locus-tag	class	description
J112_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J112_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
J112_RS00090	COG0515	serine threonine protein kinase
J112_RS00115	COG1716	ATPase activity
J112_RS00185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J112_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS00270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J112_RS00340	COG0277	FAD linked oxidase domain protein
J112_RS00365	COG1309	transcriptional regulator
J112_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS00385	COG3344	reverse transcriptase
J112_RS00400	COG1228	amidohydrolase
J112_RS00420	COG1309	transcriptional regulator
J112_RS00450	COG3260	NADH ubiquinone oxidoreductase 20
J112_RS00460	COG0650	Formate hydrogenlyase subunit 4
J112_RS00475	COG0651	ATP synthesis coupled electron transport
J112_RS00480	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
J112_RS00480	COG3261	NADH dehydrogenase
J112_RS00520	COG1403	HNH endonuclease
J112_RS00550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS00595	COG0657	acetylesterase activity
J112_RS00605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J112_RS00605	COG2755	lipolytic protein G-D-S-L family
J112_RS00635	COG1376	ErfK ybiS ycfS ynhG family protein
J112_RS00645	COG0028	Belongs to the TPP enzyme family
J112_RS00680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J112_RS00715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS00770	COG0038	chloride channel
J112_RS00775	COG1309	transcriptional regulator
J112_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
J112_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS00800	COG3321	synthase
J112_RS00800	COG0604	alcohol dehydrogenase
J112_RS00825	COG2365	Tyrosine phosphatase family
J112_RS00860	COG1309	transcriptional regulator
J112_RS00870	COG5651	PPE family
J112_RS00870	COG0657	acetylesterase activity
J112_RS00875	COG0277	FAD linked oxidase domain protein
J112_RS00880	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J112_RS00895	COG1802	Transcriptional regulator
J112_RS00905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J112_RS00910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J112_RS00935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J112_RS00985	COG2267	carboxylic ester hydrolase activity
J112_RS01000	COG1472	Belongs to the glycosyl hydrolase 3 family
J112_RS01010	COG4122	O-methyltransferase activity
J112_RS01025	COG1937	Protein conserved in bacteria
J112_RS01030	COG2814	Major facilitator Superfamily
J112_RS01035	COG1376	ErfK ybiS ycfS ynhG family protein
J112_RS01045	COG1132	(ABC) transporter
J112_RS01060	COG0243	molybdopterin cofactor binding
J112_RS01065	COG3590	peptidase
J112_RS01105	COG2409	Drug exporters of the RND superfamily
J112_RS01160	COG0657	acetylesterase activity
J112_RS01165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J112_RS01175	COG0657	acetylesterase activity
J112_RS01185	COG1024	Enoyl-CoA hydratase
J112_RS01195	COG0500	methyltransferase
J112_RS01200	COG0297	glycogen (starch) synthase activity
J112_RS01220	COG1487	ribonuclease activity
J112_RS01260	COG4981	capsule polysaccharide biosynthetic process
J112_RS01270	COG1472	Belongs to the glycosyl hydrolase 3 family
J112_RS01290	COG2030	dehydratase
J112_RS01300	COG0183	Belongs to the thiolase family
J112_RS01305	COG1960	acyl-CoA dehydrogenase activity
J112_RS01325	COG1053	succinate dehydrogenase
J112_RS01345	COG2146	nitrite reductase [NAD(P)H] activity
J112_RS01345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J112_RS01365	COG5651	PPE family
J112_RS01400	COG1984	allophanate hydrolase subunit 2
J112_RS01420	COG2223	nitrite transmembrane transporter activity
J112_RS01425	COG2161	toxin-antitoxin pair type II binding
J112_RS01435	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS01440	COG1960	acyl-CoA dehydrogenase activity
J112_RS01455	COG0346	lactoylglutathione lyase activity
J112_RS01495	COG5651	PPE family
J112_RS01550	COG1404	Belongs to the peptidase S8 family
J112_RS01575	COG1368	sulfuric ester hydrolase activity
J112_RS01585	COG3391	amine dehydrogenase activity
J112_RS01625	COG0778	Nitroreductase
J112_RS01635	COG0671	phosphoesterase, PA-phosphatase related
J112_RS01705	COG0717	Belongs to the dCTP deaminase family
J112_RS01710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J112_RS01715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J112_RS01725	COG2226	methyltransferase
J112_RS01740	COG2226	methyltransferase
J112_RS01750	COG1252	NADH dehydrogenase
J112_RS01860	COG0789	Transcriptional regulator
J112_RS01885	COG1994	Peptidase M50
J112_RS01900	COG2239	Acts as a magnesium transporter
J112_RS01945	COG0746	molybdenum cofactor guanylyltransferase activity
J112_RS01985	COG3360	Dodecin
J112_RS02030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J112_RS02045	COG1252	NADH dehydrogenase
J112_RS02050	COG1403	HNH endonuclease
J112_RS02090	COG1960	acyl-CoA dehydrogenase activity
J112_RS02115	COG0604	alcohol dehydrogenase
J112_RS02115	COG3321	synthase
J112_RS02115	COG0604	alcohol dehydrogenase
J112_RS02115	COG3321	synthase
J112_RS02120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J112_RS02145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J112_RS02180	COG2234	aminopeptidase activity
J112_RS02215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J112_RS02270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J112_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS02315	COG5343	regulation of RNA biosynthetic process
J112_RS02330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS02375	COG1024	Enoyl-CoA hydratase
J112_RS02380	COG2337	Toxic component of a toxin-antitoxin (TA) module
J112_RS02390	COG1505	serine-type exopeptidase activity
J112_RS02450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS02475	COG2733	membrane
J112_RS02680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J112_RS02680	COG1648	precorrin-2 dehydrogenase activity
J112_RS02705	COG1366	Belongs to the anti-sigma-factor antagonist family
J112_RS02710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J112_RS02710	COG2755	lipolytic protein G-D-S-L family
J112_RS02715	COG2755	lipolytic protein G-D-S-L family
J112_RS02735	COG1113	amino acid transport
J112_RS02750	COG0406	alpha-ribazole phosphatase activity
J112_RS02760	COG0785	Cytochrome C biogenesis protein
J112_RS02770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J112_RS02805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J112_RS02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J112_RS02865	COG4221	oxidoreductase activity
J112_RS02885	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS02890	COG1228	amidohydrolase
J112_RS02940	COG0142	geranyltranstransferase activity
J112_RS02955	COG2072	flavoprotein involved in K transport
J112_RS02970	COG2345	Transcriptional regulator
J112_RS02985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J112_RS03045	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
J112_RS03055	COG3537	Alpha-1,2-mannosidase
J112_RS03075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J112_RS03100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J112_RS03110	COG1487	ribonuclease activity
J112_RS03130	COG2002	toxin-antitoxin pair type II binding
J112_RS03140	COG2972	Histidine kinase
J112_RS03145	COG0745	RESPONSE REGULATOR receiver
J112_RS03210	COG0653	protein targeting
J112_RS03285	COG1487	ribonuclease activity
J112_RS03300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J112_RS03345	COG2030	dehydratase
J112_RS03375	COG0081	regulation of translation
J112_RS03380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS03385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS03390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS03395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS03440	COG1309	transcriptional regulator
J112_RS03515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J112_RS03540	COG1960	acyl-CoA dehydrogenase activity
J112_RS03555	COG1024	Enoyl-CoA hydratase
J112_RS03570	COG1510	regulation of RNA biosynthetic process
J112_RS03585	COG1309	transcriptional regulator
J112_RS03645	COG0535	radical SAM domain protein
J112_RS03750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J112_RS03805	COG0200	Binds to the 23S rRNA
J112_RS03810	COG0616	signal peptide processing
J112_RS03825	COG0235	Class ii aldolase
J112_RS03905	COG0657	acetylesterase activity
J112_RS03985	COG0406	alpha-ribazole phosphatase activity
J112_RS04010	COG0745	RESPONSE REGULATOR receiver
J112_RS04015	COG2205	protein histidine kinase activity
J112_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS04110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J112_RS04140	COG0477	Major facilitator Superfamily
J112_RS04165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J112_RS04185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS04190	COG2188	Transcriptional regulator
J112_RS04195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J112_RS04200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J112_RS04205	COG2963	transposase activity
J112_RS04210	COG2801	Transposase and inactivated derivatives
J112_RS04220	COG3547	Transposase (IS116 IS110 IS902 family)
J112_RS04230	COG2837	iron assimilation
J112_RS04280	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J112_RS04330	COG0745	RESPONSE REGULATOR receiver
J112_RS04375	COG0640	Transcriptional regulator
J112_RS04380	COG0590	tRNA wobble adenosine to inosine editing
J112_RS04455	COG4106	trans-aconitate 2-methyltransferase activity
J112_RS04460	COG0596	Alpha beta hydrolase
J112_RS04475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J112_RS04485	COG4585	Histidine kinase
J112_RS04490	COG2132	Multicopper oxidase
J112_RS04500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J112_RS04535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J112_RS04560	COG1024	Enoyl-CoA hydratase
J112_RS04560	COG1250	3-hydroxyacyl-CoA dehydrogenase
J112_RS04585	COG0521	Mo-molybdopterin cofactor biosynthetic process
J112_RS04610	COG3304	Inner membrane component domain
J112_RS04615	COG1278	Cold shock
J112_RS04840	COG0183	Belongs to the thiolase family
J112_RS04880	COG3328	transposase activity
J112_RS05000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J112_RS05030	COG0739	heme binding
J112_RS05035	COG0045	succinate-CoA ligase (ADP-forming) activity
J112_RS05140	COG1024	Enoyl-CoA hydratase
J112_RS05155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J112_RS05170	COG0657	acetylesterase activity
J112_RS05175	COG3391	amine dehydrogenase activity
J112_RS05190	COG3391	amine dehydrogenase activity
J112_RS05195	COG0745	RESPONSE REGULATOR receiver
J112_RS05205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J112_RS05210	COG0315	cyclic pyranopterin monophosphate synthase activity
J112_RS05210	COG0521	Mo-molybdopterin cofactor biosynthetic process
J112_RS05215	COG1970	mechanosensitive ion channel activity
J112_RS05225	COG0577	efflux transmembrane transporter activity
J112_RS05235	COG0142	geranyltranstransferase activity
J112_RS05250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J112_RS05255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J112_RS05290	COG4106	trans-aconitate 2-methyltransferase activity
J112_RS05295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J112_RS05295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J112_RS05330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J112_RS05345	COG0084	hydrolase, TatD family'
J112_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS05415	COG3956	TIGRFAM MazG family protein
J112_RS05480	COG2205	protein histidine kinase activity
J112_RS05485	COG0745	RESPONSE REGULATOR receiver
J112_RS05520	COG0657	acetylesterase activity
J112_RS05540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J112_RS05565	COG3328	transposase activity
J112_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS05630	COG3391	amine dehydrogenase activity
J112_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS05715	COG0183	Belongs to the thiolase family
J112_RS05720	COG2755	lipolytic protein G-D-S-L family
J112_RS05725	COG0657	acetylesterase activity
J112_RS05765	COG1331	Highly conserved protein containing a thioredoxin domain
J112_RS05790	COG0657	acetylesterase activity
J112_RS05835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J112_RS05880	COG2272	Belongs to the type-B carboxylesterase lipase family
J112_RS05920	COG0012	GTP binding
J112_RS05975	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J112_RS05985	COG0596	Alpha beta hydrolase
J112_RS06000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J112_RS06000	COG0574	Belongs to the PEP-utilizing enzyme family
J112_RS06010	COG3800	Transcriptional regulator
J112_RS06010	COG1396	sequence-specific DNA binding
J112_RS06045	COG0183	Belongs to the thiolase family
J112_RS06065	COG1755	Isoprenylcysteine carboxyl methyltransferase
J112_RS06075	COG1024	Enoyl-CoA hydratase
J112_RS06080	COG1024	Enoyl-CoA hydratase
J112_RS06085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J112_RS06095	COG2409	Drug exporters of the RND superfamily
J112_RS06140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J112_RS06150	COG3467	pyridoxamine 5'-phosphate
J112_RS06195	COG1140	nitrate reductase beta subunit
J112_RS06210	COG1217	gtp-binding protein TYPA
J112_RS06260	COG0446	pyridine nucleotide-disulphide oxidoreductase
J112_RS06260	COG1902	pentaerythritol trinitrate reductase activity
J112_RS06270	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J112_RS06285	COG0604	alcohol dehydrogenase
J112_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS06285	COG3321	synthase
J112_RS06300	COG5651	PPE family
J112_RS06310	COG2508	Transcriptional regulator
J112_RS06310	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J112_RS06315	COG1012	belongs to the aldehyde dehydrogenase family
J112_RS06320	COG0506	proline dehydrogenase activity
J112_RS06330	COG0596	Alpha beta hydrolase
J112_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS06355	COG0657	acetylesterase activity
J112_RS06360	COG5651	PPE family
J112_RS06365	COG4842	Belongs to the WXG100 family
J112_RS06375	COG3328	transposase activity
J112_RS06380	COG0477	Major facilitator Superfamily
J112_RS06405	COG1611	Belongs to the LOG family
J112_RS06410	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS06435	COG0519	Catalyzes the synthesis of GMP from XMP
J112_RS06470	COG3559	Exporter of polyketide antibiotics
J112_RS06475	COG1131	(ABC) transporter
J112_RS06480	COG1309	transcriptional regulator
J112_RS06495	COG5662	AntiSigma factor
J112_RS06500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J112_RS06545	COG2239	Acts as a magnesium transporter
J112_RS06580	COG0598	Magnesium transport protein CorA
J112_RS06615	COG2026	Addiction module toxin, RelE StbE family
J112_RS06620	COG2161	toxin-antitoxin pair type II binding
J112_RS06625	COG0508	dehydrogenase complex catalyzes the overall conversion of
J112_RS06625	COG0567	Dehydrogenase, E1 component
J112_RS06670	COG0277	FAD linked oxidase domain protein
J112_RS07040	COG0346	lactoylglutathione lyase activity
J112_RS07075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J112_RS07085	COG0058	SHG alpha-glucan phosphorylase activity
J112_RS07135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J112_RS07260	COG5651	PPE family
J112_RS07305	COG2801	Transposase and inactivated derivatives
J112_RS07310	COG2963	transposase activity
J112_RS07345	COG2226	methyltransferase
J112_RS07425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J112_RS07430	COG2072	flavoprotein involved in K transport
J112_RS07465	COG0657	acetylesterase activity
J112_RS07580	COG1481	regulation of sporulation
J112_RS07595	COG0657	acetylesterase activity
J112_RS07600	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS07615	COG5651	PPE family
J112_RS07615	COG3391	amine dehydrogenase activity
J112_RS07630	COG1376	ErfK ybiS ycfS ynhG family protein
J112_RS07655	COG0149	triose-phosphate isomerase activity
J112_RS07675	COG0657	acetylesterase activity
J112_RS07730	COG0657	acetylesterase activity
J112_RS07740	COG0657	acetylesterase activity
J112_RS07770	COG1131	(ABC) transporter
J112_RS07795	COG0396	ATPase activity
J112_RS07810	COG2151	metal-sulfur cluster biosynthetic enzyme
J112_RS07815	COG1960	acyl-CoA dehydrogenase activity
J112_RS07835	COG3118	belongs to the thioredoxin family
J112_RS07845	COG0488	(ABC) transporter
J112_RS07855	COG1309	transcriptional regulator
J112_RS07860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J112_RS07870	COG3883	PFAM NLP P60 protein
J112_RS07870	COG0791	NLP P60 protein
J112_RS07880	COG0714	Associated with various cellular activities
J112_RS07890	COG2304	oxidoreductase activity
J112_RS07975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J112_RS07980	COG2226	methyltransferase
J112_RS07985	COG3360	Dodecin
J112_RS08015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J112_RS08025	COG4106	trans-aconitate 2-methyltransferase activity
J112_RS08045	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J112_RS08060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J112_RS08065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J112_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS08140	COG0604	alcohol dehydrogenase
J112_RS08140	COG3321	synthase
J112_RS08170	COG2070	2-Nitropropane dioxygenase
J112_RS08225	COG0300	oxidoreductase activity
J112_RS08335	COG0791	NLP P60 protein
J112_RS08335	COG3883	PFAM NLP P60 protein
J112_RS08525	COG0483	inositol monophosphate 1-phosphatase activity
J112_RS08530	COG0107	imidazoleglycerol-phosphate synthase activity
J112_RS08540	COG0387	Pfam Sodium calcium exchanger
J112_RS08595	COG1946	Acyl-CoA thioesterase
J112_RS08600	COG0456	acetyltransferase
J112_RS08600	COG0454	-acetyltransferase
J112_RS08605	COG1132	(ABC) transporter
J112_RS08610	COG4988	ABC transporter
J112_RS08615	COG1294	oxidase, subunit
J112_RS08620	COG1271	oxidase subunit
J112_RS08695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J112_RS08715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J112_RS08715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J112_RS08745	COG0657	acetylesterase activity
J112_RS08770	COG3391	amine dehydrogenase activity
J112_RS08820	COG3321	synthase
J112_RS08820	COG0604	alcohol dehydrogenase
J112_RS08825	COG3321	synthase
J112_RS08825	COG0604	alcohol dehydrogenase
J112_RS08830	COG0604	alcohol dehydrogenase
J112_RS08830	COG3321	synthase
J112_RS08830	COG4221	oxidoreductase activity
J112_RS08830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS08835	COG0604	alcohol dehydrogenase
J112_RS08835	COG0604	alcohol dehydrogenase
J112_RS08835	COG3321	synthase
J112_RS08835	COG3321	synthase
J112_RS08850	COG0488	(ABC) transporter
J112_RS08905	COG1960	acyl-CoA dehydrogenase activity
J112_RS08910	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
J112_RS08930	COG2835	tetraacyldisaccharide 4'-kinase activity
J112_RS08970	COG0647	UMP catabolic process
J112_RS09010	COG0494	nUDIX hydrolase
J112_RS09025	COG4122	O-methyltransferase activity
J112_RS09030	COG1113	amino acid transport
J112_RS09035	COG5651	PPE family
J112_RS09050	COG0659	secondary active sulfate transmembrane transporter activity
J112_RS09060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J112_RS09065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J112_RS09105	COG3246	L-lysine catabolic process to acetate
J112_RS09255	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J112_RS09265	COG1131	(ABC) transporter
J112_RS09265	COG1716	ATPase activity
J112_RS09265	COG0842	Transport permease protein
J112_RS09280	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS09295	COG5651	PPE family
J112_RS09295	COG5263	repeat protein
J112_RS09310	COG2801	Transposase and inactivated derivatives
J112_RS09315	COG2963	transposase activity
J112_RS09345	COG2963	transposase activity
J112_RS09350	COG2801	Transposase and inactivated derivatives
J112_RS09365	COG1937	Protein conserved in bacteria
J112_RS09465	COG5651	PPE family
J112_RS09475	COG5651	PPE family
J112_RS09480	COG5651	PPE family
J112_RS09510	COG1404	Belongs to the peptidase S8 family
J112_RS09530	COG5651	PPE family
J112_RS09545	COG0657	acetylesterase activity
J112_RS09560	COG0657	acetylesterase activity
J112_RS09585	COG1285	pathogenesis
J112_RS09660	COG0509	glycine decarboxylation via glycine cleavage system
J112_RS09690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J112_RS09690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J112_RS09735	COG1253	flavin adenine dinucleotide binding
J112_RS09740	COG1253	flavin adenine dinucleotide binding
J112_RS09750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J112_RS09785	COG0830	nickel cation binding
J112_RS09805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS09855	COG4221	oxidoreductase activity
J112_RS09860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J112_RS09865	COG0183	Belongs to the thiolase family
J112_RS09920	COG0174	glutamine synthetase
J112_RS09940	COG0300	oxidoreductase activity
J112_RS09960	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J112_RS10000	COG2070	2-Nitropropane dioxygenase
J112_RS10005	COG1063	alcohol dehydrogenase
J112_RS10015	COG1490	D-aminoacyl-tRNA deacylase activity
J112_RS10045	COG1950	PFAM Membrane protein of
J112_RS10050	COG1366	Belongs to the anti-sigma-factor antagonist family
J112_RS10070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J112_RS10105	COG2224	Isocitrate lyase
J112_RS10120	COG5651	PPE family
J112_RS10120	COG5263	repeat protein
J112_RS10140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J112_RS10145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J112_RS10155	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS10185	COG4977	sequence-specific DNA binding
J112_RS10195	COG1960	acyl-CoA dehydrogenase activity
J112_RS10200	COG1960	acyl-CoA dehydrogenase activity
J112_RS10205	COG1024	Enoyl-CoA hydratase
J112_RS10215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J112_RS10215	COG0543	2 iron, 2 sulfur cluster binding
J112_RS10220	COG0596	Alpha beta hydrolase
J112_RS10230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J112_RS10230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J112_RS10235	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS10240	COG2337	Toxic component of a toxin-antitoxin (TA) module
J112_RS10250	COG0653	protein targeting
J112_RS10295	COG4691	Plasmid stability protein
J112_RS10355	COG1309	transcriptional regulator
J112_RS10395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J112_RS10475	COG1872	DUF167
J112_RS10515	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS10665	COG2442	InterPro IPR007367
J112_RS10680	COG1396	sequence-specific DNA binding
J112_RS10685	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
J112_RS10750	COG0640	Transcriptional regulator
J112_RS10765	COG1752	Esterase of the alpha-beta hydrolase superfamily
J112_RS10770	COG3842	ATPase activity
J112_RS10775	COG0395	ABC-type sugar transport system, permease component
J112_RS10780	COG1175	transmembrane transport
J112_RS10795	COG1335	isochorismatase
J112_RS10820	COG3321	synthase
J112_RS10820	COG0604	alcohol dehydrogenase
J112_RS10880	COG0803	Belongs to the bacterial solute-binding protein 9 family
J112_RS10905	COG2337	Toxic component of a toxin-antitoxin (TA) module
J112_RS10930	COG2367	Beta-lactamase
J112_RS10955	COG0300	oxidoreductase activity
J112_RS11035	COG2801	Transposase and inactivated derivatives
J112_RS11110	COG4279	zinc finger
J112_RS11115	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
J112_RS11125	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
J112_RS11130	COG2963	transposase activity
J112_RS11135	COG2801	Transposase and inactivated derivatives
J112_RS11220	COG5651	PPE family
J112_RS11225	COG5651	PPE family
J112_RS11230	COG1410	methionine synthase
J112_RS11230	COG0646	methionine synthase
J112_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS11315	COG0167	dihydroorotate dehydrogenase activity
J112_RS11325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J112_RS11380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J112_RS11455	COG0768	penicillin binding
J112_RS11475	COG2801	Transposase and inactivated derivatives
J112_RS11480	COG2963	transposase activity
J112_RS11505	COG0142	geranyltranstransferase activity
J112_RS11535	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J112_RS11565	COG0003	Pfam Anion-transporting ATPase
J112_RS11580	COG1022	Amp-dependent synthetase and ligase
J112_RS11665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J112_RS11695	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J112_RS11720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J112_RS11740	COG0321	lipoyl(octanoyl) transferase activity
J112_RS11825	COG3744	PilT protein domain protein
J112_RS11990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J112_RS12065	COG0584	glycerophosphoryl diester phosphodiesterase
J112_RS12070	COG2963	transposase activity
J112_RS12075	COG2801	Transposase and inactivated derivatives
J112_RS12100	COG0657	acetylesterase activity
J112_RS12235	COG2442	InterPro IPR007367
J112_RS12295	COG0395	ABC-type sugar transport system, permease component
J112_RS12315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J112_RS12320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J112_RS12325	COG1834	amidinotransferase
J112_RS12330	COG1522	sequence-specific DNA binding
J112_RS12360	COG2223	nitrite transmembrane transporter activity
J112_RS12395	COG1045	serine acetyltransferase
J112_RS12410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J112_RS12495	COG2963	transposase activity
J112_RS12500	COG2801	Transposase and inactivated derivatives
J112_RS12575	COG0657	acetylesterase activity
J112_RS12590	COG1420	regulation of RNA biosynthetic process
J112_RS12620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS12635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J112_RS12635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS12640	COG1021	2,3-dihydroxybenzoate-AMP ligase
J112_RS12700	COG1297	OPT oligopeptide transporter protein
J112_RS12725	COG4208	sulfate ABC transporter
J112_RS12735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J112_RS12750	COG3387	PFAM Glycoside hydrolase 15-related
J112_RS12775	COG1234	tRNA 3'-trailer cleavage
J112_RS12785	COG1305	Transglutaminase-like
J112_RS12815	COG1555	photosystem II stabilization
J112_RS12815	COG1596	polysaccharide export
J112_RS12830	COG2755	lipolytic protein G-D-S-L family
J112_RS12840	COG0799	negative regulation of ribosome biogenesis
J112_RS12845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J112_RS12880	COG0542	response to heat
J112_RS12910	COG5651	PPE family
J112_RS12935	COG5002	protein histidine kinase activity
J112_RS12940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J112_RS12975	COG1301	dicarboxylic acid transport
J112_RS12980	COG1530	ribonuclease E activity
J112_RS12995	COG0285	dihydrofolate synthase activity
J112_RS13005	COG3268	Saccharopine dehydrogenase
J112_RS13010	COG1388	LysM domain
J112_RS13030	COG1013	pyruvate-flavodoxin oxidoreductase activity
J112_RS13035	COG0674	pyruvate-flavodoxin oxidoreductase activity
J112_RS13035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J112_RS13045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J112_RS13050	COG2040	homocysteine
J112_RS13070	COG0544	peptidyl-prolyl cis-trans isomerase activity
J112_RS13085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J112_RS13100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J112_RS13130	COG0366	Alpha amylase catalytic
J112_RS13150	COG0824	Thioesterase
J112_RS13155	COG2902	Dehydrogenase
J112_RS13170	COG2801	Transposase and inactivated derivatives
J112_RS13175	COG2963	transposase activity
J112_RS13200	COG0657	acetylesterase activity
J112_RS13215	COG0657	acetylesterase activity
J112_RS13255	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
J112_RS13260	COG0508	dehydrogenase complex catalyzes the overall conversion of
J112_RS13280	COG2030	dehydratase
J112_RS13285	COG1960	acyl-CoA dehydrogenase activity
J112_RS13295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J112_RS13310	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS13330	COG0300	oxidoreductase activity
J112_RS13335	COG0433	COG0433 Predicted ATPase
J112_RS13350	COG3328	transposase activity
J112_RS13390	COG1376	ErfK ybiS ycfS ynhG family protein
J112_RS13430	COG3757	hydrolase, family 25
J112_RS13445	COG1715	Restriction endonuclease
J112_RS13475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J112_RS13535	COG1487	ribonuclease activity
J112_RS13575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J112_RS13585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J112_RS13590	COG0432	Pfam Uncharacterised protein family UPF0047
J112_RS13700	COG0596	Alpha beta hydrolase
J112_RS13735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J112_RS13755	COG3320	Male sterility
J112_RS13755	COG1022	Amp-dependent synthetase and ligase
J112_RS13835	COG1946	Acyl-CoA thioesterase
J112_RS13890	COG3391	amine dehydrogenase activity
J112_RS13895	COG4762	Protein conserved in bacteria
J112_RS14010	COG1366	Belongs to the anti-sigma-factor antagonist family
J112_RS14030	COG0640	Transcriptional regulator
J112_RS14035	COG0798	PFAM Bile acid sodium symporter
J112_RS14070	COG4974	Belongs to the 'phage' integrase family
J112_RS14080	COG2963	transposase activity
J112_RS14085	COG2801	Transposase and inactivated derivatives
J112_RS14170	COG3328	transposase activity
J112_RS14210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J112_RS14290	COG0531	amino acid
J112_RS14295	COG0569	domain protein
J112_RS14435	COG1388	LysM domain
J112_RS14440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J112_RS14460	COG1960	acyl-CoA dehydrogenase activity
J112_RS14465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J112_RS14495	COG1196	nuclear chromosome segregation
J112_RS14540	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
J112_RS14545	COG3391	amine dehydrogenase activity
J112_RS14560	COG1842	Phage shock protein A
J112_RS14575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J112_RS14620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J112_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS14705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J112_RS14735	COG1522	sequence-specific DNA binding
J112_RS14740	COG0686	Belongs to the AlaDH PNT family
J112_RS14785	COG1960	acyl-CoA dehydrogenase activity
J112_RS14790	COG0183	Belongs to the thiolase family
J112_RS14810	COG2977	Belongs to the P-Pant transferase superfamily
J112_RS14815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J112_RS14845	COG2337	Toxic component of a toxin-antitoxin (TA) module
J112_RS14850	COG3609	addiction module antidote protein, CC2985 family
J112_RS14915	COG2801	Transposase and inactivated derivatives
J112_RS14920	COG2963	transposase activity
J112_RS14960	COG1353	crispr-associated protein
J112_RS14995	COG3744	PilT protein domain protein
J112_RS15000	COG4118	positive regulation of growth
J112_RS15010	COG3842	ATPase activity
J112_RS15015	COG1653	transport
J112_RS15020	COG0395	ABC-type sugar transport system, permease component
J112_RS15035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J112_RS15085	COG1648	precorrin-2 dehydrogenase activity
J112_RS15085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J112_RS15130	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
J112_RS15155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J112_RS15190	COG2161	toxin-antitoxin pair type II binding
J112_RS15195	COG2026	Addiction module toxin, RelE StbE family
J112_RS15275	COG0233	cytoplasmic translational termination
J112_RS15285	COG0745	RESPONSE REGULATOR receiver
J112_RS15310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J112_RS15415	COG1686	Belongs to the peptidase S11 family
J112_RS15450	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J112_RS15530	COG0604	alcohol dehydrogenase
J112_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS15530	COG3321	synthase
J112_RS15600	COG3321	synthase
J112_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS15660	COG1819	glycosyl
J112_RS15685	COG0701	Predicted permease
J112_RS15705	COG0742	ribosomal rna small subunit methyltransferase
J112_RS15710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J112_RS15725	COG0657	acetylesterase activity
J112_RS15730	COG0656	L-ascorbic acid biosynthetic process
J112_RS15750	COG1461	Dihydroxyacetone kinase
J112_RS15820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J112_RS15850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J112_RS15855	COG0179	Fumarylacetoacetate (FAA) hydrolase
J112_RS15860	COG2271	Major facilitator Superfamily
J112_RS15885	COG2972	Histidine kinase
J112_RS15895	COG0390	transport system, permease component
J112_RS15920	COG2259	Doxx family
J112_RS16015	COG3328	transposase activity
J112_RS16075	COG0110	maltose O-acetyltransferase activity
J112_RS16080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J112_RS16110	COG1119	ATPase activity
J112_RS16115	COG0560	Phosphoserine phosphatase
J112_RS16115	COG3830	Belongs to the UPF0237 family
J112_RS16160	COG1309	transcriptional regulator
J112_RS16210	COG2186	Transcriptional regulator
J112_RS16215	COG1960	acyl-CoA dehydrogenase activity
J112_RS16225	COG1966	Carbon starvation protein
J112_RS16310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS16375	COG2354	Protein conserved in bacteria
J112_RS16400	COG0657	acetylesterase activity
J112_RS16410	COG2337	Toxic component of a toxin-antitoxin (TA) module
J112_RS16425	COG2177	Part of the ABC transporter FtsEX involved in
J112_RS16430	COG2884	Cell division ATP-binding protein ftsE
J112_RS16440	COG0668	transmembrane transport
J112_RS16455	COG0277	FAD linked oxidase domain protein
J112_RS16475	COG2154	pterin-4-alpha-carbinolamine dehydratase
J112_RS16485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J112_RS16500	COG3328	transposase activity
J112_RS16545	COG3629	intracellular signal transduction
J112_RS16570	COG2801	Transposase and inactivated derivatives
J112_RS16605	COG5651	PPE family
J112_RS16620	COG0483	inositol monophosphate 1-phosphatase activity
J112_RS16635	COG1960	acyl-CoA dehydrogenase activity
J112_RS16640	COG0604	alcohol dehydrogenase
J112_RS16640	COG3321	synthase
J112_RS16640	COG4221	oxidoreductase activity
J112_RS16640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS16700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J112_RS16755	COG0714	Associated with various cellular activities
J112_RS16800	COG1309	transcriptional regulator
J112_RS16810	COG0154	amidase activity
J112_RS16825	COG0748	coenzyme F420 binding
J112_RS16850	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
J112_RS16855	COG1396	sequence-specific DNA binding
J112_RS16860	COG2963	transposase activity
J112_RS16865	COG2801	Transposase and inactivated derivatives
J112_RS16870	COG2963	transposase activity
J112_RS16875	COG2801	Transposase and inactivated derivatives
J112_RS16905	COG2826	transposase and inactivated derivatives, IS30 family
J112_RS16925	COG1615	UPF0182 protein
J112_RS16950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J112_RS16970	COG2816	NAD+ diphosphatase activity
J112_RS16980	COG0210	DNA helicase
J112_RS16995	COG0596	Alpha beta hydrolase
J112_RS17000	COG3695	enzyme binding
J112_RS17040	COG0513	Belongs to the DEAD box helicase family
J112_RS17055	COG0406	alpha-ribazole phosphatase activity
J112_RS17075	COG1597	lipid kinase activity
J112_RS17110	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS17120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J112_RS17135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J112_RS17140	COG1162	GTPase activity
J112_RS17160	COG2326	polyphosphate kinase activity
J112_RS17175	COG4651	solute:proton antiporter activity
J112_RS17175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J112_RS17185	COG2020	methyltransferase activity
J112_RS17200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J112_RS17255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J112_RS17260	COG0531	amino acid
J112_RS17265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J112_RS17270	COG1482	cell wall glycoprotein biosynthetic process
J112_RS17280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J112_RS17330	COG1316	TRANSCRIPTIONal
J112_RS17355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J112_RS17360	COG0659	secondary active sulfate transmembrane transporter activity
J112_RS17395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J112_RS17405	COG0424	maF-like protein
J112_RS17420	COG4770	biotin carboxylase activity
J112_RS17450	COG1522	sequence-specific DNA binding
J112_RS17460	COG1012	belongs to the aldehyde dehydrogenase family
J112_RS17470	COG1309	transcriptional regulator
J112_RS17475	COG1201	RNA secondary structure unwinding
J112_RS17490	COG3119	arylsulfatase activity
J112_RS17490	COG3408	Glycogen debranching enzyme
J112_RS17495	COG0564	pseudouridine synthase activity
J112_RS17520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
J112_RS17520	COG1473	amidohydrolase
J112_RS17535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J112_RS17545	COG3511	phospholipase C
J112_RS17580	COG2009	succinate dehydrogenase
J112_RS17590	COG1053	succinate dehydrogenase
J112_RS17595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J112_RS17630	COG2963	transposase activity
J112_RS17635	COG2801	Transposase and inactivated derivatives
J112_RS17645	COG3547	Transposase (IS116 IS110 IS902 family)
J112_RS17650	COG1595	DNA-templated transcription, initiation
J112_RS17655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J112_RS17660	COG1686	Belongs to the peptidase S11 family
J112_RS17665	COG2814	Major facilitator Superfamily
J112_RS17670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J112_RS17680	COG0789	Transcriptional regulator
J112_RS17705	COG2873	o-acetylhomoserine
J112_RS17720	COG5651	PPE family
J112_RS17740	COG5651	PPE family
J112_RS17740	COG5651	PPE family
J112_RS17775	COG0277	FAD linked oxidase domain protein
J112_RS17795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J112_RS17815	COG0842	Transport permease protein
J112_RS17815	COG1131	(ABC) transporter
J112_RS17815	COG1716	ATPase activity
J112_RS17820	COG1357	PFAM Pentapeptide repeats (8 copies)
J112_RS17835	COG2018	Roadblock/LC7 domain
J112_RS17845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J112_RS17870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS17880	COG1024	Enoyl-CoA hydratase
J112_RS17900	COG1657	PFAM Prenyltransferase squalene oxidase
J112_RS17910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J112_RS17915	COG2801	Transposase and inactivated derivatives
J112_RS17920	COG2963	transposase activity
J112_RS17930	COG0142	geranyltranstransferase activity
J112_RS17935	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
J112_RS17960	COG2030	dehydratase
J112_RS17965	COG0406	alpha-ribazole phosphatase activity
J112_RS17975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS18120	COG0456	acetyltransferase
J112_RS18155	COG1484	DNA-dependent DNA replication
J112_RS18160	COG4584	PFAM Integrase catalytic
J112_RS18175	COG2801	Transposase and inactivated derivatives
J112_RS18180	COG3328	transposase activity
J112_RS18185	COG0076	glutamate decarboxylase activity
J112_RS18245	COG4842	Belongs to the WXG100 family
J112_RS18250	COG4842	Belongs to the WXG100 family
J112_RS18260	COG1674	ftsk spoiiie
J112_RS18270	COG1404	Belongs to the peptidase S8 family
J112_RS18315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J112_RS18330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J112_RS18355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J112_RS18360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J112_RS18365	COG0028	Belongs to the TPP enzyme family
J112_RS18385	COG2963	transposase activity
J112_RS18390	COG2801	Transposase and inactivated derivatives
J112_RS18395	COG0477	Major facilitator Superfamily
J112_RS18405	COG5651	PPE family
J112_RS18410	COG1752	Esterase of the alpha-beta hydrolase superfamily
J112_RS18415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS18435	COG1316	TRANSCRIPTIONal
J112_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS18445	COG2259	Doxx family
J112_RS18450	COG0657	acetylesterase activity
J112_RS18455	COG1695	Transcriptional regulator
J112_RS18490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J112_RS18515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J112_RS18520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J112_RS18535	COG1960	acyl-CoA dehydrogenase activity
J112_RS18540	COG1960	acyl-CoA dehydrogenase activity
J112_RS18545	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS18550	COG0657	acetylesterase activity
J112_RS18620	COG1024	Enoyl-CoA hydratase
J112_RS18630	COG2124	cytochrome p450
J112_RS18640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J112_RS18650	COG0183	Belongs to the thiolase family
J112_RS18655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J112_RS18670	COG4638	Rieske (2fe-2S)
J112_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS18725	COG3971	2-oxopent-4-enoate hydratase activity
J112_RS18730	COG1053	succinate dehydrogenase
J112_RS18735	COG2030	dehydratase
J112_RS18755	COG2030	dehydratase
J112_RS18760	COG1960	acyl-CoA dehydrogenase activity
J112_RS18765	COG1960	acyl-CoA dehydrogenase activity
J112_RS18775	COG0183	Belongs to the thiolase family
J112_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS18795	COG1024	Enoyl-CoA hydratase
J112_RS18815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J112_RS18825	COG0183	Belongs to the thiolase family
J112_RS18845	COG1960	acyl-CoA dehydrogenase activity
J112_RS18850	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS18855	COG1960	acyl-CoA dehydrogenase activity
J112_RS18860	COG1960	acyl-CoA dehydrogenase activity
J112_RS18865	COG1960	acyl-CoA dehydrogenase activity
J112_RS18870	COG0436	Aminotransferase
J112_RS18915	COG1960	acyl-CoA dehydrogenase activity
J112_RS18920	COG1309	transcriptional regulator
J112_RS18925	COG1609	Transcriptional regulator
J112_RS18945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J112_RS19000	COG0657	acetylesterase activity
J112_RS19020	COG0739	heme binding
J112_RS19100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J112_RS19130	COG2267	carboxylic ester hydrolase activity
J112_RS19180	COG2027	D-alanyl-D-alanine carboxypeptidase
J112_RS19245	COG3328	transposase activity
J112_RS19250	COG2184	nucleotidyltransferase activity
J112_RS19265	COG0470	DNA polymerase III
J112_RS19290	COG1205	dead DEAH box helicase
J112_RS19290	COG1111	helicase
J112_RS19295	COG0657	acetylesterase activity
J112_RS19360	COG4172	Belongs to the ABC transporter superfamily
J112_RS19365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J112_RS19370	COG0601	transmembrane transport
J112_RS19410	COG0494	nUDIX hydrolase
J112_RS19435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J112_RS19470	COG1408	metallophosphoesterase
J112_RS19475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J112_RS19520	COG0714	Associated with various cellular activities
J112_RS19540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J112_RS19575	COG0121	glutamine amidotransferase
J112_RS19580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J112_RS19630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J112_RS19655	COG0860	N-Acetylmuramoyl-L-alanine amidase
J112_RS19670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J112_RS19680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J112_RS19705	COG1063	alcohol dehydrogenase
J112_RS19710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J112_RS19710	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
J112_RS19720	COG2226	methyltransferase
J112_RS19730	COG1793	dna ligase
J112_RS19785	COG2072	flavoprotein involved in K transport
J112_RS19795	COG0640	Transcriptional regulator
J112_RS19820	COG1569	PIN domain
J112_RS19825	COG3311	Transcriptional regulator
J112_RS19850	COG0287	Prephenate dehydrogenase
J112_RS19870	COG0517	IMP dehydrogenase activity
J112_RS19870	COG1125	glycine betaine transport
J112_RS19880	COG5416	Lipopolysaccharide assembly protein A domain
J112_RS19890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J112_RS19900	COG2205	protein histidine kinase activity
J112_RS19905	COG0745	RESPONSE REGULATOR receiver
J112_RS19910	COG0739	heme binding
J112_RS19980	COG1403	HNH endonuclease
J112_RS20035	COG1088	dTDP-glucose 4,6-dehydratase activity
J112_RS20080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J112_RS20095	COG1234	tRNA 3'-trailer cleavage
J112_RS20100	COG1960	acyl-CoA dehydrogenase activity
J112_RS20110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J112_RS20120	COG0318	PFAM AMP-dependent synthetase and ligase
J112_RS20125	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
J112_RS20140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J112_RS20155	COG1216	Glycosyl transferase, family 2
J112_RS20175	COG0657	acetylesterase activity
J112_RS20185	COG0561	phosphatase activity
J112_RS20220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J112_RS20230	COG5651	PPE family
J112_RS20235	COG1511	domain protein
J112_RS20235	COG2409	Drug exporters of the RND superfamily
J112_RS20245	COG0604	alcohol dehydrogenase
J112_RS20245	COG3321	synthase
J112_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
J112_RS20290	COG2207	Transcriptional regulator
J112_RS20325	COG1316	TRANSCRIPTIONal
J112_RS20370	COG2119	membrane
J112_RS20410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J112_RS20410	COG1796	DNA polymerase
J112_RS20425	COG0067	glutamate synthase
J112_RS20425	COG0069	glutamate synthase activity
J112_RS20425	COG0070	glutamate synthase
J112_RS20525	COG4932	domain protein
J112_RS20545	COG1404	Belongs to the peptidase S8 family
J112_RS20560	COG1404	Belongs to the peptidase S8 family
J112_RS20590	COG5651	PPE family
J112_RS20600	COG1674	ftsk spoiiie
J112_RS20685	COG1595	DNA-templated transcription, initiation
J112_RS20705	COG0860	N-Acetylmuramoyl-L-alanine amidase
J112_RS20705	COG3409	Peptidoglycan-binding domain 1 protein
J112_RS20720	COG1192	Involved in chromosome partitioning
J112_RS20740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J112_RS20750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J112_RS20800	COG3391	amine dehydrogenase activity