 28-03-2018 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 193 2.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 103 116 2.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18490 50b89cff4cc5227549182f9608587bae 217 SUPERFAMILY SSF56784 3 207 1.43E-40 T 28-03-2018 IPR023214 HAD-like domain CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 9 299 53.657 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 SUPERFAMILY SSF51366 23 272 1.79E-58 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 Gene3D G3DSA:3.20.20.70 23 276 3.3E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 PIRSF PIRSF029271 3 299 2.2E-148 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 14 299 3.2E-142 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 ProSitePatterns PS01235 PdxS/SNZ family signature. 210 228 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS14280 0df161ceb525d8972dd9aa0b7b9ea024 299 Pfam PF01680 SOR/SNZ family 12 217 2.2E-106 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CP478_RS03730 d3bc81221e9426a725ea520bede1881f 349 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 10 348 1.7E-111 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CP478_RS03730 d3bc81221e9426a725ea520bede1881f 349 PIRSF PIRSF012608 1 349 6.2E-144 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CP478_RS01975 56dd23d63e75a13c96987ecff0c3c78f 298 Pfam PF07728 AAA domain (dynein-related subfamily) 37 191 9.9E-11 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CP478_RS01975 56dd23d63e75a13c96987ecff0c3c78f 298 Gene3D G3DSA:3.40.50.300 6 225 1.0E-26 T 28-03-2018 CP478_RS01975 56dd23d63e75a13c96987ecff0c3c78f 298 SUPERFAMILY SSF52540 112 268 2.65E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01975 56dd23d63e75a13c96987ecff0c3c78f 298 SUPERFAMILY SSF52540 28 85 2.65E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01975 56dd23d63e75a13c96987ecff0c3c78f 298 SMART SM00382 34 203 8.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS06100 b852d64be2ca5cae7b68db569d9fe3ac 65 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 42 2.0E-12 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS05970 d4b4b9311b2b3eb2a7b307fda27c8c84 144 SUPERFAMILY SSF140459 8 83 2.09E-21 T 28-03-2018 CP478_RS05970 d4b4b9311b2b3eb2a7b307fda27c8c84 144 Pfam PF00934 PE family 1 87 5.4E-28 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05100 a330fb975c156c7d119c6a316419d882 338 Gene3D G3DSA:1.10.3720.10 17 332 6.1E-28 T 28-03-2018 CP478_RS05100 a330fb975c156c7d119c6a316419d882 338 SUPERFAMILY SSF161098 22 38 9.16E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05100 a330fb975c156c7d119c6a316419d882 338 SUPERFAMILY SSF161098 65 321 9.16E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05100 a330fb975c156c7d119c6a316419d882 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 328 6.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS05100 a330fb975c156c7d119c6a316419d882 338 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 327 2.5E-99 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CP478_RS20570 b296fb66894b16743c7d8643110e5dd7 314 Gene3D G3DSA:3.40.50.150 1 301 1.3E-57 T 28-03-2018 CP478_RS20570 b296fb66894b16743c7d8643110e5dd7 314 SUPERFAMILY SSF53335 15 309 1.05E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20570 b296fb66894b16743c7d8643110e5dd7 314 Pfam PF04072 Leucine carboxyl methyltransferase 19 204 7.5E-62 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS20570 b296fb66894b16743c7d8643110e5dd7 314 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 291 7.2E-95 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 SUPERFAMILY SSF47203 216 341 3.87E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 375 465 4.7E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 100 6.6E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 SUPERFAMILY SSF56645 366 586 8.12E-55 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 469 557 9.6E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 SUPERFAMILY SSF47203 575 727 3.22E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:2.40.110.10 468 563 5.3E-31 T 28-03-2018 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 SUPERFAMILY SSF56645 1 202 3.66E-21 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:1.10.540.10 348 467 3.4E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:1.10.540.10 1 112 4.2E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:1.20.140.10 564 731 7.3E-30 T 28-03-2018 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:2.40.110.10 113 204 0.2 T 28-03-2018 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Gene3D G3DSA:1.20.140.10 205 337 4.1E-33 T 28-03-2018 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 575 725 7.2E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS01460 caa47935ccd2d1ed4bb2ed78c270b4d7 731 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 217 338 3.9E-24 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 469 504 7.6E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 206 240 1.1E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 360 396 2.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 428 466 6.2E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 281 319 1.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF01469 Pentapeptide repeats (8 copies) 241 280 7.9E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Pfam PF00823 PPE family 6 166 2.2E-55 T 28-03-2018 IPR000030 PPE family CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 Gene3D G3DSA:1.10.287.1060 21 114 9.8E-4 T 28-03-2018 CP478_RS12855 b00dac4101b5295df7275e1c22f439b8 615 SUPERFAMILY SSF140459 3 175 3.14E-57 T 28-03-2018 CP478_RS19630 a3accc925c83a0ef9f8874d1e49c3633 452 Gene3D G3DSA:3.40.710.10 149 451 4.1E-23 T 28-03-2018 CP478_RS19630 a3accc925c83a0ef9f8874d1e49c3633 452 Pfam PF13354 Beta-lactamase enzyme family 182 391 6.6E-23 T 28-03-2018 CP478_RS19630 a3accc925c83a0ef9f8874d1e49c3633 452 SUPERFAMILY SSF56601 52 288 1.21E-40 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS19630 a3accc925c83a0ef9f8874d1e49c3633 452 SUPERFAMILY SSF56601 341 448 1.21E-40 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Pfam PF07732 Multicopper oxidase 83 182 5.3E-27 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Gene3D G3DSA:2.60.40.420 65 185 9.3E-30 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Pfam PF00394 Multicopper oxidase 190 349 1.5E-25 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 CP478_RS04620 c301f6a1724881ea49278258c839baba 504 SUPERFAMILY SSF49503 60 184 9.59E-33 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Gene3D G3DSA:2.60.40.420 186 368 1.4E-38 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 SUPERFAMILY SSF49503 382 499 1.46E-31 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Gene3D G3DSA:2.60.40.420 369 502 3.8E-33 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 ProSitePatterns PS00079 Multicopper oxidases signature 1. 480 500 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site CP478_RS04620 c301f6a1724881ea49278258c839baba 504 Pfam PF07731 Multicopper oxidase 394 500 1.0E-26 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CP478_RS04620 c301f6a1724881ea49278258c839baba 504 SUPERFAMILY SSF49503 184 362 3.9E-32 T 28-03-2018 IPR008972 Cupredoxin CP478_RS04620 c301f6a1724881ea49278258c839baba 504 ProSitePatterns PS00080 Multicopper oxidases signature 2. 485 496 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Gene3D G3DSA:3.40.50.300 47 238 4.2E-36 T 28-03-2018 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Pfam PF00009 Elongation factor Tu GTP binding domain 51 228 1.5E-51 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 SUPERFAMILY SSF54980 448 543 2.49E-22 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 TIGRFAM TIGR01393 lepA: elongation factor 4 51 645 4.9E-295 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 SUPERFAMILY SSF50447 212 325 4.54E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 90 105 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Gene3D G3DSA:3.30.70.870 336 417 2.5E-27 T 28-03-2018 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Gene3D G3DSA:2.40.30.10 239 335 1.8E-19 T 28-03-2018 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 SUPERFAMILY SSF54980 341 420 4.32E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Pfam PF06421 GTP-binding protein LepA C-terminus 538 642 1.2E-48 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Gene3D G3DSA:3.30.70.240 442 598 8.9E-26 T 28-03-2018 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 PRINTS PR00315 GTP-binding elongation factor signature 54 67 4.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 PRINTS PR00315 GTP-binding elongation factor signature 173 182 4.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 PRINTS PR00315 GTP-binding elongation factor signature 97 105 4.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 PRINTS PR00315 GTP-binding elongation factor signature 121 131 4.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 PRINTS PR00315 GTP-binding elongation factor signature 137 148 4.5E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Hamap MF_00071 Elongation factor 4 [lepA]. 45 650 280.927 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 Pfam PF00679 Elongation factor G C-terminus 448 534 4.7E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 SMART SM00838 447 531 0.0016 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 53 223 4.4E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS13120 af15fe190011bcc3bcb0f55fc82c7520 653 SUPERFAMILY SSF52540 45 249 1.09E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SMART SM00220 11 274 7.0E-68 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Pfam PF03793 PASTA domain 428 488 6.6E-9 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Pfam PF03793 PASTA domain 360 422 3.9E-17 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Pfam PF03793 PASTA domain 562 624 2.8E-9 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Pfam PF03793 PASTA domain 497 557 1.6E-12 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Gene3D G3DSA:3.30.200.20 1 99 1.4E-20 T 28-03-2018 CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Pfam PF00069 Protein kinase domain 11 265 2.0E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SUPERFAMILY SSF56112 8 275 7.69E-77 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SMART SM00740 491 557 1.6E-13 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SMART SM00740 356 422 5.4E-18 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SMART SM00740 423 490 2.7E-12 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 SMART SM00740 558 626 4.4E-9 T 28-03-2018 IPR005543 PASTA domain CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 Gene3D G3DSA:1.10.510.10 100 299 2.7E-53 T 28-03-2018 CP478_RS00085 234d021001b8b0cf9fcbf16338163317 626 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Gene3D G3DSA:1.10.8.10 137 196 1.2E-15 T 28-03-2018 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Pfam PF07499 RuvA, C-terminal domain 151 192 2.3E-10 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Pfam PF14520 Helix-hairpin-helix domain 71 129 5.8E-15 T 28-03-2018 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 SUPERFAMILY SSF47781 66 131 3.15E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Gene3D G3DSA:1.10.150.20 66 136 2.5E-12 T 28-03-2018 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 SUPERFAMILY SSF46929 147 194 1.96E-8 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 190 4.0E-39 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Pfam PF01330 RuvA N terminal domain 1 61 3.8E-20 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 SMART SM00278 72 91 93.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 SMART SM00278 107 126 4.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Gene3D G3DSA:2.40.50.140 1 62 2.7E-25 T 28-03-2018 CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 SUPERFAMILY SSF50249 1 62 1.94E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS14210 8c6e3a8728b0e06c5a5637642ee4258f 196 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 193 29.026 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CP478_RS08905 589a8bbf6fcabf7601fac61a72724a5d 163 Gene3D G3DSA:2.40.50.140 61 126 3.6E-9 T 28-03-2018 CP478_RS08905 589a8bbf6fcabf7601fac61a72724a5d 163 SUPERFAMILY SSF50249 19 128 6.34E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS08905 589a8bbf6fcabf7601fac61a72724a5d 163 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 56 3.5E-10 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CP478_RS08905 589a8bbf6fcabf7601fac61a72724a5d 163 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 59 125 2.4E-12 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 8.0E-269 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 SMART SM00382 346 516 1.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 SMART SM00382 30 233 5.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 SUPERFAMILY SSF52540 8 241 4.0E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 Pfam PF12848 ABC transporter 227 306 5.4E-14 T 28-03-2018 IPR032781 ABC-transporter extension domain CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 SUPERFAMILY SSF52540 314 507 3.82E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 Pfam PF00005 ABC transporter 338 471 1.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 Pfam PF00005 ABC transporter 21 188 4.2E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 Gene3D G3DSA:3.40.50.300 286 538 2.6E-49 T 28-03-2018 CP478_RS13540 3d5a06d3eb490c0beff45691f574ef3c 558 Gene3D G3DSA:3.40.50.300 6 285 2.2E-55 T 28-03-2018 CP478_RS18045 ba9054af311d5f19b1d94b61041c15dc 494 Gene3D G3DSA:3.40.309.10 270 463 3.3E-56 T 28-03-2018 CP478_RS18045 ba9054af311d5f19b1d94b61041c15dc 494 SUPERFAMILY SSF53720 18 482 8.25E-135 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS18045 ba9054af311d5f19b1d94b61041c15dc 494 Gene3D G3DSA:3.40.605.10 14 269 5.3E-74 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS18045 ba9054af311d5f19b1d94b61041c15dc 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS18045 ba9054af311d5f19b1d94b61041c15dc 494 Pfam PF00171 Aldehyde dehydrogenase family 22 474 4.5E-134 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS11535 cf1d44e30d3ef476bd20373c3adf7c32 160 Pfam PF05433 Glycine zipper 2TM domain 86 123 1.0E-5 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 11 343 3.1E-123 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 Gene3D G3DSA:1.10.1610.10 3 68 4.1E-31 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 Gene3D G3DSA:3.40.50.10210 69 326 7.6E-99 T 28-03-2018 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 Pfam PF02277 Phosphoribosyltransferase 8 343 2.2E-129 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 9 345 36.604 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS11995 39cbbcddf15702837699a455fff0dddf 361 SUPERFAMILY SSF52733 6 344 1.96E-111 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 84 105 - T 28-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 Gene3D G3DSA:1.10.645.10 333 482 8.5E-21 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 256 411 4.2E-18 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 Gene3D G3DSA:1.10.645.10 141 332 1.4E-41 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 Pfam PF00374 Nickel-dependent hydrogenase 181 247 4.7E-8 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 16 120 1.6E-16 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 SUPERFAMILY SSF143243 8 157 2.35E-31 T 28-03-2018 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 SUPERFAMILY SSF56762 153 491 2.35E-80 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00485 be260338c22a4b99b096d7636fcc1f53 492 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 66 119 1.0E-25 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS19040 faa4308440585b7eebd12a419a62bf4d 229 Pfam PF11139 Sap, sulfolipid-1-addressing protein 18 227 2.9E-60 T 28-03-2018 IPR021315 Glycolipid exporter Gap/Sap CP478_RS00135 50a04637cdabe147d081f168e600848e 256 Gene3D G3DSA:1.10.260.40 2 80 5.7E-13 T 28-03-2018 CP478_RS00135 50a04637cdabe147d081f168e600848e 256 SUPERFAMILY SSF47413 6 62 6.97E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS00135 50a04637cdabe147d081f168e600848e 256 SMART SM00530 9 64 1.3E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS00135 50a04637cdabe147d081f168e600848e 256 Pfam PF01381 Helix-turn-helix 10 61 1.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 Gene3D G3DSA:3.10.310.10 142 269 1.9E-36 T 28-03-2018 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 Gene3D G3DSA:3.10.310.10 1 141 1.9E-41 T 28-03-2018 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 SUPERFAMILY SSF54506 149 279 1.03E-26 T 28-03-2018 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 282 28.605 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 SUPERFAMILY SSF54506 1 139 3.66E-29 T 28-03-2018 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 Pfam PF01678 Diaminopimelate epimerase 3 141 1.6E-42 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 Pfam PF01678 Diaminopimelate epimerase 158 272 1.0E-19 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CP478_RS14935 3794f42db41f9ccdf6c9aec233076500 289 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 281 1.2E-83 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CP478_RS18190 17803adfa6bb48655e9ad8363c18df9d 142 Gene3D G3DSA:3.40.50.1010 1 141 2.6E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18190 17803adfa6bb48655e9ad8363c18df9d 142 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 141 4.7E-46 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS18190 17803adfa6bb48655e9ad8363c18df9d 142 SUPERFAMILY SSF88723 1 131 1.12E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18190 17803adfa6bb48655e9ad8363c18df9d 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 137 14.604 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS18190 17803adfa6bb48655e9ad8363c18df9d 142 Pfam PF01850 PIN domain 4 127 6.9E-10 T 28-03-2018 IPR002716 PIN domain CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Pfam PF04545 Sigma-70, region 4 209 258 3.2E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 SUPERFAMILY SSF88946 17 112 7.22E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Pfam PF04542 Sigma-70 region 2 44 112 2.5E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Gene3D G3DSA:1.10.10.10 199 259 3.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 PRINTS PR00046 Major sigma-70 factor signature 230 245 9.8E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 PRINTS PR00046 Major sigma-70 factor signature 67 80 9.8E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 PRINTS PR00046 Major sigma-70 factor signature 245 256 9.8E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 PRINTS PR00046 Major sigma-70 factor signature 213 225 9.8E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 SUPERFAMILY SSF88659 116 192 2.31E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 260 2.5E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 38 260 1.2E-90 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 SUPERFAMILY SSF88659 176 260 6.17E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Gene3D G3DSA:1.10.10.10 113 165 3.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Pfam PF04539 Sigma-70 region 3 126 186 5.1E-11 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18010 9e6a20e90632ae6f34f16f2d4e53f384 261 Gene3D G3DSA:1.10.601.10 19 111 1.3E-16 T 28-03-2018 CP478_RS13090 a799527df51487d5a82d20b5df4e73e9 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 274 6.2E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS13090 a799527df51487d5a82d20b5df4e73e9 283 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 28 273 1.6E-74 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CP478_RS13090 a799527df51487d5a82d20b5df4e73e9 283 Gene3D G3DSA:1.10.3720.10 27 281 2.4E-41 T 28-03-2018 CP478_RS13090 a799527df51487d5a82d20b5df4e73e9 283 SUPERFAMILY SSF161098 29 269 1.31E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS13090 a799527df51487d5a82d20b5df4e73e9 283 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 28 276 1.6E-81 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SMART SM01009 201 316 1.4E-46 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:1.10.10.60 138 198 1.5E-7 T 28-03-2018 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:1.10.1670.10 449 487 1.8E-13 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SUPERFAMILY SSF48150 306 480 8.72E-40 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SUPERFAMILY SSF55945 202 297 1.88E-23 T 28-03-2018 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Pfam PF02805 Metal binding domain of Ada 8 71 8.4E-28 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SMART SM00478 326 483 4.0E-32 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SUPERFAMILY SSF57884 3 85 1.15E-30 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Pfam PF06029 AlkA N-terminal domain 202 316 7.1E-29 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:1.10.340.30 303 448 6.5E-26 T 28-03-2018 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SMART SM00342 100 183 2.6E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 SUPERFAMILY SSF46689 137 185 3.99E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:3.30.310.20 201 302 1.0E-32 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:1.10.10.60 80 137 3.0E-5 T 28-03-2018 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 322 470 9.1E-7 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Pfam PF12833 Helix-turn-helix domain 106 185 2.1E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS07225 c0f4074638d82addf5e5a3b3937745ba 496 Gene3D G3DSA:3.40.10.10 2 73 2.1E-22 T 28-03-2018 IPR035451 Ada-like domain CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 35 148 5.1E-44 T 28-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 PIRSF PIRSF026640 7 196 3.6E-75 T 28-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 Gene3D G3DSA:1.20.59.10 40 122 5.6E-16 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 SMART SM00830 32 112 2.5E-15 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 Pfam PF01817 Chorismate mutase type II 41 110 4.2E-10 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS10250 2e6e5d0bc94acc159a505d391a0c3c10 199 SUPERFAMILY SSF48600 39 194 2.08E-43 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 9.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 9.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 9.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 9.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 9.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 3.1E-107 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 32 215 8.8E-63 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 513 1.5E-207 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 PIRSF PIRSF000110 5 514 6.9E-179 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 28 513 90.855 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 SUPERFAMILY SSF55347 205 512 2.13E-108 T 28-03-2018 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 Gene3D G3DSA:3.30.360.10 217 514 8.7E-121 T 28-03-2018 CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 SUPERFAMILY SSF51735 17 218 5.31E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS07935 69ba850f68740ec2a4cf5cef8374c243 514 Gene3D G3DSA:3.40.50.720 26 216 2.2E-68 T 28-03-2018 CP478_RS08745 2a5dbd3835f9cefaed12216358a9824c 136 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 126 8.4E-26 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS08745 2a5dbd3835f9cefaed12216358a9824c 136 Gene3D G3DSA:2.30.110.10 13 128 3.9E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS08745 2a5dbd3835f9cefaed12216358a9824c 136 Pfam PF04075 F420H(2)-dependent quinone reductase 23 95 2.3E-5 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS18725 b8f7328ca806918b4bada05599cd97bb 168 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 26 154 3.6E-29 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CP478_RS18725 b8f7328ca806918b4bada05599cd97bb 168 Gene3D G3DSA:3.40.50.300 19 168 6.7E-41 T 28-03-2018 CP478_RS18725 b8f7328ca806918b4bada05599cd97bb 168 SUPERFAMILY SSF52540 40 150 9.85E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18725 b8f7328ca806918b4bada05599cd97bb 168 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 28 155 5.2E-20 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CP478_RS13420 6d43cf74a31fca90af483b5b66e3d119 418 Pfam PF07690 Major Facilitator Superfamily 26 279 3.3E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS13420 6d43cf74a31fca90af483b5b66e3d119 418 Gene3D G3DSA:1.20.1250.20 202 412 7.4E-21 T 28-03-2018 CP478_RS13420 6d43cf74a31fca90af483b5b66e3d119 418 Gene3D G3DSA:1.20.1250.20 11 201 2.5E-19 T 28-03-2018 CP478_RS13420 6d43cf74a31fca90af483b5b66e3d119 418 SUPERFAMILY SSF103473 11 403 6.67E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 Pfam PF00557 Metallopeptidase family M24 23 257 5.3E-40 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 Gene3D G3DSA:3.90.230.10 11 265 1.3E-65 T 28-03-2018 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 SUPERFAMILY SSF55920 16 264 1.19E-72 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 264 4.1E-78 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 91 2.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 101 117 2.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 220 2.4E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS03970 80ad0be70c179751a445e40a85579cb9 266 Hamap MF_01974 Methionine aminopeptidase [map]. 13 266 37.078 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 28-03-2018 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 3.9E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Gene3D G3DSA:1.10.8.60 317 408 1.4E-34 T 28-03-2018 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 9.5E-196 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 SMART SM00382 113 266 1.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 SMART SM00994 10 49 1.1E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 SUPERFAMILY SSF52540 59 404 8.91E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Gene3D G3DSA:3.40.50.300 53 315 4.4E-67 T 28-03-2018 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.803 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 SMART SM01086 317 407 3.7E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS13425 502263013cdd8cbf917722f54464c2bb 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 6.2E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CP478_RS02865 1aca0b2e9a7e22f492a21581224afc92 292 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 285 2.6E-130 T 28-03-2018 CP478_RS02865 1aca0b2e9a7e22f492a21581224afc92 292 PIRSF PIRSF005355 1 291 5.5E-83 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CP478_RS02865 1aca0b2e9a7e22f492a21581224afc92 292 Pfam PF01040 UbiA prenyltransferase family 20 250 2.4E-29 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CP478_RS02865 1aca0b2e9a7e22f492a21581224afc92 292 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 286 20.411 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CP478_RS09415 7ac32719e1128b29afed1de37277b230 461 Pfam PF08031 Berberine and berberine like 413 458 5.9E-13 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CP478_RS09415 7ac32719e1128b29afed1de37277b230 461 Gene3D G3DSA:3.30.43.10 17 93 2.2E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS09415 7ac32719e1128b29afed1de37277b230 461 Gene3D G3DSA:3.30.465.10 94 232 1.8E-34 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS09415 7ac32719e1128b29afed1de37277b230 461 SUPERFAMILY SSF56176 16 207 2.38E-48 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS09415 7ac32719e1128b29afed1de37277b230 461 Pfam PF01565 FAD binding domain 42 175 2.0E-28 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 PRINTS PR00502 NUDIX hydrolase family signature 112 127 1.4E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 PRINTS PR00502 NUDIX hydrolase family signature 98 112 1.4E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 ProSitePatterns PS00893 Nudix box signature. 103 124 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 Gene3D G3DSA:3.90.79.10 62 205 6.8E-28 T 28-03-2018 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 Pfam PF00293 NUDIX domain 87 190 9.3E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS21355 58e98c0f1e67e1aff405ff3fd0136550 248 SUPERFAMILY SSF55811 86 196 2.71E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 287 9.1E-36 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 SUPERFAMILY SSF48179 161 289 2.95E-37 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 Gene3D G3DSA:1.10.1040.10 171 293 1.4E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 SUPERFAMILY SSF51735 3 160 1.36E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 159 2.5E-46 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 Gene3D G3DSA:3.40.50.720 2 170 1.8E-31 T 28-03-2018 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 PIRSF PIRSF000103 1 294 6.4E-88 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CP478_RS04085 c282bebeaaaf174a9ee24f34b78f7e0c 294 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 289 9.4E-109 T 28-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CP478_RS10330 a88bf96667c42b0e7e573c5f3571ab0f 143 SUPERFAMILY SSF69500 1 142 1.01E-44 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CP478_RS10330 a88bf96667c42b0e7e573c5f3571ab0f 143 Gene3D G3DSA:3.50.80.10 1 143 1.5E-48 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CP478_RS10330 a88bf96667c42b0e7e573c5f3571ab0f 143 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 142 1.5E-48 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CP478_RS10330 a88bf96667c42b0e7e573c5f3571ab0f 143 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 143 29.493 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CP478_RS10330 a88bf96667c42b0e7e573c5f3571ab0f 143 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 142 2.2E-38 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CP478_RS13810 e1aea5e6e54d5e4cb0d2fe54d4321581 157 SUPERFAMILY SSF52833 5 155 2.21E-50 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS13810 e1aea5e6e54d5e4cb0d2fe54d4321581 157 Pfam PF00578 AhpC/TSA family 10 136 6.6E-41 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS13810 e1aea5e6e54d5e4cb0d2fe54d4321581 157 PIRSF PIRSF000239 2 155 3.0E-20 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS13810 e1aea5e6e54d5e4cb0d2fe54d4321581 157 Gene3D G3DSA:3.40.30.10 1 156 3.3E-45 T 28-03-2018 CP478_RS20485 27f11578401dc4083c0d378d5b5e24d3 75 Gene3D G3DSA:1.10.443.10 1 74 6.6E-17 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS20485 27f11578401dc4083c0d378d5b5e24d3 75 Pfam PF00589 Phage integrase family 4 57 2.6E-11 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS20485 27f11578401dc4083c0d378d5b5e24d3 75 SUPERFAMILY SSF56349 4 63 8.54E-18 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 SUPERFAMILY SSF140459 2 171 3.66E-58 T 28-03-2018 CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Gene3D G3DSA:1.10.287.1060 22 111 4.9E-6 T 28-03-2018 CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF00823 PPE family 5 162 3.0E-57 T 28-03-2018 IPR000030 PPE family CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 422 459 1.8E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 432 469 2.7E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 412 449 2.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 451 489 1.1E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 335 371 8.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19315 4bd00b53a7c2edf4d19a9145d5ac95dd 582 Pfam PF01469 Pentapeptide repeats (8 copies) 392 429 3.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 Pfam PF02310 B12 binding domain 618 731 1.3E-14 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 SUPERFAMILY SSF51703 37 578 7.85E-212 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 SUPERFAMILY SSF52242 582 746 6.41E-58 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 615 744 5.9E-63 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 397 422 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 50 583 1.7E-286 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 Gene3D G3DSA:3.40.50.280 599 746 7.7E-38 T 28-03-2018 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 Pfam PF01642 Methylmalonyl-CoA mutase 52 576 7.4E-229 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08185 ad8e19acc4b84dfcb5670f03f360eb5c 750 Gene3D G3DSA:3.20.20.240 50 578 1.9E-236 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS18650 6eeb8e5de1554fd7ee41097ee811bba4 99 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 10 52 1.8E-8 T 28-03-2018 CP478_RS18650 6eeb8e5de1554fd7ee41097ee811bba4 99 Gene3D G3DSA:3.40.1620.10 9 73 1.3E-14 T 28-03-2018 CP478_RS18650 6eeb8e5de1554fd7ee41097ee811bba4 99 SUPERFAMILY SSF143120 10 56 6.67E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS18650 6eeb8e5de1554fd7ee41097ee811bba4 99 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 10 69 2.8E-10 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 7.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 Gene3D G3DSA:1.10.260.40 48 69 0.002 T 28-03-2018 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 Gene3D G3DSA:1.10.357.10 70 197 1.2E-7 T 28-03-2018 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 Gene3D G3DSA:1.10.10.60 7 47 3.0E-17 T 28-03-2018 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 SUPERFAMILY SSF46689 9 91 2.05E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06870 534a60e022924566d1ecad1180edc86b 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 SUPERFAMILY SSF46689 13 90 5.13E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 Gene3D G3DSA:1.10.357.10 68 213 9.4E-21 T 28-03-2018 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 Gene3D G3DSA:1.10.10.60 1 67 2.4E-20 T 28-03-2018 CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 SUPERFAMILY SSF48498 98 210 3.51E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS08410 7fe7a136f513e860b6c02bd9802b08e5 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.7E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Gene3D G3DSA:1.20.140.10 218 380 1.4E-43 T 28-03-2018 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 SUPERFAMILY SSF47203 228 378 5.96E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 3.0E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 1.4E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 2.1E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Gene3D G3DSA:2.40.110.10 122 217 7.7E-36 T 28-03-2018 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 SUPERFAMILY SSF56645 2 236 7.07E-73 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS05320 6495be6ad5186bc37248ca209aa41e3d 382 Gene3D G3DSA:1.10.540.10 3 121 8.7E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 Gene3D G3DSA:3.50.50.60 138 249 6.2E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 16 315 2.6E-125 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 Gene3D G3DSA:3.50.50.60 250 330 8.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 145 165 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 5.3E-37 T 28-03-2018 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 5.3E-37 T 28-03-2018 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 5.3E-37 T 28-03-2018 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 5.3E-37 T 28-03-2018 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 5.3E-37 T 28-03-2018 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 Gene3D G3DSA:3.50.50.60 8 137 1.7E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 SUPERFAMILY SSF51905 10 315 1.51E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 49 64 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 153 177 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 70 80 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 205 221 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 150 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 264 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 16 38 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 1.2E-79 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CP478_RS21380 7cce8cd101ef0f59d60b69620135b2a2 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 304 4.2E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 Pfam PF13353 4Fe-4S single cluster domain 99 183 4.2E-7 T 28-03-2018 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 Pfam PF04055 Radical SAM superfamily 98 258 5.1E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 Pfam PF13649 Methyltransferase domain 565 660 2.1E-18 T 28-03-2018 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 SUPERFAMILY SSF102114 79 333 9.61E-37 T 28-03-2018 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 Gene3D G3DSA:3.40.50.150 536 776 2.9E-36 T 28-03-2018 CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 SUPERFAMILY SSF53335 526 776 1.3E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20375 aabfedda821e0b73ed5dd3ee3f7588dd 776 Gene3D G3DSA:3.20.20.70 78 469 7.3E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS00480 f2cf33c26221e4a2ed7e2a2e7954048a 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 313 325 3.4E-7 T 28-03-2018 CP478_RS00480 f2cf33c26221e4a2ed7e2a2e7954048a 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 65 90 3.4E-7 T 28-03-2018 CP478_RS00480 f2cf33c26221e4a2ed7e2a2e7954048a 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 3.4E-7 T 28-03-2018 CP478_RS00480 f2cf33c26221e4a2ed7e2a2e7954048a 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 3.4E-7 T 28-03-2018 CP478_RS00480 f2cf33c26221e4a2ed7e2a2e7954048a 488 Pfam PF00361 Proton-conducting membrane transporter 124 419 3.1E-45 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 406 419 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 140 155 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 115 123 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 89 102 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 350 361 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 202 215 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 126 139 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 216 229 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 PRINTS PR00415 Aconitase family signature 293 307 1.8E-48 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 7 473 59.385 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 Pfam PF00330 Aconitase family (aconitate hydratase) 13 464 1.6E-155 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 8 466 6.5E-219 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 Gene3D G3DSA:3.40.1060.10 161 295 2.9E-42 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 Gene3D G3DSA:3.30.499.10 332 473 3.2E-51 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 SUPERFAMILY SSF53732 7 471 2.09E-158 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 Gene3D G3DSA:3.30.499.10 1 160 5.6E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 ProSitePatterns PS00450 Aconitase family signature 1. 346 362 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CP478_RS16335 57234ed4d73e01cc348bed7dc9e8975f 473 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 Pfam PF02609 Exonuclease VII small subunit 24 73 1.3E-15 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 23 83 13.329 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 SUPERFAMILY SSF116842 18 81 8.76E-16 T 28-03-2018 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 24 64 3.0E-16 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 Gene3D G3DSA:1.10.287.1040 21 84 3.1E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 PIRSF PIRSF006488 13 85 1.0E-27 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06070 fd1fe7096cb1f1b98f16e6cccf6169fc 85 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 24 78 8.5E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 181 349 1.7E-29 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 SUPERFAMILY SSF55021 7 86 1.06E-10 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Gene3D G3DSA:3.40.50.1000 239 384 3.2E-29 T 28-03-2018 IPR023214 HAD-like domain CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Gene3D G3DSA:3.30.70.260 94 177 1.4E-16 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Gene3D G3DSA:3.30.70.260 6 87 4.7E-15 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Pfam PF12710 haloacid dehalogenase-like hydrolase 182 349 8.3E-29 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Pfam PF13740 ACT domain 7 79 5.2E-19 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 Gene3D G3DSA:1.10.150.210 192 238 4.7E-22 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 167 384 4.9E-73 T 28-03-2018 CP478_RS16640 1de4ca89146004b10b8972bb2bcec6c6 409 SUPERFAMILY SSF56784 179 386 8.27E-51 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20455 af6b645502cd5f4f4266d9062b6928ac 111 Pfam PF00934 PE family 1 91 1.7E-10 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 ProSitePatterns PS00397 Site-specific recombinases active site. 55 63 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 Gene3D G3DSA:3.40.50.1390 47 192 5.2E-21 T 28-03-2018 CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 SUPERFAMILY SSF53041 51 182 1.31E-18 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 Gene3D G3DSA:1.10.1660.20 1 45 2.2E-7 T 28-03-2018 CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 Pfam PF00239 Resolvase, N terminal domain 53 186 4.9E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS03235 1e41f082f7cfb9a346073fdb7fb01c5b 194 SMART SM00857 52 187 3.3E-11 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 9.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 9.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 9.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 Gene3D G3DSA:1.10.10.10 125 216 7.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 SUPERFAMILY SSF52172 8 134 6.55E-31 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 Gene3D G3DSA:3.40.50.2300 1 124 6.8E-32 T 28-03-2018 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 Pfam PF00072 Response regulator receiver domain 11 122 1.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 SMART SM00448 9 122 1.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 SMART SM00421 152 209 7.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04610 22e2dfd150100014964c5cfb9375b69c 216 SUPERFAMILY SSF46894 145 215 1.09E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 8 257 1.4E-109 T 28-03-2018 IPR017518 Conserved hypothetical protein CHP03084 CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 Pfam PF08608 Wyosine base formation 183 226 3.2E-9 T 28-03-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 1.1E-30 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 SUPERFAMILY SSF109854 1 152 5.04E-34 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 Gene3D G3DSA:1.20.120.450 2 153 2.2E-23 T 28-03-2018 CP478_RS00205 db392d22b8c76b01f6c8aaf80c6e9232 257 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 7.9E-48 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 SMART SM00363 357 418 1.8E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 8.2E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 8.2E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 8.2E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 8.2E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 Pfam PF00579 tRNA synthetases class I (W and Y) 30 325 1.1E-81 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 422 42.836 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 Gene3D G3DSA:1.10.240.10 225 326 1.5E-29 T 28-03-2018 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 Gene3D G3DSA:3.40.50.620 6 224 6.6E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 SUPERFAMILY SSF55174 328 420 4.12E-16 T 28-03-2018 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 419 9.2E-110 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 Gene3D G3DSA:3.10.290.10 327 423 1.4E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09220 60a87b8eb6c659deb57ccf9a1c01a01c 424 SUPERFAMILY SSF52374 5 325 3.19E-92 T 28-03-2018 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 Pfam PF04055 Radical SAM superfamily 176 348 9.6E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 Gene3D G3DSA:3.40.50.280 1 116 3.5E-6 T 28-03-2018 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 SMART SM00729 170 394 5.7E-26 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 Gene3D G3DSA:3.20.20.70 117 431 1.9E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 SUPERFAMILY SSF102114 146 378 2.88E-28 T 28-03-2018 CP478_RS01155 3dda9b51c4c08a0fdb2a9703fb07d0bd 443 Pfam PF02310 B12 binding domain 3 116 1.4E-12 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS11815 3918c849d5e623e7dc2a7ca41f78b29e 352 SUPERFAMILY SSF48576 7 351 1.49E-66 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS11815 3918c849d5e623e7dc2a7ca41f78b29e 352 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS11815 3918c849d5e623e7dc2a7ca41f78b29e 352 Pfam PF00348 Polyprenyl synthetase 36 290 1.2E-46 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CP478_RS11815 3918c849d5e623e7dc2a7ca41f78b29e 352 Gene3D G3DSA:1.10.600.10 3 352 3.1E-77 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS11815 3918c849d5e623e7dc2a7ca41f78b29e 352 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 228 240 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS19485 79ffeda80b572811ee3312131e6557e4 283 Gene3D G3DSA:3.30.2140.10 154 273 2.9E-15 T 28-03-2018 CP478_RS19485 79ffeda80b572811ee3312131e6557e4 283 Pfam PF00797 N-acetyltransferase 21 258 5.6E-80 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CP478_RS19485 79ffeda80b572811ee3312131e6557e4 283 SUPERFAMILY SSF54001 2 260 7.06E-83 T 28-03-2018 CP478_RS19485 79ffeda80b572811ee3312131e6557e4 283 Gene3D G3DSA:3.30.2140.10 2 152 4.0E-37 T 28-03-2018 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Pfam PF00501 AMP-binding enzyme 48 439 3.0E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Gene3D G3DSA:3.30.300.30 433 535 4.9E-31 T 28-03-2018 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Gene3D G3DSA:2.30.38.10 353 432 3.2E-17 T 28-03-2018 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Gene3D G3DSA:3.40.50.980 41 202 2.1E-30 T 28-03-2018 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 SUPERFAMILY SSF56801 45 532 2.75E-125 T 28-03-2018 CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 523 1.8E-23 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS07805 d5aba73b9f48592720c0396ac01d2f00 535 Gene3D G3DSA:3.40.50.980 203 352 1.8E-32 T 28-03-2018 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 PIRSF PIRSF000386 1 230 5.8E-87 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 Gene3D G3DSA:3.40.1280.10 1 170 3.1E-67 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 224 5.6E-70 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 Gene3D G3DSA:1.10.1270.20 171 229 1.9E-27 T 28-03-2018 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 230 94.355 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 226 5.7E-69 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CP478_RS15875 e1fa8a034937fb31276f368055a73f9f 230 SUPERFAMILY SSF75217 2 227 3.92E-83 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 402 411 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 409 432 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 263 280 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 365 389 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 399 409 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 283 309 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00463 E-class P450 group I signature 127 145 2.0E-23 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 Gene3D G3DSA:1.10.630.10 2 460 5.8E-101 T 28-03-2018 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 Pfam PF00067 Cytochrome P450 45 444 6.3E-66 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 SUPERFAMILY SSF48264 43 461 2.62E-93 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00385 P450 superfamily signature 326 337 6.8E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00385 P450 superfamily signature 274 291 6.8E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00385 P450 superfamily signature 400 409 6.8E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS07640 f68e60387f03aa6e771cdf341f5ce471 461 PRINTS PR00385 P450 superfamily signature 409 420 6.8E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 SUPERFAMILY SSF52540 521 750 1.42E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 SMART SM00487 529 722 2.1E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 Pfam PF00176 SNF2 family N-terminal domain 550 819 2.3E-58 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 Pfam PF00271 Helicase conserved C-terminal domain 841 950 1.8E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 Gene3D G3DSA:3.40.50.300 823 988 6.4E-34 T 28-03-2018 CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 Gene3D G3DSA:3.40.50.10810 515 756 8.8E-52 T 28-03-2018 CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 Pfam PF12419 SNF2 Helicase protein 352 486 8.6E-41 T 28-03-2018 IPR022138 Helicase SWF/SNF-related CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 SUPERFAMILY SSF52540 754 1006 5.9E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11435 1c5271de8c42a4c3c91a25b02dd9d0a5 1013 SMART SM00490 867 950 8.0E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 Gene3D G3DSA:2.60.40.1180 274 312 1.7E-9 T 28-03-2018 CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 228 268 3.0E-10 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 272 311 1.0E-9 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 Gene3D G3DSA:2.130.10.10 167 273 9.1E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 SUPERFAMILY SSF63825 207 330 6.41E-23 T 28-03-2018 CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 Pfam PF01436 NHL repeat 217 243 8.5E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 Pfam PF00934 PE family 1 92 4.2E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05340 47d13eb16d85494183ab237f8f234849 331 SUPERFAMILY SSF140459 8 82 1.94E-20 T 28-03-2018 CP478_RS06325 4bab6e662fd04a2d0ebe6457bd26db04 282 Gene3D G3DSA:3.40.50.150 2 194 1.5E-31 T 28-03-2018 CP478_RS06325 4bab6e662fd04a2d0ebe6457bd26db04 282 PIRSF PIRSF028177 5 278 2.9E-81 T 28-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CP478_RS06325 4bab6e662fd04a2d0ebe6457bd26db04 282 Pfam PF04072 Leucine carboxyl methyltransferase 20 179 2.4E-12 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS06325 4bab6e662fd04a2d0ebe6457bd26db04 282 SUPERFAMILY SSF53335 16 244 9.97E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 Gene3D G3DSA:1.10.1060.10 135 263 8.5E-27 T 28-03-2018 CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 SUPERFAMILY SSF46548 135 260 2.09E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 28 256 3.5E-73 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 25 139 1.4E-29 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 SUPERFAMILY SSF54292 23 134 1.05E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 Pfam PF13183 4Fe-4S dicluster domain 174 246 6.0E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 Gene3D G3DSA:3.10.20.30 18 134 9.1E-30 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS18185 c03e9a2205a62db3e62e54d4bdf6130d 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 176 187 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS12500 7e0198997cd153f1367cdd9d92817f87 230 SMART SM01110 43 229 6.5E-92 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS12500 7e0198997cd153f1367cdd9d92817f87 230 Gene3D G3DSA:3.40.50.1820 35 230 4.0E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12500 7e0198997cd153f1367cdd9d92817f87 230 SUPERFAMILY SSF53474 36 229 2.03E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12500 7e0198997cd153f1367cdd9d92817f87 230 Pfam PF01083 Cutinase 44 229 6.4E-53 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS12500 7e0198997cd153f1367cdd9d92817f87 230 ProSitePatterns PS00155 Cutinase, serine active site. 113 125 - T 28-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CP478_RS00500 c47f78a3e1c33c5565786aec12aea297 256 Pfam PF09900 Predicted membrane protein (DUF2127) 83 224 1.6E-34 T 28-03-2018 IPR021125 Protein of unknown function DUF2127 CP478_RS00500 c47f78a3e1c33c5565786aec12aea297 256 PIRSF PIRSF021485 1 256 1.4E-145 T 28-03-2018 IPR014511 Protein of unknown function DUF2068, transmembrane, subgroup CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 17 296 2.9E-83 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 180 198 4.4E-14 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 33 53 4.4E-14 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 96 112 4.4E-14 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 300 319 4.4E-14 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 Gene3D G3DSA:1.20.120.570 137 302 5.4E-5 T 28-03-2018 CP478_RS19125 a22295bc2b5b734d104e48a5be7ce7c2 357 Pfam PF02470 MlaD protein 44 118 1.7E-16 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 Pfam PF13622 Thioesterase-like superfamily 31 288 1.5E-36 T 28-03-2018 CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 Gene3D G3DSA:3.10.129.10 2 122 1.4E-22 T 28-03-2018 CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 SMART SM00046 72 200 5.8E-28 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 SUPERFAMILY SSF54637 22 117 1.66E-10 T 28-03-2018 IPR029069 HotDog domain CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 Gene3D G3DSA:3.10.129.10 184 291 0.027 T 28-03-2018 CP478_RS02665 dc6f8f4c5b0fdd1ecf9aa8ce44d23c35 291 SUPERFAMILY SSF54637 169 288 8.72E-7 T 28-03-2018 IPR029069 HotDog domain CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 3.4E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Gene3D G3DSA:2.40.110.10 119 221 2.5E-35 T 28-03-2018 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Gene3D G3DSA:1.20.140.10 222 390 1.1E-53 T 28-03-2018 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 SUPERFAMILY SSF47203 231 384 6.77E-53 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.5E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 PIRSF PIRSF016578 3 380 6.7E-14 T 28-03-2018 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 114 8.6E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 Gene3D G3DSA:1.10.540.10 1 116 1.8E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS04090 74756a502a284bfa7bb9f67cbe8fc486 390 SUPERFAMILY SSF56645 2 246 1.7E-72 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS20290 1b1e9d0621edc7e8b07a9d25fe008f05 296 Gene3D G3DSA:3.40.960.10 192 295 3.2E-11 T 28-03-2018 CP478_RS20290 1b1e9d0621edc7e8b07a9d25fe008f05 296 SUPERFAMILY SSF52980 190 289 2.2E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS15200 bd379fb4f6e68cc525ca2d258041fac4 153 Pfam PF00583 Acetyltransferase (GNAT) family 40 122 1.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS15200 bd379fb4f6e68cc525ca2d258041fac4 153 SUPERFAMILY SSF55729 25 149 2.4E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS15200 bd379fb4f6e68cc525ca2d258041fac4 153 Gene3D G3DSA:3.40.630.30 2 152 2.5E-19 T 28-03-2018 CP478_RS07340 f856e77067ec55034c52107ee966acc6 273 Gene3D G3DSA:3.60.15.10 18 272 3.1E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS07340 f856e77067ec55034c52107ee966acc6 273 SUPERFAMILY SSF56281 19 269 7.99E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS07340 f856e77067ec55034c52107ee966acc6 273 Pfam PF12706 Beta-lactamase superfamily domain 65 237 8.6E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS12665 e3ba34151d469104910a527e0d90ceb8 302 Gene3D G3DSA:3.75.10.10 39 300 5.2E-57 T 28-03-2018 CP478_RS12665 e3ba34151d469104910a527e0d90ceb8 302 SUPERFAMILY SSF55909 40 300 4.1E-57 T 28-03-2018 CP478_RS12665 e3ba34151d469104910a527e0d90ceb8 302 Pfam PF02274 Amidinotransferase 96 301 2.1E-17 T 28-03-2018 CP478_RS11625 beaa4a44499a68eb21675d79564c905b 358 SUPERFAMILY SSF63829 117 354 1.31E-18 T 28-03-2018 CP478_RS11625 beaa4a44499a68eb21675d79564c905b 358 Gene3D G3DSA:2.130.10.10 255 357 2.7E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS11625 beaa4a44499a68eb21675d79564c905b 358 Gene3D G3DSA:2.130.10.10 69 254 2.9E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 Gene3D G3DSA:3.30.420.10 181 341 3.8E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 SUPERFAMILY SSF46689 5 105 2.78E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 Pfam PF00665 Integrase core domain 186 291 5.5E-9 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 Gene3D G3DSA:1.10.260.40 38 107 2.5E-4 T 28-03-2018 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 Pfam PF13936 Helix-turn-helix domain 6 48 6.4E-17 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 Gene3D G3DSA:1.10.10.60 6 37 7.0E-16 T 28-03-2018 CP478_RS17465 865d1093b4adebb3bc1466306dea0895 344 SUPERFAMILY SSF53098 186 332 2.47E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 Pfam PF00117 Glutamine amidotransferase class-I 8 199 2.2E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 PIRSF PIRSF000495 4 206 7.1E-62 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 204 1.9E-71 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 Gene3D G3DSA:3.40.50.880 1 206 1.6E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 SUPERFAMILY SSF52317 4 204 5.14E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS08765 09fefeea151626858a489ecaaca99d75 206 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 205 31.152 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 PIRSF PIRSF002741 32 539 1.0E-58 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 462 3.8E-46 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 Gene3D G3DSA:3.40.190.10 172 325 3.9E-24 T 28-03-2018 CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 Gene3D G3DSA:3.10.105.10 326 511 9.0E-36 T 28-03-2018 CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 Gene3D G3DSA:3.90.76.10 49 171 3.9E-19 T 28-03-2018 CP478_RS20015 31a39b8d865c8e79fa159c37b4f48511 541 SUPERFAMILY SSF53850 32 537 6.38E-87 T 28-03-2018 CP478_RS08255 8d6ddad14a9058faca6bf2d783440366 231 Pfam PF08889 WbqC-like protein family 8 223 8.1E-79 T 28-03-2018 IPR014985 WbqC-like protein family CP478_RS20450 99f2112b748ab3d05d6026566e66e89f 70 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 5 64 2.6E-23 T 28-03-2018 IPR018714 Protein of unknown function DUF2237 CP478_RS18695 0e08e021bf6702e92178de4ea2e88a71 102 Pfam PF02467 Transcription factor WhiB 17 85 7.9E-25 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS18695 0e08e021bf6702e92178de4ea2e88a71 102 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.951 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 Pfam PF01979 Amidohydrolase family 65 398 7.1E-52 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 SUPERFAMILY SSF51556 69 361 1.24E-69 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 SUPERFAMILY SSF51338 31 68 4.57E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 SUPERFAMILY SSF51338 361 399 4.57E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 Gene3D G3DSA:3.20.20.140 85 342 8.5E-48 T 28-03-2018 CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 Gene3D G3DSA:2.30.40.10 343 402 7.2E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS00410 611e052a07eda841fe07d051ebf1c198 411 Gene3D G3DSA:2.30.40.10 16 84 8.5E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS18470 883d8bf6c2a61d9f0c704d5d578f9a36 53 Pfam PF00934 PE family 20 49 3.3E-5 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 29 266 4.3E-86 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 SUPERFAMILY SSF53167 12 267 4.87E-79 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 Pfam PF01048 Phosphorylase superfamily 29 266 1.3E-41 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 Gene3D G3DSA:3.40.50.1580 2 268 2.4E-61 T 28-03-2018 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 PIRSF PIRSF000477 2 268 6.5E-109 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 29 266 3.1E-118 T 28-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CP478_RS18115 d38dc383826bdda8c6efad8728bd227d 268 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 83 124 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 SUPERFAMILY SSF51735 7 240 6.93E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 Gene3D G3DSA:3.40.50.720 1 48 3.9E-6 T 28-03-2018 CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 Gene3D G3DSA:3.40.50.720 49 250 4.3E-61 T 28-03-2018 CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 1.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 237 3.6E-63 T 28-03-2018 CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10915 3127e50b46e58a44137bdfe40339386c 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.2E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 Gene3D G3DSA:3.30.565.10 227 389 2.1E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 222 7.8E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 333 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 319 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 SUPERFAMILY SSF55874 213 379 3.93E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 SUPERFAMILY SSF47384 141 221 2.35E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 SMART SM00388 157 223 3.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 SMART SM00387 268 380 4.3E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 378 7.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 Gene3D G3DSA:3.30.450.20 48 162 1.4E-5 T 28-03-2018 CP478_RS02610 fe9bb432e648eed824f4b5cb5221bc66 410 Gene3D G3DSA:1.10.287.130 163 219 1.5E-12 T 28-03-2018 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 Pfam PF00067 Cytochrome P450 41 416 2.1E-61 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 Gene3D G3DSA:1.10.630.10 29 441 6.5E-87 T 28-03-2018 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 381 390 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 SUPERFAMILY SSF48264 16 441 7.99E-84 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 255 272 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 305 323 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 378 388 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 43 62 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 275 301 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 346 370 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00463 E-class P450 group I signature 388 411 4.3E-26 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00385 P450 superfamily signature 306 317 7.5E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00385 P450 superfamily signature 388 399 7.5E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00385 P450 superfamily signature 379 388 7.5E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00740 1cd495d77f7a7275a9f06caf9234ff8f 441 PRINTS PR00385 P450 superfamily signature 266 283 7.5E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS05740 50d94e80583b20c1fe0ff2d55a562280 371 Gene3D G3DSA:1.10.10.10 150 354 1.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS19920 f05ac8c5a4beb9721775710de6ddabb5 94 Pfam PF00934 PE family 2 82 5.1E-28 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19920 f05ac8c5a4beb9721775710de6ddabb5 94 SUPERFAMILY SSF140459 8 79 2.88E-23 T 28-03-2018 CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 Pfam PF00005 ABC transporter 21 176 1.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 258 5.8E-113 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 Gene3D G3DSA:3.40.50.300 1 256 1.3E-56 T 28-03-2018 CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 SMART SM00382 29 223 5.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS04450 37e293d92d1dd8ba228ceea9e0565353 258 SUPERFAMILY SSF52540 5 245 1.61E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 SUPERFAMILY SSF82866 810 1034 3.14E-22 T 28-03-2018 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 Gene3D G3DSA:1.10.287.950 466 743 0.022 T 28-03-2018 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 Pfam PF03176 MMPL family 677 1047 8.9E-106 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 Pfam PF03176 MMPL family 75 401 5.2E-101 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 Gene3D G3DSA:1.20.1640.10 814 1031 5.2E-19 T 28-03-2018 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 Gene3D G3DSA:1.20.1640.10 169 375 8.4E-28 T 28-03-2018 CP478_RS20880 56699566a4779f4947c4136bffd962cd 1089 SUPERFAMILY SSF82866 156 376 2.09E-26 T 28-03-2018 CP478_RS11480 5d6d31fa59dc39507f14753bc0675a6c 248 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 234 1.9E-116 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CP478_RS11480 5d6d31fa59dc39507f14753bc0675a6c 248 Gene3D G3DSA:3.60.20.10 8 240 9.7E-42 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11480 5d6d31fa59dc39507f14753bc0675a6c 248 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 238 47.301 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CP478_RS11480 5d6d31fa59dc39507f14753bc0675a6c 248 SUPERFAMILY SSF56235 10 233 1.53E-44 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11480 5d6d31fa59dc39507f14753bc0675a6c 248 Pfam PF00227 Proteasome subunit 25 205 4.8E-40 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 SUPERFAMILY SSF50022 466 512 1.83E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 Gene3D G3DSA:3.60.15.10 1 247 1.6E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 Pfam PF00355 Rieske [2Fe-2S] domain 466 506 2.8E-7 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 Pfam PF13483 Beta-lactamase superfamily domain 2 72 1.0E-6 T 28-03-2018 CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 Gene3D G3DSA:2.102.10.10 463 514 2.0E-9 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 SUPERFAMILY SSF56281 108 236 1.49E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20855 18b82e12a0ae8b9a7a2914d5bd5f84c9 516 SUPERFAMILY SSF56281 2 75 1.49E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02560 7822ccbfdf9f8ce7f32fc82404e41107 280 Pfam PF00795 Carbon-nitrogen hydrolase 2 258 6.5E-39 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS02560 7822ccbfdf9f8ce7f32fc82404e41107 280 SUPERFAMILY SSF56317 1 265 3.4E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS02560 7822ccbfdf9f8ce7f32fc82404e41107 280 Gene3D G3DSA:3.60.110.10 1 272 3.2E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS02560 7822ccbfdf9f8ce7f32fc82404e41107 280 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CP478_RS21250 638977bf9650227bc900e7a87c6b0ada 341 SUPERFAMILY SSF52540 90 304 2.86E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21250 638977bf9650227bc900e7a87c6b0ada 341 Gene3D G3DSA:3.40.50.300 84 321 1.7E-25 T 28-03-2018 CP478_RS00095 034bcb29f83a2dd8abbf774c21c8588c 491 Gene3D G3DSA:3.40.710.10 143 491 5.6E-83 T 28-03-2018 CP478_RS00095 034bcb29f83a2dd8abbf774c21c8588c 491 SUPERFAMILY SSF56601 128 490 4.78E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS00095 034bcb29f83a2dd8abbf774c21c8588c 491 Pfam PF00905 Penicillin binding protein transpeptidase domain 160 484 1.3E-75 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CP478_RS00095 034bcb29f83a2dd8abbf774c21c8588c 491 Gene3D G3DSA:3.90.1310.10 17 142 3.7E-13 T 28-03-2018 CP478_RS04000 80d4f44d8297d8e1f5f2341cfd241a31 182 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 179 2.1E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS04000 80d4f44d8297d8e1f5f2341cfd241a31 182 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 121 1.3E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS04000 80d4f44d8297d8e1f5f2341cfd241a31 182 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 7 179 4.4E-56 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CP478_RS04000 80d4f44d8297d8e1f5f2341cfd241a31 182 SUPERFAMILY SSF109854 5 126 2.87E-20 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS04000 80d4f44d8297d8e1f5f2341cfd241a31 182 Gene3D G3DSA:1.20.120.450 2 127 6.2E-19 T 28-03-2018 CP478_RS09645 a53beb5ab9b6798d945afd5bc106241c 414 SUPERFAMILY SSF51419 41 288 1.57E-18 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS09645 a53beb5ab9b6798d945afd5bc106241c 414 Gene3D G3DSA:3.20.20.10 42 294 6.8E-34 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS09645 a53beb5ab9b6798d945afd5bc106241c 414 Pfam PF01168 Alanine racemase, N-terminal domain 40 286 9.0E-10 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS07050 840224bb3fdea1da2d60ba0ac6a80476 521 Pfam PF10011 Predicted membrane protein (DUF2254) 69 438 5.9E-103 T 28-03-2018 IPR018723 Protein of unknown function DUF2254, membrane CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 436 1.2E-127 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 Pfam PF00344 SecY translocase 75 424 4.3E-113 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 Gene3D G3DSA:1.10.3370.10 1 441 3.0E-154 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 1.5E-100 T 28-03-2018 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 SUPERFAMILY SSF103491 2 431 5.23E-120 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 440 29.39 T 28-03-2018 IPR026593 Protein translocase subunit SecY CP478_RS03960 be0e5373b2a19512af129bf3cf8975e7 441 PIRSF PIRSF004557 1 441 2.7E-115 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 Pfam PF00107 Zinc-binding dehydrogenase 195 325 3.4E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 SUPERFAMILY SSF51735 157 332 2.68E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 368 8.3E-165 T 28-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 153 1.5E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 SUPERFAMILY SSF50129 320 367 1.18E-8 T 28-03-2018 IPR011032 GroES-like CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 Gene3D G3DSA:3.40.50.10730 182 307 3.5E-20 T 28-03-2018 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 Gene3D G3DSA:3.90.180.10 1 181 8.0E-50 T 28-03-2018 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 SMART SM00829 12 366 1.7E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS16880 bd68d670206cb79cf92ce2bc07148696 368 SUPERFAMILY SSF50129 1 191 6.54E-61 T 28-03-2018 IPR011032 GroES-like CP478_RS12640 89c7fda08fb52b0e35582ec1c4d5eed3 440 SUPERFAMILY SSF53850 42 435 3.04E-57 T 28-03-2018 CP478_RS12640 89c7fda08fb52b0e35582ec1c4d5eed3 440 Pfam PF01547 Bacterial extracellular solute-binding protein 51 351 1.3E-44 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CP478_RS12640 89c7fda08fb52b0e35582ec1c4d5eed3 440 Gene3D G3DSA:3.40.190.10 29 161 6.3E-24 T 28-03-2018 CP478_RS12640 89c7fda08fb52b0e35582ec1c4d5eed3 440 Gene3D G3DSA:3.40.190.10 162 440 2.0E-34 T 28-03-2018 CP478_RS10085 9f4008c3de002fa7bfb29e6c87333452 307 SUPERFAMILY SSF51679 3 305 1.06E-66 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS10085 9f4008c3de002fa7bfb29e6c87333452 307 Gene3D G3DSA:3.20.20.30 243 305 5.2E-7 T 28-03-2018 CP478_RS10085 9f4008c3de002fa7bfb29e6c87333452 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 11 233 2.1E-90 T 28-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CP478_RS10085 9f4008c3de002fa7bfb29e6c87333452 307 Pfam PF00296 Luciferase-like monooxygenase 21 242 5.3E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS10085 9f4008c3de002fa7bfb29e6c87333452 307 Gene3D G3DSA:3.20.20.30 7 242 1.2E-55 T 28-03-2018 CP478_RS01200 8704ab8df654d00399f567ac9d220a3c 262 SUPERFAMILY SSF52096 11 261 8.5E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS01200 8704ab8df654d00399f567ac9d220a3c 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 261 6.0E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS01200 8704ab8df654d00399f567ac9d220a3c 262 Gene3D G3DSA:1.10.12.10 220 262 5.0E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS01200 8704ab8df654d00399f567ac9d220a3c 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS01200 8704ab8df654d00399f567ac9d220a3c 262 Gene3D G3DSA:3.90.226.10 13 219 1.2E-60 T 28-03-2018 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 579 611 1.2E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.3E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Pfam PF00005 ABC transporter 25 182 5.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Pfam PF00005 ABC transporter 378 527 6.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 SUPERFAMILY SSF52540 4 252 8.54E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 3.1E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Gene3D G3DSA:3.40.50.300 1 333 3.1E-70 T 28-03-2018 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 Gene3D G3DSA:3.40.50.300 346 612 7.1E-70 T 28-03-2018 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 SUPERFAMILY SSF52540 350 599 3.51E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 SMART SM00382 386 577 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 SMART SM00382 33 232 7.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07005 7eb262126c0c98b9b9d1f7141f6a88fd 612 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS07765 9ffeed36d6ae13ff2203ba5051072ae7 157 SUPERFAMILY SSF50370 35 155 1.33E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain CP478_RS07765 9ffeed36d6ae13ff2203ba5051072ae7 157 Pfam PF00652 Ricin-type beta-trefoil lectin domain 37 153 1.9E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CP478_RS07765 9ffeed36d6ae13ff2203ba5051072ae7 157 Gene3D G3DSA:2.80.10.50 101 157 8.6E-8 T 28-03-2018 CP478_RS07765 9ffeed36d6ae13ff2203ba5051072ae7 157 Gene3D G3DSA:2.80.10.50 19 100 5.0E-10 T 28-03-2018 CP478_RS07765 9ffeed36d6ae13ff2203ba5051072ae7 157 SMART SM00458 35 156 1.1E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CP478_RS16055 427831fa6634480d5b9e62d0a383dbb2 422 SUPERFAMILY SSF52777 7 162 1.45E-20 T 28-03-2018 CP478_RS16055 427831fa6634480d5b9e62d0a383dbb2 422 Pfam PF00668 Condensation domain 20 147 7.8E-7 T 28-03-2018 IPR001242 Condensation domain CP478_RS16055 427831fa6634480d5b9e62d0a383dbb2 422 Gene3D G3DSA:3.30.559.10 8 182 5.4E-13 T 28-03-2018 CP478_RS16055 427831fa6634480d5b9e62d0a383dbb2 422 SUPERFAMILY SSF52777 182 416 4.11E-60 T 28-03-2018 CP478_RS16055 427831fa6634480d5b9e62d0a383dbb2 422 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 300 407 1.3E-25 T 28-03-2018 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 SUPERFAMILY SSF54913 1 112 3.5E-44 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 PIRSF PIRSF039144 1 112 5.5E-54 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 PRINTS PR00340 P-II protein signature 2 17 1.3E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 PRINTS PR00340 P-II protein signature 52 75 1.3E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 PRINTS PR00340 P-II protein signature 23 41 1.3E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 PRINTS PR00340 P-II protein signature 83 103 1.3E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 Gene3D G3DSA:3.30.70.120 1 109 5.0E-47 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 SMART SM00938 4 105 2.5E-60 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CP478_RS15940 2379b6f8ce7919d04401d37bd56bb8a9 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.2E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CP478_RS06490 36e62920859d63a50430da907a6366f0 359 Pfam PF08237 PE-PPE domain 79 316 2.3E-74 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS06490 36e62920859d63a50430da907a6366f0 359 Gene3D G3DSA:3.40.50.1820 25 318 5.5E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 Pfam PF00106 short chain dehydrogenase 10 203 3.9E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 SUPERFAMILY SSF51735 9 250 2.55E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.5E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS20710 7e30a9f6987a52a58a5dd952fa888479 254 Gene3D G3DSA:3.40.50.720 7 228 2.0E-33 T 28-03-2018 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 PIRSF PIRSF015592 1 217 6.0E-71 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 206 39.769 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 220 3.3E-101 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 SUPERFAMILY SSF53182 1 214 1.83E-54 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 135 151 1.5E-19 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 1.5E-19 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 165 177 1.5E-19 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 1.5E-19 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 Gene3D G3DSA:3.40.630.20 1 218 9.2E-43 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 Pfam PF01470 Pyroglutamyl peptidase 3 208 2.5E-83 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CP478_RS01710 a925c1cbb6c1e61ad3454fdab188e3bd 222 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 133 147 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CP478_RS18950 2102adb414f7ae94a10e0ad8cd43dac0 285 Gene3D G3DSA:3.20.20.30 129 281 1.8E-12 T 28-03-2018 CP478_RS18950 2102adb414f7ae94a10e0ad8cd43dac0 285 Gene3D G3DSA:3.20.20.30 23 128 1.6E-12 T 28-03-2018 CP478_RS18950 2102adb414f7ae94a10e0ad8cd43dac0 285 SUPERFAMILY SSF51679 26 279 3.87E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS18950 2102adb414f7ae94a10e0ad8cd43dac0 285 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 27 281 3.7E-114 T 28-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CP478_RS18950 2102adb414f7ae94a10e0ad8cd43dac0 285 Pfam PF00296 Luciferase-like monooxygenase 28 123 3.8E-12 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS19825 05d83292555177de1e4fa5457850c835 241 Gene3D G3DSA:3.90.550.10 3 237 4.3E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS19825 05d83292555177de1e4fa5457850c835 241 SUPERFAMILY SSF53448 13 222 8.23E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS19825 05d83292555177de1e4fa5457850c835 241 Pfam PF00535 Glycosyl transferase family 2 16 149 5.3E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS16240 8087f7e201d52ab871c16b5d2d11f6de 56 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 14 29 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CP478_RS16240 8087f7e201d52ab871c16b5d2d11f6de 56 Gene3D G3DSA:3.20.20.100 1 49 2.7E-7 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS16240 8087f7e201d52ab871c16b5d2d11f6de 56 SUPERFAMILY SSF51430 1 45 3.27E-8 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS05030 c4f9ca51f24d8a29918f34187730e5f4 193 Gene3D G3DSA:3.40.50.1390 47 192 1.1E-22 T 28-03-2018 CP478_RS05030 c4f9ca51f24d8a29918f34187730e5f4 193 SMART SM00857 52 187 8.7E-19 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS05030 c4f9ca51f24d8a29918f34187730e5f4 193 Pfam PF00239 Resolvase, N terminal domain 52 189 5.1E-20 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS05030 c4f9ca51f24d8a29918f34187730e5f4 193 SUPERFAMILY SSF53041 52 182 4.19E-21 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS05030 c4f9ca51f24d8a29918f34187730e5f4 193 Gene3D G3DSA:1.10.1660.20 1 44 3.3E-7 T 28-03-2018 CP478_RS13370 c009afb3538a17344e82e468143dae44 123 Pfam PF14017 Protein of unknown function (DUF4233) 18 117 4.6E-27 T 28-03-2018 IPR025327 Protein of unknown function DUF4233 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 2.4E-143 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 Pfam PF00483 Nucleotidyl transferase 9 276 5.3E-72 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 Gene3D G3DSA:3.90.550.10 2 280 1.2E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 46.799 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 SUPERFAMILY SSF51161 301 398 7.62E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 SUPERFAMILY SSF53448 342 358 1.1E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 SUPERFAMILY SSF53448 7 280 1.1E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS06645 150d1c3ca6b07d956da55ac55a38099d 404 Gene3D G3DSA:2.160.10.10 281 404 3.1E-11 T 28-03-2018 CP478_RS08825 31cad5d1324cb528603496cfe7803e86 468 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 16 273 7.4E-57 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CP478_RS08825 31cad5d1324cb528603496cfe7803e86 468 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 143 155 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CP478_RS08825 31cad5d1324cb528603496cfe7803e86 468 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 15 273 1.6E-38 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CP478_RS08825 31cad5d1324cb528603496cfe7803e86 468 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 279 14.973 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CP478_RS11420 9f6f64178556a42aebd64227f3cb0685 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.621 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CP478_RS11420 9f6f64178556a42aebd64227f3cb0685 452 PIRSF PIRSF018077 1 452 2.6E-187 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CP478_RS11420 9f6f64178556a42aebd64227f3cb0685 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 1.5E-242 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CP478_RS11420 9f6f64178556a42aebd64227f3cb0685 452 Pfam PF03136 Pup-ligase protein 4 422 3.7E-159 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CP478_RS03675 7e8a91aaeaf1d659270e283866a99460 124 Pfam PF11259 Protein of unknown function (DUF3060) 55 113 6.6E-22 T 28-03-2018 IPR021417 Protein of unknown function DUF3060 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 SUPERFAMILY SSF63867 343 422 4.84E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 SUPERFAMILY SSF53218 191 336 1.7E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 SUPERFAMILY SSF63882 2 190 1.31E-38 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Gene3D G3DSA:2.170.190.11 58 155 2.0E-27 T 28-03-2018 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 181 5.1E-38 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 SMART SM00852 194 333 2.7E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 191 329 4.0E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Gene3D G3DSA:3.40.980.10 164 340 4.4E-40 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Gene3D G3DSA:2.40.340.10 345 424 4.2E-21 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Pfam PF00994 Probable molybdopterin binding domain 195 332 3.5E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Gene3D G3DSA:3.90.105.10 22 57 1.9E-4 T 28-03-2018 CP478_RS05425 594fdca1ec513461628407dbe0b87f6c 426 Pfam PF03454 MoeA C-terminal region (domain IV) 347 422 2.5E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS03170 1f86c95b7ce051abbae206a5e56d7f85 508 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 312 8.5E-98 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03170 1f86c95b7ce051abbae206a5e56d7f85 508 Gene3D G3DSA:3.90.20.10 145 313 7.2E-4 T 28-03-2018 CP478_RS03170 1f86c95b7ce051abbae206a5e56d7f85 508 Pfam PF02470 MlaD protein 46 120 5.2E-12 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 Pfam PF00581 Rhodanese-like domain 149 266 5.1E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 Pfam PF00581 Rhodanese-like domain 9 118 1.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 SUPERFAMILY SSF52821 159 275 4.45E-36 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 SUPERFAMILY SSF52821 3 139 7.2E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 SMART SM00450 8 122 6.7E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 SMART SM00450 144 271 6.0E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 Gene3D G3DSA:3.40.250.10 157 277 5.0E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS04425 1f883907c749a8be904f730fcdc48889 277 Gene3D G3DSA:3.40.250.10 1 141 7.7E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 Pfam PF00581 Rhodanese-like domain 149 266 5.1E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 Pfam PF00581 Rhodanese-like domain 9 118 1.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 SUPERFAMILY SSF52821 159 275 4.45E-36 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 SUPERFAMILY SSF52821 3 139 7.2E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 SMART SM00450 8 122 6.7E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 SMART SM00450 144 271 6.0E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 Gene3D G3DSA:3.40.250.10 157 277 5.0E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17060 1f883907c749a8be904f730fcdc48889 277 Gene3D G3DSA:3.40.250.10 1 141 7.7E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 Pfam PF03054 tRNA methyl transferase 1 353 1.9E-118 T 28-03-2018 CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 SUPERFAMILY SSF52402 1 238 3.97E-47 T 28-03-2018 CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 353 1.1E-84 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 Gene3D G3DSA:3.40.50.620 1 206 9.4E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 Gene3D G3DSA:2.40.30.10 273 361 3.3E-17 T 28-03-2018 CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 Gene3D G3DSA:2.30.30.280 208 272 3.8E-15 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CP478_RS16545 a4ffae5cf0404e887e4cfa9ca5d7722e 367 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 354 35.545 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CP478_RS02430 3e2e351e9f240950273fe2ae309d2924 93 Gene3D G3DSA:2.30.30.110 1 85 1.2E-10 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS02430 3e2e351e9f240950273fe2ae309d2924 93 SUPERFAMILY SSF50118 2 64 5.45E-14 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS02430 3e2e351e9f240950273fe2ae309d2924 93 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 58 4.5E-11 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS02215 de56beb460e70516008850220c8be429 68 Gene3D G3DSA:3.10.20.30 1 68 3.2E-21 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS02215 de56beb460e70516008850220c8be429 68 SUPERFAMILY SSF54285 3 67 5.45E-12 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CP478_RS02215 de56beb460e70516008850220c8be429 68 Pfam PF02597 ThiS family 5 68 1.9E-12 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CP478_RS02215 de56beb460e70516008850220c8be429 68 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 68 3.6E-22 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 Gene3D G3DSA:3.40.50.620 155 295 2.6E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 Pfam PF00582 Universal stress protein family 10 148 3.1E-25 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 Pfam PF00582 Universal stress protein family 162 293 4.0E-26 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 PRINTS PR01438 Universal stress protein signature 159 177 8.4E-20 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 PRINTS PR01438 Universal stress protein signature 271 293 8.4E-20 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 PRINTS PR01438 Universal stress protein signature 253 265 8.4E-20 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 SUPERFAMILY SSF52402 10 152 1.34E-27 T 28-03-2018 CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 Gene3D G3DSA:3.40.50.620 1 148 2.0E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS10930 869cd2b4179f03e7e302f982c565c947 295 SUPERFAMILY SSF52402 161 293 8.37E-31 T 28-03-2018 CP478_RS11475 40300838373720e07354eb59a932fa89 243 SUPERFAMILY SSF140459 3 173 1.6E-59 T 28-03-2018 CP478_RS11475 40300838373720e07354eb59a932fa89 243 Gene3D G3DSA:1.10.287.1060 23 105 1.2E-9 T 28-03-2018 CP478_RS11475 40300838373720e07354eb59a932fa89 243 Pfam PF00823 PPE family 6 161 4.7E-57 T 28-03-2018 IPR000030 PPE family CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 SUPERFAMILY SSF52166 10 209 9.42E-72 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 Pfam PF00573 Ribosomal protein L4/L1 family 24 208 9.3E-65 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 24 209 4.8E-70 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 Gene3D G3DSA:3.40.1370.10 150 210 1.4E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 Gene3D G3DSA:3.40.1370.10 9 149 9.1E-51 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CP478_RS03810 ea98820f4ed8687bc1b4e72c479d92e0 223 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 16 215 32.518 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS17410 4d3d33ea1e5b9af9038679b8674b38c8 144 SUPERFAMILY SSF88723 4 126 3.92E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS17410 4d3d33ea1e5b9af9038679b8674b38c8 144 Gene3D G3DSA:3.40.50.1010 2 144 7.4E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS17410 4d3d33ea1e5b9af9038679b8674b38c8 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 139 13.002 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS17410 4d3d33ea1e5b9af9038679b8674b38c8 144 Pfam PF01850 PIN domain 4 127 3.3E-12 T 28-03-2018 IPR002716 PIN domain CP478_RS13185 c547bafe43212d182affc74a316976f6 298 SUPERFAMILY SSF47781 228 294 1.89E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CP478_RS13185 c547bafe43212d182affc74a316976f6 298 Pfam PF10531 SLBB domain 139 192 3.1E-8 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 Gene3D G3DSA:1.10.150.20 238 254 0.11 T 28-03-2018 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 238 295 5.6E-15 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CP478_RS13185 c547bafe43212d182affc74a316976f6 298 Gene3D G3DSA:1.10.150.310 255 298 7.4E-15 T 28-03-2018 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 SMART SM00278 276 295 230.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 SMART SM00278 246 265 0.0061 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 Gene3D G3DSA:3.10.560.10 131 237 5.2E-8 T 28-03-2018 CP478_RS13185 c547bafe43212d182affc74a316976f6 298 Pfam PF12836 Helix-hairpin-helix motif 235 296 3.8E-20 T 28-03-2018 CP478_RS12435 348c67659a96f82891290aa3c3d8b7ab 260 Hamap MF_00319 CDP-diacylglycerol pyrophosphatase [cdh]. 7 259 44.261 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 CP478_RS12435 348c67659a96f82891290aa3c3d8b7ab 260 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 41 257 1.4E-69 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 CP478_RS12435 348c67659a96f82891290aa3c3d8b7ab 260 Gene3D G3DSA:3.30.428.30 39 257 1.8E-61 T 28-03-2018 CP478_RS12435 348c67659a96f82891290aa3c3d8b7ab 260 SUPERFAMILY SSF54197 41 257 1.04E-66 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS12435 348c67659a96f82891290aa3c3d8b7ab 260 PIRSF PIRSF001273 12 260 2.6E-108 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 SUPERFAMILY SSF56801 5 533 4.84E-114 T 28-03-2018 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 1.2E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Gene3D G3DSA:3.40.50.980 5 175 9.9E-41 T 28-03-2018 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Pfam PF00501 AMP-binding enzyme 13 430 8.4E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Gene3D G3DSA:3.30.300.30 434 541 3.0E-25 T 28-03-2018 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Gene3D G3DSA:2.30.38.10 347 430 3.4E-7 T 28-03-2018 CP478_RS19215 014be79152785ab31a7ff695839dfa6b 548 Gene3D G3DSA:3.40.50.980 176 346 4.0E-26 T 28-03-2018 CP478_RS08780 9deeea5da739d84bfc884d47dfb26e0e 267 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 13 267 2.1E-115 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CP478_RS08780 9deeea5da739d84bfc884d47dfb26e0e 267 SUPERFAMILY SSF51366 14 267 1.88E-79 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS08780 9deeea5da739d84bfc884d47dfb26e0e 267 Gene3D G3DSA:3.20.20.70 15 263 1.1E-64 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08780 9deeea5da739d84bfc884d47dfb26e0e 267 Pfam PF00977 Histidine biosynthesis protein 16 251 1.3E-86 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CP478_RS08780 9deeea5da739d84bfc884d47dfb26e0e 267 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 12 267 47.715 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 Gene3D G3DSA:1.10.3090.10 163 474 3.9E-66 T 28-03-2018 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 11 475 5.6E-259 T 28-03-2018 IPR014065 tRNA adenylyltransferase CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 Pfam PF01743 Poly A polymerase head domain 39 165 9.1E-32 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 SMART SM00471 264 419 2.0E-5 T 28-03-2018 IPR003607 HD/PDEase domain CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 SUPERFAMILY SSF81301 30 163 1.63E-33 T 28-03-2018 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 Gene3D G3DSA:3.30.460.10 12 162 5.1E-39 T 28-03-2018 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 193 252 5.4E-18 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 SUPERFAMILY SSF81891 165 475 7.46E-63 T 28-03-2018 CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 TIGRFAM TIGR00277 HDIG: HDIG domain 265 345 6.0E-21 T 28-03-2018 IPR006675 HDIG domain CP478_RS21345 30d49c469a305492fd05b8af328ef515 480 Pfam PF01966 HD domain 268 381 1.4E-14 T 28-03-2018 IPR006674 HD domain CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 SMART SM00487 164 393 3.3E-20 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 SUPERFAMILY SSF52540 149 266 5.55E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 SUPERFAMILY SSF52540 294 363 5.55E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 Pfam PF04851 Type III restriction enzyme, res subunit 166 363 1.6E-29 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 SUPERFAMILY SSF52980 20 149 1.45E-11 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 Pfam PF13156 Restriction endonuclease 34 151 1.2E-47 T 28-03-2018 CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 Gene3D G3DSA:3.40.1350.10 9 151 1.4E-20 T 28-03-2018 CP478_RS11050 094d3545018a5270b7cdd5d5e6fa441b 515 Gene3D G3DSA:3.40.50.300 152 384 1.7E-28 T 28-03-2018 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 8.1E-31 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 49.087 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 123 2.0E-68 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 73 140 5.4E-22 T 28-03-2018 IPR020603 MraZ domain CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 71 1.4E-20 T 28-03-2018 IPR020603 MraZ domain CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 SUPERFAMILY SSF89447 1 133 1.67E-42 T 28-03-2018 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 Gene3D G3DSA:2.10.260.10 1 27 9.4E-6 T 28-03-2018 CP478_RS11780 33c7db7dddd20649a73e430b1508e76f 143 Gene3D G3DSA:2.10.260.10 80 123 3.2E-5 T 28-03-2018 CP478_RS11680 d4e34881139f515cf1093e4b4c26957e 96 Pfam PF02325 YGGT family 10 88 3.2E-11 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 12 356 1.3E-127 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 9 356 4.5E-119 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 SUPERFAMILY SSF51726 8 356 2.62E-93 T 28-03-2018 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 9 357 44.686 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 25 34 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CP478_RS14685 fc5f5948ca533246838b82b0b58e764a 357 Gene3D G3DSA:3.20.20.210 1 357 6.8E-93 T 28-03-2018 CP478_RS03375 8ccf29d8d41c97b3077e3287eb404943 383 SMART SM01204 221 365 4.4E-30 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS03375 8ccf29d8d41c97b3077e3287eb404943 383 SMART SM00897 32 220 5.1E-34 T 28-03-2018 IPR013702 FIST domain, N-terminal CP478_RS03375 8ccf29d8d41c97b3077e3287eb404943 383 Pfam PF08495 FIST N domain 35 219 1.0E-26 T 28-03-2018 IPR013702 FIST domain, N-terminal CP478_RS03375 8ccf29d8d41c97b3077e3287eb404943 383 Pfam PF10442 FIST C domain 222 364 6.7E-25 T 28-03-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CP478_RS03375 8ccf29d8d41c97b3077e3287eb404943 383 PIRSF PIRSF018953 1 383 3.6E-138 T 28-03-2018 IPR016741 Uncharacterised conserved protein UCP018953 CP478_RS21135 30a1cdf3396abbbdf70f6e2786e28261 283 Pfam PF14011 EspG family 22 258 6.6E-54 T 28-03-2018 IPR025734 EspG family CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 SMART SM00382 34 220 4.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 SUPERFAMILY SSF52540 9 223 9.57E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 Gene3D G3DSA:3.40.50.300 6 274 6.9E-57 T 28-03-2018 CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 Pfam PF13732 Domain of unknown function (DUF4162) 217 294 1.2E-6 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 Pfam PF00005 ABC transporter 25 163 9.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS06670 d7acc77dfc1699c9143d1fc0827bdf03 311 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 Gene3D G3DSA:1.10.10.10 3 100 4.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 SUPERFAMILY SSF46785 7 89 1.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 SMART SM00418 12 91 1.1E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.7E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.7E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 2.7E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS00455 da7f3e36d9c91580c1c4687805674428 114 Pfam PF12840 Helix-turn-helix domain 12 70 3.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13180 193bf839eca80da7004f532517a8e22d 514 Pfam PF03772 Competence protein 221 485 3.0E-44 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CP478_RS13180 193bf839eca80da7004f532517a8e22d 514 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 243 409 1.5E-14 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 ProSitePatterns PS00057 Ribosomal protein S18 signature. 30 53 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 Gene3D G3DSA:4.10.640.10 1 84 6.3E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 TIGRFAM TIGR00165 S18: ribosomal protein bS18 16 81 2.6E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 SUPERFAMILY SSF46911 10 81 2.09E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 Pfam PF01084 Ribosomal protein S18 28 77 2.0E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 82 20.386 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 30 81 3.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 PRINTS PR00974 Ribosomal protein S18 family signature 37 47 1.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 PRINTS PR00974 Ribosomal protein S18 family signature 69 79 1.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 PRINTS PR00974 Ribosomal protein S18 family signature 47 54 1.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00300 fcb73367463159b269ce9941688bbea8 84 PRINTS PR00974 Ribosomal protein S18 family signature 55 69 1.4E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 1.9E-126 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.279 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 Pfam PF04551 GcpE protein 21 361 7.0E-132 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 SUPERFAMILY SSF56014 276 360 6.21E-12 T 28-03-2018 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 PIRSF PIRSF004640 12 373 2.6E-143 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 SUPERFAMILY SSF51717 46 219 4.63E-9 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CP478_RS15680 99ff00182648c71402b926b8bee60df4 387 Gene3D G3DSA:3.20.20.120 25 158 4.1E-18 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 Gene3D G3DSA:1.10.443.10 109 292 2.3E-44 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 55.573 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 Gene3D G3DSA:1.10.150.130 1 108 1.5E-24 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 Pfam PF00589 Phage integrase family 109 283 8.6E-49 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 SUPERFAMILY SSF56349 8 289 1.88E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS15815 cbbcb258da7258657408341bbe1e2f9d 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 87 1.6E-21 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CP478_RS00100 da5a46a6d8180da802ce4cb33ddc77c0 469 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 402 426 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CP478_RS00100 da5a46a6d8180da802ce4cb33ddc77c0 469 Pfam PF01098 Cell cycle protein 81 444 5.5E-105 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 SUPERFAMILY SSF46689 18 96 1.65E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 SUPERFAMILY SSF48498 100 193 3.22E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 2.7E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 Gene3D G3DSA:1.10.10.60 2 73 3.4E-21 T 28-03-2018 CP478_RS13700 4019e75e175802543b8a67c06532bc2d 215 Gene3D G3DSA:1.10.357.10 74 215 1.4E-21 T 28-03-2018 CP478_RS06520 f8b8f3e36b19e936c175d8125388771c 292 Pfam PF12697 Alpha/beta hydrolase family 45 281 6.2E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS06520 f8b8f3e36b19e936c175d8125388771c 292 Gene3D G3DSA:3.40.50.1820 23 292 2.2E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06520 f8b8f3e36b19e936c175d8125388771c 292 SUPERFAMILY SSF53474 19 290 4.3E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01580 e2d8a18f4fc531810f3213028b1f1f10 400 Pfam PF00561 alpha/beta hydrolase fold 170 301 1.1E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS01580 e2d8a18f4fc531810f3213028b1f1f10 400 Gene3D G3DSA:3.40.50.1820 143 397 2.9E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01580 e2d8a18f4fc531810f3213028b1f1f10 400 SUPERFAMILY SSF53474 128 394 4.4E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 Pfam PF00557 Metallopeptidase family M24 154 356 1.3E-61 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 SUPERFAMILY SSF55920 145 372 3.93E-74 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 Gene3D G3DSA:3.40.350.10 2 143 3.5E-15 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 302 314 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 146 4.6E-11 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 Gene3D G3DSA:3.90.230.10 145 372 7.4E-73 T 28-03-2018 CP478_RS11380 c1400ae65e94207f9a44b510d640401d 375 SUPERFAMILY SSF53092 4 144 1.02E-14 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CP478_RS03205 769c1e528b6a00d6c464fc6c444e321c 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 7.2E-14 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CP478_RS03205 769c1e528b6a00d6c464fc6c444e321c 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 43 1.7E-7 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CP478_RS03205 769c1e528b6a00d6c464fc6c444e321c 78 Gene3D G3DSA:2.10.260.10 3 45 3.5E-10 T 28-03-2018 CP478_RS03205 769c1e528b6a00d6c464fc6c444e321c 78 SUPERFAMILY SSF89447 3 43 1.44E-9 T 28-03-2018 CP478_RS03205 769c1e528b6a00d6c464fc6c444e321c 78 SMART SM00966 3 48 1.3E-7 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 2.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 Pfam PF00106 short chain dehydrogenase 16 218 7.8E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 7.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 7.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 7.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 SUPERFAMILY SSF51735 9 299 2.57E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00380 ae898f4a21835252e4fd54810345f471 303 Gene3D G3DSA:3.40.50.720 1 302 1.7E-61 T 28-03-2018 CP478_RS01105 a922ef2d6d78fd1b1d8177e864359f1b 136 TIGRFAM TIGR04530 hemophoreRv0203: hemophore 16 133 8.7E-61 T 28-03-2018 IPR030937 Hemophore Rv0203 GO:0015886|GO:0020037 CP478_RS01105 a922ef2d6d78fd1b1d8177e864359f1b 136 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 41 117 1.9E-23 T 28-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 CP478_RS01105 a922ef2d6d78fd1b1d8177e864359f1b 136 Pfam PF16525 Haemophore, haem-binding 39 115 1.4E-26 T 28-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 SUPERFAMILY SSF52096 11 225 1.27E-51 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 SUPERFAMILY SSF52096 239 491 6.22E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 Pfam PF01039 Carboxyl transferase domain 14 479 2.5E-93 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 Gene3D G3DSA:3.90.226.10 2 230 5.0E-42 T 28-03-2018 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 193 202 5.4E-24 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 71 85 5.4E-24 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 105 123 5.4E-24 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 5.4E-24 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 159 5.4E-24 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CP478_RS04930 4000340be306ee09d2a252d3c4a81b7b 495 Gene3D G3DSA:3.90.226.10 231 489 5.6E-31 T 28-03-2018 CP478_RS03650 1955a3e5c94c2848a95542e6868df8af 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 205 4.2E-42 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS03650 1955a3e5c94c2848a95542e6868df8af 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS03650 1955a3e5c94c2848a95542e6868df8af 263 SUPERFAMILY SSF52096 1 244 8.48E-69 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03650 1955a3e5c94c2848a95542e6868df8af 263 Gene3D G3DSA:3.90.226.10 1 259 2.0E-62 T 28-03-2018 CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 194 1.3E-57 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 SUPERFAMILY SSF142695 202 329 5.1E-27 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 Pfam PF00925 GTP cyclohydrolase II 207 292 8.5E-21 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 PIRSF PIRSF001259 3 352 4.1E-113 T 28-03-2018 CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 Gene3D G3DSA:3.90.870.10 2 208 3.3E-61 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS10555 354b6b53dfbd38aa4d326aacdc63cb03 353 SUPERFAMILY SSF55821 7 201 8.93E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS16915 a3a434c13efe6e1d6acd8223745e3600 563 Pfam PF01734 Patatin-like phospholipase 182 420 5.4E-18 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS16915 a3a434c13efe6e1d6acd8223745e3600 563 SUPERFAMILY SSF52151 356 502 4.45E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16915 a3a434c13efe6e1d6acd8223745e3600 563 SUPERFAMILY SSF52151 180 314 4.45E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS16915 a3a434c13efe6e1d6acd8223745e3600 563 Gene3D G3DSA:3.40.1090.10 166 445 9.4E-20 T 28-03-2018 CP478_RS20530 a2e7b0bde714e9556251e9e818ff5165 315 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 41 305 1.5E-51 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CP478_RS20530 a2e7b0bde714e9556251e9e818ff5165 315 SUPERFAMILY SSF53850 41 309 4.61E-48 T 28-03-2018 CP478_RS20530 a2e7b0bde714e9556251e9e818ff5165 315 Gene3D G3DSA:3.40.190.10 36 157 6.3E-18 T 28-03-2018 CP478_RS20530 a2e7b0bde714e9556251e9e818ff5165 315 Gene3D G3DSA:3.40.190.120 158 249 1.3E-26 T 28-03-2018 CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 SMART SM00448 6 116 1.1E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 Pfam PF00072 Response regulator receiver domain 8 117 3.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 Gene3D G3DSA:1.10.10.10 124 228 6.4E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 SUPERFAMILY SSF52172 6 182 4.55E-44 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 8.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 SMART SM00862 149 225 2.6E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS17800 b3a201e66422beb82bb7ff93a785a6a2 228 Gene3D G3DSA:3.40.50.2300 1 123 2.5E-37 T 28-03-2018 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 SUPERFAMILY SSF54862 3 100 2.93E-17 T 28-03-2018 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 PRINTS PR00354 7Fe ferredoxin signature 9 19 7.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 PRINTS PR00354 7Fe ferredoxin signature 19 29 7.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 PRINTS PR00354 7Fe ferredoxin signature 35 52 7.7E-15 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 Pfam PF00037 4Fe-4S binding domain 34 56 1.0E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 Gene3D G3DSA:3.30.70.20 2 44 3.0E-8 T 28-03-2018 CP478_RS10940 d2e4c90d9086654911c38c72c6c1311a 114 Gene3D G3DSA:3.30.70.20 45 86 1.2E-6 T 28-03-2018 CP478_RS00470 12c6964a67a434c14f81c4093e1ac5e1 316 Pfam PF00146 NADH dehydrogenase 13 305 5.5E-41 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS15095 7d4123234e1baeba35af82a153c65b78 91 SUPERFAMILY SSF116734 2 89 2.13E-11 T 28-03-2018 CP478_RS15095 7d4123234e1baeba35af82a153c65b78 91 Gene3D G3DSA:3.90.220.20 1 91 3.5E-4 T 28-03-2018 CP478_RS19265 f7f1eb0ef1d38d799c0e79a4bbcd71ae 174 SUPERFAMILY SSF51161 1 155 7.35E-40 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS19265 f7f1eb0ef1d38d799c0e79a4bbcd71ae 174 Gene3D G3DSA:2.160.10.10 1 166 5.0E-34 T 28-03-2018 CP478_RS19265 f7f1eb0ef1d38d799c0e79a4bbcd71ae 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 1.8E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS06085 1858f4b65d97c656a4aeca8eaad5d62b 335 Gene3D G3DSA:3.40.50.1220 26 311 6.3E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS06085 1858f4b65d97c656a4aeca8eaad5d62b 335 Pfam PF02401 LytB protein 28 305 8.6E-89 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS06085 1858f4b65d97c656a4aeca8eaad5d62b 335 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 26 309 36.648 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS06085 1858f4b65d97c656a4aeca8eaad5d62b 335 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 28 307 5.1E-97 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Pfam PF13185 GAF domain 231 370 8.4E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Pfam PF13185 GAF domain 62 200 2.1E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SMART SM00065 63 210 5.5E-27 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SMART SM00065 231 379 7.0E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SUPERFAMILY SSF55781 45 228 3.05E-39 T 28-03-2018 IPR029016 GAF domain-like CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SUPERFAMILY SSF55874 468 576 1.96E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Gene3D G3DSA:3.30.565.10 454 578 1.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Gene3D G3DSA:3.30.450.40 58 209 2.3E-31 T 28-03-2018 IPR029016 GAF domain-like CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 494 548 1.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SMART SM00387 488 578 3.4E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Pfam PF07730 Histidine kinase 387 448 1.8E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 Gene3D G3DSA:3.30.450.40 210 383 4.4E-21 T 28-03-2018 IPR029016 GAF domain-like CP478_RS17145 a02e78bd2377b270efbc704cfd53d92f 578 SUPERFAMILY SSF55781 212 397 1.59E-20 T 28-03-2018 IPR029016 GAF domain-like CP478_RS11545 a95dc5ff7b232627e84be40a4bd6ca15 93 SUPERFAMILY SSF101386 8 93 2.43E-20 T 28-03-2018 CP478_RS11545 a95dc5ff7b232627e84be40a4bd6ca15 93 Gene3D G3DSA:1.10.287.1080 1 93 4.2E-15 T 28-03-2018 CP478_RS11545 a95dc5ff7b232627e84be40a4bd6ca15 93 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 7 93 18.109 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CP478_RS11545 a95dc5ff7b232627e84be40a4bd6ca15 93 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 11 93 2.9E-22 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CP478_RS11545 a95dc5ff7b232627e84be40a4bd6ca15 93 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 1.2E-7 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 Pfam PF12697 Alpha/beta hydrolase family 15 250 7.3E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00412 Epoxide hydrolase signature 234 256 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00412 Epoxide hydrolase signature 83 96 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00412 Epoxide hydrolase signature 40 55 8.0E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 Gene3D G3DSA:3.40.50.1820 1 262 1.5E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 SUPERFAMILY SSF53474 3 258 8.61E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 5.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 5.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS02965 b3817b576c21b830bf112e79011755f1 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 5.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 SMART SM00382 32 227 2.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 Pfam PF00005 ABC transporter 24 172 4.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 278 295 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 Pfam PF00027 Cyclic nucleotide-binding domain 229 311 1.1E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 SMART SM00100 208 328 6.0E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 SUPERFAMILY SSF51206 228 314 1.83E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 PRINTS PR00103 cAMP-dependent protein kinase signature 246 260 2.1E-9 T 28-03-2018 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 PRINTS PR00103 cAMP-dependent protein kinase signature 276 285 2.1E-9 T 28-03-2018 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 PRINTS PR00103 cAMP-dependent protein kinase signature 288 299 2.1E-9 T 28-03-2018 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 PRINTS PR00103 cAMP-dependent protein kinase signature 231 245 2.1E-9 T 28-03-2018 CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 Gene3D G3DSA:2.60.120.10 238 322 1.5E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 SUPERFAMILY SSF52540 4 229 2.38E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14060 9d0224bb39998c33a4a033943441d070 330 Gene3D G3DSA:3.40.50.300 2 237 3.8E-60 T 28-03-2018 CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 Gene3D G3DSA:3.30.565.10 295 494 3.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 Pfam PF12282 Signal transduction histidine kinase 4 150 1.3E-43 T 28-03-2018 IPR022066 Signal transduction histidine kinase CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 SUPERFAMILY SSF55874 357 492 8.91E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 SMART SM00387 394 495 2.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 Pfam PF07568 Histidine kinase 300 367 1.1E-21 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 Gene3D G3DSA:3.30.450.20 153 294 1.1E-7 T 28-03-2018 CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 SUPERFAMILY SSF55785 179 291 5.68E-5 T 28-03-2018 IPR000014 PAS domain CP478_RS17650 013310ce30f5fb0c875f193df66fccb1 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 493 2.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS01420 cb06b8bd8ff370dd23f53fb1b0bae030 300 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 283 2.8E-75 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CP478_RS01420 cb06b8bd8ff370dd23f53fb1b0bae030 300 SUPERFAMILY SSF50891 175 283 8.53E-9 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS01420 cb06b8bd8ff370dd23f53fb1b0bae030 300 SMART SM00797 25 300 6.0E-107 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CP478_RS01420 cb06b8bd8ff370dd23f53fb1b0bae030 300 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 300 4.6E-125 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CP478_RS08205 c2d030c19814f6425db58573aea0ef6b 429 Gene3D G3DSA:3.40.710.10 31 390 1.2E-64 T 28-03-2018 CP478_RS08205 c2d030c19814f6425db58573aea0ef6b 429 Pfam PF00144 Beta-lactamase 45 382 7.9E-58 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS08205 c2d030c19814f6425db58573aea0ef6b 429 SUPERFAMILY SSF56601 274 386 5.47E-60 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS08205 c2d030c19814f6425db58573aea0ef6b 429 SUPERFAMILY SSF56601 29 238 5.47E-60 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS16515 40f1770ec7f55acd8d5e4e3d50f25f4c 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 3.9E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16515 40f1770ec7f55acd8d5e4e3d50f25f4c 96 SUPERFAMILY SSF140453 2 95 3.27E-21 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16515 40f1770ec7f55acd8d5e4e3d50f25f4c 96 Gene3D G3DSA:1.10.287.1060 1 96 2.6E-13 T 28-03-2018 CP478_RS16515 40f1770ec7f55acd8d5e4e3d50f25f4c 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 96 7.0E-49 T 28-03-2018 CP478_RS16515 40f1770ec7f55acd8d5e4e3d50f25f4c 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 91 7.0E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS20115 e5084ccd87eb34d27442e55e105bd0da 346 Gene3D G3DSA:3.40.50.1100 24 131 1.6E-24 T 28-03-2018 CP478_RS20115 e5084ccd87eb34d27442e55e105bd0da 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 305 3.0E-49 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS20115 e5084ccd87eb34d27442e55e105bd0da 346 Gene3D G3DSA:3.40.50.1100 132 322 5.1E-43 T 28-03-2018 CP478_RS20115 e5084ccd87eb34d27442e55e105bd0da 346 SUPERFAMILY SSF53686 12 326 1.03E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS11585 78268a54f18266acb071166125de994d 414 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 36 338 2.3E-82 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CP478_RS11585 78268a54f18266acb071166125de994d 414 Gene3D G3DSA:1.20.120.640 332 414 1.0E-16 T 28-03-2018 CP478_RS11585 78268a54f18266acb071166125de994d 414 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 414 6.7E-207 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CP478_RS11585 78268a54f18266acb071166125de994d 414 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 414 51.755 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CP478_RS11585 78268a54f18266acb071166125de994d 414 Gene3D G3DSA:3.40.50.620 2 331 9.3E-66 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11585 78268a54f18266acb071166125de994d 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 246 267 4.4E-25 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS11585 78268a54f18266acb071166125de994d 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 4.4E-25 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS11585 78268a54f18266acb071166125de994d 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 215 233 4.4E-25 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS11585 78268a54f18266acb071166125de994d 414 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 4.4E-25 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CP478_RS11585 78268a54f18266acb071166125de994d 414 SUPERFAMILY SSF52374 28 338 5.09E-66 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 SUPERFAMILY SSF143865 20 298 4.58E-68 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 SUPERFAMILY SSF144083 301 363 3.27E-19 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 Gene3D G3DSA:1.20.58.340 183 298 7.9E-29 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 65 366 1.4E-64 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 Gene3D G3DSA:3.30.460.20 27 180 1.9E-36 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 Gene3D G3DSA:1.20.58.340 299 366 1.4E-18 T 28-03-2018 CP478_RS06785 16d087d9b70874ca7d12aeb21a579ee8 366 Pfam PF01544 CorA-like Mg2+ transporter protein 68 361 4.9E-65 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CP478_RS18450 ccda77fd7a77b687fbb0baab07d3b893 144 SUPERFAMILY SSF50475 7 140 2.99E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS18450 ccda77fd7a77b687fbb0baab07d3b893 144 TIGRFAM TIGR03667 Rv3369: PPOX class probable F420-dependent enzyme, Rv3369 family 12 138 2.1E-53 T 28-03-2018 IPR019966 F420-dependent enzyme, PPOX class, family Rv3369, probable CP478_RS18450 ccda77fd7a77b687fbb0baab07d3b893 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 96 5.8E-12 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS18450 ccda77fd7a77b687fbb0baab07d3b893 144 Gene3D G3DSA:2.30.110.10 3 134 8.6E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 Gene3D G3DSA:3.30.950.10 121 235 2.5E-26 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 1.4E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 Gene3D G3DSA:3.40.1010.10 1 120 1.6E-28 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 SUPERFAMILY SSF53790 2 234 1.09E-64 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 242 3.0E-90 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CP478_RS11290 c30d05293dfc05747a412fb87e2e3923 251 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS16655 0586e4265458b229b8e76f6c70ebc170 359 Pfam PF01497 Periplasmic binding protein 92 332 3.6E-17 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CP478_RS16655 0586e4265458b229b8e76f6c70ebc170 359 Gene3D G3DSA:3.40.50.1980 79 190 5.1E-24 T 28-03-2018 CP478_RS16655 0586e4265458b229b8e76f6c70ebc170 359 SUPERFAMILY SSF53807 83 341 2.79E-43 T 28-03-2018 CP478_RS16655 0586e4265458b229b8e76f6c70ebc170 359 Gene3D G3DSA:3.40.50.1980 191 353 3.6E-23 T 28-03-2018 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 Pfam PF00743 Flavin-binding monooxygenase-like 8 337 6.7E-21 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 SUPERFAMILY SSF51905 275 453 5.61E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 Gene3D G3DSA:3.50.50.60 6 162 5.4E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 Gene3D G3DSA:3.50.50.60 163 484 1.5E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 SUPERFAMILY SSF51905 5 225 4.66E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.1E-6 T 28-03-2018 CP478_RS04870 5a5b8b3290fc8c444b9420bfe7e655ab 495 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 3.1E-6 T 28-03-2018 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 624 40.386 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 SUPERFAMILY SSF56235 2 235 6.52E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Pfam PF13522 Glutamine amidotransferase domain 66 199 1.5E-20 T 28-03-2018 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Pfam PF01380 SIS domain 473 603 2.8E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Pfam PF01380 SIS domain 301 426 1.7E-35 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Gene3D G3DSA:3.40.50.10490 470 622 1.5E-45 T 28-03-2018 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Gene3D G3DSA:3.60.20.10 2 250 1.2E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 SUPERFAMILY SSF53697 257 624 2.69E-106 T 28-03-2018 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 Gene3D G3DSA:3.40.50.10490 251 469 8.8E-67 T 28-03-2018 CP478_RS18810 27406262ceac34cea97390c25687e1bd 624 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 624 7.0E-248 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 SUPERFAMILY SSF51905 364 557 5.73E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 SUPERFAMILY SSF51905 668 751 5.73E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Pfam PF00970 Oxidoreductase FAD-binding domain 108 202 1.1E-20 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 PRINTS PR00410 Phenol hydroxylase reductase family signature 211 230 1.2E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 1.2E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 PRINTS PR00410 Phenol hydroxylase reductase family signature 135 147 1.2E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 PRINTS PR00410 Phenol hydroxylase reductase family signature 152 159 1.2E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Pfam PF00175 Oxidoreductase NAD-binding domain 212 314 3.8E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 84 2.9E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Gene3D G3DSA:3.50.50.60 363 741 4.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 SUPERFAMILY SSF52343 205 333 6.29E-32 T 28-03-2018 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Gene3D G3DSA:3.10.20.30 2 100 1.7E-18 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Gene3D G3DSA:2.40.30.10 105 203 2.1E-17 T 28-03-2018 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 SUPERFAMILY SSF54292 5 91 8.78E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 Gene3D G3DSA:3.40.50.80 206 338 8.1E-26 T 28-03-2018 CP478_RS10540 3f4df50e248252f815c92f64c55a292c 839 SUPERFAMILY SSF63380 107 202 1.25E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 237 253 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 299 318 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 652 674 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 270 283 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 685 695 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 600 618 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 PRINTS PR00985 Leucyl-tRNA synthetase signature 164 181 3.5E-53 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Gene3D G3DSA:3.90.740.10 313 502 6.1E-46 T 28-03-2018 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Pfam PF08264 Anticodon-binding domain of tRNA 818 933 1.4E-12 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 SUPERFAMILY SSF52374 35 184 3.38E-101 T 28-03-2018 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 SUPERFAMILY SSF52374 516 787 3.38E-101 T 28-03-2018 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 SUPERFAMILY SSF52374 232 310 3.38E-101 T 28-03-2018 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Pfam PF09334 tRNA synthetases class I (M) 76 182 6.3E-12 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 305 504 1.1E-54 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 80 90 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 SUPERFAMILY SSF47323 782 969 1.87E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Gene3D G3DSA:1.10.730.10 768 906 5.7E-23 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 SUPERFAMILY SSF50677 329 513 2.62E-43 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 29 969 21.389 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 231 969 1.9E-214 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Gene3D G3DSA:3.40.50.620 503 767 3.2E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS00230 0eff1e8e0036bd527f6765d753b42718 969 Gene3D G3DSA:3.40.50.620 26 312 2.5E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 SUPERFAMILY SSF50249 182 303 1.71E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 Gene3D G3DSA:2.40.50.140 237 298 3.3E-18 T 28-03-2018 CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 Gene3D G3DSA:3.10.129.10 7 179 4.5E-29 T 28-03-2018 CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 Pfam PF13452 N-terminal half of MaoC dehydratase 26 159 2.2E-16 T 28-03-2018 CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 234 295 2.9E-20 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CP478_RS19360 d03972a5f1d7ab6181a895b36a4d0667 311 SUPERFAMILY SSF54637 23 174 3.55E-19 T 28-03-2018 IPR029069 HotDog domain CP478_RS11215 d98a2fd213757f6997abc456ea5752a8 54 Pfam PF00471 Ribosomal protein L33 9 54 3.2E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11215 d98a2fd213757f6997abc456ea5752a8 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.263 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11215 d98a2fd213757f6997abc456ea5752a8 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 9.2E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11215 d98a2fd213757f6997abc456ea5752a8 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11215 d98a2fd213757f6997abc456ea5752a8 54 SUPERFAMILY SSF57829 4 54 7.32E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 197 216 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 329 348 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 534 551 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 446 464 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 179 197 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 301 317 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 505 520 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 102 127 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 468 486 1.6E-66 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 Pfam PF01019 Gamma-glutamyltranspeptidase 95 636 7.9E-154 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CP478_RS13055 943923007ee91eed8e46450c4530d475 643 SUPERFAMILY SSF56235 72 640 8.49E-147 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.8E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 SMART SM00878 338 444 1.0E-46 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Gene3D G3DSA:3.30.1490.20 130 202 3.1E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Gene3D G3DSA:3.30.470.20 204 447 5.8E-101 T 28-03-2018 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 5.4E-82 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 610 627 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 SUPERFAMILY SSF52440 1 113 5.76E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Pfam PF02785 Biotin carboxylase C-terminal domain 338 445 5.8E-33 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 SUPERFAMILY SSF51230 579 652 8.11E-19 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Gene3D G3DSA:3.40.50.20 1 129 8.8E-49 T 28-03-2018 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 SUPERFAMILY SSF56059 83 350 1.43E-64 T 28-03-2018 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 SUPERFAMILY SSF51246 333 447 6.28E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Gene3D G3DSA:2.40.50.100 584 654 1.0E-15 T 28-03-2018 CP478_RS13675 6ba629d83a1c1ccb60c44b9f76ad208d 654 Pfam PF00364 Biotin-requiring enzyme 587 652 5.2E-15 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Gene3D G3DSA:3.40.50.970 8 200 8.1E-44 T 28-03-2018 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Gene3D G3DSA:3.40.50.970 358 549 1.2E-40 T 28-03-2018 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 SUPERFAMILY SSF52518 14 193 6.87E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 539 1.3E-19 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 SUPERFAMILY SSF52467 178 349 2.19E-21 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 188 1.6E-31 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 210 332 8.7E-10 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 Gene3D G3DSA:3.40.50.1220 201 353 1.6E-14 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 SUPERFAMILY SSF52518 368 549 2.95E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 PIRSF PIRSF036565 9 560 3.1E-203 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 CP478_RS04660 89d6b2d254803765dec11f9f5fb34f5e 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 8.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 Gene3D G3DSA:1.10.260.40 45 98 6.3E-13 T 28-03-2018 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 SUPERFAMILY SSF46689 9 82 2.51E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS18640 ca6fe1e81549cc622fa0e903e32acaba 188 Gene3D G3DSA:1.10.10.60 1 44 1.8E-15 T 28-03-2018 CP478_RS06425 8440e10d91dff48c2ac8ff6ee4837bf1 303 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 8 296 1.3E-142 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS06425 8440e10d91dff48c2ac8ff6ee4837bf1 303 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 157 9.9E-28 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CP478_RS06425 8440e10d91dff48c2ac8ff6ee4837bf1 303 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 7 296 40.459 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CP478_RS06425 8440e10d91dff48c2ac8ff6ee4837bf1 303 SUPERFAMILY SSF102588 4 297 1.31E-82 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS06425 8440e10d91dff48c2ac8ff6ee4837bf1 303 Gene3D G3DSA:3.40.50.10320 1 303 4.7E-76 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS18720 74d8d45aca732f883d3423cb656e5a8b 211 Gene3D G3DSA:3.30.420.40 2 141 1.9E-34 T 28-03-2018 CP478_RS18720 74d8d45aca732f883d3423cb656e5a8b 211 SUPERFAMILY SSF53067 9 107 2.03E-21 T 28-03-2018 CP478_RS18720 74d8d45aca732f883d3423cb656e5a8b 211 Pfam PF00814 Glycoprotease family 40 145 2.0E-25 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18720 74d8d45aca732f883d3423cb656e5a8b 211 SUPERFAMILY SSF53067 115 198 2.98E-9 T 28-03-2018 CP478_RS18720 74d8d45aca732f883d3423cb656e5a8b 211 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 9 200 4.9E-46 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Gene3D G3DSA:2.40.50.140 381 507 1.1E-31 T 28-03-2018 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Hamap MF_00407 DNA ligase [lig]. 1 507 26.09 T 28-03-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 72 507 2.1E-79 T 28-03-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 SUPERFAMILY SSF56091 180 380 5.52E-43 T 28-03-2018 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Gene3D G3DSA:3.30.470.30 169 321 3.2E-30 T 28-03-2018 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 209 217 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Gene3D G3DSA:3.30.1490.70 322 380 1.8E-15 T 28-03-2018 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Pfam PF04675 DNA ligase N terminus 70 140 6.0E-9 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Pfam PF04679 ATP dependent DNA ligase C terminal region 399 492 1.3E-10 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 Pfam PF01068 ATP dependent DNA ligase domain 186 380 1.2E-47 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 SUPERFAMILY SSF50249 382 507 1.51E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS16755 afc89ab5a685bb8cde217b166710700f 507 SUPERFAMILY SSF117018 7 197 2.35E-27 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CP478_RS18485 20367632c031ea26940f875b291663b6 475 Gene3D G3DSA:3.90.1300.10 13 475 1.1E-129 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS18485 20367632c031ea26940f875b291663b6 475 ProSitePatterns PS00571 Amidases signature. 164 195 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CP478_RS18485 20367632c031ea26940f875b291663b6 475 SUPERFAMILY SSF75304 17 474 2.62E-124 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS18485 20367632c031ea26940f875b291663b6 475 Pfam PF01425 Amidase 38 455 1.9E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS19310 264fab47cb26e999d4dbfb7ed943fa5d 406 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 325 402 6.4E-15 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS19310 264fab47cb26e999d4dbfb7ed943fa5d 406 Gene3D G3DSA:1.10.287.1060 23 104 3.8E-7 T 28-03-2018 CP478_RS19310 264fab47cb26e999d4dbfb7ed943fa5d 406 SUPERFAMILY SSF140459 4 174 5.49E-64 T 28-03-2018 CP478_RS19310 264fab47cb26e999d4dbfb7ed943fa5d 406 Pfam PF00823 PPE family 7 163 6.9E-64 T 28-03-2018 IPR000030 PPE family CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 Gene3D G3DSA:3.30.1390.20 4 58 1.2E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 SUPERFAMILY SSF55129 1 58 6.28E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 PIRSF PIRSF002211 1 60 1.5E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 4.2E-20 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.556 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03910 3e272e3b58080ecd2201fb0a994f775f 65 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 9.2E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Gene3D G3DSA:2.40.30.10 210 322 2.3E-24 T 28-03-2018 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 SUPERFAMILY SSF50447 197 320 5.3E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Gene3D G3DSA:3.40.50.300 2 209 2.9E-32 T 28-03-2018 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Pfam PF00009 Elongation factor Tu GTP binding domain 3 212 1.2E-49 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Gene3D G3DSA:2.40.50.250 503 593 1.5E-31 T 28-03-2018 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 SUPERFAMILY SSF54980 419 533 1.15E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 139 3.4E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 SUPERFAMILY SSF54980 322 408 9.64E-8 T 28-03-2018 IPR035647 EF-G domain III/V-like CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Pfam PF03144 Elongation factor Tu domain 2 236 309 3.6E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Gene3D G3DSA:3.30.70.240 422 500 1.6E-17 T 28-03-2018 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Pfam PF00679 Elongation factor G C-terminus 417 501 6.5E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 SMART SM00838 416 504 0.0051 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 619 6.0E-267 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 Gene3D G3DSA:3.30.70.870 323 421 8.0E-23 T 28-03-2018 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.7E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS06400 4139c5eee5574abd2efd115e4e6fa1c6 628 SUPERFAMILY SSF52540 3 223 4.25E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 65 251 9.1E-80 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 253 37.493 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 67 252 5.0E-54 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 PIRSF PIRSF000857 2 254 2.3E-84 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 SUPERFAMILY SSF52402 69 217 4.9E-39 T 28-03-2018 CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 Gene3D G3DSA:3.40.50.620 69 254 7.6E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS13045 71fa592b8764a1887e517a3e5e1893e8 254 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 61 228 8.7E-46 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 Gene3D G3DSA:1.20.5.420 85 138 6.2E-17 T 28-03-2018 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 1.1E-79 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 23 43 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 44 64 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 3 22 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 65 85 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 128 149 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 107 127 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PRINTS PR00601 Bacterioferritin signature 86 106 3.4E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 Gene3D G3DSA:1.20.1260.10 1 77 1.3E-15 T 28-03-2018 IPR012347 Ferritin-related CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 SUPERFAMILY SSF47240 1 152 1.57E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 Pfam PF00210 Ferritin-like domain 10 143 3.4E-35 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CP478_RS10205 f59c169e6e5d823c64710b2725a0484c 159 PIRSF PIRSF002560 1 157 1.2E-64 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 SMART SM00926 4 58 7.4E-11 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Pfam PF00384 Molybdopterin oxidoreductase 61 430 2.2E-30 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 SUPERFAMILY SSF50692 612 745 6.56E-23 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:2.40.40.20 584 747 8.0E-19 T 28-03-2018 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 57 7.0E-10 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:3.40.50.740 367 422 1.6E-12 T 28-03-2018 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:1.20.910.10 452 579 0.0022 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:3.40.50.740 63 161 2.2E-14 T 28-03-2018 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Pfam PF01568 Molydopterin dinucleotide binding domain 634 734 8.9E-15 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 SUPERFAMILY SSF53706 6 482 2.62E-110 T 28-03-2018 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:3.40.228.10 162 366 2.8E-38 T 28-03-2018 CP478_RS01075 95d656758dc28f15a6b519d4fdcfc89f 748 Gene3D G3DSA:2.20.25.90 2 62 8.1E-11 T 28-03-2018 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 SUPERFAMILY SSF53901 263 385 1.7E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 Gene3D G3DSA:3.40.47.10 265 383 1.7E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 384 1.1E-121 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 Gene3D G3DSA:3.40.47.10 1 264 3.5E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 SUPERFAMILY SSF53901 4 263 3.51E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 Pfam PF00108 Thiolase, N-terminal domain 5 255 4.9E-57 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 PIRSF PIRSF000429 1 386 4.1E-113 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS19435 61b76270e3f36eae9630f1e2d896667d 386 Pfam PF02803 Thiolase, C-terminal domain 264 385 8.0E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS03150 009f05a1e8a36223c2d7b514ee861fd1 295 Pfam PF02405 Permease MlaE 76 279 1.2E-50 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS05275 e74149c0d326a4f9b865130670c87a5a 200 Pfam PF08044 Domain of unknown function (DUF1707) 18 69 8.2E-16 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.3E-75 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Gene3D G3DSA:2.40.50.140 65 126 1.5E-23 T 28-03-2018 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.793 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 SMART SM00841 129 184 1.3E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 5.2E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 SUPERFAMILY SSF50249 65 126 4.71E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 SUPERFAMILY SSF50104 3 63 7.82E-20 T 28-03-2018 IPR008991 Translation protein SH3-like domain CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Gene3D G3DSA:2.40.50.140 129 184 2.6E-26 T 28-03-2018 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 5.9E-26 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Gene3D G3DSA:2.30.30.30 2 61 2.2E-25 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 PIRSF PIRSF005901 1 186 1.2E-65 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 SMART SM01185 67 121 3.8E-27 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 SUPERFAMILY SSF50249 128 185 4.11E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS13890 939c92bfe4ed1f5d4b35001d63d50724 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.2E-21 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CP478_RS06540 7caa78660b8cc5dc4531d6fa865c12ec 421 Pfam PF13556 PucR C-terminal helix-turn-helix domain 345 395 7.6E-11 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS06540 7caa78660b8cc5dc4531d6fa865c12ec 421 Gene3D G3DSA:1.10.10.60 282 378 3.8E-5 T 28-03-2018 CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 Gene3D G3DSA:3.40.50.790 68 148 3.9E-34 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 PIRSF PIRSF002155 1 227 1.8E-69 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 1.5E-100 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.1E-50 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 Gene3D G3DSA:3.30.190.20 149 228 7.0E-17 T 28-03-2018 CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 SUPERFAMILY SSF56808 6 226 3.14E-79 T 28-03-2018 IPR023674 Ribosomal protein L1-like CP478_RS03465 74172c395fc1a43201ee28524e81f48c 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.068 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 SMART SM01232 144 236 2.0E-34 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 284 7.1E-103 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 SUPERFAMILY SSF46946 143 233 2.06E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 285 40.017 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Gene3D G3DSA:1.10.8.50 136 285 3.6E-44 T 28-03-2018 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 144 231 3.1E-26 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 124 1.5E-34 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 SUPERFAMILY SSF57716 236 285 1.05E-16 T 28-03-2018 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 SMART SM00898 2 125 4.5E-41 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 ProSitePatterns PS01242 Zinc finger FPG-type signature. 260 284 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Pfam PF06827 Zinc finger found in FPG and IleRS 257 286 3.3E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 Gene3D G3DSA:3.20.190.10 2 135 1.6E-39 T 28-03-2018 CP478_RS15975 2557c96229ef628fa371db778bc46b06 289 SUPERFAMILY SSF81624 2 127 3.79E-32 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Pfam PF00501 AMP-binding enzyme 18 407 1.7E-53 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Gene3D G3DSA:2.30.38.10 308 400 2.1E-13 T 28-03-2018 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Gene3D G3DSA:3.30.300.30 402 511 1.5E-13 T 28-03-2018 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 493 1.2E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 SUPERFAMILY SSF56801 11 502 2.49E-91 T 28-03-2018 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Gene3D G3DSA:3.40.50.980 161 307 1.0E-30 T 28-03-2018 CP478_RS09545 6cd4ccf370aa5641851902f10a5cb8fb 532 Gene3D G3DSA:3.40.50.980 1 160 6.5E-22 T 28-03-2018 CP478_RS02755 b2bbebb4402eb40d5aa3a640b2b72630 511 Gene3D G3DSA:3.40.1800.10 333 400 7.9E-6 T 28-03-2018 CP478_RS02755 b2bbebb4402eb40d5aa3a640b2b72630 511 SMART SM00507 338 390 6.5E-5 T 28-03-2018 IPR003615 HNH nuclease CP478_RS02755 b2bbebb4402eb40d5aa3a640b2b72630 511 Pfam PF02720 Domain of unknown function (DUF222) 41 347 1.0E-92 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 Pfam PF01494 FAD binding domain 3 319 1.9E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 Gene3D G3DSA:3.50.50.60 1 319 9.2E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.3E-14 T 28-03-2018 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.3E-14 T 28-03-2018 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.3E-14 T 28-03-2018 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 2.3E-14 T 28-03-2018 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 SUPERFAMILY SSF51905 268 346 7.56E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06895 478fa84025053ff9e0da908d6b4aa4c0 372 SUPERFAMILY SSF51905 4 169 7.56E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 Pfam PF02674 Colicin V production protein 7 148 1.8E-12 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 Gene3D G3DSA:2.40.10.10 181 278 6.3E-21 T 28-03-2018 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 Pfam PF13365 Trypsin-like peptidase domain 220 357 5.9E-23 T 28-03-2018 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 Gene3D G3DSA:2.40.10.10 282 374 5.7E-16 T 28-03-2018 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 PRINTS PR00834 HtrA/DegQ protease family signature 328 345 4.1E-11 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 PRINTS PR00834 HtrA/DegQ protease family signature 248 268 4.1E-11 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 PRINTS PR00834 HtrA/DegQ protease family signature 287 311 4.1E-11 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 4.1E-11 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 PRINTS PR00834 HtrA/DegQ protease family signature 350 367 4.1E-11 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS20045 564988417345bc5558a56abeecebb29b 397 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 337 348 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CP478_RS20045 564988417345bc5558a56abeecebb29b 397 SUPERFAMILY SSF50494 193 384 7.13E-39 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS05260 c3424542c14aaa6e585620a5974b5fef 266 Gene3D G3DSA:3.40.50.1820 49 257 3.7E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS05260 c3424542c14aaa6e585620a5974b5fef 266 Pfam PF06259 Alpha/beta hydrolase 53 230 2.2E-72 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CP478_RS05260 c3424542c14aaa6e585620a5974b5fef 266 SUPERFAMILY SSF53474 159 205 1.03E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00545 fc41867da6ac2c47672cea2a53782942 183 Pfam PF10862 FcoT-like thioesterase domain 28 178 3.2E-61 T 28-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CP478_RS00545 fc41867da6ac2c47672cea2a53782942 183 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 20 183 1.0E-93 T 28-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 SUPERFAMILY SSF51283 3 149 1.13E-43 T 28-03-2018 IPR029054 dUTPase-like CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 3 150 30.278 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 Gene3D G3DSA:2.70.40.10 1 108 3.7E-43 T 28-03-2018 CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 Pfam PF00692 dUTPase 15 149 9.4E-28 T 28-03-2018 IPR029054 dUTPase-like CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 TIGRFAM TIGR00576 dut: dUTP diphosphatase 5 149 6.6E-49 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CP478_RS14790 43051cc5460143522c361f0a5fd7cbd6 154 Gene3D G3DSA:2.70.40.10 109 149 1.3E-9 T 28-03-2018 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 73 105 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 Gene3D G3DSA:1.10.1740.10 23 129 5.2E-20 T 28-03-2018 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 Gene3D G3DSA:1.10.10.10 130 212 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 SUPERFAMILY SSF88946 25 136 3.53E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 204 8.5E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 Pfam PF08281 Sigma-70, region 4 152 201 2.8E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 SUPERFAMILY SSF88659 134 205 3.18E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS18685 7841728feef0bf393a0cd2cb6cc7e0ae 212 Pfam PF04542 Sigma-70 region 2 49 119 4.4E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 Pfam PF00171 Aldehyde dehydrogenase family 17 490 8.0E-137 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 SUPERFAMILY SSF53720 2 494 2.36E-150 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 Gene3D G3DSA:3.40.605.10 1 265 8.2E-89 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 494 9.2E-188 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CP478_RS04095 169a69333bfb2ed4f688323e7540da10 510 Gene3D G3DSA:3.40.309.10 266 472 3.6E-62 T 28-03-2018 CP478_RS14515 903dedf78c2085aa1c8285fd6ee5d92f 332 SUPERFAMILY SSF56349 76 328 4.71E-43 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS14515 903dedf78c2085aa1c8285fd6ee5d92f 332 Gene3D G3DSA:1.10.443.10 175 332 8.7E-35 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS14515 903dedf78c2085aa1c8285fd6ee5d92f 332 Gene3D G3DSA:1.10.150.130 68 174 1.9E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CP478_RS14515 903dedf78c2085aa1c8285fd6ee5d92f 332 Pfam PF00589 Phage integrase family 186 319 2.6E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS16530 c0301ee6f271fc97cb35dcbc6c6363e8 104 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 49 102 8.0E-16 T 28-03-2018 CP478_RS16530 c0301ee6f271fc97cb35dcbc6c6363e8 104 Pfam PF00934 PE family 3 91 1.3E-19 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS16530 c0301ee6f271fc97cb35dcbc6c6363e8 104 Gene3D G3DSA:1.10.287.1060 1 98 4.2E-4 T 28-03-2018 CP478_RS16530 c0301ee6f271fc97cb35dcbc6c6363e8 104 SUPERFAMILY SSF140459 7 72 1.52E-11 T 28-03-2018 CP478_RS06770 ab35f21b476ad7cd046dfc50a19ef9dc 307 SUPERFAMILY SSF161098 22 296 1.87E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS06770 ab35f21b476ad7cd046dfc50a19ef9dc 307 Gene3D G3DSA:1.10.3720.10 40 300 1.3E-45 T 28-03-2018 CP478_RS06770 ab35f21b476ad7cd046dfc50a19ef9dc 307 Gene3D G3DSA:1.20.58.370 6 39 5.8E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CP478_RS06770 ab35f21b476ad7cd046dfc50a19ef9dc 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 295 7.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 SMART SM00481 98 177 3.0E-21 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 Gene3D G3DSA:1.10.150.110 2 83 8.2E-14 T 28-03-2018 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 Pfam PF02811 PHP domain 99 222 4.4E-10 T 28-03-2018 IPR004013 PHP domain GO:0003824 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 Pfam PF14716 Helix-hairpin-helix domain 5 68 2.6E-13 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 Gene3D G3DSA:3.20.20.140 99 327 1.7E-50 T 28-03-2018 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 PIRSF PIRSF036978 1 335 2.3E-202 T 28-03-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 SUPERFAMILY SSF89550 97 328 1.7E-51 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CP478_RS21080 4dc5a7ed7bc4106cef788fa320c9a1a1 335 SUPERFAMILY SSF47802 3 82 1.7E-13 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CP478_RS14335 160c462f622a8badf8fe8a00fe79e274 166 PIRSF PIRSF010260 2 166 6.0E-72 T 28-03-2018 IPR014457 Uncharacterised conserved protein UCP010260 CP478_RS14335 160c462f622a8badf8fe8a00fe79e274 166 Pfam PF09348 Domain of unknown function (DUF1990) 12 165 4.4E-54 T 28-03-2018 IPR018960 Domain of unknown function DUF1990 CP478_RS06330 18dd76274a6b225778d40ac318a8ec18 213 Gene3D G3DSA:3.30.70.1280 39 122 3.0E-25 T 28-03-2018 CP478_RS06330 18dd76274a6b225778d40ac318a8ec18 213 SUPERFAMILY SSF160379 38 212 2.75E-43 T 28-03-2018 CP478_RS06330 18dd76274a6b225778d40ac318a8ec18 213 PIRSF PIRSF008502 38 213 7.8E-62 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 CP478_RS06330 18dd76274a6b225778d40ac318a8ec18 213 Gene3D G3DSA:3.30.70.1260 131 213 1.1E-17 T 28-03-2018 CP478_RS06330 18dd76274a6b225778d40ac318a8ec18 213 Pfam PF08002 Protein of unknown function (DUF1697) 38 163 1.4E-33 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 SMART SM00044 325 515 7.2E-7 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 Pfam PF00672 HAMP domain 280 325 7.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 SUPERFAMILY SSF158472 279 326 2.88E-5 T 28-03-2018 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 358 527 8.3E-21 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 Gene3D G3DSA:3.30.70.1230 338 531 2.7E-39 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 SUPERFAMILY SSF55073 353 531 4.24E-42 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS07230 142d5e9fd136943e65f392e7be18f16b 541 SMART SM00304 277 329 4.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 SUPERFAMILY SSF75304 2 487 7.06E-153 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 Gene3D G3DSA:3.90.1300.10 2 489 7.3E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 Pfam PF01425 Amidase 25 476 1.9E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 488 89.519 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS16470 e109b8037d1ed32e3d8075d079e03c26 494 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 486 1.0E-188 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Pfam PF00889 Elongation factor TS 67 270 2.7E-63 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Gene3D G3DSA:1.10.8.10 1 55 5.6E-18 T 28-03-2018 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 270 3.4E-73 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Gene3D G3DSA:1.10.286.20 202 221 5.0E-17 T 28-03-2018 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 SUPERFAMILY SSF54713 57 141 8.99E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Gene3D G3DSA:3.30.479.20 56 148 1.1E-19 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Gene3D G3DSA:3.30.479.20 149 201 5.1E-5 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Gene3D G3DSA:3.30.479.20 222 269 3.0E-12 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 SUPERFAMILY SSF54713 142 270 4.19E-35 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 Hamap MF_00050 Elongation factor Ts [tsf]. 1 271 65.756 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CP478_RS15790 1240b89347ddbab354a2cab1a2409249 271 SUPERFAMILY SSF46934 5 55 1.09E-13 T 28-03-2018 IPR009060 UBA-like GO:0005515 CP478_RS00160 7d0c86be9dfc224ecfe16be7a29e515d 101 ProDom PD068262 MB0029 RV0028/MT0030.1 1 101 2.0E-43 T 28-03-2018 IPR024426 Protein of unknown function DUF2694 CP478_RS00160 7d0c86be9dfc224ecfe16be7a29e515d 101 Pfam PF10904 Protein of unknown function (DUF2694) 1 97 3.5E-61 T 28-03-2018 IPR024426 Protein of unknown function DUF2694 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 200 362 3.1E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 27 153 9.6E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 222 6.2E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 251 266 6.2E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Gene3D G3DSA:3.40.50.300 42 183 3.2E-26 T 28-03-2018 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 PIRSF PIRSF006485 25 461 1.3E-158 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Hamap MF_00195 GTPase Der [der]. 26 456 34.178 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Gene3D G3DSA:3.40.50.300 214 373 2.4E-31 T 28-03-2018 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 27 453 5.8E-152 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 SUPERFAMILY SSF52540 161 457 5.61E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 SUPERFAMILY SSF52540 28 188 2.35E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Pfam PF01926 50S ribosome-binding GTPase 29 143 1.3E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Pfam PF01926 50S ribosome-binding GTPase 201 319 3.4E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 375 453 9.7E-25 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Gene3D G3DSA:3.40.50.300 12 41 0.026 T 28-03-2018 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Gene3D G3DSA:3.40.50.300 184 213 0.0034 T 28-03-2018 CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 SMART SM00382 198 341 0.31 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 SMART SM00382 25 171 2.9 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09345 293f8ec5ca0b25edc5bf3a70d1d71968 463 Gene3D G3DSA:3.30.300.20 374 454 3.2E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Hamap MF_01416 ATP synthase subunit delta [atpD]. 267 446 14.207 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 276 443 9.3E-18 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Pfam PF00430 ATP synthase B/B' CF(0) 3 132 1.0E-19 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 135 10.606 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 7 154 6.8E-19 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Pfam PF00213 ATP synthase delta (OSCP) subunit 277 442 4.1E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Gene3D G3DSA:1.20.5.620 59 119 7.5E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Gene3D G3DSA:1.10.520.20 277 380 7.0E-12 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 Gene3D G3DSA:1.10.520.20 179 276 2.3E-4 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 PRINTS PR00125 ATP synthase delta subunit signature 419 437 4.6E-8 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 PRINTS PR00125 ATP synthase delta subunit signature 404 419 4.6E-8 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 PRINTS PR00125 ATP synthase delta subunit signature 271 290 4.6E-8 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07160 b2e506ce65bf53a247a7cb9cac1f1ce8 446 SUPERFAMILY SSF81573 60 118 4.97E-9 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS20705 eaea322d88d359d5aa98bded39862e65 461 Pfam PF01565 FAD binding domain 30 161 1.3E-25 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS20705 eaea322d88d359d5aa98bded39862e65 461 Pfam PF04030 D-arabinono-1,4-lactone oxidase 398 457 5.1E-7 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CP478_RS20705 eaea322d88d359d5aa98bded39862e65 461 SUPERFAMILY SSF56176 12 193 9.35E-37 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS20705 eaea322d88d359d5aa98bded39862e65 461 Gene3D G3DSA:3.30.465.10 75 196 2.8E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS20705 eaea322d88d359d5aa98bded39862e65 461 Gene3D G3DSA:3.30.43.10 4 74 7.8E-5 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 SUPERFAMILY SSF56235 2 235 7.98E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 Pfam PF00733 Asparagine synthase 262 631 8.6E-105 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 SUPERFAMILY SSF52402 253 401 3.72E-81 T 28-03-2018 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 SUPERFAMILY SSF52402 488 627 3.72E-81 T 28-03-2018 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 Gene3D G3DSA:3.40.50.620 241 637 1.1E-78 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 Pfam PF13537 Glutamine amidotransferase domain 59 181 2.9E-38 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 PIRSF PIRSF001589 1 647 1.3E-165 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 568 1.4E-139 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CP478_RS11965 c2dbe9ce6339e6e72baa3c37a8f04e0e 652 Gene3D G3DSA:3.60.20.10 1 240 2.0E-46 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 Pfam PF08281 Sigma-70, region 4 140 191 2.3E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 Gene3D G3DSA:1.10.10.10 96 198 3.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 54 85 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 Gene3D G3DSA:1.10.1740.10 16 95 7.9E-21 T 28-03-2018 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 SUPERFAMILY SSF88946 17 115 2.43E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 SUPERFAMILY SSF88659 139 195 1.68E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 193 5.6E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 Pfam PF04542 Sigma-70 region 2 37 99 1.4E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS17675 4a3801b8966fdf061fdc08d3aa914ca7 216 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 19 207 1.9E-106 T 28-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 Gene3D G3DSA:3.40.50.300 948 1118 6.7E-30 T 28-03-2018 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 Pfam PF13087 AAA domain 933 1110 1.4E-23 T 28-03-2018 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 Gene3D G3DSA:3.40.50.300 744 947 7.4E-24 T 28-03-2018 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 Pfam PF13482 RNase_H superfamily 312 501 1.8E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 55 501 2.5E-47 T 28-03-2018 IPR019993 RecB family nuclease, TM0106, putative CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 Pfam PF13604 AAA domain 756 910 6.4E-13 T 28-03-2018 CP478_RS06850 e15482fb2f04d26bbc605e7fcfc5772c 1139 SUPERFAMILY SSF52540 753 1116 1.79E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 Gene3D G3DSA:3.40.47.10 1 208 6.2E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 219 351 1.2E-16 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 SUPERFAMILY SSF53901 3 352 1.12E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 Gene3D G3DSA:3.40.47.10 209 353 3.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 9 197 1.3E-21 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CP478_RS09105 acdfb3dba9569cd1a7e024feb113f9c7 353 PIRSF PIRSF000451 1 353 1.5E-116 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CP478_RS16490 1ece9daead39fa1e25dcd9726d87f7ae 337 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 4 328 4.3E-89 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CP478_RS16490 1ece9daead39fa1e25dcd9726d87f7ae 337 Gene3D G3DSA:3.20.20.210 52 337 2.2E-45 T 28-03-2018 CP478_RS16490 1ece9daead39fa1e25dcd9726d87f7ae 337 SUPERFAMILY SSF51726 7 332 6.28E-32 T 28-03-2018 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 Pfam PF00248 Aldo/keto reductase family 30 265 1.3E-41 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 Gene3D G3DSA:3.20.20.100 7 282 4.0E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 SUPERFAMILY SSF51430 13 274 1.09E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PRINTS PR00069 Aldo-keto reductase signature 165 194 1.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PRINTS PR00069 Aldo-keto reductase signature 131 148 1.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PRINTS PR00069 Aldo-keto reductase signature 202 226 1.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PIRSF PIRSF000097 7 123 6.9E-35 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS16245 4bf39a5b30ac24b5bc5f9f327698b045 282 PIRSF PIRSF000097 121 280 1.3E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 9 627 1.4E-236 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 Pfam PF00361 Proton-conducting membrane transporter 140 427 3.3E-82 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 117 137 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 89 114 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 250 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 164 185 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 251 277 1.2E-62 T 28-03-2018 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 128 1.9E-23 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 269 291 6.0E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 425 447 6.0E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 65 89 6.0E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CP478_RS17280 12ced5c69a4262e4646e597f4232ac3e 633 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 91 111 6.0E-13 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CP478_RS15310 26a5be585f526b5a34c70bdfab3580c4 562 Gene3D G3DSA:1.20.5.400 187 274 0.024 T 28-03-2018 CP478_RS15310 26a5be585f526b5a34c70bdfab3580c4 562 SUPERFAMILY SSF53474 286 457 3.87E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15310 26a5be585f526b5a34c70bdfab3580c4 562 Pfam PF06259 Alpha/beta hydrolase 277 466 2.7E-77 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CP478_RS15310 26a5be585f526b5a34c70bdfab3580c4 562 Gene3D G3DSA:1.20.120.330 14 165 0.0097 T 28-03-2018 CP478_RS15310 26a5be585f526b5a34c70bdfab3580c4 562 Gene3D G3DSA:3.40.50.1820 279 520 1.6E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PIRSF PIRSF000114 1 334 2.1E-97 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 325 36.49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 137 157 9.6E-49 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 162 5.8E-51 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 SUPERFAMILY SSF48179 184 334 2.38E-49 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 Gene3D G3DSA:1.10.1040.10 184 333 3.1E-50 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 Gene3D G3DSA:3.40.50.720 5 183 1.0E-41 T 28-03-2018 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 323 5.1E-49 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CP478_RS16305 901bde8cb6e179ed7eaf314dcea21fd9 334 SUPERFAMILY SSF51735 8 182 1.42E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 PIRSF PIRSF026673 12 481 6.2E-158 T 28-03-2018 IPR016846 Predicted ion channel, cNMP-binding CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 Gene3D G3DSA:2.30.30.60 175 225 2.4E-8 T 28-03-2018 CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 Gene3D G3DSA:2.60.120.10 329 465 6.3E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 SMART SM00100 334 451 6.9E-19 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 SUPERFAMILY SSF51206 338 461 4.01E-19 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 Pfam PF00027 Cyclic nucleotide-binding domain 353 438 4.6E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 SUPERFAMILY SSF50182 160 224 4.9E-11 T 28-03-2018 IPR010920 LSM domain CP478_RS13295 805e084047ca89f6d307edc49ce6f9e0 481 Pfam PF00924 Mechanosensitive ion channel 117 310 8.8E-41 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CP478_RS10995 7ef359276d2bd3168b96c4ceb61fe2cb 418 Pfam PF01844 HNH endonuclease 314 352 2.9E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CP478_RS10995 7ef359276d2bd3168b96c4ceb61fe2cb 418 SMART SM00507 297 348 2.5E-13 T 28-03-2018 IPR003615 HNH nuclease CP478_RS10995 7ef359276d2bd3168b96c4ceb61fe2cb 418 Pfam PF02720 Domain of unknown function (DUF222) 22 306 2.0E-73 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS10995 7ef359276d2bd3168b96c4ceb61fe2cb 418 Gene3D G3DSA:3.40.1800.10 288 355 3.0E-10 T 28-03-2018 CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 SMART SM00893 24 219 5.1E-49 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 SUPERFAMILY SSF52402 3 260 1.19E-64 T 28-03-2018 CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 PIRSF PIRSF000090 2 266 8.7E-82 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 163 183 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 Gene3D G3DSA:3.40.50.620 2 266 1.5E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS16570 b53077dc8a9044cbce1b5311baec5976 266 Pfam PF01012 Electron transfer flavoprotein domain 25 214 6.8E-41 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CP478_RS12420 cd90b4d752819ead7b4cbb764eac6573 230 Pfam PF01323 DSBA-like thioredoxin domain 3 156 2.7E-13 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CP478_RS12420 cd90b4d752819ead7b4cbb764eac6573 230 Gene3D G3DSA:3.40.30.10 2 60 8.6E-9 T 28-03-2018 CP478_RS12420 cd90b4d752819ead7b4cbb764eac6573 230 SUPERFAMILY SSF52833 3 158 1.34E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS12420 cd90b4d752819ead7b4cbb764eac6573 230 Gene3D G3DSA:3.40.30.10 61 161 1.8E-13 T 28-03-2018 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 SUPERFAMILY SSF47203 236 389 3.14E-58 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 125 8.4E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 387 1.2E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 PIRSF PIRSF016578 134 388 2.6E-16 T 28-03-2018 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 PIRSF PIRSF016578 11 109 1.5E-8 T 28-03-2018 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 133 145 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Gene3D G3DSA:2.40.110.10 130 227 4.0E-40 T 28-03-2018 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Gene3D G3DSA:1.10.540.10 4 126 1.5E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Gene3D G3DSA:1.20.140.10 228 389 4.1E-63 T 28-03-2018 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 226 6.9E-30 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS17950 5e90fdac1563f5a22a72dfc650eba356 389 SUPERFAMILY SSF56645 13 250 2.62E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 Pfam PF00501 AMP-binding enzyme 8 470 8.0E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 SUPERFAMILY SSF56801 3 575 1.11E-83 T 28-03-2018 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 Gene3D G3DSA:3.30.300.30 465 574 4.5E-12 T 28-03-2018 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 Gene3D G3DSA:3.40.50.980 1 173 2.6E-23 T 28-03-2018 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 Gene3D G3DSA:3.40.50.980 174 350 6.3E-27 T 28-03-2018 CP478_RS02155 9224cad1142ec9ca9462ab2a2bd90bb1 585 Gene3D G3DSA:2.30.38.10 386 464 3.3E-14 T 28-03-2018 CP478_RS17380 ca39eb913c378d83b6c8ac9088fa74bf 318 Pfam PF12697 Alpha/beta hydrolase family 52 309 8.9E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17380 ca39eb913c378d83b6c8ac9088fa74bf 318 Gene3D G3DSA:3.40.50.1820 31 317 3.1E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17380 ca39eb913c378d83b6c8ac9088fa74bf 318 SUPERFAMILY SSF53474 52 312 8.87E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11110 a3cf3fa1710178eac71421e4bf03a3fc 213 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 15 193 7.0E-39 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS11110 a3cf3fa1710178eac71421e4bf03a3fc 213 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 55 1.0E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS11110 a3cf3fa1710178eac71421e4bf03a3fc 213 SUPERFAMILY SSF109854 11 132 7.69E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS11110 a3cf3fa1710178eac71421e4bf03a3fc 213 Gene3D G3DSA:1.20.120.450 1 192 1.5E-21 T 28-03-2018 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 PIRSF PIRSF000484 1 448 6.7E-144 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 9 434 6.4E-175 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 SUPERFAMILY SSF51690 139 440 1.0E-95 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 330 1.2E-11 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 SUPERFAMILY SSF54675 8 136 1.45E-44 T 28-03-2018 CP478_RS03070 6472abfe8891710a09372e560e3b1f07 463 Gene3D G3DSA:3.20.140.10 3 363 1.7E-108 T 28-03-2018 CP478_RS14895 c9bbc85207969500b2dea53f3400b092 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 78.229 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CP478_RS14895 c9bbc85207969500b2dea53f3400b092 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 9.4E-48 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CP478_RS14895 c9bbc85207969500b2dea53f3400b092 154 Pfam PF03477 ATP cone domain 47 131 6.6E-14 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CP478_RS05405 1eb4beea03e326ebbe5148e869794208 218 Pfam PF08666 SAF domain 55 111 6.6E-10 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CP478_RS05405 1eb4beea03e326ebbe5148e869794208 218 Gene3D G3DSA:3.90.1210.10 52 117 3.2E-15 T 28-03-2018 CP478_RS05405 1eb4beea03e326ebbe5148e869794208 218 SMART SM00858 54 116 1.6E-10 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 20 136 6.7E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 SUPERFAMILY SSF53137 24 139 4.11E-49 T 28-03-2018 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 107 129 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 14 139 33.549 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 Pfam PF00411 Ribosomal protein S11 29 138 1.3E-48 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 PIRSF PIRSF002131 8 139 7.1E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CP478_RS18930 c789fc2b555e5bfbb441497d679a7708 139 Gene3D G3DSA:3.30.420.80 13 139 2.0E-45 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CP478_RS07610 678d4d8e0f377942e172587d6338b4ed 105 Gene3D G3DSA:1.10.8.50 48 104 2.9E-5 T 28-03-2018 CP478_RS07610 678d4d8e0f377942e172587d6338b4ed 105 SUPERFAMILY SSF46946 53 102 2.59E-5 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CP478_RS07610 678d4d8e0f377942e172587d6338b4ed 105 PIRSF PIRSF002134 37 104 0.0023 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 PRINTS PR00163 Rubredoxin signature 3 19 4.6E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 PRINTS PR00163 Rubredoxin signature 33 49 4.6E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 SUPERFAMILY SSF57802 1 52 6.52E-18 T 28-03-2018 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 Pfam PF00301 Rubredoxin 4 50 3.2E-21 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CP478_RS17825 0b1fbaf4a885ce23993d91c89a0988ad 55 Gene3D G3DSA:2.20.28.10 1 54 1.7E-21 T 28-03-2018 CP478_RS00770 4803612beeb13732f477c3f7e35fa82f 308 Gene3D G3DSA:1.10.340.30 98 261 4.9E-20 T 28-03-2018 CP478_RS00770 4803612beeb13732f477c3f7e35fa82f 308 SUPERFAMILY SSF48150 109 287 8.03E-29 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS09465 8f09218187296923ed8c3fbb1fea7383 178 Pfam PF03595 Voltage-dependent anion channel 2 130 3.6E-14 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 Pfam PF03477 ATP cone domain 8 92 1.9E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 SUPERFAMILY SSF48168 12 186 2.12E-10 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 114 665 7.2E-213 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 108 188 2.0E-19 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 SUPERFAMILY SSF51998 190 559 8.24E-146 T 28-03-2018 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 SUPERFAMILY SSF51998 591 666 8.24E-146 T 28-03-2018 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 Pfam PF02867 Ribonucleotide reductase, barrel domain 192 655 3.0E-142 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 Gene3D G3DSA:3.20.70.20 90 662 2.7E-178 T 28-03-2018 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 266 285 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 442 464 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 404 427 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 371 382 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 509 536 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03050 82d47fe8180dd347eeb0abf016d4a709 692 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 493 5.4E-36 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Gene3D G3DSA:1.10.287.1060 498 605 0.12 T 28-03-2018 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Pfam PF03176 MMPL family 676 1018 1.3E-96 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Pfam PF03176 MMPL family 57 382 8.8E-99 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 SUPERFAMILY SSF82866 134 358 2.35E-26 T 28-03-2018 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Gene3D G3DSA:1.20.120.570 626 731 7.5E-5 T 28-03-2018 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Gene3D G3DSA:1.20.1640.10 763 986 4.9E-22 T 28-03-2018 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 Gene3D G3DSA:1.20.1640.10 149 366 1.6E-28 T 28-03-2018 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 TIGRFAM TIGR00833 actII: transport protein 22 988 0.0 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS08350 fc233c11947d229d91f84b151e1c3971 1146 SUPERFAMILY SSF82866 775 988 6.54E-24 T 28-03-2018 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 SUPERFAMILY SSF53901 9 232 5.07E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 SUPERFAMILY SSF53901 283 391 4.85E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 PIRSF PIRSF000429 3 402 1.7E-35 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 Pfam PF00108 Thiolase, N-terminal domain 9 227 5.4E-9 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 Gene3D G3DSA:3.40.47.10 1 221 2.1E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS08900 e506a259062c72e17341364c8cbcdeed 402 Gene3D G3DSA:3.40.47.10 222 398 5.2E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS14670 e0f4e78bd8fa21c56a72fc3dc7b23f59 250 Gene3D G3DSA:3.40.50.150 3 226 5.2E-29 T 28-03-2018 CP478_RS14670 e0f4e78bd8fa21c56a72fc3dc7b23f59 250 SUPERFAMILY SSF53335 6 196 2.76E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14670 e0f4e78bd8fa21c56a72fc3dc7b23f59 250 Pfam PF13649 Methyltransferase domain 54 149 4.0E-15 T 28-03-2018 CP478_RS20910 a1c0830eaaefb55ed958a000873a4852 203 Pfam PF00239 Resolvase, N terminal domain 63 188 1.3E-9 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS20910 a1c0830eaaefb55ed958a000873a4852 203 SUPERFAMILY SSF53041 61 192 2.22E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS20910 a1c0830eaaefb55ed958a000873a4852 203 Gene3D G3DSA:1.10.1660.20 11 55 3.4E-4 T 28-03-2018 CP478_RS20910 a1c0830eaaefb55ed958a000873a4852 203 Gene3D G3DSA:3.40.50.1390 57 200 2.2E-14 T 28-03-2018 CP478_RS20910 a1c0830eaaefb55ed958a000873a4852 203 SMART SM00857 62 190 4.9E-7 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 17 180 3.4E-48 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PIRSF PIRSF001467 6 182 3.5E-61 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 SUPERFAMILY SSF50891 16 181 2.78E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 66 83 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 30 45 3.3E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 139 154 3.3E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 111 126 3.3E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 71 83 3.3E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 126 138 3.3E-26 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CP478_RS00060 4ebc200723a8ea71aecd0a7b82e60248 182 Gene3D G3DSA:2.40.100.10 2 182 1.3E-65 T 28-03-2018 IPR029000 Cyclophilin-like domain CP478_RS18430 c41981e456540ff7fb8b9e26db97b0cb 876 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 523 633 1.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS18430 c41981e456540ff7fb8b9e26db97b0cb 876 SUPERFAMILY SSF55874 509 633 2.75E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS18430 c41981e456540ff7fb8b9e26db97b0cb 876 Gene3D G3DSA:3.30.565.10 440 633 3.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS18430 c41981e456540ff7fb8b9e26db97b0cb 876 SMART SM00304 341 407 0.0021 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS18430 c41981e456540ff7fb8b9e26db97b0cb 876 SMART SM00387 519 634 3.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS06420 799341435ce1067e7864422c3b501ebc 100 Pfam PF00934 PE family 2 92 4.0E-22 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06420 799341435ce1067e7864422c3b501ebc 100 SUPERFAMILY SSF140459 8 83 6.28E-18 T 28-03-2018 CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 SUPERFAMILY SSF51735 2 270 9.51E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 141 0.0074 T 28-03-2018 CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 Pfam PF00106 short chain dehydrogenase 5 140 4.4E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01630 56e905c4b211e3b9014150620d9c979a 302 Gene3D G3DSA:3.40.50.720 1 302 4.1E-48 T 28-03-2018 CP478_RS14295 52588fd2a2b1e970544c0fc9213f3e75 351 SUPERFAMILY SSF55811 174 310 6.77E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS14295 52588fd2a2b1e970544c0fc9213f3e75 351 Pfam PF00293 NUDIX domain 177 318 4.3E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS14295 52588fd2a2b1e970544c0fc9213f3e75 351 ProSitePatterns PS00893 Nudix box signature. 219 240 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS14295 52588fd2a2b1e970544c0fc9213f3e75 351 Gene3D G3DSA:3.90.79.10 171 335 1.7E-19 T 28-03-2018 CP478_RS14295 52588fd2a2b1e970544c0fc9213f3e75 351 Gene3D G3DSA:1.20.1440.20 17 169 1.4E-31 T 28-03-2018 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 27 466 5.9E-141 T 28-03-2018 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 Gene3D G3DSA:3.80.30.20 165 406 1.3E-52 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 Pfam PF00919 Uncharacterized protein family UPF0004 27 125 1.6E-28 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 Pfam PF04055 Radical SAM superfamily 172 349 1.9E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 25 471 69.295 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 SMART SM00729 168 392 1.9E-57 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 172 192 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 SUPERFAMILY SSF102114 156 400 2.22E-58 T 28-03-2018 CP478_RS14970 6a9a5bba4b6050aa7dc6d6a9a6787886 512 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 26 467 8.1E-156 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CP478_RS12830 74e45f205a8f42f61536706def0c40a1 391 Pfam PF00823 PPE family 7 164 4.1E-60 T 28-03-2018 IPR000030 PPE family CP478_RS12830 74e45f205a8f42f61536706def0c40a1 391 SUPERFAMILY SSF140459 4 175 2.62E-61 T 28-03-2018 CP478_RS12830 74e45f205a8f42f61536706def0c40a1 391 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 299 387 6.6E-11 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS12830 74e45f205a8f42f61536706def0c40a1 391 Gene3D G3DSA:1.10.287.1060 26 112 5.2E-6 T 28-03-2018 CP478_RS20280 c5885ebb653e8478c50d733c6a776f9d 413 Pfam PF08245 Mur ligase middle domain 56 264 4.7E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS20280 c5885ebb653e8478c50d733c6a776f9d 413 SUPERFAMILY SSF53623 225 278 3.27E-33 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS20280 c5885ebb653e8478c50d733c6a776f9d 413 SUPERFAMILY SSF53623 49 191 3.27E-33 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS20280 c5885ebb653e8478c50d733c6a776f9d 413 Pfam PF08353 Domain of unknown function (DUF1727) 303 402 4.1E-24 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CP478_RS20280 c5885ebb653e8478c50d733c6a776f9d 413 Gene3D G3DSA:3.40.1190.10 46 285 7.1E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS15465 6be60634d686cdabca342f0c7196fe60 181 PIRSF PIRSF018957 1 181 1.2E-95 T 28-03-2018 IPR008307 Uncharacterised conserved protein UCP018957 CP478_RS15465 6be60634d686cdabca342f0c7196fe60 181 Pfam PF08819 Domain of unknown function (DUF1802) 4 174 1.7E-60 T 28-03-2018 IPR014923 Protein of unknown function DUF1802 CP478_RS09010 ff6aa0d4bbd03a5524f86a75573785d1 310 Pfam PF00934 PE family 1 93 5.4E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09010 ff6aa0d4bbd03a5524f86a75573785d1 310 Gene3D G3DSA:1.10.287.1060 1 98 7.5E-4 T 28-03-2018 CP478_RS09010 ff6aa0d4bbd03a5524f86a75573785d1 310 SUPERFAMILY SSF140459 8 84 1.33E-20 T 28-03-2018 CP478_RS01470 f329553b3240fdcb36e194f416c9bdfd 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 3.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01470 f329553b3240fdcb36e194f416c9bdfd 206 SUPERFAMILY SSF48498 80 200 6.67E-30 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01470 f329553b3240fdcb36e194f416c9bdfd 206 Gene3D G3DSA:1.10.357.10 59 206 4.4E-11 T 28-03-2018 CP478_RS01470 f329553b3240fdcb36e194f416c9bdfd 206 Gene3D G3DSA:1.10.10.60 3 58 9.8E-14 T 28-03-2018 CP478_RS01470 f329553b3240fdcb36e194f416c9bdfd 206 SUPERFAMILY SSF46689 5 81 3.75E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS11470 f6a4fb0aaf6659f3c99bb53c96ef18ac 98 Pfam PF00934 PE family 1 92 8.5E-28 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS11470 f6a4fb0aaf6659f3c99bb53c96ef18ac 98 SUPERFAMILY SSF140459 8 84 7.85E-21 T 28-03-2018 CP478_RS04070 56d8a8896b0f69be494ebd4da67dc603 142 SUPERFAMILY SSF88723 1 138 3.64E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS04070 56d8a8896b0f69be494ebd4da67dc603 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 17.766 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS04070 56d8a8896b0f69be494ebd4da67dc603 142 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 141 2.9E-51 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS04070 56d8a8896b0f69be494ebd4da67dc603 142 Pfam PF01850 PIN domain 3 133 7.0E-13 T 28-03-2018 IPR002716 PIN domain CP478_RS04070 56d8a8896b0f69be494ebd4da67dc603 142 Gene3D G3DSA:3.40.50.1010 1 142 7.6E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 Gene3D G3DSA:3.40.50.720 47 258 3.8E-56 T 28-03-2018 CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 Gene3D G3DSA:3.40.50.720 3 46 1.0E-10 T 28-03-2018 CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 SUPERFAMILY SSF51735 5 253 1.84E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 252 2.9E-56 T 28-03-2018 CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05060 131ee753c05721a60cf8760028b8053d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.9E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19975 3475bcdc90dfdeec7c0f71a5652ff561 350 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 2 338 4.8E-115 T 28-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like CP478_RS19975 3475bcdc90dfdeec7c0f71a5652ff561 350 Gene3D G3DSA:3.40.50.300 115 341 3.0E-25 T 28-03-2018 CP478_RS19975 3475bcdc90dfdeec7c0f71a5652ff561 350 SUPERFAMILY SSF52540 117 318 1.28E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 267 6.4E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 511 537 1.1E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Pfam PF00005 ABC transporter 308 459 5.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Pfam PF00005 ABC transporter 27 182 1.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 SMART SM00382 316 509 4.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 SMART SM00382 34 231 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 SUPERFAMILY SSF52540 8 253 6.29E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 SUPERFAMILY SSF52540 282 531 5.23E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Gene3D G3DSA:3.40.50.300 280 545 2.6E-68 T 28-03-2018 CP478_RS20000 9e9974a473a81666ef908515cb65502d 548 Gene3D G3DSA:3.40.50.300 5 279 2.2E-67 T 28-03-2018 CP478_RS21340 163a53fcc9d3dcbf0b31e0559ddc6ed5 169 Gene3D G3DSA:4.10.1080.10 7 68 0.013 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CP478_RS21340 163a53fcc9d3dcbf0b31e0559ddc6ed5 169 Gene3D G3DSA:4.10.1080.10 95 168 1.3E-6 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CP478_RS21340 163a53fcc9d3dcbf0b31e0559ddc6ed5 169 SUPERFAMILY SSF103647 101 165 1.96E-10 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CP478_RS21340 163a53fcc9d3dcbf0b31e0559ddc6ed5 169 SUPERFAMILY SSF103647 18 70 5.36E-5 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 465 2.0E-180 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 SUPERFAMILY SSF53448 9 318 2.7E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Gene3D G3DSA:2.160.10.10 252 360 7.9E-23 T 28-03-2018 CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Pfam PF12804 MobA-like NTP transferase domain 9 143 4.3E-20 T 28-03-2018 IPR025877 MobA-like NTP transferase CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Gene3D G3DSA:2.160.10.10 361 487 9.5E-20 T 28-03-2018 CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 463 39.289 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Gene3D G3DSA:3.90.550.10 3 251 8.6E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 328 362 4.6E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 277 311 3.4E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 406 439 5.9E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CP478_RS05570 97de6265a8fb21d46d6233ae83740f54 495 SUPERFAMILY SSF51161 261 454 1.07E-41 T 28-03-2018 IPR011004 Trimeric LpxA-like CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 SUPERFAMILY SSF158472 279 327 1.7E-6 T 28-03-2018 CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 Gene3D G3DSA:3.30.70.1230 339 533 8.3E-37 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 SUPERFAMILY SSF55073 354 532 4.87E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 359 526 2.1E-20 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 Pfam PF00672 HAMP domain 279 326 1.4E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 SMART SM00304 278 330 1.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS19895 833036bc2589fd9d8767d6218eb21f98 549 SMART SM00044 326 523 1.8E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 Gene3D G3DSA:3.30.930.10 1 217 1.1E-62 T 28-03-2018 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 32 264 5.8E-39 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 Pfam PF02237 Biotin protein ligase C terminal domain 218 264 3.0E-12 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 SUPERFAMILY SSF55681 27 211 3.81E-42 T 28-03-2018 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 Pfam PF03099 Biotin/lipoate A/B protein ligase family 57 147 1.4E-4 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CP478_RS17975 9d43e2a0bac87f24f17ce2a4e1412b46 266 Gene3D G3DSA:2.30.30.100 218 266 7.2E-17 T 28-03-2018 CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Gene3D G3DSA:3.10.350.10 53 103 2.4E-9 T 28-03-2018 CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Gene3D G3DSA:3.10.350.10 104 152 1.5E-11 T 28-03-2018 CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 SUPERFAMILY SSF53474 172 426 4.7E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Pfam PF00756 Putative esterase 182 443 1.7E-67 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Pfam PF01476 LysM domain 56 102 1.3E-7 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Pfam PF01476 LysM domain 107 152 1.1E-9 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Pfam PF01476 LysM domain 6 51 2.8E-5 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Gene3D G3DSA:3.10.350.10 1 52 5.0E-8 T 28-03-2018 CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 SUPERFAMILY SSF54106 105 152 3.27E-5 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 Gene3D G3DSA:3.40.50.1820 161 455 1.3E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 SMART SM00257 4 51 9.4E-7 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 SMART SM00257 106 153 3.9E-10 T 28-03-2018 IPR018392 LysM domain CP478_RS07040 1b854f4e6141ccbf1f07df2d03737454 456 SMART SM00257 55 102 5.3E-7 T 28-03-2018 IPR018392 LysM domain CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Gene3D G3DSA:3.40.50.2300 121 260 0.0026 T 28-03-2018 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 SUPERFAMILY SSF55904 720 767 2.88E-15 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 SUPERFAMILY SSF55904 792 892 2.88E-15 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Gene3D G3DSA:3.90.1150.10 629 782 2.0E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Gene3D G3DSA:3.40.640.10 290 628 9.9E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 290 515 1.9E-49 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 556 747 3.3E-23 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Gene3D G3DSA:3.90.100.10 783 916 3.2E-24 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 SUPERFAMILY SSF53383 290 512 1.26E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 SUPERFAMILY SSF53383 551 762 1.26E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS13875 caaab26f2a1d82cbb832cc75e872dd0b 947 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 825 880 2.1E-4 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 Pfam PF00561 alpha/beta hydrolase fold 34 281 1.3E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 236 252 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 118 131 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 269 291 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 40 58 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 60 75 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 PRINTS PR00412 Epoxide hydrolase signature 104 117 4.5E-20 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 Gene3D G3DSA:3.40.50.1820 3 297 3.0E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00730 70ce8bf2ad651b21010e871374602b13 300 SUPERFAMILY SSF53474 7 293 1.06E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01780 8b1c36c4c8e0d42c1b07fefd4bb47a8d 124 Pfam PF12680 SnoaL-like domain 9 104 1.3E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS01780 8b1c36c4c8e0d42c1b07fefd4bb47a8d 124 SUPERFAMILY SSF54427 1 114 1.16E-11 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS01780 8b1c36c4c8e0d42c1b07fefd4bb47a8d 124 Gene3D G3DSA:3.10.450.50 1 122 3.8E-9 T 28-03-2018 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 SMART SM01130 11 297 9.0E-111 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 2.7E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 2.7E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 2.7E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 2.7E-29 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 Pfam PF00701 Dihydrodipicolinate synthetase family 13 295 5.4E-77 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 Gene3D G3DSA:3.20.20.70 6 300 1.5E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 290 2.7E-76 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 295 54.846 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 SUPERFAMILY SSF51569 12 298 9.42E-91 T 28-03-2018 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 PIRSF PIRSF001365 9 299 2.5E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CP478_RS15085 ae318e214e5940b18587017c7019d012 300 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS18460 4d6e9052dafd8228f17c446b9ed4cafe 446 SUPERFAMILY SSF52777 69 174 5.89E-6 T 28-03-2018 CP478_RS18460 4d6e9052dafd8228f17c446b9ed4cafe 446 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 408 1.2E-110 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS18460 4d6e9052dafd8228f17c446b9ed4cafe 446 Pfam PF06974 Protein of unknown function (DUF1298) 271 399 3.1E-13 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS18460 4d6e9052dafd8228f17c446b9ed4cafe 446 Gene3D G3DSA:3.30.559.10 3 183 1.8E-5 T 28-03-2018 CP478_RS18460 4d6e9052dafd8228f17c446b9ed4cafe 446 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 237 1.2E-40 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 Pfam PF12849 PBP superfamily domain 46 336 6.7E-48 T 28-03-2018 IPR024370 PBP domain CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 PIRSF PIRSF002756 5 370 2.7E-104 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 SUPERFAMILY SSF53850 49 370 9.53E-78 T 28-03-2018 CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 Gene3D G3DSA:3.40.190.10 49 221 4.3E-29 T 28-03-2018 CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 Gene3D G3DSA:3.40.190.10 225 370 3.3E-14 T 28-03-2018 CP478_RS05085 202af9fa371b7b9979b9fbae091af3d6 370 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 50 369 1.6E-99 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS00555 2a2a9da6febf4a4d0238355549cda6e3 78 Gene3D G3DSA:1.10.1200.10 1 76 1.6E-6 T 28-03-2018 CP478_RS00555 2a2a9da6febf4a4d0238355549cda6e3 78 Pfam PF00550 Phosphopantetheine attachment site 3 68 5.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00555 2a2a9da6febf4a4d0238355549cda6e3 78 SUPERFAMILY SSF47336 2 70 1.3E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.0E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 2.7E-5 T 28-03-2018 CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 SUPERFAMILY SSF51735 1 258 8.7E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 Gene3D G3DSA:3.40.50.720 1 287 9.5E-58 T 28-03-2018 CP478_RS11580 49b069a71f1f765ef65984f8233519cd 293 Pfam PF00106 short chain dehydrogenase 7 196 2.4E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 Gene3D G3DSA:3.40.50.1100 117 340 1.1E-51 T 28-03-2018 CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 57 70 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 336 428 2.7E-29 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 Gene3D G3DSA:3.40.50.1100 65 116 3.4E-20 T 28-03-2018 CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 TIGRFAM TIGR02079 THD1: threonine dehydratase 21 429 8.0E-200 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 323 3.9E-76 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS08540 727eef849f2356e8f0b35b9d7d7ab21f 429 SUPERFAMILY SSF53686 20 373 3.8E-92 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 PIRSF PIRSF005384 4 152 5.5E-49 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 Gene3D G3DSA:3.40.1400.10 3 155 3.9E-54 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 Pfam PF02502 Ribose/Galactose Isomerase 6 143 5.5E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 SUPERFAMILY SSF89623 4 155 2.22E-52 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 4 151 2.6E-65 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CP478_RS13475 0a825c4d531c41ecdcfa95cc1b3b3e00 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 6 150 2.9E-59 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CP478_RS07120 2b143115d5361412672014b74394a488 357 Gene3D G3DSA:1.20.58.410 3 97 1.9E-18 T 28-03-2018 CP478_RS07120 2b143115d5361412672014b74394a488 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 357 35.064 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CP478_RS07120 2b143115d5361412672014b74394a488 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CP478_RS07120 2b143115d5361412672014b74394a488 357 Gene3D G3DSA:3.30.160.20 211 292 5.3E-31 T 28-03-2018 CP478_RS07120 2b143115d5361412672014b74394a488 357 Pfam PF00472 RF-1 domain 215 322 5.7E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CP478_RS07120 2b143115d5361412672014b74394a488 357 SUPERFAMILY SSF75620 11 354 6.28E-120 T 28-03-2018 CP478_RS07120 2b143115d5361412672014b74394a488 357 SMART SM00937 66 179 2.5E-43 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CP478_RS07120 2b143115d5361412672014b74394a488 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 355 1.9E-149 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CP478_RS07120 2b143115d5361412672014b74394a488 357 Pfam PF03462 PCRF domain 13 204 1.0E-60 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CP478_RS12890 3d8cbe31fa4b3d383524de330c6baf56 484 Gene3D G3DSA:3.90.1300.10 19 484 2.2E-121 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS12890 3d8cbe31fa4b3d383524de330c6baf56 484 Pfam PF01425 Amidase 39 460 1.6E-120 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS12890 3d8cbe31fa4b3d383524de330c6baf56 484 SUPERFAMILY SSF75304 22 478 2.09E-112 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS12890 3d8cbe31fa4b3d383524de330c6baf56 484 ProSitePatterns PS00571 Amidases signature. 165 196 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CP478_RS21235 16ba7eb13e04134e135d03f37349b05a 537 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 173 262 2.1E-18 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS21235 16ba7eb13e04134e135d03f37349b05a 537 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 11 337 3.1E-80 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS13015 ff768b427a4b8d7138dadbfc2eaeb8de 417 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 16 402 4.7E-110 T 28-03-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily CP478_RS02530 b301ff96dae4a3a3cf777258c1fc3dbe 140 Pfam PF01381 Helix-turn-helix 26 79 1.2E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS02530 b301ff96dae4a3a3cf777258c1fc3dbe 140 SMART SM00530 25 80 2.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CP478_RS02530 b301ff96dae4a3a3cf777258c1fc3dbe 140 SUPERFAMILY SSF47413 19 82 6.76E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CP478_RS02530 b301ff96dae4a3a3cf777258c1fc3dbe 140 Gene3D G3DSA:1.10.260.40 19 86 7.2E-19 T 28-03-2018 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 SMART SM00882 5 234 3.0E-88 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 Gene3D G3DSA:3.40.1080.10 1 248 9.0E-103 T 28-03-2018 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 Pfam PF01144 Coenzyme A transferase 6 233 1.2E-78 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 235 1.1E-69 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CP478_RS13690 8dde291cdcbd383a17ecc3bcf8e1d6d1 248 SUPERFAMILY SSF100950 1 245 2.67E-89 T 28-03-2018 CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 SUPERFAMILY SSF46689 33 140 4.48E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 Gene3D G3DSA:2.30.30.130 352 398 3.6E-4 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 Pfam PF09299 Mu transposase, C-terminal 341 388 3.6E-10 T 28-03-2018 IPR015378 Transposase-like, Mu, C-terminal CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 Gene3D G3DSA:3.30.420.10 151 351 6.0E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 Pfam PF00665 Integrase core domain 159 272 5.6E-27 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 Pfam PF13518 Helix-turn-helix domain 38 86 1.5E-9 T 28-03-2018 CP478_RS15390 4ca89c3bdb5ef0ac0efebbe879afe335 469 SUPERFAMILY SSF53098 155 321 9.11E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS18270 502e552e36f2c5820ae2908423a01295 289 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 21 289 2.2E-121 T 28-03-2018 IPR005274 Inner membrane protein YhjD CP478_RS18270 502e552e36f2c5820ae2908423a01295 289 Pfam PF03631 Virulence factor BrkB 32 287 1.0E-39 T 28-03-2018 IPR017039 Virulence factor BrkB CP478_RS18270 502e552e36f2c5820ae2908423a01295 289 PIRSF PIRSF035875 14 286 7.7E-20 T 28-03-2018 IPR017039 Virulence factor BrkB CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 SUPERFAMILY SSF50129 7 186 4.09E-46 T 28-03-2018 IPR011032 GroES-like CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 149 1.6E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 Gene3D G3DSA:3.40.50.720 179 316 2.1E-10 T 28-03-2018 CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 SUPERFAMILY SSF51735 156 314 3.13E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 72 86 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 12 345 1.8E-203 T 28-03-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CP478_RS10120 b52dde96444ba869e92be38f2c296398 346 Gene3D G3DSA:3.90.180.10 6 178 5.6E-49 T 28-03-2018 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 163 318 3.4E-69 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 SMART SM00846 3 158 2.4E-82 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 235 252 2.9E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 2.9E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 275 290 2.9E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 152 170 2.9E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 179 195 2.9E-39 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 Gene3D G3DSA:3.30.360.10 168 320 5.7E-68 T 28-03-2018 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 156 163 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 Gene3D G3DSA:3.40.50.720 1 167 3.3E-70 T 28-03-2018 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 330 1.2E-133 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 PIRSF PIRSF000149 1 338 6.0E-129 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 109 1.7E-31 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 SUPERFAMILY SSF55347 157 318 1.12E-71 T 28-03-2018 CP478_RS07855 ba4dcc888df5474fb6337e0a39d836dd 339 SUPERFAMILY SSF51735 3 174 2.95E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS03925 ac60c3a340f7edd8c51f4e004129e86c 301 SUPERFAMILY SSF53335 15 216 2.91E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03925 ac60c3a340f7edd8c51f4e004129e86c 301 Gene3D G3DSA:3.40.50.150 3 255 1.0E-45 T 28-03-2018 CP478_RS03925 ac60c3a340f7edd8c51f4e004129e86c 301 Pfam PF04072 Leucine carboxyl methyltransferase 19 193 2.6E-62 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS03925 ac60c3a340f7edd8c51f4e004129e86c 301 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 193 3.5E-65 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Gene3D G3DSA:2.40.110.10 460 555 2.6E-34 T 28-03-2018 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 SUPERFAMILY SSF56645 383 581 9.69E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 SUPERFAMILY SSF47203 208 343 2.26E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 568 707 5.2E-11 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 212 328 4.3E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 462 544 2.9E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 SUPERFAMILY SSF47203 568 709 3.22E-11 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Gene3D G3DSA:1.20.140.10 207 329 4.0E-27 T 28-03-2018 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 SUPERFAMILY SSF56645 5 131 4.06E-12 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Gene3D G3DSA:1.10.540.10 342 459 1.7E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Gene3D G3DSA:1.10.540.10 2 113 1.2E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 369 458 1.5E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 105 1.7E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19530 3d348095545ebff7b74e276168cb6052 711 Gene3D G3DSA:1.20.140.10 556 711 6.9E-26 T 28-03-2018 CP478_RS08940 eca1cd1b557e18a52c74224a388ddccd 471 Gene3D G3DSA:1.20.1250.20 275 467 1.5E-7 T 28-03-2018 CP478_RS08940 eca1cd1b557e18a52c74224a388ddccd 471 Gene3D G3DSA:1.20.1250.20 10 194 1.7E-18 T 28-03-2018 CP478_RS08940 eca1cd1b557e18a52c74224a388ddccd 471 Pfam PF07690 Major Facilitator Superfamily 27 423 1.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS08940 eca1cd1b557e18a52c74224a388ddccd 471 SUPERFAMILY SSF103473 257 459 1.96E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS08940 eca1cd1b557e18a52c74224a388ddccd 471 SUPERFAMILY SSF103473 18 198 1.96E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 SUPERFAMILY SSF53187 10 182 9.24E-57 T 28-03-2018 CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 SUPERFAMILY SSF53187 282 376 9.24E-57 T 28-03-2018 CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 SUPERFAMILY SSF55031 170 274 1.7E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 PIRSF PIRSF037226 1 394 1.1E-144 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 Pfam PF01546 Peptidase family M20/M25/M40 89 344 7.4E-10 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 Gene3D G3DSA:3.40.630.10 4 394 1.2E-47 T 28-03-2018 CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 Pfam PF07687 Peptidase dimerisation domain 170 258 3.4E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS18110 365388c6cba03ae54488d5fc6676280a 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 352 5.4E-60 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 SUPERFAMILY SSF46689 280 330 1.86E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 Pfam PF12833 Helix-turn-helix domain 250 327 1.0E-13 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 Gene3D G3DSA:1.10.10.60 46 282 0.22 T 28-03-2018 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 SMART SM00342 244 326 9.8E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 Gene3D G3DSA:1.10.10.60 283 336 9.4E-12 T 28-03-2018 CP478_RS20410 1aa0b0eb9464fbdbc3e35cf58811844f 353 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 204 2.4E-37 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 35 487 5.8E-163 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 SUPERFAMILY SSF53271 276 494 4.59E-64 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 SUPERFAMILY SSF56235 35 293 6.86E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Pfam PF13522 Glutamine amidotransferase domain 93 235 2.6E-14 T 28-03-2018 CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 34 486 45.934 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Gene3D G3DSA:3.40.50.2020 265 472 2.8E-31 T 28-03-2018 CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 PIRSF PIRSF000485 31 502 8.6E-158 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Gene3D G3DSA:3.60.20.10 7 188 2.4E-37 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Gene3D G3DSA:3.60.20.10 189 264 1.6E-22 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CP478_RS04385 9ea603e7cb3154ca203078ac41bfda69 527 Pfam PF00156 Phosphoribosyl transferase domain 306 410 2.8E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS05900 839f27c9c39be69f8f03266785dd4461 297 Gene3D G3DSA:3.40.50.1820 14 296 3.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS05900 839f27c9c39be69f8f03266785dd4461 297 SUPERFAMILY SSF53474 13 294 2.45E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS05900 839f27c9c39be69f8f03266785dd4461 297 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 134 146 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site CP478_RS05900 839f27c9c39be69f8f03266785dd4461 297 Pfam PF07859 alpha/beta hydrolase fold 66 272 2.7E-43 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 Gene3D G3DSA:3.40.50.720 305 366 3.1E-15 T 28-03-2018 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 Gene3D G3DSA:3.40.50.720 1 213 1.3E-58 T 28-03-2018 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 Gene3D G3DSA:3.30.360.10 214 304 7.7E-35 T 28-03-2018 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 PIRSF PIRSF015578 3 366 8.8E-99 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 Pfam PF01658 Myo-inositol-1-phosphate synthase 203 311 1.0E-31 T 28-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 SUPERFAMILY SSF55347 201 311 7.33E-35 T 28-03-2018 CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 16 365 4.0E-222 T 28-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 SUPERFAMILY SSF51735 15 197 1.65E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00255 4c8d9dce3259610c67de50191a45aa04 367 SUPERFAMILY SSF51735 308 367 1.65E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 SMART SM00448 14 125 2.3E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 Gene3D G3DSA:3.40.50.2300 12 155 2.2E-37 T 28-03-2018 CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 PIRSF PIRSF036382 5 203 9.5E-76 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 SUPERFAMILY SSF52172 13 196 1.02E-57 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 Gene3D G3DSA:1.10.10.10 156 198 3.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 SMART SM01012 141 196 9.6E-23 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 Pfam PF03861 ANTAR domain 144 195 3.6E-19 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CP478_RS08895 2f8ded5ad16c211f57f847e2a2c8c5b2 205 Pfam PF00072 Response regulator receiver domain 16 125 2.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS20980 bef773015b1c8e1f41df45db91c99ead 181 Pfam PF00210 Ferritin-like domain 14 144 5.8E-33 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CP478_RS20980 bef773015b1c8e1f41df45db91c99ead 181 Gene3D G3DSA:1.20.1260.10 1 181 2.7E-46 T 28-03-2018 IPR012347 Ferritin-related CP478_RS20980 bef773015b1c8e1f41df45db91c99ead 181 SUPERFAMILY SSF47240 9 155 2.71E-43 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 SUPERFAMILY SSF55021 184 281 1.22E-24 T 28-03-2018 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 Pfam PF01842 ACT domain 207 267 1.4E-10 T 28-03-2018 IPR002912 ACT domain CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 PIRSF PIRSF001500 1 283 5.3E-60 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 Gene3D G3DSA:3.40.190.10 1 103 1.6E-26 T 28-03-2018 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 Gene3D G3DSA:3.40.190.10 104 172 1.4E-17 T 28-03-2018 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 SUPERFAMILY SSF53850 3 196 2.58E-45 T 28-03-2018 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 Pfam PF00800 Prephenate dehydratase 4 189 6.2E-43 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 Gene3D G3DSA:3.30.70.260 193 287 3.0E-30 T 28-03-2018 CP478_RS20965 1fd62db9d199d5e1a99c707753714560 321 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 229 236 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CP478_RS18605 7f4d9b63839bbb83bdf4a9acf92cf2a9 348 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 59 322 4.5E-80 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS18605 7f4d9b63839bbb83bdf4a9acf92cf2a9 348 Pfam PF04072 Leucine carboxyl methyltransferase 61 244 5.0E-65 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS18605 7f4d9b63839bbb83bdf4a9acf92cf2a9 348 SUPERFAMILY SSF53335 57 334 1.83E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18605 7f4d9b63839bbb83bdf4a9acf92cf2a9 348 Gene3D G3DSA:3.40.50.150 26 337 5.0E-59 T 28-03-2018 CP478_RS01985 4d1e2af03c443d7a90382204e28e0c36 251 Pfam PF02625 XdhC and CoxI family 11 76 1.5E-13 T 28-03-2018 IPR003777 XdhC- CoxI CP478_RS01985 4d1e2af03c443d7a90382204e28e0c36 251 Pfam PF13478 XdhC Rossmann domain 118 229 1.0E-19 T 28-03-2018 IPR027051 XdhC Rossmann domain CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 PRINTS PR01228 Eggshell protein signature 433 443 2.2E-5 T 28-03-2018 CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 PRINTS PR01228 Eggshell protein signature 473 491 2.2E-5 T 28-03-2018 CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 PRINTS PR01228 Eggshell protein signature 405 420 2.2E-5 T 28-03-2018 CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 PRINTS PR01228 Eggshell protein signature 319 330 2.2E-5 T 28-03-2018 CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 Pfam PF00934 PE family 1 93 2.2E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19615 1348b8456176bb348c2358e7d098da7e 584 SUPERFAMILY SSF140459 8 83 8.11E-26 T 28-03-2018 CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 Gene3D G3DSA:3.40.50.1820 33 353 1.1E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 SUPERFAMILY SSF49785 352 560 3.83E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 51 561 1.0E-157 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 SUPERFAMILY SSF53474 25 330 5.52E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 338 551 3.2E-21 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 SMART SM00939 322 555 1.6E-39 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 Gene3D G3DSA:2.60.120.260 354 558 6.8E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS06655 42161f55028b438a09b4713cbb29fdde 561 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 55 293 9.3E-39 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CP478_RS14230 c6bbc1cf6327f981bbd6a6807361ce7f 206 Pfam PF13785 Domain of unknown function (DUF4178) 55 191 4.7E-30 T 28-03-2018 IPR025235 Domain of unknown function DUF4178 CP478_RS14570 b79ce5fa019142a5f3e6423ceb8ee891 86 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 32 80 3.7E-19 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CP478_RS14570 b79ce5fa019142a5f3e6423ceb8ee891 86 SUPERFAMILY SSF46955 31 76 1.76E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS14570 b79ce5fa019142a5f3e6423ceb8ee891 86 Pfam PF12728 Helix-turn-helix domain 32 76 1.1E-10 T 28-03-2018 CP478_RS14570 b79ce5fa019142a5f3e6423ceb8ee891 86 Gene3D G3DSA:1.10.10.10 32 79 4.8E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09985 dc0635e3c60e004fc32873d7fb6ea6e1 677 SMART SM00327 486 670 1.5E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS09985 dc0635e3c60e004fc32873d7fb6ea6e1 677 Gene3D G3DSA:3.40.190.10 292 454 0.0012 T 28-03-2018 CP478_RS09985 dc0635e3c60e004fc32873d7fb6ea6e1 677 SUPERFAMILY SSF53300 491 659 2.31E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS09985 dc0635e3c60e004fc32873d7fb6ea6e1 677 Gene3D G3DSA:3.40.50.410 490 675 1.8E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS09985 dc0635e3c60e004fc32873d7fb6ea6e1 677 Pfam PF13531 Bacterial extracellular solute-binding protein 163 444 2.3E-17 T 28-03-2018 CP478_RS08105 3c5ac3e5b8a2ad9d78ca02c2e7c95265 377 SUPERFAMILY SSF52540 49 324 5.13E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08105 3c5ac3e5b8a2ad9d78ca02c2e7c95265 377 PIRSF PIRSF002849 15 354 2.0E-135 T 28-03-2018 CP478_RS08105 3c5ac3e5b8a2ad9d78ca02c2e7c95265 377 Gene3D G3DSA:3.40.50.300 54 220 1.4E-26 T 28-03-2018 CP478_RS08105 3c5ac3e5b8a2ad9d78ca02c2e7c95265 377 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 73 203 2.0E-60 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CP478_RS08105 3c5ac3e5b8a2ad9d78ca02c2e7c95265 377 Gene3D G3DSA:1.10.8.300 232 349 6.9E-31 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 332 4.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 Gene3D G3DSA:3.40.50.720 172 341 1.0E-26 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 5.9E-30 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 5.9E-30 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 5.9E-30 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.9E-30 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 5.9E-30 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 Gene3D G3DSA:3.50.50.60 1 171 3.0E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 SUPERFAMILY SSF55424 350 466 7.22E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 157 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 9.8E-45 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 Gene3D G3DSA:3.30.390.30 345 466 2.1E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 352 460 3.5E-24 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 PIRSF PIRSF000350 2 466 6.2E-67 T 28-03-2018 CP478_RS18095 c6ccf35fce08be9311874e929fdf0b61 471 SUPERFAMILY SSF51905 3 341 1.67E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06800 63f621e7f07310060c74117064746540 143 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 142 1.2E-46 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS06800 63f621e7f07310060c74117064746540 143 SUPERFAMILY SSF88723 5 138 2.83E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06800 63f621e7f07310060c74117064746540 143 Gene3D G3DSA:3.40.50.1010 2 139 1.9E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06800 63f621e7f07310060c74117064746540 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 15.384 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS06800 63f621e7f07310060c74117064746540 143 Pfam PF01850 PIN domain 3 134 2.8E-6 T 28-03-2018 IPR002716 PIN domain CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 Gene3D G3DSA:3.40.710.10 41 303 8.7E-33 T 28-03-2018 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 118 143 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 158 182 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 184 209 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 78 95 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 47 71 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 220 235 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 PRINTS PR00118 Beta-lactamase class A signature 237 252 1.3E-58 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 Pfam PF13354 Beta-lactamase enzyme family 68 277 3.9E-39 T 28-03-2018 CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 SUPERFAMILY SSF56601 43 301 8.53E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS11275 f6fbd6369c0cb55aea72290fe7c05db7 307 ProSitePatterns PS00146 Beta-lactamase class-A active site. 80 95 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 SUPERFAMILY SSF51735 9 245 5.44E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 Pfam PF00106 short chain dehydrogenase 12 203 2.8E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04165 0e1d8e685937d5054a19d1a01fd51864 275 Gene3D G3DSA:3.40.50.720 11 261 4.0E-53 T 28-03-2018 CP478_RS14130 5456d85235a9b8fdb81bdcacb9f2c416 340 SMART SM00729 62 289 0.0025 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS14130 5456d85235a9b8fdb81bdcacb9f2c416 340 Pfam PF04055 Radical SAM superfamily 69 237 6.8E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS14130 5456d85235a9b8fdb81bdcacb9f2c416 340 SUPERFAMILY SSF102114 63 275 8.76E-12 T 28-03-2018 CP478_RS14130 5456d85235a9b8fdb81bdcacb9f2c416 340 Gene3D G3DSA:3.20.20.70 44 321 1.3E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS01005 39f960b24a2f43b37729675ac6395a80 249 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 1 248 5.0E-124 T 28-03-2018 CP478_RS01005 39f960b24a2f43b37729675ac6395a80 249 Pfam PF10979 Protein of unknown function (DUF2786) 5 43 5.3E-13 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 CP478_RS01440 2a806c8e711075a80dbacdb34829357e 463 SUPERFAMILY SSF103473 27 455 3.01E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS01440 2a806c8e711075a80dbacdb34829357e 463 TIGRFAM TIGR00886 2A0108: nitrite transporter 45 412 1.0E-104 T 28-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 CP478_RS01440 2a806c8e711075a80dbacdb34829357e 463 Gene3D G3DSA:1.20.1250.20 246 459 1.6E-24 T 28-03-2018 CP478_RS01440 2a806c8e711075a80dbacdb34829357e 463 Gene3D G3DSA:1.20.1250.20 35 245 5.2E-12 T 28-03-2018 CP478_RS01440 2a806c8e711075a80dbacdb34829357e 463 Pfam PF07690 Major Facilitator Superfamily 58 414 3.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 SUPERFAMILY SSF51735 7 254 2.5E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.9E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 Gene3D G3DSA:3.40.50.10090 4 51 2.8E-10 T 28-03-2018 CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 9.3E-69 T 28-03-2018 CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 Gene3D G3DSA:3.40.50.720 52 255 1.8E-66 T 28-03-2018 CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 4.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10490 d2ae988038b8cb533d11049f3d6c7969 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS09385 fc13349a577bdafc6e1e7279148595a7 129 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 126 13.23 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS09385 fc13349a577bdafc6e1e7279148595a7 129 Pfam PF01850 PIN domain 2 116 2.8E-6 T 28-03-2018 IPR002716 PIN domain CP478_RS09385 fc13349a577bdafc6e1e7279148595a7 129 SUPERFAMILY SSF88723 2 121 9.48E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS09385 fc13349a577bdafc6e1e7279148595a7 129 Gene3D G3DSA:3.40.50.1010 1 129 8.8E-10 T 28-03-2018 IPR029060 PIN domain-like CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Pfam PF11799 impB/mucB/samB family C-terminal domain 247 343 4.0E-8 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Hamap MF_01113 DNA polymerase IV [dinB]. 6 345 28.253 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 SUPERFAMILY SSF56672 7 238 1.69E-66 T 28-03-2018 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Gene3D G3DSA:3.30.70.270 49 119 3.0E-16 T 28-03-2018 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Gene3D G3DSA:3.30.70.270 125 176 1.7E-15 T 28-03-2018 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Gene3D G3DSA:3.30.1490.100 251 346 2.4E-16 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Gene3D G3DSA:1.10.150.20 177 250 1.2E-13 T 28-03-2018 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 SUPERFAMILY SSF100879 246 343 1.82E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS16720 e551c724c0b13b33a124c6f559f0e69d 346 Pfam PF00817 impB/mucB/samB family 12 159 2.8E-39 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 SMART SM00382 163 348 6.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Gene3D G3DSA:3.40.50.300 96 369 1.5E-86 T 28-03-2018 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 94 1.3E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 20 482 5.0E-249 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Hamap MF_01347 ATP synthase subunit beta [atpB]. 18 482 54.462 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Gene3D G3DSA:2.40.10.170 13 95 2.8E-28 T 28-03-2018 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 SUPERFAMILY SSF47917 367 482 1.2E-47 T 28-03-2018 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 364 7.9E-63 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 SUPERFAMILY SSF52540 98 369 9.84E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 SUPERFAMILY SSF50615 20 95 6.54E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07175 6aa721e7a101d316ca008f29a00535fd 486 Gene3D G3DSA:1.10.1140.10 370 480 5.9E-37 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 385 8.2E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 SUPERFAMILY SSF56645 19 207 3.53E-24 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 Gene3D G3DSA:1.10.540.10 10 130 0.0071 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 Gene3D G3DSA:2.40.110.10 131 225 1.4E-10 T 28-03-2018 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 Gene3D G3DSA:1.20.140.10 226 389 1.5E-14 T 28-03-2018 CP478_RS01250 975dc9136c9e6614b72f38a7c8b964c1 568 SUPERFAMILY SSF47203 237 390 1.77E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 SUPERFAMILY SSF55874 3 144 1.17E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 139 3.9E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 Gene3D G3DSA:3.30.565.10 1 148 1.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 101 119 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 86 96 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 125 138 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 PRINTS PR00344 Bacterial sensor protein C-terminal signature 68 82 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS03210 2ff1c2c0997182f6036fde674b47099c 168 SMART SM00387 33 141 7.3E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS16110 f8aef57e86d765db3cff0986c6269e36 199 SUPERFAMILY SSF64288 14 178 3.61E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CP478_RS16110 f8aef57e86d765db3cff0986c6269e36 199 Gene3D G3DSA:3.40.1410.10 1 179 9.3E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CP478_RS16110 f8aef57e86d765db3cff0986c6269e36 199 Pfam PF01947 Protein of unknown function (DUF98) 24 173 1.5E-12 T 28-03-2018 IPR002800 Chorismate pyruvate-lyase Rv2949c-like CP478_RS08875 c64f7124c6fdd7f40c8d2e0bf735de11 485 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 460 1.2E-162 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CP478_RS08875 c64f7124c6fdd7f40c8d2e0bf735de11 485 PIRSF PIRSF006446 1 482 7.5E-132 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 Pfam PF08245 Mur ligase middle domain 69 308 9.4E-16 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 TIGRFAM TIGR01499 folC: bifunctional protein FolC 47 480 3.5E-90 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 Gene3D G3DSA:3.40.1190.10 19 336 2.7E-78 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 SUPERFAMILY SSF53623 27 333 9.46E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 Gene3D G3DSA:3.90.190.20 337 487 4.6E-25 T 28-03-2018 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 SUPERFAMILY SSF53244 337 483 1.72E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 413 3.9E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CP478_RS13375 1426216991eeaf159b8ec964657a0252 487 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 172 187 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 Gene3D G3DSA:3.40.50.720 206 251 6.9E-10 T 28-03-2018 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 Gene3D G3DSA:3.40.50.720 252 452 7.5E-51 T 28-03-2018 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 SUPERFAMILY SSF51735 209 451 9.17E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 414 434 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 287 298 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 360 379 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 381 398 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 334 350 1.1E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 347 375 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 360 379 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 287 298 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 340 348 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 220 448 9.1E-50 T 28-03-2018 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 Gene3D G3DSA:3.40.50.720 23 169 0.0011 T 28-03-2018 CP478_RS01310 2857de2a05c7d4aa8c0571c13b8379ba 454 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 214 391 2.9E-4 T 28-03-2018 CP478_RS20830 b4881e889f0f71b903f092a3a875688c 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 268 7.0E-57 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20830 b4881e889f0f71b903f092a3a875688c 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 268 4.7E-48 T 28-03-2018 IPR000150 Cof family GO:0016787 CP478_RS20830 b4881e889f0f71b903f092a3a875688c 273 Gene3D G3DSA:3.40.50.1000 4 273 6.8E-41 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20830 b4881e889f0f71b903f092a3a875688c 273 SUPERFAMILY SSF56784 8 271 1.3E-62 T 28-03-2018 IPR023214 HAD-like domain CP478_RS20830 b4881e889f0f71b903f092a3a875688c 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 241 1.7E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 Pfam PF03600 Citrate transporter 13 366 1.7E-55 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 PRINTS PR00758 Arsenical pump membrane protein signature 274 298 6.2E-10 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 6.2E-10 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 PRINTS PR00758 Arsenical pump membrane protein signature 396 420 6.2E-10 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 6.2E-10 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14725 655507b272cb7fa40142659acf1c82ae 428 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 6.2E-10 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 260 2.0E-90 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 SUPERFAMILY SSF51366 7 267 1.74E-56 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 259 5.9E-42 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 32.657 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 Gene3D G3DSA:3.20.20.70 3 272 1.9E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS07590 d48a82d0f716a56899b03a3edaca9743 274 SMART SM00934 17 260 1.8E-30 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 SUPERFAMILY SSF56645 73 250 3.01E-46 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 8.0E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 SUPERFAMILY SSF47203 239 396 6.93E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 Gene3D G3DSA:1.10.540.10 1 131 8.1E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 393 1.4E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 Gene3D G3DSA:2.40.110.10 132 228 2.7E-35 T 28-03-2018 CP478_RS17200 4a76d42b9eba235a22fd5561a78e8fd7 401 Gene3D G3DSA:1.20.140.10 229 401 7.8E-39 T 28-03-2018 CP478_RS10280 231dae0bcbdee4ec4961aaf807ded519 57 SUPERFAMILY SSF53335 1 57 2.08E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10280 231dae0bcbdee4ec4961aaf807ded519 57 Pfam PF04072 Leucine carboxyl methyltransferase 2 49 3.6E-17 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS10280 231dae0bcbdee4ec4961aaf807ded519 57 Gene3D G3DSA:3.40.50.150 1 57 1.6E-17 T 28-03-2018 CP478_RS20720 ea4e895384e8b98a136a3104b3f7b2ca 1094 Pfam PF14896 EmbC C-terminal domain 720 1092 5.9E-150 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CP478_RS20720 ea4e895384e8b98a136a3104b3f7b2ca 1094 Gene3D G3DSA:2.60.120.610 49 232 2.4E-56 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CP478_RS20720 ea4e895384e8b98a136a3104b3f7b2ca 1094 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 27 681 2.2E-275 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CP478_RS00280 3c374c522f95f10104419de11f2792fc 560 PIRSF PIRSF010361 27 524 2.1E-179 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane CP478_RS00280 3c374c522f95f10104419de11f2792fc 560 Pfam PF09594 Glycosyltransferase family 87 181 409 1.5E-14 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 183 211 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 46 232 0.0016 T 28-03-2018 CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 SUPERFAMILY SSF51735 44 290 6.56E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 215 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 252 272 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 234 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 186 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 Gene3D G3DSA:3.40.50.720 9 291 8.9E-71 T 28-03-2018 CP478_RS19060 4db3b409e279fbaf83d1f411b605607e 314 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 287 9.9E-59 T 28-03-2018 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 SMART SM01374 1 122 3.1E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 4.6E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 Gene3D G3DSA:2.40.150.20 1 122 7.8E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.3E-57 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 SUPERFAMILY SSF50193 2 122 7.72E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CP478_RS03870 842cb09940db4cc453ca06f4fb7503d8 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.794 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CP478_RS14545 f2852ef8c127984ef78e524e99b29827 208 Pfam PF05119 Phage terminase, small subunit 96 188 8.2E-19 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CP478_RS14545 f2852ef8c127984ef78e524e99b29827 208 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 88 204 3.2E-20 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CP478_RS00945 33a6cc8cc5072496563335015d9fd66b 530 Gene3D G3DSA:1.10.287.1060 171 264 0.0013 T 28-03-2018 CP478_RS00945 33a6cc8cc5072496563335015d9fd66b 530 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 312 7.7E-98 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00945 33a6cc8cc5072496563335015d9fd66b 530 Pfam PF02470 MlaD protein 47 120 1.6E-12 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS00945 33a6cc8cc5072496563335015d9fd66b 530 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 173 291 1.9E-6 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS09045 dc464d3481716e986681259d34e9aace 404 SUPERFAMILY SSF56266 19 400 1.44E-120 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 Gene3D G3DSA:3.30.2330.10 200 278 1.6E-22 T 28-03-2018 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 31 402 1.0E-157 T 28-03-2018 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 404 131.988 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 Pfam PF01960 ArgJ family 24 404 2.0E-127 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 14 403 1.3E-109 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS09045 dc464d3481716e986681259d34e9aace 404 Gene3D G3DSA:3.60.70.12 1 199 2.0E-68 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 5.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 5.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 Gene3D G3DSA:1.10.10.60 7 68 1.0E-17 T 28-03-2018 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 Gene3D G3DSA:1.10.357.10 69 213 3.6E-9 T 28-03-2018 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 SUPERFAMILY SSF48498 92 211 3.56E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 SUPERFAMILY SSF46689 13 83 1.8E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16730 a84d6be5b430f2dcccb2eca894479573 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15735 7fc854f29768e8ec3fea8b00ef9af9a4 173 Gene3D G3DSA:3.40.30.10 38 173 1.2E-26 T 28-03-2018 CP478_RS15735 7fc854f29768e8ec3fea8b00ef9af9a4 173 Pfam PF00578 AhpC/TSA family 43 144 4.1E-15 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS15735 7fc854f29768e8ec3fea8b00ef9af9a4 173 SUPERFAMILY SSF52833 42 165 6.02E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS19255 e206e778d7dcd0631fd8aa37d93fc453 394 Gene3D G3DSA:3.40.47.10 213 383 2.8E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19255 e206e778d7dcd0631fd8aa37d93fc453 394 PIRSF PIRSF000429 2 382 6.9E-19 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS19255 e206e778d7dcd0631fd8aa37d93fc453 394 SUPERFAMILY SSF53901 8 122 5.28E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19255 e206e778d7dcd0631fd8aa37d93fc453 394 SUPERFAMILY SSF53901 184 381 5.28E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19255 e206e778d7dcd0631fd8aa37d93fc453 394 Gene3D G3DSA:3.40.47.10 3 212 1.3E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 Gene3D G3DSA:3.20.20.70 5 469 7.7E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 SUPERFAMILY SSF51412 202 473 5.49E-91 T 28-03-2018 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 SUPERFAMILY SSF51412 11 93 5.49E-91 T 28-03-2018 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 SMART SM01240 11 474 2.2E-186 T 28-03-2018 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 Pfam PF00571 CBS domain 97 139 3.4E-5 T 28-03-2018 IPR000644 CBS domain CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 473 4.1E-102 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 476 3.5E-281 T 28-03-2018 IPR005991 IMP dehydrogenase-related 1 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 SUPERFAMILY SSF54631 93 202 5.12E-15 T 28-03-2018 CP478_RS10025 fc12f2cf9a052324bb24f67b6d661dec 478 PIRSF PIRSF000130 3 478 3.1E-146 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 Pfam PF00128 Alpha amylase, catalytic domain 54 399 9.8E-81 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 SMART SM00642 39 424 4.4E-130 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 Gene3D G3DSA:3.20.20.80 367 487 3.1E-21 T 28-03-2018 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 Gene3D G3DSA:3.90.400.10 131 203 4.9E-32 T 28-03-2018 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 Gene3D G3DSA:3.20.20.470 14 121 2.8E-35 T 28-03-2018 CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 SUPERFAMILY SSF51445 30 484 9.16E-124 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS13510 7abb51fe508385aa801182c9ae5b1e28 546 Gene3D G3DSA:3.20.20.470 204 366 3.3E-35 T 28-03-2018 CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 Gene3D G3DSA:1.10.287.1060 1 101 3.3E-4 T 28-03-2018 CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 Pfam PF08237 PE-PPE domain 172 398 2.7E-79 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 SUPERFAMILY SSF53474 141 338 6.83E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 Pfam PF00934 PE family 1 93 7.7E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 Gene3D G3DSA:3.40.50.1820 133 345 1.9E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00880 aecf44589c6461a3b6a39b34f624c029 502 SUPERFAMILY SSF140459 8 83 8.11E-23 T 28-03-2018 CP478_RS01130 7dd3da7681663d30283a4226f436bdef 263 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 72 243 2.4E-34 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CP478_RS01130 7dd3da7681663d30283a4226f436bdef 263 Gene3D G3DSA:3.40.50.150 38 261 9.2E-24 T 28-03-2018 CP478_RS01130 7dd3da7681663d30283a4226f436bdef 263 SUPERFAMILY SSF53335 73 249 8.75E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01130 7dd3da7681663d30283a4226f436bdef 263 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 31 253 25.916 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CP478_RS01130 7dd3da7681663d30283a4226f436bdef 263 Pfam PF02390 Putative methyltransferase 77 247 2.2E-54 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CP478_RS13595 0c2ddc66e583a4ddded6419dbc10dfbe 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS13595 0c2ddc66e583a4ddded6419dbc10dfbe 256 SUPERFAMILY SSF52096 2 252 1.38E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS13595 0c2ddc66e583a4ddded6419dbc10dfbe 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 219 4.5E-47 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS13595 0c2ddc66e583a4ddded6419dbc10dfbe 256 Gene3D G3DSA:3.90.226.10 1 256 5.6E-57 T 28-03-2018 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 Pfam PF04055 Radical SAM superfamily 121 290 2.0E-21 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 364 62.88 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 PIRSF PIRSF006004 12 362 8.4E-112 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 22 361 2.4E-94 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 Gene3D G3DSA:3.20.20.70 25 358 1.6E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS15740 05c8ecfa53f49eaffc403e3f8179e410 364 SUPERFAMILY SSF102114 110 334 1.1E-16 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Pfam PF02142 MGS-like domain 986 1078 3.2E-21 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 724 738 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF56059 133 405 1.68E-100 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF52440 2 132 4.17E-41 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 244 261 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 302 331 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 384 402 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 209 228 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 173 185 1.2E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.40.50.20 541 669 3.5E-57 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1099 12.76 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SMART SM00851 985 1078 1.7E-26 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.30.1490.20 670 760 6.7E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.30.470.20 761 963 2.4E-36 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF52335 972 1107 3.4E-34 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF56059 688 963 3.71E-95 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SMART SM01096 426 549 1.1E-56 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.40.50.1380 964 1110 1.6E-46 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 853 860 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.40.50.20 4 117 1.6E-31 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF52440 563 689 1.87E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1088 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 2.2E-36 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 SUPERFAMILY SSF48108 401 552 3.53E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 688 889 2.1E-34 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 133 339 2.8E-65 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:1.10.1030.10 417 540 9.7E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 Gene3D G3DSA:3.30.470.20 125 407 8.0E-64 T 28-03-2018 CP478_RS07585 70783f3b988a314c27617f1cd7aa1682 1115 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 302 309 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 SUPERFAMILY SSF52402 171 308 1.93E-28 T 28-03-2018 CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 SUPERFAMILY SSF52402 10 165 4.44E-25 T 28-03-2018 CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 PRINTS PR01438 Universal stress protein signature 268 280 6.8E-16 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 PRINTS PR01438 Universal stress protein signature 169 187 6.8E-16 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 PRINTS PR01438 Universal stress protein signature 286 308 6.8E-16 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 Gene3D G3DSA:3.40.50.620 164 315 6.9E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 Pfam PF00582 Universal stress protein family 172 308 2.2E-21 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 Pfam PF00582 Universal stress protein family 10 159 4.0E-24 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS10885 fb43e0601c22efb7052708a750e71fdd 317 Gene3D G3DSA:3.40.50.620 4 163 2.1E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 327 1.1E-131 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 Gene3D G3DSA:3.20.20.70 1 329 1.1E-141 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 SUPERFAMILY SSF51569 4 328 1.03E-125 T 28-03-2018 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PIRSF PIRSF001415 1 329 2.0E-142 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 247 259 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 247 263 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 272 287 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 302 321 1.4E-59 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS02740 4dbbcd0ac852bb4168417692daa12a6d 329 SMART SM01004 6 328 2.3E-202 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CP478_RS11990 bc6bffd1fd2df0a8ce232ba4574a4fb9 236 Pfam PF11241 Protein of unknown function (DUF3043) 48 232 8.1E-58 T 28-03-2018 IPR021403 Protein of unknown function DUF3043 CP478_RS15720 72ed4edc2db9722b30823ecc87f42b52 193 Gene3D G3DSA:2.30.180.10 57 193 1.2E-27 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15720 72ed4edc2db9722b30823ecc87f42b52 193 SMART SM00554 97 192 3.6E-24 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15720 72ed4edc2db9722b30823ecc87f42b52 193 Pfam PF02469 Fasciclin domain 69 191 6.6E-27 T 28-03-2018 IPR000782 FAS1 domain CP478_RS15720 72ed4edc2db9722b30823ecc87f42b52 193 SUPERFAMILY SSF82153 36 192 1.31E-37 T 28-03-2018 IPR000782 FAS1 domain CP478_RS01845 02e4e44bf36f7d544fa4ffae68337456 136 Gene3D G3DSA:3.90.550.10 4 132 8.1E-9 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01845 02e4e44bf36f7d544fa4ffae68337456 136 SUPERFAMILY SSF53448 6 116 2.13E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01845 02e4e44bf36f7d544fa4ffae68337456 136 Pfam PF12804 MobA-like NTP transferase domain 8 116 5.3E-14 T 28-03-2018 IPR025877 MobA-like NTP transferase CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.9E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 Gene3D G3DSA:1.10.10.60 6 65 7.4E-18 T 28-03-2018 CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 SUPERFAMILY SSF46689 9 87 3.9E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 SUPERFAMILY SSF48498 82 197 1.51E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19440 5a7661b185de78d3e54e00d8b597baff 200 Gene3D G3DSA:1.10.357.10 66 199 2.3E-22 T 28-03-2018 CP478_RS20695 5dd0fcc6e06d6730a41069e6a917fa54 161 SUPERFAMILY SSF54534 89 157 1.02E-9 T 28-03-2018 CP478_RS20695 5dd0fcc6e06d6730a41069e6a917fa54 161 Gene3D G3DSA:1.10.287.180 10 76 1.7E-6 T 28-03-2018 CP478_RS20695 5dd0fcc6e06d6730a41069e6a917fa54 161 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 89 158 2.3E-10 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CP478_RS20695 5dd0fcc6e06d6730a41069e6a917fa54 161 PIRSF PIRSF006092 4 160 3.6E-14 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CP478_RS20695 5dd0fcc6e06d6730a41069e6a917fa54 161 Gene3D G3DSA:3.10.50.30 84 161 1.1E-14 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 SUPERFAMILY SSF48498 107 181 2.67E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 SUPERFAMILY SSF46689 5 72 4.51E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.9E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 Gene3D G3DSA:1.10.10.60 4 37 1.2E-13 T 28-03-2018 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 Gene3D G3DSA:1.10.357.10 67 187 3.2E-8 T 28-03-2018 CP478_RS08080 47c982cd367b3393f20e4756cdb7cbe9 187 Gene3D G3DSA:1.10.260.40 38 66 1.6E-11 T 28-03-2018 CP478_RS18755 3ec1fb3b3cdb6884249d1209aacc8435 251 PIRSF PIRSF003073 1 251 7.6E-82 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CP478_RS18755 3ec1fb3b3cdb6884249d1209aacc8435 251 SUPERFAMILY SSF52540 67 226 6.04E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18755 3ec1fb3b3cdb6884249d1209aacc8435 251 Gene3D G3DSA:3.40.50.300 47 235 9.1E-17 T 28-03-2018 CP478_RS18755 3ec1fb3b3cdb6884249d1209aacc8435 251 Pfam PF01695 IstB-like ATP binding protein 58 233 5.8E-42 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CP478_RS18755 3ec1fb3b3cdb6884249d1209aacc8435 251 SMART SM00382 100 234 6.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 Gene3D G3DSA:1.20.140.10 164 319 4.1E-29 T 28-03-2018 CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 SUPERFAMILY SSF47203 187 318 1.93E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 Gene3D G3DSA:1.10.540.10 1 120 2.1E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 102 2.2E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 183 318 1.3E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19470 0dfc6a576c2e861bcd798bd9ce0bb757 319 SUPERFAMILY SSF56645 3 123 1.01E-14 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS07960 7a92693071d8a645d676b71c7526bbdd 308 Pfam PF01040 UbiA prenyltransferase family 35 284 2.6E-58 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CP478_RS07960 7a92693071d8a645d676b71c7526bbdd 308 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 22 300 7.3E-96 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CP478_RS07960 7a92693071d8a645d676b71c7526bbdd 308 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 19 301 18.595 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 Gene3D G3DSA:1.10.10.60 5 78 2.6E-16 T 28-03-2018 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 SUPERFAMILY SSF48498 102 204 9.78E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 Gene3D G3DSA:1.10.357.10 79 225 4.8E-13 T 28-03-2018 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 SUPERFAMILY SSF46689 23 97 2.0E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 80 3.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16685 cf257b802e8ae44ec775366c53c09688 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS12805 40f71f9e83328c8a9a7bf0cfbad1a37d 98 SUPERFAMILY SSF140453 4 97 3.4E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS12805 40f71f9e83328c8a9a7bf0cfbad1a37d 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 1.6E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS12805 40f71f9e83328c8a9a7bf0cfbad1a37d 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 6.8E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS12805 40f71f9e83328c8a9a7bf0cfbad1a37d 98 Gene3D G3DSA:1.10.287.1060 1 98 4.5E-14 T 28-03-2018 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 SUPERFAMILY SSF82866 504 701 4.97E-26 T 28-03-2018 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 Gene3D G3DSA:1.20.1640.10 482 700 3.1E-31 T 28-03-2018 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 Gene3D G3DSA:1.20.1640.10 83 336 2.0E-27 T 28-03-2018 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 SUPERFAMILY SSF82866 154 337 1.96E-27 T 28-03-2018 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 Pfam PF03176 MMPL family 117 369 3.3E-37 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS01100 80660a6761db4d026ddfbd0eee847c55 966 Pfam PF03176 MMPL family 450 704 1.2E-35 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS10130 a8a589978d926acf728450f6072a827a 251 Pfam PF03473 MOSC domain 80 193 1.2E-22 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CP478_RS10130 a8a589978d926acf728450f6072a827a 251 Gene3D G3DSA:2.40.33.20 10 247 2.0E-41 T 28-03-2018 CP478_RS10130 a8a589978d926acf728450f6072a827a 251 SUPERFAMILY SSF50800 19 240 1.99E-52 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CP478_RS15015 21fac1f1034d9e981aca389edc676d75 149 SUPERFAMILY SSF54427 14 142 9.62E-37 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS15015 21fac1f1034d9e981aca389edc676d75 149 Gene3D G3DSA:3.10.450.50 1 149 5.1E-23 T 28-03-2018 CP478_RS15015 21fac1f1034d9e981aca389edc676d75 149 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 16 134 1.7E-52 T 28-03-2018 IPR013100 Limonene-1,2-epoxide hydrolase CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 SUPERFAMILY SSF51735 10 251 4.17E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 251 1.3E-65 T 28-03-2018 CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 Gene3D G3DSA:3.40.50.720 51 256 1.3E-58 T 28-03-2018 CP478_RS15620 7a0469d8da92664ee9ac725bae8f93e4 258 Gene3D G3DSA:3.40.50.720 3 50 1.4E-7 T 28-03-2018 CP478_RS10870 4eecb02e51c04470d34413bc0f7ea2b2 90 Pfam PF07371 Protein of unknown function (DUF1490) 2 86 2.4E-38 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS10870 4eecb02e51c04470d34413bc0f7ea2b2 90 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 90 3.0E-30 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 Pfam PF00067 Cytochrome P450 226 402 3.8E-28 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 SUPERFAMILY SSF48264 34 430 1.19E-85 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 178 193 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 322 349 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 305 316 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 161 177 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 372 381 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 350 365 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 114 125 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 221 243 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 PRINTS PR00359 B-class P450 signature 381 392 1.1E-49 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS10225 07cdab1e829ba00daa6cd1537268276c 438 Gene3D G3DSA:1.10.630.10 25 429 2.0E-70 T 28-03-2018 CP478_RS06195 95d9e7dc6609bc4cd1df5aada1e30fd6 576 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 573 9.7E-286 T 28-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane CP478_RS14260 4d8672c7a38e6ba8d0c5bfec6a645f69 146 Gene3D G3DSA:3.40.50.1010 1 143 6.6E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS14260 4d8672c7a38e6ba8d0c5bfec6a645f69 146 Pfam PF01850 PIN domain 3 137 1.3E-12 T 28-03-2018 IPR002716 PIN domain CP478_RS14260 4d8672c7a38e6ba8d0c5bfec6a645f69 146 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 143 15.921 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS14260 4d8672c7a38e6ba8d0c5bfec6a645f69 146 SUPERFAMILY SSF88723 1 141 4.21E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS14260 4d8672c7a38e6ba8d0c5bfec6a645f69 146 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 146 1.6E-57 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS07750 da9b9d88d65891e688898155fa2be5da 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 13 156 26.634 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07750 da9b9d88d65891e688898155fa2be5da 160 SUPERFAMILY SSF52121 13 157 1.06E-50 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07750 da9b9d88d65891e688898155fa2be5da 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 18 151 1.9E-47 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07750 da9b9d88d65891e688898155fa2be5da 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 150 2.0E-39 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07750 da9b9d88d65891e688898155fa2be5da 160 Gene3D G3DSA:3.40.50.960 3 158 4.3E-56 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS05350 fbb1cc35b600836fa778a2607ab4f468 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 48 2.4E-13 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS05350 fbb1cc35b600836fa778a2607ab4f468 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.038 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS05350 fbb1cc35b600836fa778a2607ab4f468 57 SUPERFAMILY SSF57829 1 38 9.16E-8 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CP478_RS05350 fbb1cc35b600836fa778a2607ab4f468 57 Pfam PF01783 Ribosomal L32p protein family 2 46 2.1E-11 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 4 306 4.0E-86 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 Gene3D G3DSA:3.40.50.1370 167 309 1.6E-41 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 3 309 39.31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 SUPERFAMILY SSF53671 2 307 6.02E-91 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 305 2.8E-20 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 140 151 1.8E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.8E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 1.8E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 1.8E-19 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 Gene3D G3DSA:3.40.50.1370 1 166 1.9E-63 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 139 156 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 223 232 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 PRINTS PR00101 Aspartate carbamoyltransferase signature 288 302 1.1E-31 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CP478_RS07565 7e193f3579b930ff70071a9954b1a4d3 319 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 152 6.8E-40 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CP478_RS04035 1aaba17b6a50538ddea3b7fdc58069ba 168 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 47 6.9E-10 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CP478_RS04035 1aaba17b6a50538ddea3b7fdc58069ba 168 Gene3D G3DSA:1.10.10.10 4 62 4.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04035 1aaba17b6a50538ddea3b7fdc58069ba 168 Pfam PF12728 Helix-turn-helix domain 4 48 8.3E-11 T 28-03-2018 CP478_RS04035 1aaba17b6a50538ddea3b7fdc58069ba 168 SUPERFAMILY SSF46955 4 58 2.75E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 Pfam PF02548 Ketopantoate hydroxymethyltransferase 20 276 6.4E-106 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 21 281 42.404 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 Gene3D G3DSA:3.20.20.60 10 281 7.4E-83 T 28-03-2018 CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 PIRSF PIRSF000388 12 281 2.5E-114 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 SUPERFAMILY SSF51621 21 280 2.08E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS12095 b39a8fdd4dfef38e32151cd2418e5486 281 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 20 281 2.1E-93 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CP478_RS11945 ed1b1299ce96e0a100d314a059f78520 214 Pfam PF10812 Protein of unknown function (DUF2561) 1 206 1.7E-102 T 28-03-2018 IPR024381 Protein of unknown function DUF2561 CP478_RS11945 ed1b1299ce96e0a100d314a059f78520 214 ProDom PD111926 TRANSMEMBRANE MEMBRANE RV2197C/MT2253 PROBABLE ML0878 1 212 2.0E-108 T 28-03-2018 IPR024381 Protein of unknown function DUF2561 CP478_RS12590 9f6aaa6ee7085c6b5d4fcf1ceb642e6b 54 Gene3D G3DSA:1.10.10.10 1 54 3.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17170 ac762d8decfa39dd7d8ba91eceb6634e 132 Gene3D G3DSA:1.10.287.1060 20 105 2.9E-8 T 28-03-2018 CP478_RS17170 ac762d8decfa39dd7d8ba91eceb6634e 132 Pfam PF00823 PPE family 6 129 1.4E-40 T 28-03-2018 IPR000030 PPE family CP478_RS17170 ac762d8decfa39dd7d8ba91eceb6634e 132 SUPERFAMILY SSF140459 2 121 6.28E-39 T 28-03-2018 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 74 107 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 Pfam PF01565 FAD binding domain 74 209 1.8E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 Pfam PF08031 Berberine and berberine like 439 472 7.5E-8 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 SUPERFAMILY SSF56176 38 241 1.36E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 Gene3D G3DSA:3.30.465.10 129 268 3.4E-32 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS00345 2c20e401c4a9677fa65baa6f7464463c 479 Gene3D G3DSA:3.30.43.10 47 126 1.5E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS05385 8f8c1ded3db14f7a77dc32177c239c41 248 Gene3D G3DSA:3.40.50.300 2 241 1.3E-67 T 28-03-2018 CP478_RS05385 8f8c1ded3db14f7a77dc32177c239c41 248 SMART SM00382 35 238 3.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS05385 8f8c1ded3db14f7a77dc32177c239c41 248 Pfam PF00005 ABC transporter 26 174 4.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS05385 8f8c1ded3db14f7a77dc32177c239c41 248 SUPERFAMILY SSF52540 6 240 1.43E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05385 8f8c1ded3db14f7a77dc32177c239c41 248 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS19420 3285a7680f989a06ecc324a1d10f9245 355 SUPERFAMILY SSF51412 3 249 3.05E-59 T 28-03-2018 CP478_RS19420 3285a7680f989a06ecc324a1d10f9245 355 SUPERFAMILY SSF51412 309 342 3.05E-59 T 28-03-2018 CP478_RS19420 3285a7680f989a06ecc324a1d10f9245 355 Pfam PF03060 Nitronate monooxygenase 5 341 4.4E-113 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS19420 3285a7680f989a06ecc324a1d10f9245 355 SMART SM01240 1 277 0.0078 T 28-03-2018 CP478_RS19420 3285a7680f989a06ecc324a1d10f9245 355 Gene3D G3DSA:3.20.20.70 2 353 1.7E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS05590 87a9e2f5b0c28b9e33e134f2fa384409 325 Gene3D G3DSA:1.10.287.1080 86 203 2.4E-32 T 28-03-2018 CP478_RS05590 87a9e2f5b0c28b9e33e134f2fa384409 325 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 107 181 5.0E-24 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CP478_RS05590 87a9e2f5b0c28b9e33e134f2fa384409 325 SUPERFAMILY SSF101386 90 182 4.11E-17 T 28-03-2018 CP478_RS07490 8bb01a427241633d8df1415a082f46d5 128 Gene3D G3DSA:3.30.750.24 13 128 2.0E-15 T 28-03-2018 IPR002645 STAS domain CP478_RS07490 8bb01a427241633d8df1415a082f46d5 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 122 5.8E-36 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CP478_RS07490 8bb01a427241633d8df1415a082f46d5 128 SUPERFAMILY SSF52091 19 127 8.44E-19 T 28-03-2018 IPR002645 STAS domain CP478_RS07490 8bb01a427241633d8df1415a082f46d5 128 Pfam PF01740 STAS domain 19 124 1.6E-17 T 28-03-2018 IPR002645 STAS domain CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 SMART SM00798 141 458 1.5E-170 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Pfam PF02142 MGS-like domain 22 135 8.8E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 SUPERFAMILY SSF52335 10 198 2.29E-61 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 SMART SM00851 22 136 9.2E-47 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 PIRSF PIRSF000414 5 523 2.6E-187 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Gene3D G3DSA:3.40.50.1380 1 198 3.2E-65 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 SUPERFAMILY SSF53927 218 523 1.1E-111 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Gene3D G3DSA:3.40.140.20 370 513 3.0E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 523 6.0E-166 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 457 1.3E-107 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Gene3D G3DSA:3.40.140.20 235 368 4.1E-46 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS05225 d4a473a4da472433db7e9540b6f57aae 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 523 41.273 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS20770 86ef0cd802ed7720b455d9da6e9f0d4a 299 Gene3D G3DSA:3.40.50.1820 28 294 3.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20770 86ef0cd802ed7720b455d9da6e9f0d4a 299 Pfam PF00756 Putative esterase 43 293 1.2E-49 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS20770 86ef0cd802ed7720b455d9da6e9f0d4a 299 SUPERFAMILY SSF53474 34 294 2.07E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01740 0c97761bb7b8599e650dfd7cc85bae63 74 Gene3D G3DSA:3.40.50.150 11 74 7.1E-4 T 28-03-2018 CP478_RS01740 0c97761bb7b8599e650dfd7cc85bae63 74 SUPERFAMILY SSF53335 18 73 8.8E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS00105 fa88e30266d64cc701cb19a9b035543b 514 Gene3D G3DSA:3.60.40.10 8 238 1.1E-39 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS00105 fa88e30266d64cc701cb19a9b035543b 514 SUPERFAMILY SSF81606 7 237 1.44E-64 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS00105 fa88e30266d64cc701cb19a9b035543b 514 SMART SM00332 5 236 2.1E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS00105 fa88e30266d64cc701cb19a9b035543b 514 Pfam PF13672 Protein phosphatase 2C 21 201 2.0E-13 T 28-03-2018 CP478_RS00105 fa88e30266d64cc701cb19a9b035543b 514 SMART SM00331 14 238 3.7E-58 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CP478_RS15120 1227e9232a9143baf9ba9404d7703e5a 89 Pfam PF07704 Rv0623-like transcription factor 1 88 3.1E-20 T 28-03-2018 IPR011660 Antitoxin VapB-like CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 SMART SM00479 42 216 5.0E-54 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 SUPERFAMILY SSF82771 249 327 1.57E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 Gene3D G3DSA:3.40.1440.10 236 331 2.7E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 SUPERFAMILY SSF53098 36 227 1.44E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 Gene3D G3DSA:3.30.420.10 28 200 4.7E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 Gene3D G3DSA:1.20.5.140 201 219 7.2E-8 T 28-03-2018 CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 SMART SM00465 249 330 2.8E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 Pfam PF00929 Exonuclease 44 207 9.3E-36 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 37 218 7.9E-27 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS11915 0d4894c3e414143484ed1763cca80389 645 Pfam PF01541 GIY-YIG catalytic domain 251 295 3.5E-5 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 SUPERFAMILY SSF63411 12 218 5.13E-57 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 46 69 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 Gene3D G3DSA:3.30.830.10 3 230 2.7E-60 T 28-03-2018 CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 Pfam PF05193 Peptidase M16 inactive domain 180 354 7.9E-38 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 SUPERFAMILY SSF63411 242 424 1.83E-42 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 Gene3D G3DSA:3.30.830.10 239 436 5.6E-41 T 28-03-2018 CP478_RS15235 816fcd1cd5bf90806fba878ce9cff94a 438 Pfam PF00675 Insulinase (Peptidase family M16) 25 171 3.4E-35 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CP478_RS20320 ce033fbef2e6329faac00afa1e7ad848 420 Gene3D G3DSA:3.40.50.150 128 403 5.4E-56 T 28-03-2018 CP478_RS20320 ce033fbef2e6329faac00afa1e7ad848 420 PIRSF PIRSF003085 1 420 6.7E-126 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS20320 ce033fbef2e6329faac00afa1e7ad848 420 Pfam PF02353 Mycolic acid cyclopropane synthetase 130 398 1.4E-99 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20320 ce033fbef2e6329faac00afa1e7ad848 420 SUPERFAMILY SSF53335 141 403 1.29E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS06255 7f25188ad9f1915d1e24b46f0ecd1b63 268 Gene3D G3DSA:3.90.226.10 15 225 1.3E-51 T 28-03-2018 CP478_RS06255 7f25188ad9f1915d1e24b46f0ecd1b63 268 Gene3D G3DSA:1.10.12.10 226 268 5.8E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS06255 7f25188ad9f1915d1e24b46f0ecd1b63 268 SUPERFAMILY SSF52096 15 268 4.02E-69 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS06255 7f25188ad9f1915d1e24b46f0ecd1b63 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 267 3.6E-49 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS15510 cc611ef507b6036a166b80e4413f7e56 439 Pfam PF01554 MatE 19 178 3.0E-27 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CP478_RS15510 cc611ef507b6036a166b80e4413f7e56 439 Pfam PF01554 MatE 239 393 1.8E-15 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CP478_RS15510 cc611ef507b6036a166b80e4413f7e56 439 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 410 2.9E-101 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 Gene3D G3DSA:1.10.10.10 3 99 8.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 SUPERFAMILY SSF46785 6 91 9.67E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 SMART SM00418 13 91 5.2E-30 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS10875 fb6344df0efa3cdd2f9b6bdd433ef8f9 118 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 1.4E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS03990 c093ba71cfa8d4f4545c138e17a36e4a 165 Gene3D G3DSA:1.10.10.10 2 164 6.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03990 c093ba71cfa8d4f4545c138e17a36e4a 165 SMART SM00347 47 148 3.9E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS03990 c093ba71cfa8d4f4545c138e17a36e4a 165 SUPERFAMILY SSF46785 24 162 1.09E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03990 c093ba71cfa8d4f4545c138e17a36e4a 165 Pfam PF01047 MarR family 57 113 5.5E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 SUPERFAMILY SSF143548 17 157 1.96E-40 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 Pfam PF03315 Serine dehydratase beta chain 4 156 5.3E-54 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 7.6E-210 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 Pfam PF03313 Serine dehydratase alpha chain 187 451 1.0E-95 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 Gene3D G3DSA:1.10.4100.10 263 448 5.6E-31 T 28-03-2018 CP478_RS00385 9bbc1e3ec7a2cdbae79467b0cf22ac42 461 Gene3D G3DSA:3.30.1330.90 11 159 1.9E-52 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CP478_RS14485 c979962f8d8c9c61650693287c9ed1fc 57 Gene3D G3DSA:2.30.30.110 1 55 1.9E-4 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS14485 c979962f8d8c9c61650693287c9ed1fc 57 SUPERFAMILY SSF50118 1 52 2.13E-5 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 Gene3D G3DSA:3.30.930.10 10 339 4.2E-72 T 28-03-2018 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 SUPERFAMILY SSF46589 17 101 3.56E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 49 333 1.4E-83 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 90 3.7E-15 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 Pfam PF01409 tRNA synthetases class II core domain (F) 95 334 7.9E-96 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 SUPERFAMILY SSF55681 95 333 3.98E-71 T 28-03-2018 CP478_RS09025 1c9de4fcc38f137d1dc91269bc769d76 341 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 337 44.964 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 ProSitePatterns PS00622 LuxR-type HTH domain signature. 835 862 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 SUPERFAMILY SSF46894 813 879 9.86E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 SUPERFAMILY SSF52540 7 239 2.12E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 SMART SM00421 818 875 2.5E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 851 863 4.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 821 835 4.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 835 851 4.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 Gene3D G3DSA:1.25.40.10 137 573 2.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 Gene3D G3DSA:1.25.40.10 574 791 1.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 Gene3D G3DSA:3.40.50.300 1 132 1.8E-9 T 28-03-2018 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 Gene3D G3DSA:1.10.10.10 820 880 4.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 Pfam PF00196 Bacterial regulatory proteins, luxR family 820 874 7.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00364 Disease resistance protein signature 77 91 1.0E-5 T 28-03-2018 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00364 Disease resistance protein signature 10 25 1.0E-5 T 28-03-2018 CP478_RS04855 494d4807ee6c818960acbb8eab514323 882 PRINTS PR00364 Disease resistance protein signature 172 186 1.0E-5 T 28-03-2018 CP478_RS10230 de382d3fb794ce24db8bd99c532b8df1 140 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 27 140 3.3E-29 T 28-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 CP478_RS21440 43be61644758176bc6e0e851b480fabf 47 Pfam PF00468 Ribosomal protein L34 5 47 3.7E-18 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS21440 43be61644758176bc6e0e851b480fabf 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.243 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS21440 43be61644758176bc6e0e851b480fabf 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 45 1.0E-14 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS21440 43be61644758176bc6e0e851b480fabf 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 1.1E-16 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS21440 43be61644758176bc6e0e851b480fabf 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 167 3.8E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 Gene3D G3DSA:3.30.110.10 79 178 3.0E-31 T 28-03-2018 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 168 2.8E-60 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 SUPERFAMILY SSF54364 5 78 1.31E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 Gene3D G3DSA:3.10.20.80 2 78 7.1E-32 T 28-03-2018 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 SUPERFAMILY SSF55200 85 168 2.88E-29 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 75 1.8E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CP478_RS08985 a45ef1a0c680eacd4e7c9be7a7ec4365 201 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 29.337 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 Gene3D G3DSA:1.10.10.10 45 159 5.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 Pfam PF01047 MarR family 83 141 2.9E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 PRINTS PR00598 Bacterial regulatory protein MarR family signature 166 186 6.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 132 6.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 152 6.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 SUPERFAMILY SSF46785 51 190 9.87E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 Gene3D G3DSA:1.10.287.100 160 191 1.3E-5 T 28-03-2018 CP478_RS00235 645703ef2af5816673b8e56c44bc856c 208 SMART SM00347 76 176 4.8E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 SUPERFAMILY SSF55103 273 525 2.29E-32 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 Pfam PF02913 FAD linked oxidases, C-terminal domain 270 522 2.0E-48 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 Pfam PF01565 FAD binding domain 94 229 2.3E-32 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 Gene3D G3DSA:3.30.43.10 8 149 5.9E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 SUPERFAMILY SSF56176 73 270 7.48E-42 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 Gene3D G3DSA:1.10.45.10 486 524 1.1E-8 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CP478_RS17005 985008f7f0b76d53e1ed89643c20ebf2 527 Gene3D G3DSA:3.30.465.10 152 288 5.4E-26 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS00605 e91ce03f6cf03df573f78e03b6d9639f 249 Gene3D G3DSA:1.20.1540.10 34 205 8.8E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS00605 e91ce03f6cf03df573f78e03b6d9639f 249 SUPERFAMILY SSF144091 35 212 1.96E-43 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS00605 e91ce03f6cf03df573f78e03b6d9639f 249 Pfam PF01694 Rhomboid family 72 204 7.8E-34 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 14 174 7.0E-51 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 12 186 33.839 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 SUPERFAMILY SSF55811 12 175 8.53E-42 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 Pfam PF00293 NUDIX domain 39 170 3.8E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 Gene3D G3DSA:3.90.79.10 39 186 4.1E-26 T 28-03-2018 CP478_RS09520 bbc3f278648c31184334d5729ae96b66 203 PIRSF PIRSF018427 1 198 2.8E-58 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 PRINTS PR00123 ATP synthase A subunit signature 226 241 5.6E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 PRINTS PR00123 ATP synthase A subunit signature 179 201 5.6E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 PRINTS PR00123 ATP synthase A subunit signature 163 178 5.6E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 PRINTS PR00123 ATP synthase A subunit signature 90 106 5.6E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 SUPERFAMILY SSF81336 85 240 2.88E-35 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 Gene3D G3DSA:1.20.120.220 82 249 1.3E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 Hamap MF_01393 ATP synthase subunit a [atpB]. 13 246 13.729 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 Pfam PF00119 ATP synthase A chain 31 240 8.6E-49 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 ProSitePatterns PS00449 ATP synthase a subunit signature. 182 191 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07145 f8c3fcf1fe8e5da68d01ef9c7b54160e 250 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 36 242 1.2E-35 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS14095 ac0ec4f3f889aba710d1fa78187310a4 355 Pfam PF13515 Fusaric acid resistance protein-like 37 163 6.1E-13 T 28-03-2018 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 SUPERFAMILY SSF52922 562 699 2.57E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 SMART SM00861 375 557 5.9E-63 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Pfam PF02780 Transketolase, C-terminal domain 583 690 3.0E-12 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Gene3D G3DSA:3.40.50.970 373 565 2.0E-41 T 28-03-2018 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 1.9E-144 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Gene3D G3DSA:3.40.50.970 3 372 3.8E-85 T 28-03-2018 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 SUPERFAMILY SSF52518 16 343 1.65E-98 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 TIGRFAM TIGR00232 tktlase_bact: transketolase 26 696 2.3E-231 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Pfam PF02779 Transketolase, pyrimidine binding domain 374 555 2.1E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 Gene3D G3DSA:3.40.50.920 568 700 2.5E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CP478_RS07945 b3dea8153055d8a460e8e7ef36ad0c05 700 SUPERFAMILY SSF52518 353 558 2.26E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS10960 80e2cc08d9778cb113078406f085f9ba 143 SUPERFAMILY SSF46785 6 137 4.36E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10960 80e2cc08d9778cb113078406f085f9ba 143 Pfam PF12802 MarR family 33 86 3.8E-10 T 28-03-2018 CP478_RS10960 80e2cc08d9778cb113078406f085f9ba 143 Gene3D G3DSA:1.10.10.10 4 107 5.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10960 80e2cc08d9778cb113078406f085f9ba 143 Gene3D G3DSA:1.10.10.10 108 142 0.12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20775 1f98576b90869fd95a0370c09f5dd066 338 SUPERFAMILY SSF53474 44 327 3.21E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20775 1f98576b90869fd95a0370c09f5dd066 338 Pfam PF00756 Putative esterase 58 321 6.3E-78 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS20775 1f98576b90869fd95a0370c09f5dd066 338 Gene3D G3DSA:3.40.50.1820 42 327 3.5E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01965 2734f67c02d2e6a67f3b31ac165a5ace 403 SUPERFAMILY SSF53300 227 355 5.93E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS01965 2734f67c02d2e6a67f3b31ac165a5ace 403 PIRSF PIRSF010256 1 402 2.3E-124 T 28-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 CP478_RS01965 2734f67c02d2e6a67f3b31ac165a5ace 403 SMART SM00327 227 390 7.1E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS01965 2734f67c02d2e6a67f3b31ac165a5ace 403 Gene3D G3DSA:3.40.50.410 195 356 9.1E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS01965 2734f67c02d2e6a67f3b31ac165a5ace 403 Pfam PF05762 VWA domain containing CoxE-like protein 172 391 2.7E-70 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CP478_RS17620 a71f730f363e4a068a307c7fea3eb382 203 PIRSF PIRSF000709 1 179 8.2E-9 T 28-03-2018 CP478_RS17620 a71f730f363e4a068a307c7fea3eb382 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 191 5.4E-45 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS17620 a71f730f363e4a068a307c7fea3eb382 203 Gene3D G3DSA:3.40.50.1240 2 203 8.0E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS17620 a71f730f363e4a068a307c7fea3eb382 203 SUPERFAMILY SSF53254 7 197 9.69E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS17620 a71f730f363e4a068a307c7fea3eb382 203 SMART SM00855 7 154 1.5E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 Pfam PF00795 Carbon-nitrogen hydrolase 13 280 4.4E-16 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 Gene3D G3DSA:3.40.50.620 355 670 4.1E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 Pfam PF02540 NAD synthase 347 520 4.5E-23 T 28-03-2018 IPR022310 NAD/GMP synthase CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 SUPERFAMILY SSF52402 615 647 2.33E-59 T 28-03-2018 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 SUPERFAMILY SSF52402 324 574 2.33E-59 T 28-03-2018 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 SUPERFAMILY SSF56317 10 295 7.19E-49 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 PIRSF PIRSF006630 9 669 5.7E-193 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CP478_RS13325 c8aa886aecb0906adc99e90d684b3e43 679 Gene3D G3DSA:3.60.110.10 3 354 3.7E-80 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 16.925 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 101 2.2E-24 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 SUPERFAMILY SSF51344 4 85 3.01E-18 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 84 3.0E-32 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 3.2E-23 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07180 a37490ea09302ec2ed5de069e58030a0 121 Gene3D G3DSA:2.60.15.10 1 90 2.6E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS02945 3bd22b93013291ec75717e9c992e2f52 88 Pfam PF07362 Post-segregation antitoxin CcdA 19 61 4.5E-6 T 28-03-2018 IPR009956 Post-segregation antitoxin CcdA CP478_RS02945 3bd22b93013291ec75717e9c992e2f52 88 Gene3D G3DSA:1.10.1220.10 15 68 8.9E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS06680 1ad439b09c31f5f61d88916327207b9e 224 Pfam PF01596 O-methyltransferase 44 221 2.7E-25 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CP478_RS06680 1ad439b09c31f5f61d88916327207b9e 224 SUPERFAMILY SSF53335 50 223 1.89E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS06680 1ad439b09c31f5f61d88916327207b9e 224 Gene3D G3DSA:3.40.50.150 18 223 4.9E-31 T 28-03-2018 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 SMART SM00862 149 225 3.1E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 Gene3D G3DSA:3.40.50.2300 1 122 2.8E-34 T 28-03-2018 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 SMART SM00448 2 112 5.8E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 Gene3D G3DSA:1.10.10.10 123 227 9.5E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 SUPERFAMILY SSF46894 124 226 1.62E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 SUPERFAMILY SSF52172 2 119 1.99E-39 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS02620 cb9a265483d23961f83e407b8323b778 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 6.1E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 Pfam PF02634 FdhD/NarQ family 26 275 2.5E-81 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 275 3.0E-48 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 276 32.643 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 Gene3D G3DSA:3.10.20.10 28 123 4.0E-30 T 28-03-2018 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 PIRSF PIRSF015626 2 276 4.8E-83 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 Gene3D G3DSA:3.40.140.10 140 276 1.4E-53 T 28-03-2018 CP478_RS15840 240c6c64ee7270a6e6b88e4c06ff7de5 276 SUPERFAMILY SSF53927 7 275 1.47E-75 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 SUPERFAMILY SSF48264 41 427 1.28E-83 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 348 363 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 179 194 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 370 379 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 162 178 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 379 390 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 113 124 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 303 314 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 221 243 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 PRINTS PR00359 B-class P450 signature 320 347 1.4E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 Pfam PF00067 Cytochrome P450 304 393 2.4E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 Pfam PF00067 Cytochrome P450 109 291 2.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS12325 6bec5b5d474a16e9001698c227f6c1f1 428 Gene3D G3DSA:1.10.630.10 1 428 9.8E-76 T 28-03-2018 CP478_RS19800 4492e3d7875337c240bf54f8eca6788d 350 SUPERFAMILY SSF55486 13 349 1.39E-97 T 28-03-2018 CP478_RS19800 4492e3d7875337c240bf54f8eca6788d 350 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 13 349 4.5E-129 T 28-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated CP478_RS19800 4492e3d7875337c240bf54f8eca6788d 350 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 13 349 7.9E-119 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CP478_RS19800 4492e3d7875337c240bf54f8eca6788d 350 Pfam PF10103 Zincin-like metallopeptidase 13 346 1.5E-100 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CP478_RS20870 2b5cdd0fcaa4d1f4c4ef022a1bd6b323 237 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 235 3.9E-59 T 28-03-2018 IPR021315 Glycolipid exporter Gap/Sap CP478_RS03485 65c549e2beae8f3e98d84adcd55b2aa5 286 Gene3D G3DSA:3.40.50.150 2 286 1.5E-56 T 28-03-2018 CP478_RS03485 65c549e2beae8f3e98d84adcd55b2aa5 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 282 3.8E-116 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03485 65c549e2beae8f3e98d84adcd55b2aa5 286 PIRSF PIRSF003085 5 286 1.6E-94 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS03485 65c549e2beae8f3e98d84adcd55b2aa5 286 SUPERFAMILY SSF53335 12 286 9.8E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 Gene3D G3DSA:3.20.20.70 4 365 5.9E-131 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 PIRSF PIRSF036915 1 373 4.2E-182 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 Hamap MF_00493 Transaldolase [tal]. 1 373 164.118 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 TIGRFAM TIGR00876 tal_mycobact: transaldolase 14 363 1.0E-209 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 SUPERFAMILY SSF51569 9 362 6.47E-80 T 28-03-2018 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 ProSitePatterns PS00958 Transaldolase active site. 140 157 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 ProSitePatterns PS01054 Transaldolase signature 1. 44 52 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CP478_RS07940 0d6c7a2dcda03b7f7105422c400d5c33 373 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 18 363 1.3E-85 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CP478_RS00765 04c0709d0361fc3453a01603c81cf836 136 SUPERFAMILY SSF54427 9 122 4.96E-20 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS00765 04c0709d0361fc3453a01603c81cf836 136 Gene3D G3DSA:3.10.450.50 8 133 6.1E-13 T 28-03-2018 CP478_RS00765 04c0709d0361fc3453a01603c81cf836 136 Pfam PF12680 SnoaL-like domain 20 111 2.8E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS20050 59b2c5edc86d34b2e62291fd49820814 273 Gene3D G3DSA:3.90.79.10 55 246 9.0E-33 T 28-03-2018 CP478_RS20050 59b2c5edc86d34b2e62291fd49820814 273 SUPERFAMILY SSF55811 97 238 8.94E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS20050 59b2c5edc86d34b2e62291fd49820814 273 ProSitePatterns PS01293 Nudix CoA signature. 102 122 - T 28-03-2018 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918 CP478_RS20050 59b2c5edc86d34b2e62291fd49820814 273 Pfam PF00293 NUDIX domain 99 200 2.2E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS10170 dc13953753de0762ee1bdb01b2673ff7 129 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 126 1.3E-31 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS10170 dc13953753de0762ee1bdb01b2673ff7 129 SUPERFAMILY SSF50475 29 109 6.14E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS10170 dc13953753de0762ee1bdb01b2673ff7 129 Pfam PF04075 F420H(2)-dependent quinone reductase 8 128 3.2E-39 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS10170 dc13953753de0762ee1bdb01b2673ff7 129 Gene3D G3DSA:2.30.110.10 2 117 1.2E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 Pfam PF01343 Peptidase family S49 403 554 1.7E-51 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 Pfam PF01343 Peptidase family S49 129 282 2.2E-47 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 SUPERFAMILY SSF52096 84 177 1.16E-23 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 SUPERFAMILY SSF52096 210 270 1.16E-23 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 Gene3D G3DSA:3.90.226.10 56 295 2.1E-21 T 28-03-2018 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 82 600 1.4E-107 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 SUPERFAMILY SSF52096 326 451 9.04E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 SUPERFAMILY SSF52096 480 540 9.04E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 PIRSF PIRSF001217 3 623 6.2E-175 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 332 552 2.3E-51 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CP478_RS03920 c3ae78da25c94dbea021289f441bea55 623 Gene3D G3DSA:3.90.226.10 324 587 1.1E-47 T 28-03-2018 CP478_RS04215 d7a2a17285e461f14fce4c36f471a632 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04215 d7a2a17285e461f14fce4c36f471a632 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04215 d7a2a17285e461f14fce4c36f471a632 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04215 d7a2a17285e461f14fce4c36f471a632 207 SUPERFAMILY SSF46689 9 79 3.8E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS04215 d7a2a17285e461f14fce4c36f471a632 207 Gene3D G3DSA:1.10.357.10 3 204 1.1E-21 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 PRINTS PR01228 Eggshell protein signature 278 288 1.7E-7 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 PRINTS PR01228 Eggshell protein signature 313 331 1.7E-7 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 PRINTS PR01228 Eggshell protein signature 182 193 1.7E-7 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 PRINTS PR01228 Eggshell protein signature 251 266 1.7E-7 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 Pfam PF00934 PE family 1 93 4.8E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 SUPERFAMILY SSF140459 8 84 4.18E-24 T 28-03-2018 CP478_RS05860 4dbd7fff4a74d70c579007a2c9c652af 463 Gene3D G3DSA:1.10.287.1060 1 99 5.8E-4 T 28-03-2018 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 181 324 4.5E-60 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 SUPERFAMILY SSF51735 1 180 2.02E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 Gene3D G3DSA:1.10.1040.10 53 328 1.5E-110 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 PIRSF PIRSF000116 201 330 1.6E-16 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 PIRSF PIRSF000116 2 203 2.5E-40 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 12 324 1.6E-119 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 12 175 3.8E-69 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 SUPERFAMILY SSF48179 181 326 4.25E-64 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS16420 b63e40e22f1a9aab3b287974f691e30d 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 326 43.751 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 Gene3D G3DSA:1.10.10.60 1 58 7.0E-19 T 28-03-2018 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 6.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 Gene3D G3DSA:1.10.357.10 59 197 1.2E-14 T 28-03-2018 CP478_RS20920 2eb41f291c7758054589778a809d3d67 209 SUPERFAMILY SSF46689 2 81 1.23E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS07820 60abf0a4f3709090e9ac6ddf25a0e0af 528 Gene3D G3DSA:3.40.50.1820 26 321 6.4E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07820 60abf0a4f3709090e9ac6ddf25a0e0af 528 SUPERFAMILY SSF140459 8 84 3.4E-24 T 28-03-2018 CP478_RS07820 60abf0a4f3709090e9ac6ddf25a0e0af 528 Pfam PF08237 PE-PPE domain 149 369 1.9E-81 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS07820 60abf0a4f3709090e9ac6ddf25a0e0af 528 Pfam PF00934 PE family 1 93 3.2E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS07820 60abf0a4f3709090e9ac6ddf25a0e0af 528 SUPERFAMILY SSF53474 118 248 1.08E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07595 c4d2dc16a3e394bbbe985fd5592d913b 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 38 81 5.0E-18 T 28-03-2018 CP478_RS07595 c4d2dc16a3e394bbbe985fd5592d913b 102 SUPERFAMILY SSF140459 7 73 1.52E-13 T 28-03-2018 CP478_RS07595 c4d2dc16a3e394bbbe985fd5592d913b 102 Pfam PF00934 PE family 3 91 5.7E-21 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 SUPERFAMILY SSF140459 8 84 7.59E-25 T 28-03-2018 CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 PRINTS PR01228 Eggshell protein signature 195 210 9.0E-6 T 28-03-2018 CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 PRINTS PR01228 Eggshell protein signature 250 268 9.0E-6 T 28-03-2018 CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 PRINTS PR01228 Eggshell protein signature 226 236 9.0E-6 T 28-03-2018 CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 PRINTS PR01228 Eggshell protein signature 98 114 9.0E-6 T 28-03-2018 CP478_RS13075 4c1e1b656c9073f5013e52a6025ea8bd 361 Pfam PF00934 PE family 1 93 7.0E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS08160 aa1d3ab8cc0f06bdc25788ca9b3c74e5 76 Gene3D G3DSA:3.20.20.240 2 65 5.7E-6 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08160 aa1d3ab8cc0f06bdc25788ca9b3c74e5 76 Pfam PF01642 Methylmalonyl-CoA mutase 5 49 4.6E-5 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 SUPERFAMILY SSF53597 1 158 4.08E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 PRINTS PR00070 Dihydrofolate reductase signature 90 104 2.0E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 PRINTS PR00070 Dihydrofolate reductase signature 27 35 2.0E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 PRINTS PR00070 Dihydrofolate reductase signature 13 23 2.0E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 PRINTS PR00070 Dihydrofolate reductase signature 40 51 2.0E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 Gene3D G3DSA:3.40.430.10 37 159 7.7E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 Gene3D G3DSA:3.40.430.10 1 36 2.1E-11 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 PIRSF PIRSF000194 1 159 2.5E-46 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS15135 1a69c97ef97b2b93b60dbdde6dbd3561 159 Pfam PF00186 Dihydrofolate reductase 1 156 1.2E-44 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CP478_RS14365 0e7e09e3dae9023ac129a753d84a3486 273 SUPERFAMILY SSF53335 17 256 2.34E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14365 0e7e09e3dae9023ac129a753d84a3486 273 Pfam PF08241 Methyltransferase domain 59 153 2.8E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS14365 0e7e09e3dae9023ac129a753d84a3486 273 Gene3D G3DSA:3.40.50.150 21 223 3.0E-22 T 28-03-2018 CP478_RS20505 94cf73aae14e06eea33759a8220d26c7 323 Gene3D G3DSA:3.40.50.720 2 183 6.1E-25 T 28-03-2018 CP478_RS20505 94cf73aae14e06eea33759a8220d26c7 323 SUPERFAMILY SSF48179 179 279 1.36E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS20505 94cf73aae14e06eea33759a8220d26c7 323 SUPERFAMILY SSF51735 10 173 3.06E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS20505 94cf73aae14e06eea33759a8220d26c7 323 Gene3D G3DSA:1.10.3660.10 185 309 9.1E-11 T 28-03-2018 CP478_RS20505 94cf73aae14e06eea33759a8220d26c7 323 Pfam PF02153 Prephenate dehydrogenase 31 262 3.3E-40 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CP478_RS07140 64909a002c5aa56be9f1e63c9bb839b2 161 Pfam PF03899 ATP synthase I chain 21 114 2.5E-10 T 28-03-2018 IPR005598 ATP synthase protein I CP478_RS21200 ff82af944b0a6d58c81a4d5e27eddb6f 280 Gene3D G3DSA:1.10.287.1060 97 182 0.067 T 28-03-2018 CP478_RS21200 ff82af944b0a6d58c81a4d5e27eddb6f 280 Gene3D G3DSA:1.10.287.1060 10 96 0.091 T 28-03-2018 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 525 1.9E-160 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 Pfam PF00361 Proton-conducting membrane transporter 160 459 2.1E-65 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 197 221 1.6E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 417 443 1.6E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 277 301 1.6E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 365 384 1.6E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17285 01b6e8fecd4fbab73c4b5ee2c99d76f5 553 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 185 1.6E-30 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17065 e21467c8d237b49ef621971735cc97bf 100 Pfam PF07210 Protein of unknown function (DUF1416) 2 99 2.7E-42 T 28-03-2018 IPR010814 Protein of unknown function DUF1416 CP478_RS17065 e21467c8d237b49ef621971735cc97bf 100 SUPERFAMILY SSF49464 23 75 4.71E-8 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CP478_RS17065 e21467c8d237b49ef621971735cc97bf 100 Gene3D G3DSA:2.60.40.10 18 100 1.2E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS04420 e21467c8d237b49ef621971735cc97bf 100 Pfam PF07210 Protein of unknown function (DUF1416) 2 99 2.7E-42 T 28-03-2018 IPR010814 Protein of unknown function DUF1416 CP478_RS04420 e21467c8d237b49ef621971735cc97bf 100 SUPERFAMILY SSF49464 23 75 4.71E-8 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CP478_RS04420 e21467c8d237b49ef621971735cc97bf 100 Gene3D G3DSA:2.60.40.10 18 100 1.2E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS02385 ed114f036d408762850a9414fdf8a1c1 439 Gene3D G3DSA:3.90.660.20 39 394 3.6E-43 T 28-03-2018 CP478_RS02385 ed114f036d408762850a9414fdf8a1c1 439 Pfam PF01593 Flavin containing amine oxidoreductase 16 423 2.1E-37 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CP478_RS02385 ed114f036d408762850a9414fdf8a1c1 439 SUPERFAMILY SSF51905 392 423 2.27E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02385 ed114f036d408762850a9414fdf8a1c1 439 SUPERFAMILY SSF51905 9 314 2.27E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS09735 02020b1ae7614764452903c91633e4e6 99 Gene3D G3DSA:1.10.287.1060 1 99 2.3E-4 T 28-03-2018 CP478_RS09735 02020b1ae7614764452903c91633e4e6 99 Pfam PF00934 PE family 1 93 1.1E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09735 02020b1ae7614764452903c91633e4e6 99 SUPERFAMILY SSF140459 8 83 2.88E-26 T 28-03-2018 CP478_RS01180 f04b268af0a680980ff903aec3c0885b 442 Pfam PF00174 Oxidoreductase molybdopterin binding domain 310 441 1.0E-18 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CP478_RS01180 f04b268af0a680980ff903aec3c0885b 442 Gene3D G3DSA:1.20.950.20 85 214 2.7E-5 T 28-03-2018 CP478_RS01180 f04b268af0a680980ff903aec3c0885b 442 SUPERFAMILY SSF56524 279 441 3.79E-29 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CP478_RS01180 f04b268af0a680980ff903aec3c0885b 442 Gene3D G3DSA:3.90.420.10 273 442 6.6E-30 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CP478_RS06795 f9e9cadefb58f48d9b4cc53a424de114 86 Gene3D G3DSA:1.10.1220.10 1 39 3.3E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS01070 c1071408d0e2bfef1d4644ff22fe006c 194 SUPERFAMILY SSF48498 74 185 3.56E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS01070 c1071408d0e2bfef1d4644ff22fe006c 194 Gene3D G3DSA:1.10.357.10 50 186 2.0E-19 T 28-03-2018 CP478_RS01070 c1071408d0e2bfef1d4644ff22fe006c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 52 3.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01070 c1071408d0e2bfef1d4644ff22fe006c 194 Gene3D G3DSA:1.10.10.60 2 49 2.5E-8 T 28-03-2018 CP478_RS01070 c1071408d0e2bfef1d4644ff22fe006c 194 SUPERFAMILY SSF46689 4 70 4.67E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16830 636f1e2b40386f8c1c97469e072a4413 158 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 154 2.0E-23 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS16830 636f1e2b40386f8c1c97469e072a4413 158 Gene3D G3DSA:3.30.530.20 8 158 2.1E-26 T 28-03-2018 IPR023393 START-like domain CP478_RS16830 636f1e2b40386f8c1c97469e072a4413 158 SUPERFAMILY SSF55961 11 157 1.0E-25 T 28-03-2018 CP478_RS05255 a64145634851d4a8cfb2eeb08471511e 224 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 28 170 7.3E-32 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CP478_RS19760 9e18e8d578692da187c0526dcc0e4362 395 Pfam PF00296 Luciferase-like monooxygenase 6 317 2.7E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS19760 9e18e8d578692da187c0526dcc0e4362 395 Gene3D G3DSA:3.20.20.30 12 389 2.8E-65 T 28-03-2018 CP478_RS19760 9e18e8d578692da187c0526dcc0e4362 395 SUPERFAMILY SSF51679 5 351 1.65E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 Pfam PF05199 GMC oxidoreductase 468 525 8.7E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 39 4.8E-5 T 28-03-2018 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 SUPERFAMILY SSF51905 470 531 4.61E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 SUPERFAMILY SSF51905 1 161 4.61E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 SUPERFAMILY SSF51905 189 304 4.61E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18660 e09e56e46ef0de9b9f67bf7d1ffefdac 578 Gene3D G3DSA:3.50.50.60 1 548 4.0E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 SUPERFAMILY SSF54675 20 147 3.03E-37 T 28-03-2018 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 21 436 1.7E-143 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 Gene3D G3DSA:3.20.140.10 7 386 2.7E-96 T 28-03-2018 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 PIRSF PIRSF000484 12 442 3.4E-108 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 149 325 3.4E-6 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CP478_RS07295 1832ccd98fd914dd127b148c1bec323c 448 SUPERFAMILY SSF51690 149 442 5.3E-79 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CP478_RS19690 b70211072435396b96137dc266d4ed97 188 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 139 5.5E-40 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CP478_RS19690 b70211072435396b96137dc266d4ed97 188 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CP478_RS19690 b70211072435396b96137dc266d4ed97 188 Gene3D G3DSA:3.30.70.560 1 181 9.2E-43 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CP478_RS19690 b70211072435396b96137dc266d4ed97 188 SUPERFAMILY SSF55083 1 148 4.05E-35 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CP478_RS19690 b70211072435396b96137dc266d4ed97 188 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 139 2.5E-29 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CP478_RS15685 0c501a29a769b02a199c26be8b78955f 404 SMART SM00228 129 203 7.1E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS15685 0c501a29a769b02a199c26be8b78955f 404 Pfam PF02163 Peptidase family M50 10 371 2.3E-52 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CP478_RS15685 0c501a29a769b02a199c26be8b78955f 404 SUPERFAMILY SSF50156 102 210 1.17E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS15685 0c501a29a769b02a199c26be8b78955f 404 Gene3D G3DSA:2.30.42.10 29 208 4.7E-13 T 28-03-2018 CP478_RS10730 01ad7b1eab266526ae213913c04dcf71 437 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 299 1.4E-82 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10730 01ad7b1eab266526ae213913c04dcf71 437 Pfam PF02470 MlaD protein 43 116 5.3E-15 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 SUPERFAMILY SSF56024 378 554 1.85E-56 T 28-03-2018 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Pfam PF13089 Polyphosphate kinase N-terminal domain 53 159 4.0E-36 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Hamap MF_00347 Polyphosphate kinase [ppk]. 51 741 29.394 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 SUPERFAMILY SSF56024 558 740 6.5E-58 T 28-03-2018 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Pfam PF02503 Polyphosphate kinase middle domain 168 376 1.4E-68 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Pfam PF13090 Polyphosphate kinase C-terminal domain 387 736 1.8E-144 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Gene3D G3DSA:1.20.58.310 55 157 7.6E-37 T 28-03-2018 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 52 737 4.8E-242 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Gene3D G3DSA:3.30.870.10 371 557 1.1E-19 T 28-03-2018 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 PIRSF PIRSF015589 34 742 1.8E-267 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Gene3D G3DSA:3.30.1840.10 158 361 4.7E-74 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 SUPERFAMILY SSF140356 50 154 6.93E-37 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 SUPERFAMILY SSF143724 156 366 6.87E-65 T 28-03-2018 CP478_RS16315 61b6f0084e291d0f735a6102923ebefb 742 Gene3D G3DSA:3.30.870.10 558 742 2.1E-38 T 28-03-2018 CP478_RS10340 d4d95b73ff86dc3bb5845b1e24a3d443 343 SUPERFAMILY SSF52949 149 336 4.21E-44 T 28-03-2018 CP478_RS10340 d4d95b73ff86dc3bb5845b1e24a3d443 343 Gene3D G3DSA:3.40.220.10 138 337 4.3E-44 T 28-03-2018 CP478_RS10340 d4d95b73ff86dc3bb5845b1e24a3d443 343 SMART SM00506 175 302 1.8E-44 T 28-03-2018 IPR002589 Macro domain CP478_RS10340 d4d95b73ff86dc3bb5845b1e24a3d443 343 Pfam PF01661 Macro domain 193 302 1.0E-26 T 28-03-2018 IPR002589 Macro domain CP478_RS14000 cdd5d2f11a17abbd1516101636ef7781 417 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 51 417 27.107 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CP478_RS14000 cdd5d2f11a17abbd1516101636ef7781 417 Pfam PF02618 YceG-like family 86 405 8.4E-59 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CP478_RS14000 cdd5d2f11a17abbd1516101636ef7781 417 Gene3D G3DSA:3.30.160.60 379 410 2.2E-7 T 28-03-2018 CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 SUPERFAMILY SSF55073 291 456 1.73E-38 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 SUPERFAMILY SSF53474 8 283 2.76E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 296 445 1.4E-13 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 SMART SM00044 276 437 2.4E-4 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 Gene3D G3DSA:3.40.50.1820 16 285 2.2E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 Pfam PF00561 alpha/beta hydrolase fold 63 146 4.6E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS10345 df0099a27d87b1ef91728d74c3ca8eea 462 Gene3D G3DSA:3.30.70.1230 289 462 6.1E-35 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS06940 62e812a3f4108212a8806597506ecdcf 232 Gene3D G3DSA:3.90.70.10 50 232 1.2E-14 T 28-03-2018 CP478_RS06940 62e812a3f4108212a8806597506ecdcf 232 Pfam PF13529 Peptidase_C39 like family 47 202 1.4E-8 T 28-03-2018 CP478_RS06940 62e812a3f4108212a8806597506ecdcf 232 ProDom PD109700 PRECURSOR SIGNAL MB1299C RV1268C/MT1306 36 232 4.0E-105 T 28-03-2018 CP478_RS06940 62e812a3f4108212a8806597506ecdcf 232 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 181 191 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CP478_RS13385 59c6088f9fbb11d1594a2bbcdeb82dc5 419 Gene3D G3DSA:3.40.50.720 3 162 2.4E-23 T 28-03-2018 CP478_RS13385 59c6088f9fbb11d1594a2bbcdeb82dc5 419 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 10 137 5.1E-13 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CP478_RS13385 59c6088f9fbb11d1594a2bbcdeb82dc5 419 SUPERFAMILY SSF51735 10 165 3.71E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 PIRSF PIRSF000443 3 375 6.7E-108 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 9 370 45.75 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 SUPERFAMILY SSF53474 19 368 2.37E-85 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 Pfam PF00561 alpha/beta hydrolase fold 52 356 2.0E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 Gene3D G3DSA:3.40.50.1820 31 377 3.8E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18295 af1bf566ed5f06b7515a4e2d774daf4f 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 23 368 1.3E-130 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Pfam PF00027 Cyclic nucleotide-binding domain 534 613 9.3E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Pfam PF01734 Patatin-like phospholipase 790 946 3.6E-20 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 578 595 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 SUPERFAMILY SSF103473 261 467 2.88E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 SUPERFAMILY SSF103473 17 209 2.88E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 6.2E-9 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 6.2E-9 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 6.2E-9 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 SMART SM00100 515 628 1.1E-25 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Gene3D G3DSA:1.20.1250.20 14 216 2.2E-32 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Gene3D G3DSA:1.20.1250.20 273 476 1.3E-19 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 793 825 - T 28-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 SUPERFAMILY SSF52151 786 1044 4.45E-43 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 434 5.6E-71 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Gene3D G3DSA:2.60.120.10 508 633 2.2E-28 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Pfam PF07690 Major Facilitator Superfamily 31 340 1.0E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 Gene3D G3DSA:3.40.1090.10 779 951 6.0E-33 T 28-03-2018 CP478_RS17765 2460f3c37ea31149975800077b9af131 1048 SUPERFAMILY SSF51206 509 629 2.88E-27 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS19765 284f149b74f843b00d67b80040fa43c6 94 SUPERFAMILY SSF140453 2 93 6.54E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19765 284f149b74f843b00d67b80040fa43c6 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 4.1E-12 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19765 284f149b74f843b00d67b80040fa43c6 94 Gene3D G3DSA:1.10.287.1060 1 94 5.6E-11 T 28-03-2018 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 78 86 1.6E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 120 135 1.6E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 158 174 1.6E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 Pfam PF01252 Signal peptidase (SPase) II 40 178 4.0E-30 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 31 183 15.301 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 TIGRFAM TIGR00077 lspA: signal peptidase II 33 178 1.8E-27 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS08435 4cc870dc4fdc33a069b22884938942cb 202 ProSitePatterns PS00855 Signal peptidases II signature. 123 135 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CP478_RS00755 12fe69e896c8eedfc0356e92479e912e 340 Gene3D G3DSA:3.40.50.720 6 334 3.0E-48 T 28-03-2018 CP478_RS00755 12fe69e896c8eedfc0356e92479e912e 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 234 2.0E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS00755 12fe69e896c8eedfc0356e92479e912e 340 SUPERFAMILY SSF51735 6 327 8.12E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 SUPERFAMILY SSF50715 8 188 6.28E-46 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 9 181 9.4E-60 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 Pfam PF01386 Ribosomal L25p family 9 95 6.7E-23 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 181 5.7E-16 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 Gene3D G3DSA:2.40.240.10 6 97 3.9E-28 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 12 96 3.0E-34 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 Gene3D G3DSA:2.170.120.20 102 187 1.4E-17 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CP478_RS05555 5acb5f3cc355af335198cad9a8facfcd 215 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 7 183 23.737 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CP478_RS04295 e2888b8a88788294053c508cb9ba8328 242 SUPERFAMILY SSF54001 25 162 5.89E-18 T 28-03-2018 CP478_RS04295 e2888b8a88788294053c508cb9ba8328 242 SMART SM00460 76 154 2.1E-19 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS04295 e2888b8a88788294053c508cb9ba8328 242 Pfam PF01841 Transglutaminase-like superfamily 29 152 1.7E-20 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14880 88439980f0def2368f520b9acda666b3 341 SUPERFAMILY SSF53474 16 294 4.54E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14880 88439980f0def2368f520b9acda666b3 341 Gene3D G3DSA:3.40.50.1820 8 308 2.6E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00412 Epoxide hydrolase signature 63 78 1.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00412 Epoxide hydrolase signature 237 253 1.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00412 Epoxide hydrolase signature 270 292 1.3E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 5.5E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 5.5E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 5.5E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14880 88439980f0def2368f520b9acda666b3 341 Pfam PF12697 Alpha/beta hydrolase family 40 287 1.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 Gene3D G3DSA:3.10.290.10 3 70 1.7E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 Gene3D G3DSA:3.30.2350.10 80 308 1.1E-60 T 28-03-2018 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 SMART SM00363 15 72 4.3E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 SUPERFAMILY SSF55174 14 63 1.48E-5 T 28-03-2018 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 305 5.9E-90 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 Pfam PF00849 RNA pseudouridylate synthase 90 243 4.9E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS08440 f054f1d388478659ded3fa7aa529b803 308 SUPERFAMILY SSF55120 75 305 1.49E-65 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 SUPERFAMILY SSF48498 81 199 2.46E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 Pfam PF08360 QacR-like protein, C-terminal region 81 195 2.3E-4 T 28-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 8.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 SUPERFAMILY SSF46689 6 76 7.7E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 Gene3D G3DSA:1.10.357.10 68 204 3.0E-17 T 28-03-2018 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 Gene3D G3DSA:1.10.10.60 2 67 5.8E-16 T 28-03-2018 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00870 54a1522179128ee76c50f5c2f1593e22 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 Gene3D G3DSA:1.10.1040.10 176 280 4.8E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 SUPERFAMILY SSF51735 8 172 1.04E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 PIRSF PIRSF000105 4 302 4.2E-75 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 177 275 1.2E-20 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 Gene3D G3DSA:3.40.50.720 2 174 1.8E-41 T 28-03-2018 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 174 4.8E-47 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CP478_RS09355 1796b7ee3e53e9933aab2a529ee56506 304 SUPERFAMILY SSF48179 176 282 5.53E-22 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 8.4E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Pfam PF00501 AMP-binding enzyme 14 412 3.1E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 SUPERFAMILY SSF56801 5 506 4.71E-142 T 28-03-2018 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Gene3D G3DSA:2.30.38.10 333 406 8.3E-19 T 28-03-2018 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Gene3D G3DSA:3.40.50.980 3 179 8.6E-39 T 28-03-2018 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Gene3D G3DSA:3.30.300.30 408 507 1.5E-25 T 28-03-2018 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 Gene3D G3DSA:3.40.50.980 180 332 5.8E-43 T 28-03-2018 CP478_RS19460 ebdb674242fde74464c05c47f66cd722 507 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS18140 ca66d0d0171b3c95369f13d9b09053eb 308 Pfam PF00561 alpha/beta hydrolase fold 45 288 2.2E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS18140 ca66d0d0171b3c95369f13d9b09053eb 308 SUPERFAMILY SSF53474 20 297 1.54E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18140 ca66d0d0171b3c95369f13d9b09053eb 308 Gene3D G3DSA:3.40.50.1820 12 299 4.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 Gene3D G3DSA:3.40.190.10 185 319 1.4E-22 T 28-03-2018 CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 Gene3D G3DSA:3.10.105.10 320 600 1.8E-36 T 28-03-2018 CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 Gene3D G3DSA:3.90.76.10 90 184 1.9E-14 T 28-03-2018 CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 108 483 5.0E-32 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 SUPERFAMILY SSF53850 415 507 1.33E-54 T 28-03-2018 CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 SUPERFAMILY SSF53850 551 616 1.33E-54 T 28-03-2018 CP478_RS06405 08bbcad9c6fab2664f89a35423edf743 635 SUPERFAMILY SSF53850 49 387 1.33E-54 T 28-03-2018 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 PIRSF PIRSF006402 1 671 1.9E-185 T 28-03-2018 IPR024705 Spermatogenesis-associated protein 20 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Pfam PF03190 Protein of unknown function, DUF255 9 164 3.2E-67 T 28-03-2018 IPR004879 Domain of unknown function DUF255 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 SUPERFAMILY SSF48208 194 533 3.74E-63 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 SUPERFAMILY SSF52833 9 139 1.09E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Gene3D G3DSA:1.50.10.10 362 589 2.7E-24 T 28-03-2018 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 232 309 0.1 T 28-03-2018 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 476 519 0.44 T 28-03-2018 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Gene3D G3DSA:3.40.30.10 7 171 1.8E-27 T 28-03-2018 CP478_RS05940 160d0e1fe9f325387478b363095af58a 673 Gene3D G3DSA:1.50.10.10 218 361 9.1E-26 T 28-03-2018 CP478_RS16615 3581a8cff4a1c3b951d7a82043aa6a1e 358 Gene3D G3DSA:3.40.50.150 49 224 6.5E-19 T 28-03-2018 CP478_RS16615 3581a8cff4a1c3b951d7a82043aa6a1e 358 SUPERFAMILY SSF53335 49 173 3.75E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15330 269eae37331a0dae7818f200e24eb511 118 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 113 7.9E-28 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS15330 269eae37331a0dae7818f200e24eb511 118 Gene3D G3DSA:2.30.30.110 1 118 9.1E-29 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS15330 269eae37331a0dae7818f200e24eb511 118 SUPERFAMILY SSF50118 1 116 4.58E-30 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS15330 269eae37331a0dae7818f200e24eb511 118 PIRSF PIRSF033490 1 116 3.3E-43 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 SUPERFAMILY SSF52540 61 269 2.62E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 Pfam PF13541 Subunit ChlI of Mg-chelatase 366 427 1.7E-7 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 41.18 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 Gene3D G3DSA:3.30.230.10 288 453 1.8E-22 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 Gene3D G3DSA:3.40.50.300 70 278 3.2E-43 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 445 3.4E-143 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 SMART SM00382 87 243 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 SUPERFAMILY SSF54211 254 268 1.63E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 SUPERFAMILY SSF54211 302 453 1.63E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 Pfam PF13481 AAA domain 75 221 1.1E-16 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 173 197 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 10 34 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 321 344 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 247 273 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 79 107 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 212 240 3.0E-78 T 28-03-2018 CP478_RS19590 ac4c0055b9188b37db71f7e101c1822a 480 PRINTS PR01874 DNA repair protein radA signature 121 138 3.0E-78 T 28-03-2018 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 157 32.041 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 SUPERFAMILY SSF69765 5 157 2.35E-51 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 Pfam PF02542 YgbB family 6 155 2.3E-48 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 Gene3D G3DSA:3.30.1330.50 1 159 3.3E-59 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS19570 e3111edc71377261b72359c30b86b18d 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 156 2.4E-56 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 4 310 58.757 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Gene3D G3DSA:1.10.443.10 120 304 3.7E-49 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 98 2.8E-25 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Gene3D G3DSA:1.10.150.130 6 119 6.3E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 310 55.941 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 10 310 2.3E-104 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 SUPERFAMILY SSF56349 7 302 4.71E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS09280 d60dfb4bbc7c2f13af72192a3d767afc 311 Pfam PF00589 Phage integrase family 120 294 4.1E-46 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 588 50.461 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 289 439 4.2E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 246 5.2E-55 T 28-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 Gene3D G3DSA:1.20.120.330 20 170 1.3E-5 T 28-03-2018 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 587 1.3E-265 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 ProSitePatterns PS00674 AAA-protein family signature. 409 427 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 SMART SM00382 285 441 7.4E-22 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 Gene3D G3DSA:3.40.50.300 227 456 2.6E-55 T 28-03-2018 CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 SUPERFAMILY SSF52540 497 552 5.72E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11510 7d2d727c083f8080f30645aacde1c1fb 609 SUPERFAMILY SSF52540 247 456 5.72E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 Gene3D G3DSA:1.10.10.410 446 505 2.4E-14 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 173 187 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 24 507 35.299 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 SUPERFAMILY SSF89095 359 504 3.79E-21 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 SUPERFAMILY SSF55931 27 328 2.62E-109 T 28-03-2018 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 25 504 5.1E-139 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 SMART SM00845 359 506 9.8E-50 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 Pfam PF02934 GatB/GatE catalytic domain 28 321 1.8E-104 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CP478_RS16460 94251bca642b19867c8c1e615cdc9a70 509 Pfam PF02637 GatB domain 361 504 4.2E-36 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 Pfam PF00326 Prolyl oligopeptidase family 484 700 1.5E-63 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 Gene3D G3DSA:2.130.10.120 78 421 1.4E-62 T 28-03-2018 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 Gene3D G3DSA:3.40.50.1820 422 701 4.7E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04245 77a72143a1d58042cddee954c9076170 719 SUPERFAMILY SSF50993 7 434 1.73E-96 T 28-03-2018 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 SUPERFAMILY SSF53474 438 683 1.93E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 523 542 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 630 652 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 495 519 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 553 573 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 612 627 1.3E-56 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS04245 77a72143a1d58042cddee954c9076170 719 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 10 428 2.9E-119 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 PIRSF PIRSF006078 1 153 6.5E-40 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 PIRSF PIRSF006078 152 352 4.7E-51 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 SUPERFAMILY SSF110738 1 348 1.27E-86 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 Pfam PF02595 Glycerate kinase family 3 151 3.8E-41 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 Pfam PF02595 Glycerate kinase family 155 348 2.5E-52 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 Gene3D G3DSA:3.90.1510.10 42 155 1.5E-31 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CP478_RS11985 8ba75048578ff3c24d5a6a776537cb72 358 Gene3D G3DSA:3.90.1510.10 156 252 2.3E-24 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CP478_RS15420 72321d3e6b8464a367efc8ce3d3c3cad 375 Pfam PF03787 RAMP superfamily 11 263 6.3E-10 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CP478_RS15420 72321d3e6b8464a367efc8ce3d3c3cad 375 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 11 369 3.3E-112 T 28-03-2018 IPR010173 CRISPR-associated protein, TM1807 CP478_RS00140 017aeec160db8186367ddfe01da9431b 281 SUPERFAMILY SSF54001 163 272 1.28E-34 T 28-03-2018 CP478_RS00140 017aeec160db8186367ddfe01da9431b 281 Gene3D G3DSA:3.90.1720.10 165 280 2.3E-31 T 28-03-2018 CP478_RS00140 017aeec160db8186367ddfe01da9431b 281 Pfam PF00877 NlpC/P60 family 182 271 4.7E-21 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 PIRSF PIRSF001434 11 406 2.2E-113 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 21 406 51.168 T 28-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 20 405 1.3E-204 T 28-03-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 Gene3D G3DSA:3.90.1150.10 270 406 5.5E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 21 405 5.1E-132 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 Gene3D G3DSA:3.40.640.10 17 269 1.5E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS02080 3479786f1afe52abed74e98cd8c8b9fb 406 SUPERFAMILY SSF53383 39 405 7.51E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS19790 112a9469d406f37fa314b24a1b369892 216 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 40 210 4.5E-67 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CP478_RS19790 112a9469d406f37fa314b24a1b369892 216 Pfam PF00156 Phosphoribosyl transferase domain 64 197 2.3E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS19790 112a9469d406f37fa314b24a1b369892 216 SUPERFAMILY SSF53271 36 212 3.02E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS19790 112a9469d406f37fa314b24a1b369892 216 Gene3D G3DSA:3.40.50.2020 18 216 8.6E-41 T 28-03-2018 CP478_RS20075 a7fd4fa4e457669a9138b56d16502432 264 Pfam PF00753 Metallo-beta-lactamase superfamily 35 193 2.4E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20075 a7fd4fa4e457669a9138b56d16502432 264 SUPERFAMILY SSF56281 16 263 2.3E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20075 a7fd4fa4e457669a9138b56d16502432 264 SMART SM00849 38 193 6.4E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS20075 a7fd4fa4e457669a9138b56d16502432 264 Gene3D G3DSA:3.60.15.10 37 258 1.9E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02490 98927260a3483192bdead19386b22924 428 PIRSF PIRSF001362 3 428 1.1E-233 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS02490 98927260a3483192bdead19386b22924 428 SUPERFAMILY SSF51621 8 427 2.96E-158 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS02490 98927260a3483192bdead19386b22924 428 Pfam PF00463 Isocitrate lyase family 12 251 8.7E-53 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS02490 98927260a3483192bdead19386b22924 428 Pfam PF00463 Isocitrate lyase family 252 426 1.6E-47 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS02490 98927260a3483192bdead19386b22924 428 Gene3D G3DSA:3.20.20.60 5 410 1.4E-145 T 28-03-2018 CP478_RS02490 98927260a3483192bdead19386b22924 428 ProSitePatterns PS00161 Isocitrate lyase signature. 189 194 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CP478_RS02490 98927260a3483192bdead19386b22924 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 11 251 1.5E-108 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS02490 98927260a3483192bdead19386b22924 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 252 427 3.6E-86 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 Pfam PF00672 HAMP domain 186 234 2.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SMART SM00387 351 466 1.1E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 2.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 2.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 2.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 2.5E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 463 2.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SUPERFAMILY SSF55874 301 464 9.56E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SMART SM00304 186 238 8.2E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SUPERFAMILY SSF47384 222 312 5.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 311 2.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SMART SM00388 239 311 4.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 Gene3D G3DSA:1.10.287.130 229 307 3.2E-12 T 28-03-2018 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 SUPERFAMILY SSF158472 189 235 1.44E-6 T 28-03-2018 CP478_RS05365 34404965fe1d94e8092e4c70fbba03b6 504 Gene3D G3DSA:3.30.565.10 313 467 3.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 SMART SM00220 16 275 1.8E-52 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 Gene3D G3DSA:1.10.510.10 112 289 5.9E-42 T 28-03-2018 CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 SUPERFAMILY SSF52833 383 565 1.03E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 Gene3D G3DSA:3.30.200.20 6 111 1.9E-18 T 28-03-2018 CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 SUPERFAMILY SSF56112 13 326 1.01E-67 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 Pfam PF13462 Thioredoxin 389 565 5.3E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 Pfam PF00069 Protein kinase domain 16 229 1.3E-42 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS09510 48c3d6fe8d1ca4416a2001965a00eb60 566 Gene3D G3DSA:3.40.30.10 387 566 1.3E-22 T 28-03-2018 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Gene3D G3DSA:3.30.1360.10 4 84 3.7E-17 T 28-03-2018 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Gene3D G3DSA:3.30.1360.10 107 221 2.2E-28 T 28-03-2018 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 4.2E-115 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Gene3D G3DSA:1.10.150.20 239 322 9.9E-25 T 28-03-2018 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 SUPERFAMILY SSF55257 14 48 2.55E-26 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 SUPERFAMILY SSF55257 170 220 2.55E-26 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 SMART SM00662 18 225 6.6E-98 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 241 302 3.0E-26 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 SUPERFAMILY SSF56553 48 169 9.29E-43 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.3E-20 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 SUPERFAMILY SSF47789 247 318 4.84E-24 T 28-03-2018 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 321 2.0E-35 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.799 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS18920 f131fbd5b77c7a2c87922fdec811be32 347 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.4E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS11035 9f58777c1d3d942b252c8737ee33af1a 201 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 86 181 1.6E-21 T 28-03-2018 IPR009241 Toxin HigB-like CP478_RS07025 3e59d62d4749411798166540615b16fa 332 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 37 332 55.383 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CP478_RS07025 3e59d62d4749411798166540615b16fa 332 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 63 285 4.4E-50 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CP478_RS07025 3e59d62d4749411798166540615b16fa 332 SUPERFAMILY SSF52402 37 240 3.31E-64 T 28-03-2018 CP478_RS07025 3e59d62d4749411798166540615b16fa 332 Gene3D G3DSA:3.40.50.620 35 299 4.5E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS07025 3e59d62d4749411798166540615b16fa 332 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 42 332 3.0E-147 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CP478_RS07025 3e59d62d4749411798166540615b16fa 332 PIRSF PIRSF002936 34 332 1.3E-138 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CP478_RS14455 2620728e8f70afda45fbe6faac7b388c 110 SUPERFAMILY SSF103481 8 108 1.27E-8 T 28-03-2018 CP478_RS14455 2620728e8f70afda45fbe6faac7b388c 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 3 108 21.609 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CP478_RS14455 2620728e8f70afda45fbe6faac7b388c 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 109 1.1E-48 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CP478_RS15230 6b7534ea5fe6a570529f2b87ccafc57d 344 Pfam PF03060 Nitronate monooxygenase 8 340 1.0E-119 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS15230 6b7534ea5fe6a570529f2b87ccafc57d 344 SUPERFAMILY SSF51412 3 72 3.82E-49 T 28-03-2018 CP478_RS15230 6b7534ea5fe6a570529f2b87ccafc57d 344 SUPERFAMILY SSF51412 109 291 3.82E-49 T 28-03-2018 CP478_RS15230 6b7534ea5fe6a570529f2b87ccafc57d 344 Gene3D G3DSA:3.20.20.70 3 344 1.8E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 PRINTS PR01228 Eggshell protein signature 396 414 2.5E-5 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 PRINTS PR01228 Eggshell protein signature 247 258 2.5E-5 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 PRINTS PR01228 Eggshell protein signature 364 374 2.5E-5 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 PRINTS PR01228 Eggshell protein signature 334 349 2.5E-5 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 SUPERFAMILY SSF140459 8 83 2.04E-25 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 Gene3D G3DSA:1.10.287.1060 1 101 1.2E-4 T 28-03-2018 CP478_RS07965 91e56de646a4f22cbef441481e1cf0da 738 Pfam PF00934 PE family 1 93 2.5E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 52 174 2.3E-9 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 238 351 2.3E-15 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 Gene3D G3DSA:3.40.50.300 5 195 2.1E-5 T 28-03-2018 CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 SMART SM00833 235 351 4.6E-35 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 Gene3D G3DSA:3.30.1220.10 205 351 2.1E-15 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 SUPERFAMILY SSF90002 239 298 1.31E-6 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CP478_RS00585 a54b5715ebe2c0e1edfbe14c2ddf8629 398 SUPERFAMILY SSF90002 325 351 1.31E-6 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 Gene3D G3DSA:2.60.120.10 43 170 1.9E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 SUPERFAMILY SSF46785 177 243 4.94E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 SMART SM00419 187 235 5.6E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 Pfam PF13545 Crp-like helix-turn-helix domain 180 241 1.3E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 SMART SM00100 41 158 3.9E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 Gene3D G3DSA:1.10.10.10 171 244 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 SUPERFAMILY SSF51206 45 169 1.96E-24 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS09150 df8853b4bff048313204bcf6890f3962 244 Pfam PF00027 Cyclic nucleotide-binding domain 60 146 1.1E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 SUPERFAMILY SSF51735 33 261 1.68E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 2.6E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 42 59 2.6E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 127 2.6E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 2.6E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 Pfam PF00106 short chain dehydrogenase 41 233 2.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 116 127 6.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 211 6.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 6.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02930 dfb158a05fd32143d890ac91f5a5efef 294 Gene3D G3DSA:3.40.50.720 27 293 1.4E-47 T 28-03-2018 CP478_RS09935 4bbe2871912cde9d5fc9afe8d3f91354 292 Gene3D G3DSA:1.20.1600.10 9 235 2.1E-4 T 28-03-2018 CP478_RS09935 4bbe2871912cde9d5fc9afe8d3f91354 292 Pfam PF05949 Bacterial protein of unknown function (DUF881) 151 289 3.6E-36 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 SMART SM00044 326 516 1.2E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 Gene3D G3DSA:3.30.70.1230 339 532 1.4E-40 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 SUPERFAMILY SSF158472 280 327 8.5E-6 T 28-03-2018 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 360 528 1.8E-20 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 Pfam PF00672 HAMP domain 281 326 8.9E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 SUPERFAMILY SSF55073 353 531 8.32E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS07235 e6193dbcfec1bb305823fa63eb4c64f5 535 SMART SM00304 278 330 3.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS05295 13dffbdd99937b8e4e4856d73b1c0f6e 210 Pfam PF17197 Domain of unknown function (DUF5134) 36 206 3.0E-37 T 28-03-2018 IPR033458 Protein of unknown function DUF5134 CP478_RS05295 13dffbdd99937b8e4e4856d73b1c0f6e 210 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 192 1.0E-91 T 28-03-2018 CP478_RS11270 ddb93cdec999b6b040542ee3f0fa4459 407 SUPERFAMILY SSF53335 9 157 1.36E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11270 ddb93cdec999b6b040542ee3f0fa4459 407 SUPERFAMILY SSF53335 225 259 1.36E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11270 ddb93cdec999b6b040542ee3f0fa4459 407 Pfam PF13847 Methyltransferase domain 58 156 1.8E-14 T 28-03-2018 IPR025714 Methyltransferase domain CP478_RS11270 ddb93cdec999b6b040542ee3f0fa4459 407 Gene3D G3DSA:3.40.50.150 4 299 2.0E-20 T 28-03-2018 CP478_RS03195 49d6360fec872a39128c3a4532298dfb 411 Gene3D G3DSA:3.40.50.300 19 191 0.0015 T 28-03-2018 CP478_RS03195 49d6360fec872a39128c3a4532298dfb 411 Pfam PF13173 AAA domain 20 136 3.1E-20 T 28-03-2018 CP478_RS03195 49d6360fec872a39128c3a4532298dfb 411 Gene3D G3DSA:1.10.10.10 197 274 4.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03195 49d6360fec872a39128c3a4532298dfb 411 Pfam PF13635 Domain of unknown function (DUF4143) 202 358 1.9E-25 T 28-03-2018 IPR025420 Domain of unknown function DUF4143 CP478_RS03195 49d6360fec872a39128c3a4532298dfb 411 SUPERFAMILY SSF52540 19 142 1.8E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11590 38f068e5eec04774e9bfdf44b2ff0fc6 267 Pfam PF00459 Inositol monophosphatase family 45 244 4.6E-27 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS11590 38f068e5eec04774e9bfdf44b2ff0fc6 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 88 101 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CP478_RS11590 38f068e5eec04774e9bfdf44b2ff0fc6 267 Gene3D G3DSA:3.30.540.10 7 151 6.1E-24 T 28-03-2018 CP478_RS11590 38f068e5eec04774e9bfdf44b2ff0fc6 267 Gene3D G3DSA:3.40.190.80 152 267 2.4E-18 T 28-03-2018 CP478_RS11590 38f068e5eec04774e9bfdf44b2ff0fc6 267 SUPERFAMILY SSF56655 14 264 3.4E-47 T 28-03-2018 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 Gene3D G3DSA:3.40.50.720 8 92 4.2E-9 T 28-03-2018 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 198 220 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 374 393 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 9 28 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 175 196 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 426 443 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 395 417 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 PRINTS PR00757 Flavin-containing amine oxidase signature 294 313 7.8E-33 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 Gene3D G3DSA:3.90.660.10 201 391 3.7E-34 T 28-03-2018 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 Pfam PF01593 Flavin containing amine oxidoreductase 17 444 1.5E-72 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 SUPERFAMILY SSF51905 408 447 4.92E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 SUPERFAMILY SSF51905 7 309 4.92E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 SUPERFAMILY SSF54373 291 394 6.54E-26 T 28-03-2018 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 Gene3D G3DSA:3.50.50.60 392 448 3.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17350 32a244db306dee2ac3a37ee0ee06dfa9 448 Gene3D G3DSA:1.10.405.10 109 200 1.9E-23 T 28-03-2018 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 9.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 9.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 9.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 SUPERFAMILY SSF53474 4 257 6.22E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 Gene3D G3DSA:3.40.50.1820 2 260 4.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00412 Epoxide hydrolase signature 83 96 1.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00412 Epoxide hydrolase signature 235 257 1.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 PRINTS PR00412 Epoxide hydrolase signature 40 55 1.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS17560 2a7094d3ea6e15a044701a8c70a882f8 261 Pfam PF12697 Alpha/beta hydrolase family 18 252 4.3E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 SUPERFAMILY SSF52540 4 582 8.92E-125 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Pfam PF00570 HRDC domain 630 696 1.6E-21 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Gene3D G3DSA:1.10.150.80 610 698 2.2E-21 T 28-03-2018 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 SMART SM00341 626 700 4.1E-19 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Pfam PF13361 UvrD-like helicase C-terminal domain 293 429 9.9E-17 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Pfam PF13361 UvrD-like helicase C-terminal domain 492 561 2.5E-19 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Gene3D G3DSA:3.40.50.300 290 586 3.0E-53 T 28-03-2018 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Gene3D G3DSA:3.40.50.300 5 289 9.9E-49 T 28-03-2018 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 286 1.9E-45 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CP478_RS17525 f893892953d8a6938ed2c0fee493ed37 700 SUPERFAMILY SSF47819 620 698 1.11E-20 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CP478_RS03430 6ec950f1b3a878bc2fbc246d9b7486b1 158 PIRSF PIRSF018072 2 150 1.2E-53 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS03430 6ec950f1b3a878bc2fbc246d9b7486b1 158 Hamap MF_00799 UPF0336 protein . 1 148 34.927 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS03430 6ec950f1b3a878bc2fbc246d9b7486b1 158 Gene3D G3DSA:3.10.129.10 4 156 4.5E-25 T 28-03-2018 CP478_RS03430 6ec950f1b3a878bc2fbc246d9b7486b1 158 Pfam PF13452 N-terminal half of MaoC dehydratase 8 137 4.3E-27 T 28-03-2018 CP478_RS03430 6ec950f1b3a878bc2fbc246d9b7486b1 158 SUPERFAMILY SSF54637 7 156 2.19E-34 T 28-03-2018 IPR029069 HotDog domain CP478_RS15055 e8ea5bc84f843b6470bc2f1a1f6607d5 174 SUPERFAMILY SSF55729 12 134 1.08E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS15055 e8ea5bc84f843b6470bc2f1a1f6607d5 174 Pfam PF00583 Acetyltransferase (GNAT) family 47 127 4.9E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS15055 e8ea5bc84f843b6470bc2f1a1f6607d5 174 Gene3D G3DSA:3.40.630.30 4 148 1.1E-19 T 28-03-2018 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 487 1.9E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Gene3D G3DSA:3.30.300.30 399 502 1.1E-29 T 28-03-2018 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Gene3D G3DSA:3.40.50.980 1 167 3.6E-44 T 28-03-2018 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Gene3D G3DSA:3.40.50.980 168 316 1.8E-39 T 28-03-2018 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Pfam PF00501 AMP-binding enzyme 9 404 2.4E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 Gene3D G3DSA:2.30.38.10 317 397 8.8E-20 T 28-03-2018 CP478_RS16895 2f1789a42f567927fa572bb26f7df2ab 503 SUPERFAMILY SSF56801 5 499 1.7E-145 T 28-03-2018 CP478_RS20885 8d3ea42844dee698852ae3e1b786402d 511 SUPERFAMILY SSF52777 242 464 3.67E-18 T 28-03-2018 CP478_RS20885 8d3ea42844dee698852ae3e1b786402d 511 Gene3D G3DSA:3.30.559.10 25 214 9.5E-7 T 28-03-2018 CP478_RS20885 8d3ea42844dee698852ae3e1b786402d 511 Pfam PF00668 Condensation domain 71 384 1.3E-14 T 28-03-2018 IPR001242 Condensation domain CP478_RS20885 8d3ea42844dee698852ae3e1b786402d 511 SUPERFAMILY SSF52777 41 212 2.67E-15 T 28-03-2018 CP478_RS18130 4e17365e76fdc1589d933001722d8c9c 299 Pfam PF04185 Phosphoesterase family 70 282 7.7E-43 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CP478_RS18130 4e17365e76fdc1589d933001722d8c9c 299 Gene3D G3DSA:3.40.720.10 52 286 2.0E-13 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS18130 4e17365e76fdc1589d933001722d8c9c 299 SUPERFAMILY SSF53649 67 284 2.8E-9 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS12485 715e66ed047d991278fed6f794667554 323 Pfam PF00248 Aldo/keto reductase family 14 297 5.3E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS12485 715e66ed047d991278fed6f794667554 323 SUPERFAMILY SSF51430 11 303 3.54E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS12485 715e66ed047d991278fed6f794667554 323 Gene3D G3DSA:3.20.20.100 1 319 3.2E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CP478_RS18525 9b45e6e9da24a5f24ca357bb833ecc77 350 Pfam PF00348 Polyprenyl synthetase 67 304 1.8E-58 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CP478_RS18525 9b45e6e9da24a5f24ca357bb833ecc77 350 SUPERFAMILY SSF48576 34 332 2.3E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS18525 9b45e6e9da24a5f24ca357bb833ecc77 350 Gene3D G3DSA:1.10.600.10 17 349 6.1E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS18525 9b45e6e9da24a5f24ca357bb833ecc77 350 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 106 120 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS10820 643c9436600d504b7e55c2ba80fba7c9 142 SMART SM00637 40 140 1.8E-40 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CP478_RS10820 643c9436600d504b7e55c2ba80fba7c9 142 Pfam PF00553 Cellulose binding domain 41 139 2.2E-34 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CP478_RS10820 643c9436600d504b7e55c2ba80fba7c9 142 SUPERFAMILY SSF49384 36 140 6.21E-32 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CP478_RS10820 643c9436600d504b7e55c2ba80fba7c9 142 Gene3D G3DSA:2.60.40.290 31 140 2.5E-31 T 28-03-2018 CP478_RS11495 6dc05dc3deb4b2716e36db311a1b06ef 554 Pfam PF03136 Pup-ligase protein 52 507 8.7E-179 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CP478_RS11495 6dc05dc3deb4b2716e36db311a1b06ef 554 PIRSF PIRSF018077 57 549 4.4E-219 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CP478_RS11495 6dc05dc3deb4b2716e36db311a1b06ef 554 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 51 538 5.7E-243 T 28-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.5E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 SUPERFAMILY SSF53474 10 138 3.48E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 SUPERFAMILY SSF53474 206 277 3.48E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 Pfam PF12146 Serine aminopeptidase, S33 28 263 2.5E-79 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CP478_RS01000 255264569e901d2dd828aa5a555d8ce9 279 Gene3D G3DSA:3.40.50.1820 2 279 1.4E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20620 dbac9f3439d4c5f2c1b4cd7be200b51d 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 273 3.7E-40 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS20620 dbac9f3439d4c5f2c1b4cd7be200b51d 274 Gene3D G3DSA:3.90.226.10 1 223 7.7E-53 T 28-03-2018 CP478_RS20620 dbac9f3439d4c5f2c1b4cd7be200b51d 274 SUPERFAMILY SSF52096 4 273 3.13E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS20620 dbac9f3439d4c5f2c1b4cd7be200b51d 274 Gene3D G3DSA:1.10.12.10 224 273 1.5E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS00710 59ade1bcbedfbe29af0aa16a4ee26002 151 Pfam PF01575 MaoC like domain 11 131 1.2E-33 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS00710 59ade1bcbedfbe29af0aa16a4ee26002 151 Gene3D G3DSA:3.10.129.10 1 151 7.7E-39 T 28-03-2018 CP478_RS00710 59ade1bcbedfbe29af0aa16a4ee26002 151 SUPERFAMILY SSF54637 3 148 3.88E-41 T 28-03-2018 IPR029069 HotDog domain CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 SUPERFAMILY SSF47648 27 93 5.76E-17 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 Pfam PF00591 Glycosyl transferase family, a/b domain 101 356 2.6E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 Gene3D G3DSA:1.20.970.10 25 91 1.6E-20 T 28-03-2018 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 SUPERFAMILY SSF52418 100 367 2.88E-78 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 32 365 2.8E-121 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 Gene3D G3DSA:3.40.1030.10 98 370 2.7E-96 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 Pfam PF02885 Glycosyl transferase family, helical bundle domain 29 90 1.2E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CP478_RS11920 7a134455d8199628217f2ed930ec641b 370 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 29 366 34.421 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CP478_RS09740 1b988f6cb743d2eb8d87dd5e340dd5bf 393 Gene3D G3DSA:1.10.287.1060 22 105 2.9E-7 T 28-03-2018 CP478_RS09740 1b988f6cb743d2eb8d87dd5e340dd5bf 393 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 312 389 1.4E-19 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09740 1b988f6cb743d2eb8d87dd5e340dd5bf 393 Pfam PF00823 PPE family 5 161 5.5E-64 T 28-03-2018 IPR000030 PPE family CP478_RS09740 1b988f6cb743d2eb8d87dd5e340dd5bf 393 SUPERFAMILY SSF140459 2 173 2.25E-64 T 28-03-2018 CP478_RS05220 86e2e18ed4a7fd386e7983e8ed40f615 215 SUPERFAMILY SSF53328 14 212 4.71E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS05220 86e2e18ed4a7fd386e7983e8ed40f615 215 Pfam PF00551 Formyl transferase 14 191 4.0E-41 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS05220 86e2e18ed4a7fd386e7983e8ed40f615 215 Gene3D G3DSA:3.40.50.170 1 215 8.8E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS05220 86e2e18ed4a7fd386e7983e8ed40f615 215 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 14 197 27.21 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CP478_RS05220 86e2e18ed4a7fd386e7983e8ed40f615 215 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 200 5.1E-71 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 426 43.187 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 SUPERFAMILY SSF51338 368 428 1.8E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 SUPERFAMILY SSF51338 6 51 1.8E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 Gene3D G3DSA:2.30.40.10 2 66 3.5E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 Pfam PF01979 Amidohydrolase family 48 421 2.2E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 SUPERFAMILY SSF51556 52 367 1.08E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 13 426 1.3E-163 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 Gene3D G3DSA:3.20.20.140 67 378 1.5E-94 T 28-03-2018 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 Gene3D G3DSA:2.30.40.10 379 425 3.5E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS07570 375be0c1efa8144190e40c0522f7ca4e 430 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CP478_RS10925 4d2b98cca625c76335b1c902a67ac9e7 498 SUPERFAMILY SSF56112 27 283 1.04E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS10925 4d2b98cca625c76335b1c902a67ac9e7 498 Gene3D G3DSA:3.90.1200.10 57 326 5.4E-6 T 28-03-2018 CP478_RS10925 4d2b98cca625c76335b1c902a67ac9e7 498 SUPERFAMILY SSF52540 326 452 1.02E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS10925 4d2b98cca625c76335b1c902a67ac9e7 498 Gene3D G3DSA:3.40.50.300 327 497 1.3E-18 T 28-03-2018 CP478_RS10925 4d2b98cca625c76335b1c902a67ac9e7 498 Pfam PF13671 AAA domain 325 460 4.5E-15 T 28-03-2018 CP478_RS13195 2272993114ca775b89cd382be0aa89b0 280 SUPERFAMILY SSF82549 3 272 2.62E-65 T 28-03-2018 CP478_RS13195 2272993114ca775b89cd382be0aa89b0 280 Gene3D G3DSA:3.30.1180.10 147 273 1.7E-36 T 28-03-2018 CP478_RS13195 2272993114ca775b89cd382be0aa89b0 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 272 5.2E-69 T 28-03-2018 IPR003797 DegV CP478_RS13195 2272993114ca775b89cd382be0aa89b0 280 Gene3D G3DSA:3.40.50.10440 2 145 1.3E-37 T 28-03-2018 CP478_RS13195 2272993114ca775b89cd382be0aa89b0 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 272 9.3E-72 T 28-03-2018 IPR003797 DegV CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 7.6E-62 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 SUPERFAMILY SSF52161 5 144 7.72E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 Pfam PF00572 Ribosomal protein L13 15 137 1.7E-53 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 PIRSF PIRSF002181 3 147 2.1E-47 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 27.584 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CP478_RS18845 b2c0842adb5fc54c175dacc4773d778e 147 Gene3D G3DSA:3.90.1180.10 1 147 1.1E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 SUPERFAMILY SSF51735 9 168 7.39E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 PIRSF PIRSF000103 2 295 2.1E-75 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 Gene3D G3DSA:1.10.1040.10 168 290 5.4E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 165 7.2E-37 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 12 25 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 Gene3D G3DSA:3.40.50.720 1 167 2.2E-24 T 28-03-2018 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 280 3.0E-9 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CP478_RS04190 7cfc9b4c6389c2791a28a070fe6ac0c1 295 SUPERFAMILY SSF48179 168 288 3.29E-16 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS08110 d369233dd3b2ef6ab5f93b8b2433c5a3 317 Pfam PF01882 Protein of unknown function DUF58 56 137 4.9E-18 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CP478_RS08110 d369233dd3b2ef6ab5f93b8b2433c5a3 317 SUPERFAMILY SSF53300 95 229 8.89E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS08110 d369233dd3b2ef6ab5f93b8b2433c5a3 317 Gene3D G3DSA:3.40.50.410 68 274 1.4E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 95 215 4.6E-44 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 Gene3D G3DSA:3.50.50.60 20 206 1.4E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 SUPERFAMILY SSF143243 78 232 6.54E-46 T 28-03-2018 CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 67 224 28.543 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 95 216 7.9E-40 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17235 b3df4738fad598e408a0a30e1dabd74f 236 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 144 197 2.0E-25 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS03620 39b3b42620d2bd889bf8b765bb164440 59 Gene3D G3DSA:3.20.20.150 4 58 4.9E-4 T 28-03-2018 CP478_RS03620 39b3b42620d2bd889bf8b765bb164440 59 SUPERFAMILY SSF51658 2 58 1.45E-7 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SMART SM00382 497 634 1.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SMART SM00382 246 368 0.025 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Gene3D G3DSA:2.40.40.20 7 93 8.5E-17 T 28-03-2018 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SUPERFAMILY SSF52540 209 425 1.16E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SUPERFAMILY SSF52540 460 706 4.08E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 250 369 5.2E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 501 631 6.1E-39 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SMART SM01073 11 95 4.3E-18 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Gene3D G3DSA:1.10.8.60 378 456 8.9E-15 T 28-03-2018 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Gene3D G3DSA:1.10.8.60 640 724 1.6E-19 T 28-03-2018 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Gene3D G3DSA:3.40.50.300 457 639 5.9E-53 T 28-03-2018 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Gene3D G3DSA:3.40.50.300 205 377 2.7E-20 T 28-03-2018 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 22 94 7.9E-14 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 ProSitePatterns PS00674 AAA-protein family signature. 602 620 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CP478_RS02315 f6440b8e7b4d6d3fb18624248c502b8d 728 SUPERFAMILY SSF50692 22 93 1.21E-10 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS08515 3e4bab32f9c6e64876224df720a50dad 126 Gene3D G3DSA:1.20.1300.10 2 124 5.2E-40 T 28-03-2018 CP478_RS08515 3e4bab32f9c6e64876224df720a50dad 126 Pfam PF02300 Fumarate reductase subunit C 3 124 3.3E-40 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 CP478_RS08515 3e4bab32f9c6e64876224df720a50dad 126 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 1 126 5.0E-52 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 CP478_RS08515 3e4bab32f9c6e64876224df720a50dad 126 SUPERFAMILY SSF81343 2 125 1.28E-45 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS08515 3e4bab32f9c6e64876224df720a50dad 126 PIRSF PIRSF000180 1 126 7.9E-53 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 CP478_RS03480 7a92bcd84342a52c3603bf335fe1d77d 287 PIRSF PIRSF003085 2 287 1.2E-116 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS03480 7a92bcd84342a52c3603bf335fe1d77d 287 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 283 1.5E-124 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03480 7a92bcd84342a52c3603bf335fe1d77d 287 Gene3D G3DSA:3.40.50.150 1 287 1.5E-57 T 28-03-2018 CP478_RS03480 7a92bcd84342a52c3603bf335fe1d77d 287 SUPERFAMILY SSF53335 13 287 4.49E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 Gene3D G3DSA:1.10.10.60 1 59 4.2E-18 T 28-03-2018 CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.5E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 Gene3D G3DSA:1.10.357.10 60 206 1.7E-13 T 28-03-2018 CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 SUPERFAMILY SSF46689 3 84 2.14E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS18055 5744feca3cd3d41808a6ce689bd3e252 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS13860 2ccccd5fd07fa0efc2c47fe523d1c25d 463 Pfam PF11774 Lsr2 416 460 6.0E-6 T 28-03-2018 IPR024412 Lsr2 CP478_RS13860 2ccccd5fd07fa0efc2c47fe523d1c25d 463 Pfam PF02732 ERCC4 domain 283 398 1.5E-8 T 28-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CP478_RS13860 2ccccd5fd07fa0efc2c47fe523d1c25d 463 SMART SM00891 274 354 1.4E-10 T 28-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CP478_RS13860 2ccccd5fd07fa0efc2c47fe523d1c25d 463 Gene3D G3DSA:3.40.50.10130 270 404 1.2E-13 T 28-03-2018 CP478_RS13860 2ccccd5fd07fa0efc2c47fe523d1c25d 463 SUPERFAMILY SSF52980 274 408 5.09E-16 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS08450 02e4caed61229a62590d6ab39a439cab 136 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 61 81 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CP478_RS08450 02e4caed61229a62590d6ab39a439cab 136 PIRSF PIRSF002030 1 134 3.5E-51 T 28-03-2018 IPR016339 Truncated hemoglobin, group 1 CP478_RS08450 02e4caed61229a62590d6ab39a439cab 136 Gene3D G3DSA:1.10.490.10 1 136 6.2E-36 T 28-03-2018 CP478_RS08450 02e4caed61229a62590d6ab39a439cab 136 SUPERFAMILY SSF46458 3 126 1.21E-37 T 28-03-2018 IPR009050 Globin-like CP478_RS08450 02e4caed61229a62590d6ab39a439cab 136 Pfam PF01152 Bacterial-like globin 14 127 7.9E-35 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CP478_RS03760 538c8c5d38f485c9290bfb694f5e421e 251 TIGRFAM TIGR03964 mycofact_creat: mycofactocin system creatininase family protein 15 250 2.8E-108 T 28-03-2018 IPR023871 Mycofactocin system creatininase family protein CP478_RS03760 538c8c5d38f485c9290bfb694f5e421e 251 Pfam PF02633 Creatinine amidohydrolase 24 237 3.3E-57 T 28-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CP478_RS03760 538c8c5d38f485c9290bfb694f5e421e 251 Gene3D G3DSA:3.40.50.10310 14 246 2.4E-62 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CP478_RS03760 538c8c5d38f485c9290bfb694f5e421e 251 SUPERFAMILY SSF102215 25 243 1.07E-58 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CP478_RS11615 ef84ba50e62df9bd4127318d040070eb 276 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 261 2.2E-104 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CP478_RS11615 ef84ba50e62df9bd4127318d040070eb 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 268 17.315 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CP478_RS11615 ef84ba50e62df9bd4127318d040070eb 276 Pfam PF02673 Bacitracin resistance protein BacA 7 262 1.9E-76 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CP478_RS10625 44720dd11e1348207acadac4ccc6713f 103 SUPERFAMILY SSF88723 3 74 4.21E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10625 44720dd11e1348207acadac4ccc6713f 103 Gene3D G3DSA:3.40.50.1010 2 86 7.6E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS04845 c65ab9a7e561c45283b5eb1137c6cd5f 490 Gene3D G3DSA:3.60.10.10 226 482 7.1E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS04845 c65ab9a7e561c45283b5eb1137c6cd5f 490 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 228 473 4.1E-12 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS04845 c65ab9a7e561c45283b5eb1137c6cd5f 490 SUPERFAMILY SSF56219 224 478 2.62E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CP478_RS04845 c65ab9a7e561c45283b5eb1137c6cd5f 490 Gene3D G3DSA:2.60.120.640 110 225 8.3E-11 T 28-03-2018 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 SUPERFAMILY SSF56645 76 289 1.2E-58 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Gene3D G3DSA:1.20.140.10 271 449 6.6E-44 T 28-03-2018 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 SUPERFAMILY SSF47203 277 436 3.22E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 58 163 6.3E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 264 1.5E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 435 8.7E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Gene3D G3DSA:2.40.110.10 166 270 9.8E-32 T 28-03-2018 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Gene3D G3DSA:1.10.540.10 17 165 1.7E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS04765 a5e6dd857456eff30a6c306536d8c499 650 Gene3D G3DSA:1.20.140.10 490 584 0.11 T 28-03-2018 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 Gene3D G3DSA:3.40.1410.10 90 254 1.6E-38 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 SUPERFAMILY SSF46785 19 88 3.67E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 SMART SM00345 26 85 1.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 3.1E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 3.1E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 Gene3D G3DSA:1.10.10.10 9 89 4.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 Pfam PF07702 UTRA domain 107 246 1.4E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 SUPERFAMILY SSF64288 73 253 2.98E-40 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 85 8.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS04305 c3fdfbe4fdc14cf6ada926bbb5b37079 269 SMART SM00866 106 246 5.2E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CP478_RS06415 2475899eb4665916a8ae3be798838e9d 346 SUPERFAMILY SSF140459 2 170 4.18E-47 T 28-03-2018 CP478_RS06415 2475899eb4665916a8ae3be798838e9d 346 Gene3D G3DSA:1.10.287.1060 15 102 1.8E-6 T 28-03-2018 CP478_RS06415 2475899eb4665916a8ae3be798838e9d 346 Pfam PF00823 PPE family 6 159 4.6E-45 T 28-03-2018 IPR000030 PPE family CP478_RS06415 2475899eb4665916a8ae3be798838e9d 346 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 270 337 2.5E-7 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS20565 26f4f926bb7fe02623e31276ad833edc 229 Gene3D G3DSA:3.20.20.80 3 159 2.5E-12 T 28-03-2018 CP478_RS20565 26f4f926bb7fe02623e31276ad833edc 229 SUPERFAMILY SSF51445 15 149 4.74E-11 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 SUPERFAMILY SSF48264 21 407 9.82E-87 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 161 176 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 305 332 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 288 299 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 363 374 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 333 348 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 98 109 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 354 363 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 144 160 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00359 B-class P450 signature 204 226 5.6E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 Pfam PF00067 Cytochrome P450 220 384 3.1E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 356 365 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 Gene3D G3DSA:1.10.630.10 2 412 8.7E-66 T 28-03-2018 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00385 P450 superfamily signature 253 270 3.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00385 P450 superfamily signature 288 299 3.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00385 P450 superfamily signature 354 363 3.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS04230 949a8532555e7bb1b64e281a43053354 414 PRINTS PR00385 P450 superfamily signature 363 374 3.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS08880 5d6154b5e7f4a07fe41bb5cac7dadb3b 195 Pfam PF03729 Short repeat of unknown function (DUF308) 86 155 1.4E-6 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CP478_RS08880 5d6154b5e7f4a07fe41bb5cac7dadb3b 195 Pfam PF03729 Short repeat of unknown function (DUF308) 143 191 7.4E-8 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CP478_RS08880 5d6154b5e7f4a07fe41bb5cac7dadb3b 195 Pfam PF03729 Short repeat of unknown function (DUF308) 30 99 2.2E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 SUPERFAMILY SSF55620 16 199 1.7E-76 T 28-03-2018 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 Pfam PF01227 GTP cyclohydrolase I 22 199 2.9E-76 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 17 200 41.603 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 23 199 3.6E-72 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 Gene3D G3DSA:3.30.1130.10 68 202 2.7E-58 T 28-03-2018 CP478_RS19705 c6eb39efe5e2f52e4299a47dfb0fd7f9 202 Gene3D G3DSA:1.10.286.10 19 67 2.4E-21 T 28-03-2018 CP478_RS05200 f2f438a127ae80e9f49ec4675c8bdeec 282 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 257 2.9E-78 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CP478_RS05200 f2f438a127ae80e9f49ec4675c8bdeec 282 Pfam PF00296 Luciferase-like monooxygenase 18 228 5.7E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS05200 f2f438a127ae80e9f49ec4675c8bdeec 282 SUPERFAMILY SSF51679 18 275 6.71E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS05200 f2f438a127ae80e9f49ec4675c8bdeec 282 Gene3D G3DSA:3.20.20.30 16 236 4.3E-61 T 28-03-2018 CP478_RS05200 f2f438a127ae80e9f49ec4675c8bdeec 282 Gene3D G3DSA:3.20.20.30 237 279 0.025 T 28-03-2018 CP478_RS06215 32670816535390738af7b0a04f9fdc08 80 Gene3D G3DSA:3.40.47.10 8 77 9.2E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS06215 32670816535390738af7b0a04f9fdc08 80 SUPERFAMILY SSF53901 30 79 2.98E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS06215 32670816535390738af7b0a04f9fdc08 80 Pfam PF02803 Thiolase, C-terminal domain 30 78 2.8E-16 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS20535 c730192718372b5c7715e76067d6da14 100 Pfam PF06305 Lipopolysaccharide assembly protein A domain 43 94 3.3E-10 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CP478_RS12360 8e9300488176ef88132869d5615c4309 109 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 9 91 3.0E-30 T 28-03-2018 IPR020264 Uncharacterised protein family YidG CP478_RS12360 8e9300488176ef88132869d5615c4309 109 Pfam PF02656 Domain of unknown function (DUF202) 10 72 2.1E-12 T 28-03-2018 IPR003807 Domain of unknown function DUF202 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 SUPERFAMILY SSF55931 122 455 3.04E-97 T 28-03-2018 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 Pfam PF00120 Glutamine synthetase, catalytic domain 122 450 7.4E-101 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 SMART SM01230 121 374 7.0E-93 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 Gene3D G3DSA:3.30.590.10 118 457 1.3E-93 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 SUPERFAMILY SSF54368 12 119 5.62E-18 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS15635 b2761da1b9efd9250331b87320edb8f9 457 Gene3D G3DSA:3.10.20.70 17 117 1.0E-25 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS02520 4f36b98bb87a4e25247b266da8256d7f 234 SUPERFAMILY SSF46689 16 83 2.26E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS02520 4f36b98bb87a4e25247b266da8256d7f 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS02520 4f36b98bb87a4e25247b266da8256d7f 234 SUPERFAMILY SSF48498 97 207 4.6E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS02520 4f36b98bb87a4e25247b266da8256d7f 234 Gene3D G3DSA:1.10.10.60 14 76 2.1E-14 T 28-03-2018 CP478_RS02520 4f36b98bb87a4e25247b266da8256d7f 234 Gene3D G3DSA:1.10.357.10 77 208 4.2E-11 T 28-03-2018 CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 SUPERFAMILY SSF51735 1096 1224 1.84E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 SUPERFAMILY SSF51735 952 1054 1.84E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 SUPERFAMILY SSF53223 768 963 1.63E-21 T 28-03-2018 CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 Gene3D G3DSA:3.40.50.10860 795 933 0.0021 T 28-03-2018 CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 PIRSF PIRSF036761 1 1619 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 Gene3D G3DSA:3.40.50.720 945 1293 2.2E-53 T 28-03-2018 CP478_RS13535 054fdc7e16df769fe18ef9f4e280eca3 1624 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 96 1612 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CP478_RS07995 60dce8c007cba1c2f95e1079395653d2 313 SUPERFAMILY SSF52540 7 227 9.0E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07995 60dce8c007cba1c2f95e1079395653d2 313 Pfam PF00005 ABC transporter 28 166 1.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS07995 60dce8c007cba1c2f95e1079395653d2 313 SMART SM00382 36 214 7.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07995 60dce8c007cba1c2f95e1079395653d2 313 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS07995 60dce8c007cba1c2f95e1079395653d2 313 Gene3D G3DSA:3.40.50.300 8 240 1.3E-57 T 28-03-2018 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 266 302 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 Gene3D G3DSA:3.40.640.10 200 343 1.9E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 SUPERFAMILY SSF53383 17 452 1.82E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 Gene3D G3DSA:3.90.1150.10 12 182 4.7E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 17 456 95.152 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 18 453 2.8E-191 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 Pfam PF00202 Aminotransferase class-III 47 449 3.3E-88 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS02805 99fd222845200cc0b7b11ed1788cf669 462 Gene3D G3DSA:3.90.1150.10 344 459 3.2E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS14675 be148519de2a0ff7a8eae1b5f59b5e5f 231 Gene3D G3DSA:3.30.70.1100 128 228 1.3E-31 T 28-03-2018 CP478_RS14675 be148519de2a0ff7a8eae1b5f59b5e5f 231 Pfam PF06778 Chlorite dismutase 32 221 8.9E-73 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CP478_RS14675 be148519de2a0ff7a8eae1b5f59b5e5f 231 SUPERFAMILY SSF54909 4 230 1.69E-75 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS14675 be148519de2a0ff7a8eae1b5f59b5e5f 231 Gene3D G3DSA:3.30.70.1030 7 126 2.2E-38 T 28-03-2018 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 Pfam PF00067 Cytochrome P450 16 403 2.2E-62 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 SUPERFAMILY SSF48264 7 424 9.69E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00465 E-class P450 group IV signature 330 348 1.9E-18 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00465 E-class P450 group IV signature 225 251 1.9E-18 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00465 E-class P450 group IV signature 281 297 1.9E-18 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00465 E-class P450 group IV signature 356 372 1.9E-18 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00465 E-class P450 group IV signature 372 390 1.9E-18 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 Gene3D G3DSA:1.10.630.10 2 427 2.1E-90 T 28-03-2018 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00385 P450 superfamily signature 286 297 1.7E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00385 P450 superfamily signature 372 383 1.7E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00385 P450 superfamily signature 234 251 1.7E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09110 c2730a49f7d57013c06e5d1dd6073239 430 PRINTS PR00385 P450 superfamily signature 363 372 1.7E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03320 2de0eb2c6b5d297169bc2ad724100301 231 SUPERFAMILY SSF54197 76 220 1.6E-40 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS03320 2de0eb2c6b5d297169bc2ad724100301 231 Gene3D G3DSA:3.30.428.10 100 222 4.4E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS03320 2de0eb2c6b5d297169bc2ad724100301 231 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 76 220 8.5E-35 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 Pfam PF00934 PE family 1 93 6.4E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 SUPERFAMILY SSF140459 8 84 5.49E-24 T 28-03-2018 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 Gene3D G3DSA:1.10.287.1060 1 97 0.0027 T 28-03-2018 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 PRINTS PR01228 Eggshell protein signature 192 207 6.6E-6 T 28-03-2018 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 PRINTS PR01228 Eggshell protein signature 256 274 6.6E-6 T 28-03-2018 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 PRINTS PR01228 Eggshell protein signature 133 144 6.6E-6 T 28-03-2018 CP478_RS02855 ff3f3cf592cf65a9a8387608ddae373f 594 PRINTS PR01228 Eggshell protein signature 217 227 6.6E-6 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Gene3D G3DSA:1.20.1640.10 725 937 8.3E-24 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 SUPERFAMILY SSF82866 164 360 1.05E-26 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 TIGRFAM TIGR00833 actII: transport protein 31 940 0.0 T 28-03-2018 IPR004707 Membrane transport protein MmpL family GO:0016021 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Gene3D G3DSA:1.20.120.230 618 707 0.11 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Gene3D G3DSA:1.20.120.230 463 573 0.24 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Gene3D G3DSA:1.20.1640.10 154 375 3.4E-27 T 28-03-2018 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Pfam PF03176 MMPL family 63 393 4.5E-114 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 Pfam PF03176 MMPL family 618 949 2.2E-110 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS03655 fccd7173246f951d193fa9296dd7189a 964 SUPERFAMILY SSF82866 731 940 5.1E-30 T 28-03-2018 CP478_RS00600 dd0fd29212d384f27381889078b52535 496 Pfam PF00934 PE family 1 93 1.3E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00600 dd0fd29212d384f27381889078b52535 496 SUPERFAMILY SSF140459 8 84 3.92E-24 T 28-03-2018 CP478_RS00600 dd0fd29212d384f27381889078b52535 496 PRINTS PR01228 Eggshell protein signature 74 90 1.7E-5 T 28-03-2018 CP478_RS00600 dd0fd29212d384f27381889078b52535 496 PRINTS PR01228 Eggshell protein signature 244 262 1.7E-5 T 28-03-2018 CP478_RS00600 dd0fd29212d384f27381889078b52535 496 PRINTS PR01228 Eggshell protein signature 198 208 1.7E-5 T 28-03-2018 CP478_RS00600 dd0fd29212d384f27381889078b52535 496 PRINTS PR01228 Eggshell protein signature 173 188 1.7E-5 T 28-03-2018 CP478_RS00190 ffc250e1ec548ca135348346bc50624b 87 SUPERFAMILY SSF47336 4 75 2.22E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00190 ffc250e1ec548ca135348346bc50624b 87 Gene3D G3DSA:1.10.1200.10 1 87 2.5E-15 T 28-03-2018 CP478_RS00190 ffc250e1ec548ca135348346bc50624b 87 Pfam PF00550 Phosphopantetheine attachment site 5 66 2.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS00190 ffc250e1ec548ca135348346bc50624b 87 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 30 69 3.0E-4 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 PIRSF PIRSF006305 1 207 8.5E-37 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 198 6.6E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 SUPERFAMILY SSF52972 1 200 1.37E-45 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 Hamap MF_00528 Septum formation protein Maf [maf]. 3 206 28.089 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 Gene3D G3DSA:3.90.950.10 2 209 4.9E-54 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CP478_RS17990 66bef2a09a90cacac8e514e7c8afcd1b 222 Pfam PF02545 Maf-like protein 3 201 2.3E-40 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CP478_RS20970 c9c358971759be94bd8ca2b8bbb21549 258 SUPERFAMILY SSF50475 10 251 4.71E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS20970 c9c358971759be94bd8ca2b8bbb21549 258 Gene3D G3DSA:3.20.180.10 158 247 4.5E-17 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 CP478_RS10805 ab24f9fa8ed430412cda5b716a2940e7 76 SUPERFAMILY SSF69786 5 75 1.31E-18 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CP478_RS10805 ab24f9fa8ed430412cda5b716a2940e7 76 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 6 74 2.2E-19 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CP478_RS10805 ab24f9fa8ed430412cda5b716a2940e7 76 Hamap MF_00634 UPF0235 protein YggU [yggU]. 3 76 12.904 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CP478_RS10805 ab24f9fa8ed430412cda5b716a2940e7 76 Gene3D G3DSA:3.30.1200.10 3 76 9.8E-20 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CP478_RS10805 ab24f9fa8ed430412cda5b716a2940e7 76 SMART SM01152 1 76 3.5E-25 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 PIRSF PIRSF000498 1 201 2.5E-69 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 Pfam PF00677 Lumazine binding domain 100 187 1.4E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 Pfam PF00677 Lumazine binding domain 3 87 3.8E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 Gene3D G3DSA:2.40.30.20 1 93 1.0E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 SUPERFAMILY SSF63380 93 198 7.23E-31 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 SUPERFAMILY SSF63380 1 88 1.53E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 5.0E-59 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CP478_RS07730 81f4ab9faa149fb35742c043114c31ea 201 Gene3D G3DSA:2.40.30.20 94 194 1.2E-33 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CP478_RS04960 9b8c5680f60239afe2d825869502b460 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 142 1.5E-21 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS04960 9b8c5680f60239afe2d825869502b460 144 Gene3D G3DSA:3.30.530.20 2 144 7.4E-15 T 28-03-2018 IPR023393 START-like domain CP478_RS04960 9b8c5680f60239afe2d825869502b460 144 SUPERFAMILY SSF55961 1 140 8.89E-20 T 28-03-2018 CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 45 547 1.7E-87 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 49 310 6.9E-67 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 SMART SM00939 324 545 8.1E-61 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 SUPERFAMILY SSF53474 38 357 2.48E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 339 542 1.2E-26 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 Gene3D G3DSA:3.40.50.1820 32 352 4.6E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 SUPERFAMILY SSF49785 354 548 1.32E-51 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS15325 ba741765322cdc5ffed6f25501be81d2 549 Gene3D G3DSA:2.60.120.260 353 549 1.4E-49 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS09765 5bbab967281c3f1f1f2992fbbef3dbb4 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 1.4E-14 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS09765 5bbab967281c3f1f1f2992fbbef3dbb4 94 SUPERFAMILY SSF140453 2 93 1.83E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS09765 5bbab967281c3f1f1f2992fbbef3dbb4 94 PIRSF PIRSF037656 1 94 2.0E-58 T 28-03-2018 IPR009416 ESAT-6-like protein, Mycobacterium CP478_RS09765 5bbab967281c3f1f1f2992fbbef3dbb4 94 Gene3D G3DSA:1.10.287.1060 1 94 1.2E-12 T 28-03-2018 CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 99 109 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 SUPERFAMILY SSF52743 79 149 9.65E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 SUPERFAMILY SSF52743 237 491 9.65E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 Pfam PF00082 Subtilase family 236 482 3.3E-20 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 232 549 6.0E-85 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 PRINTS PR00723 Subtilisin serine protease family (S8) signature 432 448 3.7E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 PRINTS PR00723 Subtilisin serine protease family (S8) signature 129 142 3.7E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 PRINTS PR00723 Subtilisin serine protease family (S8) signature 94 113 3.7E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21240 53e48091d7a5144290ea04324ff161c4 550 Gene3D G3DSA:3.40.50.200 59 491 8.7E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS05475 0349a347f6f667631fbbcc308dff7a79 205 SUPERFAMILY SSF51197 41 200 2.61E-41 T 28-03-2018 CP478_RS05475 0349a347f6f667631fbbcc308dff7a79 205 Gene3D G3DSA:2.60.120.590 15 202 1.4E-32 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CP478_RS05475 0349a347f6f667631fbbcc308dff7a79 205 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 99 200 7.0E-15 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 180 1.1E-39 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 SUPERFAMILY SSF56176 4 181 4.2E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 Gene3D G3DSA:3.30.390.50 183 295 5.4E-27 T 28-03-2018 CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 SMART SM01092 186 287 8.9E-27 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 Gene3D G3DSA:3.30.465.10 70 180 2.3E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 186 286 3.3E-23 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 SUPERFAMILY SSF55447 186 290 1.44E-27 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CP478_RS02000 8bf777c18c1d793ef34a63930ceb2cf2 300 Gene3D G3DSA:3.30.43.10 2 55 2.2E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 Pfam PF04851 Type III restriction enzyme, res subunit 68 217 6.9E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 Gene3D G3DSA:3.40.50.300 304 474 6.3E-8 T 28-03-2018 CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 SMART SM00487 61 239 9.8E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 SUPERFAMILY SSF52540 179 249 1.4E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 SUPERFAMILY SSF52540 309 429 1.4E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 SUPERFAMILY SSF52540 59 221 5.9E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15930 8661d64d118b1c0d09ae609a97ca9fc4 626 Gene3D G3DSA:3.40.50.300 52 226 5.6E-22 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 340 1.9E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 Gene3D G3DSA:3.50.50.60 105 260 3.5E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 SUPERFAMILY SSF51905 14 348 2.96E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 3.7E-12 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 3.7E-12 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.7E-12 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 3.7E-12 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.7E-7 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 2.7E-7 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 2.7E-7 T 28-03-2018 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 Gene3D G3DSA:3.50.50.60 3 37 5.9E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 Gene3D G3DSA:3.50.50.60 38 104 1.0E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02085 3166e7b812e0087b5e7e2cef8ffac869 470 Gene3D G3DSA:3.50.50.60 284 364 9.7E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 Pfam PF13365 Trypsin-like peptidase domain 254 401 1.9E-36 T 28-03-2018 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 Gene3D G3DSA:2.30.42.10 438 528 3.1E-16 T 28-03-2018 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 SMART SM00228 440 514 9.0E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 Pfam PF13180 PDZ domain 440 522 2.6E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 331 355 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 394 411 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 263 275 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 372 389 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 472 484 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 PRINTS PR00834 HtrA/DegQ protease family signature 290 310 7.1E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 SUPERFAMILY SSF50494 229 436 7.39E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 Gene3D G3DSA:2.40.10.10 312 430 2.1E-41 T 28-03-2018 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 SUPERFAMILY SSF50156 422 523 9.73E-19 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS06700 cdb9e2497e6ff90a669ad636122c7aed 528 Gene3D G3DSA:2.40.10.10 213 311 4.8E-26 T 28-03-2018 CP478_RS03405 2433fa2f6956264ec9969f723ba4ae94 237 Pfam PF00753 Metallo-beta-lactamase superfamily 30 203 1.1E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS03405 2433fa2f6956264ec9969f723ba4ae94 237 SUPERFAMILY SSF56281 27 223 4.6E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS03405 2433fa2f6956264ec9969f723ba4ae94 237 Gene3D G3DSA:3.60.15.10 18 235 3.8E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS03405 2433fa2f6956264ec9969f723ba4ae94 237 SMART SM00849 28 203 6.4E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS13355 065ac60416da856526a174c264f3c020 491 SUPERFAMILY SSF118215 26 418 3.53E-99 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 208 227 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 91 116 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 161 183 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 24 44 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 344 363 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 PRINTS PR00173 Glutamate-aspartate symporter signature 309 335 1.3E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 Gene3D G3DSA:1.10.3860.10 19 425 2.9E-97 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS13355 065ac60416da856526a174c264f3c020 491 Pfam PF00375 Sodium:dicarboxylate symporter family 26 418 8.3E-96 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CP478_RS02810 2d0d90b6bfd98e7056c1835078f81b56 202 SMART SM00855 6 158 7.6E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS02810 2d0d90b6bfd98e7056c1835078f81b56 202 Gene3D G3DSA:3.40.50.1240 3 197 2.7E-32 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS02810 2d0d90b6bfd98e7056c1835078f81b56 202 SUPERFAMILY SSF53254 5 199 6.79E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS02810 2d0d90b6bfd98e7056c1835078f81b56 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 191 4.7E-38 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS15855 884a038188d94fdcad509d2054e95334 264 Gene3D G3DSA:3.30.420.10 13 244 7.1E-60 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS15855 884a038188d94fdcad509d2054e95334 264 SUPERFAMILY SSF53098 24 224 1.23E-60 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS15855 884a038188d94fdcad509d2054e95334 264 Pfam PF01351 Ribonuclease HII 36 215 1.1E-47 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CP478_RS15855 884a038188d94fdcad509d2054e95334 264 Hamap MF_00052_B Ribonuclease HII [rnhB]. 34 215 37.756 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CP478_RS14540 b7eb47c156401d4fdcbb4dc4ef0b9b5b 177 Gene3D G3DSA:3.20.16.10 16 174 3.1E-27 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CP478_RS14540 b7eb47c156401d4fdcbb4dc4ef0b9b5b 177 Pfam PF04586 Caudovirus prohead serine protease 18 161 1.3E-19 T 28-03-2018 IPR006433 Prohead protease CP478_RS14540 b7eb47c156401d4fdcbb4dc4ef0b9b5b 177 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 21 158 4.4E-47 T 28-03-2018 IPR006433 Prohead protease CP478_RS17340 d44490cfa61e308df381f7518a897ed3 378 Pfam PF01636 Phosphotransferase enzyme family 97 288 6.2E-21 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CP478_RS17340 d44490cfa61e308df381f7518a897ed3 378 SUPERFAMILY SSF56112 30 333 7.48E-34 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS17340 d44490cfa61e308df381f7518a897ed3 378 Gene3D G3DSA:3.90.1200.10 156 356 1.9E-16 T 28-03-2018 CP478_RS17340 d44490cfa61e308df381f7518a897ed3 378 Gene3D G3DSA:3.30.200.20 24 136 1.1E-17 T 28-03-2018 CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 Pfam PF00005 ABC transporter 19 166 3.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 SUPERFAMILY SSF52540 1 220 7.92E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 SMART SM00382 28 215 3.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 8.1E-88 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS16980 11a604fa32f17decade9fdae9da7b210 229 Gene3D G3DSA:3.40.50.300 1 224 3.1E-65 T 28-03-2018 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 SUPERFAMILY SSF51998 186 709 3.36E-187 T 28-03-2018 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 114 707 1.6E-159 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 110 182 4.6E-11 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 26 725 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 Gene3D G3DSA:3.20.70.20 90 712 5.3E-161 T 28-03-2018 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 437 460 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 476 498 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 588 615 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 393 404 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 262 281 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 PRINTS PR01183 Ribonucleotide reductase large chain signature 504 527 5.3E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 577 599 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 SUPERFAMILY SSF48168 25 185 4.58E-61 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 Pfam PF08343 Ribonucleotide reductase N-terminal 27 108 8.7E-32 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS16690 f91077b9f4a0e842d3f80265bba4d425 725 Pfam PF02867 Ribonucleotide reductase, barrel domain 187 704 2.0E-143 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS17405 0ec15066a07037658c557463e72fb434 429 Pfam PF13173 AAA domain 27 144 2.4E-18 T 28-03-2018 CP478_RS17405 0ec15066a07037658c557463e72fb434 429 Gene3D G3DSA:1.10.10.10 219 271 9.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17405 0ec15066a07037658c557463e72fb434 429 Gene3D G3DSA:3.40.50.300 4 139 1.3E-5 T 28-03-2018 CP478_RS17405 0ec15066a07037658c557463e72fb434 429 Pfam PF13635 Domain of unknown function (DUF4143) 210 371 1.9E-25 T 28-03-2018 IPR025420 Domain of unknown function DUF4143 CP478_RS17405 0ec15066a07037658c557463e72fb434 429 SUPERFAMILY SSF52540 16 217 1.06E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03985 5182f9f2f07c723511ae78223b53cd72 70 Gene3D G3DSA:3.40.50.970 7 70 7.8E-7 T 28-03-2018 CP478_RS03985 5182f9f2f07c723511ae78223b53cd72 70 SUPERFAMILY SSF52518 11 59 2.06E-7 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS03985 5182f9f2f07c723511ae78223b53cd72 70 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 58 4.7E-6 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 241 8.9E-4 T 28-03-2018 CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 SUPERFAMILY SSF51735 15 274 8.63E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 Pfam PF00106 short chain dehydrogenase 21 218 2.5E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 9.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 9.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 9.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 171 9.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 9.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 Gene3D G3DSA:3.40.50.720 15 317 8.8E-61 T 28-03-2018 CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 168 196 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 169 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 200 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19150 2bdc41e6bbda2167687395055fcd0e60 317 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19355 d2fa29e22ea61f81bdddf77a1f7557d4 129 Gene3D G3DSA:3.10.129.10 2 128 3.7E-17 T 28-03-2018 CP478_RS19355 d2fa29e22ea61f81bdddf77a1f7557d4 129 SUPERFAMILY SSF54637 4 120 8.14E-15 T 28-03-2018 IPR029069 HotDog domain CP478_RS13060 391ee186bc8bdd9a712a16751a207805 667 Pfam PF03169 OPT oligopeptide transporter protein 10 604 8.0E-112 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CP478_RS13060 391ee186bc8bdd9a712a16751a207805 667 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 10 606 4.3E-294 T 28-03-2018 IPR004814 Oligopeptide transporter OPT CP478_RS13060 391ee186bc8bdd9a712a16751a207805 667 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 9 604 8.9E-139 T 28-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 SUPERFAMILY SSF54913 4 106 6.67E-17 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 SUPERFAMILY SSF54913 124 222 6.67E-22 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 SUPERFAMILY SSF54913 247 343 2.89E-19 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Pfam PF02641 Uncharacterized ACR, COG1993 127 220 5.7E-18 T 28-03-2018 IPR003793 Domain of unknown function DUF190 CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Pfam PF02641 Uncharacterized ACR, COG1993 7 103 1.0E-16 T 28-03-2018 IPR003793 Domain of unknown function DUF190 CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Pfam PF02641 Uncharacterized ACR, COG1993 248 343 1.1E-20 T 28-03-2018 IPR003793 Domain of unknown function DUF190 CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Gene3D G3DSA:3.30.70.120 120 229 1.7E-19 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Gene3D G3DSA:3.30.70.120 1 115 3.2E-22 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS16805 2e62f751da74c65ba6b269c3e96bb9e4 369 Gene3D G3DSA:3.30.70.120 243 358 1.0E-23 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 Gene3D G3DSA:1.10.510.10 704 908 2.6E-4 T 28-03-2018 CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 SUPERFAMILY SSF56112 723 879 3.2E-5 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 Pfam PF03023 MviN-like protein 48 521 8.1E-135 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 Gene3D G3DSA:2.60.120.260 1008 1184 5.2E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 52 71 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 383 402 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 149 173 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 285 311 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 173 194 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 PRINTS PR01806 Virulence factor MviN signature 71 87 2.8E-16 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS21365 02b6fb526f0c2b31c587a0d8b2b1bee8 1184 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 23 545 2.9E-73 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CP478_RS16135 35e0e89407a84525c58f986a0c4df268 418 Gene3D G3DSA:3.40.50.720 3 136 7.7E-18 T 28-03-2018 CP478_RS16135 35e0e89407a84525c58f986a0c4df268 418 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 10 135 1.6E-9 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CP478_RS16135 35e0e89407a84525c58f986a0c4df268 418 SUPERFAMILY SSF51735 10 158 5.33E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08520 12b0907093ac1c94cfd421befe535fae 125 Pfam PF02313 Fumarate reductase subunit D 11 123 2.7E-32 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 CP478_RS08520 12b0907093ac1c94cfd421befe535fae 125 Gene3D G3DSA:1.20.1300.10 7 125 7.2E-16 T 28-03-2018 CP478_RS08520 12b0907093ac1c94cfd421befe535fae 125 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 5 125 21.386 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 CP478_RS08520 12b0907093ac1c94cfd421befe535fae 125 PIRSF PIRSF000179 5 125 8.5E-38 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 CP478_RS08520 12b0907093ac1c94cfd421befe535fae 125 SUPERFAMILY SSF81343 8 125 2.09E-37 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 Pfam PF02576 RimP N-terminal domain 22 89 6.7E-12 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 Gene3D G3DSA:3.30.300.70 6 86 5.0E-12 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 SUPERFAMILY SSF75420 7 89 1.27E-14 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 Pfam PF17384 RimP C-terminal SH3 domain 92 157 3.0E-10 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 9 157 18.725 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 SUPERFAMILY SSF74942 90 157 5.62E-5 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CP478_RS15540 3d657a63b2bf4a604ea23134e8e7b2fa 183 Gene3D G3DSA:2.30.30.180 94 155 1.7E-4 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CP478_RS16050 b38b800e40d5e6a34b8abe6c247859d9 276 Pfam PF01061 ABC-2 type transporter 34 237 6.3E-13 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CP478_RS16050 b38b800e40d5e6a34b8abe6c247859d9 276 TIGRFAM TIGR01248 drrC: daunorubicin resistance protein C 91 242 9.0E-68 T 28-03-2018 IPR005943 Daunorubicin resistance protein C CP478_RS16050 b38b800e40d5e6a34b8abe6c247859d9 276 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 46 274 1.6E-91 T 28-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 CP478_RS16050 b38b800e40d5e6a34b8abe6c247859d9 276 PIRSF PIRSF006648 4 275 1.0E-54 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CP478_RS14410 23029caa46e310a072b6c089a28dc555 432 Pfam PF01139 tRNA-splicing ligase RtcB 2 432 1.0E-147 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CP478_RS14410 23029caa46e310a072b6c089a28dc555 432 SUPERFAMILY SSF103365 2 432 6.54E-150 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CP478_RS14410 23029caa46e310a072b6c089a28dc555 432 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 2 31 - T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CP478_RS06390 51316db296cb525615a64a5e603e57cd 201 Gene3D G3DSA:1.10.3480.10 1 177 5.3E-26 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS06390 51316db296cb525615a64a5e603e57cd 201 SUPERFAMILY SSF89155 2 161 1.57E-24 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS06390 51316db296cb525615a64a5e603e57cd 201 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 6 156 3.2E-66 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CP478_RS06390 51316db296cb525615a64a5e603e57cd 201 Pfam PF02613 Nitrate reductase delta subunit 42 124 2.8E-8 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS20960 5a7f10937f6b0c919871fbc12d38173b 232 SMART SM00855 4 163 3.5E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS20960 5a7f10937f6b0c919871fbc12d38173b 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 202 3.2E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS20960 5a7f10937f6b0c919871fbc12d38173b 232 Gene3D G3DSA:3.40.50.1240 2 209 1.1E-33 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS20960 5a7f10937f6b0c919871fbc12d38173b 232 PIRSF PIRSF000709 2 172 3.3E-5 T 28-03-2018 CP478_RS20960 5a7f10937f6b0c919871fbc12d38173b 232 SUPERFAMILY SSF53254 2 203 2.94E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 32 139 6.9E-25 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 Gene3D G3DSA:3.40.710.10 312 601 1.8E-53 T 28-03-2018 CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 SUPERFAMILY SSF56601 306 596 6.95E-55 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 Pfam PF00905 Penicillin binding protein transpeptidase domain 326 581 2.4E-35 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 Gene3D G3DSA:3.90.1310.10 260 311 6.7E-4 T 28-03-2018 CP478_RS15660 c84fd9eed772223f83ed4a1665d20c20 603 Gene3D G3DSA:3.10.450.100 30 134 2.1E-8 T 28-03-2018 CP478_RS06715 c2f8a951512e3499fe8be4ae12e821a0 487 PIRSF PIRSF026631 1 487 4.2E-112 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CP478_RS06715 c2f8a951512e3499fe8be4ae12e821a0 487 Pfam PF03703 Bacterial PH domain 62 135 1.5E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CP478_RS06715 c2f8a951512e3499fe8be4ae12e821a0 487 Pfam PF03703 Bacterial PH domain 401 454 3.2E-4 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CP478_RS08295 1dc0534656c7e470b3691d8245b10ff2 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 16 247 4.1E-66 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS08295 1dc0534656c7e470b3691d8245b10ff2 322 SUPERFAMILY SSF51735 15 316 2.96E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08295 1dc0534656c7e470b3691d8245b10ff2 322 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 13 315 47.33 T 28-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 CP478_RS08295 1dc0534656c7e470b3691d8245b10ff2 322 Gene3D G3DSA:3.90.25.10 176 322 2.8E-43 T 28-03-2018 CP478_RS08295 1dc0534656c7e470b3691d8245b10ff2 322 Gene3D G3DSA:3.40.50.720 14 175 7.4E-15 T 28-03-2018 CP478_RS01745 39b770f26040ea29c2f3649d287db6fa 151 Pfam PF13649 Methyltransferase domain 1 78 7.5E-11 T 28-03-2018 CP478_RS01745 39b770f26040ea29c2f3649d287db6fa 151 Gene3D G3DSA:3.40.50.150 1 142 7.9E-18 T 28-03-2018 CP478_RS01745 39b770f26040ea29c2f3649d287db6fa 151 SUPERFAMILY SSF53335 1 134 4.76E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 Pfam PF12697 Alpha/beta hydrolase family 39 280 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 Gene3D G3DSA:3.40.50.1820 7 288 1.1E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 2.8E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 2.8E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 124 137 2.8E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 2.8E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19510 4e4fa259b71b65b2ba72710c3cb36f57 291 SUPERFAMILY SSF53474 17 288 1.22E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02005 b1d074bed41bdd90992d743ac2ffd7a0 380 Pfam PF13478 XdhC Rossmann domain 198 344 3.1E-41 T 28-03-2018 IPR027051 XdhC Rossmann domain CP478_RS02005 b1d074bed41bdd90992d743ac2ffd7a0 380 Pfam PF02625 XdhC and CoxI family 110 175 1.4E-17 T 28-03-2018 IPR003777 XdhC- CoxI CP478_RS02005 b1d074bed41bdd90992d743ac2ffd7a0 380 Pfam PF02625 XdhC and CoxI family 4 70 2.0E-21 T 28-03-2018 IPR003777 XdhC- CoxI CP478_RS17655 9a4e09769eb629d518fc5fd6a26e0de1 71 Pfam PF00364 Biotin-requiring enzyme 10 70 3.6E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CP478_RS17655 9a4e09769eb629d518fc5fd6a26e0de1 71 SUPERFAMILY SSF51230 5 70 1.57E-18 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS17655 9a4e09769eb629d518fc5fd6a26e0de1 71 Gene3D G3DSA:2.40.50.100 1 71 9.2E-16 T 28-03-2018 CP478_RS03555 abf8c8dc8e55e4277237d0b2a195a107 102 Gene3D G3DSA:2.30.30.110 1 102 6.5E-12 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS03555 abf8c8dc8e55e4277237d0b2a195a107 102 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 99 6.8E-11 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS03555 abf8c8dc8e55e4277237d0b2a195a107 102 SUPERFAMILY SSF50118 1 101 6.76E-18 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 Gene3D G3DSA:3.40.50.300 249 526 1.2E-46 T 28-03-2018 CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 Pfam PF00271 Helicase conserved C-terminal domain 257 365 9.2E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 SMART SM00487 29 248 4.3E-53 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 SUPERFAMILY SSF52540 85 383 1.8E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 Gene3D G3DSA:3.40.50.300 8 248 7.3E-54 T 28-03-2018 CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 177 185 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 SMART SM00490 284 365 8.1E-34 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS17605 e41e82891b696df5ce91beb86235a7e7 527 Pfam PF00270 DEAD/DEAH box helicase 35 216 1.1E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS12525 ab4ceb6e584b66cc6108a0ff0763e128 429 SUPERFAMILY SSF52777 223 427 1.45E-7 T 28-03-2018 CP478_RS12525 ab4ceb6e584b66cc6108a0ff0763e128 429 Pfam PF00668 Condensation domain 25 146 5.7E-5 T 28-03-2018 IPR001242 Condensation domain CP478_RS12525 ab4ceb6e584b66cc6108a0ff0763e128 429 Gene3D G3DSA:3.30.559.10 1 181 1.5E-18 T 28-03-2018 CP478_RS12525 ab4ceb6e584b66cc6108a0ff0763e128 429 SUPERFAMILY SSF52777 4 149 8.89E-17 T 28-03-2018 CP478_RS06125 e07519e525b13e0f9ca62eba5244e1ae 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 6.9E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CP478_RS06125 e07519e525b13e0f9ca62eba5244e1ae 107 SUPERFAMILY SSF54909 1 97 1.4E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS06125 e07519e525b13e0f9ca62eba5244e1ae 107 Gene3D G3DSA:3.30.70.100 1 101 4.9E-19 T 28-03-2018 CP478_RS08095 88c4f603785ff07793a73324c5633117 472 Pfam PF00877 NlpC/P60 family 355 469 1.4E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CP478_RS08095 88c4f603785ff07793a73324c5633117 472 Gene3D G3DSA:3.90.1720.10 336 472 2.8E-35 T 28-03-2018 CP478_RS08095 88c4f603785ff07793a73324c5633117 472 SUPERFAMILY SSF54001 341 469 4.22E-31 T 28-03-2018 CP478_RS08095 88c4f603785ff07793a73324c5633117 472 Gene3D G3DSA:1.20.1170.10 36 236 9.0E-5 T 28-03-2018 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 Gene3D G3DSA:3.30.70.20 72 129 2.4E-17 T 28-03-2018 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 SUPERFAMILY SSF54862 54 169 3.81E-26 T 28-03-2018 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 28 171 27.339 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 Gene3D G3DSA:3.30.70.20 130 206 8.0E-8 T 28-03-2018 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 126 137 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 37 164 1.7E-41 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 Pfam PF12838 4Fe-4S dicluster domain 80 140 5.1E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS17265 22b849a77245390f449b27e9a98cb7fe 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 105 115 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 463 479 1.2E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 137 150 1.2E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 100 119 1.2E-10 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 Gene3D G3DSA:3.40.50.200 63 528 2.3E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 SUPERFAMILY SSF52743 83 154 1.35E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 SUPERFAMILY SSF52743 266 523 1.35E-46 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 Pfam PF00082 Subtilase family 268 513 5.9E-20 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS09780 8daf39d39322eee248345478a7ce9686 585 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 266 582 4.1E-86 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 Pfam PF01336 OB-fold nucleic acid binding domain 64 139 2.4E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 Pfam PF00152 tRNA synthetases class II (D, K and N) 156 499 9.7E-69 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 16 503 36.454 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 12 503 1.1E-140 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 Gene3D G3DSA:3.30.930.10 151 500 1.3E-81 T 28-03-2018 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 1.8E-33 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.8E-33 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 1.8E-33 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 1.8E-33 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 1.8E-33 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 SUPERFAMILY SSF55681 156 501 1.14E-94 T 28-03-2018 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 Gene3D G3DSA:2.40.50.140 10 149 6.9E-36 T 28-03-2018 CP478_RS19655 5c4c625ca44dc4ac0f4715e9dfe5d842 505 SUPERFAMILY SSF50249 9 149 1.87E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 2.3E-22 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 Gene3D G3DSA:3.40.47.10 171 335 3.0E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 332 6.4E-135 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 SUPERFAMILY SSF53901 12 332 1.49E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 332 6.1E-31 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 Gene3D G3DSA:3.40.47.10 1 170 1.5E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS02860 bfb773dadaf46fbf4fadfc1bc83e0a1c 335 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 332 58.487 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 364 389 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 TIGRFAM TIGR00642 mmCoA_mut_beta: methylmalonyl-CoA mutase, small subunit 5 615 9.1E-293 T 28-03-2018 IPR004608 Methylmalonyl-CoA mutase, beta chain GO:0004494|GO:0019652|GO:0031419 KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 SUPERFAMILY SSF51703 33 518 1.02E-132 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 Gene3D G3DSA:3.40.50.280 484 615 1.2E-19 T 28-03-2018 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 SUPERFAMILY SSF52242 466 615 2.35E-32 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 Gene3D G3DSA:3.20.20.240 46 483 4.6E-125 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08180 eee06fde832dc0ff2ff36ca88fe0c7c5 615 Pfam PF01642 Methylmalonyl-CoA mutase 48 524 1.9E-124 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS06740 286532c37ce1b151e7a86eab90a420a7 411 Gene3D G3DSA:1.10.530.10 119 288 1.1E-26 T 28-03-2018 CP478_RS06740 286532c37ce1b151e7a86eab90a420a7 411 SUPERFAMILY SSF53955 78 277 3.37E-34 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS06740 286532c37ce1b151e7a86eab90a420a7 411 ProSitePatterns PS00032 'Homeobox' antennapedia-type protein signature. 341 346 - T 28-03-2018 IPR001827 Homeobox protein, antennapedia type, conserved site GO:0003677|GO:0003700|GO:0006355 CP478_RS06740 286532c37ce1b151e7a86eab90a420a7 411 Pfam PF13406 Transglycosylase SLT domain 194 248 2.3E-8 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CP478_RS10550 cf4a2b177b0c18ec983ebfdf3d735841 171 SMART SM00903 24 167 1.9E-45 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS10550 cf4a2b177b0c18ec983ebfdf3d735841 171 Pfam PF01613 Flavin reductase like domain 27 168 1.0E-28 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS10550 cf4a2b177b0c18ec983ebfdf3d735841 171 SUPERFAMILY SSF50475 16 168 1.96E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS10550 cf4a2b177b0c18ec983ebfdf3d735841 171 Gene3D G3DSA:2.30.110.10 12 171 4.7E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 SMART SM00382 46 246 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 22 266 4.9E-106 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 Pfam PF00005 ABC transporter 37 192 9.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 Gene3D G3DSA:3.40.50.300 18 275 2.2E-59 T 28-03-2018 CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 SUPERFAMILY SSF52540 24 256 4.44E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS05090 cbbd29424446260271ac1277f66edd16 276 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS17615 ca391dba689b371aa6bcfa0cbf3586c2 266 SUPERFAMILY SSF52540 4 260 8.22E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17615 ca391dba689b371aa6bcfa0cbf3586c2 266 Gene3D G3DSA:3.40.50.300 3 258 1.3E-55 T 28-03-2018 CP478_RS17615 ca391dba689b371aa6bcfa0cbf3586c2 266 Pfam PF13614 AAA domain 4 178 2.5E-54 T 28-03-2018 IPR025669 AAA domain CP478_RS17490 527657257d33eb7b31d2119299033a51 992 Hamap MF_01600 UPF0182 protein . 11 904 17.691 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CP478_RS17490 527657257d33eb7b31d2119299033a51 992 Pfam PF03699 Uncharacterised protein family (UPF0182) 20 820 5.4E-267 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CP478_RS03135 86a7089f0bd82230e163e107b4e70c1d 795 Gene3D G3DSA:1.10.510.10 334 437 5.5E-4 T 28-03-2018 CP478_RS03135 86a7089f0bd82230e163e107b4e70c1d 795 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 493 782 5.2E-32 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CP478_RS03135 86a7089f0bd82230e163e107b4e70c1d 795 SUPERFAMILY SSF56112 317 399 1.71E-5 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS03135 86a7089f0bd82230e163e107b4e70c1d 795 Gene3D G3DSA:1.20.1250.20 446 670 3.5E-4 T 28-03-2018 CP478_RS04835 546d9981b5b290f1217566ad761e1f08 152 Gene3D G3DSA:3.10.180.10 6 144 1.4E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04835 546d9981b5b290f1217566ad761e1f08 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 129 3.7E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS04835 546d9981b5b290f1217566ad761e1f08 152 SUPERFAMILY SSF54593 9 135 1.48E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS15170 c789f1b6f4c694bbfbcc000864e831a3 275 Pfam PF00934 PE family 1 94 5.8E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS15170 c789f1b6f4c694bbfbcc000864e831a3 275 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 193 273 6.8E-18 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS15170 c789f1b6f4c694bbfbcc000864e831a3 275 SUPERFAMILY SSF140459 8 85 2.28E-20 T 28-03-2018 CP478_RS20865 2ae29607828077e7789beb6258ac3ea7 468 SUPERFAMILY SSF52777 37 207 3.45E-14 T 28-03-2018 CP478_RS20865 2ae29607828077e7789beb6258ac3ea7 468 Gene3D G3DSA:3.30.559.10 17 219 8.4E-6 T 28-03-2018 CP478_RS20865 2ae29607828077e7789beb6258ac3ea7 468 SUPERFAMILY SSF52777 228 452 1.11E-15 T 28-03-2018 CP478_RS20865 2ae29607828077e7789beb6258ac3ea7 468 Pfam PF00668 Condensation domain 70 360 1.3E-14 T 28-03-2018 IPR001242 Condensation domain CP478_RS09950 ae8bbdac9b7eaca7e797d533c4bd23ff 247 Gene3D G3DSA:1.10.1660.10 3 242 1.0E-18 T 28-03-2018 CP478_RS09950 ae8bbdac9b7eaca7e797d533c4bd23ff 247 SMART SM00422 12 86 5.2E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS09950 ae8bbdac9b7eaca7e797d533c4bd23ff 247 Pfam PF00376 MerR family regulatory protein 24 54 2.5E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS09950 ae8bbdac9b7eaca7e797d533c4bd23ff 247 SUPERFAMILY SSF46955 27 92 5.04E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 PIRSF PIRSF002756 5 374 1.5E-76 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 53 372 5.2E-126 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 Gene3D G3DSA:3.40.190.10 183 372 1.2E-16 T 28-03-2018 CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 Pfam PF12849 PBP superfamily domain 47 342 1.7E-41 T 28-03-2018 IPR024370 PBP domain CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 SUPERFAMILY SSF53850 43 368 9.13E-74 T 28-03-2018 CP478_RS05095 5830fc7650413b50d15df2b5f868c3d3 374 Gene3D G3DSA:3.40.190.10 50 182 1.3E-26 T 28-03-2018 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 Pfam PF01238 Phosphomannose isomerase type I 5 367 4.6E-59 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 7 395 2.2E-66 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 Gene3D G3DSA:2.60.120.10 5 160 5.7E-40 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 4.2E-64 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 Gene3D G3DSA:1.10.441.10 161 271 6.9E-27 T 28-03-2018 CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 Gene3D G3DSA:2.60.120.10 304 408 4.3E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 SUPERFAMILY SSF51182 3 389 3.82E-96 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS17845 c275df40bd52e048b1de1b03b7dc5965 408 PIRSF PIRSF001480 1 408 1.1E-103 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 345 383 1.7E-10 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 302 341 3.6E-13 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 385 425 5.5E-13 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 Gene3D G3DSA:2.60.40.1180 347 380 1.4E-8 T 28-03-2018 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 Pfam PF01436 NHL repeat 291 317 2.3E-6 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 Gene3D G3DSA:2.130.10.10 381 453 3.9E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 SUPERFAMILY SSF50974 285 445 6.8E-38 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 SUPERFAMILY SSF140459 8 82 2.88E-20 T 28-03-2018 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 Gene3D G3DSA:2.130.10.10 217 346 5.4E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05355 ff17ab2b5be48dbf586ae1d23ac851fc 457 Pfam PF00934 PE family 1 92 8.0E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 185 294 1.4E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 103 4.3E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 SUPERFAMILY SSF47203 182 296 9.99E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 SUPERFAMILY SSF56645 3 136 1.27E-15 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 Gene3D G3DSA:1.10.540.10 1 116 1.5E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19475 91b60ded07462c22e34fc705eff56513 318 Gene3D G3DSA:1.20.140.10 180 298 8.7E-29 T 28-03-2018 CP478_RS01265 ebf2d0c649aa7451a607ebb2798b85a8 511 SUPERFAMILY SSF53720 57 510 6.94E-148 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS01265 ebf2d0c649aa7451a607ebb2798b85a8 511 Pfam PF00171 Aldehyde dehydrogenase family 57 508 8.6E-144 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS01265 ebf2d0c649aa7451a607ebb2798b85a8 511 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 312 323 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS01265 ebf2d0c649aa7451a607ebb2798b85a8 511 Gene3D G3DSA:3.40.309.10 301 494 1.1E-72 T 28-03-2018 CP478_RS01265 ebf2d0c649aa7451a607ebb2798b85a8 511 Gene3D G3DSA:3.40.605.10 39 300 5.4E-72 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 Gene3D G3DSA:3.40.50.7700 2 166 9.7E-71 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 SMART SM01001 8 157 2.2E-93 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 Pfam PF00731 AIR carboxylase 9 154 1.6E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 164 3.3E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 SUPERFAMILY SSF52255 8 167 1.83E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 PIRSF PIRSF001338 5 168 6.1E-67 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CP478_RS17955 2c58596519d5e91de9f7a2ae2ea182e1 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 161 32.788 T 28-03-2018 IPR033747 Class I PurE CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 PRINTS PR01755 Bacterial translocase SecF protein signature 253 271 3.9E-22 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 PRINTS PR01755 Bacterial translocase SecF protein signature 85 100 3.9E-22 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 PRINTS PR01755 Bacterial translocase SecF protein signature 205 219 3.9E-22 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 PRINTS PR01755 Bacterial translocase SecF protein signature 288 303 3.9E-22 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 58 356 23.756 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 SUPERFAMILY SSF82866 136 355 3.27E-28 T 28-03-2018 CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 Pfam PF07549 SecD/SecF GG Motif 81 99 4.4E-6 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 Pfam PF02355 Protein export membrane protein 167 354 7.2E-64 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 Gene3D G3DSA:1.20.1640.10 129 366 1.3E-23 T 28-03-2018 CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 86 345 1.7E-78 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CP478_RS14170 e6da115a3b5ab26e9ac02755031f90b7 442 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 172 342 8.0E-52 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CP478_RS12695 2fd24d7619863da435389a4ca5e268dc 382 SUPERFAMILY SSF140459 8 84 2.3E-23 T 28-03-2018 CP478_RS12695 2fd24d7619863da435389a4ca5e268dc 382 Pfam PF00934 PE family 1 92 2.9E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS12695 2fd24d7619863da435389a4ca5e268dc 382 Gene3D G3DSA:1.10.287.850 1 94 2.4E-4 T 28-03-2018 CP478_RS01550 2367d89911c54edf0c91c1ce82eb9418 97 Pfam PF06013 Proteins of 100 residues with WXG 10 87 1.1E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS01550 2367d89911c54edf0c91c1ce82eb9418 97 SUPERFAMILY SSF140453 4 93 9.94E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS01550 2367d89911c54edf0c91c1ce82eb9418 97 Gene3D G3DSA:1.10.287.1060 1 97 3.5E-11 T 28-03-2018 CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 SUPERFAMILY SSF54637 10 120 8.82E-24 T 28-03-2018 IPR029069 HotDog domain CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 SUPERFAMILY SSF54637 122 286 8.95E-40 T 28-03-2018 IPR029069 HotDog domain CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 Gene3D G3DSA:3.10.129.10 136 289 1.4E-42 T 28-03-2018 CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 Pfam PF02551 Acyl-CoA thioesterase 23 111 4.1E-9 T 28-03-2018 IPR025652 Acyl-CoA thioesterase II domain CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 Pfam PF02551 Acyl-CoA thioesterase 154 285 2.1E-47 T 28-03-2018 IPR025652 Acyl-CoA thioesterase II domain CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 Gene3D G3DSA:3.10.129.10 7 122 3.6E-26 T 28-03-2018 CP478_RS08850 1cb56f37248c936f37516f8178d65d40 300 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 17 287 4.9E-90 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 5 241 1.3E-130 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 Pfam PF12857 TOBE-like domain 270 325 9.9E-11 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 SUPERFAMILY SSF52540 5 241 8.25E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 Gene3D G3DSA:2.40.50.100 256 325 2.9E-13 T 28-03-2018 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 SMART SM00382 29 212 1.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 SUPERFAMILY SSF50331 245 324 5.95E-8 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 Gene3D G3DSA:3.40.50.300 1 255 3.4E-80 T 28-03-2018 CP478_RS13080 90c74d82d2ac3e478b7665b1d7385d74 351 Pfam PF00005 ABC transporter 20 162 4.1E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS05010 6b1a3db39228c45c14f8e07c48866ad3 158 PIRSF PIRSF009158 1 158 4.2E-94 T 28-03-2018 IPR016547 Uncharacterised conserved protein UCP009158 CP478_RS05010 6b1a3db39228c45c14f8e07c48866ad3 158 SUPERFAMILY SSF47598 71 148 8.0E-19 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS05010 6b1a3db39228c45c14f8e07c48866ad3 158 Gene3D G3DSA:1.20.5.780 71 150 2.8E-24 T 28-03-2018 CP478_RS05010 6b1a3db39228c45c14f8e07c48866ad3 158 Pfam PF08681 Protein of unknown function (DUF1778) 74 150 1.6E-24 T 28-03-2018 IPR014795 Vibrio phage ICP1, Orf50 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 Gene3D G3DSA:1.10.10.10 528 674 6.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 Gene3D G3DSA:1.20.1250.20 267 508 1.0E-26 T 28-03-2018 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 PRINTS PR01035 Tetracycline resistance protein signature 39 55 1.1E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 PRINTS PR01035 Tetracycline resistance protein signature 153 175 1.1E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 Pfam PF07690 Major Facilitator Superfamily 33 425 1.1E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 SUPERFAMILY SSF103473 22 211 1.24E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 SUPERFAMILY SSF103473 479 502 1.24E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 SUPERFAMILY SSF103473 263 435 1.24E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 SUPERFAMILY SSF46785 553 640 2.13E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10210 425f7b122ec35159b3980cac13794d24 687 Gene3D G3DSA:1.20.1250.20 21 212 1.7E-33 T 28-03-2018 CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 SUPERFAMILY SSF89963 91 163 9.68E-26 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 Gene3D G3DSA:3.30.70.990 12 97 1.1E-30 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 26.869 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 Gene3D G3DSA:3.30.70.860 98 163 3.0E-32 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 SUPERFAMILY SSF89963 5 89 4.18E-26 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CP478_RS03025 e6598d0b0036112f3fed22751ebeb280 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 3.5E-62 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CP478_RS05835 761de2501de13de375dd33a11c21bad0 360 Pfam PF01734 Patatin-like phospholipase 19 175 8.9E-15 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS05835 761de2501de13de375dd33a11c21bad0 360 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 22 54 - T 28-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 CP478_RS05835 761de2501de13de375dd33a11c21bad0 360 Gene3D G3DSA:3.40.1090.10 8 245 1.7E-33 T 28-03-2018 CP478_RS05835 761de2501de13de375dd33a11c21bad0 360 SUPERFAMILY SSF52151 251 337 1.54E-45 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS05835 761de2501de13de375dd33a11c21bad0 360 SUPERFAMILY SSF52151 14 191 1.54E-45 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:3.40.50.980 247 421 5.4E-31 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 SUPERFAMILY SSF47336 645 720 9.68E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 SMART SM01294 649 716 0.0086 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:2.30.38.10 425 500 2.8E-11 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Pfam PF00550 Phosphopantetheine attachment site 650 716 1.5E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 770 1167 1.0E-90 T 28-03-2018 IPR010080 Thioester reductase-like domain CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:3.30.300.30 502 624 1.8E-11 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:3.40.50.980 40 246 1.6E-30 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Pfam PF07993 Male sterility protein 773 1035 5.6E-57 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:1.10.1200.10 625 722 5.4E-16 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 SUPERFAMILY SSF56801 40 635 2.09E-89 T 28-03-2018 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 ProSitePatterns PS00455 Putative AMP-binding domain signature. 242 253 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Pfam PF00501 AMP-binding enzyme 82 507 2.0E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 SUPERFAMILY SSF51735 769 1079 5.39E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 SMART SM00823 Phosphopantetheine attachment site 648 720 8.2E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS14195 b6a9d74a62f67e803b5116af7ac80ff2 1168 Gene3D G3DSA:3.40.50.720 765 1117 2.3E-28 T 28-03-2018 CP478_RS07270 707e545cab69fe83158ede08f13a5cef 603 Pfam PF00934 PE family 1 93 2.1E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS07270 707e545cab69fe83158ede08f13a5cef 603 SUPERFAMILY SSF140459 8 84 1.44E-25 T 28-03-2018 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 Pfam PF04055 Radical SAM superfamily 82 239 1.8E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 Hamap MF_01694 Biotin synthase [bioB]. 35 343 37.67 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 SMART SM00876 250 342 6.0E-27 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 Gene3D G3DSA:3.20.20.70 26 334 8.5E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 PIRSF PIRSF001619 19 348 1.5E-105 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 SUPERFAMILY SSF102114 34 332 5.76E-67 T 28-03-2018 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 TIGRFAM TIGR00433 bioB: biotin synthase 47 340 8.4E-106 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 SMART SM00729 75 280 1.4E-35 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS08700 66f0e13567bf2b383509e1d84fa4ff0f 349 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 250 338 1.5E-11 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CP478_RS00790 0327cbb425770fab382bc76e95e3acd7 310 Pfam PF04072 Leucine carboxyl methyltransferase 18 204 3.3E-62 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS00790 0327cbb425770fab382bc76e95e3acd7 310 SUPERFAMILY SSF53335 14 293 5.81E-80 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS00790 0327cbb425770fab382bc76e95e3acd7 310 Gene3D G3DSA:3.40.50.150 1 291 1.3E-57 T 28-03-2018 CP478_RS00790 0327cbb425770fab382bc76e95e3acd7 310 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 288 6.5E-94 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 Pfam PF13180 PDZ domain 134 193 2.7E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 SUPERFAMILY SSF50156 133 237 1.05E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 Gene3D G3DSA:3.30.230.10 219 339 4.2E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 SUPERFAMILY SSF54211 224 328 6.07E-19 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 236 305 1.5E-8 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CP478_RS17495 2adb9a770da40141e26784574319b8d7 340 Gene3D G3DSA:2.30.42.10 130 218 2.3E-13 T 28-03-2018 CP478_RS16310 e40f18af77d15374b8de99191eb1927c 214 SUPERFAMILY SSF53448 14 208 2.45E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS16310 e40f18af77d15374b8de99191eb1927c 214 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 12 207 5.8E-61 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CP478_RS16310 e40f18af77d15374b8de99191eb1927c 214 Gene3D G3DSA:3.90.550.10 8 181 3.2E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS16310 e40f18af77d15374b8de99191eb1927c 214 Pfam PF01983 Guanylyl transferase CofC like 12 166 8.5E-13 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CP478_RS16310 e40f18af77d15374b8de99191eb1927c 214 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 10 214 23.247 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CP478_RS09175 8853641b04213fbf259fb8f96f00783e 274 SUPERFAMILY SSF53850 4 235 6.62E-21 T 28-03-2018 CP478_RS09175 8853641b04213fbf259fb8f96f00783e 274 Gene3D G3DSA:3.40.190.10 24 99 0.0039 T 28-03-2018 CP478_RS09175 8853641b04213fbf259fb8f96f00783e 274 Gene3D G3DSA:3.40.190.10 100 254 7.0E-18 T 28-03-2018 CP478_RS09175 8853641b04213fbf259fb8f96f00783e 274 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 35 256 1.3E-30 T 28-03-2018 CP478_RS08680 a707df72f57c8e89d211f06c5ecf2d0f 469 SUPERFAMILY SSF53041 8 155 4.58E-23 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS08680 a707df72f57c8e89d211f06c5ecf2d0f 469 Gene3D G3DSA:3.40.50.1390 3 161 3.5E-34 T 28-03-2018 CP478_RS08680 a707df72f57c8e89d211f06c5ecf2d0f 469 SMART SM00857 9 156 3.4E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS08680 a707df72f57c8e89d211f06c5ecf2d0f 469 Pfam PF00239 Resolvase, N terminal domain 9 154 2.7E-29 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS08680 a707df72f57c8e89d211f06c5ecf2d0f 469 Pfam PF07508 Recombinase 175 270 1.0E-11 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CP478_RS09390 df43a60878849174e654fa1f301d78ad 75 Gene3D G3DSA:1.10.1220.10 2 75 2.0E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS09390 df43a60878849174e654fa1f301d78ad 75 SUPERFAMILY SSF47598 3 59 8.53E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS15395 2d4a1c6c23493aa9b93a7c1cc8437ea2 270 Pfam PF13401 AAA domain 44 173 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS15395 2d4a1c6c23493aa9b93a7c1cc8437ea2 270 SUPERFAMILY SSF52540 9 266 1.37E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15395 2d4a1c6c23493aa9b93a7c1cc8437ea2 270 Gene3D G3DSA:3.40.50.300 29 169 2.8E-8 T 28-03-2018 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 Gene3D G3DSA:2.30.110.10 32 224 6.5E-57 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 SUPERFAMILY SSF50475 28 224 8.23E-58 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 PIRSF PIRSF000190 9 224 5.5E-70 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 35 214 7.8E-60 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 188 224 1.9E-13 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 21 224 33.191 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 50 134 5.6E-16 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS14285 880cb195f659b241621dd44fb21c4c7d 224 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 198 211 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS07555 cc4ff174bd18d2ef840d7f03fd752525 475 SMART SM00507 362 412 0.0023 T 28-03-2018 IPR003615 HNH nuclease CP478_RS07555 cc4ff174bd18d2ef840d7f03fd752525 475 Gene3D G3DSA:3.40.1800.10 353 423 2.3E-6 T 28-03-2018 CP478_RS07555 cc4ff174bd18d2ef840d7f03fd752525 475 Pfam PF02720 Domain of unknown function (DUF222) 71 328 2.3E-14 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS17115 2d55f270de1c7af89ee1fad29f617ad7 344 SUPERFAMILY SSF55469 227 319 1.57E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17115 2d55f270de1c7af89ee1fad29f617ad7 344 SUPERFAMILY SSF55469 2 89 1.57E-7 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS17115 2d55f270de1c7af89ee1fad29f617ad7 344 Gene3D G3DSA:3.40.109.10 1 320 1.5E-34 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 Pfam PF00582 Universal stress protein family 161 292 1.2E-27 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 Pfam PF00582 Universal stress protein family 10 148 1.7E-25 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 Gene3D G3DSA:3.40.50.620 5 150 7.4E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 PRINTS PR01438 Universal stress protein signature 158 176 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 PRINTS PR01438 Universal stress protein signature 252 264 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 PRINTS PR01438 Universal stress protein signature 270 292 4.3E-19 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 SUPERFAMILY SSF52402 160 293 1.09E-32 T 28-03-2018 CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 Gene3D G3DSA:3.40.50.620 151 292 2.4E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS11060 4846469edd0d1bf607535d982e506aa2 294 SUPERFAMILY SSF52402 10 149 1.59E-30 T 28-03-2018 CP478_RS15280 92cb28f680a0ce4b737923fcb53ddc1b 459 Pfam PF12323 Helix-turn-helix domain 11 48 1.7E-10 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CP478_RS15280 92cb28f680a0ce4b737923fcb53ddc1b 459 Pfam PF07282 Putative transposase DNA-binding domain 345 407 1.4E-14 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CP478_RS15280 92cb28f680a0ce4b737923fcb53ddc1b 459 Pfam PF01385 Probable transposase 205 320 8.4E-29 T 28-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CP478_RS08590 cb51d089c5274ef25fd955a1c026842a 386 Gene3D G3DSA:3.40.640.10 50 282 8.7E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS08590 cb51d089c5274ef25fd955a1c026842a 386 SUPERFAMILY SSF53383 32 381 1.32E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS08590 cb51d089c5274ef25fd955a1c026842a 386 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CP478_RS08590 cb51d089c5274ef25fd955a1c026842a 386 Gene3D G3DSA:3.90.1150.10 283 386 5.9E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS08590 cb51d089c5274ef25fd955a1c026842a 386 Pfam PF00155 Aminotransferase class I and II 43 373 1.6E-56 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS18125 e4f747846abddc98682931765aeefee9 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 41.445 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CP478_RS18125 e4f747846abddc98682931765aeefee9 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 205 1.7E-62 T 28-03-2018 CP478_RS18125 e4f747846abddc98682931765aeefee9 207 SUPERFAMILY SSF53271 3 205 1.02E-60 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS18125 e4f747846abddc98682931765aeefee9 207 Gene3D G3DSA:3.40.50.2020 1 205 1.3E-60 T 28-03-2018 CP478_RS18125 e4f747846abddc98682931765aeefee9 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 2 206 5.5E-78 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 SUPERFAMILY SSF46785 103 175 8.39E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 23 185 1.1E-32 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 SUPERFAMILY SSF46785 19 98 9.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 Pfam PF04079 Segregation and condensation complex subunit ScpB 27 183 5.8E-49 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 PIRSF PIRSF019345 9 223 1.1E-62 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 Gene3D G3DSA:1.10.10.10 104 174 9.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09330 0b5fa851e3fe3e0982180ef9ed4b9546 227 Gene3D G3DSA:1.10.10.10 12 103 2.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13980 90b414bd00ce1aa804691b4741f0bbc9 81 Pfam PF01402 Ribbon-helix-helix protein, copG family 11 49 3.3E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS13980 90b414bd00ce1aa804691b4741f0bbc9 81 Gene3D G3DSA:1.10.1220.10 8 50 1.1E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS08360 93e6c12d38d060e9fab83d01ad899042 414 SUPERFAMILY SSF53756 1 413 5.58E-88 T 28-03-2018 CP478_RS08360 93e6c12d38d060e9fab83d01ad899042 414 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 85 1.5E-8 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CP478_RS08360 93e6c12d38d060e9fab83d01ad899042 414 Gene3D G3DSA:3.40.50.2000 250 400 2.1E-25 T 28-03-2018 CP478_RS08360 93e6c12d38d060e9fab83d01ad899042 414 Gene3D G3DSA:3.40.50.2000 1 249 8.0E-36 T 28-03-2018 CP478_RS20975 2ed71afd2f64298c660c0874b2c53328 137 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 20 94 1.2E-16 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS07540 df7b069799511d8c440743bc83302886 439 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 66 435 6.0E-154 T 28-03-2018 IPR003776 YcaO-like domain CP478_RS07540 df7b069799511d8c440743bc83302886 439 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 115 423 1.5E-56 T 28-03-2018 IPR003776 YcaO-like domain CP478_RS01260 5780a891105d0e13bff071bbf0997534 314 SUPERFAMILY SSF47240 20 280 1.04E-51 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS01260 5780a891105d0e13bff071bbf0997534 314 Gene3D G3DSA:1.10.620.20 1 290 6.7E-63 T 28-03-2018 CP478_RS01260 5780a891105d0e13bff071bbf0997534 314 Pfam PF00268 Ribonucleotide reductase, small chain 28 272 2.5E-18 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS08395 e5ce3ed562e2b7e7c15690d0f2759d3e 188 SUPERFAMILY SSF69118 4 176 7.68E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS08395 e5ce3ed562e2b7e7c15690d0f2759d3e 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 122 1.6E-16 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS08395 e5ce3ed562e2b7e7c15690d0f2759d3e 188 Gene3D G3DSA:1.20.1290.10 29 179 2.5E-28 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 SUPERFAMILY SSF56762 48 440 1.57E-119 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 75 86 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 155 440 6.3E-109 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 Gene3D G3DSA:1.10.645.10 34 236 8.3E-49 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 27 440 46.515 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 Gene3D G3DSA:1.10.645.10 237 436 2.4E-41 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17240 4ef4f4939b2540a6fc2677b56d745fa3 440 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 38 440 1.1E-185 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 328 342 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 454 466 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 406 420 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 368 383 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 475 492 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 558 570 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 420 439 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 PRINTS PR00819 CbxX/CfqX superfamily signature 492 511 2.0E-46 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 SUPERFAMILY SSF52540 339 593 1.22E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 369 504 8.3E-19 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 SMART SM00382 365 507 8.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 Gene3D G3DSA:3.40.50.300 299 503 2.4E-21 T 28-03-2018 CP478_RS21230 ae1e87d08b6453fe592f5a59a85b383e 619 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 37 609 2.6E-231 T 28-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA CP478_RS05725 99964299c305f8a992baa0472b8b4571 293 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 49 278 3.6E-16 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 Pfam PF04389 Peptidase family M28 252 471 4.0E-47 T 28-03-2018 IPR007484 Peptidase M28 CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 SUPERFAMILY SSF52025 131 249 9.94E-14 T 28-03-2018 CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 SUPERFAMILY SSF53187 236 478 5.57E-59 T 28-03-2018 CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 SUPERFAMILY SSF53187 48 101 5.57E-59 T 28-03-2018 CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 Gene3D G3DSA:3.40.630.10 49 481 7.6E-57 T 28-03-2018 CP478_RS02230 9a2eb90974b1864d64924bd2415f6bdb 500 Pfam PF02225 PA domain 140 229 6.3E-14 T 28-03-2018 IPR003137 PA domain CP478_RS07600 86d9e431cdd3c1a570868d352e7befe7 539 SUPERFAMILY SSF140459 5 176 5.23E-55 T 28-03-2018 CP478_RS07600 86d9e431cdd3c1a570868d352e7befe7 539 Gene3D G3DSA:1.10.287.1060 29 112 5.4E-4 T 28-03-2018 CP478_RS07600 86d9e431cdd3c1a570868d352e7befe7 539 Pfam PF00823 PPE family 7 163 9.8E-52 T 28-03-2018 IPR000030 PPE family CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 Gene3D G3DSA:3.60.120.10 100 466 1.5E-93 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 PRINTS PR00095 Anthranilate synthase component I signature 302 315 1.4E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 PRINTS PR00095 Anthranilate synthase component I signature 316 329 1.4E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 PRINTS PR00095 Anthranilate synthase component I signature 411 425 1.4E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 PRINTS PR00095 Anthranilate synthase component I signature 396 410 1.4E-10 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 SUPERFAMILY SSF56322 46 461 2.62E-91 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 Pfam PF00425 chorismate binding enzyme 208 455 5.4E-67 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CP478_RS05500 3e34a0ea421c1a8476d5cb891ff4fd43 478 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 129 459 8.4E-119 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 SUPERFAMILY SSF46689 24 88 1.85E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 81 2.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 Gene3D G3DSA:1.10.357.10 23 212 2.6E-24 T 28-03-2018 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 8.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 8.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS04175 69a1847775c8c19666182bf04e28f275 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 47 78 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Gene3D G3DSA:3.40.228.10 141 413 1.2E-51 T 28-03-2018 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Pfam PF01568 Molydopterin dinucleotide binding domain 623 739 3.6E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 SUPERFAMILY SSF50692 616 764 2.1E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Gene3D G3DSA:2.40.40.20 597 760 3.0E-32 T 28-03-2018 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Gene3D G3DSA:3.90.55.10 2 86 5.6E-11 T 28-03-2018 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Gene3D G3DSA:3.90.55.10 474 557 4.9E-21 T 28-03-2018 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 Pfam PF00384 Molybdopterin oxidoreductase 50 510 1.1E-55 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 SUPERFAMILY SSF53706 6 625 6.67E-151 T 28-03-2018 CP478_RS07900 cd1c0776c422818ea511cb48fd1d372b 766 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 7 764 0.0 T 28-03-2018 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 SUPERFAMILY SSF51735 7 167 8.17E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 290 5.0E-39 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 290 8.3E-91 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 246 268 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 PIRSF PIRSF000193 237 293 2.5E-8 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 PIRSF PIRSF000193 5 232 5.6E-53 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 106 1.3E-24 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 SUPERFAMILY SSF48179 168 290 4.42E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 Gene3D G3DSA:3.40.50.720 5 170 4.6E-28 T 28-03-2018 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 290 26.927 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CP478_RS02670 5ea4cf3526c6db72eb54396d42770304 295 Gene3D G3DSA:1.10.3730.10 171 293 3.4E-42 T 28-03-2018 CP478_RS10040 48b313266bb75cd1465d2d5084722b80 138 SUPERFAMILY SSF46785 4 123 1.98E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10040 48b313266bb75cd1465d2d5084722b80 138 Pfam PF03965 Penicillinase repressor 7 120 5.5E-29 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CP478_RS10040 48b313266bb75cd1465d2d5084722b80 138 Gene3D G3DSA:1.10.10.10 8 71 7.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10040 48b313266bb75cd1465d2d5084722b80 138 PIRSF PIRSF019455 1 131 2.3E-21 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CP478_RS15965 c8b1be6ca1e0fd238a483ec176362a53 93 Pfam PF00708 Acylphosphatase 9 91 1.4E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CP478_RS15965 c8b1be6ca1e0fd238a483ec176362a53 93 Gene3D G3DSA:3.30.70.100 1 93 1.2E-25 T 28-03-2018 CP478_RS15965 c8b1be6ca1e0fd238a483ec176362a53 93 SUPERFAMILY SSF54975 5 91 1.7E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CP478_RS15965 c8b1be6ca1e0fd238a483ec176362a53 93 ProSitePatterns PS00151 Acylphosphatase signature 2. 36 52 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CP478_RS15965 c8b1be6ca1e0fd238a483ec176362a53 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CP478_RS15770 3e00dcc07c02e2f5914983de61373f06 459 Pfam PF01385 Probable transposase 205 320 7.7E-27 T 28-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CP478_RS15770 3e00dcc07c02e2f5914983de61373f06 459 Pfam PF07282 Putative transposase DNA-binding domain 345 407 3.5E-14 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CP478_RS15770 3e00dcc07c02e2f5914983de61373f06 459 Pfam PF12323 Helix-turn-helix domain 13 44 2.1E-8 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CP478_RS20495 4ae20836d74a49e41c0c8f430db2600a 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 102 6.8E-23 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CP478_RS20495 4ae20836d74a49e41c0c8f430db2600a 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CP478_RS20495 4ae20836d74a49e41c0c8f430db2600a 152 Gene3D G3DSA:3.40.140.10 1 151 1.5E-42 T 28-03-2018 CP478_RS20495 4ae20836d74a49e41c0c8f430db2600a 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 150 44.743 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CP478_RS20495 4ae20836d74a49e41c0c8f430db2600a 152 SUPERFAMILY SSF53927 3 150 2.84E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS17070 0ae863192bc784ce56d8823af4dfc9b7 147 Pfam PF02391 MoaE protein 15 127 4.2E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS17070 0ae863192bc784ce56d8823af4dfc9b7 147 SUPERFAMILY SSF54690 11 146 9.94E-45 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS17070 0ae863192bc784ce56d8823af4dfc9b7 147 Gene3D G3DSA:3.90.1170.40 1 147 8.7E-50 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS00760 ece0212fdb78dd0ac92c0461699375d8 126 Pfam PF04248 Domain of unknown function (DUF427) 24 116 4.2E-30 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CP478_RS12630 fc3eb0b9333b1057155341507b0d7286 290 SUPERFAMILY SSF161098 53 274 1.57E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS12630 fc3eb0b9333b1057155341507b0d7286 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 280 3.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS12630 fc3eb0b9333b1057155341507b0d7286 290 Gene3D G3DSA:1.20.58.370 4 43 2.1E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CP478_RS12630 fc3eb0b9333b1057155341507b0d7286 290 Gene3D G3DSA:1.10.3720.10 59 286 4.8E-47 T 28-03-2018 CP478_RS09210 7e7250758dd98c9f891a882fd1ab46b9 255 Pfam PF00005 ABC transporter 33 170 3.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS09210 7e7250758dd98c9f891a882fd1ab46b9 255 SMART SM00382 42 217 6.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09210 7e7250758dd98c9f891a882fd1ab46b9 255 Gene3D G3DSA:3.40.50.300 14 248 7.6E-59 T 28-03-2018 CP478_RS09210 7e7250758dd98c9f891a882fd1ab46b9 255 SUPERFAMILY SSF52540 16 232 2.72E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09210 7e7250758dd98c9f891a882fd1ab46b9 255 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS06480 b41330c27927579701a973719371f6a5 472 Pfam PF00668 Condensation domain 55 468 1.5E-18 T 28-03-2018 IPR001242 Condensation domain CP478_RS06480 b41330c27927579701a973719371f6a5 472 Gene3D G3DSA:3.30.559.10 19 229 2.9E-8 T 28-03-2018 CP478_RS06480 b41330c27927579701a973719371f6a5 472 SUPERFAMILY SSF52777 43 213 2.0E-16 T 28-03-2018 CP478_RS06480 b41330c27927579701a973719371f6a5 472 SUPERFAMILY SSF52777 233 467 1.07E-24 T 28-03-2018 CP478_RS07445 19535d6ca20b0f575460ac460b7d0120 307 SMART SM00052 53 304 1.2E-114 T 28-03-2018 IPR001633 EAL domain CP478_RS07445 19535d6ca20b0f575460ac460b7d0120 307 Gene3D G3DSA:3.20.20.450 52 307 2.0E-85 T 28-03-2018 IPR001633 EAL domain CP478_RS07445 19535d6ca20b0f575460ac460b7d0120 307 Pfam PF00563 EAL domain 61 298 4.6E-65 T 28-03-2018 IPR001633 EAL domain CP478_RS07445 19535d6ca20b0f575460ac460b7d0120 307 SUPERFAMILY SSF141868 60 305 7.59E-73 T 28-03-2018 IPR001633 EAL domain CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Gene3D G3DSA:3.40.50.720 4 159 2.5E-32 T 28-03-2018 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 SUPERFAMILY SSF51735 5 160 2.04E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 SUPERFAMILY SSF55021 353 431 7.08E-10 T 28-03-2018 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Gene3D G3DSA:3.30.360.10 160 305 6.2E-51 T 28-03-2018 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Pfam PF01842 ACT domain 355 424 1.8E-10 T 28-03-2018 IPR002912 ACT domain CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 14 131 3.0E-22 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Pfam PF00742 Homoserine dehydrogenase 139 322 1.2E-65 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 Gene3D G3DSA:3.30.70.260 351 435 1.1E-19 T 28-03-2018 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 PIRSF PIRSF000098 5 439 1.7E-152 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CP478_RS07080 1abbef311d4e05c8092721dcb4a78a01 441 SUPERFAMILY SSF55347 139 309 7.85E-50 T 28-03-2018 CP478_RS00265 8b65294d1f4110c83e27575188a50227 289 Pfam PF08044 Domain of unknown function (DUF1707) 17 69 7.0E-17 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CP478_RS11490 af33caf71d0e0c14de54fac9bffc3822 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 1.5E-21 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CP478_RS11490 af33caf71d0e0c14de54fac9bffc3822 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.856 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CP478_RS11490 af33caf71d0e0c14de54fac9bffc3822 64 Pfam PF05639 Pup-like protein 3 64 2.1E-22 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CP478_RS16480 15add7bec83d590316e71e4d9bcd29ac 218 SUPERFAMILY SSF55021 3 71 2.29E-6 T 28-03-2018 CP478_RS16480 15add7bec83d590316e71e4d9bcd29ac 218 Gene3D G3DSA:3.30.70.260 1 120 1.5E-7 T 28-03-2018 CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 PIRSF PIRSF000355 4 321 3.4E-80 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 Gene3D G3DSA:1.10.620.20 5 297 1.1E-78 T 28-03-2018 CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 Pfam PF00268 Ribonucleotide reductase, small chain 14 285 3.7E-88 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 12 324 5.8E-146 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 SUPERFAMILY SSF47240 10 324 1.62E-105 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS16675 a561ba84730636c0991d39a936045ce8 324 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 102 118 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CP478_RS03255 9d10187059fe014cc5ba2434b49222d1 133 SUPERFAMILY SSF88723 1 128 6.21E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03255 9d10187059fe014cc5ba2434b49222d1 133 Gene3D G3DSA:3.40.50.1010 1 130 1.4E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03255 9d10187059fe014cc5ba2434b49222d1 133 Pfam PF01850 PIN domain 1 124 1.2E-14 T 28-03-2018 IPR002716 PIN domain CP478_RS03255 9d10187059fe014cc5ba2434b49222d1 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 131 14.14 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 SUPERFAMILY SSF52172 21 195 1.71E-42 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 Gene3D G3DSA:1.10.10.10 140 248 2.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 SMART SM00448 23 134 4.3E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 Pfam PF00072 Response regulator receiver domain 25 134 1.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 Gene3D G3DSA:3.40.50.2300 18 139 7.6E-37 T 28-03-2018 CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 Pfam PF00486 Transcriptional regulatory protein, C terminal 168 242 2.2E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS03220 1b85718cd848fbb17a63ac05e3c0b0f8 253 SMART SM00862 167 242 1.9E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS01970 10e0d8c6c5b77b674df5928cfc677016 200 SUPERFAMILY SSF55961 1 146 1.39E-33 T 28-03-2018 CP478_RS01970 10e0d8c6c5b77b674df5928cfc677016 200 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 145 4.3E-21 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G CP478_RS01970 10e0d8c6c5b77b674df5928cfc677016 200 Gene3D G3DSA:3.30.530.20 1 160 1.6E-19 T 28-03-2018 IPR023393 START-like domain CP478_RS14050 ab205429111e59af7d0edcf4d8658137 245 ProDom PD066345 MB2591 RV2561/RV2562/MT2638 34 245 2.0E-123 T 28-03-2018 IPR020503 Uncharacterised protein family Rv2561 CP478_RS14050 ab205429111e59af7d0edcf4d8658137 245 Pfam PF10851 Protein of unknown function (DUF2652) 34 149 5.4E-45 T 28-03-2018 IPR020503 Uncharacterised protein family Rv2561 CP478_RS12800 2fb11e4338031dc1dc40980667c3009f 94 PIRSF PIRSF037656 1 94 1.1E-58 T 28-03-2018 IPR009416 ESAT-6-like protein, Mycobacterium CP478_RS12800 2fb11e4338031dc1dc40980667c3009f 94 Gene3D G3DSA:1.10.287.1060 1 94 3.0E-12 T 28-03-2018 CP478_RS12800 2fb11e4338031dc1dc40980667c3009f 94 SUPERFAMILY SSF140453 2 93 2.22E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS12800 2fb11e4338031dc1dc40980667c3009f 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 7.0E-14 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS12825 7271fd65dea453c472e23d7ecc1549d5 512 Gene3D G3DSA:3.40.720.10 314 430 8.9E-7 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS12825 7271fd65dea453c472e23d7ecc1549d5 512 Gene3D G3DSA:3.40.720.10 51 298 0.012 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS12825 7271fd65dea453c472e23d7ecc1549d5 512 Pfam PF04185 Phosphoesterase family 43 423 1.1E-128 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CP478_RS10090 f87bdc666cd1c0a40571ba85d0303770 225 SUPERFAMILY SSF51735 5 222 3.08E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10090 f87bdc666cd1c0a40571ba85d0303770 225 Gene3D G3DSA:3.40.50.720 133 221 5.3E-8 T 28-03-2018 CP478_RS10090 f87bdc666cd1c0a40571ba85d0303770 225 Gene3D G3DSA:3.40.50.720 4 132 1.1E-15 T 28-03-2018 CP478_RS10090 f87bdc666cd1c0a40571ba85d0303770 225 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 219 1.6E-17 T 28-03-2018 CP478_RS19045 6055bf7abc8d144b4d7e1abe6ff28bce 260 Pfam PF10708 Protein of unknown function (DUF2510) 11 43 8.9E-12 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 CP478_RS00735 b78f8ce4528a04ac3bb991009020b748 201 Gene3D G3DSA:1.10.357.10 13 201 2.1E-26 T 28-03-2018 CP478_RS00735 b78f8ce4528a04ac3bb991009020b748 201 SUPERFAMILY SSF46689 14 91 1.44E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00735 b78f8ce4528a04ac3bb991009020b748 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01605 6e5fce03b4c080379377e24659d24f47 75 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 4.2E-10 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS01605 6e5fce03b4c080379377e24659d24f47 75 Gene3D G3DSA:1.10.1220.10 1 41 1.1E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS09420 81e6d8ddc5a5ffd7d0fb47ae0c71375b 189 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 130 9.9E-13 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS09420 81e6d8ddc5a5ffd7d0fb47ae0c71375b 189 SUPERFAMILY SSF109854 5 135 6.1E-18 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS09420 81e6d8ddc5a5ffd7d0fb47ae0c71375b 189 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 186 5.0E-59 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CP478_RS09420 81e6d8ddc5a5ffd7d0fb47ae0c71375b 189 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 186 1.4E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS09420 81e6d8ddc5a5ffd7d0fb47ae0c71375b 189 Gene3D G3DSA:1.20.120.450 2 136 1.9E-17 T 28-03-2018 CP478_RS17805 edfa06dc8cf2089b8747b39d04b14a06 214 SUPERFAMILY SSF52540 2 198 1.54E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17805 edfa06dc8cf2089b8747b39d04b14a06 214 ProSitePatterns PS01331 Thymidylate kinase signature. 92 104 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CP478_RS17805 edfa06dc8cf2089b8747b39d04b14a06 214 Gene3D G3DSA:3.40.50.300 1 207 4.5E-32 T 28-03-2018 CP478_RS17805 edfa06dc8cf2089b8747b39d04b14a06 214 Pfam PF02223 Thymidylate kinase 5 187 3.8E-22 T 28-03-2018 CP478_RS02625 901245aa798710b9c186785575a19727 629 SUPERFAMILY SSF51905 145 406 2.87E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02625 901245aa798710b9c186785575a19727 629 SUPERFAMILY SSF51905 562 623 2.87E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02625 901245aa798710b9c186785575a19727 629 Pfam PF00732 GMC oxidoreductase 148 408 2.4E-53 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS02625 901245aa798710b9c186785575a19727 629 Pfam PF05199 GMC oxidoreductase 497 615 7.9E-17 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CP478_RS02625 901245aa798710b9c186785575a19727 629 Gene3D G3DSA:3.50.50.60 136 625 1.1E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS02625 901245aa798710b9c186785575a19727 629 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 380 394 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 SUPERFAMILY SSF46689 6 82 1.45E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 SUPERFAMILY SSF48498 85 187 7.31E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 Gene3D G3DSA:1.10.357.10 67 189 1.2E-14 T 28-03-2018 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 Gene3D G3DSA:1.10.260.40 42 66 1.9E-13 T 28-03-2018 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00375 039bcb118d453ecf057fc774493f8926 189 Gene3D G3DSA:1.10.10.60 2 41 9.9E-14 T 28-03-2018 CP478_RS07010 9eec35e03ed7cbe6001323c2e0e819f5 291 SUPERFAMILY SSF161098 78 266 8.01E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07010 9eec35e03ed7cbe6001323c2e0e819f5 291 Gene3D G3DSA:1.10.3720.10 6 272 2.5E-32 T 28-03-2018 CP478_RS07010 9eec35e03ed7cbe6001323c2e0e819f5 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 282 7.1E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07010 9eec35e03ed7cbe6001323c2e0e819f5 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 58 3.9E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CP478_RS07380 7024300bb7319935dad93f14b560f7a0 210 SMART SM01006 46 92 7.7E-15 T 28-03-2018 IPR019432 Siderophore biosynthesis protein, conserved domain CP478_RS07380 7024300bb7319935dad93f14b560f7a0 210 SUPERFAMILY SSF55729 15 204 2.53E-56 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS07380 7024300bb7319935dad93f14b560f7a0 210 Gene3D G3DSA:3.40.630.30 1 210 8.3E-25 T 28-03-2018 CP478_RS07380 7024300bb7319935dad93f14b560f7a0 210 Pfam PF13523 Acetyltransferase (GNAT) domain 51 191 3.0E-44 T 28-03-2018 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 Gene3D G3DSA:3.90.1150.10 193 266 2.5E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 Gene3D G3DSA:3.90.1150.10 267 448 3.8E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 Gene3D G3DSA:3.90.1150.10 3 192 6.4E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 Pfam PF00202 Aminotransferase class-III 30 442 3.7E-93 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 PIRSF PIRSF000521 32 447 3.2E-24 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS18235 a38a3c89a543c5520f3c3fb1fb6b170d 455 SUPERFAMILY SSF53383 22 446 2.06E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS13190 38a0301606c852fe349ca63eab240971 408 SUPERFAMILY SSF55718 306 402 1.08E-19 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Pfam PF13530 Sterol carrier protein domain 193 400 7.9E-40 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Gene3D G3DSA:3.40.630.30 142 294 9.9E-37 T 28-03-2018 CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Gene3D G3DSA:3.30.1050.10 295 401 8.9E-23 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS13190 38a0301606c852fe349ca63eab240971 408 SUPERFAMILY SSF55729 11 304 6.57E-52 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Gene3D G3DSA:3.40.630.30 6 141 3.5E-15 T 28-03-2018 CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Pfam PF13527 Acetyltransferase (GNAT) domain 13 139 3.8E-24 T 28-03-2018 CP478_RS13190 38a0301606c852fe349ca63eab240971 408 Hamap MF_01812 UPF0256 protein . 8 408 33.102 T 28-03-2018 IPR022902 N-acetyltransferase Eis CP478_RS09725 39680518a037c864f1401569189b7813 67 SUPERFAMILY SSF54862 2 62 3.35E-9 T 28-03-2018 CP478_RS09725 39680518a037c864f1401569189b7813 67 Gene3D G3DSA:3.30.70.20 1 64 2.1E-6 T 28-03-2018 CP478_RS09725 39680518a037c864f1401569189b7813 67 Pfam PF13459 4Fe-4S single cluster domain 3 60 3.5E-12 T 28-03-2018 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 245 7.3E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 27 141 3.9E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 262 409 1.8E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 SUPERFAMILY SSF56645 13 271 6.41E-64 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Gene3D G3DSA:1.20.140.10 247 419 3.0E-35 T 28-03-2018 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 SUPERFAMILY SSF47203 256 415 2.58E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Gene3D G3DSA:1.10.540.10 13 144 1.4E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS00715 0ff6ddd41c9da29b78570cf46ef14072 447 Gene3D G3DSA:2.40.110.10 145 246 2.0E-32 T 28-03-2018 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 229 1.2E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 SUPERFAMILY SSF56645 10 239 3.53E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Gene3D G3DSA:1.20.140.10 233 394 4.6E-35 T 28-03-2018 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 SUPERFAMILY SSF47203 245 391 3.87E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 386 7.0E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 135 2.1E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Gene3D G3DSA:2.40.110.10 138 232 4.3E-35 T 28-03-2018 CP478_RS02135 0f8553cf8de23a75dbe05c1f417136d6 395 Gene3D G3DSA:1.10.540.10 2 137 5.4E-33 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS10220 96accd6ffddc81adb349bf57f20ab141 378 SUPERFAMILY SSF51556 147 375 5.76E-13 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS10220 96accd6ffddc81adb349bf57f20ab141 378 SUPERFAMILY SSF51556 17 120 5.76E-13 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS10220 96accd6ffddc81adb349bf57f20ab141 378 Pfam PF04909 Amidohydrolase 216 375 1.7E-12 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS10220 96accd6ffddc81adb349bf57f20ab141 378 Gene3D G3DSA:3.20.20.140 5 378 6.7E-62 T 28-03-2018 CP478_RS10745 687db54cab1ac36a5011bbf58e14b5ce 125 Pfam PF05305 Protein of unknown function (DUF732) 20 110 2.4E-16 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS21255 79aa1f61c464a3b5ca639a815b758263 276 Pfam PF14011 EspG family 5 257 4.5E-36 T 28-03-2018 IPR025734 EspG family CP478_RS00615 fb6ffb201af31f68a35923e726a38727 318 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 304 1.1E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00615 fb6ffb201af31f68a35923e726a38727 318 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS00615 fb6ffb201af31f68a35923e726a38727 318 Gene3D G3DSA:3.40.50.720 1 168 9.7E-28 T 28-03-2018 CP478_RS00615 fb6ffb201af31f68a35923e726a38727 318 Gene3D G3DSA:3.90.25.10 169 314 9.8E-23 T 28-03-2018 CP478_RS00615 fb6ffb201af31f68a35923e726a38727 318 SUPERFAMILY SSF51735 1 311 1.29E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 SUPERFAMILY SSF52402 150 271 3.1E-10 T 28-03-2018 CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 SUPERFAMILY SSF52402 9 143 1.76E-24 T 28-03-2018 CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 Gene3D G3DSA:3.40.50.620 2 140 3.0E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 Gene3D G3DSA:3.40.50.620 141 271 7.3E-9 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 Pfam PF00582 Universal stress protein family 9 140 7.5E-20 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 PRINTS PR01438 Universal stress protein signature 9 27 1.3E-11 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 PRINTS PR01438 Universal stress protein signature 100 112 1.3E-11 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS14375 ad65181fa8ac69aec36f939cabd47a23 272 PRINTS PR01438 Universal stress protein signature 118 140 1.3E-11 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS12020 b2cfcdce231d8cad72e2f43bd4976765 378 SUPERFAMILY SSF55073 208 364 8.95E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS12020 b2cfcdce231d8cad72e2f43bd4976765 378 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 207 350 1.7E-15 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS12020 b2cfcdce231d8cad72e2f43bd4976765 378 Gene3D G3DSA:3.30.70.1230 200 369 2.2E-31 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS12020 b2cfcdce231d8cad72e2f43bd4976765 378 Pfam PF16701 Adenylate cyclase regulatory domain 19 185 7.7E-9 T 28-03-2018 IPR032026 Adenylate cyclase regulatory domain CP478_RS12020 b2cfcdce231d8cad72e2f43bd4976765 378 SMART SM00044 159 345 2.8E-5 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS20730 6e6abcc070a0005f85e2fcbe1ee6d2a0 1098 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 25 688 2.8E-281 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CP478_RS20730 6e6abcc070a0005f85e2fcbe1ee6d2a0 1098 Gene3D G3DSA:2.60.120.610 46 220 1.4E-61 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CP478_RS20730 6e6abcc070a0005f85e2fcbe1ee6d2a0 1098 Pfam PF14896 EmbC C-terminal domain 719 1095 4.8E-136 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CP478_RS10715 84625a8385fced8be870063b954b1268 410 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 91 107 6.6E-19 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10715 84625a8385fced8be870063b954b1268 410 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 176 194 6.6E-19 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10715 84625a8385fced8be870063b954b1268 410 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 6.6E-19 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10715 84625a8385fced8be870063b954b1268 410 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 127 151 6.6E-19 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10715 84625a8385fced8be870063b954b1268 410 Pfam PF02470 MlaD protein 39 113 2.9E-16 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS10715 84625a8385fced8be870063b954b1268 410 SUPERFAMILY SSF58104 149 292 2.62E-6 T 28-03-2018 CP478_RS10715 84625a8385fced8be870063b954b1268 410 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 292 2.7E-82 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10715 84625a8385fced8be870063b954b1268 410 Gene3D G3DSA:3.90.20.10 133 297 9.3E-4 T 28-03-2018 CP478_RS05815 e19a8d4e20ce7e32cb44d597d63e0608 354 Gene3D G3DSA:3.40.50.720 5 126 4.4E-19 T 28-03-2018 CP478_RS05815 e19a8d4e20ce7e32cb44d597d63e0608 354 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 11 97 3.4E-6 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CP478_RS05815 e19a8d4e20ce7e32cb44d597d63e0608 354 SUPERFAMILY SSF51735 3 131 2.79E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Gene3D G3DSA:3.30.300.30 430 534 4.0E-26 T 28-03-2018 CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 519 1.7E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Gene3D G3DSA:3.40.50.980 23 193 1.8E-41 T 28-03-2018 CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 SUPERFAMILY SSF56801 24 529 1.02E-149 T 28-03-2018 CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Gene3D G3DSA:3.40.50.980 194 349 5.5E-39 T 28-03-2018 CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Gene3D G3DSA:2.30.38.10 350 429 3.5E-30 T 28-03-2018 CP478_RS00915 9921a37bd0fd72ddcdb6601870c829b9 554 Pfam PF00501 AMP-binding enzyme 32 436 1.3E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS07260 bf77f874da332ad05826302795503e82 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 1.0E-42 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 Gene3D G3DSA:3.40.47.10 1 265 3.2E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07260 bf77f874da332ad05826302795503e82 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 3.7E-96 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 PIRSF PIRSF000429 2 393 4.7E-112 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 SUPERFAMILY SSF53901 5 270 6.43E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07260 bf77f874da332ad05826302795503e82 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 Gene3D G3DSA:3.40.47.10 266 390 7.8E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07260 bf77f874da332ad05826302795503e82 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.5E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CP478_RS07260 bf77f874da332ad05826302795503e82 393 SUPERFAMILY SSF53901 272 390 3.69E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS05375 fb701a2a28ded52b463fac5299a9fba0 181 SUPERFAMILY SSF53218 27 177 6.02E-32 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05375 fb701a2a28ded52b463fac5299a9fba0 181 SMART SM00852 28 172 4.5E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05375 fb701a2a28ded52b463fac5299a9fba0 181 Gene3D G3DSA:3.40.980.10 23 180 8.9E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05375 fb701a2a28ded52b463fac5299a9fba0 181 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 27 165 8.3E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS05375 fb701a2a28ded52b463fac5299a9fba0 181 Pfam PF00994 Probable molybdopterin binding domain 30 167 5.5E-24 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS09590 5be0d2741d03a79d852353375c73e6ab 502 SUPERFAMILY SSF52777 38 201 1.87E-15 T 28-03-2018 CP478_RS09590 5be0d2741d03a79d852353375c73e6ab 502 Pfam PF06974 Protein of unknown function (DUF1298) 339 486 3.0E-30 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS09590 5be0d2741d03a79d852353375c73e6ab 502 Gene3D G3DSA:3.30.559.10 25 265 1.4E-9 T 28-03-2018 CP478_RS09590 5be0d2741d03a79d852353375c73e6ab 502 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 38 488 7.2E-138 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS09590 5be0d2741d03a79d852353375c73e6ab 502 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 38 298 2.4E-87 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS07130 709a62190d8c677bb522e567675163ae 217 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 208 7.1E-67 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CP478_RS07130 709a62190d8c677bb522e567675163ae 217 Gene3D G3DSA:3.90.870.10 1 213 2.1E-67 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS07130 709a62190d8c677bb522e567675163ae 217 Pfam PF01300 Telomere recombination 23 197 1.2E-44 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CP478_RS07130 709a62190d8c677bb522e567675163ae 217 SUPERFAMILY SSF55821 4 208 4.88E-55 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CP478_RS02535 e4004100c90df956f57f2b6192bb186e 199 SUPERFAMILY SSF58113 27 107 2.62E-5 T 28-03-2018 CP478_RS02535 e4004100c90df956f57f2b6192bb186e 199 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 2 159 3.0E-62 T 28-03-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 CP478_RS02535 e4004100c90df956f57f2b6192bb186e 199 Gene3D G3DSA:1.20.120.20 24 199 1.7E-7 T 28-03-2018 CP478_RS08600 c625d04daa9c22bca5db7086f0ad6311 169 Gene3D G3DSA:3.90.1140.10 2 163 1.2E-12 T 28-03-2018 CP478_RS08600 c625d04daa9c22bca5db7086f0ad6311 169 SUPERFAMILY SSF55144 1 129 3.79E-9 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CP478_RS08600 c625d04daa9c22bca5db7086f0ad6311 169 Pfam PF13563 2'-5' RNA ligase superfamily 28 134 4.1E-7 T 28-03-2018 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 Gene3D G3DSA:1.10.8.60 124 199 5.5E-12 T 28-03-2018 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 Pfam PF06144 DNA polymerase III, delta subunit 2 164 1.4E-7 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 Gene3D G3DSA:3.40.50.300 1 118 4.0E-7 T 28-03-2018 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 Gene3D G3DSA:1.20.272.10 200 313 6.9E-22 T 28-03-2018 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 SUPERFAMILY SSF48019 194 308 1.87E-12 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CP478_RS13175 a89d3f4fbe0059c11981275ad255aa48 316 SUPERFAMILY SSF52540 46 172 7.26E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.7E-15 T 28-03-2018 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 2.7E-15 T 28-03-2018 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 2.7E-15 T 28-03-2018 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 SUPERFAMILY SSF51905 239 308 1.78E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 SUPERFAMILY SSF51905 5 155 1.78E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 Pfam PF01494 FAD binding domain 105 169 4.8E-7 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 Gene3D G3DSA:3.50.50.60 1 279 3.9E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS06230 1e49c55291cb9e0d467aa921d6603e92 338 Pfam PF00890 FAD binding domain 7 38 5.6E-5 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 Gene3D G3DSA:3.40.50.720 1 50 1.3E-14 T 28-03-2018 CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 Gene3D G3DSA:3.40.50.720 51 252 1.4E-55 T 28-03-2018 CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.1E-60 T 28-03-2018 CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 SUPERFAMILY SSF51735 8 246 8.05E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS15150 eac5496c257c41dd1ac44ace068d765f 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 9.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 9.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 SUPERFAMILY SSF46689 23 83 4.73E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 Gene3D G3DSA:1.10.10.60 13 61 1.6E-17 T 28-03-2018 CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 Gene3D G3DSA:1.10.260.40 62 170 9.9E-10 T 28-03-2018 CP478_RS16715 b9e58c3a25c02ca7288a89f16a3f377b 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 2.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 Gene3D G3DSA:3.40.50.740 133 311 2.1E-38 T 28-03-2018 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 Pfam PF01568 Molydopterin dinucleotide binding domain 660 718 3.6E-8 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 SUPERFAMILY SSF53706 69 649 9.68E-140 T 28-03-2018 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 Gene3D G3DSA:3.40.50.740 345 637 1.8E-45 T 28-03-2018 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 34 777 0.0 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 Gene3D G3DSA:2.40.40.20 654 779 1.7E-22 T 28-03-2018 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 SUPERFAMILY SSF50692 657 778 5.65E-16 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 PIRSF PIRSF000144 14 779 0.0 T 28-03-2018 CP478_RS15845 fede97063d55886db45f878c8c31fcb1 779 Pfam PF00384 Molybdopterin oxidoreductase 132 432 2.1E-26 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 Pfam PF00583 Acetyltransferase (GNAT) family 45 106 1.4E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 Pfam PF00583 Acetyltransferase (GNAT) family 194 299 1.1E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 SUPERFAMILY SSF55729 6 307 1.7E-44 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 Gene3D G3DSA:3.40.630.30 4 138 9.4E-12 T 28-03-2018 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 PIRSF PIRSF021524 2 314 1.6E-90 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 310 34.223 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 5 308 8.2E-129 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CP478_RS04445 cf2a5ae142b5c4fdd52ad95ed0baa2ea 315 Gene3D G3DSA:3.40.630.30 147 312 1.0E-18 T 28-03-2018 CP478_RS03980 e62bf23e323155ad24fc6ee3b0411b76 250 Pfam PF13490 Putative zinc-finger 33 58 3.4E-10 T 28-03-2018 IPR027383 Putative zinc-finger CP478_RS10695 03cbdb117d8dfa1a46899358a667c993 265 Pfam PF02405 Permease MlaE 49 257 8.1E-53 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 Pfam PF13638 PIN domain 7 145 1.6E-29 T 28-03-2018 IPR002716 PIN domain CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 SUPERFAMILY SSF52540 220 383 2.64E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 Gene3D G3DSA:3.40.50.1010 4 176 4.0E-30 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 Pfam PF02562 PhoH-like protein 222 426 4.4E-52 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 SUPERFAMILY SSF88723 97 140 7.19E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 SUPERFAMILY SSF88723 6 64 7.19E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 Gene3D G3DSA:3.40.50.300 219 424 3.4E-17 T 28-03-2018 CP478_RS06015 a01027237ca214e884ccfe0724d57e7c 433 SMART SM00670 5 132 4.9E-21 T 28-03-2018 IPR002716 PIN domain CP478_RS11220 c9e5a21acaf8ab9ebeaab570803fc1de 78 Gene3D G3DSA:2.30.170.40 2 75 3.8E-27 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11220 c9e5a21acaf8ab9ebeaab570803fc1de 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 21.453 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11220 c9e5a21acaf8ab9ebeaab570803fc1de 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.1E-23 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11220 c9e5a21acaf8ab9ebeaab570803fc1de 78 Pfam PF00830 Ribosomal L28 family 4 61 6.9E-24 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS11220 c9e5a21acaf8ab9ebeaab570803fc1de 78 SUPERFAMILY SSF143800 2 75 1.96E-26 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS14520 f2b2052f094db1af92ca7cd99ee356b5 154 Pfam PF02195 ParB-like nuclease domain 1 49 1.1E-5 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CP478_RS14520 f2b2052f094db1af92ca7cd99ee356b5 154 SUPERFAMILY SSF110849 3 85 1.34E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CP478_RS14520 f2b2052f094db1af92ca7cd99ee356b5 154 Gene3D G3DSA:3.90.1530.10 1 60 3.7E-8 T 28-03-2018 CP478_RS04475 ba66d67cacf9d70668b255bf343d4639 213 SUPERFAMILY SSF46689 14 87 3.8E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS04475 ba66d67cacf9d70668b255bf343d4639 213 Gene3D G3DSA:1.10.357.10 13 204 3.6E-26 T 28-03-2018 CP478_RS04475 ba66d67cacf9d70668b255bf343d4639 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 1.8E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00385 P450 superfamily signature 307 318 6.3E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00385 P450 superfamily signature 379 388 6.3E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00385 P450 superfamily signature 261 278 6.3E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00385 P450 superfamily signature 388 399 6.3E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 Gene3D G3DSA:1.10.630.10 2 451 1.9E-91 T 28-03-2018 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 381 390 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 36 55 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 346 370 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 250 267 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 378 388 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 388 411 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 PRINTS PR00463 E-class P450 group I signature 270 296 1.3E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 Pfam PF00067 Cytochrome P450 11 433 1.9E-61 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03040 a19ea216951cf81899714941b0544b4b 472 SUPERFAMILY SSF48264 9 439 1.1E-83 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS00055 4f7658dd300bf18895b5934bb3b01219 145 ProDom PD070500 MEMBRANE TRANSMEMBRANE MB0008C RV0008C/MT0010 1 104 1.0E-26 T 28-03-2018 IPR024245 Cell wall synthesis protein CwsA CP478_RS00055 4f7658dd300bf18895b5934bb3b01219 145 Pfam PF10814 Cell wall synthesis protein CwsA 9 145 8.7E-66 T 28-03-2018 IPR024245 Cell wall synthesis protein CwsA CP478_RS00055 4f7658dd300bf18895b5934bb3b01219 145 Hamap MF_00927 Cell wall synthesis protein CwsA [cwsA]. 4 145 25.601 T 28-03-2018 IPR024245 Cell wall synthesis protein CwsA CP478_RS10635 e1e8c981026c4b0689ead9bec423990c 170 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 72 158 1.8E-15 T 28-03-2018 IPR009241 Toxin HigB-like CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 PIRSF PIRSF005917 1 278 2.4E-88 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 Gene3D G3DSA:3.30.950.10 116 228 5.2E-39 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 85 96 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 9 273 8.5E-58 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 208 3.7E-24 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 SUPERFAMILY SSF53790 4 223 4.06E-67 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 Gene3D G3DSA:3.40.1010.10 3 115 8.8E-31 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS05490 764b25fc7f633bae0977664f1095b35e 285 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 5 225 32.68 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CP478_RS19415 012cd18a3d7207ec7b0008ff7ac9ec35 250 SUPERFAMILY SSF100950 3 246 2.76E-50 T 28-03-2018 CP478_RS19415 012cd18a3d7207ec7b0008ff7ac9ec35 250 SMART SM00882 6 209 0.0047 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS19415 012cd18a3d7207ec7b0008ff7ac9ec35 250 Gene3D G3DSA:3.40.1080.10 1 248 3.1E-29 T 28-03-2018 CP478_RS02060 2f0fd52b9bbe4e8521214a5b032bfd65 443 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 298 368 6.3E-8 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS02060 2f0fd52b9bbe4e8521214a5b032bfd65 443 SUPERFAMILY SSF140459 2 173 1.33E-63 T 28-03-2018 CP478_RS02060 2f0fd52b9bbe4e8521214a5b032bfd65 443 Gene3D G3DSA:1.10.287.1060 23 105 1.0E-6 T 28-03-2018 CP478_RS02060 2f0fd52b9bbe4e8521214a5b032bfd65 443 Pfam PF00823 PPE family 5 161 1.9E-62 T 28-03-2018 IPR000030 PPE family CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 Pfam PF00294 pfkB family carbohydrate kinase 15 288 2.9E-54 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 PRINTS PR00990 Ribokinase signature 45 64 6.1E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 PRINTS PR00990 Ribokinase signature 207 218 6.1E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 PRINTS PR00990 Ribokinase signature 18 39 6.1E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 PRINTS PR00990 Ribokinase signature 182 197 6.1E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 PRINTS PR00990 Ribokinase signature 116 129 6.1E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 SUPERFAMILY SSF53613 14 294 2.34E-58 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 Hamap MF_01987 Ribokinase [rbsK]. 14 295 22.005 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CP478_RS13310 fb6c2e1874af38dbe2d6b9085c146f43 304 Gene3D G3DSA:3.40.1190.20 13 304 2.9E-63 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS02700 a9b0559dc0619eab1bc5e16651948c6c 166 Hamap MF_00799 UPF0336 protein . 1 151 35.535 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS02700 a9b0559dc0619eab1bc5e16651948c6c 166 SUPERFAMILY SSF54637 10 147 3.66E-34 T 28-03-2018 IPR029069 HotDog domain CP478_RS02700 a9b0559dc0619eab1bc5e16651948c6c 166 Pfam PF13452 N-terminal half of MaoC dehydratase 10 140 1.8E-28 T 28-03-2018 CP478_RS02700 a9b0559dc0619eab1bc5e16651948c6c 166 Gene3D G3DSA:3.10.129.10 15 164 1.2E-28 T 28-03-2018 CP478_RS02700 a9b0559dc0619eab1bc5e16651948c6c 166 PIRSF PIRSF018072 1 153 1.8E-54 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS11135 e60c799bdaffbfa71b02fd1992af0356 439 Pfam PF01547 Bacterial extracellular solute-binding protein 54 350 3.5E-49 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CP478_RS11135 e60c799bdaffbfa71b02fd1992af0356 439 SUPERFAMILY SSF53850 38 426 7.09E-66 T 28-03-2018 CP478_RS11135 e60c799bdaffbfa71b02fd1992af0356 439 Gene3D G3DSA:3.40.190.10 151 436 8.8E-42 T 28-03-2018 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 SUPERFAMILY SSF100950 6 214 1.59E-74 T 28-03-2018 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 47 55 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 210 1.4E-99 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 SMART SM00882 9 205 2.7E-80 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 Pfam PF01144 Coenzyme A transferase 10 204 5.1E-49 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS13685 5f5e915e3328972ec50c7393f03fb886 218 Gene3D G3DSA:3.40.1080.10 6 215 1.9E-73 T 28-03-2018 CP478_RS01905 aa06188fc8dfc0061c63c3f489e68abf 214 Gene3D G3DSA:3.10.129.10 57 207 3.8E-21 T 28-03-2018 CP478_RS01905 aa06188fc8dfc0061c63c3f489e68abf 214 Pfam PF03061 Thioesterase superfamily 126 199 7.6E-10 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CP478_RS01905 aa06188fc8dfc0061c63c3f489e68abf 214 SUPERFAMILY SSF54637 15 207 4.25E-43 T 28-03-2018 IPR029069 HotDog domain CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 Gene3D G3DSA:1.20.1250.20 1 196 1.7E-31 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 SUPERFAMILY SSF103473 243 413 9.02E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 SUPERFAMILY SSF103473 3 195 9.02E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 SUPERFAMILY SSF103473 474 501 9.02E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 7 412 2.4E-85 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 Gene3D G3DSA:1.20.1250.20 247 513 4.3E-35 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 1.1E-8 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 1.1E-8 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.1E-8 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.1E-8 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 394 413 1.1E-8 T 28-03-2018 CP478_RS12725 dcc6bf495be85be26bab992cb1f2a965 537 Pfam PF07690 Major Facilitator Superfamily 14 403 6.2E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS10945 18517f1b62c16ab32418ec3ee8500caa 441 Gene3D G3DSA:1.10.10.10 220 307 2.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10945 18517f1b62c16ab32418ec3ee8500caa 441 Gene3D G3DSA:3.40.50.300 49 179 7.3E-5 T 28-03-2018 CP478_RS10945 18517f1b62c16ab32418ec3ee8500caa 441 Pfam PF13173 AAA domain 72 186 2.2E-15 T 28-03-2018 CP478_RS10945 18517f1b62c16ab32418ec3ee8500caa 441 Pfam PF13635 Domain of unknown function (DUF4143) 227 381 3.7E-23 T 28-03-2018 IPR025420 Domain of unknown function DUF4143 CP478_RS10945 18517f1b62c16ab32418ec3ee8500caa 441 SUPERFAMILY SSF52540 53 190 2.88E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS03350 9f513432a353d8c78538577038b7ddf3 84 Pfam PF07704 Rv0623-like transcription factor 1 83 2.1E-27 T 28-03-2018 IPR011660 Antitoxin VapB-like CP478_RS06250 4130ecffc0ea1bdce275cbf2fb4eef29 268 SUPERFAMILY SSF52096 15 267 2.93E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS06250 4130ecffc0ea1bdce275cbf2fb4eef29 268 Gene3D G3DSA:1.10.12.10 226 267 4.1E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS06250 4130ecffc0ea1bdce275cbf2fb4eef29 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 267 4.2E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS06250 4130ecffc0ea1bdce275cbf2fb4eef29 268 Gene3D G3DSA:3.90.226.10 15 225 2.3E-48 T 28-03-2018 CP478_RS12370 bae78238461413fc851af37eb4463ccc 289 Pfam PF16715 Cyclodipeptide synthase 64 283 1.0E-85 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CP478_RS12370 bae78238461413fc851af37eb4463ccc 289 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 64 283 5.0E-76 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CP478_RS12580 d7858da8717ca37f579d5ab8487148a7 151 Pfam PF00589 Phage integrase family 7 106 1.2E-15 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS12580 d7858da8717ca37f579d5ab8487148a7 151 Gene3D G3DSA:1.10.443.10 4 120 2.8E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CP478_RS12580 d7858da8717ca37f579d5ab8487148a7 151 SUPERFAMILY SSF56349 9 116 8.54E-24 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CP478_RS05690 e9258c8b7fa2ee12e802cc9110a36f1e 275 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 192 272 1.9E-18 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS05690 e9258c8b7fa2ee12e802cc9110a36f1e 275 SUPERFAMILY SSF140459 8 84 1.94E-21 T 28-03-2018 CP478_RS05690 e9258c8b7fa2ee12e802cc9110a36f1e 275 Pfam PF00934 PE family 1 91 1.8E-28 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS16285 abcd382ed1f7dc931aa8ad910ae551ec 459 Pfam PF01385 Probable transposase 205 320 7.4E-27 T 28-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CP478_RS16285 abcd382ed1f7dc931aa8ad910ae551ec 459 Pfam PF12323 Helix-turn-helix domain 13 48 4.2E-9 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CP478_RS16285 abcd382ed1f7dc931aa8ad910ae551ec 459 Pfam PF07282 Putative transposase DNA-binding domain 345 407 1.2E-13 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CP478_RS10485 7a1f72e0c5dfb894989d1ab2542df785 257 Pfam PF09844 Uncharacterized conserved protein (COG2071) 36 246 8.7E-61 T 28-03-2018 IPR018644 Protein of unknown function DUF2071 CP478_RS10485 7a1f72e0c5dfb894989d1ab2542df785 257 Gene3D G3DSA:2.40.400.10 17 250 3.8E-24 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 SUPERFAMILY SSF52540 5 235 2.6E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 Pfam PF00005 ABC transporter 25 168 1.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 SMART SM00382 34 245 3.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 Gene3D G3DSA:3.40.50.300 5 294 1.3E-58 T 28-03-2018 CP478_RS16040 d2950d451ab0dcef8ab725a96790b5c2 331 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 15 316 4.2E-125 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CP478_RS16575 43bf3de2abc1e3ffcb359c611522bace 274 SUPERFAMILY SSF53335 43 213 1.52E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16575 43bf3de2abc1e3ffcb359c611522bace 274 Gene3D G3DSA:3.40.50.150 36 113 3.0E-10 T 28-03-2018 CP478_RS16575 43bf3de2abc1e3ffcb359c611522bace 274 Pfam PF08241 Methyltransferase domain 66 157 3.3E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS16575 43bf3de2abc1e3ffcb359c611522bace 274 Gene3D G3DSA:3.40.50.150 114 229 6.5E-21 T 28-03-2018 CP478_RS16525 ac2a89c0066591e5c694f60fa6ffb83a 435 Gene3D G3DSA:1.10.287.1060 23 106 2.3E-5 T 28-03-2018 CP478_RS16525 ac2a89c0066591e5c694f60fa6ffb83a 435 Pfam PF00823 PPE family 8 164 7.6E-58 T 28-03-2018 IPR000030 PPE family CP478_RS16525 ac2a89c0066591e5c694f60fa6ffb83a 435 SUPERFAMILY SSF140459 5 177 4.71E-60 T 28-03-2018 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 282 318 1.7E-4 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 186 214 1.3E-9 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 Gene3D G3DSA:3.40.50.720 1 187 1.9E-35 T 28-03-2018 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 SUPERFAMILY SSF48179 184 334 1.16E-35 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 156 2.7E-39 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 60 89 8.7E-18 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 113 138 8.7E-18 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 8.7E-18 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 SMART SM01350 186 335 4.9E-5 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 Gene3D G3DSA:1.10.1040.10 188 340 1.1E-40 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 SUPERFAMILY SSF51735 1 160 5.53E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06145 af660a5e73896bcaa6ac38fdd7f0a96e 340 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 340 2.5E-162 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CP478_RS04895 3834b33e76f01ddead04056d6192c741 535 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 56 8.5E-9 T 28-03-2018 CP478_RS04895 3834b33e76f01ddead04056d6192c741 535 Gene3D G3DSA:3.50.50.60 2 534 2.8E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04895 3834b33e76f01ddead04056d6192c741 535 SUPERFAMILY SSF51905 1 324 2.5E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 Gene3D G3DSA:3.40.390.10 323 663 6.1E-110 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 Gene3D G3DSA:3.40.390.10 14 274 1.8E-12 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 Pfam PF01431 Peptidase family M13 452 659 1.2E-80 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 462 474 4.5E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 483 499 4.5E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 560 571 4.5E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 444 456 4.5E-23 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 SUPERFAMILY SSF55486 7 662 1.9E-205 T 28-03-2018 CP478_RS01080 1fc6db9ee03af0fdfb8a07415e2de0e1 663 Pfam PF05649 Peptidase family M13 20 400 4.0E-98 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 Gene3D G3DSA:3.90.940.10 36 110 7.6E-20 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 35 107 14.46 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 Pfam PF01192 RNA polymerase Rpb6 42 104 1.8E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 35 105 3.1E-28 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 SUPERFAMILY SSF63562 35 106 2.09E-22 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CP478_RS07620 9f57fbdc1a8258c2d447cf9c21a446da 110 SMART SM01409 42 106 2.2E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CP478_RS02505 8c512d7deb3430d7e3cca45179f06f5a 287 Pfam PF02353 Mycolic acid cyclopropane synthetase 5 283 1.5E-119 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02505 8c512d7deb3430d7e3cca45179f06f5a 287 PIRSF PIRSF003085 2 287 2.8E-116 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS02505 8c512d7deb3430d7e3cca45179f06f5a 287 Gene3D G3DSA:3.40.50.150 2 287 2.7E-57 T 28-03-2018 CP478_RS02505 8c512d7deb3430d7e3cca45179f06f5a 287 SUPERFAMILY SSF53335 13 287 4.06E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS09775 efa109ddaf609e16b65b657846cac254 503 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 23 103 2.6E-12 T 28-03-2018 IPR024962 YukD-like CP478_RS09775 efa109ddaf609e16b65b657846cac254 503 PIRSF PIRSF017804 14 503 2.0E-49 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS09775 efa109ddaf609e16b65b657846cac254 503 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 23 502 1.1E-135 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS02770 08b6ce6db76a34a36f52b13713c53e60 231 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 42 215 1.7E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS02770 08b6ce6db76a34a36f52b13713c53e60 231 Gene3D G3DSA:3.40.50.1110 38 229 2.1E-22 T 28-03-2018 CP478_RS02770 08b6ce6db76a34a36f52b13713c53e60 231 SUPERFAMILY SSF52266 40 225 3.66E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS20430 5018d016d6a0a2150abc2e7bd7f65cfc 224 Gene3D G3DSA:3.50.50.60 5 202 1.3E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20430 5018d016d6a0a2150abc2e7bd7f65cfc 224 SUPERFAMILY SSF51905 49 116 1.62E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Gene3D G3DSA:1.10.720.10 36 72 1.6E-10 T 28-03-2018 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SMART SM00382 345 530 8.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SUPERFAMILY SSF68912 36 76 3.41E-5 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Hamap MF_01884 Transcription termination factor Rho [rho]. 219 594 200.259 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 334 538 3.0E-25 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Pfam PF07498 Rho termination factor, N-terminal domain 37 71 1.3E-9 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SMART SM00959 36 78 1.8E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SUPERFAMILY SSF52540 296 545 2.51E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Gene3D G3DSA:2.40.50.140 225 281 5.2E-29 T 28-03-2018 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Gene3D G3DSA:3.40.50.300 282 542 1.3E-52 T 28-03-2018 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 Pfam PF07497 Rho termination factor, RNA-binding domain 226 303 1.3E-27 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SMART SM00357 227 288 9.9E-8 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 SUPERFAMILY SSF50249 227 302 1.08E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS07105 bdedba821e12620a84e51681c2d2d8e2 602 TIGRFAM TIGR00767 rho: transcription termination factor Rho 34 593 3.9E-218 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CP478_RS17125 3998bcc4dcec8be77a064709357f9a4a 193 SUPERFAMILY SSF53098 97 190 3.98E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS17125 3998bcc4dcec8be77a064709357f9a4a 193 Gene3D G3DSA:3.30.420.10 77 193 3.0E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 SUPERFAMILY SSF69864 172 396 1.96E-84 T 28-03-2018 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 SUPERFAMILY SSF52402 3 171 1.17E-39 T 28-03-2018 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 397 51.14 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 Gene3D G3DSA:3.90.1260.10 162 353 1.2E-75 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 Gene3D G3DSA:3.40.50.620 3 161 3.8E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 Pfam PF00764 Arginosuccinate synthase 6 392 2.0E-185 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 393 6.0E-141 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CP478_RS09070 86154c314ef77d1e93277a03bc5491d0 398 Gene3D G3DSA:1.20.5.470 363 396 1.2E-7 T 28-03-2018 CP478_RS09410 eac7b7d49414517bcb5b536b0471a1bc 236 SUPERFAMILY SSF46785 3 107 6.59E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09410 eac7b7d49414517bcb5b536b0471a1bc 236 Gene3D G3DSA:1.10.10.10 2 101 2.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09410 eac7b7d49414517bcb5b536b0471a1bc 236 Gene3D G3DSA:3.30.1050.10 102 213 8.4E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS09410 eac7b7d49414517bcb5b536b0471a1bc 236 Pfam PF01638 HxlR-like helix-turn-helix 16 101 8.2E-27 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CP478_RS09410 eac7b7d49414517bcb5b536b0471a1bc 236 SUPERFAMILY SSF55718 107 211 5.59E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CP478_RS11305 efef73b829751995ff5ca86043bed3f4 137 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 15 129 1.0E-29 T 28-03-2018 IPR019920 F420-binding domain, putative CP478_RS11305 efef73b829751995ff5ca86043bed3f4 137 SUPERFAMILY SSF50475 12 129 1.27E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS11305 efef73b829751995ff5ca86043bed3f4 137 Gene3D G3DSA:2.30.110.10 1 137 5.3E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS11305 efef73b829751995ff5ca86043bed3f4 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 93 2.0E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS18210 1c1041335d3a4a91c1ca349d243f6c54 184 Pfam PF01967 MoaC family 26 160 5.2E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS18210 1c1041335d3a4a91c1ca349d243f6c54 184 SUPERFAMILY SSF55040 22 165 1.31E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS18210 1c1041335d3a4a91c1ca349d243f6c54 184 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 15 162 1.5E-71 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS18210 1c1041335d3a4a91c1ca349d243f6c54 184 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 13 168 35.702 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS18210 1c1041335d3a4a91c1ca349d243f6c54 184 Gene3D G3DSA:3.30.70.640 14 168 3.4E-64 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 Hamap MF_00158 Pantothenate synthetase [panC]. 12 285 37.797 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 Gene3D G3DSA:3.40.50.620 1 185 5.6E-72 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 Gene3D G3DSA:3.30.1300.10 186 300 1.7E-36 T 28-03-2018 CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 Pfam PF02569 Pantoate-beta-alanine ligase 19 283 1.9E-91 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 22 286 9.7E-81 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CP478_RS19670 916ca0e3e759a7088ffee1a86905e799 309 SUPERFAMILY SSF52374 10 286 9.27E-101 T 28-03-2018 CP478_RS10285 6623ffb573f2b54f719b4d7d7bd50d80 118 SUPERFAMILY SSF53335 15 118 1.58E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10285 6623ffb573f2b54f719b4d7d7bd50d80 118 Gene3D G3DSA:3.40.50.150 1 118 1.7E-17 T 28-03-2018 CP478_RS10285 6623ffb573f2b54f719b4d7d7bd50d80 118 Pfam PF04072 Leucine carboxyl methyltransferase 19 118 3.5E-28 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS04725 36cc9211e11b096d92319d70938ccb97 141 Gene3D G3DSA:3.90.1170.40 3 141 3.4E-41 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS04725 36cc9211e11b096d92319d70938ccb97 141 SUPERFAMILY SSF54690 9 139 9.29E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS04725 36cc9211e11b096d92319d70938ccb97 141 Pfam PF02391 MoaE protein 9 121 1.5E-30 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 Pfam PF04542 Sigma-70 region 2 18 85 7.3E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 Gene3D G3DSA:1.10.10.10 88 177 3.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 40 72 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 SUPERFAMILY SSF88946 11 101 3.92E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 Pfam PF04545 Sigma-70, region 4 119 167 3.6E-14 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 SUPERFAMILY SSF88659 107 170 5.67E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 168 3.1E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03975 e537479971a29d86aa13e6c0f040685d 177 Gene3D G3DSA:1.10.1740.10 3 87 8.0E-21 T 28-03-2018 CP478_RS15820 1cb02a59ce7fdb9ed98618eb7616e692 283 Gene3D G3DSA:2.40.30.10 2 127 5.8E-27 T 28-03-2018 CP478_RS15820 1cb02a59ce7fdb9ed98618eb7616e692 283 Gene3D G3DSA:3.40.50.80 128 283 7.3E-42 T 28-03-2018 CP478_RS15820 1cb02a59ce7fdb9ed98618eb7616e692 283 SUPERFAMILY SSF63380 7 131 9.28E-9 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS15820 1cb02a59ce7fdb9ed98618eb7616e692 283 Pfam PF04954 Siderophore-interacting protein 134 262 3.3E-35 T 28-03-2018 IPR007037 Siderophore-interacting protein CP478_RS15820 1cb02a59ce7fdb9ed98618eb7616e692 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 127 1.3E-34 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CP478_RS19200 5282c34d0f7d63977682a1f7927f108c 218 Pfam PF13193 AMP-binding enzyme C-terminal domain 116 191 2.3E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS19200 5282c34d0f7d63977682a1f7927f108c 218 SUPERFAMILY SSF56801 56 202 3.79E-39 T 28-03-2018 CP478_RS19200 5282c34d0f7d63977682a1f7927f108c 218 Gene3D G3DSA:2.30.38.10 30 100 3.8E-5 T 28-03-2018 CP478_RS19200 5282c34d0f7d63977682a1f7927f108c 218 Gene3D G3DSA:3.30.300.30 104 211 4.8E-26 T 28-03-2018 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 Gene3D G3DSA:3.30.200.20 6 111 4.5E-21 T 28-03-2018 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 SMART SM00220 16 276 5.9E-52 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 Pfam PF14032 PknH-like extracellular domain 437 622 8.2E-54 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 SUPERFAMILY SSF56112 13 371 1.22E-73 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 Pfam PF00069 Protein kinase domain 16 261 9.5E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS06925 e62393ce9d0d3d75e3e2841a1db57064 626 Gene3D G3DSA:1.10.510.10 112 301 1.2E-43 T 28-03-2018 CP478_RS12000 c9bb24f2661fe45b253b61ecc69bea08 249 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 249 40.118 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS12000 c9bb24f2661fe45b253b61ecc69bea08 249 Pfam PF02654 Cobalamin-5-phosphate synthase 8 239 6.5E-44 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 Pfam PF09339 IclR helix-turn-helix domain 16 64 6.0E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 SMART SM00419 23 75 1.9E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 SMART SM00346 13 101 2.6E-32 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 SUPERFAMILY SSF55781 71 252 5.17E-39 T 28-03-2018 IPR029016 GAF domain-like CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 47 62 9.5E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 31 47 9.5E-5 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 Gene3D G3DSA:1.10.10.10 12 75 5.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 Pfam PF01614 Bacterial transcriptional regulator 127 253 3.0E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 SUPERFAMILY SSF46785 13 83 3.06E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09375 6439532e090c7886196bdb9de7d88cd4 259 Gene3D G3DSA:3.30.450.40 76 250 2.8E-39 T 28-03-2018 IPR029016 GAF domain-like CP478_RS10420 85ffe40e3fcc619cca264c77abf15c9f 367 ProSitePatterns PS00161 Isocitrate lyase signature. 213 218 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CP478_RS10420 85ffe40e3fcc619cca264c77abf15c9f 367 Pfam PF00463 Isocitrate lyase family 21 285 5.5E-70 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS10420 85ffe40e3fcc619cca264c77abf15c9f 367 Gene3D G3DSA:3.20.20.60 14 351 9.8E-93 T 28-03-2018 CP478_RS10420 85ffe40e3fcc619cca264c77abf15c9f 367 SUPERFAMILY SSF51621 11 316 2.38E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS16610 c732055b783cc85c7bc3274d07bdaee6 227 Gene3D G3DSA:3.90.640.20 137 226 1.5E-5 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CP478_RS16610 c732055b783cc85c7bc3274d07bdaee6 227 Pfam PF11738 Protein of unknown function (DUF3298) 145 220 1.3E-12 T 28-03-2018 IPR021729 Domain of unknown function DUF3298 CP478_RS16610 c732055b783cc85c7bc3274d07bdaee6 227 Gene3D G3DSA:3.30.565.40 48 136 5.7E-4 T 28-03-2018 CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 SUPERFAMILY SSF51735 9 247 4.67E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 Pfam PF00106 short chain dehydrogenase 9 195 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS11300 2f07589f178a9403f415c525945f01f9 249 Gene3D G3DSA:3.40.50.720 7 249 8.7E-36 T 28-03-2018 CP478_RS14160 fc36f3c40e3c32b48fa973855bf75dcf 223 Gene3D G3DSA:3.40.50.2020 51 221 4.4E-34 T 28-03-2018 CP478_RS14160 fc36f3c40e3c32b48fa973855bf75dcf 223 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 57 223 33.282 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CP478_RS14160 fc36f3c40e3c32b48fa973855bf75dcf 223 Pfam PF00156 Phosphoribosyl transferase domain 81 202 1.8E-16 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS14160 fc36f3c40e3c32b48fa973855bf75dcf 223 SUPERFAMILY SSF53271 61 217 6.69E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 SUPERFAMILY SSF51556 1 259 2.33E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 Gene3D G3DSA:3.20.20.140 1 264 1.7E-78 T 28-03-2018 CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 PIRSF PIRSF005902 1 261 5.6E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 258 1.8E-86 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 Pfam PF01026 TatD related DNase 2 257 6.2E-70 T 28-03-2018 IPR001130 TatD family GO:0016788 CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CP478_RS05515 8e01941acda974ff0b196bd5a446b9d4 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 194 210 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 8.0E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.9E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 Gene3D G3DSA:1.20.58.110 1 86 1.1E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.092 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 SUPERFAMILY SSF46992 3 86 1.44E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13170 307e084e42fe222dc486f89c205ea0c9 86 Pfam PF01649 Ribosomal protein S20 2 84 1.1E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13125 9b03fb68c82ef3c401abe05f98a43693 189 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 84 183 1.4E-8 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS13125 9b03fb68c82ef3c401abe05f98a43693 189 SUPERFAMILY SSF50118 82 183 3.27E-9 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS13125 9b03fb68c82ef3c401abe05f98a43693 189 Gene3D G3DSA:2.30.30.110 81 186 5.4E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS10455 1ad39bc3f8168ec39773c82b00b6f992 423 SUPERFAMILY SSF56784 67 116 8.39E-19 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10455 1ad39bc3f8168ec39773c82b00b6f992 423 SUPERFAMILY SSF56784 179 355 8.39E-19 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10455 1ad39bc3f8168ec39773c82b00b6f992 423 Gene3D G3DSA:3.40.50.1000 67 360 4.3E-16 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10455 1ad39bc3f8168ec39773c82b00b6f992 423 Pfam PF12710 haloacid dehalogenase-like hydrolase 217 339 1.9E-7 T 28-03-2018 CP478_RS00145 0bb7268e90bbe9fe8056a366027eaaed 120 Pfam PF10774 Domain of unknown function (DUF4226) 4 115 7.2E-40 T 28-03-2018 IPR019710 Protein of unknown function DUF4226 CP478_RS10795 e816e186777c4f6c696f9667a79e1ff8 558 Gene3D G3DSA:2.40.70.10 275 404 8.7E-5 T 28-03-2018 IPR021109 Aspartic peptidase domain CP478_RS10795 e816e186777c4f6c696f9667a79e1ff8 558 Pfam PF00934 PE family 2 93 3.2E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS10795 e816e186777c4f6c696f9667a79e1ff8 558 Gene3D G3DSA:1.10.287.1060 1 101 1.1E-4 T 28-03-2018 CP478_RS10795 e816e186777c4f6c696f9667a79e1ff8 558 SUPERFAMILY SSF140459 8 83 3.14E-25 T 28-03-2018 CP478_RS13000 bee631b48d206bf5c9c2ab7d15ba21d8 306 Pfam PF07859 alpha/beta hydrolase fold 77 277 1.5E-38 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS13000 bee631b48d206bf5c9c2ab7d15ba21d8 306 SUPERFAMILY SSF53474 12 298 6.46E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS13000 bee631b48d206bf5c9c2ab7d15ba21d8 306 Gene3D G3DSA:3.40.50.1820 29 305 1.4E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01835 b6d66d44ec979fb334adf8e8121bb08e 493 Pfam PF00350 Dynamin family 47 93 8.8E-8 T 28-03-2018 IPR022812 Dynamin superfamily CP478_RS01835 b6d66d44ec979fb334adf8e8121bb08e 493 Gene3D G3DSA:3.40.50.300 24 377 2.8E-21 T 28-03-2018 CP478_RS01835 b6d66d44ec979fb334adf8e8121bb08e 493 SUPERFAMILY SSF52540 42 253 4.28E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 SMART SM00729 88 325 3.0E-5 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Pfam PF04055 Radical SAM superfamily 552 724 1.9E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Pfam PF04055 Radical SAM superfamily 92 275 1.2E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 SUPERFAMILY SSF102114 509 819 1.15E-46 T 28-03-2018 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 SUPERFAMILY SSF102114 39 391 1.44E-37 T 28-03-2018 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Gene3D G3DSA:3.20.20.70 435 856 8.3E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Gene3D G3DSA:3.20.20.70 18 400 4.9E-33 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 510 852 4.6E-160 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 544 853 1.2E-113 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Hamap MF_01612 FO synthase subunit 2 [cofH]. 496 855 51.119 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 85 414 3.9E-144 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CP478_RS06440 656073ff2f0e8be60ec49507c05f4fb3 856 Hamap MF_01611 FO synthase subunit 1 [cofG]. 84 416 51.155 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CP478_RS07020 7f37bd3eb9464f538127ffedf1bfcefd 163 SMART SM00947 23 162 4.0E-26 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS07020 7f37bd3eb9464f538127ffedf1bfcefd 163 Pfam PF00484 Carbonic anhydrase 31 98 1.0E-11 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS07020 7f37bd3eb9464f538127ffedf1bfcefd 163 SUPERFAMILY SSF53056 4 161 4.32E-37 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS07020 7f37bd3eb9464f538127ffedf1bfcefd 163 Gene3D G3DSA:3.40.1050.10 2 163 8.0E-33 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19270 918e9bcbecd78e9439347f267a7dfa22 386 Gene3D G3DSA:2.102.10.10 23 127 5.9E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS19270 918e9bcbecd78e9439347f267a7dfa22 386 Pfam PF00355 Rieske [2Fe-2S] domain 26 109 7.9E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS19270 918e9bcbecd78e9439347f267a7dfa22 386 SUPERFAMILY SSF55961 124 342 1.28E-30 T 28-03-2018 CP478_RS19270 918e9bcbecd78e9439347f267a7dfa22 386 SUPERFAMILY SSF50022 19 131 2.49E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS19270 918e9bcbecd78e9439347f267a7dfa22 386 Gene3D G3DSA:3.90.380.10 128 345 1.2E-31 T 28-03-2018 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 SUPERFAMILY SSF88946 83 171 2.04E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 Pfam PF08281 Sigma-70, region 4 186 236 4.6E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 SUPERFAMILY SSF88659 163 242 3.36E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 Gene3D G3DSA:1.10.10.10 151 243 3.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 Gene3D G3DSA:1.10.1740.10 74 150 1.1E-23 T 28-03-2018 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 Pfam PF04542 Sigma-70 region 2 87 153 4.7E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS06685 e8d213922f852dac4714e22997c621b3 257 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 84 240 3.2E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CP478_RS03345 6c099f0c793a585fc6859cd4aff2fc7d 315 Pfam PF05305 Protein of unknown function (DUF732) 138 185 8.8E-6 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS10155 ec80d5324382476676e1b18f7a08d2f4 699 SUPERFAMILY SSF51735 3 246 1.11E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10155 ec80d5324382476676e1b18f7a08d2f4 699 Pfam PF13460 NAD(P)H-binding 8 105 1.4E-6 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10155 ec80d5324382476676e1b18f7a08d2f4 699 Gene3D G3DSA:3.40.50.720 2 207 2.0E-13 T 28-03-2018 CP478_RS16800 d4c01c1f4f4bc8ca6399a7abbdc6a86c 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 15 120 1.5E-24 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CP478_RS16800 d4c01c1f4f4bc8ca6399a7abbdc6a86c 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 12 125 18.973 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CP478_RS16800 d4c01c1f4f4bc8ca6399a7abbdc6a86c 126 TIGRFAM TIGR00494 crcB: protein CrcB 15 124 3.0E-26 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 SUPERFAMILY SSF53383 12 429 8.47E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 Pfam PF00202 Aminotransferase class-III 35 428 1.3E-112 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 9 433 48.882 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 21 430 9.7E-164 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 Gene3D G3DSA:3.90.1150.10 323 434 2.5E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS08585 ea17c7326654e1fded044b6a28e9701f 437 Gene3D G3DSA:3.40.640.10 73 322 7.5E-68 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 Pfam PF01196 Ribosomal protein L17 21 116 1.1E-35 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 7.2E-41 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 Gene3D G3DSA:3.90.1030.10 1 117 2.3E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.703 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS18915 ad2bea0235e26f5223756e99425bb0c4 180 SUPERFAMILY SSF64263 1 117 1.7E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS02720 5f6c2a2299b94c08ccbe1b86dce482fd 97 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 83 1.1E-16 T 28-03-2018 IPR008554 Glutaredoxin-like CP478_RS02720 5f6c2a2299b94c08ccbe1b86dce482fd 97 SUPERFAMILY SSF52833 2 84 1.08E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS02720 5f6c2a2299b94c08ccbe1b86dce482fd 97 Gene3D G3DSA:3.40.30.10 3 85 1.6E-12 T 28-03-2018 CP478_RS15995 6a355f1762b7dfb7885ac203a5a29ca5 245 Gene3D G3DSA:1.20.5.620 99 163 8.1E-10 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS15995 6a355f1762b7dfb7885ac203a5a29ca5 245 Gene3D G3DSA:1.20.5.620 164 206 1.8E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS15995 6a355f1762b7dfb7885ac203a5a29ca5 245 Gene3D G3DSA:1.20.5.620 60 98 5.2E-12 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CP478_RS17415 0c316d20537169da68e003b3654ff7cf 150 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 67 111 2.3E-9 T 28-03-2018 CP478_RS17415 0c316d20537169da68e003b3654ff7cf 150 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 67 132 7.4E-13 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS17415 0c316d20537169da68e003b3654ff7cf 150 Gene3D G3DSA:3.40.1620.10 66 115 2.7E-12 T 28-03-2018 CP478_RS17415 0c316d20537169da68e003b3654ff7cf 150 SUPERFAMILY SSF143120 67 110 1.15E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 Gene3D G3DSA:1.20.1250.20 261 496 3.6E-27 T 28-03-2018 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 Pfam PF00083 Sugar (and other) transporter 56 485 1.5E-90 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 50 481 7.7E-90 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 ProSitePatterns PS00216 Sugar transport proteins signature 1. 341 357 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 Gene3D G3DSA:1.20.1250.20 41 244 1.3E-30 T 28-03-2018 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 PRINTS PR00171 Sugar transporter signature 62 72 4.9E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 PRINTS PR00171 Sugar transporter signature 409 421 4.9E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 PRINTS PR00171 Sugar transporter signature 386 407 4.9E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 PRINTS PR00171 Sugar transporter signature 296 306 4.9E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 PRINTS PR00171 Sugar transporter signature 145 164 4.9E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 ProSitePatterns PS00217 Sugar transport proteins signature 2. 150 175 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS18245 971b2c51726ea6f53ad41feeaa97715d 502 SUPERFAMILY SSF103473 40 482 3.27E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS14865 e080d5e90b5d0269f32dc57a5f1e5d2a 352 Pfam PF13830 Domain of unknown function (DUF4192) 13 321 2.1E-84 T 28-03-2018 IPR025447 Protein of unknown function DUF4192 CP478_RS14865 e080d5e90b5d0269f32dc57a5f1e5d2a 352 Gene3D G3DSA:3.90.190.20 12 116 0.38 T 28-03-2018 CP478_RS14865 e080d5e90b5d0269f32dc57a5f1e5d2a 352 Gene3D G3DSA:3.90.190.20 120 265 0.027 T 28-03-2018 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.0E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.0E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.0E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.337 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 SUPERFAMILY SSF143034 2 62 3.53E-20 T 28-03-2018 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.4E-26 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CP478_RS08990 0d062d30264d831c4df8f3ee1d6256f6 64 Pfam PF01632 Ribosomal protein L35 2 62 7.2E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 192 3.0E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 Gene3D G3DSA:1.10.357.10 55 206 1.0E-16 T 28-03-2018 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 SUPERFAMILY SSF48498 86 200 9.54E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 Gene3D G3DSA:1.10.10.60 9 54 8.7E-14 T 28-03-2018 CP478_RS17335 9ae0abb1d33068024bbabab3f6d8e46f 208 SUPERFAMILY SSF46689 17 77 4.57E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 SMART SM00880 238 495 1.3E-66 T 28-03-2018 IPR007899 CHAD domain CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 SUPERFAMILY SSF55154 11 221 2.94E-42 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 Pfam PF01928 CYTH domain 12 138 4.2E-13 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 SMART SM01118 11 219 1.7E-16 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 Pfam PF05235 CHAD domain 239 462 7.0E-45 T 28-03-2018 IPR007899 CHAD domain CP478_RS12100 5c3ed998022a56dd76ad0ca15c4d2927 513 Gene3D G3DSA:2.40.320.10 9 226 3.1E-36 T 28-03-2018 CP478_RS04720 28d2b2693ab133f311e72895897b4d00 160 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 142 8.1E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS04720 28d2b2693ab133f311e72895897b4d00 160 Gene3D G3DSA:3.40.980.10 2 160 2.7E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS04720 28d2b2693ab133f311e72895897b4d00 160 SUPERFAMILY SSF53218 6 153 1.7E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS04720 28d2b2693ab133f311e72895897b4d00 160 Pfam PF00994 Probable molybdopterin binding domain 8 147 8.4E-25 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS04720 28d2b2693ab133f311e72895897b4d00 160 SMART SM00852 7 149 1.0E-16 T 28-03-2018 IPR001453 MoaB/Mog domain CP478_RS15795 e55d965afaad2d467b42970246129577 287 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 233 42.381 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15795 e55d965afaad2d467b42970246129577 287 Gene3D G3DSA:3.40.50.10490 5 259 1.1E-98 T 28-03-2018 CP478_RS15795 e55d965afaad2d467b42970246129577 287 SUPERFAMILY SSF52313 6 230 4.19E-94 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CP478_RS15795 e55d965afaad2d467b42970246129577 287 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.8E-110 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 196 210 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 87 104 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 6 24 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 37 46 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 158 175 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 PRINTS PR00395 Ribosomal protein S2 signature 175 186 4.8E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS15795 e55d965afaad2d467b42970246129577 287 Pfam PF00318 Ribosomal protein S2 9 224 1.5E-96 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS17915 286d0a6363398a647ffe611594f37de2 498 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 264 4.5E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS17915 286d0a6363398a647ffe611594f37de2 498 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 95 264 2.5E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS17915 286d0a6363398a647ffe611594f37de2 498 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 365 449 6.8E-13 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 SUPERFAMILY SSF51735 1 244 1.17E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 Gene3D G3DSA:3.40.50.720 1 248 3.6E-53 T 28-03-2018 CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 Pfam PF00106 short chain dehydrogenase 8 204 1.7E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00800 22683f169b8bd52d308c2b8594f2e351 286 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 198 6.1E-5 T 28-03-2018 CP478_RS12955 3749725fa13c426d8f6e5cd77b00c568 168 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 31 167 5.0E-64 T 28-03-2018 IPR020235 Low molecular weight antigen MTB12 CP478_RS00835 628664f87efa5112c5fc9cf832462690 276 Pfam PF13350 Tyrosine phosphatase family 5 275 2.0E-58 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CP478_RS00835 628664f87efa5112c5fc9cf832462690 276 SUPERFAMILY SSF52799 5 275 3.54E-60 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CP478_RS00835 628664f87efa5112c5fc9cf832462690 276 Gene3D G3DSA:3.90.190.10 14 212 1.4E-23 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CP478_RS11015 4121f83ad1364ec831a25806eaaf0e57 239 SUPERFAMILY SSF46689 181 234 6.63E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS11015 4121f83ad1364ec831a25806eaaf0e57 239 Gene3D G3DSA:1.10.10.10 183 239 6.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11015 4121f83ad1364ec831a25806eaaf0e57 239 PIRSF PIRSF037738 1 239 1.2E-102 T 28-03-2018 IPR017277 Putative antitoxin VapB45-like CP478_RS11015 4121f83ad1364ec831a25806eaaf0e57 239 Pfam PF04255 Protein of unknown function (DUF433) 183 234 3.6E-10 T 28-03-2018 IPR007367 Protein of unknown function DUF433 CP478_RS13345 b3ce3fc14e20f0b2578d022b1a80410e 103 SUPERFAMILY SSF141091 4 102 3.53E-31 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13345 b3ce3fc14e20f0b2578d022b1a80410e 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 6.9E-33 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13345 b3ce3fc14e20f0b2578d022b1a80410e 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 4.4E-24 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13345 b3ce3fc14e20f0b2578d022b1a80410e 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13345 b3ce3fc14e20f0b2578d022b1a80410e 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 103 19.699 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03185 6790ee37ed3bc01007db7f7827807549 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 129 14.238 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03185 6790ee37ed3bc01007db7f7827807549 130 Pfam PF01850 PIN domain 8 122 1.0E-14 T 28-03-2018 IPR002716 PIN domain CP478_RS03185 6790ee37ed3bc01007db7f7827807549 130 SUPERFAMILY SSF88723 5 130 2.21E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03185 6790ee37ed3bc01007db7f7827807549 130 Gene3D G3DSA:3.40.50.1010 3 130 1.0E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 Gene3D G3DSA:3.40.50.720 135 288 9.0E-33 T 28-03-2018 CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 SUPERFAMILY SSF50129 1 138 3.74E-31 T 28-03-2018 IPR011032 GroES-like CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 SUPERFAMILY SSF51735 115 279 3.34E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 85 3.5E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 SMART SM00829 7 319 4.7E-41 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 Pfam PF00107 Zinc-binding dehydrogenase 149 269 3.3E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS17205 4d69b1131c0e37bbb5f1039433438431 323 Gene3D G3DSA:3.90.180.10 1 134 3.5E-31 T 28-03-2018 CP478_RS20090 07a148e2e8afe4ea88e8ccb7d13ce1d1 340 Pfam PF02374 Anion-transporting ATPase 198 248 3.7E-5 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CP478_RS20090 07a148e2e8afe4ea88e8ccb7d13ce1d1 340 Pfam PF02374 Anion-transporting ATPase 23 181 5.4E-17 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CP478_RS20090 07a148e2e8afe4ea88e8ccb7d13ce1d1 340 SUPERFAMILY SSF52540 24 244 1.35E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20090 07a148e2e8afe4ea88e8ccb7d13ce1d1 340 Gene3D G3DSA:3.40.50.300 17 340 1.1E-41 T 28-03-2018 CP478_RS11210 a3110eda3f864367ac105aa4c8f24c02 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.603 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CP478_RS11210 a3110eda3f864367ac105aa4c8f24c02 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 3.5E-23 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11210 a3110eda3f864367ac105aa4c8f24c02 101 Gene3D G3DSA:4.10.830.10 1 101 4.3E-29 T 28-03-2018 CP478_RS11210 a3110eda3f864367ac105aa4c8f24c02 101 SUPERFAMILY SSF57716 2 101 9.03E-32 T 28-03-2018 CP478_RS20395 3289fe89c833cbec01b1536771c8ffd9 166 Gene3D G3DSA:3.90.79.10 1 163 1.5E-20 T 28-03-2018 CP478_RS20395 3289fe89c833cbec01b1536771c8ffd9 166 SUPERFAMILY SSF55811 2 150 3.11E-16 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS20395 3289fe89c833cbec01b1536771c8ffd9 166 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CP478_RS20395 3289fe89c833cbec01b1536771c8ffd9 166 Pfam PF00293 NUDIX domain 2 147 2.3E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS14250 769bac045ba52b20dc7fab499f15f9a3 523 Pfam PF01564 Spermine/spermidine synthase domain 301 460 1.9E-31 T 28-03-2018 CP478_RS14250 769bac045ba52b20dc7fab499f15f9a3 523 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 306 319 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CP478_RS14250 769bac045ba52b20dc7fab499f15f9a3 523 SUPERFAMILY SSF53335 231 498 2.92E-63 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14250 769bac045ba52b20dc7fab499f15f9a3 523 Gene3D G3DSA:3.40.50.150 285 505 1.3E-42 T 28-03-2018 CP478_RS14250 769bac045ba52b20dc7fab499f15f9a3 523 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 232 505 23.141 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CP478_RS15505 47bdb6b8642f9fa8928576e4a553837e 303 Gene3D G3DSA:1.10.3720.10 21 303 3.7E-52 T 28-03-2018 CP478_RS15505 47bdb6b8642f9fa8928576e4a553837e 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 302 1.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS15505 47bdb6b8642f9fa8928576e4a553837e 303 SUPERFAMILY SSF161098 64 290 1.57E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS13025 5b15f0702ee515a75bd4a281be365afa 154 Pfam PF06737 Transglycosylase-like domain 49 121 3.6E-32 T 28-03-2018 IPR010618 Transglycosylase-like CP478_RS13025 5b15f0702ee515a75bd4a281be365afa 154 SUPERFAMILY SSF53955 48 124 4.22E-28 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS13025 5b15f0702ee515a75bd4a281be365afa 154 Gene3D G3DSA:1.10.530.10 9 126 5.3E-28 T 28-03-2018 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 SUPERFAMILY SSF46785 12 102 5.31E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 SMART SM00418 25 103 4.9E-30 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 4.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 57 4.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 4.5E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 Pfam PF01022 Bacterial regulatory protein, arsR family 33 76 6.2E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS20445 bf7a7970a22526b74b9af9b961976f41 120 Gene3D G3DSA:1.10.10.10 2 120 2.3E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15785 638880ab95ac8a9da69bc2278d56cfb5 473 ProSitePatterns PS00571 Amidases signature. 155 186 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CP478_RS15785 638880ab95ac8a9da69bc2278d56cfb5 473 Gene3D G3DSA:3.90.1300.10 8 473 4.5E-103 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS15785 638880ab95ac8a9da69bc2278d56cfb5 473 Pfam PF01425 Amidase 33 451 8.7E-112 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS15785 638880ab95ac8a9da69bc2278d56cfb5 473 SUPERFAMILY SSF75304 9 460 2.62E-107 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS08130 58c9a142dec8799137072812cf1526d3 269 PIRSF PIRSF000094 2 269 2.8E-103 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CP478_RS08130 58c9a142dec8799137072812cf1526d3 269 SUPERFAMILY SSF51735 4 265 3.8E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08130 58c9a142dec8799137072812cf1526d3 269 Gene3D G3DSA:3.40.50.720 3 269 8.6E-34 T 28-03-2018 CP478_RS08130 58c9a142dec8799137072812cf1526d3 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 265 6.8E-56 T 28-03-2018 CP478_RS11405 263b69ed89e10f4564c001db0541ebd6 83 Pfam PF02416 mttA/Hcf106 family 4 54 2.6E-24 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CP478_RS11405 263b69ed89e10f4564c001db0541ebd6 83 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 3.1E-21 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CP478_RS11405 263b69ed89e10f4564c001db0541ebd6 83 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 80 21.402 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 Gene3D G3DSA:3.40.1390.30 254 357 3.4E-9 T 28-03-2018 CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 SUPERFAMILY SSF102705 4 369 6.15E-104 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 PIRSF PIRSF037489 1 371 8.8E-136 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 352 1.2E-59 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 Gene3D G3DSA:3.30.70.120 131 234 2.1E-39 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 354 5.3E-39 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CP478_RS12125 9b22a104b82d51a28a4049f851ff7f87 379 Gene3D G3DSA:3.40.1390.30 1 121 2.4E-28 T 28-03-2018 CP478_RS18355 0a09ad2946796ec294957a4dbad6fafd 264 Pfam PF08031 Berberine and berberine like 150 182 6.2E-7 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CP478_RS09955 b3a95aaa73e3242357bd95cf1c92d1d8 164 SUPERFAMILY SSF103256 2 136 1.01E-46 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CP478_RS09955 b3a95aaa73e3242357bd95cf1c92d1d8 164 Pfam PF02577 Bifunctional nuclease 6 127 5.2E-47 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CP478_RS21130 9fee1e65a25d8a538e6fdde0e905edc9 103 ProDom PD020336 ML0406 MB3895 RV3615C/MT3717 MB3645C 1 103 3.0E-37 T 28-03-2018 CP478_RS21130 9fee1e65a25d8a538e6fdde0e905edc9 103 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 100 6.4E-27 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CP478_RS19345 5f93f3ff29fe7025436bda713a6285ef 479 Pfam PF00823 PPE family 7 162 9.7E-57 T 28-03-2018 IPR000030 PPE family CP478_RS19345 5f93f3ff29fe7025436bda713a6285ef 479 Gene3D G3DSA:1.10.287.1060 19 108 6.1E-5 T 28-03-2018 CP478_RS19345 5f93f3ff29fe7025436bda713a6285ef 479 SUPERFAMILY SSF140459 3 171 6.02E-57 T 28-03-2018 CP478_RS19345 5f93f3ff29fe7025436bda713a6285ef 479 Gene3D G3DSA:3.40.50.1820 154 392 4.9E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19345 5f93f3ff29fe7025436bda713a6285ef 479 Pfam PF08237 PE-PPE domain 240 462 4.2E-65 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS09005 f24fb77bc195ebecc28e1ce54295a7b2 351 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 19 250 1.4E-52 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 9.0E-250 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 SUPERFAMILY SSF48592 370 522 5.19E-29 T 28-03-2018 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 2.7E-96 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.049 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 PRINTS PR00298 60kDa chaperonin signature 348 373 1.2E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 PRINTS PR00298 60kDa chaperonin signature 396 417 1.2E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 PRINTS PR00298 60kDa chaperonin signature 26 52 1.2E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 PRINTS PR00298 60kDa chaperonin signature 266 289 1.2E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 PRINTS PR00298 60kDa chaperonin signature 82 109 1.2E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 SUPERFAMILY SSF52029 184 374 1.64E-81 T 28-03-2018 IPR027409 GroEL-like apical domain CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 Gene3D G3DSA:3.50.7.10 201 370 2.3E-92 T 28-03-2018 IPR027409 GroEL-like apical domain CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 Gene3D G3DSA:1.10.560.10 371 513 5.8E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 SUPERFAMILY SSF48592 1 226 1.22E-63 T 28-03-2018 CP478_RS02340 0e9e6fd5e08baf2c8d2e9c6f825cb443 540 Gene3D G3DSA:1.10.560.10 1 200 5.3E-42 T 28-03-2018 IPR027413 GroEL-like equatorial domain CP478_RS18625 026c90b58a2e8e2fc2f21493a122e694 412 PIRSF PIRSF000390 33 412 2.5E-111 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CP478_RS18625 026c90b58a2e8e2fc2f21493a122e694 412 SUPERFAMILY SSF53383 37 407 6.27E-61 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS18625 026c90b58a2e8e2fc2f21493a122e694 412 Gene3D G3DSA:3.90.1150.10 272 409 2.9E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS18625 026c90b58a2e8e2fc2f21493a122e694 412 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 50 405 1.2E-94 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CP478_RS18625 026c90b58a2e8e2fc2f21493a122e694 412 Gene3D G3DSA:3.40.640.10 48 271 1.1E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 Gene3D G3DSA:3.40.710.10 239 624 3.0E-88 T 28-03-2018 CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 Gene3D G3DSA:1.10.3810.10 31 233 1.7E-65 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 Pfam PF00905 Penicillin binding protein transpeptidase domain 311 578 1.1E-26 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 SUPERFAMILY SSF53955 26 232 1.32E-63 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 Pfam PF00912 Transglycosylase 40 217 2.1E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 SUPERFAMILY SSF56601 199 221 7.51E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS00275 a68884372357deea6a993b3db272fbb9 678 SUPERFAMILY SSF56601 253 618 7.51E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS01430 244e6da6cdcb16019439fbfa61ac1048 330 Gene3D G3DSA:3.40.50.1980 164 327 3.3E-16 T 28-03-2018 CP478_RS01430 244e6da6cdcb16019439fbfa61ac1048 330 Gene3D G3DSA:3.40.50.1980 30 163 1.0E-30 T 28-03-2018 CP478_RS01430 244e6da6cdcb16019439fbfa61ac1048 330 Pfam PF01497 Periplasmic binding protein 60 297 4.0E-40 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CP478_RS01430 244e6da6cdcb16019439fbfa61ac1048 330 SUPERFAMILY SSF53807 39 320 2.2E-41 T 28-03-2018 CP478_RS09195 5e50fdf2aa65110eb018d4b2a149bb0e 74 Pfam PF03966 Trm112p-like protein 3 44 5.4E-8 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CP478_RS09195 5e50fdf2aa65110eb018d4b2a149bb0e 74 SUPERFAMILY SSF158997 1 59 4.84E-16 T 28-03-2018 CP478_RS09195 5e50fdf2aa65110eb018d4b2a149bb0e 74 Gene3D G3DSA:2.20.25.10 9 71 2.3E-21 T 28-03-2018 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Gene3D G3DSA:2.40.30.10 137 233 2.6E-19 T 28-03-2018 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Gene3D G3DSA:3.40.50.80 234 385 8.9E-16 T 28-03-2018 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Pfam PF00970 Oxidoreductase FAD-binding domain 151 242 2.5E-19 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Pfam PF00042 Globin 11 100 1.2E-8 T 28-03-2018 IPR000971 Globin GO:0020037 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 175 187 6.4E-15 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 252 271 6.4E-15 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 277 286 6.4E-15 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 6.4E-15 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 SUPERFAMILY SSF63380 147 242 3.94E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Gene3D G3DSA:1.10.490.10 2 136 4.7E-25 T 28-03-2018 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 175 185 4.2E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 277 286 4.2E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 252 271 4.2E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 SUPERFAMILY SSF52343 245 386 1.44E-23 T 28-03-2018 CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 SUPERFAMILY SSF46458 5 139 1.55E-20 T 28-03-2018 IPR009050 Globin-like CP478_RS02050 b23bb9d2a2de655b45fd30ccd2feafe7 390 Pfam PF00175 Oxidoreductase NAD-binding domain 253 370 5.1E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CP478_RS10255 dcfd28e3f902484f6c9defb9c37ff4d5 325 Gene3D G3DSA:3.40.50.1820 39 324 5.9E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10255 dcfd28e3f902484f6c9defb9c37ff4d5 325 SUPERFAMILY SSF53474 41 323 5.93E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10255 dcfd28e3f902484f6c9defb9c37ff4d5 325 Pfam PF00756 Putative esterase 55 318 6.4E-76 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS15850 a7b37e6a472321afbf6358ff1955dee5 101 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 4.6E-52 T 28-03-2018 IPR019592 Protein of unknown function DUF2469 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 24 301 41.265 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 Pfam PF13649 Methyltransferase domain 134 209 3.0E-9 T 28-03-2018 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 Gene3D G3DSA:3.40.50.150 96 304 6.6E-37 T 28-03-2018 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 206 212 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 Gene3D G3DSA:1.10.8.10 15 95 2.5E-14 T 28-03-2018 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 SUPERFAMILY SSF53335 24 298 8.14E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 46 297 1.8E-59 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CP478_RS07125 ed272300767029ce08b9750db1cee1ca 325 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 75 300 1.9E-43 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CP478_RS00675 6d93c8d3df3504116923c5bb3be78ee0 122 Gene3D G3DSA:1.10.1220.10 63 117 2.2E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS14380 0a3b62c83719f6c07705f43b71ece84b 393 SUPERFAMILY SSF54631 246 367 6.34E-15 T 28-03-2018 CP478_RS14380 0a3b62c83719f6c07705f43b71ece84b 393 Gene3D G3DSA:3.10.580.10 228 368 3.6E-17 T 28-03-2018 CP478_RS14380 0a3b62c83719f6c07705f43b71ece84b 393 Pfam PF00571 CBS domain 311 367 5.0E-7 T 28-03-2018 IPR000644 CBS domain CP478_RS14380 0a3b62c83719f6c07705f43b71ece84b 393 Pfam PF02163 Peptidase family M50 136 197 7.7E-9 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CP478_RS14380 0a3b62c83719f6c07705f43b71ece84b 393 PIRSF PIRSF006404 1 377 3.3E-115 T 28-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CP478_RS11105 6604b8ace1f86abdd277f5039d8da28b 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 151 7.7E-8 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CP478_RS11105 6604b8ace1f86abdd277f5039d8da28b 162 SUPERFAMILY SSF55961 6 156 3.81E-37 T 28-03-2018 CP478_RS11105 6604b8ace1f86abdd277f5039d8da28b 162 Gene3D G3DSA:3.30.530.20 1 156 1.6E-17 T 28-03-2018 IPR023393 START-like domain CP478_RS11145 81583a769edefd3696976493195c3aa4 186 SUPERFAMILY SSF52499 2 183 6.02E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CP478_RS11145 81583a769edefd3696976493195c3aa4 186 Gene3D G3DSA:3.40.50.850 1 186 1.2E-56 T 28-03-2018 CP478_RS11145 81583a769edefd3696976493195c3aa4 186 Pfam PF00857 Isochorismatase family 3 182 2.2E-32 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 PIRSF PIRSF500176 11 326 4.8E-83 T 28-03-2018 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 PRINTS PR00139 Asparaginase/glutaminase family signature 87 105 1.7E-11 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 PRINTS PR00139 Asparaginase/glutaminase family signature 15 26 1.7E-11 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 Gene3D G3DSA:3.40.50.40 208 325 4.0E-21 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 Pfam PF00710 Asparaginase, N-terminal 15 180 6.2E-44 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 Gene3D G3DSA:3.40.50.1170 12 193 9.6E-44 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 88 98 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 PIRSF PIRSF001220 11 325 7.6E-79 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 SMART SM00870 14 322 5.0E-95 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 17 25 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CP478_RS08430 2ebc78af710e482564a93a8055868780 326 SUPERFAMILY SSF53774 12 325 1.96E-75 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CP478_RS11335 ec7dbb5be3f252f852d662525b928afd 656 Gene3D G3DSA:3.40.50.1820 349 595 6.9E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11335 ec7dbb5be3f252f852d662525b928afd 656 Pfam PF06259 Alpha/beta hydrolase 348 520 6.2E-31 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CP478_RS00115 4539f5144390cac4d0de12a8328b10af 527 Pfam PF00498 FHA domain 456 518 1.9E-16 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS00115 4539f5144390cac4d0de12a8328b10af 527 Pfam PF12401 Protein of unknown function (DUF2662) 9 121 7.5E-35 T 28-03-2018 IPR022128 Domain of unknown function DUF3662 CP478_RS00115 4539f5144390cac4d0de12a8328b10af 527 Gene3D G3DSA:2.60.200.20 420 527 2.0E-24 T 28-03-2018 CP478_RS00115 4539f5144390cac4d0de12a8328b10af 527 SUPERFAMILY SSF49879 398 525 8.42E-29 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS00115 4539f5144390cac4d0de12a8328b10af 527 SMART SM00240 454 504 9.6E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 Gene3D G3DSA:3.40.50.620 2 196 8.0E-72 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 Gene3D G3DSA:1.10.240.10 197 317 9.2E-30 T 28-03-2018 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 Pfam PF00579 tRNA synthetases class I (W and Y) 7 289 3.8E-81 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 334 1.7E-99 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 SUPERFAMILY SSF52374 9 334 7.88E-92 T 28-03-2018 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 9.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 9.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 9.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 9.3E-28 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CP478_RS18275 151ad8a3adc491e27de5a154d7bb6420 336 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 335 41.012 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Gene3D G3DSA:1.20.140.10 226 387 7.8E-27 T 28-03-2018 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 378 2.5E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 SUPERFAMILY SSF56645 4 241 4.71E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 209 4.0E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.9E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Gene3D G3DSA:1.10.540.10 1 120 7.0E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 SUPERFAMILY SSF47203 228 378 7.57E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19365 22a229f0c58632b928291783b8523b81 387 Gene3D G3DSA:2.40.110.10 122 225 5.1E-33 T 28-03-2018 CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 SUPERFAMILY SSF140459 8 84 1.2E-22 T 28-03-2018 CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 Pfam PF00934 PE family 2 92 9.9E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 PRINTS PR01228 Eggshell protein signature 243 258 6.0E-6 T 28-03-2018 CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 PRINTS PR01228 Eggshell protein signature 272 282 6.0E-6 T 28-03-2018 CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 PRINTS PR01228 Eggshell protein signature 182 193 6.0E-6 T 28-03-2018 CP478_RS05855 2a3e761bdb037d3353161049ec4b41a1 667 PRINTS PR01228 Eggshell protein signature 298 316 6.0E-6 T 28-03-2018 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 Gene3D G3DSA:1.10.10.10 4 103 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 Pfam PF01022 Bacterial regulatory protein, arsR family 27 72 8.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 SUPERFAMILY SSF46785 13 92 5.86E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 SMART SM00418 20 98 6.6E-32 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 1.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 52 1.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS04485 899195fce8109f68a6c007cc0120819a 130 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 SMART SM00937 83 196 9.9E-46 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 SUPERFAMILY SSF75620 28 367 2.35E-118 T 28-03-2018 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 Gene3D G3DSA:1.20.58.410 3 117 1.1E-27 T 28-03-2018 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 366 1.7E-165 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 246 262 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 366 38.277 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 Pfam PF03462 PCRF domain 29 221 4.5E-56 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 Pfam PF00472 RF-1 domain 231 338 9.2E-36 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CP478_RS16995 97254374f46a80d9ac6f29888a704804 371 Gene3D G3DSA:3.30.160.20 226 315 2.0E-30 T 28-03-2018 CP478_RS10245 a0b6f1b09027bbf928cdba09ac43808f 176 SUPERFAMILY SSF53955 70 146 2.28E-30 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS10245 a0b6f1b09027bbf928cdba09ac43808f 176 Gene3D G3DSA:1.10.530.10 35 147 1.4E-30 T 28-03-2018 CP478_RS10245 a0b6f1b09027bbf928cdba09ac43808f 176 Pfam PF06737 Transglycosylase-like domain 70 140 2.7E-33 T 28-03-2018 IPR010618 Transglycosylase-like CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 ProSitePatterns PS00480 Citrate synthase signature. 278 290 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 Gene3D G3DSA:1.10.580.10 286 375 1.5E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 30 387 4.0E-139 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 SUPERFAMILY SSF48256 28 388 6.67E-118 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PIRSF PIRSF001369 24 391 3.7E-117 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 Pfam PF00285 Citrate synthase, C-terminal domain 31 377 2.6E-114 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 Gene3D G3DSA:1.10.580.10 36 284 2.7E-88 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 271 291 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 147 160 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 196 211 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 218 246 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 328 344 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS06190 7007956f829b49fdb7f90693ef43098e 393 PRINTS PR00143 Citrate synthase signature 348 362 3.5E-35 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Gene3D G3DSA:2.40.30.10 309 416 4.8E-26 T 28-03-2018 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 SUPERFAMILY SSF50465 311 415 2.69E-30 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 PRINTS PR00315 GTP-binding elongation factor signature 6 19 6.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 PRINTS PR00315 GTP-binding elongation factor signature 138 147 6.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 414 3.3E-173 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 1 443 48.789 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Gene3D G3DSA:3.40.50.300 438 614 2.0E-40 T 28-03-2018 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 SUPERFAMILY SSF50447 220 308 1.43E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 SUPERFAMILY SSF52540 440 612 3.9E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Pfam PF00009 Elongation factor Tu GTP binding domain 5 188 3.1E-39 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Pfam PF01583 Adenylylsulphate kinase 442 595 1.5E-67 T 28-03-2018 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 441 614 37.133 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Gene3D G3DSA:3.40.50.300 2 212 1.1E-37 T 28-03-2018 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 Gene3D G3DSA:2.40.30.10 215 307 4.5E-19 T 28-03-2018 CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 SUPERFAMILY SSF52540 4 204 3.25E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07030 74372879da8711fd92c9331a7528c50e 614 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 441 609 6.1E-63 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CP478_RS06630 eb21a59ab87a4b0a49af03ceffa6f336 204 Pfam PF03352 Methyladenine glycosylase 20 187 3.4E-66 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CP478_RS06630 eb21a59ab87a4b0a49af03ceffa6f336 204 SUPERFAMILY SSF48150 7 189 4.03E-65 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS06630 eb21a59ab87a4b0a49af03ceffa6f336 204 Gene3D G3DSA:1.10.340.30 6 189 6.7E-73 T 28-03-2018 CP478_RS06630 eb21a59ab87a4b0a49af03ceffa6f336 204 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 7 189 7.5E-94 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 Pfam PF00203 Ribosomal protein S19 3 83 1.1E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 PIRSF PIRSF002144 1 93 3.8E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 Gene3D G3DSA:3.30.860.10 1 92 1.1E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 SUPERFAMILY SSF54570 3 83 5.49E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 4.9E-48 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.374 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03825 0ef07da0ce47d18061f642c5f54f9cfa 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS05410 fe4b39d768fe0031ac86c21902eba7e6 110 Pfam PF09723 Zinc ribbon domain 2 40 2.9E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CP478_RS05410 fe4b39d768fe0031ac86c21902eba7e6 110 SMART SM00834 2 41 3.1E-10 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CP478_RS05410 fe4b39d768fe0031ac86c21902eba7e6 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 6.4E-17 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CP478_RS09800 63d7881c42f0e0a4c42643e37a41ae52 655 SUPERFAMILY SSF140459 4 170 2.54E-55 T 28-03-2018 CP478_RS09800 63d7881c42f0e0a4c42643e37a41ae52 655 SUPERFAMILY SSF53474 217 400 1.18E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09800 63d7881c42f0e0a4c42643e37a41ae52 655 Pfam PF00823 PPE family 7 163 3.2E-56 T 28-03-2018 IPR000030 PPE family CP478_RS09800 63d7881c42f0e0a4c42643e37a41ae52 655 Gene3D G3DSA:3.40.50.1820 206 421 3.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09800 63d7881c42f0e0a4c42643e37a41ae52 655 Pfam PF08237 PE-PPE domain 245 469 9.9E-78 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS01955 af31c3004dbd318115bf30eaf5213d5c 197 Gene3D G3DSA:3.40.50.300 6 171 3.7E-15 T 28-03-2018 CP478_RS01955 af31c3004dbd318115bf30eaf5213d5c 197 SUPERFAMILY SSF52540 6 139 3.14E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01955 af31c3004dbd318115bf30eaf5213d5c 197 Pfam PF06414 Zeta toxin 4 155 2.3E-13 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CP478_RS16630 9645ae39e85aaafa989e67f1648d0ab0 288 SUPERFAMILY SSF55811 11 67 5.99E-15 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS16630 9645ae39e85aaafa989e67f1648d0ab0 288 SUPERFAMILY SSF55811 99 110 5.99E-15 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS16630 9645ae39e85aaafa989e67f1648d0ab0 288 SUPERFAMILY SSF55811 159 226 5.99E-15 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS16630 9645ae39e85aaafa989e67f1648d0ab0 288 Gene3D G3DSA:3.90.79.10 8 245 1.1E-28 T 28-03-2018 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 Gene3D G3DSA:3.30.70.1230 338 531 2.4E-38 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 SMART SM00044 325 515 5.2E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 Pfam PF00672 HAMP domain 280 326 3.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 SUPERFAMILY SSF158472 279 326 1.07E-6 T 28-03-2018 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 358 526 1.3E-19 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 SMART SM00304 277 329 5.9E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS07240 11a48a0931486b1a988910b3c8420259 567 SUPERFAMILY SSF55073 352 531 8.63E-44 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 Pfam PF00574 Clp protease 18 192 3.8E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 2.0E-47 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.0E-47 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.0E-47 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.0E-47 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 2.0E-47 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 38.391 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 SUPERFAMILY SSF52096 19 192 5.76E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS13445 fad1b77a87b0e4bee7decb6e11061a93 200 Gene3D G3DSA:3.90.226.10 21 193 4.3E-41 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Pfam PF00689 Cation transporting ATPase, C-terminus 726 892 5.7E-39 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Gene3D G3DSA:3.40.1110.10 295 542 6.3E-41 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF81660 338 539 5.89E-45 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Pfam PF00122 E1-E2 ATPase 119 311 5.1E-54 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF81653 122 231 1.44E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 213 351 1.2E-24 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 186 3.8E-19 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 613 732 5.6E-35 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SMART SM00831 10 84 2.0E-28 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Pfam PF00702 haloacid dehalogenase-like hydrolase 329 655 2.1E-18 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 567 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 660 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 331 345 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 677 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 546 3.6E-39 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Gene3D G3DSA:1.20.1110.10 556 902 8.4E-83 T 28-03-2018 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF81665 232 325 3.01E-119 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF81665 11 122 3.01E-119 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF81665 691 899 3.01E-119 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Pfam PF00690 Cation transporter/ATPase, N-terminus 12 78 8.8E-18 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 333 339 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 673 698 1.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 629 1.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 657 1.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 493 511 1.5E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF56784 329 349 4.61E-56 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 SUPERFAMILY SSF56784 490 745 4.61E-56 T 28-03-2018 IPR023214 HAD-like domain CP478_RS10890 fe117bcee3659a76e00474c104887f40 905 Gene3D G3DSA:2.70.150.10 19 232 1.8E-48 T 28-03-2018 CP478_RS03565 be2811b2fa12befcc4fe209b3495ee62 145 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 132 13.124 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03565 be2811b2fa12befcc4fe209b3495ee62 145 SUPERFAMILY SSF88723 1 127 3.92E-12 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03565 be2811b2fa12befcc4fe209b3495ee62 145 Pfam PF01850 PIN domain 2 126 4.6E-12 T 28-03-2018 IPR002716 PIN domain CP478_RS03565 be2811b2fa12befcc4fe209b3495ee62 145 Gene3D G3DSA:3.40.50.1010 1 135 6.8E-12 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 SUPERFAMILY SSF46894 142 211 1.33E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 Gene3D G3DSA:1.10.10.10 110 211 2.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 SMART SM00421 148 205 1.7E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 3.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS01065 f2a208190e30cc2750df718d504b3541 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CP478_RS15300 955dad6488a896d2d40f87a64d649897 324 Pfam PF00149 Calcineurin-like phosphoesterase 16 250 2.7E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CP478_RS15300 955dad6488a896d2d40f87a64d649897 324 Gene3D G3DSA:3.60.21.10 15 289 3.0E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS15300 955dad6488a896d2d40f87a64d649897 324 SUPERFAMILY SSF56300 14 268 8.33E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS10790 2772e36906939651aa9d7951ea1afc29 86 Pfam PF07704 Rv0623-like transcription factor 2 81 2.9E-19 T 28-03-2018 IPR011660 Antitoxin VapB-like CP478_RS21275 dbe1a1e2f7345d50a116519fb456b81c 77 Pfam PF00934 PE family 4 75 2.2E-8 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 Pfam PF00561 alpha/beta hydrolase fold 27 131 2.0E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 293 315 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 113 126 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 53 68 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 99 112 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 33 51 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 PRINTS PR00412 Epoxide hydrolase signature 259 275 9.4E-33 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 Gene3D G3DSA:3.40.50.1820 5 321 2.9E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19755 6ef385359e5a8eae321d97f407e98884 322 SUPERFAMILY SSF53474 4 318 5.51E-74 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20285 8ed30da67cbf8e3b9ed795b032e6722b 231 SUPERFAMILY SSF52317 14 209 8.54E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS20285 8ed30da67cbf8e3b9ed795b032e6722b 231 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 3 197 1.3E-35 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CP478_RS20285 8ed30da67cbf8e3b9ed795b032e6722b 231 Gene3D G3DSA:3.40.50.880 1 210 1.9E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 Gene3D G3DSA:3.90.1150.10 245 350 1.6E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 Gene3D G3DSA:3.40.640.10 37 244 3.4E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 350 47.482 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 351 45.295 T 28-03-2018 IPR024892 Putative phenylalanine aminotransferase CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 SUPERFAMILY SSF53383 19 348 2.64E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS20610 6ea07f238a9a4cfcb49fd6eb95827f6b 353 Pfam PF00155 Aminotransferase class I and II 25 338 1.4E-47 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 58 133 23.88 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 PRINTS PR00973 Ribosomal protein S17 family signature 77 100 3.3E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 PRINTS PR00973 Ribosomal protein S17 family signature 109 119 3.3E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 PRINTS PR00973 Ribosomal protein S17 family signature 119 126 3.3E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 58 129 1.9E-32 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 SUPERFAMILY SSF50249 57 135 1.29E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS03850 7dc099415233651937d05f1b59240b03 136 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 62 129 7.0E-33 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 Gene3D G3DSA:2.40.50.140 58 135 6.5E-28 T 28-03-2018 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 ProSitePatterns PS00056 Ribosomal protein S17 signature. 109 121 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03850 7dc099415233651937d05f1b59240b03 136 Pfam PF00366 Ribosomal protein S17 63 130 8.9E-29 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS19080 1dd5ae4ac6189afee2bc9a71d690d19a 107 Pfam PF03551 Transcriptional regulator PadR-like family 13 83 4.5E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CP478_RS19080 1dd5ae4ac6189afee2bc9a71d690d19a 107 SUPERFAMILY SSF46785 3 95 6.34E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS19080 1dd5ae4ac6189afee2bc9a71d690d19a 107 Gene3D G3DSA:1.10.10.10 1 100 4.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.2E-20 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 SUPERFAMILY SSF46561 8 67 3.01E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 Pfam PF00831 Ribosomal L29 protein 9 64 2.1E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 16.873 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03845 a1bb12b05833f53435726035b3557d6f 77 Gene3D G3DSA:1.10.287.310 6 68 5.5E-23 T 28-03-2018 CP478_RS02565 aa47aebb90d2b1b5c04744d8446c2a74 174 Gene3D G3DSA:3.30.530.20 1 166 1.0E-7 T 28-03-2018 IPR023393 START-like domain CP478_RS02565 aa47aebb90d2b1b5c04744d8446c2a74 174 Pfam PF10698 Protein of unknown function (DUF2505) 6 170 2.7E-45 T 28-03-2018 IPR019639 Protein of unknown function DUF2505 CP478_RS08575 c53a03c90e80e8b0f49eab4d844c7b37 230 SUPERFAMILY SSF54001 36 165 1.37E-23 T 28-03-2018 CP478_RS08575 c53a03c90e80e8b0f49eab4d844c7b37 230 Pfam PF00877 NlpC/P60 family 55 167 2.5E-26 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CP478_RS08575 c53a03c90e80e8b0f49eab4d844c7b37 230 Gene3D G3DSA:3.90.1720.10 36 182 5.1E-29 T 28-03-2018 CP478_RS18870 b9803e9b835da7cfc445242da1e6bb44 467 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 461 1.1E-124 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS18870 b9803e9b835da7cfc445242da1e6bb44 467 PIRSF PIRSF017804 1 464 3.5E-56 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS18870 b9803e9b835da7cfc445242da1e6bb44 467 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 83 4.3E-20 T 28-03-2018 IPR024962 YukD-like CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Gene3D G3DSA:1.20.950.20 424 631 4.8E-46 T 28-03-2018 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Pfam PF02613 Nitrate reductase delta subunit 292 406 4.3E-8 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 416 639 3.0E-57 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Gene3D G3DSA:3.40.50.740 109 288 1.0E-33 T 28-03-2018 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Pfam PF02665 Nitrate reductase gamma subunit 419 639 6.8E-85 T 28-03-2018 IPR023234 NarG-like domain CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Gene3D G3DSA:2.20.25.90 65 108 4.0E-26 T 28-03-2018 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 SUPERFAMILY SSF53706 15 255 1.57E-84 T 28-03-2018 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 263 409 1.5E-41 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 58 77 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 SMART SM00926 53 115 5.6E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 SUPERFAMILY SSF103501 415 639 1.03E-67 T 28-03-2018 IPR023234 NarG-like domain CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Gene3D G3DSA:1.10.3480.10 289 423 2.2E-18 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 Pfam PF00384 Molybdopterin oxidoreductase 118 252 1.7E-31 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS09475 8df3098e19a3bc5590313cb989e72611 652 SUPERFAMILY SSF89155 258 412 4.19E-23 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CP478_RS01275 b64bbd5f0ec67e27e8dc7fe20a91e296 1400 Gene3D G3DSA:2.60.120.260 937 1120 3.6E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS01275 b64bbd5f0ec67e27e8dc7fe20a91e296 1400 SUPERFAMILY SSF49785 939 1081 2.06E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS01275 b64bbd5f0ec67e27e8dc7fe20a91e296 1400 Gene3D G3DSA:2.60.120.260 707 845 1.6E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS01275 b64bbd5f0ec67e27e8dc7fe20a91e296 1400 Pfam PF11847 Domain of unknown function (DUF3367) 16 692 3.5E-281 T 28-03-2018 IPR021798 Protein of unknown function DUF3367 MetaCyc: PWY-6397 CP478_RS01275 b64bbd5f0ec67e27e8dc7fe20a91e296 1400 SUPERFAMILY SSF49785 709 826 1.98E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CP478_RS02205 c63e286a42f00979cc4ad25a3f6e4d47 222 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 214 6.2E-61 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CP478_RS02205 c63e286a42f00979cc4ad25a3f6e4d47 222 SUPERFAMILY SSF51391 7 218 2.09E-59 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CP478_RS02205 c63e286a42f00979cc4ad25a3f6e4d47 222 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 9 219 24.447 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CP478_RS02205 c63e286a42f00979cc4ad25a3f6e4d47 222 Pfam PF02581 Thiamine monophosphate synthase 11 201 8.1E-53 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CP478_RS02205 c63e286a42f00979cc4ad25a3f6e4d47 222 Gene3D G3DSA:3.20.20.70 1 219 4.8E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 Gene3D G3DSA:3.40.50.1820 1 300 2.1E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 SUPERFAMILY SSF53474 17 296 4.59E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00412 Epoxide hydrolase signature 274 296 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00412 Epoxide hydrolase signature 73 88 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00412 Epoxide hydrolase signature 119 132 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00412 Epoxide hydrolase signature 53 71 8.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 2.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 2.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 Hamap MF_01230 Haloalkane dehalogenase [dhmA]. 1 298 55.361 T 28-03-2018 IPR023489 Haloalkane dehalogenase, subfamily 1 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 CP478_RS12475 3e6e54f3d2c80ef29605668f5748b258 300 Pfam PF00561 alpha/beta hydrolase fold 47 176 1.8E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 Pfam PF02567 Phenazine biosynthesis-like protein 139 197 3.9E-6 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 Pfam PF02567 Phenazine biosynthesis-like protein 10 109 1.8E-14 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 PIRSF PIRSF016184 1 154 1.1E-25 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 PIRSF PIRSF016184 144 225 1.7E-5 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 SUPERFAMILY SSF54506 1 220 8.55E-37 T 28-03-2018 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 Gene3D G3DSA:3.10.310.10 1 112 8.9E-19 T 28-03-2018 CP478_RS14885 6f0f7d78391246c4ea78830b4c598c36 228 Gene3D G3DSA:3.10.310.10 113 218 2.4E-21 T 28-03-2018 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 PRINTS PR00163 Rubredoxin signature 36 52 7.7E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 PRINTS PR00163 Rubredoxin signature 6 22 7.7E-8 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 Pfam PF00301 Rubredoxin 7 52 2.5E-22 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 SUPERFAMILY SSF57802 3 57 1.85E-21 T 28-03-2018 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 ProSitePatterns PS00202 Rubredoxin signature. 36 46 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CP478_RS17820 000fc0910c0f776d679c17412725ae58 60 Gene3D G3DSA:2.20.28.10 2 57 5.8E-24 T 28-03-2018 CP478_RS02895 dc1f5350524250016c0963a21fbef14f 220 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 44 165 1.1E-28 T 28-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated CP478_RS02895 dc1f5350524250016c0963a21fbef14f 220 Gene3D G3DSA:3.90.550.10 6 191 7.1E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS02895 dc1f5350524250016c0963a21fbef14f 220 SUPERFAMILY SSF53448 10 204 7.31E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS15405 0833b41035517849e50a18da24e9bcd9 113 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 26 113 5.9E-23 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CP478_RS15405 0833b41035517849e50a18da24e9bcd9 113 Pfam PF09827 CRISPR associated protein Cas2 26 91 2.2E-17 T 28-03-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CP478_RS15405 0833b41035517849e50a18da24e9bcd9 113 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 26 111 14.37 T 28-03-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CP478_RS15405 0833b41035517849e50a18da24e9bcd9 113 SUPERFAMILY SSF143430 25 98 2.35E-19 T 28-03-2018 CP478_RS15405 0833b41035517849e50a18da24e9bcd9 113 Gene3D G3DSA:3.30.70.240 23 113 6.0E-22 T 28-03-2018 CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 Gene3D G3DSA:1.10.287.1060 27 105 2.5E-4 T 28-03-2018 CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 Pfam PF01469 Pentapeptide repeats (8 copies) 328 363 2.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 Pfam PF01469 Pentapeptide repeats (8 copies) 424 460 1.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 Pfam PF01469 Pentapeptide repeats (8 copies) 404 442 7.8E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 Pfam PF00823 PPE family 6 162 4.8E-53 T 28-03-2018 IPR000030 PPE family CP478_RS19445 8848927c5e0688a8f2f16c34e7c1a227 551 SUPERFAMILY SSF140459 4 169 7.85E-53 T 28-03-2018 CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 Gene3D G3DSA:3.30.420.10 4 168 2.6E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 Pfam PF00929 Exonuclease 18 168 1.2E-18 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 SUPERFAMILY SSF52113 229 305 1.5E-8 T 28-03-2018 IPR001357 BRCT domain CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 Gene3D G3DSA:3.40.50.10190 169 306 9.5E-6 T 28-03-2018 IPR001357 BRCT domain CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 SMART SM00479 15 180 8.5E-41 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CP478_RS20275 1ef16fdf8955f901e4088974cb964f4c 329 SUPERFAMILY SSF53098 14 192 2.71E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS11660 f808ca6d400c9ee120b79374ba645510 71 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 11 69 5.1E-20 T 28-03-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module CP478_RS15915 b3e4623cc5787e25df15d6114d7f9e8a 585 Gene3D G3DSA:3.30.200.20 7 81 2.7E-12 T 28-03-2018 CP478_RS15915 b3e4623cc5787e25df15d6114d7f9e8a 585 Pfam PF00069 Protein kinase domain 12 205 2.3E-20 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CP478_RS15915 b3e4623cc5787e25df15d6114d7f9e8a 585 SUPERFAMILY SSF56112 10 257 2.16E-44 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS15915 b3e4623cc5787e25df15d6114d7f9e8a 585 Gene3D G3DSA:1.10.510.10 82 463 5.0E-24 T 28-03-2018 CP478_RS13085 a3b44394b5db2d60cb45beaf64e7b771 272 SUPERFAMILY SSF161098 8 259 6.02E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS13085 a3b44394b5db2d60cb45beaf64e7b771 272 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 8 266 2.4E-116 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CP478_RS13085 a3b44394b5db2d60cb45beaf64e7b771 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 9 264 4.9E-109 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CP478_RS13085 a3b44394b5db2d60cb45beaf64e7b771 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 265 9.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS13085 a3b44394b5db2d60cb45beaf64e7b771 272 Gene3D G3DSA:1.10.3720.10 7 271 1.8E-37 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 Gene3D G3DSA:3.40.30.10 3 69 5.3E-24 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 SUPERFAMILY SSF52833 5 104 5.84E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 PIRSF PIRSF000077 1 104 3.8E-27 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 Gene3D G3DSA:3.40.30.10 70 113 7.0E-5 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 Pfam PF00085 Thioredoxin 5 101 3.2E-26 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 PRINTS PR00421 Thioredoxin family signature 29 38 5.4E-8 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 PRINTS PR00421 Thioredoxin family signature 68 79 5.4E-8 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 PRINTS PR00421 Thioredoxin family signature 21 29 5.4E-8 T 28-03-2018 CP478_RS08060 414a60bacd6e46e1d98227e7d520507b 123 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.8E-33 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CP478_RS06605 1d5f6f35675c9f65b413de11c225e5c8 187 SUPERFAMILY SSF102405 11 183 3.21E-50 T 28-03-2018 CP478_RS06605 1d5f6f35675c9f65b413de11c225e5c8 187 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 11 186 1.2E-78 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CP478_RS06605 1d5f6f35675c9f65b413de11c225e5c8 187 Pfam PF03641 Possible lysine decarboxylase 54 183 2.9E-38 T 28-03-2018 IPR031100 LOG family CP478_RS06605 1d5f6f35675c9f65b413de11c225e5c8 187 Gene3D G3DSA:3.40.50.450 2 185 7.7E-45 T 28-03-2018 CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.9E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 SUPERFAMILY SSF51735 5 262 2.84E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 Pfam PF00106 short chain dehydrogenase 9 200 7.3E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 Gene3D G3DSA:3.40.50.720 1 266 9.7E-59 T 28-03-2018 CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.0E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS05755 e8908d11fc2608d53d41b6ddbc5e3fe3 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 191 1.6E-4 T 28-03-2018 CP478_RS18225 5c1c9b960d572d241537b71337da500c 509 Gene3D G3DSA:1.20.1290.10 326 493 2.1E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS18225 5c1c9b960d572d241537b71337da500c 509 SUPERFAMILY SSF69118 312 486 3.06E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS18225 5c1c9b960d572d241537b71337da500c 509 Pfam PF01548 Transposase 9 94 1.5E-14 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CP478_RS18225 5c1c9b960d572d241537b71337da500c 509 Pfam PF02371 Transposase IS116/IS110/IS902 family 161 246 2.9E-20 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CP478_RS15775 fce4c820e7aa14e4e01324dd8cf5afd8 295 Pfam PF00239 Resolvase, N terminal domain 153 291 3.0E-13 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS15775 fce4c820e7aa14e4e01324dd8cf5afd8 295 Gene3D G3DSA:1.10.1660.20 101 143 0.0013 T 28-03-2018 CP478_RS15775 fce4c820e7aa14e4e01324dd8cf5afd8 295 Gene3D G3DSA:3.40.50.1390 148 295 9.3E-14 T 28-03-2018 CP478_RS15775 fce4c820e7aa14e4e01324dd8cf5afd8 295 SMART SM00857 152 292 7.0E-6 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS15775 fce4c820e7aa14e4e01324dd8cf5afd8 295 SUPERFAMILY SSF53041 151 282 3.14E-13 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS13855 7f286d9f7689fb825a9a8d483fa86e54 306 Gene3D G3DSA:1.10.10.10 3 103 2.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13855 7f286d9f7689fb825a9a8d483fa86e54 306 Gene3D G3DSA:3.40.1350.10 151 290 1.1E-23 T 28-03-2018 CP478_RS13855 7f286d9f7689fb825a9a8d483fa86e54 306 Pfam PF04471 Restriction endonuclease 162 280 4.6E-37 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CP478_RS13855 7f286d9f7689fb825a9a8d483fa86e54 306 SUPERFAMILY SSF52980 166 284 5.9E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS13855 7f286d9f7689fb825a9a8d483fa86e54 306 Pfam PF14338 Mrr N-terminal domain 7 91 2.9E-28 T 28-03-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain CP478_RS19970 aa926722420b3d1e470b0b34a5b98411 387 Pfam PF00437 Type II/IV secretion system protein 57 338 5.3E-70 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CP478_RS19970 aa926722420b3d1e470b0b34a5b98411 387 SUPERFAMILY SSF52540 39 343 1.13E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19970 aa926722420b3d1e470b0b34a5b98411 387 Gene3D G3DSA:3.40.50.300 186 363 5.8E-15 T 28-03-2018 CP478_RS19970 aa926722420b3d1e470b0b34a5b98411 387 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 350 8.5E-157 T 28-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase CP478_RS19970 aa926722420b3d1e470b0b34a5b98411 387 Gene3D G3DSA:3.30.450.90 52 162 3.6E-29 T 28-03-2018 CP478_RS13765 e99e01ef2d55d7496222939a2b5e96d9 153 Pfam PF14367 Domain of unknown function (DUF4411) 3 153 5.2E-39 T 28-03-2018 IPR016541 Uncharacterised conserved protein UCP008505 CP478_RS13765 e99e01ef2d55d7496222939a2b5e96d9 153 SUPERFAMILY SSF88723 5 117 1.79E-5 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13765 e99e01ef2d55d7496222939a2b5e96d9 153 PIRSF PIRSF008505 1 153 8.7E-65 T 28-03-2018 IPR016541 Uncharacterised conserved protein UCP008505 CP478_RS13765 e99e01ef2d55d7496222939a2b5e96d9 153 Gene3D G3DSA:3.40.50.1010 2 130 1.4E-7 T 28-03-2018 IPR029060 PIN domain-like CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 SMART SM00823 Phosphopantetheine attachment site 547 619 4.6E-20 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 SUPERFAMILY SSF56801 6 490 1.05E-115 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 480 8.1E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Pfam PF00550 Phosphopantetheine attachment site 548 615 4.2E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Gene3D G3DSA:2.30.38.10 306 386 8.5E-19 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Gene3D G3DSA:3.30.300.30 389 521 7.6E-22 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Gene3D G3DSA:1.10.1200.10 540 680 1.7E-11 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Gene3D G3DSA:3.40.50.980 157 305 2.0E-32 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 SUPERFAMILY SSF47336 540 624 1.96E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Gene3D G3DSA:3.40.50.980 2 156 5.9E-29 T 28-03-2018 CP478_RS16105 beb14a3476fe7077c7c07f8def8ee5af 705 Pfam PF00501 AMP-binding enzyme 17 390 2.1E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS16435 46b05fa7b270c19bc1f504d239e2dad9 112 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 1 112 2.0E-57 T 28-03-2018 IPR020535 Low molecular weight antigen Cfp6 CP478_RS16435 46b05fa7b270c19bc1f504d239e2dad9 112 Pfam PF10756 Bacterial PH domain 39 109 2.6E-19 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CP478_RS02500 625bbf60dae41317dd99778732a5af3a 286 SUPERFAMILY SSF53335 12 286 8.82E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02500 625bbf60dae41317dd99778732a5af3a 286 Pfam PF02353 Mycolic acid cyclopropane synthetase 6 282 1.2E-112 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02500 625bbf60dae41317dd99778732a5af3a 286 PIRSF PIRSF003085 8 286 7.4E-100 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS02500 625bbf60dae41317dd99778732a5af3a 286 Gene3D G3DSA:3.40.50.150 4 286 2.3E-51 T 28-03-2018 CP478_RS20165 b49dabe3f044f73abe6c54cd4ad6eb67 358 Gene3D G3DSA:1.10.8.300 246 354 1.0E-33 T 28-03-2018 CP478_RS20165 b49dabe3f044f73abe6c54cd4ad6eb67 358 PIRSF PIRSF002849 26 358 1.6E-132 T 28-03-2018 CP478_RS20165 b49dabe3f044f73abe6c54cd4ad6eb67 358 Gene3D G3DSA:3.40.50.300 63 229 6.1E-26 T 28-03-2018 CP478_RS20165 b49dabe3f044f73abe6c54cd4ad6eb67 358 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 82 212 4.2E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CP478_RS20165 b49dabe3f044f73abe6c54cd4ad6eb67 358 SUPERFAMILY SSF52540 45 330 2.34E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 PIRSF PIRSF036289 1 764 1.2E-216 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 SUPERFAMILY SSF48208 279 744 6.8E-110 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 270 1.3E-58 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Gene3D G3DSA:2.60.420.10 681 754 1.2E-18 T 28-03-2018 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Gene3D G3DSA:2.70.98.40 3 273 1.5E-75 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Gene3D G3DSA:1.50.10.10 321 680 1.5E-96 T 28-03-2018 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 699 751 9.1E-13 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 SUPERFAMILY SSF74650 6 270 7.85E-64 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CP478_RS18615 a6d7092016beef772b45747b6b7f0438 787 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 327 694 2.9E-142 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 Gene3D G3DSA:2.40.50.100 6 134 3.5E-43 T 28-03-2018 CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 Pfam PF01597 Glycine cleavage H-protein 8 132 1.9E-40 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 SUPERFAMILY SSF51230 4 132 1.72E-39 T 28-03-2018 IPR011053 Single hybrid motif CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 133 5.0E-47 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CP478_RS09940 f758e8fcb618fbfd33126006500dbf3c 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 133 40.258 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CP478_RS19600 51f6e3e8c82257d71ff21b86d3bb8a92 264 Gene3D G3DSA:2.60.40.10 88 226 8.2E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS06915 7dbd8335c3c6b95f3c4731431c481174 397 SUPERFAMILY SSF55073 213 378 2.51E-34 T 28-03-2018 IPR029787 Nucleotide cyclase CP478_RS06915 7dbd8335c3c6b95f3c4731431c481174 397 SMART SM00044 169 353 2.9E-5 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS06915 7dbd8335c3c6b95f3c4731431c481174 397 Pfam PF16701 Adenylate cyclase regulatory domain 10 194 2.7E-82 T 28-03-2018 IPR032026 Adenylate cyclase regulatory domain CP478_RS06915 7dbd8335c3c6b95f3c4731431c481174 397 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 213 370 5.4E-14 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS06915 7dbd8335c3c6b95f3c4731431c481174 397 Gene3D G3DSA:3.30.70.1230 195 376 6.2E-30 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CP478_RS20315 3f3dd0fad060928b23e50ada70aa5734 470 SUPERFAMILY SSF56176 50 185 2.15E-25 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CP478_RS20315 3f3dd0fad060928b23e50ada70aa5734 470 Gene3D G3DSA:3.30.465.10 67 207 6.7E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CP478_RS20315 3f3dd0fad060928b23e50ada70aa5734 470 SUPERFAMILY SSF55103 160 459 2.05E-13 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CP478_RS20315 3f3dd0fad060928b23e50ada70aa5734 470 Pfam PF01565 FAD binding domain 50 154 1.6E-9 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 Gene3D G3DSA:3.30.1120.10 479 570 3.9E-7 T 28-03-2018 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 Gene3D G3DSA:3.40.720.10 1 423 1.0E-52 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 Pfam PF00884 Sulfatase 5 389 8.2E-59 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 SUPERFAMILY SSF53649 155 436 2.09E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 SUPERFAMILY SSF53649 42 128 2.09E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS16835 d68cdb75247c8aa92b4022ec1d4d4e45 603 SUPERFAMILY SSF53649 473 567 2.09E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS05680 06f7b401b2d91dc55773dfa6e3f3fdf8 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.9E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS05680 06f7b401b2d91dc55773dfa6e3f3fdf8 98 Gene3D G3DSA:1.10.287.1060 1 98 4.7E-14 T 28-03-2018 CP478_RS05680 06f7b401b2d91dc55773dfa6e3f3fdf8 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 5.6E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS05680 06f7b401b2d91dc55773dfa6e3f3fdf8 98 SUPERFAMILY SSF140453 4 97 3.79E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS17980 bc420a18b81e7191234979279310bc4e 548 Gene3D G3DSA:3.90.226.10 281 539 1.0E-72 T 28-03-2018 CP478_RS17980 bc420a18b81e7191234979279310bc4e 548 Gene3D G3DSA:3.90.226.10 12 280 6.8E-79 T 28-03-2018 CP478_RS17980 bc420a18b81e7191234979279310bc4e 548 SUPERFAMILY SSF52096 28 276 1.64E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS17980 bc420a18b81e7191234979279310bc4e 548 SUPERFAMILY SSF52096 294 548 2.74E-87 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS17980 bc420a18b81e7191234979279310bc4e 548 Pfam PF01039 Carboxyl transferase domain 50 545 5.8E-199 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS10620 45c8e3c76478848488c952cb4b457123 71 Gene3D G3DSA:1.10.1220.10 1 36 5.6E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS10620 45c8e3c76478848488c952cb4b457123 71 SUPERFAMILY SSF47598 1 57 1.56E-12 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS01245 40005610838138fdd87e902bdea289e5 326 Gene3D G3DSA:3.20.20.140 2 323 1.5E-57 T 28-03-2018 CP478_RS01245 40005610838138fdd87e902bdea289e5 326 SUPERFAMILY SSF51556 4 320 8.4E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS01245 40005610838138fdd87e902bdea289e5 326 Pfam PF02126 Phosphotriesterase family 11 320 1.5E-146 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 CP478_RS01245 40005610838138fdd87e902bdea289e5 326 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 28-03-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 Pfam PF00486 Transcriptional regulatory protein, C terminal 179 253 9.8E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 Gene3D G3DSA:3.40.50.2300 22 154 9.9E-39 T 28-03-2018 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 SUPERFAMILY SSF46894 157 254 3.12E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 Pfam PF00072 Response regulator receiver domain 34 143 4.4E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 SMART SM00448 32 143 1.1E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 SUPERFAMILY SSF52172 27 155 4.41E-41 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 Gene3D G3DSA:1.10.10.10 155 257 5.0E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05665 dcdfb5709f1bd37cfeb0ea6ff3ab39d0 257 SMART SM00862 179 253 1.6E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CP478_RS15365 b9a3b3966f49609d5f0a3211979c4d70 384 Pfam PF00665 Integrase core domain 141 252 2.3E-11 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS15365 b9a3b3966f49609d5f0a3211979c4d70 384 Gene3D G3DSA:3.30.420.10 135 361 8.2E-19 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS15365 b9a3b3966f49609d5f0a3211979c4d70 384 SUPERFAMILY SSF53098 142 278 2.4E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS08120 16b89a36cbe5a631f525af999a440a8e 280 Gene3D G3DSA:3.40.960.10 177 276 5.0E-7 T 28-03-2018 CP478_RS01235 a578a5f3c4bce26c8788866c3281b74f 137 Pfam PF01850 PIN domain 5 120 3.6E-10 T 28-03-2018 IPR002716 PIN domain CP478_RS01235 a578a5f3c4bce26c8788866c3281b74f 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 126 11.661 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS01235 a578a5f3c4bce26c8788866c3281b74f 137 Gene3D G3DSA:3.40.50.1010 2 136 1.6E-17 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01235 a578a5f3c4bce26c8788866c3281b74f 137 SUPERFAMILY SSF88723 1 119 2.69E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06335 fe1f67554562475a90cc5154b9af425e 147 SUPERFAMILY SSF50475 6 142 5.05E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS06335 fe1f67554562475a90cc5154b9af425e 147 Gene3D G3DSA:2.30.110.10 1 143 1.8E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS06335 fe1f67554562475a90cc5154b9af425e 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 141 4.9E-38 T 28-03-2018 IPR019920 F420-binding domain, putative CP478_RS06335 fe1f67554562475a90cc5154b9af425e 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 3.1E-16 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 Gene3D G3DSA:3.30.200.20 5 102 4.2E-34 T 28-03-2018 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 Pfam PF01259 SAICAR synthetase 11 260 3.0E-96 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 Gene3D G3DSA:3.30.470.20 103 238 2.2E-52 T 28-03-2018 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 SUPERFAMILY SSF56104 6 288 2.45E-93 T 28-03-2018 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 10 286 2.2E-68 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 8 286 23.45 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 ProSitePatterns PS01058 SAICAR synthetase signature 2. 194 202 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS04240 21013cfa802c366635d7a69400b97cd4 297 ProSitePatterns PS01057 SAICAR synthetase signature 1. 95 109 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 SUPERFAMILY SSF55931 108 445 1.37E-115 T 28-03-2018 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 Gene3D G3DSA:3.10.20.70 1 105 1.1E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 SUPERFAMILY SSF54368 7 104 2.62E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 Pfam PF00120 Glutamine synthetase, catalytic domain 107 443 1.8E-126 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 3.2E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 Gene3D G3DSA:3.30.590.10 106 446 7.3E-115 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CP478_RS12075 aca50c9faaf8407f5face99108938bc2 446 SMART SM01230 106 357 1.0E-122 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Gene3D G3DSA:1.10.287.1060 22 111 9.7E-4 T 28-03-2018 CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF00823 PPE family 5 162 4.4E-53 T 28-03-2018 IPR000030 PPE family CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2736 2773 2.7E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2607 2644 4.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 924 961 1.4E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 262 300 1.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2697 2734 4.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 963 1002 8.7E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1589 1626 9.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1578 1617 2.5E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1385 1423 3.3E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1984 2017 1.0E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 841 879 9.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1539 1577 8.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 774 807 1.2E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2172 2211 8.0E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2050 2088 7.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2133 2170 4.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 196 229 1.4E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 884 922 3.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2653 2691 2.6E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1559 1596 6.7E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 305 343 1.0E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 345 383 9.6E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 1499 1537 1.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2093 2131 1.2E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 384 423 1.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 Pfam PF01469 Pentapeptide repeats (8 copies) 2775 2814 2.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18320 eb2a97ef4381f345dc794520305d500f 3157 SUPERFAMILY SSF140459 2 173 6.54E-55 T 28-03-2018 CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 PIRSF PIRSF000545 1 312 3.2E-141 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 311 7.6E-120 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 92 229 2.2E-11 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 SUPERFAMILY SSF52540 5 310 1.18E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 Hamap MF_00215 Pantothenate kinase [coaA]. 1 312 174.857 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CP478_RS06000 4542030477bcf7cfae5bb2321ad98296 312 Gene3D G3DSA:3.40.50.300 7 311 2.2E-49 T 28-03-2018 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 SUPERFAMILY SSF52518 403 605 3.93E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 426 578 1.6E-48 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 463 482 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 39 204 2.2E-56 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Gene3D G3DSA:3.40.50.970 32 233 2.0E-60 T 28-03-2018 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 228 363 4.1E-50 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 SUPERFAMILY SSF52518 36 219 4.79E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 SUPERFAMILY SSF52467 220 394 8.79E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 38 601 3.2E-232 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Gene3D G3DSA:3.40.50.970 387 599 2.0E-50 T 28-03-2018 CP478_RS16430 935cfb68f4710deaf77b734cf31ce5ed 618 Gene3D G3DSA:3.40.50.1220 234 386 6.2E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS08355 606d8d63fe2c658595c9b25a7cb4ee32 347 Gene3D G3DSA:3.40.50.150 119 327 1.2E-30 T 28-03-2018 CP478_RS08355 606d8d63fe2c658595c9b25a7cb4ee32 347 Pfam PF08241 Methyltransferase domain 165 259 3.1E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS08355 606d8d63fe2c658595c9b25a7cb4ee32 347 SUPERFAMILY SSF53335 144 341 1.15E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 21 191 5.7E-37 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 Pfam PF02527 rRNA small subunit methyltransferase G 19 194 6.3E-54 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 SUPERFAMILY SSF53335 20 202 1.17E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 Gene3D G3DSA:3.40.50.150 12 222 5.5E-29 T 28-03-2018 CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 PIRSF PIRSF003078 10 210 1.0E-41 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CP478_RS21415 489ca6441d6165526117c24a7169d2ce 224 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 8 190 21.424 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CP478_RS16150 52ae979115d241f0d614418df4a2166d 243 Pfam PF05050 Methyltransferase FkbM domain 45 214 2.7E-16 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS16150 52ae979115d241f0d614418df4a2166d 243 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 42 190 4.5E-32 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS16150 52ae979115d241f0d614418df4a2166d 243 SUPERFAMILY SSF53335 33 216 2.49E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16150 52ae979115d241f0d614418df4a2166d 243 Gene3D G3DSA:3.40.50.150 23 229 5.0E-22 T 28-03-2018 CP478_RS16130 ca2feee65042c802b45883f77b12f801 270 Pfam PF08241 Methyltransferase domain 85 178 1.2E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS16130 ca2feee65042c802b45883f77b12f801 270 SUPERFAMILY SSF53335 19 191 4.52E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16130 ca2feee65042c802b45883f77b12f801 270 Gene3D G3DSA:3.40.50.150 13 254 3.0E-26 T 28-03-2018 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 SUPERFAMILY SSF140490 334 433 1.16E-37 T 28-03-2018 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 177 192 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 SMART SM00928 338 383 8.8E-25 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 351 362 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 229 3.2E-45 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 Pfam PF10531 SLBB domain 254 300 7.5E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 SUPERFAMILY SSF142984 252 333 4.05E-22 T 28-03-2018 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 340 423 1.6E-31 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 SUPERFAMILY SSF142019 19 249 8.37E-82 T 28-03-2018 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 12 424 9.8E-199 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17250 fdf44673832d4c35dcd1a7a6f2866a7a 445 Gene3D G3DSA:3.10.560.10 247 335 2.3E-4 T 28-03-2018 CP478_RS06745 784e5dbb726bcbff05282c1148e90b2d 180 Pfam PF06210 Protein of unknown function (DUF1003) 39 140 8.3E-36 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CP478_RS01775 73aa353eb0bbcd81b68869286977f17d 261 SUPERFAMILY SSF109854 13 144 6.41E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS01775 73aa353eb0bbcd81b68869286977f17d 261 Gene3D G3DSA:1.20.120.450 4 146 7.3E-17 T 28-03-2018 CP478_RS01775 73aa353eb0bbcd81b68869286977f17d 261 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 18 235 1.5E-33 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS01775 73aa353eb0bbcd81b68869286977f17d 261 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 20 140 2.8E-22 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS01775 73aa353eb0bbcd81b68869286977f17d 261 Pfam PF07398 MDMPI C-terminal domain 153 253 2.8E-18 T 28-03-2018 IPR010872 MDMPI C-terminal CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 SUPERFAMILY SSF54843 8 120 3.53E-40 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 ProSitePatterns PS00464 Ribosomal protein L22 signature. 93 117 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 Gene3D G3DSA:3.90.470.10 1 191 3.9E-47 T 28-03-2018 CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 15 117 3.9E-49 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 Pfam PF00237 Ribosomal protein L22p/L17e 15 117 5.9E-35 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CP478_RS03830 cba8dad1f98aab371c6782b70ea0a2fa 197 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 11 120 28.724 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.6E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.6E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.6E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.6E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 Gene3D G3DSA:3.30.70.1450 136 211 3.3E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 Pfam PF02080 TrkA-C domain 149 211 1.2E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 SUPERFAMILY SSF116726 142 207 2.62E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 Gene3D G3DSA:3.40.50.720 1 135 8.6E-22 T 28-03-2018 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 Pfam PF02254 TrkA-N domain 3 116 3.3E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CP478_RS14760 b696ebf4b58b7d408e585eba5edd9b9a 227 SUPERFAMILY SSF51735 1 132 1.18E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 Gene3D G3DSA:3.40.50.720 54 248 3.0E-54 T 28-03-2018 CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 Gene3D G3DSA:3.40.50.720 9 53 4.3E-7 T 28-03-2018 CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 SUPERFAMILY SSF51735 16 245 9.25E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS19395 e2c00faf8e1bdb6c8f6ad8aa1074c6a9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 245 7.3E-53 T 28-03-2018 CP478_RS07990 230e550113f54417f0f65946a96e1d09 261 PIRSF PIRSF006648 3 260 3.3E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CP478_RS07990 230e550113f54417f0f65946a96e1d09 261 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 38 261 3.4E-81 T 28-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 CP478_RS07990 230e550113f54417f0f65946a96e1d09 261 Pfam PF01061 ABC-2 type transporter 34 231 1.3E-11 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CP478_RS04810 c11ddf9d784d9528cdd7b06512fb5d30 94 Pfam PF10801 Protein of unknown function (DUF2537) 10 87 1.3E-29 T 28-03-2018 IPR024244 Protein of unknown function DUF2537 CP478_RS04810 c11ddf9d784d9528cdd7b06512fb5d30 94 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 1 71 1.0E-16 T 28-03-2018 IPR024244 Protein of unknown function DUF2537 CP478_RS14075 52789196e7519b9d8f4e773edcdb41da 884 Pfam PF14403 Circularly permuted ATP-grasp type 2 115 487 4.8E-126 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CP478_RS14075 52789196e7519b9d8f4e773edcdb41da 884 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 539 861 5.0E-67 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CP478_RS14075 52789196e7519b9d8f4e773edcdb41da 884 SUPERFAMILY SSF56059 106 253 6.36E-6 T 28-03-2018 CP478_RS14075 52789196e7519b9d8f4e773edcdb41da 884 SUPERFAMILY SSF56059 360 410 6.36E-6 T 28-03-2018 CP478_RS19735 24777bbf028ce15eea65f20a10f9c472 184 Gene3D G3DSA:3.30.1310.10 50 138 0.0012 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS19535 96567d7ad1f5394efe05be26fe957564 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19535 96567d7ad1f5394efe05be26fe957564 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19535 96567d7ad1f5394efe05be26fe957564 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 8.1E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS19535 96567d7ad1f5394efe05be26fe957564 199 Gene3D G3DSA:1.10.357.10 5 199 4.3E-37 T 28-03-2018 CP478_RS19535 96567d7ad1f5394efe05be26fe957564 199 SUPERFAMILY SSF46689 15 77 3.49E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS21040 ed597e73dbf71253108b5d8991fef69a 302 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 4.1E-17 T 28-03-2018 IPR001727 Gdt1 family CP478_RS21040 ed597e73dbf71253108b5d8991fef69a 302 Pfam PF01169 Uncharacterized protein family UPF0016 107 180 6.1E-20 T 28-03-2018 IPR001727 Gdt1 family CP478_RS11265 38fd86f265832581ade786e478884877 508 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 218 1.3E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 249 457 1.4E-31 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 5 236 1.7E-61 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CP478_RS11265 38fd86f265832581ade786e478884877 508 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS11265 38fd86f265832581ade786e478884877 508 Gene3D G3DSA:3.40.1010.10 4 156 3.1E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 Gene3D G3DSA:3.40.1010.10 246 365 3.6E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 249 492 3.8E-77 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CP478_RS11265 38fd86f265832581ade786e478884877 508 Gene3D G3DSA:3.30.950.10 366 490 2.2E-46 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 SUPERFAMILY SSF53790 245 479 3.4E-46 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11265 38fd86f265832581ade786e478884877 508 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 103 135 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CP478_RS11265 38fd86f265832581ade786e478884877 508 SUPERFAMILY SSF53790 4 238 9.29E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS05760 941c8eb6dc7d18c96f8c7f75d1e87658 251 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 8 152 3.7E-13 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CP478_RS05760 941c8eb6dc7d18c96f8c7f75d1e87658 251 Gene3D G3DSA:1.10.10.10 195 251 1.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05760 941c8eb6dc7d18c96f8c7f75d1e87658 251 SUPERFAMILY SSF46955 195 244 2.29E-9 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS05760 941c8eb6dc7d18c96f8c7f75d1e87658 251 Pfam PF12728 Helix-turn-helix domain 195 245 2.1E-7 T 28-03-2018 CP478_RS01785 03bfbee5befedc72b75c3d9aa081a42f 288 Gene3D G3DSA:3.90.550.10 1 288 4.1E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01785 03bfbee5befedc72b75c3d9aa081a42f 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 3.7E-151 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CP478_RS01785 03bfbee5befedc72b75c3d9aa081a42f 288 SUPERFAMILY SSF53448 1 286 8.11E-83 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01785 03bfbee5befedc72b75c3d9aa081a42f 288 Pfam PF00483 Nucleotidyl transferase 3 236 7.8E-65 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 165 285 1.6E-22 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 SUPERFAMILY SSF51735 1 157 2.46E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 Gene3D G3DSA:3.40.50.720 1 164 5.7E-20 T 28-03-2018 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 SUPERFAMILY SSF48179 165 285 7.14E-26 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 Pfam PF02558 Ketopantoate reductase PanE/ApbA 1 141 7.1E-27 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 1 286 1.1E-51 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CP478_RS14105 3ba78129b70737adb2f75e07e2082617 291 Gene3D G3DSA:1.10.1040.10 165 289 7.0E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CP478_RS13480 14f707e0a0a23de09c715305ab9b7aec 207 Gene3D G3DSA:3.40.30.10 64 167 3.0E-13 T 28-03-2018 CP478_RS13480 14f707e0a0a23de09c715305ab9b7aec 207 Gene3D G3DSA:3.40.30.10 8 63 1.7E-11 T 28-03-2018 CP478_RS13480 14f707e0a0a23de09c715305ab9b7aec 207 SUPERFAMILY SSF52833 11 167 9.35E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS13480 14f707e0a0a23de09c715305ab9b7aec 207 Pfam PF01323 DSBA-like thioredoxin domain 12 165 8.2E-12 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF00823 PPE family 5 162 4.9E-59 T 28-03-2018 IPR000030 PPE family CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Gene3D G3DSA:1.10.287.1060 19 111 7.5E-7 T 28-03-2018 CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 2015 2053 2.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 1439 1477 2.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 1482 1519 2.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 2058 2095 2.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 254 292 2.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 337 374 6.0E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 376 415 1.8E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 297 335 1.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 802 840 1.1E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 1561 1600 1.8E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 1522 1559 6.2E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 2137 2176 1.8E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 792 830 2.2E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 187 220 2.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 750 787 4.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 Pfam PF01469 Pentapeptide repeats (8 copies) 2098 2135 6.2E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18305 f3335e45e8da430dfca55f7b65d35e25 2523 SUPERFAMILY SSF140459 3 171 3.92E-59 T 28-03-2018 CP478_RS10075 a76f8f0f41d017c9e8ef2b0599256397 208 Pfam PF01774 UreD urease accessory protein 27 158 1.8E-15 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CP478_RS11980 f01f469cf83e98a3bc88531ff5358b43 118 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 100 117 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CP478_RS11980 f01f469cf83e98a3bc88531ff5358b43 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 15 115 2.9E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CP478_RS11980 f01f469cf83e98a3bc88531ff5358b43 118 SUPERFAMILY SSF89360 14 108 1.16E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CP478_RS11980 f01f469cf83e98a3bc88531ff5358b43 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 14 118 8.2E-36 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CP478_RS11980 f01f469cf83e98a3bc88531ff5358b43 118 Gene3D G3DSA:2.60.300.12 14 118 6.1E-33 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CP478_RS06175 a8856b886e0a3bd4aa8f3431cd802cc5 451 Pfam PF02720 Domain of unknown function (DUF222) 37 360 6.7E-108 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS06175 a8856b886e0a3bd4aa8f3431cd802cc5 451 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 1 95 3.0E-39 T 28-03-2018 CP478_RS06175 a8856b886e0a3bd4aa8f3431cd802cc5 451 SMART SM00507 351 403 1.9E-4 T 28-03-2018 IPR003615 HNH nuclease CP478_RS19050 3d10114fa938d85d635001a0975639e5 220 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 104 220 5.0E-13 T 28-03-2018 CP478_RS19050 3d10114fa938d85d635001a0975639e5 220 Pfam PF14041 LppP/LprE lipoprotein 118 204 1.9E-23 T 28-03-2018 IPR025971 LppP/LprE lipoprotein CP478_RS10465 e1d5aba4b4087dfdc14c86b5e44ea160 446 SUPERFAMILY SSF56601 289 394 1.4E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS10465 e1d5aba4b4087dfdc14c86b5e44ea160 446 SUPERFAMILY SSF56601 42 252 1.4E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS10465 e1d5aba4b4087dfdc14c86b5e44ea160 446 Pfam PF00144 Beta-lactamase 59 394 1.6E-62 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS10465 e1d5aba4b4087dfdc14c86b5e44ea160 446 Gene3D G3DSA:3.40.710.10 44 397 1.7E-66 T 28-03-2018 CP478_RS15920 73c08da8348a3a7d713e1c984ab0b8cb 370 Gene3D G3DSA:2.30.40.10 289 369 5.7E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS15920 73c08da8348a3a7d713e1c984ab0b8cb 370 Gene3D G3DSA:2.30.40.10 18 72 3.8E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS15920 73c08da8348a3a7d713e1c984ab0b8cb 370 Gene3D G3DSA:3.20.20.140 73 288 8.0E-24 T 28-03-2018 CP478_RS15920 73c08da8348a3a7d713e1c984ab0b8cb 370 Pfam PF01979 Amidohydrolase family 55 330 1.2E-13 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CP478_RS15920 73c08da8348a3a7d713e1c984ab0b8cb 370 SUPERFAMILY SSF51556 58 333 1.24E-62 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS04355 020a179fa8385fbc10cf265652f18e50 218 Pfam PF13302 Acetyltransferase (GNAT) domain 16 163 8.5E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS04355 020a179fa8385fbc10cf265652f18e50 218 SUPERFAMILY SSF55729 10 168 3.09E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS04355 020a179fa8385fbc10cf265652f18e50 218 Gene3D G3DSA:3.40.630.30 1 218 8.5E-37 T 28-03-2018 CP478_RS09250 935d0490597a36ebd409f715d6c8098a 307 Gene3D G3DSA:2.60.200.30 155 276 1.2E-35 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CP478_RS09250 935d0490597a36ebd409f715d6c8098a 307 Hamap MF_00361 NAD kinase [nadK]. 5 299 29.933 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CP478_RS09250 935d0490597a36ebd409f715d6c8098a 307 Gene3D G3DSA:3.40.50.10330 5 154 6.5E-33 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CP478_RS09250 935d0490597a36ebd409f715d6c8098a 307 Pfam PF01513 ATP-NAD kinase 7 283 1.4E-77 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CP478_RS09250 935d0490597a36ebd409f715d6c8098a 307 SUPERFAMILY SSF111331 6 305 1.7E-80 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CP478_RS02475 83a5ac81c6fda606d44761760aa0598d 190 Gene3D G3DSA:1.20.1290.10 38 190 4.9E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS02475 83a5ac81c6fda606d44761760aa0598d 190 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 129 1.1E-13 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS02475 83a5ac81c6fda606d44761760aa0598d 190 SUPERFAMILY SSF69118 7 189 5.45E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS19855 f4f96b69911221f04c5bfa99452e6a1d 248 SUPERFAMILY SSF52540 107 221 7.21E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19855 f4f96b69911221f04c5bfa99452e6a1d 248 Pfam PF01695 IstB-like ATP binding protein 108 223 2.0E-38 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CP478_RS19855 f4f96b69911221f04c5bfa99452e6a1d 248 PIRSF PIRSF003073 8 240 1.4E-66 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein CP478_RS00195 845846715164c4453e40c8b61a9c874e 131 SUPERFAMILY SSF54427 7 127 1.51E-22 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS00195 845846715164c4453e40c8b61a9c874e 131 Gene3D G3DSA:3.10.450.50 1 130 4.6E-19 T 28-03-2018 CP478_RS00195 845846715164c4453e40c8b61a9c874e 131 Pfam PF12680 SnoaL-like domain 10 115 1.1E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS07465 42e77302c0d93d39bd562f7206cddc01 340 Pfam PF00296 Luciferase-like monooxygenase 15 314 2.4E-61 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS07465 42e77302c0d93d39bd562f7206cddc01 340 SUPERFAMILY SSF51679 17 321 5.89E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS07465 42e77302c0d93d39bd562f7206cddc01 340 Gene3D G3DSA:3.20.20.30 11 338 7.2E-56 T 28-03-2018 CP478_RS07465 42e77302c0d93d39bd562f7206cddc01 340 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 24 339 2.2E-158 T 28-03-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted CP478_RS10510 a4b1fe4aaee5d37e63bf1df146b46e78 165 SUPERFAMILY SSF52833 1 161 6.41E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS10510 a4b1fe4aaee5d37e63bf1df146b46e78 165 Pfam PF08534 Redoxin 20 160 7.7E-26 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CP478_RS10510 a4b1fe4aaee5d37e63bf1df146b46e78 165 Gene3D G3DSA:3.40.30.10 7 165 1.3E-22 T 28-03-2018 CP478_RS10510 a4b1fe4aaee5d37e63bf1df146b46e78 165 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 164 37.374 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CP478_RS10510 a4b1fe4aaee5d37e63bf1df146b46e78 165 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CP478_RS09325 3b3e961448734b59f8730f725292b4b5 278 Pfam PF02616 Segregation and condensation protein ScpA 40 264 7.6E-86 T 28-03-2018 IPR003768 Segregation and condensation protein A CP478_RS09325 3b3e961448734b59f8730f725292b4b5 278 Gene3D G3DSA:1.10.10.580 192 263 4.0E-12 T 28-03-2018 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 SUPERFAMILY SSF53738 26 200 5.49E-44 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 SUPERFAMILY SSF53738 193 291 1.02E-19 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 304 424 2.3E-17 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Gene3D G3DSA:3.40.120.10 23 199 2.6E-52 T 28-03-2018 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Gene3D G3DSA:3.40.120.10 200 314 2.7E-24 T 28-03-2018 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 130 144 2.7E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 228 2.7E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 276 291 2.7E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 131 140 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 SUPERFAMILY SSF53738 284 430 6.36E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Gene3D G3DSA:3.30.310.50 440 532 9.6E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 207 291 1.1E-19 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 486 503 2.1E-5 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Gene3D G3DSA:3.40.120.10 315 429 4.6E-33 T 28-03-2018 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 36 170 8.4E-40 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS18120 9993ad0769e753d2318a710abbdaeb09 534 SUPERFAMILY SSF55957 420 503 6.93E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CP478_RS10290 7d4d5eb53927ccb19a7679bcc7f3ad62 203 SMART SM00867 25 200 6.5E-13 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CP478_RS10290 7d4d5eb53927ccb19a7679bcc7f3ad62 203 SUPERFAMILY SSF101874 24 201 2.09E-22 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CP478_RS10290 7d4d5eb53927ccb19a7679bcc7f3ad62 203 Gene3D G3DSA:2.40.128.110 25 203 4.0E-28 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CP478_RS10290 7d4d5eb53927ccb19a7679bcc7f3ad62 203 Pfam PF04264 YceI-like domain 53 197 1.1E-11 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CP478_RS00460 16f3ecc14b85d1964f03bb72898f8864 159 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 155 2.2E-24 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00460 16f3ecc14b85d1964f03bb72898f8864 159 SUPERFAMILY SSF56770 33 157 1.57E-47 T 28-03-2018 CP478_RS00460 16f3ecc14b85d1964f03bb72898f8864 159 Gene3D G3DSA:3.40.50.700 30 159 8.6E-26 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 217 1.1E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Gene3D G3DSA:1.20.140.10 232 400 1.2E-38 T 28-03-2018 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 122 1.2E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 SUPERFAMILY SSF47203 234 397 3.06E-24 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 SUPERFAMILY SSF56645 3 247 1.31E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Gene3D G3DSA:2.40.110.10 126 231 1.4E-29 T 28-03-2018 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Gene3D G3DSA:1.10.540.10 1 124 2.2E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS19160 9477c8151e382885f2ef1aa233d4f2b2 400 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 392 7.2E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS05415 4ae320411d2680be8ffa16f0b0f0cf29 197 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 186 9.1E-33 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CP478_RS05415 4ae320411d2680be8ffa16f0b0f0cf29 197 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 186 1.8E-46 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CP478_RS05415 4ae320411d2680be8ffa16f0b0f0cf29 197 SUPERFAMILY SSF100950 5 189 3.07E-36 T 28-03-2018 CP478_RS05415 4ae320411d2680be8ffa16f0b0f0cf29 197 Gene3D G3DSA:3.40.50.10420 1 193 9.9E-46 T 28-03-2018 CP478_RS05415 4ae320411d2680be8ffa16f0b0f0cf29 197 PIRSF PIRSF006806 1 189 7.3E-53 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CP478_RS18680 07bec7b3fcbf237b5243cd397f6b5006 299 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 14 58 4.4E-17 T 28-03-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region CP478_RS00705 58377e773713f54dc4a864ca5c1d5a6d 340 SUPERFAMILY SSF53474 47 328 1.54E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00705 58377e773713f54dc4a864ca5c1d5a6d 340 Pfam PF00756 Putative esterase 61 322 8.6E-73 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS00705 58377e773713f54dc4a864ca5c1d5a6d 340 Gene3D G3DSA:3.40.50.1820 45 328 1.0E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 Gene3D G3DSA:3.30.70.920 55 149 5.3E-18 T 28-03-2018 CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 SUPERFAMILY SSF54909 68 146 1.21E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 Gene3D G3DSA:1.10.10.10 1 54 3.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 SUPERFAMILY SSF46785 4 65 9.79E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 Pfam PF01037 Lrp/AsnC ligand binding domain 78 141 1.3E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 4.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS18035 90fa7e0aca71792bff25fed9d1fd462a 150 SMART SM00344 5 112 1.8E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 297 446 1.8E-61 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Pfam PF04679 ATP dependent DNA ligase C terminal region 657 751 1.4E-22 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Pfam PF01068 ATP dependent DNA ligase domain 461 637 5.2E-27 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Gene3D G3DSA:3.30.470.30 431 580 9.7E-34 T 28-03-2018 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 9 261 8.2E-92 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 SUPERFAMILY SSF56091 455 638 2.18E-39 T 28-03-2018 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Gene3D G3DSA:3.30.1490.70 581 627 1.5E-14 T 28-03-2018 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Gene3D G3DSA:2.40.50.140 628 753 8.6E-29 T 28-03-2018 CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 460 757 5.3E-98 T 28-03-2018 IPR014146 DNA ligase D, ligase domain CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 SUPERFAMILY SSF50249 640 758 3.34E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS05115 3eb2b18f4f0ab6be7efc340f55c937c0 759 Pfam PF13298 DNA polymerase Ligase (LigD) 329 432 5.5E-38 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CP478_RS14430 78228e8593d514a94aab9b1fb94108ae 778 SUPERFAMILY SSF140459 8 84 7.06E-26 T 28-03-2018 CP478_RS14430 78228e8593d514a94aab9b1fb94108ae 778 Pfam PF00934 PE family 1 92 4.2E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09705 a49a20d6b9cd3ebbedebc9f8f4157cdf 724 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 132 692 1.4E-92 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS09705 a49a20d6b9cd3ebbedebc9f8f4157cdf 724 Gene3D G3DSA:3.20.20.80 169 703 3.2E-168 T 28-03-2018 CP478_RS09705 a49a20d6b9cd3ebbedebc9f8f4157cdf 724 SUPERFAMILY SSF51445 632 709 2.46E-136 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS09705 a49a20d6b9cd3ebbedebc9f8f4157cdf 724 SUPERFAMILY SSF51445 172 602 2.46E-136 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS09705 a49a20d6b9cd3ebbedebc9f8f4157cdf 724 Pfam PF02446 4-alpha-glucanotransferase 179 687 7.3E-116 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 SUPERFAMILY SSF53335 8 228 1.32E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 1.0E-73 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 Gene3D G3DSA:3.40.50.150 2 227 6.3E-35 T 28-03-2018 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 24 39 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 227 1.2E-58 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 33.613 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CP478_RS02985 2a52b1a90de6e3d447051934916c3b1d 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CP478_RS04875 45f790956ca53d172c95af7221f12a51 325 SUPERFAMILY SSF53335 14 286 1.66E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS04875 45f790956ca53d172c95af7221f12a51 325 Gene3D G3DSA:3.40.50.150 1 286 5.7E-51 T 28-03-2018 CP478_RS04875 45f790956ca53d172c95af7221f12a51 325 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 277 6.0E-91 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS04875 45f790956ca53d172c95af7221f12a51 325 Pfam PF04072 Leucine carboxyl methyltransferase 19 196 2.1E-56 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS10445 ab050c57b1fc58f8fd3924cfe1e62ebd 154 SUPERFAMILY SSF55961 6 149 6.29E-19 T 28-03-2018 CP478_RS10445 ab050c57b1fc58f8fd3924cfe1e62ebd 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 148 1.2E-21 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS10445 ab050c57b1fc58f8fd3924cfe1e62ebd 154 Gene3D G3DSA:3.30.530.20 1 154 4.1E-20 T 28-03-2018 IPR023393 START-like domain CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 Gene3D G3DSA:3.40.50.980 4 178 1.3E-28 T 28-03-2018 CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 Gene3D G3DSA:2.30.38.10 381 464 9.8E-19 T 28-03-2018 CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 SUPERFAMILY SSF56801 7 575 3.92E-95 T 28-03-2018 CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 Gene3D G3DSA:3.40.50.980 179 355 8.6E-26 T 28-03-2018 CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 Gene3D G3DSA:3.30.300.30 465 573 2.4E-14 T 28-03-2018 CP478_RS08345 81507d778a5d3c828656bc1d4130649d 583 Pfam PF00501 AMP-binding enzyme 13 471 1.6E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS02795 8f1564b92d4a542a6c0bb42a05fec0ae 461 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CP478_RS02795 8f1564b92d4a542a6c0bb42a05fec0ae 461 Pfam PF00324 Amino acid permease 27 430 1.7E-105 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CP478_RS02795 8f1564b92d4a542a6c0bb42a05fec0ae 461 PIRSF PIRSF006060 5 459 1.4E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS02425 9322f73b0dd0e5ff0bc0690e962ec96c 304 SUPERFAMILY SSF52096 3 280 3.1E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS02425 9322f73b0dd0e5ff0bc0690e962ec96c 304 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 118 138 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS02425 9322f73b0dd0e5ff0bc0690e962ec96c 304 Gene3D G3DSA:3.90.226.10 2 288 6.6E-53 T 28-03-2018 CP478_RS02425 9322f73b0dd0e5ff0bc0690e962ec96c 304 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 239 2.6E-28 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Pfam PF01479 S4 domain 92 136 4.0E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 9.3E-82 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 SMART SM00363 91 153 8.6E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 5.4E-28 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Gene3D G3DSA:1.10.1050.10 140 201 3.3E-12 T 28-03-2018 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 SUPERFAMILY SSF55174 3 201 1.18E-60 T 28-03-2018 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Gene3D G3DSA:3.10.290.10 97 139 1.9E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 SMART SM01390 3 90 8.6E-43 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Gene3D G3DSA:1.10.1050.10 1 96 2.7E-39 T 28-03-2018 CP478_RS18925 42cf06f4937c870f39d67b71a05734c2 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 33.852 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 202 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 SUPERFAMILY SSF51735 17 306 6.54E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 Pfam PF00106 short chain dehydrogenase 23 226 7.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS02335 c0b8bdde4e828c9ee2ea5d546f124984 311 Gene3D G3DSA:3.40.50.720 6 311 5.8E-64 T 28-03-2018 CP478_RS12930 0e3655845fd194fb2a4aada28a8a1fbf 95 SUPERFAMILY SSF140459 42 94 3.92E-11 T 28-03-2018 CP478_RS12930 0e3655845fd194fb2a4aada28a8a1fbf 95 Pfam PF00934 PE family 35 94 2.7E-15 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS21420 dc753f94fd8d3f4ad96162564d7aaaba 187 SUPERFAMILY SSF82708 133 186 2.16E-9 T 28-03-2018 IPR001374 R3H domain GO:0003676 CP478_RS21420 dc753f94fd8d3f4ad96162564d7aaaba 187 Gene3D G3DSA:3.30.1370.50 119 187 1.3E-18 T 28-03-2018 IPR001374 R3H domain GO:0003676 CP478_RS21420 dc753f94fd8d3f4ad96162564d7aaaba 187 Gene3D G3DSA:3.30.300.20 40 117 1.3E-20 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS21420 dc753f94fd8d3f4ad96162564d7aaaba 187 SMART SM00393 108 187 9.7E-26 T 28-03-2018 IPR001374 R3H domain GO:0003676 CP478_RS21420 dc753f94fd8d3f4ad96162564d7aaaba 187 Pfam PF01424 R3H domain 127 185 1.4E-14 T 28-03-2018 IPR001374 R3H domain GO:0003676 CP478_RS08695 4882f48cdbfd9759dc24e6d6e36ea2b0 237 Pfam PF02720 Domain of unknown function (DUF222) 53 158 3.7E-17 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS08695 4882f48cdbfd9759dc24e6d6e36ea2b0 237 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 16 102 1.0E-20 T 28-03-2018 CP478_RS01515 173408bbce3b9500ab107f9fbd41fa1a 536 Gene3D G3DSA:1.10.287.1060 21 112 5.0E-7 T 28-03-2018 CP478_RS01515 173408bbce3b9500ab107f9fbd41fa1a 536 SUPERFAMILY SSF140459 3 175 2.88E-61 T 28-03-2018 CP478_RS01515 173408bbce3b9500ab107f9fbd41fa1a 536 Pfam PF00823 PPE family 6 162 1.1E-58 T 28-03-2018 IPR000030 PPE family CP478_RS09265 a75d8919a09ffd1574c62a7595a46379 314 Pfam PF11382 Copper transport outer membrane protein, MctB 1 311 2.0E-93 T 28-03-2018 IPR021522 Copper transporter MctB GO:0006810 CP478_RS04155 6713225a217edef5a4a58af873c780a2 68 Pfam PF13459 4Fe-4S single cluster domain 5 63 9.0E-10 T 28-03-2018 CP478_RS04155 6713225a217edef5a4a58af873c780a2 68 Gene3D G3DSA:3.30.70.20 2 66 3.4E-6 T 28-03-2018 CP478_RS04155 6713225a217edef5a4a58af873c780a2 68 SUPERFAMILY SSF54862 4 64 9.56E-12 T 28-03-2018 CP478_RS20765 8b3163a35503bac888987fd66c44473d 336 Gene3D G3DSA:3.40.50.1820 67 327 5.7E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20765 8b3163a35503bac888987fd66c44473d 336 SMART SM01110 70 323 3.7E-56 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS20765 8b3163a35503bac888987fd66c44473d 336 Pfam PF01083 Cutinase 110 275 7.9E-16 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS20765 8b3163a35503bac888987fd66c44473d 336 SUPERFAMILY SSF53474 71 276 6.61E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18405 ebf12605ca90350f7f89c1ced92f858e 122 SUPERFAMILY SSF49879 16 112 1.17E-16 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS18405 ebf12605ca90350f7f89c1ced92f858e 122 SMART SM00240 25 75 3.7E-5 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS18405 ebf12605ca90350f7f89c1ced92f858e 122 Gene3D G3DSA:2.60.200.20 2 106 3.3E-14 T 28-03-2018 CP478_RS18405 ebf12605ca90350f7f89c1ced92f858e 122 Pfam PF00498 FHA domain 26 89 2.6E-10 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 219 2.8E-80 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 SUPERFAMILY SSF52317 3 220 1.05E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 205 1.7E-37 T 28-03-2018 CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 PIRSF PIRSF001586 1 223 1.0E-78 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 Gene3D G3DSA:3.40.50.880 1 222 7.2E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 SMART SM01211 2 221 2.5E-124 T 28-03-2018 CP478_RS04285 ca8fb4c12e0a7b2dc027953497ea7a58 224 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 219 38.904 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 SUPERFAMILY SSF48264 64 474 7.99E-93 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 310 336 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 380 404 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 340 358 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 290 307 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 412 422 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 422 445 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00463 E-class P450 group I signature 74 93 1.1E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 415 424 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00385 P450 superfamily signature 422 433 1.4E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00385 P450 superfamily signature 341 352 1.4E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00385 P450 superfamily signature 413 422 1.4E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 PRINTS PR00385 P450 superfamily signature 301 318 1.4E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 Pfam PF00067 Cytochrome P450 71 466 9.0E-63 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS20130 cd57bad3e3e6096a68a53c61b7667201 476 Gene3D G3DSA:1.10.630.10 56 476 8.0E-98 T 28-03-2018 CP478_RS09225 2ea609bac9889e5df2ce6aab4f335397 127 Pfam PF05305 Protein of unknown function (DUF732) 26 116 3.7E-20 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS09225 2ea609bac9889e5df2ce6aab4f335397 127 Gene3D G3DSA:3.40.1190.20 7 127 8.0E-6 T 28-03-2018 IPR029056 Ribokinase-like CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 14 389 7.4E-113 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Gene3D G3DSA:3.40.50.720 11 151 3.6E-45 T 28-03-2018 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Gene3D G3DSA:1.10.1740.10 304 387 1.7E-28 T 28-03-2018 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 15 385 44.225 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 SUPERFAMILY SSF51735 14 151 4.38E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 PIRSF PIRSF006205 12 391 5.8E-138 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Pfam PF13288 DXP reductoisomerase C-terminal domain 263 380 1.2E-34 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 147 230 7.6E-34 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 135 2.6E-37 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 SUPERFAMILY SSF69055 294 387 7.32E-27 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CP478_RS15690 0296896fc828612d205d1fad5c594be9 413 SUPERFAMILY SSF55347 129 265 1.28E-53 T 28-03-2018 CP478_RS17840 a9034f842551de583fa39312d4aa15a3 462 Gene3D G3DSA:3.50.50.60 1 380 3.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17840 a9034f842551de583fa39312d4aa15a3 462 SUPERFAMILY SSF51905 1 197 5.29E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17840 a9034f842551de583fa39312d4aa15a3 462 SUPERFAMILY SSF51905 303 403 5.29E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07785 4a3c03bd0ff54126fb0161c485cff9b3 325 Pfam PF14527 WhiA LAGLIDADG-like domain 125 216 1.5E-23 T 28-03-2018 CP478_RS07785 4a3c03bd0ff54126fb0161c485cff9b3 325 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 2 302 7.0E-107 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CP478_RS07785 4a3c03bd0ff54126fb0161c485cff9b3 325 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 1 304 28.928 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CP478_RS07785 4a3c03bd0ff54126fb0161c485cff9b3 325 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 102 4.8E-22 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CP478_RS07785 4a3c03bd0ff54126fb0161c485cff9b3 325 Pfam PF02650 WhiA C-terminal HTH domain 219 301 3.3E-20 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CP478_RS02410 b54808100347db2f1ec974a9de8310ee 518 Pfam PF00823 PPE family 9 165 1.8E-58 T 28-03-2018 IPR000030 PPE family CP478_RS02410 b54808100347db2f1ec974a9de8310ee 518 SUPERFAMILY SSF140459 6 178 1.12E-60 T 28-03-2018 CP478_RS02410 b54808100347db2f1ec974a9de8310ee 518 Gene3D G3DSA:1.10.287.1060 25 108 4.9E-8 T 28-03-2018 CP478_RS14815 2fed39f36926fd854cd4e9adc9d8704d 265 Gene3D G3DSA:3.30.420.40 134 264 8.8E-25 T 28-03-2018 CP478_RS14815 2fed39f36926fd854cd4e9adc9d8704d 265 SUPERFAMILY SSF53067 21 258 9.98E-31 T 28-03-2018 CP478_RS14815 2fed39f36926fd854cd4e9adc9d8704d 265 Gene3D G3DSA:3.30.420.40 6 133 1.4E-21 T 28-03-2018 CP478_RS14815 2fed39f36926fd854cd4e9adc9d8704d 265 Pfam PF00480 ROK family 22 176 3.4E-13 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CP478_RS14200 22697c7dee7f485a3929947c20f972ca 543 Pfam PF00934 PE family 1 93 8.1E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS14200 22697c7dee7f485a3929947c20f972ca 543 SUPERFAMILY SSF140459 8 83 5.23E-24 T 28-03-2018 CP478_RS14200 22697c7dee7f485a3929947c20f972ca 543 Gene3D G3DSA:1.10.287.1060 1 99 0.0011 T 28-03-2018 CP478_RS18375 f61693a121f4e4ddd2a8e545f605e9d8 129 Pfam PF05305 Protein of unknown function (DUF732) 15 108 4.6E-24 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS03660 67448842bed7a87ec053bf38cc7111bc 142 Pfam PF05423 Mycobacterium membrane protein 5 142 1.5E-64 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS13925 1f155e3362f86486f0bf9c98c8c584ad 135 Gene3D G3DSA:1.10.287.1060 40 131 5.2E-8 T 28-03-2018 CP478_RS15515 7c5024a6eedbedff8e59f36334acd06b 336 Pfam PF01368 DHH family 36 177 1.0E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CP478_RS15515 7c5024a6eedbedff8e59f36334acd06b 336 Gene3D G3DSA:3.90.1640.10 13 217 5.9E-36 T 28-03-2018 CP478_RS15515 7c5024a6eedbedff8e59f36334acd06b 336 Pfam PF02272 DHHA1 domain 205 335 1.1E-13 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CP478_RS15515 7c5024a6eedbedff8e59f36334acd06b 336 SUPERFAMILY SSF64182 36 321 2.35E-55 T 28-03-2018 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 Gene3D G3DSA:1.10.357.10 79 204 6.0E-6 T 28-03-2018 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 3.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 SUPERFAMILY SSF46689 20 90 6.67E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 Gene3D G3DSA:1.10.260.40 58 78 0.0018 T 28-03-2018 CP478_RS17815 55ae2f0ac54574af0b98b76da1e06bd6 211 Gene3D G3DSA:1.10.10.60 9 57 3.6E-14 T 28-03-2018 CP478_RS19635 9cadb51686cfdbc8f14e006214990409 275 SMART SM00644 27 172 6.6E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS19635 9cadb51686cfdbc8f14e006214990409 275 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 37 172 2.4E-13 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS19635 9cadb51686cfdbc8f14e006214990409 275 SUPERFAMILY SSF55846 22 185 6.62E-29 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS19635 9cadb51686cfdbc8f14e006214990409 275 Gene3D G3DSA:3.40.80.10 22 192 1.2E-21 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CP478_RS02595 6c47ef5dcf861a2f57187b6e7ead3b10 183 SUPERFAMILY SSF69635 6 138 3.92E-27 T 28-03-2018 CP478_RS02595 6c47ef5dcf861a2f57187b6e7ead3b10 183 Gene3D G3DSA:3.30.1460.10 5 146 1.5E-39 T 28-03-2018 CP478_RS02595 6c47ef5dcf861a2f57187b6e7ead3b10 183 Pfam PF10722 Putative bacterial sensory transduction regulator 11 136 1.9E-23 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN CP478_RS04195 2a3e1456c222a2b44b827c53dcbc7cbb 144 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 100 9.1E-9 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CP478_RS04195 2a3e1456c222a2b44b827c53dcbc7cbb 144 SUPERFAMILY SSF69118 4 106 4.89E-18 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS04195 2a3e1456c222a2b44b827c53dcbc7cbb 144 Gene3D G3DSA:1.20.1290.10 6 144 1.1E-19 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS05800 8c66116aa0796e4fa2ab84ae09808fd0 254 Pfam PF04248 Domain of unknown function (DUF427) 142 235 7.5E-30 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CP478_RS05800 8c66116aa0796e4fa2ab84ae09808fd0 254 Pfam PF04248 Domain of unknown function (DUF427) 25 96 3.2E-8 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CP478_RS08015 576c4f42b28441da5250edb58499f948 397 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 99 377 1.5E-85 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CP478_RS08015 576c4f42b28441da5250edb58499f948 397 SUPERFAMILY SSF101960 28 386 8.89E-87 T 28-03-2018 CP478_RS08015 576c4f42b28441da5250edb58499f948 397 Pfam PF01458 Uncharacterized protein family (UPF0051) 135 360 5.0E-68 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 Pfam PF13452 N-terminal half of MaoC dehydratase 8 125 2.4E-7 T 28-03-2018 CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 SUPERFAMILY SSF54637 160 273 5.3E-32 T 28-03-2018 IPR029069 HotDog domain CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 Gene3D G3DSA:3.10.129.10 11 158 3.2E-35 T 28-03-2018 CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 Pfam PF01575 MaoC like domain 161 271 7.9E-33 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 SUPERFAMILY SSF54637 8 155 4.76E-35 T 28-03-2018 IPR029069 HotDog domain CP478_RS18550 1bdb554e2011812ea7d92c911662bcaf 290 Gene3D G3DSA:3.10.129.10 159 285 2.3E-30 T 28-03-2018 CP478_RS07245 aff5ac9475795eb434d2e3d49ed87ab4 223 Pfam PF01939 Endonuclease NucS 1 223 1.1E-103 T 28-03-2018 IPR002793 Endonuclease NucS CP478_RS07245 aff5ac9475795eb434d2e3d49ed87ab4 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 215 31.362 T 28-03-2018 IPR002793 Endonuclease NucS CP478_RS08550 24517f046d61e11c5a04fa308092f2c2 134 SUPERFAMILY SSF88723 1 122 2.24E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS08550 24517f046d61e11c5a04fa308092f2c2 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 129 15.571 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS08550 24517f046d61e11c5a04fa308092f2c2 134 Pfam PF01850 PIN domain 2 124 2.1E-17 T 28-03-2018 IPR002716 PIN domain CP478_RS08550 24517f046d61e11c5a04fa308092f2c2 134 Gene3D G3DSA:3.40.50.1010 1 134 2.9E-21 T 28-03-2018 IPR029060 PIN domain-like CP478_RS21425 50322dbf0b4567852062951cba1e0d50 366 Pfam PF02096 60Kd inner membrane protein 40 273 1.1E-48 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CP478_RS21425 50322dbf0b4567852062951cba1e0d50 366 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 40 273 1.4E-56 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CP478_RS03995 8ab22a68c050482ed78c2ffb79d79a3e 70 SUPERFAMILY SSF140459 3 42 7.06E-5 T 28-03-2018 CP478_RS03995 8ab22a68c050482ed78c2ffb79d79a3e 70 Pfam PF00934 PE family 6 44 4.7E-6 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06525 4f94fa694989ddfb5e1977335a8ada17 304 Gene3D G3DSA:3.40.50.1820 10 304 6.7E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06525 4f94fa694989ddfb5e1977335a8ada17 304 Pfam PF00561 alpha/beta hydrolase fold 37 133 6.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS06525 4f94fa694989ddfb5e1977335a8ada17 304 SUPERFAMILY SSF53474 14 296 6.1E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 358 2.1E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 SUPERFAMILY SSF56645 2 191 8.64E-34 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 Gene3D G3DSA:1.20.140.10 216 360 3.8E-33 T 28-03-2018 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 Gene3D G3DSA:1.10.540.10 1 112 4.5E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 113 3.7E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 Gene3D G3DSA:2.40.110.10 113 215 2.3E-6 T 28-03-2018 CP478_RS10515 092f93e50eed23e74e26154ec60d1d99 363 SUPERFAMILY SSF47203 217 357 2.9E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 PIRSF PIRSF017901 26 430 1.3E-105 T 28-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 32 410 1.6E-174 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 21 408 29.017 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 SUPERFAMILY SSF55931 300 379 3.53E-45 T 28-03-2018 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 SUPERFAMILY SSF55931 40 259 3.53E-45 T 28-03-2018 CP478_RS20235 3f2a2745a15f5ff6a27151ad9b55ca95 432 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 46 354 5.6E-96 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Gene3D G3DSA:1.10.530.10 267 362 5.2E-33 T 28-03-2018 CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Pfam PF03990 Domain of unknown function (DUF348) 141 180 6.0E-6 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Pfam PF03990 Domain of unknown function (DUF348) 85 114 3.8E-6 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Pfam PF03990 Domain of unknown function (DUF348) 27 65 6.8E-8 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Pfam PF06737 Transglycosylase-like domain 283 355 4.6E-34 T 28-03-2018 IPR010618 Transglycosylase-like CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 SMART SM01208 194 272 9.7E-17 T 28-03-2018 IPR011098 G5 domain CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Pfam PF07501 G5 domain 198 271 1.6E-16 T 28-03-2018 IPR011098 G5 domain CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 SUPERFAMILY SSF53955 278 361 1.46E-31 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS05520 196e9e4888df8adf7d328a03b33805c5 362 Gene3D G3DSA:2.20.230.10 193 266 9.1E-14 T 28-03-2018 CP478_RS10495 ae1531e5bb4302a4b3edeb50b8b9622c 214 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 8 208 3.2E-73 T 28-03-2018 IPR017519 Conserved hypothetical protein CHP03085 CP478_RS10495 ae1531e5bb4302a4b3edeb50b8b9622c 214 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 189 5.8E-33 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS10495 ae1531e5bb4302a4b3edeb50b8b9622c 214 SUPERFAMILY SSF109854 10 120 6.87E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS10495 ae1531e5bb4302a4b3edeb50b8b9622c 214 Gene3D G3DSA:1.20.120.450 6 197 1.3E-16 T 28-03-2018 CP478_RS11415 8455909a771736a2842f80c6dca9db8f 332 Pfam PF13280 WYL domain 154 326 1.8E-28 T 28-03-2018 IPR026881 WYL domain CP478_RS11720 3a5b4cb762b3188cc576c92cd18f5ac1 524 Pfam PF01098 Cell cycle protein 58 412 8.0E-126 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CP478_RS11720 3a5b4cb762b3188cc576c92cd18f5ac1 524 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 59 411 1.4E-121 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CP478_RS11720 3a5b4cb762b3188cc576c92cd18f5ac1 524 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 370 394 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CP478_RS16870 1e651b793564dfaa4e8c81a1a41982f8 308 Pfam PF07859 alpha/beta hydrolase fold 72 272 5.4E-42 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS16870 1e651b793564dfaa4e8c81a1a41982f8 308 SUPERFAMILY SSF53474 50 296 2.87E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16870 1e651b793564dfaa4e8c81a1a41982f8 308 Gene3D G3DSA:3.40.50.1820 13 304 1.7E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS13800 935b98aaa43802e55f36e50ccf933f13 492 SUPERFAMILY SSF140459 8 84 4.18E-21 T 28-03-2018 CP478_RS13800 935b98aaa43802e55f36e50ccf933f13 492 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 231 242 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 CP478_RS13800 935b98aaa43802e55f36e50ccf933f13 492 Pfam PF00934 PE family 2 93 7.3E-28 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS13800 935b98aaa43802e55f36e50ccf933f13 492 Gene3D G3DSA:2.40.70.10 212 471 5.9E-4 T 28-03-2018 IPR021109 Aspartic peptidase domain CP478_RS16145 384afdf643de08fe5bfd6e3b6096c9b5 321 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 131 267 2.0E-33 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS16145 384afdf643de08fe5bfd6e3b6096c9b5 321 SUPERFAMILY SSF53335 48 297 5.16E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16145 384afdf643de08fe5bfd6e3b6096c9b5 321 Pfam PF05050 Methyltransferase FkbM domain 133 290 1.7E-15 T 28-03-2018 IPR006342 Methyltransferase FkbM CP478_RS16145 384afdf643de08fe5bfd6e3b6096c9b5 321 Gene3D G3DSA:3.40.50.150 112 314 6.1E-39 T 28-03-2018 CP478_RS01555 50fe7eccf99177b354d5bf9c6db33654 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 96 1.0E-48 T 28-03-2018 CP478_RS01555 50fe7eccf99177b354d5bf9c6db33654 96 Gene3D G3DSA:1.10.287.1060 1 96 1.0E-12 T 28-03-2018 CP478_RS01555 50fe7eccf99177b354d5bf9c6db33654 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 91 5.7E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS01555 50fe7eccf99177b354d5bf9c6db33654 96 SUPERFAMILY SSF140453 2 95 3.92E-21 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS01555 50fe7eccf99177b354d5bf9c6db33654 96 Pfam PF06013 Proteins of 100 residues with WXG 3 87 1.9E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 Pfam PF02445 Quinolinate synthetase A protein 37 341 2.0E-107 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 Gene3D G3DSA:3.40.50.10800 116 208 5.6E-24 T 28-03-2018 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 35 342 1.6E-84 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 Gene3D G3DSA:3.40.50.10800 32 111 6.2E-20 T 28-03-2018 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 SUPERFAMILY SSF142754 34 342 7.06E-101 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 Hamap MF_00568 Quinolinate synthase A [nadA]. 32 342 41.876 T 28-03-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CP478_RS08725 c7d70a1ce4ecc898b088248fcc0344ef 349 Gene3D G3DSA:3.40.50.10800 209 324 2.0E-28 T 28-03-2018 CP478_RS09180 14ceec97a49336d61291504a6e11991b 330 SUPERFAMILY SSF102114 74 244 1.83E-34 T 28-03-2018 CP478_RS09180 14ceec97a49336d61291504a6e11991b 330 Pfam PF04055 Radical SAM superfamily 87 217 1.1E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CP478_RS09180 14ceec97a49336d61291504a6e11991b 330 Gene3D G3DSA:3.20.20.70 76 253 1.9E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS09180 14ceec97a49336d61291504a6e11991b 330 Pfam PF13353 4Fe-4S single cluster domain 75 163 7.3E-7 T 28-03-2018 CP478_RS00720 1255b5c8180650b49c787719507072a5 360 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 44 360 4.0E-72 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CP478_RS00720 1255b5c8180650b49c787719507072a5 360 SUPERFAMILY SSF51679 44 360 2.62E-62 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS00720 1255b5c8180650b49c787719507072a5 360 Gene3D G3DSA:3.20.20.30 38 360 1.8E-62 T 28-03-2018 CP478_RS00720 1255b5c8180650b49c787719507072a5 360 TIGRFAM TIGR04465 ArgArg_F420: TAT-translocated F420-dependent dehydrogenase, FGD2 family 2 360 2.0E-221 T 28-03-2018 IPR031017 TAT-translocated F420-dependent dehydrogenase, FGD2 family CP478_RS00720 1255b5c8180650b49c787719507072a5 360 Pfam PF00296 Luciferase-like monooxygenase 49 281 1.2E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS18410 e733c9c7027dc279ad1bc658f7d67d69 183 Pfam PF13599 Pentapeptide repeats (9 copies) 48 122 3.5E-11 T 28-03-2018 IPR001646 Pentapeptide repeat CP478_RS18410 e733c9c7027dc279ad1bc658f7d67d69 183 Gene3D G3DSA:2.160.20.80 2 182 2.3E-36 T 28-03-2018 CP478_RS18410 e733c9c7027dc279ad1bc658f7d67d69 183 SUPERFAMILY SSF141571 3 179 3.63E-44 T 28-03-2018 CP478_RS11800 67761b97193b039038e562a3758843a4 206 Pfam PF08445 FR47-like protein 104 184 5.4E-7 T 28-03-2018 IPR013653 FR47-like GO:0016747 CP478_RS11800 67761b97193b039038e562a3758843a4 206 SUPERFAMILY SSF55729 123 201 7.62E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS11800 67761b97193b039038e562a3758843a4 206 Gene3D G3DSA:3.40.630.30 13 203 2.0E-12 T 28-03-2018 CP478_RS09650 60ca9c867ab7e7350fb9246acc70b602 428 Gene3D G3DSA:3.40.630.10 36 428 8.8E-38 T 28-03-2018 CP478_RS09650 60ca9c867ab7e7350fb9246acc70b602 428 Pfam PF04389 Peptidase family M28 248 418 3.1E-13 T 28-03-2018 IPR007484 Peptidase M28 CP478_RS09650 60ca9c867ab7e7350fb9246acc70b602 428 SUPERFAMILY SSF53187 247 427 4.79E-27 T 28-03-2018 CP478_RS09650 60ca9c867ab7e7350fb9246acc70b602 428 SUPERFAMILY SSF53187 39 87 4.79E-27 T 28-03-2018 CP478_RS09650 60ca9c867ab7e7350fb9246acc70b602 428 SUPERFAMILY SSF53187 144 184 4.79E-27 T 28-03-2018 CP478_RS18280 0d6a789e007c36dcfacbc790fbef2954 210 Gene3D G3DSA:3.40.50.1820 1 203 5.3E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18280 0d6a789e007c36dcfacbc790fbef2954 210 Pfam PF12697 Alpha/beta hydrolase family 6 193 1.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS18280 0d6a789e007c36dcfacbc790fbef2954 210 SUPERFAMILY SSF53474 2 202 2.54E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 Gene3D G3DSA:2.40.50.100 20 82 2.8E-26 T 28-03-2018 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 Pfam PF01016 Ribosomal L27 protein 2 80 2.1E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.0E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.0E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.0E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 2.0E-17 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 SUPERFAMILY SSF110324 2 80 4.19E-31 T 28-03-2018 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.098 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS13340 2b7caa7e49b055f7092549740cdd9a39 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 5.9E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS07800 eff21ad6cdcf5e3001a8cd518bde45d7 420 Gene3D G3DSA:3.40.50.1820 107 417 6.8E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07800 eff21ad6cdcf5e3001a8cd518bde45d7 420 SUPERFAMILY SSF53474 139 411 5.5E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07800 eff21ad6cdcf5e3001a8cd518bde45d7 420 Pfam PF07859 alpha/beta hydrolase fold 182 390 7.0E-19 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 Pfam PF12849 PBP superfamily domain 48 336 2.1E-56 T 28-03-2018 IPR024370 PBP domain CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 SUPERFAMILY SSF53850 50 369 5.12E-82 T 28-03-2018 CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 Gene3D G3DSA:3.40.190.10 140 311 1.7E-45 T 28-03-2018 CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 Gene3D G3DSA:3.40.190.10 46 139 2.3E-4 T 28-03-2018 CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 51 369 4.2E-120 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS05065 45065bb065b48a08c4b216146f5e435f 370 PIRSF PIRSF002756 8 370 1.7E-107 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CP478_RS21290 d23523486221e31f8c07b31dca0db3dd 302 SUPERFAMILY SSF53955 210 279 2.06E-8 T 28-03-2018 IPR023346 Lysozyme-like domain CP478_RS21290 d23523486221e31f8c07b31dca0db3dd 302 Gene3D G3DSA:1.10.530.10 174 292 5.5E-11 T 28-03-2018 CP478_RS16955 d705c26ec4c063c96288460955597b3a 106 Gene3D G3DSA:2.30.30.110 1 105 1.2E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS16955 d705c26ec4c063c96288460955597b3a 106 SUPERFAMILY SSF50118 4 105 4.41E-19 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS16955 d705c26ec4c063c96288460955597b3a 106 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 102 3.1E-15 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS03470 c03d968caeebf6396bdabdb7efcfbf4b 301 Gene3D G3DSA:3.40.50.150 11 296 2.5E-49 T 28-03-2018 CP478_RS03470 c03d968caeebf6396bdabdb7efcfbf4b 301 Pfam PF02353 Mycolic acid cyclopropane synthetase 13 290 4.2E-120 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03470 c03d968caeebf6396bdabdb7efcfbf4b 301 SUPERFAMILY SSF53335 22 297 4.3E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03470 c03d968caeebf6396bdabdb7efcfbf4b 301 PIRSF PIRSF003085 1 301 2.6E-98 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS10450 3a60b184990e1d7056d983d7d6f3b957 287 SUPERFAMILY SSF69593 37 270 1.15E-15 T 28-03-2018 CP478_RS10450 3a60b184990e1d7056d983d7d6f3b957 287 PIRSF PIRSF016753 5 276 3.4E-90 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted CP478_RS10450 3a60b184990e1d7056d983d7d6f3b957 287 Pfam PF01553 Acyltransferase 47 172 2.0E-17 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS10450 3a60b184990e1d7056d983d7d6f3b957 287 Gene3D G3DSA:3.40.1130.10 27 277 1.5E-17 T 28-03-2018 CP478_RS10450 3a60b184990e1d7056d983d7d6f3b957 287 SMART SM00563 60 176 2.0E-17 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS16820 63819038fd8ab3723a5b79a6070ae815 424 SMART SM00507 314 364 4.2E-5 T 28-03-2018 IPR003615 HNH nuclease CP478_RS16820 63819038fd8ab3723a5b79a6070ae815 424 Gene3D G3DSA:3.40.1800.10 304 378 3.3E-7 T 28-03-2018 CP478_RS16820 63819038fd8ab3723a5b79a6070ae815 424 Pfam PF02720 Domain of unknown function (DUF222) 25 323 5.0E-13 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS10150 fe1dc355c28d21975ce85c102998d41f 494 SUPERFAMILY SSF53901 233 259 5.04E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS10150 fe1dc355c28d21975ce85c102998d41f 494 SUPERFAMILY SSF53901 29 123 5.04E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS10150 fe1dc355c28d21975ce85c102998d41f 494 Gene3D G3DSA:3.40.47.10 252 394 6.2E-10 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS10150 fe1dc355c28d21975ce85c102998d41f 494 Gene3D G3DSA:3.40.47.10 1 251 7.3E-11 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS10150 fe1dc355c28d21975ce85c102998d41f 494 SUPERFAMILY SSF53901 282 395 1.03E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS15215 39155b17ae57533a63d4ffd6706ee813 156 SUPERFAMILY SSF55961 5 156 9.78E-23 T 28-03-2018 CP478_RS15215 39155b17ae57533a63d4ffd6706ee813 156 Gene3D G3DSA:3.30.530.20 1 156 4.3E-27 T 28-03-2018 IPR023393 START-like domain CP478_RS15215 39155b17ae57533a63d4ffd6706ee813 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 154 2.3E-19 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS07195 fd915e8eebe4ceda0e241a6e3df04832 193 SUPERFAMILY SSF89028 7 184 2.94E-57 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CP478_RS07195 fd915e8eebe4ceda0e241a6e3df04832 193 Pfam PF01923 Cobalamin adenosyltransferase 8 175 2.6E-57 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CP478_RS07195 fd915e8eebe4ceda0e241a6e3df04832 193 Gene3D G3DSA:1.20.1200.10 17 190 2.0E-55 T 28-03-2018 CP478_RS07195 fd915e8eebe4ceda0e241a6e3df04832 193 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 2.6E-49 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CP478_RS07195 fd915e8eebe4ceda0e241a6e3df04832 193 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 146 4.0E-64 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CP478_RS14960 672b431f72b9182ffeb42f42c485f555 450 Pfam PF03993 Domain of Unknown Function (DUF349) 140 213 3.1E-11 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CP478_RS14960 672b431f72b9182ffeb42f42c485f555 450 Pfam PF03993 Domain of Unknown Function (DUF349) 294 366 1.5E-17 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CP478_RS14960 672b431f72b9182ffeb42f42c485f555 450 Pfam PF03993 Domain of Unknown Function (DUF349) 217 289 3.8E-19 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CP478_RS13335 99106042e5c808499fde716173df75c6 479 Pfam PF09269 Domain of unknown function (DUF1967) 366 434 1.1E-24 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CP478_RS13335 99106042e5c808499fde716173df75c6 479 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 338 1.2E-122 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 Pfam PF01018 GTP1/OBG 5 158 1.1E-50 T 28-03-2018 IPR006169 GTP1/OBG domain CP478_RS13335 99106042e5c808499fde716173df75c6 479 Gene3D G3DSA:3.40.50.300 159 347 6.8E-30 T 28-03-2018 CP478_RS13335 99106042e5c808499fde716173df75c6 479 SUPERFAMILY SSF82051 4 157 3.14E-47 T 28-03-2018 IPR006169 GTP1/OBG domain CP478_RS13335 99106042e5c808499fde716173df75c6 479 Gene3D G3DSA:2.70.210.12 3 156 1.1E-50 T 28-03-2018 IPR006169 GTP1/OBG domain CP478_RS13335 99106042e5c808499fde716173df75c6 479 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 SUPERFAMILY SSF102741 364 436 3.66E-22 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CP478_RS13335 99106042e5c808499fde716173df75c6 479 SUPERFAMILY SSF52540 161 359 1.94E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13335 99106042e5c808499fde716173df75c6 479 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 366 435 1.6E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CP478_RS13335 99106042e5c808499fde716173df75c6 479 Hamap MF_01454 GTPase Obg [obg]. 3 340 43.59 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 Pfam PF01926 50S ribosome-binding GTPase 161 292 2.1E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS13335 99106042e5c808499fde716173df75c6 479 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.7E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CP478_RS20655 752ec216b724200861835871876f7027 178 Pfam PF10759 Protein of unknown function (DUF2587) 32 171 3.1E-78 T 28-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 CP478_RS03745 39787a922ae8fd034c21570b16741aeb 103 TIGRFAM TIGR03967 mycofact_MftB: putative mycofactocin binding protein MftB 18 97 2.0E-28 T 28-03-2018 IPR023850 Putative mycofactocin binding protein MftB CP478_RS05750 31377d340661d230c598bea3ee895361 148 SUPERFAMILY SSF46785 8 130 1.48E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05750 31377d340661d230c598bea3ee895361 148 Pfam PF12802 MarR family 33 95 1.2E-11 T 28-03-2018 CP478_RS05750 31377d340661d230c598bea3ee895361 148 SMART SM00347 28 132 1.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS05750 31377d340661d230c598bea3ee895361 148 Gene3D G3DSA:1.10.10.10 5 148 7.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05750 31377d340661d230c598bea3ee895361 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS05750 31377d340661d230c598bea3ee895361 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CP478_RS04825 5293e43f550ebf4a8f8a7518da1f5e7f 340 Gene3D G3DSA:1.20.1260.10 73 311 8.9E-17 T 28-03-2018 IPR012347 Ferritin-related CP478_RS04825 5293e43f550ebf4a8f8a7518da1f5e7f 340 SUPERFAMILY SSF47240 35 240 5.8E-7 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS04825 5293e43f550ebf4a8f8a7518da1f5e7f 340 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 19 303 5.9E-108 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF CP478_RS21155 ece637ccb2c64672e2f43276afd6de2a 747 Gene3D G3DSA:3.40.50.300 371 731 1.9E-20 T 28-03-2018 CP478_RS21155 ece637ccb2c64672e2f43276afd6de2a 747 Pfam PF01580 FtsK/SpoIIIE family 431 637 6.9E-47 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS21155 ece637ccb2c64672e2f43276afd6de2a 747 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 705 2.0E-238 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CP478_RS21155 ece637ccb2c64672e2f43276afd6de2a 747 SUPERFAMILY SSF52540 433 707 2.05E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 33 235 1.1E-23 T 28-03-2018 IPR001099 Chalcone/stilbene synthase, N-terminal CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 Gene3D G3DSA:3.40.47.10 31 254 1.3E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 Gene3D G3DSA:3.40.47.10 255 393 1.4E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 SUPERFAMILY SSF53901 27 389 1.76E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 PIRSF PIRSF000451 18 393 1.3E-114 T 28-03-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 CP478_RS07525 7bfc26060b2fe62b2640fdf3510259b3 393 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 251 389 2.1E-21 T 28-03-2018 IPR012328 Chalcone/stilbene synthase, C-terminal CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Gene3D G3DSA:3.10.580.10 321 463 1.4E-18 T 28-03-2018 CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 3 458 7.7E-211 T 28-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 SMART SM00116 343 396 0.0051 T 28-03-2018 IPR000644 CBS domain CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 SMART SM00116 413 458 0.58 T 28-03-2018 IPR000644 CBS domain CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 1.7E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 SUPERFAMILY SSF54631 329 459 2.53E-18 T 28-03-2018 CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 SUPERFAMILY SSF53686 1 317 9.69E-91 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Gene3D G3DSA:3.40.50.1100 146 316 5.0E-49 T 28-03-2018 CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Gene3D G3DSA:3.40.50.1100 38 145 5.6E-34 T 28-03-2018 CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Pfam PF00571 CBS domain 343 395 1.8E-6 T 28-03-2018 IPR000644 CBS domain CP478_RS05905 14ddf9303dd961f15f4b13362474651f 464 Pfam PF00571 CBS domain 408 458 2.2E-6 T 28-03-2018 IPR000644 CBS domain CP478_RS16760 29a88d2353e28fa0b7695ef79f93b3b7 758 Pfam PF02554 Carbon starvation protein CstA 67 442 8.4E-157 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CP478_RS16760 29a88d2353e28fa0b7695ef79f93b3b7 758 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 503 633 7.0E-33 T 28-03-2018 IPR025299 CstA, C-terminal domain CP478_RS20035 3f35f91158db0aa603c090c3780d1e29 172 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 32 145 5.4E-30 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CP478_RS00415 ef5c90dc8ca12a72c5892e1f634396f4 390 Gene3D G3DSA:3.40.640.10 62 272 1.6E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS00415 ef5c90dc8ca12a72c5892e1f634396f4 390 Gene3D G3DSA:3.90.1150.10 273 388 2.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS00415 ef5c90dc8ca12a72c5892e1f634396f4 390 SUPERFAMILY SSF53383 24 387 3.54E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS00415 ef5c90dc8ca12a72c5892e1f634396f4 390 Pfam PF00155 Aminotransferase class I and II 98 381 1.5E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS05830 69a08f62d531cc1de73583d473d623a8 285 SUPERFAMILY SSF52151 4 81 1.88E-30 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS05830 69a08f62d531cc1de73583d473d623a8 285 SUPERFAMILY SSF52151 112 212 1.88E-30 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS05830 69a08f62d531cc1de73583d473d623a8 285 Pfam PF01734 Patatin-like phospholipase 7 203 1.9E-17 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CP478_RS05830 69a08f62d531cc1de73583d473d623a8 285 Gene3D G3DSA:3.40.1090.10 2 213 1.5E-31 T 28-03-2018 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 Pfam PF00303 Thymidylate synthase 6 266 4.2E-119 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 266 1.9E-89 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 6 88 2.3E-38 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 Gene3D G3DSA:3.30.572.10 4 266 4.1E-124 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 SUPERFAMILY SSF55831 6 266 2.22E-121 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 PRINTS PR00108 Thymidylate synthase family signature 118 137 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 PRINTS PR00108 Thymidylate synthase family signature 200 217 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 PRINTS PR00108 Thymidylate synthase family signature 144 159 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 PRINTS PR00108 Thymidylate synthase family signature 162 188 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 PRINTS PR00108 Thymidylate synthase family signature 45 66 3.9E-48 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS15140 e6668027a7fb9f77d3618cb085469553 266 Hamap MF_00008 Thymidylate synthase [thyA]. 4 266 38.376 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 Pfam PF00106 short chain dehydrogenase 7 201 5.3E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 Gene3D G3DSA:3.40.50.720 187 244 0.04 T 28-03-2018 CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 0.0018 T 28-03-2018 CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 SUPERFAMILY SSF51735 3 257 2.47E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS06820 9ee32c86c7f266083a44e184a9c965ca 276 Gene3D G3DSA:3.40.50.720 2 186 9.7E-53 T 28-03-2018 CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 Gene3D G3DSA:1.10.357.10 3 200 7.8E-33 T 28-03-2018 CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 SUPERFAMILY SSF48498 88 200 4.08E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 SUPERFAMILY SSF46689 5 84 1.44E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00430 4b6a4c2e378749c71ebefed00bab8a59 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 4.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS08665 e2a355d2389381d216b2960c74eef708 132 Pfam PF10888 Protein of unknown function (DUF2742) 35 130 1.6E-48 T 28-03-2018 IPR024384 Protein of unknown function DUF2742 CP478_RS08665 e2a355d2389381d216b2960c74eef708 132 ProDom PD032234 PHAGE PHIRV1 RV1583C/MT3573.2 PROBABLE RV2656C/MT2733 1 131 7.0E-68 T 28-03-2018 IPR024384 Protein of unknown function DUF2742 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 393 408 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 261 279 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 141 158 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 106 126 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 304 320 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 73 89 5.9E-51 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 Gene3D G3DSA:3.40.630.10 177 429 3.0E-74 T 28-03-2018 CP478_RS04345 106d6891c881599008282225d7c0a762 433 Gene3D G3DSA:3.40.630.10 1 127 3.3E-31 T 28-03-2018 CP478_RS04345 106d6891c881599008282225d7c0a762 433 SUPERFAMILY SSF53187 204 426 1.63E-89 T 28-03-2018 CP478_RS04345 106d6891c881599008282225d7c0a762 433 SUPERFAMILY SSF53187 4 84 1.63E-89 T 28-03-2018 CP478_RS04345 106d6891c881599008282225d7c0a762 433 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 11 425 7.8E-144 T 28-03-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CP478_RS04345 106d6891c881599008282225d7c0a762 433 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 428 59.084 T 28-03-2018 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 CP478_RS04345 106d6891c881599008282225d7c0a762 433 SUPERFAMILY SSF101821 85 203 2.2E-26 T 28-03-2018 CP478_RS20950 44bd479edd90d8c577da11f34ba20d14 137 SUPERFAMILY SSF55486 3 115 8.1E-36 T 28-03-2018 CP478_RS20950 44bd479edd90d8c577da11f34ba20d14 137 Pfam PF06262 Zincin-like metallopeptidase 29 115 5.8E-30 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CP478_RS16925 6dde6e97a14a143d0f46d8a142d758ad 334 Gene3D G3DSA:3.20.20.30 2 318 6.8E-47 T 28-03-2018 CP478_RS16925 6dde6e97a14a143d0f46d8a142d758ad 334 Pfam PF00296 Luciferase-like monooxygenase 17 297 1.0E-38 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16925 6dde6e97a14a143d0f46d8a142d758ad 334 SUPERFAMILY SSF51679 11 306 4.71E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16925 6dde6e97a14a143d0f46d8a142d758ad 334 TIGRFAM TIGR03841 F420_Rv3093c: probable F420-dependent oxidoreductase, Rv3093c family 8 304 2.5E-130 T 28-03-2018 IPR022526 F420-dependent oxidoreductase, Rv3093c CP478_RS09400 67a11c6778f24f4a4ea7ec640fbf65b6 415 SUPERFAMILY SSF56601 9 384 1.35E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS09400 67a11c6778f24f4a4ea7ec640fbf65b6 415 Pfam PF00144 Beta-lactamase 70 387 5.7E-42 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS09400 67a11c6778f24f4a4ea7ec640fbf65b6 415 Gene3D G3DSA:3.40.710.10 66 399 3.5E-37 T 28-03-2018 CP478_RS03640 5e83493f63e587b1d5d62378a309e34e 312 SUPERFAMILY SSF52096 10 283 9.1E-52 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS03640 5e83493f63e587b1d5d62378a309e34e 312 Gene3D G3DSA:3.90.226.10 8 312 1.6E-58 T 28-03-2018 CP478_RS03640 5e83493f63e587b1d5d62378a309e34e 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 124 270 3.8E-18 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS03640 5e83493f63e587b1d5d62378a309e34e 312 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 85 3.7E-10 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS16555 cccd74155cbbfd61b72c865b6b8a0314 304 SMART SM00563 95 226 6.7E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS16555 cccd74155cbbfd61b72c865b6b8a0314 304 SUPERFAMILY SSF69593 35 237 6.28E-20 T 28-03-2018 CP478_RS16555 cccd74155cbbfd61b72c865b6b8a0314 304 Pfam PF01553 Acyltransferase 81 222 1.9E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS16555 cccd74155cbbfd61b72c865b6b8a0314 304 Gene3D G3DSA:3.40.1130.10 62 259 4.1E-19 T 28-03-2018 CP478_RS06815 d15c4df6d9c17cc6f2c9a1f29d760eec 286 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 281 6.2E-29 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CP478_RS06815 d15c4df6d9c17cc6f2c9a1f29d760eec 286 Gene3D G3DSA:3.40.190.10 166 286 3.3E-9 T 28-03-2018 CP478_RS06815 d15c4df6d9c17cc6f2c9a1f29d760eec 286 SUPERFAMILY SSF53850 33 284 7.06E-26 T 28-03-2018 CP478_RS06815 d15c4df6d9c17cc6f2c9a1f29d760eec 286 Gene3D G3DSA:3.40.190.10 21 164 9.1E-16 T 28-03-2018 CP478_RS06825 0d667e4572ab701d1eee5cddabb7f5bd 97 Gene3D G3DSA:3.30.2310.20 1 91 1.8E-19 T 28-03-2018 CP478_RS06825 0d667e4572ab701d1eee5cddabb7f5bd 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 88 5.3E-10 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CP478_RS06825 0d667e4572ab701d1eee5cddabb7f5bd 97 SUPERFAMILY SSF143011 7 86 1.57E-17 T 28-03-2018 IPR035095 Toxin RelE-like domain CP478_RS11195 ed28a25ed21684d79b397e53d0112c12 175 Pfam PF04186 FxsA cytoplasmic membrane protein 4 109 2.4E-17 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CP478_RS17575 3486399815504874ee4ae58a8559200c 392 Pfam PF00899 ThiF family 23 258 1.0E-57 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS17575 3486399815504874ee4ae58a8559200c 392 SMART SM00450 290 387 2.1E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17575 3486399815504874ee4ae58a8559200c 392 Gene3D G3DSA:3.40.250.10 267 389 6.3E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17575 3486399815504874ee4ae58a8559200c 392 SUPERFAMILY SSF69572 10 359 4.71E-93 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS17575 3486399815504874ee4ae58a8559200c 392 Gene3D G3DSA:3.40.50.720 12 262 2.0E-65 T 28-03-2018 CP478_RS17575 3486399815504874ee4ae58a8559200c 392 Pfam PF00581 Rhodanese-like domain 290 383 2.1E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 SUPERFAMILY SSF103473 3 419 2.75E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 Gene3D G3DSA:1.20.1250.20 1 217 7.5E-22 T 28-03-2018 CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 11 408 2.8E-140 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 Pfam PF00083 Sugar (and other) transporter 5 422 5.3E-31 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CP478_RS06580 bf0fa988f2e5f0955cafa390bbb39522 425 Gene3D G3DSA:1.20.1250.20 218 424 1.6E-22 T 28-03-2018 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Gene3D G3DSA:3.30.1310.20 69 118 1.5E-22 T 28-03-2018 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 PIRSF PIRSF036794 233 668 6.1E-147 T 28-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 SUPERFAMILY SSF53271 17 223 3.27E-49 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Gene3D G3DSA:3.40.1660.10 429 661 1.4E-48 T 28-03-2018 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Gene3D G3DSA:3.30.1870.10 296 378 5.8E-28 T 28-03-2018 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Pfam PF00156 Phosphoribosyl transferase domain 23 202 7.2E-22 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Pfam PF05139 Erythromycin esterase 294 656 1.6E-109 T 28-03-2018 IPR007815 Erythromycin esterase GO:0046677 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 SUPERFAMILY SSF159501 248 662 3.92E-127 T 28-03-2018 CP478_RS11080 523a25abd1bff340ac7f1614eac8ece2 681 Gene3D G3DSA:3.40.50.2020 119 227 4.4E-21 T 28-03-2018 CP478_RS08460 7b808364363b16a821367f507cae344b 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS08460 7b808364363b16a821367f507cae344b 267 Gene3D G3DSA:3.40.50.720 3 257 1.7E-49 T 28-03-2018 CP478_RS08460 7b808364363b16a821367f507cae344b 267 SUPERFAMILY SSF51735 8 252 1.91E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PIRSF PIRSF000126 1 265 1.8E-71 T 28-03-2018 CP478_RS08460 7b808364363b16a821367f507cae344b 267 Pfam PF00106 short chain dehydrogenase 11 196 1.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 5.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS08460 7b808364363b16a821367f507cae344b 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 5.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 Gene3D G3DSA:1.10.150.240 49 119 6.9E-22 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 23 232 2.8E-64 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 133 232 1.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 Gene3D G3DSA:3.40.50.1000 18 48 0.22 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 Pfam PF13419 Haloacid dehalogenase-like hydrolase 26 230 2.0E-14 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 Gene3D G3DSA:3.40.50.1000 120 262 2.7E-22 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18610 aaee9b229ba9605d4350ea7ec54bf882 262 SUPERFAMILY SSF56784 22 261 1.36E-37 T 28-03-2018 IPR023214 HAD-like domain CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 254 424 4.3E-24 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 Gene3D G3DSA:1.20.120.450 249 373 9.9E-9 T 28-03-2018 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 SUPERFAMILY SSF109854 243 372 9.61E-10 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 Pfam PF01022 Bacterial regulatory protein, arsR family 8 52 7.9E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 SUPERFAMILY SSF46785 2 101 3.15E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 Gene3D G3DSA:3.30.530.20 104 248 6.6E-29 T 28-03-2018 IPR023393 START-like domain CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 115 228 8.7E-27 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 SMART SM00418 1 77 2.2E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 SUPERFAMILY SSF55961 102 241 9.55E-30 T 28-03-2018 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 255 424 2.8E-35 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 Gene3D G3DSA:1.10.10.10 1 98 1.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 5.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 2 17 5.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS03085 60a22c5e38ccaf76e2a3cfe0c415600f 434 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 5.4E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS07320 601c983b1ca71bf7a26cdb163b06302d 93 SUPERFAMILY SSF54285 1 93 1.41E-22 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CP478_RS07320 601c983b1ca71bf7a26cdb163b06302d 93 Pfam PF02597 ThiS family 5 93 2.4E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CP478_RS07320 601c983b1ca71bf7a26cdb163b06302d 93 Gene3D G3DSA:3.10.20.30 1 93 1.4E-22 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS03490 18cbed9f27eff1c9544c1b955e26235a 301 Pfam PF00561 alpha/beta hydrolase fold 26 148 6.0E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS03490 18cbed9f27eff1c9544c1b955e26235a 301 SUPERFAMILY SSF53474 6 294 6.76E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03490 18cbed9f27eff1c9544c1b955e26235a 301 Gene3D G3DSA:3.40.50.1820 3 301 4.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03440 aaa43129c7857209ad9098f9a027a1a7 166 PIRSF PIRSF018072 1 150 3.7E-53 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS03440 aaa43129c7857209ad9098f9a027a1a7 166 SUPERFAMILY SSF54637 15 153 3.37E-31 T 28-03-2018 IPR029069 HotDog domain CP478_RS03440 aaa43129c7857209ad9098f9a027a1a7 166 Hamap MF_00799 UPF0336 protein . 1 148 35.904 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CP478_RS03440 aaa43129c7857209ad9098f9a027a1a7 166 Pfam PF13452 N-terminal half of MaoC dehydratase 15 137 2.9E-25 T 28-03-2018 CP478_RS03440 aaa43129c7857209ad9098f9a027a1a7 166 Gene3D G3DSA:3.10.129.10 13 162 5.0E-26 T 28-03-2018 CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 257 1.5E-59 T 28-03-2018 CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 Gene3D G3DSA:3.40.50.720 2 258 3.7E-67 T 28-03-2018 CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 SUPERFAMILY SSF51735 17 258 4.74E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19450 feb9e0379cd9f35452f36a4acd145bd5 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS07635 74e0454946165af1b8498eedc2a6f4ad 492 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 205 7.7E-19 T 28-03-2018 CP478_RS07635 74e0454946165af1b8498eedc2a6f4ad 492 Gene3D G3DSA:3.50.50.60 4 161 2.3E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07635 74e0454946165af1b8498eedc2a6f4ad 492 Gene3D G3DSA:3.50.50.60 162 492 3.4E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07635 74e0454946165af1b8498eedc2a6f4ad 492 SUPERFAMILY SSF51905 5 226 1.55E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS07635 74e0454946165af1b8498eedc2a6f4ad 492 SUPERFAMILY SSF51905 295 407 1.55E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS13660 516cdf21425b4325d896dd8a94484245 273 PIRSF PIRSF015582 1 273 1.9E-72 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CP478_RS13660 516cdf21425b4325d896dd8a94484245 273 SUPERFAMILY SSF51621 9 223 2.58E-61 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS13660 516cdf21425b4325d896dd8a94484245 273 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 211 2.1E-28 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CP478_RS13660 516cdf21425b4325d896dd8a94484245 273 Gene3D G3DSA:3.20.20.60 2 223 1.2E-43 T 28-03-2018 CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Gene3D G3DSA:3.40.50.300 231 476 1.7E-43 T 28-03-2018 CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Gene3D G3DSA:3.40.50.300 9 230 2.1E-55 T 28-03-2018 CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Pfam PF00270 DEAD/DEAH box helicase 37 203 1.1E-48 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Pfam PF00271 Helicase conserved C-terminal domain 237 345 4.3E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 SMART SM00490 264 345 2.3E-33 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Pfam PF03880 DbpA RNA binding domain 471 538 1.7E-19 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 161 169 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 SMART SM00487 32 230 7.9E-60 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 8 543 43.785 T 28-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 CP478_RS06860 24b9d08f3aed0b87980705cb2ec82bec 563 SUPERFAMILY SSF52540 82 366 1.2E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01330 f777315f7fdf43c75c06cc616baddb4d 436 Gene3D G3DSA:1.20.1250.20 12 212 2.5E-5 T 28-03-2018 CP478_RS01330 f777315f7fdf43c75c06cc616baddb4d 436 SUPERFAMILY SSF103473 21 414 7.06E-18 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS01330 f777315f7fdf43c75c06cc616baddb4d 436 Gene3D G3DSA:1.20.1250.20 229 420 1.0E-5 T 28-03-2018 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 SUPERFAMILY SSF56655 10 281 2.23E-65 T 28-03-2018 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 234 248 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 Pfam PF00459 Inositol monophosphatase family 11 280 2.0E-62 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 101 114 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 Gene3D G3DSA:3.30.540.10 2 166 1.7E-39 T 28-03-2018 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 4.0E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 101 117 4.0E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 54 74 4.0E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 200 221 4.0E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 231 255 4.0E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CP478_RS14810 755fa614d78b6f42486c8227281a8276 290 Gene3D G3DSA:3.40.190.80 167 287 5.8E-34 T 28-03-2018 CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 Pfam PF09339 IclR helix-turn-helix domain 10 54 1.5E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 SUPERFAMILY SSF55781 62 233 2.16E-34 T 28-03-2018 IPR029016 GAF domain-like CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 Gene3D G3DSA:3.30.450.40 72 233 1.1E-32 T 28-03-2018 IPR029016 GAF domain-like CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 SMART SM00346 7 92 2.5E-27 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 6.7E-14 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 Gene3D G3DSA:1.10.10.10 1 71 1.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16340 0624a86b1e50dc097274191f185cbec4 233 SUPERFAMILY SSF46785 8 75 6.22E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17665 81038bb04c92c0c6127a414977ff9f30 101 Pfam PF13490 Putative zinc-finger 23 56 6.5E-10 T 28-03-2018 IPR027383 Putative zinc-finger CP478_RS17665 81038bb04c92c0c6127a414977ff9f30 101 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 23 97 1.4E-30 T 28-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA CP478_RS17665 81038bb04c92c0c6127a414977ff9f30 101 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 15 97 5.4E-32 T 28-03-2018 IPR014295 Anti-sigma factor CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 SMART SM00460 210 286 2.6E-23 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 314 1133 0.0 T 28-03-2018 IPR018667 Domain of unknown function DUF2126 CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 Gene3D G3DSA:3.90.260.10 204 346 1.2E-5 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 SUPERFAMILY SSF54001 35 375 6.59E-66 T 28-03-2018 CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 33 109 6.9E-24 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CP478_RS14070 6c71dd0d1964e8ead1466ffded9fd1c0 1140 Pfam PF01841 Transglutaminase-like superfamily 167 284 4.2E-18 T 28-03-2018 IPR002931 Transglutaminase-like CP478_RS01285 b1b516412773793586f55f503958ffec 388 SUPERFAMILY SSF51445 113 380 1.26E-59 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS01285 b1b516412773793586f55f503958ffec 388 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 62 378 1.6E-83 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS01285 b1b516412773793586f55f503958ffec 388 Gene3D G3DSA:3.20.20.300 53 381 1.1E-58 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CP478_RS04675 20c032457a6b37b6bdefa13765415089 134 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 2 115 1.6E-8 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CP478_RS04675 20c032457a6b37b6bdefa13765415089 134 Gene3D G3DSA:3.30.530.20 1 125 4.1E-12 T 28-03-2018 IPR023393 START-like domain CP478_RS04675 20c032457a6b37b6bdefa13765415089 134 SUPERFAMILY SSF55961 2 125 1.04E-15 T 28-03-2018 CP478_RS14315 eb33a34e07067ade76dcd759b142d211 195 Pfam PF01230 HIT domain 71 159 8.1E-15 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CP478_RS14315 eb33a34e07067ade76dcd759b142d211 195 Gene3D G3DSA:3.30.428.10 14 195 1.5E-41 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS14315 eb33a34e07067ade76dcd759b142d211 195 SUPERFAMILY SSF54197 60 192 2.32E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 Pfam PF00005 ABC transporter 342 485 1.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 SUPERFAMILY SSF52540 317 530 7.76E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 Gene3D G3DSA:1.20.1560.10 1 312 5.1E-26 T 28-03-2018 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 2 528 3.8E-152 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 ProSitePatterns PS00211 ABC transporters family signature. 457 471 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 SMART SM00382 348 531 1.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 Pfam PF00664 ABC transporter transmembrane region 18 264 1.5E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 Gene3D G3DSA:3.40.50.300 324 533 5.1E-57 T 28-03-2018 CP478_RS08865 5cb6c4578755018358339cb63509aec3 535 SUPERFAMILY SSF90123 2 308 2.75E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 Pfam PF00934 PE family 1 91 3.7E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 PRINTS PR01228 Eggshell protein signature 184 195 1.5E-5 T 28-03-2018 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 PRINTS PR01228 Eggshell protein signature 271 286 1.5E-5 T 28-03-2018 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 PRINTS PR01228 Eggshell protein signature 334 352 1.5E-5 T 28-03-2018 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 PRINTS PR01228 Eggshell protein signature 302 312 1.5E-5 T 28-03-2018 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 SUPERFAMILY SSF140459 8 83 4.45E-23 T 28-03-2018 CP478_RS03095 8b1dc4d93e503016f3356a59c65a0eb7 1303 Gene3D G3DSA:1.10.287.1060 1 96 0.0026 T 28-03-2018 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 Gene3D G3DSA:3.40.605.10 9 278 8.1E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 2.8E-159 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 SUPERFAMILY SSF53720 14 499 1.57E-158 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS02445 87b8aa6127d1b48e2b4c7295d49765ec 507 Gene3D G3DSA:3.40.309.10 279 481 1.7E-63 T 28-03-2018 CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 337 1.7E-88 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 Pfam PF01628 HrcA protein C terminal domain 105 326 4.0E-60 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 Gene3D G3DSA:3.30.450.40 172 343 5.0E-33 T 28-03-2018 IPR029016 GAF domain-like CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 Gene3D G3DSA:1.10.10.10 1 86 8.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 333 27.733 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 PIRSF PIRSF005485 1 343 1.1E-105 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 SUPERFAMILY SSF46785 5 85 3.53E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12945 15efcaaeb05ee90dae83d3a8bab472b6 343 SUPERFAMILY SSF55781 73 341 2.55E-53 T 28-03-2018 IPR029016 GAF domain-like CP478_RS20140 4d5e0364f0643f84c1f1f7bb5685125c 122 Pfam PF01740 STAS domain 10 111 2.8E-14 T 28-03-2018 IPR002645 STAS domain CP478_RS20140 4d5e0364f0643f84c1f1f7bb5685125c 122 SUPERFAMILY SSF52091 8 113 2.35E-18 T 28-03-2018 IPR002645 STAS domain CP478_RS20140 4d5e0364f0643f84c1f1f7bb5685125c 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 7 107 9.5E-17 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CP478_RS20140 4d5e0364f0643f84c1f1f7bb5685125c 122 Gene3D G3DSA:3.30.750.24 3 121 3.1E-19 T 28-03-2018 IPR002645 STAS domain CP478_RS04065 05e88655bf0ca8944da715967ec948c8 85 Gene3D G3DSA:1.10.1220.10 1 42 8.9E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS04065 05e88655bf0ca8944da715967ec948c8 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 36 1.3E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 SUPERFAMILY SSF53474 29 214 2.29E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 SMART SM01110 33 213 1.3E-91 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 Gene3D G3DSA:3.40.50.1820 30 217 5.5E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 Pfam PF01083 Cutinase 34 213 9.0E-62 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 ProSitePatterns PS00155 Cutinase, serine active site. 108 120 - T 28-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CP478_RS10800 f74fe12929589fcf0a3415f758e192fe 217 ProSitePatterns PS00931 Cutinase, aspartate and histidine active sites. 177 193 - T 28-03-2018 IPR011150 Cutinase, monofunctional GO:0005576|GO:0050525 CP478_RS20100 33a08959bb116fb73288e3f1bc87865c 118 Pfam PF02467 Transcription factor WhiB 31 93 2.4E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS20100 33a08959bb116fb73288e3f1bc87865c 118 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 29 98 17.004 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS03370 d153606a4adfa2e060d46312c7644507 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 8 131 14.774 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03370 d153606a4adfa2e060d46312c7644507 135 Pfam PF01850 PIN domain 9 125 7.6E-16 T 28-03-2018 IPR002716 PIN domain CP478_RS03370 d153606a4adfa2e060d46312c7644507 135 Gene3D G3DSA:3.40.50.1010 5 135 4.7E-21 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03370 d153606a4adfa2e060d46312c7644507 135 SUPERFAMILY SSF88723 9 126 1.79E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS11925 34779b26f2741c5292130d41166fe290 203 Gene3D G3DSA:1.20.120.80 19 203 5.4E-55 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS11925 34779b26f2741c5292130d41166fe290 203 Pfam PF00510 Cytochrome c oxidase subunit III 22 201 1.2E-26 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS11925 34779b26f2741c5292130d41166fe290 203 SUPERFAMILY SSF81452 12 201 9.03E-55 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS01685 42ff0b584c48cd2f6d2f09ec52b0d628 294 SUPERFAMILY SSF49899 45 293 1.12E-44 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CP478_RS01685 42ff0b584c48cd2f6d2f09ec52b0d628 294 Gene3D G3DSA:2.60.120.200 52 294 2.8E-43 T 28-03-2018 CP478_RS01685 42ff0b584c48cd2f6d2f09ec52b0d628 294 Pfam PF00722 Glycosyl hydrolases family 16 105 227 1.1E-13 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CP478_RS11515 6ceddcb30540113d2f35c49716d1b1b1 189 ProDom PD033474 ANTIGEN PRECURSOR SIGNAL LIPOPROTEIN LOW WEIGHT MOLECULAR LPPK MEMBRANE PALMITATE 45 164 2.0E-64 T 28-03-2018 IPR020235 Low molecular weight antigen MTB12 CP478_RS14220 543e2f1a54a5644366cd76e71672523c 81 SUPERFAMILY SSF89447 2 43 6.93E-10 T 28-03-2018 CP478_RS14220 543e2f1a54a5644366cd76e71672523c 81 Gene3D G3DSA:2.10.260.10 3 46 4.3E-12 T 28-03-2018 CP478_RS14220 543e2f1a54a5644366cd76e71672523c 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 44 7.0E-17 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CP478_RS14220 543e2f1a54a5644366cd76e71672523c 81 SMART SM00966 3 48 3.1E-9 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Gene3D G3DSA:3.40.50.980 210 361 5.1E-34 T 28-03-2018 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Gene3D G3DSA:2.30.38.10 363 455 1.3E-4 T 28-03-2018 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 549 8.2E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 SUPERFAMILY SSF56801 47 562 1.06E-101 T 28-03-2018 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Pfam PF00501 AMP-binding enzyme 53 464 3.8E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Gene3D G3DSA:3.40.50.980 44 209 6.5E-40 T 28-03-2018 CP478_RS06610 eddfe56466223682618ee1707f7b800f 597 Gene3D G3DSA:3.30.300.30 459 562 2.7E-14 T 28-03-2018 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 SUPERFAMILY SSF54373 294 396 2.94E-23 T 28-03-2018 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 Gene3D G3DSA:3.40.50.720 5 123 1.9E-15 T 28-03-2018 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 Pfam PF01593 Flavin containing amine oxidoreductase 13 443 4.2E-31 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 Gene3D G3DSA:3.90.660.20 197 396 2.9E-33 T 28-03-2018 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 7 443 6.5E-42 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 Gene3D G3DSA:1.10.3110.10 124 196 2.5E-17 T 28-03-2018 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 SUPERFAMILY SSF51905 408 445 1.23E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS14680 e7896c27e7d230a09f1366e09b84c8cb 452 SUPERFAMILY SSF51905 1 307 1.23E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16215 939739c0fa64b26273e136669caab69c 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 183 1.3E-61 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CP478_RS16215 939739c0fa64b26273e136669caab69c 188 Gene3D G3DSA:3.40.50.150 1 188 8.4E-34 T 28-03-2018 CP478_RS16215 939739c0fa64b26273e136669caab69c 188 SUPERFAMILY SSF53335 2 179 5.96E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16215 939739c0fa64b26273e136669caab69c 188 Pfam PF03602 Conserved hypothetical protein 95 2 180 2.3E-47 T 28-03-2018 CP478_RS16215 939739c0fa64b26273e136669caab69c 188 PIRSF PIRSF004553 1 185 9.5E-67 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CP478_RS16215 939739c0fa64b26273e136669caab69c 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CP478_RS20985 72c9e8dcab860cc5f536a3dad7f921da 274 Gene3D G3DSA:3.20.20.190 2 274 7.6E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS20985 72c9e8dcab860cc5f536a3dad7f921da 274 SUPERFAMILY SSF51695 11 264 3.14E-58 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS20985 72c9e8dcab860cc5f536a3dad7f921da 274 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 258 3.0E-50 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 Gene3D G3DSA:3.40.1050.10 1 206 4.1E-60 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 SUPERFAMILY SSF53056 3 198 1.44E-54 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 51 58 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 Pfam PF00484 Carbonic anhydrase 46 193 7.8E-39 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 SMART SM00947 39 198 2.3E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS19605 957fcd057a471e42eb5470f393c4c29b 207 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 88 108 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 SMART SM00382 32 219 2.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 SUPERFAMILY SSF52540 4 219 3.38E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 278 295 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 SMART SM00100 197 328 3.0E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 Pfam PF00005 ABC transporter 24 172 2.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 Pfam PF00027 Cyclic nucleotide-binding domain 229 311 1.3E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 Gene3D G3DSA:3.40.50.300 2 238 3.9E-60 T 28-03-2018 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 SUPERFAMILY SSF51206 228 313 1.44E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 Gene3D G3DSA:2.60.120.10 239 314 7.0E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 PRINTS PR00103 cAMP-dependent protein kinase signature 276 285 5.2E-9 T 28-03-2018 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 PRINTS PR00103 cAMP-dependent protein kinase signature 246 260 5.2E-9 T 28-03-2018 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 PRINTS PR00103 cAMP-dependent protein kinase signature 288 299 5.2E-9 T 28-03-2018 CP478_RS00405 1fc57d97ebecd97faaba7a958e583473 330 PRINTS PR00103 cAMP-dependent protein kinase signature 231 245 5.2E-9 T 28-03-2018 CP478_RS09860 1006c42ca52c766f9a8abc913b2addd0 234 Pfam PF02308 MgtC family 13 132 3.8E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CP478_RS09860 1006c42ca52c766f9a8abc913b2addd0 234 PRINTS PR01837 MgtC/SapB protein signature 35 53 5.0E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CP478_RS09860 1006c42ca52c766f9a8abc913b2addd0 234 PRINTS PR01837 MgtC/SapB protein signature 87 111 5.0E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CP478_RS09860 1006c42ca52c766f9a8abc913b2addd0 234 PRINTS PR01837 MgtC/SapB protein signature 16 35 5.0E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CP478_RS09860 1006c42ca52c766f9a8abc913b2addd0 234 PRINTS PR01837 MgtC/SapB protein signature 60 82 5.0E-41 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 SUPERFAMILY SSF53474 420 663 1.14E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 Gene3D G3DSA:3.40.50.1820 11 675 4.2E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 522 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 533 553 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 499 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 448 466 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 603 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 607 629 4.6E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 SUPERFAMILY SSF50993 13 414 1.7E-49 T 28-03-2018 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 13 394 1.5E-23 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CP478_RS02440 081a0e5a4ab63a9bf62fb4c39260fa48 676 Pfam PF00326 Prolyl oligopeptidase family 473 674 3.4E-47 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CP478_RS16810 c2a1eeb8b56cb363e14ab26a04b4356f 174 Gene3D G3DSA:3.20.20.30 7 157 3.4E-26 T 28-03-2018 CP478_RS16810 c2a1eeb8b56cb363e14ab26a04b4356f 174 SUPERFAMILY SSF51679 13 134 1.85E-24 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16810 c2a1eeb8b56cb363e14ab26a04b4356f 174 Pfam PF00296 Luciferase-like monooxygenase 18 133 1.1E-17 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS04630 8a7857441e73d51c89d1e4af43467008 372 Gene3D G3DSA:3.40.50.1100 163 329 1.3E-32 T 28-03-2018 CP478_RS04630 8a7857441e73d51c89d1e4af43467008 372 SUPERFAMILY SSF53686 30 333 8.25E-65 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS04630 8a7857441e73d51c89d1e4af43467008 372 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 314 1.9E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS04630 8a7857441e73d51c89d1e4af43467008 372 Gene3D G3DSA:3.40.50.1100 62 162 4.6E-19 T 28-03-2018 CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 SUPERFAMILY SSF56784 50 112 1.1E-6 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 Pfam PF02358 Trehalose-phosphatase 145 369 2.1E-72 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 139 380 5.3E-96 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 144 345 2.6E-17 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 SUPERFAMILY SSF56784 143 380 4.0E-43 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 Gene3D G3DSA:3.40.50.1000 50 114 8.1E-4 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18465 7351f56c7c5741eafa791b691aad625e 391 Gene3D G3DSA:3.40.50.1000 141 389 1.2E-22 T 28-03-2018 IPR023214 HAD-like domain CP478_RS18080 df83590ebffffb6a12967c0a3671b257 305 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18080 df83590ebffffb6a12967c0a3671b257 305 Pfam PF00849 RNA pseudouridylate synthase 93 237 1.1E-18 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18080 df83590ebffffb6a12967c0a3671b257 305 SUPERFAMILY SSF55120 77 285 9.12E-49 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS18080 df83590ebffffb6a12967c0a3671b257 305 Gene3D G3DSA:3.30.2350.10 85 286 4.7E-46 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 Gene3D G3DSA:2.30.38.10 381 462 1.8E-20 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 Gene3D G3DSA:3.40.50.980 3 175 7.7E-32 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 SUPERFAMILY SSF56801 6 573 2.62E-98 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 Gene3D G3DSA:3.40.50.980 176 351 7.5E-23 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 Gene3D G3DSA:3.30.300.30 463 572 2.6E-15 T 28-03-2018 CP478_RS16010 442149ff24cd6b33b228279dc2d2fa55 583 Pfam PF00501 AMP-binding enzyme 12 469 1.8E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS17570 2fbacc8b50df7678b416b5b3d25639de 292 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 12 288 4.7E-144 T 28-03-2018 IPR013402 Conserved hypothetical protein CHP02569 CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 Gene3D G3DSA:3.40.50.970 1 180 5.2E-37 T 28-03-2018 CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 Gene3D G3DSA:3.40.50.970 309 515 2.2E-35 T 28-03-2018 CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 SUPERFAMILY SSF52518 332 512 6.79E-44 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 164 8.6E-34 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 SUPERFAMILY SSF52518 2 165 1.55E-37 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS19185 4db68d1b03b7a09c8c377eee92350c31 515 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 508 2.7E-29 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS04775 f8fc2c2ca0f6bad6daa2f36a18391672 162 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 1 162 2.0E-88 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CP478_RS04775 f8fc2c2ca0f6bad6daa2f36a18391672 162 Pfam PF10969 Protein of unknown function (DUF2771) 7 159 6.3E-51 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CP478_RS02345 f3c65ba3ef8c52954d21a111e8afcd58 142 SUPERFAMILY SSF50475 7 103 4.49E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS02345 f3c65ba3ef8c52954d21a111e8afcd58 142 ProDom PD086639 PYRIDOXAMINE 5'-PHOSPHATE MB0449C OXIDASE-RELATED RV0441C/MT0457 6 123 3.0E-61 T 28-03-2018 IPR020145 Uncharacterised protein family, MT0457 CP478_RS02345 f3c65ba3ef8c52954d21a111e8afcd58 142 Gene3D G3DSA:2.30.110.10 3 132 1.3E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS11090 9e2af16a0bb0cb4f235fc5f3326b7768 331 SUPERFAMILY SSF55469 116 325 9.42E-10 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS11090 9e2af16a0bb0cb4f235fc5f3326b7768 331 SUPERFAMILY SSF55469 3 78 1.16E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS11090 9e2af16a0bb0cb4f235fc5f3326b7768 331 Gene3D G3DSA:3.40.109.10 1 325 1.7E-37 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS01530 cafebfa68fd771fb084fd76365ebd9b6 538 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 35 522 2.4E-177 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS01530 cafebfa68fd771fb084fd76365ebd9b6 538 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 37 510 1.8E-165 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS17025 f896e5f9082671619ac558d669600e6c 170 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 155 7.1E-71 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS17025 f896e5f9082671619ac558d669600e6c 170 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 6 161 35.729 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS17025 f896e5f9082671619ac558d669600e6c 170 SUPERFAMILY SSF55040 15 158 4.58E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS17025 f896e5f9082671619ac558d669600e6c 170 Gene3D G3DSA:3.30.70.640 6 161 1.3E-63 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS17025 f896e5f9082671619ac558d669600e6c 170 Pfam PF01967 MoaC family 19 153 5.0E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS08570 3253004707c9ea6d8ac1fa32d00f79f6 729 Pfam PF01757 Acyltransferase family 32 373 2.3E-16 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CP478_RS18980 9777ecc71d80de3a7f63d43fd84dc215 364 Pfam PF01370 NAD dependent epimerase/dehydratase family 39 207 4.3E-27 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS18980 9777ecc71d80de3a7f63d43fd84dc215 364 Gene3D G3DSA:3.40.50.720 36 335 1.6E-39 T 28-03-2018 CP478_RS18980 9777ecc71d80de3a7f63d43fd84dc215 364 SUPERFAMILY SSF51735 35 329 9.01E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS13710 a38dc243d09e3a0ab676b1d7abab1492 445 Pfam PF11700 Vacuole effluxer Atg22 like 150 434 4.0E-26 T 28-03-2018 IPR024671 Autophagy-related protein 22-like CP478_RS13710 a38dc243d09e3a0ab676b1d7abab1492 445 Gene3D G3DSA:1.20.1250.20 239 436 1.8E-19 T 28-03-2018 CP478_RS13710 a38dc243d09e3a0ab676b1d7abab1492 445 Gene3D G3DSA:1.20.1250.20 10 230 6.1E-9 T 28-03-2018 CP478_RS13710 a38dc243d09e3a0ab676b1d7abab1492 445 SUPERFAMILY SSF103473 25 429 1.11E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS18635 4c65edba5765c7cadf9db36b62789f74 234 Pfam PF00551 Formyl transferase 56 151 2.9E-15 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS18635 4c65edba5765c7cadf9db36b62789f74 234 Gene3D G3DSA:3.40.50.170 7 176 8.7E-28 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS18635 4c65edba5765c7cadf9db36b62789f74 234 SUPERFAMILY SSF53328 53 169 4.32E-27 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 SUPERFAMILY SSF48264 41 431 1.31E-73 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 Pfam PF00067 Cytochrome P450 242 407 7.4E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 Gene3D G3DSA:1.10.630.10 9 432 2.3E-58 T 28-03-2018 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00385 P450 superfamily signature 376 385 4.7E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00385 P450 superfamily signature 385 396 4.7E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00385 P450 superfamily signature 274 291 4.7E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00385 P450 superfamily signature 309 320 4.7E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 169 185 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 326 353 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 354 369 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 376 385 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 385 396 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 123 134 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 229 251 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 186 201 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 PRINTS PR00359 B-class P450 signature 309 320 4.5E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09685 e474d1d6a5c6beed819497faa4198d2f 434 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 378 387 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 42 283 8.1E-90 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 SUPERFAMILY SSF55920 6 284 2.36E-88 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.5E-50 T 28-03-2018 IPR000994 Peptidase M24 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.14 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 Gene3D G3DSA:3.90.230.10 34 285 3.5E-87 T 28-03-2018 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 5.6E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 5.6E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 5.6E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS15640 94db6b08075dc6439d98deef7dc81c80 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 5.6E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 Pfam PF00067 Cytochrome P450 62 466 1.4E-65 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 SUPERFAMILY SSF48264 54 492 9.95E-100 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 Gene3D G3DSA:1.10.630.10 49 491 7.0E-101 T 28-03-2018 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 432 441 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 56 73 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 294 320 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 423 439 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 382 396 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 398 416 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 349 365 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS16735 3c64f6d7fd928548320a6eb700526f3a 492 PRINTS PR00465 E-class P450 group IV signature 439 457 5.0E-24 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS06890 763872c8fdaf9aa8888cb84d5525802d 299 Gene3D G3DSA:3.40.470.10 76 298 6.7E-57 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS06890 763872c8fdaf9aa8888cb84d5525802d 299 SMART SM00986 120 289 1.6E-32 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS06890 763872c8fdaf9aa8888cb84d5525802d 299 SMART SM00987 120 289 1.6E-32 T 28-03-2018 CP478_RS06890 763872c8fdaf9aa8888cb84d5525802d 299 Pfam PF03167 Uracil DNA glycosylase superfamily 120 291 3.7E-29 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS06890 763872c8fdaf9aa8888cb84d5525802d 299 SUPERFAMILY SSF52141 87 294 7.85E-44 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CP478_RS19090 ab662177311a90daf19bcf509344f985 500 SUPERFAMILY SSF53756 20 494 2.13E-139 T 28-03-2018 CP478_RS19090 ab662177311a90daf19bcf509344f985 500 Gene3D G3DSA:3.40.50.2000 18 284 2.8E-84 T 28-03-2018 CP478_RS19090 ab662177311a90daf19bcf509344f985 500 Gene3D G3DSA:3.40.50.2000 285 477 1.0E-41 T 28-03-2018 CP478_RS19090 ab662177311a90daf19bcf509344f985 500 Pfam PF00982 Glycosyltransferase family 20 21 491 2.7E-161 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CP478_RS13410 d6653c9c63d3f28cd489de795772be33 373 Gene3D G3DSA:3.40.50.970 30 114 6.0E-20 T 28-03-2018 CP478_RS13410 d6653c9c63d3f28cd489de795772be33 373 Gene3D G3DSA:3.40.50.970 115 264 3.7E-41 T 28-03-2018 CP478_RS13410 d6653c9c63d3f28cd489de795772be33 373 SUPERFAMILY SSF52518 41 372 3.04E-84 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS13410 d6653c9c63d3f28cd489de795772be33 373 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 88 235 2.6E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CP478_RS12320 54350f16f41191322113a11b761e90bf 409 Gene3D G3DSA:1.20.1250.20 16 212 1.6E-14 T 28-03-2018 CP478_RS12320 54350f16f41191322113a11b761e90bf 409 SUPERFAMILY SSF103473 22 403 7.59E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12320 54350f16f41191322113a11b761e90bf 409 Gene3D G3DSA:1.20.1250.20 230 409 7.2E-11 T 28-03-2018 CP478_RS12320 54350f16f41191322113a11b761e90bf 409 Pfam PF07690 Major Facilitator Superfamily 49 272 1.8E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS10765 3839e8096829ee6de3d182dc767a575a 282 SUPERFAMILY SSF53335 57 237 9.99E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10765 3839e8096829ee6de3d182dc767a575a 282 Gene3D G3DSA:3.40.50.150 5 246 7.2E-18 T 28-03-2018 CP478_RS10765 3839e8096829ee6de3d182dc767a575a 282 Pfam PF13649 Methyltransferase domain 82 174 2.8E-11 T 28-03-2018 CP478_RS15345 c875dc9a2ea8c76f4bdefdda411bceb7 91 Pfam PF08681 Protein of unknown function (DUF1778) 8 84 2.7E-25 T 28-03-2018 IPR014795 Vibrio phage ICP1, Orf50 CP478_RS15345 c875dc9a2ea8c76f4bdefdda411bceb7 91 SUPERFAMILY SSF47598 6 82 8.53E-19 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS15345 c875dc9a2ea8c76f4bdefdda411bceb7 91 Gene3D G3DSA:1.20.5.780 6 84 7.7E-24 T 28-03-2018 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 Pfam PF01341 Glycosyl hydrolases family 6 105 363 2.2E-69 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 Gene3D G3DSA:3.20.20.40 92 378 2.2E-93 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PIRSF PIRSF001100 1 380 2.6E-116 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 SUPERFAMILY SSF51989 85 379 6.93E-99 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 183 198 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 238 251 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 316 336 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 155 168 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 268 278 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 298 311 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 111 130 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS00340 12460f9bf69c70320e9c3b0708b57ca5 380 PRINTS PR00733 Glycosyl hydrolase family 6 signature 340 354 1.0E-39 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CP478_RS12660 81e1070e7d1a1e34d6b94f717dcbe16b 221 SUPERFAMILY SSF53383 9 215 6.89E-42 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS12660 81e1070e7d1a1e34d6b94f717dcbe16b 221 Gene3D G3DSA:3.90.1150.10 1 165 1.5E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS12660 81e1070e7d1a1e34d6b94f717dcbe16b 221 Pfam PF00202 Aminotransferase class-III 20 217 2.0E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CP478_RS02705 c6eccb1d8815753295e78b8339e45430 373 Pfam PF12710 haloacid dehalogenase-like hydrolase 124 310 3.1E-27 T 28-03-2018 CP478_RS02705 c6eccb1d8815753295e78b8339e45430 373 Gene3D G3DSA:3.40.50.1000 121 348 3.2E-20 T 28-03-2018 IPR023214 HAD-like domain CP478_RS02705 c6eccb1d8815753295e78b8339e45430 373 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 123 324 1.6E-56 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CP478_RS02705 c6eccb1d8815753295e78b8339e45430 373 SUPERFAMILY SSF56784 123 329 9.9E-29 T 28-03-2018 IPR023214 HAD-like domain CP478_RS02705 c6eccb1d8815753295e78b8339e45430 373 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 123 313 1.2E-15 T 28-03-2018 CP478_RS15435 f522f95df8ce18f7a21f61374cd0d31a 124 Pfam PF03750 Csm2 Type III-A 7 120 6.2E-20 T 28-03-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A CP478_RS15435 f522f95df8ce18f7a21f61374cd0d31a 124 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 27 120 2.0E-22 T 28-03-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A CP478_RS07880 0eba95ef65c17bb61c8995daa5a1981c 141 Gene3D G3DSA:3.10.450.50 3 134 4.0E-20 T 28-03-2018 CP478_RS07880 0eba95ef65c17bb61c8995daa5a1981c 141 Pfam PF12680 SnoaL-like domain 10 109 2.6E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS07880 0eba95ef65c17bb61c8995daa5a1981c 141 SUPERFAMILY SSF54427 8 122 2.93E-19 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 Gene3D G3DSA:3.30.2350.10 83 253 3.2E-39 T 28-03-2018 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 Pfam PF00849 RNA pseudouridylate synthase 76 211 9.8E-20 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 SUPERFAMILY SSF55120 62 252 1.3E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 SMART SM00363 14 74 4.0E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 116 130 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 Gene3D G3DSA:3.10.290.10 7 82 4.0E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 Pfam PF01479 S4 domain 15 56 3.0E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 SUPERFAMILY SSF55174 14 68 4.71E-13 T 28-03-2018 CP478_RS09335 47e8c657eda3c29d9b609e8521bed5f0 254 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 80 240 3.1E-44 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CP478_RS07530 9adebf57f2e7171b43c5e053c313bfb0 326 Gene3D G3DSA:3.40.50.300 10 307 1.2E-29 T 28-03-2018 CP478_RS07530 9adebf57f2e7171b43c5e053c313bfb0 326 Pfam PF00685 Sulfotransferase domain 30 305 4.4E-59 T 28-03-2018 IPR000863 Sulfotransferase domain GO:0008146 CP478_RS07530 9adebf57f2e7171b43c5e053c313bfb0 326 SUPERFAMILY SSF52540 22 304 2.86E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14240 5ffa733cecfebd0459cccb77baebda60 143 ProDom PD031728 MEMBRANE PROBABLE RV2599/MT2674 PRECURSOR TRANSMEMBRANE B1177_F3_123 SIGNAL 1 119 2.0E-53 T 28-03-2018 CP478_RS14240 5ffa733cecfebd0459cccb77baebda60 143 Pfam PF14042 Domain of unknown function (DUF4247) 19 135 1.8E-32 T 28-03-2018 IPR025341 Protein of unknown function DUF4247 CP478_RS15210 6837e4ee3cea42d1c5aa9a96f201bd3c 356 Pfam PF10118 Predicted metal-dependent hydrolase 79 336 8.5E-78 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CP478_RS15210 6837e4ee3cea42d1c5aa9a96f201bd3c 356 Gene3D G3DSA:1.20.1260.10 99 316 3.0E-7 T 28-03-2018 IPR012347 Ferritin-related CP478_RS09300 56057ff9ad4ad552057eb2732867e915 385 Pfam PF00823 PPE family 5 161 7.1E-64 T 28-03-2018 IPR000030 PPE family CP478_RS09300 56057ff9ad4ad552057eb2732867e915 385 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 299 381 1.3E-22 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09300 56057ff9ad4ad552057eb2732867e915 385 Gene3D G3DSA:1.10.287.1060 22 105 2.2E-4 T 28-03-2018 CP478_RS09300 56057ff9ad4ad552057eb2732867e915 385 SUPERFAMILY SSF140459 2 174 8.37E-65 T 28-03-2018 CP478_RS01660 952333f36955926e7168d767e3c278db 163 Gene3D G3DSA:3.10.450.50 6 147 1.0E-29 T 28-03-2018 CP478_RS01660 952333f36955926e7168d767e3c278db 163 Pfam PF13577 SnoaL-like domain 14 134 3.3E-28 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS01660 952333f36955926e7168d767e3c278db 163 SUPERFAMILY SSF54427 11 144 5.86E-35 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS12275 88a556253ecbd8acef8914e802d75a07 170 Pfam PF11343 Protein of unknown function (DUF3145) 14 167 1.6E-69 T 28-03-2018 IPR021491 Protein of unknown function DUF3145 CP478_RS03550 cfc76c854fdf0ff3b4397b3f66aed66c 238 Pfam PF02517 CAAX protease self-immunity 134 222 1.4E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 Gene3D G3DSA:3.10.20.30 4 79 2.0E-20 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 4 82 1.2E-24 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 Gene3D G3DSA:3.90.1170.40 80 221 2.8E-50 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 Pfam PF02597 ThiS family 6 82 9.9E-18 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 Pfam PF02391 MoaE protein 89 200 8.6E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 SUPERFAMILY SSF54285 1 80 2.62E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CP478_RS18205 3e482d3c03f804d1675cf12c90ee79c5 221 SUPERFAMILY SSF54690 85 220 1.16E-44 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CP478_RS02020 9228d69e5c591e7ce15df23023b55431 71 Gene3D G3DSA:3.30.1660.10 3 66 6.4E-24 T 28-03-2018 IPR025543 Dodecin-like CP478_RS02020 9228d69e5c591e7ce15df23023b55431 71 Pfam PF07311 Dodecin 3 65 1.3E-20 T 28-03-2018 IPR009923 Dodecin CP478_RS02020 9228d69e5c591e7ce15df23023b55431 71 SUPERFAMILY SSF89807 3 67 2.49E-21 T 28-03-2018 IPR009923 Dodecin CP478_RS04745 90f3e7f0c628067af2c2771cf9a3bd3d 129 PIRSF PIRSF028777 1 129 3.3E-51 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CP478_RS04745 90f3e7f0c628067af2c2771cf9a3bd3d 129 Pfam PF03733 Inner membrane component domain 4 54 7.1E-18 T 28-03-2018 IPR005185 Inner membrane component domain CP478_RS04745 90f3e7f0c628067af2c2771cf9a3bd3d 129 Pfam PF03733 Inner membrane component domain 68 118 2.0E-16 T 28-03-2018 IPR005185 Inner membrane component domain CP478_RS17750 afd03e81dde3d121710ee27bdbfdc41f 385 Gene3D G3DSA:1.20.91.10 229 316 1.2E-6 T 28-03-2018 CP478_RS17750 afd03e81dde3d121710ee27bdbfdc41f 385 Pfam PF00999 Sodium/hydrogen exchanger family 13 367 7.0E-40 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CP478_RS01980 9233eb3f25976e72bf57f55ef95e4cc5 197 SUPERFAMILY SSF53448 6 188 3.83E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01980 9233eb3f25976e72bf57f55ef95e4cc5 197 Gene3D G3DSA:3.90.550.10 1 195 7.5E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01980 9233eb3f25976e72bf57f55ef95e4cc5 197 Pfam PF12804 MobA-like NTP transferase domain 8 164 4.1E-31 T 28-03-2018 IPR025877 MobA-like NTP transferase CP478_RS08030 6760ac03f01894ee40742ae738a63faf 162 Pfam PF01592 NifU-like N terminal domain 9 131 1.9E-36 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CP478_RS08030 6760ac03f01894ee40742ae738a63faf 162 SUPERFAMILY SSF82649 4 145 3.4E-44 T 28-03-2018 CP478_RS08030 6760ac03f01894ee40742ae738a63faf 162 Gene3D G3DSA:3.90.1010.10 5 161 2.9E-47 T 28-03-2018 CP478_RS08030 6760ac03f01894ee40742ae738a63faf 162 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 5 143 4.2E-52 T 28-03-2018 CP478_RS10835 6e6aedfcda38e399aaa45eebb2beac73 186 Pfam PF08808 RES domain 25 148 6.7E-15 T 28-03-2018 IPR014914 RES domain CP478_RS10835 6e6aedfcda38e399aaa45eebb2beac73 186 SMART SM00953 35 173 1.5E-6 T 28-03-2018 IPR014914 RES domain CP478_RS12565 7649608d2e9fb95d44857a55ffc9213e 238 SUPERFAMILY SSF46689 166 230 8.96E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS12565 7649608d2e9fb95d44857a55ffc9213e 238 Pfam PF04255 Protein of unknown function (DUF433) 173 226 2.5E-12 T 28-03-2018 IPR007367 Protein of unknown function DUF433 CP478_RS12565 7649608d2e9fb95d44857a55ffc9213e 238 Gene3D G3DSA:1.10.10.60 5 100 0.022 T 28-03-2018 CP478_RS12565 7649608d2e9fb95d44857a55ffc9213e 238 Gene3D G3DSA:1.10.10.10 173 232 1.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12565 7649608d2e9fb95d44857a55ffc9213e 238 PIRSF PIRSF037738 1 232 3.7E-78 T 28-03-2018 IPR017277 Putative antitoxin VapB45-like CP478_RS01595 7e940a165a0a47a4bab2c521140d65be 465 Gene3D G3DSA:3.40.720.10 10 321 9.1E-57 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS01595 7e940a165a0a47a4bab2c521140d65be 465 SUPERFAMILY SSF53649 8 445 2.18E-85 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS01595 7e940a165a0a47a4bab2c521140d65be 465 Pfam PF00884 Sulfatase 12 286 7.3E-42 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CP478_RS01595 7e940a165a0a47a4bab2c521140d65be 465 ProSitePatterns PS00523 Sulfatases signature 1. 56 68 - T 28-03-2018 IPR024607 Sulfatase, conserved site CP478_RS01595 7e940a165a0a47a4bab2c521140d65be 465 Gene3D G3DSA:3.30.1120.10 322 435 4.4E-17 T 28-03-2018 CP478_RS13720 3a6d9bab63cb3ad0426c30ebff27528e 533 Pfam PF05872 Bacterial protein of unknown function (DUF853) 39 532 4.9E-213 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal CP478_RS13720 3a6d9bab63cb3ad0426c30ebff27528e 533 Gene3D G3DSA:3.40.50.300 50 388 2.1E-21 T 28-03-2018 CP478_RS13720 3a6d9bab63cb3ad0426c30ebff27528e 533 Gene3D G3DSA:3.40.50.720 389 522 0.025 T 28-03-2018 CP478_RS13720 3a6d9bab63cb3ad0426c30ebff27528e 533 SUPERFAMILY SSF52540 42 400 1.0E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18880 4317de4af9f1595b6c6e499b2ce04240 470 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 5 468 2.5E-154 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS18880 4317de4af9f1595b6c6e499b2ce04240 470 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 455 1.3E-144 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS08215 98cc9f7e34e6f48c829c23f515a1f5bd 70 SUPERFAMILY SSF89807 3 68 3.4E-23 T 28-03-2018 IPR009923 Dodecin CP478_RS08215 98cc9f7e34e6f48c829c23f515a1f5bd 70 Pfam PF07311 Dodecin 5 68 4.0E-27 T 28-03-2018 IPR009923 Dodecin CP478_RS08215 98cc9f7e34e6f48c829c23f515a1f5bd 70 Gene3D G3DSA:3.30.1660.10 4 68 6.7E-29 T 28-03-2018 IPR025543 Dodecin-like CP478_RS07505 09580575997aaa05be904f3073af0ca2 401 SUPERFAMILY SSF56601 7 366 3.93E-82 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS07505 09580575997aaa05be904f3073af0ca2 401 Gene3D G3DSA:3.40.710.10 6 388 3.4E-79 T 28-03-2018 CP478_RS07505 09580575997aaa05be904f3073af0ca2 401 Pfam PF00144 Beta-lactamase 19 365 3.4E-67 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS06075 4c1fe26c650db41322c79f6ffe63c7fb 415 Gene3D G3DSA:3.90.226.10 147 241 1.3E-7 T 28-03-2018 CP478_RS06075 4c1fe26c650db41322c79f6ffe63c7fb 415 Pfam PF13742 OB-fold nucleic acid binding domain 12 104 6.1E-13 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CP478_RS06075 4c1fe26c650db41322c79f6ffe63c7fb 415 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 409 24.869 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06075 4c1fe26c650db41322c79f6ffe63c7fb 415 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 12 406 1.7E-108 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CP478_RS06075 4c1fe26c650db41322c79f6ffe63c7fb 415 Pfam PF02601 Exonuclease VII, large subunit 128 336 1.4E-60 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CP478_RS09925 e70c801b4fde87c2f3f0540f8423af1b 307 Pfam PF05949 Bacterial protein of unknown function (DUF881) 150 303 1.6E-34 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CP478_RS03865 9083fb5805be66ee7be948b31a768cd1 313 Pfam PF14494 Domain of unknown function (DUF4436) 58 310 4.1E-105 T 28-03-2018 IPR027948 Protein of unknown function (DUF4436) CP478_RS10760 24daacac31ea11c92405de92dbf0fa87 348 Pfam PF01435 Peptidase family M48 67 263 1.0E-33 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CP478_RS10760 24daacac31ea11c92405de92dbf0fa87 348 Gene3D G3DSA:3.30.2010.10 60 151 1.7E-17 T 28-03-2018 CP478_RS19650 f9ef5ac3b2abbec8f18aab9fb7bec1c1 112 Pfam PF11774 Lsr2 1 111 1.2E-43 T 28-03-2018 IPR024412 Lsr2 CP478_RS19650 f9ef5ac3b2abbec8f18aab9fb7bec1c1 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 108 1.0E-41 T 28-03-2018 IPR024412 Lsr2 CP478_RS08305 0cca7c137b5136576f3eee40e6c1ce28 262 SUPERFAMILY SSF53448 5 199 2.45E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08305 0cca7c137b5136576f3eee40e6c1ce28 262 Gene3D G3DSA:3.90.550.10 2 262 3.8E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08305 0cca7c137b5136576f3eee40e6c1ce28 262 Pfam PF00535 Glycosyl transferase family 2 8 110 1.2E-14 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS19550 dca52a2d1246b7a0c118723422f61b39 288 SUPERFAMILY SSF56281 11 251 6.72E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS19550 dca52a2d1246b7a0c118723422f61b39 288 Gene3D G3DSA:3.60.15.10 2 277 2.2E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SUPERFAMILY SSF52540 330 403 1.13E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SUPERFAMILY SSF52540 37 214 1.13E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SUPERFAMILY SSF52540 243 294 1.13E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 Gene3D G3DSA:3.40.50.300 5 245 2.0E-35 T 28-03-2018 CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 Gene3D G3DSA:3.40.50.300 246 405 1.1E-25 T 28-03-2018 CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 Pfam PF08494 DEAD/H associated 659 851 1.7E-70 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SMART SM00382 40 386 0.0029 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 Pfam PF00271 Helicase conserved C-terminal domain 335 399 2.4E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 Pfam PF00270 DEAD/DEAH box helicase 28 212 7.2E-26 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SMART SM00487 23 244 4.8E-37 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS18060 2320f0c079bf3761b0d7803ae04e8d7a 1513 SMART SM00490 286 399 2.8E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS20210 d1acc9ed60ca1fe990743de06d6d4f93 233 Gene3D G3DSA:3.40.50.150 23 191 1.3E-25 T 28-03-2018 CP478_RS20210 d1acc9ed60ca1fe990743de06d6d4f93 233 SUPERFAMILY SSF53335 7 192 1.02E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20210 d1acc9ed60ca1fe990743de06d6d4f93 233 Pfam PF13649 Methyltransferase domain 46 144 5.0E-15 T 28-03-2018 CP478_RS16775 edef090bf3a217d8f0c0fbb3fbb8c898 202 SUPERFAMILY SSF46689 7 85 1.95E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS16775 edef090bf3a217d8f0c0fbb3fbb8c898 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS16775 edef090bf3a217d8f0c0fbb3fbb8c898 202 Gene3D G3DSA:1.10.357.10 1 185 2.9E-34 T 28-03-2018 CP478_RS16775 edef090bf3a217d8f0c0fbb3fbb8c898 202 SUPERFAMILY SSF48498 90 183 1.56E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS10055 25e2cdae2a336150fa3bff8b2ce0b1ca 104 SUPERFAMILY SSF51278 1 103 1.31E-36 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10055 25e2cdae2a336150fa3bff8b2ce0b1ca 104 Hamap MF_01954 Urease subunit beta [ureB]. 1 102 27.904 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10055 25e2cdae2a336150fa3bff8b2ce0b1ca 104 Gene3D G3DSA:2.10.150.10 1 102 4.4E-36 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10055 25e2cdae2a336150fa3bff8b2ce0b1ca 104 Pfam PF00699 Urease beta subunit 3 96 1.5E-35 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS10055 25e2cdae2a336150fa3bff8b2ce0b1ca 104 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 95 3.5E-30 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CP478_RS13255 550ad3ae8d7882a7031787bf8f3eaea3 77 Gene3D G3DSA:3.40.190.10 3 53 1.1E-5 T 28-03-2018 CP478_RS05895 865c1fe3cd1e2b45dd4f3f26aa8affe6 314 Gene3D G3DSA:3.40.50.1110 66 274 3.3E-20 T 28-03-2018 CP478_RS05895 865c1fe3cd1e2b45dd4f3f26aa8affe6 314 SUPERFAMILY SSF52266 72 268 5.04E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS05895 865c1fe3cd1e2b45dd4f3f26aa8affe6 314 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 76 255 2.0E-14 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS14645 9d49dd819678ee40fa20faf3b8b860fc 258 SUPERFAMILY SSF53597 40 256 5.24E-39 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS14645 9d49dd819678ee40fa20faf3b8b860fc 258 Gene3D G3DSA:3.40.430.10 34 258 5.8E-40 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CP478_RS14645 9d49dd819678ee40fa20faf3b8b860fc 258 Pfam PF01872 RibD C-terminal domain 40 251 4.0E-48 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 SUPERFAMILY SSF89919 2 116 3.66E-25 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 17.712 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 Pfam PF02033 Ribosome-binding factor A 6 113 4.6E-22 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 1.4E-16 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 Gene3D G3DSA:3.30.300.20 4 120 4.6E-24 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CP478_RS15520 5d15ccddeb4dd4370f84e8a3113a1232 183 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 20 100 1.0E-36 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CP478_RS09870 ad956f5bd9bcce01d3ddbfd617bf166b 143 Pfam PF13827 Domain of unknown function (DUF4189) 58 142 2.3E-15 T 28-03-2018 IPR025240 Domain of unknown function DUF4189 CP478_RS09870 ad956f5bd9bcce01d3ddbfd617bf166b 143 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 57 143 1.0E-49 T 28-03-2018 CP478_RS08595 af891f64a855c13049fe8cd29a30db30 226 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 216 22.38 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CP478_RS08595 af891f64a855c13049fe8cd29a30db30 226 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 168 9.6E-28 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CP478_RS08595 af891f64a855c13049fe8cd29a30db30 226 SUPERFAMILY SSF52540 3 183 2.0E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08595 af891f64a855c13049fe8cd29a30db30 226 Gene3D G3DSA:3.40.50.300 2 202 4.5E-41 T 28-03-2018 CP478_RS08595 af891f64a855c13049fe8cd29a30db30 226 Pfam PF13500 AAA domain 4 191 3.4E-29 T 28-03-2018 CP478_RS08530 ebd48801afca57dde74a51538f074e2a 397 SUPERFAMILY SSF82866 147 356 1.02E-29 T 28-03-2018 CP478_RS08530 ebd48801afca57dde74a51538f074e2a 397 Pfam PF03176 MMPL family 29 364 4.9E-102 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS08530 ebd48801afca57dde74a51538f074e2a 397 Gene3D G3DSA:1.20.1640.10 143 353 5.1E-26 T 28-03-2018 CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 SUPERFAMILY SSF48498 80 202 8.9E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 Gene3D G3DSA:1.10.357.10 59 208 4.0E-22 T 28-03-2018 CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 Gene3D G3DSA:1.10.10.60 2 58 4.7E-15 T 28-03-2018 CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 Pfam PF13305 WHG domain 83 182 4.6E-12 T 28-03-2018 IPR025996 WHG domain CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS03525 123d30f51413a3e3c9e6c3cf56400d6f 231 SUPERFAMILY SSF46689 7 65 3.18E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS19025 7a1198913a3573c17d47818f274fc79a 393 Pfam PF00823 PPE family 6 162 1.6E-56 T 28-03-2018 IPR000030 PPE family CP478_RS19025 7a1198913a3573c17d47818f274fc79a 393 Gene3D G3DSA:1.10.287.1060 22 103 5.9E-4 T 28-03-2018 CP478_RS19025 7a1198913a3573c17d47818f274fc79a 393 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 309 388 3.5E-15 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS19025 7a1198913a3573c17d47818f274fc79a 393 SUPERFAMILY SSF140459 3 175 3.14E-58 T 28-03-2018 CP478_RS10425 85d322c4cecb7dc480c669a9175d31df 398 SUPERFAMILY SSF51621 12 215 1.57E-52 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS10425 85d322c4cecb7dc480c669a9175d31df 398 Gene3D G3DSA:3.20.20.60 32 215 2.4E-49 T 28-03-2018 CP478_RS10425 85d322c4cecb7dc480c669a9175d31df 398 Pfam PF00463 Isocitrate lyase family 33 231 1.2E-44 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS10425 85d322c4cecb7dc480c669a9175d31df 398 PIRSF PIRSF001362 32 236 2.6E-44 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CP478_RS15530 a1e6cc21061b22873a558e4bebc03a84 99 Pfam PF04296 Protein of unknown function (DUF448) 2 82 3.2E-20 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CP478_RS15530 a1e6cc21061b22873a558e4bebc03a84 99 SUPERFAMILY SSF64376 1 84 1.83E-19 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CP478_RS15530 a1e6cc21061b22873a558e4bebc03a84 99 Gene3D G3DSA:3.30.1230.10 1 87 5.5E-21 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CP478_RS09125 f315b702f26d325d53958369bcdd012e 115 Pfam PF04248 Domain of unknown function (DUF427) 2 91 2.7E-29 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CP478_RS21180 cc07ccd8b8e5b75855e6a2e9beae47b1 100 SUPERFAMILY SSF140453 3 99 5.49E-22 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21180 cc07ccd8b8e5b75855e6a2e9beae47b1 100 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 1.7E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21180 cc07ccd8b8e5b75855e6a2e9beae47b1 100 Gene3D G3DSA:1.10.287.1060 1 96 8.2E-17 T 28-03-2018 CP478_RS21180 cc07ccd8b8e5b75855e6a2e9beae47b1 100 Pfam PF06013 Proteins of 100 residues with WXG 4 88 2.7E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS13625 766a2903f1f08e492817f46543660902 207 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 27 195 6.0E-67 T 28-03-2018 IPR005268 Conserved hypothetical protein CHP00725 CP478_RS13625 766a2903f1f08e492817f46543660902 207 Gene3D G3DSA:3.40.50.450 14 174 2.3E-22 T 28-03-2018 CP478_RS13625 766a2903f1f08e492817f46543660902 207 SUPERFAMILY SSF102405 25 174 7.48E-29 T 28-03-2018 CP478_RS16890 ca9cb0d35ddc5c9b7c49addecd7a47c2 474 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 461 3.6E-136 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS16890 ca9cb0d35ddc5c9b7c49addecd7a47c2 474 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 273 5.0E-84 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS16890 ca9cb0d35ddc5c9b7c49addecd7a47c2 474 Pfam PF06974 Protein of unknown function (DUF1298) 313 457 1.7E-28 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS20945 489597499da47aa02a960f51e4d44832 449 Pfam PF13845 Septum formation 98 322 4.3E-78 T 28-03-2018 IPR026004 Septum formation-related domain CP478_RS13990 18265a50d497303d4524086217e69709 139 Pfam PF01478 Type IV leader peptidase family 6 108 6.9E-17 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 SUPERFAMILY SSF52540 460 672 1.19E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 794 1384 9.9E-163 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 716 4.7E-220 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 SUPERFAMILY SSF52540 809 1060 4.76E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 Gene3D G3DSA:3.40.50.300 395 680 6.9E-19 T 28-03-2018 CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 Gene3D G3DSA:3.40.50.300 1123 1337 4.0E-4 T 28-03-2018 CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 Gene3D G3DSA:3.40.50.300 788 1063 4.2E-10 T 28-03-2018 CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 SMART SM00382 491 669 0.3 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 SMART SM00382 868 1068 0.026 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 SMART SM00382 1170 1372 4.1 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 Pfam PF01580 FtsK/SpoIIIE family 463 672 2.4E-22 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS09715 55111f4aa1e4bc01e538aae80963968e 1391 Pfam PF01580 FtsK/SpoIIIE family 824 1096 4.2E-82 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 SMART SM00825 Beta-ketoacyl synthase 7 431 6.7E-135 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 254 1.9E-77 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 381 437 1.1E-7 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 Gene3D G3DSA:3.40.47.10 269 429 6.2E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 Gene3D G3DSA:3.40.47.10 1 266 2.0E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 SUPERFAMILY SSF53901 2 376 1.87E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS12985 9c310d48ef39beb48c74851e8200af6d 444 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 378 1.6E-35 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CP478_RS08805 6c21ac2f6e8c280e51a0eb64e91ae5a3 235 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 23 224 5.0E-45 T 28-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CP478_RS08805 6c21ac2f6e8c280e51a0eb64e91ae5a3 235 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 18 226 1.3E-58 T 28-03-2018 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein CP478_RS14780 a88d6664ad76ccbada8264080c396035 235 SUPERFAMILY SSF53474 7 209 7.34E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14780 a88d6664ad76ccbada8264080c396035 235 Pfam PF12697 Alpha/beta hydrolase family 11 196 9.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS14780 a88d6664ad76ccbada8264080c396035 235 Gene3D G3DSA:3.40.50.1820 5 232 4.8E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19385 74820b51f129fea12462b11d4d986284 151 Pfam PF04075 F420H(2)-dependent quinone reductase 22 151 2.3E-58 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS19385 74820b51f129fea12462b11d4d986284 151 Gene3D G3DSA:2.30.110.10 15 151 1.1E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS19385 74820b51f129fea12462b11d4d986284 151 SUPERFAMILY SSF50475 41 144 3.37E-10 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS19385 74820b51f129fea12462b11d4d986284 151 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 38 150 6.1E-43 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 Pfam PF00561 alpha/beta hydrolase fold 35 134 9.3E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 7.9E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 7.9E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 7.9E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 7.9E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00412 Epoxide hydrolase signature 228 244 4.1E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00412 Epoxide hydrolase signature 105 118 4.1E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00412 Epoxide hydrolase signature 41 59 4.1E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00412 Epoxide hydrolase signature 262 284 4.1E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 PRINTS PR00412 Epoxide hydrolase signature 119 132 4.1E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 Hamap MF_01230 Haloalkane dehalogenase [dhmA]. 1 286 47.747 T 28-03-2018 IPR023489 Haloalkane dehalogenase, subfamily 1 GO:0018786 KEGG: 00361+3.8.1.5|KEGG: 00625+3.8.1.5 CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 Gene3D G3DSA:3.40.50.1820 6 285 3.4E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS09970 b71c87f1559612beea4ee82195f375e2 286 SUPERFAMILY SSF53474 11 283 6.61E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00510 9aae6077c11c560f47d43f11e6ed3cc1 255 Pfam PF01048 Phosphorylase superfamily 5 249 4.3E-45 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS00510 9aae6077c11c560f47d43f11e6ed3cc1 255 Gene3D G3DSA:3.40.50.1580 1 254 3.5E-53 T 28-03-2018 CP478_RS00510 9aae6077c11c560f47d43f11e6ed3cc1 255 SUPERFAMILY SSF53167 4 252 2.36E-56 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 Pfam PF00891 O-methyltransferase 103 325 2.3E-43 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 Gene3D G3DSA:3.40.50.150 96 339 2.5E-42 T 28-03-2018 CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 Pfam PF16864 Dimerisation domain 8 92 6.5E-13 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 Gene3D G3DSA:1.10.10.10 2 95 5.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 PIRSF PIRSF005739 6 339 6.2E-34 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 SUPERFAMILY SSF53335 93 332 1.17E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS03035 2695193b80796ed8699470b13a92bf53 339 SUPERFAMILY SSF46785 7 89 1.28E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11940 7683e93327a766051cf8f98b0290b11d 549 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 120 294 1.9E-60 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CP478_RS11940 7683e93327a766051cf8f98b0290b11d 549 Gene3D G3DSA:1.20.810.10 21 441 4.6E-99 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CP478_RS11940 7683e93327a766051cf8f98b0290b11d 549 SUPERFAMILY SSF81342 21 299 2.04E-59 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CP478_RS15710 1c182c19d3705f30a8bd2a6a57389f67 63 SUPERFAMILY SSF143120 20 54 7.32E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS15710 1c182c19d3705f30a8bd2a6a57389f67 63 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 19 53 1.7E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS15710 1c182c19d3705f30a8bd2a6a57389f67 63 Gene3D G3DSA:3.40.1620.10 17 55 1.7E-11 T 28-03-2018 CP478_RS15710 1c182c19d3705f30a8bd2a6a57389f67 63 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 19 53 2.5E-11 T 28-03-2018 CP478_RS14795 5f8ed9a5fc6b49b5529918eea25fa209 161 Pfam PF11292 Protein of unknown function (DUF3093) 12 159 4.0E-51 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 CP478_RS03560 09ab422c2c9e63cd26ced6a29a70e613 81 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 37 1.0E-4 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS03560 09ab422c2c9e63cd26ced6a29a70e613 81 Gene3D G3DSA:1.10.1220.10 2 39 1.5E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SMART SM00487 14 196 1.5E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SMART SM00490 331 416 4.5E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 Gene3D G3DSA:3.40.50.300 3 190 6.8E-34 T 28-03-2018 CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 Pfam PF00271 Helicase conserved C-terminal domain 340 416 1.8E-5 T 28-03-2018 IPR001650 Helicase, C-terminal CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 Gene3D G3DSA:3.40.50.300 223 709 1.3E-16 T 28-03-2018 CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 Pfam PF00270 DEAD/DEAH box helicase 20 167 9.3E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 Pfam PF08148 DSHCT (NUC185) domain 729 901 1.1E-39 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SUPERFAMILY SSF52540 28 169 1.96E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SUPERFAMILY SSF52540 255 294 1.96E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SUPERFAMILY SSF52540 336 430 1.96E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS11395 aa28d2c7baae9994355f690bb841ddec 906 SMART SM01142 725 906 1.3E-64 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 Pfam PF01494 FAD binding domain 7 306 3.2E-15 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 SUPERFAMILY SSF51905 7 171 2.36E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 SUPERFAMILY SSF51905 278 343 2.36E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.1E-10 T 28-03-2018 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.1E-10 T 28-03-2018 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.1E-10 T 28-03-2018 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-10 T 28-03-2018 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 8 316 6.7E-71 T 28-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 Gene3D G3DSA:3.30.9.10 157 324 5.9E-44 T 28-03-2018 CP478_RS03000 dd2d9bf804e436e8c0c8863dfd14907d 408 Gene3D G3DSA:3.50.50.60 2 156 4.4E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03540 970a678ca5582f726bd0528fcbf57de3 127 Gene3D G3DSA:3.40.50.1010 2 123 1.9E-6 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03540 970a678ca5582f726bd0528fcbf57de3 127 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 118 11.946 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS18760 9a5342d5a040f2505ba2a11d51cc1963 410 SUPERFAMILY SSF53098 72 207 1.95E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS18760 9a5342d5a040f2505ba2a11d51cc1963 410 Gene3D G3DSA:3.30.420.10 50 225 1.8E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS18760 9a5342d5a040f2505ba2a11d51cc1963 410 Pfam PF00665 Integrase core domain 66 174 2.5E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 Pfam PF00082 Subtilase family 81 379 4.3E-33 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 Gene3D G3DSA:3.40.50.200 44 391 1.2E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 SUPERFAMILY SSF52743 64 388 1.96E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 PRINTS PR00723 Subtilisin serine protease family (S8) signature 329 345 4.2E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 PRINTS PR00723 Subtilisin serine protease family (S8) signature 81 100 4.2E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 PRINTS PR00723 Subtilisin serine protease family (S8) signature 117 130 4.2E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CP478_RS21225 9c6befb078b3c016b45c406d9383980c 446 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 71 439 3.4E-121 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CP478_RS01575 cb7dcb6b92ac8ec1a42ae8347f7ec7d3 331 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 127 214 9.7E-15 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS01575 cb7dcb6b92ac8ec1a42ae8347f7ec7d3 331 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 11 295 9.0E-73 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 Gene3D G3DSA:3.50.50.60 122 252 6.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 SUPERFAMILY SSF51905 2 101 9.18E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 SUPERFAMILY SSF51905 200 323 9.18E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-6 T 28-03-2018 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.0E-6 T 28-03-2018 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.0E-6 T 28-03-2018 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 SUPERFAMILY SSF51905 115 252 7.13E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 Gene3D G3DSA:3.40.50.720 1 121 2.7E-10 T 28-03-2018 CP478_RS01770 52e0881fd039ab823a8f3d361712c621 388 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 2.2E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 Pfam PF07969 Amidohydrolase family 60 215 1.1E-12 T 28-03-2018 IPR013108 Amidohydrolase 3 CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 Gene3D G3DSA:2.30.40.10 15 83 2.8E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 SUPERFAMILY SSF51556 72 334 2.07E-46 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 SUPERFAMILY SSF51556 383 514 2.07E-46 T 28-03-2018 IPR032466 Metal-dependent hydrolase CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 Gene3D G3DSA:3.20.20.140 84 513 1.4E-48 T 28-03-2018 CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 SUPERFAMILY SSF51338 517 586 2.47E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS15910 108655e6eb39a39b10ed64a3cc0fb0e7 611 SUPERFAMILY SSF51338 16 71 2.47E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 Gene3D G3DSA:3.40.50.720 8 267 7.9E-53 T 28-03-2018 CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 Pfam PF00106 short chain dehydrogenase 18 199 5.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 SUPERFAMILY SSF51735 15 259 9.93E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10135 8de3e96e00bdb08a8272c7bcebe453d7 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS10175 a2c820108120941bf9cb58cdbd8f5ba9 414 SUPERFAMILY SSF51395 35 401 2.38E-91 T 28-03-2018 CP478_RS10175 a2c820108120941bf9cb58cdbd8f5ba9 414 Pfam PF01070 FMN-dependent dehydrogenase 44 402 1.9E-123 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CP478_RS10175 a2c820108120941bf9cb58cdbd8f5ba9 414 PIRSF PIRSF000138 15 406 3.3E-124 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CP478_RS10175 a2c820108120941bf9cb58cdbd8f5ba9 414 Gene3D G3DSA:3.20.20.70 33 406 2.5E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS10175 a2c820108120941bf9cb58cdbd8f5ba9 414 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 299 305 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CP478_RS21285 89e558d59f957f22c758fdf3de22b738 495 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 467 7.3E-152 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS21285 89e558d59f957f22c758fdf3de22b738 495 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 5 479 1.6E-153 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS17520 098ced5f4ad2eadc7c1e724db8510c1e 92 Pfam PF02467 Transcription factor WhiB 20 68 3.2E-14 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS17520 098ced5f4ad2eadc7c1e724db8510c1e 92 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 18 82 15.3 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS17520 098ced5f4ad2eadc7c1e724db8510c1e 92 Pfam PF02178 AT hook motif 80 91 0.0036 T 28-03-2018 IPR017956 AT hook, DNA-binding motif GO:0003677 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 Gene3D G3DSA:3.40.50.1100 42 139 3.8E-37 T 28-03-2018 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 SUPERFAMILY SSF53686 2 306 2.88E-107 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 305 9.8E-137 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 Gene3D G3DSA:3.40.50.1100 140 308 8.9E-63 T 28-03-2018 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 305 1.6E-142 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CP478_RS12730 d9361ab10f7f64afe8feca1febb8bd13 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 294 2.0E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CP478_RS00935 eefe2daec2620fad50016dcc14459c3a 346 Pfam PF02470 MlaD protein 37 112 1.6E-18 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS00935 eefe2daec2620fad50016dcc14459c3a 346 Gene3D G3DSA:1.10.287.950 169 278 1.5E-6 T 28-03-2018 CP478_RS00935 eefe2daec2620fad50016dcc14459c3a 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 7.4E-88 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS12470 be96738953b5a9950486670d36f4f43b 212 Pfam PF03691 Uncharacterised protein family (UPF0167) 37 211 1.5E-60 T 28-03-2018 IPR005363 Uncharacterised protein family UPF0167 CP478_RS01480 ec5d32bd86ce6715d928f2a335b20c29 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 70 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS01480 ec5d32bd86ce6715d928f2a335b20c29 241 Gene3D G3DSA:1.10.357.10 5 234 1.7E-21 T 28-03-2018 CP478_RS01480 ec5d32bd86ce6715d928f2a335b20c29 241 SUPERFAMILY SSF46689 16 86 2.14E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00725 8934939315142fb8bbc26a8c6eab67dd 201 Pfam PF00583 Acetyltransferase (GNAT) family 116 178 1.6E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS00725 8934939315142fb8bbc26a8c6eab67dd 201 SUPERFAMILY SSF55729 6 198 3.37E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS00725 8934939315142fb8bbc26a8c6eab67dd 201 Gene3D G3DSA:3.40.630.30 1 201 5.4E-36 T 28-03-2018 CP478_RS06855 9f85958d4d683c49bf64dcefb9efe315 202 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 202 5.0E-93 T 28-03-2018 CP478_RS06855 9f85958d4d683c49bf64dcefb9efe315 202 Pfam PF14041 LppP/LprE lipoprotein 113 190 2.1E-13 T 28-03-2018 IPR025971 LppP/LprE lipoprotein CP478_RS15800 03c4aa125cd832d14cf317b0517a37a9 249 Pfam PF01551 Peptidase family M23 65 151 1.3E-11 T 28-03-2018 IPR016047 Peptidase M23 CP478_RS15800 03c4aa125cd832d14cf317b0517a37a9 249 Gene3D G3DSA:2.70.70.10 30 169 4.3E-20 T 28-03-2018 CP478_RS15800 03c4aa125cd832d14cf317b0517a37a9 249 SUPERFAMILY SSF51261 36 167 6.28E-14 T 28-03-2018 IPR011055 Duplicated hybrid motif CP478_RS14625 91998d5c165853bc06ea1888cb374759 252 Gene3D G3DSA:1.10.1780.10 88 236 8.1E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS14625 91998d5c165853bc06ea1888cb374759 252 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 110 157 1.2E-7 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS14625 91998d5c165853bc06ea1888cb374759 252 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 184 223 8.1E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS14625 91998d5c165853bc06ea1888cb374759 252 SUPERFAMILY SSF81923 98 227 8.73E-25 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CP478_RS07725 53acb77a33201731a75c1fcf7bc64939 236 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 45 230 2.0E-104 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS07725 53acb77a33201731a75c1fcf7bc64939 236 Pfam PF07161 LppX_LprAFG lipoprotein 40 230 2.2E-78 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CP478_RS07725 53acb77a33201731a75c1fcf7bc64939 236 SUPERFAMILY SSF89392 37 231 8.63E-59 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CP478_RS07725 53acb77a33201731a75c1fcf7bc64939 236 Gene3D G3DSA:3.40.190.10 4 231 2.6E-5 T 28-03-2018 CP478_RS21175 4cbed8eb4351cedef44e73e80a9bcbb0 368 SUPERFAMILY SSF140459 2 167 4.97E-53 T 28-03-2018 CP478_RS21175 4cbed8eb4351cedef44e73e80a9bcbb0 368 Pfam PF00823 PPE family 5 160 6.2E-51 T 28-03-2018 IPR000030 PPE family CP478_RS21175 4cbed8eb4351cedef44e73e80a9bcbb0 368 Gene3D G3DSA:1.10.287.850 19 106 6.5E-5 T 28-03-2018 CP478_RS05390 9f6ced0e998c65fed10ebb10bb5386be 855 Pfam PF12704 MacB-like periplasmic core domain 28 234 3.3E-12 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CP478_RS05390 9f6ced0e998c65fed10ebb10bb5386be 855 Pfam PF02687 FtsX-like permease family 755 847 4.5E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CP478_RS05390 9f6ced0e998c65fed10ebb10bb5386be 855 Pfam PF02687 FtsX-like permease family 290 386 2.4E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CP478_RS18750 c8fcc9efd62b393beab10f675da6e8fa 232 Gene3D G3DSA:1.10.287.1060 19 100 2.3E-7 T 28-03-2018 CP478_RS18750 c8fcc9efd62b393beab10f675da6e8fa 232 Pfam PF00823 PPE family 4 167 3.5E-45 T 28-03-2018 IPR000030 PPE family CP478_RS18750 c8fcc9efd62b393beab10f675da6e8fa 232 SUPERFAMILY SSF140459 2 126 3.14E-35 T 28-03-2018 CP478_RS15700 469660e68d539285688a0f3b3aa47655 147 Gene3D G3DSA:3.40.50.1010 2 141 1.2E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15700 469660e68d539285688a0f3b3aa47655 147 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 17.684 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS15700 469660e68d539285688a0f3b3aa47655 147 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 142 6.5E-53 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS15700 469660e68d539285688a0f3b3aa47655 147 SUPERFAMILY SSF88723 1 140 4.21E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15700 469660e68d539285688a0f3b3aa47655 147 Pfam PF01850 PIN domain 3 133 5.9E-13 T 28-03-2018 IPR002716 PIN domain CP478_RS10750 adf56344ee4f40a6a9c6eb86adcc4ee8 221 SUPERFAMILY SSF55797 49 159 1.94E-5 T 28-03-2018 IPR014044 CAP domain CP478_RS10750 adf56344ee4f40a6a9c6eb86adcc4ee8 221 Pfam PF00188 Cysteine-rich secretory protein family 45 156 2.1E-4 T 28-03-2018 IPR014044 CAP domain CP478_RS11200 c47d3b631a3966922054daf28c551942 237 Pfam PF01738 Dienelactone hydrolase family 13 228 3.0E-60 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CP478_RS11200 c47d3b631a3966922054daf28c551942 237 Gene3D G3DSA:3.40.50.1820 1 233 2.3E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11200 c47d3b631a3966922054daf28c551942 237 SUPERFAMILY SSF53474 2 229 2.81E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04260 f691441f07728ed1e5fd440dfab3b2c0 228 Gene3D G3DSA:3.20.20.370 17 209 2.2E-5 T 28-03-2018 CP478_RS04260 f691441f07728ed1e5fd440dfab3b2c0 228 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 9 132 9.3E-18 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CP478_RS04260 f691441f07728ed1e5fd440dfab3b2c0 228 SUPERFAMILY SSF88713 25 136 2.04E-5 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CP478_RS11250 07782bff0a10792f655444360bd68fc1 136 PIRSF PIRSF033490 2 113 1.1E-21 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS11250 07782bff0a10792f655444360bd68fc1 136 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 110 5.5E-19 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS11250 07782bff0a10792f655444360bd68fc1 136 SUPERFAMILY SSF50118 4 113 1.02E-20 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS11250 07782bff0a10792f655444360bd68fc1 136 Gene3D G3DSA:2.30.30.110 2 112 4.0E-19 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS16825 fa7debbd7206145c4fdf996278baa3a5 307 SUPERFAMILY SSF51621 23 240 5.93E-56 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CP478_RS16825 fa7debbd7206145c4fdf996278baa3a5 307 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 27 228 9.5E-29 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CP478_RS16825 fa7debbd7206145c4fdf996278baa3a5 307 Gene3D G3DSA:3.20.20.60 22 246 1.3E-40 T 28-03-2018 CP478_RS16825 fa7debbd7206145c4fdf996278baa3a5 307 PIRSF PIRSF015582 4 296 7.5E-77 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CP478_RS04500 89a337d4e02a46eb3db68023358aa2fb 301 Gene3D G3DSA:3.40.50.150 3 285 2.6E-55 T 28-03-2018 CP478_RS04500 89a337d4e02a46eb3db68023358aa2fb 301 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 272 2.6E-78 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS04500 89a337d4e02a46eb3db68023358aa2fb 301 Pfam PF04072 Leucine carboxyl methyltransferase 19 200 4.4E-61 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS04500 89a337d4e02a46eb3db68023358aa2fb 301 SUPERFAMILY SSF53335 15 284 9.14E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 SMART SM00732 22 123 1.5E-27 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 Pfam PF03652 Holliday junction resolvase 23 156 1.5E-41 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 25 155 1.9E-26 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 22 158 21.846 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 Gene3D G3DSA:3.30.420.140 20 168 2.7E-42 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CP478_RS14005 2926a692f5f439aaa3707b3924ca9f43 170 SUPERFAMILY SSF53098 22 156 1.82E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS21195 787ec194a6cb04d854d332e2a56592db 511 PIRSF PIRSF017804 14 511 3.7E-198 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS21195 787ec194a6cb04d854d332e2a56592db 511 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 23 107 3.2E-19 T 28-03-2018 IPR024962 YukD-like CP478_RS21195 787ec194a6cb04d854d332e2a56592db 511 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 25 508 1.8E-145 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS14225 ebb9da6b9c52da5b250330a5b9b76379 134 SUPERFAMILY SSF88723 5 129 5.89E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS14225 ebb9da6b9c52da5b250330a5b9b76379 134 Pfam PF01850 PIN domain 4 122 1.7E-11 T 28-03-2018 IPR002716 PIN domain CP478_RS14225 ebb9da6b9c52da5b250330a5b9b76379 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 130 14.596 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS14225 ebb9da6b9c52da5b250330a5b9b76379 134 Gene3D G3DSA:3.40.50.1010 2 133 2.8E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 SUPERFAMILY SSF53383 4 360 1.69E-73 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 5 361 1.9E-178 T 28-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 Gene3D G3DSA:3.40.640.10 34 265 7.0E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 Pfam PF00155 Aminotransferase class I and II 29 360 2.3E-41 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 Gene3D G3DSA:3.90.1150.10 266 361 4.0E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS06465 9a2a8a2c3e615b8b5265a62964fd40a3 362 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 SUPERFAMILY SSF52402 1 144 1.67E-30 T 28-03-2018 CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 Gene3D G3DSA:3.40.50.620 1 146 3.4E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 PRINTS PR01438 Universal stress protein signature 4 22 6.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 PRINTS PR01438 Universal stress protein signature 104 116 6.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 PRINTS PR01438 Universal stress protein signature 122 144 6.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CP478_RS08955 7ff221bd8bd7945532c7c34c26b142dc 146 Pfam PF00582 Universal stress protein family 4 144 3.5E-25 T 28-03-2018 IPR006016 UspA GO:0006950 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 Pfam PF00171 Aldehyde dehydrogenase family 38 477 3.7E-95 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 Gene3D G3DSA:3.40.309.10 272 462 6.4E-62 T 28-03-2018 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 SUPERFAMILY SSF53720 47 486 6.15E-124 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 PIRSF PIRSF036492 23 506 4.5E-175 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CP478_RS00795 95c9a395a13a96f56a6a0f9074e6c9b4 506 Gene3D G3DSA:3.40.605.10 11 271 1.0E-74 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS15165 e15c5429e6ac66c2b4c922efa28c6287 394 Pfam PF00823 PPE family 5 161 3.2E-59 T 28-03-2018 IPR000030 PPE family CP478_RS15165 e15c5429e6ac66c2b4c922efa28c6287 394 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 311 390 3.1E-19 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS15165 e15c5429e6ac66c2b4c922efa28c6287 394 SUPERFAMILY SSF140459 2 173 3.4E-60 T 28-03-2018 CP478_RS09595 a7337ac1a562b83ee7f80f5f077a006f 127 Pfam PF16817 Domain of unknown function (DUF5073) 1 121 8.2E-72 T 28-03-2018 IPR031816 Protein of unknown function DUF5073 CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 Pfam PF03308 ArgK protein 26 298 7.6E-124 T 28-03-2018 CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 SUPERFAMILY SSF52540 10 327 1.1E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 Gene3D G3DSA:1.20.5.170 13 54 8.0E-21 T 28-03-2018 CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 Gene3D G3DSA:1.10.287.130 268 328 2.5E-25 T 28-03-2018 CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 21 327 1.3E-138 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CP478_RS08200 b117cc792a4eb569331f4908605687bd 334 Gene3D G3DSA:3.40.50.300 56 266 5.4E-39 T 28-03-2018 CP478_RS19500 2586d0400d263907ead78fa0665f5098 187 SMART SM00903 14 159 2.2E-59 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS19500 2586d0400d263907ead78fa0665f5098 187 SUPERFAMILY SSF50475 5 159 2.06E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS19500 2586d0400d263907ead78fa0665f5098 187 Gene3D G3DSA:2.30.110.10 2 187 7.0E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS19500 2586d0400d263907ead78fa0665f5098 187 Pfam PF01613 Flavin reductase like domain 15 160 4.4E-37 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS04665 878ddd8c30ba130f12472d34a5d7144c 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 139 1.0E-19 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS04665 878ddd8c30ba130f12472d34a5d7144c 147 SUPERFAMILY SSF55961 1 143 2.54E-29 T 28-03-2018 CP478_RS04665 878ddd8c30ba130f12472d34a5d7144c 147 Gene3D G3DSA:3.30.530.20 5 144 1.1E-25 T 28-03-2018 IPR023393 START-like domain CP478_RS03155 8a8194a5eaf1180240f859eb64729d6d 404 Pfam PF02470 MlaD protein 44 124 9.2E-14 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS03155 8a8194a5eaf1180240f859eb64729d6d 404 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 306 3.4E-87 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03155 8a8194a5eaf1180240f859eb64729d6d 404 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 153 404 1.4E-104 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS05325 944dca3d614755c0a88c1db29c119dca 560 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 3 329 1.6E-130 T 28-03-2018 IPR010839 Acyclic terpene utilisation CP478_RS19610 a214203058557d689a3bafce830c1b44 304 SMART SM00478 50 201 1.1E-51 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 Gene3D G3DSA:1.10.1670.10 129 230 5.7E-30 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 SUPERFAMILY SSF48150 20 226 1.4E-62 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 Gene3D G3DSA:1.10.340.30 31 128 2.3E-28 T 28-03-2018 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 SMART SM00525 202 221 4.1E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 Pfam PF00633 Helix-hairpin-helix motif 111 139 3.6E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CP478_RS19610 a214203058557d689a3bafce830c1b44 304 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 46 161 9.6E-16 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS01805 f5005de256d6356cacdd0ff591b0316d 429 Gene3D G3DSA:3.90.1150.10 307 429 9.9E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS01805 f5005de256d6356cacdd0ff591b0316d 429 SUPERFAMILY SSF53383 31 424 3.23E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS01805 f5005de256d6356cacdd0ff591b0316d 429 Pfam PF00155 Aminotransferase class I and II 60 406 1.8E-45 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CP478_RS01805 f5005de256d6356cacdd0ff591b0316d 429 Gene3D G3DSA:3.40.640.10 77 306 2.7E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS13160 1d53ef9bd2d6d184df2062607da71773 325 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 301 1.0E-75 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 148 2.0E-46 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 Gene3D G3DSA:3.40.50.2300 1 161 3.4E-45 T 28-03-2018 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 SMART SM00226 5 152 7.1E-62 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 5.4E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 5.4E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 50 66 5.4E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 5.4E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CP478_RS12150 1187fd7395b7af03e0dc488a2ad1d310 163 SUPERFAMILY SSF52788 3 153 1.19E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CP478_RS10190 a5b993aacf190e4c84f5416a04ed4655 147 Gene3D G3DSA:2.30.110.10 1 146 7.4E-22 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS10190 a5b993aacf190e4c84f5416a04ed4655 147 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 3.2E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS10190 a5b993aacf190e4c84f5416a04ed4655 147 SUPERFAMILY SSF50475 13 145 4.32E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS10190 a5b993aacf190e4c84f5416a04ed4655 147 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 8 145 2.9E-33 T 28-03-2018 IPR019920 F420-binding domain, putative CP478_RS00520 f8daba7fdfd83a3258f698bf8984e089 282 Pfam PF13490 Putative zinc-finger 49 83 8.6E-10 T 28-03-2018 IPR027383 Putative zinc-finger CP478_RS04395 cd3c992c4f4cf769638372130b0c65cb 60 Pfam PF11273 Protein of unknown function (DUF3073) 2 58 2.4E-22 T 28-03-2018 IPR021426 Protein of unknown function DUF3073 CP478_RS16965 6ca60aab2aa74b020ad3b8a45c9593b7 283 Gene3D G3DSA:1.20.120.450 6 165 5.3E-26 T 28-03-2018 CP478_RS16965 6ca60aab2aa74b020ad3b8a45c9593b7 283 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 21 253 2.6E-43 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS16965 6ca60aab2aa74b020ad3b8a45c9593b7 283 Pfam PF07398 MDMPI C-terminal domain 179 272 3.2E-12 T 28-03-2018 IPR010872 MDMPI C-terminal CP478_RS16965 6ca60aab2aa74b020ad3b8a45c9593b7 283 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 160 1.4E-28 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CP478_RS16965 6ca60aab2aa74b020ad3b8a45c9593b7 283 SUPERFAMILY SSF109854 9 166 3.85E-27 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS10480 d1155da378a81479c48b93a0efeb7fb7 159 ProDom PD886639 ANTIGEN IMMUNOGENIC EXTRACELLULAR MPT63 MPB63 PRECURSOR IMMUNOPROTECTIVE SIGNAL SEQUENCING DIRECT 49 157 1.0E-57 T 28-03-2018 IPR015250 MPT63-like GO:0005615 CP478_RS10480 d1155da378a81479c48b93a0efeb7fb7 159 SUPERFAMILY SSF81982 30 158 5.23E-51 T 28-03-2018 IPR015250 MPT63-like GO:0005615 CP478_RS10480 d1155da378a81479c48b93a0efeb7fb7 159 Gene3D G3DSA:2.60.40.1240 29 159 3.0E-30 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CP478_RS10480 d1155da378a81479c48b93a0efeb7fb7 159 Pfam PF09167 Domain of unknown function (DUF1942) 33 157 3.3E-51 T 28-03-2018 IPR015250 MPT63-like GO:0005615 CP478_RS19775 1961691d7eea2a4e60d1c8d8cf6b5ac2 413 SUPERFAMILY SSF140459 3 175 4.71E-63 T 28-03-2018 CP478_RS19775 1961691d7eea2a4e60d1c8d8cf6b5ac2 413 Gene3D G3DSA:1.10.287.1060 23 102 4.5E-7 T 28-03-2018 CP478_RS19775 1961691d7eea2a4e60d1c8d8cf6b5ac2 413 Pfam PF00823 PPE family 7 162 6.7E-63 T 28-03-2018 IPR000030 PPE family CP478_RS19775 1961691d7eea2a4e60d1c8d8cf6b5ac2 413 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 329 409 2.6E-18 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS08630 2ac47cf04b028a2919ca1893162c77b0 473 Pfam PF05065 Phage capsid family 190 469 2.0E-47 T 28-03-2018 IPR024455 Phage capsid CP478_RS08630 2ac47cf04b028a2919ca1893162c77b0 473 Gene3D G3DSA:3.30.2400.10 212 354 1.1E-14 T 28-03-2018 CP478_RS08630 2ac47cf04b028a2919ca1893162c77b0 473 SUPERFAMILY SSF56563 186 469 1.31E-31 T 28-03-2018 CP478_RS08630 2ac47cf04b028a2919ca1893162c77b0 473 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 171 469 3.8E-42 T 28-03-2018 IPR024455 Phage capsid CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 7.2E-54 T 28-03-2018 CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 Gene3D G3DSA:3.40.50.720 1 260 3.5E-61 T 28-03-2018 CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 SUPERFAMILY SSF51735 6 257 3.46E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.2E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19300 cb680f162a476975d5fc905c5403bf01 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS03115 c8a0e8fb753b6da85045eaa2bc4c885e 71 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 1.0E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS03115 c8a0e8fb753b6da85045eaa2bc4c885e 71 SUPERFAMILY SSF47598 2 58 1.46E-8 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS03115 c8a0e8fb753b6da85045eaa2bc4c885e 71 Gene3D G3DSA:1.10.1220.10 2 48 1.9E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS02940 4b809b7b0369cafb8c29740366f65dea 137 Pfam PF01850 PIN domain 12 128 1.9E-10 T 28-03-2018 IPR002716 PIN domain CP478_RS02940 4b809b7b0369cafb8c29740366f65dea 137 Gene3D G3DSA:3.40.50.1010 3 136 2.9E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS02940 4b809b7b0369cafb8c29740366f65dea 137 SUPERFAMILY SSF88723 12 131 3.36E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS02940 4b809b7b0369cafb8c29740366f65dea 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 12 136 10.483 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS09230 60e765100dce740e510caedf033532f9 250 Gene3D G3DSA:1.25.40.10 162 242 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS09230 60e765100dce740e510caedf033532f9 250 Gene3D G3DSA:1.25.40.10 39 161 2.8E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS09230 60e765100dce740e510caedf033532f9 250 SUPERFAMILY SSF48452 69 229 4.43E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS19555 846069432c1a4f5cce7ac62e977fbb57 413 PRINTS PR00758 Arsenical pump membrane protein signature 175 198 7.7E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS19555 846069432c1a4f5cce7ac62e977fbb57 413 PRINTS PR00758 Arsenical pump membrane protein signature 347 372 7.7E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS19555 846069432c1a4f5cce7ac62e977fbb57 413 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 7.7E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS19555 846069432c1a4f5cce7ac62e977fbb57 413 PRINTS PR00758 Arsenical pump membrane protein signature 380 404 7.7E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS19555 846069432c1a4f5cce7ac62e977fbb57 413 Pfam PF02040 Arsenical pump membrane protein 3 399 1.5E-23 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS01795 ab0b230a6df685ec662fe6dcc9aff755 511 Gene3D G3DSA:3.40.1800.10 333 400 7.9E-6 T 28-03-2018 CP478_RS01795 ab0b230a6df685ec662fe6dcc9aff755 511 SMART SM00507 338 390 6.5E-5 T 28-03-2018 IPR003615 HNH nuclease CP478_RS01795 ab0b230a6df685ec662fe6dcc9aff755 511 Pfam PF02720 Domain of unknown function (DUF222) 41 347 1.0E-92 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS18420 3664c13ffc01f874e5bb86b3ee300177 122 Gene3D G3DSA:1.10.10.10 32 122 1.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18420 3664c13ffc01f874e5bb86b3ee300177 122 Pfam PF05331 Protein of unknown function (DUF742) 10 122 2.9E-35 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CP478_RS19140 e7fdd227dd5a9dfdf3c492ac9d4942b8 280 Pfam PF02405 Permease MlaE 64 267 2.3E-50 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS05280 7a6c9a45575ac23ddaa089d43e8dda67 119 Pfam PF02583 Metal-sensitive transcriptional repressor 9 87 1.6E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Gene3D G3DSA:3.40.50.300 350 730 6.3E-37 T 28-03-2018 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Pfam PF13361 UvrD-like helicase C-terminal domain 317 694 2.2E-13 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Gene3D G3DSA:3.40.50.300 8 302 9.6E-28 T 28-03-2018 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Pfam PF12705 PD-(D/E)XK nuclease superfamily 805 1047 1.3E-40 T 28-03-2018 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 SUPERFAMILY SSF52540 496 718 7.53E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17550 f624597721d421155cb04604977ec18a 1055 SUPERFAMILY SSF52540 12 466 7.53E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Gene3D G3DSA:3.90.320.10 778 977 1.5E-11 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CP478_RS17550 f624597721d421155cb04604977ec18a 1055 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 301 1.5E-35 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CP478_RS21150 291d01e45302869bccc586c5d8802475 480 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 464 1.4E-161 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS21150 291d01e45302869bccc586c5d8802475 480 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 452 8.5E-169 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS02540 413217c087345501759948d84f8370d7 87 Pfam PF10724 Protein of unknown function (DUF2516) 1 84 1.4E-25 T 28-03-2018 IPR019662 Protein of unknown function DUF2516 CP478_RS18240 76fcd200f449f06339ca36c784be2c32 405 Gene3D G3DSA:3.40.710.10 67 368 4.3E-56 T 28-03-2018 CP478_RS18240 76fcd200f449f06339ca36c784be2c32 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 131 1.1E-6 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CP478_RS18240 76fcd200f449f06339ca36c784be2c32 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 168 185 1.1E-6 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CP478_RS18240 76fcd200f449f06339ca36c784be2c32 405 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 88 310 8.6E-36 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CP478_RS18240 76fcd200f449f06339ca36c784be2c32 405 SUPERFAMILY SSF56601 78 331 4.91E-55 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS01730 978bd6f10d518293c93fb7e5b7285f3a 223 SUPERFAMILY SSF102588 12 207 1.24E-39 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS01730 978bd6f10d518293c93fb7e5b7285f3a 223 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 137 5.8E-26 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CP478_RS01730 978bd6f10d518293c93fb7e5b7285f3a 223 Gene3D G3DSA:3.40.50.10320 10 220 2.1E-37 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CP478_RS01175 77667d56741d553299adf373f7ecf9a7 302 Pfam PF07859 alpha/beta hydrolase fold 74 271 3.4E-60 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS01175 77667d56741d553299adf373f7ecf9a7 302 SUPERFAMILY SSF53474 44 296 7.75E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01175 77667d56741d553299adf373f7ecf9a7 302 Gene3D G3DSA:3.40.50.1820 37 302 1.7E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11410 4dfa954cd6d7140c683b99267fcd8134 316 Pfam PF13280 WYL domain 140 306 3.5E-31 T 28-03-2018 IPR026881 WYL domain CP478_RS11410 4dfa954cd6d7140c683b99267fcd8134 316 Gene3D G3DSA:1.10.10.10 2 62 2.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11410 4dfa954cd6d7140c683b99267fcd8134 316 PIRSF PIRSF016838 1 315 5.8E-121 T 28-03-2018 IPR028349 Protein PafC CP478_RS09135 a0f26c65d8908c6bb62ef5cbbe1d26a2 443 Gene3D G3DSA:1.20.1250.20 9 218 8.1E-34 T 28-03-2018 CP478_RS09135 a0f26c65d8908c6bb62ef5cbbe1d26a2 443 Pfam PF07690 Major Facilitator Superfamily 24 348 3.6E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS09135 a0f26c65d8908c6bb62ef5cbbe1d26a2 443 SUPERFAMILY SSF103473 11 420 1.44E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS09135 a0f26c65d8908c6bb62ef5cbbe1d26a2 443 Gene3D G3DSA:1.20.1250.20 236 427 1.8E-10 T 28-03-2018 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 PIRSF PIRSF000460 1 807 2.9E-280 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 610 622 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 Pfam PF00343 Carbohydrate phosphorylase 131 176 1.2E-5 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 Pfam PF00343 Carbohydrate phosphorylase 235 632 3.0E-20 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 SUPERFAMILY SSF53756 4 754 2.74E-203 T 28-03-2018 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 Gene3D G3DSA:3.40.50.2000 435 756 2.2E-79 T 28-03-2018 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 Gene3D G3DSA:3.40.50.2000 120 434 1.5E-86 T 28-03-2018 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 Pfam PF11897 Protein of unknown function (DUF3417) 13 126 1.7E-35 T 28-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS07285 82a2118b327740b88f90b048bc492972 863 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 113 721 5.5E-235 T 28-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CP478_RS04965 aa8685e8c3985c84c1ad57eab4dc641f 257 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 251 2.5E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS04965 aa8685e8c3985c84c1ad57eab4dc641f 257 Gene3D G3DSA:3.10.180.10 138 256 1.9E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04965 aa8685e8c3985c84c1ad57eab4dc641f 257 Gene3D G3DSA:3.10.180.10 1 133 1.1E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04965 aa8685e8c3985c84c1ad57eab4dc641f 257 SUPERFAMILY SSF54593 140 252 3.03E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04965 aa8685e8c3985c84c1ad57eab4dc641f 257 SUPERFAMILY SSF54593 11 167 1.93E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS11695 ef30b803b293bc15812985e3f6549d51 250 Gene3D G3DSA:3.60.140.10 12 250 6.2E-84 T 28-03-2018 CP478_RS11695 ef30b803b293bc15812985e3f6549d51 250 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 30 250 9.6E-70 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CP478_RS11695 ef30b803b293bc15812985e3f6549d51 250 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 25 248 8.1E-71 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CP478_RS11695 ef30b803b293bc15812985e3f6549d51 250 SUPERFAMILY SSF64438 19 250 1.83E-74 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CP478_RS17020 4150ec720db4161dd617dbba2fb7ea6e 131 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 32 119 9.4E-22 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS17020 4150ec720db4161dd617dbba2fb7ea6e 131 Gene3D G3DSA:3.30.1360.20 23 124 5.1E-23 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS17020 4150ec720db4161dd617dbba2fb7ea6e 131 SUPERFAMILY SSF55248 32 121 3.53E-23 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS20405 3747f92715b14a168f0004393134f4a3 162 Gene3D G3DSA:3.40.1520.10 3 161 9.2E-76 T 28-03-2018 IPR007153 Adenosine specific kinase CP478_RS20405 3747f92715b14a168f0004393134f4a3 162 SUPERFAMILY SSF103165 5 162 2.35E-70 T 28-03-2018 IPR007153 Adenosine specific kinase CP478_RS20405 3747f92715b14a168f0004393134f4a3 162 Pfam PF04008 Adenosine specific kinase 8 161 9.3E-73 T 28-03-2018 IPR007153 Adenosine specific kinase CP478_RS07330 3647d841cdde5df56a1ed224bffa751d 240 Pfam PF01694 Rhomboid family 73 220 1.4E-25 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS07330 3647d841cdde5df56a1ed224bffa751d 240 SUPERFAMILY SSF144091 43 223 1.31E-27 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS07330 3647d841cdde5df56a1ed224bffa751d 240 Gene3D G3DSA:1.20.1540.10 32 220 1.1E-19 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 64 241 4.7E-57 T 28-03-2018 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 Pfam PF08659 KR domain 64 239 1.3E-58 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 Pfam PF00550 Phosphopantetheine attachment site 347 410 4.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 SUPERFAMILY SSF47336 336 420 1.02E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 SUPERFAMILY SSF51735 61 295 3.12E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 SMART SM00823 Phosphopantetheine attachment site 343 414 1.2E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 ProSitePatterns PS00012 Phosphopantetheine attachment site. 369 384 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 SMART SM01294 343 410 2.0E-7 T 28-03-2018 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 Gene3D G3DSA:3.90.180.10 1 58 1.9E-6 T 28-03-2018 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 Gene3D G3DSA:3.40.50.720 59 304 8.5E-50 T 28-03-2018 CP478_RS09095 a30f13c9518f146aa71a2fe0ca29128f 502 Gene3D G3DSA:1.10.1200.10 336 445 6.4E-23 T 28-03-2018 CP478_RS12155 2e9349a6ee4150d7ace8a4a424e1ce71 271 Pfam PF02104 SURF1 family 24 225 2.0E-24 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.8E-28 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Gene3D G3DSA:3.40.50.20 2 84 4.1E-32 T 28-03-2018 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 38.589 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Gene3D G3DSA:3.30.470.20 188 325 5.4E-52 T 28-03-2018 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 SMART SM01210 327 416 5.5E-38 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 286 293 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Gene3D G3DSA:3.30.1490.20 85 186 2.1E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 SMART SM01209 101 292 1.2E-97 T 28-03-2018 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 SUPERFAMILY SSF51246 326 415 1.1E-23 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 SUPERFAMILY SSF52440 2 101 2.45E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 SUPERFAMILY SSF56059 102 317 2.05E-48 T 28-03-2018 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 292 1.2E-60 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 328 414 2.3E-24 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 416 1.3E-151 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04200 fdea095fe5f15e89c669cee750809409 422 Gene3D G3DSA:3.90.600.10 327 417 5.3E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS09285 cd6468028c3ecc45e1beaa8c1c2f25d9 454 Pfam PF02720 Domain of unknown function (DUF222) 36 361 4.7E-106 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS09285 cd6468028c3ecc45e1beaa8c1c2f25d9 454 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 1 96 2.0E-49 T 28-03-2018 CP478_RS09285 cd6468028c3ecc45e1beaa8c1c2f25d9 454 SMART SM00507 352 404 6.7E-4 T 28-03-2018 IPR003615 HNH nuclease CP478_RS16560 aa1d5ef9f72b68170b93d1fe3327200e 281 Pfam PF13444 Acetyltransferase (GNAT) domain 43 145 5.8E-28 T 28-03-2018 CP478_RS16560 aa1d5ef9f72b68170b93d1fe3327200e 281 SUPERFAMILY SSF55729 25 243 2.66E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS16560 aa1d5ef9f72b68170b93d1fe3327200e 281 Gene3D G3DSA:3.40.630.30 28 169 8.5E-32 T 28-03-2018 CP478_RS19145 7daba61cc4d837d89ef719b4553badc8 254 Pfam PF02405 Permease MlaE 36 247 1.7E-60 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 Gene3D G3DSA:3.40.720.10 209 663 2.6E-99 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 Pfam PF00884 Sulfatase 212 634 2.2E-101 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 Pfam PF06897 Protein of unknown function (DUF1269) 66 144 2.7E-9 T 28-03-2018 IPR009200 Protein of unknown function DUF1269, membrane associated CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 Gene3D G3DSA:3.30.1120.10 664 765 6.6E-14 T 28-03-2018 CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 ProSitePatterns PS00523 Sulfatases signature 1. 256 268 - T 28-03-2018 IPR024607 Sulfatase, conserved site CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 SUPERFAMILY SSF53649 211 755 3.05E-130 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CP478_RS18075 27b2e7662ea2c960f2d9abf5b7cf62fd 970 Gene3D G3DSA:2.60.120.200 769 960 1.2E-6 T 28-03-2018 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 18.742 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 SUPERFAMILY SSF82697 3 75 1.5E-22 T 28-03-2018 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 74 7.4E-24 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 5.5E-14 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 Gene3D G3DSA:3.30.1280.10 3 77 2.7E-24 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS04280 fd012ac220e1f55e32c54548bf0ea905 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 6.0E-24 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CP478_RS18175 beb700f950aa010be0289489a29325e3 144 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 18 126 2.0E-16 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18175 beb700f950aa010be0289489a29325e3 144 SUPERFAMILY SSF81343 18 141 2.83E-32 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18175 beb700f950aa010be0289489a29325e3 144 Gene3D G3DSA:1.20.1300.10 27 144 2.3E-22 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 SUPERFAMILY SSF53850 228 553 4.19E-50 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 SUPERFAMILY SSF53850 42 197 4.19E-50 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 Gene3D G3DSA:3.90.76.10 27 185 3.2E-7 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 Gene3D G3DSA:3.40.190.10 186 331 7.3E-14 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 Gene3D G3DSA:3.10.105.10 332 525 4.7E-25 T 28-03-2018 CP478_RS14165 d969ff87f7ba32e7179b7c6d1f1e7ed2 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 459 9.9E-16 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 SUPERFAMILY SSF53041 52 182 1.83E-18 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 ProSitePatterns PS00397 Site-specific recombinases active site. 55 63 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 Gene3D G3DSA:1.10.1660.20 1 43 7.5E-6 T 28-03-2018 CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 Pfam PF00239 Resolvase, N terminal domain 53 188 8.2E-18 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 SMART SM00857 52 187 6.1E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CP478_RS16290 49fae607bc1253e56d06329e87820b9a 194 Gene3D G3DSA:3.40.50.1390 48 193 3.5E-21 T 28-03-2018 CP478_RS03365 4a01373fb393adec0247228d668d7297 86 SUPERFAMILY SSF143120 1 46 4.32E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS03365 4a01373fb393adec0247228d668d7297 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 56 4.7E-17 T 28-03-2018 CP478_RS03365 4a01373fb393adec0247228d668d7297 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 55 1.3E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS03365 4a01373fb393adec0247228d668d7297 86 Gene3D G3DSA:3.40.1620.10 1 72 4.1E-13 T 28-03-2018 CP478_RS01590 40f36eeec02710dad6369e58f5559bd0 267 Gene3D G3DSA:3.40.50.300 4 264 6.7E-26 T 28-03-2018 CP478_RS01590 40f36eeec02710dad6369e58f5559bd0 267 SUPERFAMILY SSF52540 7 266 8.18E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01590 40f36eeec02710dad6369e58f5559bd0 267 Pfam PF09037 Stf0 sulphotransferase 8 259 1.0E-105 T 28-03-2018 IPR024628 Sulphotransferase Stf0, domain MetaCyc: PWY-7746 CP478_RS01590 40f36eeec02710dad6369e58f5559bd0 267 PIRSF PIRSF021497 1 267 2.9E-112 T 28-03-2018 IPR015124 Trehalose 2-sulfotransferase GO:0016740 MetaCyc: PWY-7746 CP478_RS00955 a3164321b5872088bd7287ff4917cd51 515 Pfam PF02470 MlaD protein 39 112 6.0E-17 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS00955 a3164321b5872088bd7287ff4917cd51 515 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 294 8.2E-90 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 TIGRFAM TIGR04343 egtE_PLP_lyase: ergothioneine biosynthesis PLP-dependent enzyme EgtE 14 380 5.4E-181 T 28-03-2018 IPR027563 Pyridoxal-phosphate-dependent protein EgtE CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 SUPERFAMILY SSF53383 29 382 4.13E-54 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 Gene3D G3DSA:3.40.640.10 33 263 7.4E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 Pfam PF00266 Aminotransferase class-V 30 375 1.8E-32 T 28-03-2018 IPR000192 Aminotransferase class V domain CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 Hamap MF_02038 Probable hercynylcysteine sulfoxide lyase [egtE]. 12 381 36.064 T 28-03-2018 IPR027563 Pyridoxal-phosphate-dependent protein EgtE CP478_RS20215 a0bed925550f0ba82ded96d53aaf1123 390 Gene3D G3DSA:3.90.1150.10 264 389 1.7E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS04880 3ef1193010e4d6ca2480afea66752ad0 393 SUPERFAMILY SSF52540 39 285 3.12E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS04880 3ef1193010e4d6ca2480afea66752ad0 393 Gene3D G3DSA:3.40.50.300 28 175 2.3E-13 T 28-03-2018 CP478_RS11330 54689ce8c929c293fe0c2a595d671c44 104 Pfam PF10817 Protein of unknown function (DUF2563) 1 104 6.6E-58 T 28-03-2018 IPR022534 Protein of unknown function DUF2563 CP478_RS11330 54689ce8c929c293fe0c2a595d671c44 104 ProDom PD069409 MB2104 RV2078/MT2139 1 104 9.0E-55 T 28-03-2018 IPR022534 Protein of unknown function DUF2563 CP478_RS11330 54689ce8c929c293fe0c2a595d671c44 104 Gene3D G3DSA:1.10.287.1060 1 98 3.3E-5 T 28-03-2018 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.591 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 4.2E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 Pfam PF01250 Ribosomal protein S6 4 92 4.2E-28 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 SUPERFAMILY SSF54995 1 95 2.62E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00290 72d6224e68803f5c05526fd3747d596b 96 Gene3D G3DSA:3.30.70.60 1 96 7.6E-29 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 SUPERFAMILY SSF50494 49 253 5.87E-41 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 SUPERFAMILY SSF50156 279 353 9.86E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 Gene3D G3DSA:2.30.42.10 267 352 2.8E-13 T 28-03-2018 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 Pfam PF13365 Trypsin-like peptidase domain 79 222 7.6E-23 T 28-03-2018 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 88 100 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 215 232 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 110 130 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 PRINTS PR00834 HtrA/DegQ protease family signature 193 210 3.9E-26 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 SMART SM00228 268 341 1.1E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 Gene3D G3DSA:2.40.10.10 152 253 3.3E-23 T 28-03-2018 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 Gene3D G3DSA:2.40.10.10 48 151 2.2E-23 T 28-03-2018 CP478_RS00685 45b534336035aedc596a70ae9a23616c 355 Pfam PF13180 PDZ domain 269 337 8.2E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CP478_RS07795 5c1cfaa2e0b091b827570f80e5652131 459 SUPERFAMILY SSF52777 4 159 1.22E-9 T 28-03-2018 CP478_RS07795 5c1cfaa2e0b091b827570f80e5652131 459 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 458 9.9E-160 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS07795 5c1cfaa2e0b091b827570f80e5652131 459 Pfam PF06974 Protein of unknown function (DUF1298) 305 454 3.9E-34 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS07795 5c1cfaa2e0b091b827570f80e5652131 459 Gene3D G3DSA:3.30.559.10 6 295 1.2E-5 T 28-03-2018 CP478_RS07795 5c1cfaa2e0b091b827570f80e5652131 459 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 264 9.1E-89 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS15585 d757ecd9256eeea89130f7d0a9a0ed6f 156 Gene3D G3DSA:3.40.630.30 1 155 2.4E-24 T 28-03-2018 CP478_RS15585 d757ecd9256eeea89130f7d0a9a0ed6f 156 SUPERFAMILY SSF55729 13 148 6.13E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS15585 d757ecd9256eeea89130f7d0a9a0ed6f 156 Pfam PF13673 Acetyltransferase (GNAT) domain 46 146 4.7E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS02130 25e5ef372342dca1caf7de882f29c368 409 Gene3D G3DSA:3.40.710.10 24 393 8.6E-50 T 28-03-2018 CP478_RS02130 25e5ef372342dca1caf7de882f29c368 409 Pfam PF00144 Beta-lactamase 42 388 5.6E-57 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS02130 25e5ef372342dca1caf7de882f29c368 409 SUPERFAMILY SSF56601 38 372 7.42E-56 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS04615 ddeb5ea95b17025640cdb703900273da 425 Gene3D G3DSA:3.30.565.10 291 425 1.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04615 ddeb5ea95b17025640cdb703900273da 425 SUPERFAMILY SSF55874 322 422 3.14E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS04615 ddeb5ea95b17025640cdb703900273da 425 SMART SM00387 329 425 4.7E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS19280 6673aae0d4e779f5d0f2ce810e7d58b6 237 SUPERFAMILY SSF53335 163 228 8.32E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS19280 6673aae0d4e779f5d0f2ce810e7d58b6 237 SUPERFAMILY SSF53335 44 134 8.32E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS19280 6673aae0d4e779f5d0f2ce810e7d58b6 237 Gene3D G3DSA:3.40.50.150 18 223 3.4E-4 T 28-03-2018 CP478_RS21045 43de444b492d18146140c319e25cd2ea 132 Gene3D G3DSA:1.10.260.40 1 92 2.4E-11 T 28-03-2018 CP478_RS21245 5f7627639c6c03bdb5a7a864e7ffcf6f 509 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 15 509 7.6E-138 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CP478_RS21245 5f7627639c6c03bdb5a7a864e7ffcf6f 509 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 13 93 2.5E-11 T 28-03-2018 IPR024962 YukD-like CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 SUPERFAMILY SSF140459 8 84 1.44E-21 T 28-03-2018 CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 PRINTS PR01228 Eggshell protein signature 315 333 1.7E-5 T 28-03-2018 CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 PRINTS PR01228 Eggshell protein signature 184 195 1.7E-5 T 28-03-2018 CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 PRINTS PR01228 Eggshell protein signature 288 298 1.7E-5 T 28-03-2018 CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 PRINTS PR01228 Eggshell protein signature 257 272 1.7E-5 T 28-03-2018 CP478_RS19175 1d65abfef73b9b03a2f2a5fa07496efc 1384 Pfam PF00934 PE family 1 93 1.1E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS10720 854fbc1da6a0a98b10359cdb9fdff098 423 Gene3D G3DSA:1.10.287.1060 230 298 0.012 T 28-03-2018 CP478_RS10720 854fbc1da6a0a98b10359cdb9fdff098 423 Gene3D G3DSA:1.10.287.1060 151 229 0.26 T 28-03-2018 CP478_RS10720 854fbc1da6a0a98b10359cdb9fdff098 423 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 298 4.1E-84 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10720 854fbc1da6a0a98b10359cdb9fdff098 423 Pfam PF02470 MlaD protein 35 108 1.0E-11 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 Gene3D G3DSA:1.20.1090.10 175 357 1.1E-57 T 28-03-2018 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 Gene3D G3DSA:3.40.50.1970 7 174 2.2E-42 T 28-03-2018 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 358 36.942 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 SUPERFAMILY SSF56796 14 356 1.23E-100 T 28-03-2018 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 PIRSF PIRSF001455 8 347 3.4E-95 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 Pfam PF01761 3-dehydroquinate synthase 69 325 1.5E-92 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CP478_RS13910 0f6ad45726f188164ebeef06a9d76b94 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 18 341 1.4E-102 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CP478_RS17970 844588c681898604608ef6eedbf64a14 172 Pfam PF03703 Bacterial PH domain 82 156 3.3E-19 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CP478_RS06435 9f33eae9be4e7f853063d93c24cf1058 308 SUPERFAMILY SSF140459 8 85 5.75E-24 T 28-03-2018 CP478_RS06435 9f33eae9be4e7f853063d93c24cf1058 308 Pfam PF00934 PE family 1 93 3.3E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS17905 1929f54b2e6e4afccc6e46474305390b 301 Pfam PF00535 Glycosyl transferase family 2 1 191 4.5E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS17905 1929f54b2e6e4afccc6e46474305390b 301 Gene3D G3DSA:3.90.550.10 1 297 1.1E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS17905 1929f54b2e6e4afccc6e46474305390b 301 SUPERFAMILY SSF53448 1 271 5.63E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS12415 e1e3bf09b5f598ce5bf60f24448ced48 445 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 443 1.2E-140 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS12415 e1e3bf09b5f598ce5bf60f24448ced48 445 Gene3D G3DSA:3.30.559.10 2 187 1.0E-6 T 28-03-2018 CP478_RS12415 e1e3bf09b5f598ce5bf60f24448ced48 445 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 256 3.8E-83 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS12415 e1e3bf09b5f598ce5bf60f24448ced48 445 SUPERFAMILY SSF52777 69 153 1.22E-7 T 28-03-2018 CP478_RS12415 e1e3bf09b5f598ce5bf60f24448ced48 445 Pfam PF06974 Protein of unknown function (DUF1298) 295 439 3.4E-25 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS04600 af2187b381d7fff94464912cc37aebe5 430 Gene3D G3DSA:1.20.1250.20 20 208 7.3E-20 T 28-03-2018 CP478_RS04600 af2187b381d7fff94464912cc37aebe5 430 Pfam PF07690 Major Facilitator Superfamily 54 254 1.6E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS04600 af2187b381d7fff94464912cc37aebe5 430 SUPERFAMILY SSF103473 21 409 1.14E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS04600 af2187b381d7fff94464912cc37aebe5 430 Gene3D G3DSA:1.20.1250.20 216 413 4.6E-11 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Pfam PF00501 AMP-binding enzyme 24 394 1.4E-58 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Gene3D G3DSA:3.30.300.30 389 495 2.3E-14 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Gene3D G3DSA:3.40.50.980 161 313 1.5E-30 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Gene3D G3DSA:3.40.50.980 5 160 6.1E-19 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Gene3D G3DSA:2.30.38.10 316 388 6.6E-19 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 SUPERFAMILY SSF56801 23 491 1.96E-95 T 28-03-2018 CP478_RS19170 921cdf64930f221ca35b42a92f055a49 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 404 480 6.8E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS07735 e50eb21ba0f4c7aa13f76197bf69e5d4 173 Pfam PF01168 Alanine racemase, N-terminal domain 2 159 4.8E-16 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS07735 e50eb21ba0f4c7aa13f76197bf69e5d4 173 SUPERFAMILY SSF51419 2 164 2.99E-18 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS07735 e50eb21ba0f4c7aa13f76197bf69e5d4 173 Gene3D G3DSA:3.20.20.10 1 167 1.7E-24 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 Gene3D G3DSA:2.120.10.30 81 225 2.7E-11 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 Gene3D G3DSA:2.120.10.30 226 341 1.5E-16 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 Pfam PF01436 NHL repeat 149 172 1.5E-4 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 Pfam PF01436 NHL repeat 272 298 3.8E-6 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 Pfam PF01436 NHL repeat 231 255 1.8E-4 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CP478_RS19260 cd02c4d9a174ca2b6db99d460f834623 343 SUPERFAMILY SSF101898 93 338 1.83E-40 T 28-03-2018 CP478_RS00225 1f4cb89e38667edbbb0f4d2ccec8f10a 310 Gene3D G3DSA:3.40.1000.10 130 271 2.3E-17 T 28-03-2018 CP478_RS00225 1f4cb89e38667edbbb0f4d2ccec8f10a 310 Pfam PF10738 Probable lipoprotein LpqN 103 270 1.0E-62 T 28-03-2018 IPR019674 Lipoprotein LpqT, predicted CP478_RS03180 4eded0f6f8b98a266b1f8b928622637b 516 Gene3D G3DSA:1.20.120.570 155 292 4.5E-4 T 28-03-2018 CP478_RS03180 4eded0f6f8b98a266b1f8b928622637b 516 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 292 1.0E-89 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03180 4eded0f6f8b98a266b1f8b928622637b 516 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 154 280 4.4E-7 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CP478_RS03180 4eded0f6f8b98a266b1f8b928622637b 516 Pfam PF02470 MlaD protein 40 112 1.2E-15 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS20205 2991bdeb9d2c992c0b17ef35f20f11d1 509 SUPERFAMILY SSF55931 57 475 1.18E-43 T 28-03-2018 CP478_RS20205 2991bdeb9d2c992c0b17ef35f20f11d1 509 PIRSF PIRSF012666 12 509 2.6E-249 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 Pfam PF13177 DNA polymerase III, delta subunit 17 175 1.3E-37 T 28-03-2018 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 Gene3D G3DSA:1.10.8.60 166 242 9.3E-12 T 28-03-2018 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 362 1.1E-14 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 360 5.9E-113 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 SUPERFAMILY SSF52540 31 223 3.08E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 Gene3D G3DSA:3.40.50.300 1 165 6.2E-37 T 28-03-2018 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 Gene3D G3DSA:1.20.272.10 243 365 1.3E-20 T 28-03-2018 CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 SMART SM00382 34 177 3.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS20325 fb31e664ec4ab9d7810cb01b0df5c84b 578 SUPERFAMILY SSF48019 244 361 2.04E-22 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CP478_RS07310 befc0c38e556e2fbb16ac3831fe54579 344 SUPERFAMILY SSF56266 1 339 3.92E-80 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS07310 befc0c38e556e2fbb16ac3831fe54579 344 Pfam PF03576 Peptidase family S58 2 330 4.0E-72 T 28-03-2018 IPR005321 Peptidase S58, DmpA CP478_RS07310 befc0c38e556e2fbb16ac3831fe54579 344 Gene3D G3DSA:3.60.70.12 1 341 6.2E-108 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CP478_RS15010 142034ce12c1954e9d73b751539eb5f3 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 285 369 1.2E-7 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CP478_RS15010 142034ce12c1954e9d73b751539eb5f3 388 Gene3D G3DSA:3.40.50.2000 1 225 4.0E-24 T 28-03-2018 CP478_RS15010 142034ce12c1954e9d73b751539eb5f3 388 SUPERFAMILY SSF53756 1 381 3.14E-58 T 28-03-2018 CP478_RS15010 142034ce12c1954e9d73b751539eb5f3 388 Gene3D G3DSA:3.40.50.2000 226 372 2.9E-23 T 28-03-2018 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 382 513 7.8E-19 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 SMART SM00382 377 516 7.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 68 623 5.5E-254 T 28-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 380 395 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 484 501 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 463 475 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 432 451 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 501 520 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 418 432 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 571 583 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 PRINTS PR00819 CbxX/CfqX superfamily signature 340 354 5.8E-54 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 Gene3D G3DSA:1.10.8.60 507 618 7.3E-4 T 28-03-2018 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 SUPERFAMILY SSF52540 339 550 3.06E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 Gene3D G3DSA:3.40.50.300 322 506 1.3E-24 T 28-03-2018 CP478_RS01525 9e4a2422017d0b88271817960ca0ea60 631 Gene3D G3DSA:1.25.40.10 42 292 0.0025 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 SUPERFAMILY SSF53187 190 373 1.29E-36 T 28-03-2018 CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Gene3D G3DSA:1.10.101.10 97 161 1.1E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Gene3D G3DSA:1.10.101.10 3 93 5.3E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 SUPERFAMILY SSF47090 10 83 7.59E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Pfam PF01471 Putative peptidoglycan binding domain 105 160 4.4E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Pfam PF01471 Putative peptidoglycan binding domain 18 83 4.4E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 SMART SM00646 255 370 3.5E-34 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 193 370 1.8E-29 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 SUPERFAMILY SSF47090 102 161 6.8E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CP478_RS21390 fd8c57fc759cdbca1cbddc3f78c73d4b 406 Gene3D G3DSA:3.40.630.40 188 379 6.9E-38 T 28-03-2018 CP478_RS00535 8fbe8cf0cdb3c565351cb1cf2c87a62f 463 SUPERFAMILY SSF140459 1 171 2.2E-58 T 28-03-2018 CP478_RS00535 8fbe8cf0cdb3c565351cb1cf2c87a62f 463 Pfam PF00823 PPE family 2 158 7.9E-59 T 28-03-2018 IPR000030 PPE family CP478_RS00535 8fbe8cf0cdb3c565351cb1cf2c87a62f 463 Gene3D G3DSA:1.10.287.1060 16 102 1.7E-4 T 28-03-2018 CP478_RS01540 b9fa0c8892482830c72d8cd048943806 102 Gene3D G3DSA:1.10.287.1060 1 100 5.4E-5 T 28-03-2018 CP478_RS01540 b9fa0c8892482830c72d8cd048943806 102 Pfam PF00934 PE family 3 92 4.6E-22 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS01540 b9fa0c8892482830c72d8cd048943806 102 ProDom PD195452 PE FAMILY PRECURSOR PE-FAMILY SIGNAL PE15 PE_1 47 81 2.0E-11 T 28-03-2018 CP478_RS01540 b9fa0c8892482830c72d8cd048943806 102 SUPERFAMILY SSF140459 7 73 4.71E-13 T 28-03-2018 CP478_RS17935 f130a55aba7fbb5556d3dcd76b0af1ac 222 SUPERFAMILY SSF161111 29 218 1.12E-21 T 28-03-2018 CP478_RS17935 f130a55aba7fbb5556d3dcd76b0af1ac 222 Gene3D G3DSA:1.20.1510.10 30 219 2.1E-14 T 28-03-2018 CP478_RS17935 f130a55aba7fbb5556d3dcd76b0af1ac 222 Pfam PF01545 Cation efflux family 101 213 4.2E-9 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CP478_RS05560 812dc1fffd775cb660efd197a1f6d7a1 226 Pfam PF10738 Probable lipoprotein LpqN 57 224 5.1E-63 T 28-03-2018 IPR019674 Lipoprotein LpqT, predicted CP478_RS05560 812dc1fffd775cb660efd197a1f6d7a1 226 Gene3D G3DSA:3.40.1000.10 84 224 7.7E-16 T 28-03-2018 CP478_RS03450 91b3ad2912a994fcb92d9b5f4d6816b9 161 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 108 136 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03450 91b3ad2912a994fcb92d9b5f4d6816b9 161 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 107 158 9.3E-18 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03450 91b3ad2912a994fcb92d9b5f4d6816b9 161 Hamap MF_00422 Protein translocase subunit SecE [secE]. 103 158 12.522 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CP478_RS03450 91b3ad2912a994fcb92d9b5f4d6816b9 161 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 106 161 1.0E-21 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CP478_RS03450 91b3ad2912a994fcb92d9b5f4d6816b9 161 Gene3D G3DSA:1.20.5.1030 105 156 9.2E-19 T 28-03-2018 CP478_RS02320 72a6c891b0b1ee59347b370cabe3c713 286 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 57 79 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS02320 72a6c891b0b1ee59347b370cabe3c713 286 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 21 186 2.6E-34 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CP478_RS02320 72a6c891b0b1ee59347b370cabe3c713 286 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 79 8.7E-11 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 92 103 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 278 289 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 354 365 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 295 322 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 155 170 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 195 217 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 138 154 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 PRINTS PR00359 B-class P450 signature 345 354 2.5E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 Gene3D G3DSA:1.10.630.10 1 405 6.8E-64 T 28-03-2018 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 SUPERFAMILY SSF48264 14 404 5.63E-83 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS06875 a0116604271a315c9d76141b5b5c33e9 405 Pfam PF00067 Cytochrome P450 279 375 2.1E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS02360 c00df68c8ec36388c0f411d4c9517e12 232 Pfam PF10099 Anti-sigma-K factor rskA 60 228 1.7E-26 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CP478_RS07665 dc9fe5ac5b424f225106c1a20960ad62 319 SUPERFAMILY SSF53474 56 317 1.64E-70 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07665 dc9fe5ac5b424f225106c1a20960ad62 319 Gene3D G3DSA:3.40.50.1820 9 319 1.5E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS07665 dc9fe5ac5b424f225106c1a20960ad62 319 Pfam PF07859 alpha/beta hydrolase fold 84 293 1.8E-71 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CP478_RS02165 f1cace7bb14b6d1ddcb41ee76aa6e910 272 Pfam PF00753 Metallo-beta-lactamase superfamily 37 245 2.7E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02165 f1cace7bb14b6d1ddcb41ee76aa6e910 272 SMART SM00849 38 245 5.5E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02165 f1cace7bb14b6d1ddcb41ee76aa6e910 272 SUPERFAMILY SSF56281 14 252 1.04E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02165 f1cace7bb14b6d1ddcb41ee76aa6e910 272 Gene3D G3DSA:3.60.15.10 9 271 4.1E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS10370 89239780e591de40fac833eafc49173f 320 SUPERFAMILY SSF54373 189 278 1.96E-16 T 28-03-2018 CP478_RS10370 89239780e591de40fac833eafc49173f 320 Gene3D G3DSA:3.30.9.10 145 275 2.8E-28 T 28-03-2018 CP478_RS10370 89239780e591de40fac833eafc49173f 320 Gene3D G3DSA:3.40.50.720 4 44 1.6E-6 T 28-03-2018 CP478_RS10370 89239780e591de40fac833eafc49173f 320 PIRSF PIRSF000189 5 319 6.4E-71 T 28-03-2018 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Reactome: R-HSA-389661 CP478_RS10370 89239780e591de40fac833eafc49173f 320 SUPERFAMILY SSF51971 266 319 1.12E-28 T 28-03-2018 CP478_RS10370 89239780e591de40fac833eafc49173f 320 SUPERFAMILY SSF51971 6 202 1.12E-28 T 28-03-2018 CP478_RS10370 89239780e591de40fac833eafc49173f 320 Pfam PF01266 FAD dependent oxidoreductase 8 315 3.2E-33 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CP478_RS16795 f0e77e63f34dec1809e92ca06fcc0104 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 9 126 18.81 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CP478_RS16795 f0e77e63f34dec1809e92ca06fcc0104 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 120 2.2E-26 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CP478_RS02235 d093265edb5aec575b3ae3f53b0e57d0 498 SUPERFAMILY SSF55486 46 262 1.05E-19 T 28-03-2018 CP478_RS09305 9972e659bd725b9d8b4e2c1057b9ad6f 394 Gene3D G3DSA:1.10.287.1060 58 139 6.8E-6 T 28-03-2018 CP478_RS09305 9972e659bd725b9d8b4e2c1057b9ad6f 394 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 312 388 5.9E-11 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS09305 9972e659bd725b9d8b4e2c1057b9ad6f 394 SUPERFAMILY SSF140459 38 211 1.99E-65 T 28-03-2018 CP478_RS09305 9972e659bd725b9d8b4e2c1057b9ad6f 394 Pfam PF00823 PPE family 41 198 3.8E-63 T 28-03-2018 IPR000030 PPE family CP478_RS06370 4f8ac8e8e0888a9c7785dccac218614e 94 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 20.266 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS06370 4f8ac8e8e0888a9c7785dccac218614e 94 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 90 5.9E-27 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS06370 4f8ac8e8e0888a9c7785dccac218614e 94 SUPERFAMILY SSF55248 3 92 1.96E-28 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS06370 4f8ac8e8e0888a9c7785dccac218614e 94 Gene3D G3DSA:3.30.1360.20 2 94 1.1E-27 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CP478_RS17375 48b76aa83151fd0d349bb875c79406c7 495 SUPERFAMILY SSF75304 8 487 1.31E-112 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS17375 48b76aa83151fd0d349bb875c79406c7 495 Pfam PF01425 Amidase 32 476 1.7E-130 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS17375 48b76aa83151fd0d349bb875c79406c7 495 Gene3D G3DSA:3.90.1300.10 9 491 1.4E-118 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS06530 dee28e7e8603d9c578d8d41f4edc991c 275 Gene3D G3DSA:3.40.50.1820 34 274 7.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06530 dee28e7e8603d9c578d8d41f4edc991c 275 SUPERFAMILY SSF53474 46 233 1.02E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12900 3a3cc7eb5f8b989bc589add9dd975458 113 SUPERFAMILY SSF53927 15 85 8.65E-7 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CP478_RS12900 3a3cc7eb5f8b989bc589add9dd975458 113 Gene3D G3DSA:3.40.140.10 10 112 9.1E-5 T 28-03-2018 CP478_RS11240 0f03194bee31b412bb18302a65b8aad4 1194 Pfam PF02514 CobN/Magnesium Chelatase 104 1176 0.0 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 CP478_RS11240 0f03194bee31b412bb18302a65b8aad4 1194 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 37 1189 0.0 T 28-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 CP478_RS16330 61d76a4aaea266062a9b0e524ae5b9ac 198 SUPERFAMILY SSF52016 1 184 6.08E-49 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CP478_RS16330 61d76a4aaea266062a9b0e524ae5b9ac 198 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 8.7E-50 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CP478_RS16330 61d76a4aaea266062a9b0e524ae5b9ac 198 Gene3D G3DSA:3.20.19.10 1 168 7.5E-41 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CP478_RS16330 61d76a4aaea266062a9b0e524ae5b9ac 198 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 36.816 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CP478_RS16330 61d76a4aaea266062a9b0e524ae5b9ac 198 Pfam PF00694 Aconitase C-terminal domain 1 116 6.0E-23 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CP478_RS15990 4081234c24bed4c606d9b40c62b9770a 207 Pfam PF02620 Uncharacterized ACR, COG1399 84 193 3.9E-28 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CP478_RS14825 6f0a22fc8b96af5558b05a54fbb86e2b 142 Gene3D G3DSA:3.30.1330.40 2 121 1.7E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CP478_RS14825 6f0a22fc8b96af5558b05a54fbb86e2b 142 SUPERFAMILY SSF55298 5 122 9.42E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CP478_RS14825 6f0a22fc8b96af5558b05a54fbb86e2b 142 Pfam PF01042 Endoribonuclease L-PSP 13 120 1.0E-26 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 Gene3D G3DSA:1.10.10.60 1 73 1.5E-19 T 28-03-2018 CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 SUPERFAMILY SSF46689 23 86 4.85E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 SUPERFAMILY SSF48498 97 213 2.1E-38 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 4.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 Gene3D G3DSA:1.10.357.10 74 216 8.4E-15 T 28-03-2018 CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS21075 320f94fd9da18d44dc339252a9c840e3 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS15455 dc18c5bb48471361156b655a66fdb1db 294 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 36 272 7.1E-24 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CP478_RS02075 aabfed0d635b7deca3748471769951bc 140 SMART SM00450 8 124 5.9E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS02075 aabfed0d635b7deca3748471769951bc 140 SUPERFAMILY SSF52821 5 139 5.5E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS02075 aabfed0d635b7deca3748471769951bc 140 Pfam PF00581 Rhodanese-like domain 9 116 9.5E-6 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS02075 aabfed0d635b7deca3748471769951bc 140 Gene3D G3DSA:3.40.250.10 1 140 3.1E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 SUPERFAMILY SSF50129 32 212 6.09E-54 T 28-03-2018 IPR011032 GroES-like CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 SUPERFAMILY SSF50129 330 379 1.98E-6 T 28-03-2018 IPR011032 GroES-like CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 Gene3D G3DSA:3.40.50.720 209 322 5.1E-20 T 28-03-2018 CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 48 174 1.7E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 Gene3D G3DSA:3.90.180.10 27 208 3.7E-45 T 28-03-2018 CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 80 94 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 SUPERFAMILY SSF51735 178 344 5.26E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 Pfam PF00107 Zinc-binding dehydrogenase 216 330 2.4E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CP478_RS00890 3a29cc5bec14a1bf6ab425de06b3000e 383 SMART SM00829 24 373 5.2E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CP478_RS03105 dcf6925cc7097f66ca6c58f74e13b60b 252 Gene3D G3DSA:3.10.20.30 4 79 3.3E-5 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS03105 dcf6925cc7097f66ca6c58f74e13b60b 252 Pfam PF14451 Mut7-C ubiquitin 4 82 8.7E-32 T 28-03-2018 IPR027798 Ubiquitin Mut7-C domain CP478_RS03105 dcf6925cc7097f66ca6c58f74e13b60b 252 Pfam PF01927 Mut7-C RNAse domain 97 239 7.9E-45 T 28-03-2018 IPR002782 Mut7-C RNAse domain CP478_RS05715 2119753275015ff2563254ee89f063a6 341 Gene3D G3DSA:2.40.10.10 228 330 5.8E-15 T 28-03-2018 CP478_RS05715 2119753275015ff2563254ee89f063a6 341 Gene3D G3DSA:2.40.10.10 116 227 1.2E-9 T 28-03-2018 CP478_RS05715 2119753275015ff2563254ee89f063a6 341 SUPERFAMILY SSF50494 121 334 2.24E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS05715 2119753275015ff2563254ee89f063a6 341 Pfam PF13365 Trypsin-like peptidase domain 145 293 1.1E-17 T 28-03-2018 CP478_RS02255 47158876b9812d3d5eb35f43cee0eab2 547 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 82 505 3.9E-207 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CP478_RS02255 47158876b9812d3d5eb35f43cee0eab2 547 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 81 508 55.564 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CP478_RS02255 47158876b9812d3d5eb35f43cee0eab2 547 Pfam PF01964 Radical SAM ThiC family 82 502 6.3E-199 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CP478_RS02255 47158876b9812d3d5eb35f43cee0eab2 547 Pfam PF13667 ThiC-associated domain 22 72 5.2E-9 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CP478_RS05000 aff142b0ffb1153642acb43cb23b33fd 593 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 61 511 3.5E-182 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CP478_RS05000 aff142b0ffb1153642acb43cb23b33fd 593 ProSitePatterns PS01303 BCCT family of transporters signature. 327 336 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CP478_RS05000 aff142b0ffb1153642acb43cb23b33fd 593 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 23 508 1.1E-180 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CP478_RS05645 b20903d66a5ffecfa3f9aab3c7f08e86 571 Pfam PF03814 Potassium-transporting ATPase A subunit 11 568 1.7E-237 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CP478_RS05645 b20903d66a5ffecfa3f9aab3c7f08e86 571 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 570 34.385 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CP478_RS05645 b20903d66a5ffecfa3f9aab3c7f08e86 571 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 571 0.0 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CP478_RS05645 b20903d66a5ffecfa3f9aab3c7f08e86 571 PIRSF PIRSF001294 1 571 1.0E-240 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CP478_RS19430 841516bc06159c2cfeae249b90af1199 289 Pfam PF04480 Protein of unknown function (DUF559) 217 266 2.7E-4 T 28-03-2018 IPR007569 Domain of unknown function DUF559 CP478_RS19430 841516bc06159c2cfeae249b90af1199 289 Gene3D G3DSA:3.40.960.10 181 287 3.2E-12 T 28-03-2018 CP478_RS19430 841516bc06159c2cfeae249b90af1199 289 SUPERFAMILY SSF52980 178 278 9.12E-9 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 Gene3D G3DSA:3.40.50.720 2 275 3.3E-59 T 28-03-2018 CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 Pfam PF00106 short chain dehydrogenase 9 197 1.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 SUPERFAMILY SSF51735 4 244 3.33E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS04645 11bd2f9b8352157f75c8d8179c40526b 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 Pfam PF00743 Flavin-binding monooxygenase-like 80 346 8.0E-12 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 Gene3D G3DSA:3.40.50.720 2 19 0.23 T 28-03-2018 CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 57 9.8E-8 T 28-03-2018 CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 SUPERFAMILY SSF51905 1 388 2.46E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 Gene3D G3DSA:3.50.50.60 166 463 1.3E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21070 74e918a299b3d31aba505e7f7fec090c 489 Gene3D G3DSA:3.50.50.60 20 165 2.8E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 6.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 6.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 6.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.9E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 SUPERFAMILY SSF51735 4 263 4.9E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 1.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 1.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 205 3.4E-5 T 28-03-2018 CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 Pfam PF00106 short chain dehydrogenase 7 214 2.5E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS19390 4f567f738cbb648e0ad65b4c115b4eb1 304 Gene3D G3DSA:3.40.50.720 6 262 6.0E-63 T 28-03-2018 CP478_RS17610 2e3c896b2483023baad2b3cce0eb619b 407 Gene3D G3DSA:2.140.10.10 3 180 6.6E-8 T 28-03-2018 CP478_RS17610 2e3c896b2483023baad2b3cce0eb619b 407 SUPERFAMILY SSF50998 217 387 3.53E-8 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CP478_RS17610 2e3c896b2483023baad2b3cce0eb619b 407 SUPERFAMILY SSF50998 23 184 3.53E-8 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CP478_RS17610 2e3c896b2483023baad2b3cce0eb619b 407 Gene3D G3DSA:2.130.10.10 254 406 4.5E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS20625 e7a11487198067449354bab2cb2ebfce 415 Pfam PF00144 Beta-lactamase 43 398 1.3E-68 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS20625 e7a11487198067449354bab2cb2ebfce 415 SUPERFAMILY SSF56601 33 390 3.92E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS20625 e7a11487198067449354bab2cb2ebfce 415 Gene3D G3DSA:3.40.710.10 15 415 9.1E-69 T 28-03-2018 CP478_RS03545 aa7ea2a38413b704156667bc3741e0b9 51 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 44 3.0E-16 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS18435 7412caf682f1ae4e4351f2a3db6c2c2c 154 PIRSF PIRSF029256 1 154 9.2E-58 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CP478_RS18435 7412caf682f1ae4e4351f2a3db6c2c2c 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 29.77 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CP478_RS18435 7412caf682f1ae4e4351f2a3db6c2c2c 154 Pfam PF00588 SpoU rRNA Methylase family 2 142 8.1E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CP478_RS18435 7412caf682f1ae4e4351f2a3db6c2c2c 154 SUPERFAMILY SSF75217 2 152 4.19E-41 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS18435 7412caf682f1ae4e4351f2a3db6c2c2c 154 Gene3D G3DSA:3.40.1280.10 1 154 2.0E-35 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS20805 90c98a521207a63e71a4c30dbc45bedf 284 Pfam PF01744 GLTT repeat (6 copies) 93 120 6.7E-6 T 28-03-2018 IPR008164 Repeat of unknown function XGLTT CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 Pfam PF00698 Acyl transferase domain 7 283 3.2E-22 T 28-03-2018 IPR014043 Acyl transferase CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 SUPERFAMILY SSF52151 183 300 9.16E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 SUPERFAMILY SSF52151 2 121 9.16E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 SUPERFAMILY SSF55048 129 183 9.29E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 2.5E-15 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 Gene3D G3DSA:3.40.366.10 164 300 6.8E-28 T 28-03-2018 CP478_RS12205 f427429e465b66559ca82cee4c4110f0 302 Gene3D G3DSA:3.40.366.10 1 163 1.1E-30 T 28-03-2018 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 SUPERFAMILY SSF56214 3 128 1.83E-22 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 129 21.252 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 128 1.0E-4 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 Gene3D G3DSA:3.90.470.20 2 130 2.2E-31 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 104 1.6E-18 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS13820 24c312dc64277c96cd6bb3d1008d429c 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 129 1.3E-40 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CP478_RS17835 1b5efed4da753f0078a028229f86309d 495 PIRSF PIRSF006060 4 493 2.5E-89 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS17835 1b5efed4da753f0078a028229f86309d 495 Pfam PF13520 Amino acid permease 28 453 3.2E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS11935 2d0ac75d4b8ed7da4e3803cc276e2cdc 429 Pfam PF00355 Rieske [2Fe-2S] domain 343 400 6.9E-9 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS11935 2d0ac75d4b8ed7da4e3803cc276e2cdc 429 Gene3D G3DSA:2.102.10.10 247 429 3.0E-39 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS11935 2d0ac75d4b8ed7da4e3803cc276e2cdc 429 SUPERFAMILY SSF50022 338 427 1.44E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 373 8.3E-192 T 28-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 Gene3D G3DSA:3.20.20.70 13 374 1.1E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 302 2.5E-31 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 SMART SM01240 15 374 4.5E-13 T 28-03-2018 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 SUPERFAMILY SSF51412 116 371 6.15E-57 T 28-03-2018 CP478_RS18665 689699bde62a55be1d4b0a1dbe9c22e5 375 SUPERFAMILY SSF51412 6 75 6.15E-57 T 28-03-2018 CP478_RS16390 3fef2d9298c848920d17bfef4c53b7e8 480 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 55 2.5E-7 T 28-03-2018 CP478_RS16390 3fef2d9298c848920d17bfef4c53b7e8 480 Gene3D G3DSA:3.50.50.60 1 463 2.4E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16390 3fef2d9298c848920d17bfef4c53b7e8 480 SUPERFAMILY SSF51905 2 292 1.49E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16390 3fef2d9298c848920d17bfef4c53b7e8 480 SUPERFAMILY SSF51905 433 463 1.49E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS21430 b1807e79c3c6c930e0faad2ca84b45df 120 Pfam PF01809 Haemolytic domain 23 86 1.6E-26 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CP478_RS21430 b1807e79c3c6c930e0faad2ca84b45df 120 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 33 86 2.0E-26 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CP478_RS21430 b1807e79c3c6c930e0faad2ca84b45df 120 SMART SM01234 19 86 3.1E-34 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CP478_RS21430 b1807e79c3c6c930e0faad2ca84b45df 120 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 23 90 6.8E-28 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CP478_RS21430 b1807e79c3c6c930e0faad2ca84b45df 120 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 19 87 23.072 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 Gene3D G3DSA:3.50.50.60 392 563 2.3E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 Gene3D G3DSA:3.50.50.60 20 334 2.3E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 Pfam PF00890 FAD binding domain 23 547 2.0E-112 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 PIRSF PIRSF036654 16 565 0.0 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 SUPERFAMILY SSF51905 502 564 6.2E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04265 d6c016246c37eb0c29ba0b5d2bbb4133 566 SUPERFAMILY SSF51905 20 293 6.2E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.5E-54 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.639 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.4E-46 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 Gene3D G3DSA:3.90.1170.10 2 138 4.9E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 SUPERFAMILY SSF54686 1 135 4.32E-55 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CP478_RS03840 e116603d0e5910b4dbfeadd9456ae188 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 SUPERFAMILY SSF56519 130 312 1.16E-29 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 SUPERFAMILY SSF56601 313 666 1.25E-93 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 Pfam PF03717 Penicillin-binding Protein dimerisation domain 131 294 2.2E-9 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 Pfam PF00905 Penicillin binding protein transpeptidase domain 339 654 3.3E-89 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 Gene3D G3DSA:3.90.1310.10 100 309 2.6E-31 T 28-03-2018 CP478_RS11765 215a96ecfb73a8aa5016e0ea03366354 679 Gene3D G3DSA:3.40.710.10 310 664 4.0E-87 T 28-03-2018 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 Gene3D G3DSA:3.30.70.920 85 169 2.0E-18 T 28-03-2018 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 Pfam PF13412 Winged helix-turn-helix DNA-binding 32 79 1.8E-15 T 28-03-2018 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 Gene3D G3DSA:1.10.10.10 28 83 6.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 Pfam PF01037 Lrp/AsnC ligand binding domain 99 171 2.7E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 SUPERFAMILY SSF54909 92 173 5.77E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 SUPERFAMILY SSF46785 32 91 2.77E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 SMART SM00344 32 141 1.7E-48 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 48 1.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 59 78 1.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS15220 7b78a5548ad96aa8d44a25d49aa33c66 179 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 59 1.7E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CP478_RS08870 7da9a105784add48bb2ec2827c82901b 346 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 326 2.6E-100 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CP478_RS08870 7da9a105784add48bb2ec2827c82901b 346 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 219 1.1E-58 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CP478_RS08870 7da9a105784add48bb2ec2827c82901b 346 PIRSF PIRSF000267 1 340 3.0E-100 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CP478_RS13975 aed8269b5b67d537fcb6aa270ba8811b 131 Gene3D G3DSA:3.40.50.1010 1 130 2.5E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13975 aed8269b5b67d537fcb6aa270ba8811b 131 SUPERFAMILY SSF88723 1 125 3.36E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13975 aed8269b5b67d537fcb6aa270ba8811b 131 Pfam PF01850 PIN domain 2 125 5.9E-17 T 28-03-2018 IPR002716 PIN domain CP478_RS13975 aed8269b5b67d537fcb6aa270ba8811b 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 130 13.636 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 SUPERFAMILY SSF53474 40 296 6.26E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 Pfam PF12697 Alpha/beta hydrolase family 52 289 4.4E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS00250 17f13d35b9746f901ff8f18dff9d02c8 298 Gene3D G3DSA:3.40.50.1820 6 298 5.0E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS19055 b0df3d09d19a6a33d2295691c4a0227d 512 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 109 281 1.2E-42 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS19055 b0df3d09d19a6a33d2295691c4a0227d 512 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 379 463 2.9E-11 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CP478_RS19055 b0df3d09d19a6a33d2295691c4a0227d 512 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 109 280 8.3E-28 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS01280 cce9047bbe77accbfff87bd33d00796c 57 ProDom PD383784 PRECURSOR SIGNAL SECRETED MB0242C RV0236.1/MT0250 ML2569.1 3 56 9.0E-24 T 28-03-2018 CP478_RS01280 cce9047bbe77accbfff87bd33d00796c 57 Pfam PF11021 Protein of unknown function (DUF2613) 3 56 1.2E-21 T 28-03-2018 IPR022566 Protein of unknown function DUF2613 CP478_RS18370 b9e532515fc34eebc2108d024f220237 86 Gene3D G3DSA:3.30.43.10 25 86 6.5E-5 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CP478_RS09855 d3fa9265b0357a01779f73a3e5b89009 118 Pfam PF05305 Protein of unknown function (DUF732) 19 113 2.5E-24 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS20925 b47ebcb0b55636cdc0627d110c9a67da 160 Pfam PF11196 Protein of unknown function (DUF2834) 41 147 1.3E-29 T 28-03-2018 IPR021362 Protein of unknown function DUF2834 CP478_RS04980 ee43a09576750c3345c9044af207027f 502 Pfam PF03055 Retinal pigment epithelial membrane protein 27 483 3.0E-92 T 28-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CP478_RS02220 1239ae9caace39115e98623cbfc63c74 252 SUPERFAMILY SSF110399 5 242 2.09E-81 T 28-03-2018 CP478_RS02220 1239ae9caace39115e98623cbfc63c74 252 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 5.1E-107 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CP478_RS02220 1239ae9caace39115e98623cbfc63c74 252 Hamap MF_00443 Thiazole synthase [thiG]. 5 252 40.756 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CP478_RS02220 1239ae9caace39115e98623cbfc63c74 252 Gene3D G3DSA:3.20.20.70 3 252 2.2E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 25 33 2.8E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 94 108 2.8E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 62 2.8E-12 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 1 282 1.0E-113 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 PIRSF PIRSF005539 1 286 1.3E-93 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 SUPERFAMILY SSF53474 5 281 8.4E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 Pfam PF00561 alpha/beta hydrolase fold 24 270 2.7E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS04585 7cc7f78ce9277c235535ab3b186f22e8 286 Gene3D G3DSA:3.40.50.1820 2 284 8.1E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS02450 550c05448434f5337ef5211b3a85997d 163 Pfam PF05610 Protein of unknown function (DUF779) 16 113 2.1E-44 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CP478_RS02450 550c05448434f5337ef5211b3a85997d 163 PIRSF PIRSF009151 1 128 8.3E-66 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CP478_RS20180 0141526bff1e9940777c1056a6c56dcd 330 Pfam PF01944 Stage II sporulation protein M 108 281 3.1E-35 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CP478_RS11450 4e5b02eb5e9333298ac4f95fa1ddc4ef 84 Gene3D G3DSA:1.10.1220.10 1 84 9.4E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS14390 4f92dbc6373d56b1d92cac8d90c2919a 413 Gene3D G3DSA:3.40.50.1820 143 397 6.2E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14390 4f92dbc6373d56b1d92cac8d90c2919a 413 SUPERFAMILY SSF53474 171 380 9.02E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS15440 6568a042ba100d1c015820b6c92eb06e 812 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 9 690 1.0E-126 T 28-03-2018 IPR013408 CRISPR-associated protein Csm1 CP478_RS15440 6568a042ba100d1c015820b6c92eb06e 812 SUPERFAMILY SSF109604 7 112 1.75E-5 T 28-03-2018 CP478_RS15440 6568a042ba100d1c015820b6c92eb06e 812 Gene3D G3DSA:1.10.3210.10 2 195 7.3E-10 T 28-03-2018 CP478_RS00070 a115baa759ff07bfcff4b8e2f65fcd20 93 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 93 21.642 T 28-03-2018 IPR009619 Cell division protein CrgA CP478_RS00070 a115baa759ff07bfcff4b8e2f65fcd20 93 Pfam PF06781 Cell division protein CrgA 1 93 2.1E-29 T 28-03-2018 IPR009619 Cell division protein CrgA CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 SUPERFAMILY SSF51735 100 281 9.22E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 6 527 2.1E-207 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.9E-61 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 313 1.3E-37 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 SUPERFAMILY SSF52283 4 134 1.29E-38 T 28-03-2018 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Gene3D G3DSA:3.40.50.720 113 284 3.2E-58 T 28-03-2018 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Gene3D G3DSA:3.30.1330.90 315 449 4.0E-29 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Gene3D G3DSA:3.30.70.260 450 525 7.9E-12 T 28-03-2018 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 SUPERFAMILY SSF55021 453 525 1.12E-13 T 28-03-2018 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Gene3D G3DSA:3.40.50.720 4 112 2.8E-35 T 28-03-2018 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 SUPERFAMILY SSF143548 320 449 2.12E-31 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CP478_RS16385 d65af7225cad607e4e79b19c8bdb80f8 528 Pfam PF01842 ACT domain 456 515 2.4E-8 T 28-03-2018 IPR002912 ACT domain CP478_RS21190 61185b7f6f9e0c52f5a1302079977b6b 666 Gene3D G3DSA:3.40.50.300 414 665 2.9E-27 T 28-03-2018 CP478_RS21190 61185b7f6f9e0c52f5a1302079977b6b 666 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 419 569 8.4E-10 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS21190 61185b7f6f9e0c52f5a1302079977b6b 666 SUPERFAMILY SSF52540 418 637 4.32E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS21185 55b42d0261b0e8f603b7ac298676ca34 95 Pfam PF06013 Proteins of 100 residues with WXG 5 87 3.2E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21185 55b42d0261b0e8f603b7ac298676ca34 95 SUPERFAMILY SSF140453 5 94 1.83E-21 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21185 55b42d0261b0e8f603b7ac298676ca34 95 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 89 1.3E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21185 55b42d0261b0e8f603b7ac298676ca34 95 Gene3D G3DSA:1.10.287.1060 1 95 1.3E-15 T 28-03-2018 CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 174 3.1E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 351 1.6E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 17 358 40.906 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 SUPERFAMILY SSF56042 182 350 6.88E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 Gene3D G3DSA:3.30.1330.10 47 171 3.8E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 SUPERFAMILY SSF55326 17 179 3.74E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 Gene3D G3DSA:3.90.650.10 181 358 6.3E-55 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CP478_RS04390 d6c64f7ddcdc656d41b6593443de2aba 364 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 17 347 8.4E-144 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CP478_RS08705 93982cd66fe628826dd14713fe61bb4b 79 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 18 75 4.0E-29 T 28-03-2018 CP478_RS06550 dece37e8b7b39a9f4a1c5151300715f3 99 SUPERFAMILY SSF140459 8 84 6.02E-24 T 28-03-2018 CP478_RS06550 dece37e8b7b39a9f4a1c5151300715f3 99 Pfam PF00934 PE family 2 93 1.7E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS03935 3f94c31ef4ceb22a15634f5ace820004 218 Gene3D G3DSA:3.40.225.10 4 212 1.2E-52 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CP478_RS03935 3f94c31ef4ceb22a15634f5ace820004 218 SUPERFAMILY SSF53639 11 211 3.14E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CP478_RS03935 3f94c31ef4ceb22a15634f5ace820004 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 186 3.3E-45 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CP478_RS03935 3f94c31ef4ceb22a15634f5ace820004 218 SMART SM01007 9 187 9.6E-54 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CP478_RS13260 306e0ba92ab36ca4e357cae6886a0a5c 64 Gene3D G3DSA:1.10.10.10 1 63 2.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06970 2bbaf1d75e50380491f0be8a42bd6cb8 185 ProDom PD103646 LIPOPROTEIN LPRB MEMBRANE PRECURSOR PALMITATE SIGNAL 7 185 3.0E-101 T 28-03-2018 CP478_RS06970 2bbaf1d75e50380491f0be8a42bd6cb8 185 Pfam PF12079 Protein of unknown function (DUF3558) 21 183 8.9E-38 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CP478_RS14290 4827a105d3b1535d89dc82e14e033a02 580 Gene3D G3DSA:3.40.50.1820 265 532 2.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14290 4827a105d3b1535d89dc82e14e033a02 580 Pfam PF00823 PPE family 5 162 2.5E-59 T 28-03-2018 IPR000030 PPE family CP478_RS14290 4827a105d3b1535d89dc82e14e033a02 580 Pfam PF08237 PE-PPE domain 300 525 1.5E-77 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS14290 4827a105d3b1535d89dc82e14e033a02 580 Gene3D G3DSA:1.10.287.1060 22 111 4.9E-6 T 28-03-2018 CP478_RS14290 4827a105d3b1535d89dc82e14e033a02 580 SUPERFAMILY SSF140459 2 170 2.25E-58 T 28-03-2018 CP478_RS12380 48af9c00e9bcb8d92f276b77511dcede 301 SUPERFAMILY SSF51695 30 300 1.18E-46 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS12380 48af9c00e9bcb8d92f276b77511dcede 301 Gene3D G3DSA:3.20.20.190 25 301 7.8E-44 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS12380 48af9c00e9bcb8d92f276b77511dcede 301 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 36 294 2.3E-19 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CP478_RS13545 cd8d20a0258eaafe5bcd2c24bd99c762 161 SUPERFAMILY SSF50249 1 150 8.23E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CP478_RS13545 cd8d20a0258eaafe5bcd2c24bd99c762 161 PIRSF PIRSF002070 1 150 6.3E-29 T 28-03-2018 CP478_RS13545 cd8d20a0258eaafe5bcd2c24bd99c762 161 Pfam PF00436 Single-strand binding protein family 1 96 5.2E-15 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CP478_RS13545 cd8d20a0258eaafe5bcd2c24bd99c762 161 Gene3D G3DSA:2.40.50.140 1 109 7.2E-26 T 28-03-2018 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 SMART SM00387 355 466 3.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 312 2.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 SMART SM00304 176 238 3.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 8.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 8.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 8.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 8.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 Gene3D G3DSA:1.10.287.130 229 308 3.0E-16 T 28-03-2018 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 465 2.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 SUPERFAMILY SSF55874 301 466 7.33E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 Gene3D G3DSA:3.30.565.10 315 474 1.6E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 SMART SM00388 246 312 1.3E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 Pfam PF00672 HAMP domain 177 233 7.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CP478_RS20555 c038d2485f53f7ec29531c5e45f314a0 475 SUPERFAMILY SSF47384 231 313 2.16E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CP478_RS12350 1e701c8e874b0aac65af86351a476db4 99 Pfam PF10905 Protein of unknown function (DUF2695) 39 91 1.8E-24 T 28-03-2018 IPR024248 Protein of unknown function DUF2695 CP478_RS12350 1e701c8e874b0aac65af86351a476db4 99 ProDom PD067169 MB2294 RV2271/MT2332 1 99 4.0E-54 T 28-03-2018 IPR024248 Protein of unknown function DUF2695 CP478_RS12350 1e701c8e874b0aac65af86351a476db4 99 Gene3D G3DSA:3.40.190.10 5 77 8.7E-4 T 28-03-2018 CP478_RS04370 876bf0fdb96d386cf77bbd9f31ecff35 318 Gene3D G3DSA:3.60.21.10 1 278 1.7E-51 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS04370 876bf0fdb96d386cf77bbd9f31ecff35 318 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 14 266 37.41 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CP478_RS04370 876bf0fdb96d386cf77bbd9f31ecff35 318 Pfam PF00149 Calcineurin-like phosphoesterase 16 209 2.7E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CP478_RS04370 876bf0fdb96d386cf77bbd9f31ecff35 318 SUPERFAMILY SSF56300 12 264 2.19E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 1.9E-51 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 SUPERFAMILY SSF53067 104 313 2.2E-34 T 28-03-2018 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 Pfam PF00814 Glycoprotease family 29 312 3.5E-86 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 338 60.088 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 318 1.4E-113 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 SUPERFAMILY SSF53067 4 124 2.91E-23 T 28-03-2018 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 Gene3D G3DSA:3.30.420.40 145 295 8.8E-18 T 28-03-2018 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 Gene3D G3DSA:3.30.420.40 2 144 2.6E-31 T 28-03-2018 CP478_RS18710 1b7721311c3aab9107ce4a245ef82833 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 312 7.0E-87 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 SUPERFAMILY SSF55031 166 268 4.34E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 64 73 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 5 352 4.7E-156 T 28-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 Pfam PF01546 Peptidase family M20/M25/M40 65 352 2.3E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 SUPERFAMILY SSF53187 274 352 1.16E-45 T 28-03-2018 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 SUPERFAMILY SSF53187 7 178 1.16E-45 T 28-03-2018 CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 Pfam PF07687 Peptidase dimerisation domain 166 263 1.5E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS06590 88018de4294b1851f5386ea4cf694b36 354 Gene3D G3DSA:3.40.630.10 7 353 1.8E-45 T 28-03-2018 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 TIGRFAM TIGR00891 2A0112: MFS transporter, sialate:H+ symporter (SHS) family 2 388 1.9E-179 T 28-03-2018 IPR004742 Sialic acid transporter GO:0015144|GO:0016021|GO:0034219 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 ProSitePatterns PS00217 Sugar transport proteins signature 2. 109 134 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 Pfam PF00083 Sugar (and other) transporter 247 396 5.7E-14 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 SUPERFAMILY SSF103473 7 401 8.76E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 Gene3D G3DSA:1.20.1250.20 9 194 1.1E-31 T 28-03-2018 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 Gene3D G3DSA:1.20.1250.20 201 402 4.5E-20 T 28-03-2018 CP478_RS10355 ff451ba15c44c2f9209bbe0e41c2edc5 422 Pfam PF07690 Major Facilitator Superfamily 22 238 8.7E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 1.9E-139 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 3.2E-86 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.212 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 PIRSF PIRSF000099 2 438 9.7E-151 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 Gene3D G3DSA:3.40.50.1980 234 380 2.7E-60 T 28-03-2018 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 Pfam PF00815 Histidinol dehydrogenase 23 436 2.9E-154 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 Gene3D G3DSA:3.40.50.1980 28 233 5.0E-80 T 28-03-2018 CP478_RS08750 8c3a361849ed28e9e3a009bec98b7c29 438 SUPERFAMILY SSF53720 27 436 1.94E-72 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS14440 2d2350d2a2aba447de2f7f1a343fe3c5 225 PIRSF PIRSF007531 1 225 2.1E-86 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 CP478_RS14440 2d2350d2a2aba447de2f7f1a343fe3c5 225 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 23 208 3.6E-70 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 CP478_RS14440 2d2350d2a2aba447de2f7f1a343fe3c5 225 SUPERFAMILY SSF52540 20 208 3.39E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14440 2d2350d2a2aba447de2f7f1a343fe3c5 225 Gene3D G3DSA:3.40.50.300 21 208 2.5E-13 T 28-03-2018 CP478_RS17290 c54ad05c7e0795f07054f97e9b263d9f 531 Pfam PF00361 Proton-conducting membrane transporter 169 465 9.2E-70 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17290 c54ad05c7e0795f07054f97e9b263d9f 531 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 8 520 17.557 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CP478_RS17290 c54ad05c7e0795f07054f97e9b263d9f 531 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 142 520 3.2E-115 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CP478_RS20500 ae3f5f9e95240310c14d9bdbda3c6fa8 173 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 18 166 1.6E-50 T 28-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative CP478_RS18985 8ac8a714e787e2ceb3114aaffe64dda5 336 SUPERFAMILY SSF51569 6 262 1.61E-52 T 28-03-2018 CP478_RS18985 8ac8a714e787e2ceb3114aaffe64dda5 336 Gene3D G3DSA:3.20.20.70 3 248 5.2E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS18985 8ac8a714e787e2ceb3114aaffe64dda5 336 Pfam PF00682 HMGL-like 11 262 5.7E-39 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CP478_RS18985 8ac8a714e787e2ceb3114aaffe64dda5 336 Gene3D G3DSA:3.20.20.150 249 335 0.23 T 28-03-2018 CP478_RS01695 ac135b633abd2413faa0f0f450bb94e2 256 Gene3D G3DSA:3.20.20.190 3 255 3.6E-53 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS01695 ac135b633abd2413faa0f0f450bb94e2 256 SUPERFAMILY SSF51695 12 247 4.45E-52 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CP478_RS01695 ac135b633abd2413faa0f0f450bb94e2 256 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 241 5.5E-40 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CP478_RS05265 6fe0a3a73a265d7831c0908c0e3bee46 160 Gene3D G3DSA:3.40.50.2300 46 107 0.35 T 28-03-2018 CP478_RS18555 d0b079c9426d59cac30b76ffb94e9d5d 236 Gene3D G3DSA:3.40.50.1240 34 234 1.3E-25 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS18555 d0b079c9426d59cac30b76ffb94e9d5d 236 SMART SM00855 36 190 5.5E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS18555 d0b079c9426d59cac30b76ffb94e9d5d 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 37 229 2.4E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CP478_RS18555 d0b079c9426d59cac30b76ffb94e9d5d 236 SUPERFAMILY SSF53254 36 229 1.52E-27 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CP478_RS10850 42542c68a21ceca04cde88141ba8a71b 111 SUPERFAMILY SSF51735 2 33 1.38E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10850 42542c68a21ceca04cde88141ba8a71b 111 Gene3D G3DSA:3.40.50.720 1 77 1.4E-7 T 28-03-2018 CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Gene3D G3DSA:1.10.10.10 2 79 3.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SUPERFAMILY SSF46785 13 82 3.71E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SUPERFAMILY SSF48008 101 234 1.57E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Gene3D G3DSA:1.20.120.530 86 247 9.2E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Gene3D G3DSA:1.20.120.530 343 490 4.5E-13 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 2.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Pfam PF00392 Bacterial regulatory proteins, gntR family 268 327 1.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SUPERFAMILY SSF48008 355 489 1.57E-14 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SMART SM00895 103 227 2.0E-14 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SMART SM00895 357 484 7.5E-11 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Pfam PF07729 FCD domain 103 226 6.0E-17 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Pfam PF07729 FCD domain 357 483 1.1E-14 T 28-03-2018 IPR011711 GntR, C-terminal CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SMART SM00345 17 78 1.7E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SMART SM00345 271 332 0.38 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 Gene3D G3DSA:1.10.10.10 255 342 1.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16745 0ff44f9bd789fd1133a9a1dcefe0b595 490 SUPERFAMILY SSF46785 264 336 4.95E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 Gene3D G3DSA:1.10.357.10 57 190 2.5E-18 T 28-03-2018 CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 Gene3D G3DSA:1.10.10.60 2 56 2.7E-19 T 28-03-2018 CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 SUPERFAMILY SSF46689 3 74 3.39E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 SUPERFAMILY SSF48498 79 187 7.56E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS05580 09db859e121b0b6fae2b10a781c7e41a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 54 4.8E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Gene3D G3DSA:3.30.70.20 200 237 5.9E-18 T 28-03-2018 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 489 1.9E-224 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 360 441 1.0E-27 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Pfam PF13247 4Fe-4S dicluster domain 177 272 3.3E-36 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 SUPERFAMILY SSF54862 1 471 2.62E-156 T 28-03-2018 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Gene3D G3DSA:3.30.70.20 5 199 4.5E-28 T 28-03-2018 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Gene3D G3DSA:3.30.70.20 238 369 1.4E-26 T 28-03-2018 CP478_RS06385 1f12f106e942489199bbcf245fd10f6f 558 Gene3D G3DSA:1.10.3650.10 370 439 5.8E-29 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 Gene3D G3DSA:3.40.50.720 304 389 2.0E-9 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 Gene3D G3DSA:3.40.50.720 6 303 6.7E-38 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 SUPERFAMILY SSF54373 259 330 2.55E-24 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 Pfam PF03275 UDP-galactopyranose mutase 156 366 1.3E-79 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 81 5.8E-18 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 SUPERFAMILY SSF51971 8 278 3.18E-46 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 SUPERFAMILY SSF51971 351 384 3.18E-46 T 28-03-2018 CP478_RS20800 1bd7a5c979c1daa8b0423b18de1f3d65 399 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 8 384 2.1E-101 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CP478_RS06765 764ba04c9b4ca814fb6477049b0afa84 468 Gene3D G3DSA:3.40.190.10 149 466 1.8E-40 T 28-03-2018 CP478_RS06765 764ba04c9b4ca814fb6477049b0afa84 468 SUPERFAMILY SSF53850 34 289 4.24E-59 T 28-03-2018 CP478_RS06765 764ba04c9b4ca814fb6477049b0afa84 468 SUPERFAMILY SSF53850 331 439 4.24E-59 T 28-03-2018 CP478_RS06765 764ba04c9b4ca814fb6477049b0afa84 468 Pfam PF01547 Bacterial extracellular solute-binding protein 42 372 6.2E-31 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CP478_RS13635 9e358a7f2314216277fc6033d40ec433 73 Gene3D G3DSA:1.10.1220.10 1 49 2.1E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS02785 44ace8540fdd503a415421975f795b53 116 SUPERFAMILY SSF53335 3 108 2.05E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02785 44ace8540fdd503a415421975f795b53 116 Gene3D G3DSA:3.40.50.150 1 115 9.9E-20 T 28-03-2018 CP478_RS02785 44ace8540fdd503a415421975f795b53 116 Pfam PF08241 Methyltransferase domain 4 83 4.0E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS11880 b08ef8d97dc45476b404e2543340f02b 144 Gene3D G3DSA:3.30.530.20 3 144 1.2E-25 T 28-03-2018 IPR023393 START-like domain CP478_RS11880 b08ef8d97dc45476b404e2543340f02b 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 143 4.3E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS11880 b08ef8d97dc45476b404e2543340f02b 144 SUPERFAMILY SSF55961 4 144 5.71E-32 T 28-03-2018 CP478_RS09480 35cb71ab0dc72b39c8da7b0aa67d98b7 395 Gene3D G3DSA:1.20.1250.20 197 395 4.2E-27 T 28-03-2018 CP478_RS09480 35cb71ab0dc72b39c8da7b0aa67d98b7 395 SUPERFAMILY SSF103473 6 388 9.68E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS09480 35cb71ab0dc72b39c8da7b0aa67d98b7 395 Pfam PF07690 Major Facilitator Superfamily 14 346 3.8E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS09480 35cb71ab0dc72b39c8da7b0aa67d98b7 395 Gene3D G3DSA:1.20.1250.20 2 193 1.4E-19 T 28-03-2018 CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 43 320 5.0E-11 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 SUPERFAMILY SSF51735 106 289 1.14E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 288 1.2E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 Gene3D G3DSA:3.40.50.720 121 291 6.2E-50 T 28-03-2018 CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 SUPERFAMILY SSF52283 4 136 2.98E-16 T 28-03-2018 CP478_RS03940 6b37bdb9d869e4e1a12563515deee636 326 Gene3D G3DSA:3.40.50.720 3 120 3.2E-20 T 28-03-2018 CP478_RS16190 7f102049ac70c75a6f6b6f8058c2c29a 406 Pfam PF03773 Predicted permease 18 329 1.1E-85 T 28-03-2018 IPR005524 Predicted permease DUF318 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Gene3D G3DSA:2.30.38.10 358 431 3.6E-18 T 28-03-2018 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Gene3D G3DSA:3.40.50.980 9 187 3.2E-33 T 28-03-2018 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Gene3D G3DSA:3.30.300.30 432 537 2.8E-28 T 28-03-2018 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 1.0E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Gene3D G3DSA:3.40.50.980 188 346 3.9E-42 T 28-03-2018 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 Pfam PF00501 AMP-binding enzyme 27 437 7.1E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS05810 e7897fffc944b0a06c26ac2dd16b02b2 543 SUPERFAMILY SSF56801 9 533 2.62E-140 T 28-03-2018 CP478_RS17485 388f0a0aabc7759806f05d63d4e47dd6 205 SUPERFAMILY SSF51679 90 181 1.16E-10 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS17485 388f0a0aabc7759806f05d63d4e47dd6 205 Pfam PF00296 Luciferase-like monooxygenase 82 185 4.3E-12 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS17485 388f0a0aabc7759806f05d63d4e47dd6 205 Gene3D G3DSA:3.20.20.30 55 202 9.1E-9 T 28-03-2018 CP478_RS11085 8014ad9f0cc0c5a460d5da528da9fbb3 144 Gene3D G3DSA:2.60.40.790 3 141 8.0E-27 T 28-03-2018 IPR008978 HSP20-like chaperone CP478_RS11085 8014ad9f0cc0c5a460d5da528da9fbb3 144 Pfam PF00011 Hsp20/alpha crystallin family 47 140 7.7E-24 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CP478_RS11085 8014ad9f0cc0c5a460d5da528da9fbb3 144 SUPERFAMILY SSF49764 20 136 5.93E-26 T 28-03-2018 IPR008978 HSP20-like chaperone CP478_RS15575 ae30eafb41844009d2c67526bc9b84a5 207 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 18 207 4.5E-86 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CP478_RS15575 ae30eafb41844009d2c67526bc9b84a5 207 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 24 207 2.6E-57 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CP478_RS15575 ae30eafb41844009d2c67526bc9b84a5 207 SUPERFAMILY SSF52540 12 207 4.31E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS15575 ae30eafb41844009d2c67526bc9b84a5 207 Gene3D G3DSA:3.40.50.300 8 207 6.5E-60 T 28-03-2018 CP478_RS15575 ae30eafb41844009d2c67526bc9b84a5 207 PIRSF PIRSF015617 1 207 1.2E-67 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CP478_RS15610 9942a221397b079b3ee2e48400eefaec 372 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 67 348 9.9E-131 T 28-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CP478_RS15610 9942a221397b079b3ee2e48400eefaec 372 Pfam PF03824 High-affinity nickel-transport protein 64 353 7.6E-99 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CP478_RS20615 08b5a6d2070476696fe10a927007f1a2 194 Gene3D G3DSA:1.20.120.450 9 139 3.8E-11 T 28-03-2018 CP478_RS20615 08b5a6d2070476696fe10a927007f1a2 194 SUPERFAMILY SSF109854 11 138 1.74E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CP478_RS20615 08b5a6d2070476696fe10a927007f1a2 194 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 190 2.5E-31 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CP478_RS20615 08b5a6d2070476696fe10a927007f1a2 194 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 21 190 3.9E-40 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CP478_RS10565 a7fbfe74914f122d2ca6394c8749a791 109 Gene3D G3DSA:2.30.30.110 3 109 9.6E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS10565 a7fbfe74914f122d2ca6394c8749a791 109 SUPERFAMILY SSF50118 5 106 2.62E-18 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS10565 a7fbfe74914f122d2ca6394c8749a791 109 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 103 4.0E-14 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS18535 990d53e945e155faa184aa2932c464c5 102 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 12 63 8.3E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS18535 990d53e945e155faa184aa2932c464c5 102 Gene3D G3DSA:3.40.1620.10 12 102 3.2E-15 T 28-03-2018 CP478_RS18535 990d53e945e155faa184aa2932c464c5 102 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 14 49 1.5E-9 T 28-03-2018 CP478_RS18535 990d53e945e155faa184aa2932c464c5 102 SUPERFAMILY SSF143120 12 53 2.88E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS00435 787c94a8e1f4796ef8e6d89d363ca943 197 SUPERFAMILY SSF81301 4 145 6.38E-12 T 28-03-2018 CP478_RS00435 787c94a8e1f4796ef8e6d89d363ca943 197 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 16 182 4.4E-8 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CP478_RS15485 0c5137553a1616d551e28777a1366242 249 Gene3D G3DSA:3.90.226.10 1 230 1.6E-64 T 28-03-2018 CP478_RS15485 0c5137553a1616d551e28777a1366242 249 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 225 4.0E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS15485 0c5137553a1616d551e28777a1366242 249 SUPERFAMILY SSF52096 2 237 3.32E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS17500 fffa7dd9a495b7b82c192ec5b32930d6 472 SUPERFAMILY SSF55486 84 436 7.18E-110 T 28-03-2018 CP478_RS17500 fffa7dd9a495b7b82c192ec5b32930d6 472 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 85 436 2.1E-121 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CP478_RS17500 fffa7dd9a495b7b82c192ec5b32930d6 472 Pfam PF10103 Zincin-like metallopeptidase 85 433 1.1E-111 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 SUPERFAMILY SSF47973 1 149 3.01E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 PIRSF PIRSF002122 4 156 2.0E-57 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.5E-62 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 Gene3D G3DSA:1.10.455.10 6 156 1.1E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.763 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CP478_RS03690 16b97773a2cb5fe96821c3015351d940 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.9E-68 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CP478_RS19945 dfbbb64fa04321c3cc3afb901bd11a53 125 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 13 117 4.0E-26 T 28-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like CP478_RS19945 dfbbb64fa04321c3cc3afb901bd11a53 125 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 4.8E-9 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CP478_RS05840 71ddb3539e6ed991519c7ac49ee9ed03 139 ProDom PD076648 LIPOPROTEIN LPQV PALMITATE MEMBRANE PRECURSOR SIGNAL 1 120 6.0E-42 T 28-03-2018 IPR020377 Uncharacterised protein family LpqV CP478_RS05840 71ddb3539e6ed991519c7ac49ee9ed03 139 Pfam PF17301 Putative lipoprotein LpqV 33 139 3.0E-49 T 28-03-2018 IPR020377 Uncharacterised protein family LpqV CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 SUPERFAMILY SSF53790 1 201 1.96E-32 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 185 7.3E-34 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 Gene3D G3DSA:3.40.50.150 216 390 4.5E-22 T 28-03-2018 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 183 3.5E-16 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 PIRSF PIRSF036428 1 390 1.2E-136 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 Gene3D G3DSA:3.40.1010.10 1 111 7.0E-13 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 222 341 2.1E-25 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 SUPERFAMILY SSF53335 203 370 2.34E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11295 a295154ad5cca4334bfa51d154cce908 390 Gene3D G3DSA:3.30.950.10 112 208 9.6E-22 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CP478_RS03355 90f54fd4a135213f83aa7a46d0a4ab93 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 13.921 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03355 90f54fd4a135213f83aa7a46d0a4ab93 131 Gene3D G3DSA:3.40.50.1010 1 130 6.7E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03355 90f54fd4a135213f83aa7a46d0a4ab93 131 Pfam PF01850 PIN domain 1 124 1.0E-14 T 28-03-2018 IPR002716 PIN domain CP478_RS03355 90f54fd4a135213f83aa7a46d0a4ab93 131 SUPERFAMILY SSF88723 1 127 3.92E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS07470 8061df4771065dcf8d1cb457ec00b361 396 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 309 391 3.5E-17 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS07470 8061df4771065dcf8d1cb457ec00b361 396 SUPERFAMILY SSF140459 3 175 2.28E-61 T 28-03-2018 CP478_RS07470 8061df4771065dcf8d1cb457ec00b361 396 Gene3D G3DSA:1.10.287.1060 22 102 6.4E-4 T 28-03-2018 CP478_RS07470 8061df4771065dcf8d1cb457ec00b361 396 Pfam PF00823 PPE family 6 162 1.9E-59 T 28-03-2018 IPR000030 PPE family CP478_RS14445 486f9aefa7a24036e158ee374d8d55b4 218 Pfam PF09335 SNARE associated Golgi protein 32 161 1.3E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein CP478_RS17830 a48081c0bdeb3b6aaa46bb7bc272680c 416 Pfam PF00487 Fatty acid desaturase 138 369 1.6E-34 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 Gene3D G3DSA:3.90.470.20 31 116 1.2E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 SUPERFAMILY SSF56214 108 226 1.92E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 PRINTS PR01399 Enterobactin synthetase component D signature 151 167 1.4E-27 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 PRINTS PR01399 Enterobactin synthetase component D signature 76 94 1.4E-27 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 PRINTS PR01399 Enterobactin synthetase component D signature 46 66 1.4E-27 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 Gene3D G3DSA:3.90.470.20 117 219 1.5E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS15295 169e502a7ee6c2fc5a0186ba52c8d6be 227 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 110 184 6.8E-10 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CP478_RS08210 9be4d2357b6f182ec783190f6ccd27f3 211 SUPERFAMILY SSF53335 2 184 7.38E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS08210 9be4d2357b6f182ec783190f6ccd27f3 211 Pfam PF08241 Methyltransferase domain 8 123 2.8E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS08210 9be4d2357b6f182ec783190f6ccd27f3 211 Gene3D G3DSA:3.40.50.150 1 182 1.5E-34 T 28-03-2018 CP478_RS12230 97afdbcaabcaf20fb498d2f686d5fefe 271 SUPERFAMILY SSF52980 159 264 6.97E-8 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS12230 97afdbcaabcaf20fb498d2f686d5fefe 271 Gene3D G3DSA:3.40.960.10 133 270 6.1E-13 T 28-03-2018 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 Gene3D G3DSA:2.60.40.1730 7 197 5.1E-35 T 28-03-2018 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 856 1.2E-299 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 SUPERFAMILY SSF63737 6 196 5.1E-41 T 28-03-2018 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 Gene3D G3DSA:1.10.390.10 282 448 2.6E-49 T 28-03-2018 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 Pfam PF11838 ERAP1-like C-terminal domain 531 850 7.0E-56 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 Pfam PF01433 Peptidase family M1 domain 211 444 2.6E-60 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 SUPERFAMILY SSF55486 208 455 1.23E-77 T 28-03-2018 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 2.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 296 311 2.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 315 327 2.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 2.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS13485 d026077adde27ced25a694a0d6b44182 861 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 136 151 2.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CP478_RS18415 c4abac51af3369ba0f562a73642a6a36 193 SUPERFAMILY SSF52540 14 183 1.07E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18415 c4abac51af3369ba0f562a73642a6a36 193 Pfam PF03029 Conserved hypothetical ATP binding protein 18 185 9.0E-27 T 28-03-2018 IPR004130 GPN-loop GTPase CP478_RS18415 c4abac51af3369ba0f562a73642a6a36 193 Gene3D G3DSA:3.40.50.300 2 191 1.7E-21 T 28-03-2018 CP478_RS20435 a7b04b83c13a6bd200f8fed2803217ef 131 SUPERFAMILY SSF51905 10 130 3.11E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20435 a7b04b83c13a6bd200f8fed2803217ef 131 Gene3D G3DSA:3.50.50.60 8 95 3.2E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20435 a7b04b83c13a6bd200f8fed2803217ef 131 Gene3D G3DSA:3.50.50.60 96 130 0.0088 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS04365 52f876225a5814a590bcbe09e42ca9d3 209 PIRSF PIRSF026622 1 204 8.5E-84 T 28-03-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type CP478_RS04365 52f876225a5814a590bcbe09e42ca9d3 209 Pfam PF02517 CAAX protease self-immunity 96 189 6.5E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CP478_RS05845 0e550ae530901470bf94a36f54d08e8b 188 SUPERFAMILY SSF51182 23 184 2.97E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS05845 0e550ae530901470bf94a36f54d08e8b 188 Gene3D G3DSA:2.60.120.10 5 187 2.0E-33 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS05845 0e550ae530901470bf94a36f54d08e8b 188 Pfam PF05995 Cysteine dioxygenase type I 55 114 1.2E-11 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CP478_RS03240 45cf3716c7ef47f863f4d2df43083e49 247 Pfam PF12323 Helix-turn-helix domain 13 49 2.0E-10 T 28-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CP478_RS08230 9a83170827bd3780a9e6af0ac5e0c8ab 273 Gene3D G3DSA:2.60.120.620 4 225 2.0E-25 T 28-03-2018 CP478_RS08230 9a83170827bd3780a9e6af0ac5e0c8ab 273 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 21 209 1.0E-32 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CP478_RS08230 9a83170827bd3780a9e6af0ac5e0c8ab 273 SUPERFAMILY SSF51197 6 267 1.19E-41 T 28-03-2018 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 SUPERFAMILY SSF50621 268 404 4.88E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 SMART SM01005 274 403 1.4E-66 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 63 73 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 Pfam PF00842 Alanine racemase, C-terminal domain 274 402 4.0E-43 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 TIGRFAM TIGR00492 alr: alanine racemase 38 402 4.7E-96 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 Hamap MF_01201 Alanine racemase. 33 403 32.48 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 Gene3D G3DSA:3.20.20.10 34 246 8.7E-45 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 Pfam PF01168 Alanine racemase, N-terminal domain 40 262 9.9E-67 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 Gene3D G3DSA:2.40.37.10 247 408 3.1E-62 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 328 345 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 235 262 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 385 398 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 192 203 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 307 322 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 58 74 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 94 112 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 155 167 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 PRINTS PR00992 Alanine racemase signature 290 305 2.3E-71 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CP478_RS18730 d878599c3b486e09cb50478b2fca4662 408 SUPERFAMILY SSF51419 40 275 2.36E-59 T 28-03-2018 IPR029066 PLP-binding barrel CP478_RS11850 ecef8dd6c3f64a8be76f51c99b227d64 168 SUPERFAMILY SSF53098 4 156 9.26E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS11850 ecef8dd6c3f64a8be76f51c99b227d64 168 Hamap MF_00977 3'-5' exoribonuclease. 1 160 44.562 T 28-03-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 CP478_RS11850 ecef8dd6c3f64a8be76f51c99b227d64 168 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 5.0E-19 T 28-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain CP478_RS06900 561d28ff5ff9040e91b88dd54a841662 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 147 1.6E-40 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS06900 561d28ff5ff9040e91b88dd54a841662 149 Pfam PF04075 F420H(2)-dependent quinone reductase 16 147 6.1E-56 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS06900 561d28ff5ff9040e91b88dd54a841662 149 Gene3D G3DSA:2.30.110.10 11 149 1.8E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS18840 102667a09e8265587f25c87232e0f760 151 Pfam PF00380 Ribosomal protein S9/S16 31 151 5.4E-43 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CP478_RS18840 102667a09e8265587f25c87232e0f760 151 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 22 151 32.563 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CP478_RS18840 102667a09e8265587f25c87232e0f760 151 Gene3D G3DSA:3.30.230.10 24 151 3.6E-48 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CP478_RS18840 102667a09e8265587f25c87232e0f760 151 ProSitePatterns PS00360 Ribosomal protein S9 signature. 90 108 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CP478_RS18840 102667a09e8265587f25c87232e0f760 151 SUPERFAMILY SSF54211 27 151 2.05E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CP478_RS05975 3219646f451fd35fd0ee623a48f28f89 62 Pfam PF00553 Cellulose binding domain 6 58 2.1E-7 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CP478_RS05975 3219646f451fd35fd0ee623a48f28f89 62 Gene3D G3DSA:2.60.40.290 3 61 6.0E-8 T 28-03-2018 CP478_RS05975 3219646f451fd35fd0ee623a48f28f89 62 SUPERFAMILY SSF49384 9 57 1.95E-6 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CP478_RS01300 16baec802ad3b3d722154d3bcd154b37 145 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 142 4.0E-44 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS01300 16baec802ad3b3d722154d3bcd154b37 145 Gene3D G3DSA:3.40.50.1010 2 143 2.4E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01300 16baec802ad3b3d722154d3bcd154b37 145 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 14.376 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS01300 16baec802ad3b3d722154d3bcd154b37 145 SUPERFAMILY SSF88723 4 138 1.23E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01300 16baec802ad3b3d722154d3bcd154b37 145 Pfam PF01850 PIN domain 4 126 3.6E-9 T 28-03-2018 IPR002716 PIN domain CP478_RS07925 211413430a3531d620a0e1fd0004d996 247 SUPERFAMILY SSF100950 5 246 6.58E-67 T 28-03-2018 CP478_RS07925 211413430a3531d620a0e1fd0004d996 247 Gene3D G3DSA:3.40.50.1360 2 246 2.9E-78 T 28-03-2018 CP478_RS07925 211413430a3531d620a0e1fd0004d996 247 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 7 245 2.8E-80 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CP478_RS07925 211413430a3531d620a0e1fd0004d996 247 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 235 7.7E-75 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CP478_RS11260 d1814bcf063f6a2d4f6088ea193db4cc 208 SUPERFAMILY SSF63965 2 204 5.62E-68 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CP478_RS11260 d1814bcf063f6a2d4f6088ea193db4cc 208 Gene3D G3DSA:3.40.50.10230 2 208 5.6E-74 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CP478_RS11260 d1814bcf063f6a2d4f6088ea193db4cc 208 Pfam PF02570 Precorrin-8X methylmutase 10 204 1.8E-67 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CP478_RS00360 04b64e9d6e40d3d21c0bb0545ed86bc8 79 SUPERFAMILY SSF47598 2 66 2.56E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS00360 04b64e9d6e40d3d21c0bb0545ed86bc8 79 Gene3D G3DSA:1.10.1220.10 1 77 2.7E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS08710 7fced583fe04c109aafcb62c80ad149d 221 Pfam PF10821 Protein of unknown function (DUF2567) 32 198 6.0E-75 T 28-03-2018 IPR021213 Protein of unknown function DUF2567 CP478_RS06910 41c8d4784b3717f5358ec61306ed06c6 462 Gene3D G3DSA:3.90.1300.10 2 462 1.8E-118 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS06910 41c8d4784b3717f5358ec61306ed06c6 462 Pfam PF01425 Amidase 28 442 3.0E-98 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS06910 41c8d4784b3717f5358ec61306ed06c6 462 SUPERFAMILY SSF75304 4 459 1.57E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CP478_RS06910 41c8d4784b3717f5358ec61306ed06c6 462 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CP478_RS07755 06e635f09b7ed190ebd077bd0773ee12 154 Pfam PF10756 Bacterial PH domain 72 141 5.5E-24 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CP478_RS17920 3e4153d98b67952024cfde451efc50d5 229 Gene3D G3DSA:3.40.50.980 156 229 1.7E-7 T 28-03-2018 CP478_RS17920 3e4153d98b67952024cfde451efc50d5 229 SUPERFAMILY SSF56801 8 227 2.62E-18 T 28-03-2018 CP478_RS17920 3e4153d98b67952024cfde451efc50d5 229 Gene3D G3DSA:3.40.50.980 2 114 5.2E-7 T 28-03-2018 CP478_RS17920 3e4153d98b67952024cfde451efc50d5 229 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 1 226 2.5E-69 T 28-03-2018 IPR017523 Conserved hypothetical protein CHP03089 CP478_RS16520 5495d1c745ec667ebcf866b6269cb0a4 97 SUPERFAMILY SSF140453 4 93 6.41E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16520 5495d1c745ec667ebcf866b6269cb0a4 97 Pfam PF06013 Proteins of 100 residues with WXG 10 87 4.3E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16520 5495d1c745ec667ebcf866b6269cb0a4 97 Gene3D G3DSA:1.10.287.1060 1 97 2.8E-11 T 28-03-2018 CP478_RS15335 d936f57848a4d4cec20f50bb924f21d1 76 Gene3D G3DSA:1.10.1220.10 2 39 1.6E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS14110 776947866b5d85bbe480ef0506b5761e 167 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 20 155 3.4E-21 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS14110 776947866b5d85bbe480ef0506b5761e 167 SUPERFAMILY SSF55961 19 157 4.99E-24 T 28-03-2018 CP478_RS14110 776947866b5d85bbe480ef0506b5761e 167 Gene3D G3DSA:3.30.530.20 10 167 3.2E-22 T 28-03-2018 IPR023393 START-like domain CP478_RS20595 a31d634f552f4ead7c7e0a04229c9c4f 108 Gene3D G3DSA:1.10.357.10 6 102 2.8E-4 T 28-03-2018 CP478_RS01445 19cbc53863bef3521afc20d64137ca1a 169 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 90 143 8.9E-14 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS01445 19cbc53863bef3521afc20d64137ca1a 169 SUPERFAMILY SSF143120 90 141 1.96E-11 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS01445 19cbc53863bef3521afc20d64137ca1a 169 Gene3D G3DSA:3.40.1620.10 88 142 8.9E-15 T 28-03-2018 CP478_RS01445 19cbc53863bef3521afc20d64137ca1a 169 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 90 140 1.6E-13 T 28-03-2018 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 SUPERFAMILY SSF56645 37 294 1.22E-42 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Gene3D G3DSA:2.40.110.10 154 282 2.9E-24 T 28-03-2018 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 SUPERFAMILY SSF47203 292 469 2.9E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Gene3D G3DSA:1.10.540.10 31 151 9.2E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.1E-8 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Gene3D G3DSA:1.20.140.10 283 474 2.5E-30 T 28-03-2018 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 475 607 1.1E-29 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.5E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CP478_RS01320 151909868d526322a65445dba3b87ebb 611 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 1.5E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CP478_RS09260 d783d356eaba5c3e841e38096a0c94cc 393 SUPERFAMILY SSF63999 179 300 1.83E-13 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CP478_RS09260 d783d356eaba5c3e841e38096a0c94cc 393 Gene3D G3DSA:3.40.50.10240 176 274 2.2E-4 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CP478_RS09260 d783d356eaba5c3e841e38096a0c94cc 393 Pfam PF12555 Thiamine pyrophosphokinase C terminal 334 384 1.6E-17 T 28-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CP478_RS13790 ef242475cfbded2d78c6e2986d0497b8 408 SUPERFAMILY SSF141523 251 377 1.14E-28 T 28-03-2018 CP478_RS13790 ef242475cfbded2d78c6e2986d0497b8 408 Pfam PF03734 L,D-transpeptidase catalytic domain 260 377 6.1E-16 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CP478_RS13790 ef242475cfbded2d78c6e2986d0497b8 408 Gene3D G3DSA:2.40.440.10 252 378 8.2E-24 T 28-03-2018 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 SUPERFAMILY SSF117782 39 124 5.89E-16 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 Pfam PF01906 Putative heavy-metal-binding 64 122 2.4E-9 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 Pfam PF01906 Putative heavy-metal-binding 161 244 6.9E-9 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 SUPERFAMILY SSF117782 159 245 5.89E-16 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 Gene3D G3DSA:3.30.110.70 155 244 9.9E-19 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CP478_RS09600 db65fc1f05039a288f0ac9047addd714 262 Gene3D G3DSA:3.30.110.70 34 123 2.1E-18 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CP478_RS18100 51fcb0a11b996194a827f7a92bd4ab35 159 Pfam PF13772 AIG2-like family 59 145 2.5E-26 T 28-03-2018 CP478_RS18100 51fcb0a11b996194a827f7a92bd4ab35 159 Gene3D G3DSA:3.10.490.10 2 154 1.1E-35 T 28-03-2018 CP478_RS18100 51fcb0a11b996194a827f7a92bd4ab35 159 SUPERFAMILY SSF110857 3 125 1.7E-15 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CP478_RS11235 ddc30e29421a21c90ac2c94607222ded 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 88 2.3E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CP478_RS11235 ddc30e29421a21c90ac2c94607222ded 134 SUPERFAMILY SSF50475 8 119 9.17E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS11235 ddc30e29421a21c90ac2c94607222ded 134 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 132 5.1E-55 T 28-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CP478_RS11235 ddc30e29421a21c90ac2c94607222ded 134 Gene3D G3DSA:2.30.110.10 4 119 4.0E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS20660 695902c5a2bf50328bd0c1257f211875 273 SUPERFAMILY SSF52540 51 247 2.49E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20660 695902c5a2bf50328bd0c1257f211875 273 Gene3D G3DSA:3.40.50.300 7 272 1.1E-38 T 28-03-2018 CP478_RS20660 695902c5a2bf50328bd0c1257f211875 273 SMART SM00382 62 249 7.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS20660 695902c5a2bf50328bd0c1257f211875 273 Pfam PF00005 ABC transporter 53 183 1.3E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CP478_RS15415 d6577520acd8dcabddea3655303a94c8 382 Gene3D G3DSA:3.40.50.10770 3 116 4.7E-4 T 28-03-2018 CP478_RS15415 d6577520acd8dcabddea3655303a94c8 382 TIGRFAM TIGR02672 cas_csm6: CRISPR type III-A/MTUBE-associated protein Csm6 22 378 1.9E-159 T 28-03-2018 IPR013489 CRISPR-associated protein Csm6 CP478_RS15415 d6577520acd8dcabddea3655303a94c8 382 Pfam PF09659 CRISPR-associated protein (Cas_Csm6) 29 374 2.5E-116 T 28-03-2018 IPR013489 CRISPR-associated protein Csm6 CP478_RS13505 cdb5350039b7cdefe3411ebf7677988b 128 Pfam PF01152 Bacterial-like globin 4 121 3.1E-42 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CP478_RS13505 cdb5350039b7cdefe3411ebf7677988b 128 SUPERFAMILY SSF46458 4 127 5.35E-36 T 28-03-2018 IPR009050 Globin-like CP478_RS13505 cdb5350039b7cdefe3411ebf7677988b 128 Gene3D G3DSA:1.10.490.10 1 128 7.0E-34 T 28-03-2018 CP478_RS13505 cdb5350039b7cdefe3411ebf7677988b 128 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 51 75 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CP478_RS04805 5c25c489d3b50f0edb8c226169cbf2e1 288 Gene3D G3DSA:3.30.1330.30 17 118 4.9E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS04805 5c25c489d3b50f0edb8c226169cbf2e1 288 SUPERFAMILY SSF75217 109 280 1.05E-35 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CP478_RS04805 5c25c489d3b50f0edb8c226169cbf2e1 288 Gene3D G3DSA:3.40.1280.10 119 281 6.6E-39 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CP478_RS04805 5c25c489d3b50f0edb8c226169cbf2e1 288 Pfam PF00588 SpoU rRNA Methylase family 132 275 1.1E-29 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CP478_RS04805 5c25c489d3b50f0edb8c226169cbf2e1 288 SUPERFAMILY SSF55315 20 116 6.36E-10 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CP478_RS12705 e7e67eb77f3b936a0d2cbb66015591e8 175 ProDom PD091785 LIPOPROTEIN LPPP PALMITATE MEMBRANE PRECURSOR SIGNAL 23 175 4.0E-85 T 28-03-2018 IPR020217 Uncharacterised protein family, lipoprotein LppP CP478_RS12705 e7e67eb77f3b936a0d2cbb66015591e8 175 Pfam PF14041 LppP/LprE lipoprotein 79 162 2.0E-24 T 28-03-2018 IPR025971 LppP/LprE lipoprotein CP478_RS11230 7c92eee7d1caa7383061f4a21431f871 147 Pfam PF00950 ABC 3 transport family 1 141 1.1E-20 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CP478_RS11230 7c92eee7d1caa7383061f4a21431f871 147 SUPERFAMILY SSF81345 1 142 2.75E-18 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CP478_RS11230 7c92eee7d1caa7383061f4a21431f871 147 Gene3D G3DSA:1.10.3470.10 1 147 7.8E-14 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 SUPERFAMILY SSF56784 9 257 1.34E-49 T 28-03-2018 IPR023214 HAD-like domain CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 Gene3D G3DSA:3.40.50.1000 6 99 0.058 T 28-03-2018 IPR023214 HAD-like domain CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 108 1.2E-17 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 Gene3D G3DSA:3.40.50.1000 100 184 1.8E-24 T 28-03-2018 IPR023214 HAD-like domain CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 Pfam PF13242 HAD-hyrolase-like 184 256 1.1E-15 T 28-03-2018 CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 12 231 2.2E-31 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CP478_RS09235 258bc5387d1922a7d26bffc94548bfee 353 PIRSF PIRSF000915 1 262 3.3E-54 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 Pfam PF01255 Putative undecaprenyl diphosphate synthase 39 261 6.0E-66 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 262 33.138 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 SUPERFAMILY SSF64005 28 256 3.14E-70 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 Gene3D G3DSA:3.40.1180.10 18 262 2.0E-76 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05950 a92a46b5c11ba85b0262c6a38fa03fb7 262 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 261 5.3E-60 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS05675 4532ca32410366b7280de65664c5ee2f 94 SUPERFAMILY SSF140453 2 93 8.5E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS05675 4532ca32410366b7280de65664c5ee2f 94 Gene3D G3DSA:1.10.287.1060 1 94 4.2E-12 T 28-03-2018 CP478_RS05675 4532ca32410366b7280de65664c5ee2f 94 Pfam PF06013 Proteins of 100 residues with WXG 3 87 3.3E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS05675 4532ca32410366b7280de65664c5ee2f 94 PIRSF PIRSF037656 1 94 1.4E-56 T 28-03-2018 IPR009416 ESAT-6-like protein, Mycobacterium CP478_RS10125 a74a848d5f4b9302c3bfa570b86932a1 256 PIRSF PIRSF026622 11 256 3.8E-125 T 28-03-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type CP478_RS10125 a74a848d5f4b9302c3bfa570b86932a1 256 Pfam PF02517 CAAX protease self-immunity 132 242 9.3E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CP478_RS10240 bc1ff03b7a66e4dd874e1c6e13ee1365 153 SUPERFAMILY SSF55961 6 152 3.67E-20 T 28-03-2018 CP478_RS10240 bc1ff03b7a66e4dd874e1c6e13ee1365 153 Gene3D G3DSA:3.30.530.20 7 153 6.1E-24 T 28-03-2018 IPR023393 START-like domain CP478_RS10240 bc1ff03b7a66e4dd874e1c6e13ee1365 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 151 6.4E-17 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS10830 e81632afbee444a134ce0e0c2fd7a05a 90 Gene3D G3DSA:3.40.50.1010 3 74 6.7E-6 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10830 e81632afbee444a134ce0e0c2fd7a05a 90 SUPERFAMILY SSF88723 9 63 5.05E-6 T 28-03-2018 IPR029060 PIN domain-like CP478_RS00220 9985ee09c8cbb7805d7aa70df43fbeb0 115 ProDom PD029828 TRANSMEMBRANE MEMBRANE ML0030 POSSIBLE RV0039C/MT0044 1 114 2.0E-45 T 28-03-2018 CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 Gene3D G3DSA:1.20.120.570 134 284 6.4E-5 T 28-03-2018 CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 Pfam PF02470 MlaD protein 39 112 1.1E-10 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 292 1.3E-84 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 346 364 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 325 342 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS03165 1bbe6edfa147e53f1a13bec5ac5a32b3 481 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 1.5E-97 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS05050 3ccd5aac728031993743b1de3f6f35a5 245 Gene3D G3DSA:3.40.50.360 14 220 2.9E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS05050 3ccd5aac728031993743b1de3f6f35a5 245 Pfam PF03358 NADPH-dependent FMN reductase 19 171 3.8E-11 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CP478_RS05050 3ccd5aac728031993743b1de3f6f35a5 245 SUPERFAMILY SSF52218 19 244 6.86E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS13655 73ec15c5e7fa94d5f1523a42ac0190a5 367 SUPERFAMILY SSF52518 38 361 7.33E-103 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS13655 73ec15c5e7fa94d5f1523a42ac0190a5 367 Pfam PF00676 Dehydrogenase E1 component 48 333 2.6E-84 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CP478_RS13655 73ec15c5e7fa94d5f1523a42ac0190a5 367 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 19 358 1.6E-135 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CP478_RS13655 73ec15c5e7fa94d5f1523a42ac0190a5 367 Gene3D G3DSA:3.40.50.970 28 335 3.1E-92 T 28-03-2018 CP478_RS02575 2601fc6e63461c934f5a925e70a3c80c 451 Gene3D G3DSA:2.40.440.10 258 385 6.1E-19 T 28-03-2018 CP478_RS02575 2601fc6e63461c934f5a925e70a3c80c 451 Pfam PF03734 L,D-transpeptidase catalytic domain 265 383 1.0E-11 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CP478_RS02575 2601fc6e63461c934f5a925e70a3c80c 451 SUPERFAMILY SSF141523 262 383 2.75E-19 T 28-03-2018 CP478_RS12120 4d94ef60a3fd7760d69543401a04512c 245 Gene3D G3DSA:1.20.120.330 16 178 3.1E-10 T 28-03-2018 CP478_RS12120 4d94ef60a3fd7760d69543401a04512c 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 1.2E-10 T 28-03-2018 IPR003743 C4-type zinc ribbon domain CP478_RS12250 f7213f2e73ec7cb57af939916ba6e1a6 309 SUPERFAMILY SSF111331 13 307 9.37E-68 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CP478_RS12250 f7213f2e73ec7cb57af939916ba6e1a6 309 Gene3D G3DSA:3.40.50.10330 8 145 2.0E-28 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CP478_RS12250 f7213f2e73ec7cb57af939916ba6e1a6 309 SMART SM00046 13 145 8.9E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CP478_RS12250 f7213f2e73ec7cb57af939916ba6e1a6 309 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 14 306 3.6E-40 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CP478_RS12250 f7213f2e73ec7cb57af939916ba6e1a6 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 14 136 9.6E-28 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 SUPERFAMILY SSF140459 8 84 6.28E-25 T 28-03-2018 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 PRINTS PR01228 Eggshell protein signature 273 291 5.7E-7 T 28-03-2018 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 PRINTS PR01228 Eggshell protein signature 135 146 5.7E-7 T 28-03-2018 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 PRINTS PR01228 Eggshell protein signature 220 235 5.7E-7 T 28-03-2018 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 PRINTS PR01228 Eggshell protein signature 247 257 5.7E-7 T 28-03-2018 CP478_RS15025 8e3bbce38171fdd2ae99b377a7311fda 525 Pfam PF00934 PE family 1 93 6.5E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS18600 7d7b72828a8fdd5b8db232196d2caac3 359 SUPERFAMILY SSF48576 36 358 4.64E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS18600 7d7b72828a8fdd5b8db232196d2caac3 359 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 109 123 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS18600 7d7b72828a8fdd5b8db232196d2caac3 359 Pfam PF00348 Polyprenyl synthetase 69 286 2.8E-53 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CP478_RS18600 7d7b72828a8fdd5b8db232196d2caac3 359 Gene3D G3DSA:1.10.600.10 13 359 3.3E-90 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS18600 7d7b72828a8fdd5b8db232196d2caac3 359 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 234 246 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS14235 a38a519599fd5eb16eb56273d833d432 164 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 3 159 7.0E-85 T 28-03-2018 IPR024486 Protein of unknown function DUF2617 CP478_RS14235 a38a519599fd5eb16eb56273d833d432 164 Pfam PF10936 Protein of unknown function DUF2617 4 162 1.2E-53 T 28-03-2018 IPR024486 Protein of unknown function DUF2617 CP478_RS02920 e746f6e5fb46b3fbb4c3e0b519f0e274 417 Pfam PF01384 Phosphate transporter family 22 321 5.1E-76 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CP478_RS20175 984553f5da5c5148d9c13928dee5705a 440 Pfam PF01882 Protein of unknown function DUF58 187 280 1.8E-18 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CP478_RS20175 984553f5da5c5148d9c13928dee5705a 440 Gene3D G3DSA:3.40.50.410 199 416 3.0E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS14690 c99430d7982e4be9efec6e0c2227cb71 276 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CP478_RS14690 c99430d7982e4be9efec6e0c2227cb71 276 SUPERFAMILY SSF52096 21 266 8.71E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS14690 c99430d7982e4be9efec6e0c2227cb71 276 Gene3D G3DSA:3.90.226.10 15 225 1.6E-46 T 28-03-2018 CP478_RS14690 c99430d7982e4be9efec6e0c2227cb71 276 Gene3D G3DSA:1.10.12.10 226 271 2.2E-10 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS14690 c99430d7982e4be9efec6e0c2227cb71 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 267 8.3E-40 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS10390 d5fb447674e6acb5a5db14d003e80a33 150 SUPERFAMILY SSF46785 9 139 2.09E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS10390 d5fb447674e6acb5a5db14d003e80a33 150 Pfam PF01475 Ferric uptake regulator family 17 124 2.5E-18 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CP478_RS10390 d5fb447674e6acb5a5db14d003e80a33 150 Gene3D G3DSA:1.10.10.10 3 88 4.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02765 b8678039a6e6dc3c707ae3cc08bdfe7d 436 Pfam PF01757 Acyltransferase family 38 387 5.0E-22 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CP478_RS09710 feed843bc7c022b1ca9a383d48c33ba2 506 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 16 494 1.4E-154 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS09710 feed843bc7c022b1ca9a383d48c33ba2 506 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 18 482 1.6E-157 T 28-03-2018 IPR007795 Type VII secretion system EccB CP478_RS13050 d666dff2c83c1e93eb94f6e575657663 281 Gene3D G3DSA:3.40.50.1400 38 150 4.0E-23 T 28-03-2018 CP478_RS13050 d666dff2c83c1e93eb94f6e575657663 281 Gene3D G3DSA:3.40.50.1400 151 262 2.9E-20 T 28-03-2018 CP478_RS13050 d666dff2c83c1e93eb94f6e575657663 281 Pfam PF01903 CbiX 173 266 3.2E-11 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CP478_RS13050 d666dff2c83c1e93eb94f6e575657663 281 Pfam PF01903 CbiX 53 150 1.3E-16 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CP478_RS13050 d666dff2c83c1e93eb94f6e575657663 281 SUPERFAMILY SSF53800 48 275 1.12E-32 T 28-03-2018 CP478_RS20030 3f6f939f445414bef91de569c3a2ea1a 232 SUPERFAMILY SSF50494 40 203 3.64E-23 T 28-03-2018 IPR009003 Peptidase S1, PA clan CP478_RS20030 3f6f939f445414bef91de569c3a2ea1a 232 Gene3D G3DSA:2.40.10.10 35 121 1.2E-15 T 28-03-2018 CP478_RS09275 d9ef16d45827ea8268738c454b364ed3 207 Pfam PF00293 NUDIX domain 45 156 1.5E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CP478_RS09275 d9ef16d45827ea8268738c454b364ed3 207 Gene3D G3DSA:3.90.79.10 1 184 2.1E-35 T 28-03-2018 CP478_RS09275 d9ef16d45827ea8268738c454b364ed3 207 SUPERFAMILY SSF55811 5 177 1.62E-44 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CP478_RS19410 fec00d18bfcc419c63ffc904dc6172ae 292 SMART SM00882 5 233 3.6E-24 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS19410 fec00d18bfcc419c63ffc904dc6172ae 292 Pfam PF01144 Coenzyme A transferase 7 233 4.6E-49 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CP478_RS19410 fec00d18bfcc419c63ffc904dc6172ae 292 Gene3D G3DSA:3.40.1080.10 2 255 1.5E-52 T 28-03-2018 CP478_RS19410 fec00d18bfcc419c63ffc904dc6172ae 292 SUPERFAMILY SSF100950 3 280 1.26E-62 T 28-03-2018 CP478_RS16765 15a37d3ef9366aa70340d6bf3c779d0e 141 Pfam PF07681 DoxX 17 93 6.4E-10 T 28-03-2018 IPR032808 DoxX family CP478_RS21270 ff2f7ce36a57468be5cc7e5bc419b4e5 399 Pfam PF00823 PPE family 9 166 1.4E-23 T 28-03-2018 IPR000030 PPE family CP478_RS21270 ff2f7ce36a57468be5cc7e5bc419b4e5 399 SUPERFAMILY SSF140459 6 175 3.92E-30 T 28-03-2018 CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 SUPERFAMILY SSF160240 240 319 1.7E-16 T 28-03-2018 CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 Gene3D G3DSA:3.30.70.1350 236 320 6.9E-19 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 Gene3D G3DSA:1.20.1510.10 41 235 3.6E-38 T 28-03-2018 CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 Pfam PF16916 Dimerisation domain of Zinc Transporter 241 317 4.3E-15 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 SUPERFAMILY SSF161111 41 238 1.18E-47 T 28-03-2018 CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 Pfam PF01545 Cation efflux family 45 237 8.7E-43 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CP478_RS11055 25a6b58aacdfcc541a2f8e8ed8da68c3 332 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 42 319 7.7E-75 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CP478_RS06285 e9781c7bfb75b344e161fff1982e2ae3 216 Pfam PF13489 Methyltransferase domain 26 188 8.1E-16 T 28-03-2018 CP478_RS06285 e9781c7bfb75b344e161fff1982e2ae3 216 SUPERFAMILY SSF53335 39 210 3.31E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS06285 e9781c7bfb75b344e161fff1982e2ae3 216 Gene3D G3DSA:3.40.50.150 5 199 2.2E-20 T 28-03-2018 CP478_RS12870 2cec97575248cdc2617b825f9db1f03b 130 Pfam PF01475 Ferric uptake regulator family 4 121 3.2E-39 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CP478_RS12870 2cec97575248cdc2617b825f9db1f03b 130 SUPERFAMILY SSF46785 3 127 3.64E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS12870 2cec97575248cdc2617b825f9db1f03b 130 Gene3D G3DSA:1.10.10.10 1 82 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS13245 f56e41a888af9d19f5ba20253835a384 291 SUPERFAMILY SSF52540 40 280 1.84E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS13245 f56e41a888af9d19f5ba20253835a384 291 Gene3D G3DSA:3.40.50.300 26 235 5.9E-30 T 28-03-2018 CP478_RS13245 f56e41a888af9d19f5ba20253835a384 291 Pfam PF07728 AAA domain (dynein-related subfamily) 46 194 7.2E-11 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CP478_RS13245 f56e41a888af9d19f5ba20253835a384 291 SMART SM00382 42 205 6.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19890 f371c6537bf74177e704dec777164c40 401 Gene3D G3DSA:3.40.50.300 24 181 7.1E-26 T 28-03-2018 CP478_RS19890 f371c6537bf74177e704dec777164c40 401 Pfam PF13177 DNA polymerase III, delta subunit 37 179 4.1E-35 T 28-03-2018 CP478_RS19890 f371c6537bf74177e704dec777164c40 401 Gene3D G3DSA:1.20.272.10 293 401 7.9E-25 T 28-03-2018 CP478_RS19890 f371c6537bf74177e704dec777164c40 401 SMART SM00382 39 182 3.8E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS19890 f371c6537bf74177e704dec777164c40 401 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 36 216 2.5E-58 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CP478_RS19890 f371c6537bf74177e704dec777164c40 401 SUPERFAMILY SSF52540 6 220 6.4E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19890 f371c6537bf74177e704dec777164c40 401 SUPERFAMILY SSF48019 318 390 3.06E-5 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CP478_RS13940 dec0bf6e991ca98456b7f066b1b8d85e 219 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 41 194 2.9E-43 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CP478_RS06985 cc7d0be121d50de97f991a9a5a2be82f 417 PIRSF PIRSF033093 34 417 6.0E-176 T 28-03-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type CP478_RS06985 cc7d0be121d50de97f991a9a5a2be82f 417 Gene3D G3DSA:3.60.21.10 107 290 5.4E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS06985 cc7d0be121d50de97f991a9a5a2be82f 417 Gene3D G3DSA:3.60.21.10 27 106 1.4E-9 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS06985 cc7d0be121d50de97f991a9a5a2be82f 417 SUPERFAMILY SSF56300 35 345 8.2E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CP478_RS06985 cc7d0be121d50de97f991a9a5a2be82f 417 Pfam PF00149 Calcineurin-like phosphoesterase 35 203 1.2E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Gene3D G3DSA:3.40.50.300 307 410 3.5E-27 T 28-03-2018 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Gene3D G3DSA:3.40.50.300 446 698 5.1E-50 T 28-03-2018 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Gene3D G3DSA:3.40.50.300 158 306 7.8E-34 T 28-03-2018 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Gene3D G3DSA:3.40.50.300 16 157 1.9E-26 T 28-03-2018 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Pfam PF00580 UvrD/REP helicase N-terminal domain 23 296 3.2E-75 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 19 768 1.7E-278 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 Pfam PF13361 UvrD-like helicase C-terminal domain 302 652 7.4E-68 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CP478_RS05180 f3e8a77981bbea4700da65ceb94d3655 771 SUPERFAMILY SSF52540 16 681 4.41E-174 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS14695 75d517ae4af3d3c8eea078196ef4befc 210 Pfam PF11452 Protein of unknown function (DUF3000) 23 202 2.9E-73 T 28-03-2018 IPR021555 Protein of unknown function DUF3000 CP478_RS17580 5153f5d4203f125c0f80c0c63ebf6842 285 Gene3D G3DSA:3.40.390.10 101 271 1.4E-8 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CP478_RS17580 5153f5d4203f125c0f80c0c63ebf6842 285 Pfam PF11350 Protein of unknown function (DUF3152) 73 283 3.7E-105 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 CP478_RS17580 5153f5d4203f125c0f80c0c63ebf6842 285 SUPERFAMILY SSF55486 68 253 3.34E-21 T 28-03-2018 CP478_RS17580 5153f5d4203f125c0f80c0c63ebf6842 285 SMART SM00235 83 269 9.4E-17 T 28-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 CP478_RS03005 65b9a0323b02bf006cca309ee3dd1a1b 335 Gene3D G3DSA:1.10.600.10 8 335 1.1E-98 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS03005 65b9a0323b02bf006cca309ee3dd1a1b 335 SUPERFAMILY SSF48576 22 334 6.91E-81 T 28-03-2018 IPR008949 Isoprenoid synthase domain CP478_RS03005 65b9a0323b02bf006cca309ee3dd1a1b 335 Pfam PF00348 Polyprenyl synthetase 43 285 5.4E-63 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CP478_RS03005 65b9a0323b02bf006cca309ee3dd1a1b 335 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CP478_RS06570 906ec5b8a0adf2337f90ab835052ecf6 415 Pfam PF00872 Transposase, Mutator family 1 379 3.5E-154 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS06570 906ec5b8a0adf2337f90ab835052ecf6 415 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS13740 906ec5b8a0adf2337f90ab835052ecf6 415 Pfam PF00872 Transposase, Mutator family 1 379 3.5E-154 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS13740 906ec5b8a0adf2337f90ab835052ecf6 415 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CP478_RS18315 a08736099b998f226ab6e308a86d435a 85 Pfam PF11222 Protein of unknown function (DUF3017) 17 78 9.5E-19 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 CP478_RS19810 9ad8b7808b1a715426d7cd7a1fe2ba39 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CP478_RS19810 9ad8b7808b1a715426d7cd7a1fe2ba39 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 35.627 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CP478_RS19810 9ad8b7808b1a715426d7cd7a1fe2ba39 162 SUPERFAMILY SSF50324 3 159 2.62E-60 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CP478_RS19810 9ad8b7808b1a715426d7cd7a1fe2ba39 162 Pfam PF00719 Inorganic pyrophosphatase 5 158 8.8E-55 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CP478_RS19810 9ad8b7808b1a715426d7cd7a1fe2ba39 162 Gene3D G3DSA:3.90.80.10 1 162 1.9E-52 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CP478_RS17270 a9a02a7d64c4bdb8b0d60c8ca2b76e1f 262 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 31 176 1.2E-28 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS06945 971c6f8959d53af28f22fe141891e2ad 124 Pfam PF13827 Domain of unknown function (DUF4189) 39 115 1.9E-18 T 28-03-2018 IPR025240 Domain of unknown function DUF4189 CP478_RS06945 971c6f8959d53af28f22fe141891e2ad 124 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 37 124 3.0E-50 T 28-03-2018 CP478_RS06865 238a8918aa98e9bc331d32965013508a 383 Pfam PF01757 Acyltransferase family 23 372 7.2E-28 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CP478_RS06345 d4a16839e5094616e11aa1aebeb8a0ed 195 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 25 191 1.3E-25 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CP478_RS06345 d4a16839e5094616e11aa1aebeb8a0ed 195 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 3 190 7.4E-105 T 28-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD CP478_RS06345 d4a16839e5094616e11aa1aebeb8a0ed 195 Gene3D G3DSA:1.10.340.30 16 140 3.8E-13 T 28-03-2018 CP478_RS06345 d4a16839e5094616e11aa1aebeb8a0ed 195 SUPERFAMILY SSF48150 14 142 5.5E-15 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CP478_RS17630 a065b748c88faf7d5152f5524b7050a0 110 Gene3D G3DSA:3.40.630.30 37 109 2.8E-8 T 28-03-2018 CP478_RS17630 a065b748c88faf7d5152f5524b7050a0 110 SUPERFAMILY SSF55729 3 101 7.26E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS17630 a065b748c88faf7d5152f5524b7050a0 110 Pfam PF00583 Acetyltransferase (GNAT) family 5 86 1.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS17630 a065b748c88faf7d5152f5524b7050a0 110 Gene3D G3DSA:3.40.630.30 1 36 8.0E-10 T 28-03-2018 CP478_RS20365 37091371ca9d5f9a650a1d47493eeb84 602 Pfam PF01593 Flavin containing amine oxidoreductase 17 324 2.5E-16 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CP478_RS20365 37091371ca9d5f9a650a1d47493eeb84 602 Gene3D G3DSA:3.50.50.60 2 548 2.2E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20365 37091371ca9d5f9a650a1d47493eeb84 602 SUPERFAMILY SSF51905 250 331 1.02E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20365 37091371ca9d5f9a650a1d47493eeb84 602 SUPERFAMILY SSF51905 9 181 1.02E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS20365 37091371ca9d5f9a650a1d47493eeb84 602 SUPERFAMILY SSF51905 488 563 1.02E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS15185 69e0f63df799048507995907577b3cd1 157 Gene3D G3DSA:1.25.40.10 30 154 1.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 Gene3D G3DSA:3.40.50.980 191 389 6.0E-37 T 28-03-2018 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 Pfam PF00501 AMP-binding enzyme 27 467 1.5E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 Gene3D G3DSA:3.40.50.980 13 190 1.1E-33 T 28-03-2018 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 Gene3D G3DSA:3.30.300.30 462 599 1.4E-17 T 28-03-2018 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 Gene3D G3DSA:2.30.38.10 390 460 1.0E-21 T 28-03-2018 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 SUPERFAMILY SSF56801 338 598 3.27E-113 T 28-03-2018 CP478_RS11890 04ca9cdde17d0a660e536845af769db9 600 SUPERFAMILY SSF56801 17 290 3.27E-113 T 28-03-2018 CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 PRINTS PR01576 Peptide deformylase signature 104 115 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 PRINTS PR01576 Peptide deformylase signature 38 67 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 PRINTS PR01576 Peptide deformylase signature 135 164 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 PRINTS PR01576 Peptide deformylase signature 116 134 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 SUPERFAMILY SSF56420 3 188 1.44E-47 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 Hamap MF_00163 Peptide deformylase [def]. 2 177 25.64 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 PIRSF PIRSF004749 1 182 4.1E-36 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 Pfam PF01327 Polypeptide deformylase 5 162 1.1E-37 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 Gene3D G3DSA:3.90.45.10 1 178 8.2E-52 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS02285 e2b27d628d749a58343f042d403cb9e6 197 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 28 167 2.5E-31 T 28-03-2018 IPR023635 Peptide deformylase CP478_RS00270 a88148c183b76a899df71865c9407685 137 Pfam PF17249 Family of unknown function (DUF5318) 1 117 8.1E-59 T 28-03-2018 IPR035169 Protein of unknown function DUF5318 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 Gene3D G3DSA:3.40.1130.10 254 482 6.0E-14 T 28-03-2018 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 SUPERFAMILY SSF69593 268 452 1.03E-9 T 28-03-2018 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 SMART SM00563 270 397 2.2E-10 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 Pfam PF01553 Acyltransferase 266 379 5.1E-14 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 1 778 24.985 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 PIRSF PIRSF500064 1 789 2.8E-219 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 CP478_RS13570 6ac016db7d16f2b5c7311085f985e153 789 PIRSF PIRSF000437 1 787 5.9E-208 T 28-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 CP478_RS03325 e374d84c6c307c4652b83409f0208945 163 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 15 125 4.0E-13 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CP478_RS03325 e374d84c6c307c4652b83409f0208945 163 Gene3D G3DSA:3.30.428.10 1 162 3.7E-25 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS03325 e374d84c6c307c4652b83409f0208945 163 SUPERFAMILY SSF54197 5 161 5.95E-35 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CP478_RS08275 28e334bcea134b1a2e6c9c93484c1ddd 293 Gene3D G3DSA:3.40.50.150 19 202 6.3E-14 T 28-03-2018 CP478_RS08275 28e334bcea134b1a2e6c9c93484c1ddd 293 Pfam PF13489 Methyltransferase domain 44 167 7.3E-8 T 28-03-2018 CP478_RS08275 28e334bcea134b1a2e6c9c93484c1ddd 293 SUPERFAMILY SSF53335 48 223 4.14E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS01705 f87b54a71b05368d6c0d3840aa743492 264 Pfam PF02535 ZIP Zinc transporter 131 263 1.7E-9 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CP478_RS03670 204e38814c01aa1b86b7b9bdd3931a9c 165 Pfam PF11259 Protein of unknown function (DUF3060) 101 159 2.2E-21 T 28-03-2018 IPR021417 Protein of unknown function DUF3060 CP478_RS16505 615893a82c63e793da6cccd9073ee361 434 Pfam PF00823 PPE family 8 164 7.5E-58 T 28-03-2018 IPR000030 PPE family CP478_RS16505 615893a82c63e793da6cccd9073ee361 434 SUPERFAMILY SSF140459 5 177 4.71E-60 T 28-03-2018 CP478_RS16505 615893a82c63e793da6cccd9073ee361 434 Gene3D G3DSA:1.10.287.1060 23 106 2.3E-5 T 28-03-2018 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 Gene3D G3DSA:1.25.40.10 7 253 4.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 Gene3D G3DSA:3.40.50.300 271 464 2.1E-25 T 28-03-2018 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 SMART SM00382 326 467 1.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 330 464 7.1E-22 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 TIGRFAM TIGR03922 T7SS_EccA: type VII secretion AAA-ATPase EccA 27 566 4.0E-216 T 28-03-2018 IPR023835 Type VII secretion system AAA-ATPase, EccA CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 435 452 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 452 471 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 517 529 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 329 344 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 367 381 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 289 303 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 381 400 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 PRINTS PR00819 CbxX/CfqX superfamily signature 414 426 2.2E-53 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CP478_RS21145 81e9a1ecbe07c68c439e6ea4445fc013 573 SUPERFAMILY SSF52540 290 547 3.24E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS18255 5d7b4a8fc03d4cd5505071a429a15365 281 Pfam PF05305 Protein of unknown function (DUF732) 16 120 2.1E-23 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 39.161 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 4.7E-58 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 SUPERFAMILY SSF51351 2 253 2.88E-88 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 Gene3D G3DSA:3.20.20.70 1 257 8.8E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS07865 0af35807ac720353a2e88075643c0a19 261 Pfam PF00121 Triosephosphate isomerase 6 251 1.8E-87 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CP478_RS19130 4f76c36b85379e234e5bd04c55e9f9a4 350 Pfam PF02470 MlaD protein 43 118 1.2E-16 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS19130 4f76c36b85379e234e5bd04c55e9f9a4 350 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 298 2.9E-84 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19130 4f76c36b85379e234e5bd04c55e9f9a4 350 Gene3D G3DSA:3.90.20.10 146 302 1.4E-4 T 28-03-2018 CP478_RS03315 b2df2bffda58b743a9ba4a475d944a10 133 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 2 131 4.7E-36 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS03315 b2df2bffda58b743a9ba4a475d944a10 133 Gene3D G3DSA:3.40.50.1010 1 129 1.6E-13 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03315 b2df2bffda58b743a9ba4a475d944a10 133 Pfam PF01850 PIN domain 3 120 6.0E-10 T 28-03-2018 IPR002716 PIN domain CP478_RS03315 b2df2bffda58b743a9ba4a475d944a10 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 14.758 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03315 b2df2bffda58b743a9ba4a475d944a10 133 SUPERFAMILY SSF88723 3 129 3.64E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 Gene3D G3DSA:3.40.50.300 1 445 3.4E-14 T 28-03-2018 CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 Gene3D G3DSA:3.40.50.300 457 861 3.5E-8 T 28-03-2018 CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 Pfam PF13175 AAA ATPase domain 2 61 1.2E-8 T 28-03-2018 CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 SUPERFAMILY SSF52540 223 259 3.04E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 SUPERFAMILY SSF52540 744 857 3.04E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 SUPERFAMILY SSF52540 2 130 3.04E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS06990 c63f4b4cfbc8a5604ceebc3fdc9ce925 875 SUPERFAMILY SSF52540 661 675 3.04E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20185 cdc347b2bf39ce3b4d6d48deaabbae23 310 Pfam PF06271 RDD family 18 137 4.9E-14 T 28-03-2018 IPR010432 RDD CP478_RS14875 52d4cd41e9e8e115752c4395c3da21c4 324 PIRSF PIRSF028754 21 324 3.0E-133 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CP478_RS14875 52d4cd41e9e8e115752c4395c3da21c4 324 Pfam PF09754 PAC2 family 44 260 1.9E-42 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CP478_RS14875 52d4cd41e9e8e115752c4395c3da21c4 324 SUPERFAMILY SSF159659 20 285 1.03E-85 T 28-03-2018 CP478_RS14875 52d4cd41e9e8e115752c4395c3da21c4 324 Gene3D G3DSA:1.10.287.100 242 282 5.7E-16 T 28-03-2018 CP478_RS00125 60af3b46b389e042e1c023aa958260fa 322 Gene3D G3DSA:3.20.20.70 1 322 4.4E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS00125 60af3b46b389e042e1c023aa958260fa 322 Pfam PF03060 Nitronate monooxygenase 81 308 4.3E-30 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS00125 60af3b46b389e042e1c023aa958260fa 322 Pfam PF03060 Nitronate monooxygenase 6 56 2.1E-9 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CP478_RS00125 60af3b46b389e042e1c023aa958260fa 322 SUPERFAMILY SSF51412 3 316 1.24E-52 T 28-03-2018 CP478_RS10955 59bc1d9c9c76b76669850433c918582e 132 Pfam PF01850 PIN domain 1 120 1.1E-14 T 28-03-2018 IPR002716 PIN domain CP478_RS10955 59bc1d9c9c76b76669850433c918582e 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 127 15.441 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS10955 59bc1d9c9c76b76669850433c918582e 132 SUPERFAMILY SSF88723 2 120 1.63E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10955 59bc1d9c9c76b76669850433c918582e 132 Gene3D G3DSA:3.40.50.1010 1 132 5.2E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10985 b7c45f7a7ebafb4994173c738b767e91 215 Pfam PF01548 Transposase 1 151 4.5E-33 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CP478_RS01055 3aa79247f6a9f81860eb7cce4ec5c3e1 615 SUPERFAMILY SSF51197 103 331 2.33E-7 T 28-03-2018 CP478_RS01055 3aa79247f6a9f81860eb7cce4ec5c3e1 615 Gene3D G3DSA:2.60.120.620 87 342 1.3E-4 T 28-03-2018 CP478_RS08310 5cdb4135625395789c6c4961ae1331e5 298 Gene3D G3DSA:3.40.50.150 60 288 3.3E-17 T 28-03-2018 CP478_RS08310 5cdb4135625395789c6c4961ae1331e5 298 SUPERFAMILY SSF53335 67 186 1.45E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS08310 5cdb4135625395789c6c4961ae1331e5 298 Pfam PF13847 Methyltransferase domain 68 163 3.2E-7 T 28-03-2018 IPR025714 Methyltransferase domain CP478_RS14755 c76160e101be0c94cb44e4a3de1b70e9 657 Pfam PF13520 Amino acid permease 59 458 2.1E-21 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS15320 7d5e136b42e03d11d9e1ae75613a5a95 209 Pfam PF12079 Protein of unknown function (DUF3558) 51 176 3.1E-8 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CP478_RS15115 ed769ff49f48845ea60725d2558a6dc3 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 131 13.872 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS15115 ed769ff49f48845ea60725d2558a6dc3 131 Gene3D G3DSA:3.40.50.1010 1 127 5.2E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15115 ed769ff49f48845ea60725d2558a6dc3 131 Pfam PF01850 PIN domain 1 125 1.6E-15 T 28-03-2018 IPR002716 PIN domain CP478_RS15115 ed769ff49f48845ea60725d2558a6dc3 131 SUPERFAMILY SSF88723 1 127 5.23E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 SUPERFAMILY SSF46785 20 112 4.44E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 59 77 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 Pfam PF01022 Bacterial regulatory protein, arsR family 40 89 3.2E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 68 1.5E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 85 100 1.5E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.5E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 1.5E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 SMART SM00418 33 113 2.7E-31 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS14470 6f1ade87cb11ccd164ba88846d628650 126 Gene3D G3DSA:1.10.10.10 11 121 8.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 149 164 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 342 353 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 86 97 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 284 311 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 189 211 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 333 342 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00359 B-class P450 signature 267 278 4.7E-32 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 Gene3D G3DSA:1.10.630.10 30 392 1.5E-56 T 28-03-2018 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 Pfam PF00067 Cytochrome P450 328 390 7.7E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 Pfam PF00067 Cytochrome P450 199 313 1.8E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 SUPERFAMILY SSF48264 29 392 1.44E-74 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00385 P450 superfamily signature 232 249 4.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00385 P450 superfamily signature 333 342 4.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00385 P450 superfamily signature 342 353 4.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS09720 1bfd720fb03e3d6391369318426b4de5 393 PRINTS PR00385 P450 superfamily signature 267 278 4.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS03645 f026446b99e967ade3f03e0d289f500c 240 Gene3D G3DSA:1.10.10.10 1 75 6.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03645 f026446b99e967ade3f03e0d289f500c 240 Pfam PF07848 PaaX-like protein 6 66 1.6E-16 T 28-03-2018 IPR012906 PaaX-like, N-terminal CP478_RS03645 f026446b99e967ade3f03e0d289f500c 240 Pfam PF08223 PaaX-like protein C-terminal domain 186 229 4.7E-7 T 28-03-2018 IPR013225 PaaX-like, C-terminal CP478_RS21210 15b0ff10c86f2c26c01dd912a6c04efa 115 Pfam PF02575 YbaB/EbfC DNA-binding family 17 102 9.5E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS21210 15b0ff10c86f2c26c01dd912a6c04efa 115 Gene3D G3DSA:3.30.1310.10 7 112 4.2E-16 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS21210 15b0ff10c86f2c26c01dd912a6c04efa 115 SUPERFAMILY SSF82607 20 101 7.85E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS09680 d9144d99be9e72c70542b52069e2132d 186 SUPERFAMILY SSF46689 12 80 3.79E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS09680 d9144d99be9e72c70542b52069e2132d 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS09680 d9144d99be9e72c70542b52069e2132d 186 Gene3D G3DSA:1.10.357.10 12 185 4.7E-18 T 28-03-2018 CP478_RS05945 9cd464c893c50caa2e4a1f26ce5e505b 242 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 34 241 2.3E-65 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CP478_RS05945 9cd464c893c50caa2e4a1f26ce5e505b 242 Pfam PF03006 Haemolysin-III related 32 234 4.3E-42 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CP478_RS00785 4b2e6a269418b0d1cad3ad32d49bbd2c 317 SUPERFAMILY SSF53335 27 307 9.58E-81 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS00785 4b2e6a269418b0d1cad3ad32d49bbd2c 317 Gene3D G3DSA:3.40.50.150 10 302 2.4E-58 T 28-03-2018 CP478_RS00785 4b2e6a269418b0d1cad3ad32d49bbd2c 317 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 29 290 8.9E-85 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS00785 4b2e6a269418b0d1cad3ad32d49bbd2c 317 Pfam PF04072 Leucine carboxyl methyltransferase 31 213 1.5E-61 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS05015 2ce9ac4addbf8f72d18ac2f421157629 166 Pfam PF00583 Acetyltransferase (GNAT) family 38 143 3.6E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS05015 2ce9ac4addbf8f72d18ac2f421157629 166 SUPERFAMILY SSF55729 19 150 2.3E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS05015 2ce9ac4addbf8f72d18ac2f421157629 166 Gene3D G3DSA:3.40.630.30 7 150 1.1E-17 T 28-03-2018 CP478_RS07655 84515db4884b109b896ca11f0504e9cc 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 124 14.669 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS07655 84515db4884b109b896ca11f0504e9cc 133 SUPERFAMILY SSF88723 1 121 5.33E-22 T 28-03-2018 IPR029060 PIN domain-like CP478_RS07655 84515db4884b109b896ca11f0504e9cc 133 Pfam PF01850 PIN domain 2 108 2.1E-11 T 28-03-2018 IPR002716 PIN domain CP478_RS07655 84515db4884b109b896ca11f0504e9cc 133 Gene3D G3DSA:3.40.50.1010 1 123 8.5E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS16370 304a7e41b1cf53f21fcb7671da17de7d 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 62 260 1.2E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS16370 304a7e41b1cf53f21fcb7671da17de7d 265 Gene3D G3DSA:3.90.850.10 30 263 1.2E-84 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS16370 304a7e41b1cf53f21fcb7671da17de7d 265 Pfam PF10370 Domain of unknown function (DUF2437) 1 57 3.9E-16 T 28-03-2018 IPR018833 Domain of unknown function DUF2437 CP478_RS16370 304a7e41b1cf53f21fcb7671da17de7d 265 SUPERFAMILY SSF56529 53 260 1.23E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CP478_RS18775 8778b09891f762e3aa06fb8ad608c15c 178 Gene3D G3DSA:1.10.287.1060 19 103 4.4E-6 T 28-03-2018 CP478_RS18775 8778b09891f762e3aa06fb8ad608c15c 178 Pfam PF00823 PPE family 4 157 2.3E-51 T 28-03-2018 IPR000030 PPE family CP478_RS18775 8778b09891f762e3aa06fb8ad608c15c 178 SUPERFAMILY SSF140459 2 172 4.71E-53 T 28-03-2018 CP478_RS18575 75d0e7f5134c32977335d936e3b13d90 527 Gene3D G3DSA:3.30.70.270 40 99 2.3E-4 T 28-03-2018 CP478_RS18575 75d0e7f5134c32977335d936e3b13d90 527 Gene3D G3DSA:1.10.150.20 160 239 1.5E-8 T 28-03-2018 CP478_RS18575 75d0e7f5134c32977335d936e3b13d90 527 Pfam PF00817 impB/mucB/samB family 20 148 1.4E-10 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CP478_RS18575 75d0e7f5134c32977335d936e3b13d90 527 SUPERFAMILY SSF56672 7 231 1.33E-31 T 28-03-2018 CP478_RS02910 e9fac19ddb7f63c7568947d7cedede43 100 Pfam PF11829 Protein of unknown function (DUF3349) 4 91 1.1E-33 T 28-03-2018 IPR021784 Protein of unknown function DUF3349 CP478_RS00580 bc87c8d06ec7ead427f06a11d8788ce6 94 Gene3D G3DSA:2.30.170.40 2 65 9.3E-22 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00580 bc87c8d06ec7ead427f06a11d8788ce6 94 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.5E-21 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS00580 bc87c8d06ec7ead427f06a11d8788ce6 94 Pfam PF00830 Ribosomal L28 family 4 61 2.3E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS00580 bc87c8d06ec7ead427f06a11d8788ce6 94 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 70 19.954 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CP478_RS00580 bc87c8d06ec7ead427f06a11d8788ce6 94 SUPERFAMILY SSF143800 2 63 5.49E-21 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CP478_RS12055 b538de837743205c139fd2522328c08c 250 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 32 239 5.0E-92 T 28-03-2018 CP478_RS12055 b538de837743205c139fd2522328c08c 250 Pfam PF13829 Domain of unknown function (DUF4191) 23 241 6.5E-83 T 28-03-2018 IPR025445 Protein of unknown function DUF4191 CP478_RS06710 1c5f6b674ebe174a8f34ca31488e9f11 276 Gene3D G3DSA:3.40.50.1000 7 275 1.1E-39 T 28-03-2018 IPR023214 HAD-like domain CP478_RS06710 1c5f6b674ebe174a8f34ca31488e9f11 276 Pfam PF13344 Haloacid dehalogenase-like hydrolase 11 105 9.4E-22 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CP478_RS06710 1c5f6b674ebe174a8f34ca31488e9f11 276 Pfam PF13242 HAD-hyrolase-like 192 268 2.2E-18 T 28-03-2018 CP478_RS06710 1c5f6b674ebe174a8f34ca31488e9f11 276 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 241 3.5E-45 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CP478_RS06710 1c5f6b674ebe174a8f34ca31488e9f11 276 SUPERFAMILY SSF56784 10 271 3.01E-53 T 28-03-2018 IPR023214 HAD-like domain CP478_RS15030 5ace05b209bde6d3457677026d0f63d1 277 Pfam PF11248 Protein of unknown function (DUF3046) 228 268 7.6E-12 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 CP478_RS12285 c084aa1033fb05aa1afa147cd22137f8 353 Pfam PF13847 Methyltransferase domain 170 330 5.7E-26 T 28-03-2018 IPR025714 Methyltransferase domain CP478_RS12285 c084aa1033fb05aa1afa147cd22137f8 353 SUPERFAMILY SSF53335 157 348 1.88E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS12285 c084aa1033fb05aa1afa147cd22137f8 353 Gene3D G3DSA:3.40.50.150 116 347 7.4E-30 T 28-03-2018 CP478_RS12285 c084aa1033fb05aa1afa147cd22137f8 353 Gene3D G3DSA:1.10.10.10 4 109 1.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 42 257 7.7E-35 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 Gene3D G3DSA:3.40.710.10 8 290 1.7E-51 T 28-03-2018 CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 8.3E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 8.3E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 8.3E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CP478_RS15900 5e9f344adc1e0e24a7b39cdb347106c5 291 SUPERFAMILY SSF56601 9 280 1.44E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS14635 08994a27bdcc098dd57903d98e406edf 156 Pfam PF00583 Acetyltransferase (GNAT) family 36 131 7.9E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CP478_RS14635 08994a27bdcc098dd57903d98e406edf 156 Gene3D G3DSA:3.40.630.30 1 156 3.6E-35 T 28-03-2018 CP478_RS14635 08994a27bdcc098dd57903d98e406edf 156 SUPERFAMILY SSF55729 2 155 6.18E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS19625 8ea81487bd63a6dfdcfe6fab39750625 105 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 74 3.3E-18 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CP478_RS19625 8ea81487bd63a6dfdcfe6fab39750625 105 SUPERFAMILY SSF54909 2 98 1.26E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS19625 8ea81487bd63a6dfdcfe6fab39750625 105 Gene3D G3DSA:3.30.70.100 1 102 5.5E-28 T 28-03-2018 CP478_RS03410 4680d3b04b2f55c630883bbf2f500ea1 83 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 16 68 5.2E-20 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS14990 e4a0e2de074d09b831b6f7a00c42dfe8 174 Hamap MF_01114 Regulatory protein RecX [recX]. 12 168 14.027 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CP478_RS14990 e4a0e2de074d09b831b6f7a00c42dfe8 174 Gene3D G3DSA:1.10.10.10 63 108 4.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14990 e4a0e2de074d09b831b6f7a00c42dfe8 174 Gene3D G3DSA:1.10.10.10 8 62 7.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14990 e4a0e2de074d09b831b6f7a00c42dfe8 174 Pfam PF02631 RecX family 39 161 1.7E-23 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CP478_RS14990 e4a0e2de074d09b831b6f7a00c42dfe8 174 Gene3D G3DSA:1.10.10.10 113 166 2.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS05175 b75cc725feacc8aef222d42a63c0afb6 105 SUPERFAMILY SSF48600 22 86 2.44E-13 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS05175 b75cc725feacc8aef222d42a63c0afb6 105 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 28 101 2.0E-38 T 28-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal CP478_RS05175 b75cc725feacc8aef222d42a63c0afb6 105 SMART SM00830 33 95 1.6E-6 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS05175 b75cc725feacc8aef222d42a63c0afb6 105 Pfam PF01817 Chorismate mutase type II 33 85 2.4E-10 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS05175 b75cc725feacc8aef222d42a63c0afb6 105 Gene3D G3DSA:1.20.59.10 16 103 3.0E-16 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CP478_RS13110 4af10a762a987f9629c2c62b8b7e98d4 642 Gene3D G3DSA:1.50.10.10 235 581 1.9E-91 T 28-03-2018 CP478_RS13110 4af10a762a987f9629c2c62b8b7e98d4 642 Pfam PF00723 Glycosyl hydrolases family 15 255 566 6.4E-50 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CP478_RS13110 4af10a762a987f9629c2c62b8b7e98d4 642 SUPERFAMILY SSF48208 224 622 1.28E-97 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 962 999 2.7E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 880 917 8.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 923 960 1.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 1001 1040 6.5E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 808 846 2.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 348 386 4.4E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 358 396 1.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 278 314 2.8E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 235 272 3.0E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF01469 Pentapeptide repeats (8 copies) 318 356 2.1E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 SUPERFAMILY SSF140459 3 173 6.54E-58 T 28-03-2018 CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Pfam PF00823 PPE family 6 162 2.2E-57 T 28-03-2018 IPR000030 PPE family CP478_RS10430 b9c88e939edae04c9402f6caa21483f3 1459 Gene3D G3DSA:1.10.287.1060 21 107 9.0E-4 T 28-03-2018 CP478_RS05820 2db082277117e8c21ee652a5488e06ce 157 Gene3D G3DSA:3.30.530.20 7 155 2.8E-18 T 28-03-2018 IPR023393 START-like domain CP478_RS05820 2db082277117e8c21ee652a5488e06ce 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 34 155 1.8E-17 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS05820 2db082277117e8c21ee652a5488e06ce 157 SUPERFAMILY SSF55961 35 152 1.83E-16 T 28-03-2018 CP478_RS07740 8fd95a24140f75b651ca9ccfb3699bec 133 Pfam PF14031 Putative serine dehydratase domain 19 115 2.7E-20 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CP478_RS07740 8fd95a24140f75b651ca9ccfb3699bec 133 SMART SM01119 19 116 1.2E-36 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CP478_RS20330 1e90280b3eb100155f4e833ed3cb0cb1 435 Gene3D G3DSA:3.90.1150.10 283 415 7.6E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS20330 1e90280b3eb100155f4e833ed3cb0cb1 435 Gene3D G3DSA:3.40.640.10 58 282 2.4E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CP478_RS20330 1e90280b3eb100155f4e833ed3cb0cb1 435 SUPERFAMILY SSF53383 62 413 3.38E-37 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CP478_RS20330 1e90280b3eb100155f4e833ed3cb0cb1 435 Pfam PF12897 Alanine-glyoxylate amino-transferase 6 425 4.9E-181 T 28-03-2018 IPR024551 Aminotransferase, putative CP478_RS15180 864f4fdcc4ad2eca08a8d5a7ae048032 150 Gene3D G3DSA:3.40.50.360 2 149 3.8E-15 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS15180 864f4fdcc4ad2eca08a8d5a7ae048032 150 SUPERFAMILY SSF52218 3 148 1.93E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CP478_RS13235 34d4051ab3f91bf006f2fb7783132520 333 Pfam PF02371 Transposase IS116/IS110/IS902 family 169 255 1.7E-22 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CP478_RS18645 76d2bf45d86b19c91646edc29626fffc 295 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 269 4.7E-48 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CP478_RS18645 76d2bf45d86b19c91646edc29626fffc 295 Gene3D G3DSA:3.60.130.10 1 287 2.1E-68 T 28-03-2018 CP478_RS18645 76d2bf45d86b19c91646edc29626fffc 295 SUPERFAMILY SSF51197 5 284 2.47E-81 T 28-03-2018 CP478_RS10395 1d91826fb0c56c735851ca9acf981b8e 197 SUPERFAMILY SSF49777 55 195 1.57E-30 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS10395 1d91826fb0c56c735851ca9acf981b8e 197 Pfam PF01161 Phosphatidylethanolamine-binding protein 69 195 2.1E-21 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS10395 1d91826fb0c56c735851ca9acf981b8e 197 Gene3D G3DSA:3.90.280.10 39 197 2.8E-34 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS00065 05bb449b016eb4f5c3ea8e26abeaacae 141 Pfam PF10756 Bacterial PH domain 58 135 5.3E-22 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CP478_RS08270 71e6f213872e928f783443fcb4d97dcd 120 Pfam PF16363 GDP-mannose 4,6 dehydratase 34 72 2.1E-9 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS01325 4d1d192d62f9eb41133ccde41dba5a58 162 SUPERFAMILY SSF50475 9 155 1.23E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS01325 4d1d192d62f9eb41133ccde41dba5a58 162 Pfam PF01613 Flavin reductase like domain 17 159 3.6E-25 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS01325 4d1d192d62f9eb41133ccde41dba5a58 162 SMART SM00903 16 159 1.3E-38 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CP478_RS01325 4d1d192d62f9eb41133ccde41dba5a58 162 Gene3D G3DSA:2.30.110.10 4 162 1.4E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 3.7E-12 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 PRINTS PR00758 Arsenical pump membrane protein signature 396 420 3.7E-12 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 PRINTS PR00758 Arsenical pump membrane protein signature 274 298 3.7E-12 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 3.7E-12 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 3.7E-12 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CP478_RS14720 82867198c35d95c567d0ae442be802aa 429 Pfam PF03600 Citrate transporter 13 367 2.4E-53 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CP478_RS05875 9a2d68e9b27c922fe38f2eca7235a5d6 345 Gene3D G3DSA:3.90.226.10 2 330 8.7E-87 T 28-03-2018 CP478_RS05875 9a2d68e9b27c922fe38f2eca7235a5d6 345 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 336 5.3E-118 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CP478_RS05875 9a2d68e9b27c922fe38f2eca7235a5d6 345 SUPERFAMILY SSF52096 249 319 1.66E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS05875 9a2d68e9b27c922fe38f2eca7235a5d6 345 SUPERFAMILY SSF52096 5 197 1.66E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 Gene3D G3DSA:1.50.10.20 188 468 2.4E-20 T 28-03-2018 CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 Gene3D G3DSA:1.50.10.20 9 116 4.4E-6 T 28-03-2018 CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 339 422 2.1E-7 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 SUPERFAMILY SSF48239 17 100 2.15E-7 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 SUPERFAMILY SSF48239 216 480 5.3E-26 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CP478_RS18495 b3121ce8fdc69fdef4afb5bf013d421d 501 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 40 56 0.018 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 CP478_RS20305 f225a85fbea152fb7932e6fe4efffb9c 241 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 29 230 3.4E-31 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CP478_RS20305 f225a85fbea152fb7932e6fe4efffb9c 241 SUPERFAMILY SSF53187 26 234 3.3E-33 T 28-03-2018 CP478_RS20305 f225a85fbea152fb7932e6fe4efffb9c 241 SMART SM00646 110 231 2.2E-32 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CP478_RS20305 f225a85fbea152fb7932e6fe4efffb9c 241 Gene3D G3DSA:3.40.630.40 8 241 7.9E-46 T 28-03-2018 CP478_RS02745 79dc1c4765f44ce140021e1f0a8239ab 182 PIRSF PIRSF026610 1 182 5.3E-104 T 28-03-2018 IPR016844 Uncharacterised conserved protein UCP026610 CP478_RS04780 6914c22abff4676de8dde519f93638a9 548 Pfam PF07690 Major Facilitator Superfamily 122 484 4.3E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS04780 6914c22abff4676de8dde519f93638a9 548 SUPERFAMILY SSF103473 113 511 5.76E-14 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS04780 6914c22abff4676de8dde519f93638a9 548 Gene3D G3DSA:1.20.1250.20 341 518 3.6E-7 T 28-03-2018 CP478_RS04780 6914c22abff4676de8dde519f93638a9 548 Gene3D G3DSA:1.20.1250.20 107 306 5.2E-6 T 28-03-2018 CP478_RS10005 9ce70f94e074b6b2c71b2cb060f0d2dd 87 Gene3D G3DSA:1.10.1220.10 1 43 1.8E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS15450 e6a7ffddbfe1a98c313f3af4500885d7 181 Pfam PF08819 Domain of unknown function (DUF1802) 4 174 1.6E-60 T 28-03-2018 IPR014923 Protein of unknown function DUF1802 CP478_RS15450 e6a7ffddbfe1a98c313f3af4500885d7 181 PIRSF PIRSF018957 1 181 7.2E-96 T 28-03-2018 IPR008307 Uncharacterised conserved protein UCP018957 CP478_RS12355 eef0f9d339750f67c4b2d41a9a3d5fee 122 Pfam PF02656 Domain of unknown function (DUF202) 17 83 2.9E-17 T 28-03-2018 IPR003807 Domain of unknown function DUF202 CP478_RS15945 516d29aeabb349f574d92e6c3bcf5e00 477 TIGRFAM TIGR00836 amt: ammonium transporter 14 441 1.3E-147 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CP478_RS15945 516d29aeabb349f574d92e6c3bcf5e00 477 SUPERFAMILY SSF111352 11 422 1.31E-118 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CP478_RS15945 516d29aeabb349f574d92e6c3bcf5e00 477 Pfam PF00909 Ammonium Transporter Family 16 441 3.2E-138 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CP478_RS15945 516d29aeabb349f574d92e6c3bcf5e00 477 Gene3D G3DSA:1.10.3430.10 7 422 4.6E-127 T 28-03-2018 CP478_RS15945 516d29aeabb349f574d92e6c3bcf5e00 477 ProSitePatterns PS01219 Ammonium transporters signature. 191 216 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CP478_RS09900 7c6f02c850721c8a3aa64fe4f8cce588 498 Pfam PF00934 PE family 1 93 4.9E-36 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09900 7c6f02c850721c8a3aa64fe4f8cce588 498 SUPERFAMILY SSF140459 8 84 2.38E-26 T 28-03-2018 CP478_RS18570 64715200271a1abcb9587fc3f672188d 308 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 295 2.7E-73 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CP478_RS18570 64715200271a1abcb9587fc3f672188d 308 SUPERFAMILY SSF53590 4 302 8.5E-78 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CP478_RS18570 64715200271a1abcb9587fc3f672188d 308 Gene3D G3DSA:3.90.245.10 2 304 8.0E-87 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CP478_RS06830 a1bbfa86ac658e2542dc1daa3e8aee25 89 SUPERFAMILY SSF143120 1 82 1.31E-21 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS06830 a1bbfa86ac658e2542dc1daa3e8aee25 89 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 55 4.1E-16 T 28-03-2018 CP478_RS06830 a1bbfa86ac658e2542dc1daa3e8aee25 89 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 73 1.3E-21 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS06830 a1bbfa86ac658e2542dc1daa3e8aee25 89 Gene3D G3DSA:3.40.1620.10 1 51 3.4E-18 T 28-03-2018 CP478_RS06235 81ebade67a6fd87b0205e6c27dd0455a 166 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 73 163 8.1E-27 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 4.5E-116 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 SUPERFAMILY SSF55205 4 416 1.11E-131 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 Gene3D G3DSA:3.65.10.10 22 220 4.8E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 40.534 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 7.3E-171 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CP478_RS07200 7bbffba923c497cca8da1ac2100aebe3 418 Gene3D G3DSA:3.65.10.10 221 418 6.7E-45 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CP478_RS13850 bc97eb9fa6abdbfa37e7609cb80279c0 133 Gene3D G3DSA:3.40.50.1010 1 123 4.7E-9 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13850 bc97eb9fa6abdbfa37e7609cb80279c0 133 Pfam PF01850 PIN domain 27 119 1.5E-5 T 28-03-2018 IPR002716 PIN domain CP478_RS13850 bc97eb9fa6abdbfa37e7609cb80279c0 133 SUPERFAMILY SSF88723 1 120 1.82E-8 T 28-03-2018 IPR029060 PIN domain-like CP478_RS13850 bc97eb9fa6abdbfa37e7609cb80279c0 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 124 12.336 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS05865 988db1d61a41260bfa320effc6ad136d 587 PIRSF PIRSF007542 1 587 4.8E-253 T 28-03-2018 IPR012037 Alpha/beta-hydrolase family CP478_RS05865 988db1d61a41260bfa320effc6ad136d 587 Pfam PF10081 Alpha/beta-hydrolase family 287 574 1.7E-131 T 28-03-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain CP478_RS05865 988db1d61a41260bfa320effc6ad136d 587 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 63 270 9.3E-73 T 28-03-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain CP478_RS19350 39e7485eacc622c85d28d85bfbb658bb 386 SUPERFAMILY SSF53901 267 378 8.96E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19350 39e7485eacc622c85d28d85bfbb658bb 386 SUPERFAMILY SSF53901 4 232 1.86E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19350 39e7485eacc622c85d28d85bfbb658bb 386 Gene3D G3DSA:3.40.47.10 3 136 1.5E-6 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19350 39e7485eacc622c85d28d85bfbb658bb 386 Gene3D G3DSA:3.40.47.10 146 384 3.7E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19350 39e7485eacc622c85d28d85bfbb658bb 386 PIRSF PIRSF000429 3 340 4.2E-21 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS14345 904cc52b41d083d4694749ff12ce8d42 225 Gene3D G3DSA:1.10.10.10 1 77 1.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS14345 904cc52b41d083d4694749ff12ce8d42 225 SUPERFAMILY SSF46785 2 194 3.93E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18170 2bea7ddee82e0abf1e80108b5d1b7476 144 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 25 133 3.4E-28 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18170 2bea7ddee82e0abf1e80108b5d1b7476 144 Gene3D G3DSA:1.20.1300.10 11 140 5.9E-25 T 28-03-2018 CP478_RS18170 2bea7ddee82e0abf1e80108b5d1b7476 144 SUPERFAMILY SSF81343 14 133 2.18E-28 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS18170 2bea7ddee82e0abf1e80108b5d1b7476 144 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 18 128 1.3E-23 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 Gene3D G3DSA:3.30.559.10 22 219 6.1E-9 T 28-03-2018 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 Pfam PF06974 Protein of unknown function (DUF1298) 341 486 6.1E-30 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 SUPERFAMILY SSF52777 266 487 9.0E-5 T 28-03-2018 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 32 296 1.2E-93 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 SUPERFAMILY SSF52777 95 188 1.04E-8 T 28-03-2018 CP478_RS04885 cd7b3aabe3326c59a62702405db47a92 505 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 32 488 7.0E-154 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS06225 42ab4a4e844ab6b35424096b3fa7914d 113 Gene3D G3DSA:1.10.12.10 7 63 4.8E-4 T 28-03-2018 IPR014748 Crontonase, C-terminal CP478_RS19285 bfc2ee2f21efcd3b3f4a81c750237292 65 Gene3D G3DSA:1.10.260.40 26 64 7.1E-4 T 28-03-2018 CP478_RS20080 77ddd045f56391763f027c46035b6807 151 Gene3D G3DSA:3.30.1330.40 1 151 3.7E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CP478_RS20080 77ddd045f56391763f027c46035b6807 151 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 150 2.6E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CP478_RS20080 77ddd045f56391763f027c46035b6807 151 SUPERFAMILY SSF55298 2 150 1.18E-54 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CP478_RS21330 7d9c324cfeb7b5ee0a66581473b9c423 90 Gene3D G3DSA:1.10.287.1060 1 90 1.3E-10 T 28-03-2018 CP478_RS21330 7d9c324cfeb7b5ee0a66581473b9c423 90 SUPERFAMILY SSF140453 1 90 1.31E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21330 7d9c324cfeb7b5ee0a66581473b9c423 90 Pfam PF06013 Proteins of 100 residues with WXG 1 80 2.8E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS03125 1e9478bb3209f712d7a91de245ef8cc7 228 Pfam PF10738 Probable lipoprotein LpqN 57 227 5.6E-59 T 28-03-2018 IPR019674 Lipoprotein LpqT, predicted CP478_RS03125 1e9478bb3209f712d7a91de245ef8cc7 228 Gene3D G3DSA:3.40.1000.10 85 228 5.0E-16 T 28-03-2018 CP478_RS20930 b0e89927a4b9856fcb66b2314bc0eea6 191 Gene3D G3DSA:3.40.50.150 5 189 2.8E-25 T 28-03-2018 CP478_RS20930 b0e89927a4b9856fcb66b2314bc0eea6 191 SUPERFAMILY SSF53335 16 175 4.58E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20930 b0e89927a4b9856fcb66b2314bc0eea6 191 Pfam PF08241 Methyltransferase domain 39 133 2.0E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS05880 989c82b7cf3fe0f1b5ff0a40c0e23518 278 Pfam PF12811 Bax inhibitor 1 like 25 277 1.3E-85 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CP478_RS05880 989c82b7cf3fe0f1b5ff0a40c0e23518 278 PIRSF PIRSF009160 1 278 1.5E-94 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CP478_RS13870 9b296a37f0238e0290bed26147ece980 74 Gene3D G3DSA:1.10.1220.10 1 40 1.2E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS04755 6eac57aae6091d86a08e7b0e1306cad5 609 SUPERFAMILY SSF140459 8 84 9.68E-26 T 28-03-2018 CP478_RS04755 6eac57aae6091d86a08e7b0e1306cad5 609 Pfam PF00934 PE family 1 93 7.1E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS11530 dc8c3b6da84bfc871e36b047d60302f2 278 Pfam PF12705 PD-(D/E)XK nuclease superfamily 14 260 5.8E-38 T 28-03-2018 CP478_RS11530 dc8c3b6da84bfc871e36b047d60302f2 278 SUPERFAMILY SSF52980 36 194 2.79E-7 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CP478_RS11530 dc8c3b6da84bfc871e36b047d60302f2 278 Gene3D G3DSA:3.90.320.10 2 206 2.7E-21 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CP478_RS17130 88ede211b9a8346bc691afd410a97d27 110 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 1 86 1.3E-12 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CP478_RS17130 88ede211b9a8346bc691afd410a97d27 110 SUPERFAMILY SSF50475 2 89 8.29E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS17130 88ede211b9a8346bc691afd410a97d27 110 Gene3D G3DSA:2.30.110.10 1 97 1.3E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS14630 ea2124bf87e67159eed83e3f281cb404 173 Gene3D G3DSA:2.60.40.1240 29 173 9.2E-22 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 Gene3D G3DSA:1.10.630.10 1 398 6.7E-62 T 28-03-2018 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 SUPERFAMILY SSF48264 9 398 9.69E-79 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 Pfam PF00067 Cytochrome P450 206 367 5.0E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 337 346 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 270 281 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 87 98 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 288 315 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 316 331 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS17080 65f0cadf1ffd9f3f75ec4c320de5962b 400 PRINTS PR00359 B-class P450 signature 189 211 9.5E-30 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CP478_RS11570 23b81da4423e137772ae4919ab073261 489 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CP478_RS11570 23b81da4423e137772ae4919ab073261 489 Pfam PF00324 Amino acid permease 26 444 7.6E-104 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CP478_RS11570 23b81da4423e137772ae4919ab073261 489 PIRSF PIRSF006060 6 474 1.4E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS11640 2322c4934a1ec6ab642d84492a96b1d6 176 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 171 5.7E-38 T 28-03-2018 IPR005247 YbhB/YbcL CP478_RS11640 2322c4934a1ec6ab642d84492a96b1d6 176 SUPERFAMILY SSF49777 17 174 1.83E-47 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS11640 2322c4934a1ec6ab642d84492a96b1d6 176 Gene3D G3DSA:3.90.280.10 1 176 2.1E-51 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS11640 2322c4934a1ec6ab642d84492a96b1d6 176 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 173 3.9E-34 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS21335 86269c73ba3b375afe69e8b42894c2f2 103 Gene3D G3DSA:1.10.287.1060 3 100 2.0E-16 T 28-03-2018 CP478_RS21335 86269c73ba3b375afe69e8b42894c2f2 103 SUPERFAMILY SSF140453 6 99 2.75E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21335 86269c73ba3b375afe69e8b42894c2f2 103 Pfam PF06013 Proteins of 100 residues with WXG 7 90 1.9E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS21335 86269c73ba3b375afe69e8b42894c2f2 103 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 95 8.0E-15 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS19640 b166546424aae2fd6f1fb495b4f6b31f 439 Pfam PF00934 PE family 1 93 1.8E-36 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19640 b166546424aae2fd6f1fb495b4f6b31f 439 SUPERFAMILY SSF140459 8 84 2.41E-26 T 28-03-2018 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 Gene3D G3DSA:3.40.50.980 197 372 1.2E-24 T 28-03-2018 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 Gene3D G3DSA:3.40.50.980 24 196 1.1E-26 T 28-03-2018 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 Gene3D G3DSA:3.30.300.30 491 619 7.2E-12 T 28-03-2018 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 Pfam PF00501 AMP-binding enzyme 34 497 8.1E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 Gene3D G3DSA:2.30.38.10 401 490 1.5E-15 T 28-03-2018 CP478_RS20760 af0be5a1fd7b781526aecdf2c2f3450a 637 SUPERFAMILY SSF56801 27 621 3.14E-85 T 28-03-2018 CP478_RS05330 3761e24b98df76d4ec4150def28f1f20 923 Gene3D G3DSA:2.40.70.10 664 806 1.8E-6 T 28-03-2018 IPR021109 Aspartic peptidase domain CP478_RS05330 3761e24b98df76d4ec4150def28f1f20 923 Pfam PF00934 PE family 1 91 8.9E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS05330 3761e24b98df76d4ec4150def28f1f20 923 SUPERFAMILY SSF140459 8 83 2.62E-22 T 28-03-2018 CP478_RS12745 1da882d4dd54c10bf36fb3bf5c2b0399 372 Gene3D G3DSA:3.40.109.10 102 355 1.4E-14 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CP478_RS12745 1da882d4dd54c10bf36fb3bf5c2b0399 372 Gene3D G3DSA:3.40.109.30 11 94 4.5E-4 T 28-03-2018 CP478_RS15670 822204f639f57b5d7191e5820ce0d29f 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 85 3.2E-13 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CP478_RS15670 822204f639f57b5d7191e5820ce0d29f 87 SUPERFAMILY SSF143011 3 84 7.46E-18 T 28-03-2018 IPR035095 Toxin RelE-like domain CP478_RS15670 822204f639f57b5d7191e5820ce0d29f 87 Gene3D G3DSA:3.30.2310.20 1 87 1.2E-22 T 28-03-2018 CP478_RS20750 3a3697d7c00668cb1728d116609d0fbb 522 Gene3D G3DSA:3.90.226.10 259 517 8.4E-64 T 28-03-2018 CP478_RS20750 3a3697d7c00668cb1728d116609d0fbb 522 SUPERFAMILY SSF52096 245 513 1.66E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS20750 3a3697d7c00668cb1728d116609d0fbb 522 Pfam PF01039 Carboxyl transferase domain 39 519 8.0E-137 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CP478_RS20750 3a3697d7c00668cb1728d116609d0fbb 522 SUPERFAMILY SSF52096 13 261 1.54E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS20750 3a3697d7c00668cb1728d116609d0fbb 522 Gene3D G3DSA:3.90.226.10 3 258 1.4E-62 T 28-03-2018 CP478_RS12615 330caf4a842da75f698bbaf520e40b2c 284 SUPERFAMILY SSF69118 137 261 7.05E-18 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS12615 330caf4a842da75f698bbaf520e40b2c 284 Gene3D G3DSA:1.20.1290.10 127 271 5.6E-14 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CP478_RS04940 78bc6158e03f08557fc918cd8634140d 372 Gene3D G3DSA:3.60.15.10 91 363 2.1E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04940 78bc6158e03f08557fc918cd8634140d 372 Pfam PF12706 Beta-lactamase superfamily domain 123 321 4.6E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04940 78bc6158e03f08557fc918cd8634140d 372 SUPERFAMILY SSF56281 107 182 3.28E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04940 78bc6158e03f08557fc918cd8634140d 372 SUPERFAMILY SSF56281 210 364 3.28E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS04940 78bc6158e03f08557fc918cd8634140d 372 PIRSF PIRSF038896 1 371 7.3E-114 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CP478_RS03280 e1d5396790529d6781e423b4dd5a5916 73 Pfam PF16277 Domain of unknown function (DUF4926) 4 59 1.1E-21 T 28-03-2018 IPR032568 Protein of unknown function DUF4926 CP478_RS18000 be514f89fe5bafb5e22df64398c46288 143 Pfam PF02657 Fe-S metabolism associated domain 16 137 2.1E-29 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like CP478_RS18000 be514f89fe5bafb5e22df64398c46288 143 SUPERFAMILY SSF82649 4 140 5.13E-29 T 28-03-2018 CP478_RS18000 be514f89fe5bafb5e22df64398c46288 143 Gene3D G3DSA:3.90.1010.10 1 142 2.6E-41 T 28-03-2018 CP478_RS15430 84094cafbe48aafc62e3eda82061adfd 236 Pfam PF03787 RAMP superfamily 13 208 1.2E-13 T 28-03-2018 IPR005537 CRISPR type III-associated RAMP protein CP478_RS15430 84094cafbe48aafc62e3eda82061adfd 236 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 6 209 4.4E-73 T 28-03-2018 IPR013412 CRISPR-associated RAMP Csm3 CP478_RS02190 7f61fc70338fea7d9d06e135ac605a4b 328 SUPERFAMILY SSF53850 82 312 5.96E-55 T 28-03-2018 CP478_RS02190 7f61fc70338fea7d9d06e135ac605a4b 328 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 94 313 5.0E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CP478_RS02190 7f61fc70338fea7d9d06e135ac605a4b 328 SMART SM00062 93 315 2.3E-74 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CP478_RS02190 7f61fc70338fea7d9d06e135ac605a4b 328 Gene3D G3DSA:3.40.190.10 83 191 4.5E-22 T 28-03-2018 CP478_RS02190 7f61fc70338fea7d9d06e135ac605a4b 328 Gene3D G3DSA:3.40.190.10 192 277 2.3E-21 T 28-03-2018 CP478_RS18630 2e28174ca09a7338f5f5e187e9fcf96e 533 SUPERFAMILY SSF51905 8 95 1.62E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18630 2e28174ca09a7338f5f5e187e9fcf96e 533 SUPERFAMILY SSF51905 136 272 1.62E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18630 2e28174ca09a7338f5f5e187e9fcf96e 533 Pfam PF13454 FAD-NAD(P)-binding 19 205 1.7E-9 T 28-03-2018 CP478_RS18630 2e28174ca09a7338f5f5e187e9fcf96e 533 Gene3D G3DSA:3.50.50.60 244 528 0.001 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS18630 2e28174ca09a7338f5f5e187e9fcf96e 533 Gene3D G3DSA:3.50.50.60 12 227 1.8E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS17215 50e74d2826d7f10e90d57934a18365d7 133 SMART SM00448 8 124 0.0086 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CP478_RS17215 50e74d2826d7f10e90d57934a18365d7 133 SUPERFAMILY SSF52172 8 129 2.72E-9 T 28-03-2018 IPR011006 CheY-like superfamily CP478_RS17215 50e74d2826d7f10e90d57934a18365d7 133 Gene3D G3DSA:3.40.50.2300 2 133 1.0E-12 T 28-03-2018 CP478_RS12700 292457f500fcc3b4602fb03509c5036a 515 Gene3D G3DSA:1.20.1250.20 250 478 4.8E-15 T 28-03-2018 CP478_RS12700 292457f500fcc3b4602fb03509c5036a 515 SUPERFAMILY SSF103473 50 474 8.5E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12700 292457f500fcc3b4602fb03509c5036a 515 Gene3D G3DSA:1.20.1250.20 45 245 2.0E-13 T 28-03-2018 CP478_RS12700 292457f500fcc3b4602fb03509c5036a 515 Pfam PF07690 Major Facilitator Superfamily 62 403 2.7E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS00130 f4fd917d9da6be3fca754952779e0d8b 139 Pfam PF02467 Transcription factor WhiB 12 83 2.8E-13 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS00130 f4fd917d9da6be3fca754952779e0d8b 139 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 88 15.565 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 114 137 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 93 106 2.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 Gene3D G3DSA:1.10.357.10 138 274 9.5E-14 T 28-03-2018 CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 Pfam PF00440 Bacterial regulatory proteins, tetR family 93 139 7.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 SUPERFAMILY SSF46689 80 162 1.15E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 SUPERFAMILY SSF48498 188 279 6.36E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS00780 a7866d98438092a192b3614ba65a0fe8 280 Gene3D G3DSA:1.10.10.60 64 137 2.0E-19 T 28-03-2018 CP478_RS09160 8b8394f3737ef0fbc45a19f69bd03a00 182 Gene3D G3DSA:3.40.30.10 26 177 6.2E-29 T 28-03-2018 CP478_RS09160 8b8394f3737ef0fbc45a19f69bd03a00 182 SUPERFAMILY SSF52833 47 179 1.28E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS09160 8b8394f3737ef0fbc45a19f69bd03a00 182 ProSitePatterns PS00194 Thioredoxin family active site. 75 93 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CP478_RS09160 8b8394f3737ef0fbc45a19f69bd03a00 182 Pfam PF00578 AhpC/TSA family 53 161 5.4E-14 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS14080 bc40d6d51d59cc2716e04b921b2504fb 341 Gene3D G3DSA:3.40.390.10 80 262 3.6E-16 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CP478_RS14080 bc40d6d51d59cc2716e04b921b2504fb 341 Pfam PF15887 Putative zinc-binding metallo-peptidase 88 323 3.1E-100 T 28-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CP478_RS14080 bc40d6d51d59cc2716e04b921b2504fb 341 Pfam PF10005 zinc-ribbon domain 4 80 3.7E-17 T 28-03-2018 IPR011201 Zinc-ribbon domain, bacteria CP478_RS14080 bc40d6d51d59cc2716e04b921b2504fb 341 PIRSF PIRSF012641 1 340 4.5E-163 T 28-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CP478_RS00285 50c322ba87f86686e7b29894bbd51554 212 SUPERFAMILY SSF52317 1 188 1.9E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS00285 50c322ba87f86686e7b29894bbd51554 212 Pfam PF01965 DJ-1/PfpI family 2 165 3.7E-25 T 28-03-2018 IPR002818 DJ-1/PfpI CP478_RS00285 50c322ba87f86686e7b29894bbd51554 212 Gene3D G3DSA:3.40.50.880 1 211 2.1E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS08960 08cc79f9cfdf3b373ddea26a5811c290 264 Gene3D G3DSA:3.60.15.10 60 262 9.9E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS08960 08cc79f9cfdf3b373ddea26a5811c290 264 SMART SM00849 75 243 5.7E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS08960 08cc79f9cfdf3b373ddea26a5811c290 264 SUPERFAMILY SSF56281 70 260 2.66E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS08960 08cc79f9cfdf3b373ddea26a5811c290 264 Pfam PF00753 Metallo-beta-lactamase superfamily 72 224 4.6E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 PRINTS PR01713 Nucleotide sugar epimerase signature 270 285 2.0E-5 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 PRINTS PR01713 Nucleotide sugar epimerase signature 310 327 2.0E-5 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 PRINTS PR01713 Nucleotide sugar epimerase signature 244 259 2.0E-5 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 Gene3D G3DSA:3.40.50.720 1 217 9.1E-27 T 28-03-2018 CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 Gene3D G3DSA:3.90.25.10 218 342 5.6E-27 T 28-03-2018 CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 SUPERFAMILY SSF51735 1 121 1.59E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 SUPERFAMILY SSF51735 158 340 1.59E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS02875 6abe2f0e3daca5ea51d0ca20c54c1cdb 346 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 267 4.9E-40 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CP478_RS08975 2da656e9fad828d21ae9952113bd088b 489 Pfam PF00756 Putative esterase 200 392 8.9E-11 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS08975 2da656e9fad828d21ae9952113bd088b 489 SUPERFAMILY SSF53474 398 467 2.86E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS08975 2da656e9fad828d21ae9952113bd088b 489 SUPERFAMILY SSF53474 174 370 2.86E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS08975 2da656e9fad828d21ae9952113bd088b 489 Gene3D G3DSA:3.40.50.1820 173 469 1.7E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 204 239 3.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 26 64 1.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 95 131 7.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 174 211 6.8E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 7 45 3.2E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 133 172 6.4E-10 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS12835 ded6af14fa81c3a6b1e384664c8d0b20 354 Pfam PF01469 Pentapeptide repeats (8 copies) 52 89 6.9E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS13930 de612a10f92821f86004c169c1e3b433 403 Gene3D G3DSA:3.40.50.1820 26 371 2.6E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS13930 de612a10f92821f86004c169c1e3b433 403 Pfam PF06259 Alpha/beta hydrolase 169 349 1.1E-76 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CP478_RS13930 de612a10f92821f86004c169c1e3b433 403 SUPERFAMILY SSF53474 232 341 1.62E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00355 1fd38edf0605701b6f2e3faa9d613eb4 979 Hamap MF_01600 UPF0182 protein . 11 906 17.921 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CP478_RS00355 1fd38edf0605701b6f2e3faa9d613eb4 979 Pfam PF03699 Uncharacterised protein family (UPF0182) 25 819 5.0E-272 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CP478_RS02995 56108c1fdf6fd66e3e986f8eeac3dcb7 241 SUPERFAMILY SSF53335 42 211 7.32E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02995 56108c1fdf6fd66e3e986f8eeac3dcb7 241 Gene3D G3DSA:3.40.50.150 11 207 3.5E-27 T 28-03-2018 CP478_RS02995 56108c1fdf6fd66e3e986f8eeac3dcb7 241 Pfam PF13847 Methyltransferase domain 65 169 1.6E-18 T 28-03-2018 IPR025714 Methyltransferase domain CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 191 206 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 Pfam PF00135 Carboxylesterase family 19 495 4.0E-95 T 28-03-2018 IPR002018 Carboxylesterase, type B CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 SUPERFAMILY SSF53474 16 506 5.36E-116 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 113 128 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 Gene3D G3DSA:3.40.50.1820 7 509 5.8E-124 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS11155 bf71ccd296753c6b7219fb60a71b9ac9 511 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 92 102 - T 28-03-2018 IPR019819 Carboxylesterase type B, conserved site CP478_RS09360 b0ebf282a617aff26d775cb628c8a760 276 Gene3D G3DSA:3.50.30.50 12 265 1.0E-66 T 28-03-2018 CP478_RS09360 b0ebf282a617aff26d775cb628c8a760 276 Pfam PF04199 Putative cyclase 17 168 9.8E-35 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CP478_RS09360 b0ebf282a617aff26d775cb628c8a760 276 SUPERFAMILY SSF102198 207 262 7.19E-57 T 28-03-2018 CP478_RS09360 b0ebf282a617aff26d775cb628c8a760 276 SUPERFAMILY SSF102198 14 169 7.19E-57 T 28-03-2018 CP478_RS14025 59e8a9f77b1631b51478590a74d7881d 236 Gene3D G3DSA:3.30.70.100 23 129 3.4E-6 T 28-03-2018 CP478_RS14025 59e8a9f77b1631b51478590a74d7881d 236 Gene3D G3DSA:3.30.70.100 130 233 2.8E-4 T 28-03-2018 CP478_RS14025 59e8a9f77b1631b51478590a74d7881d 236 SUPERFAMILY SSF54909 34 121 1.07E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS05720 76c45e8a98675a863f6ec473cbd41b24 207 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 18 66 2.4E-13 T 28-03-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 Pfam PF00934 PE family 1 93 1.4E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 PRINTS PR01228 Eggshell protein signature 402 420 3.0E-5 T 28-03-2018 CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 PRINTS PR01228 Eggshell protein signature 322 337 3.0E-5 T 28-03-2018 CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 PRINTS PR01228 Eggshell protein signature 245 256 3.0E-5 T 28-03-2018 CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 PRINTS PR01228 Eggshell protein signature 353 363 3.0E-5 T 28-03-2018 CP478_RS10010 807a5e04fc070514895a0b41d9d95467 515 SUPERFAMILY SSF140459 8 84 1.41E-25 T 28-03-2018 CP478_RS00465 b4dd647ad6143ce65ab4a7fb1ca37c76 640 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 205 229 9.5E-9 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00465 b4dd647ad6143ce65ab4a7fb1ca37c76 640 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 162 9.5E-9 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00465 b4dd647ad6143ce65ab4a7fb1ca37c76 640 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 356 382 9.5E-9 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS00465 b4dd647ad6143ce65ab4a7fb1ca37c76 640 Pfam PF00361 Proton-conducting membrane transporter 101 384 1.4E-52 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS18815 ff5b16fdd9e1713d3a1609bacf8efcb8 158 Pfam PF10708 Protein of unknown function (DUF2510) 129 156 9.4E-9 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 CP478_RS13665 a4a5aee563096aabf3bd65c367535624 185 Pfam PF01575 MaoC like domain 39 159 1.8E-28 T 28-03-2018 IPR002539 MaoC-like domain CP478_RS13665 a4a5aee563096aabf3bd65c367535624 185 SUPERFAMILY SSF54637 29 179 4.8E-46 T 28-03-2018 IPR029069 HotDog domain CP478_RS13665 a4a5aee563096aabf3bd65c367535624 185 Gene3D G3DSA:3.10.129.10 22 180 1.7E-36 T 28-03-2018 CP478_RS13430 dbe0655f5f924a43d08c5c33a3ad8687 302 Gene3D G3DSA:3.20.20.330 1 302 5.1E-95 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS13430 dbe0655f5f924a43d08c5c33a3ad8687 302 Pfam PF02574 Homocysteine S-methyltransferase 9 294 9.8E-75 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS13430 dbe0655f5f924a43d08c5c33a3ad8687 302 PIRSF PIRSF037505 2 216 1.0E-9 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CP478_RS13430 dbe0655f5f924a43d08c5c33a3ad8687 302 PIRSF PIRSF037505 254 302 0.23 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CP478_RS13430 dbe0655f5f924a43d08c5c33a3ad8687 302 SUPERFAMILY SSF82282 2 300 1.44E-80 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CP478_RS08840 309fedd8efa368b783d51ecaf404421f 132 Pfam PF10825 Protein of unknown function (DUF2752) 41 88 9.0E-19 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 CP478_RS07560 0eb3a803152ead2605d9932fac5c838a 193 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 13 193 35.951 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CP478_RS07560 0eb3a803152ead2605d9932fac5c838a 193 Gene3D G3DSA:3.40.50.2020 9 193 3.4E-30 T 28-03-2018 CP478_RS07560 0eb3a803152ead2605d9932fac5c838a 193 Pfam PF00156 Phosphoribosyl transferase domain 25 163 2.2E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CP478_RS07560 0eb3a803152ead2605d9932fac5c838a 193 SUPERFAMILY SSF53271 14 187 4.42E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS11440 0bcf379bbae2fdc329517e6d9f6d7258 238 Pfam PF04434 SWIM zinc finger 101 126 1.3E-6 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CP478_RS08175 d9dcf7492b98727494b614198190c46b 252 Pfam PF09335 SNARE associated Golgi protein 84 200 4.2E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CP478_RS01490 9f443715b73e9c055ece017bc54b6078 142 SUPERFAMILY SSF88723 1 138 3.08E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01490 9f443715b73e9c055ece017bc54b6078 142 TIGRFAM TIGR00028 Mtu_PIN_fam: toxin-antitoxin system PIN domain toxin 1 141 1.4E-49 T 28-03-2018 IPR006226 PIN domain toxin GO:0016788 CP478_RS01490 9f443715b73e9c055ece017bc54b6078 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 139 17.554 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS01490 9f443715b73e9c055ece017bc54b6078 142 Gene3D G3DSA:3.40.50.1010 1 142 1.7E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01490 9f443715b73e9c055ece017bc54b6078 142 Pfam PF01850 PIN domain 3 133 2.8E-11 T 28-03-2018 IPR002716 PIN domain CP478_RS14845 31fa179b39757c4a5d56122cef971e88 82 Pfam PF11238 Protein of unknown function (DUF3039) 24 79 1.6E-28 T 28-03-2018 IPR021400 Protein of unknown function DUF3039 CP478_RS10360 0e478ccf3949db060ebb47bf2d081ae3 134 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 119 8.0E-30 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CP478_RS09755 4bbd1814e2b792fc7ed2123eb96e169e 99 Gene3D G3DSA:1.10.287.1060 1 99 0.001 T 28-03-2018 CP478_RS09755 4bbd1814e2b792fc7ed2123eb96e169e 99 SUPERFAMILY SSF140459 8 83 1.12E-25 T 28-03-2018 CP478_RS09755 4bbd1814e2b792fc7ed2123eb96e169e 99 Pfam PF00934 PE family 1 93 3.3E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06315 abb66990bc69936783a5f75ebb39c764 237 Pfam PF02146 Sir2 family 8 184 1.7E-54 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CP478_RS06315 abb66990bc69936783a5f75ebb39c764 237 SUPERFAMILY SSF52467 2 232 1.85E-77 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS06315 abb66990bc69936783a5f75ebb39c764 237 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 1 234 60.674 T 28-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 CP478_RS06315 abb66990bc69936783a5f75ebb39c764 237 Gene3D G3DSA:3.40.50.1220 1 235 9.9E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CP478_RS12820 ba4e7705ba37827297aec88070f2191e 512 Gene3D G3DSA:3.40.720.10 318 432 8.2E-7 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS12820 ba4e7705ba37827297aec88070f2191e 512 Gene3D G3DSA:3.40.720.10 140 294 0.014 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS12820 ba4e7705ba37827297aec88070f2191e 512 Pfam PF04185 Phosphoesterase family 43 426 5.0E-129 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CP478_RS04550 ca264ce5fc9f7937e1f731af00bab73f 214 Pfam PF14032 PknH-like extracellular domain 36 212 2.2E-26 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS02545 dfeb826491149c88e1bcd1e99eac64e2 148 Pfam PF10783 Protein of unknown function (DUF2599) 46 142 5.7E-40 T 28-03-2018 IPR019719 Protein of unknown function DUF2599 CP478_RS17780 64abd89e10ddccdb001c29c7870cf046 213 SUPERFAMILY SSF53271 43 212 4.01E-14 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CP478_RS17780 64abd89e10ddccdb001c29c7870cf046 213 Gene3D G3DSA:3.40.50.2020 56 213 8.4E-18 T 28-03-2018 CP478_RS15110 6f57fa4c04b7d773c1ff9bcffa79093e 88 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 16 56 2.1E-9 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 385 90.912 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 Gene3D G3DSA:3.40.50.300 2 368 1.8E-24 T 28-03-2018 CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 379 8.1E-135 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 ProSitePatterns PS00618 RecF protein signature 2. 321 339 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 353 1.4E-15 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 SUPERFAMILY SSF52540 3 222 2.4E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS00015 eb31a3b0f94e9952b896cfc6673a3546 385 SUPERFAMILY SSF52540 254 342 2.4E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 PRINTS PR01228 Eggshell protein signature 404 422 5.3E-6 T 28-03-2018 CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 PRINTS PR01228 Eggshell protein signature 336 351 5.3E-6 T 28-03-2018 CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 PRINTS PR01228 Eggshell protein signature 365 375 5.3E-6 T 28-03-2018 CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 PRINTS PR01228 Eggshell protein signature 252 263 5.3E-6 T 28-03-2018 CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 SUPERFAMILY SSF140459 8 84 8.11E-21 T 28-03-2018 CP478_RS09035 cb1b5c9977909522cb6fc97d5b555596 1011 Pfam PF00934 PE family 1 93 3.5E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09570 354da46af343b77091f288a681a162a0 273 Gene3D G3DSA:3.40.720.10 68 194 2.8E-8 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CP478_RS09570 354da46af343b77091f288a681a162a0 273 Pfam PF04185 Phosphoesterase family 15 188 1.1E-53 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CP478_RS10460 24e721179b89b40cf8c5e9e1dac3c26a 371 Pfam PF00144 Beta-lactamase 58 363 1.2E-61 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS10460 24e721179b89b40cf8c5e9e1dac3c26a 371 SUPERFAMILY SSF56601 52 362 1.09E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS10460 24e721179b89b40cf8c5e9e1dac3c26a 371 Gene3D G3DSA:3.40.710.10 26 370 4.9E-73 T 28-03-2018 CP478_RS03310 2d7f90693e1410e0ff6ebbd3a8db48c9 75 Gene3D G3DSA:1.10.1220.10 1 45 1.5E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS03310 2d7f90693e1410e0ff6ebbd3a8db48c9 75 SUPERFAMILY SSF47598 1 39 9.64E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS18390 062d030f1f101e4845b27085da3a6253 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 54 1.7E-18 T 28-03-2018 CP478_RS18390 062d030f1f101e4845b27085da3a6253 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 71 5.5E-20 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS18390 062d030f1f101e4845b27085da3a6253 91 Gene3D G3DSA:3.40.1620.10 1 50 2.0E-14 T 28-03-2018 CP478_RS18390 062d030f1f101e4845b27085da3a6253 91 SUPERFAMILY SSF143120 3 73 1.05E-20 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CP478_RS07135 260327103c941105161e92e916d26f01 404 Pfam PF00953 Glycosyl transferase family 4 110 274 5.3E-34 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 SUPERFAMILY SSF140459 3 170 2.62E-56 T 28-03-2018 CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF00823 PPE family 5 161 2.5E-56 T 28-03-2018 IPR000030 PPE family CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Gene3D G3DSA:1.10.287.1060 25 111 9.1E-6 T 28-03-2018 CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 279 317 3.1E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 209 248 4.7E-11 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 426 464 5.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 397 435 3.2E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 467 502 4.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 315 352 9.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 358 394 1.4E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 249 288 6.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS06210 d9ed268098be02bdfa0cbe6c3a518e15 618 Pfam PF01469 Pentapeptide repeats (8 copies) 289 327 2.5E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04655 62c37ee3f4fde696f849eaea4634550e 212 Gene3D G3DSA:3.30.70.100 118 198 0.024 T 28-03-2018 CP478_RS16680 fd7bcd2d77d52800d215d48ccaf820e8 524 Pfam PF00743 Flavin-binding monooxygenase-like 24 229 2.2E-15 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CP478_RS16680 fd7bcd2d77d52800d215d48ccaf820e8 524 SUPERFAMILY SSF51905 310 429 4.12E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16680 fd7bcd2d77d52800d215d48ccaf820e8 524 SUPERFAMILY SSF51905 24 240 4.12E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16680 fd7bcd2d77d52800d215d48ccaf820e8 524 Gene3D G3DSA:3.50.50.60 178 510 1.6E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS16680 fd7bcd2d77d52800d215d48ccaf820e8 524 Gene3D G3DSA:3.50.50.60 22 177 1.4E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10400 68341d1d730d13b4d6794d3b7e241e41 201 SUPERFAMILY SSF49777 56 200 5.23E-37 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS10400 68341d1d730d13b4d6794d3b7e241e41 201 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 74 193 1.4E-18 T 28-03-2018 IPR005247 YbhB/YbcL CP478_RS10400 68341d1d730d13b4d6794d3b7e241e41 201 Gene3D G3DSA:3.90.280.10 39 201 4.1E-41 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS10400 68341d1d730d13b4d6794d3b7e241e41 201 Pfam PF01161 Phosphatidylethanolamine-binding protein 69 199 3.4E-28 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CP478_RS07495 8e74663fd0a703e7b99ace21cf5ea4cb 273 Gene3D G3DSA:3.30.460.10 43 166 4.2E-13 T 28-03-2018 CP478_RS07495 8e74663fd0a703e7b99ace21cf5ea4cb 273 Pfam PF04607 Region found in RelA / SpoT proteins 76 174 8.4E-10 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CP478_RS07495 8e74663fd0a703e7b99ace21cf5ea4cb 273 SMART SM00954 76 186 3.5E-14 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CP478_RS07495 8e74663fd0a703e7b99ace21cf5ea4cb 273 SUPERFAMILY SSF81301 44 194 2.78E-19 T 28-03-2018 CP478_RS02790 78c862755c156a77e6a81287d5aff9f7 101 SUPERFAMILY SSF53335 2 76 4.65E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02790 78c862755c156a77e6a81287d5aff9f7 101 Gene3D G3DSA:1.10.287.840 1 69 3.5E-17 T 28-03-2018 IPR023143 Mycolic acid cyclopropane synthase-like domain CP478_RS03765 c2f2099688c451b164a21ae62f792044 470 Pfam PF00535 Glycosyl transferase family 2 85 240 1.4E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS03765 c2f2099688c451b164a21ae62f792044 470 TIGRFAM TIGR03965 mycofact_glyco: mycofactocin system glycosyltransferase 12 469 2.2E-180 T 28-03-2018 IPR023981 Putative mycofactocin biosynthesis glycosyltransferase CP478_RS03765 c2f2099688c451b164a21ae62f792044 470 Gene3D G3DSA:3.90.550.10 61 299 6.6E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS03765 c2f2099688c451b164a21ae62f792044 470 SUPERFAMILY SSF53448 79 331 4.64E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 SUPERFAMILY SSF53187 358 447 7.6E-56 T 28-03-2018 CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 SUPERFAMILY SSF53187 8 194 7.6E-56 T 28-03-2018 CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 Gene3D G3DSA:3.30.70.360 213 349 1.2E-22 T 28-03-2018 CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 Pfam PF01546 Peptidase family M20/M25/M40 85 446 2.4E-36 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 Pfam PF07687 Peptidase dimerisation domain 206 333 1.5E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 SUPERFAMILY SSF55031 297 333 5.86E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 SUPERFAMILY SSF55031 209 251 5.86E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 Gene3D G3DSA:3.40.630.10 5 212 1.8E-42 T 28-03-2018 CP478_RS11645 f8a0e7d95791f5dae9712b24b9e38f34 448 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 84 93 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CP478_RS20785 5cbbeac4d526ed9497a9c19db9429dbf 302 Pfam PF01040 UbiA prenyltransferase family 48 266 2.5E-19 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 PRINTS PR01228 Eggshell protein signature 175 190 5.3E-6 T 28-03-2018 CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 PRINTS PR01228 Eggshell protein signature 235 253 5.3E-6 T 28-03-2018 CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 PRINTS PR01228 Eggshell protein signature 76 92 5.3E-6 T 28-03-2018 CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 PRINTS PR01228 Eggshell protein signature 206 216 5.3E-6 T 28-03-2018 CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 Pfam PF00934 PE family 4 95 8.5E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09820 e672e0f5ed6c8914d4b8b468b69d254a 639 SUPERFAMILY SSF140459 10 86 4.18E-23 T 28-03-2018 CP478_RS06275 25703e2824ab2d1526248e4d2fa2fc76 303 SUPERFAMILY SSF82866 121 281 5.89E-19 T 28-03-2018 CP478_RS06275 25703e2824ab2d1526248e4d2fa2fc76 303 Gene3D G3DSA:1.20.1640.10 131 285 1.3E-19 T 28-03-2018 CP478_RS06275 25703e2824ab2d1526248e4d2fa2fc76 303 Pfam PF03176 MMPL family 44 276 5.8E-39 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CP478_RS20095 ac60fed7aaf12686425fd21a34482709 386 SUPERFAMILY SSF52540 226 287 1.7E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20095 ac60fed7aaf12686425fd21a34482709 386 SUPERFAMILY SSF52540 18 181 1.7E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS20095 ac60fed7aaf12686425fd21a34482709 386 Pfam PF02374 Anion-transporting ATPase 20 285 5.5E-27 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CP478_RS20095 ac60fed7aaf12686425fd21a34482709 386 Gene3D G3DSA:3.40.50.300 4 384 1.3E-86 T 28-03-2018 CP478_RS08190 374a484242ab32033eeb792744a445cb 100 Gene3D G3DSA:1.10.1220.10 17 100 1.0E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS07680 192d7023343b4f611c7345ed9cf1b0ea 655 Hamap MF_00983 Probable primosomal protein N' [priA]. 1 654 21.443 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CP478_RS15655 a02f65293dc11e6794021201ad930748 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 126 13.474 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS15655 a02f65293dc11e6794021201ad930748 126 Pfam PF01850 PIN domain 2 120 1.0E-18 T 28-03-2018 IPR002716 PIN domain CP478_RS15655 a02f65293dc11e6794021201ad930748 126 SUPERFAMILY SSF88723 1 121 1.26E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15655 a02f65293dc11e6794021201ad930748 126 Gene3D G3DSA:3.40.50.1010 1 126 1.2E-16 T 28-03-2018 IPR029060 PIN domain-like CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 Pfam PF02803 Thiolase, C-terminal domain 281 403 2.6E-48 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 SUPERFAMILY SSF53901 282 403 9.79E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 Pfam PF00108 Thiolase, N-terminal domain 5 272 1.2E-62 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 SUPERFAMILY SSF53901 3 281 1.05E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 Gene3D G3DSA:3.40.47.10 1 276 4.6E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 402 7.7E-138 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 PIRSF PIRSF000429 1 405 1.8E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CP478_RS05890 4ffaf0fac401275aa928ad20e47ca0d2 405 Gene3D G3DSA:3.40.47.10 277 401 1.4E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS01410 9f87322f788b719ffee60ccd33785704 469 Gene3D G3DSA:1.20.1250.20 221 456 1.6E-16 T 28-03-2018 CP478_RS01410 9f87322f788b719ffee60ccd33785704 469 Pfam PF07690 Major Facilitator Superfamily 40 407 6.5E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS01410 9f87322f788b719ffee60ccd33785704 469 Gene3D G3DSA:1.20.1250.20 23 212 4.2E-14 T 28-03-2018 CP478_RS01410 9f87322f788b719ffee60ccd33785704 469 SUPERFAMILY SSF103473 27 448 6.28E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS03045 2cdb2741a47021f8df9d2c73ce7567f5 88 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 4.0E-27 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 CP478_RS03045 2cdb2741a47021f8df9d2c73ce7567f5 88 SUPERFAMILY SSF50118 1 78 7.19E-30 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS13530 91684d08e866eb186ef39c0eef0d0e04 138 Gene3D G3DSA:3.10.129.10 3 138 1.1E-24 T 28-03-2018 CP478_RS13530 91684d08e866eb186ef39c0eef0d0e04 138 SUPERFAMILY SSF54637 5 136 2.11E-23 T 28-03-2018 IPR029069 HotDog domain CP478_RS13530 91684d08e866eb186ef39c0eef0d0e04 138 Pfam PF13279 Thioesterase-like superfamily 11 119 1.5E-9 T 28-03-2018 CP478_RS01110 01e8a3a62a733b79050b62bf293e789b 427 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 63 370 3.9E-12 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CP478_RS01110 01e8a3a62a733b79050b62bf293e789b 427 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 62 361 9.0E-37 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CP478_RS16620 624a656c63caebf2df35c955e45e30f2 327 Pfam PF08241 Methyltransferase domain 82 179 7.2E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS16620 624a656c63caebf2df35c955e45e30f2 327 Gene3D G3DSA:3.40.50.150 25 283 3.6E-32 T 28-03-2018 CP478_RS16620 624a656c63caebf2df35c955e45e30f2 327 SUPERFAMILY SSF53335 237 326 2.86E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS16620 624a656c63caebf2df35c955e45e30f2 327 SUPERFAMILY SSF53335 42 191 2.86E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02890 8eb5a22f3f3d6152cc0a206eedae86e6 210 SUPERFAMILY SSF53448 1 192 1.53E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS02890 8eb5a22f3f3d6152cc0a206eedae86e6 210 Pfam PF00535 Glycosyl transferase family 2 1 125 2.0E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS02890 8eb5a22f3f3d6152cc0a206eedae86e6 210 Gene3D G3DSA:3.90.550.10 1 207 1.4E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS01655 ff43c4d3862d7a25eb3d7e16004906c0 218 Gene3D G3DSA:2.40.440.10 39 217 6.4E-5 T 28-03-2018 CP478_RS04405 e5b600025260eee28b1b88972f0e6c18 289 Gene3D G3DSA:3.30.470.10 2 112 4.9E-27 T 28-03-2018 CP478_RS04405 e5b600025260eee28b1b88972f0e6c18 289 Pfam PF01063 Amino-transferase class IV 29 261 5.5E-40 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CP478_RS04405 e5b600025260eee28b1b88972f0e6c18 289 SUPERFAMILY SSF56752 3 283 3.14E-55 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CP478_RS04405 e5b600025260eee28b1b88972f0e6c18 289 Gene3D G3DSA:3.20.10.10 115 276 3.1E-31 T 28-03-2018 CP478_RS07985 4a05c924a2b98301793883d77774d659 310 Pfam PF02628 Cytochrome oxidase assembly protein 17 291 4.3E-9 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CP478_RS12135 5ee4e328a8c950d5da05f1c238588509 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 141 9.442 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 Gene3D G3DSA:2.130.10.10 90 228 9.3E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 Gene3D G3DSA:2.130.10.10 229 359 3.5E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 Gene3D G3DSA:2.130.10.10 4 89 3.5E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 SUPERFAMILY SSF51004 233 382 4.45E-36 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 SUPERFAMILY SSF51004 95 206 4.45E-36 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CP478_RS05805 7dbe24ea0c18ebf33d87e6eeb505eecc 393 SUPERFAMILY SSF51004 12 98 3.4E-9 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CP478_RS13950 aea01dc94a43014eb9ba4841849a53e8 92 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 57 89 1.0E-5 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS12080 de866424c7e31796fe10263bd38b0047 520 SUPERFAMILY SSF53474 91 154 1.13E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12080 de866424c7e31796fe10263bd38b0047 520 SUPERFAMILY SSF53474 200 482 1.13E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12080 de866424c7e31796fe10263bd38b0047 520 Pfam PF00561 alpha/beta hydrolase fold 105 403 6.7E-65 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS12080 de866424c7e31796fe10263bd38b0047 520 Pfam PF08386 TAP-like protein 421 518 5.6E-21 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CP478_RS12080 de866424c7e31796fe10263bd38b0047 520 Gene3D G3DSA:3.40.50.1820 85 512 9.2E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14310 56a183cf4e893e8500ade79b05650616 217 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 93 3.3E-10 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS14310 56a183cf4e893e8500ade79b05650616 217 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 71 93 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CP478_RS13240 524b2742d441fde2f1a5d75d78479aba 480 SUPERFAMILY SSF53300 309 439 3.17E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS13240 524b2742d441fde2f1a5d75d78479aba 480 Pfam PF05762 VWA domain containing CoxE-like protein 253 473 1.4E-64 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CP478_RS13240 524b2742d441fde2f1a5d75d78479aba 480 PIRSF PIRSF010256 5 480 2.5E-141 T 28-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 CP478_RS13240 524b2742d441fde2f1a5d75d78479aba 480 Gene3D G3DSA:3.40.50.410 278 457 3.9E-5 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS03505 aadbe2fdad0e52011fbe30e748482406 224 SUPERFAMILY SSF109998 23 154 1.92E-5 T 28-03-2018 IPR027304 Trigger factor/SurA domain CP478_RS03505 aadbe2fdad0e52011fbe30e748482406 224 Gene3D G3DSA:1.10.4030.10 18 181 8.8E-7 T 28-03-2018 CP478_RS16780 a193148ee96c5cdb3e7734df16d55008 136 Pfam PF05305 Protein of unknown function (DUF732) 39 129 7.9E-16 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS06975 1aaec92160cc1a63b9bffd9b22b2a27c 180 Gene3D G3DSA:3.40.190.10 1 159 0.0011 T 28-03-2018 CP478_RS06975 1aaec92160cc1a63b9bffd9b22b2a27c 180 Pfam PF12079 Protein of unknown function (DUF3558) 16 177 7.1E-30 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CP478_RS16920 58d8f327faabcf921a6c35566e588c5a 306 Pfam PF05661 Protein of unknown function (DUF808) 4 291 1.4E-113 T 28-03-2018 IPR008526 Inner membrane protein YedI CP478_RS16920 58d8f327faabcf921a6c35566e588c5a 306 PIRSF PIRSF016660 1 303 1.9E-101 T 28-03-2018 IPR008526 Inner membrane protein YedI CP478_RS10185 420e6062179de2e03e12318c3e318506 228 Gene3D G3DSA:3.30.70.100 101 216 4.2E-16 T 28-03-2018 CP478_RS10185 420e6062179de2e03e12318c3e318506 228 SUPERFAMILY SSF54909 113 173 1.42E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CP478_RS10185 420e6062179de2e03e12318c3e318506 228 Pfam PF07110 EthD domain 121 193 5.5E-5 T 28-03-2018 IPR009799 EthD domain CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF00823 PPE family 5 162 2.9E-55 T 28-03-2018 IPR000030 PPE family CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 263 302 2.7E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 928 965 2.4E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2708 2745 2.5E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2625 2663 2.3E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 845 883 9.5E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2581 2616 1.0E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 1475 1513 3.2E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 1432 1470 6.6E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 1515 1552 3.3E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 346 383 1.3E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2668 2706 2.6E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3334 3373 1.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3255 3293 2.8E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 385 424 8.0E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2747 2786 1.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3295 3332 2.6E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 888 925 1.5E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3146 3183 1.5E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 967 1005 3.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 1365 1398 2.1E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3212 3250 2.2E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2031 2069 1.3E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2115 2152 2.1E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2558 2591 1.3E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2154 2192 2.0E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 778 816 3.6E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 306 344 5.1E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 3166 3203 1.1E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 1386 1423 2.7E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Pfam PF01469 Pentapeptide repeats (8 copies) 2074 2112 8.4E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 SUPERFAMILY SSF140459 3 173 1.36E-56 T 28-03-2018 CP478_RS18350 8b9ad35af42160f8a79e82a25659fc9a 3716 Gene3D G3DSA:1.10.287.1060 22 107 3.0E-5 T 28-03-2018 CP478_RS04410 a497e7e1146ddda675efee131a4765ad 226 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 57 225 29.484 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 CP478_RS04410 a497e7e1146ddda675efee131a4765ad 226 Pfam PF08768 Domain of unknown function (DUF1794) 69 223 1.3E-40 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 CP478_RS04410 a497e7e1146ddda675efee131a4765ad 226 SUPERFAMILY SSF50814 60 223 2.21E-32 T 28-03-2018 IPR012674 Calycin CP478_RS04410 a497e7e1146ddda675efee131a4765ad 226 Gene3D G3DSA:2.40.128.20 27 226 1.2E-53 T 28-03-2018 IPR012674 Calycin CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 SUPERFAMILY SSF53474 161 354 2.18E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 SUPERFAMILY SSF140459 46 122 4.45E-23 T 28-03-2018 CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 Gene3D G3DSA:3.40.50.1820 158 365 2.1E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 Pfam PF08237 PE-PPE domain 196 415 1.4E-69 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 Pfam PF00934 PE family 40 130 4.8E-30 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS00820 dbba20e885542434eb87d4c6f77ceef8 588 Gene3D G3DSA:1.10.287.1060 39 138 4.2E-4 T 28-03-2018 CP478_RS17735 86b50e22fa5014db3a06e2a64e69da2a 200 Pfam PF06974 Protein of unknown function (DUF1298) 53 195 1.3E-19 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS08155 b6c0c0b6ac1f29163752402ecf51ebca 118 Pfam PF13564 DoxX-like family 11 106 6.6E-11 T 28-03-2018 IPR032808 DoxX family CP478_RS20475 a4fc5c1d788819afb26ea447f66e65d5 130 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 55 99 1.1E-17 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CP478_RS20475 a4fc5c1d788819afb26ea447f66e65d5 130 Gene3D G3DSA:1.10.10.10 23 66 4.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS20475 a4fc5c1d788819afb26ea447f66e65d5 130 SUPERFAMILY SSF46955 55 103 2.2E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS20475 a4fc5c1d788819afb26ea447f66e65d5 130 Pfam PF12728 Helix-turn-helix domain 55 102 4.4E-13 T 28-03-2018 CP478_RS20475 a4fc5c1d788819afb26ea447f66e65d5 130 Gene3D G3DSA:1.10.10.10 67 111 9.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS18820 f079872d658681d34bd5dfc0eb64a2f1 280 Gene3D G3DSA:3.40.50.1820 27 209 3.8E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18820 f079872d658681d34bd5dfc0eb64a2f1 280 SUPERFAMILY SSF53474 14 208 2.63E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS16815 c4eac1d20a58dbc1bf378e4dcd4b6e61 118 Pfam PF04343 Protein of unknown function, DUF488 9 115 2.3E-25 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.1E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16875 29e80419d184722999853d1f178d8c72 276 Gene3D G3DSA:3.40.50.720 1 187 1.1E-51 T 28-03-2018 CP478_RS16875 29e80419d184722999853d1f178d8c72 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0069 T 28-03-2018 CP478_RS16875 29e80419d184722999853d1f178d8c72 276 SUPERFAMILY SSF51735 1 265 1.71E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS16875 29e80419d184722999853d1f178d8c72 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS16875 29e80419d184722999853d1f178d8c72 276 Gene3D G3DSA:3.40.50.720 188 245 0.068 T 28-03-2018 CP478_RS16875 29e80419d184722999853d1f178d8c72 276 Pfam PF00106 short chain dehydrogenase 7 198 1.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS00155 57fd3a66830d2f40dae12ce80745d8f5 105 Gene3D G3DSA:1.10.287.1060 2 100 1.8E-9 T 28-03-2018 CP478_RS00155 57fd3a66830d2f40dae12ce80745d8f5 105 ProDom PD069881 MB0028 RV0027/MT0030 1 105 3.0E-47 T 28-03-2018 CP478_RS00155 57fd3a66830d2f40dae12ce80745d8f5 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 6.4E-29 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 124 137 - T 28-03-2018 IPR033135 ClpP, histidine active site CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 Pfam PF00574 Clp protease 30 206 3.9E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 PRINTS PR00127 Clp protease catalytic subunit P signature 71 91 6.0E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 6.0E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 PRINTS PR00127 Clp protease catalytic subunit P signature 123 142 6.0E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 PRINTS PR00127 Clp protease catalytic subunit P signature 31 46 6.0E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 PRINTS PR00127 Clp protease catalytic subunit P signature 102 119 6.0E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 Gene3D G3DSA:3.90.226.10 14 208 2.6E-37 T 28-03-2018 CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 SUPERFAMILY SSF52096 24 208 5.36E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 102 113 - T 28-03-2018 IPR018215 ClpP, Ser active site CP478_RS13440 c25d2d617436bc7f330e28c498126234 214 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 15 207 38.462 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CP478_RS12545 c082049b8cc09fd33467ed14257bba25 114 Pfam PF12587 Protein of unknown function (DUF3761) 57 113 9.9E-23 T 28-03-2018 IPR022236 Protein of unknown function DUF3761 CP478_RS02695 6b13b1578abe2ccfafd983d61375815d 302 PIRSF PIRSF003085 5 302 2.2E-97 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CP478_RS02695 6b13b1578abe2ccfafd983d61375815d 302 Gene3D G3DSA:3.40.50.150 12 302 1.4E-52 T 28-03-2018 CP478_RS02695 6b13b1578abe2ccfafd983d61375815d 302 SUPERFAMILY SSF53335 21 302 1.14E-71 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS02695 6b13b1578abe2ccfafd983d61375815d 302 Pfam PF02353 Mycolic acid cyclopropane synthetase 13 298 2.2E-120 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS20540 b32d700e033c6a13085a3691ad83e659 351 Pfam PF01636 Phosphotransferase enzyme family 34 268 4.9E-41 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CP478_RS20540 b32d700e033c6a13085a3691ad83e659 351 SUPERFAMILY SSF56112 10 318 3.94E-45 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS20540 b32d700e033c6a13085a3691ad83e659 351 Gene3D G3DSA:3.90.1200.10 122 303 1.7E-20 T 28-03-2018 CP478_RS20540 b32d700e033c6a13085a3691ad83e659 351 Gene3D G3DSA:3.30.200.20 9 110 5.6E-23 T 28-03-2018 CP478_RS11595 95883e5346c1d56da0dbec0f977ae656 76 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 39 1.2E-4 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS11595 95883e5346c1d56da0dbec0f977ae656 76 Gene3D G3DSA:1.10.1220.10 1 51 1.3E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS19870 912371963964367806f6899119b4e5da 211 Pfam PF02661 Fic/DOC family 64 162 4.5E-15 T 28-03-2018 IPR003812 Fido domain CP478_RS19870 912371963964367806f6899119b4e5da 211 Gene3D G3DSA:1.10.3290.10 22 206 5.5E-21 T 28-03-2018 IPR003812 Fido domain CP478_RS19870 912371963964367806f6899119b4e5da 211 SUPERFAMILY SSF140931 61 204 2.75E-27 T 28-03-2018 IPR003812 Fido domain CP478_RS06245 75066c0529847373b409d7442ea7d131 282 Pfam PF02517 CAAX protease self-immunity 186 269 4.1E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CP478_RS01230 dda7210dca623fcebede2c617e87f858 407 Pfam PF01757 Acyltransferase family 38 370 1.7E-26 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CP478_RS01945 de4ce9b2aa4e1c90c2dedcb53290485b 227 Pfam PF09335 SNARE associated Golgi protein 47 174 6.6E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein CP478_RS15475 f256955f3d0112caadea44ced5fe9fa5 130 SUPERFAMILY SSF88723 1 120 1.35E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15475 f256955f3d0112caadea44ced5fe9fa5 130 Gene3D G3DSA:3.40.50.1010 1 129 1.5E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS15475 f256955f3d0112caadea44ced5fe9fa5 130 Pfam PF01850 PIN domain 4 119 2.4E-16 T 28-03-2018 IPR002716 PIN domain CP478_RS15475 f256955f3d0112caadea44ced5fe9fa5 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 129 13.035 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 SUPERFAMILY SSF53098 2 157 2.12E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 Gene3D G3DSA:3.30.420.10 1 160 9.9E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 3.4E-62 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 1.2E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 2.1E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 2.1E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 2.1E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.1E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 2.1E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS14215 f76dcbee76776ad12d3e97ccfa04ff15 188 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 43.651 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CP478_RS12925 72cc6bf887f73156e89f66f9206e2228 437 Pfam PF13556 PucR C-terminal helix-turn-helix domain 342 388 1.2E-10 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS12925 72cc6bf887f73156e89f66f9206e2228 437 Gene3D G3DSA:1.10.10.60 323 378 2.8E-4 T 28-03-2018 CP478_RS10710 b4f1d23dc4b8417abb2537fda5e40284 342 Pfam PF02470 MlaD protein 37 114 1.1E-16 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS10710 b4f1d23dc4b8417abb2537fda5e40284 342 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 296 2.8E-86 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 SUPERFAMILY SSF53474 5 187 1.9E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 SUPERFAMILY SSF53474 246 353 1.9E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00412 Epoxide hydrolase signature 54 69 9.6E-26 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00412 Epoxide hydrolase signature 328 350 9.6E-26 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00412 Epoxide hydrolase signature 34 52 9.6E-26 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00412 Epoxide hydrolase signature 100 113 9.6E-26 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 4.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 4.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 Pfam PF00561 alpha/beta hydrolase fold 28 129 6.2E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS10545 1d17040b200b607d2392dc4c9508c2dd 356 Gene3D G3DSA:3.40.50.1820 1 356 5.1E-78 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10855 1df50f6246464c76d6657fc5d8b0a607 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 111 3.9E-22 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS10855 1df50f6246464c76d6657fc5d8b0a607 114 Gene3D G3DSA:2.30.30.110 1 114 3.6E-25 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS10855 1df50f6246464c76d6657fc5d8b0a607 114 SUPERFAMILY SSF50118 2 114 3.49E-28 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CP478_RS10855 1df50f6246464c76d6657fc5d8b0a607 114 PIRSF PIRSF033490 1 114 1.8E-34 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 SUPERFAMILY SSF51735 1 242 3.49E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 Pfam PF00106 short chain dehydrogenase 6 203 1.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS17680 6898439ea15e8083da3c5f70a5e47642 282 Gene3D G3DSA:3.40.50.720 1 274 1.6E-48 T 28-03-2018 CP478_RS18380 6473df1bf5ed6de2483af4a2bdedfad6 97 Pfam PF11222 Protein of unknown function (DUF3017) 17 90 6.2E-22 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 CP478_RS05990 c658a8ca2428c9949c47acf9b2000c3a 151 Gene3D G3DSA:2.60.120.180 1 151 7.3E-43 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CP478_RS05990 c658a8ca2428c9949c47acf9b2000c3a 151 SUPERFAMILY SSF49899 2 151 9.27E-47 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CP478_RS05990 c658a8ca2428c9949c47acf9b2000c3a 151 Pfam PF01670 Glycosyl hydrolase family 12 2 151 1.4E-37 T 28-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CP478_RS19405 4849462bd261b0dd904d69882ff44e25 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 209 1.1E-36 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS19405 4849462bd261b0dd904d69882ff44e25 247 SUPERFAMILY SSF52096 6 246 6.59E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS19405 4849462bd261b0dd904d69882ff44e25 247 Gene3D G3DSA:3.90.226.10 3 247 7.5E-50 T 28-03-2018 CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 Pfam PF00571 CBS domain 4 55 2.1E-11 T 28-03-2018 IPR000644 CBS domain CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 Pfam PF00571 CBS domain 71 124 1.3E-11 T 28-03-2018 IPR000644 CBS domain CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 SMART SM00116 11 59 3.8E-5 T 28-03-2018 IPR000644 CBS domain CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 SMART SM00116 77 124 3.1E-11 T 28-03-2018 IPR000644 CBS domain CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 SUPERFAMILY SSF54631 1 125 1.2E-31 T 28-03-2018 CP478_RS14385 9f7541ac70f03e2ccedc059a5d8eb021 143 Gene3D G3DSA:3.10.580.10 1 134 9.1E-30 T 28-03-2018 CP478_RS07255 5ff5071248ea28e67103e6eddfc1edda 152 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 21 149 1.9E-37 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CP478_RS07255 5ff5071248ea28e67103e6eddfc1edda 152 SUPERFAMILY SSF54593 18 150 2.06E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS07255 5ff5071248ea28e67103e6eddfc1edda 152 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 134 1.2E-20 T 28-03-2018 CP478_RS07255 5ff5071248ea28e67103e6eddfc1edda 152 Gene3D G3DSA:3.10.180.10 13 152 3.7E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 SUPERFAMILY SSF56801 8 516 9.68E-79 T 28-03-2018 CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 28-03-2018 IPR020845 AMP-binding, conserved site CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 Pfam PF00501 AMP-binding enzyme 28 420 7.9E-49 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 Gene3D G3DSA:3.40.50.980 162 324 3.5E-24 T 28-03-2018 CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 Gene3D G3DSA:3.40.50.980 2 161 9.0E-13 T 28-03-2018 CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 Gene3D G3DSA:2.30.38.10 329 412 4.0E-12 T 28-03-2018 CP478_RS07370 fe8660c6a9908f8589fe8fc887ef321b 521 Gene3D G3DSA:3.30.300.30 413 518 8.5E-18 T 28-03-2018 CP478_RS05235 230830ec65afc7dd0da121aac1bfcb90 672 SMART SM00327 481 667 1.0E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS05235 230830ec65afc7dd0da121aac1bfcb90 672 Gene3D G3DSA:3.40.50.410 475 646 1.9E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS05235 230830ec65afc7dd0da121aac1bfcb90 672 SUPERFAMILY SSF53300 482 657 1.38E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CP478_RS12540 660b46eacd809d7a3646eb720597195b 281 SUPERFAMILY SSF53474 13 275 7.57E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS12540 660b46eacd809d7a3646eb720597195b 281 Pfam PF12146 Serine aminopeptidase, S33 80 185 8.0E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CP478_RS12540 660b46eacd809d7a3646eb720597195b 281 Gene3D G3DSA:3.40.50.1820 46 276 1.0E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS03120 0990e9c43ea3921284241c88483ac2ea 135 SUPERFAMILY SSF88723 1 123 1.4E-19 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03120 0990e9c43ea3921284241c88483ac2ea 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 14.961 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS03120 0990e9c43ea3921284241c88483ac2ea 135 Pfam PF01850 PIN domain 1 119 5.7E-11 T 28-03-2018 IPR002716 PIN domain CP478_RS03120 0990e9c43ea3921284241c88483ac2ea 135 Gene3D G3DSA:3.40.50.1010 1 126 9.3E-18 T 28-03-2018 IPR029060 PIN domain-like CP478_RS00750 f4664a1c3fd5567526ec324261e86bf5 167 Pfam PF12680 SnoaL-like domain 24 125 7.2E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS00750 f4664a1c3fd5567526ec324261e86bf5 167 Gene3D G3DSA:3.10.450.50 2 163 6.3E-19 T 28-03-2018 CP478_RS00750 f4664a1c3fd5567526ec324261e86bf5 167 SUPERFAMILY SSF54427 6 137 1.91E-22 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS11600 380798814e0af4e8fc9991288834b561 262 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 2 262 2.1E-111 T 28-03-2018 IPR022292 Conserved hypothetical protein CHP03843 CP478_RS14655 f455ad33c346b1cb06a942f435fd8e4f 433 Pfam PF09594 Glycosyltransferase family 87 94 328 9.6E-40 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CP478_RS01620 b001df8db4b7df91e820922630df60eb 141 Gene3D G3DSA:3.40.50.1010 2 141 1.1E-23 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01620 b001df8db4b7df91e820922630df60eb 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 130 13.124 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS01620 b001df8db4b7df91e820922630df60eb 141 Pfam PF01850 PIN domain 7 125 1.4E-10 T 28-03-2018 IPR002716 PIN domain CP478_RS01620 b001df8db4b7df91e820922630df60eb 141 SUPERFAMILY SSF88723 6 123 2.71E-11 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01615 2e45c8a309591f8a71fd55920042ea5f 73 SUPERFAMILY SSF47598 3 53 2.8E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS01615 2e45c8a309591f8a71fd55920042ea5f 73 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 37 2.9E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS01615 2e45c8a309591f8a71fd55920042ea5f 73 Gene3D G3DSA:1.10.1220.10 7 38 2.4E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS21325 3c12f5452f9cec5523476f627c9334fe 846 Pfam PF14021 Tuberculosis necrotizing toxin 751 846 2.7E-15 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CP478_RS21325 3c12f5452f9cec5523476f627c9334fe 846 Gene3D G3DSA:1.10.287.850 252 340 0.35 T 28-03-2018 CP478_RS21325 3c12f5452f9cec5523476f627c9334fe 846 Gene3D G3DSA:1.10.287.1060 1 98 8.7E-10 T 28-03-2018 CP478_RS21325 3c12f5452f9cec5523476f627c9334fe 846 Gene3D G3DSA:1.10.287.1060 145 235 0.021 T 28-03-2018 CP478_RS05910 5ba93c36be769a38f378682d98579b88 240 Pfam PF06271 RDD family 89 233 9.6E-22 T 28-03-2018 IPR010432 RDD CP478_RS01465 b0c4376eb2e232abb1bdbe6bc133e05a 377 SUPERFAMILY SSF53474 25 160 3.05E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01465 b0c4376eb2e232abb1bdbe6bc133e05a 377 SUPERFAMILY SSF53474 304 375 3.05E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS01465 b0c4376eb2e232abb1bdbe6bc133e05a 377 Gene3D G3DSA:3.40.50.1820 8 377 8.4E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 Pfam PF00823 PPE family 5 164 7.8E-57 T 28-03-2018 IPR000030 PPE family CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 SUPERFAMILY SSF140459 2 173 1.31E-57 T 28-03-2018 CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 Pfam PF01469 Pentapeptide repeats (8 copies) 290 326 1.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 Pfam PF01469 Pentapeptide repeats (8 copies) 235 274 4.0E-7 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 Pfam PF01469 Pentapeptide repeats (8 copies) 265 301 2.0E-6 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS04790 3b8b57459c3eebda9be69dac601a8bfa 439 Gene3D G3DSA:1.10.287.1060 19 111 2.2E-5 T 28-03-2018 CP478_RS00540 27d71e73fa43881c9de4caca02998504 289 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 263 1.5E-30 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CP478_RS00540 27d71e73fa43881c9de4caca02998504 289 Gene3D G3DSA:3.60.130.10 1 280 3.5E-39 T 28-03-2018 CP478_RS00540 27d71e73fa43881c9de4caca02998504 289 SUPERFAMILY SSF51197 7 280 5.95E-53 T 28-03-2018 CP478_RS03250 970d91bc7bdb6942431dc6e41b3917d9 81 Pfam PF07704 Rv0623-like transcription factor 1 80 2.6E-23 T 28-03-2018 IPR011660 Antitoxin VapB-like CP478_RS01830 2e5f581f004519748151b5e57c3edb67 640 SUPERFAMILY SSF52540 49 289 3.94E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01830 2e5f581f004519748151b5e57c3edb67 640 Pfam PF00350 Dynamin family 73 220 1.7E-9 T 28-03-2018 IPR022812 Dynamin superfamily CP478_RS01830 2e5f581f004519748151b5e57c3edb67 640 Gene3D G3DSA:3.40.50.300 46 614 6.0E-26 T 28-03-2018 CP478_RS00980 a997e990b60f2789c8e842e1fd9dd6c0 369 Pfam PF09992 Phosphodiester glycosidase 150 365 5.9E-8 T 28-03-2018 IPR018711 Phosphodiester glycosidase CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 Gene3D G3DSA:3.40.50.720 11 260 4.9E-79 T 28-03-2018 CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 Gene3D G3DSA:3.40.250.10 271 383 2.5E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 SUPERFAMILY SSF69572 11 356 3.01E-104 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 SMART SM00450 287 384 7.3E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 Pfam PF00899 ThiF family 22 255 1.4E-65 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS17055 5bb1cc5c303017a2b58229463a93f2cc 389 Pfam PF00581 Rhodanese-like domain 291 380 1.5E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CP478_RS21120 b7a647dacbddcf8e6fc937091d09cc68 392 SUPERFAMILY SSF49879 29 117 1.46E-6 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CP478_RS21120 b7a647dacbddcf8e6fc937091d09cc68 392 Gene3D G3DSA:1.10.260.40 331 387 0.012 T 28-03-2018 CP478_RS21120 b7a647dacbddcf8e6fc937091d09cc68 392 Gene3D G3DSA:2.60.200.20 10 144 3.9E-6 T 28-03-2018 CP478_RS21120 b7a647dacbddcf8e6fc937091d09cc68 392 Gene3D G3DSA:1.10.260.40 165 234 8.7E-5 T 28-03-2018 CP478_RS17275 7a265ddc4d119fd2304cbb91d920ee09 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.191 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CP478_RS17275 7a265ddc4d119fd2304cbb91d920ee09 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 3.1E-24 T 28-03-2018 CP478_RS17225 a337a382a4f948c316a29bf4e035bc9e 128 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 128 17.645 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CP478_RS17225 a337a382a4f948c316a29bf4e035bc9e 128 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 127 1.3E-33 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS10045 30733e61d2f4ecd646ec9e742b7fa5f1 140 Pfam PF03061 Thioesterase superfamily 48 127 2.9E-15 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CP478_RS10045 30733e61d2f4ecd646ec9e742b7fa5f1 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 130 1.1E-22 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CP478_RS10045 30733e61d2f4ecd646ec9e742b7fa5f1 140 Gene3D G3DSA:3.10.129.10 9 133 1.0E-25 T 28-03-2018 CP478_RS10045 30733e61d2f4ecd646ec9e742b7fa5f1 140 SUPERFAMILY SSF54637 12 130 1.85E-28 T 28-03-2018 IPR029069 HotDog domain CP478_RS20580 765359c28779efd721c97fb33f41412c 90 Gene3D G3DSA:3.90.20.10 2 90 4.5E-6 T 28-03-2018 CP478_RS03570 0b7b0e7e0cd297cdd1a9f4feeeb2f0a2 122 Gene3D G3DSA:1.10.1220.10 6 84 1.8E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS01270 00111a1ea9dc946e1d8d6900d19819bc 482 Pfam PF06762 Lipase maturation factor 293 472 5.2E-66 T 28-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 CP478_RS01270 00111a1ea9dc946e1d8d6900d19819bc 482 Pfam PF06762 Lipase maturation factor 121 275 5.1E-59 T 28-03-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 CP478_RS09565 d071ba42734f4df64ca7707ca7a6bca8 563 Pfam PF13810 Domain of unknown function (DUF4185) 234 559 4.1E-120 T 28-03-2018 IPR025442 Domain of unknown function DUF4185 CP478_RS11140 dbc85c1a084b358ee520eaa85562bb2b 265 Pfam PF02136 Nuclear transport factor 2 (NTF2) domain 10 128 7.5E-13 T 28-03-2018 IPR002075 Nuclear transport factor 2 GO:0005622|GO:0006810 CP478_RS11140 dbc85c1a084b358ee520eaa85562bb2b 265 SUPERFAMILY SSF54427 3 130 4.7E-19 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS11140 dbc85c1a084b358ee520eaa85562bb2b 265 Gene3D G3DSA:3.10.450.50 1 133 1.3E-16 T 28-03-2018 CP478_RS19995 50b4c8acd17014812945293da096fd36 256 Gene3D G3DSA:1.10.3290.10 17 254 5.9E-11 T 28-03-2018 IPR003812 Fido domain CP478_RS04470 3c67b5a0268a678a2d5e809bdd0424c0 338 Gene3D G3DSA:1.10.620.20 1 320 5.0E-96 T 28-03-2018 CP478_RS04470 3c67b5a0268a678a2d5e809bdd0424c0 338 PIRSF PIRSF000346 1 327 1.9E-113 T 28-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CP478_RS04470 3c67b5a0268a678a2d5e809bdd0424c0 338 SUPERFAMILY SSF47240 1 307 6.76E-87 T 28-03-2018 IPR009078 Ferritin-like superfamily CP478_RS04470 3c67b5a0268a678a2d5e809bdd0424c0 338 Pfam PF03405 Fatty acid desaturase 7 316 1.6E-88 T 28-03-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 CP478_RS06560 11b407fb302e58175311eaf8c64ff109 98 SUPERFAMILY SSF140453 4 97 2.35E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS06560 11b407fb302e58175311eaf8c64ff109 98 Pfam PF06013 Proteins of 100 residues with WXG 5 90 1.6E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS06560 11b407fb302e58175311eaf8c64ff109 98 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 6.8E-20 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS06560 11b407fb302e58175311eaf8c64ff109 98 Gene3D G3DSA:1.10.287.1060 1 98 2.5E-14 T 28-03-2018 CP478_RS02150 cd9b97b3c2c99f6fe1df6b5ea0d17576 142 Pfam PF05423 Mycobacterium membrane protein 6 142 1.6E-66 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS10525 374adbcdb2bccf61dbafaa4575fde4c7 318 Pfam PF00378 Enoyl-CoA hydratase/isomerase 109 262 5.1E-23 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS10525 374adbcdb2bccf61dbafaa4575fde4c7 318 Pfam PF00378 Enoyl-CoA hydratase/isomerase 36 93 1.0E-11 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS10525 374adbcdb2bccf61dbafaa4575fde4c7 318 SUPERFAMILY SSF52096 22 270 3.39E-56 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS10525 374adbcdb2bccf61dbafaa4575fde4c7 318 Gene3D G3DSA:3.90.226.10 19 283 4.2E-55 T 28-03-2018 CP478_RS11605 cfeb028a661af0142117d1391bcbe6d2 195 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 179 7.7E-79 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CP478_RS11605 cfeb028a661af0142117d1391bcbe6d2 195 Pfam PF11290 Protein of unknown function (DUF3090) 6 175 9.8E-68 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CP478_RS01095 c102d94060e3a0698504266462e3dcf5 167 Gene3D G3DSA:1.10.260.40 89 156 2.9E-6 T 28-03-2018 CP478_RS09430 ffe22de3b87c83b00685d6a48170625d 312 SUPERFAMILY SSF53335 15 292 2.08E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS09430 ffe22de3b87c83b00685d6a48170625d 312 Gene3D G3DSA:3.40.50.150 1 288 8.4E-55 T 28-03-2018 CP478_RS09430 ffe22de3b87c83b00685d6a48170625d 312 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 17 278 1.1E-78 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS09430 ffe22de3b87c83b00685d6a48170625d 312 Pfam PF04072 Leucine carboxyl methyltransferase 19 203 3.6E-64 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 Gene3D G3DSA:1.10.1660.10 58 142 3.3E-19 T 28-03-2018 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 Gene3D G3DSA:1.10.1660.10 1 57 6.1E-23 T 28-03-2018 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 Pfam PF00376 MerR family regulatory protein 2 39 7.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 SUPERFAMILY SSF46955 1 113 4.76E-34 T 28-03-2018 IPR009061 Putative DNA-binding domain CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 SMART SM00422 1 70 5.0E-31 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CP478_RS18265 1207d5760cf942c2bd946c8aaefaff7c 146 Pfam PF09278 MerR, DNA binding 44 108 1.5E-18 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CP478_RS20155 b28ffb4a3a1c245c0d4aaec0cdb256d1 217 Pfam PF13559 Domain of unknown function (DUF4129) 121 190 1.9E-11 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CP478_RS21105 41a4e616849fc4b5b81992fa398d1efe 390 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 139 345 5.8E-7 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CP478_RS21105 41a4e616849fc4b5b81992fa398d1efe 390 Gene3D G3DSA:3.40.50.300 131 364 5.7E-22 T 28-03-2018 CP478_RS21105 41a4e616849fc4b5b81992fa398d1efe 390 SUPERFAMILY SSF52540 135 346 1.39E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS02455 4824ebe952c17c6025e17e3d6f8920e0 79 Pfam PF16936 Putative holin 1 77 2.7E-39 T 28-03-2018 IPR031614 Putative holin CP478_RS12005 741688f45af9198129dc8fbf090d352a 512 Gene3D G3DSA:1.20.1250.20 236 420 3.6E-8 T 28-03-2018 CP478_RS12005 741688f45af9198129dc8fbf090d352a 512 Gene3D G3DSA:1.20.1250.20 8 215 8.7E-7 T 28-03-2018 CP478_RS12005 741688f45af9198129dc8fbf090d352a 512 SUPERFAMILY SSF103473 25 410 4.84E-14 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS12635 24fb77c7c4ccb299bea3b2984b9ed551 274 Gene3D G3DSA:1.10.3720.10 2 262 5.9E-41 T 28-03-2018 CP478_RS12635 24fb77c7c4ccb299bea3b2984b9ed551 274 SUPERFAMILY SSF161098 5 274 3.46E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS12635 24fb77c7c4ccb299bea3b2984b9ed551 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 267 5.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS18890 60ace1bc4407a45b7ceb5a7d61de2bae 226 SMART SM01110 45 226 1.3E-94 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS18890 60ace1bc4407a45b7ceb5a7d61de2bae 226 Pfam PF01083 Cutinase 47 225 3.7E-54 T 28-03-2018 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 CP478_RS18890 60ace1bc4407a45b7ceb5a7d61de2bae 226 SUPERFAMILY SSF53474 46 225 4.35E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS18890 60ace1bc4407a45b7ceb5a7d61de2bae 226 Gene3D G3DSA:3.40.50.1820 46 226 1.1E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00490 a93c086b1371e4b09c82ec5ba65f2fb2 224 Gene3D G3DSA:3.30.530.20 62 224 3.3E-23 T 28-03-2018 IPR023393 START-like domain CP478_RS00490 a93c086b1371e4b09c82ec5ba65f2fb2 224 SUPERFAMILY SSF55961 77 220 2.65E-21 T 28-03-2018 CP478_RS00490 a93c086b1371e4b09c82ec5ba65f2fb2 224 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 77 216 1.2E-9 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS00695 8a69e600cc8e5d356e9490f15cd91d8e 455 Gene3D G3DSA:3.90.1200.10 248 430 1.4E-14 T 28-03-2018 CP478_RS00695 8a69e600cc8e5d356e9490f15cd91d8e 455 SUPERFAMILY SSF56112 244 418 3.5E-16 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS00695 8a69e600cc8e5d356e9490f15cd91d8e 455 SUPERFAMILY SSF56112 141 216 3.5E-16 T 28-03-2018 IPR011009 Protein kinase-like domain CP478_RS11245 f05f519f38b15f9fbe66fe938e602835 77 Gene3D G3DSA:1.10.1220.10 2 41 1.2E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS06455 249e9a63974eb01e6e195945a2dc7d41 189 SUPERFAMILY SSF46785 3 186 4.66E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06455 249e9a63974eb01e6e195945a2dc7d41 189 Gene3D G3DSA:1.10.10.10 1 92 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06455 249e9a63974eb01e6e195945a2dc7d41 189 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 1.7E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CP478_RS06455 249e9a63974eb01e6e195945a2dc7d41 189 Pfam PF10400 Virulence activator alpha C-term 105 186 8.0E-18 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 SUPERFAMILY SSF56770 9 152 4.45E-65 T 28-03-2018 CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.65 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.2E-24 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.4E-68 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17230 6c243ee931178bb11d1fefeed3d1db73 184 Gene3D G3DSA:3.40.50.700 12 170 8.5E-41 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CP478_RS17440 9badbab619d0e4a04fbbc4b55b1fcd39 115 ProDom PD030784 PRECURSOR SIGNAL TRANSCRIPTIONAL PROBABLE RV1990C/MT2044 REGULATORY MB3210 MB2012C 22 114 4.0E-36 T 28-03-2018 CP478_RS17440 9badbab619d0e4a04fbbc4b55b1fcd39 115 Gene3D G3DSA:1.10.260.40 13 106 8.4E-6 T 28-03-2018 CP478_RS17440 9badbab619d0e4a04fbbc4b55b1fcd39 115 Pfam PF09722 Protein of unknown function (DUF2384) 71 95 2.0E-4 T 28-03-2018 IPR024467 Domain of unknown function DUF2384 CP478_RS06110 ece9e8d1d784cb8011780ee2c0eab25e 232 Gene3D G3DSA:3.90.1720.10 23 138 1.2E-6 T 28-03-2018 CP478_RS06110 ece9e8d1d784cb8011780ee2c0eab25e 232 SUPERFAMILY SSF54001 23 125 3.34E-6 T 28-03-2018 CP478_RS16625 0ff1ea8fd449e1c3a6b99813dfe3858b 254 Gene3D G3DSA:3.90.226.10 9 245 2.5E-58 T 28-03-2018 CP478_RS16625 0ff1ea8fd449e1c3a6b99813dfe3858b 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 240 1.1E-45 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CP478_RS16625 0ff1ea8fd449e1c3a6b99813dfe3858b 254 SUPERFAMILY SSF52096 15 241 2.13E-59 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CP478_RS11095 712c02ec22ecbf268c014f88c3130975 280 Pfam PF11296 Protein of unknown function (DUF3097) 4 275 5.1E-120 T 28-03-2018 IPR021447 Protein of unknown function DUF3097 CP478_RS18960 2e6593445342acf105297267321dbf9d 202 Gene3D G3DSA:2.60.120.10 1 193 2.6E-67 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS18960 2e6593445342acf105297267321dbf9d 202 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 199 1.0E-114 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CP478_RS18960 2e6593445342acf105297267321dbf9d 202 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 180 5.2E-49 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CP478_RS18960 2e6593445342acf105297267321dbf9d 202 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 179 1.2E-61 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CP478_RS18960 2e6593445342acf105297267321dbf9d 202 SUPERFAMILY SSF51182 1 197 3.11E-72 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS19785 c32417540cbc95b2a8aa630655438279 240 Pfam PF04402 Protein of unknown function (DUF541) 38 237 9.8E-42 T 28-03-2018 IPR007497 Protein of unknown function DUF541 CP478_RS19785 c32417540cbc95b2a8aa630655438279 240 Gene3D G3DSA:3.40.190.10 6 212 2.5E-4 T 28-03-2018 CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 SUPERFAMILY SSF51735 2 252 2.01E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 4.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 Gene3D G3DSA:3.40.50.720 1 240 3.7E-46 T 28-03-2018 CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 6.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.3E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CP478_RS10235 bd60c9244113121f0ba497c2ba19c447 277 Pfam PF00106 short chain dehydrogenase 2 194 8.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CP478_RS16500 8a310f9c29db30169b2c8b7161320223 120 SUPERFAMILY SSF140453 5 80 1.18E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CP478_RS16500 8a310f9c29db30169b2c8b7161320223 120 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 2 63 3.0E-30 T 28-03-2018 CP478_RS16500 8a310f9c29db30169b2c8b7161320223 120 Gene3D G3DSA:1.10.287.1060 1 81 1.8E-4 T 28-03-2018 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 Pfam PF00171 Aldehyde dehydrogenase family 53 523 8.9E-93 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 540 2.6E-274 T 28-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 Gene3D G3DSA:3.40.309.10 312 504 8.4E-42 T 28-03-2018 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 SUPERFAMILY SSF53720 8 526 1.11E-116 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CP478_RS06505 7f85e533dc38349427ca831d81de1cdb 543 Gene3D G3DSA:3.40.605.10 36 311 2.3E-64 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CP478_RS04460 0bc2bf595e9c327677d63c625ec86361 684 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 254 428 1.5E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS04460 0bc2bf595e9c327677d63c625ec86361 684 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 253 429 9.6E-63 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CP478_RS04460 0bc2bf595e9c327677d63c625ec86361 684 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 557 641 1.2E-15 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CP478_RS09770 b10722d7ba3ad280877481fc42d9e992 300 Pfam PF14011 EspG family 14 283 5.6E-47 T 28-03-2018 IPR025734 EspG family CP478_RS05055 43bb9abbb77c98831b609f14f50269a5 358 SUPERFAMILY SSF51735 1 160 8.24E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CP478_RS05055 43bb9abbb77c98831b609f14f50269a5 358 Gene3D G3DSA:3.40.50.720 1 184 3.3E-15 T 28-03-2018 CP478_RS02225 73807c711c198071c73e262bfd359987 50 Pfam PF10825 Protein of unknown function (DUF2752) 9 47 3.3E-11 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 CP478_RS08445 f903fc8409e326342868d65781e37328 197 SUPERFAMILY SSF141488 120 194 5.1E-15 T 28-03-2018 IPR018660 C-type lysozyme inhibitor CP478_RS08445 f903fc8409e326342868d65781e37328 197 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 125 190 2.3E-13 T 28-03-2018 IPR018660 C-type lysozyme inhibitor CP478_RS08445 f903fc8409e326342868d65781e37328 197 Pfam PF07007 Lysozyme inhibitor LprI 42 110 1.6E-4 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CP478_RS05285 9e1fb8f350625d3d85e902c73081b168 98 Pfam PF07371 Protein of unknown function (DUF1490) 1 90 3.9E-38 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS05285 9e1fb8f350625d3d85e902c73081b168 98 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 94 5.0E-36 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS07870 56bb35b7f753866d2f8d946004a4a548 75 SUPERFAMILY SSF48498 7 72 6.29E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CP478_RS07870 56bb35b7f753866d2f8d946004a4a548 75 Gene3D G3DSA:1.10.357.10 4 75 8.8E-5 T 28-03-2018 CP478_RS20840 8c18a204cc0fba084fd88765ff882a1f 251 SMART SM00563 38 152 3.4E-37 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS20840 8c18a204cc0fba084fd88765ff882a1f 251 SUPERFAMILY SSF69593 12 202 1.96E-32 T 28-03-2018 CP478_RS20840 8c18a204cc0fba084fd88765ff882a1f 251 Gene3D G3DSA:3.40.1130.10 2 214 6.5E-44 T 28-03-2018 CP478_RS20840 8c18a204cc0fba084fd88765ff882a1f 251 Pfam PF01553 Acyltransferase 23 149 1.1E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 PRINTS PR01228 Eggshell protein signature 224 235 4.6E-7 T 28-03-2018 CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 PRINTS PR01228 Eggshell protein signature 353 371 4.6E-7 T 28-03-2018 CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 PRINTS PR01228 Eggshell protein signature 290 305 4.6E-7 T 28-03-2018 CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 PRINTS PR01228 Eggshell protein signature 321 331 4.6E-7 T 28-03-2018 CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 Pfam PF00934 PE family 1 93 3.3E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS11760 6855fd0a4f79140d2b33fea12f155de6 532 SUPERFAMILY SSF140459 8 84 5.49E-26 T 28-03-2018 CP478_RS10195 670c344d1ba57ffcb1f4132e9f171df6 70 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 4.8E-10 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CP478_RS15500 1aac7facd9a5c7b919af241a92edec75 275 SUPERFAMILY SSF161098 4 275 1.7E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS15500 1aac7facd9a5c7b919af241a92edec75 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 266 1.4E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS15500 1aac7facd9a5c7b919af241a92edec75 275 Gene3D G3DSA:1.10.3720.10 2 262 7.0E-39 T 28-03-2018 CP478_RS19250 87e60fd3081c0ad1b83624c245709cc5 354 SUPERFAMILY SSF53901 3 224 3.27E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19250 87e60fd3081c0ad1b83624c245709cc5 354 SUPERFAMILY SSF53901 252 342 3.71E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19250 87e60fd3081c0ad1b83624c245709cc5 354 Gene3D G3DSA:3.40.47.10 3 215 1.1E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS19250 87e60fd3081c0ad1b83624c245709cc5 354 Gene3D G3DSA:3.40.47.10 216 334 1.5E-7 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CP478_RS05240 991045c5b70ee0270642cd85b0af0077 73 SUPERFAMILY SSF47598 3 53 1.22E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS05240 991045c5b70ee0270642cd85b0af0077 73 Gene3D G3DSA:1.10.1220.10 1 71 2.1E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 Pfam PF10646 Sporulation and spore germination 168 290 1.7E-12 T 28-03-2018 IPR019606 GerMN domain CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 Gene3D G3DSA:2.130.10.120 76 529 5.2E-4 T 28-03-2018 CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 Hamap MF_01373 Lipoprotein LpqB [lpqB]. 1 583 25.545 T 28-03-2018 IPR023959 Lipoprotein LpqB CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 SMART SM00909 195 293 2.9E-15 T 28-03-2018 IPR019606 GerMN domain CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 SUPERFAMILY SSF69304 322 523 2.88E-5 T 28-03-2018 CP478_RS17790 109a7567676e8ff7ae6628db06eabaf5 583 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 323 582 2.5E-70 T 28-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CP478_RS09840 0bf4767812d8998d858de83f02b902af 403 Pfam PF00823 PPE family 10 165 8.9E-63 T 28-03-2018 IPR000030 PPE family CP478_RS09840 0bf4767812d8998d858de83f02b902af 403 SUPERFAMILY SSF140459 6 177 3.14E-64 T 28-03-2018 CP478_RS09840 0bf4767812d8998d858de83f02b902af 403 Gene3D G3DSA:1.10.287.1060 26 109 1.5E-4 T 28-03-2018 CP478_RS09840 0bf4767812d8998d858de83f02b902af 403 Pfam PF12484 Polymorphic PE/PPE proteins C terminal 321 399 5.4E-21 T 28-03-2018 IPR022171 PPE family, C-terminal CP478_RS01930 1d9c84dccb6e9d98591d455493b52bd2 275 Gene3D G3DSA:3.10.450.50 158 275 2.3E-5 T 28-03-2018 CP478_RS01930 1d9c84dccb6e9d98591d455493b52bd2 275 SUPERFAMILY SSF54427 164 270 8.26E-5 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS07440 f00fc1ffdb52ff8b4c251fd860d8356f 263 Gene3D G3DSA:3.40.630.30 13 247 2.4E-6 T 28-03-2018 CP478_RS07015 7500f377d87348cf30df592b40594204 325 SUPERFAMILY SSF161098 91 159 2.78E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07015 7500f377d87348cf30df592b40594204 325 SUPERFAMILY SSF161098 187 306 2.78E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07015 7500f377d87348cf30df592b40594204 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 323 4.7E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS07015 7500f377d87348cf30df592b40594204 325 Gene3D G3DSA:1.10.3720.10 1 312 6.4E-38 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 PRINTS PR01228 Eggshell protein signature 300 315 3.4E-5 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 PRINTS PR01228 Eggshell protein signature 331 341 3.4E-5 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 PRINTS PR01228 Eggshell protein signature 229 240 3.4E-5 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 PRINTS PR01228 Eggshell protein signature 365 383 3.4E-5 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 SUPERFAMILY SSF140459 8 84 2.62E-25 T 28-03-2018 CP478_RS18545 370c5710b9bb5628768d9f6be39cb5d3 731 Pfam PF00934 PE family 1 92 3.2E-34 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS16770 e7241767e9ea4802ed7edbb1cc380071 107 SUPERFAMILY SSF103481 4 105 6.41E-16 T 28-03-2018 CP478_RS16770 e7241767e9ea4802ed7edbb1cc380071 107 Pfam PF00893 Small Multidrug Resistance protein 3 94 1.1E-28 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CP478_RS20145 381d4ec882fe051de4ecfcee640fefd2 154 Gene3D G3DSA:1.10.10.410 94 154 3.2E-12 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CP478_RS20145 381d4ec882fe051de4ecfcee640fefd2 154 SUPERFAMILY SSF89095 4 154 9.42E-32 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CP478_RS20145 381d4ec882fe051de4ecfcee640fefd2 154 Gene3D G3DSA:1.10.1510.10 2 93 2.7E-26 T 28-03-2018 CP478_RS20145 381d4ec882fe051de4ecfcee640fefd2 154 Pfam PF09424 Yqey-like protein 5 154 1.6E-45 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CP478_RS14300 4def2a418d78ac195477cf80bc24b14d 378 SUPERFAMILY SSF53756 2 368 1.77E-71 T 28-03-2018 CP478_RS14300 4def2a418d78ac195477cf80bc24b14d 378 Gene3D G3DSA:3.40.50.2000 1 181 7.9E-12 T 28-03-2018 CP478_RS14300 4def2a418d78ac195477cf80bc24b14d 378 Pfam PF13692 Glycosyl transferases group 1 189 333 9.8E-31 T 28-03-2018 CP478_RS14300 4def2a418d78ac195477cf80bc24b14d 378 Gene3D G3DSA:3.40.50.2000 182 351 6.4E-40 T 28-03-2018 CP478_RS14300 4def2a418d78ac195477cf80bc24b14d 378 Pfam PF13439 Glycosyltransferase Family 4 14 173 5.0E-24 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CP478_RS09500 6d63a6c553d1a221af222c40d99864cb 82 SUPERFAMILY SSF88723 2 49 5.89E-5 T 28-03-2018 IPR029060 PIN domain-like CP478_RS09500 6d63a6c553d1a221af222c40d99864cb 82 Gene3D G3DSA:3.40.50.1010 1 69 7.3E-5 T 28-03-2018 IPR029060 PIN domain-like CP478_RS03010 89a723ae0c96d5df725100e126222714 286 Hamap MF_00188 Protease HtpX [htpX]. 9 283 28.653 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CP478_RS03010 89a723ae0c96d5df725100e126222714 286 Pfam PF01435 Peptidase family M48 69 283 1.2E-36 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CP478_RS03010 89a723ae0c96d5df725100e126222714 286 Gene3D G3DSA:3.30.2010.10 60 153 5.4E-22 T 28-03-2018 CP478_RS12450 ee115bae56e0c9e15774d930efa61d0f 74 Gene3D G3DSA:3.40.50.1580 1 74 5.1E-10 T 28-03-2018 CP478_RS12450 ee115bae56e0c9e15774d930efa61d0f 74 SUPERFAMILY SSF53167 3 71 6.4E-10 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS12450 ee115bae56e0c9e15774d930efa61d0f 74 Pfam PF01048 Phosphorylase superfamily 4 68 2.6E-8 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CP478_RS17925 34f99d0def8459ddc01dc764f0b67f62 93 Pfam PF07371 Protein of unknown function (DUF1490) 1 87 4.0E-42 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS17925 34f99d0def8459ddc01dc764f0b67f62 93 ProDom PD020015 MB2016C IRON REGULATED MB3297 RV1993C/MT2049 RV0968/MT0996 IRP10 ML0748 MB0993 1 84 1.0E-39 T 28-03-2018 IPR009963 Protein of unknown function DUF1490 CP478_RS02830 c40138812823bc336312218c38eea18b 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 85 321 1.2E-76 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CP478_RS02830 c40138812823bc336312218c38eea18b 324 Pfam PF01578 Cytochrome C assembly protein 107 318 5.7E-45 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CP478_RS02830 c40138812823bc336312218c38eea18b 324 Gene3D G3DSA:1.10.287.70 10 317 0.17 T 28-03-2018 CP478_RS10535 d9f2ed240f5b154a35641fd0007795fe 369 Pfam PF00296 Luciferase-like monooxygenase 1 322 7.2E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS10535 d9f2ed240f5b154a35641fd0007795fe 369 SUPERFAMILY SSF51679 1 357 1.11E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS10535 d9f2ed240f5b154a35641fd0007795fe 369 Gene3D G3DSA:3.20.20.30 1 361 1.4E-71 T 28-03-2018 CP478_RS11865 fb07d3c12170092bb06158326381c677 247 SMART SM00563 35 154 1.1E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS11865 fb07d3c12170092bb06158326381c677 247 Gene3D G3DSA:3.40.1130.10 2 229 1.5E-53 T 28-03-2018 CP478_RS11865 fb07d3c12170092bb06158326381c677 247 SUPERFAMILY SSF69593 2 217 5.89E-57 T 28-03-2018 CP478_RS11865 fb07d3c12170092bb06158326381c677 247 Pfam PF01553 Acyltransferase 21 151 4.0E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CP478_RS08660 e923e3675e57ae2add72c052e1d341c4 471 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 135 437 4.8E-113 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CP478_RS08660 e923e3675e57ae2add72c052e1d341c4 471 Gene3D G3DSA:3.40.50.300 154 367 3.3E-7 T 28-03-2018 CP478_RS08660 e923e3675e57ae2add72c052e1d341c4 471 SUPERFAMILY SSF52540 156 362 5.84E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS08660 e923e3675e57ae2add72c052e1d341c4 471 Pfam PF08706 D5 N terminal like 41 186 9.2E-33 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CP478_RS08660 e923e3675e57ae2add72c052e1d341c4 471 SMART SM00885 41 186 2.7E-45 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CP478_RS14405 6c41b019c5878f9359f44b456702b112 179 Pfam PF01951 Archease protein family (MTH1598/TM1083) 49 179 1.6E-19 T 28-03-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 CP478_RS14405 6c41b019c5878f9359f44b456702b112 179 SUPERFAMILY SSF69819 46 179 3.4E-26 T 28-03-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 CP478_RS14405 6c41b019c5878f9359f44b456702b112 179 Gene3D G3DSA:3.55.10.10 45 179 1.5E-22 T 28-03-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 CP478_RS04025 ce34a898c9b8325c6e4435378f656efe 175 SUPERFAMILY SSF140459 8 84 3.66E-25 T 28-03-2018 CP478_RS04025 ce34a898c9b8325c6e4435378f656efe 175 Pfam PF00934 PE family 2 93 6.0E-35 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS06105 56eafc155117a713111e7c03c9f6950d 124 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 119 13.287 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS06105 56eafc155117a713111e7c03c9f6950d 124 Pfam PF01850 PIN domain 2 111 3.0E-8 T 28-03-2018 IPR002716 PIN domain CP478_RS06105 56eafc155117a713111e7c03c9f6950d 124 SUPERFAMILY SSF88723 2 117 8.41E-14 T 28-03-2018 IPR029060 PIN domain-like CP478_RS06105 56eafc155117a713111e7c03c9f6950d 124 Gene3D G3DSA:3.40.50.1010 1 123 3.6E-15 T 28-03-2018 IPR029060 PIN domain-like CP478_RS18200 465e3ffebe9da0aadad553e7145d5358 204 Gene3D G3DSA:3.40.50.150 5 182 6.8E-19 T 28-03-2018 CP478_RS18200 465e3ffebe9da0aadad553e7145d5358 204 SUPERFAMILY SSF53335 18 152 5.16E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18200 465e3ffebe9da0aadad553e7145d5358 204 Pfam PF13649 Methyltransferase domain 51 140 1.2E-7 T 28-03-2018 CP478_RS06755 d5ee2eb1e29fb072abf743dae7a08de4 198 Pfam PF13828 Domain of unknown function (DUF4190) 132 192 1.6E-17 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CP478_RS10645 0648fbc53c58f55ae7696a405927bbeb 181 SUPERFAMILY SSF54611 71 161 1.29E-7 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CP478_RS10645 0648fbc53c58f55ae7696a405927bbeb 181 Gene3D G3DSA:3.10.420.10 17 163 1.4E-13 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CP478_RS14415 b2540d625cc412cdb5dc2e76f2d138af 93 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 9 87 7.0E-40 T 28-03-2018 IPR015057 Protein of unknown function DUF1876 CP478_RS14415 b2540d625cc412cdb5dc2e76f2d138af 93 Pfam PF08962 Domain of unknown function (DUF1876) 9 88 4.9E-30 T 28-03-2018 IPR015057 Protein of unknown function DUF1876 CP478_RS14415 b2540d625cc412cdb5dc2e76f2d138af 93 SUPERFAMILY SSF143212 5 87 7.98E-31 T 28-03-2018 CP478_RS17625 8d904b6ce5db7a99cd79e1f1b5abbdcf 372 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 114 368 3.2E-74 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CP478_RS17625 8d904b6ce5db7a99cd79e1f1b5abbdcf 372 Gene3D G3DSA:3.60.120.10 24 371 3.2E-91 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS17625 8d904b6ce5db7a99cd79e1f1b5abbdcf 372 SUPERFAMILY SSF56322 32 369 9.16E-86 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CP478_RS17625 8d904b6ce5db7a99cd79e1f1b5abbdcf 372 Pfam PF00425 chorismate binding enzyme 97 360 1.0E-69 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CP478_RS01400 8e2efc84b116f708d5dba0a91afa1b17 247 Gene3D G3DSA:3.40.50.1400 2 116 3.9E-23 T 28-03-2018 CP478_RS01400 8e2efc84b116f708d5dba0a91afa1b17 247 Gene3D G3DSA:3.40.50.1400 117 236 6.7E-16 T 28-03-2018 CP478_RS01400 8e2efc84b116f708d5dba0a91afa1b17 247 Pfam PF01903 CbiX 8 104 7.2E-17 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CP478_RS01400 8e2efc84b116f708d5dba0a91afa1b17 247 Pfam PF01903 CbiX 124 220 5.2E-6 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CP478_RS01400 8e2efc84b116f708d5dba0a91afa1b17 247 SUPERFAMILY SSF53800 3 226 2.86E-26 T 28-03-2018 CP478_RS01475 c4591f310352618625ff9aa51466afe3 193 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 163 1.5E-23 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CP478_RS01475 c4591f310352618625ff9aa51466afe3 193 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 141 162 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CP478_RS01475 c4591f310352618625ff9aa51466afe3 193 SUPERFAMILY SSF54593 12 172 2.28E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS01475 c4591f310352618625ff9aa51466afe3 193 Gene3D G3DSA:3.10.180.10 9 193 1.5E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04945 cba98e57eb10484ef87e306b8d90b772 516 Pfam PF00144 Beta-lactamase 47 383 1.9E-60 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS04945 cba98e57eb10484ef87e306b8d90b772 516 Gene3D G3DSA:3.40.710.10 39 392 9.0E-70 T 28-03-2018 CP478_RS04945 cba98e57eb10484ef87e306b8d90b772 516 SUPERFAMILY SSF56601 41 390 2.91E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS04945 cba98e57eb10484ef87e306b8d90b772 516 Pfam PF11954 Domain of unknown function (DUF3471) 423 496 6.5E-13 T 28-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal CP478_RS13960 ebcae72e8ca7961db823928e9b2f6c1d 85 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 38 1.3E-11 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CP478_RS13960 ebcae72e8ca7961db823928e9b2f6c1d 85 SUPERFAMILY SSF47598 2 37 4.13E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS13960 ebcae72e8ca7961db823928e9b2f6c1d 85 Gene3D G3DSA:1.10.1220.10 1 39 8.8E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS14350 a48280471255bd2e892a0fbe9b823e92 117 Gene3D G3DSA:2.60.120.10 7 113 4.4E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CP478_RS14350 a48280471255bd2e892a0fbe9b823e92 117 SUPERFAMILY SSF51182 18 105 6.93E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain CP478_RS10950 d15cb8e4eb807d9c637a509bbcd6eb55 80 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 7 48 3.7E-17 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS19745 7ce5e97bac1e2ce4a865e9cb5ec5c92c 392 Gene3D G3DSA:1.20.5.1230 31 236 1.4E-7 T 28-03-2018 CP478_RS05610 6ea422c1ab28bc7562a37752b7d513a4 155 Pfam PF04417 Protein of unknown function (DUF501) 17 136 1.1E-33 T 28-03-2018 IPR007511 Protein of unknown function DUF501 CP478_RS14980 393c4bb295e02356fadb5cd3b684606a 284 Pfam PF07505 Protein of unknown function (DUF5131) 5 243 1.1E-96 T 28-03-2018 IPR011101 Protein of unknown function DUF5131 CP478_RS05210 8870c2397dc5d2d95c5a06034c495c0c 303 Pfam PF17270 Family of unknown function (DUF5336) 8 169 9.6E-58 T 28-03-2018 IPR035166 Protein of unknown function DUF5336 CP478_RS05210 8870c2397dc5d2d95c5a06034c495c0c 303 ProDom PD026943 MEMBRANE ANTIGEN TRANSMEMBRANE ANTIGENIC HOMOLOG PRECURSOR MLCB373.06 SIGNAL 1 169 5.0E-43 T 28-03-2018 IPR035166 Protein of unknown function DUF5336 CP478_RS00625 093e40c3a2d2b99991219ce547e4a0c7 190 SUPERFAMILY SSF56784 9 177 1.32E-28 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00625 093e40c3a2d2b99991219ce547e4a0c7 190 Gene3D G3DSA:3.40.50.1000 11 183 9.1E-17 T 28-03-2018 IPR023214 HAD-like domain CP478_RS00625 093e40c3a2d2b99991219ce547e4a0c7 190 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 10 153 7.4E-53 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CP478_RS00625 093e40c3a2d2b99991219ce547e4a0c7 190 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 10 156 6.9E-36 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CP478_RS14910 e34d3e68de52c97d78a064d8a03badf8 699 Pfam PF08310 LGFP repeat 112 168 1.5E-9 T 28-03-2018 IPR013207 LGFP CP478_RS14910 e34d3e68de52c97d78a064d8a03badf8 699 Pfam PF08310 LGFP repeat 60 107 2.9E-6 T 28-03-2018 IPR013207 LGFP CP478_RS14910 e34d3e68de52c97d78a064d8a03badf8 699 Pfam PF08310 LGFP repeat 245 289 1.1E-9 T 28-03-2018 IPR013207 LGFP CP478_RS14910 e34d3e68de52c97d78a064d8a03badf8 699 Pfam PF08310 LGFP repeat 294 350 1.1E-9 T 28-03-2018 IPR013207 LGFP CP478_RS16225 fd53de9346612f18feb73c8e08c378f5 210 Pfam PF07884 Vitamin K epoxide reductase family 24 156 2.2E-32 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CP478_RS16225 fd53de9346612f18feb73c8e08c378f5 210 SMART SM00756 19 160 5.3E-62 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CP478_RS06355 094168551e55f51ef1609389f286f3ec 371 PRINTS PR01218 Pistil-specific extensin-like signature 211 229 1.6E-5 T 28-03-2018 IPR003882 Pistil-specific extensin-like protein GO:0005199 CP478_RS06355 094168551e55f51ef1609389f286f3ec 371 PRINTS PR01218 Pistil-specific extensin-like signature 178 201 1.6E-5 T 28-03-2018 IPR003882 Pistil-specific extensin-like protein GO:0005199 CP478_RS16595 ae0364961bb6786c545b5236f89613ee 182 Pfam PF14230 Domain of unknown function (DUF4333) 106 167 7.8E-13 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CP478_RS16595 ae0364961bb6786c545b5236f89613ee 182 Pfam PF14230 Domain of unknown function (DUF4333) 23 97 2.9E-22 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CP478_RS16595 ae0364961bb6786c545b5236f89613ee 182 Gene3D G3DSA:2.40.10.220 60 124 0.053 T 28-03-2018 CP478_RS12750 c5cb1bd385250b5904b32e688b565dc2 318 Pfam PF00899 ThiF family 27 282 5.3E-54 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS12750 c5cb1bd385250b5904b32e688b565dc2 318 SUPERFAMILY SSF69572 23 278 8.24E-50 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CP478_RS12750 c5cb1bd385250b5904b32e688b565dc2 318 Gene3D G3DSA:3.40.50.720 19 285 5.4E-41 T 28-03-2018 CP478_RS02420 132f3f0d115363656b5152526f754a71 148 Pfam PF16877 Domain of unknown function (DUF5078) 33 147 4.1E-55 T 28-03-2018 IPR031702 Protein of unknown function DUF5078 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 SUPERFAMILY SSF140459 8 84 1.33E-25 T 28-03-2018 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 PRINTS PR01228 Eggshell protein signature 303 314 1.1E-5 T 28-03-2018 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 PRINTS PR01228 Eggshell protein signature 443 461 1.1E-5 T 28-03-2018 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 PRINTS PR01228 Eggshell protein signature 368 383 1.1E-5 T 28-03-2018 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 PRINTS PR01228 Eggshell protein signature 396 406 1.1E-5 T 28-03-2018 CP478_RS13600 1a7bca4e29732d1743b994cd6bdf9e56 694 Pfam PF00934 PE family 2 93 9.6E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS15630 3cd0c6bfa3848aa80dddd04fd0e4ca2f 308 Gene3D G3DSA:3.40.50.880 62 308 1.1E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS15630 3cd0c6bfa3848aa80dddd04fd0e4ca2f 308 Pfam PF07722 Peptidase C26 66 279 3.1E-69 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CP478_RS15630 3cd0c6bfa3848aa80dddd04fd0e4ca2f 308 SUPERFAMILY SSF52317 91 298 7.18E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CP478_RS18860 092a04b6dae34d1e5d4dee9e95b60bd2 404 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 233 402 5.0E-45 T 28-03-2018 IPR023840 Type VII secretion system Rv3446c CP478_RS09825 34117bc5ddd89910c56b9c1836e4cd16 108 Pfam PF05305 Protein of unknown function (DUF732) 10 100 1.4E-25 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 Gene3D G3DSA:1.10.10.10 2 104 7.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 6.0E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 6.0E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 6.0E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 SUPERFAMILY SSF46785 6 99 5.25E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 SMART SM00418 9 87 1.7E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS11100 7da85f5d6cf73a6adc9ac1bbf9a1ccf0 107 Pfam PF01022 Bacterial regulatory protein, arsR family 16 60 3.6E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CP478_RS11125 30b7c1104ae3c0704260852d370a2cce 280 SUPERFAMILY SSF161098 10 277 1.96E-74 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS11125 30b7c1104ae3c0704260852d370a2cce 280 Gene3D G3DSA:1.10.3720.10 5 267 5.7E-48 T 28-03-2018 CP478_RS11125 30b7c1104ae3c0704260852d370a2cce 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 273 4.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS16975 736d9fce4aaa5fb5ad344ab55c632342 297 PIRSF PIRSF003097 1 297 2.2E-56 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CP478_RS16975 736d9fce4aaa5fb5ad344ab55c632342 297 Pfam PF02687 FtsX-like permease family 200 292 4.2E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CP478_RS07545 9204ffc7c4a763648d6bf7e0b3514330 497 Pfam PF07812 TfuA-like protein 53 172 1.1E-42 T 28-03-2018 IPR012924 TfuA-like, core CP478_RS07545 9204ffc7c4a763648d6bf7e0b3514330 497 PIRSF PIRSF026633 1 497 0.0 T 28-03-2018 IPR016845 Uncharacterised conserved protein UCP026633, TfuA-like, mycobacteria CP478_RS04715 ee7d12c33516f46e8123a9f90633c521 167 Pfam PF01967 MoaC family 26 159 3.4E-53 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS04715 ee7d12c33516f46e8123a9f90633c521 167 SUPERFAMILY SSF55040 22 164 8.11E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS04715 ee7d12c33516f46e8123a9f90633c521 167 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 15 161 3.7E-66 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS04715 ee7d12c33516f46e8123a9f90633c521 167 Gene3D G3DSA:3.30.70.640 13 167 1.1E-63 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CP478_RS04715 ee7d12c33516f46e8123a9f90633c521 167 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 13 167 35.64 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CP478_RS13320 b88062b654fa0210795a8a815d2aae3c 139 Pfam PF04191 Phospholipid methyltransferase 22 116 1.8E-11 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CP478_RS06720 63949536241a3acb27ec047476069e2c 177 Pfam PF03703 Bacterial PH domain 87 165 6.4E-16 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CP478_RS04505 927471904e18e64279679bd40c1db054 271 TIGRFAM TIGR04255 sporadTIGR04255: TIGR04255 family protein 12 268 6.9E-46 T 28-03-2018 IPR026349 Conserved hypothetical protein CHP04255 CP478_RS21215 b8d412669782c346317f21ef3a8c7b47 460 Gene3D G3DSA:1.10.287.1060 132 223 0.016 T 28-03-2018 CP478_RS21215 b8d412669782c346317f21ef3a8c7b47 460 Gene3D G3DSA:1.10.287.1060 2 94 0.0024 T 28-03-2018 CP478_RS21215 b8d412669782c346317f21ef3a8c7b47 460 SUPERFAMILY SSF140459 142 266 3.66E-5 T 28-03-2018 CP478_RS15645 b34ab37643d735f65001a5a38cbd46fe 194 Gene3D G3DSA:3.30.70.260 3 64 0.0014 T 28-03-2018 CP478_RS15645 b34ab37643d735f65001a5a38cbd46fe 194 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 4.5E-16 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CP478_RS09835 91bfb7bca977c3d66646231971ff5e43 99 Pfam PF00934 PE family 1 93 7.3E-27 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS09835 91bfb7bca977c3d66646231971ff5e43 99 SUPERFAMILY SSF140459 8 84 6.54E-20 T 28-03-2018 CP478_RS00150 694374b5a02126b6b291134825ef3026 448 Pfam PF10774 Domain of unknown function (DUF4226) 75 184 1.5E-36 T 28-03-2018 IPR019710 Protein of unknown function DUF4226 CP478_RS16295 6691b1d76b08581e9980cc705bec5937 181 Pfam PF12028 Protein of unknown function (DUF3515) 18 174 4.5E-54 T 28-03-2018 IPR021903 Protein of unknown function DUF3515 CP478_RS21220 3141d16f474f720d7b9e088e98067308 462 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 177 266 1.4E-19 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS21220 3141d16f474f720d7b9e088e98067308 462 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 19 333 2.1E-91 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 Gene3D G3DSA:3.50.50.60 37 119 2.9E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 Gene3D G3DSA:3.50.50.60 171 371 1.6E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 339 1.1E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 SUPERFAMILY SSF51905 8 350 1.46E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 Gene3D G3DSA:3.50.50.60 1 36 6.7E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 2.3E-8 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.3E-8 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 2.3E-8 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 6.6E-11 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 6.6E-11 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 6.6E-11 T 28-03-2018 CP478_RS10080 b99b2b8065d51673d5943d090c769483 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 6.6E-11 T 28-03-2018 CP478_RS07315 e6051b48872466456aa69a136d55140d 146 SMART SM00232 10 140 1.1E-32 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CP478_RS07315 e6051b48872466456aa69a136d55140d 146 Pfam PF14464 Prokaryotic homologs of the JAB domain 15 129 4.2E-26 T 28-03-2018 IPR028090 JAB domain, prokaryotic CP478_RS07315 e6051b48872466456aa69a136d55140d 146 SUPERFAMILY SSF102712 9 139 2.75E-28 T 28-03-2018 CP478_RS07315 e6051b48872466456aa69a136d55140d 146 Gene3D G3DSA:3.40.140.10 9 146 1.4E-27 T 28-03-2018 CP478_RS04605 14ed9d77b94496a8a7d87f9390312a9d 334 SUPERFAMILY SSF52518 11 314 8.84E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CP478_RS04605 14ed9d77b94496a8a7d87f9390312a9d 334 Pfam PF00676 Dehydrogenase E1 component 42 312 4.5E-40 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CP478_RS04605 14ed9d77b94496a8a7d87f9390312a9d 334 Gene3D G3DSA:3.40.50.970 4 311 1.8E-43 T 28-03-2018 CP478_RS01295 8746cb6dd663674ad05f01dda8b63dc4 77 Gene3D G3DSA:1.10.1220.10 1 42 5.4E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS04595 c5272d2ae648add1465200bf38a7f784 80 Gene3D G3DSA:1.20.1250.20 1 80 4.6E-4 T 28-03-2018 CP478_RS14945 674066c225199797656f08c614e5a1c0 231 Gene3D G3DSA:3.40.830.10 59 231 8.7E-13 T 28-03-2018 CP478_RS04545 56e451f7ad2b60775fefbead42b5bcbe 882 SUPERFAMILY SSF140459 8 82 1.78E-24 T 28-03-2018 CP478_RS04545 56e451f7ad2b60775fefbead42b5bcbe 882 Pfam PF00934 PE family 1 93 4.4E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS03110 7928827a1f83e46263932dc30a818c05 163 Gene3D G3DSA:2.30.110.10 16 160 2.0E-9 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS03110 7928827a1f83e46263932dc30a818c05 163 PIRSF PIRSF021513 4 163 1.5E-90 T 28-03-2018 IPR016791 Rubromycin-type polyketide biosynthesis protein, GrhN/RubW, predicted CP478_RS10270 ee4e76229386b618b5bbb088a722e881 239 Pfam PF14333 Domain of unknown function (DUF4389) 158 210 5.6E-8 T 28-03-2018 IPR025498 Protein of unknown function DUF4389 CP478_RS10270 ee4e76229386b618b5bbb088a722e881 239 Pfam PF14333 Domain of unknown function (DUF4389) 22 95 6.9E-13 T 28-03-2018 IPR025498 Protein of unknown function DUF4389 CP478_RS02395 c884c887ae6bdb3b3b51458486ef5d40 140 Pfam PF05423 Mycobacterium membrane protein 2 140 8.2E-75 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS19815 13ee273a58424ac3db1cefa34b3adcb2 365 Pfam PF04332 Protein of unknown function (DUF475) 45 355 1.2E-142 T 28-03-2018 IPR007427 Protein of unknown function DUF475 CP478_RS04635 13a2ed610b22b7e4a024414577ce36e1 419 Gene3D G3DSA:1.20.1250.20 201 400 5.8E-10 T 28-03-2018 CP478_RS04635 13a2ed610b22b7e4a024414577ce36e1 419 Pfam PF07690 Major Facilitator Superfamily 18 314 3.3E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CP478_RS04635 13a2ed610b22b7e4a024414577ce36e1 419 SUPERFAMILY SSF103473 12 400 9.29E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CP478_RS04635 13a2ed610b22b7e4a024414577ce36e1 419 Gene3D G3DSA:1.20.1250.20 3 200 9.8E-27 T 28-03-2018 CP478_RS08075 54b24a7795d006ae95af9fb89479dd7e 63 Gene3D G3DSA:1.10.10.10 1 45 1.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06760 e6951a03b32c4b37220205a6216fec96 175 Gene3D G3DSA:1.20.1250.20 20 150 2.4E-4 T 28-03-2018 CP478_RS04705 9cb513564c265a36b5bcd4527fb0eaf1 756 Gene3D G3DSA:1.10.10.10 570 704 0.17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS04705 9cb513564c265a36b5bcd4527fb0eaf1 756 Pfam PF13625 Helicase conserved C-terminal domain 479 601 4.6E-38 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CP478_RS04705 9cb513564c265a36b5bcd4527fb0eaf1 756 Gene3D G3DSA:1.10.10.10 238 348 0.13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 PIRSF PIRSF017269 1 271 5.4E-89 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 Gene3D G3DSA:3.40.50.150 69 266 3.9E-40 T 28-03-2018 CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 SUPERFAMILY SSF53335 7 260 6.86E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 Gene3D G3DSA:3.10.330.20 7 67 2.9E-21 T 28-03-2018 CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 73 237 7.9E-20 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CP478_RS11525 7242042998199f8cb149ddff260ccbdf 280 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 4 54 1.3E-25 T 28-03-2018 CP478_RS05605 99bdcf9fa46d46d92aa15ac7c9ffca9e 228 Pfam PF04977 Septum formation initiator 86 161 7.5E-19 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CP478_RS09930 48864822e0e18d74ebe9c4930446eea9 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 2.5E-33 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CP478_RS09930 48864822e0e18d74ebe9c4930446eea9 110 PIRSF PIRSF018579 1 110 2.8E-47 T 28-03-2018 IPR009709 Protein of unknown function DUF1290 CP478_RS02710 9cd6d591a4e44b673d7638726e9f2f54 147 Pfam PF05423 Mycobacterium membrane protein 10 146 4.0E-64 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS01560 7e6f1ab9ba8b810346329f55a56f4c21 295 Pfam PF14011 EspG family 11 269 4.7E-65 T 28-03-2018 IPR025734 EspG family CP478_RS01545 3657a1fc61ef8d0c90af9c5547407da4 513 Gene3D G3DSA:1.10.287.1060 23 113 9.2E-6 T 28-03-2018 CP478_RS01545 3657a1fc61ef8d0c90af9c5547407da4 513 Pfam PF00823 PPE family 8 164 4.9E-61 T 28-03-2018 IPR000030 PPE family CP478_RS01545 3657a1fc61ef8d0c90af9c5547407da4 513 SUPERFAMILY SSF140459 5 177 6.8E-62 T 28-03-2018 CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 SUPERFAMILY SSF140459 8 83 3.66E-24 T 28-03-2018 CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 Pfam PF00934 PE family 1 93 6.6E-33 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 PRINTS PR01228 Eggshell protein signature 301 311 2.3E-9 T 28-03-2018 CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 PRINTS PR01228 Eggshell protein signature 333 351 2.3E-9 T 28-03-2018 CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 PRINTS PR01228 Eggshell protein signature 273 288 2.3E-9 T 28-03-2018 CP478_RS18440 e0539001fea037c7cfa5f7bad17dda82 588 PRINTS PR01228 Eggshell protein signature 183 194 2.3E-9 T 28-03-2018 CP478_RS20415 d1b3a7a5b97f854bab9bca56cb283060 529 Pfam PF12821 Threonine/Serine exporter, ThrE 323 447 1.2E-13 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CP478_RS20415 d1b3a7a5b97f854bab9bca56cb283060 529 Pfam PF06738 Putative threonine/serine exporter 49 287 4.4E-63 T 28-03-2018 IPR010619 Putative threonine/serine exporter CP478_RS14560 618db6ab093cc2441e7da7c309361dfb 475 Pfam PF12307 Protein of unknown function (DUF3631) 195 375 5.6E-62 T 28-03-2018 IPR022081 Domain of unknown function DUF3631 CP478_RS06340 a0902233525a52149f9111cdf21cfb1d 62 Pfam PF17227 Family of unknown function (DUF5302) 12 62 2.0E-21 T 28-03-2018 IPR035172 Protein of unknown function DUF5302 CP478_RS00700 ec52425c1ccf95caea4c3883b41a16e2 259 Pfam PF06912 Protein of unknown function (DUF1275) 13 212 1.5E-26 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 CP478_RS20990 7ac33fd848d955bf6839f0af7986db31 342 Pfam PF14219 Domain of unknown function (DUF4328) 153 305 6.2E-28 T 28-03-2018 IPR025565 Domain of unknown function DUF4328 CP478_RS20715 db64c24a7b4178d4f85ffe26a797d0f8 643 Pfam PF12250 Arabinofuranosyltransferase N terminal 31 453 1.9E-168 T 28-03-2018 IPR020963 Arabinofuranosyltransferase AftA, N-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 CP478_RS20715 db64c24a7b4178d4f85ffe26a797d0f8 643 Pfam PF12249 Arabinofuranosyltransferase A C terminal 465 637 3.2E-72 T 28-03-2018 IPR020959 Arabinofuranosyltransferase AftA, C-terminal GO:0005886|GO:0016021|GO:0016757|GO:0044038 CP478_RS06510 d59f225a9ecc908731f56afdb219aa74 329 PIRSF PIRSF000196 6 322 1.6E-112 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CP478_RS06510 d59f225a9ecc908731f56afdb219aa74 329 Gene3D G3DSA:3.20.20.220 6 329 3.3E-72 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CP478_RS06510 d59f225a9ecc908731f56afdb219aa74 329 Pfam PF01619 Proline dehydrogenase 52 312 6.4E-28 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CP478_RS06510 d59f225a9ecc908731f56afdb219aa74 329 SUPERFAMILY SSF51730 42 318 1.88E-71 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CP478_RS05455 c7b01d8cbd64df10285ebe551d72ed75 69 SUPERFAMILY SSF53335 1 68 2.08E-6 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15410 22c6f75fbfb14f18128516d8fc8fbe70 338 Pfam PF01867 CRISPR associated protein Cas1 4 283 2.5E-73 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CP478_RS15410 22c6f75fbfb14f18128516d8fc8fbe70 338 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 323 3.2E-95 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CP478_RS15410 22c6f75fbfb14f18128516d8fc8fbe70 338 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 316 22.796 T 28-03-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CP478_RS04210 41215cd0fa430d3ccd1e07684fc9eedf 303 Pfam PF00756 Putative esterase 87 260 6.2E-8 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CP478_RS04210 41215cd0fa430d3ccd1e07684fc9eedf 303 Gene3D G3DSA:3.40.50.1820 51 300 6.6E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS04210 41215cd0fa430d3ccd1e07684fc9eedf 303 SUPERFAMILY SSF53474 68 298 1.92E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS14450 efc259a6a019c2e57a1fb39a2e9281a5 148 Gene3D G3DSA:3.30.750.24 26 142 5.4E-12 T 28-03-2018 IPR002645 STAS domain CP478_RS14450 efc259a6a019c2e57a1fb39a2e9281a5 148 Pfam PF01740 STAS domain 39 137 8.2E-14 T 28-03-2018 IPR002645 STAS domain CP478_RS14450 efc259a6a019c2e57a1fb39a2e9281a5 148 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 29 136 6.0E-32 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CP478_RS14450 efc259a6a019c2e57a1fb39a2e9281a5 148 SUPERFAMILY SSF52091 39 138 1.28E-16 T 28-03-2018 IPR002645 STAS domain CP478_RS12110 bf13ee548c1e20c6358651ed0ae7abdb 233 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 65 232 5.2E-75 T 28-03-2018 IPR018655 Protein of unknown function DUF2086 CP478_RS12110 bf13ee548c1e20c6358651ed0ae7abdb 233 Gene3D G3DSA:2.60.120.620 18 233 4.5E-13 T 28-03-2018 CP478_RS04815 1511e03e36b7764bebdbb8a80a4f4746 253 Pfam PF11268 Protein of unknown function (DUF3071) 1 171 1.3E-59 T 28-03-2018 IPR021421 Protein of unknown function DUF3071 CP478_RS04915 54edfcabd01cd098d9ef3bbf7078ccfc 175 Gene3D G3DSA:3.40.10.10 49 173 4.3E-5 T 28-03-2018 IPR035451 Ada-like domain CP478_RS20875 a673114576521295851958153a4bcde6 404 Gene3D G3DSA:3.40.50.1820 65 292 2.1E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS20875 a673114576521295851958153a4bcde6 404 Pfam PF08237 PE-PPE domain 104 325 2.8E-70 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS06365 4a1e5f40cf4f4741d2bc2e3d91bf790c 431 Pfam PF09594 Glycosyltransferase family 87 103 334 1.6E-52 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CP478_RS00855 8aa5b8936590db38b5b637d039da1eef 110 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 93 3.8E-31 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CP478_RS06445 5c6e5319c130221fdb9cc553c7fe8899 110 TIGRFAM TIGR04529 MTB_hemophore: hemophore-related protein, Rv0203/Rv1174c family 39 110 2.8E-20 T 28-03-2018 IPR032407 Haemophore, haem-binding GO:0020037 CP478_RS06445 5c6e5319c130221fdb9cc553c7fe8899 110 PIRSF PIRSF010611 1 110 5.3E-48 T 28-03-2018 IPR016572 Uncharacterised conserved protein UCP010611 CP478_RS19545 08690292de2afd626510efc5c8a5e65e 237 Pfam PF14032 PknH-like extracellular domain 43 233 1.1E-51 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS00530 5b86e36e8d0f9deceb9f26b6d3d4f77a 136 ProDom PD008243 RV1792C/MT1741/MB1728C RV1945/MT1995 MB1980 MB0098C RV3466/MT3572 VERY RV1128C/MT1160 RV1148C/MT1183 MB1159C RV0095C 39 134 2.0E-26 T 28-03-2018 CP478_RS00530 5b86e36e8d0f9deceb9f26b6d3d4f77a 136 Pfam PF02720 Domain of unknown function (DUF222) 76 135 9.3E-8 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS06020 c97d5f374c67bb37566a7ed3d61bc3fe 291 SUPERFAMILY SSF88713 47 231 4.45E-60 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CP478_RS06020 c97d5f374c67bb37566a7ed3d61bc3fe 291 Pfam PF01522 Polysaccharide deacetylase 47 161 7.1E-34 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CP478_RS06020 c97d5f374c67bb37566a7ed3d61bc3fe 291 Gene3D G3DSA:3.20.20.370 35 236 2.8E-51 T 28-03-2018 CP478_RS11810 0fd560ef4bfeab9b646865f8d4b9bdef 301 Gene3D G3DSA:3.20.20.220 2 289 1.9E-18 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CP478_RS04060 4c734fc05e777efcd6283d13eac95f02 801 SUPERFAMILY SSF140459 8 84 2.88E-23 T 28-03-2018 CP478_RS04060 4c734fc05e777efcd6283d13eac95f02 801 Pfam PF00934 PE family 1 93 2.8E-32 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS16045 0752a29c064bda8bd3a0e527f2d27382 289 TIGRFAM TIGR00025 Mtu_efflux: ABC transporter efflux protein, DrrB family 50 289 6.8E-102 T 28-03-2018 IPR004377 ABC transporter, permease protein DrrB/DrrC GO:0042891|GO:0043215|GO:0046677|GO:1900753 CP478_RS16045 0752a29c064bda8bd3a0e527f2d27382 289 PIRSF PIRSF006648 8 289 3.1E-49 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CP478_RS07825 635029284d5a265d1bc04c0a502310f3 589 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 580 9.9E-266 T 28-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane CP478_RS01125 ffbc698a06f95a3b3ada3ea5c7918dda 242 Gene3D G3DSA:3.40.50.1010 32 206 8.9E-27 T 28-03-2018 IPR029060 PIN domain-like CP478_RS01125 ffbc698a06f95a3b3ada3ea5c7918dda 242 Pfam PF01936 NYN domain 39 202 1.3E-6 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type CP478_RS15305 b778793253b360bae8205093c346cc4c 187 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 31 176 2.9E-55 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CP478_RS10380 323a174c69ac52c6c83ef1eccfca59ef 215 Pfam PF14081 Domain of unknown function (DUF4262) 84 197 6.1E-32 T 28-03-2018 IPR025358 Protein of unknown function DUF4262 CP478_RS16125 1c5bc63c9aa93bc357276d190fb16e64 381 Gene3D G3DSA:3.20.20.30 22 373 1.6E-63 T 28-03-2018 CP478_RS16125 1c5bc63c9aa93bc357276d190fb16e64 381 Pfam PF00296 Luciferase-like monooxygenase 34 346 2.7E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16125 1c5bc63c9aa93bc357276d190fb16e64 381 SUPERFAMILY SSF51679 33 371 7.59E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CP478_RS16910 854a49bfee731a6183b0ea40f58f84b6 295 Pfam PF01145 SPFH domain / Band 7 family 56 245 1.2E-16 T 28-03-2018 IPR001107 Band 7 domain CP478_RS04560 5f02a78a578ffd5db3f13f82e0a43b65 217 PIRSF PIRSF021525 1 217 1.5E-106 T 28-03-2018 IPR014513 Uncharacterised conserved protein UCP021525 CP478_RS16440 7f096c803e532468197e218fb0f08bd9 279 Pfam PF07681 DoxX 114 194 1.7E-19 T 28-03-2018 IPR032808 DoxX family CP478_RS19000 cf79be5d05c01ca77d525ca1ac423321 168 Gene3D G3DSA:3.10.450.50 5 168 3.1E-39 T 28-03-2018 CP478_RS19000 cf79be5d05c01ca77d525ca1ac423321 168 Pfam PF13577 SnoaL-like domain 12 126 1.4E-25 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CP478_RS19000 cf79be5d05c01ca77d525ca1ac423321 168 SUPERFAMILY SSF54427 9 151 4.98E-40 T 28-03-2018 IPR032710 NTF2-like domain CP478_RS14420 f3ff23a8c89b1f6a2e131d911601e45a 161 Pfam PF01814 Hemerythrin HHE cation binding domain 3 116 7.0E-15 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CP478_RS14420 f3ff23a8c89b1f6a2e131d911601e45a 161 Gene3D G3DSA:1.20.120.520 2 154 4.1E-16 T 28-03-2018 CP478_RS00985 9a61e27bc05b8773f8ba93a1f8dedcd5 452 Pfam PF12051 Protein of unknown function (DUF3533) 32 403 2.1E-44 T 28-03-2018 IPR022703 Domain of unknown function DUF3533 CP478_RS00985 9a61e27bc05b8773f8ba93a1f8dedcd5 452 Gene3D G3DSA:3.40.1710.10 52 229 1.0E-22 T 28-03-2018 CP478_RS00950 ddb2762b386a79cb23913ec9089fad91 390 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 20 309 1.0E-90 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS00950 ddb2762b386a79cb23913ec9089fad91 390 Pfam PF02470 MlaD protein 51 124 2.8E-11 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS17760 44ce3dcbeb83cd22db14425f732e6a92 244 Pfam PF07298 NnrU protein 54 207 5.6E-6 T 28-03-2018 IPR009915 NnrU domain CP478_RS10725 95f460e165f009c412b48a1302603390 377 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 6 296 4.4E-89 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS10725 95f460e165f009c412b48a1302603390 377 Pfam PF02470 MlaD protein 40 111 2.1E-14 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS15470 ba37b2b6b0a1390db4700c796cf886a1 89 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 84 7.7E-34 T 28-03-2018 IPR018735 Protein of unknown function DUF2277 CP478_RS17590 82c243320845587de43ae002522241cf 90 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 1.1E-29 T 28-03-2018 IPR021456 Protein of unknown function DUF3107 CP478_RS02380 98e89b9be04e068f4582ffcac2abaf27 229 Pfam PF07103 Protein of unknown function (DUF1365) 1 229 7.6E-58 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 CP478_RS06160 81305418f0e9ea43e0ef0a78a924df7a 414 Pfam PF06974 Protein of unknown function (DUF1298) 270 413 9.1E-9 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CP478_RS06045 04355c94f23b56da5689693c085382ea 385 Pfam PF01594 AI-2E family transporter 13 345 6.3E-72 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CP478_RS08545 aee886aa99baeb072678daeb3b9262eb 72 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 7 49 1.2E-18 T 28-03-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB CP478_RS12330 2112002410b0960d472fed6b0b721f67 388 Pfam PF13469 Sulfotransferase family 82 325 1.2E-40 T 28-03-2018 CP478_RS12330 2112002410b0960d472fed6b0b721f67 388 Gene3D G3DSA:3.40.50.300 70 369 6.6E-35 T 28-03-2018 CP478_RS12330 2112002410b0960d472fed6b0b721f67 388 SUPERFAMILY SSF52540 79 136 2.32E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS12330 2112002410b0960d472fed6b0b721f67 388 SUPERFAMILY SSF52540 203 373 2.32E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS01680 2572d29320456c3e334d113ff5e46afa 220 Pfam PF11259 Protein of unknown function (DUF3060) 157 212 5.5E-23 T 28-03-2018 IPR021417 Protein of unknown function DUF3060 CP478_RS00925 0bfe1861dcaf550019cda51037c2c2e5 289 Pfam PF02405 Permease MlaE 70 275 3.4E-50 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS07355 a07a598aba82b1e9250c8ec9c467c404 120 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 28 108 2.7E-23 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CP478_RS07355 a07a598aba82b1e9250c8ec9c467c404 120 Pfam PF12823 Domain of unknown function (DUF3817) 28 109 9.9E-23 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CP478_RS04735 2bfc320f3147eb90114fa0e32adf815b 92 Pfam PF02597 ThiS family 15 92 1.6E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CP478_RS04735 2bfc320f3147eb90114fa0e32adf815b 92 Gene3D G3DSA:3.10.20.30 13 92 4.3E-22 T 28-03-2018 IPR012675 Beta-grasp domain CP478_RS04735 2bfc320f3147eb90114fa0e32adf815b 92 SUPERFAMILY SSF54285 12 90 7.48E-14 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CP478_RS04680 60d0dd608e6743c99011acedf8bcad92 157 SUPERFAMILY SSF55961 10 148 1.7E-21 T 28-03-2018 CP478_RS04680 60d0dd608e6743c99011acedf8bcad92 157 Gene3D G3DSA:3.30.530.20 5 154 9.2E-17 T 28-03-2018 IPR023393 START-like domain CP478_RS04680 60d0dd608e6743c99011acedf8bcad92 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 147 5.9E-12 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CP478_RS20255 cf1402982f3a133aeb305bd0dad25f85 336 Pfam PF13810 Domain of unknown function (DUF4185) 14 325 7.9E-50 T 28-03-2018 IPR025442 Domain of unknown function DUF4185 CP478_RS14850 5d07d663f25e85232ce60e6d963bba83 148 Pfam PF11298 Protein of unknown function (DUF3099) 33 104 6.3E-28 T 28-03-2018 IPR021449 Protein of unknown function DUF3099 CP478_RS08005 3d2725b78bf9231cf1dc71e367389eb1 268 SUPERFAMILY SSF46785 41 231 1.79E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08005 3d2725b78bf9231cf1dc71e367389eb1 268 Gene3D G3DSA:1.10.10.10 30 190 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS08005 3d2725b78bf9231cf1dc71e367389eb1 268 Pfam PF13412 Winged helix-turn-helix DNA-binding 43 84 1.3E-8 T 28-03-2018 CP478_RS19685 e1699ce2505b2b1453e07fda98e22778 158 Pfam PF11377 Protein of unknown function (DUF3180) 9 146 5.4E-39 T 28-03-2018 IPR021517 Protein of unknown function DUF3180 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 15 426 36.59 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 Pfam PF01566 Natural resistance-associated macrophage protein 52 400 1.5E-113 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 33 394 5.6E-85 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 PRINTS PR00447 Natural resistance-associated macrophage protein signature 139 158 4.4E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 PRINTS PR00447 Natural resistance-associated macrophage protein signature 165 186 4.4E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 PRINTS PR00447 Natural resistance-associated macrophage protein signature 214 237 4.4E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 PRINTS PR00447 Natural resistance-associated macrophage protein signature 316 335 4.4E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS05045 3c3c5f93c3ed38ef04b644e6b681b8e9 428 PRINTS PR00447 Natural resistance-associated macrophage protein signature 111 137 4.4E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CP478_RS18300 9c31743b5f3931515037440e050e1ef3 243 Gene3D G3DSA:3.40.50.150 7 226 9.1E-34 T 28-03-2018 CP478_RS18300 9c31743b5f3931515037440e050e1ef3 243 Pfam PF08241 Methyltransferase domain 43 131 1.2E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CP478_RS18300 9c31743b5f3931515037440e050e1ef3 243 SUPERFAMILY SSF53335 18 195 2.66E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS18580 04c8733e10ee8e621c60d1c5d28715c3 204 Gene3D G3DSA:3.20.20.70 1 186 3.7E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS11430 516a29a5a3e451665fa403ad1dacc233 550 SMART SM00507 399 450 2.1E-7 T 28-03-2018 IPR003615 HNH nuclease CP478_RS11430 516a29a5a3e451665fa403ad1dacc233 550 Pfam PF02720 Domain of unknown function (DUF222) 66 408 7.3E-55 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CP478_RS11430 516a29a5a3e451665fa403ad1dacc233 550 Gene3D G3DSA:3.40.1800.10 391 458 3.0E-6 T 28-03-2018 CP478_RS19835 7c01bb476f1d527593520dc1f3457b81 291 Gene3D G3DSA:2.60.120.620 2 230 3.1E-36 T 28-03-2018 CP478_RS19835 7c01bb476f1d527593520dc1f3457b81 291 SUPERFAMILY SSF51197 12 256 2.95E-51 T 28-03-2018 CP478_RS19835 7c01bb476f1d527593520dc1f3457b81 291 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 15 213 9.4E-38 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CP478_RS09630 5ef421e2ddc22e9b8c6cbe460eccdcad 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 84 2.3E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CP478_RS13490 17bcbaa84bbfcdfa5462b82737ef44c8 167 Pfam PF17174 Domain of unknown function (DUF5130) 26 161 1.2E-64 T 28-03-2018 IPR033437 Protein of unknown function DUF5130 CP478_RS09785 70351707aaf362186040b9e0405fb934 406 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 14 372 7.1E-113 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS09785 70351707aaf362186040b9e0405fb934 406 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 201 292 1.7E-23 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CP478_RS01225 891d0cf802498e96428fce89b4289810 421 Pfam PF11271 Protein of unknown function (DUF3068) 6 336 3.2E-96 T 28-03-2018 IPR021424 Porin PorA CP478_RS12765 88b18a60cad41256e3fb93f2785bc73f 413 SUPERFAMILY SSF140459 8 84 2.46E-23 T 28-03-2018 CP478_RS12765 88b18a60cad41256e3fb93f2785bc73f 413 Pfam PF00934 PE family 1 93 1.4E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS15350 7e208d71e581d9a837565d5b45c21d93 121 SUPERFAMILY SSF55729 33 112 1.03E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CP478_RS15350 7e208d71e581d9a837565d5b45c21d93 121 Gene3D G3DSA:3.40.630.30 4 119 2.0E-8 T 28-03-2018 CP478_RS10325 1e484515cac128ebcd5d5c15fa0d6259 303 SUPERFAMILY SSF53335 22 286 4.37E-65 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS10325 1e484515cac128ebcd5d5c15fa0d6259 303 Gene3D G3DSA:3.40.50.150 10 285 3.9E-48 T 28-03-2018 CP478_RS10325 1e484515cac128ebcd5d5c15fa0d6259 303 Pfam PF04072 Leucine carboxyl methyltransferase 26 201 3.9E-56 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CP478_RS10325 1e484515cac128ebcd5d5c15fa0d6259 303 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 24 279 1.5E-86 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CP478_RS21360 b24bee17726f85657fbf54cb590a5f22 802 Gene3D G3DSA:2.60.40.10 37 238 2.4E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CP478_RS13465 a145c9a71cd44d54f788d2593284b914 394 Gene3D G3DSA:3.40.710.10 1 394 4.8E-79 T 28-03-2018 CP478_RS13465 a145c9a71cd44d54f788d2593284b914 394 SUPERFAMILY SSF56601 11 384 3.22E-70 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CP478_RS13465 a145c9a71cd44d54f788d2593284b914 394 Pfam PF00144 Beta-lactamase 29 378 2.9E-72 T 28-03-2018 IPR001466 Beta-lactamase-related CP478_RS04220 b9e46d379c79cddca4f1ab968f213df6 259 Pfam PF04250 Protein of unknown function (DUF429) 5 220 9.8E-32 T 28-03-2018 IPR007362 Protein of unknown function DUF429 CP478_RS04220 b9e46d379c79cddca4f1ab968f213df6 259 PIRSF PIRSF018008 1 259 1.0E-109 T 28-03-2018 IPR008306 Uncharacterised conserved protein UCP018008 CP478_RS14480 1cd16942aeca1ee4193630cfd6772583 78 Pfam PF11455 Protein of unknown function (DUF3018) 13 76 9.7E-25 T 28-03-2018 IPR021558 Protein of unknown function DUF3018 CP478_RS00320 f715a62041d63a250a2ba15486221b43 230 Pfam PF14487 Domain of unknown function (DUF4433) 29 230 7.5E-51 T 28-03-2018 IPR029494 Domain of unknown function DUF4433 CP478_RS10755 75230ad2e7ada9381ca8c77a8de52286 135 Pfam PF05991 YacP-like NYN domain 4 125 8.5E-10 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CP478_RS04495 476c958c110b0fe96283e413e01329c9 96 Pfam PF07282 Putative transposase DNA-binding domain 4 44 3.6E-9 T 28-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CP478_RS10900 8b23a9a0ec07b8888b1e31d8b89ddc15 440 Pfam PF13520 Amino acid permease 18 399 8.9E-46 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS10900 8b23a9a0ec07b8888b1e31d8b89ddc15 440 PIRSF PIRSF006060 8 420 1.5E-73 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS14840 890b7bbaca954f699957d266325dcdf2 324 Pfam PF03631 Virulence factor BrkB 26 283 5.1E-45 T 28-03-2018 IPR017039 Virulence factor BrkB CP478_RS14840 890b7bbaca954f699957d266325dcdf2 324 PIRSF PIRSF035875 1 304 8.9E-65 T 28-03-2018 IPR017039 Virulence factor BrkB CP478_RS08790 fe5a5982449674e947c8233ae5a27ae1 360 Pfam PF01699 Sodium/calcium exchanger protein 216 358 4.3E-14 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CP478_RS08790 fe5a5982449674e947c8233ae5a27ae1 360 Pfam PF01699 Sodium/calcium exchanger protein 33 183 2.2E-12 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CP478_RS14120 054831ade2e874bf6d957ca6c97cbe52 154 PIRSF PIRSF021591 1 154 6.1E-71 T 28-03-2018 IPR016793 Uncharacterised conserved protein UCP021591 CP478_RS16265 8e67da4c30d70659508f3ae34eb5d42d 84 SUPERFAMILY SSF101473 8 77 9.94E-10 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CP478_RS03665 23aa8e1213730183a7c9d9c696f06739 165 SUPERFAMILY SSF46785 19 115 2.57E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS03665 23aa8e1213730183a7c9d9c696f06739 165 Gene3D G3DSA:1.10.10.10 14 151 1.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00475 5f158e2bbad086537d053e5314aa5640 220 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 17 195 7.0E-58 T 28-03-2018 CP478_RS05270 311a445b9212de341cf2cfd508dc73fe 139 Gene3D G3DSA:1.10.287.1060 26 123 4.2E-7 T 28-03-2018 CP478_RS05035 74eb74dc345a9491ea01c949da014141 550 Pfam PF01385 Probable transposase 271 394 1.2E-29 T 28-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CP478_RS06040 9bf039c9957b4d8b2668a10f631d5d17 233 Pfam PF14030 Protein of unknown function (DUF4245) 34 224 7.4E-53 T 28-03-2018 IPR025339 Protein of unknown function DUF4245 CP478_RS04010 a0c7af9b8eb5f804a29c066444c06df8 268 Pfam PF10774 Domain of unknown function (DUF4226) 6 108 3.6E-26 T 28-03-2018 IPR019710 Protein of unknown function DUF4226 CP478_RS09155 6721f74dfd0bb529a3b547c3bcbaf588 234 Gene3D G3DSA:3.40.30.10 42 227 1.3E-16 T 28-03-2018 CP478_RS09155 6721f74dfd0bb529a3b547c3bcbaf588 234 Pfam PF00578 AhpC/TSA family 51 205 1.6E-7 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CP478_RS09155 6721f74dfd0bb529a3b547c3bcbaf588 234 SUPERFAMILY SSF52833 182 223 4.8E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS09155 6721f74dfd0bb529a3b547c3bcbaf588 234 SUPERFAMILY SSF52833 47 146 4.8E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CP478_RS02350 da593fcc19ebc259498710f4b61682b4 487 SUPERFAMILY SSF140459 6 173 2.88E-56 T 28-03-2018 CP478_RS02350 da593fcc19ebc259498710f4b61682b4 487 Pfam PF01469 Pentapeptide repeats (8 copies) 218 256 2.3E-9 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS02350 da593fcc19ebc259498710f4b61682b4 487 Pfam PF01469 Pentapeptide repeats (8 copies) 261 299 1.9E-8 T 28-03-2018 IPR002989 Mycobacterial pentapeptide repeat CP478_RS02350 da593fcc19ebc259498710f4b61682b4 487 Pfam PF00823 PPE family 8 164 8.5E-56 T 28-03-2018 IPR000030 PPE family CP478_RS02350 da593fcc19ebc259498710f4b61682b4 487 Gene3D G3DSA:1.10.287.850 26 110 2.4E-5 T 28-03-2018 CP478_RS13705 8156cc50e2d32ee61de3418a7ed98baf 273 Pfam PF05423 Mycobacterium membrane protein 187 262 2.5E-5 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS07885 914f3a8c71d2180bb6ebb018e578d1b4 77 Pfam PF03840 Preprotein translocase SecG subunit 5 72 2.3E-14 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CP478_RS07885 914f3a8c71d2180bb6ebb018e578d1b4 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 4.4E-18 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CP478_RS20550 567a146898d83785e34cb8ac679f68cd 159 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 47 158 4.6E-37 T 28-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 CP478_RS11370 8b6c3c834c9e19fe292dbfdab0e3a38f 201 Pfam PF13276 HTH-like domain 79 113 5.8E-7 T 28-03-2018 IPR025948 HTH-like domain CP478_RS19740 ea5ed0af3354a8ac3bff25aaf4eaa5c9 103 Gene3D G3DSA:1.10.287.850 1 94 0.001 T 28-03-2018 CP478_RS19740 ea5ed0af3354a8ac3bff25aaf4eaa5c9 103 ProDom PD020336 ML0406 MB3895 RV3615C/MT3717 MB3645C 1 102 2.0E-54 T 28-03-2018 CP478_RS19740 ea5ed0af3354a8ac3bff25aaf4eaa5c9 103 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 100 1.4E-30 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CP478_RS00260 426716992f8cf5087fd0ef88029140fc 180 Pfam PF03551 Transcriptional regulator PadR-like family 6 81 3.5E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CP478_RS00260 426716992f8cf5087fd0ef88029140fc 180 Gene3D G3DSA:1.10.10.10 1 90 2.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00260 426716992f8cf5087fd0ef88029140fc 180 SUPERFAMILY SSF46785 2 170 1.25E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS00920 3bca5e5f8f621d2b761b19a3c09b7210 265 Pfam PF02405 Permease MlaE 46 256 3.2E-56 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS14605 a588e2f0afdff5c1fbb933adff49ec9d 84 Gene3D G3DSA:1.10.10.10 2 77 1.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS02825 d51775e303ead59ad1362e2de4fafe77 529 Pfam PF05140 ResB-like family 8 500 3.0E-137 T 28-03-2018 IPR007816 ResB-like domain CP478_RS12165 a690e65b16ffb132b228ffc94663c08c 255 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 5 222 1.7E-42 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CP478_RS21140 46ee5f033d08765031865b766ccc8efd 183 Gene3D G3DSA:3.30.1310.10 42 135 5.7E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CP478_RS14770 6d04f2c9a045f2b0df57b8c24be5f7f0 223 PIRSF PIRSF010219 1 213 2.0E-85 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CP478_RS14770 6d04f2c9a045f2b0df57b8c24be5f7f0 223 Pfam PF11361 Protein of unknown function (DUF3159) 16 199 5.3E-66 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CP478_RS12200 6dda09a5a9baea4288bf5de3ee9f7f91 414 Gene3D G3DSA:1.10.10.60 335 383 4.5E-8 T 28-03-2018 CP478_RS12200 6dda09a5a9baea4288bf5de3ee9f7f91 414 Pfam PF13556 PucR C-terminal helix-turn-helix domain 347 403 1.4E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS04565 8a03cc561cabd0d4dcd299b838636e19 342 PIRSF PIRSF012611 1 342 3.2E-136 T 28-03-2018 IPR016600 Uncharacterised conserved protein UCP012611 CP478_RS04565 8a03cc561cabd0d4dcd299b838636e19 342 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 200 335 8.0E-42 T 28-03-2018 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system CP478_RS04565 8a03cc561cabd0d4dcd299b838636e19 342 Gene3D G3DSA:1.10.10.10 116 341 8.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS06150 dec18ceacd32471671574b1e1873dceb 302 Pfam PF00561 alpha/beta hydrolase fold 50 150 3.7E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CP478_RS06150 dec18ceacd32471671574b1e1873dceb 302 SUPERFAMILY SSF53474 29 299 3.67E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS06150 dec18ceacd32471671574b1e1873dceb 302 Gene3D G3DSA:3.40.50.1820 27 300 3.1E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS10000 d355f185dd0c46702dbb49d142916871 131 Pfam PF01850 PIN domain 2 124 5.0E-17 T 28-03-2018 IPR002716 PIN domain CP478_RS10000 d355f185dd0c46702dbb49d142916871 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 131 15.213 T 28-03-2018 IPR022907 VapC family GO:0004540 CP478_RS10000 d355f185dd0c46702dbb49d142916871 131 SUPERFAMILY SSF88723 2 129 2.45E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS10000 d355f185dd0c46702dbb49d142916871 131 Gene3D G3DSA:3.40.50.1010 1 130 7.9E-20 T 28-03-2018 IPR029060 PIN domain-like CP478_RS14565 b1d39319d1eebefc2cdc01b607b675ca 130 ProDom PD032234 PHAGE PHIRV1 RV1583C/MT3573.2 PROBABLE RV2656C/MT2733 1 130 1.0E-66 T 28-03-2018 IPR024384 Protein of unknown function DUF2742 CP478_RS14565 b1d39319d1eebefc2cdc01b607b675ca 130 Pfam PF10888 Protein of unknown function (DUF2742) 34 130 1.3E-48 T 28-03-2018 IPR024384 Protein of unknown function DUF2742 CP478_RS10035 68c5547e2cb0f28fe750ccc3f8eae113 316 Gene3D G3DSA:3.30.2010.10 103 204 4.1E-13 T 28-03-2018 CP478_RS10035 68c5547e2cb0f28fe750ccc3f8eae113 316 Pfam PF01435 Peptidase family M48 144 205 9.5E-10 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CP478_RS18040 af2b6f7dd5ed504e3ac90880ccbde847 415 Gene3D G3DSA:3.10.180.10 59 322 0.003 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS18040 af2b6f7dd5ed504e3ac90880ccbde847 415 SMART SM01150 13 371 6.3E-169 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 CP478_RS18040 af2b6f7dd5ed504e3ac90880ccbde847 415 Pfam PF07063 Domain of unknown function (DUF1338) 11 371 8.2E-103 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 CP478_RS04435 e8dc9ecfa2c46e24d338ddf97f8aa8db 270 Pfam PF11209 Protein of unknown function (DUF2993) 27 255 1.2E-21 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 CP478_RS06660 df46026559f951ed49babcbfbb317075 224 Pfam PF04191 Phospholipid methyltransferase 111 203 7.1E-12 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CP478_RS14255 1ece4a78245c146c636e76391f0c9df0 95 Gene3D G3DSA:1.10.1220.10 2 38 2.1E-11 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS14255 1ece4a78245c146c636e76391f0c9df0 95 SUPERFAMILY SSF47598 2 40 9.64E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CP478_RS11130 ec4f5e4988423e9e007c55330c16ff41 300 Gene3D G3DSA:1.10.3720.10 59 292 3.3E-45 T 28-03-2018 CP478_RS11130 ec4f5e4988423e9e007c55330c16ff41 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 289 2.8E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS11130 ec4f5e4988423e9e007c55330c16ff41 300 Gene3D G3DSA:1.20.58.370 1 43 1.3E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CP478_RS11130 ec4f5e4988423e9e007c55330c16ff41 300 SUPERFAMILY SSF161098 53 283 5.76E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CP478_RS06620 f2754cffb7d176f2399cfdd85186b672 324 SUPERFAMILY SSF53448 45 285 4.5E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS06620 f2754cffb7d176f2399cfdd85186b672 324 Pfam PF00535 Glycosyl transferase family 2 46 156 2.1E-10 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS06620 f2754cffb7d176f2399cfdd85186b672 324 Gene3D G3DSA:3.90.550.10 35 283 4.3E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS19070 c91b34bc801782af24aca760c8bf5f61 149 Pfam PF07681 DoxX 11 89 2.4E-14 T 28-03-2018 IPR032808 DoxX family CP478_RS00075 d5ff908872679e9bb3530064b117c6b4 262 Pfam PF05949 Bacterial protein of unknown function (DUF881) 105 255 2.3E-37 T 28-03-2018 IPR010273 Protein of unknown function DUF881 CP478_RS02525 df53b313cf0a562778c4aebc74e49ff3 456 Pfam PF04286 Protein of unknown function (DUF445) 92 454 6.6E-105 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CP478_RS02525 df53b313cf0a562778c4aebc74e49ff3 456 Gene3D G3DSA:1.25.10.10 106 417 2.3E-4 T 28-03-2018 IPR011989 Armadillo-like helical CP478_RS07520 e08fbff21cff04a298d764240f8b5832 489 SUPERFAMILY SSF55856 29 80 4.32E-11 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CP478_RS07520 e08fbff21cff04a298d764240f8b5832 489 Pfam PF00487 Fatty acid desaturase 172 403 1.4E-13 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CP478_RS07520 e08fbff21cff04a298d764240f8b5832 489 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 28 88 3.8E-17 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CP478_RS07520 e08fbff21cff04a298d764240f8b5832 489 Gene3D G3DSA:3.10.120.10 25 87 4.0E-8 T 28-03-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CP478_RS07905 02ad2517df2fa57ca353ade320de43ff 161 Gene3D G3DSA:3.30.530.20 9 161 1.4E-18 T 28-03-2018 IPR023393 START-like domain CP478_RS07905 02ad2517df2fa57ca353ade320de43ff 161 SUPERFAMILY SSF55961 10 157 1.57E-14 T 28-03-2018 CP478_RS03230 c2520c9720d5a8cc89fab02020badb5e 316 Pfam PF07485 Domain of Unknown Function (DUF1259) 52 171 2.6E-43 T 28-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CP478_RS03230 c2520c9720d5a8cc89fab02020badb5e 316 Pfam PF07485 Domain of Unknown Function (DUF1259) 194 311 7.9E-46 T 28-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CP478_RS03230 c2520c9720d5a8cc89fab02020badb5e 316 Gene3D G3DSA:3.40.190.10 1 304 1.1E-6 T 28-03-2018 CP478_RS02800 de249939115aad0165ec3ffa92186b58 131 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 107 1.5E-22 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CP478_RS02800 de249939115aad0165ec3ffa92186b58 131 Gene3D G3DSA:2.30.110.10 11 120 1.1E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CP478_RS19305 d2cd69a10844c6d7b1d31a87c4d612b7 375 Gene3D G3DSA:2.60.120.600 211 348 1.4E-11 T 28-03-2018 IPR010621 Domain of unknown function DUF1214 CP478_RS19305 d2cd69a10844c6d7b1d31a87c4d612b7 375 Gene3D G3DSA:2.60.120.600 49 148 5.9E-5 T 28-03-2018 IPR010621 Domain of unknown function DUF1214 CP478_RS16250 a2a2614825e2ca14287aa9304ccb723c 237 Pfam PF07510 Protein of unknown function (DUF1524) 90 216 3.2E-12 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CP478_RS08645 d49b5fc990fc071b7024eb139e78ef87 104 Gene3D G3DSA:1.10.8.10 19 41 3.0E-4 T 28-03-2018 CP478_RS20200 919a730a0e2971c518c1a5921bc963fb 74 Gene3D G3DSA:1.10.1220.10 1 42 3.3E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS01140 3a5f813220eb517e91a0e7127a7cd235 492 Gene3D G3DSA:3.40.50.300 44 466 4.8E-5 T 28-03-2018 CP478_RS04480 3b9b4a4b1b202e5d90385e09c7d89f7d 351 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 59 294 7.3E-58 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CP478_RS08945 50ad6c327f3935d33e4dae1345155e3e 556 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 114 265 5.8E-8 T 28-03-2018 CP478_RS19295 32f237b53223ff36d37f53d4197deec8 384 SUPERFAMILY SSF52540 185 357 2.83E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19295 32f237b53223ff36d37f53d4197deec8 384 SUPERFAMILY SSF52540 89 137 2.83E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS19295 32f237b53223ff36d37f53d4197deec8 384 Pfam PF13469 Sulfotransferase family 93 341 1.4E-64 T 28-03-2018 CP478_RS19295 32f237b53223ff36d37f53d4197deec8 384 Gene3D G3DSA:3.40.50.300 57 369 1.7E-31 T 28-03-2018 CP478_RS19580 4ccaf35c7b2064f86e8aae565a99b1a7 162 SUPERFAMILY SSF141259 3 66 4.18E-15 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS19580 4ccaf35c7b2064f86e8aae565a99b1a7 162 SMART SM01058 2 112 1.8E-34 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS19580 4ccaf35c7b2064f86e8aae565a99b1a7 162 Pfam PF02559 CarD-like/TRCF domain 3 111 1.1E-19 T 28-03-2018 IPR003711 CarD-like/TRCF domain CP478_RS17870 ef5e68e7734adf34380cfb13d667423f 89 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 13 89 19.095 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS17870 ef5e68e7734adf34380cfb13d667423f 89 Pfam PF02467 Transcription factor WhiB 21 84 2.7E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS14340 3e44e6c7f833f7b9fcdca10eef915eef 146 Pfam PF07681 DoxX 24 106 5.9E-6 T 28-03-2018 IPR032808 DoxX family CP478_RS21055 ebbef114bc28aa848511ba81390bb469 94 Gene3D G3DSA:1.10.3470.10 13 94 0.0011 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CP478_RS14775 686eadba058e44ec37991ffe926b68ab 122 Gene3D G3DSA:2.40.50.140 36 122 2.7E-9 T 28-03-2018 CP478_RS14775 686eadba058e44ec37991ffe926b68ab 122 PIRSF PIRSF006910 1 122 4.0E-68 T 28-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted CP478_RS07675 21583aee0235a5a4314745e55293bcaf 200 Pfam PF07947 YhhN family 3 183 2.9E-47 T 28-03-2018 IPR012506 YhhN-like GO:0016021 CP478_RS16935 875dd7414f6c9b7ce9b555da6270337d 158 Pfam PF01638 HxlR-like helix-turn-helix 21 108 4.3E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CP478_RS16935 875dd7414f6c9b7ce9b555da6270337d 158 Gene3D G3DSA:1.10.10.10 6 158 1.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS16935 875dd7414f6c9b7ce9b555da6270337d 158 SUPERFAMILY SSF46785 12 146 1.01E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS17420 5bbb74f94640c89104fb8105b8f05a53 114 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 12 103 4.6E-23 T 28-03-2018 IPR009241 Toxin HigB-like CP478_RS09320 b6e26cc2c441d0082afc72cabc2fc66d 318 SUPERFAMILY SSF52540 64 316 1.28E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CP478_RS09320 b6e26cc2c441d0082afc72cabc2fc66d 318 Pfam PF13614 AAA domain 65 241 8.9E-61 T 28-03-2018 IPR025669 AAA domain CP478_RS09320 b6e26cc2c441d0082afc72cabc2fc66d 318 Gene3D G3DSA:3.40.50.300 63 317 1.4E-59 T 28-03-2018 CP478_RS01030 d9fd42932e243c0fe7ccd5447c23daef 143 Pfam PF03779 SPW repeat 88 135 8.0E-18 T 28-03-2018 IPR005530 SPW repeat CP478_RS01030 d9fd42932e243c0fe7ccd5447c23daef 143 Pfam PF03779 SPW repeat 35 80 8.1E-16 T 28-03-2018 IPR005530 SPW repeat CP478_RS03290 2fc7a4004e2bbbde0abebe982416c06d 855 Gene3D G3DSA:3.10.450.50 320 468 1.2E-9 T 28-03-2018 CP478_RS03290 2fc7a4004e2bbbde0abebe982416c06d 855 SUPERFAMILY SSF103642 448 468 2.13E-7 T 28-03-2018 CP478_RS03290 2fc7a4004e2bbbde0abebe982416c06d 855 Pfam PF02810 SEC-C motif 449 465 2.4E-9 T 28-03-2018 IPR004027 SEC-C motif CP478_RS03615 421ee66efdcf5fa217d53ecc72f6f236 637 Pfam PF17048 Neutral/alkaline non-lysosomal ceramidase, C-terminal 485 636 5.7E-37 T 28-03-2018 IPR031331 Neutral/alkaline non-lysosomal ceramidase, C-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119 CP478_RS03615 421ee66efdcf5fa217d53ecc72f6f236 637 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 4 482 5.3E-147 T 28-03-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 CP478_RS10675 137f8365e628069d35b6e2adebca4fb5 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 42 1.0E-7 T 28-03-2018 CP478_RS10675 137f8365e628069d35b6e2adebca4fb5 90 Gene3D G3DSA:3.40.1620.10 2 90 1.6E-11 T 28-03-2018 CP478_RS10700 8e087053c767a8834005700d6b3d3f28 271 Pfam PF02405 Permease MlaE 54 258 1.0E-49 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS07815 1a0234a1a370fc88e35f81fd168b6f7f 422 Pfam PF13556 PucR C-terminal helix-turn-helix domain 351 408 1.3E-16 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CP478_RS18500 3cdcf0090b0b3d63b6ec09a5aafdd043 296 Gene3D G3DSA:3.40.1180.10 23 249 4.5E-6 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CP478_RS13115 bdd96d7a56adf53f157dd9c82f77df68 251 Pfam PF14032 PknH-like extracellular domain 42 246 1.2E-40 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS17330 0d69d5ce8a83568b4385bccfe5735181 319 Pfam PF13559 Domain of unknown function (DUF4129) 237 307 9.6E-11 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CP478_RS04785 163fc077b08be075d33c5b92b8a9cdba 262 Pfam PF11228 Protein of unknown function (DUF3027) 45 234 1.2E-80 T 28-03-2018 IPR021391 Protein of unknown function DUF3027 CP478_RS19115 078bced39e2ba187d43a21192e696b67 384 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 305 1.8E-81 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS19115 078bced39e2ba187d43a21192e696b67 384 Pfam PF02470 MlaD protein 41 120 9.7E-12 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS13525 67bc14ce7e7c0c41270e989652f23f95 217 PIRSF PIRSF012637 1 217 5.3E-100 T 28-03-2018 IPR016601 Uncharacterised conserved protein UCP012637 CP478_RS04350 d36176e7a386a5e7cf7b8c794a005e1a 115 SUPERFAMILY SSF54593 1 113 4.37E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS04350 d36176e7a386a5e7cf7b8c794a005e1a 115 Gene3D G3DSA:3.10.180.10 1 115 2.8E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CP478_RS08225 b5798189c69ee4d62f728badca08a8c6 342 Pfam PF00535 Glycosyl transferase family 2 4 198 8.1E-40 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS08225 b5798189c69ee4d62f728badca08a8c6 342 SUPERFAMILY SSF53448 1 189 3.44E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08225 b5798189c69ee4d62f728badca08a8c6 342 Gene3D G3DSA:3.90.550.10 1 265 2.3E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS11505 5bf041d72ee88bef5d13a17f998d1492 207 PIRSF PIRSF021573 1 207 2.6E-99 T 28-03-2018 IPR016792 Uncharacterised conserved protein UCP021573 CP478_RS12535 8f03f2dcf913bbe83fa96500755160cd 161 Pfam PF09335 SNARE associated Golgi protein 4 69 4.4E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein CP478_RS02635 d0b9d7a63db54cfc9d50f3d4132f6124 329 ProDom PD133063 RV0493C/MT0513 MB0504C BLSR 14 329 4.0E-172 T 28-03-2018 CP478_RS04530 5e3f0d6f1d7533e29e4e8ebf6b385a67 137 SUPERFAMILY SSF140459 8 84 1.78E-22 T 28-03-2018 CP478_RS04530 5e3f0d6f1d7533e29e4e8ebf6b385a67 137 Pfam PF00934 PE family 2 92 1.4E-29 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS19830 60cd4a2f97ba67017a341aaf050721ef 114 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 3 106 9.4E-27 T 28-03-2018 IPR019277 Protein of unknown function DUF2304 CP478_RS19955 393a5ebad3eb2d0d2499e7856f6b5f80 68 Pfam PF14029 Protein of unknown function (DUF4244) 13 65 5.6E-23 T 28-03-2018 IPR025338 Protein of unknown function DUF4244 CP478_RS14115 990d2a2133d09b4c0870c2234237d1e4 293 SUPERFAMILY SSF55486 137 213 8.88E-6 T 28-03-2018 CP478_RS14115 990d2a2133d09b4c0870c2234237d1e4 293 Pfam PF04228 Putative neutral zinc metallopeptidase 14 287 7.6E-75 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CP478_RS17985 61254b2a6920e9542d15557ecdaea0d8 177 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 112 162 3.6E-14 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit CP478_RS16940 4038df4537bf3d5fdef9bc1d487b6329 379 Gene3D G3DSA:3.20.20.80 42 359 8.9E-30 T 28-03-2018 CP478_RS16940 4038df4537bf3d5fdef9bc1d487b6329 379 SUPERFAMILY SSF51445 45 357 2.39E-59 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CP478_RS08320 3454adddd5c0357a275acd2255ae6c9a 254 Pfam PF11139 Sap, sulfolipid-1-addressing protein 5 251 5.3E-64 T 28-03-2018 IPR021315 Glycolipid exporter Gap/Sap CP478_RS17595 b7eb4797a664f7a9374e4f32e79124fd 186 Pfam PF05423 Mycobacterium membrane protein 91 169 2.4E-5 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS15125 077e9fd6c2347f10661594b51fe23fed 364 SUPERFAMILY SSF116734 6 165 9.97E-25 T 28-03-2018 CP478_RS15125 077e9fd6c2347f10661594b51fe23fed 364 Gene3D G3DSA:3.90.220.20 4 157 6.8E-12 T 28-03-2018 CP478_RS15125 077e9fd6c2347f10661594b51fe23fed 364 Pfam PF01420 Type I restriction modification DNA specificity domain 5 160 1.3E-7 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CP478_RS15125 077e9fd6c2347f10661594b51fe23fed 364 Gene3D G3DSA:3.90.220.20 193 311 0.0089 T 28-03-2018 CP478_RS01600 7867f612ed64c315fcf605aacb558213 591 SUPERFAMILY SSF140459 8 84 4.45E-23 T 28-03-2018 CP478_RS01600 7867f612ed64c315fcf605aacb558213 591 Pfam PF00934 PE family 2 93 5.4E-31 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CP478_RS03530 4524c817bbbe8e10977597ba7b6f0684 501 Pfam PF03055 Retinal pigment epithelial membrane protein 19 499 2.2E-101 T 28-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CP478_RS21395 e60ec36f03f8612e999e3f8f2a797d07 244 Gene3D G3DSA:3.40.630.30 3 223 1.7E-5 T 28-03-2018 CP478_RS01040 b2780861c6f503efd9cea59685ca7b08 96 Pfam PF02583 Metal-sensitive transcriptional repressor 11 91 6.2E-31 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CP478_RS08330 406b774650a7e5d0fa199a79f91a0d98 89 Gene3D G3DSA:3.90.1150.10 22 86 4.0E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CP478_RS08330 406b774650a7e5d0fa199a79f91a0d98 89 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 34 79 1.5E-5 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CP478_RS08335 5f72e91ace67fb617e80cef32995f3c4 346 SUPERFAMILY SSF53448 1 219 8.53E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS08335 5f72e91ace67fb617e80cef32995f3c4 346 Pfam PF00535 Glycosyl transferase family 2 2 131 3.3E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CP478_RS08335 5f72e91ace67fb617e80cef32995f3c4 346 Gene3D G3DSA:3.90.550.10 1 242 8.1E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CP478_RS10990 9723a2bea03ce9a47817b593c1e7e208 196 Pfam PF02371 Transposase IS116/IS110/IS902 family 57 141 5.1E-18 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CP478_RS19225 fe4e529442773e84303297ac1b5f0a38 279 Gene3D G3DSA:3.40.960.10 177 270 7.5E-8 T 28-03-2018 CP478_RS20670 2f1fc5e91a4cffcdfea284e4ef0cb2bb 280 Pfam PF01061 ABC-2 type transporter 33 241 1.6E-25 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CP478_RS07060 6aba6f434bfd5caca235d766717e0e7d 111 Pfam PF05305 Protein of unknown function (DUF732) 17 108 1.8E-23 T 28-03-2018 IPR007969 Domain of unknown function DUF732 CP478_RS02760 caa49385b4be724ba80067ee4c3eadd6 158 SUPERFAMILY SSF52091 37 136 2.35E-12 T 28-03-2018 IPR002645 STAS domain CP478_RS02760 caa49385b4be724ba80067ee4c3eadd6 158 Pfam PF01740 STAS domain 35 135 2.9E-12 T 28-03-2018 IPR002645 STAS domain CP478_RS02760 caa49385b4be724ba80067ee4c3eadd6 158 Gene3D G3DSA:3.30.750.24 26 141 1.1E-13 T 28-03-2018 IPR002645 STAS domain CP478_RS02645 b9364fd6f579bf03cfce5aa02e5d13e8 296 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 46 291 3.0E-143 T 28-03-2018 CP478_RS16665 2224742a28ee8c85b45017d51fba8ec5 124 Pfam PF11829 Protein of unknown function (DUF3349) 10 105 8.7E-29 T 28-03-2018 IPR021784 Protein of unknown function DUF3349 CP478_RS17645 78b5215d246fadfa9489d23c9661b381 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.597 T 28-03-2018 IPR003482 Transcription factor WhiB CP478_RS17645 78b5215d246fadfa9489d23c9661b381 84 Pfam PF02467 Transcription factor WhiB 3 71 8.7E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CP478_RS15005 8c4a85be3ce54f75f4121da0ec6fb191 68 Pfam PF11248 Protein of unknown function (DUF3046) 5 65 2.4E-28 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 CP478_RS03175 dfa2a95ed00eacc23dd53f488240f654 402 Pfam PF02470 MlaD protein 68 139 6.2E-11 T 28-03-2018 IPR003399 Mce/MlaD CP478_RS03175 dfa2a95ed00eacc23dd53f488240f654 402 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 36 325 7.2E-90 T 28-03-2018 IPR005693 Virulence factor Mce protein CP478_RS13945 1ee276ee9dd31eeb968b6ddd16d54abe 220 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 42 194 8.6E-39 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CP478_RS10880 fad02b41f2ff070e2de5d5a36516d9c1 255 Gene3D G3DSA:1.20.120.520 58 228 3.1E-18 T 28-03-2018 CP478_RS10880 fad02b41f2ff070e2de5d5a36516d9c1 255 Pfam PF01814 Hemerythrin HHE cation binding domain 69 201 1.6E-13 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CP478_RS10880 fad02b41f2ff070e2de5d5a36516d9c1 255 Pfam PF01814 Hemerythrin HHE cation binding domain 139 223 1.3E-7 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CP478_RS04955 860cbf9797a5934ea0d7cdf7e869b014 59 Pfam PF14013 MT0933-like antitoxin protein 4 49 2.3E-16 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CP478_RS16495 ecd42869ed56aa8b398d699843c3c456 209 Pfam PF14032 PknH-like extracellular domain 43 194 1.5E-11 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS14800 2bf4985892de7f056b07023b1118b7d1 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 1.6E-44 T 28-03-2018 IPR025242 Protein of unknown function DUF4193 CP478_RS01115 eedb431c4faa5ed10dda887d0ecb3898 367 Pfam PF01594 AI-2E family transporter 22 346 2.0E-80 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CP478_RS12440 8a87522fe614eb59635ead24dadcbeda 171 Pfam PF05481 Mycobacterium 19 kDa lipoprotein antigen 44 170 1.0E-12 T 28-03-2018 IPR008691 19kDa lipoprotein antigen GO:0016020 CP478_RS11390 847f7a1583b27aa030cf8740d6e1cab8 244 Pfam PF14230 Domain of unknown function (DUF4333) 154 236 2.3E-26 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CP478_RS12395 9f432f78f918749da4cad6a60ceebed0 552 Pfam PF01384 Phosphate transporter family 84 541 7.9E-112 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CP478_RS08855 3fbd06ddaa7f80b558b83d639e91cda6 484 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 160 459 1.1E-66 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CP478_RS08855 3fbd06ddaa7f80b558b83d639e91cda6 484 Gene3D G3DSA:3.40.50.1010 261 406 0.018 T 28-03-2018 IPR029060 PIN domain-like CP478_RS07305 ba26a389e89f88cbc0ef473720f9b25e 218 Pfam PF09438 Domain of unknown function (DUF2017) 32 215 5.4E-59 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 CP478_RS12675 2a645cad2e0ad8bdaeda8649fbf626c9 282 Pfam PF02361 Cobalt transport protein 28 245 9.4E-50 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CP478_RS17345 1a894286dcbcf88843f68eb6bab3f12e 374 SUPERFAMILY SSF159245 25 265 1.44E-7 T 28-03-2018 CP478_RS00610 e59390d63108d7e061cb9ca417ec5287 685 Pfam PF01757 Acyltransferase family 34 385 3.7E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CP478_RS00610 e59390d63108d7e061cb9ca417ec5287 685 SUPERFAMILY SSF52266 468 680 1.19E-15 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CP478_RS00610 e59390d63108d7e061cb9ca417ec5287 685 Gene3D G3DSA:3.40.50.1110 449 682 2.1E-15 T 28-03-2018 CP478_RS03740 3c700290dea939a7b43e25e74343116b 62 TIGRFAM TIGR03969 mycofactocin: mycofactocin precursor 41 62 3.6E-14 T 28-03-2018 IPR023988 Mycofactocin CP478_RS12950 54c7595a77bc666d43621fa979c7a247 105 PIRSF PIRSF006909 1 103 2.8E-61 T 28-03-2018 IPR014447 Uncharacterised conserved protein UCP006909 CP478_RS12650 e706881322b31c4b2e6b709fbc32da65 476 Pfam PF13520 Amino acid permease 35 442 1.4E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS12650 e706881322b31c4b2e6b709fbc32da65 476 PIRSF PIRSF006060 21 475 2.4E-88 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CP478_RS10110 4383cea0e98d67e9f28b2610f0149fea 325 Pfam PF07174 Fibronectin-attachment protein (FAP) 1 297 5.3E-141 T 28-03-2018 IPR010801 Fibronectin-attachment GO:0005576|GO:0050840 CP478_RS01135 b3d700a9b1b8dff9ac869daabbfa885d 361 Gene3D G3DSA:1.20.120.430 66 246 0.0021 T 28-03-2018 CP478_RS12185 426b6779835a4e51c12edba4d069b1af 158 Pfam PF11253 Protein of unknown function (DUF3052) 29 152 1.8E-55 T 28-03-2018 IPR021412 Protein of unknown function DUF3052 CP478_RS09395 f8021dc3a2a96402c78393939d8945d8 494 Gene3D G3DSA:3.30.470.20 134 451 3.3E-21 T 28-03-2018 CP478_RS09395 f8021dc3a2a96402c78393939d8945d8 494 SUPERFAMILY SSF56059 127 353 1.94E-20 T 28-03-2018 CP478_RS10305 dd2e14c80308387e1a6afb8f6cbef8e9 72 Gene3D G3DSA:1.10.287.700 5 69 1.9E-4 T 28-03-2018 CP478_RS17965 b168f77df05348fc008c38f1f240fef0 272 Pfam PF04138 GtrA-like protein 76 206 2.4E-22 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CP478_RS00035 82add2eb24ef198ffa15dc7b14239693 304 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 187 302 4.0E-41 T 28-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane CP478_RS01960 2521269a5643ccc6661817cd6e249009 129 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 7 106 4.7E-22 T 28-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system CP478_RS16855 0bbcf71f1a5fa0f62414a72c383421f0 412 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 253 330 1.4E-4 T 28-03-2018 IPR018700 Protein of unknown function DUF2204 CP478_RS11950 9b5cad1660364c3efdd63db727c993e6 299 Pfam PF05423 Mycobacterium membrane protein 205 286 7.0E-7 T 28-03-2018 IPR008693 Transport accessory protein MmpS CP478_RS14245 59c97da1b3f548593a0dad68a2754543 133 Pfam PF03994 Domain of Unknown Function (DUF350) 78 132 6.7E-10 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CP478_RS14245 59c97da1b3f548593a0dad68a2754543 133 Pfam PF03994 Domain of Unknown Function (DUF350) 7 61 6.6E-11 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CP478_RS20700 c86e9e27da49da98002e1cb28ad294b9 121 Pfam PF04138 GtrA-like protein 2 118 1.1E-19 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CP478_RS08140 45465e88d1c7daf099ddf420d096b35b 288 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 2 278 4.0E-144 T 28-03-2018 CP478_RS02140 2b82a270503554d514a82e7461a89cc0 123 Pfam PF11255 Protein of unknown function (DUF3054) 10 112 5.4E-34 T 28-03-2018 IPR021414 Protein of unknown function DUF3054 CP478_RS10115 99741b46e8d1518380ee92efbc60fc28 101 Pfam PF04226 Transglycosylase associated protein 51 100 8.0E-12 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CP478_RS01855 3a3115438e16cdc5e1f73aa706a04325 328 TIGRFAM TIGR04255 sporadTIGR04255: TIGR04255 family protein 67 320 2.3E-48 T 28-03-2018 IPR026349 Conserved hypothetical protein CHP04255 CP478_RS05460 d7313bd3848e686a0b4ac3243b4b5e94 151 Gene3D G3DSA:3.40.50.150 38 151 9.4E-15 T 28-03-2018 CP478_RS05460 d7313bd3848e686a0b4ac3243b4b5e94 151 Pfam PF13649 Methyltransferase domain 79 150 5.0E-10 T 28-03-2018 CP478_RS05460 d7313bd3848e686a0b4ac3243b4b5e94 151 SUPERFAMILY SSF53335 56 150 6.27E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CP478_RS15040 80796f163c96a24d454496e490c17e89 270 Pfam PF04012 PspA/IM30 family 3 241 3.7E-63 T 28-03-2018 IPR007157 PspA/IM30 CP478_RS03145 7448e1b9cc06fb15c52811a2b3dce284 265 Pfam PF02405 Permease MlaE 47 256 4.2E-56 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CP478_RS17715 55a239e18948e3b3d424b599c3ac8d1e 427 Pfam PF00487 Fatty acid desaturase 69 339 4.2E-37 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CP478_RS17715 55a239e18948e3b3d424b599c3ac8d1e 427 Gene3D G3DSA:1.10.10.10 2 42 0.11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CP478_RS11955 beafc00e642ce3ebc4c53f32dc13ccb3 139 PIRSF PIRSF017385 1 139 6.7E-52 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CP478_RS11955 beafc00e642ce3ebc4c53f32dc13ccb3 139 Pfam PF12270 Cytochrome c oxidase subunit IV 1 137 1.3E-50 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CP478_RS03780 48d0ff6477b84fb553e5fe3854722259 57 Pfam PF01610 Transposase 5 56 3.1E-12 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CP478_RS08835 d04103d358dc44c319c33e9fe57afa74 146 Pfam PF05154 TM2 domain 72 126 2.7E-11 T 28-03-2018 IPR007829 TM2 domain CP478_RS11340 e009a22b93085b89e7361f4a400dfbea 187 Gene3D G3DSA:3.40.50.720 5 137 0.0011 T 28-03-2018 CP478_RS15650 32e2e4810cf2d0c82924c02876ff0bd5 82 Gene3D G3DSA:1.10.1220.10 2 32 8.7E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS09875 ed1e5c8f1ce6bd7d1c00a323fca7f098 300 Pfam PF04116 Fatty acid hydroxylase superfamily 94 227 4.1E-25 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CP478_RS12710 5e82f52bbb00454ffa77d4b2f0cc5225 128 SUPERFAMILY SSF53706 6 66 2.14E-5 T 28-03-2018 CP478_RS18830 b1fd8f08cf28f71ec30d2cea9da55def 103 Gene3D G3DSA:1.10.287.1060 8 103 1.1E-5 T 28-03-2018 CP478_RS02280 9469ae866636349914464b413fb6f229 302 Gene3D G3DSA:3.40.630.30 4 300 9.4E-8 T 28-03-2018 CP478_RS09495 c31cc02d04ab846ef547c47cf363be94 70 Pfam PF07704 Rv0623-like transcription factor 2 69 3.9E-17 T 28-03-2018 IPR011660 Antitoxin VapB-like CP478_RS00825 6a892283d491167be5d2b28f621f81ea 525 Gene3D G3DSA:3.40.50.1820 37 283 2.0E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CP478_RS00825 6a892283d491167be5d2b28f621f81ea 525 Pfam PF08237 PE-PPE domain 111 335 2.8E-68 T 28-03-2018 IPR013228 PE-PPE, C-terminal CP478_RS20240 649d42aa76098393233515cd6199c546 214 Pfam PF14032 PknH-like extracellular domain 30 210 2.0E-39 T 28-03-2018 IPR026954 PknH-like extracellular domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CP478_RS12260 d38049b49ce7adfa599cbef44fb5abad 151 Pfam PF01810 LysE type translocator 23 147 1.1E-7 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CP478_RS11795 21c6822413035a72c7b278144ffc27ed 134 Pfam PF11239 Protein of unknown function (DUF3040) 1 86 1.7E-28 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CP478_RS09695 58e67b6929eb2c84e0d0f81028ef277e 597 Pfam PF14362 Domain of unknown function (DUF4407) 35 318 1.0E-54 T 28-03-2018 IPR025519 Protein of unknown function DUF4407 CP478_RS14325 138923d38cccc2909752ccb45ecf0279 75 Gene3D G3DSA:3.20.20.70 1 35 5.5E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CP478_RS08265 e0b6052c5bde7d9caaf661e68d2457b9 599 Pfam PF09594 Glycosyltransferase family 87 201 431 4.8E-7 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CP478_RS01860 fb45f7c790500fbc8460efc2ebf4c1f7 217 Gene3D G3DSA:1.10.260.40 78 166 3.4E-4 T 28-03-2018 CP478_RS15425 bf0c7fffb3e33f18a550008618413cd4 302 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 5 295 8.2E-83 T 28-03-2018 IPR005510 Protein of unknown function DUF314 CP478_RS02290 9426f88e1815fb9f38aac10629b75547 102 Pfam PF11662 Protein of unknown function (DUF3263) 21 92 5.4E-36 T 28-03-2018 IPR021678 Protein of unknown function DUF3263 CP478_RS17445 596eb0a0f0891cee10eb933b8834f0c1 206 SMART SM00953 33 158 3.6E-5 T 28-03-2018 IPR014914 RES domain CP478_RS17445 596eb0a0f0891cee10eb933b8834f0c1 206 Pfam PF08808 RES domain 18 158 1.2E-15 T 28-03-2018 IPR014914 RES domain CP478_RS06625 63bb4a6e44ce465b257aaec0a84bcdbc 122 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 50 82 6.7E-10 T 28-03-2018 IPR019933 DivIVA domain CP478_RS00965 36ec9240f223b2c3b5e6c35c46581432 322 Pfam PF06271 RDD family 21 143 3.6E-16 T 28-03-2018 IPR010432 RDD CP478_RS02845 c2ca17aa89824d159bda63fc3f317f67 105 Pfam PF14012 Protein of unknown function (DUF4229) 17 85 2.6E-20 T 28-03-2018 IPR025323 Protein of unknown function DUF4229 CP478_RS02820 530fa2a2a9e4afa954fce760736d228b 259 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 236 7.5E-40 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CP478_RS01485 7a02f8c8fee7d2d2e904c34b7f1e1c4c 306 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 44 273 3.1E-48 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CP478_RS07185 3b7c17f19fe54eb526305a18b4e6c675 147 Pfam PF10739 Protein of unknown function (DUF2550) 11 139 4.5E-41 T 28-03-2018 IPR019675 Protein of unknown function DUF2550 CP478_RS15730 3c78a34bb49c8fd1b79bcb642508591e 287 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 220 1.8E-10 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CP478_RS00445 4a35606a748817e8045ad6807a320e0f 273 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 133 179 4.4E-10 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CP478_RS17505 71fd7329794870b698e6d12da2d1f345 299 Gene3D G3DSA:3.40.50.720 58 299 2.5E-14 T 28-03-2018 CP478_RS06055 46422430c9918d59e798cd8f38045ae5 106 Gene3D G3DSA:1.10.1220.10 32 73 1.8E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CP478_RS20380 a968d653b80639d78487ac78d1d3ef79 346 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 264 3.7E-64 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CP478_RS03225 22e97f39adbae18046ec26e37b3f304b 103 Gene3D G3DSA:3.10.450.40 37 94 3.6E-5 T 28-03-2018 CP478_RS18340 136dda472d0a125280f2716c378bb9d7 272 Pfam PF01610 Transposase 25 155 1.3E-19 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain