locus-tag	class	description
FPK02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPK02_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FPK02_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPK02_RS00090	COG0515	serine threonine protein kinase
FPK02_RS00115	COG1716	ATPase activity
FPK02_RS00185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPK02_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS00245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPK02_RS00245	COG0596	Alpha beta hydrolase
FPK02_RS00250	COG1260	myo-inositol-1-phosphate synthase
FPK02_RS00270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPK02_RS00335	COG0277	FAD linked oxidase domain protein
FPK02_RS00365	COG1309	transcriptional regulator
FPK02_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS00385	COG3344	reverse transcriptase
FPK02_RS00405	COG1228	amidohydrolase
FPK02_RS00425	COG1309	transcriptional regulator
FPK02_RS00455	COG3260	NADH ubiquinone oxidoreductase 20
FPK02_RS00465	COG0650	Formate hydrogenlyase subunit 4
FPK02_RS00475	COG0651	ATP synthesis coupled electron transport
FPK02_RS00480	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FPK02_RS00480	COG3261	NADH dehydrogenase
FPK02_RS00545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS00590	COG0657	acetylesterase activity
FPK02_RS00600	COG2755	lipolytic protein G-D-S-L family
FPK02_RS00600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FPK02_RS00630	COG1376	ErfK ybiS ycfS ynhG family protein
FPK02_RS00635	COG0583	DNA-binding transcription factor activity
FPK02_RS00640	COG0028	Belongs to the TPP enzyme family
FPK02_RS00675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK02_RS00710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS00720	COG0596	Alpha beta hydrolase
FPK02_RS00765	COG0038	chloride channel
FPK02_RS00770	COG1309	transcriptional regulator
FPK02_RS00785	COG1012	belongs to the aldehyde dehydrogenase family
FPK02_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS00795	COG0604	alcohol dehydrogenase
FPK02_RS00795	COG3321	synthase
FPK02_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS00815	COG3391	amine dehydrogenase activity
FPK02_RS00820	COG2365	Tyrosine phosphatase family
FPK02_RS00855	COG1309	transcriptional regulator
FPK02_RS00860	COG0657	acetylesterase activity
FPK02_RS00860	COG5651	PPE family
FPK02_RS00865	COG0657	acetylesterase activity
FPK02_RS00865	COG5651	PPE family
FPK02_RS00870	COG0277	FAD linked oxidase domain protein
FPK02_RS00875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FPK02_RS00900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK02_RS00905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK02_RS00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK02_RS00980	COG2267	carboxylic ester hydrolase activity
FPK02_RS00995	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK02_RS01005	COG4122	O-methyltransferase activity
FPK02_RS01020	COG1937	Protein conserved in bacteria
FPK02_RS01025	COG2814	Major facilitator Superfamily
FPK02_RS01030	COG1376	ErfK ybiS ycfS ynhG family protein
FPK02_RS01040	COG1132	(ABC) transporter
FPK02_RS01055	COG0243	molybdopterin cofactor binding
FPK02_RS01060	COG3590	peptidase
FPK02_RS01100	COG2409	Drug exporters of the RND superfamily
FPK02_RS01155	COG0657	acetylesterase activity
FPK02_RS01160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPK02_RS01170	COG0657	acetylesterase activity
FPK02_RS01180	COG1024	Enoyl-CoA hydratase
FPK02_RS01190	COG0500	methyltransferase
FPK02_RS01195	COG0297	glycogen (starch) synthase activity
FPK02_RS01215	COG1487	ribonuclease activity
FPK02_RS01255	COG4981	capsule polysaccharide biosynthetic process
FPK02_RS01265	COG1472	Belongs to the glycosyl hydrolase 3 family
FPK02_RS01285	COG2030	dehydratase
FPK02_RS01295	COG0183	Belongs to the thiolase family
FPK02_RS01300	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS01320	COG1053	succinate dehydrogenase
FPK02_RS01340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPK02_RS01340	COG2146	nitrite reductase [NAD(P)H] activity
FPK02_RS01360	COG5651	PPE family
FPK02_RS01390	COG1984	allophanate hydrolase subunit 2
FPK02_RS01410	COG2223	nitrite transmembrane transporter activity
FPK02_RS01415	COG2161	toxin-antitoxin pair type II binding
FPK02_RS01430	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS01435	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS01450	COG0346	lactoylglutathione lyase activity
FPK02_RS01480	COG3391	amine dehydrogenase activity
FPK02_RS01490	COG5651	PPE family
FPK02_RS01545	COG1404	Belongs to the peptidase S8 family
FPK02_RS01570	COG1368	sulfuric ester hydrolase activity
FPK02_RS01575	COG3391	amine dehydrogenase activity
FPK02_RS01615	COG0778	Nitroreductase
FPK02_RS01625	COG0671	phosphoesterase, PA-phosphatase related
FPK02_RS01695	COG0717	Belongs to the dCTP deaminase family
FPK02_RS01700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FPK02_RS01705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPK02_RS01730	COG2226	methyltransferase
FPK02_RS01740	COG1252	NADH dehydrogenase
FPK02_RS01775	COG2181	nitrate reductase activity
FPK02_RS01775	COG0247	lactate metabolic process
FPK02_RS01850	COG0789	Transcriptional regulator
FPK02_RS01860	COG5263	repeat protein
FPK02_RS01860	COG5651	PPE family
FPK02_RS01880	COG1994	Peptidase M50
FPK02_RS01895	COG2239	Acts as a magnesium transporter
FPK02_RS01940	COG0746	molybdenum cofactor guanylyltransferase activity
FPK02_RS01980	COG3360	Dodecin
FPK02_RS02025	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FPK02_RS02040	COG1252	NADH dehydrogenase
FPK02_RS02050	COG1403	HNH endonuclease
FPK02_RS02090	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS02115	COG0604	alcohol dehydrogenase
FPK02_RS02115	COG0604	alcohol dehydrogenase
FPK02_RS02115	COG3321	synthase
FPK02_RS02115	COG3321	synthase
FPK02_RS02120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK02_RS02145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPK02_RS02185	COG2234	aminopeptidase activity
FPK02_RS02220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPK02_RS02270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPK02_RS02275	COG1183	phosphatidylcholine synthase activity
FPK02_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS02315	COG5343	regulation of RNA biosynthetic process
FPK02_RS02330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS02375	COG1024	Enoyl-CoA hydratase
FPK02_RS02390	COG1505	serine-type exopeptidase activity
FPK02_RS02450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS02475	COG2733	membrane
FPK02_RS02680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPK02_RS02680	COG1648	precorrin-2 dehydrogenase activity
FPK02_RS02705	COG1366	Belongs to the anti-sigma-factor antagonist family
FPK02_RS02710	COG2755	lipolytic protein G-D-S-L family
FPK02_RS02710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FPK02_RS02715	COG2755	lipolytic protein G-D-S-L family
FPK02_RS02735	COG1113	amino acid transport
FPK02_RS02750	COG0406	alpha-ribazole phosphatase activity
FPK02_RS02760	COG0785	Cytochrome C biogenesis protein
FPK02_RS02770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPK02_RS02790	COG3391	amine dehydrogenase activity
FPK02_RS02805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FPK02_RS02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPK02_RS02855	COG0306	phosphate transporter
FPK02_RS02865	COG4221	oxidoreductase activity
FPK02_RS02885	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS02890	COG1228	amidohydrolase
FPK02_RS02940	COG0142	geranyltranstransferase activity
FPK02_RS02970	COG2345	Transcriptional regulator
FPK02_RS02985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPK02_RS03045	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
FPK02_RS03055	COG3537	Alpha-1,2-mannosidase
FPK02_RS03075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK02_RS03100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK02_RS03110	COG1487	ribonuclease activity
FPK02_RS03130	COG2002	toxin-antitoxin pair type II binding
FPK02_RS03140	COG2972	Histidine kinase
FPK02_RS03145	COG0745	RESPONSE REGULATOR receiver
FPK02_RS03210	COG0653	protein targeting
FPK02_RS03240	COG1085	galactose-1-phosphate uridylyltransferase
FPK02_RS03245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FPK02_RS03280	COG1487	ribonuclease activity
FPK02_RS03300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FPK02_RS03345	COG2030	dehydratase
FPK02_RS03375	COG0081	regulation of translation
FPK02_RS03380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS03385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS03390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS03395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS03435	COG1309	transcriptional regulator
FPK02_RS03510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FPK02_RS03535	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS03550	COG1024	Enoyl-CoA hydratase
FPK02_RS03565	COG1510	regulation of RNA biosynthetic process
FPK02_RS03580	COG1309	transcriptional regulator
FPK02_RS03640	COG0535	radical SAM domain protein
FPK02_RS03740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FPK02_RS03795	COG0200	Binds to the 23S rRNA
FPK02_RS03800	COG0616	signal peptide processing
FPK02_RS03815	COG0235	Class ii aldolase
FPK02_RS03820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPK02_RS03905	COG0657	acetylesterase activity
FPK02_RS03975	COG0406	alpha-ribazole phosphatase activity
FPK02_RS04000	COG0745	RESPONSE REGULATOR receiver
FPK02_RS04005	COG2205	protein histidine kinase activity
FPK02_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS04100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPK02_RS04130	COG0477	Major facilitator Superfamily
FPK02_RS04140	COG3573	Dehydrogenase
FPK02_RS04155	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPK02_RS04175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS04180	COG2188	Transcriptional regulator
FPK02_RS04185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FPK02_RS04190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPK02_RS04200	COG3547	Transposase (IS116 IS110 IS902 family)
FPK02_RS04210	COG2837	iron assimilation
FPK02_RS04260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPK02_RS04305	COG0745	RESPONSE REGULATOR receiver
FPK02_RS04350	COG0640	Transcriptional regulator
FPK02_RS04355	COG0590	tRNA wobble adenosine to inosine editing
FPK02_RS04395	COG3391	amine dehydrogenase activity
FPK02_RS04435	COG4106	trans-aconitate 2-methyltransferase activity
FPK02_RS04440	COG0596	Alpha beta hydrolase
FPK02_RS04450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPK02_RS04460	COG4585	Histidine kinase
FPK02_RS04465	COG2132	Multicopper oxidase
FPK02_RS04475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPK02_RS04510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPK02_RS04530	COG0183	Belongs to the thiolase family
FPK02_RS04535	COG1024	Enoyl-CoA hydratase
FPK02_RS04535	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPK02_RS04560	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPK02_RS04585	COG3304	Inner membrane component domain
FPK02_RS04590	COG1278	Cold shock
FPK02_RS04810	COG0183	Belongs to the thiolase family
FPK02_RS04850	COG3328	transposase activity
FPK02_RS04900	COG0581	inorganic phosphate transmembrane transporter activity
FPK02_RS04940	COG3285	dna ligase
FPK02_RS04940	COG1793	dna ligase
FPK02_RS04970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPK02_RS05000	COG0739	heme binding
FPK02_RS05005	COG0045	succinate-CoA ligase (ADP-forming) activity
FPK02_RS05105	COG1024	Enoyl-CoA hydratase
FPK02_RS05120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPK02_RS05135	COG0657	acetylesterase activity
FPK02_RS05140	COG3391	amine dehydrogenase activity
FPK02_RS05155	COG3391	amine dehydrogenase activity
FPK02_RS05160	COG0745	RESPONSE REGULATOR receiver
FPK02_RS05165	COG2205	protein histidine kinase activity
FPK02_RS05165	COG2972	Histidine kinase
FPK02_RS05170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK02_RS05175	COG0315	cyclic pyranopterin monophosphate synthase activity
FPK02_RS05175	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPK02_RS05180	COG1970	mechanosensitive ion channel activity
FPK02_RS05190	COG0577	efflux transmembrane transporter activity
FPK02_RS05200	COG0142	geranyltranstransferase activity
FPK02_RS05215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPK02_RS05220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPK02_RS05255	COG4106	trans-aconitate 2-methyltransferase activity
FPK02_RS05260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPK02_RS05260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPK02_RS05300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPK02_RS05315	COG0084	hydrolase, TatD family'
FPK02_RS05340	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS05385	COG3956	TIGRFAM MazG family protein
FPK02_RS05450	COG2205	protein histidine kinase activity
FPK02_RS05455	COG0745	RESPONSE REGULATOR receiver
FPK02_RS05480	COG0657	acetylesterase activity
FPK02_RS05495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK02_RS05510	COG3328	transposase activity
FPK02_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS05570	COG3391	amine dehydrogenase activity
FPK02_RS05575	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS05655	COG0183	Belongs to the thiolase family
FPK02_RS05660	COG2755	lipolytic protein G-D-S-L family
FPK02_RS05665	COG0657	acetylesterase activity
FPK02_RS05705	COG1331	Highly conserved protein containing a thioredoxin domain
FPK02_RS05770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FPK02_RS05850	COG0012	GTP binding
FPK02_RS05905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPK02_RS05915	COG0596	Alpha beta hydrolase
FPK02_RS05930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPK02_RS05930	COG0574	Belongs to the PEP-utilizing enzyme family
FPK02_RS05935	COG1403	HNH endonuclease
FPK02_RS05940	COG3800	Transcriptional regulator
FPK02_RS05940	COG1396	sequence-specific DNA binding
FPK02_RS05975	COG0183	Belongs to the thiolase family
FPK02_RS05990	COG1755	Isoprenylcysteine carboxyl methyltransferase
FPK02_RS06000	COG1024	Enoyl-CoA hydratase
FPK02_RS06005	COG1024	Enoyl-CoA hydratase
FPK02_RS06010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPK02_RS06050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FPK02_RS06060	COG3467	pyridoxamine 5'-phosphate
FPK02_RS06110	COG1140	nitrate reductase beta subunit
FPK02_RS06125	COG1217	gtp-binding protein TYPA
FPK02_RS06175	COG1902	pentaerythritol trinitrate reductase activity
FPK02_RS06175	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPK02_RS06185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPK02_RS06200	COG0604	alcohol dehydrogenase
FPK02_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS06200	COG3321	synthase
FPK02_RS06215	COG5651	PPE family
FPK02_RS06225	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPK02_RS06225	COG2508	Transcriptional regulator
FPK02_RS06230	COG1012	belongs to the aldehyde dehydrogenase family
FPK02_RS06235	COG0506	proline dehydrogenase activity
FPK02_RS06245	COG0596	Alpha beta hydrolase
FPK02_RS06260	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS06270	COG0657	acetylesterase activity
FPK02_RS06275	COG5651	PPE family
FPK02_RS06280	COG4842	Belongs to the WXG100 family
FPK02_RS06290	COG3328	transposase activity
FPK02_RS06295	COG0477	Major facilitator Superfamily
FPK02_RS06315	COG1611	Belongs to the LOG family
FPK02_RS06320	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS06340	COG0519	Catalyzes the synthesis of GMP from XMP
FPK02_RS06375	COG3559	Exporter of polyketide antibiotics
FPK02_RS06380	COG1131	(ABC) transporter
FPK02_RS06385	COG1309	transcriptional regulator
FPK02_RS06400	COG5662	AntiSigma factor
FPK02_RS06405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPK02_RS06410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPK02_RS06455	COG2239	Acts as a magnesium transporter
FPK02_RS06490	COG0598	Magnesium transport protein CorA
FPK02_RS06525	COG2026	Addiction module toxin, RelE StbE family
FPK02_RS06530	COG2161	toxin-antitoxin pair type II binding
FPK02_RS06535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPK02_RS06535	COG0567	Dehydrogenase, E1 component
FPK02_RS06580	COG0277	FAD linked oxidase domain protein
FPK02_RS06940	COG0346	lactoylglutathione lyase activity
FPK02_RS06960	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FPK02_RS06970	COG0058	SHG alpha-glucan phosphorylase activity
FPK02_RS07020	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FPK02_RS07155	COG5651	PPE family
FPK02_RS07230	COG2226	methyltransferase
FPK02_RS07305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPK02_RS07310	COG2072	flavoprotein involved in K transport
FPK02_RS07315	COG2124	cytochrome p450
FPK02_RS07345	COG0657	acetylesterase activity
FPK02_RS07470	COG0657	acetylesterase activity
FPK02_RS07475	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS07490	COG3391	amine dehydrogenase activity
FPK02_RS07490	COG5651	PPE family
FPK02_RS07505	COG1376	ErfK ybiS ycfS ynhG family protein
FPK02_RS07530	COG0149	triose-phosphate isomerase activity
FPK02_RS07555	COG0657	acetylesterase activity
FPK02_RS07595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPK02_RS07600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FPK02_RS07605	COG0657	acetylesterase activity
FPK02_RS07615	COG0657	acetylesterase activity
FPK02_RS07645	COG1131	(ABC) transporter
FPK02_RS07670	COG0396	ATPase activity
FPK02_RS07685	COG2151	metal-sulfur cluster biosynthetic enzyme
FPK02_RS07690	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS07710	COG3118	belongs to the thioredoxin family
FPK02_RS07720	COG0488	(ABC) transporter
FPK02_RS07730	COG1309	transcriptional regulator
FPK02_RS07735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FPK02_RS07745	COG3883	PFAM NLP P60 protein
FPK02_RS07745	COG0791	NLP P60 protein
FPK02_RS07755	COG0714	Associated with various cellular activities
FPK02_RS07765	COG2304	oxidoreductase activity
FPK02_RS07850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPK02_RS07855	COG2226	methyltransferase
FPK02_RS07860	COG3360	Dodecin
FPK02_RS07880	COG1621	beta-fructofuranosidase activity
FPK02_RS07915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FPK02_RS07935	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FPK02_RS07940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPK02_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS08015	COG0604	alcohol dehydrogenase
FPK02_RS08015	COG3321	synthase
FPK02_RS08045	COG2070	2-Nitropropane dioxygenase
FPK02_RS08100	COG0300	oxidoreductase activity
FPK02_RS08210	COG0791	NLP P60 protein
FPK02_RS08210	COG3883	PFAM NLP P60 protein
FPK02_RS08330	COG1073	alpha beta
FPK02_RS08390	COG0483	inositol monophosphate 1-phosphatase activity
FPK02_RS08395	COG0107	imidazoleglycerol-phosphate synthase activity
FPK02_RS08405	COG0387	Pfam Sodium calcium exchanger
FPK02_RS08465	COG1946	Acyl-CoA thioesterase
FPK02_RS08470	COG0456	acetyltransferase
FPK02_RS08470	COG0454	-acetyltransferase
FPK02_RS08475	COG1132	(ABC) transporter
FPK02_RS08480	COG4988	ABC transporter
FPK02_RS08485	COG1294	oxidase, subunit
FPK02_RS08490	COG1271	oxidase subunit
FPK02_RS08565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK02_RS08585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FPK02_RS08585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FPK02_RS08615	COG0657	acetylesterase activity
FPK02_RS08630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FPK02_RS08700	COG3321	synthase
FPK02_RS08700	COG0604	alcohol dehydrogenase
FPK02_RS08700	COG0604	alcohol dehydrogenase
FPK02_RS08700	COG3321	synthase
FPK02_RS08715	COG0488	(ABC) transporter
FPK02_RS08780	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS08785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FPK02_RS08805	COG2835	tetraacyldisaccharide 4'-kinase activity
FPK02_RS08845	COG0647	UMP catabolic process
FPK02_RS08885	COG0494	nUDIX hydrolase
FPK02_RS08905	COG4122	O-methyltransferase activity
FPK02_RS08910	COG1113	amino acid transport
FPK02_RS08915	COG5651	PPE family
FPK02_RS08930	COG0659	secondary active sulfate transmembrane transporter activity
FPK02_RS08940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FPK02_RS08945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPK02_RS08985	COG3246	L-lysine catabolic process to acetate
FPK02_RS09130	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FPK02_RS09140	COG0842	Transport permease protein
FPK02_RS09140	COG1131	(ABC) transporter
FPK02_RS09140	COG1716	ATPase activity
FPK02_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS09170	COG5263	repeat protein
FPK02_RS09170	COG5651	PPE family
FPK02_RS09195	COG0438	transferase activity, transferring glycosyl groups
FPK02_RS09230	COG1937	Protein conserved in bacteria
FPK02_RS09330	COG5651	PPE family
FPK02_RS09340	COG5651	PPE family
FPK02_RS09345	COG5651	PPE family
FPK02_RS09375	COG1404	Belongs to the peptidase S8 family
FPK02_RS09395	COG5651	PPE family
FPK02_RS09410	COG0657	acetylesterase activity
FPK02_RS09430	COG0657	acetylesterase activity
FPK02_RS09445	COG5651	PPE family
FPK02_RS09455	COG1285	pathogenesis
FPK02_RS09535	COG0509	glycine decarboxylation via glycine cleavage system
FPK02_RS09560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPK02_RS09560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPK02_RS09605	COG1253	flavin adenine dinucleotide binding
FPK02_RS09610	COG1253	flavin adenine dinucleotide binding
FPK02_RS09620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FPK02_RS09655	COG0830	nickel cation binding
FPK02_RS09675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS09725	COG4221	oxidoreductase activity
FPK02_RS09730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPK02_RS09735	COG0183	Belongs to the thiolase family
FPK02_RS09795	COG0174	glutamine synthetase
FPK02_RS09815	COG0300	oxidoreductase activity
FPK02_RS09825	COG1652	LysM domain
FPK02_RS09835	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FPK02_RS09850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FPK02_RS09855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FPK02_RS09880	COG2070	2-Nitropropane dioxygenase
FPK02_RS09895	COG1490	D-aminoacyl-tRNA deacylase activity
FPK02_RS09930	COG1950	PFAM Membrane protein of
FPK02_RS09935	COG1366	Belongs to the anti-sigma-factor antagonist family
FPK02_RS09955	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FPK02_RS09990	COG2224	Isocitrate lyase
FPK02_RS10000	COG5651	PPE family
FPK02_RS10000	COG5263	repeat protein
FPK02_RS10005	COG5651	PPE family
FPK02_RS10005	COG5263	repeat protein
FPK02_RS10025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPK02_RS10030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPK02_RS10040	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS10085	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS10090	COG1024	Enoyl-CoA hydratase
FPK02_RS10100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FPK02_RS10100	COG0543	2 iron, 2 sulfur cluster binding
FPK02_RS10105	COG0596	Alpha beta hydrolase
FPK02_RS10115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPK02_RS10115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPK02_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS10125	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPK02_RS10135	COG0653	protein targeting
FPK02_RS10180	COG4691	Plasmid stability protein
FPK02_RS10240	COG1309	transcriptional regulator
FPK02_RS10275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK02_RS10355	COG1872	DUF167
FPK02_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS10550	COG2442	InterPro IPR007367
FPK02_RS10565	COG1396	sequence-specific DNA binding
FPK02_RS10570	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FPK02_RS10635	COG0640	Transcriptional regulator
FPK02_RS10650	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPK02_RS10655	COG3842	ATPase activity
FPK02_RS10660	COG0395	ABC-type sugar transport system, permease component
FPK02_RS10665	COG1175	transmembrane transport
FPK02_RS10680	COG1335	isochorismatase
FPK02_RS10705	COG3321	synthase
FPK02_RS10705	COG0604	alcohol dehydrogenase
FPK02_RS10760	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPK02_RS10780	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPK02_RS10805	COG2367	Beta-lactamase
FPK02_RS10825	COG2242	protein methyltransferase activity
FPK02_RS10825	COG2241	protein methyltransferase activity
FPK02_RS10830	COG0300	oxidoreductase activity
FPK02_RS10860	COG1511	domain protein
FPK02_RS10895	COG2801	Transposase and inactivated derivatives
FPK02_RS10910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPK02_RS10960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPK02_RS10965	COG4279	zinc finger
FPK02_RS10970	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FPK02_RS10980	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FPK02_RS10995	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FPK02_RS11065	COG5651	PPE family
FPK02_RS11070	COG1410	methionine synthase
FPK02_RS11070	COG0646	methionine synthase
FPK02_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS11150	COG0167	dihydroorotate dehydrogenase activity
FPK02_RS11160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPK02_RS11215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FPK02_RS11230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPK02_RS11280	COG0768	penicillin binding
FPK02_RS11320	COG0142	geranyltranstransferase activity
FPK02_RS11350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FPK02_RS11380	COG0003	Pfam Anion-transporting ATPase
FPK02_RS11395	COG1022	Amp-dependent synthetase and ligase
FPK02_RS11475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPK02_RS11505	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FPK02_RS11530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPK02_RS11550	COG0321	lipoyl(octanoyl) transferase activity
FPK02_RS11605	COG5607	PFAM CHAD domain containing protein
FPK02_RS11605	COG3025	triphosphatase activity
FPK02_RS11640	COG3744	PilT protein domain protein
FPK02_RS11665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FPK02_RS11800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FPK02_RS11805	COG4221	oxidoreductase activity
FPK02_RS11900	COG0657	acetylesterase activity
FPK02_RS12010	COG1073	alpha beta
FPK02_RS12035	COG2442	InterPro IPR007367
FPK02_RS12100	COG0395	ABC-type sugar transport system, permease component
FPK02_RS12115	COG0531	amino acid
FPK02_RS12120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPK02_RS12125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPK02_RS12130	COG1834	amidinotransferase
FPK02_RS12135	COG1522	sequence-specific DNA binding
FPK02_RS12160	COG2223	nitrite transmembrane transporter activity
FPK02_RS12180	COG0477	Major facilitator Superfamily
FPK02_RS12190	COG1045	serine acetyltransferase
FPK02_RS12205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FPK02_RS12395	COG0657	acetylesterase activity
FPK02_RS12410	COG1420	regulation of RNA biosynthetic process
FPK02_RS12440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS12455	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FPK02_RS12455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS12460	COG1021	2,3-dihydroxybenzoate-AMP ligase
FPK02_RS12520	COG1297	OPT oligopeptide transporter protein
FPK02_RS12545	COG4208	sulfate ABC transporter
FPK02_RS12555	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FPK02_RS12570	COG3387	PFAM Glycoside hydrolase 15-related
FPK02_RS12595	COG1234	tRNA 3'-trailer cleavage
FPK02_RS12605	COG1305	Transglutaminase-like
FPK02_RS12635	COG1555	photosystem II stabilization
FPK02_RS12635	COG1596	polysaccharide export
FPK02_RS12650	COG2755	lipolytic protein G-D-S-L family
FPK02_RS12660	COG0799	negative regulation of ribosome biogenesis
FPK02_RS12665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPK02_RS12690	COG0542	response to heat
FPK02_RS12715	COG5651	PPE family
FPK02_RS12735	COG0668	transmembrane transport
FPK02_RS12740	COG5002	protein histidine kinase activity
FPK02_RS12745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPK02_RS12760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FPK02_RS12780	COG1301	dicarboxylic acid transport
FPK02_RS12785	COG1530	ribonuclease E activity
FPK02_RS12800	COG0285	dihydrofolate synthase activity
FPK02_RS12810	COG3268	Saccharopine dehydrogenase
FPK02_RS12815	COG1388	LysM domain
FPK02_RS12835	COG1013	pyruvate-flavodoxin oxidoreductase activity
FPK02_RS12840	COG0674	pyruvate-flavodoxin oxidoreductase activity
FPK02_RS12840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FPK02_RS12850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FPK02_RS12855	COG2040	homocysteine
FPK02_RS12875	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPK02_RS12890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPK02_RS12905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPK02_RS12935	COG0366	Alpha amylase catalytic
FPK02_RS12955	COG0824	Thioesterase
FPK02_RS12960	COG2902	Dehydrogenase
FPK02_RS12995	COG0657	acetylesterase activity
FPK02_RS13010	COG0657	acetylesterase activity
FPK02_RS13050	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FPK02_RS13055	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPK02_RS13075	COG2030	dehydratase
FPK02_RS13080	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS13090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPK02_RS13105	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS13125	COG0300	oxidoreductase activity
FPK02_RS13130	COG0433	COG0433 Predicted ATPase
FPK02_RS13145	COG3328	transposase activity
FPK02_RS13175	COG1376	ErfK ybiS ycfS ynhG family protein
FPK02_RS13215	COG3757	hydrolase, family 25
FPK02_RS13230	COG1715	Restriction endonuclease
FPK02_RS13265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPK02_RS13330	COG1487	ribonuclease activity
FPK02_RS13370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPK02_RS13380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPK02_RS13385	COG0432	Pfam Uncharacterised protein family UPF0047
FPK02_RS13405	COG5473	translation initiation factor activity
FPK02_RS13495	COG0596	Alpha beta hydrolase
FPK02_RS13530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPK02_RS13550	COG1022	Amp-dependent synthetase and ligase
FPK02_RS13550	COG3320	Male sterility
FPK02_RS13630	COG1946	Acyl-CoA thioesterase
FPK02_RS13645	COG5651	PPE family
FPK02_RS13685	COG3391	amine dehydrogenase activity
FPK02_RS13690	COG4762	Protein conserved in bacteria
FPK02_RS13805	COG1366	Belongs to the anti-sigma-factor antagonist family
FPK02_RS13825	COG0640	Transcriptional regulator
FPK02_RS13830	COG0798	PFAM Bile acid sodium symporter
FPK02_RS13935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPK02_RS14005	COG1131	(ABC) transporter
FPK02_RS14015	COG0531	amino acid
FPK02_RS14020	COG0569	domain protein
FPK02_RS14160	COG1388	LysM domain
FPK02_RS14165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FPK02_RS14185	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS14190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPK02_RS14220	COG1196	nuclear chromosome segregation
FPK02_RS14270	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
FPK02_RS14275	COG3391	amine dehydrogenase activity
FPK02_RS14300	COG1842	Phage shock protein A
FPK02_RS14315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FPK02_RS14360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FPK02_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS14445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FPK02_RS14475	COG1522	sequence-specific DNA binding
FPK02_RS14480	COG0686	Belongs to the AlaDH PNT family
FPK02_RS14525	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS14530	COG0183	Belongs to the thiolase family
FPK02_RS14550	COG2977	Belongs to the P-Pant transferase superfamily
FPK02_RS14555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FPK02_RS14585	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPK02_RS14590	COG3609	addiction module antidote protein, CC2985 family
FPK02_RS14695	COG1353	crispr-associated protein
FPK02_RS14730	COG3744	PilT protein domain protein
FPK02_RS14735	COG4118	positive regulation of growth
FPK02_RS14745	COG3842	ATPase activity
FPK02_RS14750	COG1653	transport
FPK02_RS14755	COG0395	ABC-type sugar transport system, permease component
FPK02_RS14770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPK02_RS14820	COG1648	precorrin-2 dehydrogenase activity
FPK02_RS14820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPK02_RS14865	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FPK02_RS14890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPK02_RS14925	COG2161	toxin-antitoxin pair type II binding
FPK02_RS14930	COG2026	Addiction module toxin, RelE StbE family
FPK02_RS15010	COG0233	cytoplasmic translational termination
FPK02_RS15020	COG0745	RESPONSE REGULATOR receiver
FPK02_RS15045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPK02_RS15155	COG1686	Belongs to the peptidase S11 family
FPK02_RS15190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FPK02_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS15270	COG3321	synthase
FPK02_RS15270	COG0604	alcohol dehydrogenase
FPK02_RS15350	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS15400	COG1819	glycosyl
FPK02_RS15425	COG0701	Predicted permease
FPK02_RS15445	COG0742	ribosomal rna small subunit methyltransferase
FPK02_RS15450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FPK02_RS15465	COG0657	acetylesterase activity
FPK02_RS15475	COG0656	L-ascorbic acid biosynthetic process
FPK02_RS15525	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPK02_RS15560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPK02_RS15590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPK02_RS15595	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPK02_RS15605	COG0473	3-isopropylmalate dehydrogenase activity
FPK02_RS15635	COG0390	transport system, permease component
FPK02_RS15660	COG2259	Doxx family
FPK02_RS15690	COG0154	amidase activity
FPK02_RS15735	COG3328	transposase activity
FPK02_RS15795	COG0110	maltose O-acetyltransferase activity
FPK02_RS15800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPK02_RS15830	COG1119	ATPase activity
FPK02_RS15835	COG0560	Phosphoserine phosphatase
FPK02_RS15835	COG3830	Belongs to the UPF0237 family
FPK02_RS15875	COG1309	transcriptional regulator
FPK02_RS15925	COG2186	Transcriptional regulator
FPK02_RS15930	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS15940	COG1966	Carbon starvation protein
FPK02_RS16025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS16080	COG2354	Protein conserved in bacteria
FPK02_RS16105	COG0657	acetylesterase activity
FPK02_RS16115	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPK02_RS16135	COG2177	Part of the ABC transporter FtsEX involved in
FPK02_RS16140	COG2884	Cell division ATP-binding protein ftsE
FPK02_RS16150	COG0668	transmembrane transport
FPK02_RS16165	COG0277	FAD linked oxidase domain protein
FPK02_RS16180	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPK02_RS16190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FPK02_RS16205	COG3328	transposase activity
FPK02_RS16255	COG3629	intracellular signal transduction
FPK02_RS16275	COG2801	Transposase and inactivated derivatives
FPK02_RS16325	COG0483	inositol monophosphate 1-phosphatase activity
FPK02_RS16340	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS16345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS16345	COG3321	synthase
FPK02_RS16345	COG4221	oxidoreductase activity
FPK02_RS16345	COG0604	alcohol dehydrogenase
FPK02_RS16395	COG1034	ATP synthesis coupled electron transport
FPK02_RS16405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPK02_RS16460	COG0714	Associated with various cellular activities
FPK02_RS16505	COG1309	transcriptional regulator
FPK02_RS16515	COG0154	amidase activity
FPK02_RS16530	COG0748	coenzyme F420 binding
FPK02_RS16555	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FPK02_RS16560	COG1396	sequence-specific DNA binding
FPK02_RS16590	COG2826	transposase and inactivated derivatives, IS30 family
FPK02_RS16610	COG1615	UPF0182 protein
FPK02_RS16635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FPK02_RS16655	COG2816	NAD+ diphosphatase activity
FPK02_RS16665	COG0210	DNA helicase
FPK02_RS16680	COG0596	Alpha beta hydrolase
FPK02_RS16685	COG3695	enzyme binding
FPK02_RS16725	COG0513	Belongs to the DEAD box helicase family
FPK02_RS16740	COG0406	alpha-ribazole phosphatase activity
FPK02_RS16760	COG1597	lipid kinase activity
FPK02_RS16795	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS16800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPK02_RS16810	COG2135	peptidase activity
FPK02_RS16815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPK02_RS16820	COG1162	GTPase activity
FPK02_RS16840	COG2326	polyphosphate kinase activity
FPK02_RS16860	COG4651	solute:proton antiporter activity
FPK02_RS16860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPK02_RS16870	COG2020	methyltransferase activity
FPK02_RS16885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FPK02_RS16905	COG5000	phosphorelay sensor kinase activity
FPK02_RS16905	COG5002	protein histidine kinase activity
FPK02_RS16940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPK02_RS16945	COG0531	amino acid
FPK02_RS16950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPK02_RS16955	COG1482	cell wall glycoprotein biosynthetic process
FPK02_RS16965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPK02_RS17015	COG1316	TRANSCRIPTIONal
FPK02_RS17040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FPK02_RS17045	COG0659	secondary active sulfate transmembrane transporter activity
FPK02_RS17080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPK02_RS17090	COG0424	maF-like protein
FPK02_RS17105	COG4770	biotin carboxylase activity
FPK02_RS17135	COG1522	sequence-specific DNA binding
FPK02_RS17145	COG1012	belongs to the aldehyde dehydrogenase family
FPK02_RS17155	COG1309	transcriptional regulator
FPK02_RS17160	COG1201	RNA secondary structure unwinding
FPK02_RS17175	COG3408	Glycogen debranching enzyme
FPK02_RS17175	COG3119	arylsulfatase activity
FPK02_RS17180	COG0564	pseudouridine synthase activity
FPK02_RS17205	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FPK02_RS17205	COG1473	amidohydrolase
FPK02_RS17220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPK02_RS17230	COG3511	phospholipase C
FPK02_RS17270	COG2009	succinate dehydrogenase
FPK02_RS17280	COG1053	succinate dehydrogenase
FPK02_RS17285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPK02_RS17315	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPK02_RS17345	COG1595	DNA-templated transcription, initiation
FPK02_RS17350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPK02_RS17355	COG1686	Belongs to the peptidase S11 family
FPK02_RS17360	COG2814	Major facilitator Superfamily
FPK02_RS17365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPK02_RS17375	COG0789	Transcriptional regulator
FPK02_RS17380	COG1295	ribonuclease BN
FPK02_RS17400	COG2873	o-acetylhomoserine
FPK02_RS17425	COG0657	acetylesterase activity
FPK02_RS17435	COG5651	PPE family
FPK02_RS17435	COG5651	PPE family
FPK02_RS17475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FPK02_RS17495	COG1716	ATPase activity
FPK02_RS17495	COG0842	Transport permease protein
FPK02_RS17495	COG1131	(ABC) transporter
FPK02_RS17500	COG1357	PFAM Pentapeptide repeats (8 copies)
FPK02_RS17515	COG2018	Roadblock/LC7 domain
FPK02_RS17525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FPK02_RS17550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS17580	COG1657	PFAM Prenyltransferase squalene oxidase
FPK02_RS17600	COG0142	geranyltranstransferase activity
FPK02_RS17605	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FPK02_RS17625	COG2030	dehydratase
FPK02_RS17630	COG0406	alpha-ribazole phosphatase activity
FPK02_RS17640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS17790	COG0456	acetyltransferase
FPK02_RS17820	COG5651	PPE family
FPK02_RS17830	COG1484	DNA-dependent DNA replication
FPK02_RS17850	COG5651	PPE family
FPK02_RS17885	COG0076	glutamate decarboxylase activity
FPK02_RS17945	COG4842	Belongs to the WXG100 family
FPK02_RS17950	COG4842	Belongs to the WXG100 family
FPK02_RS17960	COG1674	ftsk spoiiie
FPK02_RS17970	COG1404	Belongs to the peptidase S8 family
FPK02_RS18015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FPK02_RS18030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FPK02_RS18055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPK02_RS18060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPK02_RS18065	COG0028	Belongs to the TPP enzyme family
FPK02_RS18085	COG0477	Major facilitator Superfamily
FPK02_RS18095	COG5651	PPE family
FPK02_RS18100	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPK02_RS18105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS18125	COG1316	TRANSCRIPTIONal
FPK02_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS18135	COG2259	Doxx family
FPK02_RS18140	COG0657	acetylesterase activity
FPK02_RS18145	COG1695	Transcriptional regulator
FPK02_RS18155	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FPK02_RS18180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FPK02_RS18205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK02_RS18210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FPK02_RS18225	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18230	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18235	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS18240	COG0657	acetylesterase activity
FPK02_RS18245	COG0657	acetylesterase activity
FPK02_RS18250	COG0028	Belongs to the TPP enzyme family
FPK02_RS18260	COG0657	acetylesterase activity
FPK02_RS18285	COG0657	acetylesterase activity
FPK02_RS18295	COG1024	Enoyl-CoA hydratase
FPK02_RS18305	COG2124	cytochrome p450
FPK02_RS18315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPK02_RS18325	COG0183	Belongs to the thiolase family
FPK02_RS18330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FPK02_RS18345	COG4638	Rieske (2fe-2S)
FPK02_RS18370	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS18400	COG3971	2-oxopent-4-enoate hydratase activity
FPK02_RS18405	COG1053	succinate dehydrogenase
FPK02_RS18410	COG2030	dehydratase
FPK02_RS18430	COG2030	dehydratase
FPK02_RS18435	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18440	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18450	COG0183	Belongs to the thiolase family
FPK02_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS18470	COG1024	Enoyl-CoA hydratase
FPK02_RS18490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FPK02_RS18500	COG0183	Belongs to the thiolase family
FPK02_RS18520	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18525	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS18530	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18535	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18540	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18545	COG0436	Aminotransferase
FPK02_RS18595	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS18600	COG1309	transcriptional regulator
FPK02_RS18605	COG1609	Transcriptional regulator
FPK02_RS18625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPK02_RS18660	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FPK02_RS18680	COG0657	acetylesterase activity
FPK02_RS18700	COG0739	heme binding
FPK02_RS18775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPK02_RS18805	COG2267	carboxylic ester hydrolase activity
FPK02_RS18855	COG2027	D-alanyl-D-alanine carboxypeptidase
FPK02_RS18870	COG2244	polysaccharide biosynthetic process
FPK02_RS18910	COG3328	transposase activity
FPK02_RS18915	COG2184	nucleotidyltransferase activity
FPK02_RS18935	COG0470	DNA polymerase III
FPK02_RS18960	COG1205	dead DEAH box helicase
FPK02_RS18960	COG1111	helicase
FPK02_RS18965	COG0657	acetylesterase activity
FPK02_RS19030	COG4172	Belongs to the ABC transporter superfamily
FPK02_RS19035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPK02_RS19040	COG0601	transmembrane transport
FPK02_RS19075	COG0494	nUDIX hydrolase
FPK02_RS19100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPK02_RS19135	COG1408	metallophosphoesterase
FPK02_RS19140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPK02_RS19190	COG0714	Associated with various cellular activities
FPK02_RS19210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FPK02_RS19235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPK02_RS19245	COG0121	glutamine amidotransferase
FPK02_RS19250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FPK02_RS19300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FPK02_RS19325	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPK02_RS19340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FPK02_RS19350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPK02_RS19385	COG1063	alcohol dehydrogenase
FPK02_RS19390	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FPK02_RS19390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FPK02_RS19395	COG0477	Major facilitator Superfamily
FPK02_RS19400	COG2226	methyltransferase
FPK02_RS19410	COG1793	dna ligase
FPK02_RS19460	COG2072	flavoprotein involved in K transport
FPK02_RS19470	COG0640	Transcriptional regulator
FPK02_RS19515	COG0590	tRNA wobble adenosine to inosine editing
FPK02_RS19525	COG0287	Prephenate dehydrogenase
FPK02_RS19545	COG0517	IMP dehydrogenase activity
FPK02_RS19545	COG1125	glycine betaine transport
FPK02_RS19555	COG5416	Lipopolysaccharide assembly protein A domain
FPK02_RS19565	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FPK02_RS19575	COG2205	protein histidine kinase activity
FPK02_RS19580	COG0745	RESPONSE REGULATOR receiver
FPK02_RS19585	COG0739	heme binding
FPK02_RS19615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPK02_RS19680	COG1088	dTDP-glucose 4,6-dehydratase activity
FPK02_RS19725	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FPK02_RS19740	COG1234	tRNA 3'-trailer cleavage
FPK02_RS19745	COG1960	acyl-CoA dehydrogenase activity
FPK02_RS19755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPK02_RS19760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPK02_RS19760	COG3321	synthase
FPK02_RS19760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FPK02_RS19765	COG0318	PFAM AMP-dependent synthetase and ligase
FPK02_RS19770	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FPK02_RS19785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FPK02_RS19800	COG1216	Glycosyl transferase, family 2
FPK02_RS19820	COG0657	acetylesterase activity
FPK02_RS19830	COG0561	phosphatase activity
FPK02_RS19865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FPK02_RS19875	COG5651	PPE family
FPK02_RS19880	COG2409	Drug exporters of the RND superfamily
FPK02_RS19880	COG1511	domain protein
FPK02_RS19890	COG1028	Short-chain dehydrogenase reductase Sdr
FPK02_RS19890	COG0604	alcohol dehydrogenase
FPK02_RS19890	COG3321	synthase
FPK02_RS19930	COG2207	Transcriptional regulator
FPK02_RS19970	COG1316	TRANSCRIPTIONal
FPK02_RS20020	COG2119	membrane
FPK02_RS20060	COG1796	DNA polymerase
FPK02_RS20060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPK02_RS20075	COG0070	glutamate synthase
FPK02_RS20075	COG0067	glutamate synthase
FPK02_RS20075	COG0069	glutamate synthase activity
FPK02_RS20175	COG4932	domain protein
FPK02_RS20195	COG1404	Belongs to the peptidase S8 family
FPK02_RS20200	COG0464	growth
FPK02_RS20210	COG1404	Belongs to the peptidase S8 family
FPK02_RS20240	COG5651	PPE family
FPK02_RS20250	COG1674	ftsk spoiiie
FPK02_RS20335	COG1595	DNA-templated transcription, initiation
FPK02_RS20355	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPK02_RS20355	COG3409	Peptidoglycan-binding domain 1 protein
FPK02_RS20370	COG1192	Involved in chromosome partitioning
FPK02_RS20390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPK02_RS20400	COG0230	Belongs to the bacterial ribosomal protein bL34 family