locus-tag	class	description
A3O05_RS00010	COG0592	DNA-directed DNA polymerase activity
A3O05_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3O05_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3O05_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
A3O05_RS00030	COG0187	DNA topoisomerase II activity
A3O05_RS00120	COG0583	DNA-binding transcription factor activity
A3O05_RS00135	COG0457	Tetratricopeptide repeat
A3O05_RS00135	COG0705	Rhomboid family
A3O05_RS00170	COG2815	serine threonine protein kinase
A3O05_RS00170	COG0515	serine threonine protein kinase
A3O05_RS00175	COG0515	serine threonine protein kinase
A3O05_RS00180	COG0768	penicillin binding
A3O05_RS00195	COG1716	ATPase activity
A3O05_RS00200	COG1716	ATPase activity
A3O05_RS00215	COG0754	glutathionylspermidine amidase activity
A3O05_RS00225	COG1309	transcriptional regulator
A3O05_RS00245	COG4842	Belongs to the WXG100 family
A3O05_RS00265	COG0590	tRNA wobble adenosine to inosine editing
A3O05_RS00275	COG0583	DNA-binding transcription factor activity
A3O05_RS00280	COG1643	Atp-dependent helicase
A3O05_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS00305	COG4585	Histidine kinase
A3O05_RS00325	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS00370	COG2072	flavoprotein involved in K transport
A3O05_RS00380	COG0346	lactoylglutathione lyase activity
A3O05_RS00385	COG1414	Transcriptional regulator
A3O05_RS00405	COG1053	succinate dehydrogenase
A3O05_RS00435	COG1785	Belongs to the alkaline phosphatase family
A3O05_RS00455	COG0067	glutamate synthase
A3O05_RS00455	COG0070	glutamate synthase
A3O05_RS00455	COG0069	glutamate synthase activity
A3O05_RS00485	COG1796	DNA polymerase
A3O05_RS00485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3O05_RS00495	COG2072	flavoprotein involved in K transport
A3O05_RS00505	COG2124	cytochrome p450
A3O05_RS00520	COG1024	Enoyl-CoA hydratase
A3O05_RS00545	COG2372	response to copper ion
A3O05_RS00595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3O05_RS00615	COG3447	MASE1 domain protein
A3O05_RS00615	COG5002	protein histidine kinase activity
A3O05_RS00615	COG5001	Diguanylate cyclase
A3O05_RS00625	COG1528	Iron-storage protein
A3O05_RS00630	COG1528	Iron-storage protein
A3O05_RS00635	COG1316	TRANSCRIPTIONal
A3O05_RS00665	COG0406	alpha-ribazole phosphatase activity
A3O05_RS00675	COG0028	Belongs to the TPP enzyme family
A3O05_RS00700	COG2072	flavoprotein involved in K transport
A3O05_RS00710	COG2072	flavoprotein involved in K transport
A3O05_RS00730	COG1285	pathogenesis
A3O05_RS00780	COG2146	nitrite reductase [NAD(P)H] activity
A3O05_RS00780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3O05_RS00790	COG4133	protoheme IX ABC transporter activity
A3O05_RS00795	COG2070	2-Nitropropane dioxygenase
A3O05_RS00800	COG1942	4-Oxalocrotonate Tautomerase
A3O05_RS00805	COG0583	DNA-binding transcription factor activity
A3O05_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS00835	COG0561	phosphatase activity
A3O05_RS00855	COG1216	Glycosyl transferase, family 2
A3O05_RS00860	COG0671	phosphoesterase, PA-phosphatase related
A3O05_RS00865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A3O05_RS00870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O05_RS00890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A3O05_RS00895	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS00900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O05_RS00900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A3O05_RS00900	COG3321	synthase
A3O05_RS00905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O05_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS00960	COG0277	FAD linked oxidase domain protein
A3O05_RS00975	COG2376	Dihydroxyacetone kinase
A3O05_RS00980	COG2267	carboxylic ester hydrolase activity
A3O05_RS00985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O05_RS00990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O05_RS01005	COG0671	phosphoesterase, PA-phosphatase related
A3O05_RS01015	COG1216	Glycosyl transferase, family 2
A3O05_RS01125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O05_RS01130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3O05_RS01200	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS01240	COG1174	glycine betaine transport
A3O05_RS01255	COG0287	Prephenate dehydrogenase
A3O05_RS01265	COG0590	tRNA wobble adenosine to inosine editing
A3O05_RS01290	COG0343	queuine tRNA-ribosyltransferase activity
A3O05_RS01310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3O05_RS01315	COG1793	dna ligase
A3O05_RS01345	COG2271	Major facilitator Superfamily
A3O05_RS01350	COG2130	NADP-dependent
A3O05_RS01375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3O05_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS01445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O05_RS01470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O05_RS01480	COG0148	phosphopyruvate hydratase activity
A3O05_RS01510	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3O05_RS01535	COG1492	cobalamin metabolic process
A3O05_RS01560	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS01575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A3O05_RS01605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3O05_RS01625	COG1231	oxidoreductase activity
A3O05_RS01655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O05_RS01665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A3O05_RS01695	COG2070	2-Nitropropane dioxygenase
A3O05_RS01735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3O05_RS01740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3O05_RS01745	COG2971	BadF BadG BcrA BcrD
A3O05_RS01750	COG2814	Major facilitator Superfamily
A3O05_RS01770	COG3572	ergothioneine biosynthetic process
A3O05_RS01775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3O05_RS01780	COG0121	glutamine amidotransferase
A3O05_RS01785	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A3O05_RS01790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O05_RS01815	COG0183	Belongs to the thiolase family
A3O05_RS01820	COG2030	dehydratase
A3O05_RS01825	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS01830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3O05_RS01840	COG1695	Transcriptional regulator
A3O05_RS01850	COG0569	domain protein
A3O05_RS01850	COG0475	glutathione-regulated potassium exporter activity
A3O05_RS01870	COG0714	Associated with various cellular activities
A3O05_RS01915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3O05_RS01920	COG1074	ATP-dependent DNA helicase activity
A3O05_RS01925	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A3O05_RS01935	COG2755	lipolytic protein G-D-S-L family
A3O05_RS01965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3O05_RS01970	COG1408	metallophosphoesterase
A3O05_RS01975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A3O05_RS02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3O05_RS02045	COG2945	thiolester hydrolase activity
A3O05_RS02045	COG0596	Alpha beta hydrolase
A3O05_RS02060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3O05_RS02065	COG0747	negative chemotaxis
A3O05_RS02075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3O05_RS02160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O05_RS02165	COG1309	transcriptional regulator
A3O05_RS02170	COG0657	acetylesterase activity
A3O05_RS02175	COG1902	pentaerythritol trinitrate reductase activity
A3O05_RS02180	COG1205	dead DEAH box helicase
A3O05_RS02180	COG1111	helicase
A3O05_RS02185	COG1278	Cold shock
A3O05_RS02195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3O05_RS02195	COG1754	DNA topoisomerase type I activity
A3O05_RS02205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3O05_RS02280	COG1215	transferase activity, transferring glycosyl groups
A3O05_RS02315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O05_RS02350	COG2027	D-alanyl-D-alanine carboxypeptidase
A3O05_RS02385	COG1063	alcohol dehydrogenase
A3O05_RS02395	COG2267	carboxylic ester hydrolase activity
A3O05_RS02405	COG1309	transcriptional regulator
A3O05_RS02420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O05_RS02465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A3O05_RS02475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A3O05_RS02495	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3O05_RS02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3O05_RS02540	COG4977	sequence-specific DNA binding
A3O05_RS02545	COG1194	a g-specific adenine glycosylase
A3O05_RS02555	COG1316	TRANSCRIPTIONal
A3O05_RS02565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A3O05_RS02575	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3O05_RS02595	COG1329	Transcriptional regulator
A3O05_RS02600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A3O05_RS02610	COG0215	cysteine-tRNA ligase activity
A3O05_RS02620	COG0584	glycerophosphoryl diester phosphodiesterase
A3O05_RS02630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3O05_RS02635	COG1120	ATPase activity
A3O05_RS02640	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3O05_RS02650	COG1309	transcriptional regulator
A3O05_RS02655	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3O05_RS02680	COG0346	lactoylglutathione lyase activity
A3O05_RS02720	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02725	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02730	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02735	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS02740	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02755	COG0183	Belongs to the thiolase family
A3O05_RS02785	COG1024	Enoyl-CoA hydratase
A3O05_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS02815	COG0183	Belongs to the thiolase family
A3O05_RS02825	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02830	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS02835	COG2030	dehydratase
A3O05_RS02860	COG2030	dehydratase
A3O05_RS02865	COG1053	succinate dehydrogenase
A3O05_RS02875	COG3971	2-oxopent-4-enoate hydratase activity
A3O05_RS02920	COG0651	ATP synthesis coupled electron transport
A3O05_RS02930	COG2111	Na H antiporter
A3O05_RS02930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3O05_RS02935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O05_RS02955	COG0647	UMP catabolic process
A3O05_RS02980	COG4221	oxidoreductase activity
A3O05_RS03000	COG0459	protein refolding
A3O05_RS03015	COG0714	Associated with various cellular activities
A3O05_RS03065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS03080	COG4842	Belongs to the WXG100 family
A3O05_RS03120	COG0745	RESPONSE REGULATOR receiver
A3O05_RS03125	COG5000	phosphorelay sensor kinase activity
A3O05_RS03125	COG5002	protein histidine kinase activity
A3O05_RS03130	COG0537	adenosine 5'-monophosphoramidase activity
A3O05_RS03135	COG0697	spore germination
A3O05_RS03145	COG0596	Alpha beta hydrolase
A3O05_RS03175	COG0436	Aminotransferase
A3O05_RS03185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3O05_RS03210	COG0477	Major facilitator Superfamily
A3O05_RS03215	COG0386	Belongs to the glutathione peroxidase family
A3O05_RS03225	COG3573	Dehydrogenase
A3O05_RS03235	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3O05_RS03255	COG1362	aminopeptidase activity
A3O05_RS03335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3O05_RS03345	COG0601	transmembrane transport
A3O05_RS03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3O05_RS03355	COG4172	Belongs to the ABC transporter superfamily
A3O05_RS03385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3O05_RS03395	COG0354	folic acid binding
A3O05_RS03445	COG2897	thiosulfate sulfurtransferase activity
A3O05_RS03465	COG0745	RESPONSE REGULATOR receiver
A3O05_RS03485	COG0581	inorganic phosphate transmembrane transporter activity
A3O05_RS03490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3O05_RS03495	COG0604	alcohol dehydrogenase
A3O05_RS03550	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3O05_RS03575	COG0697	spore germination
A3O05_RS03595	COG0442	prolyl-tRNA aminoacylation
A3O05_RS03600	COG2814	Major facilitator Superfamily
A3O05_RS03630	COG5651	PPE family
A3O05_RS03635	COG0436	Aminotransferase
A3O05_RS03655	COG0531	amino acid
A3O05_RS03660	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
A3O05_RS03665	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS03675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O05_RS03685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O05_RS03690	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS03695	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS03700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O05_RS03710	COG0657	acetylesterase activity
A3O05_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS03745	COG1024	Enoyl-CoA hydratase
A3O05_RS03790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O05_RS03795	COG0657	acetylesterase activity
A3O05_RS03815	COG0183	Belongs to the thiolase family
A3O05_RS03830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O05_RS03850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O05_RS03865	COG1061	Type III restriction enzyme res subunit
A3O05_RS03905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O05_RS03925	COG1278	Cold shock
A3O05_RS03965	COG2814	Major facilitator Superfamily
A3O05_RS04025	COG1764	response to oxidative stress
A3O05_RS04030	COG1846	Transcriptional regulator
A3O05_RS04035	COG1216	Glycosyl transferase, family 2
A3O05_RS04040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O05_RS04070	COG0259	pyridoxamine-phosphate oxidase activity
A3O05_RS04080	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS04085	COG5651	PPE family
A3O05_RS04090	COG2409	Drug exporters of the RND superfamily
A3O05_RS04115	COG4977	sequence-specific DNA binding
A3O05_RS04135	COG1846	Transcriptional regulator
A3O05_RS04150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O05_RS04155	COG0833	amino acid
A3O05_RS04170	COG2186	Transcriptional regulator
A3O05_RS04175	COG0545	Peptidyl-prolyl cis-trans isomerase
A3O05_RS04215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3O05_RS04220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O05_RS04230	COG1073	alpha beta
A3O05_RS04265	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS04280	COG3022	response to hydroperoxide
A3O05_RS04290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3O05_RS04325	COG1309	transcriptional regulator
A3O05_RS04360	COG1393	Belongs to the ArsC family
A3O05_RS04365	COG0583	DNA-binding transcription factor activity
A3O05_RS04405	COG0183	Belongs to the thiolase family
A3O05_RS04450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS04465	COG0438	transferase activity, transferring glycosyl groups
A3O05_RS04490	COG0438	transferase activity, transferring glycosyl groups
A3O05_RS04495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3O05_RS04540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
A3O05_RS04550	COG1846	Transcriptional regulator
A3O05_RS04595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A3O05_RS04605	COG2326	polyphosphate kinase activity
A3O05_RS04620	COG2084	Dehydrogenase
A3O05_RS04635	COG0523	cobalamin synthesis protein
A3O05_RS04640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3O05_RS04645	COG0235	Class ii aldolase
A3O05_RS04650	COG1396	sequence-specific DNA binding
A3O05_RS04655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3O05_RS04660	COG0166	Belongs to the GPI family
A3O05_RS04770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O05_RS04800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O05_RS04805	COG0315	cyclic pyranopterin monophosphate synthase activity
A3O05_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3O05_RS04835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3O05_RS04840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3O05_RS04945	COG2235	arginine
A3O05_RS04960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3O05_RS04975	COG1252	NADH dehydrogenase
A3O05_RS04985	COG0084	hydrolase, TatD family'
A3O05_RS04990	COG3583	domain protein
A3O05_RS05005	COG0515	serine threonine protein kinase
A3O05_RS05005	COG2815	serine threonine protein kinase
A3O05_RS05025	COG2409	Drug exporters of the RND superfamily
A3O05_RS05030	COG0456	acetyltransferase
A3O05_RS05030	COG1846	Transcriptional regulator
A3O05_RS05035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A3O05_RS05040	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS05075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A3O05_RS05085	COG1309	transcriptional regulator
A3O05_RS05125	COG1309	transcriptional regulator
A3O05_RS05170	COG3956	TIGRFAM MazG family protein
A3O05_RS05185	COG2837	iron assimilation
A3O05_RS05190	COG2822	iron ion transport
A3O05_RS05225	COG0596	Alpha beta hydrolase
A3O05_RS05250	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS05275	COG0427	acetyl-CoA hydrolase
A3O05_RS05325	COG1846	Transcriptional regulator
A3O05_RS05340	COG1024	Enoyl-CoA hydratase
A3O05_RS05370	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS05375	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS05400	COG2070	2-Nitropropane dioxygenase
A3O05_RS05405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O05_RS05415	COG1024	Enoyl-CoA hydratase
A3O05_RS05435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS05440	COG1024	Enoyl-CoA hydratase
A3O05_RS05445	COG0596	Alpha beta hydrolase
A3O05_RS05470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS05475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS05545	COG0183	Belongs to the thiolase family
A3O05_RS05550	COG2755	lipolytic protein G-D-S-L family
A3O05_RS05555	COG0657	acetylesterase activity
A3O05_RS05580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A3O05_RS05600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3O05_RS05610	COG1331	Highly conserved protein containing a thioredoxin domain
A3O05_RS05615	COG3631	Ketosteroid isomerase-related protein
A3O05_RS05630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3O05_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS05640	COG2124	cytochrome p450
A3O05_RS05660	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS05700	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O05_RS05710	COG1174	glycine betaine transport
A3O05_RS05720	COG1174	glycine betaine transport
A3O05_RS05765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A3O05_RS05775	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A3O05_RS05780	COG0726	polysaccharide deacetylase
A3O05_RS05850	COG1570	exodeoxyribonuclease VII activity
A3O05_RS05860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A3O05_RS05875	COG1966	Carbon starvation protein
A3O05_RS05900	COG3189	MarR family transcriptional regulator
A3O05_RS05905	COG0012	GTP binding
A3O05_RS05925	COG2132	Multicopper oxidase
A3O05_RS05935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3O05_RS05945	COG0488	(ABC) transporter
A3O05_RS06005	COG2409	Drug exporters of the RND superfamily
A3O05_RS06040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3O05_RS06060	COG1716	ATPase activity
A3O05_RS06090	COG1051	belongs to the nudix hydrolase family
A3O05_RS06115	COG1217	gtp-binding protein TYPA
A3O05_RS06125	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A3O05_RS06130	COG1609	Transcriptional regulator
A3O05_RS06130	COG2207	Transcriptional regulator
A3O05_RS06190	COG1902	pentaerythritol trinitrate reductase activity
A3O05_RS06190	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3O05_RS06200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A3O05_RS06210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O05_RS06215	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS06220	COG0506	proline dehydrogenase activity
A3O05_RS06225	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS06250	COG2207	Transcriptional regulator
A3O05_RS06265	COG1611	Belongs to the LOG family
A3O05_RS06270	COG1611	Belongs to the LOG family
A3O05_RS06275	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS06285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3O05_RS06295	COG0463	Glycosyl transferase, family 2
A3O05_RS06310	COG0519	Catalyzes the synthesis of GMP from XMP
A3O05_RS06320	COG0297	glycogen (starch) synthase activity
A3O05_RS06345	COG3559	Exporter of polyketide antibiotics
A3O05_RS06350	COG1131	(ABC) transporter
A3O05_RS06355	COG1309	transcriptional regulator
A3O05_RS06365	COG1595	DNA-templated transcription, initiation
A3O05_RS06370	COG5662	AntiSigma factor
A3O05_RS06375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O05_RS06445	COG0598	Magnesium transport protein CorA
A3O05_RS06450	COG2095	MarC family integral membrane protein
A3O05_RS06465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O05_RS06470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O05_RS06490	COG3835	regulator
A3O05_RS06495	COG1073	alpha beta
A3O05_RS06500	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3O05_RS06500	COG0567	Dehydrogenase, E1 component
A3O05_RS06510	COG2814	Major facilitator Superfamily
A3O05_RS06570	COG0277	FAD linked oxidase domain protein
A3O05_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS06590	COG0668	transmembrane transport
A3O05_RS06680	COG2814	Major facilitator Superfamily
A3O05_RS06710	COG0019	diaminopimelate decarboxylase activity
A3O05_RS06715	COG0460	homoserine dehydrogenase
A3O05_RS06720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3O05_RS06760	COG2890	protein-(glutamine-N5) methyltransferase activity
A3O05_RS06770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3O05_RS06780	COG0356	it plays a direct role in the translocation of protons across the membrane
A3O05_RS06785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3O05_RS06810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A3O05_RS06870	COG0346	lactoylglutathione lyase activity
A3O05_RS06875	COG0183	Belongs to the thiolase family
A3O05_RS06880	COG2409	Drug exporters of the RND superfamily
A3O05_RS06895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A3O05_RS06900	COG0366	Alpha amylase catalytic
A3O05_RS06905	COG0058	SHG alpha-glucan phosphorylase activity
A3O05_RS06920	COG1335	isochorismatase
A3O05_RS06930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3O05_RS06945	COG3191	aminopeptidase activity
A3O05_RS06990	COG0604	alcohol dehydrogenase
A3O05_RS07010	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS07025	COG0419	ATPase involved in DNA repair
A3O05_RS07030	COG1024	Enoyl-CoA hydratase
A3O05_RS07040	COG0243	molybdopterin cofactor binding
A3O05_RS07055	COG2188	Transcriptional regulator
A3O05_RS07120	COG0596	Alpha beta hydrolase
A3O05_RS07125	COG3757	hydrolase, family 25
A3O05_RS07140	COG1051	belongs to the nudix hydrolase family
A3O05_RS07175	COG1309	transcriptional regulator
A3O05_RS07190	COG4585	Histidine kinase
A3O05_RS07195	COG2197	response regulator
A3O05_RS07205	COG2239	Acts as a magnesium transporter
A3O05_RS07215	COG0300	oxidoreductase activity
A3O05_RS07225	COG0656	L-ascorbic acid biosynthetic process
A3O05_RS07240	COG1376	ErfK ybiS ycfS ynhG family protein
A3O05_RS07255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A3O05_RS07260	COG0433	COG0433 Predicted ATPase
A3O05_RS07275	COG0300	oxidoreductase activity
A3O05_RS07290	COG1301	dicarboxylic acid transport
A3O05_RS07300	COG0531	amino acid
A3O05_RS07320	COG4424	Sulfotransferase
A3O05_RS07325	COG3119	arylsulfatase activity
A3O05_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS07375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3O05_RS07375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3O05_RS07415	COG2902	Dehydrogenase
A3O05_RS07420	COG0824	Thioesterase
A3O05_RS07435	COG0366	Alpha amylase catalytic
A3O05_RS07470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3O05_RS07490	COG1309	transcriptional regulator
A3O05_RS07505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A3O05_RS07525	COG0740	serine-type endopeptidase activity
A3O05_RS07530	COG0740	serine-type endopeptidase activity
A3O05_RS07580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3O05_RS07590	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3O05_RS07590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3O05_RS07595	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3O05_RS07605	COG1388	LysM domain
A3O05_RS07635	COG0525	valine-tRNA ligase activity
A3O05_RS07640	COG0285	dihydrofolate synthase activity
A3O05_RS07655	COG1530	ribonuclease E activity
A3O05_RS07685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3O05_RS07705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3O05_RS07710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A3O05_RS07715	COG0542	response to heat
A3O05_RS07725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A3O05_RS07735	COG0406	alpha-ribazole phosphatase activity
A3O05_RS07740	COG2755	lipolytic protein G-D-S-L family
A3O05_RS07760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O05_RS07795	COG2308	Evidence 4 Homologs of previously reported genes of
A3O05_RS07805	COG1305	Transglutaminase-like
A3O05_RS07835	COG3387	PFAM Glycoside hydrolase 15-related
A3O05_RS07850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O05_RS07885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3O05_RS07890	COG4208	sulfate ABC transporter
A3O05_RS07950	COG0484	heat shock protein binding
A3O05_RS08030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3O05_RS08045	COG0076	glutamate decarboxylase activity
A3O05_RS08080	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS08085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS08130	COG0423	glycine-tRNA ligase activity
A3O05_RS08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3O05_RS08140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A3O05_RS08160	COG0358	DNA primase activity
A3O05_RS08235	COG0745	RESPONSE REGULATOR receiver
A3O05_RS08240	COG5002	protein histidine kinase activity
A3O05_RS08255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3O05_RS08285	COG2199	diguanylate cyclase activity
A3O05_RS08320	COG0488	(ABC) transporter
A3O05_RS08345	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS08350	COG1335	isochorismatase
A3O05_RS08360	COG0058	SHG alpha-glucan phosphorylase activity
A3O05_RS08400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O05_RS08405	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS08410	COG0183	Belongs to the thiolase family
A3O05_RS08430	COG1228	amidohydrolase
A3O05_RS08470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O05_RS08500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A3O05_RS08530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O05_RS08570	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A3O05_RS08575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3O05_RS08635	COG0714	Associated with various cellular activities
A3O05_RS08660	COG0557	exoribonuclease II activity
A3O05_RS08670	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS08695	COG0174	glutamine synthetase
A3O05_RS08700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A3O05_RS08730	COG2205	protein histidine kinase activity
A3O05_RS08760	COG0174	glutamine synthetase
A3O05_RS08770	COG0477	Major facilitator Superfamily
A3O05_RS08780	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A3O05_RS08800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A3O05_RS08805	COG0321	lipoyl(octanoyl) transferase activity
A3O05_RS08820	COG1872	DUF167
A3O05_RS08840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3O05_RS08850	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3O05_RS08855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3O05_RS08885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3O05_RS08930	COG2010	Cytochrome c
A3O05_RS08935	COG1845	cytochrome c oxidase, subunit III
A3O05_RS08940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A3O05_RS08975	COG2226	methyltransferase
A3O05_RS09000	COG0003	Pfam Anion-transporting ATPase
A3O05_RS09010	COG0204	Acyl-transferase
A3O05_RS09015	COG5650	phosphatidylinositol metabolic process
A3O05_RS09025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A3O05_RS09050	COG0142	geranyltranstransferase activity
A3O05_RS09090	COG0768	penicillin binding
A3O05_RS09110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3O05_RS09120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3O05_RS09135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3O05_RS09160	COG0640	Transcriptional regulator
A3O05_RS09210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O05_RS09220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O05_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS09260	COG2814	Major facilitator Superfamily
A3O05_RS09320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3O05_RS09350	COG1968	undecaprenyl-diphosphatase activity
A3O05_RS09385	COG1218	3'(2'),5'-bisphosphate nucleotidase
A3O05_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS09430	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A3O05_RS09445	COG2860	membrane
A3O05_RS09455	COG1410	methionine synthase
A3O05_RS09455	COG0646	methionine synthase
A3O05_RS09460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3O05_RS09470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3O05_RS09505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3O05_RS09510	COG1034	ATP synthesis coupled electron transport
A3O05_RS09515	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3O05_RS09520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3O05_RS09600	COG0513	Belongs to the DEAD box helicase family
A3O05_RS09640	COG0028	Belongs to the TPP enzyme family
A3O05_RS09655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3O05_RS09660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O05_RS09665	COG4122	O-methyltransferase activity
A3O05_RS09695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3O05_RS09700	COG4521	taurine ABC transporter
A3O05_RS09705	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A3O05_RS09740	COG2378	regulation of single-species biofilm formation
A3O05_RS09745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3O05_RS09780	COG0300	oxidoreductase activity
A3O05_RS09835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3O05_RS09845	COG0463	Glycosyl transferase, family 2
A3O05_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS09895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3O05_RS09905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3O05_RS09910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS09930	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A3O05_RS09940	COG1404	Belongs to the peptidase S8 family
A3O05_RS09955	COG4842	Belongs to the WXG100 family
A3O05_RS09985	COG0464	growth
A3O05_RS10005	COG0583	DNA-binding transcription factor activity
A3O05_RS10035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3O05_RS10040	COG1169	isochorismate synthase
A3O05_RS10045	COG0789	Transcriptional regulator
A3O05_RS10050	COG1021	2,3-dihydroxybenzoate-AMP ligase
A3O05_RS10080	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O05_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS10105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS10105	COG3321	synthase
A3O05_RS10105	COG0300	oxidoreductase activity
A3O05_RS10120	COG1132	(ABC) transporter
A3O05_RS10125	COG1132	(ABC) transporter
A3O05_RS10125	COG2375	cellular response to nickel ion
A3O05_RS10130	COG0477	Major facilitator Superfamily
A3O05_RS10135	COG5285	phytanoyl-CoA dioxygenase
A3O05_RS10145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O05_RS10150	COG0456	acetyltransferase
A3O05_RS10170	COG2837	iron assimilation
A3O05_RS10180	COG2186	Transcriptional regulator
A3O05_RS10185	COG2807	transmembrane transport
A3O05_RS10195	COG2409	Drug exporters of the RND superfamily
A3O05_RS10200	COG3629	intracellular signal transduction
A3O05_RS10205	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS10245	COG0475	glutathione-regulated potassium exporter activity
A3O05_RS10310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3O05_RS10310	COG0237	dephospho-CoA kinase activity
A3O05_RS10485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3O05_RS10490	COG0072	phenylalanine-tRNA ligase activity
A3O05_RS10490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3O05_RS10500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A3O05_RS10505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A3O05_RS10510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3O05_RS10515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3O05_RS10520	COG1438	arginine binding
A3O05_RS10525	COG0137	argininosuccinate synthase activity
A3O05_RS10565	COG2835	tetraacyldisaccharide 4'-kinase activity
A3O05_RS10570	COG1309	transcriptional regulator
A3O05_RS10575	COG2094	Belongs to the DNA glycosylase MPG family
A3O05_RS10590	COG0488	(ABC) transporter
A3O05_RS10600	COG0647	UMP catabolic process
A3O05_RS10615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3O05_RS10635	COG0504	CTP synthase activity
A3O05_RS10640	COG0494	nUDIX hydrolase
A3O05_RS10660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A3O05_RS10675	COG1160	GTP binding
A3O05_RS10725	COG3976	FMN-binding domain protein
A3O05_RS10725	COG1053	succinate dehydrogenase
A3O05_RS10755	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS10815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3O05_RS10815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3O05_RS10830	COG1253	flavin adenine dinucleotide binding
A3O05_RS10835	COG1253	flavin adenine dinucleotide binding
A3O05_RS10845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3O05_RS10910	COG0830	nickel cation binding
A3O05_RS10925	COG1252	NADH dehydrogenase
A3O05_RS10935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS10970	COG0243	molybdopterin cofactor binding
A3O05_RS10980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3O05_RS10995	COG1058	Belongs to the CinA family
A3O05_RS10995	COG1546	Belongs to the CinA family
A3O05_RS11005	COG4977	sequence-specific DNA binding
A3O05_RS11010	COG1741	Belongs to the pirin family
A3O05_RS11035	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A3O05_RS11060	COG0277	FAD linked oxidase domain protein
A3O05_RS11070	COG1309	transcriptional regulator
A3O05_RS11085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A3O05_RS11090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3O05_RS11095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3O05_RS11120	COG4290	ribonuclease
A3O05_RS11150	COG3883	PFAM NLP P60 protein
A3O05_RS11150	COG0791	NLP P60 protein
A3O05_RS11185	COG0477	Major facilitator Superfamily
A3O05_RS11205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3O05_RS11210	COG0067	glutamate synthase
A3O05_RS11210	COG0069	glutamate synthase activity
A3O05_RS11210	COG0070	glutamate synthase
A3O05_RS11240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3O05_RS11255	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS11270	COG0443	Heat shock 70 kDa protein
A3O05_RS11275	COG0596	Alpha beta hydrolase
A3O05_RS11295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3O05_RS11305	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A3O05_RS11325	COG2890	protein-(glutamine-N5) methyltransferase activity
A3O05_RS11385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A3O05_RS11390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3O05_RS11390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3O05_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS11405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3O05_RS11410	COG1982	Orn Lys Arg decarboxylase major
A3O05_RS11465	COG0028	Belongs to the TPP enzyme family
A3O05_RS11475	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS11500	COG2957	Belongs to the agmatine deiminase family
A3O05_RS11505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O05_RS11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O05_RS11565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3O05_RS11580	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3O05_RS11600	COG0640	Transcriptional regulator
A3O05_RS11610	COG0798	PFAM Bile acid sodium symporter
A3O05_RS11615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3O05_RS11620	COG0390	transport system, permease component
A3O05_RS11640	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS11645	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3O05_RS11710	COG0210	DNA helicase
A3O05_RS11715	COG0745	RESPONSE REGULATOR receiver
A3O05_RS11720	COG2205	protein histidine kinase activity
A3O05_RS11735	COG1917	Cupin 2, conserved barrel domain protein
A3O05_RS11740	COG3707	response regulator
A3O05_RS11780	COG3467	pyridoxamine 5'-phosphate
A3O05_RS11785	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3O05_RS11805	COG0640	Transcriptional regulator
A3O05_RS11825	COG1309	transcriptional regulator
A3O05_RS11830	COG2072	flavoprotein involved in K transport
A3O05_RS11840	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS11845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3O05_RS11850	COG0561	phosphatase activity
A3O05_RS11855	COG0673	inositol 2-dehydrogenase activity
A3O05_RS11860	COG0738	Major facilitator superfamily
A3O05_RS11945	COG1271	oxidase subunit
A3O05_RS11950	COG1294	oxidase, subunit
A3O05_RS11955	COG4988	ABC transporter
A3O05_RS11960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3O05_RS11985	COG1946	Acyl-CoA thioesterase
A3O05_RS12030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3O05_RS12035	COG1846	Transcriptional regulator
A3O05_RS12070	COG0483	inositol monophosphate 1-phosphatase activity
A3O05_RS12080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3O05_RS12085	COG0131	Imidazoleglycerol-phosphate dehydratase
A3O05_RS12090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3O05_RS12115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3O05_RS12130	COG1309	transcriptional regulator
A3O05_RS12150	COG0583	DNA-binding transcription factor activity
A3O05_RS12155	COG0579	oxidoreductase
A3O05_RS12195	COG2755	lipolytic protein G-D-S-L family
A3O05_RS12195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3O05_RS12250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A3O05_RS12270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A3O05_RS12275	COG2814	Major facilitator Superfamily
A3O05_RS12280	COG0583	DNA-binding transcription factor activity
A3O05_RS12330	COG2239	Acts as a magnesium transporter
A3O05_RS12360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A3O05_RS12370	COG2304	oxidoreductase activity
A3O05_RS12380	COG0714	Associated with various cellular activities
A3O05_RS12390	COG3883	PFAM NLP P60 protein
A3O05_RS12390	COG0791	NLP P60 protein
A3O05_RS12400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A3O05_RS12405	COG1309	transcriptional regulator
A3O05_RS12430	COG0488	(ABC) transporter
A3O05_RS12445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3O05_RS12460	COG0456	acetyltransferase
A3O05_RS12470	COG2151	metal-sulfur cluster biosynthetic enzyme
A3O05_RS12485	COG0396	ATPase activity
A3O05_RS12510	COG1131	(ABC) transporter
A3O05_RS12550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A3O05_RS12625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3O05_RS12685	COG0531	amino acid
A3O05_RS12740	COG2011	ABC-type metal ion transport system permease component
A3O05_RS12745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3O05_RS12765	COG0477	Major facilitator Superfamily
A3O05_RS12800	COG0657	acetylesterase activity
A3O05_RS12805	COG1953	Uracil, thiamine, allantoin
A3O05_RS12815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3O05_RS12820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O05_RS12830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A3O05_RS12840	COG1758	RNA polymerase activity
A3O05_RS12860	COG0284	orotidine-5'-phosphate decarboxylase activity
A3O05_RS12865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3O05_RS12870	COG0505	Belongs to the CarA family
A3O05_RS12890	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A3O05_RS12910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3O05_RS12920	COG0006	proline dipeptidase activity
A3O05_RS12935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A3O05_RS12940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3O05_RS12955	COG4106	trans-aconitate 2-methyltransferase activity
A3O05_RS12970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A3O05_RS12985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3O05_RS13035	COG0701	Predicted permease
A3O05_RS13060	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O05_RS13100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A3O05_RS13110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3O05_RS13120	COG0747	negative chemotaxis
A3O05_RS13125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3O05_RS13140	COG2255	four-way junction helicase activity
A3O05_RS13150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A3O05_RS13185	COG1946	Acyl-CoA thioesterase
A3O05_RS13190	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3O05_RS13200	COG0438	transferase activity, transferring glycosyl groups
A3O05_RS13240	COG4762	Protein conserved in bacteria
A3O05_RS13310	COG1309	transcriptional regulator
A3O05_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS13390	COG4221	oxidoreductase activity
A3O05_RS13400	COG3835	regulator
A3O05_RS13405	COG0514	ATP-dependent DNA helicase (RecQ)
A3O05_RS13520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O05_RS13535	COG2080	2 iron, 2 sulfur cluster binding
A3O05_RS13535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A3O05_RS13550	COG0402	S-adenosylhomocysteine deaminase activity
A3O05_RS13570	COG2233	PERMEase
A3O05_RS13590	COG1953	Uracil, thiamine, allantoin
A3O05_RS13600	COG1301	dicarboxylic acid transport
A3O05_RS13610	COG4266	Belongs to the allantoicase family
A3O05_RS13635	COG0501	Belongs to the peptidase M48B family
A3O05_RS13650	COG0477	Major facilitator Superfamily
A3O05_RS13705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O05_RS13715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3O05_RS13755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3O05_RS13780	COG3253	May function as heme-dependent peroxidase
A3O05_RS13785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A3O05_RS13790	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A3O05_RS13800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A3O05_RS13815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3O05_RS13820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O05_RS13825	COG0531	amino acid
A3O05_RS13830	COG0569	domain protein
A3O05_RS13860	COG0702	epimerase
A3O05_RS13875	COG0756	dUTP diphosphatase activity
A3O05_RS13920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3O05_RS13970	COG3220	belongs to the UPF0276 family
A3O05_RS14045	COG1388	LysM domain
A3O05_RS14060	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS14070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3O05_RS14090	COG1196	nuclear chromosome segregation
A3O05_RS14110	COG1126	abc transporter atp-binding protein
A3O05_RS14115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O05_RS14120	COG0765	amino acid transport
A3O05_RS14125	COG0765	amino acid transport
A3O05_RS14175	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3O05_RS14180	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3O05_RS14195	COG1842	Phage shock protein A
A3O05_RS14200	COG1396	sequence-specific DNA binding
A3O05_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS14220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A3O05_RS14275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3O05_RS14280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3O05_RS14295	COG3214	Protein conserved in bacteria
A3O05_RS14335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A3O05_RS14345	COG0659	secondary active sulfate transmembrane transporter activity
A3O05_RS14355	COG0686	Belongs to the AlaDH PNT family
A3O05_RS14365	COG2072	flavoprotein involved in K transport
A3O05_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS14440	COG2977	Belongs to the P-Pant transferase superfamily
A3O05_RS14445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3O05_RS14465	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS14470	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS14475	COG1024	Enoyl-CoA hydratase
A3O05_RS14500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3O05_RS14525	COG1017	nitric oxide dioxygenase activity
A3O05_RS14525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3O05_RS14530	COG1959	2 iron, 2 sulfur cluster binding
A3O05_RS14575	COG1648	precorrin-2 dehydrogenase activity
A3O05_RS14575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3O05_RS14600	COG0604	alcohol dehydrogenase
A3O05_RS14600	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS14600	COG3321	synthase
A3O05_RS14660	COG0579	oxidoreductase
A3O05_RS14680	COG1492	cobalamin metabolic process
A3O05_RS14690	COG1376	ErfK ybiS ycfS ynhG family protein
A3O05_RS14715	COG0750	zinc metalloprotease
A3O05_RS14740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A3O05_RS14805	COG0528	UMP kinase activity
A3O05_RS14810	COG3973	AAA domain
A3O05_RS14825	COG2723	6-phospho-beta-galactosidase activity
A3O05_RS14860	COG1309	transcriptional regulator
A3O05_RS14900	COG0583	DNA-binding transcription factor activity
A3O05_RS14930	COG0792	nuclease activity
A3O05_RS14990	COG0336	Belongs to the RNA methyltransferase TrmD family
A3O05_RS15030	COG1686	Belongs to the peptidase S11 family
A3O05_RS15050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A3O05_RS15070	COG1304	FMN binding
A3O05_RS15120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A3O05_RS15125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A3O05_RS15145	COG0571	ribonuclease III activity
A3O05_RS15155	COG3599	regulation of cell shape
A3O05_RS15195	COG0742	ribosomal rna small subunit methyltransferase
A3O05_RS15200	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3O05_RS15215	COG0657	acetylesterase activity
A3O05_RS15220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS15240	COG2124	cytochrome p450
A3O05_RS15255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3O05_RS15260	COG1461	Dihydroxyacetone kinase
A3O05_RS15270	COG1024	Enoyl-CoA hydratase
A3O05_RS15295	COG1181	Belongs to the D-alanine--D-alanine ligase family
A3O05_RS15300	COG0626	cystathionine gamma-synthase activity
A3O05_RS15305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A3O05_RS15370	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3O05_RS15385	COG2271	Major facilitator Superfamily
A3O05_RS15420	COG0583	DNA-binding transcription factor activity
A3O05_RS15450	COG0440	acetolactate synthase activity
A3O05_RS15465	COG1748	Saccharopine dehydrogenase
A3O05_RS15470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3O05_RS15490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O05_RS15510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3O05_RS15520	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O05_RS15535	COG0745	RESPONSE REGULATOR receiver
A3O05_RS15540	COG2205	protein histidine kinase activity
A3O05_RS15565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O05_RS15595	COG1024	Enoyl-CoA hydratase
A3O05_RS15600	COG0778	Nitroreductase
A3O05_RS15610	COG2252	PERMEase
A3O05_RS15650	COG2197	response regulator
A3O05_RS15655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A3O05_RS15665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3O05_RS15690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A3O05_RS15705	COG1309	transcriptional regulator
A3O05_RS15735	COG0110	maltose O-acetyltransferase activity
A3O05_RS15740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A3O05_RS15765	COG1119	ATPase activity
A3O05_RS15775	COG2364	Membrane
A3O05_RS15780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O05_RS15795	COG4607	ABC-type enterochelin transport system periplasmic component
A3O05_RS15845	COG1064	alcohol dehydrogenase
A3O05_RS15865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3O05_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS15930	COG0477	Major facilitator Superfamily
A3O05_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS16005	COG1335	isochorismatase
A3O05_RS16015	COG2855	membrane
A3O05_RS16025	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS16055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3O05_RS16110	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O05_RS16125	COG0183	Belongs to the thiolase family
A3O05_RS16160	COG1309	transcriptional regulator
A3O05_RS16185	COG0789	Transcriptional regulator
A3O05_RS16195	COG0028	Belongs to the TPP enzyme family
A3O05_RS16580	COG0582	viral genome integration into host DNA
A3O05_RS16600	COG2177	Part of the ABC transporter FtsEX involved in
A3O05_RS16605	COG2884	Cell division ATP-binding protein ftsE
A3O05_RS16615	COG0668	transmembrane transport
A3O05_RS16655	COG0483	inositol monophosphate 1-phosphatase activity
A3O05_RS16660	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS16665	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS16680	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS16690	COG0542	response to heat
A3O05_RS16735	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3O05_RS16740	COG3011	Protein conserved in bacteria
A3O05_RS16755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O05_RS16760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O05_RS16770	COG0300	oxidoreductase activity
A3O05_RS16775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O05_RS16810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3O05_RS16810	COG0475	glutathione-regulated potassium exporter activity
A3O05_RS16825	COG0596	Alpha beta hydrolase
A3O05_RS16840	COG0745	RESPONSE REGULATOR receiver
A3O05_RS16850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3O05_RS16850	COG2146	nitrite reductase [NAD(P)H] activity
A3O05_RS16855	COG2223	nitrite transmembrane transporter activity
A3O05_RS16895	COG0513	Belongs to the DEAD box helicase family
A3O05_RS16910	COG0406	alpha-ribazole phosphatase activity
A3O05_RS16930	COG1597	lipid kinase activity
A3O05_RS16945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3O05_RS16955	COG1595	DNA-templated transcription, initiation
A3O05_RS16960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A3O05_RS16965	COG2135	peptidase activity
A3O05_RS16970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A3O05_RS16975	COG1162	GTPase activity
A3O05_RS17010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3O05_RS17105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3O05_RS17110	COG3321	synthase
A3O05_RS17110	COG0604	alcohol dehydrogenase
A3O05_RS17115	COG0604	alcohol dehydrogenase
A3O05_RS17115	COG3321	synthase
A3O05_RS17120	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS17130	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS17135	COG0653	protein targeting
A3O05_RS17145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O05_RS17150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A3O05_RS17160	COG1309	transcriptional regulator
A3O05_RS17175	COG5401	PFAM Sporulation and spore germination
A3O05_RS17180	COG5002	protein histidine kinase activity
A3O05_RS17190	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS17195	COG1285	pathogenesis
A3O05_RS17225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3O05_RS17230	COG0531	amino acid
A3O05_RS17240	COG1482	cell wall glycoprotein biosynthetic process
A3O05_RS17270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A3O05_RS17275	COG0778	Nitroreductase
A3O05_RS17275	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
A3O05_RS17290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3O05_RS17305	COG1316	TRANSCRIPTIONal
A3O05_RS17325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3O05_RS17335	COG2175	clavaminate synthase activity
A3O05_RS17360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3O05_RS17360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3O05_RS17370	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS17385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O05_RS17405	COG3265	gluconokinase activity
A3O05_RS17410	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS17425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS17445	COG4770	biotin carboxylase activity
A3O05_RS17455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A3O05_RS17475	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS17480	COG1309	transcriptional regulator
A3O05_RS17485	COG1201	RNA secondary structure unwinding
A3O05_RS17500	COG0564	pseudouridine synthase activity
A3O05_RS17520	COG1473	amidohydrolase
A3O05_RS17520	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3O05_RS17535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3O05_RS17550	COG3883	PFAM NLP P60 protein
A3O05_RS17550	COG0791	NLP P60 protein
A3O05_RS17595	COG2009	succinate dehydrogenase
A3O05_RS17610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A3O05_RS17615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O05_RS17620	COG1595	DNA-templated transcription, initiation
A3O05_RS17630	COG1686	Belongs to the peptidase S11 family
A3O05_RS17645	COG0708	Exodeoxyribonuclease III
A3O05_RS17705	COG1733	regulation of RNA biosynthetic process
A3O05_RS17710	COG2910	NAD(P)H-binding
A3O05_RS17715	COG1131	(ABC) transporter
A3O05_RS17715	COG1716	ATPase activity
A3O05_RS17715	COG0842	Transport permease protein
A3O05_RS17720	COG1357	PFAM Pentapeptide repeats (8 copies)
A3O05_RS17735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A3O05_RS17740	COG0587	DNA-directed DNA polymerase activity
A3O05_RS17745	COG1073	alpha beta
A3O05_RS17750	COG1309	transcriptional regulator
A3O05_RS17815	COG0519	Catalyzes the synthesis of GMP from XMP
A3O05_RS17815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3O05_RS17825	COG0516	GMP reductase activity
A3O05_RS17885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A3O05_RS17900	COG0456	acetyltransferase
A3O05_RS17925	COG0076	glutamate decarboxylase activity
A3O05_RS17935	COG2267	carboxylic ester hydrolase activity
A3O05_RS17940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3O05_RS17965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS17975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3O05_RS17980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3O05_RS18015	COG1404	Belongs to the peptidase S8 family
A3O05_RS18045	COG2267	carboxylic ester hydrolase activity
A3O05_RS18100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A3O05_RS18105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O05_RS18115	COG2268	Band 7 protein
A3O05_RS18125	COG1088	dTDP-glucose 4,6-dehydratase activity
A3O05_RS18130	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A3O05_RS18175	COG0616	signal peptide processing
A3O05_RS18190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS18210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3O05_RS18220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3O05_RS18230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3O05_RS18240	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O05_RS18265	COG0477	Major facilitator Superfamily
A3O05_RS18280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3O05_RS18320	COG0088	Forms part of the polypeptide exit tunnel
A3O05_RS18325	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3O05_RS18330	COG0051	transcription antitermination factor activity, RNA binding
A3O05_RS18365	COG0531	amino acid
A3O05_RS18395	COG0535	radical SAM domain protein
A3O05_RS18420	COG1834	amidinotransferase
A3O05_RS18425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3O05_RS18430	COG0531	amino acid
A3O05_RS18475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A3O05_RS18480	COG1309	transcriptional regulator
A3O05_RS18505	COG1024	Enoyl-CoA hydratase
A3O05_RS18520	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS18550	COG1113	amino acid transport
A3O05_RS18565	COG0085	RNA polymerase activity
A3O05_RS18570	COG0243	molybdopterin cofactor binding
A3O05_RS18625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O05_RS18640	COG0277	FAD linked oxidase domain protein
A3O05_RS18660	COG4941	Belongs to the sigma-70 factor family
A3O05_RS18695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3O05_RS18735	COG0783	Belongs to the Dps family
A3O05_RS18740	COG0693	protein deglycase activity
A3O05_RS18785	COG1404	Belongs to the peptidase S8 family
A3O05_RS18805	COG1280	lysine exporter protein (LysE YggA)
A3O05_RS18875	COG0501	Belongs to the peptidase M48B family
A3O05_RS18880	COG0142	geranyltranstransferase activity
A3O05_RS18885	COG0644	oxidoreductase
A3O05_RS18895	COG0438	transferase activity, transferring glycosyl groups
A3O05_RS18915	COG4948	Mandelate Racemase Muconate Lactonizing
A3O05_RS18940	COG3706	GGDEF domain
A3O05_RS18955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O05_RS18965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A3O05_RS18970	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS18975	COG4221	oxidoreductase activity
A3O05_RS19020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3O05_RS19025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3O05_RS19035	COG0542	response to heat
A3O05_RS19060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS19105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3O05_RS19110	COG1333	cytochrome c biogenesis protein
A3O05_RS19115	COG0785	Cytochrome C biogenesis protein
A3O05_RS19125	COG0406	alpha-ribazole phosphatase activity
A3O05_RS19145	COG3590	peptidase
A3O05_RS19190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3O05_RS19190	COG1587	Uroporphyrinogen-III synthase
A3O05_RS19215	COG2030	dehydratase
A3O05_RS19240	COG2070	2-Nitropropane dioxygenase
A3O05_RS19260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3O05_RS19265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O05_RS19370	COG1309	transcriptional regulator
A3O05_RS19380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS19430	COG2072	flavoprotein involved in K transport
A3O05_RS19445	COG2072	flavoprotein involved in K transport
A3O05_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS19455	COG0657	acetylesterase activity
A3O05_RS19460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O05_RS19470	COG0745	RESPONSE REGULATOR receiver
A3O05_RS19475	COG5002	protein histidine kinase activity
A3O05_RS19485	COG2072	flavoprotein involved in K transport
A3O05_RS19500	COG0300	oxidoreductase activity
A3O05_RS19555	COG2814	Major facilitator Superfamily
A3O05_RS19650	COG2733	membrane
A3O05_RS19660	COG2326	polyphosphate kinase activity
A3O05_RS19665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O05_RS19700	COG2224	Isocitrate lyase
A3O05_RS19740	COG2226	methyltransferase
A3O05_RS19790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A3O05_RS19825	COG0667	Aldo Keto reductase
A3O05_RS19845	COG4552	Acetyltransferase involved in intracellular survival and related
A3O05_RS19850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS19875	COG1505	serine-type exopeptidase activity
A3O05_RS19895	COG1073	alpha beta
A3O05_RS19900	COG2326	polyphosphate kinase activity
A3O05_RS19915	COG2223	nitrite transmembrane transporter activity
A3O05_RS19920	COG0640	Transcriptional regulator
A3O05_RS19950	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A3O05_RS19970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A3O05_RS19995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS20000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS20015	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS20020	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS20025	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS20035	COG2070	2-Nitropropane dioxygenase
A3O05_RS20045	COG1024	Enoyl-CoA hydratase
A3O05_RS20050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A3O05_RS20055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS20090	COG4638	Rieske (2fe-2S)
A3O05_RS20130	COG0175	sulfate reduction
A3O05_RS20200	COG2814	Major facilitator Superfamily
A3O05_RS20210	COG0351	phosphomethylpyrimidine kinase
A3O05_RS20220	COG1252	NADH dehydrogenase
A3O05_RS20230	COG1309	transcriptional regulator
A3O05_RS20240	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS20275	COG0494	nUDIX hydrolase
A3O05_RS20285	COG2234	aminopeptidase activity
A3O05_RS20290	COG2234	aminopeptidase activity
A3O05_RS20300	COG1131	(ABC) transporter
A3O05_RS20305	COG2022	thiamine diphosphate biosynthetic process
A3O05_RS20340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O05_RS20345	COG0515	serine threonine protein kinase
A3O05_RS20350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3O05_RS20380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3O05_RS20385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS20390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS20395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS20405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O05_RS20410	COG1126	abc transporter atp-binding protein
A3O05_RS20415	COG0765	amino acid transport
A3O05_RS20450	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3O05_RS20480	COG1994	Peptidase M50
A3O05_RS20500	COG0586	Pfam SNARE associated Golgi protein
A3O05_RS20530	COG4221	oxidoreductase activity
A3O05_RS20550	COG0542	response to heat
A3O05_RS20575	COG0789	Transcriptional regulator
A3O05_RS20580	COG0484	heat shock protein binding
A3O05_RS20585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3O05_RS20660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3O05_RS20660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A3O05_RS20700	COG2181	nitrate reductase activity
A3O05_RS20700	COG0247	lactate metabolic process
A3O05_RS20710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3O05_RS20750	COG3345	alpha-galactosidase
A3O05_RS20755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3O05_RS20760	COG1305	Transglutaminase-like
A3O05_RS20775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O05_RS20830	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS20840	COG0454	-acetyltransferase
A3O05_RS20895	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS20900	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS20915	COG3268	Saccharopine dehydrogenase
A3O05_RS20920	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS20935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3O05_RS20940	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS21000	COG2837	iron assimilation
A3O05_RS21025	COG1309	transcriptional regulator
A3O05_RS21030	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3O05_RS21045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3O05_RS21050	COG1984	allophanate hydrolase subunit 2
A3O05_RS21115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3O05_RS21120	COG1802	Transcriptional regulator
A3O05_RS21150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O05_RS21160	COG0473	3-isopropylmalate dehydrogenase activity
A3O05_RS21175	COG1053	succinate dehydrogenase
A3O05_RS21195	COG0640	Transcriptional regulator
A3O05_RS21245	COG2318	DinB family
A3O05_RS21250	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS21265	COG1660	Displays ATPase and GTPase activities
A3O05_RS21275	COG0183	Belongs to the thiolase family
A3O05_RS21280	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS21285	COG2030	dehydratase
A3O05_RS21300	COG0659	secondary active sulfate transmembrane transporter activity
A3O05_RS21305	COG1309	transcriptional regulator
A3O05_RS21310	COG0861	Integral membrane protein TerC family
A3O05_RS21335	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS21350	COG1472	Belongs to the glycosyl hydrolase 3 family
A3O05_RS21355	COG4941	Belongs to the sigma-70 factor family
A3O05_RS21405	COG4981	capsule polysaccharide biosynthetic process
A3O05_RS21440	COG0438	transferase activity, transferring glycosyl groups
A3O05_RS21485	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3O05_RS21530	COG2197	response regulator
A3O05_RS21535	COG3850	Histidine kinase
A3O05_RS21555	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3O05_RS21585	COG2409	Drug exporters of the RND superfamily
A3O05_RS21650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O05_RS21660	COG2197	response regulator
A3O05_RS21690	COG2353	YceI-like domain
A3O05_RS21710	COG2409	Drug exporters of the RND superfamily
A3O05_RS21725	COG4552	Acetyltransferase involved in intracellular survival and related
A3O05_RS21730	COG1832	CoA-binding protein
A3O05_RS21745	COG3590	peptidase
A3O05_RS21750	COG1376	ErfK ybiS ycfS ynhG family protein
A3O05_RS21755	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS21765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O05_RS21775	COG1937	Protein conserved in bacteria
A3O05_RS21800	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS21805	COG4122	O-methyltransferase activity
A3O05_RS21820	COG2267	carboxylic ester hydrolase activity
A3O05_RS21850	COG1704	LemA family
A3O05_RS21860	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS21915	COG1024	Enoyl-CoA hydratase
A3O05_RS21920	COG1802	Transcriptional regulator
A3O05_RS21930	COG2267	carboxylic ester hydrolase activity
A3O05_RS21935	COG1309	transcriptional regulator
A3O05_RS21965	COG0435	Glutathione S-transferase
A3O05_RS22005	COG1024	Enoyl-CoA hydratase
A3O05_RS22015	COG2211	Major facilitator Superfamily
A3O05_RS22020	COG2365	Tyrosine phosphatase family
A3O05_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS22090	COG1012	belongs to the aldehyde dehydrogenase family
A3O05_RS22105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O05_RS22110	COG1960	acyl-CoA dehydrogenase activity
A3O05_RS22115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O05_RS22130	COG2226	methyltransferase
A3O05_RS22145	COG1396	sequence-specific DNA binding
A3O05_RS22145	COG3800	Transcriptional regulator
A3O05_RS22155	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3O05_RS22195	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS22255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3O05_RS22265	COG0129	dihydroxy-acid dehydratase activity
A3O05_RS22285	COG2186	Transcriptional regulator
A3O05_RS22315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3O05_RS22320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O05_RS22330	COG0723	plastoquinol--plastocyanin reductase activity
A3O05_RS22350	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS22390	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS22405	COG0318	PFAM AMP-dependent synthetase and ligase
A3O05_RS22410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O05_RS22415	COG1136	(ABC) transporter
A3O05_RS22425	COG1104	cysteine desulfurase activity
A3O05_RS22485	COG1309	transcriptional regulator
A3O05_RS22535	COG1819	glycosyl
A3O05_RS22645	COG3263	regulation of cellular component size
A3O05_RS22725	COG1595	DNA-templated transcription, initiation
A3O05_RS22735	COG0783	Belongs to the Dps family
A3O05_RS22775	COG1252	NADH dehydrogenase
A3O05_RS22795	COG1937	Protein conserved in bacteria
A3O05_RS22820	COG1403	HNH endonuclease
A3O05_RS22890	COG2140	Oxalate decarboxylase
A3O05_RS22915	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A3O05_RS22935	COG1376	ErfK ybiS ycfS ynhG family protein
A3O05_RS22955	COG2030	dehydratase
A3O05_RS22965	COG3757	hydrolase, family 25
A3O05_RS23025	COG0583	DNA-binding transcription factor activity
A3O05_RS23030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O05_RS23045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O05_RS23050	COG3757	hydrolase, family 25
A3O05_RS23115	COG0629	single-stranded DNA binding
A3O05_RS23130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3O05_RS23160	COG1260	myo-inositol-1-phosphate synthase
A3O05_RS23170	COG1113	amino acid transport
A3O05_RS23185	COG1309	transcriptional regulator
A3O05_RS23190	COG1028	Short-chain dehydrogenase reductase Sdr
A3O05_RS23205	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3O05_RS23210	COG0022	dehydrogenase e1 component
A3O05_RS23225	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A3O05_RS23230	COG2311	Membrane
A3O05_RS23295	COG0617	tRNA 3'-terminal CCA addition
A3O05_RS23315	COG1595	DNA-templated transcription, initiation
A3O05_RS23335	COG3409	Peptidoglycan-binding domain 1 protein
A3O05_RS23335	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3O05_RS23345	COG2124	cytochrome p450
A3O05_RS23375	COG1192	Involved in chromosome partitioning
A3O05_RS23380	COG0357	Ribosomal RNA small subunit methyltransferase G
A3O05_RS23390	COG0706	membrane insertase activity
A3O05_RS23470	COG0765	amino acid transport
A3O05_RS23625	COG1074	ATP-dependent DNA helicase activity
A3O05_RS23735	COG1403	HNH endonuclease
A3O05_RS23795	COG1254	Belongs to the acylphosphatase family
A3O05_RS23905	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A3O05_RS23975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O05_RS24050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane